<?xml version="1.0" encoding="UTF-8"?>
<uniprot xmlns="http://uniprot.org/uniprot"
 xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance"
 xsi:schemaLocation="http://uniprot.org/uniprot http://www.uniprot.org/docs/uniprot.xsd">
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAJ5</accession>
    <name>A0A5C6ZAJ5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Threonine--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Threonyl-tRNA synthetase</fullName>
            <shortName evidence="9">ThrRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 12" type="primary">thrS</name>
        <name evidence="12" type="ORF">ESY86_18770</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + H(+) + L-threonyl-tRNA(Thr)</text>
            <dbReference type="Rhea" id="RHEA:24624"/>
            <dbReference type="Rhea" id="RHEA-COMP:9670"/>
            <dbReference type="Rhea" id="RHEA-COMP:9704"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78534"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.3" evidence="9"/>
    <dbReference type="EMBL" id="VORO01000033">
        <property type="protein sequence ID" value="TXD86969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004829">
        <property type="term" value="F:threonine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006435">
        <property type="term" value="P:threonyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00771">
        <property type="entry name" value="ThrRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00184">
        <property type="entry name" value="Thr_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002320">
        <property type="entry name" value="Thr-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033728">
        <property type="entry name" value="ThrRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11451">
        <property type="entry name" value="PTHR11451"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02824">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01047">
        <property type="entry name" value="TRNASYNTHTHR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="SSF55186"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="SSF81271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00418">
        <property type="entry name" value="thrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 9 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 9" id="KW-0820">tRNA-binding</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="TGS" evidence="11">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="10">
        <location>
            <begin position="242"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="337"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="388"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="518"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TXD86969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="647" mass="73710" checksum="442CA558810B5560" modified="2019-11-13" version="1">MIKITLPDGTEKKFDKGVTPLDVAKSISEGFARNVISANFNGTTLETTSSLNEDGSLILYTWNDDEGKKAFWHSSAHILAQALEELYPGVKLSIGPAIENGFYYDIDLGEHSISEKDFKSIEDKMIEIARGKHTFEMRAASKAEALDLYRSQDNEYKVELIENLEDGTITFCDHSTFTDLCRGGHIPNTGIVKAVKLLSVAGAYWRGDENNKQLTRIYGISFPKQKDLTEYLNLLEEAKKRDHRKLGKELELFTFSQKVGQGLPLWLPKGAALRERLENFLKAAQKKAGYEMVVTPHIGQKELYVTSGHYEKYGADSFQPILTPKEGEEFLLKPMNCPHHCEIYNAMPFSYKELPKRYAEFGTVYRYEQSGELHGLTRVRGFTQDDAHIFCTPDQLDKEFKDVIDLVLYVFGSLGFENFKAQVSLRDTENPEKYIGSDENWKKAEDAILNAAIDKGLDYVVVKGEAAFYGPKLDFMVKDALGRNWQLGTIQVDYNLPERFDLTYKGSDNELHRPVMIHRAPFGSMERFIAILLEHTGGNFPIWLMPTQAIILSISEKYEKYSQKVLNLLEKHEIRALVDHRNETIGKKIREAEMNKIPYMLIIGEKEEDENMISVRKHGGEELGMISVETLSEVIENEINKTLKTFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZB60</accession>
    <name>A0A5C6ZB60_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">EF-hand domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18745</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000033">
        <property type="protein sequence ID" value="TXD86965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="SSF47473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="1">
        <location>
            <begin position="17"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="1">
        <location>
            <begin position="55"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="88" mass="10072" checksum="50A5CC5659DBD266" modified="2019-11-13" version="1">MATKEMILEKIQILITNHFQTPEEAFAFFDKDSNGKLSKDELVALLKQAEISGFLTGMVAKRLLEGYDKDGNGRIDWQEFKMAINEME</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBL0</accession>
    <name>A0A5C6ZBL0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000036">
        <property type="protein sequence ID" value="TXD86850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="207" mass="24737" checksum="C8E07662B1202C6D" modified="2019-11-13" version="1">MNIRFTILTFLFTQIFYCQVNIQEDNLTIEYAKTKKASQSLGMVTNVRTKSKEVVQYNIKIRVEMLDNKKRSFDANKFSLVDYQDSIRLRPIDVAYTNLTDKWHFIKLIKNKPKYKSLEKRYKPDIKDTFLDYEFEGINNLTIPICYEAYDKYKISFKNPDKECHESYFEPKDLRKRNVNLYFPMLKSAESATLYYGNTKITEINLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBP0</accession>
    <name>A0A5C6ZBP0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20505</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000081">
        <property type="protein sequence ID" value="TXD86212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="77" mass="8977" checksum="57715DD6351C512A" modified="2019-11-13" version="1">MIHNPSQREDVGGKHQHRQLNHEQNSTQVYGFKASRFENKQARFKRDSDSSKAIVGVFHQQSQPSKTKAHINYQMQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBS8</accession>
    <name>A0A5C6ZBS8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TIGR01777 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_17510</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000027">
        <property type="protein sequence ID" value="TXD87232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013549">
        <property type="entry name" value="DUF1731"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010099">
        <property type="entry name" value="SDR39U1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08338">
        <property type="entry name" value="DUF1731"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01777">
        <property type="entry name" value="yfcH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="2">
        <location>
            <begin position="4"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1731" evidence="3">
        <location>
            <begin position="254"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD87232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="305" mass="33858" checksum="BC6BA6884170874D" modified="2019-11-13" version="1">MKKVLITGATGMIGSEIVKVCHNKGIAVNYLTTSKDKLSSKENYQGFYWNPNENEIDPKCLEGVDAIINMVGATIAERWTSDYKKEIISSRTETAELLKNTIKKHNFPVKQMVSASAIGLYPDSLTNYYEEDFTKVSDSFLGQVVEKWEAAVDEFKELGISVAKIRIGLVLSNKGGALPEMAKPIRLGAGAAFGSGDQWQSWIHVKDLARLFVYAVQNDLEGIYNAVSPNPVTNTEVTKTVAQVLDKPLLLPNIPKFVMKLALGEMHILLFESQRVSSNKIQSEGFEFRWVHLEPAIQDLLGSES</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBZ9</accession>
    <name>A0A5C6ZBZ9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_17740</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000028">
        <property type="protein sequence ID" value="TXD87158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="72" mass="8637" checksum="F8237F205A5EEDFC" modified="2019-11-13" version="1">MEYIDYSSVKQKIERENCSKHKKHPKFEKTSKGFEILACCEEFRSDMIKRTKKIMAEETKSAIERMLKNTFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC19</accession>
    <name>A0A5C6ZC19_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000028">
        <property type="protein sequence ID" value="TXD87178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022997775" evidence="1">
        <location>
            <begin position="20"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="121" mass="13626" checksum="4E7399DE6CA1CCD2" modified="2019-11-13" version="1">MKNLLVLAFIMMLLSCSEANDTAPAKVAEIVAESFYQGNDVALKEHTTAEGYANFSNLQKMFAKPKSSKTNFKLIDQDIKDDVAWVKYSTAYDKTPGVFKLVKLDGRWKVTVRTPREQAPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC26</accession>
    <name>A0A5C6ZC26_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Serine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Seryl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">serS</name>
        <name evidence="10" type="ORF">ESY86_18455</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-serine + tRNA(Sec) = AMP + diphosphate + H(+) + L-seryl-tRNA(Sec)</text>
            <dbReference type="Rhea" id="RHEA:42580"/>
            <dbReference type="Rhea" id="RHEA-COMP:9742"/>
            <dbReference type="Rhea" id="RHEA-COMP:10128"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78533"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.11"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.11" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000031">
        <property type="protein sequence ID" value="TXD87039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004828">
        <property type="term" value="F:serine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006434">
        <property type="term" value="P:seryl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00770">
        <property type="entry name" value="SerRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002317">
        <property type="entry name" value="Ser-tRNA-ligase_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015866">
        <property type="entry name" value="Ser-tRNA-synth_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042103">
        <property type="entry name" value="SerRS_1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033729">
        <property type="entry name" value="SerRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43697">
        <property type="entry name" value="PTHR43697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02403">
        <property type="entry name" value="Seryl_tRNA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001529">
        <property type="entry name" value="Ser-tRNA-synth_IIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00981">
        <property type="entry name" value="TRNASYNTHSER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="SSF46589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00414">
        <property type="entry name" value="serS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="9">
        <location>
            <begin position="175"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD87039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="425" mass="47576" checksum="B126ED783CB88F5A" modified="2019-11-13" version="1">MLQVAYIRDHKAEVLKGLAKRQIDASMMIDQVLLLDEARRATQTELDNTLAESNAISKEIGNLFKSGKAAEANELKAKTSQLKEDSKALGEQLNEKVNALNELLYKIPNVPHLDVPAGNSEADNEEVYREGDIPKLHAAAQPHWELAKTYDIIDFELGNKITGAGFPVYKGKGAKLQRALISYFLDKNTAAGYTEYQLPLLVNEASGFGTGQLPDKEGQMYHVGEDDLYLIPTAEVPATNMYRDSLLAETDLPIQLTGYTPCFRREAGSYGAHVRGLNRLHQFDKVEILRIEHPEKSYQALEHMVEHVKTILKELKLPYRILRLCGGDLGFTSALTYDFEVFSTAQDRWLEISSVSNFETFQANRLKLRFKNKEGKTELCHTLNGSALALPRVLAGILENYQTEDGIDIPEVLIPYTGFSKIQNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCE1</accession>
    <name>A0A5C6ZCE1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sugar porter family MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_16075</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000021">
        <property type="protein sequence ID" value="TXD87670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005828">
        <property type="entry name" value="MFS_sugar_transport-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003663">
        <property type="entry name" value="Sugar/inositol_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00083">
        <property type="entry name" value="Sugar_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00171">
        <property type="entry name" value="SUGRTRNSPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00879">
        <property type="entry name" value="SP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00217">
        <property type="entry name" value="SUGAR_TRANSPORT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="103"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="178"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="251"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="296"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="321"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="347"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="384"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="424"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="7">
        <location>
            <begin position="10"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD87670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="460" mass="50623" checksum="5926C4D7553CBAAC" modified="2019-11-13" version="1">MNKRTFLLLITSVSALGGLLFGYDTGVINGAQFYLSKYFELDAAMKGWVVSSALVGCFVGAIVAGPLSIKIGRKYSLILSAILFSISAWGSGLPSMLPESVDLLVMFRIIGGLGIGIASMNAPMYIAEIAPPRKRGNLVSYYQLAIVVGFFIVFLATYTIGSNLTEEQNLAIGWRRMFWSELIPAGLFLILLFFVPQSPRWLAMKGKKKESLRILTKILGAEEAQRESVEIEKSLQKKNTGVKINYFSKGILTIIVIGTTLSVLQQFTGINAVLYYGADIFEQSLGFGKEDVLLQQILLAFVNLIFTFIAMATVDRIGRKPLIYIGSAGMLLGFLILGVTIQQQSLGILSLIGVLLFVASFAMSMGPVVWVLLSEMFPNNIRSVAMSVAVAAQWAANFVVSQSFPIVTESEVNNNAFWNGSLPYFIFIGFIIFIVVFTYKFIPETKGRSLEELEDIWDVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCJ1</accession>
    <name>A0A5C6ZCJ1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">T9SS type A sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_16555</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000023">
        <property type="protein sequence ID" value="TXD87505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023147990" evidence="1">
        <location>
            <begin position="19"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="domain" description="Por_Secre_tail" evidence="2">
        <location>
            <begin position="522"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="593" mass="63604" checksum="3E0835C55F4DC873" modified="2019-11-13" version="1">MIKHYALLLFALPFIAFSQTVAFESTISADLSAYSGATSFSGLGEYELFLDSNDGILDKPIILLDGFDPGDTRTISGIYDLLNFTDASGNQNLGDLVRAEGFDVVILNFPRYLRLADATLLNLSDVADTNGDSIIDESDFPAGSSLIDGGADFLERNAMLLLDLINTLNADKVGEEELVIIGPSMGGIISKYTLNYMENQSIAHETRLWISFDAPHLGANVPLGFQHQFNFLGFGLGNLNITQLQPVVNGLLKAPAARQMLIDQFETHLETGSNVAFDPAKLLPEAHPYKAIFDSSVNGLTATGFPQNTRNVAIVNGSGVGNPYLSSNGTEVTPGFTAIDDTFAVPGSPLPTTAQIGLNLTPASATGAALISKILVQINFIGTTTLVDVEANAQANSYSDGVDAASGGLFDLNAFTEGLGNDGIIGLFSNALQLDEFSFIPSVSAMAVEFPNNEIDWYDIDLGTPTSPNATTPFVNWHAPTENQPHVQLNEANVAFALSEILQGSLSNVSFENSADVRIASNPINDALVILSDKLLGRTNLSIIDITGKHVYKATNMVLTQRNRIPLDLESGMYILNIEPKNQTQIRIKFIVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCP4</accession>
    <name>A0A5C6ZCP4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Barnase inhibitor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_19290</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the barstar family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000038">
        <property type="protein sequence ID" value="TXD86798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000468">
        <property type="entry name" value="Barstar"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035905">
        <property type="entry name" value="Barstar-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01337">
        <property type="entry name" value="Barstar"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52038">
        <property type="entry name" value="SSF52038"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Barstar" evidence="2">
        <location>
            <begin position="6"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="97" mass="11465" checksum="3B6D6FBE785FFAC4" modified="2019-11-13" version="1">MQTFIIKGKRLKNWKTFHAEFKKEMHFPDYYGENMDAWIDCIDELSDEPTILQIENGKYLKENVPELFNAILECGAFVNYRKIEVGEKPNLIIATDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCX6</accession>
    <name>A0A5C6ZCX6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">LexA family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18880</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000034">
        <property type="protein sequence ID" value="TXD86929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd06529">
        <property type="entry name" value="S24_LexA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039418">
        <property type="entry name" value="LexA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015927">
        <property type="entry name" value="Peptidase_S24_S26A/B/C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00717">
        <property type="entry name" value="Peptidase_S24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="SSF51306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="8"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="256" mass="29200" checksum="175B977231AD9399" modified="2019-11-13" version="1">MKNIQANIKHLRSLRQFSQERFADELGWSRSMVGSYEEGRSEPPIDRLIDLSNFFNLPIDILVKNDLRKATDSSFIQIGSQRVLFPITVSEDNEDLIEIVPAQASAGYLAGYADPEYIEQLQKIKLPFLPTGTHRAFPIKGDSMLPVKSGSFIVAKYVEDVSDVKNGRTYIVLTKNDGLVYKRVYNFIEARQALQLSSDNKTYEPYDVAIADVLELWEFTCCINTQEYDEKELKMSSIMSMFQDLKVELEAVQKMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD44</accession>
    <name>A0A5C6ZD44_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">50S ribosomal protein L18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rplR</name>
        <name evidence="8" type="ORF">ESY86_14910</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the universal ribosomal protein uL18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01337_B">
        <property type="entry name" value="Ribosomal_L18_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005484">
        <property type="entry name" value="Ribosomal_L18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004389">
        <property type="entry name" value="Ribosomal_L18_bac-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12899">
        <property type="entry name" value="PTHR12899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00861">
        <property type="entry name" value="Ribosomal_L18p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00060">
        <property type="entry name" value="L18_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 7" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD87957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="118" mass="12808" checksum="00D05F64AA836183" modified="2019-11-13" version="1">MALTKNEKRLRIKSRIRKVVSGTEARPRLAVFRSNKEIYAQVVDDVTGVTLAAASSRDKDIASDKGNKTDKATLVGKAVAERAIKAGVNTISFDRGGYQYHGRVKSLAEGAREGGLKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD61</accession>
    <name>A0A5C6ZD61_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_18290</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000030">
        <property type="protein sequence ID" value="TXD87082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="540" mass="62900" checksum="7960CF7FC0DD0197" modified="2019-11-13" version="1">MFYVNDKIDSNQFSQSDIEIVNERFTIFDDVFITKNPVQYRGDLELKLNSSKTSLLEYNISFRDEVIKTDRNISSNQANNFDSFLESESVFINQNLEFTKRLSNKKALQFNLDYATNDLGQNFSIEPSIFNNIEFDNDTQYADSKKHNLSFKALILGRHKKSNYSFVVGGTLDTELFSSALLSQNNLQTISIGSNLNNLEYKFNEIYTQGTYNWILGKFTVSPKYSFRTLNQSLGITQDDISLNSNILLFEPSLSLLYAIDQTSHINFTSRIYRGTNSIQNFYTDGILLDNRILRNNIPDLRLNRNQNYSLTYQKNDLFNQLELSLGGNYIKQRGNFFTDTQIDEFSTLITTFFLPESNENLDFFFNVSKLLPWINTTIKATSNYSIVNFKNILNNSELRNNKSNFFVNSIFFKSAFNSSINFQNKTTHTYQEHRSENLFTNQSIENELKVIFKPTKQLVLSLNYNYVVPSFDRNSNNFSFLESTITYKPKDKNWQLNFTGVNLLNEKIFEQINTSDASINRQRVDLLNRYILLNFGYNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDB4</accession>
    <name>A0A5C6ZDB4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_18895</name>
        <name evidence="4" type="ORF">ESY86_19300</name>
        <name evidence="3" type="ORF">ESY86_19955</name>
        <name evidence="2" type="ORF">ESY86_20600</name>
    </gene>
    <organism evidence="4 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000091">
        <property type="protein sequence ID" value="TXD86114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="VORO01000053">
        <property type="protein sequence ID" value="TXD86526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="VORO01000039">
        <property type="protein sequence ID" value="TXD86757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="VORO01000034">
        <property type="protein sequence ID" value="TXD86932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13683">
        <property type="entry name" value="rve_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="2"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD86757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD86932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="52" mass="6174" checksum="0A9DBA56E07CA3F5" modified="2019-11-13" version="1" fragment="single">TNRYRFASSEQLHACLVEYISWYNTKRIHSTLGYRTPLEMQLELENLINKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDB6</accession>
    <name>A0A5C6ZDB6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">LamG domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_16130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000021">
        <property type="protein sequence ID" value="TXD87678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022877294" evidence="1">
        <location>
            <begin position="23"/>
            <end position="568"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="568" mass="61330" checksum="8273735B135131E8" modified="2019-11-13" version="1">MKNFKIYILGLCALLMFQSCYEGIDEISAVESGPDAGAPLITIMKPAEGLEIQVPELVTSTAIEFKVVDDIEIDDVTVFLDGNQIGYFDTFVDYRTANEAFVYNNITTGDHVLTVVAKDISGNSTTSTSNFTKSPPYTPIFAGEQFYMPFDGDFTELISITAATEVGNPGFAGSGYAGSNAYEAGTGNHLSFPLDDLTLGNNFSAAFWYKVNATPNRAGILVIGDDADDRFQGFRLFREASGDQQRIKLNVGTGAGESWNDGGLVDPASGDWAHVAFTISDTETKIYINGMEVNMAGMSAPVDWSGCNDIIIGAGGPTFSYWDHLSDSSAMDELRLFNTTLSQSEITQMVAQGSQIFQMSFNGSYAESYSDMEATTVGNPGFAGEAFAGTNAYAGAADSYLTFPTTGLLNSEFTASFRYKLDADPDRAGILVIGPTDTDNPDAQNKRTNGFRFFRENAGGMQRFKLNVGNGEGENWFDGGTAADVDPATNEWVHLAFTISDSECVVYINGDVAAQGAFPGVDWTDCDIMSIMSGAPRFTGWGHQSDLSYMDELRIFDKALTQEEIQSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDD2</accession>
    <name>A0A5C6ZDD2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Biotin--[acetyl-CoA-carboxylase] ligase</fullName>
            <ecNumber evidence="2">6.3.4.15</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.15" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004077">
        <property type="term" value="F:biotin-[acetyl-CoA-carboxylase] ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd16442">
        <property type="entry name" value="BPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004408">
        <property type="entry name" value="Biotin_CoA_COase_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03099">
        <property type="entry name" value="BPL_LplA_LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00121">
        <property type="entry name" value="birA_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="1">
        <location>
            <begin position="1"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="243" mass="27468" checksum="781A8EA85510D81E" modified="2019-11-13" version="1">MNIIKLDAIDSTNSYLRNLKTQESLENYTVVVAKKQSQGRGQMGTQWQSEASKNLTASIYAKVSYLEIHQAFYISMATSLALLKVLREFHLRQLYVKWPNDILADNLKIAGILIENSIKNTLMETTIIGIGLNVNQTQFGDLSQATSLKSITGVDHDLDQLLKRLAEQVVVEMKRLETGKLENVKKDYEAALFRKDKPSTFQTPDGHRFSGFIKGVSDVGLLQIRVEDNILKTFDLKDVKLLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDF4</accession>
    <name>A0A5C6ZDF4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mevalonate kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_14735</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001174">
        <property type="entry name" value="Galkinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00960">
        <property type="entry name" value="LMBPPROTEIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="SSF55060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="309" mass="34277" checksum="8D0E8CE29B228FCB" modified="2019-11-13" version="1">MKGPLFYSKILLFGEYGIIKDSKGLSIPYNFYNGALKSDGSTSEEAIKSNAGLSKYVAYLATIDTQLVQFDLEALTKDVEEGMYFDSSIPQGYGVGSSGALVAAIYDKYAKEKITVLENLTREKLLALKTIFAEMESFFHGKSSGLDPLNSYLSIPILINSPDHIEATGIPAQQTGGKGAVFLIDSGSIGETAPMVQIFMENMKQEGFRNMLKDQFIKHTDACVDDFLQGNIKSLFRNTKQLSKVVLNHFKPMIPAQFHELWKKGLDTNDYYLKLCGSGGGGYILGFTEDYKKAQQALKDYKLEVVYNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDS1</accession>
    <name>A0A5C6ZDS1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_17325</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000026">
        <property type="protein sequence ID" value="TXD87322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="142" mass="16710" checksum="2E2A5843869E681D" modified="2019-11-13" version="1">MILDSTHPNKEHKQIVTGLVGKPFTFFETFKRKGVGSKRMIVAEVSPNMQKYINRIDDLSYANIEMRTGGILMYINKGLKNYTWVIPYYQLVLYKTNGASIHAQGKFVHFRNSKTFKENKPFFDKLLDEKVKYDEQFNFRDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDT1</accession>
    <name>A0A5C6ZDT1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">1-acyl-sn-glycerol-3-phosphate acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000026">
        <property type="protein sequence ID" value="TXD87332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PlsC" evidence="1">
        <location>
            <begin position="53"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="266" mass="30981" checksum="2841AA339275BFBA" modified="2019-11-13" version="1">MALFKRNPFGHILFVKKWLIRILGVLTHQRFRGFNELQIEGSEIIKNLPENNVLFISNHQTYFADVIAMFHVFNASLSNRNDSIKNVGYLWKPKLNIYYIAAKETMKAGLLPKIMAYVGSISIERTWRSEGKDVNRQVKMSDISSIGKALDDGWVITFPQGTTTPFKPIRKGTAFIIKKYKPVVVPIVIDGFRRSFDKKGLRVKKKNIFQSMEIKAPLEIDYENESVESIIEKIEYAIEQHPSFLKVIPRKELEEKERLNKEFRDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDY5</accession>
    <name>A0A5C6ZDY5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="209" mass="22785" checksum="103063230392CB2F" modified="2019-11-13" version="1">MEWFSALDGFSQFFWIIALVGSVVFFFIIISTVMGMDSSEDFDSLDAEIDADVGIGFQFISFKNLIGFFTIFGWTGIGFYNAGLSKPLSVIAAFGCGLLMMAIMAGMFYAMGKLTNSGTLNYRNAINTIGEVYLTVGPNRTKMGKVTVNVQGSFRELEALSDSLMELKSGSIIKVVDVTNNGILIVEQTKKPIEPIKPETYELPPSSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEB7</accession>
    <name>A0A5C6ZEB7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">S41 family peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_12735</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the peptidase S41A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07560">
        <property type="entry name" value="Peptidase_S41_CPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004447">
        <property type="entry name" value="Peptidase_S41A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00245">
        <property type="entry name" value="TSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00225">
        <property type="entry name" value="prc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0720">Serine protease</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022710858" evidence="4">
        <location>
            <begin position="27"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="5">
        <location>
            <begin position="82"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD88379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="544" mass="61194" checksum="4A6C0E5CF55AAB91" modified="2019-11-13" version="1">MKTLLKKRVIVPILAICIFTTTSAFKGDFFEIAKQIEIFTTLFKELNMNYVDETNPGDLMDTAIKSMLNDLDPYTNYYNEQDVEKARINNAGDYTGIGANVLTLKDKLVIMEPYKGYAADKAGMKAGDEIIKVDNVAVGDFKEDAGNLLQGGAGTSVTVTYIRQGETKSTTIQREAVDIHAVPHYSMVNENIGYVVLRKFNEKTSSETISAIRALKNLGAKKLILDLRGNPGGLLSEAVNVTNIFVPKNQLVVTTKSKVEKYNKTYYTQKDPIDTEIPLVVLIDGRSASASEIVSGALQDLDRAVVVGARSFGKGLVQRPKKLVYGTQMKITISRYYTPSGRSIQALDYWNRDENGKATRIRQENYNEFKTKKGRIVFDGGGIQPDLELDETKLSPITKAIIEENLIFKYATDYYYNNEVSDLDSFELNAGDFKAFKSYLSKNDFDFETETEKAFADAFEIAKDEQIGSEINTDYNALITALNTYKDKAVDDNKAQLLSMITDEIVKRYFYREGLYTYYVAHNFEIQKAVEILKNPSNYLNYLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEC5</accession>
    <name>A0A5C6ZEC5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Flippase-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_13745</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022791">
        <property type="entry name" value="L-PG_synthase/AglD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03706">
        <property type="entry name" value="LPG_synthase_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00374">
        <property type="entry name" value="TIGR00374"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="160"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="211"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="240"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="266"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="296"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD88158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="317" mass="35608" checksum="CD07EF27764CD171" modified="2019-11-13" version="1">MNKSTAKFLKITLPLLLGVALVWYSLSKISTEELLRYFKNADYLYIIIGLICGLLSHLSRAYRWKFMIEPLGYTLRYANSIMAVFATYLVNYTIPRAGEITRATIITNYEGVPFEKTLGTIVAERIADMFVLLAIIALTLFLEFNFIYDFFMQRFDAYKLLIAILIFVCVAVGLFLFIKKSGSKLAIKIRAFVSGLIEGALAIFKMKKKWAFIAHTLFIWLMYVLMFYVTTFAIPETSNLPLAAILIGFISGSFSIAATNGGIGSYPVAIFAAFSIFGIAEEPAIAFGWIMWSSQTLMVIVLGGLSLIYLPIYNKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEC7</accession>
    <name>A0A5C6ZEC7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">NAD(P)/FAD-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_14720</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004792">
        <property type="entry name" value="BaiN-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023166">
        <property type="entry name" value="HI0933-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42887">
        <property type="entry name" value="PTHR42887"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00275">
        <property type="entry name" value="TIGR00275"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="402" mass="44811" checksum="0BCE80A2345B908A" modified="2019-11-13" version="1">MKHYDVIIIGGGAAGFFTAINLAERHPQLKVAILERGKTGLQKVKISGGGRCNVTHAEFIPSELVRNYPRGEKELLGPFHQFMTGDTIAWFEARGVSLKIEDDGRMFPVSDSSQTIIDCFLAEAQKHQVDLLYNHSVKTLQKTDGLWEMKTNTGLFSSEKVVLATGSNPKIWNLLESLGHAVAQPVPSLFTFDVKDERIKDIPGVVVQDVEVTLCDSGLTSEGPLLITHVGFSAASILKLSAFAALELAKHNYQFEIEINFIKQPFENCQLQLKQFKQDLAKKQVSKSAQLDIPKRLWKKLVLAADISEETRWADLNKQQLEHLAAQLTKAFFKVTGKSTFKEEFVTAGGVDLKEINFKTFESKLHENLYFAGEIMNIDAVTGGFNFQNAWSGGYIAAKHMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEE6</accession>
    <name>A0A5C6ZEE6_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5 7">50S ribosomal protein L3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplC</name>
        <name evidence="8" type="ORF">ESY86_14830</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 7">One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 7">Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uL3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01325_B">
        <property type="entry name" value="Ribosomal_L3_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000597">
        <property type="entry name" value="Ribosomal_L3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019927">
        <property type="entry name" value="Ribosomal_L3_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019926">
        <property type="entry name" value="Ribosomal_L3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11229">
        <property type="entry name" value="PTHR11229"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00297">
        <property type="entry name" value="Ribosomal_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03625">
        <property type="entry name" value="L3_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00474">
        <property type="entry name" value="RIBOSOMAL_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD87941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="205" mass="21920" checksum="1D7F1BD49F1DC32F" modified="2019-11-13" version="1">MSGLIGKKIGMTSIFDENGKNIPCTVIEAGPCVVTQVRTEEVDGYSALQLGFDDKTEKSATKAELGHAKKAGASVKRKVVEFQGFEGEFKLGDAITVDHFIEGEFVDIAGTSKGKGFQGVVKRHGFGGVGQATHGQHNRLRAPGSIGAASYPARVFKGMKMAGRMGGERVNVENLRVYKVVPEKNLLVVKGCVPGHNNSYVIIQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEH7</accession>
    <name>A0A5C6ZEH7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_16720</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000023">
        <property type="protein sequence ID" value="TXD87536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="437" mass="50597" checksum="2DDD1357B1EBC22F" modified="2019-11-13" version="1">MTEVIFCNSCGNGITINTSRCSCGNIMTFNEMKDLSEKFSKIEKYQLIKDSPASQVQLTQDELPLHSLSKKYFLGSSAKSDYEKKVSHIQKNLIPQITEWKEIVQNADEILAKDKVELYGKLLGITDFAIREFFGPFALKASNAEMFEEYRDFSKYELSKVMNDYSISLDDIQTTNFETIGIDVFNSINDTLHNGSFLELAEKDEFTDDDFRKVKGELGVAIAGELIKGIGNLIGENIDAIGNVREADSKLNEKLSHISKVIQSLSIEEQEINKRKTLFDKSDLIVETCYNKILKPIVDELKRDPIYLEYKLAREPYDLQQNKIEIENQALKIHSNISFWKALLNNSKKNFNHHLNKRLTIIDSLKEYDLLNKKLKDKRHKSLKAKNIYEEDKTELFREYELENRRILREVDVVKNNKKTVTEFFNVLKIVKENVIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZER6</accession>
    <name>A0A5C6ZER6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">LysM peptidoglycan-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_12350</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="SSF54106"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022755505" evidence="2">
        <location>
            <begin position="21"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="3">
        <location>
            <begin position="25"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="3">
        <location>
            <begin position="88"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="3">
        <location>
            <begin position="144"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="3">
        <location>
            <begin position="348"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="290"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="774" mass="85296" checksum="AD9080A33000BFD0" modified="2019-11-13" version="1">MWRFYWLLIIFILSFSLTNAQDNVIEHAIQKGETVYGISKTYGVSMEAIFALNPGSQEVIYAGESLRVPENGQTPNTPNTNPGTSNGSKYVVVRGDTKSGLSRKFGISIASLEQQNPQIVPMLMAGHVLNISKNFKVQINSKNGEHFVNKGETLWGIARANGISVNALIAANQDRLDGVLKAGQTLRIPEKNSAFSTGGDYIVKTGDTKWGLSKRFNLSIAQLEAKNPQIVPMLMAGHRLTLDADTEAPVETTARVSEVNEIETAPVAENEPEAIETTIPEIDTSLISDTGSASEENTSPPIIATEGNTSETEVSLPSEAEEVKNIDNNIEAFTETQNPDGASTAIYKDYVIQAKETLYGLSKKAGMSMEAFVALNPQLSNGVAKGAVIKMPINPGVFNNQDNETSTIVTSEIIRTNPNETLFRRLDKDKRTALFFGLQFALEDYENGSLAKNASDDAALQKHIDFYQGAEMAIDSARSLGLNFDVSFVERSASGKFSRLKVDNTSEENAVIVPFLKARETYPKVISKSPTAIIGLSSNSINSDSNTVYDALPSQLELKTRTLNYIAEKNAQIIVVSDLDEARNKDLILNIIPDAQFLKVDKTGFFVNNDLTAALHKEKLNYVILDTDRTIVFLNATTEFMGKLSEYDIEMVLIESASLPKPGQVSDMRFRILKLIFPSVMPIEKDEMLLQFEQAYKTRYDVEASENAILGFDTTFDVLLRLSQAAGFENSVETLKSQQLLLKFDYEKSNDTIFENKGLYLLQYGNGNQVIEID</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEU1</accession>
    <name>A0A5C6ZEU1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-glucosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_16125</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000021">
        <property type="protein sequence ID" value="TXD87677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019282">
        <property type="entry name" value="Glycoamylase-like_cons_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016883">
        <property type="entry name" value="UCP028431"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10091">
        <property type="entry name" value="Glycoamylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028431">
        <property type="entry name" value="UCP028431"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022712960" evidence="1">
        <location>
            <begin position="22"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="domain" description="Glycoamylase-like" evidence="2">
        <location>
            <begin position="226"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="465" mass="52878" checksum="89C30F457BDE3492" modified="2019-11-13" version="1">MLSTRLKITMLLLTVVFTAFSCKTDTKSKLADSQMENKGGTFDDLTSADMALLDTIQKQTFNYFWEGAEPNSGLARERFHTDDVYPTSPKNTVTIGGSGFGFMALLVGIERGFITREEGFARFQKMVNFLEKADRFHGAWPHWLNGETGKVLVFSKKDNGGDLVETSFLIAGMLSVAEYFKAGNTEEQALSQKINTLWQEVEWDWYTKGENVLYWHWSPNYKWEMNFPVGGYNECLIMYVLAAASPTHPIDRKVYTEGWARNDSIISSESMYGHDFILDYYEHAENQIGPLFWSHYSFTGLNPKGLSDTYANYWDLVQNHAMIHYDYAVDNPLNYKGYGKNIWGMTSSYSMNGYAGHHPGKGHDKGVISPTAALSSFPYTPKESMQMLKTLYKDHDSLIGKYGPYDAFSFEHQWFTPRYLAIDQGPIPVMIENYRSGLLWDLFMGNTDVQHGLDALGFSVSETND</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEW9</accession>
    <name>A0A5C6ZEW9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_15780</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="404" mass="48113" checksum="1AAC09FA4A5BC967" modified="2019-11-13" version="1">MIKNNIKILIIVLCITTCKKQEDINSRQLISDFNLESTYVNYRNGIKQTSNGYSKDSTLIFSLYENNKTSHFLYIVQNKKKDTIFKFFDSTAFELKIRNFDKINRNYFVTIWEPSPQKYIGYQTGYNIEYDLYQDLYTYDSLNIYLIDSTCSKLTKLSKPTNKNISNTFKTTFNLKGEFEVIKNDSEIRMVKDTLRNKKVLYQSNVGLEIDDNNNLKSHFFNKSKIKLDENNFSTMSDRFLISESLKGDINYYYKYDANYTNTGFSRIDFIFKQNNKEHIIQTTLDRLFIKDKEYKFKNIDSLSSLQIEPFKYKNGDYFFYVTQQSFEERSDNFPIIFYIDTINWEIERVKPHSIEASIKNKKLIEIYKTEILSNNHNSILKFILKDFEIARNNDGFELIKIKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF47</accession>
    <name>A0A5C6ZF47_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_11665</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023045038" evidence="1">
        <location>
            <begin position="23"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase" evidence="2">
        <location>
            <begin position="43"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="361" mass="40297" checksum="54F6D5135F86946F" modified="2019-11-13" version="1">MRHKPKLIPTILLFIFGALSFAQSTDEDIKAYLDALASDSFSGNILVAHNDSIIQQRAYGLSSIEYKVENTTNTTFNIASITKMFTAVATLQLYEQGKLELHIPIDAYLPDYPNKLVRESISIHQLLTHTSGLNNFYVDDLDKLKPSAYKNISDFVPLFVNDTLLSKPGTQYHYSATGFVILGLIIEKVSGTNYYDYVKENIFKPANMPNTAALAMDAIVVNKASGYTSMFGENTVLKKNDTYLTKASPAGFYYSTLSDVFHFSKALRNHNLLSEATTELMFKPKVKGYNTHLGYGIDVDQRYNQTILGHSGGWYGIHCELMDFMDDHYTVVILSNIDDGGKTGASKVADFFKALIAEKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF87</accession>
    <name>A0A5C6ZF87_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_15460</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="61" mass="6767" checksum="282DD9B36A8E0150" modified="2019-11-13" version="1">MATVDNIRNGLIDKILSIKNKDFLQALDNLITSSSSSSELVELTNEQKVMLEISEEDIKNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFG4</accession>
    <name>A0A5C6ZFG4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2279 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11065</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018736">
        <property type="entry name" value="DUF2279_periplasmic_lipo"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10043">
        <property type="entry name" value="DUF2279"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022947648" evidence="1">
        <location>
            <begin position="21"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="303" mass="34180" checksum="ABA93E67DDAEEE09" modified="2019-11-13" version="1">MKKGLVYVMLIALASLSAHSQSRFESFLKPSDSLDTSRRNAVVISEATLASITLIGLNQLWYADYPQSSFKTIDDADEWLQMDKLGHVFSAYQLGKTGANVLNWSGVSKRDQLIYGATLGFGFLTAVEVFDGFSEEWGFSWSDMAANATGTGLYVGQELLWKEQRINLKYSFHQTDFAKQRPDKLGDGLLEELLKDYNGQTYWLSANVHSFFKTSKIPKWINVAIGYGAEGMLTGTNETQTGVFAQQNRQRQFYLSLDVDLTRIKTNSYILKTLFDVFNLIKVPFPTLEFNGKNGIKLHAVYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFN5</accession>
    <name>A0A5C6ZFN5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glycoside hydrolase family 31 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_12840</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032513">
        <property type="entry name" value="AGL_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033403">
        <property type="entry name" value="DUF5110"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025887">
        <property type="entry name" value="Glyco_hydro_31_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16338">
        <property type="entry name" value="DUF4968"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17137">
        <property type="entry name" value="DUF5110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13802">
        <property type="entry name" value="Gal_mutarotas_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022945255" evidence="3">
        <location>
            <begin position="22"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4968" evidence="5">
        <location>
            <begin position="32"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="Gal_mutarotas_2" evidence="4">
        <location>
            <begin position="147"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5110" evidence="6">
        <location>
            <begin position="697"/>
            <end position="766"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD88400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="827" mass="95214" checksum="B502BCB75BE75F5E" modified="2019-11-13" version="1">MNKIYSLILMFFIFSFSWSQDQLNVIDAITHKNKVVFTCENKSKISLEFLDSKNIKFWFSPNGEFVRNNESFAVINAVFDENYTINVNESSSVYEVFTEDLRVMVHKSPFKIQIFNKYQRLILGDTVEQPYVVDGTDIKTSKVLRQDEHFFGLGEKTGTLDRRGKSYTMWNSDKPCYSEKEDPLYKSIPFFMSSYNYGIFFDNTYKTQFDFGKDSTDSFSFSSPDGPFIYYFFYGKDYKEIIKSYTKLTGKPIMPPKWAFGWAQSRGLLTNETLTRDIAQEYRERNIPCDIIYQDIGWVEGLQNFEWAKEKYKNPKKMLSDLADTGFKVIVSQDPVVSQATTKQWEEADAKGLFATDIRTGESYDMPWPWGGNAGVVDFTNPKTAAWWGDLQQIPINDGVKGFWTDMGEPAWSNEESTDRLNMKHHLGMHDEIHNVYGLTWDKVVTEQFEKHNPNQRVFQMTRAAYSGIQRYAFGWSGDSGNGEDVTDGWANLANQIPLGLSAGLGLIPFWTTDISGYCGEITDYPEFAELYVRWLQFGIFNPLSRAHHEGNNAVEPWLFGKQAEKIAKASIELKYQLQPYLYSYARQSYDTGIPIMRALVLEYPKDENTFNIDDQFMFGEYLLIAPVVEEGAKTRSVYLPKGEWIDYNNPATTYNGGTTIKYPVTLETIPMFVKAGSIIPKSPIVPYTGALKNAPVILEIFPSNNMNSFELYEDDGETNNYKNDEFALTKIEAENAPSILKVDIDVPQQNEFKTEIRNYLLKIHTTSKPKRVEINSNQIKPVSPSKISENLNTNFKESNYFFDEKNQLLMIRLPDTKLRTEITIFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFT3</accession>
    <name>A0A5C6ZFT3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_16045</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000021">
        <property type="protein sequence ID" value="TXD87685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006103">
        <property type="entry name" value="Glyco_hydro_2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02836">
        <property type="entry name" value="Glyco_hydro_2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_2_C" evidence="1">
        <location>
            <begin position="67"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1046" mass="117525" checksum="91439FE75DB30C29" modified="2019-11-13" version="1">MIFLFSATVFAQADMVCVSNDQDGMILVVNGEEFIINGMNWDYIPIGTNTVDANFWKKSDEIIKAGLDSEMSLLKNMGVNVIRQYTGVPARWIEYIYKNYGIYTMLNHSFGRYGLTLDGVWTPVTIYDDKATQEHLMDEVTNLVNDYKDTPGLLLYLLGNENNYGLFWQGAETEDFPDDEEEKNFIGEKRGRPMYKLMNDAAKAMKSIDTSHPVAICNGDVLFIDIVAEECEDVDIYGTNTYRGASFTDMFDVVKEKLDMPLLFTEFGADAFNAKENREDQKAQAYYMVENWKEIYQHAAGLGKTGISIGGFTFQFSDGWWKYGFDDRENADVHDNNASWTNGGYDIDLAPGQNNMNEEWFGICAKGPTNERGLYELYPRAAYYALKEAHKLNPYDENMTGDFVTNYFNNIQLMDAVLKARGDKAALGGNDQKIRLSQLTARFTTFSTGGSLITTPENPEPDGNVFPNQLGFDNMQSYFIGVEGNPAPNVRAEVNFNVVGNVAQNPIDEIFYENRSRPLTVNSDDGDVILGDINKINVYQAEFEWNAKDFDLRGFYRTGHYHWGYEGDFFGLYPEANYGPNLDIYGGEILGLEIDGKGAAKGLKAAFGPQLWWGANPTMLFKYQKKLGNYALTGIYNRDVETQLQIDANGRRILDQNQVRSGIIPAYPTERATIAVEREIGKFGLTLGGIWSGKPLNGSSFQNVKDGVVYVDKVESNDNWGGKAKITYEGGKFNWYAQGAIMGLVANGGADATQTFTGWRLKDSGSGNLNNFLTGFTYSFSNFQIAPNFMWQAPLVDPMPNGVNAPGRLRNVIDDPFAVRGGNRETTAGEILFTFDPTPGTWMYQWDNDRAEDAEFAMNLGFVFRHLPTTQDGAIGFLANRTFFAFANSAPAEDLWEIHSRMVSKLTPDLGIIGNFYYGNGQANGDSQRLIRRFGGDVRAIYKKMKVETHVKINDWGPFDYHRDFNLTFPLQLMFDFSTSLGKPDWFVLPSTTIGLRGTWRSLNEFSPRYSPTLAPEFGVPPLSPVGFPNGDEWEIRTYVHINIGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG14</accession>
    <name>A0A5C6ZG14_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">MerR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_12575</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="96" mass="11665" checksum="37A4805299097DA3" modified="2019-11-13" version="1">MKDTHLIPIPELCTHYHLELSFFDELKNYGLIEITTVEQVYCIHKDRMPELEKMIRLHRELNLNFEGIDTVFNMLEKMERLQVELTTVKNRLRLYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGE5</accession>
    <name>A0A5C6ZGE5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Fic family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_09940</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003812">
        <property type="entry name" value="Fido"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036597">
        <property type="entry name" value="Fido-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040198">
        <property type="entry name" value="Fido_containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13504">
        <property type="entry name" value="PTHR13504"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02661">
        <property type="entry name" value="Fic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140931">
        <property type="entry name" value="SSF140931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51459">
        <property type="entry name" value="FIDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fido" evidence="4">
        <location>
            <begin position="97"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="176"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="180"/>
            <end position="187"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="217"/>
            <end position="218"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for autoinhibition of adenylyltransferase activity" evidence="3">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD89158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="325" mass="37546" checksum="6EFC8B80EF51D6D9" modified="2019-11-13" version="1">MKPPYEITPEILKCITSISEKVGEINANYLNRPSPKLRKQNKIKTIHASLKIEGNSLTEEQVTALIENKRVIGPEKDILEVLNAIEIYENLGHYNPNNEKSFLKAHQNLMKLLIEASGRYRKQSVGIVKGSKVQHLAPPFKNVSFLMKDLFEYLKDSEEIVLIKSCVFHYEMEFIHPFMDGNGRMGRLWQTLILMQKYPVFEFLPFETMISNDQEKYYSALALSDKAGQSTKFIEYMLNVIDASLNKLLDFNNRTLNEQERLGYFISLNKIEFSRKEYMDVFKNISSSTASRDLKKGLESNLFEKMGEKSKTKYKLIGGKNITIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGH8</accession>
    <name>A0A5C6ZGH8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SusF/SusE family outer membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_12820</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001070">
        <property type="term" value="F:starch binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025970">
        <property type="entry name" value="SusE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032187">
        <property type="entry name" value="SusF/SusE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14292">
        <property type="entry name" value="SusE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16411">
        <property type="entry name" value="SusF_SusE"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022911347" evidence="1">
        <location>
            <begin position="25"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="domain" description="SusE" evidence="2">
        <location>
            <begin position="34"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="501" mass="55509" checksum="571F158635336386" modified="2019-11-13" version="1">MMRTHIKVKFVSVIFLTVIFSAFMSCDDELTNDAFDQEDTLALSISNEDLVLEELFFTNKVNFNWTTGTNQDTGAAITYTLEMDMASGDFTTPLATLFSGVQATYRYEMTYGDLNNLLLDSGLNPNESHQLSVKVTATIADASVAEQTAVTNFTVTTFKPISSRLFMVGDATPNGWDLTNATEMVPSTNTRGVFTYEGGLIPGNFKFAVNQDGCFCQDFYTKDATDDTLMVYNEGGSGDDLQWTIDQALEPNENYRITADVLNLTIIIEVVESSVDTPPFSTLWIVGDATESGWNIDAPIAFNQDEENAFLFYYEGQFNSGNFKIFAGPLGDFCGQWYRPFTNNEVMENGPVNQNSGCDSDNNWLVTEQIKGRYKVVLDTQNNTVSFNKIALYIIGDGGPNGWNISTPAPMTYSDGEYVYTGPLGANNPTGEFKISKFKGDWCNGDWINPATNGQSITNTNFINTYDCDGPDNKWKLQTGQAGNYEIRINLETDQMTITAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGI1</accession>
    <name>A0A5C6ZGI1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF3857 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_11105</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024618">
        <property type="entry name" value="DUF3857"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12969">
        <property type="entry name" value="DUF3857"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023024348" evidence="2">
        <location>
            <begin position="20"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3857" evidence="3">
        <location>
            <begin position="72"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="526"/>
            <end position="553"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="723" mass="84428" checksum="8D329E7707D331CB" modified="2019-11-13" version="1">MTKKLLALLLLFQSLSVLSQSKEALEAKNFFWGEADKSRTVSDIPANLQNESAVILYKNENYDFHKYGKNVTYTSSIRKRIKLLDQAAVDEFSEFSFQERFYSSKGQFNWFRKGSTTVGIKIIKPDGSETEIDVEAEAIEVDGENKLAIANLEVGDIIDYYYFTKEPFKSTYAFGFEPVEKPLAEEYPILEYKLFFETENDFFINFNSYNGAPKLSEIPTEKRNMRRYELTEINIPKGDFTRWFYPLVELPSYKFQVYFARSGKFEDLALAFLPKNEATIKTSVSQQEVLELYENRFRPDGDLGDVKDYFKGKTFEDDAHKVTAAYYYMRHYYLTRFMEAFYAKDANISPYPFMVYGNNVVFIQSQKQFIRHFTEYLRRQKIAYEIVVAKNRFDGTLDDLLIENNIEILVKINTEKPLYASFFGPHTNINEFSPLLEGTEVYLLSASRYRIDQINKGKLPSSTYADNETKKNITLSLNEAMDGFKLTAVNSYKGHEKSDQQYDRFLYTDYVSEDYKKYETETWVDMVRREKDQEKYQKELDALTEKLRSTQKERFEDSAKAEYFADALEDYTYQINANGRYSLDSYFIFTEGFTTKNTLIKKAGPNHIIEIGKLIGGQIDLTKKERERSENIYLPYPRSYNYQINMKIPDGYSVSGLEKLNTSVDNATGAFISTAKIEDGVLIINTFKRYKNYFEPNSNWEQMIAFLDAANQFTNEKILLKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGK3</accession>
    <name>A0A5C6ZGK3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Rrf2 family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_11255</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000944">
        <property type="entry name" value="Tscrpt_reg_Rrf2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33221">
        <property type="entry name" value="PTHR33221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02082">
        <property type="entry name" value="Rrf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00738">
        <property type="entry name" value="rrf2_super"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51197">
        <property type="entry name" value="HTH_RRF2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="144" mass="15931" checksum="265E343891CCA934" modified="2019-11-13" version="1">MFSKACEYGIKASIFIAINSYNDNRVSPKEISAEINSPQAFTAKILQALVKHNIVNSVKGAYGGFEINKEDIAKIKLSQIVTAIDGDQLLHGCGLGFKVCDEEHPCSLHDQFVFIRNDLRNMLENTTLELLAKDIKSGVSFLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGN1</accession>
    <name>A0A5C6ZGN1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_09855</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="197"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="380" mass="43276" checksum="2658DAAF14EE3EE8" modified="2019-11-13" version="1">MHRKKILITIDWFLPGTKSGGPVRSYANLIEHLNEGFEFYIVTRNTDFGSTESYESITPNVWTRFNAYTQVFYCSADYLSKTHLKTLFETTEFDFAYINGIYSWYFSILPVMLLKKSNKPIIVSARGMLNPQAFSVKPFKKKLFINIAKGFRFYTKIQFHATNTEEAIYIKQIIGSSTNVKVAPNLPRAVNTSAKPKVSKQHPVRFVNLARVSIEKGTLTMLNALRHVKASLILDLFGPIYDTAYWEKCQTVIAALPDSIEVNYKGVLDSEEVPELLRGYDFFVLLSEGENFGHAILEALSAGIPVLISDQTPWRNLTSQSVGWDLNLNDEETIIRAFETAITMNDENYTKWSQAAFHYAKEVIENPKVLEQNKALFLNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGT6</accession>
    <name>A0A5C6ZGT6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10255</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="219"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="268"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="301" mass="34890" checksum="105109F16AAEB77E" modified="2019-11-13" version="1">MTKTKNIISALFNSLLSEHTREKVENVILYIALASFFIHLAAIYLLKFDIINLPFDSELLKSPISAVYTPFSFILIYEVYLLIYYLPKSFTTYITKQYEIITLIIIRKLFKDLSALELTENWFEIKGDLQFTYDIVASLLLFYLIYLFQKQGQQKAVQEADNKPFIETFVKKKKLIAVILVPLFFFMALYTLIDWYIGISLSANELEPFESINNLFFDEFFTILILVDVVLLLISFFYTNQFHKIIRNSGFVISTILIRMSFSVSGLISTILIVVAVLFGLAIIAIHNKYEKNALPSKEMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGW4</accession>
    <name>A0A5C6ZGW4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fasciclin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_09045</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02469">
        <property type="entry name" value="Fasciclin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00554">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="SSF82153"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50213">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022869943" evidence="1">
        <location>
            <begin position="23"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="2">
        <location>
            <begin position="33"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="2">
        <location>
            <begin position="181"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="333" mass="34709" checksum="120CC0EFAE8D14EA" modified="2019-11-13" version="1">MKNLYTLKYALMSVLAISLLYACESNSSYEDEAPSIANIAVSNPNFSTLEAAAVLGNVAVTLSNSNPNDPSGDYTVFAPTNDAFGRLGLNENTLGVLQPAFLTNTLLYHVSNGNLRSDAIMDGVASTSAIGVDRRFVSRDGDLYINGSKILATDIMASNGTVHAIDKVMIATGVDIVQSAIALQSANVFTTPELSYLVEAVVYTNLVGALSASEGSPSFTVFAPSDQAFIDLGAALGLTFNEPADIRQLPVDVVTTVLLNHVVANNGKFTCEMNQGSITPLGGDALTLGAFENGTITVSGAGSGGEVANMLIPDVQTTNGIVHVIDRVLLPNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH40</accession>
    <name>A0A5C6ZH40_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uracil-DNA glycosylase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_12255</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="SSF52141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="226" mass="26238" checksum="722A4D12F7F6E873" modified="2019-11-13" version="1">MFFHKHPYSPFIQLDSKKLIVGTLPPPRFTTGDLLEKDVDFCYGSCYNSLWLFIDEIYELDLRYDNSDTAVQQRKQFLVKHKIGVCDIVESAEREKIDASDLGMNNIALRDIMAYLKKFPNIETLIFTGGNSKNGPEYFFRKHLKTYDLKLRLVSNEVPRIHEFIMPAQNLSNPTQLRTIKTVSLSSSSGAANISISRMPLYKQLKAKNPDFNTFDFRVMQYREFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH47</accession>
    <name>A0A5C6ZH47_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cystathionine beta-synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11570</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="614" mass="68909" checksum="B9DEBBB8BFCEACB1" modified="2019-11-13" version="1">MKETKMLDYIKEVLENMPKDWVNLTTHRLDLYDEKLAKVQFLEQFENLFKDNNYQASALRDLPTAYDYIRLGHPLSSLLEWGIAQLHELDANNVISFSSQTMPVLAILRKNHLEHKKTQIIHTGFLPDYFDAEIIRRVYGYDFELKQAESAEDILEFNGSSIFMSQQHKIGALNLNPNIDFFINLHSHLGSVLVINGKENEAYVSDIQHVRRRETIAMTPVNSLKALHSLINQSSFEDKKSDFETDKIAVLEAIKKITGTSTKPLVASSGLSMQYAVMMGLIHDALDKHPGKAIKFLVPPNCYGGTNDQARRVAACLDNVEVVDLPVDGDNDMVKSIDTVLANIAKQDAIPYIIAEIPTNPRVEVPDLLQLKAVLSKERTTSNGESAIDPVFILDQTFCPNVHFLGEGEILSTVRTISYASGSKFPSGGQCTAGYCAGNTKTEGLMEKIEMHLQLCDNEATDSQMEILARQMPSMNQRIHDAYKNTREFVSFIEDVLPEAKINFVSEELAAQGFTPSVFSLDLPTKGNTAEEKEAHKRELNLKLINLMITEIPNESKFCVSYGQLKGCYWTIPATSTQGTTKEGDKDYIVRTSVSPNIDLKLHKKVFMDFVESI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHA4</accession>
    <name>A0A5C6ZHA4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Xanthine dehydrogenase family protein subunit M</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_13245</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005107">
        <property type="entry name" value="CO_DH_flav_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036683">
        <property type="entry name" value="CO_DH_flav_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002346">
        <property type="entry name" value="Mopterin_DH_FAD-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03450">
        <property type="entry name" value="CO_deh_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00941">
        <property type="entry name" value="FAD_binding_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01092">
        <property type="entry name" value="CO_deh_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55447">
        <property type="entry name" value="SSF55447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="339" mass="37036" checksum="4F4737AA96ED3626" modified="2019-11-13" version="1">MNNFTYQKVSNPNDALNKISKNNAANFIAGGTNLIDLWKYNLAHPKTLVDINGLNDYKAIKEDDHGGLFLGALATNSDTAYHKLVEERYPLLSKAILAGASAQIRNSASNGGNLLQRTRCYYFYDASSPCNKRNPGSGCPAKNGLNRIHAILGTSEDCIAVFPSDMCIALAALEAVVHVKSPDGEREIEFSNFHRLPGDTPELDNNLKENELITGISLPSEGFAENYSYLKLRDRNSYAFALVSVATGMVLENNKITKIRIALGGIAHKPWRVVAAEEFLVDKSPTEENFASAANMILKGAKGFGKNDFKIELSKRAIVRNCIMALDPESQRPGAQPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHG2</accession>
    <name>A0A5C6ZHG2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">M48 family metallopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_10340</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase M48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022690784" evidence="7">
        <location>
            <begin position="21"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M48" evidence="8">
        <location>
            <begin position="93"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD89156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="276" mass="29866" checksum="BD9720B20D777905" modified="2019-11-13" version="1">MNMKNNIVATVTLALFLSCATNPFTGSKTLALVPNDSLFPSAFAQYNQFLTESKVIKGTANAEMITRVGQRIAVAAERYLNANGYQGYLEDYRWEYNLVDDNTVNAWCMPGGKIVFYSGILPVAENETAIAAIMGHEVAHALANHGQQRMSAAYIQQGVAVAGNIALANDENLALYNQAFGIASNVGVMLPFSRDHETEADKIGLYLMAIAGYDPDEAAELWKRMDAKSSGQAPPEFLSTHPANATRISNLQSLASKAVAEAKKFGVTSFRPLGKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHI3</accession>
    <name>A0A5C6ZHI3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Mechanosensitive ion channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_14595</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045275">
        <property type="entry name" value="MscS_archaea/bacteria_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011066">
        <property type="entry name" value="MscS_channel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011014">
        <property type="entry name" value="MscS_channel_TM-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008910">
        <property type="entry name" value="TM_helix"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30221">
        <property type="entry name" value="PTHR30221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05552">
        <property type="entry name" value="TM_helix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82689">
        <property type="entry name" value="SSF82689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82861">
        <property type="entry name" value="SSF82861"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="86"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD88110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="274" mass="30643" checksum="25F6AD7211BEB2F0" modified="2019-11-13" version="1">MELERWINKGYELLIEYGPKVIAAILIWIIGSWIARMLIKGIRKTMESRDFDISLRKFLLNLLSAAFKIVLIVVVLGTVGVETTSFVAILAAGGLALGLALQGTLANFAGGVLIMLIKPFQIGDWIKAQGIEGTVKEISIFNTRLTTFGNQSAIMPNGKLSNDNIINYTREGIRKESLTFGISYDSDIKLTKDILLKLVNEQPTVMHEEGKEPMIVVAELADSSVNLSLRYWAKNEDFWALRWTVLEDGKMRLEAEGIVIPFPQTDVHLFKEEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHK3</accession>
    <name>A0A5C6ZHK3_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Site-specific DNA-methyltransferase (adenine-specific)</fullName>
            <ecNumber evidence="2">2.1.1.72</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_07420</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:15197"/>
            <dbReference type="Rhea" id="RHEA-COMP:12418"/>
            <dbReference type="Rhea" id="RHEA-COMP:12419"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90615"/>
            <dbReference type="ChEBI" id="CHEBI:90616"/>
            <dbReference type="EC" id="2.1.1.72"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.72" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022749">
        <property type="entry name" value="D12N6_MeTrfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003356">
        <property type="entry name" value="DNA_methylase_A-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038333">
        <property type="entry name" value="T1MK-like_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12161">
        <property type="entry name" value="HsdM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02384">
        <property type="entry name" value="N6_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HsdM_N" evidence="4">
        <location>
            <begin position="11"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="N6_Mtase" evidence="3">
        <location>
            <begin position="147"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD89608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="520" mass="58760" checksum="83715CEDCAF5CB62" modified="2019-11-13" version="1">MSTNKLTLETLESWLWDSANILRGSIDSSDFKNYIFGLLFLKRSNDVFEEEVEQIMKRDKVSREIAEDDTYFQLPPESRWESIKKHTENIGIALDKAFAAMERENTSLEGVMTATKFGDKEKLSDELLQRLLRHFNQHSLRNDHLESNDLLGDAYEYLIKMFADDAGKKGGEFYTPRGVVQLIVQLIKPEPKQKVYDPTCGSGGMLIESARYIAEQPNGKVGNNINVSLFGQEKNLGTWAIGKLNMLLHNFMDADIRKGDTLINPQHKNDNNELTLFDRVIANPPFSQNGWWTPAENSIEVKLDKNGKEKKVSPNYNKVVSDPYGRFQFGIPPRGYADLAFLQHMIAVLKQDGKAGVVLPHGTLFRSGSEGKIRQGLLEADLVEGIVGLPSALFYNTGIPASIWIINKNKTEVQKGKVTIIDASSDYKEGKNQNELLEAHVAKIVNAYDDSTDVDKYMRIVDLKEIADNDYNLNISRFIDTSEPEVEVDIIAVHQKLEVLEQKEAEIDKKLAEFLKELGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHM8</accession>
    <name>A0A5C6ZHM8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF2461 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_10535</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012808">
        <property type="entry name" value="CHP02453"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015996">
        <property type="entry name" value="UCP028451"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36452">
        <property type="entry name" value="PTHR36452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09365">
        <property type="entry name" value="DUF2461"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028451">
        <property type="entry name" value="UCP028451"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02453">
        <property type="entry name" value="TIGR02453"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="226" mass="26984" checksum="47CD3253A89C0383" modified="2019-11-13" version="1">MTPLAFTKDQLHFLEQLRKNNDRDWFDKNKTEFKSHEARAKKSFQTIFENLKVHDLVEDFKVFRIYRDVRFSKNKLPYKTHFSASFIRRKPELRGSYYLHIQPNDQSFIATGFWEPNKEDLLRLRKEFEQDDTELRAILNSKGLKNIWGELKGDELKTAPRNFDKEHPAIDLIRKKQFIFTKSFSDQEVLSDLFIENVNTAFKAIRPYFDYMSDVLNTNLNGESTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIG0</accession>
    <name>A0A5C6ZIG0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DUF202 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_12955</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003807">
        <property type="entry name" value="DUF202"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02656">
        <property type="entry name" value="DUF202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="DUF202" evidence="6">
        <location>
            <begin position="26"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD88461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="106" mass="12590" checksum="BEA923BC5AF9BB85" modified="2019-11-13" version="1">MRLLRFGRDFKPDEEVILRDYLAIERTRLANERTLLSYIRSSLYLLLGGIGLFQLKDFADFKFLAFLSLGFSAIFFLIGVYRFTLLKKSLKRLYYISEDKEKTEQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIG3</accession>
    <name>A0A5C6ZIG3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF3108 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08605</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021457">
        <property type="entry name" value="DUF3108"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11306">
        <property type="entry name" value="DUF3108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022781745" evidence="1">
        <location>
            <begin position="19"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="259" mass="30047" checksum="38813E58CE5DDB7D" modified="2019-11-13" version="1">MKKTLLILTLIFGLHSVAAQKKSAYQDGEWFKFDMSYSNFLTAGTATLEVDETTLNGKPVYHIVGKGWTTGAIKWFFKVKDRYESYIDKDTGMPYKFIRKIDEGGHTKDLEIDFDHIKKEAFIENKKHKTTKRVSIEQDVQDMVSAFYYLRNNYETESIKDGEVVELNMFFDEENYIFKLKYLGRETIDTAFGRVKTLKFRPYVMAGRVFKEQESLTLWVSADDNKIPLKIKADLAVGSLQANLEAFKGLKHSFKVQFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIJ9</accession>
    <name>A0A5C6ZIJ9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Thiamine-phosphate synthase</fullName>
            <shortName evidence="8">TP synthase</shortName>
            <shortName evidence="8">TPS</shortName>
            <ecNumber evidence="8">2.5.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Thiamine-phosphate pyrophosphorylase</fullName>
            <shortName evidence="8">TMP pyrophosphorylase</shortName>
            <shortName evidence="8">TMP-PPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 12" type="primary">thiE</name>
        <name evidence="12" type="ORF">ESY86_10670</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8 9">
            <text>2-(2-carboxy-4-methylthiazol-5-yl)ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H(+) = CO2 + diphosphate + thiamine phosphate</text>
            <dbReference type="Rhea" id="RHEA:47848"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:62890"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 8 9">
            <text>2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate + 4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 2 H(+) = CO2 + diphosphate + thiamine phosphate</text>
            <dbReference type="Rhea" id="RHEA:47844"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:62899"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 8 9">
            <text>4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine + 4-methyl-5-(2-phosphooxyethyl)-thiazole + H(+) = diphosphate + thiamine phosphate</text>
            <dbReference type="Rhea" id="RHEA:22328"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
            <dbReference type="ChEBI" id="CHEBI:58296"/>
            <dbReference type="EC" id="2.5.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 8 10">Cofactor biosynthesis; thiamine diphosphate biosynthesis; thiamine phosphate from 4-amino-2-methyl-5-diphosphomethylpyrimidine and 4-methyl-5-(2-phosphoethyl)-thiazole: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the thiamine-phosphate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.3" evidence="8"/>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD89010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00060">
        <property type="reaction ID" value="UER00141"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004789">
        <property type="term" value="F:thiamine-phosphate diphosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00564">
        <property type="entry name" value="TMP_TenI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00097">
        <property type="entry name" value="TMP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036206">
        <property type="entry name" value="ThiamineP_synth_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022998">
        <property type="entry name" value="ThiamineP_synth_TenI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034291">
        <property type="entry name" value="TMP_synthase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02581">
        <property type="entry name" value="TMP-TENI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51391">
        <property type="entry name" value="SSF51391"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00693">
        <property type="entry name" value="thiE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8 9" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="5 8 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TMP-TENI" evidence="11">
        <location>
            <begin position="15"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="HMP-PP binding" evidence="8">
        <location>
            <begin position="34"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="THZ-P binding" evidence="8">
        <location>
            <begin position="131"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine</name>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine</name>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>4-amino-2-methyl-5-(diphosphooxymethyl)pyrimidine</name>
            <dbReference type="ChEBI" id="CHEBI:57841"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>2-[(2R,5Z)-2-carboxy-4-methylthiazol-5(2H)-ylidene]ethyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:62899"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TXD89010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="214" mass="23375" checksum="064EFFF426340E22" modified="2019-11-13" version="1">MTIPKLHYISQGSTPKEHLEHIQKACSSGAELVQLRLKHVSEKKTLKLAEAAREITSHFQTRLIINDHYKIAKTVKADGVHLGKTDASPTLVGKHLHTWQMIGGTANTLQDCETLIGKDVDYISLGPFRFTTTKGDLAPVLGLNGYTAIMEALKTETPIIAVGGISTDDVKDLLETGISGIAVSGAITRDFNSIRLFNQLLNASSTEEKRHTFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIQ2</accession>
    <name>A0A5C6ZIQ2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Exodeoxyribonuclease III</fullName>
            <ecNumber evidence="4">3.1.11.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">xth</name>
        <name evidence="4" type="ORF">ESY86_08420</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA repair enzymes AP/ExoA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.11.2" evidence="4"/>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008853">
        <property type="term" value="F:exodeoxyribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004808">
        <property type="entry name" value="AP_endonuc_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020847">
        <property type="entry name" value="AP_endonuclease_F1_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020848">
        <property type="entry name" value="AP_endonuclease_F1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22748">
        <property type="entry name" value="PTHR22748"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00633">
        <property type="entry name" value="xth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00726">
        <property type="entry name" value="AP_NUCLEASE_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00727">
        <property type="entry name" value="AP_NUCLEASE_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51435">
        <property type="entry name" value="AP_NUCLEASE_F1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endo/exonuclease/phosphatase" evidence="3">
        <location>
            <begin position="5"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="254" mass="28918" checksum="4B9FE6A52418C9BF" modified="2019-11-13" version="1">MKIISYNVNGIRAAMRKGLVDWLQSVNADVVCLQEIKANEDQVEIDAIEAAGYKYNYWFSAQKKGYSGVAILSKIKPNHVAYGTGIASMDFEGRNIRADFDGVSVMSLYLPSGTNDARLDHKLDYMALFQDYIDELKIELPNLLICGDYNICHEAIDIHNPVGLKNTSGFLPVEREWIGSFLENGFIDSFRQFNQEPHNYTWWSYRANARANNKGWRLDYGLVTEPLQEKLKRSVILSDAVHSDHCPILVELEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIQ7</accession>
    <name>A0A5C6ZIQ7_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">Delta-aminolevulinic acid dehydratase</fullName>
            <ecNumber evidence="4 11">4.2.1.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">hemB</name>
        <name evidence="13" type="ORF">ESY86_07520</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>2 5-aminolevulinate = H(+) + 2 H2O + porphobilinogen</text>
            <dbReference type="Rhea" id="RHEA:24064"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58126"/>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <dbReference type="EC" id="4.2.1.24"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homooctamer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the ALAD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.24" evidence="4 11"/>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00318"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004655">
        <property type="term" value="F:porphobilinogen synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001731">
        <property type="entry name" value="ALAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030656">
        <property type="entry name" value="ALAD_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11458">
        <property type="entry name" value="PTHR11458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00490">
        <property type="entry name" value="ALAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001415">
        <property type="entry name" value="Porphbilin_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00144">
        <property type="entry name" value="DALDHYDRTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01004">
        <property type="entry name" value="ALAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00169">
        <property type="entry name" value="D_ALA_DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="7 11 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 11" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="9">
        <location>
            <position position="196"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="9">
        <location>
            <position position="254"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001415-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001415-5"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TXD89626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="330" mass="36838" checksum="ADF2D7232F215B1D" modified="2019-11-13" version="1">MYPLIRNRRLRTNESIRSLVRETVLSPNDFLVPIFVVEGKNIKDEIASMPNYFRYSLDLLEKEVKELWSLGLKSVLLFVKVEDKLKDNTGKETYNPDGLMQRAIKTVKHACPDMLVMTDVAFDPYSAYGHDGIVQNGRVRNDESVEVLAKMSLSHAQAGADFLAPSDMMDGRILAIREILEGSGYTDTGIMSYSAKYASAFYGPFRDALDSAPVDAQDIPKDKKTYQMDFANRSEAIKETEMDINEGADIVMVKPGLCYLDIVRDIKNTFNVPVAVYQVSGEYAMVKAAAEKGWLDHDAVMLEQITAIKRAGADVIASYFAKDVVKLLGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIV8</accession>
    <name>A0A5C6ZIV8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_07860</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial sugar transferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003362">
        <property type="entry name" value="Bact_transf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017475">
        <property type="entry name" value="EPS_sugar_tfrase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02397">
        <property type="entry name" value="Bac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03025">
        <property type="entry name" value="EPS_sugtrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="71"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="266"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="Bac_transf" evidence="8">
        <location>
            <begin position="261"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD89686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="452" mass="53276" checksum="5952769F4902F55D" modified="2019-11-13" version="1">MSLFKQGRYSGYLRPISYLIDLSILNGFAILYFFKTIDPVVFIAFASISWIILSIYSSFYEVYRFTREIKILSLTFRQMILFALIIFAFSGFYQELNIYPVTVLKYILLVFVLISFFKFAVYYLLQKYRVSFGGNYRRTVIFGVNKKTMALEHFFNKNPEYGYVHSKTFNFKEKKLVNLQECFRFIKENDVDEIYCSISELTNLQISEIVSFADNNLKILKFLPDNKEIYSKKLKYEYYDYIPILSLRNIALEDSFNMVIKRSFDIFFASMVIVFILSWLTPIIAIFIKLESKGPVFFKQSRNGFNFREFDCYKFRSMMPNKDAHLYQATRGDQRITKIGGFIRKTSIDELPQFYNVLFGDMSVVGPRPHMVSHTNIYAKRIDKFMVRHFVKPGITGLAQISGFRGEIETDKDIIGRVKYDIFYVENWSLFLDLKIITRTFLSAVKGDDKAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ91</accession>
    <name>A0A5C6ZJ91_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_08260</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="87" mass="10001" checksum="87856A6EA6342AF6" modified="2019-11-13" version="1">MKKSTQASSPFKIVCTLFGHKYVLSKKVTPHVKEYTCKCCKHQLTTNGNGELTELTPKYQEINDILGDFYSRRLMHMKNQNPISASY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJA8</accession>
    <name>A0A5C6ZJA8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_03200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="156" mass="17209" checksum="0FC998F6C9ABAF25" modified="2019-11-13" version="1">MLASSCSKKDETNDSQFLGTWKLTSYAIDLALDINNDGEKNLNLLTELDCETNEVLKFDNTGVVSSTNTFQHDIKIFKKEADLEMYGVEVECAEGAIGFATTYLPIGENTVVFNTIEATVDGNQLSRTITDGIAIYNEDLSEVVETKSVTLIYSKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJC7</accession>
    <name>A0A5C6ZJC7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038727">
        <property type="entry name" value="NadR/Ttd14_AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13521">
        <property type="entry name" value="AAA_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_28" evidence="1">
        <location>
            <begin position="6"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="179" mass="20778" checksum="9A2BFD2CD86D9F79" modified="2019-11-13" version="1">MNTKQIVITGGPGTGKSSIINELLKRGYPCMEEVSRQVTLEARENGIEQLFLTEPLRFSELLLEARLKQFHDSQNAEIPYIFIDRGMPDVLAYMDYASANYPDHFTSTCEAHRYHSVFNLAPWETIFVSDSERYEDFDQAVQIHEQLVKTYERFGYHLIDVPFESIEKRADFILNFVSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJN6</accession>
    <name>A0A5C6ZJN6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sugar kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_08120</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00584">
        <property type="entry name" value="PFKB_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="3">
        <location>
            <begin position="1"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="308" mass="34149" checksum="AC0039F58887B751" modified="2019-11-13" version="1">MSKLVIVGTVAFDAIETPFGKTDKILGGAATFIGLAASQFDVDSAAVSIVGGDFPQEYLELLSNRNINIDGVEIVKEGKTFFWSGKYHNDMNTRDTLATELNVLADFNPDVPKAYRNADVVMLGNLHPMVQMSVLEQMESKPQLAILDTMNFWMDCALEDLHKVIAKIDVITINDEEARQLTGEYSLVVAARKIQELGPTYVVIKKGEHGALLFHENNMFYAPALPLEEVFDPTGAGDTFAGGFAGYLAKTEDYSFENMKNAVIYGSTLASFCVEKFGTERMQNLTSDEIDHRLKEFKQLTQFNIELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJP3</accession>
    <name>A0A5C6ZJP3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03895</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="135" mass="15113" checksum="80D5457846E1608E" modified="2019-11-13" version="1">MKENVDKQLDDLNRKVMGTSSVEQTSTDFTKNLMSQIHSLNRSSLFRYKPLIATPVWVGLAVLVVAVFGYVFIATSETASETKKNLALNAFLEHNLANPFSGLEMSQAGVYAVVLFCLMLCIQIPILKHYLDKRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJS7</accession>
    <name>A0A5C6ZJS7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF2141 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_04050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018673">
        <property type="entry name" value="DUF2141"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09912">
        <property type="entry name" value="DUF2141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="146" mass="16608" checksum="4BB29367BF714655" modified="2019-11-13" version="1">MKFLIIYIVLFLGIFSDENPRENPSETTKLTIQIDNIAVLDGTIKIGVFNTDIDFLEENATIRDYSLTVTSATEIFVIDDLPKGEYAISMYHDENSDGVLNRNFFGIPKEPYGFSNNVKPKLSAPDYKDCKFSFAKNDTLKIRLIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJX4</accession>
    <name>A0A5C6ZJX4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Probable membrane transporter protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_04310</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002781">
        <property type="entry name" value="TM_pro_TauE-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01925">
        <property type="entry name" value="TauE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="113"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="151"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="187"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="217"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="247"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD90598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="265" mass="28652" checksum="BF4007EF91B9B2EA" modified="2019-11-13" version="1">MELYTILGYVGAFAVGLVLGLTGGGGSIITVPVLVYLVGVNPVTATAYSLFVVGTTSSIGAFQNYRKQLIDFKTAIIFAIPAFTVVYFTRRYLVPAIPDILFQTDNLIITKDLFIMAFFGVIMFLASLSMIQSHEDLESKEKAESIHIPFLILIGICVGLLTGVVGAGGGFLIIPALVLLAKMPMKTAIGSSLFIIALNSLIGFTGDLQSRSIEWPFLLIFSGISILGIIVGVYVSKYISAEKLKRGFGWFTLLVAIAILYRELF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJY7</accession>
    <name>A0A5C6ZJY7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF4856 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_06625</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032331">
        <property type="entry name" value="DUF4856"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16148">
        <property type="entry name" value="DUF4856"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="400" mass="43605" checksum="991A300F0A6302A0" modified="2019-11-13" version="1">MIKSTLSLLIVAGLCFSCSSDDYNNTIPVQIETPASYSFERNAESSVSFDGQTTRILMAEELLNGLMDNTKTEAQLDAMFAHVEGANDFSDANLNASGKNVRSKVAASQDYFSANTTLSSVIKSDFDLWISEQANTVFPNWNNVASAGTAGQLQQTGGGTIRYINGKGFEYNQLVAKGLLGALMTDQILNNYLSPAVLDVGANRDNNTNNVLEEGKPYTTMEHKWDEAFGYLYGTEADPSNPVLGVDEFLNEYLDRVEADADFTGIAQTIFDAFKLGRAAIVANDYELRDAQANIIKEHISKVIAIRAVYYLQGAKSQLASADFASAFHGLSEGYGFIYSLQFTRQPNSDAAYFSHDEVMGMTGQLSEGNGLWDVTPETLDDISQSIATRFNFSIEAASN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJY8</accession>
    <name>A0A5C6ZJY8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08745</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022768916" evidence="1">
        <location>
            <begin position="22"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="242" mass="27727" checksum="990455D233004D64" modified="2019-11-13" version="1">MKPFKHLLAILLIVSGSFNFAQYPTQKPTDKPPTTQDSIAECITLKDMLKQIEARDKRLEATKQSKNNTMNSISQDVKNNQPNAEVGVVYSEDYNNLLTLELPSRVTGFEASKAIKMHPMQGMLSESLMYYWENGREIVIEKSASNRKRKTHSRVDFAKLMWVDSEADMESFLFFIGLDKHPELSKVNDVGESAYWNSKNQNLQMYYNGVSFMLPVIVSFDADLNKEKTIELANLIVEERIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJZ5</accession>
    <name>A0A5C6ZJZ5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_05225</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="121" mass="13322" checksum="5F5B736B14369F96" modified="2019-11-13" version="1">MISFLLLTTSSQSQQSTSKANDRLRVEAETGNPTSVINDGYIELNVLGGTPPFSFKWSNRETALESNKASGLVEGIPYEVIITDSQNKSISRSYTVKAQSITETFNSKFDPLFTLMSSVLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJZ6</accession>
    <name>A0A5C6ZJZ6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bifunctional nicotinamidase/pyrazinamidase</fullName>
            <ecNumber evidence="2">3.5.1.-</ecNumber>
            <ecNumber evidence="2">3.5.1.19</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pncA</name>
        <name evidence="2" type="ORF">ESY86_05020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.-" evidence="2"/>
    <dbReference type="EC" id="3.5.1.19" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008936">
        <property type="term" value="F:nicotinamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="SSF52499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="201" mass="22411" checksum="BE232F17B2F70A2F" modified="2019-11-13" version="1">MKTLLIIDVQNDFMPGGSLSVAGGDKIVPIINGIQHKFDLVVATQDWHPKDHVSFASNHEGKSAFDEIELQGKPQTLWPDHCVQDTEGAQFHPDLKTQKCEAIFRKGTDKYMDSYSAFYDNQHLKSTGLAGYLKEKGVSQLFLCGLAADICVYYSIYDAFKEGFACFFIEDASQALDPEAFKDIKEKMVNLGIQMITSEGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK76</accession>
    <name>A0A5C6ZK76_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Heavy-metal-associated domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_05740</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="SSF55008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022909295" evidence="1">
        <location>
            <begin position="19"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="2">
        <location>
            <begin position="33"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="118" mass="13138" checksum="15CFC309DD55F381" modified="2019-11-13" version="1">MKKLVFTLTVLISTLTFAQNKNAKASLEVDGVCDMCKERIEKAAISTKGVKSAKWSVATHELKLIFDERKTNLDSISKSVAAVGHDTKAYTATDEAYDSVHPCCRYRDEAVKEDHKQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK81</accession>
    <name>A0A5C6ZK81_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_04395</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="117" mass="14131" checksum="C7AE547FB5B7F97A" modified="2019-11-13" version="1">MILHPTINRSVLLVIPKQPFYDWSNTLFPDLEPTTLAEIDEYNSYLLEDELFIDNPKKELKKYWKKIFINELYGQCMDDTTFPHLTWKLFTEWFDFHRSAVISDLTKDPLYTIDYDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKA1</accession>
    <name>A0A5C6ZKA1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_08915</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001094">
        <property type="entry name" value="Flavdoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005625">
        <property type="entry name" value="PepSY-ass_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03929">
        <property type="entry name" value="PepSY_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00369">
        <property type="entry name" value="FLAVODOXIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0249">Electron transport</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="171"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="298"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="Flavodoxin-like" evidence="3">
        <location>
            <begin position="343"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="4">
        <location>
            <begin position="497"/>
            <end position="596"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD89490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="731" mass="82834" checksum="46F775BFFD26F6A8" modified="2019-11-13" version="1">MTISIWRYSHFVLALTSSLFLLIASVTGVILAVEPIAHQAKGYAVQDLDEVSLATTIDALKSNYDDVFALELESSGFVKASVLTIEMETLDIYIDPNTGLQLGEVQEQPFIYSFATNLHRSLFLKSIGRFFVGLISLLLFLIAFTGLLLLAKRQGGFKRLFSKVQKDYFELRYHVILSRWFFIPIVILALTGVYLSAEKFELLPDATITHQEITNTDTAERFEHINDVPFFKETTLDQIRKVEFPFSEDPEEYFQIALKDKEIRVNQQTGQIVSEADYPFVALASRLSWLLHTGEGSVFWSVILLLASASILFFMYSGFAMTLKRRKKVKAISIMPDKDDCEFVILVGSETGTTFDFARRLYNSLNAAGKKVYMTELNNYSTFAKAKHIIILTATYGEGEPPTNARKFETIFPTIKQPNKIRYSIVGFGSLDYPDYCKFAIQVDSLLQIHRDFQALMPLYKINNADFADFERWVEQLSKLLHISLSVEKPKVKKRNYKKNTFKVVERTELNVDDTFLIRLKPKKKTSFTSGDLLSVFPEGTDIPRQYSIARMGNNILLSVKKHEFGKGSSYLHNLNKGDTIQAFIDINPHFHFSKKSASAVLIANGTGIAPFLGMIAQNCNTTINLFWGSRTVASSAIYDDILNGIISKNQNNTIHKSFSREGSKEYVQNLIIQQKDIVLKTVQEGGVVMICGSLAMQHDVLDMLENLRSEYTKIGLDELQHNGQLKMDCY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKG9</accession>
    <name>A0A5C6ZKG9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DoxX family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_04865</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032808">
        <property type="entry name" value="DoxX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07681">
        <property type="entry name" value="DoxX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="106"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD90085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="132" mass="14582" checksum="A850B08EB7EDD536" modified="2019-11-13" version="1">MTTKILISRRSIQLLRVFTSGIFLIAGFNHLLHVEKTAQRIEQASFKGIAHFFGEPQWLIISSGIVMVAAGFLFLIGYKTKWAAIILMAVLIPITLTVQVGQITTLGPLFKNIAILGGLLFFIVNDTNNPLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKZ0</accession>
    <name>A0A5C6ZKZ0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2007 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018551">
        <property type="entry name" value="DUF2007"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09413">
        <property type="entry name" value="DUF2007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2007" evidence="1">
        <location>
            <begin position="8"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="83" mass="9254" checksum="678BEB9B3F494665" modified="2019-11-13" version="1">MSETDYTKIFEGNFIIVQLAMDRLHSAGIQAILKDESESGRLAGFGSSIQGYQELFVNNDELDQARPIISAVKEELESRDMEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL00</accession>
    <name>A0A5C6ZL00_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DUF423 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_06045</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0382 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006696">
        <property type="entry name" value="DUF423"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43461">
        <property type="entry name" value="PTHR43461"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04241">
        <property type="entry name" value="DUF423"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="98"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD90295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="122" mass="13323" checksum="DD9792E99ABA88E4" modified="2019-11-13" version="1">MTQQIIIATAAFFGMLSVIFGAFGAHALKNILSNEQLHSFEVGVKYQMYHAIVLLVLGFNHNGISAAIYWCFTIGILLFSFSIYGLVLSSAKGKKLRFLGPITPIGGMLLVIGWLLVLINAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL17</accession>
    <name>A0A5C6ZL17_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_06605</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="82" mass="8761" checksum="86FC1786FBBD05F9" modified="2019-11-13" version="1">MSIRIGNSCINCANLGANELCKVHGVKVSTSYTCDSFEMRAALKNDPNCVSCVRYETDSCANPQKAAPGMLCSQWAPQSAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLB7</accession>
    <name>A0A5C6ZLB7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dihydroorotase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004151">
        <property type="term" value="F:dihydroorotase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006221">
        <property type="term" value="P:pyrimidine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01317">
        <property type="entry name" value="DHOase_IIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004722">
        <property type="entry name" value="DHOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="1">
        <location>
            <begin position="59"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="417" mass="45521" checksum="6F604D738E2D05B4" modified="2019-11-13" version="1">MNVLLKSASIVDPKSDFHNETVDILIEKGRISAIGKSLENPKKHKEIALENLHVSQGWFDSSVNFGEPGYEERETIANGLETAALSGFTAVALNPNTNPVIDTSSHVAFVKSKAANHATTLYPIGALTKASEGKDLAELFDMKNAGAIAFYDYQKPIANPNLMKLALQYAGNFEALVLSFPQESQISGLGVMNENTMSTSLGLKGNPSLAESLQIARDLFILEYTEGKLHIPTISTAQSVALIREAKQKKQNVTCSVAIHNLLLTDAELHEFETKYKVLPPLRTQTDLDALLEALKDGTIDMVTSDHNPIDIEHKKIEFDFAKYGSIGLESAFAALNSILTTKKTVEVLTKGKSRFGIEEQPIAVGNRADLSLFNPKGNFVFASNHILSRSKNAIFEGKELKGSVYGIFANNQLKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-02-10" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLD5</accession>
    <name>A0A5C6ZLD5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Plasmid pRiA4b ORF-3 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_04475</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024047">
        <property type="entry name" value="MM3350-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012912">
        <property type="entry name" value="Plasmid_pRiA4b_Orf3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07929">
        <property type="entry name" value="PRiA4_ORF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159941">
        <property type="entry name" value="SSF159941"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="172" mass="20194" checksum="9C2C0C7E3B1AF65D" modified="2019-11-13" version="1">MIYKFRILLDSEAEDDVFRDIEIRETDTLEDLHNAITQSFGFDGIEMASFYVSNEQWDQGEEISMIDVNDTYDDKRTMSETALNDVVNKKQTKLIYVYDFLSMWTFLVELADVAEEAEGTDYPNLMFAHGQIPDTAPEKSFEAENFDDEFDEFNDDLDIDDYEDLDFDENWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLP3</accession>
    <name>A0A5C6ZLP3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">YigZ family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_01115</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IMPACT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023582">
        <property type="entry name" value="Impact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001498">
        <property type="entry name" value="Impact_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036956">
        <property type="entry name" value="Impact_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16301">
        <property type="entry name" value="PTHR16301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01205">
        <property type="entry name" value="UPF0029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UPF0029" evidence="2">
        <location>
            <begin position="22"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD91218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="206" mass="23438" checksum="08763AA0E8B67063" modified="2019-11-13" version="1">MIEKDSYKTITKASEGVLFKDRNSKFFGYAFPVTSEEEVKQHLETLKKQHHQAGHFCYAYQIGKTAQELSYRANDDGEPNNSAGMPIYGQIQSFEVTDILIVVLRYFGGTKLGVSGLINAYKTTAEMGLNASKIVKRTINVRYAVRFDYKNMGKVMRIAKEKNLNIVAQTLELSCEIIISVRLKKSQEIFEIFDAIFEVEIKNLND</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLX5</accession>
    <name>A0A5C6ZLX5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carbon-nitrogen hydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_01600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001110">
        <property type="entry name" value="UPF0012_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01227">
        <property type="entry name" value="UPF0012"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD91304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="311" mass="34659" checksum="60E71C4569D19D06" modified="2019-11-13" version="1">MRPFAIAGIQMKVSAVASNVEMMKLKINITMSLYPWVEMVVFSELCAYGPLTHTAEAIPGNFEREMQAMAKKHGIWLLPGSVFEKSEGHIYNTATVINPEGEIVTRYRKMFPFFPYEVGVTPGSGFCVFDVPGVARFGISICYDMWFPETVRTLAVMGAEVILHPTMTGTIDRDIELSIVRAMAAVNQCYFFDVNGLESGGNGRSLVCGPDGRVIYQAEGNEEIFPLELNIERVKRSRELGVLRLGQPLKSFRDHIGQFGIYQQGAQLTYLNSLGPLIKPTKLDTLAKLKMQEHDYEPPINPTGYKGFGEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM07</accession>
    <name>A0A5C6ZM07_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amidohydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_02410</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydro-rel" evidence="2">
        <location>
            <begin position="104"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="482" mass="53630" checksum="99322CAF5AFDBF71" modified="2019-11-13" version="1">MKKVLKFIGIAVGILLLIGLTSYFFWFHNTEEHILKLQASEVYSPEKGNSYLITNANIIDVEAGIVLKNKNLIIQDGVFKLIFEGQVTDSLKTKYEIVDAKNRYLMPGMIDMHTHLNSGGLLPPDESTRPMALEQFARYGVSTIFTLGGHGFNEETTTELKEKQRKHKIVAPMILATGSILTAPGGYPIPFVSGMTGLSEDEIDLDEQGIFTITDETDLDAIFSKKKKLGLNGVKVMVESGLGGASEEPRLSNKLTGKIVQKASQYNLPVFAHVTRIADLQDAVNAGVDVIVHTVEDELLTGAEPFLEKMIRDSIFYTPTLSVAYIFQYVGSAEILEDPFMMQYSSERTNRSLENWPVRQMMVSSYGIDLDLHKENNIKNFTAMYKAGVNVLMGSDARNPSIIPGYSAHKELQFMSEAGMSNAEVLRSATIAPARFLKLENKIGSINEGKIANFLMLDKNPLDDVKNSRTIYKVMLEGYWIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM42</accession>
    <name>A0A5C6ZM42_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosome-recycling factor</fullName>
            <shortName evidence="3">RRF</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Ribosome-releasing factor</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">frr</name>
        <name evidence="6" type="ORF">ESY86_02050</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the RRF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006415">
        <property type="term" value="P:translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00520">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00040">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002661">
        <property type="entry name" value="Ribosome_recyc_fac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023584">
        <property type="entry name" value="Ribosome_recyc_fac_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036191">
        <property type="entry name" value="RRF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20982">
        <property type="entry name" value="PTHR20982"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01765">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55194">
        <property type="entry name" value="SSF55194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00496">
        <property type="entry name" value="frr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RRF" evidence="5">
        <location>
            <begin position="23"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="128"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD90768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="185" mass="20833" checksum="903363FA47266F94" modified="2019-11-13" version="1">MNEDIKFILDSTKESMDSAIKHLEKQFVNIRAGKASPSMLGSVMVDYYGSKTPLSQVANVNTPDGRTITVQPWEKGMLQEIERGIMHANLGFNPMNNGETIIINVPPLTEERRKTLSKQAKAETEDAKIGIRSARKDANNEIKDLEDASEDQQKNAEIDVQQMTDKYVKKADDLYDVKEKEIMTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM61</accession>
    <name>A0A5C6ZM61_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">Malate synthase</fullName>
            <ecNumber evidence="2 7">2.3.3.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">aceB</name>
        <name evidence="8" type="ORF">ESY86_03675</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>acetyl-CoA + glyoxylate + H2O = (S)-malate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18181"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Carbohydrate metabolism; glyoxylate cycle; (S)-malate from isocitrate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the malate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.9" evidence="2 7"/>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00703">
        <property type="reaction ID" value="UER00720"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004474">
        <property type="term" value="F:malate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006097">
        <property type="term" value="P:glyoxylate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00727">
        <property type="entry name" value="malate_synt_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1220.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044856">
        <property type="entry name" value="Malate_synth_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011076">
        <property type="entry name" value="Malate_synth_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006252">
        <property type="entry name" value="Malate_synthA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001465">
        <property type="entry name" value="Malate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019830">
        <property type="entry name" value="Malate_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046363">
        <property type="entry name" value="MS_N_TIM-barrel_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42902">
        <property type="entry name" value="PTHR42902"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01274">
        <property type="entry name" value="Malate_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001363">
        <property type="entry name" value="Malate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51645">
        <property type="entry name" value="SSF51645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01344">
        <property type="entry name" value="malate_syn_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00510">
        <property type="entry name" value="MALATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3 7" id="KW-0329">Glyoxylate bypass</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001363-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD90477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="532" mass="61128" checksum="2F16F0EB51CB698A" modified="2019-11-13" version="1">MENTLLKQSKVRFSKTVKNYYPEILTDEALEFIAALHERFNRKRLELLNNRETQQTIFDTGKFPEFPAETKSIRAGHWTAGKLPKDLQDRRVEITGPADRKMIINALNSGAKTFMADLEDSNSPTWENSIEGQQHLIDANTKTISLVDTKRGKSYKLNDETAVLLVRPRGLHLNERHIIINDEEVSGSLVDFGLYVFHNTKTLLENDTAPYFYLPKLEHYTEARWWNDVFEFAQEYLHVPNGTFKATVLVETITASFQLDEIIFELKDHIVGLNCGRWDYIFSYIKKFRNHPNFVVPNRDQVTMTTPFMDAYSKLVIQRCHKRGILAIGGMAAQIPIKNDENANAAALEKVRLDKEREVKNGHDGTWVAHPALVEIAMTEFNKHMTTPNQMQVTRDDVQITQADLVELPKGSVTEAGIRKNINVGILYTEAWLRGHGAVALYNLMEDAATAEISRTQVWQWLKNEVKLEDGRTFNLELYLALFDDEVEKIITEYGESTIKNTKFKLAIDLFNTLVVSEKFEEFLTLPAYKYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMD3</accession>
    <name>A0A5C6ZMD3_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">L-threonine dehydratase</fullName>
            <ecNumber evidence="11">4.3.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Threonine deaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11 13" type="primary">ilvA</name>
        <name evidence="13" type="ORF">ESY86_02270</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 11">Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>L-threonine = 2-oxobutanoate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:22108"/>
            <dbReference type="ChEBI" id="CHEBI:16763"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="EC" id="4.3.1.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 11">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Amino-acid biosynthesis; L-isoleucine biosynthesis; 2-oxobutanoate from L-threonine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 11">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the serine/threonine dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.19" evidence="11"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00054"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004794">
        <property type="term" value="F:L-threonine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011820">
        <property type="entry name" value="IlvA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000634">
        <property type="entry name" value="Ser/Thr_deHydtase_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001721">
        <property type="entry name" value="TD_ACT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00585">
        <property type="entry name" value="Thr_dehydrat_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02079">
        <property type="entry name" value="THD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51672">
        <property type="entry name" value="ACT_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00165">
        <property type="entry name" value="DEHYDRATASE_SER_THR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 11" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="6 11" id="KW-0412">Isoleucine biosynthesis</keyword>
    <keyword evidence="8 11 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 11" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACT-like" evidence="12">
        <location>
            <begin position="338"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TXD90962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="421" mass="46386" checksum="3E6DFA1FFE94C9C5" modified="2019-11-13" version="1">MQITTTYYPSLASVEAAAKKLEGVAAVTPLMKNVRHSKQFECNILFKREDLQQVRSYKIRGAYNKMSSLSAAETENGIVCASAGNHAQGVALSCKLLKIKGAIFMPAPTSNQKIEQVKMFGEEFIDVILIGDTYDDAFHAAMMHCEDSHKTFINPFNDKKVIEGQATVGLEIIDQALEHPIHYVFVPVGGGGLSAGLSAVFKELSPQTKVIGVEPKGAPSMSTSIKNNQNTELDNIENFVDGAAVKRVGDLNFEICRANLHDVITVDEGKICQVILDLYNKEAIVIEPAGALSIAALDQYAEEIKGKNVVCVISGSNNDITRTAEIKERALLYANLKHYFIIKFPQRAGALREFVVEILGPNDDITHFEYTKKTNRENGAAVVGLQLKDAKDLQPLIARMKLRNFFGDYLNDKPDLFQFLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMD6</accession>
    <name>A0A5C6ZMD6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta fold hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_06325</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AB hydrolase superfamily. AB hydrolase 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000952">
        <property type="entry name" value="AB_hydrolase_4_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012020">
        <property type="entry name" value="ABHD4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005211">
        <property type="entry name" value="Ab_hydro_YheT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01133">
        <property type="entry name" value="UPF0017"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydrolase_4" evidence="2">
        <location>
            <begin position="58"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="319" mass="36594" checksum="C13F82CDDE593287" modified="2019-11-13" version="1">MPILDSTYKPPFQFKNGFLATIYSGLVRKVPLEQQRERMDTRDGDFLDLDWSYAESSSDTLIILLHGLEGHAQRPYVTGAAKLFNQNGMDAVCMNFRGCSGEDNRFYRSYHSGATDDLDDVVKHCLQQKNYSKIILKGVSLGGNVILKYLGEDRMLPKQIKAAIAISVPMHLDGSATELHKMKNRAFAIRFRKHLLDKLRIKQKQFPDRLKDEDLDQIKTLREFDEFYSSKAHGFKDAMDYYTQCSSLQFLKNIIVPTLIINALNDSFLSSECYPIKVAKKNDNVYLEMPKYGGHVGFILKNNVYYNEKRALEFVNSVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMF3</accession>
    <name>A0A5C6ZMF3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_06390</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="101" mass="11785" checksum="ECB81155468B499A" modified="2019-11-13" version="1">MDTDDLSTEAYKGIIIESEKFNRDLTLQFGVLASACKDEEDYLNKSEQLISELRSCDKEDLIYIFFGNLPDIKSLNLTLDRITENIDSVRKTPKEQRHYEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZML8</accession>
    <name>A0A5C6ZML8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glu/Leu/Phe/Val dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_00980</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the Glu/Leu/Phe/Val dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016639">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006095">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006096">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006097">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016211">
        <property type="entry name" value="Glu/Phe/Leu/Val_DH_bac/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42722">
        <property type="entry name" value="PTHR42722"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00208">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02812">
        <property type="entry name" value="ELFV_dehydrog_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000188">
        <property type="entry name" value="Phe_leu_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00082">
        <property type="entry name" value="GLFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00839">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ELFV_dehydrog" evidence="5">
        <location>
            <begin position="158"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="2">
        <location>
            <position position="94"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="194"/>
            <end position="199"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000188-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000188-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD91192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="367" mass="40496" checksum="14B1C8E411A15958" modified="2019-11-13" version="1">MTSEVISTKELTKMDPVFGQMSFDNHEQIVFCNDKDTGLKAIIGIHNTVLGPALGGTRMWNYSNEWEALNDVLRLSRGMTFKSAITGLNLGGGKAVIIGDAKTQKTPELMRRFGEFVHSLSGKYITAEDVGMNTEDMDIVREVTPYVTGISESKGGAGNPSPITAYGVFMGMKAAAKFKYGSDVLEDKSVYVQGIGHVGEALIENLLNEGAKVTISDINQERLEEVRSKYDVTIYGGNDLYSEKMDIYSPCALGATINDSTINKLQASIIAGAANNQLEDEVRHGNMLKKKNILYAPDFLINAGGIINVYAELENYDKQEIMRKTENIYNTTLDIFNRAESNNVTTQVAAMNIAKERIEKRKREQSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMM8</accession>
    <name>A0A5C6ZMM8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Enoyl-[acyl-carrier-protein] reductase [NADH]</fullName>
            <ecNumber evidence="6">1.3.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_01030</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 2,3-saturated acyl-[ACP] + NAD(+) = a (2E)-enoyl-[ACP] + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:10240"/>
            <dbReference type="Rhea" id="RHEA-COMP:9925"/>
            <dbReference type="Rhea" id="RHEA-COMP:9926"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:78784"/>
            <dbReference type="ChEBI" id="CHEBI:78785"/>
            <dbReference type="EC" id="1.3.1.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the short-chain dehydrogenases/reductases (SDR) family. FabI subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.9" evidence="6"/>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00391"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004318">
        <property type="term" value="F:enoyl-[acyl-carrier-protein] reductase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016631">
        <property type="term" value="F:enoyl-[acyl-carrier-protein] reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014358">
        <property type="entry name" value="Enoyl-ACP_Rdtase_NADH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43159">
        <property type="entry name" value="PTHR43159"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000094">
        <property type="entry name" value="Enoyl-ACP_rdct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5 6" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="6" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5 6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4 6 8" id="KW-0520">NAD</keyword>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="150"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="21"/>
            <end position="22"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR000094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000094-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000094-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD91202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="276" mass="30321" checksum="91B97C86C9D2403C" modified="2019-11-13" version="1">MSYNLLKGKRGIIFGALDANSIAWITAERVHEEGGTFVLTNAPIAMRMGQIKELAEKTGSQIVPADATSIEDLENLVAKSTEILGGKLDFVLHSIGMSINVRKGKHYTDQNYDWTQKGTDVSAMSFHKTMQTLYKADAMNEWGSIVALTYMAAQRVFPDYNDMADNKAYLESIARSFGYFFGKDKNVRVNTISQSPTPTTAGQGVKGFDGFIAYAEKMSPLGNATALDCANYTITLFSDLTKRVTLQNLYNDGGFSNMGVSDAVMETFVDNVDKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN36</accession>
    <name>A0A5C6ZN36_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_01340</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 3 4">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the FKBP-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="5">
        <location>
            <begin position="7"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD91259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="143" mass="16142" checksum="5A5C3B49F8C82A0C" modified="2019-11-13" version="1">MSQVKEKDTVKVHYTGKIKENGQVFDSSQDREPLEFTLGEGMLIPGFENAVIDMKVNDKKTVEIPMTEAYGEVNKELFHKVEKQQLPEEVKPEVGLGLVSKDAQGNEHQFRIAEVNEDHIIVDGNHPLAGQELVFDLELVEIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN88</accession>
    <name>A0A5C6ZN88_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_02950</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="3"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="122" mass="13480" checksum="515B131C979B6415" modified="2019-11-13" version="1">MIKILVVDDDRIIGEMLKFMLSSKGYLPVISNKPEQTIDNILQHDIDLVMLDQFIFGVSGAAICKELQETETTAHLPILMMSADTAVETKCLSAGATDFIAKPFEMKLLFSKIEAMLQQATG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNA6</accession>
    <name>A0A5C6ZNA6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TraG family conjugative transposon ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">traG</name>
        <name evidence="3" type="ORF">ESY86_05355</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022509">
        <property type="entry name" value="Conjugation_ATPase_TraG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043964">
        <property type="entry name" value="P-loop_TraG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024451">
        <property type="entry name" value="TraG_N_Bacteroidetes"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12991">
        <property type="entry name" value="DUF3875"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19044">
        <property type="entry name" value="P-loop_TraG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03783">
        <property type="entry name" value="Bac_Flav_CT_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3875" evidence="1">
        <location>
            <begin position="5"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="domain" description="P-loop_TraG" evidence="2">
        <location>
            <begin position="396"/>
            <end position="798"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="800" mass="92458" checksum="F18424F4B0FDB641" modified="2019-11-13" version="1">MNKMNLSAYQPIADIQDNIIFANNGNVVLCYKGNLPEIYSLSEKDFEDMHGAWFQALKSLPVGTVVHKQDIYLKKSYSSEQLPNTTFLEKATNEHFKGRGHIEHKCYLFFILTKNKALNNPKYVNPFRKISKGIVQGLDDNIKSFVNSVSDSVSFINNSRKMAFLPLKAEEIQKLTNGYFNGFNEGFDTDIILDKKSVNIGENHFDALAINSELCFGESVQSSKTNEKFTSDDFVFHQGFIDGLGLTLNENHIVNQILYLDDKQKWRKLLDKKVEELNKSSNFGSQNKVVLGKIQHILDQINADDNARIVRGHLNIVYWAKEAKELDKITSKIKTEFKELDIIPYYPRGEERKNYILNSYCCFSSNFSNNDLYVTDLKHALCLFINNTNYKSDNTGIIFNDREHNIPVLKDVWDEKKKRIKARNFAIFAPTGEGKSFLANNILRQYFESGVRLVIIDLGGSYTKFAKLYPEKYTVLRYESGKNLGINPFYISDVKDLTPERLEDLSVFLFELFASDMKVTKAQSVSVKKILRHYYDSTTEKHSLDGFYSFIERNQKDLLKTLKIHPDYFNVTSFLHVMSEYVGDGLYSFLFEVSEDQTYKIEDKRLIVFELDEVKDNKEILSVMLKLIKSAIQRTIWKNRAEKGIILFDEFAKQLKFDNVLESVEFYYQAIRKQNGAIGIILQSINQLPNNSTSASILENTQVIYSLNNEKGYDELVKRLNLSSHDLNQLKSIKNNLSGPRKYTEMFIKIGRESNIFRLEVPKEVYAAYLTDGQENEDIMKLYNEHHNMEKAIIQFTSKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNB7</accession>
    <name>A0A5C6ZNB7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="114"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="163" mass="18961" checksum="0FAAA71C48D3D506" modified="2019-11-13" version="1">MKKLLLILSVTAVIFISCDDKKKDLSAQYDTLMTESDKIEMAHQKFEEVHKSMMGEHQKFSEEVEGMEVQDSTLLGDVAKHGVILKKHDAIIESHAAIIEGHKKLKTDFDNLNAVEMEAEIKQMKKDHDKMMEEHSSMEDEHEMMMKEHKDLKERMVENMEEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNW2</accession>
    <name>A0A5C6ZNW2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_01370</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="7"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD91265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="132" mass="14816" checksum="0EA16EC054352AE4" modified="2019-11-13" version="1">MTQTTKRFLLVDDDPLNNYLTKMVLKKSFEGAQVKDFSIPEDGLGFIGSAPNQHPSDEKTILFLDINMPTLSGWEFLAAFDRFDASIKAQYNIYILSSSVDLNDINLAKANPLVLDFIEKPLNKAKLVELFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNX1</accession>
    <name>A0A5C6ZNX1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NlpC/P60 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_01435</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C40 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000064">
        <property type="entry name" value="NLP_P60_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041382">
        <property type="entry name" value="SH3_16"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00877">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18348">
        <property type="entry name" value="SH3_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51935">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NlpC/P60" evidence="2">
        <location>
            <begin position="121"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD91275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="249" mass="28423" checksum="5335E07ECFC9F71E" modified="2019-11-13" version="1">MLYAICNLSIVPLRAEPSDKSELVSQILYGEVFKVIEQRKYWSKIQLAYDTYEGWVDNKQYIEISETDFASICSQDPIMSSDLLEVVQDQQHQLTTIPLGSSLNGLELMKHHYDGKLTRATNKKDHLVSTAFLYLNAPYLWGGKTPFGIDCSGFTQMVYKLNGYHLLRDASQQSKQGQPLSFIEESEAGDLAFFDNNDGEIIHVGIIMEDNYIIHAHGKVRIDRLDHSGIYNAERNVHTHKLRVIKKII</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNX9</accession>
    <name>A0A5C6ZNX9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-deoxy-manno-octulosonate cytidylyltransferase</fullName>
            <ecNumber evidence="2">2.7.7.38</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">CMP-2-keto-3-deoxyoctulosonic acid synthase</fullName>
            <shortName evidence="2">CKS</shortName>
            <shortName evidence="2">CMP-KDO synthase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 3" type="primary">kdsB</name>
        <name evidence="3" type="ORF">ESY86_03370</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>3-deoxy-alpha-D-manno-oct-2-ulosonate + CTP = CMP-3-deoxy-beta-D-manno-octulosonate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23448"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:85986"/>
            <dbReference type="ChEBI" id="CHEBI:85987"/>
            <dbReference type="EC" id="2.7.7.38"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Nucleotide-sugar biosynthesis; CMP-3-deoxy-D-manno-octulosonate biosynthesis; CMP-3-deoxy-D-manno-octulosonate from 3-deoxy-D-manno-octulosonate and CTP: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the KdsB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.38" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00358">
        <property type="reaction ID" value="UER00476"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008690">
        <property type="term" value="F:3-deoxy-manno-octulosonate cytidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033468">
        <property type="term" value="P:CMP-keto-3-deoxy-D-manno-octulosonic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009103">
        <property type="term" value="P:lipopolysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02517">
        <property type="entry name" value="CMP-KDO-Synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00057">
        <property type="entry name" value="KdsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003329">
        <property type="entry name" value="Cytidylyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004528">
        <property type="entry name" value="KdsB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02348">
        <property type="entry name" value="CTP_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00466">
        <property type="entry name" value="kdsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0448">Lipopolysaccharide biosynthesis</keyword>
    <keyword evidence="2 3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="243" mass="27993" checksum="C46A1E2DEFE69C61" modified="2019-11-13" version="1">MKIISMIPARYGASRFPAKLMQDLGGKTVILRTYEATVATKLFDEVYVVTDSDIIFNEIETNGGKAIMSKEEHQSGSDRIAEAVADLDIDIVVNVQGDEPFTERESLEKVLKVFQNDHENKIDLASLMVEIHDWDEIANPNTVKVIVDQDNFALYFSRSPIPYPRDREAGARYFKHKGVYAFRKQALLDFYKLPMRFLEATEKIECIRYLEYGKRIKMVETQVEGVEIDTPEDLERAKKQWSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPD5</accession>
    <name>A0A5C6ZPD5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">T9SS type A sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_01025</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022884761" evidence="1">
        <location>
            <begin position="20"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="domain" description="Por_Secre_tail" evidence="2">
        <location>
            <begin position="923"/>
            <end position="990"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD91201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="992" mass="103569" checksum="9FBE0849700476B5" modified="2019-11-13" version="1">MRKITFLIFAQLFSLCLFAQSTINITTSGGNYATEKWVSITTEVNGAGTQIFGQGDGTYGNGQGLINQDIELPAGTYYVNCYDRYADSWDGTLISVTAYGAVIGDNGGVTPDDGTDGDAASSWEDPELELETSFEIIVPEALCSIPDATFTVDNGCPTSDGTFSITVDISDIGTATSVSISDDQGTALQTGLAAGSYTFGDYADETDVVITVANDDEPTACFKTSGTLTFSGICPPANDECADAIELSVNTDFECGSFTAGTNAGATASSQEDNITGTPNTDVWYSFEATAEEHRITLTNVVNQGGGTSTSTDMGMGVYDSTGGCDALVLFDDSDPNTLNLEGLTVGTVYYVRVYGWFSSIQYNTFDICIGTPCQADAGTLTADAASVILSGATATISATEDTAPTVPSDYDVTYVLTLGTDLVIEEVAATPSFDVSTLGLYTIHTLVALTDPAFSADSNFLDLSVVAFGTTTAGEVLDIVGDNDICAALDVAGAPISVNDGSELDFYNVQYVEETGSDPSNGSSQSLTVEVGTPITVYAKGYEDGLTNPAGQAAGIECWIAINDENTDPATWDASVWQEATYLGDNGNDDEYSYETSGTPIGANYVAARWRLNNADFTYGAFNGAWDGTTNVNIELIIEPLANDDCAGAQSVMQETEIADAASATAIPGTIDGATDSGLAAEACSGFVGTANDDVWYSFEALTSEVNITYEIAWDGVAQLYSGTCGALTAIDCADSTFGSGPQEEIQATGLTVGEIYYTRIYQFFAGSTAGKTFDLKIWSPCTADAGTLTADATPVSLSGGTATISATPNADIVVPTDFDVTFVLTSGTDLVIEQAGAAPSFDVTAVGNYTIHTLVAETSDDTSPNYLDLSVIDFGTTTAADVLDLVSTNSLCASLDAAGAAIEVDDALSVDGQDNRAFTYFPNPVKDQLHLKAQSPIENVVIFNMLGQEVMNVSPRSMEVDVNTNTLESGAYFATVTIGNTSKTIKLIKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPH8</accession>
    <name>A0A5C6ZPH8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HAMP domain-containing histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_04110</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="155"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="363" mass="40887" checksum="005E02EE7A0B21B0" modified="2019-11-13" version="1">MNTTEQELKERIKELTCLYEVSSIISHANYELIQDTLKAIAFSLKKAFQYPEKTDITINTSVFSFSTKAIQDPAITLRSNVLVFNKNKGQIIAHALASEFKPTDFPKEEQLLLDNVALKLGSLFERIEIETNERSLKRQMERADRLGILGEITAGIAHELNTPLANILGFAELLQNELKNDPKHAEDLDKIIQNAIFSREVVKNLMFFACEMPQEMKRVNIIPNIKNAIHLLDATFRKEKIKYLVKIDAEELWLRADPIQITQIFFNLLINAIYFSPENGLVEIEAHQSETDIILKIADEGKGFTAEALERIFEPFFSTKPMGDGSGLGLSVVHGIITSHKGTIVAENNSKNGATFTITLPKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPJ9</accession>
    <name>A0A5C6ZPJ9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cytochrome b/b6 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_02995</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011577">
        <property type="entry name" value="Cyt_b561_bac/Ni-Hgenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016174">
        <property type="entry name" value="Di-haem_cyt_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01292">
        <property type="entry name" value="Ni_hydr_CYTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81342">
        <property type="entry name" value="SSF81342"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="150"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="Ni_hydr_CYTB" evidence="3">
        <location>
            <begin position="6"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD90936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="192" mass="22219" checksum="4A0CFD3C5F4F33F8" modified="2019-11-13" version="1">MEKTNYSKIYRILHWAIAISFTLLLITIFLRLTWMNKYNVAAIIQDYLSTTGQTLSQDQLIVLAKQIRQPMWDWHIYIGYVLTGLFSLRLILPFFGSMKFQNPLARDLSLKDKFQKWTYIVFYLCVVISLVTGLIIVFGPKEFKKPMEEIHVLGIYYLVGFIVIHIAGVLIAEFTSQKGIISRIVSGSKKES</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZRI0</accession>
    <name>A0A5C6ZRI0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">T9SS type B sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_01020</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1220">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026341">
        <property type="entry name" value="Bac_Flav_CTERM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011635">
        <property type="entry name" value="CARDB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014755">
        <property type="entry name" value="Cu-Rt/internalin_Ig-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07705">
        <property type="entry name" value="CARDB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04131">
        <property type="entry name" value="Bac_Flav_CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022868975" evidence="2">
        <location>
            <begin position="20"/>
            <end position="1058"/>
        </location>
    </feature>
    <feature type="domain" description="CARDB" evidence="3">
        <location>
            <begin position="313"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD91200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1058" mass="114411" checksum="164C2203DE810C3F" modified="2019-11-13" version="1">MKYLVAFCILFSCGNIIHAQNDVPLTLYQQFNGKYGYTIIGNTQNEFDNYQLPPPPCQMITQSSAGLNLNVDQTIEGAYLYWAGIGDGSLPVNLQLNGNIITPDLTFISDINSPFEAVPYFSSFKNITSFVQQEGNINYTVSNLNLNSIIDLYCSNAIYFSGWTIIVVYEDFSLPSTQTNIYHGLKFVGLNTTVSVDILINNLNIIDPQGASMSYVGYNGSPNIFLDESILFNGNTLSNALNPPDNPFNGSNSFTGSTTNWNQDIDTFDISSYINVDDTQANIKMNSFYIRFISSIVTSIRSELPDATALLTQVTGQELCDNRDLVVDYTIANTNSNASLPANVPISFYADNTLLQTVTTATPIAIGGSLDLQSTLSIPLTVPNTFTLKIVVDNTIANVSSVAESNESNNEDLQTITLVSDGDITPIFTLQDTFCEDGTVASLPAVSDNGISGSWSPSVINNQTDGSYVFTPNAAQCASPFTLDVTISPNASPIFNLQDTFCQGDTVPNLPLISANAISGTWSPSGIDNQMSASYMFTPTTGQCAIAFTLDVMVSPTVTPSFALQDTFCQDEPVPNLPSVSNNGIAGSWLPTVIDNQTDGSYVFTPSTGQCASAFTLDVTVSPTVTPKFSLPTVLCQNAEVPNLPTSSDNAISGSWSPNVITNQGSGTYVFTPSDGQCALAFTLEVTISPNVTPSFTIQDTFCRDESVPSLPTSSNNSILGSWSPSSIDNQASGSYLFTPNSGQCALPFTLDVMVSPNVIPVFSIENTYCQDATVPNLPTSSNNAILGSWSPISIDNQTDGTYVFTPSDGQCALPFTLDVTIALPTLTIENVSICEDEDGNSLSSILLDTGLGGFNFTFAWFENNIPIANTLSSLTVSTPGGYEVIATPVSLGCEQQFQFLVTALQPLTADYIVSDDFEANQTIAVEASGGSGSYLYSFEGLPFQQSPVYTVLDGGAVSVIVKDVNGCYETSTTLTLWQYPRFFTPNGDTYNDTWGIKTQQQIRIEIFDRYGKLLKTLLTNDRWDGTYNSQSLPANDYWFVLHYKQNRTFKSHFTLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZRJ1</accession>
    <name>A0A5C6ZRJ1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bifunctional metallophosphatase/5'-nucleotidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_01075</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 5'-nucleotidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110165">
        <property type="term" value="C:cellular anatomical entity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008252">
        <property type="term" value="F:nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009166">
        <property type="term" value="P:nucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006146">
        <property type="entry name" value="5'-Nucleotdase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006179">
        <property type="entry name" value="5_nucleotidase/apyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575">
        <property type="entry name" value="PTHR11575"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01607">
        <property type="entry name" value="APYRASEFAMLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00785">
        <property type="entry name" value="5_NUCLEOTIDASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="2">
        <location>
            <begin position="35"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU362119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD91210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="303" mass="33772" checksum="D5BACA24E71C4F9D" modified="2019-11-13" version="1">MKRRDFIHQTSAASALIGLGGFGLSSFSSATKKITILHTNDVHSHIDPFGPEDGRNPNQGGVARRASLIESIRAENPNTLLMDAGDIFQGTPYFNYYGGELEFKLMSMLKYDVATIGNHDFDNGIDGLYAQLPHAKFDFVSSNYDFSNTIMDSHVKPYRIIEKDGIKVGVFGLGIELYGLVDENMYKETKYLDPIETTQEMTRILKQQEHCDLVICLSHLGYKYSRLPEKISDLSLAEKTKDIDLIIGGHTHTFLKKPTIIKNAEGKNTLVNQVGCYGINLGKIDFYFDANKNKSAEGTSIIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZRL2</accession>
    <name>A0A5C6ZRL2_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Beta sliding clamp</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">dnaN</name>
        <name evidence="13" type="ORF">ESY86_01185</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Forms a ring-shaped head-to-tail homodimer around DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the beta sliding clamp family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009360">
        <property type="term" value="C:DNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00140">
        <property type="entry name" value="beta_clamp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001001">
        <property type="entry name" value="DNA_polIII_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022635">
        <property type="entry name" value="DNA_polIII_beta_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022637">
        <property type="entry name" value="DNA_polIII_beta_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022634">
        <property type="entry name" value="DNA_polIII_beta_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30478">
        <property type="entry name" value="PTHR30478"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00712">
        <property type="entry name" value="DNA_pol3_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02767">
        <property type="entry name" value="DNA_pol3_beta_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02768">
        <property type="entry name" value="DNA_pol3_beta_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000804">
        <property type="entry name" value="DNA_pol_III_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00480">
        <property type="entry name" value="POL3Bc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00663">
        <property type="entry name" value="dnan"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 9" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="5 9 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA_pol3_beta" evidence="10">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_pol3_beta_2" evidence="11">
        <location>
            <begin position="129"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_pol3_beta_3" evidence="12">
        <location>
            <begin position="245"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TXD91230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="372" mass="41084" checksum="46AC0B12F3F83A9E" modified="2019-11-13" version="1">MKFIVSSTYLLKQLQVLGGVINNSNTLPILDNFLFEIQGSQLTVSASDLETTMSATLNVESDEDGSIALPARLLLDTLKTFPEQPLTFVVEDNHTVEISSNHGKYALAYADGNEFPKSVELEDPSTTTIAGEILATAISKTIFAAGNDDLRPVMSGVFFQFSTEGLTFVATDAHKLVKYTREDVKADQVAEFIMPKKPLNLLKGILAASDEAVTIEYNDSNAKFTFENSVLVCRLIDGKYPNYEAVIPKENPNKLTIDRTQFLNSVRRVSIFSNKTTHQIRLKIAGAELNISAEDIDYSNKAEERLTCDYQGDDMQIGFNSRFLTEMLNNLTADDVQLEMSMPNRAGILTPVDGLDEGEHVTMLVMPVMLNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6Z999</accession>
    <name>A0A5C6Z999_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000125">
        <property type="protein sequence ID" value="TXD85829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD85829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="105" mass="12237" checksum="2627215CC2CB9164" modified="2019-11-13" version="1">MILNLISAVFQLINLNETGIGFKEIIFFFTGTISIIILYIFIFKKSTLEKIPINKIERLNEKSIFGKKRFSLKLKNGMKRDLTELKTQTEYNELKKLFSEIGITN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6Z9I6</accession>
    <name>A0A5C6Z9I6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20785</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000127">
        <property type="protein sequence ID" value="TXD85806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD85806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="63" mass="7069" checksum="91ED7F72F9B8E571" modified="2019-11-13" version="1">MIKRNLSSILVIIAMLLNILGFDFMNINTASTKFWLFLGATIVLIASVILIFVNESKNNKNPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6Z9V4</accession>
    <name>A0A5C6Z9V4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TSPc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_19810</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000048">
        <property type="protein sequence ID" value="TXD86598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_006988391.1">
        <property type="nucleotide sequence ID" value="NZ_VORO01000048.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00245">
        <property type="entry name" value="TSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022908899" description="TSPc domain-containing protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="domain" description="TSPc" evidence="2">
        <location>
            <begin position="219"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="490" mass="56494" checksum="8D04CC435042A72E" modified="2019-11-13" version="1">MKNNLFKLSFLLILTISSSIFAQDSIVYQPEEMKKDILKFKDALIKTHLGIYEYQTPEEFERFINHLIIDASQPLEPKDYYKLILKLVANIRDAHTDAHPFRSLGKKMSTYKWLPFQVFVKNDRVYITRAMCKEPISEGSEILSIDGNLSNKIVIEMFKHYSADGLSTSGMEHYLGVSYRAFHKIYPFVFEDKPTYQLTYRDFQTKQIMTAQISALPKKEYLTEELKRYGNNNSKYKPKAFDFKIDNAKQYAYLQLTRFFKDNFQEPESTYPDYYAKSFKEIADNNVKTLIVDLRDNDGGKLSNAAHLLRYFVKKPFRPTNEITTKGNDEYYLKTIGDTLNFNSQYGLERKANGNYKVTKFDYLTELKVFEPIDKYSFDGKIIVLIDGGAASAGGAAPALFREYTNAILVGKETFGTAGVGNGINRIYVKGDNTDVAISIPLMHSDIAIDEHLKRRGTIPDYEISNSIENIVNKRDHMMEFVLEKLLLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZB16</accession>
    <name>A0A5C6ZB16_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">dCMP deaminase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_18815</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytidine and deoxycytidylate deaminase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000034">
        <property type="protein sequence ID" value="TXD86922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004132">
        <property type="term" value="F:dCMP deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006220">
        <property type="term" value="P:pyrimidine nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01286">
        <property type="entry name" value="deoxycytidylate_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016192">
        <property type="entry name" value="APOBEC/CMP_deaminase_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016473">
        <property type="entry name" value="dCMP_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015517">
        <property type="entry name" value="dCMP_deaminase-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035105">
        <property type="entry name" value="Deoxycytidylate_deaminase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11086">
        <property type="entry name" value="PTHR11086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006019">
        <property type="entry name" value="dCMP_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00903">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="7">
        <location>
            <begin position="8"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR006019-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR006019-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD86922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="143" mass="16128" checksum="76A26FF1950EAE2E" modified="2019-11-13" version="1">MSKKKQLRYDKAYLRIAQEWGKLSHCKRKQVGALIVKDRMIISDGYNGTPTGFENYCEDDEGYTKWYVLHAEANAILKVAASTQSCNGATLYITLSPCKECSKLIHQAGIVRVVYKEGYKDDSGLQFLEKAGIELQLIEDLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBC9</accession>
    <name>A0A5C6ZBC9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_20665</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000101">
        <property type="protein sequence ID" value="TXD86005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="165" mass="19325" checksum="08E155400578D230" modified="2019-11-13" version="1">MDIEYLPNKGFILNSLKFEWNNERNSVREKLGMKHKEEDKIIDVAEFFDGDESMNIHQKRDVYENLNSKKDMLFLNYDKENRLRDLEVHYGFDILIDNIRLDFGTEISDLIKQFKNIGTEYSELEKGNYFLPKLKITIADSESMGGDGTGLSYFYATSDISHLTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBH3</accession>
    <name>A0A5C6ZBH3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Tryptophan-rich sensory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_20315</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TspO/BZRP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000065">
        <property type="protein sequence ID" value="TXD86385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15904">
        <property type="entry name" value="TSPO_MBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038330">
        <property type="entry name" value="TspO/MBR-related_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004307">
        <property type="entry name" value="TspO_MBR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10057">
        <property type="entry name" value="PTHR10057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03073">
        <property type="entry name" value="TspO_MBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="133"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD86385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="158" mass="18352" checksum="EBB4610BBB694927" modified="2019-11-13" version="1">MKKGNLIYLLLSTGICVVFAIIGGLLVGNSLENWFTEIKHPWFSLPMIGWYIVGGLYYIMAIAILYRLLIAKDGLQRRLAICLTIAMIAGNEFWNYLFFGLESTYAGFIGLIPFTLIVVVLFVRLWKFQQRTAWILLPYVIWLGYDIIWTYNLWILNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBK9</accession>
    <name>A0A5C6ZBK9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">T9SS type B sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000029">
        <property type="protein sequence ID" value="TXD87139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026341">
        <property type="entry name" value="Bac_Flav_CTERM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025667">
        <property type="entry name" value="SprB_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13573">
        <property type="entry name" value="SprB"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04131">
        <property type="entry name" value="Bac_Flav_CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="3305" mass="346343" checksum="5277F67EFE54664D" modified="2019-11-13" version="1">MKNPTNLQCKQWLRSFVVNAVHSVKFGAERFAKLKATPQNSEFLGSVSNSKAISVLPMVMVMMLLFSVKAFAQLPVPFTPRLDGGSIKVKGDILFIGNSTVTGAGLPSPYNGNGINNNNEGVYINTASGGDPAIFSSSSADLTIDTDCKKILYAGLYWASVYPNEIGTNSNVGFEGTQRFEDWNQVKFKLPGGDFIDLEADSDPDMVGEEDDIIFDGYKYYGPNVEDSFKDSPIICYKNVTNLVQGLAEADGTYAVANLRATRGFRRGGCSAGWTLVVIYESPILPSKYITVFDGYAGVQNNTTLDIPVSGFQTLPAPYPVNANISVGALEGDIGIQGDSFRFKANSVANFTVLSDAINQANNFFNSTITINGVHNINRNPASLNTLGLDINNVKIPNPGNIVIPNDETGGALKLTTNGDGYGAFVTSFAVEIIEPKIVLTKIVEDEFGNNIGGQIVNLGQELNYVLGFRNSGNDDATDFTIRDILPINIVFDYPSDMTYLPPGVSVESYNPATREIVFRIDDSVVEEFDPVLEIRFKVTVVESCSLLVDVCSDLINNQAFATYRSSLNPSFLITDDPSYSSNTGCLLAPQATNFLADLNDCIFTEEIILCGDTVDITAANGYDSYAWSSSPTGTPVIGTTQTITVSNTGIYYVRNTAIAPCQSIDQIFNVELYGGTITNPVIPYADEVATCPNDGKLLPNIFLCGANDQRDIQTNISGATSIIWEQLDESSCGAVSNTDCANENSACTWNEVQTGPDFIADAAGQFRLTINYEGGCFTQFYFNVYQNLLDPTVATQDIVCTTPGSITVGGVPNGYEYSLDGASYQSSNIFSVNTPGFYTVYVRQVGVASNPCVFTVPDIQIRSRNFSGSTLVIQPYCNGDKGSIQIAANDANPQYTFTLYQGATLVNTVGPAMANNHTFENLNPGTYTASLTTEDGCTFSEDITIINPPILTVTAAITSPLTCNDGEITMYPSGGTPPYFYFVNSTTEFQTEPVFTVTAPGTFDITVVDANNCSATTNLVIDTIPPPDFTVNTTDITCASAGNTGGIDINVTAANGNSIQYSIDNGITFTNSSVFNGLDVGDYEVVVQYTSGNSVCFTDAQTVTITSATAISGTAELSANLTCANSATITVIDVVGGDAPYTYSIDGVNFQTSPDFTGLTAGTYTVTIKDANVCTSAANDITVAPLDPVTDISFDNTPLTCPLNVSTVSIINVVGGTGTLEYQIIAPASAQTAYQTSNEFQDLAPGTYTFQVKDANDCTYSESYTIAPLAAITVVGQNVNDISCFGAADASVQFTISGTANFNYTINGGASTAGTSPVVLTGLSAGSYTLIVTDTATNCNATETLTVNGPTSALAMTTTVAPITCLQNGSVVINATGGWGGNSYSLTLPDGSVLPGQSNNTFANLSQDGTYTVTVVDANNCTITDTLVLNPTEAPIASIDVASDLCYDGTNAATIEVSVTSGQAPYEYSLNGGAYQTSNIFADLVPGSYTVTVRDAYGCTVTLSTQTIAQQPSVNTALTKDLDCTASPDAVITGTIAGGTAPFTYSVSIDGGAYTSLGSTGSPFTYSTGTPGTYQFQISDAQGCTAQSGIITINPISPPALSLVTQTQPILCNGDTNAAIQINIDTTVGTPPFLTNVNNDTTGVDYGTQTSGLPAGTYTITVTDARFCTATDTVTIGEPDAIDFDLSKIDITCNNPGGSSLGSITVENTSGGTGPFTYFITNNFGDSIPNNPYTALTGEDYQFDIINFGIYTVNVVDSNGCNLSKQITIASPPSDLVIDVTPSVPDCVSGGTVTVEAISAVGSGSYEFGILEFNTVPYTLNYLGPDVPGGAIRTFNNLIPGVVYTFVVHDTTTDCYFVKSADIAIPAFSPLTSTVTPNNVSCTGNDNGSVTFTVDNFDNTTSSIEYSIYRAYTNILVDGPTNLPVTFGVPETVTTPTSLEVGQYYILFTENGTGAYSGCESSSVIFEITESPLLLSLSTSVDQNANCNASSGVISAVAQNGTPPYTYQVTTTATPIPLATDPAWASASTFNLDAGDYYVHAKDKYGCIVSSPVVVLPMDPTPAISAVITNQCDTVEGAYEIEVNLDTPGIAPYSFSIDGGAFQTQTAPFTLSNLSSGSHTVELQDANGCGNLVTVNIEAPIGLTPAVTALPSCTNNDGILTVTGTGGTGTYTYGISPNPASITLTGNVFSGVPSGTYTVTITDTVTSCTEDVSVTLDAATPVTFTTTVNDVSCNAGTNGVISVNLPSSNDNPVYTYEIIAPMVVPAQNSNVFSGLSAGTYTVQVTSGRGCAATQDVVVGEPELLQVSGTATDFACAIDNSVNTSTLAITEVGGMAPYTYSINGTNYFTSNTFDIIDTGSIQTITFFVKDANGCLASNTVTLNPLPTLTLAAVAIATPIDCNNTGTVSIAVTGGSGNVTYQMLPSGTPQASNTFSIIVPGDYYFQVNDIDTGCNVATAAITVAPYDEVDVNAVAISDVTCFGDANGGFEINLTGYTGEYSYEVLDAAGTSIIGTVTANTSTDPQTVSGLTAGNYTTVITETASPFCSATSNVVTITSPSAALTLDASETSNVTCTDDQGTITAEATGGWGTLEYELSGAASVAYSSNGSFSGLSAGAYTVTVRDAEGCEASVPVTLTLPTPIDATFTPSTTLLSCFGDQDASITVTNVTGGQGENFTYTLNTILPTASVSGPQGSNTFSNLAAGTYSVSITDGLNCVDTSADIVITEPTEVEASLVTATTQSCLIDPSLTLSATGGTPPYTYSATEGFATTLGTFTTSTTFDVAPGTYMYYVKDANGCLATVSNEITIEVLPTLILNLELTNATINCAGDNSGFIVASAQGGLGNYVYTLQDAGGTTIPATQNTPGTFTGLLAGNYIVMVESGDCAATSTPVSITEPTAPLEVTFDISNISCAGSDDGAIEINATGGTGQIKYAISPQLNQFFDTNVFSNLAAGTYDVIVQDVLGCYVNFSFEITEPVPVILSIVGNSIYPEVCEGDANGEFSVEISGGTLPYSVSLDDYDGTYATGAATQAQFDFTDLSGGDHSVFVRDAQGCESEWNITFPEAVRIESTVAVTYECFDNVTGNVVTVSVDESIDNLEDLDYALNGGPYQASNVFTNLVPGTDHYIEVRHTNGCIQITELFVIEAFDAMTMILEEGELNQIVAVVTGGTGQYEFTLNGESLGNVNTFTVSESGTYTMVVSDGSGCELVASIQMEFVDICIPNYFTPNSDGVSDGWAPGCSSQYTNLEFDIFDRYGRKVATLRQGQLWDGKYKGAELPTGDYWYVVRLNSPDMDRDFVGHFTLYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBW4</accession>
    <name>A0A5C6ZBW4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19065</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000036">
        <property type="protein sequence ID" value="TXD86857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="131" mass="14871" checksum="0083F604E9F5F9AE" modified="2019-11-13" version="1">MKNIFALVLVSAFLTGCGILFPFPESKKFPTTSFYVKNNSTQAINFKASVIKRNSMGPFEMTNAFTVTAKDSVLVRQVSFKRDSESPQNWFNKFTIFPIEGLEMKDPNTAENWFQGVNQNGKPFYTFTIAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC79</accession>
    <name>A0A5C6ZC79_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_18625</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000032">
        <property type="protein sequence ID" value="TXD87006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="92" mass="10830" checksum="FDBFF6072980A460" modified="2019-11-13" version="1" fragment="single">MNIFDFGVHFTDEKSCRTHFKEERDKIGVICNRCQGTQHYWLKNKWSYECKSCSSRQSLRSGTIMQGSKLSFLVWYKTIFLLSTTKKGFSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC97</accession>
    <name>A0A5C6ZC97_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000041">
        <property type="protein sequence ID" value="TXD86724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022674062" evidence="1">
        <location>
            <begin position="26"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="74" mass="8396" checksum="584DB5D7A9734979" modified="2019-11-13" version="1">MNFKISKCLKVVLIVLFFNSITLDAQQANTDFANQMNTIFQNLDKNRLPHGILTDFGLDYVDLLSYGNNIIVSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCE2</accession>
    <name>A0A5C6ZCE2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NAD-dependent epimerase/dehydratase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_16910</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000024">
        <property type="protein sequence ID" value="TXD87459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048040">
        <property type="term" value="F:UDP-glucuronate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042732">
        <property type="term" value="P:D-xylose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044516">
        <property type="entry name" value="UXS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43078">
        <property type="entry name" value="PTHR43078"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="3">
        <location>
            <begin position="5"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD87459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="309" mass="34905" checksum="C9AB7263FDA9D45A" modified="2019-11-13" version="1">MTNFLITGGAGNIGSALASRLAETEDNQITIIDNLSTGHRSKIPQADNVTFINANVNDYNDILPVFGRFDFDYVFHFAAVVGVQRTLEHPVAVLEDIEGIKNVLSISKNSGVKRVFYSSSSEVYGEPFEIPQNENTTPLNSRLPYAIVKNVGEAFFRSYEKEYGMPYTIFRFFNTYGPHQSQDFVVPKFLKAALAGEPLQIHGDGMQTRSFCYIDDTIDTCIKTLEQDYKNTVLNVGNDKEMTVLELANKIIHITGSRSEIEHLPALIEGDMRRRCPDVTKMKTILQRELTSLDEGMQKMIHYYESNDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCI4</accession>
    <name>A0A5C6ZCI4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF4920 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_17495</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000027">
        <property type="protein sequence ID" value="TXD87230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032577">
        <property type="entry name" value="DUF4920"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16267">
        <property type="entry name" value="DUF4920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="172" mass="19002" checksum="E7F24EA73EFDF2DF" modified="2019-11-13" version="1">MKHIIVLVLVVSSLLACKQESKTADVAATEDSQMEQEIAYKSFGKEIDANNAMNTKKMTEAYQNMTVGDSMDAKVMAKVDEVCQAKGCWMKLDLENGEQAMVKFKDYGFFMPKDIAGKEVIINGKAYVNEVPVDEQRHYAEDGGASKEEIALITAPKKTFSFEADGVLLKSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCL5</accession>
    <name>A0A5C6ZCL5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidase_M56 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_16660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000023">
        <property type="protein sequence ID" value="TXD87525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008756">
        <property type="entry name" value="Peptidase_M56"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05569">
        <property type="entry name" value="Peptidase_M56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M56" evidence="1">
        <location>
            <begin position="54"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="589" mass="66869" checksum="7C4BE044BF8ACA41" modified="2019-11-13" version="1">MWLYISGIVFFFGKLCVELFSLRNLLNATQLKSNAGFKLLETSEAITPFSFFNRIVYNPEQFDSEELKHIINHEKVHVSQWHSLDLLIAQICCVLFWFNPFIWGYKRAIQQNLEFIADDVAQGTSEENKAYQTVLLKTCLQTNPFQLTNNFYTSLIKTRILMLHKSKSKRLHKLKLLVILPLLAGFVMSFNTEAIYVETSNPLENPKTRSSLLQDRLTVTFTQDAEESYFAQAKASLAKKGITFTYKDINRNGSNEITAIHVTFKSKTQTTEYKVNGNEPIQPFIFESGADTFKARTLVKGQDIMYDILTDQYNKPITSDSSAVTKAANNTNFIVKEIAKTPTDTTEAKKNEKNTIARPWVLGNTFKIKTVATSALNDSIVYNFSEGVSVTDNDKVISDIISTKTYKPQPLFIIDDKIVSLTEFKRIEPNDIEIMSILKDKATSIYGDKAKYGVIIIETKESHKSKMLAGNHRLNVAEKNANQRSVSLAKVEYIEHEDQLKTIEFIVTKTSSDPFLEKQKNDLKTYGIEAKFSKIKRNDAGEITSLKIALNDNKGRKSSSSWNEKDQAIPDIVMGKSKDDKMFIRAIGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCU4</accession>
    <name>A0A5C6ZCU4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 4">Cryptochrome DASH</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_17310</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">May have a photoreceptor function.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
        </cofactor>
        <text evidence="4">Binds 1 5,10-methenyltetrahydrofolate (MTHF) per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="4">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DNA photolyase class-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000026">
        <property type="protein sequence ID" value="TXD87319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003913">
        <property type="term" value="F:DNA photolyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014133">
        <property type="entry name" value="Cry_DASH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036134">
        <property type="entry name" value="Crypto/Photolyase_FAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036155">
        <property type="entry name" value="Crypto/Photolyase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005101">
        <property type="entry name" value="Cryptochr/Photolyase_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002081">
        <property type="entry name" value="Cryptochrome/DNA_photolyase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006050">
        <property type="entry name" value="DNA_photolyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455">
        <property type="entry name" value="PTHR11455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00875">
        <property type="entry name" value="DNA_photolyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03441">
        <property type="entry name" value="FAD_binding_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00147">
        <property type="entry name" value="DNAPHOTLYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48173">
        <property type="entry name" value="SSF48173"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52425">
        <property type="entry name" value="SSF52425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02765">
        <property type="entry name" value="crypto_DASH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51645">
        <property type="entry name" value="PHR_CRY_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0157">Chromophore</keyword>
    <keyword evidence="3 4" id="KW-0274">FAD</keyword>
    <keyword evidence="2 4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Photolyase/cryptochrome alpha/beta" evidence="5">
        <location>
            <begin position="7"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00017881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD87319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="435" mass="51427" checksum="4180A37630D50C73" modified="2019-11-13" version="1">MQKKQDHIGLVWFRNDLRVEDNSVLRQALDTHTKVIAVYCFDPRHYAETSYGFKKTEKFRAKFLIETIADLKSNLKTLQVELFVFHDQPETAIPKLVADFNVRDIYFQKEWTQEELEVSEALEHELKNKIEFHSRYDQFLYHPDDINMTVDQIPQVYTNFRKKVEKYSQVRTIGSVEAAQSHDINNTTEIPSLNVLGFEDFKAHSNTAIPFKGGETAAMQRLNDYFFETKKLGVYKKTRNGLIGKDFSSKFSIWLANGSISARTIYWKVKQFEKEAFKNDSTYWLIFELIWRDYFKYISLKHGNNLFKIGGILQKDYDWKTDHKQIEKWMRGDTKSDFVNSNMIELNKTGFMSNRGRQNVASYFAKDLLLDWRIGAAYFESLLVDYDVHSNYGNWMYVAGVGNDPRDRKFNVTFQAERYDAEGKYRRLWLQETLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCU8</accession>
    <name>A0A5C6ZCU8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Queuine tRNA-ribosyltransferase</fullName>
            <ecNumber evidence="4">2.4.2.29</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Guanine insertion enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA-guanine transglycosylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">tgt</name>
        <name evidence="6" type="ORF">ESY86_18700</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>7-aminomethyl-7-carbaguanine + guanosine(34) in tRNA = 7-aminomethyl-7-carbaguanosine(34) in tRNA + guanine</text>
            <dbReference type="Rhea" id="RHEA:24104"/>
            <dbReference type="Rhea" id="RHEA-COMP:10341"/>
            <dbReference type="Rhea" id="RHEA-COMP:10342"/>
            <dbReference type="ChEBI" id="CHEBI:16235"/>
            <dbReference type="ChEBI" id="CHEBI:58703"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:82833"/>
            <dbReference type="EC" id="2.4.2.29"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">tRNA modification; tRNA-queuosine biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the queuine tRNA-ribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.29" evidence="4"/>
    <dbReference type="EMBL" id="VORO01000033">
        <property type="protein sequence ID" value="TXD86958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00392"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008479">
        <property type="term" value="F:queuine tRNA-ribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0101030">
        <property type="term" value="P:tRNA-guanine transglycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.105">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00168">
        <property type="entry name" value="Q_tRNA_Tgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004803">
        <property type="entry name" value="TGT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036511">
        <property type="entry name" value="TGT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002616">
        <property type="entry name" value="tRNA_ribo_trans-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01702">
        <property type="entry name" value="TGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51713">
        <property type="entry name" value="SSF51713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00430">
        <property type="entry name" value="Q_tRNA_tgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00449">
        <property type="entry name" value="tgt_general"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4 6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TGT" evidence="5">
        <location>
            <begin position="13"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="92"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="RNA binding" evidence="4">
        <location>
            <begin position="252"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="RNA binding; important for wobble base 34 recognition" evidence="4">
        <location>
            <begin position="276"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="271"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD86958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="376" mass="42728" checksum="818C973ADAD2F655" modified="2019-11-13" version="1">MIFELKAKDAQTKARAGVITTDHGSIETPIFMPVGTVASVKGVHQRELKNDINPDIILGNTYHLYLRPQTHILEKAGGLHKFMNWDRNILTDSGGYQVYSLSANRKIKEEGVKFKSHIDGSTHVFTPENVMEIQRTIGADIIMAFDECTPYPCDYKYAKRSMHMTHRWLDRCIGHLDKLPFKYGYEQTFFPIVQGSTYKDLRQESAEYIANAGAQGNAIGGLSVGEPAEEMYAMTEVVCDILPSEKPRYLMGVGTPINILENIALGVDMFDCVMPTRNARNGMLFTAHGSINIKNLKWADDFSPVDEMGITFVDTEYSKAYLRHLFTVNELLGKQIATIHNLGFYMWLVREARKHIIAGDFRTWKEKMVKQMDKRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD21</accession>
    <name>A0A5C6ZD21_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19785</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000048">
        <property type="protein sequence ID" value="TXD86593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="206" mass="24569" checksum="10FBD88FC9B4777C" modified="2019-11-13" version="1">MIIGTLDLLNYLFDLSKYELSNNENFKKLTFTTKLMINQEIKSVDEEIYKTDTLNFKHNGVFLTLGDRAAITHSHYNKYGSEILNRIMQIQDLLIENNIETNIPEKINPLKIEELVNYEPKPIFIKIKRIDYRYLLNKRDIPMFEAMEKIEEQLKTTSENVSFSFKQTTVFKYIKPIEKKDLVVYELEYDGHPIDENFEYYLTEIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDE8</accession>
    <name>A0A5C6ZDE8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Single-stranded-DNA-specific exonuclease RecJ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">recJ</name>
        <name evidence="9" type="ORF">ESY86_18280</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RecJ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000030">
        <property type="protein sequence ID" value="TXD87088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008409">
        <property type="term" value="F:5'-3' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001667">
        <property type="entry name" value="DDH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038763">
        <property type="entry name" value="DHH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003156">
        <property type="entry name" value="DHHA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004610">
        <property type="entry name" value="RecJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041122">
        <property type="entry name" value="RecJ_OB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01368">
        <property type="entry name" value="DHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02272">
        <property type="entry name" value="DHHA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17768">
        <property type="entry name" value="RecJ_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64182">
        <property type="entry name" value="SSF64182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00644">
        <property type="entry name" value="recJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHH" evidence="6">
        <location>
            <begin position="78"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="DHHA1" evidence="7">
        <location>
            <begin position="315"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="RecJ_OB" evidence="8">
        <location>
            <begin position="452"/>
            <end position="559"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD87088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="561" mass="63049" checksum="6F7CD955624C4FC2" modified="2019-11-13" version="1">MRWTLKPKPKPETIASLQETLQVDATVAILLAQRGIETYEAAKKFFRPSLKDLHDPFLMKDMDRAVERIEKALFNNENIMVYGDYDVDGTTSVALMSSYLKTKSNQIATYIPDRYGEGYGVSYQGIDFAHDNGFSLIIALDCGIKAIDKVNYAAEKGIDFIICDHHRPGAELPKAVAVLDPKRDDCEYPFKELCGCGVGFKLIQALASKDGKTVEDLTEYLDLVATAIGADIVPIVDENRALAYFGLQVINAQPRPGIKAIIEETKKKELTITDVVFIVAPRINAAGRMKHGNYAVTLLTETDEKQAKIYASEINEFNLDRREADRRITEEALVQIIENKEQDRLTSVVYHESWHKGVIGIVASRLTETYYRPTLVFTKSGDKLAASARSVSGFDVYNALEACSVHIEQFGGHKYAAGLTLKQENYEAFKQAFEDEVTKTIDRNLLIPEIKVDFQMKLKDITPKFHRILKQFAPFGPSNMTPIFMSEDLKDSGYGKCVGEDDKHLRLTATQGREKIVCIGFNLGDKCDLITDKKPFNAVYSIDENHWQGNVSLQLKLRDIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDG3</accession>
    <name>A0A5C6ZDG3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Co2+/Mg2+ efflux protein ApaG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">apaG</name>
        <name evidence="2" type="ORF">ESY86_16545</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000023">
        <property type="protein sequence ID" value="TXD87503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007474">
        <property type="entry name" value="ApaG_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036767">
        <property type="entry name" value="ApaG_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04379">
        <property type="entry name" value="DUF525"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110069">
        <property type="entry name" value="SSF110069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51087">
        <property type="entry name" value="APAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ApaG" evidence="1">
        <location>
            <begin position="3"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="128" mass="14139" checksum="D1466E3E7848FD95" modified="2019-11-13" version="1">MVQQVTSGIKISVETTFEGTFYKNYKVHFAFGYRVSIENQSKDSVQLASRYWTILDALNNVETVEGDGVIGQQPVLGPGASHTYSSGCLLTSPFGAMQGHYNMINLNTQDDFKVFIPSFKLSAPYALN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDH1</accession>
    <name>A0A5C6ZDH1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_15775</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="617" mass="70652" checksum="E88B9C306A0BD8EF" modified="2019-11-13" version="1">MIAVTDTSAFAALEIVQPQVQSLIPSENEIETLIGANTFVNATITTAFKNLLKRISLESINPTLGFALQPDLILVKVSQMFNRIGFYYDANSMLSFSTNDNALSAGTEMIIDELNDFTTFQEIAYYAFHNNGWAQNANNIRAMENSGLQKLHYITVFSDSNANSTYNYTPNLNNQINILNLRNENTQRFLLIGFDNATDANPKMPNVRISNNSDVQLKLRVKVEYNKYVTSPQNRLGGFGPAIPYDLNNNGTIATNERIYFNRRFLDYFPNETNATDIEGDIFTRVLQPQSFWDIDCDDRVRGGEVTIDFFPEPENINFWRDGNHHYFKFHIRGKNPTYLQVENYLTNQNYLGRFWFMVRKIRQESGSLGTNDNSEFEQFNALGNYAYSTRKTTFRGLPNFGVPRGYGLSQLDNFGGPLTDTQINNLGLTNELAEIQNGAEREFLTIIDEQNRVIDSTKWIVASDQQVWHWKENIDKAVNFLETEKMTITINEITRIRDRVIAWNNANPTDLVVVPTPEYYNTIIYCWTASAITEFVPYNNLFNQGTAPTIVDQGERELKSFFDAMLLKTYNGIPNQEHFMDINNASSNELVKPVLTIYNTTNPNPFYVRSLSNRDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDH2</accession>
    <name>A0A5C6ZDH2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cell filamentation protein Fic</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_14255</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003812">
        <property type="entry name" value="Fido"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036597">
        <property type="entry name" value="Fido-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02661">
        <property type="entry name" value="Fic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140931">
        <property type="entry name" value="SSF140931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51459">
        <property type="entry name" value="FIDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fido" evidence="1">
        <location>
            <begin position="27"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="183" mass="21517" checksum="C526ABF87A605423" modified="2019-11-13" version="1">MKNIDKKSLEKAYRLFETADIDSIEVGTYKGLQDIHSYLFKNLLDFAGQTRTKNISKGGFRFANALYLNEIILKIETMPETTFDAIISKYVEMNIAHPFMEGNGRTMRIWLDMILKNRLKKVVNWQFVDKALYLQAMERSPINELEIRTILSENLSEDINNRELIFKGIEQSYYYEGYEKDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDM0</accession>
    <name>A0A5C6ZDM0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_15040</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022691240" evidence="1">
        <location>
            <begin position="22"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="Abhydrolase_3" evidence="2">
        <location>
            <begin position="68"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="288" mass="31544" checksum="B4329E76D919CB3A" modified="2019-11-13" version="1">MKHIKITLLALFIAFGFTSCSDNDASPSPENNPDLLYQETLNVSYGNDTDQKFDLYLPANRTLDTKVMIMIHGGGWISGDKADMNFLKDLMRLDLPNIAIVNMNYRLADANNPPIPMQIDDISTVVDMLKAKQDEYVISDDIGFVGVSAGAHLSLLWSYAHDSNSQVKMVGSVVGPTNLTDPAYLESENPYLLQLIEVFGIDTSSAFLESVSPYHQATTSSPPTILFNGGNDPLVPTSQGIDMDAKLSSLGVTHSFTLYPEEGHGWTGAALLDTWISFKAFTKTHLED</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDM6</accession>
    <name>A0A5C6ZDM6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Conjugal transfer protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_17875</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000028">
        <property type="protein sequence ID" value="TXD87183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023220">
        <property type="entry name" value="T4SS_VirB5-domain"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022916624" evidence="2">
        <location>
            <begin position="21"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="45"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="189" mass="21778" checksum="4C1BAB0233B94DCB" modified="2019-11-13" version="1">MKTKFLIFVTVVLLSLKVGAQGMPVYDNTNFISLAKSLIESAKQTSQLLKTVEFLKKQKENLEKVANAIQQLQAVQKIAQNNQQLFNLVQNDLSEILGSPYVNVDEIENITASFTDILDNSLETVNFVEEILSNDYLKMTDSERAEILKQKEMESKQMVSQVKSKTKRYREIISFRKMQDKINNRETEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDT5</accession>
    <name>A0A5C6ZDT5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15625</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023073050" evidence="1">
        <location>
            <begin position="25"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="177" mass="19712" checksum="55BB6F9582EA7F1F" modified="2019-11-13" version="1">MKNQCITSLLSCFVLLLCFNCKDANTKLTANHNTSPKLDDGYAVTVTIQGKAFGIHQKNLESQKATISNDSILFELWEDGNPLKLNFNLFNTDILSKGEATYKIPDANSGQVKVDLNFFNGDRDTKRMNKRILFRKGTISISKISENELKMTFDGEGSGIMEDGKTFPISGKVDVNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE46</accession>
    <name>A0A5C6ZE46_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_15550</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="167" mass="19420" checksum="C520CFB3D3BB49EF" modified="2019-11-13" version="1">MTKKIFFIILLTIVSCKNSRDSESEFMNCVYSKNSESKLTIENTIFEHEVYLKSKGLINGNNGKDYKRLIKDIADEKIAINIIGETLALDVQNLDIDVIGCGEKYSSKDFKAEKLRELFSNMLYKKTDLVKTLNKFNSIVDEEDFKHPFYKICTFVIIDYFILRLNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE61</accession>
    <name>A0A5C6ZE61_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">4Fe-4S dicluster domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_14355</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030948">
        <property type="entry name" value="MoCo_extend_TAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12838">
        <property type="entry name" value="Fer4_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04519">
        <property type="entry name" value="MoCo_extend_TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="1">
        <location>
            <begin position="799"/>
            <end position="829"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1064" mass="116317" checksum="84611E89828E6C2C" modified="2019-11-13" version="1">MSSNKKYWKSVEELNENSSIVETLKQNEFVSEIPTEEFLGNKKSLESSSTTRRDFLKYVGFSTAAASLAACEGPVVKSIPYVVQPEEIIPGVANYYATTIANGFDFASILIKTREGRPIKIENNTLAKTQGSANARVNASVLDLYDNMRVKSAMKDGAPITWETFDAETNVALSSIKNSGKDIVLLTQTFASPSTSKLIAEFQSKYGNVRHVVYDAVSESAALDAFEAKYGTRGLATYDFEKAMTIVSVGADFLGDWQGGGFDAGYAKGRVPKNGRMSRHIQFESNMSLTGANADKRVPVTPSQQKQVLARLYSLITGGSAATDLPENIDQAVQKAASALKKAGSNGVLATGINDVNAQTLALAINSALSSKAFDPSTPILTRQGSNKAVSQLVTDMLAGKVGGIIMSGVNPLYTLPNALDFAEGLKKTELSIAFSQKADESALAAQYIAAAPHYLESWGDVELKKGHFSLMQPTIRPLFDTRQFQQALLLWNGSDMSFREYIKTNWDGGILGGNSFNKALQDGVYVPGFMGASPGSASTQTNEISGTDLKDENDSTVVGVGISDEDQATNETANGMSIGTIGSAARDLVSSAKAEGMELSLYTKVGMGDGQQANNPWLQEFPDPITRTSWDNYVTVSRADAEKLGFEHSNDATGGLNGNYAELTVNGITVKNIPVIIQPGQAKGSLGLSFGYGRTAGLKDEMKTGVNAYPLYQDFNTTQNVSIKKEAGIHEFACVQLQNTLMGRGDIIKDTTLEIFNTRERQYWNPMAMVSLNHEETPVTSPKVDLWDEFDRSMGHHFNLAIDLNACTGCGACVIACHAENNVPVVGKEEIRRSRDMHWLRIDRYYSSEDTFTEDVTKKEDTKGLSIIDAYDEMEHAADNPQVAFQPVMCQHCNHAPCETVCPVAATVHGRQGQNQMVYNRCVGTRYCGNNCPYKVRRFNWFLYNKNDEFDYHMNDDLGRMVLNPDVTVRSRGVMEKCSMCIQMTQKTILDAKRDGRVIEDGEFHTACSAACSSGAIKFGDINDEESVVAKLKEDDRMYHLLEHVGTKPNVQYHVKVRNTTEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE66</accession>
    <name>A0A5C6ZE66_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_13555</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="99" mass="11439" checksum="94B61B4B4C199644" modified="2019-11-13" version="1">MTSEKSYGNSTMPCFDPHFAIVYYLQEKRVGTISICLECNYLIASEKIPATELKIIEISDEYSYPAKGFSKATRKEIYDYIKHIGFTKYLKPLTSYLDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEG1</accession>
    <name>A0A5C6ZEG1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4271 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_13950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025367">
        <property type="entry name" value="DUF4271"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14093">
        <property type="entry name" value="DUF4271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="191"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="217" mass="24821" checksum="56249EF1578C8385" modified="2019-11-13" version="1">MLREVVSNDWFTIALTVGLVAVALSKYLFAHRYSDFISVLGNSKYLKIYSRDQKFIDGFDALYFVNFIISVAIFAYVCYSTLVHPSAFDLDQFFKLLFGVGVLFLSKVLLERLIGSLFEIDTIIDSYLFQKTTFKNYTGFILLPVNCILIYTLTPSKSLIYGILIVIVIINLVGFISTFKMYQKLLLNNIFYFILYLCALEIGPYLILSKLIIDSNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEG4</accession>
    <name>A0A5C6ZEG4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="9 10">Protein translocase subunit SecY</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9 13" type="primary">secY</name>
        <name evidence="13" type="ORF">ESY86_14930</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1 11">Membrane</location>
            <topology evidence="1 11">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 12">Belongs to the SecY/SEC61-alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043952">
        <property type="term" value="P:protein transport by the Sec complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01465">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026593">
        <property type="entry name" value="SecY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002208">
        <property type="entry name" value="SecY/SEC61-alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030659">
        <property type="entry name" value="SecY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023201">
        <property type="entry name" value="SecY_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10906">
        <property type="entry name" value="PTHR10906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00344">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004557">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103491">
        <property type="entry name" value="SSF103491"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00967">
        <property type="entry name" value="3a0501s007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00755">
        <property type="entry name" value="SECY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00756">
        <property type="entry name" value="SECY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9 11" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9 11" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9 11" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="72"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="155"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="181"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="218"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="273"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="315"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="376"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="401"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TXD87961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="450" mass="48628" checksum="7373EFDC91532341" modified="2019-11-13" version="1">MKFIDTLKNVWKITELKDRIILTLGLLLVYRFGAQVVLPGIDASQLGGLAQGTDQGILGILNMFTGGAFANASVFALGIMPYISASIVVQLMGIAIPYLQKLQKEGASGQKKITQITRWLTIIICLFQAPGYLASLQPAFGIPTSAFLLGTGPTFYISGVIILVTGTIFAMWLGEKITDKGIGNGISLLIMVGIIATLPQSFIQNAASRLDGGGNGGLMMILIELVVWFVIIMASVLLVMAVRKIAVQYARRTASGGYEKNVFGSRQFLPLKLNASGVMPIIFAQAIMFVPSLIGKSFGSSSEVGQWIQAQFTDIFGLWYNVVFALLIIIFTYFYTAITVPTNKMADDLKRSGGFIPGIRPGSETSEYLDKIMSQITLPGSIFLALIAVFPAIIVKLMDVQAGWALFFGGTSLLIMVGVAIDTMQQINSYLLNKHYDGLMKTGKNRKAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEH3</accession>
    <name>A0A5C6ZEH3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000029">
        <property type="protein sequence ID" value="TXD87125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017507">
        <property type="entry name" value="Tscrpt_reg_HipB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03070">
        <property type="entry name" value="couple_hipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="10"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="69" mass="7707" checksum="39A6A2D3D5158B3D" modified="2019-11-13" version="1">MNDLDLGAFIKDHRKNAGLTQLELADLAGIGKTTVFDIEKNKETVRFNNLLAVLHVLNINVEFKSPLTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEM2</accession>
    <name>A0A5C6ZEM2_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Tyrosine recombinase XerC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">xerC</name>
        <name evidence="13" type="ORF">ESY86_16250</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the 'phage' integrase family. XerC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009037">
        <property type="term" value="F:tyrosine-based site-specific recombinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01808">
        <property type="entry name" value="Recomb_XerC_XerD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004107">
        <property type="entry name" value="Integrase_SAM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023009">
        <property type="entry name" value="Tyrosine_recombinase_XerC/XerD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02899">
        <property type="entry name" value="Phage_int_SAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 9" id="KW-0132">Cell division</keyword>
    <keyword evidence="4 9" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="2 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0229">DNA integration</keyword>
    <keyword evidence="7 9" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6 9 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="12">
        <location>
            <begin position="1"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="11">
        <location>
            <begin position="105"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="170"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="240"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="243"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="266"/>
        </location>
    </feature>
    <feature type="active site" description="O-(3'-phospho-DNA)-tyrosine intermediate" evidence="9">
        <location>
            <position position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TXD87588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="296" mass="33845" checksum="3AE873F7E924A98F" modified="2019-11-13" version="1">MSISAFSDYLLFEKKYSELTLKAYRSDLEGFSEFIASEYETSSIDDVNYPQIRNWIVKLVDSGISNRSINRKISSLNSYYKFLQKIGELQINPLSKHRALKTGKKVQVPFSEKEMASVLELLDGDTSFEGLRNRAIIELFYATGIRRIELVQLKLRDLDLQAATVKILGKRNKERLMPLLPSVVASLNRYILARNNCEIIEDPDLLFLTKKGVKIYEMLVYRIINDYFSLVSSKVKRSPHILRHSFATHLLNQGANLNAVKELLGHSSLAATQVYTHNSIAKLKEVYAKAHPRSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEP7</accession>
    <name>A0A5C6ZEP7_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Biotin carboxylase</fullName>
            <ecNumber evidence="5">6.3.4.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Acetyl-coenzyme A carboxylase biotin carboxylase subunit A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">accC</name>
        <name evidence="8" type="ORF">ESY86_13030</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + hydrogencarbonate + N(6)-biotinyl-L-lysyl-[protein] = ADP + H(+) + N(6)-carboxybiotinyl-L-lysyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13501"/>
            <dbReference type="Rhea" id="RHEA-COMP:10505"/>
            <dbReference type="Rhea" id="RHEA-COMP:10506"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83144"/>
            <dbReference type="ChEBI" id="CHEBI:83145"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.14"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.14" evidence="5"/>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00655">
        <property type="reaction ID" value="UER00711"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004075">
        <property type="term" value="F:biotin carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001295">
        <property type="term" value="P:malonyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004549">
        <property type="entry name" value="Acetyl_CoA_COase_biotin_COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CbamoylP_synth_lsu-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00289">
        <property type="entry name" value="Biotin_carb_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00878">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00514">
        <property type="entry name" value="accC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0092">Biotin</keyword>
    <keyword evidence="5" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="1 5 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="2 4 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin carboxylation" evidence="7">
        <location>
            <begin position="1"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="6">
        <location>
            <begin position="120"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU365063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD88435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="451" mass="50097" checksum="0985AC2544C8A3C7" modified="2019-11-13" version="1">MFKKILIANRGEIALRVIRTCKEMGIKTVAVYSTADAESLHVKFADEAVCIGPPASSESYLKIPNVIAAAEITNADAIHPGYGFLSENAKFSKICEEHGIKFIGASADMISKMGDKATAKATMREAGVPCVPGSEGIISDFEHCEKLAEEVGYPVMLKATAGGGGKGMRAVWKHEKLKDAWDSARQESKAAFGNNDMYMEKLIEEPRHIEIQIVGDSTGKACHLSERDCSIQRRHQKLTEEVPSPFMTKALRDKMGKAAVKAAEYIGYEGAGTVEFLVDKHRNFFFMEMNTRIQVEHPITEQVIDFDLIREQILVAAGVPISGKNYLPQMHAIECRINAEDPFNDFRPSPGRITTLHAPGGHGVRLDTHVYAGYVIPPNYDSMIAKLITTAQTRLEAINKMKRALDEFVIEGIKTTIPFHRQLMDHPDYLAGNYTTKFMEDFVIEKPKDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF04</accession>
    <name>A0A5C6ZF04_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_11685</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022847271" evidence="2">
        <location>
            <begin position="20"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="58"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="242" mass="27128" checksum="65DA5EA303306A69" modified="2019-11-13" version="1">MKTVRFLVLLLGVAWQSFAQQPDNNEKKALKIPAIETDIKDSIPAAFEIKPESKFSIRNPEKSNSGNAPKNKITIKSPEKEFSMIDDNPLMQPGAIYEQRFNKVAVEQGLMIETMADVFLGDIRSNGEFVKIMCRDHEYPDGDLVQVIVNDVTIIPRLLLESGFKGFDIPLEVGINKIVFLALNQGESGPNTAEFIVYDDNQRLVSSKKWNLLTGVKATILVIKDEYPILEKGAQETNSKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF05</accession>
    <name>A0A5C6ZF05_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF2256 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_17305</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000026">
        <property type="protein sequence ID" value="TXD87350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017136">
        <property type="entry name" value="UCP037205"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37463">
        <property type="entry name" value="PTHR37463"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10013">
        <property type="entry name" value="DUF2256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037205">
        <property type="entry name" value="UCP037205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="49" mass="5929" checksum="989DD1DAEE9C8D0B" modified="2019-11-13" version="1">MKNTKKQHLPQKTCPVCGLPFTWRKKWEKNWDSVKYCSEKCRRNKTTSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF06</accession>
    <name>A0A5C6ZF06_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Pyruvate dehydrogenase E1 component subunit alpha</fullName>
            <ecNumber evidence="2 7">1.2.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">pdhA</name>
        <name evidence="9" type="ORF">ESY86_12600</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>(R)-N(6)-lipoyl-L-lysyl-[dihydrolipoyllysine-residue acetyltransferase] + H(+) + pyruvate = (R)-N(6)-(S(8)-acetyldihydrolipoyl)-L-lysyl-[dihydrolipoyllysine-residue acetyltransferase] + CO2</text>
            <dbReference type="Rhea" id="RHEA:19189"/>
            <dbReference type="Rhea" id="RHEA-COMP:10480"/>
            <dbReference type="Rhea" id="RHEA-COMP:10481"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83111"/>
            <dbReference type="EC" id="1.2.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="7">Heterodimer of an alpha and a beta chain.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.4.1" evidence="2 7"/>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043231">
        <property type="term" value="C:intracellular membrane-bounded organelle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004739">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006086">
        <property type="term" value="P:acetyl-CoA biosynthetic process from pyruvate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017597">
        <property type="entry name" value="Pyrv_DH_E1_asu_subgrp-y"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03182">
        <property type="entry name" value="PDH_E1_alph_y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 7 9" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="E1_dh" evidence="8">
        <location>
            <begin position="15"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD88573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="332" mass="37781" checksum="5BE0DD824CBB1256" modified="2019-11-13" version="1">MQKVTKEVYLKWYEDMYFWRKFEDKLAQVYLKQKVRGFLHLYNGQEAVLAGALHAMDLTKDKMITAYRNHVQPIGMGVDPKRVMAELYGKATGTSQGLGGSMHIFSKEFRFYGGHGIVGGQIPLGAGIAFGDKYHDKDAVTLCCFGDGAARQGSLHETFNLAMLWKLPVVFVCENNGYAMGTSVARTANHTDIWKLGLGYEMPCGPVDGMNPVKVAEAFDEAIERARRGDGPTFLEMKTYRYRGHSMSDAQHYRTKDEVKEYEKVDPITQVKDIILEEKYATEDELAAIDKRVKKRVVECEKFADESPFPEKSVMYDVVYEQEDYPFIEHKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF96</accession>
    <name>A0A5C6ZF96_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD-dependent monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="1">
        <location>
            <begin position="88"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="485" mass="53035" checksum="8B2B7D4C1881E3D5" modified="2019-11-13" version="1">MKTLEHEAASWTSCLDCQGRGKKSRRLRKKVRLNYQRSLEHYQKSNGKGRAPIRPKGHLYTCLNCSGSGLIPSPSAPIPDTENYPHLAIIGGGIGGVALAVACLHRKIPFTLYERDTNFDVRSQGYGLTLQQASKAIEGLGVFTLEEGVVSTRHLMHTTAGKVIGEWGMRKWIQQDDNSAPKRTNVHIARQSLRLALLEQLGTQDVVQWGHQLVGFTEDEGQGVDLRFQVDGEIKNAKADLVVGADGIRSSVRSLLLGEASTPLRYLGCIVILGICPLAGLEGLESSLLDSATVFQTANGHERIYMMPYTSNSIMWQLSFPMLEKEAKALSAQGAQALKAEACRRTQWHDPIPQILAATQETQVSGYPVYDRELLSSELLETAGAVTLIGDAAHPMSPFKGQGANQALLDALALARGIYSGCRPQSQWREAGLRKSVLTAFETEMIARSTPKVEASAEAAQFLHSDIVLHEGDEPRGRCIKRKDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFC8</accession>
    <name>A0A5C6ZFC8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">(2Fe-2S)-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_13275</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002888">
        <property type="entry name" value="2Fe-2S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036884">
        <property type="entry name" value="2Fe-2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01799">
        <property type="entry name" value="Fer2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47741">
        <property type="entry name" value="SSF47741"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="2">
        <location>
            <begin position="2"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="153" mass="16458" checksum="F205845487D5F5D7" modified="2019-11-13" version="1">MAEFSININGENHNVNVDPSTPLLWVLRDHLKMVGTKYGCGIAQCGACTVHFNGTAVRSCQLPVSAAVDNMITTIEGLSEHGDHPVQKAWLEHDVPQCGYCQAGQIMTASALLKQNPNPSDKDIDNAMSGNICRCGTYTRIKAAIKTASDSQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFI1</accession>
    <name>A0A5C6ZFI1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">FMN-binding glutamate synthase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_15025</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glutamate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015930">
        <property type="term" value="F:glutamate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006537">
        <property type="term" value="P:glutamate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02808">
        <property type="entry name" value="GltS_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024188">
        <property type="entry name" value="GltB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002932">
        <property type="entry name" value="Glu_synthdom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01645">
        <property type="entry name" value="Glu_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006429">
        <property type="entry name" value="GOGAT_lg_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="Glu_synthase" evidence="4">
        <location>
            <begin position="144"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR006429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD87980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="533" mass="59340" checksum="8572F59B918209DB" modified="2019-11-13" version="1">MDTVLDFISRISWWQWILIVIVIVAIRDVLQRSHSISHNFPIVGHFRYWLESIGPELRQYLVANNREELPFNRIERGWVYASSKDENNYEGFGTDRDIYAHQHIFVNNAMFPYKIGENHPNTIDKTFLPCAKVMGIYHKRAKPYRPGSVINVSAMSFGSLSAKAIESLNKGVKIAGAYHNTGEGGLSPYHKHGGDVVFHFGTGYFGVRGKDGKFSMEKMKQLVIDNPFIKAIEIKLSQGAKPGKGGVLPGSKISKEIAEIRGVEVGKTVLSPPNHSAFSTVPEMVALIEAIAKETGLPVGIKAAIGKLEQWEELADYMVKTDTGPDFLTIDGGEGGTGAAPPSFADHVSLPWTYAFEDIYELFKRKELCERIVFIGSGKLGFPAKAAMAFAMGADCINVAREAMMSIGCIQAQICHTNRCPSGVATQNQWLQRGINVPLKSERMAQYFKTFRKELIEITHATGYEHPCQFNMADIEMNVDDHNLSKKLRNAYHYSKVPVDFESMQALKDCTYLGGKPFDPDSEEVEGDNTLNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFL6</accession>
    <name>A0A5C6ZFL6_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA topoisomerase (ATP-hydrolyzing)</fullName>
            <ecNumber evidence="2">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_11855</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.268.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.199.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013758">
        <property type="entry name" value="Topo_IIA_A/C_ab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013757">
        <property type="entry name" value="Topo_IIA_A_a_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002205">
        <property type="entry name" value="Topo_IIA_dom_A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00521">
        <property type="entry name" value="DNA_topoisoIV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00434">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56719">
        <property type="entry name" value="SSF56719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="TOP4c" evidence="7">
        <location>
            <begin position="21"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="841"/>
            <end position="895"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="420"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="842"/>
            <end position="857"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD88654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="895" mass="101735" checksum="BD5E76271C305CB2" modified="2019-11-13" version="1">MSEEIDDLANEQNEQPQESITRVTGMYKDWFLDYASYVILERAVPAIEDGFKPVQRRIMHSMKDLDDGRYNKVANIVGHTMQYHPHGDASIADAMVQIGQKDLLIDTQGNWGNILTGDRAAASRYIEARLSKFALEVVYNPKITGWQSSYDGRRKEPINLPVMFPLLLAQGGEGIAVGLSTKILPHNFIELIDASVKHLNGKRFTIVPDFPTAGIADVTDYKDGLRGGKIRVRAKISQLDRNTLVITEIPFGTNTTSLIDSILKANEKGKIKIKKIDDNTAAEVEILVHLPAGISPEKTIDALYAFTSCENSISPLGCVIEDNKPLFVGVTEMLRRSTDNTVQLLKSELEIRLGEFEEQWHFASLERIFIEKRIYRDIEEEETWEGVINAIDKGLKPHIAHLKRAITQEDIERLTEIRIKRISKFDIDKAQQKIDALEDQIAQVKHHLAHLIDYAIAYFERLKKEYGKGRERKTEIRIFEDVDASKVIIRNTKLYVNRAEGFIGTSLKRDEYVGDCSDIDDIIVFTGEGKMMVTKVDSKTFIGKDIVHVAVFKKKDKRTIYNMIYRHGSKGATYVKRFSITAITRDKEYDLTKDAKGSKMWYFSANPNGEAEVVTVYLRQVGSIKKLKWDLDFAEVLIKGRNSKGNMVTKHAIKKIELKERGVSTLKPRKIWFDDTVQRLNVDDRGWLIGEFRGEDRLLVISQKGVLKTILPELTAHFEDDMIVLEKWNPKKPISAIYYNGEKELYYVKRFLIETEGKEELFISEHANSQLEIVSTDWKPVVDIEFKKERGKERKDNESVNIEEFIAIKGISALGNQLTKEKVNQISLLDPLPYEAPEETHAEDLEVVDETEVDSNSDDASEGNSAKDTTATMKPDDAEDSEDSDLDGEGQTTLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFT9</accession>
    <name>A0A5C6ZFT9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 10">1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase</fullName>
            <ecNumber evidence="8 10">5.3.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">hisA</name>
        <name evidence="11" type="ORF">ESY86_10470</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8 10">
            <text>1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide = 5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:15469"/>
            <dbReference type="ChEBI" id="CHEBI:58435"/>
            <dbReference type="ChEBI" id="CHEBI:58525"/>
            <dbReference type="EC" id="5.3.1.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 8 10">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 4/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 8 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 8 9">Belongs to the HisA/HisF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.16" evidence="8 10"/>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00009"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003949">
        <property type="term" value="F:1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04732">
        <property type="entry name" value="HisA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01014">
        <property type="entry name" value="HisA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006062">
        <property type="entry name" value="His_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006063">
        <property type="entry name" value="HisA_bact_arch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044524">
        <property type="entry name" value="Isoase_HisA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023016">
        <property type="entry name" value="Isoase_HisA-like_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43090">
        <property type="entry name" value="PTHR43090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00977">
        <property type="entry name" value="His_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00007">
        <property type="entry name" value="TIGR00007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8 9" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="7 8 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="8"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD88913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="238" mass="26023" checksum="BE23A1A539F09C71" modified="2019-11-13" version="1">MRIIPAIDIIDGKCVRLTKGDYDTKKIYNENPVEVAKKFEAAGIEYLHLVDLDGAKANHIVNYKVLELIASKTTLKIDFGGGLKSNEDLHIAFNCGAKQITGGSIAVKDSNTFEAWLSKYGGTKIILGADCHKEKIAVNGWQEESDMEVLPFIKSYVSKGIQYVICTDIAKDGMLEGPSFELYKKILSESKDIKLIASGGITSIEDLNKLEDLGCEAAIIGKALYEGHIALKDLELHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFV0</accession>
    <name>A0A5C6ZFV0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_12185</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="76" mass="9210" checksum="1787FED156EAF4F4" modified="2019-11-13" version="1">MELPKYILGDNTDLPNAIFVIHTEFPRFVINLEDDEVEWLEEFDQHDEKEIENEMENLIQEATAFYDREVSRYDEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFV9</accession>
    <name>A0A5C6ZFV9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2141 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12245</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018673">
        <property type="entry name" value="DUF2141"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09912">
        <property type="entry name" value="DUF2141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023102530" evidence="1">
        <location>
            <begin position="21"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="141" mass="15526" checksum="78A24A86C13F8178" modified="2019-11-13" version="1">MSTLAKIFIFAILSQTFSNAQEPNLKSITVKIQNLSSNQGMVYVALYNAEATFLGKGIQSSKTMVSNKSCEVVFKNLPEGVYAVSFFHDENGNGKLDTNFMGIPKETYGCSNNAQGFMGPPKWSDAKFEMSNENIEQTITL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGA5</accession>
    <name>A0A5C6ZGA5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DegT/DnrJ/EryC1/StrS family aminotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_10135</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the DegT/DnrJ/EryC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00616">
        <property type="entry name" value="AHBA_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000653">
        <property type="entry name" value="DegT/StrS_aminotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30244">
        <property type="entry name" value="PTHR30244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01041">
        <property type="entry name" value="DegT_DnrJ_EryC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000390">
        <property type="entry name" value="PLP_StrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="198"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="374" mass="41279" checksum="82F6FBB5F4627C9D" modified="2019-11-13" version="1">MIPFLDLHKINARFEDAFTAKFKSFLDSGHYILGQEVETFEQNLANYCGSRHCIGVANGLDALTLIFKAYLQLGKLAEGDEVLVPSNTYIASILAVINAGLKPVFVEPDAQTFNMAPSEIEKHISPKTKVILVVHLYGQLADMDVINRIAKEQDLLVVEDAAQAHGAVANSKNEIPNSKMEKAGNLGNAAGFSFYPSKNLGALGDAGAITTNDGALAIALRLLRNYGSSKKYVNSTLGVNSRLDELQAAFLNIKLKQLDADNERRRAIAKRYSSEVKNEKISLPFYDGSNNHVFHLYVIQVEDRAHFIKHLETEGIGYLIHYPIAPHQQEALSAYQHLSLPIAEKLQQTVLSLPMSPVMSEIEIETVIASINRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGB2</accession>
    <name>A0A5C6ZGB2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">WxcM-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20292">
        <property type="entry name" value="cupin_QdtA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008894">
        <property type="entry name" value="QdtA_cupin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05523">
        <property type="entry name" value="FdtA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FdtA" evidence="1">
        <location>
            <begin position="8"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="138" mass="15842" checksum="658F5447CAED2AB5" modified="2019-11-13" version="1">MKTTLKHIKFVGIPNVHDQRGKLAVIEKHVIPFKMQRIYYLFDVPSDAYRGGHAHKIQESVVIALSGSFEVVIKDGKDEQRIMLNKPDKGLYIPTGIWREIENFSSGSVCLVLASTEFEEADYIRDYEEFLLSKRAKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGF3</accession>
    <name>A0A5C6ZGF3_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Probable membrane transporter protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_13335</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002781">
        <property type="entry name" value="TM_pro_TauE-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01925">
        <property type="entry name" value="TauE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="71"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="136"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="198"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="228"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD88287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="251" mass="27172" checksum="E35FA08269DF1FEE" modified="2019-11-13" version="1">MPIEYLPFIFFFIALFYSSVGFGGGSSYLAILSLVLTDFYEIRSTALILNICVVTIGTIVYMKHGVLKPKLLWPFFVLSIPMAYLGALVKLSQDSFFLVLGCALLLAGIFMLLKLVQSRLESVEFSNPKKLLLGGSIGLLSGISGIGGGIFLSPVLNLLKWENPRIIAALASVFILVNSLAGLVGLNVAGTFRLDYDLVFNLIIAVVLGGSLGSYLSNKKFNLKILGILTAILVFYVGLRLILLHGFGIKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGK5</accession>
    <name>A0A5C6ZGK5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptide chain release factor 3</fullName>
            <shortName evidence="5">RF-3</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">prfC</name>
        <name evidence="7" type="ORF">ESY86_12980</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF-1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. PrfC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016149">
        <property type="term" value="F:translation release factor activity, codon specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006449">
        <property type="term" value="P:regulation of translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04169">
        <property type="entry name" value="RF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00072">
        <property type="entry name" value="Rel_fac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004548">
        <property type="entry name" value="PrfC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032090">
        <property type="entry name" value="RF3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038467">
        <property type="entry name" value="RF3_dom_3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041732">
        <property type="entry name" value="RF3_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43556">
        <property type="entry name" value="PTHR43556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16658">
        <property type="entry name" value="RF3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00503">
        <property type="entry name" value="prfC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="6">
        <location>
            <begin position="8"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="17"/>
            <end position="24"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="85"/>
            <end position="89"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="139"/>
            <end position="142"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD88426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="532" mass="60711" checksum="FCE6AEBBC19C8848" modified="2019-11-13" version="1">MSFKSEINRRRTFGIISHPDAGKTTLTEKLLLFGGAIQEAGAVKSNKIKKGATSDFMEIERQRGISVATSVLAFEYDGIKINILDTPGHKDFAEDTFRTLTAVDSVIVVIDVAKGVEQQTEKLVEVCRMRNIPMIVFINKMDREGKDAFDLLDEIEQKLGLNVVPLSFPIGMGYDFKGIYNLWEQNINLFSGSSRKNIEETIEISDLKSEKLDTLLGTKAAKTLREEIELVEGIYPKFNREAYLKSEQQPVFFGSALNNFGVRELLDCFVEIAPKPRPKRSEERLVNPDEKEFTGFVFKIHANMDPNHRDRLAFVKIVSGEFKRNTPYLHVRNDKKMKFSSPNAFFAEKKEIVDISYPGDIVGLHDTGNFKIGDTLTEGETINYKGVPSFSPEHFRYINNADPMKSKQLNKGIDQLMDEGVAQLFTLELNGRKVIGTVGALQYEVIQYRLEHEYGAKCTYENLNVHKACWVEAKDSKSEEFLEFLRVKQRFLAKDKQDQLVFLADSPFSLQMTQQKYPNIKFHFTSEFEDAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGR2</accession>
    <name>A0A5C6ZGR2_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">6-carboxy-5,6,7,8-tetrahydropterin synthase</fullName>
            <ecNumber evidence="8">4.-.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">ESY86_12990</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>7,8-dihydroneopterin 3'-triphosphate + H2O = 6-carboxy-5,6,7,8-tetrahydropterin + acetaldehyde + 2 H(+) + triphosphate</text>
            <dbReference type="Rhea" id="RHEA:27966"/>
            <dbReference type="ChEBI" id="CHEBI:15343"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18036"/>
            <dbReference type="ChEBI" id="CHEBI:58462"/>
            <dbReference type="ChEBI" id="CHEBI:61032"/>
            <dbReference type="EC" id="4.1.2.50"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8 10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8 10">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Purine metabolism; 7-cyano-7-deazaguanine biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the PTPS family. QueD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.-.-.-" evidence="8"/>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00391"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070497">
        <property type="term" value="F:6-carboxy-5,6,7,8-tetrahydropterin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007115">
        <property type="entry name" value="6-PTP_synth/QueD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038418">
        <property type="entry name" value="6-PTP_synth/QueD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12589">
        <property type="entry name" value="PTHR12589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01242">
        <property type="entry name" value="PTPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006113">
        <property type="entry name" value="PTP_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 8 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 10" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="34"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="9">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="9">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR006113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR006113-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR006113-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD88428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="136" mass="15654" checksum="67117DA9BB1EAD92" modified="2019-11-13" version="1">MKVTVSRKAHFNAAHRLYREDWSFEKNDAVFGKCNNPNFHGHNYELVVHVTGEIDPETGFVMDMKVLKDLIKAEIEDAFDHKNLNVEVPEFKELNPTAENIAVVIYQKLKPKLEASVDLEITLYETPRNFVSYSGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGW0</accession>
    <name>A0A5C6ZGW0_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Thiamine-monophosphate kinase</fullName>
            <shortName evidence="2">TMP kinase</shortName>
            <shortName evidence="2">Thiamine-phosphate kinase</shortName>
            <ecNumber evidence="2">2.7.4.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2 5" type="primary">thiL</name>
        <name evidence="5" type="ORF">ESY86_08270</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the ATP-dependent phosphorylation of thiamine-monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + thiamine phosphate = ADP + thiamine diphosphate</text>
            <dbReference type="Rhea" id="RHEA:15913"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37575"/>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; thiamine diphosphate biosynthesis; thiamine diphosphate from thiamine phosphate: step 1/1.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="2">Reaction mechanism of ThiL seems to utilize a direct, inline transfer of the gamma-phosphate of ATP to TMP rather than a phosphorylated enzyme intermediate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the thiamine-monophosphate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.16" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00060">
        <property type="reaction ID" value="UER00142"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009030">
        <property type="term" value="F:thiamine-phosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02194">
        <property type="entry name" value="ThiL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.650.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02128">
        <property type="entry name" value="TMP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010918">
        <property type="entry name" value="PurM-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036676">
        <property type="entry name" value="PurM-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016188">
        <property type="entry name" value="PurM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036921">
        <property type="entry name" value="PurM-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006283">
        <property type="entry name" value="ThiL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30270">
        <property type="entry name" value="PTHR30270"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00586">
        <property type="entry name" value="AIRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02769">
        <property type="entry name" value="AIRS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005303">
        <property type="entry name" value="Thiam_monoph_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55326">
        <property type="entry name" value="SSF55326"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56042">
        <property type="entry name" value="SSF56042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01379">
        <property type="entry name" value="thiL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AIRS" evidence="3">
        <location>
            <begin position="41"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="AIRS_C" evidence="4">
        <location>
            <begin position="165"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="42"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>4</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="87"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="134"/>
            <end position="135"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="240"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>5</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="291"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="343"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD89375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="349" mass="38336" checksum="C2E5888C22DF401E" modified="2019-11-13" version="1">MIEDKNPQRTPLEQLGEFGLIDHLTKNFKIKKSSSIKGIGDDAAVLDFKDKQVVVTTDLLVENVHFDLSYMPLKHLGYKAVVVNLSDVYAMNATATQITVSIAVSNRFPLEALEALYAGIETAASIYDIDVVGGDTTSSTTGLLISVTAIGEVDKDDVVYRNGAKPNDLVVLTGDIGAAYMGLQVLEREKEVFKVNPENQPDLDAYTYIIERQLKPEARKDIVELLKDLEVKPTAMMDVSDGLSSEIIHICKQSKVGVELYESKIPLDPEVISVCEEFKIDSTTIALNGGEDYELLMTIAQEDFEKIKGNPNLTVIGFITEEARGMNLITRGEQVIPIIAKGWNALGDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGZ9</accession>
    <name>A0A5C6ZGZ9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">N5-carboxyaminoimidazole ribonucleotide synthase</fullName>
            <shortName evidence="3 5">N5-CAIR synthase</shortName>
            <ecNumber evidence="3 5">6.3.4.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3 5">5-(carboxyamino)imidazole ribonucleotide synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">purK</name>
        <name evidence="7" type="ORF">ESY86_12465</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).</text>
    </comment>
    <comment type="function">
        <text evidence="5">Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)- to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 5">
            <text>5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + ATP + hydrogencarbonate = 5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + ADP + 2 H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19317"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58730"/>
            <dbReference type="ChEBI" id="CHEBI:137981"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 5">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (N5-CAIR route): step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the PurK/PurT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.18" evidence="3 5"/>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00942"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034028">
        <property type="term" value="F:5-(carboxyamino)imidazole ribonucleotide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004638">
        <property type="term" value="F:phosphoribosylaminoimidazole carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01928">
        <property type="entry name" value="PurK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003135">
        <property type="entry name" value="ATP-grasp_carboxylate-amine"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005875">
        <property type="entry name" value="PurK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040686">
        <property type="entry name" value="PurK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02222">
        <property type="entry name" value="ATP-grasp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17769">
        <property type="entry name" value="PurK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01161">
        <property type="entry name" value="purK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 4 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 3 5" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="6">
        <location>
            <begin position="112"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="181"/>
            <end position="184"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="268"/>
            <end position="269"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU361200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD88546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="385" mass="43200" checksum="C2999C2E2D2E94E8" modified="2019-11-13" version="1">MTNYFSSDFKLGILGGGQLGKMMLYSTRKFDICTYVMDGSDEAPCKIACNKFVKGELMDFDAVYNFGKTVDLLTFEIENVNVDALEKLEQEGVKVYPSSKTLRLIQNKATQKLFYRDHSIPTADFNRFAYLSEIDESIENGGLEFPFVWKATQFGYDGKGVKIVRNLEDLKELPKGECITEKLIPFKNELAVIVARNEAGEVKTYPVVEMEFHPEANQVEYVICPARISDAVADKARTTAMVVSEAFNHVGLLAVELFQTEDDDILVNEVAPRPHNSGHQTIEASYTSQFEQHLRAILNLPLGKTESKAAGVMVNLVGAEGHTGDVVYEHIADIMKMEGVTPHIYGKKQTRPFRKMGHVTIVNNDITEARRIAEDVKRTIRVVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH20</accession>
    <name>A0A5C6ZH20_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methylmalonyl Co-A mutase-associated GTPase MeaB</fullName>
            <ecNumber evidence="2">3.6.5.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">meaB</name>
        <name evidence="2" type="ORF">ESY86_12145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.-" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005129">
        <property type="entry name" value="GTPase_ArgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23408">
        <property type="entry name" value="PTHR23408"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00750">
        <property type="entry name" value="lao"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="359" mass="39153" checksum="BCE2221134C2C3A9" modified="2019-11-13" version="1">MAKAFKKSALEEKAGIESSKLSNAAAIAKIQQKRKTQPTTEALVTQILEGNITALSRAITLVESSNPSHLNQANAIIKACLPHANASVRIGITGVPGVGKSTFIEAFGIHLTSEGKKVAVLAVDPSSTLSRGSILGDKTRMDDLVKNENAFIRPSPSGTSLGGVARKTRESIILCEAAGFDTIVIETVGVGQSETAVHSMVDFFLLLKLSGAGDELQGIKRGIIEMADAIAINKADGENLKAAKLAKVEFNRALHLYPEKDSQWQPKVILCSALQREGIADIWEMISSYLEHTKKTGFFERHRKLQNKFWLLQTIEDRLKSDFFNRQKIKTELKVQLQLIEDGKTTPFVAADYLLGLND</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH29</accession>
    <name>A0A5C6ZH29_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">TlpA family protein disulfide reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_08670</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013740">
        <property type="entry name" value="Redoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08534">
        <property type="entry name" value="Redoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022789098" evidence="4">
        <location>
            <begin position="18"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="5">
        <location>
            <begin position="301"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD89445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="436" mass="48994" checksum="61CF95C7C9CAAADB" modified="2019-11-13" version="1">MKSILSILLLLPFLNFAQHSVSGTFLPAENYTYALLYQSKPSGTEYLDRSKIGEAGDFKIEMDSSYTPGMYKIVYALPAEEYNFSFIYDGKENIAITLSEDQGLAFTESSENKLWSSYTNSINLVNRSINNFYTQQSSDQKALTAIFKTLGNTQDSFEQAANGMLVSVFIKANRPYAPKEYQNLSSYSQNVKRSYLDAVDFGDPLLQSSDFLMDRVITYIFGSSEANSTAQFKTDVATLVAKIGTNNPIIKTILLETIWRKFKLMDSVEMANYVSDTYLMALAKNANYTALIEELKVDKSTALGSMAPNFDIEYLKDGKAVKTNLYDLAGAENYLLIFWSSTCGHCQEELPKIKELLSNKPNVNVIAIGLEDDDVIWKNAIKQFPEFIQVLGLGRWDNPISNDYGIASTPTYFLLNHKKEIIAKPYDVEALKAELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHA9</accession>
    <name>A0A5C6ZHA9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SDR family oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12585</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="228" mass="24631" checksum="BBBF49EEFABC1476" modified="2019-11-13" version="1">MKTKNIIITGTSRGIGFELAQLLAAQGHKVLALSRNANPVTNLKLENISAFAFDLNAEGDYKKVEQFIKNEWKHVDVLINNAGAIVNKPFAETSMDDFKKVYQTNVFGAAELTRIVIPFMKADGHVLSISSMGGIQGSMKFPGLAAYSSSKAAIITLTELLAEEYKEAGPQFNVLALGAVQTEMLAEAFPGYEVHTSAKGMATYIADFALTGNQFYNGKVLQVSNSTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI22</accession>
    <name>A0A5C6ZI22_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HIT family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_08565</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001310">
        <property type="entry name" value="Histidine_triad_HIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46648">
        <property type="entry name" value="PTHR46648"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01230">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00332">
        <property type="entry name" value="HISTRIAD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="SSF54197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIT" evidence="2">
        <location>
            <begin position="4"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Histidine triad motif" evidence="1">
        <location>
            <begin position="91"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="129" mass="14448" checksum="53500541F666090B" modified="2019-11-13" version="1">MASLFTKIINGEVPSYKIAETEDYLAFLDINPNAKGHTLCIPKKEVDKIFDLDEKTYHGLMEFSRQIAVALEVAVPCKRVGMSVIGLEVPHVHVHLIPLNSMDDAQFTTKVTLDKEEFEATAKRIASFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI44</accession>
    <name>A0A5C6ZI44_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">AhpC/TSA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_11490</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025380">
        <property type="entry name" value="DUF4369"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14289">
        <property type="entry name" value="DUF4369"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="241"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="385" mass="43002" checksum="1669ACE347553C14" modified="2019-11-13" version="1">MMKKLFFFLSLGAMVCSCNTELKTPIEGYRVVGETPGVYNGIRVYLHVLDQKGRQRSIDTAIVLNERFTFEGSLKGPQYVELTVNSIKGTLPLILIPEEVRLTIDSNDVGNSNISSSNANDALKTYNQTISAIDDEYNTLAQQLNKQSTSNDADPDVVSQKLAQIKARKDAYPYEFIKANTDNYYSLILINEMLWKRKMEVNKLEQSYAALGKDITASDFGQEVNRRIAATKAAIAPLMATEIGQQAPNFTAPTPEGTSFKLYDNLGKVTIVDFWAAWCGPCRRENPNVVKVYDKYHDKGLEIVGVSLDGNRRQQDPKAAWIKAIKDDKLTWHQVSNLNYFNDPVAKAYAIQSIPATFILDANGKIIAKNLRGASLERKIAELLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI79</accession>
    <name>A0A5C6ZI79_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Histidinol-phosphate aminotransferase</fullName>
            <ecNumber evidence="3">2.6.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Imidazole acetol-phosphate transaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">hisC</name>
        <name evidence="5" type="ORF">ESY86_10450</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>2-oxoglutarate + L-histidinol phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:23744"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57766"/>
            <dbReference type="ChEBI" id="CHEBI:57980"/>
            <dbReference type="EC" id="2.6.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 7/9.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.9" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00012"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004400">
        <property type="term" value="F:histidinol-phosphate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01023">
        <property type="entry name" value="HisC_aminotrans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005861">
        <property type="entry name" value="HisP_aminotrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01141">
        <property type="entry name" value="hisC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00599">
        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 3 5" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="4">
        <location>
            <begin position="47"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="3">
        <location>
            <position position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD88910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="351" mass="39402" checksum="689E8C0077A2E7D8" modified="2019-11-13" version="1">MTKNFNIQNLLRDNIKSLKSYSSARDEFQAASSDLVFLDANENPFENGVNRYPDPQQIKLKQRLSQLKGIPSNQILLGNGSDEVLDLIFRAFCEPNRDNVLTLPPTYGMYSVLANLNAIEVIEIALDTHFEPKVEAILKASNSHSKLLFLCSPNNPTANSFKSASIEKLIKNFNGLVVIDEAYIDFSKVESWVSRLAVFPNLIVTQTLSKAYGLAGIRLGICYASAEIIAILNRIKPPYNINELTQQKALERLNDPAQVSEEIQKLVQQREWLISELKQIAFVGTVYPSDANFILAKVDDANKRYSELIKQGIVVRNRTNQVGCENCLRFTVGTQMENIKLIKALQDLTGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIB1</accession>
    <name>A0A5C6ZIB1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_12895</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="433" mass="50388" checksum="5402D0A1F6976F84" modified="2019-11-13" version="1">MSKRGIELSNNFYLGLHKELLQLFYKHNSIEIKSLTVFQLYGFGNYDEGSANLKSFITEKTGKWINGKYLYNKKREIDASHKTKIKIRRDYLTILVTAAGYQGYNDYLQNSTYISADVREVEQAILQGSVKNEHVLYYVGYYVEDRRYYIKSKFTIYQLKSASWEILYWERDEEPTTYSYFGKCVPTGDSALSFYFSKEDSSLNKECFVNLFYGNNMNNKPVLLGAYCGFDRSNNPVIGKLIFEEVANAEAQNEKVRSHEINPIFHHHLYSQRLEVDGVLPHKDSDLAVSINRLEIINFLIGSYRGYYLDSNDYLIPISFQVINELGEIKLKINKTNFEGIGRLSITENYLISEFNKKNQPSYSQFSLQVQPLEKDLFVSHMLIYTGGNVINGKGLLWKMDEKKSKEIPLTNEFYINKSDIEPEKVEKINQYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZID0</accession>
    <name>A0A5C6ZID0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4369 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_13005</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025380">
        <property type="entry name" value="DUF4369"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14289">
        <property type="entry name" value="DUF4369"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4369" evidence="1">
        <location>
            <begin position="24"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="231" mass="26302" checksum="DEFC32D24513DECA" modified="2019-11-13" version="1">MKRFAAILITLVLFSCGNEQPKDFTLKGSIEDLKKGTVFLKRQQDSVLVTLDSLEINGNSSFELHATLEEPEILFLTLDKNDDEDGTVVFFADKGVTEINSTLKNFNYNAKVKGSKQQALLDEYLLMMSKFNDKNLDMLKERLESQMAQDSAKTNQLQKDFDGLLKRKYLYTINFAINHKDSELAPYLAISEIPNTSVKFLKQIYDALDDNIKNSKYGVMLKESIDEKTQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIG7</accession>
    <name>A0A5C6ZIG7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="11">TrkH family potassium uptake protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">ESY86_10040</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015379">
        <property type="term" value="F:potassium:chloride symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003445">
        <property type="entry name" value="Cat_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004772">
        <property type="entry name" value="TrkH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02386">
        <property type="entry name" value="TrkH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006247">
        <property type="entry name" value="TrkH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0630">Potassium</keyword>
    <keyword evidence="4" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="71"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="137"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="185"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="238"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="276"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="343"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="404"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="469"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="329"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="330"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="446"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="447"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR006247-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD89101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="497" mass="55287" checksum="92F543B0373C9221" modified="2019-11-13" version="1">MKLNFRIIFHFFGLLLLFNGGFMLLSTVISLIYEDGVTSKLFQSGAIISALGGVLMYLTRDHRKELNKREGYIVVAFGWIVMSLSGTLPYIMTDAIPGFTDAFFETMSGYTTTGATILNDIEAVPKGVLFWRSMTHWIGGMGIIVLAIAILPLLGIGGMQLFAAEAPGPNADKLHPRITDTAKRLWFIYFGYTAAETILLQVAGMSFFDAINHSLCTLSTGGFSTKNASVAYWNGQPLIQYIIIFFMFLAGTNFVLSYFVFKGRIQKAIMDEEFKWYLTFIAMFTIVASLIIYFNADFSISSIEHPMVYGKAEASFRHAMFQIVSVVTTTGFITADYTLWTPFLLVLFFGIMFLGGSAGSTSGGVKVVRHMIMIKNGFLEFRRALHPNAILPVRYNERAISGDIVFNVLGFFILYMLSFIIGALVFSMFKIDFQSAVGLSASSLGNVGPALGNFGPVNNYAALPMLGKWWASFLMLIGRLELFTVLILFSPFFWKDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIM2</accession>
    <name>A0A5C6ZIM2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">EamA family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_08190</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="218"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="270"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="7"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="154"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="292" mass="31832" checksum="706E09514A382475" modified="2019-11-13" version="1">MKISNKKWIYLLLLSLIWGSSFILIKKSLLGLSPFQLGALRTIISGVVLLCFGYGRLKTIERKSWKWVVLSGFLGSFIPAFLFAIAETEIDSAITSILNSLVPLNTLLLGFAIFKIASTKRQILGVIIGFVGTSMLIFKGAELNPDQNYLYAGFVIISTIMYGLNANIIKNYLQEVKPLAIAAGSYVVIIIPAILILIGSDFFTSETFAAPNFKMAMLYVSLLSIFGTALAKVVFNSLIQMATPVFASSVTYLMPVVALAWGLLDGETFGFMQLLASAVILLGVFLANKRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIN4</accession>
    <name>A0A5C6ZIN4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PKD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_04570</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00041">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000859">
        <property type="entry name" value="CUB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022409">
        <property type="entry name" value="PKD/Chitinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000601">
        <property type="entry name" value="PKD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035986">
        <property type="entry name" value="PKD_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00431">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00089">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49299">
        <property type="entry name" value="SSF49299"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="SSF49854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50093">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023094503" evidence="1">
        <location>
            <begin position="20"/>
            <end position="1325"/>
        </location>
    </feature>
    <feature type="domain" description="PKD" evidence="2">
        <location>
            <begin position="178"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1325" mass="137811" checksum="4A1BC4D89E1E0D87" modified="2019-11-13" version="1" fragment="single">MKKQILLFLVLLSILCAHGQDISMQDGTFNQCQDRFFDSGGEFGNYTSNENFALTICPNNAGDVIELSFTTFNTQLVDVMTIYDGADNTAPSLGSYSGINSPLIVEASSPSGCLTIEFVSNATGVTIGWAADIACLTPCQDIVANLDSTNPGFDVNNIVVADVDEVITFNGSGAFSVNGSGATYLWDFGDGNTGSGATATHQYATAGVYDITLTITDTNPAGCSSTNAIDLTAQIGASGPGNPYVNAGDDVVIDCADDCAEISAEFLEIGETNTYTVSQIPFVPPFPFQGLSNPLNPNIDDAWSSVDNLPFDFCFFNNIRTQFQVGSNGVISFDVDPSDNSNEYGFTQTLPNNSNTTLSEANIFTPCHDINPAVGSSEEIGWEIIGTAPNRVLAVSFYNVPLYSCTNLVATHMAVFYETTNVIDIYIKDKPFCASWNNGNAVVGIQNDAGTIAFVPPNRNTGQWSTTDEAWRFTPSGQSITDFAWLDESGTVIATTPTFEVCPATQATYTAQVTYINCNGDEVIVTDDVVVSKDTPFDVELGPDQQLCEGDPDVILDADIASPTAQYIWFLDGIFITGEESPTLTVASPNSGVYSVQVTDQSCALLSEVEVSFNGVPDTAFSLSPNCNGALATILGNTGGTFTFNPAATDGANIDAITGEITNTTSGASYTVEYSIAGLCPSSSTQNVTITDLDNTSFTLTATCDGAIATIDGNSGGVFTFNPLPADGAMIDAATGTITGGTFGTVYTVQYATSGVCASSSTETVSIVPADDPAFSLQPNCDGATATISGDTGGTFTFNPVPTDAATIDASTGTVSNAVPDATYTVEYTTAGPCVQTAQQSITVFSAEDASFTYTPSCDNAIATITGDLGGSFAFDSNSPSDGAVLDAVTGEITNPVSGETYAVNYSSSGNCPETTTVSVTILPQDDSSFTIAPTCDGATTTITGLVGGTFSLNPVPTDGTIINTSSGTVTGGAYATEYTISYTTNGACPTTTTQSFTVFSQPIIFDPTPLEVCDDGVPDGLTSIDLSMKNSEVTGNNPGYTVSYHKDQADADSDTDALPVPYTNEANGQVVFVRVEDNTTSCHATTSLVLTVQQAPVANDPAPLEYCDPDSDGFGVFDLTLRDAEITGGVAGLEVSYHETFADAQNGVNAVGSPYSNIVAGTQVLHARVESATVATGCATLVELVLIVNPTPAVPAEISDYVLCDSDADGVSQFDLGTKEAEITGSQPTLAADLDLILTYHLSAADALSGNDAISNVGNYTNTGNPQTIFVRLEGESNGCADTGSFEIRVDLPPVAVLPAPLQLCDDGVADGVTVFDLSVRDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIS1</accession>
    <name>A0A5C6ZIS1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TlpA family protein disulfide reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="37"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="179" mass="20470" checksum="B6142658E1D6D6CE" modified="2019-11-13" version="1">MTRKKILLFITLFVVLGTLSYLSYSVIVKAKEKKLTANRLQIIPEFQFEDLKSSTFTNASLQENKAAIFVYFNTQCDYCQHEAQSISERLDELTNVQFIFVSTEDIETIKQFSENHNLNHQPNITFVHDNTDIFSTKFGATAMPYLLIYDKDQQLIKKHKGQLNANGILKALIPAKAGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIS7</accession>
    <name>A0A5C6ZIS7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PaaI family thioesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06135</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003736">
        <property type="entry name" value="PAAI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00369">
        <property type="entry name" value="unchar_dom_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4HBT" evidence="1">
        <location>
            <begin position="51"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="141" mass="15427" checksum="0F444F05A1A94C3C" modified="2019-11-13" version="1">MQRTKEDVLAEANAASKNTLMETLDIEIVDYGPDFLVARMPVTPKVHQPDGVLHGGATAALAESVGSFASHIFLDIDNKFVRGLEISANHLKSVSEGHVYAKATFLHKGRTTQLLDIRITDDNDTLISVCRLSTISLPKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ01</accession>
    <name>A0A5C6ZJ01_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">UDP-N-acetylglucosamine 1-carboxyvinyltransferase</fullName>
            <ecNumber evidence="7">2.5.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Enoylpyruvate transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">UDP-N-acetylglucosamine enolpyruvyl transferase</fullName>
            <shortName evidence="7">EPT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">murA</name>
        <name evidence="9" type="ORF">ESY86_06685</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>phosphoenolpyruvate + UDP-N-acetyl-alpha-D-glucosamine = phosphate + UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine</text>
            <dbReference type="Rhea" id="RHEA:18681"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:68483"/>
            <dbReference type="EC" id="2.5.1.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the EPSP synthase family. MurA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.7" evidence="7"/>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008760">
        <property type="term" value="F:UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019277">
        <property type="term" value="P:UDP-N-acetylgalactosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01555">
        <property type="entry name" value="UdpNAET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.65.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00111">
        <property type="entry name" value="MurA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001986">
        <property type="entry name" value="Enolpyruvate_Tfrase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036968">
        <property type="entry name" value="Enolpyruvate_Tfrase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013792">
        <property type="entry name" value="RNA3'P_cycl/enolpyr_Trfase_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005750">
        <property type="entry name" value="UDP_GlcNAc_COvinyl_MurA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00275">
        <property type="entry name" value="EPSP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55205">
        <property type="entry name" value="SSF55205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01072">
        <property type="entry name" value="murA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1 7" id="KW-0132">Cell division</keyword>
    <keyword evidence="3 7" id="KW-0133">Cell shape</keyword>
    <keyword evidence="6 7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="EPSP_synthase" evidence="8">
        <location>
            <begin position="7"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoenolpyruvate binding" evidence="7">
        <location>
            <begin position="22"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="121"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="320"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="342"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD89883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="438" mass="48011" checksum="2A8FA54F1D0D9357" modified="2019-11-13" version="1">MSTFIIEGGHQLKGKIQPQGAKNEALQILCAVLLTDQEIKIDNIPDIIDVNKLIALLKKLGVKINKIGQGSYTFKADDLNLKYLESAEFKEDGKGLRGSIMIVGPLLARFGKGYIPKPGGDKIGRRRLDTHFEGFIKLGAKFRYNKEDYFYGVEADKLKGTFMLLDEASVTGTANILMAAVLAEGTTTLYNAACEPYLQQLCKMLNRMGAKISGVGSNMLIIEGVDTLGGTSHRMLPDMIEIGSWIGLAAMTQSELTITNVSWDDLGQIPDVFRKIGITVERRGDDIYIPAHTNGYEVQSYIDGSILTFSDAPWPGFTPDLLSIVLVVLTQARGSALVHQKMFESRLFFVDKLIDMGAKIILCDPHRATVIGHDFKSKLKATTMTSPDIRAGVALLIAALSAKGTSTIHNIEQIDRGYENIDERLRAIGAKITRVEGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ32</accession>
    <name>A0A5C6ZJ32_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Excinuclease ABC subunit UvrA</fullName>
            <ecNumber evidence="15">3.1.25.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">uvrA</name>
        <name evidence="15" type="ORF">ESY86_06100</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.25.-" evidence="15"/>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009380">
        <property type="term" value="C:excinuclease repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004602">
        <property type="entry name" value="UvrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041552">
        <property type="entry name" value="UvrA_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041102">
        <property type="entry name" value="UvrA_inter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17755">
        <property type="entry name" value="UvrA_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17760">
        <property type="entry name" value="UvrA_inter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00630">
        <property type="entry name" value="uvra"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0228">DNA excision</keyword>
    <keyword evidence="12" id="KW-0234">DNA repair</keyword>
    <keyword evidence="11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ABC transporter" evidence="14">
        <location>
            <begin position="584"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="624"/>
            <end position="631"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TXD89776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="927" mass="103901" checksum="F002AA9923342B12" modified="2019-11-13" version="1">MNNTLLDVNPKQNIIIKGAKLHNLKNIDVVIPRNKLVVITGLSGSGKSSLAFDTLYAEGQRRYVESLSSYARQFLGRLNKPKVDYIKGIAPAIAIEQKVNSTNPRSTVGTTTEIYDYLKLLFARIGKTYSPISGDPVKKHRTKDVLDHVKSFEEREKLLLLAPIVLEEGRSMEDKLKALKQQGYARIQYKEEVLRIDDAIEKNIESEVFLVVDRIIVKHEDDFFNRLADAIETAFFEGKGTSIIESLGTKKRREFNNKFELDGMQFLEPNPHLFSFNNPYGACPKCEGYGDVIGIDDELVIPNTALSVYENAIFPWRGESMSWYRDQLVNNSHKFDFPIHKPFFQLTDAQKQLIWDGNKYFEGLHAFFAELESKAYKIQNRVMLSRYRGKTKCSLCKGKRLRQEANYVKITNVTITDLVEMPLDKLSQFFKELELNEYDLQIAERLLQEINNRLAFLSNVGLDYLTLNRKSNTLSGGESQRINLATSLGSSLVGSMYILDEPSIGLHPKDTEKLIDVLKALRDLGNTVIVVEHDEDIMQAADEIIDIGPEAGTLGGEVVAVGTFEDILKSSSLTAQYLNGTMEIELPKKRRTSKYQIEVLGARANNLKNIDVVFPLNMLTVITGVSGSGKSTLVKKILFPAIQKELTGFGDKAGQFSELKGNYKNIKHIEFVDQNPIGRSSRSNPVTYIKAYDDIRALFADQKLSHIRHFKAKHFSFNVDGGRCETCKGEGEVTIEMQFMADVHLTCETCNGKRFKKEVLEVAFEGKNIDDVLSMTIDDAISFFAAQGQTKIQGKLQPLQDVGLGYVTLGQSSSTLSGGEAQRIKLASFLGKGTKSDKALFIFDEPTTGLHFHDIKKLLKSFQALIEKGHSIIVIEHNLELIKCADYVIDLGPEGGSRGGELVAHGTPEEIIKNKKSITGRYLKAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ75</accession>
    <name>A0A5C6ZJ75_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Two component regulator three Y domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_05635</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Single-pass type I membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RLP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045273">
        <property type="entry name" value="RLP23-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR27004">
        <property type="entry name" value="PTHR27004"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="291" mass="32339" checksum="CD3483461FCBB52C" modified="2019-11-13" version="1">MASLFTFANVSPKEKAALVAFYKSTHGESWTNTWQLDKPVEEWFGVVVENDKVTQLNLSFNKIKGELPENFGDLIHLTQINFFRNQISGKLPNSISNFKALVTLNMAFNEISGALPDSIGGLESLVTLQLFMNRIEGKIPVSIGQLKNLEHLELYNNNITGELPTSLKNLTKLKSILVSSNKFSGKLPSEISYLKNLKVLSLFDNNFFGTLPNSICDLTGLEELVLSNNAFYGNLPTNIAALSKLKVLMLGNNAFKGELVKLEAKFPNMQQFDIINSDNQGTIVTLDEEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJF7</accession>
    <name>A0A5C6ZJF7_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">dTTP/UTP pyrophosphatase</fullName>
            <shortName evidence="2">dTTPase/UTPase</shortName>
            <ecNumber evidence="2">3.6.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Nucleoside triphosphate pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Nucleotide pyrophosphatase</fullName>
            <shortName evidence="2">Nucleotide PPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">maf</name>
        <name evidence="3" type="ORF">ESY86_03470</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H2O + UTP = diphosphate + H(+) + UMP</text>
            <dbReference type="Rhea" id="RHEA:29395"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="EC" id="3.6.1.9"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>dTTP + H2O = diphosphate + dTMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28534"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37568"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="EC" id="3.6.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Maf family. YhdE subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.9" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036218">
        <property type="term" value="F:dTTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035529">
        <property type="term" value="F:NADH pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036221">
        <property type="term" value="F:UTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00555">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00528">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003697">
        <property type="entry name" value="Maf-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43213">
        <property type="entry name" value="PTHR43213"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02545">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006305">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
        <property type="entry name" value="SSF52972"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00172">
        <property type="entry name" value="maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="2">
        <location>
            <position position="19"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="2">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="2">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="195" mass="22208" checksum="19C5D1565C6AF67F" modified="2019-11-13" version="1">MLQEHLKHHNLILASGSPRRQQFFKELGLDFEIKLKPVVEEYPEQLVHFEISDYLAELKALPFKETLKTNDILITSDTIVWHENQALGKPKDAEEAFDMLHAMGGKTHEVITSICFTTKTTQKTVNAVTKVSFKDLSKAEIHYYINNFRPYDKAGAYGIQEWIGQIGIVAIEGSYTNVVGLPTHLLYKTLLEFAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK75</accession>
    <name>A0A5C6ZK75_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ATP synthase subunit delta</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">ATP synthase F(1) sector subunit delta</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">F-type ATPase subunit delta</fullName>
            <shortName evidence="6">F-ATPase subunit delta</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 7" type="primary">atpH</name>
        <name evidence="7" type="ORF">ESY86_07750</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.</text>
    </comment>
    <comment type="function">
        <text evidence="6">This protein is part of the stalk that links CF(0) to CF(1). It either transmits conformational changes from CF(0) to CF(1) or is implicated in proton conduction.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ATPase delta chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01416">
        <property type="entry name" value="ATP_synth_delta_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026015">
        <property type="entry name" value="ATP_synth_OSCP/delta_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000711">
        <property type="entry name" value="ATPase_OSCP/dsu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11910">
        <property type="entry name" value="PTHR11910"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00213">
        <property type="entry name" value="OSCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00125">
        <property type="entry name" value="ATPASEDELTA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47928">
        <property type="entry name" value="SSF47928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01145">
        <property type="entry name" value="ATP_synt_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0139">CF(1)</keyword>
    <keyword evidence="2 6" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="3 6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD89731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="178" mass="19545" checksum="555B638D5B89EE2C" modified="2019-11-13" version="1">MAGERAAIRYAKALLSLSEEKNASEDINKDMALMAETISKSKDLRFVLESPVLQSSKKQGAILAIFKDANALTVNLVDILNTNKRIPILGEVASQYMRLYDELKGIQVATVTTAVALDDVMRAKVLAKVKELTGKQAEVTNKIDESILGGFILRVGDTQYDASVANKLNKLKREFTLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK83</accession>
    <name>A0A5C6ZK83_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="4">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_01855</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="4"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="SSF47005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3 4" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="6">
        <location>
            <begin position="10"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="7">
        <location>
            <begin position="145"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="92"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="92"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="118"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD90731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="450" mass="49415" checksum="3BCBDA3F38C7E589" modified="2019-11-13" version="1">MSKEKGIPNTQELKMPKMGESITEGTIINWLVNEGDTFEEGDIILEVATDKVDNEVPAPVSGTLKEIVHKAKDVVPVGEVLAILEVSDEGKSKSKSESFSNKEKESHQEKEKIDTPKSSSKSSSSSTSTSSSTSTSTSISNSNTFFSPLIQSIAKEQHISFEELARIPATGHDGRLRKSDVFNYIEDGRPNKFAQLAAPQDPTAYRIPQLTFDKGKGKIIKMDRMRQMIADHMVYSTHTSPHVTAYVEADLTNMVNWRNANKKAFQEKYGERLTFTPLFVEAVAKAIKDFPNINASVDGANIIVKEDINIGMATALPSGNLIVPVVKNADQKDLKTLAENVNEMAGKARENKLTGDDVKGSTFTISNVGTFGSVMGTPIINQPEVAILALGIIKKRPEVIETEKGDEIAIRSMMYLSLSFDHRVVDGFLGGSFVRKVADYFEQFDADRTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK97</accession>
    <name>A0A5C6ZK97_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">16S rRNA (Guanine(966)-N(2))-methyltransferase RsmD</fullName>
            <ecNumber evidence="3">2.1.1.171</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rsmD</name>
        <name evidence="3" type="ORF">ESY86_03350</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.171" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052913">
        <property type="term" value="F:16S rRNA (guanine(966)-N(2))-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004398">
        <property type="entry name" value="RNA_MeTrfase_RsmD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004553">
        <property type="entry name" value="CHP00095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00095">
        <property type="entry name" value="TIGR00095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="193" mass="22033" checksum="BD5A7C0F3EE64C70" modified="2019-11-13" version="1">MRIISGEFKGRRITAPKKLPVRPTTDMAKESLFNILNNRYYIDEISVLDLFAGTGNLSYEFASRGCEQITAVDQDYGCIKFINETAESFGMTINTIKSDVFKFLEHAQGSHTVIFADPPYELPKEEFAKIAQLIFENSLLKEEGILVIEHSKRTDLSDLQHYVKSKSYGGNSFSFFEIATEEEEEEEEEEETD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKD2</accession>
    <name>A0A5C6ZKD2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Class I SAM-dependent rRNA methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_06200</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041532">
        <property type="entry name" value="RlmI_PUA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019614">
        <property type="entry name" value="SAM-dep_methyl-trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10672">
        <property type="entry name" value="Methyltrans_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17785">
        <property type="entry name" value="PUA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PUA_3" evidence="5">
        <location>
            <begin position="21"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltrans_SAM" evidence="4">
        <location>
            <begin position="127"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD89794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="409" mass="45631" checksum="06B78F24E4FD2735" modified="2019-11-13" version="1">MNLKFPKAQSESANAKTLATKLTAKGENYVQQGHPWVFSDSIVKINDDAKTGDLAIIFGKRKNAMIGIGLYDADSPIRIKMIYNASKPIQINSDFFLQKINSAYQKREPLLKTNTTSYRLIFGENDGFPSLIADVYEQVLVLKLYSEIWLPYLETILESLIQVSNTETVVLRLSRSLQQSDSHHFKDGDVVYGNLKAEVVQFVEHGVNFSANVIKGHKTGYFLDHRENRRQVGELSKGKTVLDVFSYAGGFSVHALANGATDVTSVDISAQALEIALHNGSLNDYSGQHHILAGDAFKILEQLIKDHQTFDVVIIDPPSFAKQQSEIQLAKKKYAQLAALGAKLTAQNGLLVLASCSSRMSTKAFYDINEQTLKKADRPFKVEQKTQHDVDHPIGFEEGAYLKCGYYRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKF3</accession>
    <name>A0A5C6ZKF3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF3857 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_01780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024618">
        <property type="entry name" value="DUF3857"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12969">
        <property type="entry name" value="DUF3857"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3857" evidence="1">
        <location>
            <begin position="65"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="668" mass="76461" checksum="45DCD3076D9381D1" modified="2019-11-13" version="1">MKKITCIIIFLLGSMTYSQDYEFGEVSKAELEEQFNPNDSSASATYLYKYRRTYFTYMQDEGFSLKTEIHERIKIYNQEGFDFATKKFWLHEDGSSREKYESLKGYTYDLVDGKVEDTKLRKDGIFENEKSKYTKEVAFTLPDIKAGCVIEYKYDIISPFISSIDEFELQAEVPIKKLEMSFESPEYFSYKLNTKGYLPVSPKSGRKTGTINFANRTRTSGAVVSSRMSYSKKQYSITTSKYELDNVPALRDEPYVNNIDNYRASVKYELSWTKFPNDPISYYSTTWDDVVKTIYKSDNFGGELDKSNYFEKDLDALLANTSVPMEKAALIFNHVKANVKWNGYYGKYTDVGVRSAYKDHVGNVAEINLMLTAMLRYAGLKANPVLVSSRNNGVPLFPTREGYNYVISAIELENQVVLFDATSMYSTPNILPFRTLNWEGRIIREHGSSALVDLYPKLKAETKTFMNVSLEGDGTITGKIRTFKTNHDAVNYRMSLLDKNRDEFLESLENDYGGIEVSGFEATNDLELSKPLILAYSFSTDNQLEVIGDKLFLSPMLFFTQNENPFKLESREFPVDFGYPSGSAYKINILIPEGYQVESLPESVVLELPNDLGTFKYLIQSDANAIQIAVDYDLNTPIVASTYYPFLKEFFEVLVKKEKEKVVLTKTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKI3</accession>
    <name>A0A5C6ZKI3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TlpA family protein disulfide reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06535</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="44"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="196" mass="22474" checksum="DF51EB5DA7963C64" modified="2019-11-13" version="1">MAKPRKMKWSTILFVVVLLLLIIPQTRKPIQIFLQKGMAKVVKPSAIENSERASLSTFNWKLKNDQGETVNFKSAEGKVIIINFWATWCPPCIAEMPDFETLYQDYKDNDAIEFWFVSNEKQSVTANFLEEKGYSFKSYQPSTQPPSNFNVSSIPRTFVIDTAGKIVLDKSGVADWDSDKMRRILDGLIENKFTMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKK6</accession>
    <name>A0A5C6ZKK6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Histidine phosphatase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_03310</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="161" mass="18318" checksum="48503077CA4FE0E3" modified="2019-11-13" version="1">MKKIILVRHGKSSWEHDVTDKERPLKKRGITDAHLVSEAFLTKKVSLDAIYSSAANRAFSTCEIFVKVFNREVASVTVLDKLYDFEGQIVIDFMKSLDDRYNNVMIFGHNNAFTSICNIFGDVYIDNLPTSGLVAIDFDVNSWVDIKKGKTSLTIFPRDFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKL0</accession>
    <name>A0A5C6ZKL0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="171" mass="19362" checksum="C8D0C7A161988EA6" modified="2019-11-13" version="1">MALNNIEYLLEKYDNGETSIAEEQQLKAYFAQDEVAPQLESYRIMFQYFDQTKKEQFTKDVPLETKKSHIYKWISVAAVAVLMIGILIPNVFGGKTYTSIAELPAEEQEVYHQTKKALSLLSSNFNDGASSMNALGFMSAKLNKGAEQVIQVKEFSKATNKLLKKKQTPKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL10</accession>
    <name>A0A5C6ZL10_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_01790</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="160" mass="17747" checksum="A1EFA348CAE0511F" modified="2019-11-13" version="1">MNPIIEPPKPKSNANKRELLFTFQSIIVTGLLAFTAIAFFLYYDLTIVKGIKVIFAPFLSVVPLLFILSILRDLKTGFKEGNYNKAEIIKFCLITAGITAAFTGITYLLTKIDALEILLAAIMAILSIVFFLKSKIKDILGMSIITGIAEGVIIYMIFLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL30</accession>
    <name>A0A5C6ZL30_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_02055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022933063" evidence="1">
        <location>
            <begin position="20"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="426" mass="49357" checksum="E4B11F189B48B384" modified="2019-11-13" version="1">MLRHLCLVIFLLFAYATNAQVPTTEIDTVGVDQDSLSKTRFIKQLGNGYFPTQFLDIDLRYLVKFNQYEGFRTGLGGVTNDAFSAKYRINSYVVYGFRDHRFKYRIGGGFRVNAPTNTWINLSYTDDLQETGSSDFITDKRFFSFFEPRLLNINLFHKYITKAVSVEHSISYHLLSETELAISKIDPTYDYLYRLDGIDYKNWHVSTAKIALQWSPYSTYEVKANDAIVEKEDGYPKFTLQLTKSFKDVVKGDFNFFKTDFRAIHKFKYNEQSFTEATLTTNIAFGDAPLSHLYHAYPNNVNKPTIIKRFSVAGINSFETMFFNEFFSDRLATLQLKHYVKPFDIGKRFKPQLVLISRFALGNMNNIARHQNIDFNTLDRGFSEAGLEINKLLFGFGLSFAYRYGAYHLPTFEDNLALKFTFNISL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL56</accession>
    <name>A0A5C6ZL56_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Iron-sulfur cluster assembly accessory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.300.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000361">
        <property type="entry name" value="FeS_biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016092">
        <property type="entry name" value="FeS_cluster_insertion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017870">
        <property type="entry name" value="FeS_cluster_insertion_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035903">
        <property type="entry name" value="HesB-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01521">
        <property type="entry name" value="Fe-S_biosyn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89360">
        <property type="entry name" value="SSF89360"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00049">
        <property type="entry name" value="TIGR00049"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01152">
        <property type="entry name" value="HESB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-S_biosyn" evidence="1">
        <location>
            <begin position="2"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="109" mass="11901" checksum="A075036959767AF4" modified="2019-11-13" version="1">MIKVSETAKKKVVELMSEDGFNSTIDFVRVGVKSGGCSGLSYDLKFDHEKQEEDKVFEDNGVKIIVDKKSFLYLIGTTLEYSGGLNGAGFVFNNPNANRTCGCGESFSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL59</accession>
    <name>A0A5C6ZL59_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Pesticidal protein Cry28Aa</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ESY86_05105</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001750">
        <property type="entry name" value="ND/Mrp_mem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003945">
        <property type="entry name" value="NU5C-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42829">
        <property type="entry name" value="PTHR42829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00361">
        <property type="entry name" value="Proton_antipo_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="64"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="156"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="194"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="236"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="260"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="347"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="378"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="407"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="444"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_M" evidence="9">
        <location>
            <begin position="116"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD90127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="495" mass="54997" checksum="273BEE26EA941607" modified="2019-11-13" version="1">MTLENHLDSMHPQSTKSDPIDTRKPMVSRFVTLLLWLLFLGNLAFLTLNFFNMPEWSWKSLFRINGFTILIWTTVTFFSAIIGSYAGNYLSGFKFHSRFMMLCLGFTLSVMLLVMSNHVVLLIFSWLIMGIFMSQLIGIDKTWGEAREASKFTQKYFLIGTLFLTIGLLLLAFYSKTFTISGLSTVVSELPLYILIPSALCIISAAVVQSAMYPFHRWLLSAMTAPTPASALMHAGFVNGAGILLALFATLLFASNTLTILFIIGGLTAIIAQFTKLLQVNVKQKLACSTIAQMGFMIMQCGLGFFNAAVAHLILHGFYKAYLFLSSGEEIAQTTPEKHVQLKIKPLQALAVLLFGGLGAYLFAIWTGKGLEMDSGVFLTLIVAITVGQATYNMVKEQSLSLVQKILVPAVLFVAGIGIYALMYNGVSILMLDMPMVAQPIPLTWVQITFGIIFLLGFFIMKLGVYKKLPWLYVKLMNISQPYKNSVLMYKSKSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLE6</accession>
    <name>A0A5C6ZLE6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CDP-glycerol glycerophosphotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_04535</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UDP-N-acetylglucosamine 2-epimerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043148">
        <property type="entry name" value="TagF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016886">
        <property type="entry name" value="UCP028458_glyceroPtfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003331">
        <property type="entry name" value="UDP_GlcNAc_Epimerase_2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02350">
        <property type="entry name" value="Epimerase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028458">
        <property type="entry name" value="UCP028458_glyceroPtfrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Epimerase_2" evidence="2">
        <location>
            <begin position="176"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="359" mass="41705" checksum="249CA1BAEFCFDE4B" modified="2019-11-13" version="1">MNYKFLIYISYSYAIPIGKPLEQEILKRGYTVKWFSDLESGKKALANNEHLLATIEEAVAFEPHIVLAATDDIPDFISGLKVQIFHGFFAQKRPEENNRFAHFRIRGFFDLYCTQGPSTTSVFKKLAVSKGFFKVEQTGWSKMDPLFPLKEKARQNLPTVMIASTFTQRLSLAYHTAVFKEIERLSNSDTYQFIMVLHPKLPDEIIAKWKSLENQNFKFYDTTDLIPLFQKADFLFADTTSAIQEFLLQKKPVVTFRHTLEHDYLIQVEDTQHIEKAFEQALQPSEALLSKIEAFIAQLHPYEDGKSSTRVINATIDFLHADKTNLKNKPLNLIRKYKIRKRLDYFTLKSYSKAYTIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLH2</accession>
    <name>A0A5C6ZLH2_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">Adenylosuccinate lyase</fullName>
            <shortName evidence="11">ASL</shortName>
            <ecNumber evidence="4 11">4.3.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">Adenylosuccinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">purB</name>
        <name evidence="14" type="ORF">ESY86_03830</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes two reactions in de novo purine nucleotide biosynthesis. Catalyzes the breakdown of 5-aminoimidazole- (N-succinylocarboxamide) ribotide (SAICAR or 2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate) to 5-aminoimidazole-4-carboxamide ribotide (AICAR or 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide) and fumarate, and of adenylosuccinate (ADS or N(6)-(1,2-dicarboxyethyl)-AMP) to adenosine monophosphate (AMP) and fumarate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + fumarate</text>
            <dbReference type="Rhea" id="RHEA:23920"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:58443"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="EC" id="4.3.2.2"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:23921"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>N(6)-(1,2-dicarboxyethyl)-AMP = AMP + fumarate</text>
            <dbReference type="Rhea" id="RHEA:16853"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:57567"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="4.3.2.2"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:16854"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 2/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 11">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.2" evidence="4 11"/>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00132"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00075">
        <property type="reaction ID" value="UER00336"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070626">
        <property type="term" value="F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004018">
        <property type="term" value="F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044208">
        <property type="term" value="P:'de novo' AMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004769">
        <property type="entry name" value="Pur_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013539">
        <property type="entry name" value="PurB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08328">
        <property type="entry name" value="ASL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00928">
        <property type="entry name" value="purB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 11" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lyase_1" evidence="12">
        <location>
            <begin position="14"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="ASL_C" evidence="13">
        <location>
            <begin position="330"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TXD90505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="447" mass="50410" checksum="7CE7F53360017CE9" modified="2019-11-13" version="1">MSISSLSAISPIDGRYRNKVSNLAPYFSEEALIKYRVRVEIEYFIALCEFGLPQLKDVDSSTFEDLRAIYTNFSSEDAQAIKDIESITNHDVKAVEYFIKKQFDQLKLSRFKEFIHFGLTSQDINNTAIPLSIKEAMNDVYVPEYLEVFKTLKSLANDWKDIPMLARTHGQPASPTRLGKEIEVFAARLEAQFDLLNDIPSAAKFGGATGNYNAHKVAYPDKDWKAFGTKFVQETLGLHHSFPTTQIEHYDHLAALFDGLKRINTIVIDLDRDIWTYVSMEYFKQKIKEGEVGSSAMPHKVNPIDFENSEGNLGFANAIFEHLSAKLPISRLQRDLTDSTVLRNVGVPFAHTLIGFKSTVKGLHKLLLNKAKFAQDLEQNWAVVAEAIQTILRREGYPNPYEALKGLTRTNEVINAKSIAAFIDTLDVSEAIKTELKVITPSNYTGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLK4</accession>
    <name>A0A5C6ZLK4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Penicillin acylase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_04035</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="5">Binds 1 Ca(2+) ion per dimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S45 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017000">
        <property type="term" value="P:antibiotic biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.439.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014395">
        <property type="entry name" value="Pen/GL7ACA/AHL_acylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043147">
        <property type="entry name" value="Penicillin_amidase_A-knob"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023343">
        <property type="entry name" value="Penicillin_amidase_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043146">
        <property type="entry name" value="Penicillin_amidase_N_B-knob"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002692">
        <property type="entry name" value="S45"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34218">
        <property type="entry name" value="PTHR34218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01804">
        <property type="entry name" value="Penicil_amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001227">
        <property type="entry name" value="Pen_acylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0865">Zymogen</keyword>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="274"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="346"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="349"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001227-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001227-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD90545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="804" mass="91890" checksum="50DE829740221C88" modified="2019-11-13" version="1">MRFFKLGIALILTVLVFFVLNTKLGSIPPMGKFLNPVSGVWQNDSEEIITGNLSIDGLLDVVTVHYDSILIPHIFAQNDSDLYRAQGYITAKHRLWQMEFQTFAAAGRLSEIIGEKALEYDQQQRRRGMIFGAENALIKMKEDPETYKFMEAYRDGVNSYINQLDTNDLPVEYKLLDYKPELWSSEKTALLLMYMTKMLAGGDSDLEYTNALHLFGKERFDLLFPDFYGELDPVIPEDTNWDFITTEITATPEHKIPRDSISETIDKPHPNNGSNNWAVAAEKSASGNAILANDPHLGLNLPSIWFVMQLQTPEHNAMGATLPGALGVISGFNNHISWGVTNATRDVLDWYKIEFKDASRQQYKYGNGWKNTRVRVENIKINGAETLQDSVIYTHYGPVTYDKNFKGNGEKIGYAMKWTGHIGGNNQLPFLQLNKAKTYEDYENALKNYTAPAQNFAFASTSGDVALWIQGLFPNKWKGQGKFLMDGSNPENEWQSFIPQQFNAHVKNPERGFISSANQHPVDETYPFYVFNDGYETYRNRVINDFFRNKEKISVEDFKSLQNNNFNLKASELLPNIFEHMDVTGLTSEEKEIYNQIKAWDFYSEIDQLAPSIWDLWWEKLYDQVWDEFENDDLALDTPFIYQTIYLLKNNPEDQFMDIVSTPETETAKDLFLITFKASAKELLDWKAKNGNYNWSEYKGTFTGHLLQALPAFSRFDIPIGGDYNTVNAASKNHGPSWRMIVEMSTPPRALGIYPGGQSGNPGSKYYDNFIDDWAAGNYHELLFMQDNTTNSQIMATQTLTPKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLW2</accession>
    <name>A0A5C6ZLW2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_02640</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="65" mass="7488" checksum="8746557FC6066CAA" modified="2019-11-13" version="1">MFTYRWERSFELFVKKILRNYKAMKDDDQMVDAGKAIDNAVNETKEAGKAVGEAVDSLDKQDDNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLW3</accession>
    <name>A0A5C6ZLW3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023117533" evidence="1">
        <location>
            <begin position="27"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="173" mass="19744" checksum="73E6F6E2B4B1EC03" modified="2019-11-13" version="1">MKLITRTFYVTVFAIGLLGLCQTSHAQSSMSLQAQSAIKFDSVYFQEWFAGIKVGGTGFNIFFPNVDKDDRIELQDVYFRNLKGKLSKVKDKYVATLKNPSKHYTFKKADKPEGYPFDLKDSECVISYNENGQTKFMKVKVLDERAGTYYENGPPSIYQYDATTRMATVDETD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM53</accession>
    <name>A0A5C6ZM53_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_03625</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="150" mass="16725" checksum="C40AAB18D1415C54" modified="2019-11-13" version="1">MKTRILLFLLGIGLLNSCVNDDNADYQSTEINFTEIGKGALFGNGQEGISQSNLTISNTNEWQNLISQMNSVNNVSENFTETDINFNEFTVFAIFLEVKGHGWEIGTENVIENENNISVTTLENEAINSVMTQPFSIIKIPKTEKTIIVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMB1</accession>
    <name>A0A5C6ZMB1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="66" mass="7507" checksum="8A092D2FD2A964CD" modified="2019-11-13" version="1">MTKIKVSIKRVIITALIGGAIFTAVVSGFDYVFGKPFSWPRLGLYFGFATLMYGFLTWRNLRKGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMC1</accession>
    <name>A0A5C6ZMC1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4159 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025297">
        <property type="entry name" value="DUF4159"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13709">
        <property type="entry name" value="DUF4159"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4159" evidence="1">
        <location>
            <begin position="31"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="223" mass="25137" checksum="42EDEA46317EB7A0" modified="2019-11-13" version="1">MASNSKYLNNLSILLLLILSLTGISVGAQDLAVLKYKGGGDWYSNPTSLPNLIAFCNANINTKMKLKPEVVEPGSIDIFQYPLLHMTGHGNVFFSDEEAENLRKYLFSGGFLHIDDNYGMEPYLKKELLKIFPNQDLVELPKTHEIFNAAFAFPNGLPKIHEHDGKRPQAFGIFHEGRLVLLFTYESDLGNGWEDPEVHNDPEEVRLKALKMGANIVKYAFEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMG6</accession>
    <name>A0A5C6ZMG6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Phosphoribosylformylglycinamidine synthase</fullName>
            <ecNumber evidence="11">6.3.5.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">purL</name>
        <name evidence="11" type="synonym">purI</name>
        <name evidence="11" type="ORF">ESY86_03810</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.3" evidence="11"/>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004642">
        <property type="term" value="F:phosphoribosylformylglycinamidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006164">
        <property type="term" value="P:purine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.650.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040707">
        <property type="entry name" value="FGAR-AT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041609">
        <property type="entry name" value="PurL_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010918">
        <property type="entry name" value="PurM-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036676">
        <property type="entry name" value="PurM-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036921">
        <property type="entry name" value="PurM-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036604">
        <property type="entry name" value="PurS-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02769">
        <property type="entry name" value="AIRS_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18072">
        <property type="entry name" value="FGAR-AT_linker"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18076">
        <property type="entry name" value="FGAR-AT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55326">
        <property type="entry name" value="SSF55326"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56042">
        <property type="entry name" value="SSF56042"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82697">
        <property type="entry name" value="SSF82697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FGAR-AT_N" evidence="10">
        <location>
            <begin position="14"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="FGAR-AT_linker" evidence="9">
        <location>
            <begin position="121"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="AIRS_C" evidence="8">
        <location>
            <begin position="395"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="domain" description="AIRS_C" evidence="8">
        <location>
            <begin position="795"/>
            <end position="916"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="990"/>
            <end position="1040"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="992"/>
            <end position="1040"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF18072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF18076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD90501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1290" mass="141466" checksum="B23FBB45C5468682" modified="2019-11-13" version="1">MIHFFGNQNSKLYAVQAKELSQEAISKLVWLFANQPKLEQASIDAFFVGPRAAMITPWSTNAVEITQNMGIEGIVRIEEFQSVTADFADFDPMISEKYKGLNQQSFIIDIQPEAIVSVEDISAYNKTEGLSLSDEEVEYLESVSKKIGRALTDSEVFGFSQVNSEHCRHKIFNGTFIIDGEEKPNSLFKLIKETAKQNPNTIVSAYKDNVAFINGPTVEQFAPKRADVPDFYTTEDFESVISLKAETHNFPTTVEPFNGAATGAGGEIRDRLAGGKGSLPLAGTAVYMTSYSRLEPTVDSAQDKPWEKSFPARQWLYQKPLDILIKASNGASDFGNKFGQPLICGSILTFEHDESQDASTETNTNTRKLAYDKVIMQAGGIGYGKLDQAIKEKPEAGDQIVVLGGENYRIGMGGAAVSSADTGALASGIELNAVQRSNPEMQKRAANVIRGMVESDNNTIISIHDHGAGGHLNCLSELIEDTGGCIDLDQLPVGDPTLSDKEIIGNESQERMGLLIAKKNLDHISKIAARERSPLYTVGEVTNDKHFCFTSKTKGNTPMALDLEDMFGSSPKTVMTDKTIKRSYDDVTYNRENFHEYLEQLLQLEAVACKDWLTNKVDRCVGGRVAKQQCVGPLQLPLNNMGVMALDFKGKEGVATSIGHSPISGLIDPVAGSRNSITEALTNIIWAPLKDNLKSVSLSANWMWPCKNEGEDARLYEAVKAISEFAIDLGINVPTGKDSLSMKQKYADGDVISPGTVIISAAGNCSDITKVVEPVFQKDAGAIYYINLSQDDFKLGGSSFAQINSKIGSEAPTVKSAGYVKTVFDTLQELIKANKIVAGHDVASGGLITTLLELCFADNNLGASLNLTELGETDSFKILFAENSGIVFQSVDASVEEKLSEANIAFFNIGHVLESDLLNIINGDESFALTISDLRDTWFKTSYLFDQKQTANNLAKARFDNYKNQALDYKFPQNFSGQISFPTGATADAAHTDAAHTDDAHTDTARTDMARTDAARTDTARTDKSRLVPTTRIDSKENRPKAAILREKGSNSEREMANALYLAGFEVKDVHMTDLISGRENLKDIQFLGAVGGFSNSDVLGSAKGWAGAIKYNETANKVIKDFFEREDTLSIGICNGAQLFMELDLINPEHDAHGKLTYNDSHKHESGFTSVDIQENNSVMLKSLAGSRLGVWISHGEGKFKFPKQEHEYDIVAKYGYEAYPANPNGSHYNTAMLCDKTGRHLVTMPHIERSTFPWNWAHYPKNRSDDKVSPWLEAFVNAKNWILKSKVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMN6</accession>
    <name>A0A5C6ZMN6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Zinc carboxypeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_04170</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00631">
        <property type="entry name" value="Zn_pept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022923176" evidence="1">
        <location>
            <begin position="20"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M14" evidence="2">
        <location>
            <begin position="37"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="827" mass="93417" checksum="C60B22ADD011FEF5" modified="2019-11-13" version="1">MRQFILAVVLLFIQFSIQAQELQSPSAFLGYELGTQFSRQSQVVDYFEQVQKATPQQVKLQYYGKTNERRPLLLAFVSSEENLKNLEQIRENNLKHAGVAQGNSEANNIAIVWLSYNVHGNEASSTEAAMNTIYKLLTEKQEWLKNTVVIIDPCVNPDGRDRYVNWYNETASLPYDKDQQASEHQEPWPGGRPNHYLFDLNRDWVWATQVETQARLKVYNQWLPQIHVDFHEQGIEKPYYFAPAAAPFHEIISDWQRDFQTEIGKNNAKYFDQNGWLYFTRERFDLLYPSYGDTYPTYMGAIGMTYEQAGHGRAGLGIMTDEGEELTLIDRLKHHTTSGLSTVEMASKNAAKLNLEFAKFFDNSALQTKSYVLQGNADKIERLTQLLDKHAISYGFAQGGSVSGYDYASNNEGKRSTDSEDLVVSTNQPKGKMVKVLFEAQTKLVDSLTYDITAWSIPFAYGLDALASKSLIPTSTLGKSPQLNTVSNNATGYIFKWNSLQDAQFLAELLKANIRVRFTEKPMDTQGAVYNRGSLIVIRGDNKTLADFDAQLLQISNKHQRRLIGIKSGFSTSAPDFGSPDVKLVHPPKIALLSGDYTYSLNYGEIWYFFEQELQYPVTTINTKYLYRSDLSKYDILIMPNGNYSELLNDKLLADLKDWIRAGGKLIAIDAAMRSFVDKEGFGLSLNKQEADSSKVAKKNKLIPYADREREAIKNSITGAIFKTKVDTTHPMAFGYGDDYFSLKLGADSYQLLESGYNVAYLGEDPKSVAGFVGNEAAKKLDNSLVFGEQPIGQGSVIYMVDNVLFRNFWDNGKLFFVNALFYVGAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMN9</accession>
    <name>A0A5C6ZMN9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="69"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="169"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="234" mass="25047" checksum="1B5647CADBE81C2E" modified="2019-11-13" version="1">MNSLFKAITLILISALPLQYCVNTNGNRKAENLNNDSALALLEAVSDGDTNLVTEILGTDPDLEITDGYGRTPLMIATYNADNKIAEMLIAAGSNVNAQDKKLNTPFLYAGASGNLPILKMSIANGADFEIYNRYGGTALIPAAEKGHLEAVKLLTEIPDYPIDHINILGWTALLEAIILSEEGETQIAIVRTLVEAGSDVNIPDKDGITPLEHAKNRSMDKIVGILSKTAANN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMP5</accession>
    <name>A0A5C6ZMP5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transcription termination factor Rho</fullName>
            <ecNumber evidence="8">3.6.4.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">ATP-dependent helicase Rho</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rho</name>
        <name evidence="12" type="ORF">ESY86_04225</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homohexamer. The homohexamer assembles into an open ring structure.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the Rho family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="8"/>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008186">
        <property type="term" value="F:ATP-dependent activity, acting on RNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04459">
        <property type="entry name" value="Rho_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01128">
        <property type="entry name" value="rho_factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01884">
        <property type="entry name" value="Rho"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011129">
        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041703">
        <property type="entry name" value="Rho_factor_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011112">
        <property type="entry name" value="Rho_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036269">
        <property type="entry name" value="Rho_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011113">
        <property type="entry name" value="Rho_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004665">
        <property type="entry name" value="Term_rho"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46425">
        <property type="entry name" value="PTHR46425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07498">
        <property type="entry name" value="Rho_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07497">
        <property type="entry name" value="Rho_RNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00357">
        <property type="entry name" value="CSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00959">
        <property type="entry name" value="Rho_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68912">
        <property type="entry name" value="SSF68912"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00767">
        <property type="entry name" value="rho"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51856">
        <property type="entry name" value="RHO_RNA_BD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6 8" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1 8" id="KW-0806">Transcription termination</keyword>
    <feature type="domain" description="Rho RNA-BD" evidence="11">
        <location>
            <begin position="226"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="55"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="55"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="179"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="344"/>
            <end position="349"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="356"/>
            <end position="361"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="387"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TXD90581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="593" mass="67088" checksum="8ACFF0092646EF45" modified="2019-11-13" version="1">MFEISELKAKKLPELQAIAQKLNVPKYRTLKKLDLVYQILDLQAANPEKVKKEIIEVSSNKDDDKTTASKSSDSKDDSKDAPKKESSKDDSSEAKPVKKPAINKKPRPARERVQSDKKPDHKEQKTEVKDTGSDKSPKAESKEEDAKDTSSKAQPQRKKQDKDTRSKNQKDSKPKPNPRPKSNNDNNNKQPNPRSRERNGNVHSGSNGNQDTRNRYREPDFEFDAIIQSEGVLDIMQDGYGFLRSSDYNYLSSPDDIYVSQSQIRLFGLKTGDTVLGNVRPPKEGEKYFPLIRVSKINGQRPEVVRDRVSFEHLTPLFPQEKFNIAEKQSTISTRIMDLFSPIGKGQRGMIVSQPKTGKTMLLKDVANAIAANHPEVYQMILLIDERPEEVTDMQRNVRGEVIASTFDKEAHEHVKIANIVLEKAKRLVECGHDVVILLDSITRLARAYNMVQPASGKILSGGVDANALHKPKRFFGAARNIENGGSLTIIATALTETGSKMDEVIFEEFKGTGNMELQLDRKISNRRIFPAIDLTSSSTRRDDILLDETTIKRMWVMRKYLADMNPVEAMEFINERFKQTKNNEEFLLSMNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMT8</accession>
    <name>A0A5C6ZMT8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">GxxExxY protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_04490</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026350">
        <property type="entry name" value="GxxExxY"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13366">
        <property type="entry name" value="PDDEXK_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04256">
        <property type="entry name" value="GxxExxY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="124" mass="14547" checksum="535DADB369502167" modified="2019-11-13" version="1">MANILYKDESYAIVGALFDVYNHLGSGFSEIVYKDALEYEFKDRAIPFQREKEYAVAYKDVFLSHKFYADFVVFDKIILEIKSIENLNDKQLSQCINYLKVSQLKLAILANFHKDLLDHKRILL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMV9</accession>
    <name>A0A5C6ZMV9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Putative cysteine ligase BshC</fullName>
            <ecNumber evidence="1">6.-.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1 2" type="primary">bshC</name>
        <name evidence="2" type="ORF">ESY86_04175</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BshC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.-.-.-" evidence="1"/>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01867">
        <property type="entry name" value="BshC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011199">
        <property type="entry name" value="Bacillithiol_biosynth_BshC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10079">
        <property type="entry name" value="BshC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF012535">
        <property type="entry name" value="UCP012535"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03998">
        <property type="entry name" value="thiol_BshC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="533" mass="61912" checksum="1FECE62FB2429188" modified="2019-11-13" version="1">MPTQYIPFRETHYFSSLICDYLDEKEALKPFYNRFPKLENFEGQIAEKQSQFSDGTRNILVKSLMSQYANLKISALTLSNLDLLKEHTTFTVTTGHQLNLFTGPLYFFYKIISTINLCKQLKKEHPDHNFVPVYWMATEDHDFEEINFFNFDGKKVQWNRDASGAVGELSLDGLEAVFEAFGKELNTTENANELKRLFSKAYLEHHNLTDAMRYLVNTLFKAYGLVIVDGNDANLKQVFAPFMKAELKHKTTFEQVEDSSAKLNDLSANYKTQVNPREINLFYISKGLRERIVKIENHYQVLETNIKWTETEILAELEKHPERFSPNVVMRPLFQEVILPNLCYIGGGGELAYWLQLKSSFETQNVVFPMLLLRNSVLLVNEKQQKKLDKLEVSIEDLFLKTSDLKTKVTKQISTIDIDFSTQKTQLEQQFKELYSIAEQTDKSFKGAVAAQETKQIKGLEHLESRLLKAQKRKLDSYLARVTDLQEQLFPNHSLQERQMNFSQFYLEYGEAFLLKLRDELNPLHGEFAVITI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN28</accession>
    <name>A0A5C6ZN28_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glucose-1-phosphate thymidylyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_03175</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023917">
        <property type="entry name" value="Bifunctiontional_GlmU_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13562">
        <property type="entry name" value="NTP_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03991">
        <property type="entry name" value="alt_bact_glmU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="393" mass="44015" checksum="2112EB5635C9C188" modified="2019-11-13" version="1">MNYILFDGPSRNDLLPFTFTRPVADIRLGIMTIREKWELYLGTTTTTLTEDYLSEKHPMVEMDENVMINAAFCPNQELVALVQGLSENQAIFKDEDVIAFFTKDTQEHIDFESFEAIEYRESLIKIENTWDIFSLNALAIAEDFEQLTTGRTSQPIPSSNGVMAGQRIFIEEGAKVEFAILNASEGPIYIGKDAEIMEGSLIRGPFALCDHATVRMGAKIYGATTVGPHSKVGGEIKNAVIFGYSNKGHEGYLGNSVIGEWCNMGADTNNSNLKNNYAEVRLWNYNTESFFKTGLQFCGLMMADHSKCGINTMFNTGTVVGVSANIFGSGFPRNFIPSFSWGGHSGFTTYLTPKAFEVASLLMKRRDLEFTEVDKKIMEQVFELTRKYRKSED</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN83</accession>
    <name>A0A5C6ZN83_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">3-isopropylmalate dehydratase large subunit</fullName>
            <ecNumber evidence="12">4.2.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Alpha-IPM isomerase</fullName>
            <shortName evidence="12">IPMI</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Isopropylmalate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12 14" type="primary">leuC</name>
        <name evidence="14" type="ORF">ESY86_02205</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 12">Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>(2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate</text>
            <dbReference type="Rhea" id="RHEA:32287"/>
            <dbReference type="ChEBI" id="CHEBI:1178"/>
            <dbReference type="ChEBI" id="CHEBI:35121"/>
            <dbReference type="EC" id="4.2.1.33"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="12">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 12">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 2/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Heterodimer of LeuC and LeuD.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.33" evidence="12"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00071"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003861">
        <property type="term" value="F:3-isopropylmalate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01583">
        <property type="entry name" value="IPMI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01026">
        <property type="entry name" value="LeuC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004430">
        <property type="entry name" value="3-IsopropMal_deHydase_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018136">
        <property type="entry name" value="Aconitase_4Fe-4S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033941">
        <property type="entry name" value="IPMI_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00415">
        <property type="entry name" value="ACONITASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="SSF53732"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00170">
        <property type="entry name" value="leuC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01244">
        <property type="entry name" value="ACONITASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6 12" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="11 12" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="8 12" id="KW-0408">Iron</keyword>
    <keyword evidence="9 12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 12" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="10 12 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aconitase" evidence="13">
        <location>
            <begin position="8"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="341"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="401"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="404"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TXD90794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="461" mass="50664" checksum="59D5B1CB06937E4B" modified="2019-11-13" version="1">MTKKTLFDKVWDAHVVDTIANGPQILYIDKHLIHEVTSPQAFQELEDRDIPVFRPDQIVATADHNTPTINQHLPIQDELSRKQLEQLSANCKKNNITLYALGHKYNGIVHVMAPELGITQPGMTIVCGDSHTSTHGAFGSIAFGIGTSQVAQVFASQCLLLTKPKSLRVTVNGHLKKGVLAKDVILYIIAKIGTNEGTGYFCEYAGDVFENMSMEGRMTVCNMSIEMGARGGMIAPDQTTFDYVTGREFAPKAETLQNKITYWKTLPTDADATFDKEYHFDAEDIEPMLTYGTNPGMGIKVSGHIPETSDVSFEKSLQYMNFEKGESLIGKPINFVFIGSCTNSRIEDFRVAAEYIKGKQKAQNVTAWLVPGSKQVESQIIAEGLKTIFDDAGFELRQPGCSACLAMNDDKIPQGEYCVSTSNRNFEGRQGQGARTILASPLMAAATAVEGRIVDISKQLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZND8</accession>
    <name>A0A5C6ZND8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">dTDP-4-dehydrorhamnose reductase</fullName>
            <ecNumber evidence="2">1.1.1.133</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_03870</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>dTDP-beta-L-rhamnose + NADP(+) = dTDP-4-dehydro-beta-L-rhamnose + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:21796"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57510"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:62830"/>
            <dbReference type="EC" id="1.1.1.133"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate biosynthesis; dTDP-L-rhamnose biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the dTDP-4-dehydrorhamnose reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.133" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00124"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008831">
        <property type="term" value="F:dTDP-4-dehydrorhamnose reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019305">
        <property type="term" value="P:dTDP-rhamnose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005913">
        <property type="entry name" value="dTDP_dehydrorham_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029903">
        <property type="entry name" value="RmlD-like-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10491">
        <property type="entry name" value="PTHR10491"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04321">
        <property type="entry name" value="RmlD_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RmlD_sub_bind" evidence="3">
        <location>
            <begin position="9"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU364082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD90513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="277" mass="32129" checksum="D042BB24ECA5B90B" modified="2019-11-13" version="1">MSTFDNKHRILILGASGFLGNAIYRELCAYFKTFGTYRVAKKSFEDNRQFFQYNVEEDDVYELLETTKPSIIISCLRGDFHAQVMAHQHIGEYLMRHECKIIFLSSANVFDAYSKYPSYELDKTFSGSIYGHFKIKIENMLLRLPKKKVAIVRLPMVLGAQSPRLKELKQHLEDKTAIEVFPNIIMNVTTDSKVTQQIHYIINRDETGIFHLGSTDLVHHDEYFKDIVNQMAQSNGVIYKQVYTTNEDRYLAVLPKYNKLPKHLQVTSDQVLADLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNS9</accession>
    <name>A0A5C6ZNS9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SAM-dependent chlorinase/fluorinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_01160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SAM hydrolase / SAM-dependent halogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002747">
        <property type="entry name" value="SAM_Chlor/Fluor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023227">
        <property type="entry name" value="SAM_OH_AdoTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023228">
        <property type="entry name" value="SAM_OH_AdoTrfase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35092">
        <property type="entry name" value="PTHR35092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01887">
        <property type="entry name" value="SAM_adeno_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006779">
        <property type="entry name" value="UCP006779"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101852">
        <property type="entry name" value="SSF101852"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102522">
        <property type="entry name" value="SSF102522"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00024035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="285" mass="32065" checksum="4501BD6FB1DAB2D7" modified="2019-11-13" version="1">MAIITLTTDFGEKDHFAGATKGAIYSELPDVKIVDISHSVSPFNVPEAAYIIQNAYSSFPKGTIHLIGIDSELNPENKHIAIYLDEHYFICANNGIMSMICAEIAPEKIVEINIHDRIATSFPVLDVFVHVACHIARGGTLEVIGKVIDTIKPITNLIPFVNDDKNQIIGSVIYIDNYGNVITNIKRKFFESVRRTRDFEVFARSYKFNIIYDRYCDIVNFETPEDKRQDQGRRMAVFNSSGYLEIAVFRGDTKSVGSASSLLGLKLFDTITVNFEPLQTLLRKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZP42</accession>
    <name>A0A5C6ZP42_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">VOC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_01605</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="18"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="135" mass="14759" checksum="32CE4450B0762786" modified="2019-11-13" version="1">MGGVSSTKKKEDKSVKDFISWFEIPAVNFQQAVDFYNHIFKMEMDKNFEGNYAMAFFPVNKGIGGAIVAGPGSTPSDSGILIYLNAGKDLNQVLKRVEPAGGRIIMSKTLINKESGYFAIFIDSEGNKLALHSNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPA5</accession>
    <name>A0A5C6ZPA5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycoside hydrolase family 15 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_03755</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011613">
        <property type="entry name" value="GH15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045582">
        <property type="entry name" value="Trehalase-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19291">
        <property type="entry name" value="DUF5911"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00723">
        <property type="entry name" value="Glyco_hydro_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5911" evidence="2">
        <location>
            <begin position="9"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_15" evidence="1">
        <location>
            <begin position="223"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="601" mass="69556" checksum="97A03062E1995C4D" modified="2019-11-13" version="1">MKDNLNYGIIGNCKSAALISKHGSLDWCCLPEFDSSSVFAKLLDEKIGGSFGVIVADDYEISQTYITDTCILKTRFASEANIFEILDFMPRYKKENGEYYAPPEVIRYFKLIKGQPKFKINYDPKLEYAVGKTSTYVKTHFIVSLTDKGRYDTLFLYTDFDKEAVVNGEELTLKADGFFRFGYNEKLFEPSISIMNLELERTKVYWLNWMQRTPSYKNYNAEISRSALTLKLLSYEKTGAVLAAATTSLPETIGEVRNWDYRFCWIRDASMVIKVVSQLGHKRMAKRYLKFIVDLIPHKDEKLQIMYGINGEKKLTEKKLDHLSGYMNSKPVRIGNAAYSQRQNDIYGILMDVIHQQLVKFEMDVENGEELWTITKGIVWVVDKHWQEADKGIWEFRTEDRHFTFSKVLCWVAVDRAIKVAKILGKTHKLEKWQPLEAEIKKDILDKAWNEDVQSFTQSYGSTDLDASTLLMEPYGFIDAKDPKYMYTVKAIEKELSNDGLLYRYKNKDDFGLPSSSFTICTFWFINSLYKIGETQKAKKLFDQLLSYSNHLGLFSEDIDFETKRLLGNFPQAYSHLALIETAINLSNITDEESILESLEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-02-10" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPR6</accession>
    <name>A0A5C6ZPR6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_04155</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015926">
        <property type="term" value="F:glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011683">
        <property type="entry name" value="Glyco_hydro_53"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07745">
        <property type="entry name" value="Glyco_hydro_53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="53" mass="5943" checksum="41401CBA8CB6E60C" modified="2019-11-13" version="1">MPNSVNLFFCWAPDWLAFAGNENTSTQGSACENQCLFDFEHKALPGLDVFEDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZQP7</accession>
    <name>A0A5C6ZQP7_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Release factor glutamine methyltransferase</fullName>
            <shortName evidence="5">RF MTase</shortName>
            <ecNumber evidence="5">2.1.1.297</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">N5-glutamine methyltransferase PrmC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Protein-(glutamine-N5) MTase PrmC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Protein-glutamine N-methyltransferase PrmC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">prmC</name>
        <name evidence="7" type="ORF">ESY86_01090</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-methionine = H(+) + N(5)-methyl-L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42896"/>
            <dbReference type="Rhea" id="RHEA-COMP:10271"/>
            <dbReference type="Rhea" id="RHEA-COMP:10272"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30011"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61891"/>
            <dbReference type="EC" id="2.1.1.297"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.297" evidence="5"/>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102559">
        <property type="term" value="F:protein-(glutamine-N5) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036009">
        <property type="term" value="F:protein-glutamine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018364">
        <property type="term" value="P:peptidyl-glutamine methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02126">
        <property type="entry name" value="RF_methyltr_PrmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004556">
        <property type="entry name" value="HemK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040758">
        <property type="entry name" value="PrmC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019874">
        <property type="entry name" value="Release_fac_Glu-N5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17827">
        <property type="entry name" value="PrmC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00536">
        <property type="entry name" value="hemK_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03534">
        <property type="entry name" value="RF_mod_PrmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PrmC_N" evidence="6">
        <location>
            <begin position="28"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="5">
        <location>
            <begin position="125"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="203"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD91213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="299" mass="34070" checksum="EEA04D200E8A32AD" modified="2019-11-13" version="1">MILKDILNIYHKELDLHYGKEEVDSFFNLLIEHYLKLKRITMLMNPGFVVTKTEEQPLFEALAALKLQKPIQHIIGETEFYGLPFKVNRHTLIPRPETEELVAWIIEDYNANQDNAEALTILDIGTGSGCIAIALAKQLSASSVYAVDVSEEALKMAVENAKVNEVKIEFGNMDILEPDHRNLPAGRQGLEFLNLKFDIIVSNPPYVRQLEKELMQANVLDHEPHEALFVEDGNPLLFYRAICELAQAKLKPGGSLYFEINEYLGDEMVQLLKSFHFEDIELKSDIFGKPRMIKAVKND</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZRR7</accession>
    <name>A0A5C6ZRR7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">T9SS type A sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_01460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="404"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="824"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="832"/>
            <end position="848"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1556" mass="164115" checksum="0218B8C9ED9B12D9" modified="2019-11-13" version="1">MSNFTKTAGDVKVRRANKDVWCCSTGLLTRFSKSMKAIAFVMLFMFSYGTTLAQEKPIELAKNALRTLVQETSRCGETGRCGEAINGCISDAPDAPTAEEVQIQLQPILFASVGTIFVTHAESVAGDNCEWTITHTYTVTCDDGFLFDLPIEYFGGDDIAPVVATEETGGDLGCNPDMPSPIFTATDNCSDLIEVMVTFGPIQEDGCFRSQTFTATAMDFCDNEAEPVSVTYTWTQDTEAPLIAAGDGGDLGCNPEVIPFPEFTATDNCGQIEPSVEVGDVVADGCSMSQTFTATAVDGCENQAEPVSVTYTWTEDTEAPVIEASEGGDLGCNPEVIPTPDFFATDNCGLVEVDIDTDGPEQLDECSWTQTYTGTTVDACGNQAEPVSVTYTWTIDTEKPVITLASDGDGDGDGDGNGDGDGEDCTGSFVISYSPGGTKSGNPIAGNRMDPTKALGAPQNDNSLNFVSLGYGGEIVIGFAGQVANNPGNDISVLETSFGDVSFDIYPESADIYVSMDGVTFYLIGTDFTNIFGNYDISNASATLPYITQVKIIDTTPAGSVSEDGYDLDGIVALSGCPTGSGDPDNDLGCNPSTEDLNPTFIVTDNCSEGVATVTTEGPMADEDGCGFSQTFTANYTDDCGNVADPVSVTYTWTVDLELPVIATDAEDMDLGCNPEEGEFGMPSFTVTDNCTAELEANVEAGNLIEDGCFRSITYTATAQDECGNNAEPLSVTYTWTSDNEAPVITPLEDVVLECNPGEFDFPVFEATDNCEVDMPTVTPGEIMVDGCNWSQIFTADVTDACGNIAEPVTVTYSWTVDTEVPVISLGTDGDGDGDGDGDGDGDGDGDGEDCNGSSVISYNPGTTKSGGAIAPDRMDPTKGLGAPQNDDTLNFVTLGYGGEIVIGFPGRVYNNSGNDISVLETSFGDVDFSEYPESAEVWVAMEDGVFYQIGQDVTNAFGDFDISDASAPLPYITQVKLLDNTPAGSTSQDGYDLDGIVAINGCSDSSGDNDNDLGCNPSVEDIEAPNFVVSDNCSEGEAIVTTEGPVADVEGCGFSQTFTANYTDDCGNAAEAVSVTYTWTEDLVAPVIMTAAEDMDLGCNPEEGAFTMPSFDVSDNCIAEIAADVATGDIVMDGCFRSITYTATAQDACGNDAEPVSVTYTWTMDNDDPTIDVAAEPLMLECDGEGNVDGINTYLANHGYAEASDACGDVEWSHEVGGPVGTNCDVTIEVTFTATDGCGNTASTVGTITITDSQGPAFDEIPDNVIVQCIEDVPAPADITATDVCSGDAMVASSDSSEGDDCNLTITRTWVATDVCGLTTEYDQIITVADTTAPVIACPDSSEDDRIVIDPSIDCTDSFAIVDFLNVQLEDNCSPTKDAVPSYIVRVSDLYNTLPDGSIVVLGTLTYAAGHNVDDCGNVAEDDCVVYFEYIESPSDSGGLKSADICKTTEYFDGRARVSERCNGLEVTDVAFTAYPVPFENEINIGYSFDYDTKIAIKVYDTRGVVVSEVNTDNYIAGTKGNTTIDLSRVATQMLYVKLETDRGEMIKKIVSSGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZA59</accession>
    <name>A0A5C6ZA59_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_20800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000130">
        <property type="protein sequence ID" value="TXD85775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD85775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="167" mass="20004" checksum="53FF463F8F014873" modified="2019-11-13" version="1">MSEKYGIQLNNDRIELGLKPITDNWALDSIVLQVPARGMNCFPSEIPDTTNYRFLENKWYCQYWTNKEIDKTKPYHKSKKIYFTKSFWIWQNEIDFEYDNFINPNSNPAEYEELEMSTHWQRNGEIYGHLAHMKNGEDLLIDDDVNQSMYGFDKEKVITILEKWGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZB12</accession>
    <name>A0A5C6ZB12_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tyrosine-type recombinase/integrase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_20590</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000090">
        <property type="protein sequence ID" value="TXD86124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="2">
        <location>
            <begin position="70"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="254" mass="29081" checksum="039667FE102FE466" modified="2019-11-13" version="1">MAHLALHHKRSPETLSVENIEAYLYHCQKLHRTPSESFFKHTIFGLRAAYKVMGMEAKRVALPQIKRDLKLPIVLSQEEVKRLLKAPRYLKHRLIIGMLYGCGLRSYELCGLKLADIDFDRRTVFIPKKKGKIDRYVPLSKHLIRGLKKYLRTENPQIYLFNSQVTKDGKARGLTTNGIGWVIKESRGKIGSSKKITAHTLRHTFATHLLEYGVDIVSLKELLGHAHIEMTLTYLHVANLPSGSRFSPLDKLYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZB58</accession>
    <name>A0A5C6ZB58_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 9">Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex</fullName>
            <ecNumber evidence="5 9">2.3.1.61</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">2-oxoglutarate dehydrogenase complex component E2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">odhB</name>
        <name evidence="13" type="ORF">ESY86_19260</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 9">E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2-oxoglutarate to succinyl-CoA and CO(2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>(R)-N(6)-dihydrolipoyl-L-lysyl-[2-oxoglutarate dehydrogenase complex component E2] + succinyl-CoA = (R)-N(6)-(S(8)-succinyldihydrolipoyl)-L-lysyl-[2-oxoglutarate dehydrogenase complex component E2] + CoA</text>
            <dbReference type="Rhea" id="RHEA:15213"/>
            <dbReference type="Rhea" id="RHEA-COMP:10581"/>
            <dbReference type="Rhea" id="RHEA-COMP:10582"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="ChEBI" id="CHEBI:83120"/>
            <dbReference type="EC" id="2.3.1.61"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
        <text evidence="9">Binds 1 lipoyl cofactor covalently.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">Amino-acid degradation; L-lysine degradation via saccharopine pathway; glutaryl-CoA from L-lysine: step 6/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 9">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.61" evidence="5 9"/>
    <dbReference type="EMBL" id="VORO01000038">
        <property type="protein sequence ID" value="TXD86793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00868">
        <property type="reaction ID" value="UER00840"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045252">
        <property type="term" value="C:oxoglutarate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004149">
        <property type="term" value="F:dihydrolipoyllysine-residue succinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033512">
        <property type="term" value="P:L-lysine catabolic process to acetyl-CoA via saccharopine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006255">
        <property type="entry name" value="SucB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="SSF47005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01347">
        <property type="entry name" value="sucB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 9" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="11">
        <location>
            <begin position="2"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="12">
        <location>
            <begin position="140"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="77"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="81"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00019511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TXD86793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="427" mass="46123" checksum="7977788F938E909D" modified="2019-11-13" version="1">MILEMKVPSPGESITEVEIADWLVSDGDYVEKDQAVAEVDSDKATLELPAEASGIITLKAEVGDAVEVGAVVCLIDTEGKKPGGSSDKKASDKSEEEASKKEEKSSDASAEKKESSSDKPKKEDSEKKEASSDSQKSAGVASPAAKKILAEKDMQATSVKGTGKDGRVTKDDAVNAKHSMGTPTGGKRGESRSKMSMLRRKVAERLVEAKNTTAMLTTFNEVDMKPIFELRKQYKEDFKSKHGVSLGFMSFFTLAVVRALEMYPTVNSMIDGKEMISYDFCDISIAVSGPKGLMVPVMRNAENLGFRGVEEEVKRLAIRARDGKITVDEMTGGTFTISNGGVFGSMLSTPIINPPQSAILGMHNIVERPVAIDGHVEIRPIMFVALSYDHRIIDGKESVGFLVAIKEALESPEALLMDGDVKRALEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZB91</accession>
    <name>A0A5C6ZB91_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19960</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000053">
        <property type="protein sequence ID" value="TXD86527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="337" mass="37150" checksum="B3AA84CDAFCE5A03" modified="2019-11-13" version="1">MVSSATQLNVSGIESPQQELTEWKNLQKQQNNNAKLNNKASIVLNGLFFNYSKININALSNNKISVVNDKYINGIWQNPYDNKLSFAIVSPVFAISKSNVEVKLPTTLWHSNTAITDIAIDFGNNTGYKNLSNGNLASTNYTNIGTYTWTYRVRLSNGQYKYCRQKVKVTQVDNNNAQARKPNCAIQEEPITSTKSFQGVFGSATLQIAYGSANCTMQKPLIVAEGLDTGLMGQGGSIGDNDINSFFQSIFQSGSNELENLTINNTAVDYDIIYVNWDSGTDFIQRNAYVLEEVIKWVNDQKALAGSTEPNVVLGQSMGGLIGIPTKSVTIFIKPLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBF8</accession>
    <name>A0A5C6ZBF8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19360</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000039">
        <property type="protein sequence ID" value="TXD86766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="114" mass="13057" checksum="904DDBCAE57F1C70" modified="2019-11-13" version="1">MIIFFGIALVNINLPLNKLRISGTYVSNEREPFLADTPYKSDTLILNPNGSYSSKFYGSGTYAIDYGIFTSKIRLTYRSQFGSASHSLTFSDKVYETQKIMLNNELNHYYEKLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBJ7</accession>
    <name>A0A5C6ZBJ7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_17985</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000029">
        <property type="protein sequence ID" value="TXD87119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="66" mass="7590" checksum="9DF55514EF8A74D1" modified="2019-11-13" version="1">MAEYTNVEKPFLEKLRALNWRIIDQGSFGIPQDPAKSLRTSFKEVTLKKEFKKAVKKKIALMALHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBT4</accession>
    <name>A0A5C6ZBT4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">6-carboxy-5,6,7,8-tetrahydropterin synthase</fullName>
            <ecNumber evidence="8">4.-.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">ESY86_20100</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>7,8-dihydroneopterin 3'-triphosphate + H2O = 6-carboxy-5,6,7,8-tetrahydropterin + acetaldehyde + 2 H(+) + triphosphate</text>
            <dbReference type="Rhea" id="RHEA:27966"/>
            <dbReference type="ChEBI" id="CHEBI:15343"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18036"/>
            <dbReference type="ChEBI" id="CHEBI:58462"/>
            <dbReference type="ChEBI" id="CHEBI:61032"/>
            <dbReference type="EC" id="4.1.2.50"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8 10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8 10">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Purine metabolism; 7-cyano-7-deazaguanine biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the PTPS family. QueD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.-.-.-" evidence="8"/>
    <dbReference type="EMBL" id="VORO01000057">
        <property type="protein sequence ID" value="TXD86481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00391"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070497">
        <property type="term" value="F:6-carboxy-5,6,7,8-tetrahydropterin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007115">
        <property type="entry name" value="6-PTP_synth/QueD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038418">
        <property type="entry name" value="6-PTP_synth/QueD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12589">
        <property type="entry name" value="PTHR12589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01242">
        <property type="entry name" value="PTPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006113">
        <property type="entry name" value="PTP_synth"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 8 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 10" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="25"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="9">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="9">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001293"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR006113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR006113-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR006113-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD86481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="149" mass="16921" checksum="F6DE3823B0CED874" modified="2019-11-13" version="1">MSNIRITKQFSFETGHALYGYDGKCKNVHGHSYNLAVTVIGQPIADSDHVKFGMVIDFGDLKKIVKEEIVDVFDHATVFNKNTPHVELAKELADRDHNVLLVDYQPTSEMMVIDFAEKIKQRLPENVQLHSLKLQETATSFAQWFASDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC36</accession>
    <name>A0A5C6ZC36_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Indole-3-glycerol phosphate synthase</fullName>
            <shortName evidence="8">IGPS</shortName>
            <ecNumber evidence="8">4.1.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">trpC</name>
        <name evidence="10" type="ORF">ESY86_16370</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate + H(+) = (1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:23476"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58613"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="EC" id="4.1.1.48"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 4/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the TrpC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.48" evidence="8"/>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00043"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004425">
        <property type="term" value="F:indole-3-glycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00331">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00134_B">
        <property type="entry name" value="IGPS_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045186">
        <property type="entry name" value="Indole-3-glycerol_P_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013798">
        <property type="entry name" value="Indole-3-glycerol_P_synth_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001468">
        <property type="entry name" value="Indole-3-GlycerolPSynthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22854">
        <property type="entry name" value="PTHR22854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00218">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00614">
        <property type="entry name" value="IGPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="4 8" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="7 8 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="IGPS" evidence="9">
        <location>
            <begin position="4"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD87605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="262" mass="29213" checksum="D0E54BC7F73DC25A" modified="2019-11-13" version="1">MDILEQIVKDKHKEVALKKEFIPIKAFEQLPYFTRQTLSLAQRVRDNDPGIIAEFKRKSPSKSWINETADIESIAEGYEEAGVSGMSVLTDEIHFGGTMDDLLMARENCNLPILRKEFIIDEYQIIEAKAIGADAILLIASILTKAEIKAFSELAKSLQLEVLLEVHNEAELQKSIMPSLDLLGVNNRNLKTFEVSLETSKRLSQLIPDYFVKVSESGISSIDAIKSLQPYGYKGFLIGENFMKTKDPGKSAAAFIKALASI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCD1</accession>
    <name>A0A5C6ZCD1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">LacI family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_15995</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000021">
        <property type="protein sequence ID" value="TXD87660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="2"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD87660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="335" mass="37089" checksum="BB759954D5DC7BBB" modified="2019-11-13" version="1">MVTLKHLAEQLSVSISTVSKALNNSDEISPDTIERVKALAKHLNYKPNKLAVSLKKSKTFTIGVIVPNILNHFFAKALYAIEMEATKHGYNIITCLSNETRSKEDNSLQLLSNGSVDGFILSIAEETQIKDNIEHINDILKQNIPIVLFDRVSDLIACDKVIIDDFGAAFEATEYLLKEGRKHIVLIGDIEELSVGKLRTNGYLKALEDASDYSSGPEILSLKRGESAEAQIESLLRDDNSIDGIIAIDNVSGVIALQKAIKHKRKVPKDLSIIGFSDENVLQFTDPKLSTVSQHTFDIGRASVELLLARLEDRTPKTHTTKTIKTKLILRDTTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCJ9</accession>
    <name>A0A5C6ZCJ9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PKD_6 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000066">
        <property type="protein sequence ID" value="TXD86381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045829">
        <property type="entry name" value="PKD_6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19408">
        <property type="entry name" value="PKD_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKD_6" evidence="1">
        <location>
            <begin position="340"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF19408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="531" mass="57139" checksum="A9B3495BA0BEB5B4" modified="2019-11-13" version="1">MKSKIQLLIILITFCTYNTYGQITTEIIDVLVNNQTTVSNCSLIDLEDNSNISLTIYFKLTKPSNQALGTTNVKALLKYSNSSSGDDKGNYTVQSNSWGNNDTEFYGQIPISVSENEIQVNSSSIFIKSITDSGVESNSCEYSLEKDEVPSFSLSPTSTTVSCGNSSPKTFTVTPSNIPSGASVEYQWNVGNGWQDTSGNNVSNFTTTTSSVTLVPFAYPPNNVRVTPVLDGDNYPQLTSTVSLGNFNPSFLEITGNDNVCDSEIYSIVNLPNNVSILGHGSSNNSIATATLDTSSGEITVNKVSDGIITLTVILQNSCSQNFTLTKEIEIGIPTSVFNASIAGNSSVCQGQSYTYTLNSANHPCAGSIVWSVSSNLNIVSQNSNSVTITKNPFSTEYAGEITASFSGSTIEIKKGVWVGVPSNDGLTIQKIGSYNLYAGQWSKLRARYIPLTYESNDLLNITFEWQIPNSMIRNYADTAYKDVKPRSSGQLNIGVRVNCECGNGEWRYRLFDVDGGNGNGGGVLIPVGGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCP2</accession>
    <name>A0A5C6ZCP2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_17075</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the OmpP1/FadL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000025">
        <property type="protein sequence ID" value="TXD87384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005017">
        <property type="entry name" value="OMPP1/FadL/TodX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35093">
        <property type="entry name" value="PTHR35093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03349">
        <property type="entry name" value="Toluene_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022896754" evidence="8">
        <location>
            <begin position="20"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD87384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="505" mass="55895" checksum="9BE35D93E3896E72" modified="2019-11-13" version="1">MKKLSLLIIGVLSMSHSYAQEISDAVRFSNDEVQGTARFRALSGAFGALGGDMSAVSINPAGSAIFARSHASFSLSSLTVNNDVNYFNGFNSSSESKFDLNQAGAAFVFANNDPNSKWKKFTLSFAYDKTANYEDQWYASGTNTRSIDRYFLDYAQGLPLNEISAFSDETISEGYSGIGSAYGFGNQQAFLGYESYILEPAADTDENTVYSSNIGAGTFNQSYDYAATGYNGKFTFNIATQYGETLYLGLNLNSHFINYERFTNFTEFNNNAGSLVTDVDFENSLATRGNGFSFQLGAILKVTNELRAGFTYQSPTWYTITEETTQYISTVRNGQNGFETVMVDPNVVNVFPDYNLKTPGKITGSLAYVFGDKGLLSFDYSRKDFSNTQFRPTSDPFFASQNNLMNNALQASNTYRLGGEYRYKRVSFRGGYRFEDSPYKNDSFYGNLNGYSAGLGYKFGSASLDFTYDYAERTINNRLFEVGLTDAAILDTNNSNFTLSLGFSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCU1</accession>
    <name>A0A5C6ZCU1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Colanic acid biosynthesis glycosyltransferase WcaL</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_16870</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000024">
        <property type="protein sequence ID" value="TXD87451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="3">
        <location>
            <begin position="30"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="2">
        <location>
            <begin position="226"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD87451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="410" mass="46509" checksum="848BA8AA05E8E62F" modified="2019-11-13" version="1">MKNSISIVIKTGSFPAVSETFIVSNIVCAIKRGFQVNIIAPNKIQECATSQPQLLTQYQLLEKTKYFKSPVKSYKRILFAVYCLLNPLVFFYFLKYSWNYRIVHLKTLYRIYYYLPYRKADICHVHFANNAGELPALKKIGYIKSKLLITFHGHDAFYANAKQQRKLKHNYNLLFKYADRITVNSIYLKKLVLNLGCPEFKLRVVPVGVDVNLFSPEFLPKILDISQPIQLLSVGRLVEIKGHEFGIRAVRVLIERGFSVKYTIIGEGALMQKLKALTVEIGVEDHVNFFGGGSQMDIRKAYTKSHFFLMTSVMDASGREESQGVVTAEAQAMGLPIVGFKSGGVPFTISDETGILVKQKDFEALANAISSLISLPKTYETMSVSARKWILDNFNLDTMVAHYYEDLISK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCW0</accession>
    <name>A0A5C6ZCW0_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Translation initiation factor IF-3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">infC</name>
        <name evidence="7" type="ORF">ESY86_18765</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the IF-3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000033">
        <property type="protein sequence ID" value="TXD86968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00080">
        <property type="entry name" value="IF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036788">
        <property type="entry name" value="T_IF-3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036787">
        <property type="entry name" value="T_IF-3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001288">
        <property type="entry name" value="Translation_initiation_fac_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019815">
        <property type="entry name" value="Translation_initiation_fac_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019814">
        <property type="entry name" value="Translation_initiation_fac_3_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10938">
        <property type="entry name" value="PTHR10938"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00707">
        <property type="entry name" value="IF3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05198">
        <property type="entry name" value="IF3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54364">
        <property type="entry name" value="SSF54364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55200">
        <property type="entry name" value="SSF55200"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00168">
        <property type="entry name" value="infC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 7" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IF3_N" evidence="6">
        <location>
            <begin position="18"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="IF3_C" evidence="5">
        <location>
            <begin position="93"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF05198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD86968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="181" mass="21122" checksum="9DDDB270D8106475" modified="2019-11-13" version="1">MRRRNYSKRVKQEDQHKINSKIRAENVRLVGDNVEIGIYPVKDALKIADEQGLDLVEISPNADPPVCKVMDYKKFLYEQKKREKVLKAKASKVTVKEIRFGPQTDDHDYEFKKKHAEKFLKDGAKLKAFVFFKGRSIVFKEQGQILLLRLAQDLEELGKVEQMPRLEGKRMTMFIAPKKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD23</accession>
    <name>A0A5C6ZD23_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GNAT family N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18510</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000032">
        <property type="protein sequence ID" value="TXD86988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="170" mass="19794" checksum="63BB8676DAD3A16F" modified="2019-11-13" version="1">MIEIKKYTELSEKLRNQLSSYIEDEFGHIPIVKETEWETPNLTIIFYDNEQIVTFYNIVLREISIDNKKIKIAGLNNVMTPKEFRGMGYASIVLREIENLIFTSLSCEMGLLLCADALIPFYEKFNWYKIDCPVYFEQSSGVKLWGASTMLLTRDEKICADKIELNGLPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD38</accession>
    <name>A0A5C6ZD38_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19670</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000045">
        <property type="protein sequence ID" value="TXD86642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023146105" evidence="1">
        <location>
            <begin position="20"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="93" mass="10244" checksum="CE545F490A13A492" modified="2019-11-13" version="1">MKNVFFALAFMLVGTLTFANNVEVETIDNNVTIENVLSLDEVSLEEVALDDAMACGFPLSWDTGEHGTGSFYFGCDDSTTMDDILSVIFALFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD64</accession>
    <name>A0A5C6ZD64_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase_M43 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_19560</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000043">
        <property type="protein sequence ID" value="TXD86688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008754">
        <property type="entry name" value="Peptidase_M43"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05572">
        <property type="entry name" value="Peptidase_M43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022851752" description="Peptidase_M43 domain-containing protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M43" evidence="2">
        <location>
            <begin position="167"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="792" mass="87613" checksum="3207D4381866511A" modified="2019-11-13" version="1">MKNKLILLTLALFIFSNVKSFGQELCQTPSQTNNEILNKSALLRTSSNDNSYCLKIYFHVIRRSDGTGGQTVAAVNQAFQILNDDFYPHNISFAWDNSIDYIDDTSLYNSPGATIYSVNNHQDGIDIYLFSNDLSPGAGGANGIGGSSEMYVHGTFGQPPFQSLITSHIVSHEMGHVLFLWHTFRGTNIPELENGDFCPELVDGSNSDICGDYVTDTPADPNMTYNVDASCQWLGSGTDANGDSYDPDEQNIMSYSTPQCMSYFTPLQGLRMRNAIATLPFLQQTLESCCEEPLDLYIKDSPDDNGTEPNPTSQNMWTSQDIWIRNNDDGGLEHQNPEYTNSGVFSVPNYIYVKVINNSCEASSGNETLTINWAKANTALAWPQNWNGTLTDDDDNNADPTDGGGDPLGGVLSPVTIPALQSGEETIVAVPWVVPNPDDYSDNDDPWHFCLIARIDATDDPIGTYTSNPNVMVRNNNNQAWKNITVVDLVEDGRSGSVMIANPSNTPRTFFLELHKESNEDGKPIFDEAEVTIKMDDVLFNAWERGGKLAQELDPTSEEKKKLIKGDNVILDNIAFEGNEMGLLTLYFNFLTEELTDKTEYNYHVIQKDATTGEIMGGETYVVRKDSRTTFLADAGGDKEVDVNETIVISAEDINEPAEYNWYDSFGNLVYQGKDLTVIADVVKQYKLEVIAASDGFKDYVDVEVKFKPSSIDGLSPNPVSNNVTVNYKINDTNSAYLMVIGYYGSNTSNNYILDTDLQQTQIDTSNYPTGHYTVALVCDGEIVDAKTLIKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD70</accession>
    <name>A0A5C6ZD70_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sugar transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_16935</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial sugar transferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000024">
        <property type="protein sequence ID" value="TXD87464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003362">
        <property type="entry name" value="Bact_transf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02397">
        <property type="entry name" value="Bac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="Bac_transf" evidence="3">
        <location>
            <begin position="10"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD87464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="195" mass="22180" checksum="397053660C2E84ED" modified="2019-11-13" version="1">MINSKQLLVKRGFDLLLGFALLPFLVIPVVLLVVLATVDTRCFGWFAQERVGQHGRLFRMFKIRTLRVEPHALGDLDASASSFGRFLRRYKLDELPQLFNVLFGQMSFVGPRPDVPGFADALKGADRMILKVKPGITGPASLKYQHEAQLLAQQAQPEVYNREVIWADKVKINKAYVETYRFSLDLRLLLKSIFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD93</accession>
    <name>A0A5C6ZD93_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_18060</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000029">
        <property type="protein sequence ID" value="TXD87142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="91"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="211"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="247"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="279"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="310"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="339"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="365"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="1"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD87142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="395" mass="41908" checksum="B35D47E2F52E2969" modified="2019-11-13" version="1">MADAIGNSFLIIVLPLYIASGKVEGDFFGFSESLITGIVLGLYGLVSSFFQPLSGRISDKLGKRKLFVLAGLFIFMIANFAYTFASNYTLLLVIRAVQGFAAALTITATLALVSEVSSTKNRGGNMGVYNAFRLVGFAIGPLGSAALVENGPYNLPFIGEASGFTMAFMLAALAALLSLILVAVFVKDPEDTKPNKERMIIRFRSQEPGRFLDPIFTLGIATLFMSMGFALLAPIELVVNERLSQGAFLFSIQFSALIVSMAILQPIIGKASDKYGRKIFIVVGLVCLIPIIVFEGLATEPWHMITARSLHGLSAAMVFAPALALAGDLAKKGQVAAQLSILTVAFGLGISFGAFLAGFSIRFGFVVPFIIAACLAAIGAILVKTQVPSSQTAEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDJ0</accession>
    <name>A0A5C6ZDJ0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">BlaI/MecI/CopY family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_16650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BlaI transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000023">
        <property type="protein sequence ID" value="TXD87523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005650">
        <property type="entry name" value="BlaI_family"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34134">
        <property type="entry name" value="PTHR34134"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03965">
        <property type="entry name" value="Penicillinase_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019455">
        <property type="entry name" value="CopR_AtkY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="130" mass="15231" checksum="C7E44A7B05DFE0AF" modified="2019-11-13" version="1">MQKLTNKEEEIMHILWKLENAFVKDVLAEIEEDKPHYNTLSTIIRNLEEKGFVSYNAFGKTHQYYPIVSKEAYRARFMSTAIEHYFNSSYKNLVSFFAKEEKISVDELKEIIALIETKNTAANTSEDKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDK1</accession>
    <name>A0A5C6ZDK1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">WYL domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_16705</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000023">
        <property type="protein sequence ID" value="TXD87533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026881">
        <property type="entry name" value="WYL_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13280">
        <property type="entry name" value="WYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WYL" evidence="1">
        <location>
            <begin position="135"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="326" mass="38713" checksum="BFC1714B0BA590A3" modified="2019-11-13" version="1">MTPEFLRRYYILRVISNSKVYGIEKNGFVPLSDLRNVLDQLRLDNIDDPLYDKLNQYSQKTIKRDLEKIKSYYQAVILHKRNYGYYIEAYEVSEALKDVYEKTEIYLLHHHAHAWKAHVTTSRSSLSSQVDLVPLIHAIEQQFFIELEYQGWYDDDGFQTIAGFFQPLHLKEINKAWYLMAHNEQHGVYTFCLDDRIKSLKINKQPTKQPITFNPFEHFKNTIGVLKTGMPAEWIHIQVANHHFKYLTNNPLHHSQKIVARPKAIDTDDLDYGNPDIWGEIKVYLEPNYEFLMEILKYNLWVKVISPLHARDFVKQHLDLMMGYYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDP6</accession>
    <name>A0A5C6ZDP6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19350</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000039">
        <property type="protein sequence ID" value="TXD86764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="129" mass="14473" checksum="DB8AE983D060CAFB" modified="2019-11-13" version="1">MRQLKISGFKIKFKKSTCDQTRAFPINSFFSSQLTAHSSQLTTHSSQAHNSQLTTHNPIFGILVPFSPNIYRQGQEHDAENSINFALTLKGIIGFSRIETTPENSINFALTLKGIIEFSGIETTQNIWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDQ7</accession>
    <name>A0A5C6ZDQ7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">F0F1 ATP synthase subunit epsilon</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_13700</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ATPase epsilon chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12152">
        <property type="entry name" value="F1-ATPase_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001469">
        <property type="entry name" value="ATP_synth_F1_dsu/esu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020546">
        <property type="entry name" value="ATP_synth_F1_dsu/esu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036771">
        <property type="entry name" value="ATPsynth_dsu/esu_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02823">
        <property type="entry name" value="ATP-synt_DE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51344">
        <property type="entry name" value="SSF51344"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="5" id="KW-0139">CF(1)</keyword>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATP-synt_DE_N" evidence="6">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD88150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="97" mass="10370" checksum="EDDA81C51EF7A59A" modified="2019-11-13" version="1">MYLEIVSPEATLLSSDVESVIVPGIDGEFQLLNNHAAIVATLAEGTIKIKLSNASAIDMEELHALVIPSTTDAKTLTVKIHSGTIEMKDNKVILLVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDQ8</accession>
    <name>A0A5C6ZDQ8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF58 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15955</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000021">
        <property type="protein sequence ID" value="TXD87681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002881">
        <property type="entry name" value="DUF58"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01882">
        <property type="entry name" value="DUF58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF58" evidence="1">
        <location>
            <begin position="179"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="423" mass="48987" checksum="77840546968849BE" modified="2019-11-13" version="1">MILFVLSFVFPRLFNIVKLLLLLLATLTLLDSIILFSAKRGVVGRRLLPEKFSNGDENPIELAISNYYTFKVYVKIIDEIPEQFQVRDFEILRDLEASSTSQIEYKLRPVARGEYHFGTLNIYVSSVFGLVARRFKTDTDAMLPTYPSFMQLRKYNLMAISNNLHQYGIKKIRKIGHTMEFEQIKDYVLGDDLRTINWKATAKRNQLMVNQFQDEKSQPIYSVIDKGRIMKMPFDGLTLLDYAINAALVISNVALKKHDKAGILAFSKRVENIVVAERRASQMNLILETLYNVNTDYFESDFSRLYADVKRNIKQRSLMLLYTNFETLDGLHRQIPYLKGIAKNHLLVVIFFKNTELDSIINNKSETVQQAYDKVIAEKFAFEKRLIVNELQKFGIQSILTTPKDLTLDTINKYLEIKARGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDR6</accession>
    <name>A0A5C6ZDR6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Esterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_13755</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000801">
        <property type="entry name" value="Esterase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00756">
        <property type="entry name" value="Esterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022847832" evidence="1">
        <location>
            <begin position="20"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="392" mass="45038" checksum="03809B9F723B1099" modified="2019-11-13" version="1">MKRVLLFTCALLFCGTVLSQMKREQFESRKLNATRELKIQLPDNYDPESDLKHPVIIVFDGEYLFEPVSGQVSFQTHFDEMPESIIVGIIQGKERFYDSYFDEVTGLPIESGKRFYDFVAEELIPYLDAKYNTSKFKVAVGHNLMGNFINAFLFSKEPVFDSYINLSPDFKGSMGVNVAKRLAFLDNEIFYYLATSDGDISHINASIHETNTAIKAVDNKALTYYFDELKGDSHYTLVTGALSKAMDKIFELYKPLDDKEIEEKIMPYEGTLDDYITDRYNRIDDLFGIFKPISEEEFEKLIEIANRREDLESVYKIGKLANAQNPNSAFGTYYMAQYAEKNGKTKKAVKLYESALVLEDMSHIDKEFIMTHIEGLKVVEDDTEIDEEDGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE71</accession>
    <name>A0A5C6ZE71_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_17190</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000025">
        <property type="protein sequence ID" value="TXD87409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="118"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="184" mass="20687" checksum="620AD9A4A4073310" modified="2019-11-13" version="1">MKKDNIKDLFKRLEGGFDVESPNEGHQQRFLDKLNEVSKVQVLPSSSTFNFWKPLLAIAASLLIGLAIFTTLDKEPAIDGLASVSPELSETQDFFNAAISQELNNLNSKRTPETEALINDALKQISLLETDYNKLKMDLKESGNDKRVVYAMISNFQNRIELLQNVMAHIEDAKNMSTETPNIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEI9</accession>
    <name>A0A5C6ZEI9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acyl-CoA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000062">
        <property type="term" value="F:fatty-acyl-CoA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000582">
        <property type="entry name" value="Acyl-CoA-binding_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035984">
        <property type="entry name" value="Acyl-CoA-binding_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014352">
        <property type="entry name" value="FERM/acyl-CoA-bd_prot_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00887">
        <property type="entry name" value="ACBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00689">
        <property type="entry name" value="ACOABINDINGP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47027">
        <property type="entry name" value="SSF47027"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACB" evidence="1">
        <location>
            <begin position="9"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="88" mass="10516" checksum="09DBCE1301309884" modified="2019-11-13" version="1">MTSEELHIEFEEAVERINSFKEPYPADLLLRLYAYFKKASNDYRRPSSSKPIINAFKTNALFQVKDVTQDEAKRIYIDLVNNYFLYRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZET6</accession>
    <name>A0A5C6ZET6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_16010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000021">
        <property type="protein sequence ID" value="TXD87663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039672">
        <property type="entry name" value="MFS_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11328">
        <property type="entry name" value="PTHR11328"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="217"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="278"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="317"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="347"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="372"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="418"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="459"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="502" mass="55974" checksum="57769C910F4AF2DA" modified="2019-11-13" version="1">MKKEVTPLPDRVPIGQKLSFGAGHLVLNLLPGSLGIFMFFLLTAFGMDPFLAGLLGGLPRIFDAITDPIMGFISDNTNSRFGRRRPYIFVGAILSGILFAVLWQLDPDNSQNYNFWYFLILSMVFLIGNTMFATPLIGLGYEMTSDYNERTRLMAFSQILGQIAWMIVPWFWVIIASPDMLPITAEETARIAQLGLGTEEAAKMTLQSLQANGVRKLSVIVGLICIVLGLLPAIFCRGIDSARMENRKKITLKTLFSNIKDLGEGIKQVSKSKPFVKLCGATFLVFNGFQLVASFSFFIIVFYMFNGDYAAAGNWPAWFSTITAVVTAFLVIPIISWMSDRWGKRTAFVVSTFISIIGYILKWWGFDPDNPWLIFMPIPFMAFGLGGLFTLMMSMTADVCDLDELENGMPRKEGTFGAIYWWMVKLGQALALVLGGLVLKLVGFNQDAITQTADTMTNLRIADILIPSITAGIAIVVMWKYSLNEERAKEIKTELVKRRGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEZ4</accession>
    <name>A0A5C6ZEZ4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative toxin-antitoxin system toxin component, PIN family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_13650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002850">
        <property type="entry name" value="PIN_toxin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34610">
        <property type="entry name" value="PTHR34610"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13470">
        <property type="entry name" value="PIN_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00305">
        <property type="entry name" value="TIGR00305"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PINc" evidence="1">
        <location>
            <begin position="3"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="136" mass="15763" checksum="9B74A5DB2636B9BC" modified="2019-11-13" version="1">MQKVILDTNVIVSALIQKNYPYLILDYCIEGNATICISNAMLQEYIEVLRRPKFAGFIDFKTNADFLIARISEMAETYEPTHKLNIIADEPDNRLLELAKISNANFIITGNTNDFTMKVFEQTKIVSPKKYWEDYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF15</accession>
    <name>A0A5C6ZF15_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">DNA repair protein RadA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">radA</name>
        <name evidence="9" type="ORF">ESY86_13760</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.</text>
    </comment>
    <comment type="function">
        <text evidence="5">Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.</text>
    </comment>
    <comment type="domain">
        <text evidence="5">The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the RecA family. RadA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000725">
        <property type="term" value="P:recombinational repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01121">
        <property type="entry name" value="Sms"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01498">
        <property type="entry name" value="RadA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004504">
        <property type="entry name" value="DNA_repair_RadA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041166">
        <property type="entry name" value="Rubredoxin_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18073">
        <property type="entry name" value="Rubredoxin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00416">
        <property type="entry name" value="sms"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5 6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0346">Stress response</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RECA_2" evidence="8">
        <location>
            <begin position="69"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Lon-protease-like" evidence="5">
        <location>
            <begin position="351"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="RadA KNRFG motif" evidence="5">
        <location>
            <begin position="252"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="98"/>
            <end position="105"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD88161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="452" mass="49668" checksum="9D71B406921EA2F6" modified="2019-11-13" version="1">MAKLKTTFFCQNCGAQYSKWQGQCTACKEWNTITEEVLQKPEKSDWKMPSSASKRASQPLKINDIDTSQEARLDTADQEFNRVLGGGLVPGSLTLLGGEPGIGKSTLLLQVSLKLPYKTLYVSGEESQKQVKMRAERINPSPSNCYILTETKTQNIFKQIEALEPDIVVIDSIQTLHSDYIESSSGSISQIKECTTELIKFAKETSTPVILIGHITKDGNIAGPKILEHMVDTVLQFEGDRNHVFRILRANKNRFGSTNELGIYEMQGSGLREVTNPSEVLISQKDEELSGNAIAATLEGMRPLMIEVQALVSTAVYGTPQRSATGFNAKRLNMLLAVLEKRAGFRLGAKDVFLNITGGISVDDPAIDLAVVAAILSSNEDVALKRDFCFAAEVGLSGEIRPVQRVEQRILEAEKLGFSTIFVSKYNKISLKKTAIKIHLISKVEDLVGILV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF33</accession>
    <name>A0A5C6ZF33_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Biotin synthase</fullName>
            <ecNumber evidence="3 13">2.8.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13 17" type="primary">bioB</name>
        <name evidence="17" type="ORF">ESY86_15165</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12 13">
            <text>(4R,5S)-dethiobiotin + [sulfur carrier]-SH + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2 5'-deoxyadenosine + [sulfur carrier]-H + biotin + 2 L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:22060"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="ChEBI" id="CHEBI:149473"/>
            <dbReference type="EC" id="2.8.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13 14">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="13 14">Binds 1 [2Fe-2S] cluster. The cluster is coordinated with 3 cysteines and 1 arginine.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13 14">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="13 14">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 13">Cofactor biosynthesis; biotin biosynthesis; biotin from 7,8-diaminononanoate: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the radical SAM superfamily. Biotin synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.6" evidence="3 13"/>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00078">
        <property type="reaction ID" value="UER00162"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004076">
        <property type="term" value="F:biotin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01694">
        <property type="entry name" value="BioB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010722">
        <property type="entry name" value="BATS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002684">
        <property type="entry name" value="Biotin_synth/BioAB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024177">
        <property type="entry name" value="Biotin_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22976">
        <property type="entry name" value="PTHR22976"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06968">
        <property type="entry name" value="BATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001619">
        <property type="entry name" value="Biotin_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00272">
        <property type="entry name" value="biotin_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00876">
        <property type="entry name" value="BATS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00433">
        <property type="entry name" value="bioB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13 14" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="4 13 14" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9 13" id="KW-0093">Biotin biosynthesis</keyword>
    <keyword evidence="10 13 14" id="KW-0408">Iron</keyword>
    <keyword evidence="11 13 14" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13 14" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 13 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Radical SAM core" evidence="16">
        <location>
            <begin position="39"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="329"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="15">
        <location>
            <begin position="341"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="262"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR001619-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="TXD87812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="364" mass="40570" checksum="5E0625090A676176" modified="2019-11-13" version="1">MSETKHNWTKDEILEIYNTPLMELLYQAASIHREHHDPNTVQVSTLLSIKTGGCPEDCGYCPQAARYHTNVEGNDLMTVQQVKAQALRAKSSGSSRVCMGAAWRNVKDGAEFDQVLEMVRTINKLEMEVCCTLGMITENQAHRLAEAGLYAYNHNLDSSEEYYKKVISTRGYQDRLDTIGNVRKTNVTVCSGGIIGMGENIEDRAGMLVALSTLNPQPESVPINALVAVEGTPLEEQKPISIWEMIRMVATARIVMPETQVRLSAGRTEMSREGQAMCFFAGANSIFAGDKLLTTPNPDVSEDMELFKMLGLNPQKPFIKKMQPESVEASASQYQALGEKPKWTRPEHKIERNEEAKQKGKVLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF39</accession>
    <name>A0A5C6ZF39_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">SusC/RagA family TonB-linked outer membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_15365</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023996">
        <property type="entry name" value="TonB-dep_OMP_SusC/RagA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023997">
        <property type="entry name" value="TonB-dep_OMP_SusC/RagA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04056">
        <property type="entry name" value="OMP_RagA_SusC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04057">
        <property type="entry name" value="SusC_RagA_signa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="domain" description="Plug" evidence="6">
        <location>
            <begin position="121"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="5">
        <location>
            <begin position="451"/>
            <end position="1005"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD87848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1007" mass="111513" checksum="A6BCFD175B62C229" modified="2019-11-13" version="1">MAKIGFIILLLFSVSFGFSQNQRMISGVVKSASENFPLAGATLIIKGTGKGAVTNIEGEFKYLVNSKYAIEKVVLEVSYLGFISKTVTLGKQSYFEIYLEEDISSLDEIVITSSYGTKKLKQEVVGSVASITADQLITEQPANTFDELLEGQLAGVYIETNPRLGEEISINIRGQGSLTPLNANVVGTSTQPLIIVDGIILSEEVGIDGSDFFDVGTGNLSENILNPLARVGIQDIQSFDVLKDAAAVGLYGADAANGVIIITTKSGKKGKLRVNASVQSGISEPINQFQFLNGESFQRIQNIYNTNNGDLNNVQSWNGVNTDWFSLLNRAGIFNRYGLGVSGGTEHWSYRANANYQINKESQVNNQFEKLNTTLALDYRKKDFTASLRFSPSLTVKNDPNTLYAFAIAPNIPVYDANGVYTNFETFGNPLAVAEQNISESKTFAILNSINMNYQLTDDLRLTTLFGIDYSEKDEDKLFSGLNGSGQFNDGTLGRRVQRERNTKRWNWSANLFYNKTFGKAHYFDALLGMETRQEKVDFSYALGNGFDILENAQPIASAERQNFRFDSSETTGRSVFSQLNYDFKKTYFLLANFRVDQSSAFGSDNDTALNGGFGASWIISNENFFSKNIKNPVDFLRLRVSYGSTGNSRIGSYRALGLYTVDNNDDGNGYNGNNFANASSAPNPNLGWERNNKFNIGLDVNAFNRFKITAEIFRDDIKDLIVSRSVIPESGYTNVQINGAAMYNQGVEFSLQADWLKTSKFKWQSNVNISKIENEITALKGLGSNTSSAEVARAQQIGYATSTYWGFDFIGIDPATGRELYNVDGSIYDGSYVAANFTPADWQPIGNSQPDFFGGLRNSFSYKGINLNMIFSFAYGQDALIDRVLLDNYRVLTNRNLSINVLDEAWQQQGDLASFPVISNSNRIISNSSKYLYDASHIKLKAINLSYDLPASLMKIPFEALSVFVNGSNLVYWYKHKSPKNKNGIAEFKSVYPEMRTFSLGLNASF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF43</accession>
    <name>A0A5C6ZF43_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">DNA repair protein RecO</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 7">Recombination protein O</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">recO</name>
        <name evidence="9" type="ORF">ESY86_15215</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in DNA repair and RecF pathway recombination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the RecO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00201">
        <property type="entry name" value="RecO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022572">
        <property type="entry name" value="DNA_rep/recomb_RecO_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003717">
        <property type="entry name" value="RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042242">
        <property type="entry name" value="RecO_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33991">
        <property type="entry name" value="PTHR33991"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02565">
        <property type="entry name" value="RecO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11967">
        <property type="entry name" value="RecO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="SSF57863"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00613">
        <property type="entry name" value="reco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4 7" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="5 7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_rep/recomb_RecO_N" evidence="8">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF11967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD87822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="239" mass="27912" checksum="3E37BAC2453570EE" modified="2019-11-13" version="1">MLIKTKAIVLSKIKYRDNDLIVKCYTQQKGIVSYLLRGVLKSKKGSSKSAYYQLLSQIELESSYKANQSLQYINEVKIAYVYKSLQTNILKTAIVMFLSEVLSSVLKEEEQNLELFDYIETTLQWLDLQEEFSNFHLLFLLELTKHLGFYPDTSDVNQRYFNLNNGLFQSNKLDVYSISGENLDILSQLLFVDFESLETVKLNAKQRQSFLTMLLLYYELHLGSFKKPQSLDIFNQVFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF80</accession>
    <name>A0A5C6ZF80_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Xanthine dehydrogenase family protein molybdopterin-binding subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_13240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000674">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036856">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016208">
        <property type="entry name" value="Ald_Oxase/xanthine_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008274">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037165">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11908">
        <property type="entry name" value="PTHR11908"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01315">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02738">
        <property type="entry name" value="Ald_Xan_dh_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01008">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54665">
        <property type="entry name" value="SSF54665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56003">
        <property type="entry name" value="SSF56003"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ald_Xan_dh_C" evidence="1">
        <location>
            <begin position="21"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="745" mass="81791" checksum="CCB85876C0EE1E17" modified="2019-11-13" version="1">MKISKQIGKSVNRLEGHLKVTGAAKYAGEYDVPGLLQGYIVNSTITKGKILEIDESAAHALSGVVAIFSHNNRTKLPWFDIMYADMDAPPGTPFKPFYNDQILYNGQPIALVVAETFETARYAATLIKVTYDEEPFETELAAHLDDARDPKKGIATFIKPLPPSANGDFEKAYNDADVQYAGEFIHGTEHHNPLELFTTTTVYEGDGKLTVYDKTQGTSNCQIYIANVFGLHYKDVRILSPFVGGAFGSGLRPQYQLFLCVMASLELKRNVRVTMDRAQMFTFGHRPQTIQKTRFGATADGTVTAINHTAIAETSQHEDYTEVVVNWANMLYPAKNTLLDYKLVPLDVFSPMDMRAPGGSTGLHAIEATMDALSYILKVDPMELRLLNYAERDVSANKPFSSKELKQCYLQGAEKFGWANRKSEPRTTRRGNRLVGTGMSSGIWDVIALPAKAKASINKKGKLKVKSAVTDIGTGTLTVMTQIAADSLGIHIDDVTFEYGDSNMPLSPIQGGSYTTGVVGSAVKAACESLKKKIFKKAKKMNNSTFNSVALEDVVFEDGSMHLKQDKSNFVTFKEIIADNDGKKIKASKNNIPNVLKLKQYTRAAHSAAFVEVEVDEQLGIVNVTRAVTAVAAGKIINPKTARSQILGGMIWGISKALREETLMDHNLGKYMNTDLGEYHIPVHADIHELDVIFVDEKDDIINELGSKGVGEIGLASMAPAIANAIYHATGKRVNKFPIHFDQLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFC5</accession>
    <name>A0A5C6ZFC5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">50S ribosomal protein L6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rplF</name>
        <name evidence="7" type="ORF">ESY86_14905</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 5">This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the universal ribosomal protein uL6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.930.12">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01365_B">
        <property type="entry name" value="Ribosomal_L6_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000702">
        <property type="entry name" value="Ribosomal_L6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020040">
        <property type="entry name" value="Ribosomal_L6_a/b-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036789">
        <property type="entry name" value="Ribosomal_L6_a/b-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019906">
        <property type="entry name" value="Ribosomal_L6_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002358">
        <property type="entry name" value="Ribosomal_L6_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655">
        <property type="entry name" value="PTHR11655"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655:SF14">
        <property type="entry name" value="PTHR11655:SF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00347">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002162">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00059">
        <property type="entry name" value="RIBOSOMALL6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56053">
        <property type="entry name" value="SSF56053"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03654">
        <property type="entry name" value="L6_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00525">
        <property type="entry name" value="RIBOSOMAL_L6_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 5" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L6" evidence="6">
        <location>
            <begin position="11"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L6" evidence="6">
        <location>
            <begin position="89"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD87956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="180" mass="19726" checksum="1CB0CE129D9BB4CA" modified="2019-11-13" version="1">MSRIGNNPVAIPEGVTVDIKENNITVKGKLGELTQDFDTVTIKVEDGNILVRRAGDSKEDKSKHGLYRSLMENMIEGVSNGWTKQLELVGVGYRASCQGQKLDMALGFSHNIVLNVAPEVKVETISEKGKNPVIKLTSHDKQLVGQVAAKIRGFRRPEPYKGKGIKFVGEILRRKAGKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFD6</accession>
    <name>A0A5C6ZFD6_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glycine dehydrogenase (decarboxylating)</fullName>
            <ecNumber evidence="7">1.4.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Glycine cleavage system P-protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Glycine decarboxylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Glycine dehydrogenase (aminomethyl-transferring)</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">gcvP</name>
        <name evidence="9" type="ORF">ESY86_12510</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>(R)-N(6)-lipoyl-L-lysyl-[glycine-cleavage complex H protein] + glycine + H(+) = (R)-N(6)-(S(8)-aminomethyldihydrolipoyl)-L-lysyl-[glycine-cleavage complex H protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:24304"/>
            <dbReference type="Rhea" id="RHEA-COMP:10494"/>
            <dbReference type="Rhea" id="RHEA-COMP:10495"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83143"/>
            <dbReference type="EC" id="1.4.4.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7 8">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4 7">The glycine cleavage system is composed of four proteins: P, T, L and H.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the GcvP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.4.2" evidence="7"/>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004375">
        <property type="term" value="F:glycine dehydrogenase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019464">
        <property type="term" value="P:glycine decarboxylation via glycine cleavage system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00613">
        <property type="entry name" value="GDC-P"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00711">
        <property type="entry name" value="GcvP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003437">
        <property type="entry name" value="GcvP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020581">
        <property type="entry name" value="GDC_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11773">
        <property type="entry name" value="PTHR11773"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02347">
        <property type="entry name" value="GDC-P"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00461">
        <property type="entry name" value="gcvP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7 8">
        <location>
            <position position="700"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR603437-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD88555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="950" mass="104801" checksum="4A9320E83A4ED512" modified="2019-11-13" version="1">MDTADFSLRHIGPREAQQQAMLKTIGVDSLEQLIYETVPDDIRLKKDLDLDEPMSEQDYLLHISKLSKKNKVFSTYIGLGYHPTILPAVIQRNVLENPGWYTAYTPYQAEIAQGRLEALLNFQTMITDLTGMELANASLLDESTAAAEAMGLLYAVRDREQKKNKINKFFVSEAILPQTLSVLKTRANPLDIELVVGNEADFDFSENFFGAILQYPGKHGQVTNIKPFIEKANAANIKVAVSADIMSLIKLEAPGKFGADVVVGTTQRFGVPMGYGGPHAAFFATKDAYKRDLPGRIIGVTKDANGNRALRMALQTREQHIKRDKATSNICTAQVLLAVMASMYAVYHGPDGLRHIANKIHNKTAALSKALSKLGYEQSNTSFFDTLQLKANAKAIKVAAESKKVNFYYPSEDTVVLSLNETTNLKDLNRIISIFAGVAQKDSFKISEVSEANAIDQNLQRQTDFLTGPVFNTYHSETQLMRYIKRLERKDLALNHSMIPLGSCTMKLNAAAEMLPLSWFQWGSIHPYVPVEQAKGYHKVLRKLEDQLTEITGFAGTSLQPNSGAQGEFAGLMVIKAYHESRDDHHRNICIIPSSAHGTNPASAVMAGMKVVVTKSSDDGNIDVEDLREKAEMHKDNLSALMITYPSTHGVYESAIKEITQIIHDNGGQVYMDGANMNAQVGLTNPGNIGADVCHLNLHKTFAIPHGGGGPGVGPICVAKQLVPFLPSNPLIKTGGDNAITAISAAPFGSSLVCLISYGYIKMLGARGLKRSTEVAILNANYIKKRLQGAFETLYSGERGRAAHEMIIDCRPFKAHGIEVVDIAKRLMDYGFHSPTVSFPVAGTMMIEPTESEDQAEMDRFCDAMISIKKEIETLSKEDDNNKLKNAPHTLDMITSDDWQLPYSRQEAAFPLEFVKENKFWPSVRRVDDAYGDRNLVCTCAPIEAYMEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFH5</accession>
    <name>A0A5C6ZFH5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">T9SS type A sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Por_Secre_tail" evidence="1">
        <location>
            <begin position="308"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="380" mass="43729" checksum="3DB1F4B762857796" modified="2019-11-13" version="1">MKQILLLSFSCFVFFVPSKGLSQTVYKVDEKKIFSWDSNVPDWEQEIIESYAYANGGIKETTILGLLFPGLETVYRFNKVYNSNNDIVTNTNQFWNESTNQWFDTEISTYAYDGSNNLTSRTRQAYDYVTMALVNSTREIITYSGTNIQTQTFQVWNSSTATWENDELLELFYTSGLATSGVYSIWDSNNAAWEQDEQITVTYNLNDLPEMVLTETYDGSNWSNAELSLFTYSGLLETELLNQFWSGSDWVNQERALSTYDANNNRSVYIFEDWDANLDNWEPSYKEEVSYSEATLSLANQNLFKTRLFPNPVKDVLNIEFSSGFSTETNVSLYALDGRLIFSKTIDPLEIKSNLNLEFLAQGTYILKMGNLKTQRIIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFK5</accession>
    <name>A0A5C6ZFK5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Ribose-5-phosphate isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_12685</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="116" mass="13745" checksum="304795DBD76DFDAB" modified="2019-11-13" version="1">MPKAQYRIYVVELSKKVFTENRKFREANPQFNGVLQCLYVGMTSKTAKERFLQHKTGYRNKKGHKLSANIVEKYGTYLRPSLYNHIDPLDTRLEALQMEEALALSLRRQRYAVWFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFQ4</accession>
    <name>A0A5C6ZFQ4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Epoxyqueuosine reductase</fullName>
            <ecNumber evidence="7">1.17.99.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Queuosine biosynthesis protein QueG</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">queG</name>
        <name evidence="9" type="ORF">ESY86_14400</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>AH2 + epoxyqueuosine(34) in tRNA = A + H2O + queuosine(34) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:32159"/>
            <dbReference type="Rhea" id="RHEA-COMP:10345"/>
            <dbReference type="Rhea" id="RHEA-COMP:10346"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:82831"/>
            <dbReference type="ChEBI" id="CHEBI:82834"/>
            <dbReference type="EC" id="1.17.99.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="7">Binds 2 [4Fe-4S] clusters per monomer.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>cob(II)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="7">tRNA modification; tRNA-queuosine biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the QueG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.17.99.6" evidence="7"/>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00392"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052693">
        <property type="term" value="F:epoxyqueuosine reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00916">
        <property type="entry name" value="QueG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004453">
        <property type="entry name" value="QueG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013542">
        <property type="entry name" value="QueG_DUF1730"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30002">
        <property type="entry name" value="PTHR30002"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08331">
        <property type="entry name" value="DUF1730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00276">
        <property type="entry name" value="TIGR00276"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7" id="KW-0846">Cobalamin</keyword>
    <keyword evidence="7" id="KW-0170">Cobalt</keyword>
    <keyword evidence="1 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0408">Iron</keyword>
    <keyword evidence="6 7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 7" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="8">
        <location>
            <begin position="174"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Cob(II)alamin binding" evidence="7">
        <location>
            <begin position="239"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="132"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>cob(II)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>cob(II)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>cob(II)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>cob(II)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>cob(II)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>tRNA</name>
            <dbReference type="ChEBI" id="CHEBI:17843"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD88075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="308" mass="35355" checksum="C65726806908B771" modified="2019-11-13" version="1">MKDSKSKYSQFIKAEAKRLGFLSCGISKAEFLEEEAPRLERWLKNNAHGEMQYMENHFDKRLDPTKLVEGSKSVVSLLLNYFPEDTQTENTFKVSKYAYGTDYHFVIKDKLKTLLQSIQTEIGEVGGRAFVDSAPVLDKAWAAKSGLGWIGKHSNLLTQQVGSFYFIAELIIDLELEYDHAVTDHCGTCTKCIDACPTQAITEPYVVDGSKCISYFTIELKENIPTEFKGQFEDWMFGCDICQDVCPWNRFSKAHSEPLFNPHPDLLSMTKKDWEEITKDTFNKVFQKSAVKRTKFEGLKRNVEFLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFZ2</accession>
    <name>A0A5C6ZFZ2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_15865</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="146" mass="17391" checksum="19E19AD3B064EC01" modified="2019-11-13" version="1">MALKMTQIENLLVNNKSKSTFFELIIAYSRLKHKIEDTENHSWYFKKGLESKMEEMASLNNHFEKMREVFHESTIDSFTDKINENNLYLAASEGKYKGFNKRVVCSWKISENRYFNELMSLKGKTELLMPIDYYSDNPEEFFKLID</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFZ5</accession>
    <name>A0A5C6ZFZ5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Phosphatidylcholine 1-acylhydrolase</fullName>
            <ecNumber evidence="8">3.1.1.32</ecNumber>
            <ecNumber evidence="9">3.1.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">ESY86_10860</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 1-acyl-sn-glycero-3-phosphocholine + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15801"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
            <dbReference type="ChEBI" id="CHEBI:57643"/>
            <dbReference type="ChEBI" id="CHEBI:58168"/>
            <dbReference type="EC" id="3.1.1.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 1,2-diacyl-sn-glycero-3-phosphocholine + H2O = a 2-acyl-sn-glycero-3-phosphocholine + a fatty acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18689"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28868"/>
            <dbReference type="ChEBI" id="CHEBI:57643"/>
            <dbReference type="ChEBI" id="CHEBI:57875"/>
            <dbReference type="EC" id="3.1.1.32"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer; dimerization is reversible, and the dimeric form is the active one.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell outer membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the phospholipase A1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.32" evidence="8"/>
    <dbReference type="EC" id="3.1.1.4" evidence="9"/>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052740">
        <property type="term" value="F:1-acyl-2-lysophosphatidylserine acylhydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052739">
        <property type="term" value="F:phosphatidylserine 1-acylhydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008970">
        <property type="term" value="F:phospholipase A1 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004623">
        <property type="term" value="F:phospholipase A2 activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003187">
        <property type="entry name" value="PLipase_A1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036541">
        <property type="entry name" value="PLipase_A1_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40457">
        <property type="entry name" value="PTHR40457"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02253">
        <property type="entry name" value="PLA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01486">
        <property type="entry name" value="PHPHLIPASEA1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56931">
        <property type="entry name" value="SSF56931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="16" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="15 18" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <keyword evidence="11 18" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1134">Transmembrane beta strand</keyword>
    <keyword evidence="18" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="18">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00010525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00011702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00013179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00013278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00032375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="TXD88983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="290" mass="33962" checksum="999FC2E3B1E1D068" modified="2019-11-13" version="1">MIQFAKDFQTKYTLNNLALKALASFWMLFVFMSTNAQQDISKDSTVVINVIKTMPSFSIHNDNYFITGTTIGETPDANNSDGKLKIGFKQRLTNKTLPFDTYLFFTYQQTAFWDIYKKSLPFRETNYNPSLALVKPLYRNKEFNGFLQFQFEHESNGRDADSSRSWNRLSLIYRRYLSDDFTGTLKVWLPVGSKTGNADITDYRGFQQLDLAYKLDEDFIFEAEMRKAFSWDAIGSLLLGANYRISQASEQFIYLQYFLGYSEDLITYDQHVHRIRIGIVFKDLFLKFRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG91</accession>
    <name>A0A5C6ZG91_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribosome-binding ATPase YchF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 7" type="primary">ychF</name>
        <name evidence="7" type="ORF">ESY86_11870</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. YchF/OLA1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04867">
        <property type="entry name" value="TGS_YchF_OLA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01900">
        <property type="entry name" value="YchF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00944">
        <property type="entry name" value="YchF_OLA1_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004396">
        <property type="entry name" value="ATPase_YchF/OLA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023192">
        <property type="entry name" value="TGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013029">
        <property type="entry name" value="YchF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041706">
        <property type="entry name" value="YchF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06071">
        <property type="entry name" value="YchF-GTPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006641">
        <property type="entry name" value="CHP00092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="SSF81271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00092">
        <property type="entry name" value="TIGR00092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OBG-type G" evidence="5">
        <location>
            <begin position="1"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="6">
        <location>
            <begin position="279"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="10"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD88657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="364" mass="39952" checksum="F2B5C2940D26D42D" modified="2019-11-13" version="1">MKAGIVGLPNVGKSTLFNCLSNAKAQSANFPFCTIEPNIGVVNVPDSRLEKLESLVNPERVLPATVEIVDIAGLVKGASKGEGLGNQFLANIRETDAILHVLRCFDDDNIIHVDGNINPIRDKETIDMELQLKDLETVDKKLDKVKRAAKTGNKEAQKEEAVLLKIKSGLEAGISVRALEFSDDDYADFVKPAQFITDKPVMYVCNVDEASATTGNAYVEKVREAVKDENAEVLVLAVGTEADINELDDYEERQMFLQDIGLKEAGSAKLIRSAYKLLNQQTYFTAGVKEVRAWTIDVGATAPQSAGVIHTDFEKGFIRAEVIAYEDYVAFGSEAKVKEAGKMRVEGKNYVVKDGDVMHFLFNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGD4</accession>
    <name>A0A5C6ZGD4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Prohibitin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_13235</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03401">
        <property type="entry name" value="SPFH_prohibitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000163">
        <property type="entry name" value="Prohibitin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23222">
        <property type="entry name" value="PTHR23222"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00679">
        <property type="entry name" value="PROHIBITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022908900" evidence="1">
        <location>
            <begin position="22"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="PHB" evidence="2">
        <location>
            <begin position="16"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="259" mass="28845" checksum="F539EFE8EA013AB7" modified="2019-11-13" version="1">MKTKFLLLTAILLLFSNCAVIRPGEAGVKQTLGKFSDDVITEGTVIYNPFISKIIKESTQTNNIKLVLSLPSKEGLSVDSEISILYRLEQNKIPSVLENLGQEYEDIITSVFRSASSDVCAKFYAKDMHSGMRSTIEEEIKIKMEENLLKQAEGIELIAVLMKSIRLPRGLANSIEEKLQAEQDAMRMEFVIQQAKLEAERKIIDAEGERDAQIILATGLTPEIIKIKSIDAFNRLSASPNSKIIITDGKTPMLINPNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGG1</accession>
    <name>A0A5C6ZGG1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sigma-70 family RNA polymerase sigma factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_13420</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="26"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="3">
        <location>
            <begin position="126"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="189" mass="22107" checksum="A4231987B5D7BF2C" modified="2019-11-13" version="1">MKQNQHKSVQLWAKLQQGDLDALGKLYDAFSDDLFTYGMQFTPDKAVVMDGIHDVFLNLYKYRKNLAKTDAVDYYLMRSLKNTILKKCQSQLREVPSEIPQTLAHCQASVEQGLIENEIKNERSYKLTRAMSSLSKKQRKSLFLRFTENHSYEEIAEIMQISVASSRTTIYRAIKSLRKQMHLFFTFFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGY0</accession>
    <name>A0A5C6ZGY0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08375</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="125" mass="14618" checksum="F99D0C895FD18B78" modified="2019-11-13" version="1">MTFFDQLFFSCFKHYKPKYKQKANTIALFYISSLQCALLLLTGLLLAFFLKQMHTTSMSSDNAWLLFVLGCFIIIFKNWIQYSGKKRKIMNAKNLNNKEQLYSVWILWILLVGTILFSAILLQGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH32</accession>
    <name>A0A5C6ZH32_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L29</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpmC</name>
        <name evidence="6" type="ORF">ESY86_14870</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL29 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00374">
        <property type="entry name" value="Ribosomal_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001854">
        <property type="entry name" value="Ribosomal_L29/L35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036049">
        <property type="entry name" value="Ribosomal_L29/L35_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018254">
        <property type="entry name" value="Ribosomal_L29_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00831">
        <property type="entry name" value="Ribosomal_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46561">
        <property type="entry name" value="SSF46561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00012">
        <property type="entry name" value="L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00579">
        <property type="entry name" value="RIBOSOMAL_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD87949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="63" mass="7146" checksum="F55D6772FFC78413" modified="2019-11-13" version="1">MKQAEIKKLSVADLNDKLGETKKSYADLKMAHAVSPLENPIQLRNVRRTVARIATELTKREVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH34</accession>
    <name>A0A5C6ZH34_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RHS repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_09600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023082273" evidence="1">
        <location>
            <begin position="20"/>
            <end position="1303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1303" mass="146187" checksum="0619262916966482" modified="2019-11-13" version="1">MKYTIFIPVFLIISYCVSAQEIRNNDPFYLSENIASSPEASSLGRYGNIKASPYNGKANVSLPLYSIDFEGLKIPIQLNYDTGGVRVVQEASWVGLNWNLSTTHGISRKVYGIDDFSKRNANLYNTYNGYIYNPLVMGLLEGADRPYLDIDDILNVHESYGNTSVAGDGSSYLDTQPDVFNVSVLGQSYTFILEKKGTGDILQTKVFNSNNVKIIFDLLTMSFDLIDENGFKFHFETNEVNTNFSTVSENTPPTDYLESIALIFSRTHRANESIITTWLLDNVTSPRGRVLNFNYQKGLHFTFPDYSFDYNIRGNEALNGWPNEQYNSVSGQNTLIGHKANYNVSFTVIENNYLTSITGNFGSVEFHLENRLDLSTGSTINLLSQNNFGTKVLTTSQSGSIRSCHGTTTNCGTNTPYLPWKLSGFSVKNNSGKNVFNVDFGQSYFNSNEINSPIKERYLRLKLDTVTINDQIHSFEYSDVNLLPAKDSYAVDFWGFSNGKINNNTYNPSLGRFITKYINTPSGSTSAQSFMNFKGADRSSDFLYGKRGLLNKIVYPTKGSTVFEYEAHDVVLDTPPLFQVTQYVPNSQRMRWTDMTDESKFDITFQYLKCSKDSNYNYFEREGTLEQGSPIIIPVVINEVFEVSFPSLIQISGSINTYTGWNGIGYWGNRPILVVEEINNGQEYVVFTYGDAPSNQGSPPNNVSKSISIPPGEFRIVRRWATLPAGEDYNNYPPIPASYFQPNSLLVKTYENINNISAFFERFEVGGARIKKIINKDANALFASGKEYKYNYTGAIAGLSSSGVLMDDLIYHNSGAGLHSFNPSGYNFSFKGYNMVGGNTSAQGSHIGYSFVQEFPINNLNNQLGHVDRTYHNLKNKYFKDSFCFPFMYDGITNDNYGTIHIFGFDTGWSCFGGGGMFDCDDGTGGKVYSRTGDACVENTVVLGLPTRLDYSYINGSIIKESTYNQNQNLLKKTENSYALLKGDVPLDYFTSFMNIGIHGIIGQNGGVAATLLNTTQGPWGADHHTYFPYLFPLHHGLVSKLSNSIKTEFMNSGDVVSESILIYNNITHLPTISTSLLNETEEVSNRLFYPNDSEVYGKPFMSNLRAENRLATVIKANSYKENNKLSTLEYSYAKNVNTANITLVTSISKSKGEATLKEDVIYEKYDNKGNLLQYRQKDGTPIIYIWGYNEQYPIVKIENAVYAQVSGQVINIQNKSNLDDDNCTDAENCDEKNLRTALNSLRLSLPLAMVTTYTYDPLVGLTSMTDPKGYTVYYDYDAFNRLRQAKDADGKILSETEYHYRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH61</accession>
    <name>A0A5C6ZH61_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ferredoxin--NADP reductase</fullName>
            <shortName evidence="2">FNR</shortName>
            <shortName evidence="2">Fd-NADP(+) reductase</shortName>
            <ecNumber evidence="2">1.18.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_14040</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H(+) + NADP(+) + 2 reduced [2Fe-2S]-[ferredoxin] = NADPH + 2 oxidized [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:20125"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.18.1.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="2">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ferredoxin--NADP reductase type 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.18.1.2" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004324">
        <property type="term" value="F:ferredoxin-NADP+ reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01685">
        <property type="entry name" value="FENR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022890">
        <property type="entry name" value="Fd--NADP_Rdtase_type_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="1 2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="3">
        <location>
            <begin position="5"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="289"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="330"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="353" mass="38582" checksum="32645CDC44C8877B" modified="2019-11-13" version="1">MIKTDILIIGAGPTGLFAVFEAGLLKLKCHLIDALPQAGGQCSEIYPKKPIYDIPAYPEILAGDLTDKLMEQCKQFKPGFTMGERAETIEKQEDGSFIVTTNKGTKHQAPVVAIAGGLGSFEPRKPLIPNIASFEDKGVEYFIKDPEVYRDKRVVIAGGGDSALDWSIFLSAIAKSVTLVHRRNEFRGALDSVEKVQELKNQGKITLITPAEVTNVVGHHKVEAVVIAQAKNIEKEFEVECDHFIPLFGLSPKLGPIANWGLEIEKNAIKVNNSLDYQTNIPGIFAIGDVNIYPGKLKLILCGFHEATLMCQAAYQIINPGKRYVLKYTTVSGVDGFDGTRKESPKAVVKAID</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHB0</accession>
    <name>A0A5C6ZHB0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11860</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="159" mass="18539" checksum="CFB0AE422F8FE1EB" modified="2019-11-13" version="1">MRTNNSNVKNTIVSVYFILVVLAIVMATLSRVFSDITSDSAIAMVLVLVGFTLIFFLVHRVSKYFEYDSDGLNVIILNKGLMLSDNFNYREKRIEFAKDNLLAFKFNNFLFYRTLVIYTSNSRGKKSKDTFNVTLLTKKKRRYIRQSLTKIIKLKHKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHF5</accession>
    <name>A0A5C6ZHF5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_07335</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039426">
        <property type="entry name" value="BtuB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30069">
        <property type="entry name" value="PTHR30069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023124414" evidence="5">
        <location>
            <begin position="18"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="7">
        <location>
            <begin position="118"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="6">
        <location>
            <begin position="319"/>
            <end position="765"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD89592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="768" mass="84765" checksum="2D5F4E274C85306A" modified="2019-11-13" version="1">MRNFTIICLFLGASASAQNGTAKVSGQVTAEGLAVPFASVYVKGGTNGTNTDENGRYQLELSVGKVTLVAQSQGYKTLSKTLSISANEGQIVDFVLEESNAVLDEIVVTGTRTEKRRTDSPVIVNLINSETLEQVVATDLSEGLRFQPGLRVEMNCQTCNYSQIRMNGLQGGYSQILINGRPIFSPLTGLYGLEQIPVNMIERIEVVRGGVSALYGSSAIGGTVNVITKIPKQNGYSFSYAYQNINGGADQSLINGNATVVSKDYKSGANFFVNTRTRTAYDANGDNFSELPELKDNSFGINAFYLPTENSKLEVSFSSLYEYRFGGEIVEKPAYLTQQSEERDHHVLMGSLDYQINFNEDKSALILYYGGQRTDRDHYTGIIPDDETEKNAFFADPPYGVSDVITHQGGLQYNHKLDAFLGGTTVLTAGAEYLYDDVFDEITAYDYEIDQTTRNLGVFFQNDWEVTESFNFLAGFRVDKHNLVDHAIVSPRVSLLYKLEETTQFRLGWGTGFRAPQAFDTDLHIAFAGGGVSRISLAENLEEERSNSFTASVNYDKATEHFIAGFTLEGFYTHLNDAFYQFPLGEDAFGERFEKRNGSGATVKGITLEARANFDYVVELAAGFTLQSSLYDDAVENIEGLELKREFLRTPNDYGYATLTYTPTKKLTASANLIYTGKMDIIHFAGEGTGQDVDEYDVTPTFTELSLRVGYTFNLPKVSTNIELFGGVKNVTNSYQADFDTGKNRDSNYIYGPAAPRTVFVGLKLDSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHS5</accession>
    <name>A0A5C6ZHS5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_13065</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="69" mass="7144" checksum="908C31963B5D9891" modified="2019-11-13" version="1">MRIQNKNIIASILFVLISFVCIGQGGTTGPPPPAGPPGPPGLPIDGATTIAVIAGLFYGIKKTLKHYKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHW3</accession>
    <name>A0A5C6ZHW3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">IPExxxVDY family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_08160</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="160" mass="18749" checksum="A9E29E29BC9E3ED6" modified="2019-11-13" version="1">MAMHKLLVDDFFDDSFLLLAVHCRLEDYRLAFLLNKYLELRLARRAQDLDYNYFAASYAIYEWEDSKFDTIWNLVANSCKRQENSIQSSGSLFDNQNVVTKINYLVPELKKADFLIKVSNENQQLDEKKILNSIQAIPQIITAYSADLNNIRSKEHLIFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHX1</accession>
    <name>A0A5C6ZHX1_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L27</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpmA</name>
        <name evidence="6" type="ORF">ESY86_08215</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the bacterial ribosomal protein bL27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00539">
        <property type="entry name" value="Ribosomal_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001684">
        <property type="entry name" value="Ribosomal_L27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018261">
        <property type="entry name" value="Ribosomal_L27_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15893">
        <property type="entry name" value="PTHR15893"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01016">
        <property type="entry name" value="Ribosomal_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00063">
        <property type="entry name" value="RIBOSOMALL27"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00062">
        <property type="entry name" value="L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00831">
        <property type="entry name" value="RIBOSOMAL_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD89366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="86" mass="9166" checksum="C3283BF8355AAC7B" modified="2019-11-13" version="1">MAHKKGVGSSKNGRESESKRLGVKIFGGQAAVAGNIIVRQRGNTHHPGENVYGGKDHTLHAQVDGLVKFARKKGGKSFVSIEPFEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI03</accession>
    <name>A0A5C6ZI03_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="1">
        <location>
            <begin position="26"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="217" mass="24631" checksum="AC1C8B63037569FB" modified="2019-11-13" version="1">MTSDTQISNTIAFVKKELYNAEGGHDWFHIERVYKNAMLIAKTETVDHLTVALGALLHDIADSKFHDGDETVGPRKAREFLFEQNVDSKVIEHVVQIIENISFKGGNFQQNFASAELDVVQDADRLDALGAIGIARTFNYGGFKNRKIFDPDIKPSLNMTKAEYKGSTAPTINHFYEKLLLLKNQMHTSTGRKLAAGRHDFMEQFLEQFYDEWDGLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI04</accession>
    <name>A0A5C6ZI04_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_06260</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="174" mass="19092" checksum="36874C2C2D936D91" modified="2019-11-13" version="1">MKNFGLLILGIIIGAIAMYFYVQQNSSDLEGVDPTEPKGLITAEEAKTLDRAYDPRYKLISDSIVTREGGDNRSSWYALEEVRTFLDYAEDQAKKNNYTMNGIRIYLGAYPESNEGQGYTTMFMMPTGYSANQNKSEGNLLGLSLKRGDDGDIPGVGGLNHGSEGKPPGANYPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI11</accession>
    <name>A0A5C6ZI11_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="6">2.3.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ESY86_12595</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>(R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + acetyl-CoA = (R)-N(6)-(S(8)-acetyldihydrolipoyl)-L-lysyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:17017"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:10478"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="ChEBI" id="CHEBI:83111"/>
            <dbReference type="EC" id="2.3.1.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
        <text evidence="6">Binds 2 lipoyl cofactors covalently.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Forms a 24-polypeptide structural core with octahedral symmetry.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.12" evidence="6"/>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043231">
        <property type="term" value="C:intracellular membrane-bounded organelle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045254">
        <property type="term" value="C:pyruvate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004742">
        <property type="term" value="F:dihydrolipoyllysine-residue acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006086">
        <property type="term" value="P:acetyl-CoA biosynthetic process from pyruvate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045257">
        <property type="entry name" value="E2/Pdx1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006257">
        <property type="entry name" value="LAT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23151">
        <property type="entry name" value="PTHR23151"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="SSF47005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01349">
        <property type="entry name" value="PDHac_trf_mito"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4 6" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="10" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="8">
        <location>
            <begin position="2"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="8">
        <location>
            <begin position="171"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="9">
        <location>
            <begin position="331"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="79"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="263"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="85"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="263"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="313"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD88572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="611" mass="66949" checksum="7586FA85DE618AC8" modified="2019-11-13" version="1">MAEIINMPRLSDTMEEGTVASWLKKVGDKIEEGDILAEIETDKATMEFESFYEGTLLYIGVQEGETTKVDELLAIIGEEDEDISEYTNGSSKAKSEDKSDDDSDEDKEDKKKASDEDEDTSEEKNSEEKSEKAAKKDKAEASEDEDEDEAKDEAEDETSNEDASGDLPEGVTVVTMPRLSDTMEEGTVATWLKKKGDQVEEGDMLAEIETDKATMEFESFQEGTLLHIGLDEGETAKVDALLAIIGPEGTDVSNIIKNFKAGGDASAKEEKPKKESKEDSKKEEKKDDKKEEQKTDKKEEAPKQDTKKEEKPSSSSSTSSSSSSSDSSRVFVSPLAKKMAEEQNINLSQLKGSGENGRIVKRDIENYTPQAASAAASGEFVATGQEDYEEKNNSQMRKAIAKALTNSKFSAPHYYLNVEYDMENAIAFRAQFNSVPDVKISYNDMIVKACALALKKHPQVNSQWFADKMRLNHHVHIGVAVAVEDGLVVPVVKFANEQTLPQIGAAVKDYAGRARNKKLTPQEMEGSTFTVSNLGMFGIESFTSIINQPNSAILSVGAIVEKPVVKNGQVVVGNTMKLCLACDHRTVDGATGALFLETLKGYIENPITMLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI68</accession>
    <name>A0A5C6ZI68_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_08895</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039426">
        <property type="entry name" value="BtuB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30069">
        <property type="entry name" value="PTHR30069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022922115" evidence="5">
        <location>
            <begin position="22"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="7">
        <location>
            <begin position="48"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="6">
        <location>
            <begin position="219"/>
            <end position="701"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD89486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="703" mass="79330" checksum="4778B9644A451003" modified="2019-11-13" version="1">MKYKCLIINTLTILSFLNVVSQEVVGSTQVNKLEEVILTATRTERQLSSLPLPVTLISKKKILQSGTIRLDEILSEQTGIITVADESGFEGVQIQGIASDYILILIDGVPLVGRSAGNFDLSRITIGNIKQIEVVKGPSSSLYGSEALGGVINIITEKPKSEELNGNVSYRIGSFTQQDINLDIKQRYKKLRYGFFANRFSSEGYDLNPDVEGQTVNPFENYTVNGRVYYDFNDKLALFTSTRFYDQIQDAGFTFNDVQFEGDSKEREWNAHARLDQKWNEKLTTSYEFYYTNYTANERLADPISDDVLSDSDFDQKLVRPEIRGSYAFAPADRSGNAGWKAGTLTAGLGFQYDELDRTFFDEPVSFNSQYVYAQYDINPIERLNVIAGARFDNHSEYSNQFSPKLAMRYKLTDAFAVKGSVGYGFKAPDFRQLYFDFTNSAVGYTVLGYNVALEKLQELQEQGQILDVVVSDDDLNNPLEAESSVGYNLGLTFKEGKWNSELNFFRNDIKNLIDTRIIARKTNGQNVFSYVNFDEIYTTGFEINTGYKINDAINLSAGYQLLYAYDKKKQQDVEDGQVFARDPATNQTVAVTQSDYFGLVNRSRHNANFKVFYDIASAKANINLRLLYRSKYAQFDTNGNGLIDSYDTSFIDGFLTANVAASKTFYEDFTLQVGANNLLDYTDNNIPTLPGIQGYVKLNYQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIA3</accession>
    <name>A0A5C6ZIA3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Gliding motility lipoprotein GldD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">gldD</name>
        <name evidence="1" type="ORF">ESY86_08640</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019850">
        <property type="entry name" value="Motility-assoc_lipoprot_GldD"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03512">
        <property type="entry name" value="GldD_lipo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="193" mass="21727" checksum="79C478EA50C1659C" modified="2019-11-13" version="1">MTIKKFIIPILASVCISCGSDPLPKPKAMLRLEYPQPKYVKVDVPLPFTFEKNVLADDISSIKLDGVNNLVGVDVTYPSLKGTVYLTYKKVEDGNLTKLLTDAQELTQKHSIKADEIEGVLYENPNNKVFGMFYEVGGNAASQSQFYVTDSTNHFLTGSLYFYAKPNYDSILPAAEYLKKDIKHIMETIEWKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIN5</accession>
    <name>A0A5C6ZIN5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TGc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_04765</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002931">
        <property type="entry name" value="Transglutaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01841">
        <property type="entry name" value="Transglut_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00460">
        <property type="entry name" value="TGc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022694624" description="TGc domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="TGc" evidence="2">
        <location>
            <begin position="117"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="338" mass="38839" checksum="444E16B44EF11FFA" modified="2019-11-13" version="1">MFLKKSLLFSILILVLGQSYAQISDFESINFTRADNRAVLHEGRSLENLPVLAHDLTFNLDTEVEKFRAIYRWVCHNISGDIRQNNITSRKREKYRNDSIAYLKWNAEYKRIAFKTLLRRKKTMCTGYAYLIKELCFLANIEAVIVDGYGRTVASNVEALDMTNHSWNAVKLNDKWYLCDATWSSGYMVNDALFINDYNAGYFLAEPKLFAKNHYPIQKKWLLNAILSASEFVESPLIYGATFEHQIIPVSPTRLTTNTGTDTEVHFSFKTLEQVDGESIQLIQSSGSREKAFKIEGFKNENGTVRFTTKFRHKGTYDVHLKIGSDVVASYTIRVDKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIP0</accession>
    <name>A0A5C6ZIP0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF3800 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_07410</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024524">
        <property type="entry name" value="DUF3800"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12686">
        <property type="entry name" value="DUF3800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="230" mass="27195" checksum="4DD53521525469DB" modified="2019-11-13" version="1">MKFEVYCDESSPEVLWDRTANKYLVLGSVWIPSDFREELKEAIKQIKNKHNYRNEIKWNKVSPSSFNFYKALVHYFFSTDSIRFRAIIVEADKVDMVKFHNDDSELSFYKFYYQLLHHWILDFNEYYIFIDHKINKDLNRIHNLKDVLNQANLFSSIENVQALPSHELLGIQMADFLMGAINGKMNGKITSETKKEIINEIEKRLGHAIMATPKAEEKFNIFKINLQGGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIT6</accession>
    <name>A0A5C6ZIT6_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">Adenine DNA glycosylase</fullName>
            <ecNumber evidence="3 12">3.2.2.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">mutY</name>
        <name evidence="14" type="ORF">ESY86_08655</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Adenine glycosylase active on G-A mispairs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>Hydrolyzes free adenine bases from 7,8-dihydro-8-oxoguanine:adenine mismatched double-stranded DNA, leaving an apurinic site.</text>
            <dbReference type="EC" id="3.2.2.31"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="12">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the Nth/MutY family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.31" evidence="3 12"/>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000701">
        <property type="term" value="F:purine-specific mismatch base pair DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03431">
        <property type="entry name" value="DNA_Glycosylase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005760">
        <property type="entry name" value="A/G_AdeGlyc_MutY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000445">
        <property type="entry name" value="HhH_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044298">
        <property type="entry name" value="MIG/MutY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029119">
        <property type="entry name" value="MutY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42944">
        <property type="entry name" value="PTHR42944"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00633">
        <property type="entry name" value="HHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14815">
        <property type="entry name" value="NUDIX_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="SSF48150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01084">
        <property type="entry name" value="mutY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6 12" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="11 12" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 12" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENDO3c" evidence="13">
        <location>
            <begin position="35"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU365096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TXD89442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="348" mass="40246" checksum="6547DA4D4E8C7A0B" modified="2019-11-13" version="1">MHFKTRLTNWYSIHKRSLPWRQTKNPYYIWLSEIIMQQTQVKQGSPYYEAFVSRFPTVFDLADAHEEEVLKLWQGLGYYSRARNLHASAKHIASNLNGIFPKTYSEIIKLKGVGDYTASAIASICFDEPTAVVDGNVYRVLSRYFGIDTPINSTEGVKEFKKLATTLIDHEHPGDYNQALMEFGATQCKPKNPYCLHCPFNASCEALQKGRIDQLPVKLGKTKVSKKHFNFLVLISPDRTTLFEKRTKKGIWRNLYQFPLIETKTELAAEDFKQHPKIKAYFEDLPFEHSLYNTKELIHKLSHQHLHTRFWIIELEALPEQGMPISEVKNLPAPILIGNFIEAFDFTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIU8</accession>
    <name>A0A5C6ZIU8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Haloacid dehalogenase type II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HAD-like hydrolase superfamily. S-2-haloalkanoic acid dehalogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019120">
        <property type="term" value="F:hydrolase activity, acting on acid halide bonds, in C-halide compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02588">
        <property type="entry name" value="HAD_L2-DEX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006328">
        <property type="entry name" value="2-HAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01493">
        <property type="entry name" value="HAD-SF-IA-v2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01428">
        <property type="entry name" value="HAD_type_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="248" mass="27219" checksum="F824AC3095A9F276" modified="2019-11-13" version="1">MGIMGTTEPISENAQEKEDLNLTKIRPKVLFFDVNETLLDLTQVRAQVAQALEGRDDLLALWFTTMLQYSLVMTTSGQYDHFANIGAAALQMVAANNNIDITQAKARETVVNALRGLPAHPEVKAALAQLKSDGYKLVSFTNSSNEAVKKQFESAGLTDYFDERLSVEDIGKFKPSKATYDWAAHKMGVKPSEAMLVAAHGWDVAGASWAGWRAAFVSRPGQQLFPLAAKTEINEPDLQKIAAILVKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIX5</accession>
    <name>A0A5C6ZIX5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2061 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018638">
        <property type="entry name" value="DUF2061_membrane"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09834">
        <property type="entry name" value="DUF2061"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2061" evidence="1">
        <location>
            <begin position="10"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2061" evidence="1">
        <location>
            <begin position="80"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="142" mass="16347" checksum="69759C26F834BCB1" modified="2019-11-13" version="1">MNDQSHKRHIAKAVTWRLVGTIDTIILSWIISGNPLTGLKIGMAEVLTKMVLYYFHERVWFKINLSKDGEVLESRKRHFAKTVTWRVIGTIDTMTLAWIITGNPLTGLKIGAAEVVTKMILYYVHERAWYKVNYGLPSRTKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ13</accession>
    <name>A0A5C6ZJ13_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">mRNA interferase</fullName>
            <ecNumber evidence="1">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11815</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Toxic component of a type II toxin-antitoxin (TA) system.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PemK/MazF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="1"/>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003477">
        <property type="entry name" value="PemK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011067">
        <property type="entry name" value="Plasmid_toxin/cell-grow_inhib"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33988">
        <property type="entry name" value="PTHR33988"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02452">
        <property type="entry name" value="PemK_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF033490">
        <property type="entry name" value="MazF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR033490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="107" mass="12374" checksum="7B3F970A453C6D7A" modified="2019-11-13" version="1">MELKQYSIILVNLNPTIGSEIKKTRPYVIISPNEINRFLNTIVVAPMTTNLKKYPTRIAVKHKDKKGMIAIDQIRTIDKSRILKSFDRLSKSEIQKCKAIIRETFVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ16</accession>
    <name>A0A5C6ZJ16_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF4886 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_08970</name>
        <name evidence="2" type="ORF">ESY86_20710</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000107">
        <property type="protein sequence ID" value="TXD85945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD85945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="96" mass="10772" checksum="34773E7CD4C4C7F2" modified="2019-11-13" version="1" fragment="single">MKNLLLILITLTTISCKSQNTETTDEINVLFIGNSLTYFHEMPQTVQKMLNETNPNIKIEQSTFPGQSLSGHLSDIITSRTENGISTRKKEDGEKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ29</accession>
    <name>A0A5C6ZJ29_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022712961" evidence="1">
        <location>
            <begin position="19"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="233" mass="26035" checksum="B06D09AB8E44DB9C" modified="2019-11-13" version="1">MKKILLTVIMLTTLGVTAQNNDQLKKHFEAYYLQMKGQGDVQGVINALTHLNVIAPNQARLDTLAYVYVSEGRNLEALNTIGIEKGPNDADINVEVKAIALKAMNQPERALTFYNELFKRDSNPYIAYEIADLLTINQDFAGAKAQVEYGLINATDDMKRAFYESQRPYEVPLKAAFTYMKALVVFNMNKADNLDQAIGLLDEALVMAPNFNIAKLSKDALEARKVTPPKDKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ67</accession>
    <name>A0A5C6ZJ67_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_04955</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005144">
        <property type="entry name" value="ATP-cone_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007560">
        <property type="entry name" value="Restrct_endonuc_IV_Mrr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03477">
        <property type="entry name" value="ATP-cone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04471">
        <property type="entry name" value="Mrr_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51161">
        <property type="entry name" value="ATP_CONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-cone" evidence="4">
        <location>
            <begin position="5"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="278" mass="31935" checksum="FA44B4943370F088" modified="2019-11-13" version="1">MDTNFNVIKSSGEKVKFSLDRLRASLRKSGADGQTITQIVDKVQGELYDGISTKEIYNRAFALLKKKDSYLASKYKLKKAIYELGPTGYPFERFVSAILKYSGYETRVSEIMQGHCVTHEIDVIAHKNGHTTVIECKFHSEEGRNCNVKVPLYIASRFKDVKSHWDSKAHDTKLEAGWVVTNTRFTEDARQFGKCIGLYLLSWDYPKNDGLRDRIDRLSLYPITASTLLTNREKQFLLSRDVVLCRDLKDDVFFLDHLGISETRKSKIINEIKMLCKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJL4</accession>
    <name>A0A5C6ZJL4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03285</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="49"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="243" mass="28458" checksum="B9C9C21DF1EC5D11" modified="2019-11-13" version="1">MIPHTQQWFDSWFDSPFYHILYEDRDHSEAQQFMDNLSNYLNLPENGTVLDLACGKGRHSIYLNSLGYDVTGVDLSENSIAYAKQFENESLHFEVHDMCKPFNKQFDAVFNLFTSFGYFEKDNENLDTIKAIQAELNEYGFGVIDFMNSTQVIENLVDEDIKTVHGIDFHQKRYVKDGHIIKDISFSAEGEHYEFQERVRAFTLADFEQLFEKAGVHLLDVFGDYKLNKFHKHSSERLVMIFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJN4</accession>
    <name>A0A5C6ZJN4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_03845</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="157" mass="17686" checksum="7AD7F1472FC862E1" modified="2019-11-13" version="1">MLIYLDIDGVMVPANSWRQLKILEDGFPEFSSRATQALNKIIAKTGADIVLTTSHKTLFSLEQWAAIFNHRHIQVNNISRLPDNVSLLNRKDELLKWFESQDTNQGFIIIDDDKSLNALPDVLKNKLIQTSASVGLTDYLANEALEILSKFDIGQDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJW3</accession>
    <name>A0A5C6ZJW3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_04260</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="235" mass="27317" checksum="02C906FB1E6BE655" modified="2019-11-13" version="1">MKKIYIVLISMVLFSCGNEKKILLPEIENAKITEVLDVSPAYLFYDETKADSVELNRKNLISTTNWLVNVDKRLKLSQAIPKIQIMQDKKRNAELHKNENAKNYYTCNDTSIKNLGFLEFTEVYYKIQKLKTKPIPKLELRVEDYLKNPSITSKMPVLKIYIQEDGNTYLNGELLDIENALSKITTIREAINAKGFILILWFDKNLSFQDYIHVKSQLTAADSNYITIDQNEFIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJW6</accession>
    <name>A0A5C6ZJW6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Beta-carotene hydroxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_06525</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sterol desaturase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016117">
        <property type="term" value="P:carotenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045019">
        <property type="entry name" value="BETA-OHASE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006694">
        <property type="entry name" value="Fatty_acid_hydroxylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31899">
        <property type="entry name" value="PTHR31899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04116">
        <property type="entry name" value="FA_hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0125">Carotenoid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="53"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid hydroxylase" evidence="4">
        <location>
            <begin position="13"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD89852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="149" mass="18271" checksum="DB4598DC49CF9D9A" modified="2019-11-13" version="1">MHTLYWILIFLGVFSTMEFMAWFTHKYIMHGFLWSLHKDHHHKDHKNWFERNDAFFIFYAVVSMICFYLWSYENVWYFLPIAFGIMGYGAAYFLVHDIFIHQRFKVFRNANNWYAKGVRRAHKIHHKHLGKGDGECFGMLLVPFKYFKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJZ9</accession>
    <name>A0A5C6ZJZ9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">MmcQ/YjbR family DNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_08795</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007351">
        <property type="entry name" value="YjbR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038056">
        <property type="entry name" value="YjbR-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35145">
        <property type="entry name" value="PTHR35145"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04237">
        <property type="entry name" value="YjbR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142906">
        <property type="entry name" value="SSF142906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="120" mass="13749" checksum="15A72A17AA9BB2F0" modified="2019-11-13" version="1">MNIEQLQNYCISKKATTEEFPFDADTLVFKVLGKVFALIGLEKWEAGQKAINLKCDPDYAEELRSEYAAIKPGYHMNKKHWNTVDLTGSEISPKFLSQLIDHSYDMVVKGMTKKMRDSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK08</accession>
    <name>A0A5C6ZK08_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="92" mass="10564" checksum="A4A81C99D6DF40A8" modified="2019-11-13" version="1">MKRFEPYRNIRKKAVIFGLPISLFALMMMSILASLMVIIFSFSFGVIIGIFIFNTALYVALTRISNNPQLFQMAKAFPKIISNKRNSGFDYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK37</accession>
    <name>A0A5C6ZK37_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08535</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038727">
        <property type="entry name" value="NadR/Ttd14_AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13521">
        <property type="entry name" value="AAA_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_28" evidence="1">
        <location>
            <begin position="15"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="189" mass="22014" checksum="E3409866D59C1048" modified="2019-11-13" version="1">MEKQLRQDHKPDCIKVVFFGPESTGKSVLCERLAAHYNTVFVSEFSRIYAEAKAQKQQQLSREDVLPIAIGQMALENKQLKNAKNLLICDTDLLETKVYSEYYYDGFCPPSVKKHALLNVYDLYFLTYIDTNWQADGIRDQPNNRQELFNIFEGELQSNKKTYVTLKGDFESKFQTCVQYIDDLLKQLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKB4</accession>
    <name>A0A5C6ZKB4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Mechanosensitive ion channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_03460</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045275">
        <property type="entry name" value="MscS_archaea/bacteria_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30221">
        <property type="entry name" value="PTHR30221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="14"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="81"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="184" mass="20790" checksum="1F59C6C4DEB4A598" modified="2019-11-13" version="1">MRFIMFYEGLQKELIISGFVLLFLLLVRFITNAVIRKIGKKNNINEARIKLICRYVSVTLFLLAILIEAIVFGVALKELSVIFSSIFAVIGIGLFAIWSILSNVTSGIIMFFSFPYKVGDKIRIHDKDFPIEGIIEDIQAFQLHLRENNGDLVTYPNNLMLQKAVTLVQKDAIVDVFDEGSDAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKC5</accession>
    <name>A0A5C6ZKC5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Isochorismate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005801">
        <property type="entry name" value="ADC_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015890">
        <property type="entry name" value="Chorismate_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00425">
        <property type="entry name" value="Chorismate_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56322">
        <property type="entry name" value="SSF56322"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chorismate_bind" evidence="1">
        <location>
            <begin position="102"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="377" mass="42365" checksum="AB476CE954766B62" modified="2019-11-13" version="1">MTKDELLKSVQAHWISNLPFVAYSKPDTALVNAVLQKSDQIHYTLDFEESGFVFAPFNNQEETIIFPSENSKLLKADFVVEAIAENTKADSTLGDETETSAQKQHKVLVEKAISAIADNKFKKVVISREEVLPIDEQSPFTLFENLLQCYPSAMVYIWFHPKVGLWLGATPETLLQVEGLRFKTMALAGTQAYIDTEAVVWDAKNIMEQQLVTNFIEDQLQPVVATLNIMDAETIKAGRLLHLRSHISGILKSDGNKLKHLLQALHPTPAVCGLPKSEAKAFILKNENYNREFYAGFLGELNLSKTTSRNPNRRNVENNAYASITKLSHLYVNLRCMQIKQQNAHLYVGGGITQSSNPEAEWEETVNKLQTMKRVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKG2</accession>
    <name>A0A5C6ZKG2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Glutamate synthase large subunit</fullName>
            <ecNumber evidence="16">1.4.1.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">gltB</name>
        <name evidence="16" type="ORF">ESY86_02300</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="14">Amino-acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glutamate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.1.13" evidence="16"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051538">
        <property type="term" value="F:3 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004355">
        <property type="term" value="F:glutamate synthase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006537">
        <property type="term" value="P:glutamate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00982">
        <property type="entry name" value="gltB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02808">
        <property type="entry name" value="GltS_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002489">
        <property type="entry name" value="Glu_synth_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036485">
        <property type="entry name" value="Glu_synth_asu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006982">
        <property type="entry name" value="Glu_synth_centr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002932">
        <property type="entry name" value="Glu_synthdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00310">
        <property type="entry name" value="GATase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04898">
        <property type="entry name" value="Glu_syn_central"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01645">
        <property type="entry name" value="Glu_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01493">
        <property type="entry name" value="GXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69336">
        <property type="entry name" value="SSF69336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0003">3Fe-4S</keyword>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0288">FMN</keyword>
    <keyword evidence="12" id="KW-0314">Glutamate biosynthesis</keyword>
    <keyword evidence="8" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 16" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="15">
        <location>
            <begin position="17"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00029440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="TXD90811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1501" mass="166933" checksum="787F050E280C849F" modified="2019-11-13" version="1">MLAAQGLYLPEFEHDNCGAGFICSLKGNTSNSIIHKALEILEKLEHRGAVSADGKTGDGAGILIDIPHEFFVKNCEFQLPEFGQYAVSNVFLPKKENQRNFCIEKLELFMKGQGLKILGWRDLPVNSEVIGKIAAETEPFTKQVFIAKGEEHQTDFDFNLKLFTARKQTEHFIIASKLSESARFYLPSLSTKTIIFKGLLIPEDIKLYYIDLQDPSLVTRLALVHQRFSTNTFPTWDLAQPFRYMCHNGEINTLRGNVSRVLSRQELMESDWFGEDIKSIFPIILPGKSDSAQMDMVVELLLMTGRSLPEVMMMLVPEAWERNPLMSQAKRAFYEYNSCIMEPWDGPASIPFTDGNYIGAVLDRNGLRPSRYTVTKDGFVIMSSETGVIDIDPKNIEQHGRLEPGKMFLVDMNQGRIINDAEIKENIVTRYPYQKWLDDNLVHLAKIPAKEGPIKHKEDALAKRQVVFGYTEEDLSVLIKPMAQNAKEPIGSMGNDVPIAVLSEKPQLIYNYFKQLFAQVTNPPLDGIREKLITDISLTLGMDANLFQINENQCRKLKIQNPVISKHDLDKIKNYKSNPHFVVTTISMLYEVDKGLNGLESALEHLVKTASEAIDEGGNIIILSDRGVSKLLAPIPALMACSYVNHELYKIGKRAKVSIVIESAEPREVHHFALLFGYGASAINPYIVNEIVQKQVQQKEIENMDYLTAIKNYNKAIGMGVLKVMNKIGISTLNSYRGSQLFECVGLNTKVVNEYFPNTVTRLQGIGLREIEKEIYKRHKKAYKTNAVDADLNLEFGGQYKWRRHGEKHSFNPLTVAKLQEAVRGNKHETYKEYSYLINEQTKQLMTIRGLFEFANYDPIPLEEVEPWTKIVKRFKTGAMSYGSISKEAHENLAIAMNRIGGKSNSGEGGEDEERFYKHANGDWKNSAIKQVASGRFGVTSNYLTNASEIQIKMAQGAKPGEGGQLPGPKVNPDIAKTRNSTPYVGLISPPPHHDIYSIEDLSQLIYDLKSANREARINVKLVSEVGVGTVAAGVAKAKGDVILISGHDGGTGASPLTSLKHAGLPWELGLAEAQQTLVMNNLRNRVVLECDGQMKTGRDVAIACLLGAEEFGFATAPLVASGCIMMRACHLNTCPVGIATQNPDLRKKFQGKPEHVVNFMYFIAQELREIMAQLGFRTVDEMVGQVHKLNRNKTISHYKALGLDLTPILHQVAVPEGTKLYNTETQDHQLEKALDFEIIRQAHPALFRKEKTVIESKINNRDRAFGAILSNEISKIYGAQGLPENTLKINFTGSAGQSFGAFATKGLTFTINGNSNDYLGKGLSGAKLIVKVPEEATIVPEENVIIGNVALYGATSGEAYINGKAGERFCVRNSGAHAVVEGIGDHGCEYMTGGRAVILGEVGRNFGAGMSGGIAYVYNPKGTFEANCNTEGLNLDEVVIPEDISELKALVENHYNATLSPLAQRLLENWQNELPKFVKILPEEYKQALLRLEEEQKVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKJ8</accession>
    <name>A0A5C6ZKJ8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF4295 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_03940</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025379">
        <property type="entry name" value="DUF4295"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14128">
        <property type="entry name" value="DUF4295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="50" mass="5567" checksum="98AA00449C0591D7" modified="2019-11-13" version="1">MAKKSVASLQTGSKRLTKAIKMVKSPKTGAYMFVESVMAPEFVEEFINKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKK0</accession>
    <name>A0A5C6ZKK0_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Uridylate kinase</fullName>
            <shortName evidence="6">UK</shortName>
            <ecNumber evidence="6">2.7.4.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Uridine monophosphate kinase</fullName>
            <shortName evidence="6">UMP kinase</shortName>
            <shortName evidence="6">UMPK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">pyrH</name>
        <name evidence="8" type="ORF">ESY86_02045</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the reversible phosphorylation of UMP to UDP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>ATP + UMP = ADP + UDP</text>
            <dbReference type="Rhea" id="RHEA:24400"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.22"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="6">Inhibited by UTP.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 6">Pyrimidine metabolism; CTP biosynthesis via de novo pathway; UDP from UMP (UMPK route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the UMP kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.22" evidence="6"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00159">
        <property type="reaction ID" value="UER00275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033862">
        <property type="term" value="F:UMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044210">
        <property type="term" value="P:'de novo' CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04254">
        <property type="entry name" value="AAK_UMPK-PyrH-Ec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01220_B">
        <property type="entry name" value="PyrH_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011817">
        <property type="entry name" value="Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015963">
        <property type="entry name" value="Uridylate_kinase_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005650">
        <property type="entry name" value="Uridylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02075">
        <property type="entry name" value="pyrH_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 6" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AA_kinase" evidence="7">
        <location>
            <begin position="4"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="9"/>
            <end position="12"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>UMP</name>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>UMP</name>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="132"/>
            <end position="139"/>
        </location>
        <ligand>
            <name>UMP</name>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD90767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="235" mass="25736" checksum="2855746B38765360" modified="2019-11-13" version="1">MKYKRILLKLSGEALMGSRQYGIDPERLSEYARDIKEITDLGVEVAIVIGGGNIFRGVAGAMNGMDRVQGDHMGMLATVINGLALQNALEDQDVKTRLQTAIKINEVAEPFIRRKAMSHLNKGRVVIFGGGTGNPYFTTDSAAVLRAIEIEADVILKGTRVDGIYDKDPEKDLNAIKFDHITFAEVLKKGLKVMDTTAFTLSQENNLPIIVFDMNKKGNLLKVVSGENIGTKVNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-02-10" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKL6</accession>
    <name>A0A5C6ZKL6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">FAD-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_02565</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028348">
        <property type="entry name" value="FAD-binding_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42842">
        <property type="entry name" value="PTHR42842"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038984">
        <property type="entry name" value="FAD_binding_protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="519" mass="57122" checksum="EECCE0F15E0A5552" modified="2019-11-13" version="1">MIKALQLRITLEEEKQSNILLSKASQNLNLKLSDISAVKVLRKSIDARKKQIMLNYKVEVYINEPAPENSAYTFDYKDVSAAKPIHIIGFGPAGMWAALRCIELGFKPIVLERGKNVQDRRRDLKAINQDHEVNEDSNYCFGEGGAGTYSDGKLYTRSLKRGDVRKIFENLVYHGATDQILVDAHPHIGTNKLPKVVQNIRETILNHGGEIHFETRVVDFGIKNKHINSLTLHNGDELAVDKVILATGHSARDMFYLLQAKNIELKAKSFAMGVRVEHPQQIIDGIQYHCKGENRDELLPAASYSLVEQVRDRGVYSFCMCPGGFIVPAATANGEVVVNGMSPSKRNNAFANSGIVVEINAEKDLYKYEQFGALKGLEYQKDLERLAFTAGGRNQTAPAQRLTDFVEGKLSADLNPTSYQPGLNSAPLHSLLPKLIGGSLRKGFKAFGEKMHGYYTAEANVIGVESRTSSPVNIPRNENLAHPEIENLFPCGEGGGYAGGIVSAAMDGERCAEAACEMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKQ7</accession>
    <name>A0A5C6ZKQ7_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">3-hydroxy-3-methylglutaryl coenzyme A reductase</fullName>
            <shortName evidence="3">HMG-CoA reductase</shortName>
            <ecNumber evidence="3">1.1.1.88</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_09280</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>(R)-mevalonate + CoA + 2 NAD(+) = (3S)-hydroxy-3-methylglutaryl-CoA + 2 H(+) + 2 NADH</text>
            <dbReference type="Rhea" id="RHEA:14833"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:36464"/>
            <dbReference type="ChEBI" id="CHEBI:43074"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.88"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Metabolic intermediate metabolism; (R)-mevalonate degradation; (S)-3-hydroxy-3-methylglutaryl-CoA from (R)-mevalonate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the HMG-CoA reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.88" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00257">
        <property type="reaction ID" value="UER00367"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140643">
        <property type="term" value="F:hydroxymethylglutaryl-CoA reductase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004420">
        <property type="term" value="F:hydroxymethylglutaryl-CoA reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015936">
        <property type="term" value="P:coenzyme A metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00644">
        <property type="entry name" value="HMG-CoA_reductase_classII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.770.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002202">
        <property type="entry name" value="HMG_CoA_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004553">
        <property type="entry name" value="HMG_CoA_Rdtase_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023074">
        <property type="entry name" value="HMG_CoA_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009023">
        <property type="entry name" value="HMG_CoA_Rdtase_NAD(P)-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009029">
        <property type="entry name" value="HMG_CoA_Rdtase_sub-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10572">
        <property type="entry name" value="PTHR10572"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00368">
        <property type="entry name" value="HMG-CoA_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00071">
        <property type="entry name" value="HMGCOARDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55035">
        <property type="entry name" value="SSF55035"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56542">
        <property type="entry name" value="SSF56542"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00532">
        <property type="entry name" value="HMG_CoA_R_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50065">
        <property type="entry name" value="HMG_COA_REDUCTASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2 3 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="438" mass="48729" checksum="6B6A56E1BE6588E6" modified="2019-11-13" version="1">MSKTISGFSKLSKTEKIDWLTSTYFSNPEQAKYVLEQYANNDQKLQQLHDEFIENTISNYYLPFGVAPNFDINGKTYAIPMAIEESSVVAAASKAAKFWQSRGGFKATVLSTEKIGQVHFMFQGDKDRLQVFFEQIKPKLIDATKALTKNMEQRGGGILDIELRDKTEAIANYFQLHATFETLDAMGANFINSCLEQFAKTLKEEAEHYEAFSTEERQLQIIMSILSNYVPQCIVRAEVSCKVEELSDNKTIAAEDFAEKFIQAVRIAEVEPYRAVTHNKGIMNGVDAVVLATGNDFRAVEAGVHAYAARTGSYSSLSHAKVEHGVFTFWMDLPLALGTVGGLTKLHPLVKVALEMLGNPSAKELMQIVAVAGLAQNFAALRSLTTTGIQEGHMKMHLMNMLNQYEATSEEKSKLIEYFKTHVVSNASVEEAVAGLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL03</accession>
    <name>A0A5C6ZL03_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Crp/Fnr family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_04760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="1">
        <location>
            <begin position="32"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="191" mass="21596" checksum="30604544208C30AB" modified="2019-11-13" version="1">MANPIFKAVYSHPELKTADLEAIQAAHEPFGFSKGEVFLKAGQTANNYFLIETGLLRSFAHDFDGNEITTGFTGANEIMIEVASLFQRKPSVENFIALTDGVAWKIEFEDFQKLYHDIPAFNEWGRAWMSHQLFVAKQRNIDMLTKSATVRYVNLLKDKPQIVLEAPLKHIATYLGVTNTSLSRIRKEIAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL13</accession>
    <name>A0A5C6ZL13_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">30S ribosomal protein S18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">rpsR</name>
        <name evidence="5" type="ORF">ESY86_00100</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the bacterial ribosomal protein bS18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00270">
        <property type="entry name" value="Ribosomal_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001648">
        <property type="entry name" value="Ribosomal_S18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036870">
        <property type="entry name" value="Ribosomal_S18_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13479">
        <property type="entry name" value="PTHR13479"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01084">
        <property type="entry name" value="Ribosomal_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00974">
        <property type="entry name" value="RIBOSOMALS18"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46911">
        <property type="entry name" value="SSF46911"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00165">
        <property type="entry name" value="S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD91038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="98" mass="11245" checksum="8B7C22DD95DCB140" modified="2019-11-13" version="1">MSSIEQQAKGKKDGEIRYLTPLNIDTSKAKKYCRFKKSGIKYVDYKDGNWLLGFVNEQGKILPRRLTGTSLKYQRKVSVAVKRARHLALLPYVADLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLI5</accession>
    <name>A0A5C6ZLI5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Thiol:disulfide interchange protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_04835</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003834">
        <property type="entry name" value="Cyt_c_assmbl_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028250">
        <property type="entry name" value="DsbDN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036929">
        <property type="entry name" value="DsbDN_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11412">
        <property type="entry name" value="DsbC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02683">
        <property type="entry name" value="DsbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="202"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="247"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="281"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="323"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="358"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="393"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="430"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="468"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="domain" description="DsbC" evidence="4">
        <location>
            <begin position="36"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="DsbD" evidence="3">
        <location>
            <begin position="210"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF11412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="677" mass="74644" checksum="ED18A14311DEA366" modified="2019-11-13" version="1">MKYVILLLIGCYLGITNVSAQILEPVKWTTSIEKVSETEYDLIATSKIDAGWHLYSQNVPEGGPIPTTFTFETNADFELLGKVVEEEGRTINDPVFNMRIKFFENSAQFRQRIKVLNEELSIVKGEVEFMVCDDTRCLPPTYIDLNFNLDGSNSNLTSSENASEGNSAVDFQNPEKSEAAAQSEKATVANETKAEGEVQEGLWTIFILGLGAGLIALFTPCVFPLIPMTVSFFTKQSKNKAQGIKNAFIYGLCIIVIYVILGTGVVAIFGASAINEFSTSVTFNLLFFIILVIFAVSFLGAFEIMLPNSWANKIDSKADKGGFTGIFFMALALAIVSFSCTGPFVGNIIVLSATKGGLAPMIGMLGFSIALALPFGLFAAFPGWLNSLPKSGGWLNTVKVVLGFLELAFAFKFLSQADLVLQLHFLEREVFIAIWIAIFGALAFYLFGKIKLPHDSPLTHISVGRLSLGLLVLSFTIYMIPGLWGAPLNLISAFPPPLDYAESPYGVGNSKTSGSFISNDNKELPEGAHLLAPHQILAFNDYDKGMAYAKKVNKPVMLDFTGWACVNCRKMEQNVWPEDQVLNVLKNDVILISLYVDDKRKLPENEVVASKLRPGKQLKYIGQKWSEFQAIKFKTNTQPYYALLDTDGKVLNKPVGYTPDVEEYLTWMQEGVEAFEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLS8</accession>
    <name>A0A5C6ZLS8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DeoR/GlpR transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_01335</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014036">
        <property type="entry name" value="DeoR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001034">
        <property type="entry name" value="DeoR_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018356">
        <property type="entry name" value="Tscrpt_reg_HTH_DeoR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00455">
        <property type="entry name" value="DeoRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08220">
        <property type="entry name" value="HTH_DeoR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00037">
        <property type="entry name" value="HTHLACR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00420">
        <property type="entry name" value="HTH_DEOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00894">
        <property type="entry name" value="HTH_DEOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51000">
        <property type="entry name" value="HTH_DEOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH deoR-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD91258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="251" mass="27763" checksum="3891DBCCEAB9AD9B" modified="2019-11-13" version="1">MKRHKDILEKLEKEKHLEVSDLCEHLGVSAVTIRKDLKFLETKGLLHRTHGGASLDNPYINERTVIDKAKVCVEQKTSIAKMAASRILENDSILIASGTTVQIFSKHITAKTKLTVITSSIYVALNLIDNTDIEIIQLGGYLRHSSASVIGKYAELILKDISCSTLFLGVDGIDLDYGLSTTNIEEAALNKKMMKSAQKVIVLADSSKFGKKSFARIADLSEVHEIITDRGISSLIKKKLEEKEIKVTIID</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLU7</accession>
    <name>A0A5C6ZLU7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002491">
        <property type="entry name" value="ABC_transptr_periplasmic_BD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01497">
        <property type="entry name" value="Peripla_BP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50983">
        <property type="entry name" value="FE_B12_PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe/B12 periplasmic-binding" evidence="1">
        <location>
            <begin position="143"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="428" mass="47807" checksum="5DDC8556E42B4EB1" modified="2019-11-13" version="1">MRKRSIIWPWKNKSVNPIGSLRPLKSKSATNLTFEPLKPKLLKSAVCLFIAIAFLSCKSDKSSNASENSKIPSATINDETLQLSYAKGFSVKTFENFSVLNVSNPWPNADESYKYALIPRENAAKITLNKEDFDGMLLTPIQSIVVTSTTHIPALELLGVEQSLVGFPGINYISSEKVRARIDQGHVRELGKNEGINTEVLLEVRPDVVIAFGVDGSNKSMDVIAKAGIPVIYNGDWVEKSPLAKAEWIKFFGVLYNKQKKADSIFNQIVTGYEEAKKLATTVNHVPTILAGAMYKDVWYLPSGTSPEAQFLNDANLNYLWRDTEGKGSLELSFESVFQKAKNAELWLSPSYYTSLEAMLKANTHYDQFEAYKNKSVYSFASTVGATGGVTYYELGMARPDLVLKDMIKIGHPELLEDYELNFFRKMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLV2</accession>
    <name>A0A5C6ZLV2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SPOR domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07675</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042834">
        <property type="term" value="F:peptidoglycan binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040495">
        <property type="entry name" value="HU-CCDC81_bac_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041268">
        <property type="entry name" value="HU-CCDC81_bac_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007730">
        <property type="entry name" value="SPOR-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036680">
        <property type="entry name" value="SPOR-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18174">
        <property type="entry name" value="HU-CCDC81_bac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18175">
        <property type="entry name" value="HU-CCDC81_bac_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05036">
        <property type="entry name" value="SPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110997">
        <property type="entry name" value="SSF110997"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51724">
        <property type="entry name" value="SPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SPOR" evidence="1">
        <location>
            <begin position="232"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="312" mass="34996" checksum="4D8DDC5639D2046A" modified="2019-11-13" version="1">MQLETYISDLLYRYDCVIVPQFGAFLAQRISAQVHETTHSFHPPKKKVSFNEQLQQNDGLLANYIAEVEKIPYQVAVEKIAKKIKTIKSYLTQGETIALNNIGDLTLNAEGHISFEPSEHINYLTDAFGLSQFTSAAVSRTTHKATVEALEERTPIAITPERRQSRPYLKYAAIALIALSITGFAGSNWYLNSIETQNQVAQEEANDQMDARVQQATFVIENPLPAATLQVEKPSGNYHIVAGAFRVEANSDKKVEQLREKGYKARKIGSNRYGLHEVVYASYTDRIEALQALRAIKREHNAAAWLLVKALD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLW7</accession>
    <name>A0A5C6ZLW7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADPH:quinone oxidoreductase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_01550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="10"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="325" mass="35187" checksum="3DCB91A4D5A20FEE" modified="2019-11-13" version="1">MKAIRCKTYGPPSNLKLEDIGSLHAGPKEVVVEVKACGLNFPDTLIIQGLYQFKPELPFTPGSDIAGVVKEIGEDVKHLKVGDEVFGFVAHGGLAEEVIVPRNACFPKPPQMDFPVAASFMMAYGTSYYALKDRAKLEEGETLLVMGASGGVGLAAVELGKLMGAKVIAAASTQEKLELCKAYGADELINYTEQDLKSTLKELTNGKGVDVIYDPVGGDFSEQAFRGIAWNGRFLVVGFAAGDIPKIPLNLPLLKGASIVGVFWGGFAMKYPKDNMANTMTLMQWHAEGKLKPHIHKIVPLEETKEALEEMMNRKVKGKMVVQIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLX2</accession>
    <name>A0A5C6ZLX2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07795</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043742">
        <property type="entry name" value="DUF5687"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18940">
        <property type="entry name" value="DUF5687"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="174"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="281"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="309"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="353"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="378"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="423"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="448"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="492" mass="56546" checksum="5F1EA53C373C32D6" modified="2019-11-13" version="1">MTLKQFLNLEWKQYFRSSYWQKSIAINILLVFFALYFIVMFLFLGIALYPGLKEAFPDQDPLNIVNSYMFYYILIDLVLRFFFQKLPVMSVKPLLTLPVKRSRVVHYVLRKSVFSFFNFLPLFAFVPFSIMLLVNGYPTGSVLAWFFLTILMSLTINFLNFIIESFSSETELSFLPIIVIAGGLYALDFFNIVSISGLVAEAYASIFNNPIFLLVPLALLIGVYLLNHRLLKSKLYLDSSLKSKVETVNASAMEWTKRFGDIAPFLQLDLKLIWRNKRTKSSVWMLVLGLLYGLFFYPQEQMSSPPFYAFVGIFVTGIFLINFGQFIPAWDSGYYKMLMSQNIKYEQYLKSKFTLMAMSVILLFVLSIPYVYFGWEILVAHFAAAIYNIGVNTHVILIGGSYNRKKIDLNQRAAFNYQGTGAVQWLIGIPLMLLPLAIFAGVYYLANFEFACATLAAFGIIGIVLHPKLMTYITQRYTNSKYKMIDAFSQDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM49</accession>
    <name>A0A5C6ZM49_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribonuclease Y</fullName>
            <shortName evidence="5">RNase Y</shortName>
            <ecNumber evidence="5">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 8" type="primary">rny</name>
        <name evidence="8" type="ORF">ESY86_00775</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Endoribonuclease that initiates mRNA decay.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the RNase Y family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="5"/>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00335">
        <property type="entry name" value="RNase_Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006675">
        <property type="entry name" value="HDIG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017705">
        <property type="entry name" value="Ribonuclease_Y"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022711">
        <property type="entry name" value="RNase_Y_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12826:SF15">
        <property type="entry name" value="PTHR12826:SF15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12072">
        <property type="entry name" value="RNase_Y_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="SSF54791"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00277">
        <property type="entry name" value="HDIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03319">
        <property type="entry name" value="RNase_Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2 5" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="HD" evidence="7">
        <location>
            <begin position="339"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD91156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="525" mass="58288" checksum="E3685BC73D6F7FA1" modified="2019-11-13" version="1">MDTNIILFIVGGVIIGVILGFITAKTLEKSNASKLIKNAEADAKSILKDANSEGESIKKEKILQAKEKFIELKSEHEKVILGRDKKMADAEKRTKDKESQVSSELAKYKKSNQSLEDKIKDYDFKLEYLDKKNDELDKAQKSQIKQLEVISSLSAEDAKSQLIESLKGEAKSDAMAYVQNAMEEAKLTAEQDAKKIIINTIQRIGTEEAIDNCVSVFNIESDDVKGRIIGREGRNIRAIEAATGVEIIVDDTPEAIILSCFDSVRREVARLSLHKLVTDGRIHPARIEEIVQKTEKQIEQEIIENGKRTVIDLGIHGLHPELIKLVGRMKYRSSYGQNLLQHSREVAKLCGVMAAELGLNPKLAKRAGLLHDIGKVPSSEADMETPHAILGMQWAEKHGEKPEVCNAIGAHHDEIEMTTLLAPIVQVCDAISGARPGARRQVLDSYIQRLKDLEEVAFGFNGVNKAYAIQAGRELRVMVESDKVSDEDASNLSFEISQKIQTDMTYPGQVKVTVIRETRAVNIAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM82</accession>
    <name>A0A5C6ZM82_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GLPGLI family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_02335</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005901">
        <property type="entry name" value="GLPGLI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09697">
        <property type="entry name" value="Porph_ging"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01200">
        <property type="entry name" value="GLPGLI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023010027" evidence="1">
        <location>
            <begin position="22"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="273" mass="31433" checksum="99CA703B7C4B06F5" modified="2019-11-13" version="1">MNTLRKLSLLVFFVLTGHLNAQEFTGEATYKTHRKVNIKIDSSKSKISTDQQKQFNEQLKKQFQKTFMLSFSKEESLYKQEEALAKPNPMGNAAQIVFSSNTDVLYKNIKTQTYVEQTDILSKSFLIKDSIKDIAWQLENETKNIGNYTCFKATYTYQHPIRDFENDKDSLRFEARKITAWYTPQIPVSNGPELYQGLPGLILEINDGQQTIICSKIQINPKKTNKIEAPDTGKEVTQTEFDTIKDQKNKEFLERYGVKSKDGSNRIEINLGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMA6</accession>
    <name>A0A5C6ZMA6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ESY86_02965</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015408">
        <property type="term" value="F:ABC-type ferric iron transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055072">
        <property type="term" value="P:iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03259">
        <property type="entry name" value="ABC_Carb_Solutes_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015853">
        <property type="entry name" value="ABC_transpr_FbpC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030287">
        <property type="entry name" value="FbpC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24220:SF675">
        <property type="entry name" value="PTHR24220:SF675"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 8 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0410">Iron transport</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="2"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD90932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="337" mass="37518" checksum="17118F303FE9833B" modified="2019-11-13" version="1">MLTIDSLSKSFDKGKNYAIEDVTFNLMAGHVCAIVGESGSGKTTLVRLIAGLERPDHGSIAMDGKVIASLNKFVQPEKRKIGLVFQEYALFPHLTILDNILYGISKVKHKKQRAQDMLDLVGLDDMGSRYPHQLSGGQQQRVALARALAPEPSLLILDEPFSNLDTMLRTQLRNEVFDIIKKTEVTVLFVTHDTQDALSVADEILILQNGKVIQKDVASNLYVKPSTLYVASLFGSTVHINKNLQNAFRCPLKETCCHAIRNEKIKVNPSPDDFDCEYLTTAQVIKKIELGDSIQLLLKLESGEQLTVMTQDKNIADTINIGFNSKDILEFDQEQES</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMK7</accession>
    <name>A0A5C6ZMK7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alkaline phosphatase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_04015</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07389">
        <property type="entry name" value="MPP_PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018946">
        <property type="entry name" value="PhoD-like_MPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038607">
        <property type="entry name" value="PhoD-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09423">
        <property type="entry name" value="PhoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PhoD" evidence="1">
        <location>
            <begin position="78"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="340" mass="38759" checksum="8C7BE4358658437A" modified="2019-11-13" version="1">MIRYCSIFLLFLSIYACKTRDNISKSESEDLVIAFGSCNKQYEPNLLWDDVLSNKPKVWVWGGDVVYSDTEDMAVLEKSYTMQHSQEAYQLAESEMRILGTWDDHDYGKNDAGAGYPKKNESQQLFLDFLNVPKTDARRDREGVYHSELITTPKGSVKLIILDTRFFRTALTDANVKGKRYVPNTYGEGTVLGEQQWQWLQKELENSLADFNVIVSSIQFLSSEHGFETWGNFPHEVDKMLKTIVASKAKNVLLTSGDRHISEFSKRTVKGLSYPIIDFTSSGLTHAYSSFDGEPNRFRSGKVVSEISFGVLKFNFSSKTVTMQMRGDGNTLQQELIQRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMP4</accession>
    <name>A0A5C6ZMP4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NADP-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_03060</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041694">
        <property type="entry name" value="ADH_N_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045010">
        <property type="entry name" value="MDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43205">
        <property type="entry name" value="PTHR43205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16884">
        <property type="entry name" value="ADH_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="PKS_ER" evidence="2">
        <location>
            <begin position="17"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="333" mass="36184" checksum="C0FAB3D5DA641930" modified="2019-11-13" version="1">MNTTKTINLNSRPVGKPQLTDFEFTTTEIPELKDGELLLRTTYVSVDPYLRGRMSDAKSYIAPFELHKPIESGSIAEVLESKDSNFSKGDYVSGSLAWKETQVAKAKDLMKVDPDKAALSAYLGILGMTGLTAYIGLTEIGKPKKGETLLVSGAAGAVGSVVGQIGKILGLRVVGIAGTDEKVAMLKSEFGFDAGINYNTTKQMSEAIAKACPDGVDVYFDNVGGEISEAVLFNINKFSRTINCGAISVYNNKELPKSISVQPFLIKKSASMQGFVIFDYVDQHPAGIKQLTEWLATEKLTYTETIREGFENIPQAFMDLFDGKNKGKMVVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN01</accession>
    <name>A0A5C6ZN01_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF1573 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05905</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011467">
        <property type="entry name" value="DUF1573"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07610">
        <property type="entry name" value="DUF1573"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023033630" evidence="1">
        <location>
            <begin position="20"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="141" mass="15198" checksum="AC7B190DC316FE87" modified="2019-11-13" version="1">MKNLAIVLCVAFMSLGAFAQEKVAKIEFKSDVIDYGTIEKGSDGVRVFEFTNTGNAPLIISNVKSTCGCTVPKKPDGPIMPGETGEISVKYDTNRVNPIRKTITVSSNAETPTVALKIKGLVVDSSKNSVLEKRDKSVMEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN15</accession>
    <name>A0A5C6ZN15_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">PspC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_01230</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007168">
        <property type="entry name" value="Phageshock_PspC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04024">
        <property type="entry name" value="PspC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="135"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="263"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="308"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="349"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="PspC" evidence="7">
        <location>
            <begin position="108"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD91239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="615" mass="69553" checksum="DC6701AD13A8CBEC" modified="2019-11-13" version="1">MNKTVNINLAGIFFHIDEDAYLKLQRYLEAIKRSFTNSQGRDEIIADIEARIAELFNERMQNDKQVIGVKEVDEIVTIMGEPEDYLIDDDIFEDEPRQGYAKSNTNTKRLFRDTDNSYIGGVCSGLSHYLGLDPIWIRFIWILLILSAGTGVLVYILLWILVPEAKTTAEKLMMRGEPVNISNIEKKIKDGFENVSNSVKNVDLKKHGDKLKEGFEHVSGSINEGVKRADFSKQGQRFKSTSTSFFDAVGTIVMFILNVFAKFFGLLLIIFGALLLLGLIISVFSLGTSSYFHPWWMDYPEVLNTTGMPIWLGGFALFLFLGIPFFFISYLGLKILINNLKSIGKVAKLTLLGLWVIALFSIIFMSARQASYFSSENSTLTNERLNLNTNDTLQIKMVSTQLNRMNSNSFRNNSFEITYDENDQKVIYSRNIHVSVRSTKDSVATIRIEKQARGRNFMEARKTADFIDYHYEINNNQLLLDNFIVTDYDNKFLDQKVDITIYLPEATLFRMHQNTSSFLNSHASGGNLMSFSDVGHLLKVTEDGNTCLDCLEEERFKVKVDLKDGGASLKINENGIEANSNTNSFKADSTGIKAKTDSVRVNIDSNGIEISTDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNH5</accession>
    <name>A0A5C6ZNH5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Efflux RND transporter periplasmic adaptor subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_04075</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022842322" evidence="2">
        <location>
            <begin position="26"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="3">
        <location>
            <begin position="65"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD90553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="380" mass="40993" checksum="224F66C9B8EB2137" modified="2019-11-13" version="1">MNTITKNLMPLLLLILASSCGNDEAGQNPASAKQRAMVLPVIEVPTKTVTVYTDYPTSIEGIINSEVRAKISGYITDVLVDEGQKVRKGQTLFKLETQSMNQDAAAAQANVNAAQVEVDKLKPLVDKSIISPVQLETAEAKLQQAKSAYNSIASNIDYGTITSPVDGYVGSIRLRKGALVSPSNATPLTTVSDISEVYAYFAMNEKEYLDFIQNAKGETKEEKINNMPEVILILANGTEYGAKGKIQTINSQVNKQTGTVSFRAQFDNANGILNNGNSGVIKVPTVFENVVVVPKSSTFENQNNRFVYTIKKDSSDATVAASKPIIIKGQSGNLYLIDSGLEKGETIIAKGLSKLSDGMAVQPNKVDFDSIAQPIIKEFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNI8</accession>
    <name>A0A5C6ZNI8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Pyridoxal phosphate homeostasis protein</fullName>
            <shortName evidence="1">PLP homeostasis protein</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_00940</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02087">
        <property type="entry name" value="PLP_homeostasis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011078">
        <property type="entry name" value="PyrdxlP_homeostasis"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10146">
        <property type="entry name" value="PTHR10146"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004848">
        <property type="entry name" value="YBL036c_PLPDEIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00044">
        <property type="entry name" value="TIGR00044"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ala_racemase_N" evidence="4">
        <location>
            <begin position="3"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="1 2">
        <location>
            <position position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR004848-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD91185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="220" mass="24940" checksum="26D49E7B0C9A5D6C" modified="2019-11-13" version="1">MSITNNLETINSKLPEEVKLVAVSKTKPVSELMEAYDAGQRIMGENKVQEMVEKYEKMPKDIQWHMIGHVQRNKVKYMAEFVDLIHGVDSLKLLKEINKQAKKHERVIDCLFQLKIAEEDSKFGMSAKDAKSLISSEAFLELKNIRITGLMGMATFTDDTDQVRSEFKRLKTIFEDLKPIASNNCDLKIVSMGMSGDYAIAIEEGSNMVRIGSRIFGARD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZP14</accession>
    <name>A0A5C6ZP14_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">4-hydroxy-tetrahydrodipicolinate synthase</fullName>
            <shortName evidence="9">HTPA synthase</shortName>
            <ecNumber evidence="4 9">4.3.3.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">dapA</name>
        <name evidence="11" type="ORF">ESY86_01060</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 9">Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>L-aspartate 4-semialdehyde + pyruvate = (2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H(+) + H2O</text>
            <dbReference type="Rhea" id="RHEA:34171"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:67139"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="4.3.3.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer; dimer of dimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9 10">Belongs to the DapA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Was originally thought to be a dihydrodipicolinate synthase (DHDPS), catalyzing the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to dihydrodipicolinate (DHDP). However, it was shown in E.coli that the product of the enzymatic reaction is not dihydrodipicolinate but in fact (4S)-4-hydroxy-2,3,4,5-tetrahydro-(2S)-dipicolinic acid (HTPA), and that the consecutive dehydration reaction leading to DHDP is not spontaneous but catalyzed by DapB.</text>
    </comment>
    <dbReference type="EC" id="4.3.3.7" evidence="4 9"/>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00017"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008840">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00950">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00418">
        <property type="entry name" value="DapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005263">
        <property type="entry name" value="DapA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002220">
        <property type="entry name" value="DapA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020625">
        <property type="entry name" value="Schiff_base-form_aldolases_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12128">
        <property type="entry name" value="PTHR12128"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00701">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001365">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00146">
        <property type="entry name" value="DHPICSNTHASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01130">
        <property type="entry name" value="DHDPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00674">
        <property type="entry name" value="dapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00666">
        <property type="entry name" value="DHDPS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword evidence="9 10 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 9" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0704">Schiff base</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="9">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="9">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </ligand>
    </feature>
    <feature type="site" description="Part of a proton relay during catalysis" evidence="9">
        <location>
            <position position="46"/>
        </location>
    </feature>
    <feature type="site" description="Part of a proton relay during catalysis" evidence="9">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR001365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD91207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="297" mass="32119" checksum="862495553C6CC104" modified="2019-11-13" version="1">MSKFHGTGIAIITPFNQDQTVDHKALANLVNFNIENGTNYIVISGTTGESVTITKQEKTEIIETIVKASNKRVPLVLGIGGNNTAAVIEEINTTDLTGIDAILSVSPYYSKPTQEGIYQHFKAISKACPVDIILYNVPGRTASNMLPDTTLRLARDFKNIVAVKEAGNNVGQYLLLLRDKPEDFSIISGDDDLVLGIVLAGGAGVISVIGQALPKQFSKMIQLGLEGKVKEAYNIHFALMEITALIFAENNPSGVKAVLEALELSKPTVRLPLVEATDGLKEKIKLALEKIEEQFKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZQQ8</accession>
    <name>A0A5C6ZQQ8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphoribosylaminoimidazole-succinocarboxamide synthase</fullName>
            <ecNumber evidence="7">6.3.2.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">SAICAR synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">purC</name>
        <name evidence="9" type="ORF">ESY86_01150</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate + ATP + L-aspartate = (2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate + ADP + 2 H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:22628"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58443"/>
            <dbReference type="ChEBI" id="CHEBI:77657"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the SAICAR synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.6" evidence="7"/>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00131"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004639">
        <property type="term" value="F:phosphoribosylaminoimidazolesuccinocarboxamide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00137">
        <property type="entry name" value="SAICAR_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028923">
        <property type="entry name" value="SAICAR_synt/ADE2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018236">
        <property type="entry name" value="SAICAR_synthetase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01259">
        <property type="entry name" value="SAICAR_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01058">
        <property type="entry name" value="SAICAR_SYNTHETASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAICAR_synt" evidence="8">
        <location>
            <begin position="21"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD91223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="319" mass="36319" checksum="3844BBC02C343618" modified="2019-11-13" version="1">MSVANKTIIDTNFEFPKQKSLYKGKVREVYNINDEQLVMVATDRLSAFDVVMPRGIPYKGQILNQIATSMMKATEDLVPNWLTATPDPNVAVGHLCAPFKVEMVIRGYLSGHAAREYKAGKRELCGVKMPNGMKENDKFPDPIITPATKAEMGDHDEDISREAILKRGIVSEKDYSVLEEYTRKLFQRGSEIAAMRDLILVDTKYEFGKTKSGKIVLIDEIHTPDSSRYFYKDGYQKRQNANEAQKQLSKEFVRQWLIENGFQGKAGQTPPEMSDAYIESVSERYIELYEKIMGQAFVKGDVADIQNRIEMNVLKYLKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZRA7</accession>
    <name>A0A5C6ZRA7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="11">4-hydroxy-tetrahydrodipicolinate reductase</fullName>
            <ecNumber evidence="11">1.17.1.8</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">dapB</name>
        <name evidence="11" type="ORF">ESY86_00630</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DapB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.17.1.8" evidence="11"/>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008839">
        <property type="term" value="F:4-hydroxy-tetrahydrodipicolinate reductase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022663">
        <property type="entry name" value="DapB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000846">
        <property type="entry name" value="DapB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022664">
        <property type="entry name" value="DapB_N_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023940">
        <property type="entry name" value="DHDPR_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20836">
        <property type="entry name" value="PTHR20836"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05173">
        <property type="entry name" value="DapB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01113">
        <property type="entry name" value="DapB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000161">
        <property type="entry name" value="DHPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00036">
        <property type="entry name" value="dapB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01298">
        <property type="entry name" value="DAPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword evidence="8" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="6 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DapB_N" evidence="9">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="DapB_C" evidence="10">
        <location>
            <begin position="102"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF05173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD91130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="233" mass="25392" checksum="05BCF5C7DA309E38" modified="2019-11-13" version="1">MNIALLGYGKMGKTIETIGINRGHHIVLKYDGGAENFNLENCDVAIDFSLPTAAVNNISTCLKAGVPVISGTTGWLKDYDKIVALCKENKGTFLYASNFSLGVNIFFKLNATLAKLMSKLEQYKANITETHHTQKRDAPSGTAITLAEGLIENSDYSSWTLDSPKAKQLGIEAKRIDDVPGTHEVVYKSQEDSIQITHTAHSRQGFALGAVIAAEFVHDKKGIFTMKDVLNIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6Z9B9</accession>
    <name>A0A5C6Z9B9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20750</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000117">
        <property type="protein sequence ID" value="TXD85868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="68"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD85868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="270" mass="31116" checksum="9C965EB66E284033" modified="2019-11-13" version="1">MKKLLVRIASNLFPNQITSFAYDQLTNPQVRKLRENELGTLEKAEKEKYKFKDFDIQLYTWKGGDKKVLLIHGWEGQAGNFSDLIEKLLADGFTVHSFDAPSHGFSSKGRTSLFEFTELVGILIKKFDVKLLVSHSFGGVATTYALFENQDIEIEKYVLITTPDKFIERIDDVSEMVGINEKVKNRLISRLENETNNDVRNLNVSEFVKSINVKKSLIIHDIDDKVIPISRSKNVHQNWTESEFMEIEGTGHFRILRTEKVINKVIDYLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6Z9W6</accession>
    <name>A0A5C6Z9W6_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF5723 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_20460</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000078">
        <property type="protein sequence ID" value="TXD86244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043781">
        <property type="entry name" value="DUF5723"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18990">
        <property type="entry name" value="DUF5723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023007677" description="DUF5723 domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5723" evidence="2">
        <location>
            <begin position="43"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="441" mass="48683" checksum="F89899D634E5CA15" modified="2019-11-13" version="1">MKNFSLALGFCFLLSFQFSHSQSYIGHTVDNYAGIHGVVYNPSSIVGSNFKADINLASASVFGGSDYFGINVSDLIKSDGGFDFEEDSNRFPSEANNFFINTDIVGPSFMFNLNKKSSIGIITRGRGILNLNNINGQLYENIIDEFDTNDDFNFNSENLSGTIHAWSEIGLSYGRILLAKQNQMLKAGVTLKYLMGAGGVYINSPGLQGQYTAASKNLTTRGFLNYGSTQGFDNNDIDFGNLSSGFGMDLGFTYQWHPNRENDDVRYFQDPYKLKVGLSITDIGSINYEDAETTSYDLNASVSTLTLEDDLEAFLDNNYNNTSIGQSAKFQLPTALHVLVDYRLTKKFLVSAQADMSLVKQDNELTNNVINTFTLAPRLETKWFSLYAPLSLRQYGDFAFGTGIRLGPLTVGSASVFSNLLSDSSKTTDVFVGLNIPIYRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAD3</accession>
    <name>A0A5C6ZAD3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF1361 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000035">
        <property type="protein sequence ID" value="TXD86890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009793">
        <property type="entry name" value="DUF1361"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07099">
        <property type="entry name" value="DUF1361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="144" mass="17022" checksum="56A1DDEECA5DA394" modified="2019-11-13" version="1">MLFLPNAPYIVTDLLHLQNSDRYLMWLDVLVILSFATNGLALYFLSLYDMEQSLKRFFNPKFTKVILVFIILLTAFGIYLGRFLRYNSWEILNHPFDILLDVGHILFQPNIEAWMFTLTFASFLAMLYWTLKTFTISEDSNEKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAE1</accession>
    <name>A0A5C6ZAE1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000126">
        <property type="protein sequence ID" value="TXD85819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="39"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD85819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="94" mass="10752" checksum="0F93A1CD99D82C4F" modified="2019-11-13" version="1">MGKSINAKELIAKRYGKEGSKERGEFREDAFSYYFGEIIKNRRKELHMTQENLAEKVGKKRPYISRIENGEDIQLSNFALLANALGLSIQLTAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAX7</accession>
    <name>A0A5C6ZAX7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fructosamine kinase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18065</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the fructosamine kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000029">
        <property type="protein sequence ID" value="TXD87133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016477">
        <property type="entry name" value="Fructo-/Ketosamine-3-kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12149">
        <property type="entry name" value="PTHR12149"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03881">
        <property type="entry name" value="Fructosamin_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006221">
        <property type="entry name" value="Ketosamine-3-kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR006221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="283" mass="32497" checksum="F32645963DA76E72" modified="2019-11-13" version="1">MFPSALKNHLEERFSLRITSAEALSGGDINEVYLLKTNSDYFVVKLNAVNKFPDMFEKESAGLKALRDTETIDIPEVLSYGDFEAHTYLIMAYRKEGAKQPDFWEGFGTQLADLHQHSNARFGFEADNYYGSLPQYNDYCDSAHAFYIEQRLKPQFKLARDNGYEFKHLDAFYKQLESLIPDEKPALLHGDLWSGNYLTNSKGEPCLVDPAVAYGPREMDLAMMRLFGGFDPLLFQAYDAAFSLEPAWKDRIKLWQLYYILGHVNLFGGHYYAQAKTIIAFYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAZ8</accession>
    <name>A0A5C6ZAZ8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF4173 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_18980</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000035">
        <property type="protein sequence ID" value="TXD86896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025231">
        <property type="entry name" value="DUF4173"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13777">
        <property type="entry name" value="DUF4173"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="164"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="230"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="266"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="298"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="337"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4173" evidence="2">
        <location>
            <begin position="232"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="470" mass="53490" checksum="23C2145BEFD091CE" modified="2019-11-13" version="1">MKQIVILIAAVLFSLLFYGQSVGLNLALFAVLALVLLLFYNLKKFRDRGVLLHSVAYLLSAVLVFVHRSSLSVMANLLMFVSLVGAVSESQSSIYLKWLNGLYTSIAGFFHRNIDRQEASKASNWKQKADLPQLAKLIGIPIVFIILFVLLYRQGNPVFEGLIARINFDFINLQWLLFTLMGYYLFSNIAQPVLVEPATSADLSVSNNLLETANFSEASLKKEQQLGTTLLGLLNLLLLVYILTDIISINAMIVSKASELSIQVHNGINTLIASIIIAIIIILYFFRGNLNFYAHNRILKNLSFLWISLNVALIVLIAIKNQNYIGAFGLTYKRIGVYVYIFMTLIGLLTTFLKVLNLKNLAFLFRSNTQVAFMTLLLLSGVNWDRRITQYNLTQAQDFDMDYLIKLSNRNAILLYDLKDSVAISETQKRAIEKKYQYYIQELQQRNWQELNYDNFSLDLLKTESNSVFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZB37</accession>
    <name>A0A5C6ZB37_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000060">
        <property type="protein sequence ID" value="TXD86440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002577">
        <property type="entry name" value="HTH_HxlR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01638">
        <property type="entry name" value="HxlR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51118">
        <property type="entry name" value="HTH_HXLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH hxlR-type" evidence="1">
        <location>
            <begin position="12"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="115" mass="13178" checksum="7E03ED76728F88F7" modified="2019-11-13" version="1">MKSKALKITARCPIRTTTDLLSGKWKLLILFQLAPQSLRPSELKRVIPDISEKMLIQELKTLCDSGMVIRKNFGEVPPRVEYELTSIGRKIMPLIAEMRNFAIEYENEIISNTKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBB0</accession>
    <name>A0A5C6ZBB0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2975 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19935</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000052">
        <property type="protein sequence ID" value="TXD86551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021354">
        <property type="entry name" value="DUF2975"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11188">
        <property type="entry name" value="DUF2975"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="178" mass="20193" checksum="5CAA1B7639D34DDB" modified="2019-11-13" version="1">MSKRNNFIWKGIQVICWLIFFGYCIQTGALIFNYVFSLFKPIATHNLHLGLDLSELYLKSKSIYTLVFALTVAISALKAYLFFVVLKLFKTLNITKPFSENVSGIITKITYYTLSIGIISIIAQEVVSQLSDKGYNVGIVERYWNDGGAYLLMTAILFAITFIFKKGIELQNENDLTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBB1</accession>
    <name>A0A5C6ZBB1_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_18350</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000031">
        <property type="protein sequence ID" value="TXD87021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001842">
        <property type="entry name" value="Peptidase_M36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02128">
        <property type="entry name" value="Peptidase_M36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PA" evidence="2">
        <location>
            <begin position="314"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="231"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="607" mass="65478" checksum="D9C984603ED674E1" modified="2019-11-13" version="1">MLSSEGNSYVFSNGNVSKIDIPVTLNLTPLEDGNIRLTWDLSIQKLDNLHWWSVRVDAVSGEIINVADWIRTCDFGELDMKAANNHNNKTQEGFSMFKPSATFMDGSQYSVFALPIQSPNHGDRSLLVEPANATASPFGWHDTNALPGAEHTITRGNNVFASENRDITTATGHSPDGGANLNFNFELDLDEAPAVYEDASLTNLFYMNNAMHDIWYQYGFDEASGNFQQNNYGKGGSGNDPVFASGQDGQGLNNASFGTPPDGNVPGMTMYLWGESRFKELVTVNNGPLAGQYISLNPSTAIGNNITGAFLLPVTGDLIVVDDGTAAPTEGCNALVNAASVAGKIALIKRGSCSFVAKIQQAQNAGAIGVIVMNHNNPDNDPNYAPYVTMGGASTPAFTIPSVFVNYQDGLAMATALNNGQTVNVTLKDYNVYQLDGSLDNSIVAHEYGHGISNRLAGGRFSANCLTNPEQMGEGWSDWFALMITMNAGDTPENPRGIATYSSGQTNDGVGIREAHYSTDFNINNFTYAATNDDTVLGTNSQGQTVSWNEIPHNIGAVWATMLWDLNWAYIEKYGFDADLYNGTSGNNKVMQLVIEVLNFKPVTLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBC0</accession>
    <name>A0A5C6ZBC0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_18405</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000031">
        <property type="protein sequence ID" value="TXD87031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007492">
        <property type="entry name" value="LytTR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04397">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00850">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50930">
        <property type="entry name" value="HTH_LYTTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="3"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="HTH LytTR-type" evidence="3">
        <location>
            <begin position="145"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD87031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="245" mass="28447" checksum="9D1E82DC599B340B" modified="2019-11-13" version="1">MIKAVIVDDEPKAIQSLSWELSHFSKNVQIINTFTSPEEAIVYINKNTLDCLFLDIQMPTMDGFQFLERLSNKEMAVVITTAYDEFAIKALKHEAIDYLLKPIDSDDLEQTIEKITKFKLRSSSNTSKIEEVLESLTERFDNKKITINTDGRLLFLDIEDIIFVESDGNYSIIYTMDNKKIVITKKLKEVDALLPDHFFFRIHNSFIVNLTKIKEFVKNHGYVVMTSNHKIPVARQRKSEFLEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBI4</accession>
    <name>A0A5C6ZBI4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_14160</name>
        <name evidence="3" type="ORF">ESY86_19655</name>
        <name evidence="2" type="ORF">ESY86_20620</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000094">
        <property type="protein sequence ID" value="TXD86093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="VORO01000044">
        <property type="protein sequence ID" value="TXD86659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13683">
        <property type="entry name" value="rve_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="2"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="52" mass="6173" checksum="0A900C56E07CA3F5" modified="2019-11-13" version="1" fragment="single">TNRYRFASSEQLHACLVEYISWYNTKRIHSTLGYRTPLEMQLKLENLINKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBL7</accession>
    <name>A0A5C6ZBL7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CRTAC1 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_19540</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000042">
        <property type="protein sequence ID" value="TXD86713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.130">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013517">
        <property type="entry name" value="FG-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011519">
        <property type="entry name" value="UnbV_ASPIC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13517">
        <property type="entry name" value="FG-GAP_3"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07593">
        <property type="entry name" value="UnbV_ASPIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="SSF69318"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="UnbV_ASPIC" evidence="2">
        <location>
            <begin position="548"/>
            <end position="614"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1123" mass="125985" checksum="2952E93F63C124D4" modified="2019-11-13" version="1">MTFQFFYQNVSKLGLAVFIGFTIYACNSDKKESNKEEKVRQETLFTSMMPEQTGIDFVNTVVNQKNFNIFKYRNFYNGGGVAIGDINNDGLPDIYFTANMGPNKLFLNKGNFVFEDISGTAGVVGNKPWSTGVTMVDINQDGFLDIYVSNAGNMEGNNHDNDLYINNGDLTFTEKAKDYNLATSGFTTQTTFFDYDKDGDLDAYILNNSNIPVSSLGYAHQREKRAQDWENVPDIFRGVGDMLLRNDNGKFTDVSEEAGIYGSLIGFGLGVMVTDINKDLYPDIYISNDFYERDYLYINNQDGTFKEDIENWTSHLCLSAMGVDIADVNNDGLADIFVTDMLPEADQRTKSVMEFEGYNVFKLKQRKDFFQQYIQNTLQINNGNNTFSEIANFSGVAKTDWSWAGLLFDMDNDGFRDIFITNGINHDLTDLDFVDFFANEIIQNMALTGKKQAIDSIINKMPQKPQPNYAYKNNKDLTFTDETTNWGFEKPSFSNGAAYADLDNDGDLDLVVNNVNMQAFVYRNNSEKRSNTNYIKLNLEGIPSNKFAIGSTVNIYHKDKIMVQEQMPTRGFQSSMDHVMTIGLGDATQIDSIRIIWPNDQTQKLTNVKVNKLLNIKQNEATSVYKLSTVKKAKPFFEEIPTEFVSHKENSYSDFDHEGLISKMLSQEGPALAIADINNDGHEDIFIGGAKGTSGNIYLNKSNGKLMVSKVKALIDDADLEDTAAAFFDVDNDGDMDLMVGTGGNEVGQQSTYKIRLYLNDGKGNFAKDTRSIPFTQNNISVIVPYDYDADGDVDVFIGSRSVVGTYGINPDHLFLENKGDGTFRDATQKIAYDLKDAGMITDAQWVDIDGDGKKDLITVSDWGTPNIYKNTGQRLMKLSSNLDDLKGLWNAVEASDLDNDGDLDLILGNQGNNTLYKFNAEEPMKMFINDYDNNGTIEQIFTRHLNGGDYPLHMKKELTAQIVSLKKENLKASDYAKRSINELFPKIDMNTTIVKQTNISESVIAINEGNGNFTIKNLPTMVQLSCVCGITCMDVNDDGLMDIILGGNNFEFKPQFSRLDANYGSLLLNKGNNEFEWEDYSKSGFFVRNEIKHIAKFKDKSGTIYVIAAINDEIPKVFKINK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBS0</accession>
    <name>A0A5C6ZBS0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nucleotide sugar dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_16930</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000024">
        <property type="protein sequence ID" value="TXD87463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017476">
        <property type="entry name" value="UDP-Glc/GDP-Man"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014027">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036220">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014026">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001732">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028359">
        <property type="entry name" value="UDP_ManNAc/GlcNAc_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00984">
        <property type="entry name" value="UDPG_MGDP_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03720">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03721">
        <property type="entry name" value="UDPG_MGDP_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500136">
        <property type="entry name" value="UDP_ManNAc_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000124">
        <property type="entry name" value="UDPglc_GDPman_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00984">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52413">
        <property type="entry name" value="SSF52413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03026">
        <property type="entry name" value="NDP-sugDHase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDPG_MGDP_dh_C" evidence="4">
        <location>
            <begin position="325"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD87463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="431" mass="47090" checksum="42EF3BC3DBBDC8A3" modified="2019-11-13" version="1">MGSLGKKISVIGLGYVGLPLAVEFAKKFLVVGFDINEKRIAELQQGVDKTLEVSSEELKAVLVSDASAQKGLLVTHNAEDIADTQIYIVTVPTPTDAMKRPVFTPLIKSSETVGKVLSKGDIVIYESTVYPGVTEDICVPILEAQSGMVFNTDFFAGYSPERINPGDKVHTVTKILKVTSGSTPAIAEEVDQLYKSIITAGTHKAASIKVAEAAKVIENSQRDINIAFVNELSKIFRLLDIDTKAVLEAAGTKWNFIKFSPGLVGGHCIGVDPYYLAQKAIESGYDPEIILAGRKMNDSMGPYVATETVKMMIHKGARIKDSNVLVLGITFKENCPDIRNSRVIDIIEEFQSYNINVDVYDPWASSEAVKEEYGLDLISEAGQLKTEYDAIVLAVAHHQFLEMDLVSLKSNVAVIFDVKSLLPYHITDARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBU9</accession>
    <name>A0A5C6ZBU9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Na(+)-translocating NADH-quinone reductase subunit A</fullName>
            <shortName evidence="2">Na(+)-NQR subunit A</shortName>
            <shortName evidence="2">Na(+)-translocating NQR subunit A</shortName>
            <ecNumber evidence="2">7.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">NQR complex subunit A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">NQR-1 subunit A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">nqrA</name>
        <name evidence="4" type="ORF">ESY86_16525</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:47748"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="7.2.1.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NqrA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.1.1" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000023">
        <property type="protein sequence ID" value="TXD87499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016655">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00425">
        <property type="entry name" value="NqrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008703">
        <property type="entry name" value="NqrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022615">
        <property type="entry name" value="NqrA_C_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37839">
        <property type="entry name" value="PTHR37839"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05896">
        <property type="entry name" value="NQRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11973">
        <property type="entry name" value="NQRA_SLBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01936">
        <property type="entry name" value="nqrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0406">Ion transport</keyword>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0915">Sodium</keyword>
    <keyword evidence="2" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="2" id="KW-1278">Translocase</keyword>
    <keyword evidence="1 2" id="KW-0813">Transport</keyword>
    <keyword evidence="2" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="NQRA_SLBB" evidence="3">
        <location>
            <begin position="261"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD87499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="449" mass="49368" checksum="7B8240F900AD53A9" modified="2019-11-13" version="1">MSNDIKIKKGLDIKLQGEAEKVVEQATFSNFCTLRPEDFHSVTPKLVAKEGDMVMAGDVVFHDKSYDAVKFVSPVSGKVVEVLRGPKRRIDAIKILADKEQSHKDFGVFDSNANAETTKSHLLSSGCWPFIKQRPYDVIADPDSEPKAIFISGYDTAPLAADLDYTLSGKEAELQAAVSALAKLTPGKIHVGVKSNTSPLAGLEGVTVHKVSGPHPAGNVGTHINKINPVNKGETVWTINPADLVIMGELLLTGKFNAERMVALVGSSVQKPRYFKTLIGSEVSTMVYDNGVDKNGNDRIISGNVLTGKQVKPDGNLGYYSNLISVIPEGDDYEFFGWNKPVFDKVSTSRALTFSWMQPNKKYDLNTNTNGEHRAFVITGIYEDVFPLDIFPMQILKACMYEDLDEMEALGMYEVAPEDFALTEFVCVSKQPHQQIIRNGLDLMLKEIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBY7</accession>
    <name>A0A5C6ZBY7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_20230</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000061">
        <property type="protein sequence ID" value="TXD86425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="169" mass="19307" checksum="04109C142F6013F6" modified="2019-11-13" version="1">MKKLNLFIGIVIGILFFSCSSEDDNNNHSENDPIVGQWKIINETYFDLNGNQSFQQTPSDCLQESRETFSLNGAYNWTSFIEESNGDCVNIIQTVNNGQWELLANGNYKISGTVIYTDADSFNLNLEFDDTNFSNNSMNLALKATIQEFDESGNIEDEYIRLFEYEKIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCC8</accession>
    <name>A0A5C6ZCC8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000047">
        <property type="protein sequence ID" value="TXD86603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="179" mass="21365" checksum="D6F6D319AA1BEB60" modified="2019-11-13" version="1">MNRILQPKIITIILFSLLSFVILTLYVWHFSFTWEFVFGVVFYIIFLLAILLIGILISMKIDSKKKSKLKYYFIISFIQLLIIWLLSIPVSNWQIKYSKENGMNIVELVEKYKISYGTYPKSLSEIEQKTNSNIPKWTALGTKYNYEFFDNGNFSVGFKSYYGYDLYYDKRNKKWTSYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCJ0</accession>
    <name>A0A5C6ZCJ0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Biopolymer transporter ExbD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_15675</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ExbD/TolR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003400">
        <property type="entry name" value="ExbD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30558">
        <property type="entry name" value="PTHR30558"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02472">
        <property type="entry name" value="ExbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD87751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="131" mass="14715" checksum="42D7084B406CFBDD" modified="2019-11-13" version="1">MKLRGRNKVTPEFNMSSMTDIVFLLLIFFMLASTLVTTNAIDIVLPKASGKTENKQSVAVSIKKDLTYYIDQKRVGESVLETQLKDMLASQEEPTIVLRAEKSVPIENVVKVMDIANRNKFKVILAVKPND</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCK7</accession>
    <name>A0A5C6ZCK7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_20305</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000064">
        <property type="protein sequence ID" value="TXD86395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="140" mass="16262" checksum="54DC5035DF97EFA0" modified="2019-11-13" version="1">MKTLIFFFSILLFTSCNNDDDNSTEPEQDQHETIGEWHLITYECCLFESYEYTDEITWVINPDNTIDIAIDYGTYVSSNMPFNSSGNYTYNINENEDRDEIIIDGTTYYYLMSNTGTQLIIEDEIGFSADGLLLLFEKIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCL3</accession>
    <name>A0A5C6ZCL3_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3 4">Single-stranded DNA-binding protein</fullName>
            <shortName evidence="2">SSB</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ssb</name>
        <name evidence="5" type="ORF">ESY86_15835</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04496">
        <property type="entry name" value="SSB_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00984">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000424">
        <property type="entry name" value="Primosome_PriB/ssb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011344">
        <property type="entry name" value="ssDNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10302">
        <property type="entry name" value="PTHR10302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00436">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002070">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00621">
        <property type="entry name" value="ssb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50935">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR002070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD87781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="114" mass="12570" checksum="80DBF7471D7C0E0F" modified="2019-11-13" version="1">MSSIKNHVQLIGNVGQDPTITNLESGKKVARFSVATNENYKDSKGEKQTNTNWHTVVAWGKTAEIVENYVGKGKEVGIVGKLKTRTYTTDDGNQRYVTEVVADEILLLGSKDNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD94</accession>
    <name>A0A5C6ZD94_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transcription-repair-coupling factor</fullName>
            <shortName evidence="8">TRCF</shortName>
            <ecNumber evidence="8">3.6.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">mfd</name>
        <name evidence="11" type="ORF">ESY86_19520</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">In the C-terminal section; belongs to the helicase family. RecG subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">In the N-terminal section; belongs to the UvrB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="8"/>
    <dbReference type="EMBL" id="VORO01000041">
        <property type="protein sequence ID" value="TXD86730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000716">
        <property type="term" value="P:transcription-coupled nucleotide-excision repair, DNA damage recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00969">
        <property type="entry name" value="TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036101">
        <property type="entry name" value="CarD-like/TRCF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003711">
        <property type="entry name" value="CarD-like/TRCF_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004576">
        <property type="entry name" value="Mfd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037235">
        <property type="entry name" value="TRCF-like_C_D7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005118">
        <property type="entry name" value="TRCF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041471">
        <property type="entry name" value="UvrB_inter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02559">
        <property type="entry name" value="CarD_CdnL_TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03461">
        <property type="entry name" value="TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17757">
        <property type="entry name" value="UvrB_inter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01058">
        <property type="entry name" value="CarD_TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00982">
        <property type="entry name" value="TRCF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141259">
        <property type="entry name" value="SSF141259"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143517">
        <property type="entry name" value="SSF143517"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00580">
        <property type="entry name" value="mfd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="583"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="753"/>
            <end position="919"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD86730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1124" mass="128388" checksum="A334D83B25713798" modified="2019-11-13" version="1">MSKLQLSKLYAQALQTQNLHSAIANSDDSQNDIPAKIHLKGLVGSSLSLVVSETFKASDKPFLLIFDDKEEAAFHLNDLETLLNQKDVLFYPGSYRRPYQIEETDNANVLLRAEVLNRINSRKKPALIVTYPDALFEKVVTRRELEKNTLKIKLGDQLSIDFVNEILFEYQFKRVDFVTEPGEFSVRGGIVDVFSFSHDEPYRIEFFGDEVDSIRTFDVQTQLSTEQIKKIGVIPNVANKFLQETRQSFLEYLSQKTVVFTKNTALLFDRIDDNFSKAREAFDKLSSEVKRTAPETLFCSSTLLKKQLLEFSIVEIGNSSLFSEEKIECNTSPQPSFNKQFNLLIEDLNAHHDQGYTNYIACASEQQAKRFHDIFDDATAAHHMSMENGKHYQTIVLSLYQGFVDHIQKITCYTDHQIFERYHKFHLKNGYAKKQAITLKELTNLDIGDYVTHIDHGIGKFGGLQKIDVEGKKQEAIKLIYGERDILYLSIHSLHKITKFNGKDGKPPKIYKLGSKAWKVLKQKTKSRVKEIAFNLIQVYAKRKLEKGFQYMPDSSLQHELEASFIYEDTPDQTASTADIKADMESERPMDRLVCGDVGFGKTEVAIRAAFKAVDNGKQVAVLVPTTILAYQHSRTFAERLKEFPVTVDYLNRFRTAKEKRETLEKLEKGHVDILIGTHQLVNKNVKFKDLGLLIVDEEQKFGVAVKEKLKTLKDNVDVLTLTATPIPRTLQFSLMAARDLSVITTPPPNRYPIESHVVRFSEETIRDAINYEIQRGGQIFFIHNRIENIKEVAGLIQRLVPDAKIGIGHGQMEGKRLEQLMLAFINGEFDVLVSTTIVESGLDVPNANTIFINHANNFGLSDLHQMRGRVGRSNKKAFCYFITPDFSSMTNDARKRITALEQFTELGSGFNIAMKDLEIRGAGDLLGGEQSGFISDIGFDTYQKILNEAIEELKENEFKDLYEDDGSEKEYVKDLSIDTDFELLFPDDYVNNIAERLNLYTKLNTLKTEEELKTFASEIIDRFGEMPVQVVDLLNSVRVKWIATRIGLEKIVMKKGRFIGYFINDQKSGFYQSDHFSKVLKYVQSHPQECKMKEKQTRNGLRLLLTFENIKSVKQALSKLQGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDD0</accession>
    <name>A0A5C6ZDD0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sensor histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17905</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000028">
        <property type="protein sequence ID" value="TXD87189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="1">
        <location>
            <begin position="547"/>
            <end position="777"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="781" mass="87778" checksum="B6B165450DC313E1" modified="2019-11-13" version="1">MSKTEEIQAKLLLAIQSVPPNLDDILFLSRELAKQDPHNQRFYIDAKTLIHLGRDSIKDHSTALLELVKNSYDADATKVDIEIFSETKDLIRVADNGFGMTSDELKNSWLRIGYSGKRVSTKSKLGRRKTGEKGIGRISTDRLGSILELRTKSKNDKLTGLKVNWDDFDVEGKSLSDIRVEIFEPSEISLPVKDGKPSATGTEIIIERQRQPWSKLNIENLQQELSALTPPFEDVQDFKISLVNDIYPLPSEEINSNYLNAAEIKIEAYYPGTGSEIIYTYWDKYNGKEVIEKIEWSNLLTRTGMDTSNLIDNQIRSGSMTIKLYFFLREGASVKDLDFNLTKLREFLDNNAGIKIYRDRIVVKPYGFPSSQFGYDWLGLADRKAKDPAGISRSKNYSVTPNQLVGAVFIARDSNIELADSAAREGLVESEAFYDLKSLVMGTVNMLESYRTKLIPKINEAKRKSRTKESRTERIIKALNSVEKDLYSINLEIQNNTDIKTHLKERVQKNINQLSGTTDKVEKTITELLNWNRTLSGLATIGISSAVFGHETEGSITQLKGSVMAAKLALSRKDPNVEEALNEIAKAVTSSTKVAAWGAYALTRVQREKRSKKDVNIGKIINSVVNELEPAYRAASITLNMNLKDVYTYTYQMDIETLLINLMTNAYTAATNKSGKRVINIQLIEEDLKESKRLVENGYALIISDSGPGVSKEYEHRLFEPLFSTKVNPSMGSKSIGTGLGLTVVNSIVQDLNGKITFDKDPELKGARFKIWLPKERKTII</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDG0</accession>
    <name>A0A5C6ZDG0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transcriptional repressor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19610</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000044">
        <property type="protein sequence ID" value="TXD86650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002481">
        <property type="entry name" value="FUR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33202">
        <property type="entry name" value="PTHR33202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01475">
        <property type="entry name" value="FUR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="135" mass="15408" checksum="A144A986478A2949" modified="2019-11-13" version="1">MKQQKLKVENALAHVHLKKTPVRITLLSHFMTVDCAQSYFDIEKAFNKKFDKSTVYRTLGSFEETGLLHRIDDASGITKYAFGRFGDGHNHYHFICNHCKNTYCIENDEAELIPLPKGFQSKHISTIINGICANC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDL9</accession>
    <name>A0A5C6ZDL9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PAS domain S-box protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_17670</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000027">
        <property type="protein sequence ID" value="TXD87263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016772">
        <property type="term" value="F:transferase activity, transferring phosphorus-containing groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAC" evidence="2">
        <location>
            <begin position="221"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="1">
        <location>
            <begin position="291"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="503" mass="57462" checksum="4D209D88C95283AB" modified="2019-11-13" version="1">MDHIEKRVLTSKKPSIANDELKFLSSIQNSIAMGSWEINLQEMDLKWSDMTKKIHEVSSDYKPDFEEAIHFFPEGKYRNRLLEVFDRAVNLGENYDVELQLKSAKNNIKWVRSIGYPIFENNKCIKVHGVFQDITDRTNRIADILLKEKQINSTWHHSPNGMAIIGLDAKLKSANKSLCQFLEYTENELIGLNFSHLTYHEDKEVATAQVLEMIEGTRDHFEAEKRYISKTGKLVPCLVNVTMLRDNNNVPMHFIANLTNISKIKKAEQDIKNLLDTTESQNLRLLNFAHIVSHNLRSHSGNLQMLLDLVQDEIPESTDNDYFPLINEAVNNLSETIFNLNEISNINTRVNNDIASLNLLHFAEKAISNNRAKILETNAVIVLDIDKSIEVLAIPAYLDSILLNFVTNAIKYRQPNVALLIKLKAQKTDEHVQLDIEDNGLGINLNLHKDKLFGLYKTFHKHDDARGLGLFITKNQIDAIGAKVTVTSTVNEGTTFSLFFRYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDQ5</accession>
    <name>A0A5C6ZDQ5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">YkgJ family cysteine cluster protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19310</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000039">
        <property type="protein sequence ID" value="TXD86774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005358">
        <property type="entry name" value="Puta_zinc/iron-chelating_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03692">
        <property type="entry name" value="CxxCxxCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="164" mass="19075" checksum="6BD5FE6A535FCF2A" modified="2019-11-13" version="1">MEPNIKQLPQLAKDKHKETKGFFAKLKKKPPKHLDYLMQELHEKEFERTDCLDCANCCKTTGPLFTDKDVARIAKHFKMKPQQFIDSYLRVDEDNDFVLQSVPCTFLGADNYCSIYEVRPKACSEFPHTDRKKFQQISNLTLKNVAICPAAYNIVEAMKQRINQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEJ7</accession>
    <name>A0A5C6ZEJ7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AhpC/TSA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD88001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025380">
        <property type="entry name" value="DUF4369"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013740">
        <property type="entry name" value="Redoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14289">
        <property type="entry name" value="DUF4369"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08534">
        <property type="entry name" value="Redoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="202"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="345" mass="39762" checksum="4833384EC159D9BD" modified="2019-11-13" version="1">MKRIFLVLLVISITFSCKKDGEITKRETFDLTVSAKNFLDSTKVYLYNRDIDKNIDSAFVINERFKFSGKVDLPSLCYLEFYDKNKKHIEPYKFFFLENENISISGDYSDFINAKVTGSNQTDLYSKYDSISINSDKRYKVDKEIDFLFSNANNQMTLNELLYKKKEVSKDSLLLFHKKLDSINSNSPKGQELLAYAKTVDIKPGDKFRDIVGKDLNGKQHKLSDYKGKVILLDFWAAGCYPCRLQNKKEFPELVKKYSNDDFIIVSYSLDTDEKSWRKSSQDDKINWLSISDLKGMKGENVKNYAVTAIPNSFLIDQNGVIVKSFVGFSEGANIIEKEIDQLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEN0</accession>
    <name>A0A5C6ZEN0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-6 DNA methylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17920</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000028">
        <property type="protein sequence ID" value="TXD87192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003356">
        <property type="entry name" value="DNA_methylase_A-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02384">
        <property type="entry name" value="N6_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N6_Mtase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="530" mass="61471" checksum="09078CAA4D97CC6D" modified="2019-11-13" version="1">MNKKNSGSYYTPIRLANFIADYCLENFDQNNISILEPSVGDGNFAAAISNNIQLNRFQNTTLTIVERELDELNKAIDRCNPQVNLNSIPSDYLDFHNSDDNFYSLIIGNPPYIKSTLLSDEQKHLCKSIHIDSGLKDKKINNIWTAFLVSAIQKIENNGVIAFVLPLELLQVKFSEEIRDLLKSSFERLEVFMFDELQFQECKGQDTVLIVGYNQHQVQGTYYTTVGSIEELENRSFTLMQNISVSESNTKWTHHFLSPDEHHFLENLKSKLDLTTHYVDNKAGIVTAANDYFIVNDEVVTKNRLRFYSKPIVQKGFYVNGSVTFEDEDFNKLVEDDKPAYLLDFNRANPDKLSKSVLCYLDIGTERKLETRFKCRQRKHWYQVPNIAKQSEAFFFKRAHEYPKLLKNNAEAYVTDSAYMVESKEGYNIENIIFSFYNSLTLAFAELEGRYYGGGVLEITPNEFRSLPLPYEVVQDFEQYRNDFKNKKSIEDILVKYNFKILNSALGLNIEEIERIEAIRKKLVAKRMKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEU5</accession>
    <name>A0A5C6ZEU5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fasciclin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_12215</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02469">
        <property type="entry name" value="Fasciclin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00554">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="SSF82153"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50213">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023029111" evidence="1">
        <location>
            <begin position="25"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="2">
        <location>
            <begin position="35"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="2">
        <location>
            <begin position="182"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="331" mass="33901" checksum="9C8B5F98F0E544BD" modified="2019-11-13" version="1">MKIISKTLKFLPLLLVVLAFQACSDDDDAPIIVQERDIVDTAISTSQLTSLVAALQAADGDLVGLLKGSGPFTVLAPNNAAFTAFLADNNFASLGDVPTDVLAMVLKNHVIAGDIEAEDLQNLQANGTNYANTSATGPGGNELSIYFNTSNGVKFNGISSVETANIDATNGTIHIVDAVIGLPTVVTFATADPNFSTLVTALTTLTPDNDYVATLSTPNGTSPAPFTVFAPTNTAFDELLVELEVAGFGDIPTATLIAALNSHVVAGANVQASGLSDGLLIDTLGADLTANITGGATLTDPNGRVSNIVATNVQAVNGVIHAIDKVVLPQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEY9</accession>
    <name>A0A5C6ZEY9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GntR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_17240</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CvfB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000026">
        <property type="protein sequence ID" value="TXD87307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014464">
        <property type="entry name" value="CvfB_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039566">
        <property type="entry name" value="CvfB_S1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040764">
        <property type="entry name" value="CvfB_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37296">
        <property type="entry name" value="PTHR37296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17783">
        <property type="entry name" value="CvfB_WH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13509">
        <property type="entry name" value="S1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF012524">
        <property type="entry name" value="YitL_S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1_2" evidence="2">
        <location>
            <begin position="4"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="CvfB_WH" evidence="3">
        <location>
            <begin position="219"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR012524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD87307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="278" mass="32015" checksum="69F4DB00F53D5BAF" modified="2019-11-13" version="1">MIRIGDYNTLEIIRESEQGLYLGDGEEKEILLPNRYVPEAFKIWDKIEVFVYLDNEERPVAVTDEPYIIRDDFAMLRCNQVTAHGAFLDWGLVKELFCPFKEQAFKMKAGGWYLVHCYLDDESNRLVASSKTNRFLDNATLTVQEFDEVDLIVSHPSDMGMNVIVNNQHHGLIFNDNIFKDLSVGDRLKGYVKKIRPDNKLDIVLGKIGYRKIEPNADLIVEHLENSRDGFIPLNDKSDPNAIKNELQMSKKTFKKAIGTLYKQRVISIDNDGIRLIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF23</accession>
    <name>A0A5C6ZF23_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17455</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000026">
        <property type="protein sequence ID" value="TXD87347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="132" mass="15379" checksum="62889C22C4FD13D4" modified="2019-11-13" version="1">MKTLEIKKIETSILLAICLVLFLSIKAVIPNFLSVFVILLMSFYFFPVKLILNKVKDFNKQNILSDIIISTSLILLIVGIYLDSDFMSIIFTFINFIFLIYIVFNGQNLSEYRKIILNHLLVIFLLQMIQYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-02-10" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFB1</accession>
    <name>A0A5C6ZFB1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">BamA/TamA family outer membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_14805</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000184">
        <property type="entry name" value="Bac_surfAg_D15"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01103">
        <property type="entry name" value="Omp85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022942217" evidence="1">
        <location>
            <begin position="24"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="domain" description="Omp85" evidence="2">
        <location>
            <begin position="288"/>
            <end position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="563" mass="64652" checksum="CCC7B3FB35AC7A0C" modified="2019-11-13" version="1">MTKRTLLYFSILIFHFSAEQALAQNLKLSILGKTEAETKTIDSLGYASRFEDLQSLKLELANFSKKIETIGYIDQKLLSYFKENDSLYLAQFSLKKRFSQVRIYNKELVPRSIFKMIDTKVENDHFTVPIEELELTLQLINAEIANEGSPFLTLTLEQINKNDDFTLSARLTASNTSARTIDNIIVKGYEKFPESYLKHFLKLKTGQDFNLKKIKLKSASLNNLMFANVIRDPEVLFTQDSTLLYMYIEKNKSNTFDGFLGFGTNENTNKIEFDGYLRLNLTNNLNYGESLKLLYKSDEIEQKTFDLSLQMPFLFGSPLGATVKLNIFKRDSTFVTVEQSARINYQFDPKNSVSLGVKAINSTDLLDLNTSIINDYRSNSYFANYQYTQQRQKDPLFPIDALFDFTAGTGSRIFDQNRDAQNHFALETYKIFDFNATNSFFSRLTSEYFTSNTFLENELFRFGGINSIRGFEENSLLANLYAVLNTEYRYRLNSTLYVHSVVDAAYFENQLIDQKGKLFGFGFGFGLLTKAGLFKFNYSSGKTENQSFSLTNSKIHLSLTALF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFN3</accession>
    <name>A0A5C6ZFN3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Prohibitin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_10435</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03401">
        <property type="entry name" value="SPFH_prohibitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000163">
        <property type="entry name" value="Prohibitin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23222">
        <property type="entry name" value="PTHR23222"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00679">
        <property type="entry name" value="PROHIBITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="PHB" evidence="2">
        <location>
            <begin position="24"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="270" mass="29779" checksum="9717685DC08492BB" modified="2019-11-13" version="1">MEKLPKGGAFALILIIALVIIIFKSVVTIDSGHAGVLYQLSGGVDPEKDPLQEGLNFVAPWNSVIDYEVRQQALSEKMSALSSNGLDIALDATVLFQPDYENLSRLHKEKGKEYVSRVLQPAIRSAARSVVGRYTPEQLYSSKRDAIQDEIFEETNKIVSSQYIQLNDILIRDVTLPPTIKQAIERKLKQEQESLEYEFRLVTADKEAQKVRIEAQGKADANKILSASLTDKILQDKGIDATMKLAESPNSKVIVIGSGDSGLPIILGNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFT8</accession>
    <name>A0A5C6ZFT8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Crp/Fnr family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10830</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="1">
        <location>
            <begin position="30"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="191" mass="22248" checksum="36D210A7C7624143" modified="2019-11-13" version="1">MLKSIVTHIKQYVKPSAEELNQFTALLQEVSVAKRKFLLLPGTHVKHEYFVFKGCLKAYYMDDKGNKHVVQFAIENWWIGDFDAFYNQVSSKLHIEAIEDSQLLAINYDDLQALYDEAPVFERYFRLLVTSAFVAQRKRILSALEKDAKARYLEFRLSYPSIETRVPNYHIANYLGVSAESLSRIRRSLKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFW4</accession>
    <name>A0A5C6ZFW4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutamine synthetase type III</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_16640</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glutamine synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000023">
        <property type="protein sequence ID" value="TXD87521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004356">
        <property type="term" value="F:glutamate-ammonia ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040577">
        <property type="entry name" value="Gln-synt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008146">
        <property type="entry name" value="Gln_synth_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027303">
        <property type="entry name" value="Gln_synth_gly_rich_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022147">
        <property type="entry name" value="GSIII_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00120">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18318">
        <property type="entry name" value="Gln-synt_C-ter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12437">
        <property type="entry name" value="GSIII_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01230">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00181">
        <property type="entry name" value="GLNA_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gln-synt_C" evidence="2">
        <location>
            <begin position="186"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="728" mass="82065" checksum="F04F887B5EB17F04" modified="2019-11-13" version="1">MSTLRFHALKQIYNLKPVLIEEKVRRSEIFGANVFKESTMRQYLTKEAYDSVIDANVNGSKIDRVVADHISTGMKEWAISKGATHYTHWFQPLTGATAEKHDAFFETIGGGLAIEKFGGGQLVQQEPDASSFPNGGIRNTFEARGYTAWDPTSPAFIVGTTLCIPTVFVSYTGEALDFKTPLLRALQAVDSASVAVCKYFDKNVKRVNASLGWEQEYFLIDSGLAMSRPDIVLTGRTLLGHSPAKGQQLDDHYFGTIPNRALDYMRDLETECMLLGIPVKTRHNEVAPNQFELAPIYDEANLAVDHNSLLMDIMDRIAERHKLKVLFHEKPFAGVNGSGKHNNWSLTTNTGVNLLGPGKTPMSNLQFLTFFINTIKAVHDNEELLRAAIASAGNDHRLGANEAPPAIISVFIGEQLTKVLDELENVTDGKLSPEEKTDLKLNVVGKIPDVLLDNTDRNRTSPFAFTGNKFEFRAVGSQANCANPMTVLNAIVAKQLIDFKKQVDALIKKDDMKKDDAIFNVLREYIKKSRNILFEGNGYGEEWEKEAKKRGLSNNKTTPEALKVKKSDKTVKLYEDLKVMNRIETIARYEIEMDEYALRIQIEGRVLGDIARNHVVPTAVRYQNILIENVKGLKDIYGDDFKNLASEQMNLIEEISGHIESINSNVTKMTDERRTANKIEDIEEKADSYCHKVKPYFEKIRYNCDKLELLVDDELWPLTKYRELLFTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG33</accession>
    <name>A0A5C6ZG33_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">UpxY family transcription antiterminator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_09745</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006645">
        <property type="entry name" value="NGN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036735">
        <property type="entry name" value="NGN_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043425">
        <property type="entry name" value="NusG-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30265">
        <property type="entry name" value="PTHR30265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02357">
        <property type="entry name" value="NusG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82679">
        <property type="entry name" value="SSF82679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0889">Transcription antitermination</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="NGN" evidence="4">
        <location>
            <begin position="5"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD89048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="156" mass="17826" checksum="F42AF2128057393B" modified="2019-11-13" version="1">MQQLNWYVIITKPRSERKVADRLSAIGIDVYCPIKTEMRQWSDRKKKVEVPVLPSMVLVKLADKDRNRVFEVTGVVRYLFWLGEPAVVREEEIDVLKKAMDSGLNIVEVDTIKVGDMIEIEGLGSVKKEKGKVKYVSGNRCWVVLESLGYVVTLDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG36</accession>
    <name>A0A5C6ZG36_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA threonylcarbamoyladenosine biosynthesis protein TsaE</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaE</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">tsaE</name>
        <name evidence="5" type="ORF">ESY86_10370</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TsaE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003442">
        <property type="entry name" value="T6A_TsaE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02367">
        <property type="entry name" value="TsaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00150">
        <property type="entry name" value="T6A_YjeE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00032441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD88895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="140" mass="15980" checksum="3634EE3BB5A1D70C" modified="2019-11-13" version="1">MSYDLSQVDAIAKQVLEQCNCKVILFQGEIGAGKTTLVKALVGRLGSVDEVSSPTFSIVNEYLLEDGAVFHFDLYRINSEDELLDLGFEDYINTNNWIFIEWPEKAFNLLPESWESILIKHINQDERALIMSHNLLKTQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG95</accession>
    <name>A0A5C6ZG95_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_10085</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="26"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="112"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="152"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="179"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="224"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="260"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="291"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="315"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="351"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="382"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="25"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD89108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="408" mass="45572" checksum="F8375C92A9A3FFD8" modified="2019-11-13" version="1">MLLLNFIQKKLLIPYYKAFTGLSVEVWWLALITFINRAGTMVIPFLSLYLTKNLHFTLENVGWIMSAFGLGSVAGSWLGGKLTDRIGYYKVMVYSLFLTGFLFIGLQFLNTLYAFCFGIFVVMLAADMFRPAMFVALNAYSKPENKTRSLTLIRLAINLGFSAGPAVGGLIITGLSYGGLFWVDGITCILATVVLLKTLNPKKAKVTDNYKSAIPESAYKDRSFLIFLVAMVLFGIVFLQYFSTVPIYYDNEIGLSEFEIGLLLGLNGFVIFLFEMPLIKWLETTKYTHTGLMLFGAVLVGASFLVLNISPWVGMLIFGMLLMSIGEMITFPFSNAFALNRAKKGKQGEYMALYSISFSVAHIFGHNAGLQLIDRIKFENTWYVMAVLSALCVVLLLFLKKQMNTKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGJ3</accession>
    <name>A0A5C6ZGJ3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidylprolyl isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_09265</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000297">
        <property type="entry name" value="PPIase_PpiC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027304">
        <property type="entry name" value="Trigger_fact/SurA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13145">
        <property type="entry name" value="Rotamase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109998">
        <property type="entry name" value="SSF109998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50198">
        <property type="entry name" value="PPIC_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PpiC" evidence="2">
        <location>
            <begin position="358"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="719" mass="79507" checksum="C597C19C749C4BE8" modified="2019-11-13" version="1">MAVLNKIRQRSLFLILIIALALFSFVLTDLFRNSDALFGDSQDVVATVNGNKIDRNQFMGQVESLQQQMGPQATSTQVMNRVYDQEVRRAVMSTQFDELGMSVEEDEMRDLLKQNFTSYPEFQNEAGLFDENKLNEFVANLKAIAPEPSILGNFRITYNDWVNNETNIAIGAQERSYYNMVKAGVNATLNEAEIEHNLENSNRNLKYVQVPYSSINDSLVAVSKSDIKDYIEKNKKKYEVEASRDIAFVQFNEEPSLEDEKNLSSEFDMYSNGKVLFENGKNDTIQAFAKVEDSNIENYVNFTANSEEKYTDSFIKKSGLPDVVADTLYKLNVGDVYGPYKDDGMMKLTKIVAEKQMPDSAKVRHILIPFIGASSAGPDVTRSEAQAKATADSVLTVVKAYPSKFPELVTALSSDQGSVENGGEYDYHPSTQMVKPFSDFEFQNKTGDIDVVQTQFGFHVIEILGQKGESRAVKTATIAKKVEPSTETIDNVFTEASKFEMALQEADLQDAAKERDMAIKPVNGIKVLDENIPGLGSQRPIVRWAFEEGTSVGDYKRFSIPGGGYAVVQVTNKTKKGLMNPENASASALSEIRKGKKAKMIREKISGTTLEEVAKTPSAKTNTASAVNMKNPTLAGAGLEPKVVGVAFGLKEGETSGLIDGNSGVYVVSVLKIEPTSELENYQGVANRLSRTRANAAQSKVYNALKETAEIDDNRARFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGM4</accession>
    <name>A0A5C6ZGM4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Phosphatidylserine decarboxylase proenzyme</fullName>
            <ecNumber evidence="5">4.1.1.65</ecNumber>
        </recommendedName>
        <component>
            <recommendedName>
                <fullName evidence="5">Phosphatidylserine decarboxylase alpha chain</fullName>
            </recommendedName>
        </component>
        <component>
            <recommendedName>
                <fullName evidence="5">Phosphatidylserine decarboxylase beta chain</fullName>
            </recommendedName>
        </component>
    </protein>
    <gene>
        <name evidence="5" type="primary">psd</name>
        <name evidence="7" type="ORF">ESY86_15085</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a 1,2-diacyl-sn-glycero-3-phospho-L-serine + H(+) = a 1,2-diacyl-sn-glycero-3-phosphoethanolamine + CO2</text>
            <dbReference type="Rhea" id="RHEA:20828"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57262"/>
            <dbReference type="ChEBI" id="CHEBI:64612"/>
            <dbReference type="EC" id="4.1.1.65"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </cofactor>
        <text evidence="5">Binds 1 pyruvoyl group covalently per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterodimer of a large membrane-associated beta subunit and a small pyruvoyl-containing alpha subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="5">Is synthesized initially as an inactive proenzyme. Formation of the active enzyme involves a self-maturation process in which the active site pyruvoyl group is generated from an internal serine residue via an autocatalytic post-translational modification. Two non-identical subunits are generated from the proenzyme in this reaction, and the pyruvate is formed at the N-terminus of the alpha chain, which is derived from the carboxyl end of the proenzyme. The post-translation cleavage follows an unusual pathway, termed non-hydrolytic serinolysis, in which the side chain hydroxyl group of the serine supplies its oxygen atom to form the C-terminus of the beta chain, while the remainder of the serine residue undergoes an oxidative deamination to produce ammonia and the pyruvoyl prosthetic group on the alpha chain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.65" evidence="5"/>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00558">
        <property type="reaction ID" value="UER00616"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004609">
        <property type="term" value="F:phosphatidylserine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006646">
        <property type="term" value="P:phosphatidylethanolamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00664">
        <property type="entry name" value="PS_decarb_PSD_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003817">
        <property type="entry name" value="PS_Dcarbxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033175">
        <property type="entry name" value="PSD-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35809">
        <property type="entry name" value="PTHR35809"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02666">
        <property type="entry name" value="PS_Dcarbxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00164">
        <property type="entry name" value="PS_decarb_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="1 5" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="3 5 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="5" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="4 5" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 5" id="KW-0865">Zymogen</keyword>
    <feature type="chain" id="PRO_5023549001" description="Phosphatidylserine decarboxylase beta chain" evidence="5">
        <location>
            <begin position="1"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023549000" description="Phosphatidylserine decarboxylase alpha chain" evidence="5">
        <location>
            <begin position="186"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate; via pyruvic acid" evidence="5">
        <location>
            <position position="186"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage (non-hydrolytic); by autocatalysis" evidence="5">
        <location>
            <begin position="185"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="modified residue" description="Pyruvic acid (Ser); by autocatalysis" evidence="5">
        <location>
            <position position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD87992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="218" mass="24661" checksum="BC4B610EC73EFC1F" modified="2019-11-13" version="1">MFHKEGYKIIVITFAIVVAAVLLIDTFVSLAWLRMTLIVCTTLLLILILQFFRNPKRQTILGEHTAMSPVDGKVVVIEEVFEKEFFKDKRIQISVFMSPINVHVTRFPISGKVIYSEYHPGKFLVAWHPKSSEENERTTVVVENDSFGKVLYRQIAGAMAKRIVNYATLEEEAIQGADSGFIKFGSRVDVFLPLDANIKVKLNQKVRGGESIIAELTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH85</accession>
    <name>A0A5C6ZH85_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyltransferase family 4 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_09820</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="371" mass="42917" checksum="FB5B4E50CCE64443" modified="2019-11-13" version="1">MKEHYKCTVVCFEHEDWSLEPSNAIKNRNPDVEFISIDRHKSLLQTLFAKVCHKVAIILNPFFKSNIKIAAFASNDKTPQLRLALKYSIKTEELHTVIAHNLGAFYPAMVLAKKSNAKLQLDIEDYHPGEELYFNKKYELQNRLLIMQETFNRAHTISYASEGIKLKSESVFKLKSHTKRAVIINAFRATDFSKPIEKNTSLNFVWFSQNISHKRGLEEVFRLAKEYKHINVHLIGKANEGFIEAMQPSENVIIHKPMHQDKLHRFLSTMDIGLALENKDGDGNRNICLTNKFLAYAQAGLYIFATDTFGQKHFLEQIGNQFGVIIETSLKATLMQFDEQVLDHKNKIDRWEVAKNFSWEKQSERLLVAMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHJ9</accession>
    <name>A0A5C6ZHJ9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">GHMP kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_09270</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="313" mass="35235" checksum="88FEB0D67575B826" modified="2019-11-13" version="1">MNQVPETYRSHGKLLLTGEYVVLDAAISLAVPTTFGQTLNVRPIAESRLLWKSFDEQKQVWFEASFEFHENSLKLASTSNETISNRLLQILLTAKHLNPDFLDSKSGFSVETHLEFPSNWGLGSSSTLINSIARWADVDAYKLLEDTFGGSGYDIACANAGSSLTYQLNSKMGRKISLVDFNPTFKSQLYFVHLNQKQNSREGIAQYRNNTSDKTASIERINAITREMVGCKTLNHFQKLMEEHEQIISDLIKMPPVKERLFADFNGAIKSLGAWGGDFVMVASETDPSAYFKSNGYHTMLRYSEMVTIDGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHQ0</accession>
    <name>A0A5C6ZHQ0_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">LHH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_09525</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026834">
        <property type="entry name" value="LHH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022385">
        <property type="entry name" value="Rhs_assc_core"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14411">
        <property type="entry name" value="LHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03696">
        <property type="entry name" value="Rhs_assc_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LHH" evidence="1">
        <location>
            <begin position="210"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="289" mass="32259" checksum="8CBD5157BFDF6EAA" modified="2019-11-13" version="1">MVMPNRRIVNGERYRYGYQGEYAETDEETGKPAFQLRMYDPRINRWLTPDPKGQFHSPYLAMGNNWVSFVDPDGGECCGGSGTDDDPFILDEVVITASGNASGVSSDSWTRYIPVYGSGVDAYDSFSRGDYWTGAMHTALAISDVFLVKSLVVGAGKFVVRQTAKKITTEVAEQATRKFWTNSVKFKNTKVFQRDDIIDVALKDARGRSNLQRMKKGIAPITPDGKSVNLHHMLQSEKGAIAEVTAAFHKSNHKILHINPNTIGSGIDRIKFAAFRTSYWKQRALDFAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHR6</accession>
    <name>A0A5C6ZHR6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Nucleotidyl transferase AbiEii/AbiGii toxin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_08880</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014942">
        <property type="entry name" value="AbiEii"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08843">
        <property type="entry name" value="AbiEii"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="369" mass="42476" checksum="BA689A0ED6411EFC" modified="2019-11-13" version="1">MIDNKSFKKEWLDSFRAKKEHKSINVTILEKMVHALSLLEHLKIAELDFVFKGVTSLVLLLKEGNRFSIDIDIISSVEREKLEEILEVVVANSHFKRHVLNERRSYKEGVPKAHYTFEFDSVYNPNVPGTILLDILFDSPHYPELIESAIEVSWLSVDGTTTTISTPSVNSICGDKLTAFAPETIGIPYYKQDQLFAMEICKQLFDLRKLFENITDIAIVKKSFSAFAKAELSYRSSDEDFNKRNITETEVLLDSINTCAINSKRERNSTAETKKKFEDLNRGIRSFGSAFLMTGHFRIEEAMAASARVAYLSAILLQPKVSEIEYYEGQDISELTIENEEWVYLNKLKRQPDKSIFYYWYKAVELLLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHT2</accession>
    <name>A0A5C6ZHT2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07775</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="52" mass="6053" checksum="584E87282F31C420" modified="2019-11-13" version="1">MGVTIWLGNELGKWLDFKFEKDFWAPTITLLAVFIAMYLVISQVLKMSKEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHT6</accession>
    <name>A0A5C6ZHT6_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RelA_SpoT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015969">
        <property type="term" value="P:guanosine tetraphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05399">
        <property type="entry name" value="NT_Rel-Spo_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007685">
        <property type="entry name" value="RelA_SpoT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04607">
        <property type="entry name" value="RelA_SpoT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00954">
        <property type="entry name" value="RelA_SpoT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RelA_SpoT" evidence="1">
        <location>
            <begin position="64"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="442" mass="52166" checksum="3B50BBDA8DD9DB76" modified="2019-11-13" version="1">MKYTGGDINRLGERLRECKDKHISDKDLDILQAHRLSFTEPLFKIFKELSQHKTRVERSAITAFRLKRISTIINKTIREPKMQLNRMWDVAGIRIIFGSEVAARKMLEIILDNYEVRGEIRDRFNNPKKIGYRAIHVYITDPVSGKVIEVQLRTHETHNWATLVEITDVLYETRLKEEGYNSNQEWGRFHQLVSSSKQLEQDDANFLYKTLDKYDFISRLAETFRKNSSVVKKQWQNVGPRDKYFLIELSSDSVPKLSSYNDYEKAEADYFEAYKKDEGALVVLTSIHKPSFEQISIAYANYILSYHKFIQDVQEILKELAIEKLEDKNFNEFRKIFRLYENIQANNIINILIERDDVIVRVEGKSIHLESNSKISTKKRKEIRKQINVGIQDLRKKHLLFIKEVNNVIDAGPSWAWRTKSFLKKHEKRVSKKLKSIDLKFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHX4</accession>
    <name>A0A5C6ZHX4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_08125</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="81" mass="9270" checksum="8F8233FB330B6105" modified="2019-11-13" version="1">MSSSKKRKEVLTDTDALKLLEFKAKKAGRNLKNDLEFVPLEESYAFEPSTSYKVMMDKMIEDHATGKTNHTSWEAIKKGMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI26</accession>
    <name>A0A5C6ZI26_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">S9 family peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_13515</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002469">
        <property type="entry name" value="Peptidase_S9B_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00930">
        <property type="entry name" value="DPPIV_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023009410" evidence="1">
        <location>
            <begin position="21"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="domain" description="DPPIV_N" evidence="3">
        <location>
            <begin position="111"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="DPPIV_N" evidence="3">
        <location>
            <begin position="235"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9" evidence="2">
        <location>
            <begin position="592"/>
            <end position="786"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="793" mass="90774" checksum="1D8778740142BCCC" modified="2019-11-13" version="1">MKKVLLFGILLFCGIMTMTAQKFNQSPLTIKEIMQGDQFIGNLPSNVQWAADGQTIYFDWNPDGVYSDSLYGYKLKDEKINKVDFDTEYGLPSSYGHFNANRTKRLYAKHGDIFLVDVASKATRPITRTNSYEGNPQFTANETKIAFEKGNNIFTWDIASGTTTQITDFTDTKENDEKKDSKDVWLYNDQLALFDVLRERKEKTDARDRLEKRNDSKQAFAIFIGDLSVANQQMSPDGNYVTYLTVKRATNKSTIAPHYITESGYTEDQQTRSKVGDTPDAYKMFIYDIVNRKVDTVSLENLEGLDYVPEYTKDYPDKPYKNDDRIGYISEPVWSADGKSALLDIASNDYKDRWIVLLNIKNGTVTNLDHQHDEAWIAGPGINSWGRSIGWMPNDQRIWFQSEETGYSQLYAMDLKTKTKEALTTGDFEIYEPKISNDKKHWYFTANKIHPGDRQFYSMPINGGAFNQLTTMTGKNEVSLSPDETKMAILYSYSNKPTELYLKENPMFSKKAAPAKQLTESTTEAFKKYKWRDPEIITFKAEDGAKVYARLYQPKPDVKNNAAVIFVHGAGYLQNAHKWWSSYFREYMFHNLLVDNGYTVFDIDYRGSAGYGRDWRTGIYRHMGGKDLSDQVDGANYLVNTHGIDKDKIGIYGGSYGGFITLMGMFNAADTFHAGAAIRSVGDWAAYNHGYTARILNTPVTDSLAYRRSSPIYFADGLKGDLLILHGLVDDNVHAQDMLRLSQRLIELEKHNWDMVLYPMEKHGFAEPSSWTDEYTRIYKLFQESLLQKIKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI40</accession>
    <name>A0A5C6ZI40_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DNA mismatch repair protein MutS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_11605</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS_family"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="PTHR11361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05192">
        <property type="entry name" value="MutS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="SSF48334"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="51"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="208"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="234"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="336"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_MISMATCH_REPAIR_2" evidence="5">
        <location>
            <begin position="431"/>
            <end position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD88611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="616" mass="70219" checksum="D401EDC3F883F448" modified="2019-11-13" version="1">MKIYRDNIKLNAAKLVRLSKLLNRYSWLRLFFFIISTAILISLFIFNLITAIFIAFPILILGFALVIKHHDKIAYLKKQTSFLKTINESEILREECDLEAFDPGDEFINQNHPYSADLDVFGQHSIFQLVNRTTTESGAMLLSEWLSDPAPNHEIYDRQEAIKELSQKLDWRQGFQASGMHFQNKNSDYFKLLAWVEKPATLLKNQHLYIAAAISLPVLLVLVSYFFYTNLNPSNTIIYVALLILVLLTNYMILRKLSPIAENIVETSTENLSTLKSYQTLIHKIESESFKSKKLNKLQSVFTKGNYSAYHEIKKLCSILEFSHQRPIKKIPIGGNYMYPLLNSVLLLDIYLIIGTEQWKSKNKTFLKSWAEVVSGFEVVNSFAGFCYSNPSYTFPELTEKNNYIHFESLGHPLIHSNERVCNDFNSEGAGNIVMITGSNMGGKSTFLRSVGLNLVLALAGAPCCATYAKLTNLNIFTSMRTQDNLMKGISSFYAELNRIEKMLKLIERNDNVYFLLDEMFKGTNSEDRHKGGYSLINQLNKLKTSGIIATHDIDLAKLSGSKNLVTNYSFNSEIKEHSMIFSYELDPGICTDFNASELMKKSGIEILSTISEERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI65</accession>
    <name>A0A5C6ZI65_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Glycerol-3-phosphate dehydrogenase</fullName>
            <ecNumber evidence="11">1.1.1.94</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">ESY86_08400</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>NADP(+) + sn-glycerol 3-phosphate = dihydroxyacetone phosphate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:11096"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.94"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.94" evidence="11"/>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009331">
        <property type="term" value="C:glycerol-3-phosphate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004367">
        <property type="term" value="F:glycerol-3-phosphate dehydrogenase [NAD+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046168">
        <property type="term" value="P:glycerol-3-phosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006168">
        <property type="entry name" value="G3P_DH_NAD-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006109">
        <property type="entry name" value="G3P_DH_NAD-dep_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011128">
        <property type="entry name" value="G3P_DH_NAD-dep_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07479">
        <property type="entry name" value="NAD_Gly3P_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01210">
        <property type="entry name" value="NAD_Gly3P_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000114">
        <property type="entry name" value="Glycerol-3-P_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00077">
        <property type="entry name" value="GPDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9 10" id="KW-0520">NAD</keyword>
    <keyword evidence="3 10 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD_Gly3P_dh_N" evidence="12">
        <location>
            <begin position="8"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="NAD_Gly3P_dh_C" evidence="13">
        <location>
            <begin position="183"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="258"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="194"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000114-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000114-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000114-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF07479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TXD89399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="333" mass="37292" checksum="2333D1C12EB645C6" modified="2019-11-13" version="1">MSKPLKYAVFGAGSWATAIVKMLCENLDTVGWYMRSVYTKEHLLKEQHNPSYLSSVEFKPSQLKLSNDINEMAKWADVLVFVIPSAFIHSELEKLTVDISKKTIVSAVKGIMPETGKLVGEHFNDDYKIPLEHIAVIAGPCHAEEVALERLSYLTIACTDQELGQTIANALSSDYINTRVSDDVIGIEYAVMLKNIYAIAAGIAHGLGYGDNFQSVLMSNAIREMKRFINKMHKMKRNINDSAYLGDLLVTGYSAFSRNRMFGNMVGKGYTVKSAQMEMNMVAEGYYATKSAKQLNIKNTKKTKLPIIDAVYAILYENKNPKKVFQKLTEKLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI81</accession>
    <name>A0A5C6ZI81_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_07430</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="77" mass="8798" checksum="6B53388C5E28D022" modified="2019-11-13" version="1">MRANSFNTGVAIEYLVLSKLYRLELEAYVSQGNKKSVDIRVIREDETPVSINVKSVRGYSSLVVNNVEPKHDHFIFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZID8</accession>
    <name>A0A5C6ZID8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_11945</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041700">
        <property type="entry name" value="OMP_b-brl_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14905">
        <property type="entry name" value="OMP_b-brl_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0675">Receptor</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022833095" evidence="1">
        <location>
            <begin position="21"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="2">
        <location>
            <begin position="142"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="OMP_b-brl_3" evidence="3">
        <location>
            <begin position="384"/>
            <end position="814"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="838" mass="95360" checksum="E6D5FA614CBE9591" modified="2019-11-13" version="1">MNQILSALSLMFLCSLSSLSAQNKINISGTVVDSQEKYPLEYATISFFNPNGSEAIEGGITDLEGKFNIEVVPGNYDLKIEYLSYKSKTYKNKSLTKAMDLGTVGLEVDMAALDQVTIVAERTTVEIKLDKKIYNIGSDLTTAGGTVSDALNNVPSVAVDVEGGISLRGNENVTILINGKPSAMAGFGDTNVLSQLPAEAIERVEVITSPSARYDAEGTAGILNIILRQKETLGFNGSITLNLGNPDLAGIAANLNYRTEKFNLFSNIGFRYDDAPRNSFSDANYFDRLIDGALRSPEYERIVEDQQVERNNRGYNANVGMEYFLSDKTSLTGSIFYRYKEDADISNNDSERFNNNAIVERTLRIERENQDENSYQLALNYMTKFNDEGHELTADFQFEEDRENQNTFINEDYLLTQDAATVPFQKEQIFATEDQKEFLFQADYVLPIGEDARFEAGYRGNFENEITDYRLEQEDLSDASFFVNDTITNLFDYEENVNAVYSQYGNKFGKFSFLLGLRLENTQLKGTIDSRLSDEELVEAFGFPIDTDFNNNYLGLFPTVNLIYNLGKDEDQEESLTLGYNRRINRPRSWYINPFPTRSSRTRVFQGNPNLNPAFSSAFDLGYLKRWDKFTWTTSVYYQYESDSFERVEENTGQRTTDGIDIIRTIPVNLSNNIRTGAELGILYNPKKWLRLNSSINFFQFKTEGEFNGIDYGAKNTSWFARFSGKVTLPGNIDWQTNAFYRGAEEGAQTRTEGLFSMDLAISKEVLKNKATVSLNVRDVFNSRIRNQFTTTEFFQRYSESQWRQRQVTLSLLYRFNMKKEKSRNGSRENGNEFEFEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIE7</accession>
    <name>A0A5C6ZIE7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">SulP family inorganic anion transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_13135</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Membrane</location>
            <topology evidence="1 5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008271">
        <property type="term" value="F:secondary active sulfate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001902">
        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="PTHR11814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="90"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="125"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="230"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="254"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="305"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="346"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="380"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="404"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="444"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="6">
        <location>
            <begin position="500"/>
            <end position="612"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD88451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="620" mass="66556" checksum="0AB48C1903695B9D" modified="2019-11-13" version="1">MKNLFSNVKGDAFGGITSGIVALPLALAFGVSSGLGPTAGLYGAIFISFFAALFGGTSTQISGPTAPMTAVSMVVIASIIAVNDGDVNKALPVILTVFLLAGLMQISLGALGLGKYIRYIPYPVVSGFMTAIGVIILVTQILPAIGYYPKEDMDYVNQYKPQAEETILKNILSEEAGEGILALEDFKETIGRAESISEADILKESKTLASNDASGVLGTLKVLPKAITQISWLELVLALGTIFIIYGFKRITTAVPSTLVSLVVMSGIAFGFKLNYRPIEEIPTGFPIPNLEIFTGFQLSSITPYIFTALTLALLGAIDSLLTSVVADNMTKTKHEPNKELVGQGIGNSIGAIFGGLPGAGATIRTVVNIKSGGKTKLSGMITGVVLLVILLALGPIASQIPAAVLAGILITVGIGVMDYKGLKAIPSLPKDIKIGPVKLSSEVLAMLVVLILSTFWNLVYAVGIGLVIASLMFMKKIGDLTGKRSDVKSLKEEVWKDEMDFPEKLKEEVFIKHVKGPLFFGSTSDFQSLMGQIPKTASTVVIRLNLMQYIDQSGLYALEDALVDLRKDNINVLLVDLLNQPRYMMERFGMIPDLIPEKHLFKNFDTCMRWIKDNVKDKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIK9</accession>
    <name>A0A5C6ZIK9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">T9SS type B sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10315</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026341">
        <property type="entry name" value="Bac_Flav_CTERM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022409">
        <property type="entry name" value="PKD/Chitinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000601">
        <property type="entry name" value="PKD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035986">
        <property type="entry name" value="PKD_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00089">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49299">
        <property type="entry name" value="SSF49299"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04131">
        <property type="entry name" value="Bac_Flav_CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50093">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKD" evidence="1">
        <location>
            <begin position="363"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1249" mass="137525" checksum="C450A5CABCC926FF" modified="2019-11-13" version="1">MYRSLYILIIVSLFHFSVKAQGETNIWYFGYNAGLDFGSGTPELLLDGALHTDEGCATISDPDGNLLFYTDGVTVYNRIHEVMPNGNDLHGSFSSTHSAIAVPKPNDFGKYYLFTVDVVGSDGVTTKGLKYSIVDMALNSGFGDVTSAKNIPMEPMVKEKVIAVLNANETGYWVVSHRHNSDEFIAFEITAGGVSTSPTVSAAGFNMGYFGNSGQIKISPDGSRLAVAGGGEVQIFDFDNETGLINNQMTLDNSVNSYGVEFSPNGNLLYIGFYGGVYQFDLQSNNESDIIASKITLSNISNIGYASLQLGPDGKIYVAKTLQYHLDIIHNPNTQGVGCDYEEEGIFLQDRKCMLGLPTFIQSFFNVSFQANNSCVDEQIQFSMNNSQTFDSLIWDFGDGTTSTEENPTHTYETAGDYDVSLSVTSGADNSVDTKTISVYEIPAVAPIVELRQCDDDLDGFSSFNLEEANAEISVNHLNEIITYYESALDAVNASDPIQNSSVYPNDIVSADTIWARVENTNGCYAISQIDLMVSTTQIPNTFTMDFYQCDDGADVTDGIATFDFSSVNTEIQALFPTGQQLTINYHRNQEDALAEMNPIDDISNYQNIGYPSLQDIFVRVENADNNDCLGLGHHITLHVESIPIANTVEALKLCDDDGNGTQAFDTSNIEATLLSGQTDVIISYTDETGNALTSPLPNPFVTHSQIITAKVTNTTSKDPDGACFDETQISFILDAAAMANPVSNFTACDTDNDGQFAFDTSGIEISVLNGQTGMLVSYSDENGNTLPSPLQNPFLTTSQTITVRIQNALSTFCYDETSINFRVSEQPEAGIIMDDLVCDDASNDGVHTFTLSNYDAQILNGQDPDVFSILYFDDSSNANANINALPDNYVVDTTSKTIYARIQNNSNTDCFDITSFELGVHYLPLANAPEPVQVCDDQSNDGMETINLNEQNTAILNSQSTSDNVISYHLSLNDAEANANALNTDFMNTENPQTIYARLENALFPDCFTTSSFQIEVMEQPVLLMDDQWPICEGSTVELVADAGYDEYLWSTGETTPSITVDTEGTYDLTVTNVYRDLRCETSKTLTVVKSNIATITEVETSDWSQDNNAVIIFVDGNGDYEFSLNGFDYQDSNAFNNLDIDDYTVYVRDKNGCGIVSEEIYLLYYPKFFTPNNDGYHDFWQLINSEKEPQNRTFIYDRYGKLIKQLRPDGLGWDGTFNGRPLPNSDYWFTLERENGKSYSGHFSLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIX3</accession>
    <name>A0A5C6ZIX3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Class I SAM-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_11590</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="203" mass="22540" checksum="3EC53FA0685F56A8" modified="2019-11-13" version="1">MKSKQKDYFAEKAEGYDGDKSRTQNVDNIAETILKELSFSKEMHIMDFGSGTGLLLSQIAPYVGEITAVDISASMIGVLQSKMDTIDCKLQIVQMDLTKETLDKKFDAIMSSMTIHHIAHVQALFNTFHALLNDDGTIAIADLDTEDGSFHSEDTGVFHNGFDRNEFLSIAKHAGFRDLKIQTASVMKKETGHFPVFLLTGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ25</accession>
    <name>A0A5C6ZJ25_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TolC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="394" mass="45590" checksum="77B52724D858FEE7" modified="2019-11-13" version="1">MNKYIVFAICGCLFFINGFSQTTNIEELLNEIEQNNIELKGYQSFIESQQLENKSTNNLPDPQLSGFYLPFGDNATGDYTEYQISQSFEFPTVYAARGQWNASKSQQLESGYEKRRQDVLLNAKELLIKLVFLQKQKAIETERRTQSKQVFDQIQELFNKEQVGILDLNKAKIAWIQEQFIVQQIQSDLQIQMSKLKTLNGGKPLASLSALIVLPAEIGTIENLWQEKLTKEPLLQELKANETASFQKVKLEKNKVLPNMALGYNYQGVSGNNYSGFYGGISIPLWSSKNKVKAAEANYEYQQSNTEVITTSLYTQFQETYNQYLLMLEKFNEYQTTMGNLNSEQLLFKAYQLGEYSFMDYYVELQFYRNASDKMLQMEMELQLLQTQLLKHQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJB2</accession>
    <name>A0A5C6ZJB2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF3575 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036709">
        <property type="entry name" value="Autotransporte_beta_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021958">
        <property type="entry name" value="DUF3575"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12099">
        <property type="entry name" value="DUF3575"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103515">
        <property type="entry name" value="SSF103515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023127651" evidence="1">
        <location>
            <begin position="19"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="192" mass="21947" checksum="7181321B3299C60C" modified="2019-11-13" version="1">MKNLCLTLLLCASMVSFSQETDTELIKKSEISTNLLDLVIAGSLNVNYERLFEKNQSLFVGVTFFDTFGYYDAGYLEKTTAVSLKAAYLIYFSKEKQHAGFFFYPQVRLRTGEVTVDDYGYFDYNTDSFNEQDYTYDVSGVSAGFGLGHKWMFNNKFTLTLNGEIARNLGNVNDEYIDNLEARFGVILGYRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJF3</accession>
    <name>A0A5C6ZJF3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Ribonuclease E/G</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_08665</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019307">
        <property type="entry name" value="RNA-bd_AU-1/RNase_E/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004659">
        <property type="entry name" value="RNase_E/G"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30001">
        <property type="entry name" value="PTHR30001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10150">
        <property type="entry name" value="RNase_E_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00757">
        <property type="entry name" value="RNaseEG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD89444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="514" mass="58938" checksum="79BC7014944ED115" modified="2019-11-13" version="1">MEKELIIRSSSDIVDFALLKDGRLVELHKEEEDNNFQVGDVFIAKVRKAVPGLNAAFVNVGYEKDAFLHYHDLGPKLPSLLKFVKRVSTGRHTDFLLKNFQFEKDIDKNGSIANAIKSNQSLLVQIVKEPISTKGPRISSELSIAGRYIVLVPFSDRISISQKIESKDEKERLKRLVKSITPKGFGVIIRTVAEGKKVAEIDKDLQNLLERWTAMCKKLNKAHHPSKVLSEMNKASSILRDIFDDSFSSITIDDETLYGQIKDYVHEIAPNKESIVKLYKNGVPLYEKFGIERQIKTSFGRTVSMAKGAYLVIEHTEAMHVIDVNSGNRSNKEKNQEDTALEVNMISATEIARQLRLRDMGGIIVVDFIDMNKAENRKKLYHHLRDEMNDDKAKHKILPPSKFGLIQITRQRVRPERNIKTKEEDPNGVAGSEIEAPIKVIQRITQDLERLLKKDFKKITLNTHPFIAAFITRGFPSVRSKWFLEHKKWVKVLPRDAYTYLEYHFFDKDGKEIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJF4</accession>
    <name>A0A5C6ZJF4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HU family DNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial histone-like protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000119">
        <property type="entry name" value="Hist_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010992">
        <property type="entry name" value="IHF-like_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33175">
        <property type="entry name" value="PTHR33175"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00216">
        <property type="entry name" value="Bac_DNA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01727">
        <property type="entry name" value="DNABINDINGHU"/>
    </dbReference>
    <dbReference type="SMART" id="SM00411">
        <property type="entry name" value="BHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47729">
        <property type="entry name" value="SSF47729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="90" mass="9460" checksum="C4D1F1E9DEF43FBA" modified="2019-11-13" version="1">MNKTDLINGMAENAGITKAAAKKALDSLLSDVEGALKKGNRVSLVGFGSWSVSKRSAREGRNPQTGKTIQIKAKNVVKFKAGSDLSNAVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJJ8</accession>
    <name>A0A5C6ZJJ8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Peptide MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ESY86_09295</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Membrane</location>
            <topology evidence="1 7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904680">
        <property type="term" value="F:peptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006857">
        <property type="term" value="P:oligopeptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17346">
        <property type="entry name" value="MFS_DtpA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005279">
        <property type="entry name" value="Dipep/tripep_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000109">
        <property type="entry name" value="POT_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018456">
        <property type="entry name" value="PTR2_symporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11654">
        <property type="entry name" value="PTHR11654"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00854">
        <property type="entry name" value="PTR2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00924">
        <property type="entry name" value="yjdL_sub1_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01023">
        <property type="entry name" value="PTR2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="117"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="156"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="182"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="248"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="286"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="318"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="361"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="398"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="428"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="462"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="492"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="523"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="562"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="9">
        <location>
            <begin position="22"/>
            <end position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD89232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="595" mass="66147" checksum="856C0F846EC79DAD" modified="2019-11-13" version="1">MKTDIENLFKDTVLGHPVGLFILFFTEMWERFSFYGMRILLILFLTAPLLSDNPGWDWPREHALSLIGTYASLLYLTPIVGGWIADKITGYRIAVIIGCLIMTLGHAAMAFDTTLTFYIGLALLVIGTGFFKPNITSIISEMYKTRESKKDGAYTIFYMGVNAGAFFGMMLCGYLAENYGWHWGFGLAGIFMLLGMLQFMLAHKIFGKIGDKPARKKDVVIAVNTSDADSENVEEELETEIKLNPFTLFDYVLIILSSVGGLLYLFNDPLETIYAKSLMPFELWGMSGTNIVVLAALALFLVLLITRIARYLPIVRDRLIAVTIFALFTVFFFAFFEQSLGSMTLFANDYTDRSLEGNSAIIFKIIDALLTTIPLIIITYVITLIFKKTFTKIGASNIVLAIAFLGVWGLVIFRLYDKFSQTEMIVDATWFGILNSFFIITLAPIFSRWWESKYNPSAAMKYGIGLVLLGLGFGILSFGAADIPPGAKTASVSMIFLILAYLLHTMGELCLSPLGLSYLSKLVPARMIGFMFGVWYLAIAVGQKAANTMGGMIDKISAEYSLGIFFLIFTLIPIGVGIISMLLNPLLKKLMHGVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJY3</accession>
    <name>A0A5C6ZJY3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Fumarate reductase/succinate dehydrogenase flavoprotein subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_08235</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-binding_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037099">
        <property type="entry name" value="Fum_R/Succ_DH_flav-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015939">
        <property type="entry name" value="Fum_Rdtase/Succ_DH_flav-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030664">
        <property type="entry name" value="SdhA/FrdA/AprA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011280">
        <property type="entry name" value="Succ_DH/Fum_Rdt_flav_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11632">
        <property type="entry name" value="PTHR11632"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11632:SF53">
        <property type="entry name" value="PTHR11632:SF53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02910">
        <property type="entry name" value="Succ_DH_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46977">
        <property type="entry name" value="SSF46977"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="SSF56425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01811">
        <property type="entry name" value="sdhA_Bsu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_2" evidence="4">
        <location>
            <begin position="35"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="Succ_DH_flav_C" evidence="5">
        <location>
            <begin position="531"/>
            <end position="664"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD89370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="665" mass="74458" checksum="659111481F93103D" modified="2019-11-13" version="1">MALDSKIPKGPLKDKWTKHKNDINLVNPANKRNIDVIVVGTGLAGGSAAATLAELGYNVKAFCFQDSPRRAHSIAAQGGINAAKNYQGDGDSVYRLFYDTVKGGDYRSREANVYRLAEVSANIIDQCVAQGVPFAREYGGLLDNRSFGGVLVSRTFYAAGQTGQQLLLGAYSAMNRQIGRGKITMYNRHEMLDVVVVDGKARGIIARDLVSGEIERHSAHAVVLGSGGYGNVFFLSTNAMGSNVTAAWKAYKRGAYFANPCYTQIHPTCIPVSGDHQSKLTLMSESLRNDGRIWVPERKEDVEAIRSRKMKPTEIPEEHRDYYLERRYPAFGNLVPRDVASRAAKERCDAGYGVNKTGEAVYLDFASSFMRYGKEQAHVKGLDENDEQLVKKLGQEIIKEKYGNLFQMYEKIVDENPYETPMMIYPAVHYTMGGLWVDYNLQTTVKGLYSIGEANFSDHGANRLGASALMQGLADGYFVLPYTIGDYLAHDIRTGEIPTNTKEFDEAEKVVKDNIEHLINNKGTHPVDYFHKRLGKIMWNKCGMARNAEDLKSAIKEISDLRAEFWKDVRVPGTANEFNEELAKAGRVADFLELGELFAKDALEREESAGGHFREEYQTAEGEATRREEFQFVSAWEYNGEPKDSILHKENLEYEDIEVKTRSYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK07</accession>
    <name>A0A5C6ZK07_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023103119" evidence="1">
        <location>
            <begin position="19"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="134" mass="15204" checksum="D2CBE33CDA78DAD6" modified="2019-11-13" version="1">MKRLATLILFFTISTGFAQGYPQIEGASSSITETADSITDAYDQKLSMTSQQKAIFKIRVEDFLKIRQNIMATKTGKDQLNALVNLQAEETLAMNDVLTRLQMRVYKKVKREIQPLKVVDMPNDASKSKKKKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK16</accession>
    <name>A0A5C6ZK16_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PorT family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025665">
        <property type="entry name" value="OMP_b-brl_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13568">
        <property type="entry name" value="OMP_b-brl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OMP_b-brl_2" evidence="1">
        <location>
            <begin position="49"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="219" mass="25281" checksum="E7547D9B3025C57B" modified="2019-11-13" version="1">MIFRLNGYIWWHMIAHKCFKPNSLYAMKKNLFIGLVILISFNMYSQGKIGVFAGINASSLSDGFLKSSYIGSNSFSFHIGGLYEFPLTEKIAFRPKLLFSQQGNREDFDNNIKYETSYINIPLDFKFFKKPYILFGPQVGFLIDTKKKEIDFGDLESLDYGLNLGIGIDIKDFFIEFNIYQGLNKLIEVEYKQTNPFRDIDIEATNTVLQLTLGYNLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKB3</accession>
    <name>A0A5C6ZKB3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">M1 family metallopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_05965</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023063231" evidence="1">
        <location>
            <begin position="21"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M1" evidence="2">
        <location>
            <begin position="420"/>
            <end position="584"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="768" mass="88905" checksum="A4C9D8A103AF3D45" modified="2019-11-13" version="1">MKFFKYLSFCLAFLSLNAMAQDQDADTEARKPGHTNQNKFKQLYDEFATPNMFRTGSGAPGPGYYQQQADYKMDVEINDETAVLTGEETITYTNNSPDELSYLWVQLDQNVRQKDSPSKDIQSSRITPAMTPSTYASSYLEKGFEGGFNIEKVTTTDGKALAHMINQTMMRVELPKPMKTGDQFSFDIKWWYQINDHVKDGGRSGFELFPDGNRNYVIAQFYPRMAVYNDVEGWQNSQFWGRDEFALPFGNFEVNITVPADHLLDATGVLTNRSEVFSKDMMKRYEKAQKSFDNPVVISTQAEAEVREKGRSTKKQTWKLKAENVRDFGFATSRKYIWDMMAVKIGDRDIMAVSLYSKEGNPLWEEWSTRAVASTLKSYSRMTFEYPYHKAISVHAKRQGMEYPMICWNYGRPDEDGKYDDRTKYGMISVIVHEVGHNFFPMIVNSDERQWTWMDEGLNTFLQYVAEQDFGESHPTALSPGDVTYPSRRGPAKNITYYMGGNQDYIAPIMTKGLNTYQFGNNAYGKPATALNILRETVMGRELFDYAFKEYAQRWMFKHPTPEDFFRTMEDASAFDLDWYWRGWFYTTDWVDIGIKDVKKYYVSSEPNQYARNYAASRNIDLSDMDLVYMAEEGDDEYDAKLKEGSAEENSSTLKEYMMDNFTPEERKNIEQPKYFYTVTFEKPGGLVMPIIVEYTYADGSAKTETYPAQIWRLNDKEVSKEIASQKEIISIKIDPKLETADIDTANNSWPKEVEESDFDKFKDKVKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKD8</accession>
    <name>A0A5C6ZKD8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Sigma-70 family RNA polymerase sigma factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_09945</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009042">
        <property type="entry name" value="RNA_pol_sigma70_r1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007624">
        <property type="entry name" value="RNA_pol_sigma70_r3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00140">
        <property type="entry name" value="Sigma70_r1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04539">
        <property type="entry name" value="Sigma70_r3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000770">
        <property type="entry name" value="RNA_pol_sigma-SigE/K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r1_2" evidence="5">
        <location>
            <begin position="17"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r2" evidence="7">
        <location>
            <begin position="56"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r3" evidence="6">
        <location>
            <begin position="135"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4" evidence="8">
        <location>
            <begin position="222"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD89084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="287" mass="32831" checksum="C120419F6EAE73ED" modified="2019-11-13" version="1">MRQLKITKQVTNRETASLDKYLQEIGKVDLITADEEVELAQRIKAGDQSALEKLTKANLRFVVSVAKQYQNQGLTLPDLINEGNLGLIKAAQRFDETRGFKFISYAVWWIRQSILQALAEQSRIVRLPLNKIGSINKINKTFAFLEQSHERPPSAEEIAKELDMTINDVKESMKNSGRHVSMDAPLVEGEDSNLYDVLRSGESPNPDKDLMHESLRTEIERALETLTPREADVIRLYFGLGNQHPMTLEEIGETFDLTRERVRQIKEKAIRRLKHTSRSKILKTYLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKF9</accession>
    <name>A0A5C6ZKF9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="208" mass="24257" checksum="B90DA51DDA11E9DC" modified="2019-11-13" version="1">MKNLQSFLLLIIIQSFLVFFSKELLETNQVFVSSLSEKISYDQINEILAFKEKWGWIVYIFIPILLFIKIVIITTVINIGCFLFGKNISYSQIFNITIKSEFIFLLVIVFKTAWFYFFEQDYNLNDLQFFYPLSALNIVGYEGIDPWWIYPLQVFNLFELAYWFILAYLIGKAINSDTDKGINIVASSNGVALLIWVVGVMFFTLNVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKH2</accession>
    <name>A0A5C6ZKH2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_02350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022995075" evidence="1">
        <location>
            <begin position="21"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="119" mass="13239" checksum="37D2182100C0B43C" modified="2019-11-13" version="1">MKNALTILALFAMALSFSQAKNLNGTISERNIIVSNMAVSITVDSAEELEKTFKISDIEDFMQSLSENESISIEIVCNTKQDNANMNKSVTYKVNANNRGDFLKYATKIRNAALAFYNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKR7</accession>
    <name>A0A5C6ZKR7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional repressor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_03440</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Fur family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07153">
        <property type="entry name" value="Fur_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002481">
        <property type="entry name" value="FUR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043135">
        <property type="entry name" value="Fur_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33202">
        <property type="entry name" value="PTHR33202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01475">
        <property type="entry name" value="FUR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="151" mass="18004" checksum="3B5835FB6F53B3CE" modified="2019-11-13" version="1">MSKKTEQTNQEIVKNVFTKFLEDKGHRKTPERYAILQEIYDSEEHFDIESLYIKMKNKNYRVSRATLYNTIEILMECALVRKHQFGQNQAHYEKSYFDKQHDHVILTDTGEVIEFCDPRIQSIKKTIEEVFDISISNHSLYFYGTKNKPTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKS3</accession>
    <name>A0A5C6ZKS3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">PAS domain S-box protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_02955</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000156">
        <property type="term" value="F:phosphorelay response regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008984">
        <property type="term" value="F:protein-glutamate methylesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035909">
        <property type="entry name" value="CheB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022642">
        <property type="entry name" value="CheR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000780">
        <property type="entry name" value="CheR_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022641">
        <property type="entry name" value="CheR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000673">
        <property type="entry name" value="Sig_transdc_resp-reg_Me-estase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01339">
        <property type="entry name" value="CheB_methylest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01739">
        <property type="entry name" value="CheR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03705">
        <property type="entry name" value="CheR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00996">
        <property type="entry name" value="CHERMTFRASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00138">
        <property type="entry name" value="MeTrc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52738">
        <property type="entry name" value="SSF52738"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50122">
        <property type="entry name" value="CHEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50123">
        <property type="entry name" value="CHER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CheB-type methylesterase" evidence="6">
        <location>
            <begin position="21"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="CheR-type methyltransferase" evidence="7">
        <location>
            <begin position="221"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="4">
        <location>
            <begin position="1129"/>
            <end position="1199"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="5">
        <location>
            <begin position="1202"/>
            <end position="1254"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="1258"/>
            <end position="1480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="681"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="684"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="27"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD90931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1487" mass="168938" checksum="7AB5E14C5BAB6DCF" modified="2019-11-13" version="1">MSQKENKQEESLEKSKNKFPVVGVGASAGGLAAFKKLLSAIPEDSGMAYVLVQHLDPNHDSLLPELLQKATKIPVLEITDDIKVAPNNIYIIPSNKMLLATEGVLKLNPRPAPKSNNINLPINLFFNSLALVHQSHSLGVVLTGTGSDGTAGLEAIKEQGGMTFAQDEASAEWKDMPRNAIDAGVVDFILPPENIPKKIIAMLAKLDKDGQEKDPVSEPDEQAFRQILSLLRTRKGTDFTYYKQTTIHRRILRRMGINKNKKPSNYLDYLRDNTEEQDLLYQDLLIPVTSFFRDSDIFEKLCESILPKIAQNNKDNSTIRLWVAGCSTGQEAYSLAMCIKEYLNAHPELYKTSGASSKEKIQIFASDISEPAVAIARKGVYTKDEVDGVSSERLKKFFSKYNGGYQINKELRELCVFAVHNFLKDPPFGSMDLISCRNVLIYFQPYLQKRALTTFHYALKAKSYLLLGKSETTGSTSDHFTAVSKSDKLFLRNDVHGKLMFPYSQQHDQTLHKGKNRTTAIENRRTDFQKTADELLLSNYTPASVVVDESMDIVLFRGNTGDYLGQKGGAPSHNLMKMAKGGLAFELRNILHKVKKSNASEKKEEIPFHINDNRQLIAIEAVPLPNMEESHYLILFYPPLAPASSTSGGKRDKKDEKDLRIEQLENELVQSREDMRAISEDQEAANEELQSANEELLSSGEELQSLNEELETSKEELQSTNEEITAVNQELIGLNEQVTDERNFAEGIIMTVREPLVVLDKNLKVITANESFYKTFKVNETDTEGSLIYELGNKQWNIPALRNLLESILPEAESFFDFEMIHTFESIGERTMLLNARKIKGERESRKMILLAIEDITEKKRLLQREQELLEKFKNLVMQAPVAIMLLSGEDYQVELANDSYLSLVEKDKHLIGKSIFESLPELKTQGIKALFDEVVKSGEPYFGKEVEVKINRNTKSKRGFYNFVYQPMNDGDPAATGIMVIAMEVTEQVLARKKISETVHKYNEMIYSSPSLMAILEGEDLTLTVANDAFLDQLGKGRGVIGKRFLDSAPELEEQGLGDLLREVYKTGKPYHAHERRVILVRDGKRKLSYYNFVFQPQRDIQGNVVGVAIIASEFTAQAEFNKEIRESEARYHQMTELVPDMISNATAAGEVFYYNKAWTDFTGWDMKKLIEQGWEKLIHPEELPTVEQNWNSALKAENAFEMEFRILDRNGDYKWHITRSIPVKDENGNILTWLAANTEIHKLKEEEKRKEGFLKMVSHELKTPITSIKGYTQLLLSFLEDDTDIQWESLPIKPSLQRIDSQITRLTRLISEMLDLDRLEDNQLLLQNEVFNLNELVEATIKDIEYAHKQTNIRLKIESACQVHADRDRIGQVLINFITNAIKYSPNDQNVEIKVFQTNDKTVSVSVKDHGIGIEKKDQQNIFKRFYRVSGKNEETFAGFGIGLYLAKEMIERHKGRVKVKSKKGEGSEFIFTLPVHTKTNEKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKT5</accession>
    <name>A0A5C6ZKT5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">23S rRNA (Adenine(1618)-N(6))-methyltransferase RlmF</fullName>
            <ecNumber evidence="2">2.1.1.181</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rlmF</name>
        <name evidence="2" type="ORF">ESY86_03545</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.181" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052907">
        <property type="term" value="F:23S rRNA (adenine(1618)-N(6))-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010286">
        <property type="entry name" value="METTL16/RlmF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016909">
        <property type="entry name" value="rRNA_lsu_MeTfrase_F"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13393">
        <property type="entry name" value="PTHR13393"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05971">
        <property type="entry name" value="Methyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029038">
        <property type="entry name" value="Mtase_YbiN_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="298" mass="33646" checksum="8D7B9C9E6969EDA8" modified="2019-11-13" version="1">MNKNNAHKKPYDFKLLTEQMPNLAEFVFTNQYGTETIDFANPKAVKALNTALLKAHYKIEYWSFPDDNLCPPIPGRVEYIHLLNDLLKTSGINENITILDLGTGATCIYPLLGNAEYGWKFIASETDKPAFKTAEKIVKKNSLENAITLRFQDNHQHILTGILKPSEQISASMCNPPFFKDEAEAEEKNLQKLKGLGSNANTTLRNFSGTAKELCYPGGEKAYLHNYLYQSSLLKTNCFWYTSLVSKHALVKSMQASLKKLGATQIKVLEMKLGNKVSRVVAWTFLSEEAQKKWNPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKV2</accession>
    <name>A0A5C6ZKV2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Collagen-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_06220</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0176">Collagen</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="176" mass="19443" checksum="DB63A0BAD9FA0D1E" modified="2019-11-13" version="1">MKKILSLVAITALLFTACEGDQGPPGPPGFNGINADEYAALSFETPPINFQYFNDSGLQEVEVSLPYDILDSDVVLVYRLDEVVTIDGQATDAWSPLPQNFFLNDNDVIQYVFNHTFADVKLLIDGNFDLSTLDADFTQNQIFRIVILPADAINGLDTSNIDNVMEAVNITEFKTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKY4</accession>
    <name>A0A5C6ZKY4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DNA gyrase subunit B</fullName>
            <ecNumber evidence="10">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10 12" type="primary">gyrB</name>
        <name evidence="12" type="ORF">ESY86_04640</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="10">Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="10">Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the type II topoisomerase GyrB family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the type II topoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="10"/>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03366">
        <property type="entry name" value="TOPRIM_TopoIIA_GyrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.670">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01898">
        <property type="entry name" value="GyrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002288">
        <property type="entry name" value="DNA_gyrase_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011557">
        <property type="entry name" value="GyrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001241">
        <property type="entry name" value="Topo_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013759">
        <property type="entry name" value="Topo_IIA_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013506">
        <property type="entry name" value="Topo_IIA_bsu_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018522">
        <property type="entry name" value="TopoIIA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034160">
        <property type="entry name" value="TOPRIM_GyrB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00204">
        <property type="entry name" value="DNA_gyraseB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00986">
        <property type="entry name" value="DNA_gyraseB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00433">
        <property type="entry name" value="TOP2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56719">
        <property type="entry name" value="SSF56719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01059">
        <property type="entry name" value="gyrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00177">
        <property type="entry name" value="TOPOISOMERASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 10 12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="Toprim" evidence="11">
        <location>
            <begin position="427"/>
            <end position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TXD90047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="645" mass="72122" checksum="7DE9783667AE3064" modified="2019-11-13" version="1">MSEENKKQYSADSIQALEGMEHVRMRPSMYIGDVGTRGLHHLVYEVVDNSIDEAMGGYCDNITVTINEDNSVTTEDDGRGIPVDLHKKEGVSALQVVMTKIGAGGKFDKDSYKVSGGLHGVGVSCVNALSAHLTATVHKDGTIWQQEYEKGKAMYPVKAVGTTDKRGTVVTFRPDPSIFTQTLEFNYDTLASRMRELSYLNKGITIHLIDKRFKKDNGEFEGETFHSKEGLKEFIKFLDGSREPIIKEIISFEGEKNDVPVEVAMVYNTSYAENLHSYVNNINTHEGGTHLSGFRRGLTHTLKKYAESTGMLDKLKFDIAGDDFREGLTAIISVKVQEPQFEGQTKTKLGNREVSASVSQAVSEMLTNYLEEHPDDAKIIVQKVILAAQARHAAQKARDMVQRKTVMSLGGLPGKLSDCSEQDPSLCEVFLVEGDSAGGTAKQGRDRKFQAILPLRGKILNVEKAMTHKVFENEEIKNIYTALGVTIGTEEDSKALNLSKLRYHKVVIMCDADIDGSHIATLILTFFFRYMKELIEGGHIYIATPPLYLIKKGAKKQYAWSDKERDGIMKEFGENSKIQRYKGLGEMNAEQLWDTTMNPEFRTMRLVQIDNGTEADRIFSMLMGDEVPPRREFIEKNAIYANIDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL25</accession>
    <name>A0A5C6ZL25_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Lacal_2735 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_06660</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="56" mass="6621" checksum="AE896CFFEC1ADB96" modified="2019-11-13" version="1">MFNLFKKTSEADKLQKKYEKLMKEWHALSTTNRGESDKKYAEAQEVQDQIVALQDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL85</accession>
    <name>A0A5C6ZL85_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_00495</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1003" mass="115382" checksum="CB43B6F194D07534" modified="2019-11-13" version="1">MSDLNYIETARKLSNAENYTFLRSEGQKHIEILGNELWTDFNAHDPGITILEVLCYVITELGYRANFSIEDLLTGKDHKISNATFFPCSEIMTNAPLTELDYRKLIIDVEGVNNAWFVFHSVDNNGEPTALKNEVRIYVNFKEDKLSLSSVNKFGETLLPLRLEGLARPIVELSDDRELGQLNEVAVQYSWTDGDRFIQVDIKSEIESWGDEKVTWLEHFSNPANIAITDIGQEAAYVRITTVNNADPVQSIQFNVFPYDISEVSNTETHFSDIENLVHIVSKFNEKRKKVNAIYSEVKAKLNKNRNLTEDWLCLETITNLDIGICMDVQLSSGTDAEEALANIYQTVDGLLDPPIRFYTLRQMLDLDYKPRDIFKGPSLDHGFLIDSEVDAAQLPDCIHASDIIAAIMGVEGVELVRNLLMTAYDINGKPIEGKANQNWCIHLSGAVRPVFQPRWSKILLFRDSIPFVISQAGENELDRGIFYLKVENNNYKLKNPKKDFEFPAGKHYQLNDYYSIQHDFPSTYGIGEGELPLASTNLRKAQAKQLKAYLLHFDQLLADFFKQLYMAKEYLNTTTLTSTYATNLIKDIPGIADEFFYSEAYDTSFETGIINGGNERSHYETNEDFYDRRNRFLDHLLARFGESFGDYVFMMYRMQENAKGISELKLPLQDLVEDKQRFLNKVADVSYSRGLGVDYDQEPDASSSFWMLPNRSGFANRISALLGINQIPFQDIVDTTAKDHWIIKTETKNLPIKLMNPPGFTQDEKWNLVFGLFNDIRNYQTVKFTNTYIYFVDFAGVRIARFDETFDSVLEAEEFIPSLFQFITGYLENFYCVEHVLLRPFFTDGLTDIDLFPVCLNDECVQSDLDLFYANQDPFSFKATLIFPGWLPRFGNRYFRKYAENLIRKEAPAHTQIKICWVGKDDMIAFQQVYQPWLHAFREMRRKYCNSSLSNEEKTRYNSQLSNMMKAMKALNTIFEKGTLHDCLESELDNPIILNNSTLGTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLI9</accession>
    <name>A0A5C6ZLI9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Signal recognition particle receptor FtsY</fullName>
            <shortName evidence="5">SRP receptor</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">ftsY</name>
        <name evidence="7" type="ORF">ESY86_03935</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
            <orientation evidence="5">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the GTP-binding SRP family. FtsY subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031226">
        <property type="term" value="C:intrinsic component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00920">
        <property type="entry name" value="FtsY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013822">
        <property type="entry name" value="Signal_recog_particl_SRP54_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004390">
        <property type="entry name" value="SR_rcpt_FtsY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036225">
        <property type="entry name" value="SRP/SRP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042101">
        <property type="entry name" value="SRP54_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43134:SF7">
        <property type="entry name" value="PTHR43134:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02881">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00963">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47364">
        <property type="entry name" value="SSF47364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00064">
        <property type="entry name" value="ftsY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00300">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 5" id="KW-0675">Receptor</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SRP54" evidence="6">
        <location>
            <begin position="290"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="123"/>
            <end position="130"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="205"/>
            <end position="209"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="269"/>
            <end position="272"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD90525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="317" mass="34581" checksum="BA94AC2B480F8557" modified="2019-11-13" version="1">MSFFKKIFSSEKKETLDKGLEKSKTSFFGKLNKAVAGKSKVDEDVLDNLEEILVSSDVGVNTTLKIIDRIEARVAQDKYLGTSELNQILREEIAGLLSETNSGEDTEFVIPKDKKPYVLMVVGVNGVGKTTTIGKLAYQFKKQGLKVVLGAADTFRAAAIEQLQVWADRVDVPMIRQNMGSDPASVAFDSVKAGVDQDADVIIIDTAGRLHNKINLMNELSKVKRVMQKVIDDAPHDVLLVLDGSTGQNAFEQAKQFTAATEVTSLAVTKLDGTAKGGVVIGISDQFKIPVKYIGVGEGLEDLQVFNKIEFVDSFFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLJ0</accession>
    <name>A0A5C6ZLJ0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Helix-turn-helix transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_02780</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="SSF55008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMA" evidence="2">
        <location>
            <begin position="2"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="97"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="188" mass="21851" checksum="F95D771F5BC6382C" modified="2019-11-13" version="1">MKQNFYIKNMVCDRCIKVLKNEIEAQDIALEEIELGRVQLDIQDDSELEKLKNIIESNGFELIDAAEDKLTEQVKIQLIKIVDDLPLELHEKLSTHLAKTMHQDYSKVSKVFSSTEGITIEKYFIKLKIEKVKELIQAQEKNFTEISQLLDYSHLNHLSRQFKAETGLSLSEYKAEQKNTRNPLDQIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLP2</accession>
    <name>A0A5C6ZLP2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4835 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_01040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032274">
        <property type="entry name" value="DUF4835"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16119">
        <property type="entry name" value="DUF4835"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023087545" evidence="1">
        <location>
            <begin position="19"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="295" mass="34117" checksum="7B8D891B9F6A236B" modified="2019-11-13" version="1">MRKLILFLAVVTSFSAWAQELRCEVVVNAQQTGNENVQVFKTLERQLTEFVNNTEWTKNSYKVQERINCSMIITINDYNSDAFQGTIQVQASRPVFDSSYSTPTYNFNDRDFNFQYLEFQNLVFNPNQFESNLVSVIAFHVYMILGIDAETFEVNGGDEYLKQAQTIVNYTQQLNTKGWKLEDGQQSRFVLIDNILSPTFKEFRTAMYNYHRNGLDVMSTDAKTGKNAIADSVLELQVMNRRRPNSFLLRVFFDAKADEIEQIFSDGPTVNVAELIEILTKISPTRSSQWRNINF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLZ3</accession>
    <name>A0A5C6ZLZ3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DUF4968 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_02875</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032513">
        <property type="entry name" value="AGL_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025887">
        <property type="entry name" value="Glyco_hydro_31_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16338">
        <property type="entry name" value="DUF4968"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13802">
        <property type="entry name" value="Gal_mutarotas_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023107930" evidence="3">
        <location>
            <begin position="20"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4968" evidence="5">
        <location>
            <begin position="31"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="Gal_mutarotas_2" evidence="4">
        <location>
            <begin position="142"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD90915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="797" mass="91126" checksum="538BE9004C3D7B76" modified="2019-11-13" version="1">MKKRILLILFFASISFGFAQNPNRTFLSMSQTQNGAELKVSDGLYKINFYTSEIVETSFIPKGENANPESHAVVAKPNAVAVQFKESNGNIQLKTEGLEVVIQKRPFQISYHYKEQPLISEKFGYIKNDSLETIQFNLNKEEVLYGGGARALGMNRRGNRLQLYNRAHYGYETRSELMNFTLPIVMSSEKYMVHFDNAPIGFLDLDSKKDNTLTYETISGRKTYQVIAGDSWYDIVDSYTHLTGKQPMLPRWALGNFSSRFGYHSQNEVLETIAKFREEEIPVDAIILDLYWFGKDLKGTMGNLEFDRDSFPNPKQMIADLKKENVETILITEPFVLTTSKRWDEAVTKNILAKDSLGKPFTYDFYFGNTGLIDIYSKAGNQWFKEIYKDLSKMGVNGFWGDLGEPEVHPSDLIHATGTADEVHNIYGHDWAKLVYEASLEANPNKRPFILMRAGYSGSQRYGLVPWSGDVSRSWGGLQSQPEIALQMGMQGLAYMHSDLGGFAGANLDDELYARWLQYGVFQPIFRPHAQEDVASEPVFRSEKAKALAKQAIELRYQFLAYNYNLMYENHQTGAPLMRPLFFEEPDNEMLFDYSAAYLWGQDILVAPILKAGVEEQEVYFPKTANWFDFYTDEHFEGGTTQTIQVKENSIPTFVRGGSFMPMAKIVQSTKLHTAGTFELHYYFDASVSNSEREFYNDAGDGIDLIEKGDYELVEYEANYNRNKLKFEFELEAGSHQHLSGKSFELVVHNIQNAPRRIKINHKKIPVNWDAETKTLKIPIIWANTSEDIDLKIKLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM59</accession>
    <name>A0A5C6ZM59_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4199 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03165</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025250">
        <property type="entry name" value="DUF4199"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13858">
        <property type="entry name" value="DUF4199"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="167" mass="18474" checksum="80A644968BD4EB14" modified="2019-11-13" version="1">MKPIAYTYGLYLGLLTVVGLVIQYVASLERNWAVSIISLALTIVIFYYGIKTYKTQNHNFLSIKEAIKVGLAMAVIGGVIAAAYAFVHYLYVQPEFVEGIREKAYQDMTAGTQNMSGEQLDTATTMMNIFTSPFFLATMILISQLFFGLIISLIMGAVMKKEDPSLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM68</accession>
    <name>A0A5C6ZM68_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_04620</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="110" mass="12596" checksum="B4340250A2CC9822" modified="2019-11-13" version="1">MFTDKNSGIIVNQFDPRHQRSVFGTQMTQILQMFADKNTGIHANKFNPRHQRSIFGTQTTQILQMFTAKNSGIRANQFDPRHQRSMIGTQMTQILQMLTAKNSGDPRKSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM75</accession>
    <name>A0A5C6ZM75_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Alpha-acetolactate decarboxylase</fullName>
            <ecNumber evidence="4">4.1.1.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_02740</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2S)-2-acetolactate + H(+) = (R)-acetoin + CO2</text>
            <dbReference type="Rhea" id="RHEA:21580"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15686"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58476"/>
            <dbReference type="EC" id="4.1.1.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Polyol metabolism; (R,R)-butane-2,3-diol biosynthesis; (R,R)-butane-2,3-diol from pyruvate: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the alpha-acetolactate decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.5" evidence="4"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00626">
        <property type="reaction ID" value="UER00678"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047605">
        <property type="term" value="F:acetolactate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045151">
        <property type="term" value="P:acetoin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005128">
        <property type="entry name" value="Acetolactate_a_deCO2ase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03306">
        <property type="entry name" value="AAL_decarboxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0005">Acetoin biosynthesis</keyword>
    <keyword evidence="6" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD90892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="237" mass="26463" checksum="C9264A5C612F6CE9" modified="2019-11-13" version="1">MKHKLLFSVLIGLLFTSCENQETDGTAHYTGALKTLMSGDLRATASLDSLSRMRNSYALGAIENLKGEVQIFNAEPFNSQVVNSQVVIDNSFKAKASLLVWAQVDAWVELSIPSEVKDISQLEQFIMKHAKAQGLDVEKPFPFLLEGKAMSLNWHVIDWIDGDTIHTHEKHKTSGSNGVLKNQKVEVLGFYSEKHKGVFTHHSTLMHMHFKTDNGDLAGHVDDLELAHSMILKLPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM77</accession>
    <name>A0A5C6ZM77_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Hemolysin III family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_03270</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0073 (Hly-III) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019835">
        <property type="term" value="P:cytolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004254">
        <property type="entry name" value="AdipoR/HlyIII-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005744">
        <property type="entry name" value="Hy-lIII"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20855">
        <property type="entry name" value="PTHR20855"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03006">
        <property type="entry name" value="HlyIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01065">
        <property type="entry name" value="hlyIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="40"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="76"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="130"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="186"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD90401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="208" mass="23666" checksum="10C58D7487C82DA0" modified="2019-11-13" version="1">MRIQSDFEEKLNAWSHGIGAVLGIIGLFLLIVFLEKNVPFAMFSVVIYGLSIVVLFLASTFYHAVKGERRKHYFRIVDHISIYLLIAGTYTPVLLIMLPDSLGWTLFFVVWGIAAFGLILKIFFTGRFEIFSTLLYLVMGWLIVFDYPTLAARMTANGLALFFAGGAFYTIGIVFYAVHKIPYNHVIWHLFVLGGAICHFLMIYLYVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM87</accession>
    <name>A0A5C6ZM87_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_00180</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039426">
        <property type="entry name" value="BtuB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30069">
        <property type="entry name" value="PTHR30069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022785630" evidence="5">
        <location>
            <begin position="19"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="7">
        <location>
            <begin position="117"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="6">
        <location>
            <begin position="255"/>
            <end position="797"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD91052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="799" mass="89793" checksum="BCCFF50D2E8BA6E6" modified="2019-11-13" version="1">MKYILVCIALSFVGIGNAQDCAYTFKGQLTDFHDGTPIAGAAIYLKERDSYTTSDIDGKFTLENLCKGPLTLVISHIACDTKTNTYAITGNRTETIYMEHHIEELKEVSVTGRTASKETTTAQETLLKAETIDKYSALNLGDALKEVAGVSSINTGSTIVKPMINGLHSSRLLILNNNVRLQDQEWGIEHAPNVDINSAAQISVIKGSGALAYGGDAIGGVVVINPSRIILIDSLYGKVTTGAQTNGRGYNIATTVNKSFASGWFGSVTGSYKQNGDFEAPDYQLTNTGVKSTNFSLRTGKKTFESGFEAYYSYVDNEIGILRASHIGNIQDLVDAINTQQPLIIRDFSYAINAPKQEVTHQLAKASYYKRFKNFGKLSLQYDYQNNQRYEYDIRVGDDRDKAALDLTLQTHSARADVVVDAKYGLKVNFGILGNYQNNFANPDTGVRRLIPDYDKYDFGSYLTSEYKLNKNWTLDAGLRYDFNRIDAKKFYETSRWEERGYDADFSQFVIDDLGTQLLTNPIFDYHNLSASAGAKYRINEKSYVLGNYSLSNRPPNPSELFSDGLHHSAARIELGDIRLKPETSNRVAGSYHYTDSKFDLNVEAFYNHIDGFMYLQPTGVQQTIRGAFPVWEYQKTTANLYGIDLTAQYAFNEQWRIKDKSAYIKGTDEDNNRDLIDMPAFNTVNELIYSKPDWHNFSASLQSEWVFEQKAFPNNNFEVFIAATNENLLVDISTPPPAYHLLHFYTDLDFKVSKNTNLNLAVSVNNILSTNYRAYLNRLRYFADDLGRNVALQLQLNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMF7</accession>
    <name>A0A5C6ZMF7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">BlaI/MecI/CopY family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BlaI transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005650">
        <property type="entry name" value="BlaI_family"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34134">
        <property type="entry name" value="PTHR34134"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03965">
        <property type="entry name" value="Penicillinase_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019455">
        <property type="entry name" value="CopR_AtkY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="128" mass="15095" checksum="F6A02AD4A6D60262" modified="2019-11-13" version="1">MDIKQLNRTELQIMKYIWQLKSGFMKDIVEQFPEPRPAYTTISTLLKRMCDKEYIGFKRLGRDKEYFPILKKNAYLATQLNGMIDNFFNDSKSQFASFFTKNADLSLQEMEELQALLEQKISSKKSSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMI1</accession>
    <name>A0A5C6ZMI1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_05185</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012318">
        <property type="entry name" value="HTH_CRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13545">
        <property type="entry name" value="HTH_Crp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00419">
        <property type="entry name" value="HTH_CRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51063">
        <property type="entry name" value="HTH_CRP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="3"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="3">
        <location>
            <begin position="159"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="HTH crp-type" evidence="5">
        <location>
            <begin position="275"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD90143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="356" mass="39742" checksum="FE4BF46AEE1F42C9" modified="2019-11-13" version="1">MKKVLIIEDNKDVRENTADILELSNYKVSTAENGKIGLDLAMKLLPDVIVCDIMMPELNGYEVLQTLSKNTKTASIPFIFLTAKTEKTDVRKGMNLGADDYLTKPFSETELLEAIDCRLKKHDFLKMEFSRNIKGVSQFIEEASKFLDLEHLSRDYTAKKYNKKELVFMEGNAANSLYFIECGVVKTFKTTEKGKEFVTGFYGTGHFVGQLSLLSDHGTYMESAAILEEAELYEIPKLDFTTLIHGNKDVANKFVSLVSNNLVAMQEEMMNVAFATVRQRVARALVHLHTNGILSNNEANGISIVREDFAGLIGTATETAIRMLTEFKDEGFISIGAARKIVIEDIEALEAIAVFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZML4</accession>
    <name>A0A5C6ZML4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">GH3 auxin-responsive promoter family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_00270</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004993">
        <property type="entry name" value="GH3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31901">
        <property type="entry name" value="PTHR31901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03321">
        <property type="entry name" value="GH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="507" mass="57572" checksum="FD3DBE791BD21908" modified="2019-11-13" version="1">MAILGNIIKGIITIKDSFSFEINHIEKQQAILKTLLEKAKDTQFGNYYKFGEILAADDIAKAYAERLPYFDYNKLNGEWWHKMHQGETNVTWPGTPTYFALSSGTTGKTSKRIPVTDEMIEAIRQAGIKQIFALNNFDLPSDFFEKEIMALGSSTDLEQRDKHLEGEISGITASNIPFWFKGYYKPGEDIAKIADWDSRVQRIAEGAKNWDIGALSGIPSWMELMIQKVIAYHKLDNIHEIWPNLKVFTSGGVAFGPYKKSFQALMGKPVIVIDTYLASEGYIATQVRPETDAMQLNTDSGIYFEFVPFKPEYINKDGSLVADAPSITLKDVQLDKEYVLIISTVSGAWRYLIGDTITFTDVARAEIKITGRTKFFLNTVGSQLSVNKMDAAMRELEDEFETTFPEYTICAKRGEDGEFYHFWYLGSELENPDESKIANYLDEALKSSNKNYKVARGKALKGVKVKVIAPERFHNWSAKNKKKGGQVKMERVMDEEKFAEWEAFLEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMS2</accession>
    <name>A0A5C6ZMS2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06985</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="155" mass="17770" checksum="E088399F1485C5B4" modified="2019-11-13" version="1">MNKFSKVLAFVAVSAGIAYLTRKWMSRSYSKLKDSSDASDAGYSVETNHQNLRDINHSNRSSDPTDNYGSNASARTSDYSNSRTQRMYKDLGMTKAQRRRYEADYSAIMDGWEKDNPERKMDGKTKVDQHNATLNAVLNEAQYSIYREWSEKNPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMU8</accession>
    <name>A0A5C6ZMU8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07095</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_040556273.1">
        <property type="nucleotide sequence ID" value="NZ_VORO01000005.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="38"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="103" mass="11788" checksum="1762DC458647B257" modified="2019-11-13" version="1">MKTYSLDEVTDKYIGKKGTPKRDEFENELRLDLIGNAIKQARKERNLTQAQLGELVGVQKAQISKLENHLTDARFETILKVFKALNAKINFNVELLNQNLNLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMY5</accession>
    <name>A0A5C6ZMY5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_04770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="130" mass="14122" checksum="76069FF02C96299A" modified="2019-11-13" version="1">MLSSQAQESIKSLRSSQKAPTGKETSQFQNYISVKGNVSEGDTVLPGVNVVLEGTTKGTSTNFDGDFEFPDQLKVGDVLVFSYVGFASQKVIIENKDSASKIDLKIDMKMDSCIIMGKVAVKEVYKSVKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN38</accession>
    <name>A0A5C6ZN38_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Gliding motility lipoprotein GldB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">gldB</name>
        <name evidence="1" type="ORF">ESY86_01980</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019853">
        <property type="entry name" value="Motility-assoc_lipoprot_GldB"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03514">
        <property type="entry name" value="GldB_lipo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="319" mass="37095" checksum="119382043622F430" modified="2019-11-13" version="1">MRLIYVFAVLLLLCLGCKNDDSGENKISKIEMNVSIERFDRVFAKAKPRDLESIKKTYPFLFSKQVEDTVWLERMKDTLQQQLFEEVDAQFGDFKQTEAEITSLFKHIKFYDKSFTAPRVITLTNDVDYRYPVVVTDTIVLLALDNYLGSAHEFYANIPAYITANMTKSQIVVDLAAEYAKRNSHQSLKKTLLDEMIYFGKQMYFKDKVIPFKTDAEKIGYTPKQLEFAIENENMIWTYFVNKEVLFSTDVALSARFIAEAPFTKFYLDIDNETPGRLGQYIGWQIVKAYMTNNTVDLNTMMDTDALEIFNKSNYKPEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN54</accession>
    <name>A0A5C6ZN54_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_01455</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="123" mass="14237" checksum="9F26E75387C36907" modified="2019-11-13" version="1">MRSLLKYKFGHVQIHDNFVIVIVNEGEVVDKLKNTVLVDIAQSYFKDRPFVYITHRINSYAVDPSVYEATSRIKNLIGFCVVSSNFLAKNNAQVEKLFFNKPFEVFENLPEAINWSNALIEKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZND7</accession>
    <name>A0A5C6ZND7_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA mismatch repair protein MutL</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 7" type="primary">mutL</name>
        <name evidence="7" type="ORF">ESY86_00665</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the DNA mismatch repair MutL/HexB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032300">
        <property type="term" value="C:mismatch repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1540.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00149">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014762">
        <property type="entry name" value="DNA_mismatch_repair_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020667">
        <property type="entry name" value="DNA_mismatch_repair_MutL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002099">
        <property type="entry name" value="DNA_mismatch_repair_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013507">
        <property type="entry name" value="DNA_mismatch_S5_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038973">
        <property type="entry name" value="MutL/Mlh/Pms"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014790">
        <property type="entry name" value="MutL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042120">
        <property type="entry name" value="MutL_C_dimsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042121">
        <property type="entry name" value="MutL_C_regsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037198">
        <property type="entry name" value="MutL_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073">
        <property type="entry name" value="PTHR10073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01119">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08676">
        <property type="entry name" value="MutL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01340">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00853">
        <property type="entry name" value="MutL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118116">
        <property type="entry name" value="SSF118116"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00585">
        <property type="entry name" value="mutl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00058">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3 4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="7" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_mis_repair" evidence="6">
        <location>
            <begin position="209"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="MutL_C" evidence="5">
        <location>
            <begin position="433"/>
            <end position="575"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD91135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="616" mass="69310" checksum="1EBB3B5737288D04" modified="2019-11-13" version="1">MSDIIQLLPDHVANQIAAGEVVQRPASVVKELMENAIDAAATHIKLVVKDAGKTLVQVIDDGHGMSATDARLSFERHATSKIKSADDLFSLNTKGFRGEALASIAAIAHVELKTKRSQEELGTQIEIEGSEIKAQEVTVTPKGTAIAVKHLFFNIPARRNFLKSNTVELRHIIDEFHRVALAHPDIAFSMFHNGSETFNLPKSNYRQRVVNIFGVKTNEKLVPVEEETEVLKISGFVGKPEFAKRSKNEQFFFVNNRFIKSPYLNHAINSAFDGLLKDGSHPSYFLNLSVDPKTIDINIHPTKTEIKFDDEHTLYAIVRASVKHSLGQFNIAPVLDFERDRNLDTPYDYQNKRASTPSVEVDRNYNPFQEEQNFNKRSLAKPFKKESAQWESLYVGMESKGTKTGSNFSQVEFESQPESQGLFNDASAESRQTTYQLHNKYIISTIKSGMMILDQNRAHQRVLYEGLLRSLTVREAVSQQLLFPLQLQFSTSEMEVLQELKEDLEHTGFLFSEFVKGNVEITGVPINVAESEVAIILEQLLSDVQQEVPDTNFSAMDLMAKSMAKSLAIKTGQSLTRMEQEHLVNSLFACKEPSVSPTNRVTFITMSVDDFDKKFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNH2</accession>
    <name>A0A5C6ZNH2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA polymerase sigma factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_00155</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="12"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="3">
        <location>
            <begin position="109"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD91047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="168" mass="19818" checksum="282D2024A9C7A6B5" modified="2019-11-13" version="1">MRKSKNEAFETMYRQHHSMVLQMCLGFVEGDKDTANDLSQEIFISVWNNLDKFRGASSYKTWIYRITVNTCLQYVKKDRKETPLSKSEIENQTTDKDEEKPKFDDIPKLYSAIGQLKKIDRLIIMMVLENQDYISISEVIGIKPINVRVKIHRIKKRLEKILKNNTDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNQ5</accession>
    <name>A0A5C6ZNQ5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Class I SAM-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_04500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="218" mass="25299" checksum="BC683D69AF87CCFA" modified="2019-11-13" version="1">MDYNNKPETYYKFPRPEMLEFLPKEAQCVLDVGCGQGTFGGQIKNLNNAEVWGIEYMPNEGEMAKSILDKVFIGAVEDFLTDLPNNYFDVIYFNDVLEHLAYPDQVLKDLKPKLKSKGLIISSIPNMRYFRSFKKLVVNGDWDYQDHGVMDKTHLRWFTKKSIRKMYESIGFKILQHQGINPSGSIKPLLYNIPFCFTALDIKYKQFATVAQKIDLQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNT9</accession>
    <name>A0A5C6ZNT9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">TIGR00266 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_01210</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002838">
        <property type="entry name" value="AIM24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036983">
        <property type="entry name" value="AIM24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016031">
        <property type="entry name" value="Trp_RNA-bd_attenuator-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01987">
        <property type="entry name" value="AIM24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51219">
        <property type="entry name" value="SSF51219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00266">
        <property type="entry name" value="TIGR00266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="265" mass="28502" checksum="EE396C5FA76BCFDB" modified="2019-11-13" version="1">MNAHEIDYRIFGEEMQFVEVELDPQEGVIAEAGSFMMMDDGIEMDTIFGDGSEKDSGFFGKILGAGKRILTGESLFMTVFYNANTGKRNVSFASPYPGKIIPIDLTEFRGKFICQKDAFLCAAKGVSVGIEFSKKLGRGLFGGEGFIMQKLEGDGMAFVHAGGTMAKRVLQAGEILRVDTGCIIGFTQDIDYDIEFVGGIKNSIFGGEGLFFAKLRGPGTVYIQSLPFSRLAGRILASMPQGGKSKGEGSVLGGIGNLLDGDNRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNW8</accession>
    <name>A0A5C6ZNW8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Lysine--tRNA ligase</fullName>
            <ecNumber evidence="6">6.1.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Lysyl-tRNA synthetase</fullName>
            <shortName evidence="6">LysRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">lysS</name>
        <name evidence="9" type="ORF">ESY86_01770</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6 7">
            <text>ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys)</text>
            <dbReference type="Rhea" id="RHEA:20792"/>
            <dbReference type="Rhea" id="RHEA-COMP:9696"/>
            <dbReference type="Rhea" id="RHEA-COMP:9697"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78529"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6 7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6 7">Binds 3 Mg(2+) ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.6" evidence="6"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004824">
        <property type="term" value="F:lysine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006430">
        <property type="term" value="P:lysyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00775">
        <property type="entry name" value="LysRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04322">
        <property type="entry name" value="LysRS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00252">
        <property type="entry name" value="Lys_tRNA_synth_class2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002313">
        <property type="entry name" value="Lys-tRNA-ligase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044136">
        <property type="entry name" value="Lys-tRNA-ligase_II_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018149">
        <property type="entry name" value="Lys-tRNA-synth_II_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00982">
        <property type="entry name" value="TRNASYNTHLYS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00499">
        <property type="entry name" value="lysS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="8">
        <location>
            <begin position="181"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="407"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD90716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="563" mass="64397" checksum="0714EEA1800C6869" modified="2019-11-13" version="1">MQLSEVELVRREKLAKLRELGINPYPAESFEVDHTAAQIKEHYEEGKKTIIAGRLMTRRIQGNASFAELQDSTGRIQVYFNRDEICTGEDKSKYNEIYKKLLDIGDFIGIEGELFTTKVGEKTVMVKDFTLLSKALKPLPQPRVDAEGKVHDAFTDPEQRYRQRYADLVVNPKVKDVFIKRSKLFTAMRDFFNDSGYFEVETPILQPIPGGAAAKPFVTHHNSLDIPLYMRIANELYLKRLIVGGFEGVYEFSKNFRNEGMDRTHNPEFTAMEIYVAYKDYNWMMDFCERLLEHCAMAVNGTTKATYGEHHIDFKAPYARVTMADSIKHFTGFEITGKTEAEIRQAAKDMNISVDDTMGKGKLIDEIFGEKCEGNYIQPTFITDYPKEMSPLCKEHRENPELTERFELMVCGKEIANAYSELNDPIDQRERFEAQLKLAAKGDDEATAFIDEDFLRALEYGMPPSSGMGIGMDRLIMFLTNNQSIQEVLFFPQMRPEKKQVELSENEKEVFQLLKGNSPMDLNALKAESGLSNKKWDKTIKGLTAKKVVNVAKNDEGLFVEML</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZP27</accession>
    <name>A0A5C6ZP27_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="10">MotA/TolQ/ExbB proton channel family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ESY86_02100</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the exbB/tolQ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002898">
        <property type="entry name" value="MotA_ExbB_proton_chnl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01618">
        <property type="entry name" value="MotA_ExbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023001088" evidence="8">
        <location>
            <begin position="22"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="170"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="211"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="MotA_ExbB" evidence="9">
        <location>
            <begin position="128"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD90776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="271" mass="29099" checksum="3929C77FD6AF5C92" modified="2019-11-13" version="1">MKRLFSILAIATIMASGTVNASTNAFTVETATSAAVATPFQDATEEAATTADTELSFTQQVKERFIEGGPFFMGIVLLTLILGLAICIERIIYLNLATTNTKKLTQDVEDALNSGGVEEAKEVCRNTKGPVASIFYQGLDRADEDIDAAEKAVVAYGGVQMGQLEKNVSWISLFIALAPMLGFMGTVLGMIDAFDKIEAAGDMNPSLVAGGIKVALLTTVFGLIVAIILQIFYNYIIAKIDSIVNDMEDASITLMDLLVRYKVKTTKTVIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPA9</accession>
    <name>A0A5C6ZPA9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Bacillithiol system redox-active protein YtxJ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ytxJ</name>
        <name evidence="1" type="ORF">ESY86_00865</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022551">
        <property type="entry name" value="BrxC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11009">
        <property type="entry name" value="DUF2847"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04019">
        <property type="entry name" value="B_thiol_YtxJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="130" mass="14556" checksum="328DD77EE18BFE9D" modified="2019-11-13" version="1">MGFLNSIFGSSESSGSKEVKELPWLALTDKQQLETIEAQSKTKTQVIFKHSTTCGISRMAMKQFVSGYDMDANLDLYYLDLLSYRDVSNAIAEKFQVMHESPQMLVIKNGTTVAHASHSAINDLVLEKFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPF9</accession>
    <name>A0A5C6ZPF9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bifunctional oligoribonuclease/PAP phosphatase NrnA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_04010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001667">
        <property type="entry name" value="DDH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038763">
        <property type="entry name" value="DHH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003156">
        <property type="entry name" value="DHHA1_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01368">
        <property type="entry name" value="DHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02272">
        <property type="entry name" value="DHHA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64182">
        <property type="entry name" value="SSF64182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHH" evidence="1">
        <location>
            <begin position="18"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="DHHA1" evidence="2">
        <location>
            <begin position="246"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="339" mass="37800" checksum="E1217403B31C6B20" modified="2019-11-13" version="1">MDKHAISSIKSLLSTPKHIVIVPHKNPDGDAIGSTLALCHYLKLHNHHAVVIAPNDYPDFLKWMPGENAILKYDSQKQDCDQDIEKSDIIFTLDFNALGRIGAMENVITASEAKKIMIDHHQQPDDYADFMYSDVTMSSTCEMVFNFIEMLGDVDKIDKAIASCLYTGIMTDTGSFRFSSTSSNTHKIIGKLIETGISNSEIHNNIHDSNSYERMQLLGCALSNLKVIPEYQTAYITLTQEELNTFNFKKGDTEGFVNYALSVKGVIFAAIFIESHQDKIIKISLRSKGDFSVNDVARTYFEGGGHTNAAGGKSDLSLKETIEKFIGILPHYQKDLKTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZQ20</accession>
    <name>A0A5C6ZQ20_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Biopolymer transporter ExbD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_02085</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ExbD/TolR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003400">
        <property type="entry name" value="ExbD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02472">
        <property type="entry name" value="ExbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD90773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="159" mass="18042" checksum="8FD9DC0C558B0D59" modified="2019-11-13" version="1">MSKFKSKKDNALPAMNTASLPDIVFMLLFFFMVVTVMREDTLLIENILPVANQVEKLDKKYPISYIYMGQPAKGYEKFGEAARIQLNDKFAEISEVQSFINAERLALREEMIPYLTVSLKVDKDANMGVVMDVKQELRKANALKINYTTGTGDVSQNMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZQB6</accession>
    <name>A0A5C6ZQB6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">T9SS type A sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_02520</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022833901" evidence="1">
        <location>
            <begin position="21"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="Por_Secre_tail" evidence="2">
        <location>
            <begin position="306"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="368" mass="40897" checksum="45512463D7C26745" modified="2019-11-13" version="1">MQKKDLIYAILLLFSCTAIAQENLLCPLLVDVVKIQQPAYIPIITNNTDGTVALSFPDQAITTIFAAYSIYDFYQSYPNSNPDGELFKYYSIAHDNKNLITELDTNVASDIFTFDLSYSTTPISANLIDLLDGKTYELMQYCNNSTESGENCENSTYNVPEGFELQIDFGYDSENDMITAATSSLSPCGNAFAIGMKGGFDDSSAALDNTLQLWTTTEGTSSASESSDPCFQIELMLYSMLDIGCIAYNYGNLSVNQNDENGQVILERENGTFSTDYMIFEEANLSVATETFSKMTPFQAEGNPYLQIRNAENQALNIEIFDLSGKRVLAETGFENDKINLSTYTNGLYFIKLSNLNNAQKVFKFLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZQY2</accession>
    <name>A0A5C6ZQY2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aspartate aminotransferase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_01595</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="1 2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD91303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="437" mass="47668" checksum="F3E1D4E00F668C0D" modified="2019-11-13" version="1">MIKKLTESQDLFERRKKIVANGVGVFNTATVKDAKGAIIIDADGHELIDFAGGIGVVNAGHCPEPVVAAIREQAGKYLHTSFNVVTYEPYIALCEELAEILPHGEKTKVMLVSTGAEAVENAIKIARQATNRPAILCYTDAYHGRSMMAMTLTSKVSYKYDCGPFAPEVYRLPFPNFYRYHGTRTMEEFVEDELKRLHESALNLVDVKNVAAVIIEPIQGEGGFNPVPQKYLEGLRAFCDTHGIMLIMDEVQSGFCRTGHWASWQHYDVQPDISTYAKSLGSGLPIAAVVGRAEVMDAAAIGSIGGTYIGSPICCVAASATIKFMKEINLNDKAVKIGHVIMNRLQGLMKQHAEIGDVRGIGAMIGIEFVKKDDRKQPNSEICSHIVKGCADNGLIVLSAGTYKNIIRILSPLVITEVELEKGLSILEAEISKAIQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZA95</accession>
    <name>A0A5C6ZA95_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Outer membrane beta-barrel protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_19200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000037">
        <property type="protein sequence ID" value="TXD86820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027385">
        <property type="entry name" value="OMP_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13505">
        <property type="entry name" value="OMP_b-brl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022846363" evidence="1">
        <location>
            <begin position="23"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="OMP_b-brl" evidence="2">
        <location>
            <begin position="9"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="312" mass="33827" checksum="594DBE18C29FA65E" modified="2019-11-13" version="1">MRIIPKIFIAAMVASTGYMAQAQDDPSMNNTTNGFYLRVGGGYAFESGKTEFNNADPNGLTGIMQSTDVTVNADGSSVNVKSLNGTVGAGIKLNLTAGYMFSPYIGAEMGFSYFHGDETMIGRLRSPEVTSEENIYLRGVDLAPAIFLTPNFKKFNPYTRIGLIIPVAGQLNIETMARQVNGGGQGTDLMIEAKSEVKSRFSVGYFGALGVTYPINDKLSLFGEIEIKNLSIESKTAEITEYRTTAITNGQSQLVPGQQLADLPVYEKKFEFTDDFDQSTTTPPNQDAARKIPTQFVNASGTGINVGIRYLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAG2</accession>
    <name>A0A5C6ZAG2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_20510</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000081">
        <property type="protein sequence ID" value="TXD86213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="86" mass="9813" checksum="E313A80512842285" modified="2019-11-13" version="1">METILSFARSTIPVNEKMLVENTNIGSSTTNETSTQVYGFKASRFENKQARFKRDSDSSKAIVGVFHQQSQQSETKDDLNRNYLFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZB96</accession>
    <name>A0A5C6ZB96_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">IS3 family transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000108">
        <property type="protein sequence ID" value="TXD85940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025948">
        <property type="entry name" value="HTH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13276">
        <property type="entry name" value="HTH_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13333">
        <property type="entry name" value="rve_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="124"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD85940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="298" mass="34923" checksum="A92642F4A72F70EF" modified="2019-11-13" version="1">MDAIHGKHRCSKTKIIKMVGIVESSYYREPGGGKKGNKPSTHTFHDSRGLVSQDTVVASVKDFLRHEFIDCGYRLMTSYLKRDGYVINHKKLYRIMKEEGLLKLDDRIDRSGSGRKFVKFRKVHTNRPLQCLEMDIKMVWIPSVGKNAYLLSVIDVHTRRILKDYFSFNIKQDQVIALLSLLFEDYDYPDSVVIRSDNGSQFIAKKVREYLGMIGVQQEFTHVATPEENAHIEAYHGILKKEVFRRFDYHYFGEIEQILKRYVKFYNNRRLHGLLGRITPMEKWNADKHLIIMKKLTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBT0</accession>
    <name>A0A5C6ZBT0_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="11 12">Protein translocase subunit SecA</fullName>
            <ecNumber evidence="11">7.4.2.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11 17" type="primary">secA</name>
        <name evidence="17" type="ORF">ESY86_16985</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Monomer and homodimer. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cell membrane</location>
            <topology evidence="11">Peripheral membrane protein</topology>
            <orientation evidence="11">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="11">Distribution is 50-50.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 11 12">Belongs to the SecA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.4.2.8" evidence="11"/>
    <dbReference type="EMBL" id="VORO01000024">
        <property type="protein sequence ID" value="TXD87473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017038">
        <property type="term" value="P:protein import"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd18803">
        <property type="entry name" value="SF2_C_secA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01382">
        <property type="entry name" value="SecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000185">
        <property type="entry name" value="SecA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020937">
        <property type="entry name" value="SecA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011115">
        <property type="entry name" value="SecA_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014018">
        <property type="entry name" value="SecA_motor_DEAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011130">
        <property type="entry name" value="SecA_preprotein_X-link_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044722">
        <property type="entry name" value="SecA_SF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011116">
        <property type="entry name" value="SecA_Wing/Scaffold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036266">
        <property type="entry name" value="SecA_Wing/Scaffold_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036670">
        <property type="entry name" value="SecA_X-link_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30612">
        <property type="entry name" value="PTHR30612"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07517">
        <property type="entry name" value="SecA_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01043">
        <property type="entry name" value="SecA_PP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07516">
        <property type="entry name" value="SecA_SW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00906">
        <property type="entry name" value="SECA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00957">
        <property type="entry name" value="SecA_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00958">
        <property type="entry name" value="SecA_PP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81767">
        <property type="entry name" value="SSF81767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81886">
        <property type="entry name" value="SSF81886"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00963">
        <property type="entry name" value="secA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01312">
        <property type="entry name" value="SECA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51196">
        <property type="entry name" value="SECA_MOTOR_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 11 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 11 12" id="KW-0653">Protein transport</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-1278">Translocase</keyword>
    <keyword evidence="9 11 12" id="KW-0811">Translocation</keyword>
    <keyword evidence="2 11 12" id="KW-0813">Transport</keyword>
    <feature type="domain" description="SECA_MOTOR_DEAD" evidence="16">
        <location>
            <begin position="5"/>
            <end position="770"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="14">
        <location>
            <begin position="179"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="15">
        <location>
            <begin position="617"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1025"/>
            <end position="1048"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="1028"/>
            <end position="1048"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="177"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="195"/>
            <end position="199"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="692"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="TXD87473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1117" mass="127375" checksum="0DB29E00A8933F59" modified="2019-11-13" version="1">MSFLDSVLKVFVGDKSKQDVKSLSPIIDQVKAFESELEGLSHDGLRAKTAEFKTIIAEARQPLQDRIDELLKKAEASEDIDEREEYYEEIDGIKDNIYTVTENVLNDIMAEAFAVIKETAKRFVKNTELHVQANEFDREVSGAKDYVTLNGEQAIWHNSWDAAGKPITWDMVHYDVQLIGGVAMHQGKIAEMQTGEGKTVVATLPMYLNALSGKGVHLVTVNDYLAKRDSAWMAPIFEFHGMSVDCIDYHRPNSAERRKAYQADITYGTNNEFGFDYLRDNMAHSPDDLVQRPHHFAIVDEVDSVLVDDARTPLIISGPIPQGDRHEFTELKPKVDDIVTIQRKHLTGVLAEAKKLIAEGDTKEGGFLLLRAFRGIPKNKALIKYLSVEGNKLLLQKTENHYMQDNNREMPKVDADLYYVIEEKNNQVELSDKGVEYLSGKDNPDFFVMPEIGIEISKIEAQNLSKEKEAEAKEELFREFGIKSERIHTLNQLLKAYALFEKDIQYVVMDNKVMIVDEQTGRIMDGRRYSDGLHQAIEAKENVKIEDATQTFATVTLQNYFRMYRKLAGMTGTAVTEAGEFWEIYKLDVVEIPTNRPIARDDKQDLVFKTKREKYNAVIDEVTNLSQAGRPILIGTTSVEISELLGKMLSIRKVPHNVLNAKLHKREADIVAEAGQPGQVTIATNMAGRGTDIKLVQKVKEVGGLAIVGTERHDSRRVDRQLRGRAGRQGDPGSSQFYVSLEDNLMRLFGSERIAKMMDKMGLKEGEVIQHSMISKSIERAQKKVEENQYGVRKRLLEYDDVMNAQREVVYKRRHHALFGERLSVDLANMIYDTSEGITETNKGATDYKNFEFELIRYFSMSSPVTAAEFEKLSVQDISGKVYKAAYEHYKAKMQRNAELAFPVIENVYLNQRDKFKRIVVPFTDGVKNLQVVTDLEKAYETKGKQLINDFEKNITLAIVDDAWKTHLRKMDELKQSVQLAVHEQKDPLLIYKFEAFELFKQMIDEVNKDVISFLFKGELPSETQNSIQEARERKQEKFETQKDEIPNMDERAAQSRAAGGNTQRQQEVVETIVRDKPKIGRNDRVTIKHVMSGENKTVKYKQAEPLLDKGDWVLVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBX4</accession>
    <name>A0A5C6ZBX4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">T9SS type B sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_16680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000023">
        <property type="protein sequence ID" value="TXD87529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026341">
        <property type="entry name" value="Bac_Flav_CTERM"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04131">
        <property type="entry name" value="Bac_Flav_CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023140047" evidence="1">
        <location>
            <begin position="22"/>
            <end position="1607"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1607" mass="175307" checksum="E2B9FF8FFD8BCB9A" modified="2019-11-13" version="1">MVFLKKTLIALICLYGSASLAQQITVDNSFTAEALITNNLVVGCVETSNVVSDFNGSVNGFNSYAYFEKGSSEFPFENGIMLSTGNPMSGGNTLNNTILNEGNDDWIADPDLESALGISNTLNATSISFNFTSITDRIQFNYILASEEYFGNFPCEYSDGFAFLIKEAGSSDPYVNIAVIPGTTTAVNTNTIHDEIVGYCPASNAAYFEGFNVGDTNYNGRTTVMSATAAITPYTQYSIKLVIADQTDKNYDSAVFIEGNSFNSNVDLGEDITTCASNVTLEGDISNPQATYAWYLDDVLIPGEITSTIQAIASGIYKIEIQIPLAGSNCVIEDSVAISLSSTQSAEAITDYQLCDDNGNSREIFDLSIKDAEVLDAVPNSSYVISYHYTSASAENNSNPIVTPIENTSNPQSIFVRIEDSLNGCLAYSSFQLKVNALPVVTTPTVFVACAEVDAGGSAIIDLSEKDEEITGGNPDLNVTYYLDPLDAENGVNAIPLPYVNSNANEQVYVRVTNTVTGCVSTTTLTIEVINKPVINAGLHMIDACDQDHDGFAFFDLTTITDDVLQGLTGVNVTFHQTLEDANLGANAIADATNYANVVADDSVVFIRVEDQNTGCAAITAIEIHTNLLLTGTDIKKVTQCDIDNDGQESFDLGGIALDIINGLEDVTIDFYLTEEDRDTNTNPLDPTVSFVPTSNPQFLYITLSNPTCSEVAAIELIINPVIEGVAIGSQLVCDEDQDGFTSLNLNQFNDVITAGQPGFNVKYYLTEEDAINNSGAVPSSYTNISNPQLFYYRARFNQTGCADVKAFEVTVLEAPISAAPTGIIICDADQDGFSIVNLNAKIPEVISNTANRAVTFHTSVADAETDSNPILDASNFNAQTQDLTVRIENVSTGCYSLQNLEIIVNTLPVINPISVYKFCEVGDDGFGEFVFSSQDADILEAQTGKVVFYYETAMDAENNTNAIDKNDVYVNSSNPQTIHIRIENISDPSCYAVSSFPIEVGTNPDFNEATDIFVCDDITNDGSVMFDLSIQMGEITAGIQDIEEVTLHASQQDAINNVNPLPLDFENNVNPQQIYARINNGSICESYTSFVLNVIAAPDVNIPDPLEQCDADYDGITSFDLTLSTLDILDVRQDNIEVGYYRTQADAVLESNEITDPANFTNTSNPQTVYVRVSNTISNCFVNVPVGLIVNRPPTINFIDNYNICATEDQRTDLTEINSSLLDQTANVLVNYYASEEDARNQTNVLDNNYNYQSNNDLLFARVEFSTTHCFIIHDFNLKVNALPVANQPSDMAACDDDFDGFLNFDLSTQNSSILGGQNPNNFEITFYTDVVFAQEGVADIGTIYEGINNEIIYARLENKFTDCYEITQFTLIIYERPIVNIDNQVICLENLPLVVSANTNITGDSYLWSTNASTPEIEITEVGSYSVTVTSAFGCETTQVFSVIESEAANIEVTEVIDFSDPNNVTVTVSGIGNYLYQIDDLEPQESNFFESVPLGYHILTIIDLNGCSRVSKEIVVIDAPKFMTPNGDGYFDSWHITGVETLQGTVIFIYDRYGKLLTKLTANSEGWDGYYNGQKMPAADYWYLAQVKKNSIEFEVKGHFAIRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCC1</accession>
    <name>A0A5C6ZCC1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15935</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000021">
        <property type="protein sequence ID" value="TXD87650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="208"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="256"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="313" mass="34727" checksum="22F58E2CDC7413DD" modified="2019-11-13" version="1">MQLYKSRGFGEFFQDTFAFLKLNGSHLFKNFFIVNGIFLLILLVLGYFSTKFYSDVVLGGILNGNTAGIDNYMNENAGLFVIFIVTFVIMGLFAGIIAYAYVPIYMQLYAAHEGNSFGVKEIVNTYKANIGNIFIFLLCGIVVAIPMVIIVGIMAVVLTITIVGILALPLLVGAVSLFYQMTLMEYIKNEKGIWECFGYSWTLIVSKFWAAISCVGLFYLMSYIVQNIIAFIPYIFGMVSLFTEVEDGNSPNSAELGATMTVMMMAVFFLTFLVSSVLNVVLQSNQALIFYSLKEDIENINTKSVIDQIGAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCQ2</accession>
    <name>A0A5C6ZCQ2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ATP-binding cassette domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_19160</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000037">
        <property type="protein sequence ID" value="TXD86813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="25"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="250"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="7">
        <location>
            <begin position="29"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="337"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="370"/>
            <end position="377"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD86813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="551" mass="62567" checksum="5581668D5CE957A6" modified="2019-11-13" version="1">MKKIMTPWQRFINVLKLDKRDIKQIFYYAIFAGLVALTLPLGIQAIINLIQGAQVSTSWIILVVLVTLGVAFQGILELMQIRILENIQQKIFTRSSFEFAYRFPKIKFSEMHQRYPPELANRFFDTLMIQKGLSKVLLDFPAAILQIVFGLILLSLYHPFFIIYGLLLVILVYIVFKFTARRGMETSLKESKNKYAVANWLQEIARSLTSFKLSGRTSLAMERNNALTDKYLEARENHFQILMQQFIQMIGFKVLVTAGLLLIGGLLVLNQEMNIGQFVAAEIIILLVINSVEKLITGIESFYDVLTSLEKIGEVVDKELESQEGTDPFEFKSTASISFDRIAFTDMNGNLILDSLSLDLVPTDRLYVDGPSGSGKTTLLKLLSGLIETTEGAIYINDYNFKGMRINAYRSHVGQVIPEQMPFEGTILENITFGNKDIPIDTVNRVIKDIGLQKFVRSQAKGIDSPIFSQGQSIPHTVSKRLLLARSIVHDPKILLLKDALEHFEPQEARDLMEYLAHRDRPWLLIASGQNEDWKSVCNKTLNLNQDPFTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCX2</accession>
    <name>A0A5C6ZCX2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">IS1595 family transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17465</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000026">
        <property type="protein sequence ID" value="TXD87349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024445">
        <property type="entry name" value="Tnp_ISXO2-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12762">
        <property type="entry name" value="DDE_Tnp_IS1595"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS1595" evidence="1">
        <location>
            <begin position="23"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="147" mass="17079" checksum="CFC17EB8FAD50DC8" modified="2019-11-13" version="1" fragment="single">SNVMVMAESTVLEDIDTGKVERQCRYFKAKVLDDHKAEGTDQSFVDAIDGERTIVFTDKCTSYVNIADYVEIHVTEKSNEQTTKETLKWVHIAISNAKRNFTGTYHKIKKKYLQLYLNEFVYKLNRRYFGERIFDRLVIASITANGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD05</accession>
    <name>A0A5C6ZD05_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_17055</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000025">
        <property type="protein sequence ID" value="TXD87380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="144" mass="16504" checksum="32F461626502D487" modified="2019-11-13" version="1">MNFKRTTIIPLDDAELAKQLFDAYLNKEFMILMIILGDTDSIRKALPKADNLATKSYYGMERWVLWIRNHDVLESTLRPLLETNEQDETLVYEDVKCFSTSPILDAATGVILKNAELNYLSLQRSFFKAQSHDTGLINDVNNSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD85</accession>
    <name>A0A5C6ZD85_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sodium:solute symporter family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_18055</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000029">
        <property type="protein sequence ID" value="TXD87132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="75"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="114"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="175"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="229"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="266"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="293"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="356"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="381"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="410"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="444"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD87132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="487" mass="53318" checksum="A4FE0E96EBBA043A" modified="2019-11-13" version="1">MSRSAIIILFLVLYVALIIGIGLWNRRNDSSEEYFLASRNLPAWLLAITFIASWWGGGSAIDLVNHAHQNGLSSFWIYGVPVLIATALMYLFAKGIRNVGSISQPQLMKQRYNGHAALLLSIFIIIFMVIAASVQVIVIGRFFNAFFDVSYSVGALIGTLIVLSYSLFGGFKGVVLTDFLQFLFFLFTGVFLCYLTYSQSGGMEAVEAKALAMGKTGFTDFFSDVSNNLAYVITFGTSWMIQANIWQRISAAKKATDARKMMLISFFAFIPLYLMVTYTGMFSSVIYDSVPEAGIVPTLISGIANPILSAVLFLGLCSAMMSTMDSLINTGALSLTVDVYKPYINPNSTPKQEVRIGRISTFLLAALALLIALKIQSVLTISWIGSDFLTSGAFVPLVLGFLWARGTSKAAVYSMIFGLLFSSYNLLVALGVDLPVAWEIASATQALIGISASLLIYVMCSLFTLDDFEKNQRFIKKANILNRKALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDE4</accession>
    <name>A0A5C6ZDE4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Y1_Tnp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_16585</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000023">
        <property type="protein sequence ID" value="TXD87540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002686">
        <property type="entry name" value="Transposase_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036515">
        <property type="entry name" value="Transposase_17_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01797">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01321">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143422">
        <property type="entry name" value="SSF143422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Y1_Tnp" evidence="2">
        <location>
            <begin position="7"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="207" mass="23735" checksum="E0288FBC286F0B44" modified="2019-11-13" version="1">MKGYDYSRNNLYFVTICVDQMKCCLGQVVDADLIDENHPVGTGRDLSVHSDSKNNPVGTGRDLSARRADAVHPQLKKSKEFSIVPSRKVMELNAYGKIVEERLQWLAGQYQYVVLHNYVVMPNHVHAIIEINKHLVTEVGIKIKSLSELVGAFKSTSSKWIHELNFPGFKWKRSFHDSIIKEDRAHSMISNYISENPNKWINDKFYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDH6</accession>
    <name>A0A5C6ZDH6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">VacJ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_18025</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000029">
        <property type="protein sequence ID" value="TXD87126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="114" mass="13598" checksum="C57564F2220F403F" modified="2019-11-13" version="1">MILLPTINRSVLLVIPKQPFYDWSNKLFPDLEPTNMADIDEYNSYLLEDELFIDDPKGELKSYWKKIFLNELYEQCMDETTFPALSWKLFTQWFDFHRSAVVSDLTSDPLYTDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDS8</accession>
    <name>A0A5C6ZDS8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">N-(5'-phosphoribosyl)anthranilate isomerase</fullName>
            <shortName evidence="4">PRAI</shortName>
            <ecNumber evidence="2 4">5.3.1.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">trpF</name>
        <name evidence="6" type="ORF">ESY86_16365</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>N-(5-phospho-beta-D-ribosyl)anthranilate = 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:21540"/>
            <dbReference type="ChEBI" id="CHEBI:18277"/>
            <dbReference type="ChEBI" id="CHEBI:58613"/>
            <dbReference type="EC" id="5.3.1.24"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 4">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 3/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TrpF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.24" evidence="2 4"/>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00042"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004640">
        <property type="term" value="F:phosphoribosylanthranilate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00405">
        <property type="entry name" value="PRAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00135">
        <property type="entry name" value="PRAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001240">
        <property type="entry name" value="PRAI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044643">
        <property type="entry name" value="TrpF_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42894">
        <property type="entry name" value="PTHR42894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00697">
        <property type="entry name" value="PRAI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="PRAI" evidence="5">
        <location>
            <begin position="3"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD87629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="208" mass="23556" checksum="3BCF91ED6270711E" modified="2019-11-13" version="1">MKHPENILEVAALQPDYLGFIFYEKSSRFFNDLIPKLPKSIKKVGVFVNASVEHIVEKANIHELQAIQLHGNETPEFIKELVAQMERFFEQSLTIIKAFSIGDDFDFSVLQHFEDCCNYYLFDTKGKLPGGNGYAFSWTILNNYPSTKPYFLSGGIGLEEAELLNVFLKTEAAAYCYAIDLNSKFEIEAGRKDSKTLGVFKNKLIGSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDX5</accession>
    <name>A0A5C6ZDX5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">30S ribosomal protein S8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 6" type="primary">rpsH</name>
        <name evidence="6" type="ORF">ESY86_14900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uS8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01302_B">
        <property type="entry name" value="Ribosomal_S8_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000630">
        <property type="entry name" value="Ribosomal_S8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035987">
        <property type="entry name" value="Ribosomal_S8_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11758">
        <property type="entry name" value="PTHR11758"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00410">
        <property type="entry name" value="Ribosomal_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56047">
        <property type="entry name" value="SSF56047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD87955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="132" mass="14683" checksum="9112789D314230CC" modified="2019-11-13" version="1">MNTDPIADYLTRIRNAVKANHRVVEIPASNLKKEITKILFDQGYILSYKFVDSTAQGSIKIALKYNKDTKESVIKKIQRISKPGLRKYAGSNEMPRILNGLGIAIVSTSHGVITGKQAQRDNLGGEVICYVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE10</accession>
    <name>A0A5C6ZE10_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_18860</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000034">
        <property type="protein sequence ID" value="TXD86928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="86" mass="9521" checksum="3AF39869BECADC2B" modified="2019-11-13" version="1">MKTETLKIKVAQRVLGITDNRLLQKIQDVLDEENCFAYDADGHPVSKADYIESINVLNKDIGNGAAELHSTNDVLKCIANDHKLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE14</accession>
    <name>A0A5C6ZE14_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18175</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000030">
        <property type="protein sequence ID" value="TXD87060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022892030" evidence="1">
        <location>
            <begin position="25"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="226" mass="25670" checksum="020F213184D8D1E0" modified="2019-11-13" version="1">MSSTLPIKRLAFVLACLCGSFVFSQDLTETTIPEPQDAPQAQSARERKVALSFDLYRPSPSGNNFFAESASGSLGFNFDLQLFVYKQFFLGGGIGDSYFDNKDISKTGNYEKTTLSSHDFYVGYEFLPLEDFRLGVAVTIVGNSRYKNNQSNTRKVYQVDHGNLRNYQTYFAYEVDRTLSVFIKYTYRSDRTKIQVPSALNSYFEKTAVHQIGFGLKLYFGEKSVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE35</accession>
    <name>A0A5C6ZE35_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4347 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000025">
        <property type="protein sequence ID" value="TXD87369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025592">
        <property type="entry name" value="DUF4347"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045474">
        <property type="entry name" value="GEVED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14252">
        <property type="entry name" value="DUF4347"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20009">
        <property type="entry name" value="GEVED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="SSF50965"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="1">
        <location>
            <begin position="190"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1574" mass="163969" checksum="50D1B1ED0A2A9833" modified="2019-11-13" version="1">MKHLTTLKLIGFLILLLITSPVIHAHSLLSDDPLLDTKDDITSSIDPSVNVFIDKDVLQAEALLNTTLNHDDGVFHLFTHGKPGQLLIDGQWLQKEEIVSFINSKFNFPLGENSEGQRGLNIYGCNFAQGEKGQKAVAYLEKQLGITIAASTNVTGKDGDWQLESGTPTQLKALQNYAYNLQISCPNGLDVHIANDVSGSVNSTEFSQAKDFIAQLGASFDNDFGTLNTQSRISISNWSAGSNRFVEYDFPSAGQNYTTSIADILSYSSSSRPFGGQTDVYTALLRANEWVRQNPVSDRDVPKVIVLLTDASCSQVANNISSLATQIKNQGIYIVVLAIDDAASCTALQGINVASAGGYFSANNYNTLQQDAITFIQNIATASCDNGGPAFFDLTVSLSDFVITDCNTTAVASANYTVSNISSGDDFNANLQVSFYNGDPTQPETQYIFTDNAGTQNLANGMGTYSSTVNSDALINTSTLYAVVNFDGSLPGNAVPLSLSDLSNQINVANEGRTFNNISTPVTRDDGAGCQPFSTIDVQVSNSGVGCDDEVIYTLQICNTGTADALMSPSDIIPYAPAGFSLSSSTLIGTDPFDNLTGITASQLGQDIDGEALGDGSGASVSMSADGTTVAIGASANDVNGSNSGHVRAYHLSGGTWNQRGQDIDGEAAFDSSGFSVSMSADGNTVAIGAIGTDGNGSNSGHVRLYDWSGTAWIQRGLDIDGEAAGDSSGFSVSMTSDGNTLAIGARNNDGNTGIDTDNRGHVRIYDWAGGSWNQRGLDIDGEAAGDESGWSVSMSVDGNTVAIGATDNDSNGSKSGHVRIYDWSGTAWTQRGLDIDGENSNDESGWSVSISADGNTVAIGAIDNDGGGGSSGHVRVYEWSGTAWTQRGLDIDGEDNDDESGYSVSMSADGNTVATGAHRNDGNAFRAGHVRVYDWSGGSWTQRGLDIDGEAFGDYSGRSVSMSADGNTVAIGAPSNDGNGTSSGHVRVYSYGSGAEILPASTCATYEYTYNITGVAATAGTPYDYSLAVNASAQSGNDPVTFTPNTNFSADGNTGLNGFDGAVNNTDDLTYDGVTTPCTAGDQIAVSVSMTGDGSCPGSFSTATVTVENTSGTTISHALLTLDLSGTDAFYNGEPYNFTNGMVLEEPNIFDPAYPAVPNALSNQTGSQQLAIFALPDGTSTFELDVAVGTSVIDLSATIAQIPTNLNAGGSAIGSAGIAPAVEPSISGTPPGDVTTAATTIALSGYAATNATSVSWTSGSNGSFANASTASTTYTINDQDRAYGFVELSLEALSSGGCSTLTSFRVNITGGTYDYGDAQSSFDSGETQLPVAGAALISNDVFLGTIPADAEAAAQPTADATGDGADEDGLQTLTFGNFQPGNLYTLSVDATNNSAALAYLHAYIDWNDDGDFIGDEGEKSLLVNVPAGSGAATYEVNFIIPSNGAAFTSSTIVRLRLSSDEFAAGRSYGAAANGEIEDFLIDETLSVENLEAKGISIYPNPASDFLIIDFGQNAGRFNTVELYDITGRLMSKTSLKENPLDKVQVRIDQLNAGIYLLNLSSKEDQFSQRVIIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE73</accession>
    <name>A0A5C6ZE73_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SDR family oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_16925</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000024">
        <property type="protein sequence ID" value="TXD87462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="17"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="327" mass="35930" checksum="FAD1C76D8CD76BFB" modified="2019-11-13" version="1">MYDHKYHSEDLSKLNVLVTGGAGFIGSNIVEYLLKYKVNKVRVLDDFSNGHRENLSAFEQHPAFELMPGDIRDLDTCKAAMADMDYVSHQAALGSVPRSINDPATTNAVNISGFLNMMIALKDSKRVKRMVYAASSSTYGDSKALPKVEDNIGKPLSPYAVTKYVNELYAEVFGSTYNTDTIGLRYFNIFGPRQSPEGAYAAVIPLFMQALKDGIPPKINGDGEQTRDFTFVDNAVQANIRGLFASEAAKNQVFNIACGERISVNKLWDFLSEAAGKDLKPIYGASRQGDVRDSLADISKAETLLGYAPSFTVKEGLGVTWDSWVED</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE83</accession>
    <name>A0A5C6ZE83_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF420 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_14520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007352">
        <property type="entry name" value="DUF420"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37692">
        <property type="entry name" value="PTHR37692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04238">
        <property type="entry name" value="DUF420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="178" mass="20100" checksum="09F7C45B4C3AC3B2" modified="2019-11-13" version="1">MSKVETPSAEKKYNKWIVLLSVAIPIVVAVLFTVKIPNVEPLSFLPPIYASINGLTALVLIAAFVAVKNRKLKLHENLMKFAIGLSVAFLAMYVAYHMTSESTKFGGEGLLRYVYFFILITHILLSIVVIPFVLITYVRAITKNFERHKKIARITFPLWLYVAVTGVVVYVMISPYYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEC0</accession>
    <name>A0A5C6ZEC0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF1016 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_17980</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000029">
        <property type="protein sequence ID" value="TXD87118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009362">
        <property type="entry name" value="YhcG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041527">
        <property type="entry name" value="YhcG_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17761">
        <property type="entry name" value="DUF1016_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06250">
        <property type="entry name" value="YhcG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1016_N" evidence="2">
        <location>
            <begin position="8"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="YhcG_C" evidence="1">
        <location>
            <begin position="86"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="251" mass="28995" checksum="7D3BA45A1EB21FDF" modified="2019-11-13" version="1">MVQVSLAQNEKVQVSLAQIPWYHHISLLAKVKSIAERLFYVQETAINGWSRDTMLLQVKSNLYKRQGKAVTNFQQTLPVPQSDLAKQTIKDPYVFDFLTLKENFKEKDLENQLIEHVSKFLLELGKGFAFLGKQYHILIADQDYYLDLLFYHTILKCYVVIELKNTKFIPEYAGKLNFYLSALDDTLKQESDKPSIGILLCRDKNNVEVEFALRGMSQPMGVSEFNLTEVLPDHLKSSLPTVEELEKELEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEI2</accession>
    <name>A0A5C6ZEI2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Flippase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_16700</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000023">
        <property type="protein sequence ID" value="TXD87532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029303">
        <property type="entry name" value="Polysacc_synt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002797">
        <property type="entry name" value="Polysacc_synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01943">
        <property type="entry name" value="Polysacc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14667">
        <property type="entry name" value="Polysacc_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="81"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="170"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="253"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="293"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="332"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="361"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="386"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="Polysacc_synt_C" evidence="7">
        <location>
            <begin position="332"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD87532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="418" mass="47661" checksum="B4065AACE4DCD94F" modified="2019-11-13" version="1">MTSVFTKSDFIATKWFALEKIIQLIAGVFIVPQIFSALGSIDIGKLKFVESVLGLLTPLFFLGLSAICIRELVFHPKRDQLILATAFYLRMISWSVVFIGILIYFGLAEGTALSGLYLIIACSYLFKLTDVFEYYLLAKKWTKIIFISKISSLCIIVALQYYGVKNQFDVYYFAKLIVLDFCIQGLIYAIILKHKKQLDFKQWKFSWKLGASLLRMSFPLILSNGLVMFYIAIDELFLKYFYGDHENGIFASVQFLVIGLSWNIGFSIINALYPSLAESFQVNTALYRKKIKALLKIMLFLGVAIGGFYTIFGNTILETFFSETYKEAKTPLLIFSWAPLFIFLGMVYEKHLINTEALQKNVYRFGLGCLSNLILCYLLIPVWGVNGAAIAVLISHFITNIAYVFLDTESRKQVFSMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEJ8</accession>
    <name>A0A5C6ZEJ8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA polymerase III subunit delta</fullName>
            <ecNumber evidence="2">2.7.7.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">holA</name>
        <name evidence="2" type="ORF">ESY86_15065</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009360">
        <property type="term" value="C:DNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010372">
        <property type="entry name" value="DNA_pol3_delta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005790">
        <property type="entry name" value="DNA_polIII_delta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06144">
        <property type="entry name" value="DNA_pol3_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="SSF48019"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01128">
        <property type="entry name" value="holA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA_pol3_delta" evidence="1">
        <location>
            <begin position="20"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="336" mass="38349" checksum="FC1F883A673C7AC0" modified="2019-11-13" version="1">MDDVKTIVADIKKGQIKPIYLLMGEEPYYIDAISDFIEKNVLSEEERGFNQMVLYGRDVSVEDIESNAKRYPMMAERQVIIVKEAQDLSRTIANLERYAKNPQPSTVLVLNYKYKSIDKRKTLYKTIKKTGVVFESKKIYEDKVPSWINRVLSGQDYSITPKASQMLVEFLGNDLGKISNELNKLKIVLPKGSQITPEHIEQNIGISKDYNNFELRKAIGYRDTVKAFKIVNYFGENPKDNPMVVTVSLLFGFFASLLHLHGMSSRNPRDVATALKINPYFVDEYLTAARNFPMRRVSQVIATLREFDVKGKGVNSNAVPQGDLLRELLVKILAQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEM8</accession>
    <name>A0A5C6ZEM8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">mnmD</name>
        <name evidence="2" type="ORF">ESY86_17500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000027">
        <property type="protein sequence ID" value="TXD87231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016645">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008471">
        <property type="entry name" value="MnmC-like_methylTransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05430">
        <property type="entry name" value="Methyltransf_30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_30" evidence="1">
        <location>
            <begin position="140"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="228" mass="25716" checksum="C844C317F823F6B6" modified="2019-11-13" version="1">MQRKIIITEDGSATIQIEDWNEQYHSVHGAIQEANHVYIKHGLLFCSEALSAEKKGISLLEIGFGTGLNAILSLLTAEALKLHINYVGVEGFPVSSEELQQLNYVEQLQMDKHRFDRLHNCSWEEPHAISEAFTLTKKQLFFKDIAEVNAYDLIYFDAFGARVQPELWTEDIFKLMFDALRPNGVLTTYSAKGSVRRAMQAVGFEVERLAGPPGKREMLRAVKKGSGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEN6</accession>
    <name>A0A5C6ZEN6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">2Fe-2S iron-sulfur cluster binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_13260</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002888">
        <property type="entry name" value="2Fe-2S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036884">
        <property type="entry name" value="2Fe-2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01799">
        <property type="entry name" value="Fer2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47741">
        <property type="entry name" value="SSF47741"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="2">
        <location>
            <begin position="77"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="266" mass="29435" checksum="46A5B5EC985BF8DD" modified="2019-11-13" version="1">MKEDDKFKEEVNLDKLSDDENIILDAMGLNGSNRRKFLKQVSMFSLGLYASSIFTSEIFADTMKDLPENARVLLNEVMVNLRVNKVVKPITIDSRTSLLDALRERLALTGTKKGCDHGQCGACTVIIDGKRNLSCLTLAATCEGKEITTVEGLANNGEMHPMQQAFLKHDGFQCGYCTPGQICSSVALLEEAKNGEASYVTEDLKTIKSGLTLSEEEIRERMSGNICRCGAYNNIVQAFKEVHTGNEEMPTWEFATQEQMDNAKNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEP5</accession>
    <name>A0A5C6ZEP5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Molybdenum cofactor biosynthesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_13310</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008641">
        <property type="term" value="F:ubiquitin-like modifier activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="PTHR10953"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="SSF69572"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Rhodanese" evidence="4">
        <location>
            <begin position="253"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD88282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="336" mass="37123" checksum="420145CC7973DAA5" modified="2019-11-13" version="1">MRYDRQIKLDEVGVSGQEKLRNASVLIVGVGGLGCPAAQYLTGAGIGKIGLMDHDTISVSNLHRQVLYDENDLGKSKVLVAKEKLQRLNSEIELVAIEEALTIDNAEKLFSEYDLILDGTDNFETKYLINDACILAGKPWVYASIYKNEGQLSVFNYQNGPSYRCLFSKTTRQNVSCEATGVLGVVPGIFGMLQAMEALKIILGVGNVLSGKLKISNLLSGSEQILNIQKKPEEIEKVKKNGIMSVRMDCEMKDSDKKYLDVREEFEQPKVTAANVIHIPLGELQQRSNEIPEQEEVLVFCQSGKRSAKAVEMLQTDFGFQNLKNVEGGIKTIING</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF11</accession>
    <name>A0A5C6ZF11_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">T9SS type A sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_15195</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023061558" evidence="1">
        <location>
            <begin position="26"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="domain" description="Por_Secre_tail" evidence="2">
        <location>
            <begin position="773"/>
            <end position="850"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="852" mass="89414" checksum="41B5E01BA9DC1F49" modified="2019-11-13" version="1">MKNFTKLMIAGICGASSMLPSSASAFQGDSQDGCYATEVVASNQGLTSNGAAVPANRSDVSKTLMSPDMSNAVGGFYSLGMGGSITLKFGGAVSNSDGNDIMIYETSYSGDTCGASDDETAMIEVSQDGSTWYNLGNICRDGGVDLDGLPVPFVTQIRITDMTTNNGDGYDVDGVVAIGGCEPVSDVDLCYGSSIVEGSFQQGLQKNNQPVAGNRSDATKALGAPELIYDPNTVTYVSLGYGGSIVITFDGVVYDAPGDDLAVAETTGNNAGATAPWVETAEVFVSQDNVIFHSVGFANKFELAQFDIADAGVGLTFIRSVKVVDVTPMSSISADAYDLDGIIALNGCSQDPSQDPEVCENFDYFVADRQQNGGILKIYAAKIIGGNAVLTMITSRDPEVSIAYDEANNVLYGINAAGTLIEKIDPINGASLGFVNIAPGFGNQVFSAVFKNGILYTASGSQNRVIAIDVTDGSFTEVVADLPINGGDLAFIGNDLYISTKDGDDLYKFVGGVAVNVGSVPANVHGVSATPDGNLAVIAKNSNAIQFLDTNGNVTNSVPATLDGQPFTFKDGDMTGGCNIPFNADPNPSECYVVDYMNYIEGTTKNGGEVAEIRTNPDMVLGEPEGTDDYVFTTLGYGGEITLTFGGAIPNVPGPDLFFVETSFNKPLGCETYPEYADVYVSLDNVTYYMAGTICKSEATIDISDAGVLDYVNFVKVVNNNEMSTTPDGFDLDGVVALGTCVDFNIEAFLAQQSSALLSANSLEARDLGFISYPNPTSGVSNVEFVAKTSGKVLIEVYDINGRNIAQVFNGNTFAGQQYKANFDGSNLASGLYIYKITTNNTSISEKFIISK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF17</accession>
    <name>A0A5C6ZF17_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Isopentenyl-diphosphate Delta-isomerase</fullName>
            <ecNumber evidence="3">5.3.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_12985</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Isoprenoid biosynthesis; dimethylallyl diphosphate biosynthesis; dimethylallyl diphosphate from isopentenyl diphosphate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the IPP isomerase type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.3.2" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00059">
        <property type="reaction ID" value="UER00104"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004452">
        <property type="term" value="F:isopentenyl-diphosphate delta-isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050992">
        <property type="term" value="P:dimethylallyl diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02885">
        <property type="entry name" value="IPP_Isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00202">
        <property type="entry name" value="Idi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011876">
        <property type="entry name" value="IsopentenylPP_isomerase_typ1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018427">
        <property type="entry name" value="Isopntndiph_ism"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02150">
        <property type="entry name" value="IPP_isom_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="7">
        <location>
            <begin position="29"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="66"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR018427-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD88427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="175" mass="20822" checksum="DE091A4B478B04F7" modified="2019-11-13" version="1">MTEERVILVNEQDEQIGTMPKMEAHEKAMLHRAFSVFVFNERKELMIQQRAKHKYHSPLLWTNTCCSHQRVGERNVEAGKRRLMEEMGFVTDLTESISFIYKAPFDNGLTEHEFDHIMIGTFNDEPKINPDEVEAWKWMDLESLKTDMKTNPKQYTAWFKIIFDKFYDHINITES</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF40</accession>
    <name>A0A5C6ZF40_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA topoisomerase (ATP-hydrolyzing)</fullName>
            <ecNumber evidence="3">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_11865</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003918">
        <property type="term" value="F:DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.670">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001241">
        <property type="entry name" value="Topo_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013759">
        <property type="entry name" value="Topo_IIA_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013506">
        <property type="entry name" value="Topo_IIA_bsu_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018522">
        <property type="entry name" value="TopoIIA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00204">
        <property type="entry name" value="DNA_gyraseB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00433">
        <property type="entry name" value="TOP2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56719">
        <property type="entry name" value="SSF56719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00177">
        <property type="entry name" value="TOPOISOMERASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Toprim" evidence="5">
        <location>
            <begin position="408"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD88656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="617" mass="70816" checksum="D2857D329E31E1A2" modified="2019-11-13" version="1">MTQETKYTEDNIRSLDWKEHIRMRPGMYIGKLGDGSSPDDGIYILMKEVLDNSIDEYVMGAGKTIEISIQGNKVIVRDYGRGIPLGKVVDVVSKMNTGGKYDSRAFKKSVGLNGVGTKAVNALSSYFRVESTRDAKSASAEFEQGELINHELLDDTSRRKGTKVSFIPDEVIFKNYKYRNEYIEKMLKNYVYLNPGLTILFNGEKYYSENGLKDLLSENITESDRLYPIIHLKGEDIEVAITHSKTQYSEEYHSFVNGQNTTQGGTHLAAYREAIVRTIREFYGKNYEASDVRKSIVTAISIKVMEPVFESQTKTKLGSTDMGGEFPTVRTYINDFLKKYLDNFLHKNPDVAEKMQRKILQAERERKELSGIRKLAKDRAKKANLHNKKLRDCRVHFGDTKNERYLETTLFITEGDSASGSITKSRDVNTQAVFSLKGKPLNCYGLSKKIVYENEEFNLLQAALNIEESTEDLRYNNVVIATDADVDGMHIRLLLITFFLQFFPEVIKEGHLYILQTPLFRVRNKKKTIYCYSEEERRNAMEELKPKPEITRFKGLGEISPDEFVHFIGEDIRLDPVMLDKDMSIEDLLSFYMGKNTPTRQEFIIDNLKVELDVIEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF58</accession>
    <name>A0A5C6ZF58_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Multidrug effflux MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_17045</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Bcr/CmlA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000025">
        <property type="protein sequence ID" value="TXD87378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990961">
        <property type="term" value="P:xenobiotic detoxification by transmembrane export across the plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004812">
        <property type="entry name" value="Efflux_drug-R_Bcr/CmlA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00710">
        <property type="entry name" value="efflux_Bcr_CflA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="50"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="216"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="250"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="281"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="308"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="341"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="372"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="8">
        <location>
            <begin position="9"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD87378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="406" mass="45095" checksum="09DEB400A2BC856D" modified="2019-11-13" version="1">MKKTPVFKLEFVVLMASLMSIVALSIDALLPALPEIGDSLNVTDPQDNQLLITMIFLGLGFGQLIFGPLSDSFGRKPMVYFGFSLFVIASIVCVTTQNFETMIIARVFQGIGLSSPRTISIAMTRDTYSGDYMAKILSIITMFFILIPIVAPTYGQFVMQLFNWQAIFNVNLIIGLIVIIWFFKRQPETLPKERRIAFKPSIFITGAKEFIRYKEAVAFTIISGFITGSFMVYLSTAQQIFQEQYHLGELFPYIFASTAFAVGFATFANSRLVMRFGAFHIVLLATVAFAINSIVYVLLFYSGNNPSIQVLIVFFLIQFFAVGFLFGNLRSLAMEPLGHIAGIGAAINGFASTVMAVPIATFIGGFVNDSVLPLFIGFSIFGVLSFATMYYLKLQRRVLHVANVRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFJ2</accession>
    <name>A0A5C6ZFJ2_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Uridine phosphorylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">deoD</name>
        <name evidence="6" type="ORF">ESY86_11230</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PNP/UDP phosphorylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004731">
        <property type="term" value="F:purine-nucleoside phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009164">
        <property type="term" value="P:nucleoside catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd09006">
        <property type="entry name" value="PNP_EcPNPI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01627">
        <property type="entry name" value="Pur_nucleosid_phosp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004402">
        <property type="entry name" value="DeoD-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018016">
        <property type="entry name" value="Nucleoside_phosphorylase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43691:SF2">
        <property type="entry name" value="PTHR43691:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="SSF53167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00107">
        <property type="entry name" value="deoD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01232">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PNP_UDP_1" evidence="5">
        <location>
            <begin position="16"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD88804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="233" mass="25599" checksum="1B92DF7B8410CAD6" modified="2019-11-13" version="1">MSVHIEAKKGEIAETVLLPGDPLRAKWIAETFFENPILYNDVRGMLGYTGTYKGKAVSVQGTGMGIPSALIYCHELINNFGAKNLIRVGSAGSYNKEVNIRDIVIAMAASSTSGINNSRFFNADYAPTANFELFMKAASYAKSKQIEIKAGNVLSSDEFYEDDVNTYKKWAKFGVLCVEMETAGLYTIAARHQVKALSILTISDSLVTKETTTTEERESTFETMIEIALSTLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFQ0</accession>
    <name>A0A5C6ZFQ0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Acyl-CoA thioesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_10550</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the acyl coenzyme A hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016790">
        <property type="term" value="F:thiolester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040170">
        <property type="entry name" value="Cytosol_ACT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033120">
        <property type="entry name" value="HOTDOG_ACOT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11049">
        <property type="entry name" value="PTHR11049"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51770">
        <property type="entry name" value="HOTDOG_ACOT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HotDog ACOT-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD88927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="127" mass="14609" checksum="780E006487B85549" modified="2019-11-13" version="1">MRFHTRKWVKPEDLNPNQTLFGGQLLAWIDEEAALYTIIQLENPKVVTKYMSEINFMSSAKQGDIIEIGIEVLKFGISSMTLKSEVRNKMTRETIITVDKIIMVNLGEDNKPKPHGKTEVEFVKDRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFV8</accession>
    <name>A0A5C6ZFV8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_15645</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="59" mass="6732" checksum="1BF52ACC87F0F41D" modified="2019-11-13" version="1">MKTNLAFILILIPLVCISQIESLESNTKIADSLETLGQYKEAIPYRDLALQEQHHSKDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFZ6</accession>
    <name>A0A5C6ZFZ6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">M3 family metallopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_12475</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase M3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06456">
        <property type="entry name" value="M3A_DCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034005">
        <property type="entry name" value="M3A_DCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024077">
        <property type="entry name" value="Neurolysin/TOP_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024080">
        <property type="entry name" value="Neurolysin/TOP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045090">
        <property type="entry name" value="Pept_M3A_M3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001567">
        <property type="entry name" value="Pept_M3A_M3B_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43660">
        <property type="entry name" value="PTHR43660"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01432">
        <property type="entry name" value="Peptidase_M3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase_M3" evidence="8">
        <location>
            <begin position="225"/>
            <end position="673"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD88548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="677" mass="77294" checksum="CC5A57D36EE28DD4" modified="2019-11-13" version="1">MNILNHTYDTPYHTAPFSKIKNSDFLPAITQGIIDAKADIDAITSNPETPNFENTIEALDFSGESLDRMSSIFFNLNSAETSEELQSIAQEVSPLLSEFSNDITLNEALFERVKAVYQKRDDFTLSVEQNTLLDKTYKSFSRNGANLSEDKKNELREIDKKLSQLSLKFGENVLAETNAFQMHLTNENDLNGLPEGAKEAAKDLAESKDLEGWLITLDYPSYIPFMTYANNRELRKKLAIASGAKAFHEDKLDNQDKVLQIAKLRFERAQLLGYKTHAHFVLEERMAKTPENVAQFLNELLEKAKPAAEGEFHKLEAFAKDLDGIEQLQKWDSAYYSEKLKQKLFDLDDEQLKPYFKLENVIDGAFTIAERLYDLKFEQIDTIDKYHKDVLTYKVTDTNGNLISIFYADFFPREGKRNGAWMTVYKSQYIKNGVNDRPHISIVCNFTKPTKSKPSLLTFNEVTTLFHEFGHALHGMLANTTYPSLSGTSVFWDFVELPSQVLENWCYQKEALELFATHYETGETIPMALIEKIKASSTFHEGMQTLRQLSFGLLDMSWHGIDPSSIKDVKTHELEAFEGTKLYPDVAENCMSTSFSHIFQGGYSSGYYSYKWAEVLDADAFEYFLEQGVFSKDVAKRFKDNVLSQGGTEDPMTLYKRFRGKEPQPDALLKRAGLMEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG27</accession>
    <name>A0A5C6ZG27_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_13770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023021615" evidence="1">
        <location>
            <begin position="19"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="69" mass="7864" checksum="B669C595B6B4528E" modified="2019-11-13" version="1">MRNLVIILFFLAANLGSASVEKNETRKNYDNYEDATIHFLDGASVRGYGKIISTFKSIKSSLRYAWMAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG37</accession>
    <name>A0A5C6ZG37_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">T9SS type A sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_09710</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023087019" evidence="1">
        <location>
            <begin position="20"/>
            <end position="1270"/>
        </location>
    </feature>
    <feature type="domain" description="Por_Secre_tail" evidence="2">
        <location>
            <begin position="1212"/>
            <end position="1269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1270" mass="132367" checksum="C7F25D938A1B232E" modified="2019-11-13" version="1">MKKLYILLTALILGSVSYGQDVLTEINVNSSSSNNPSTTGNIANVSSIGLTRGTGASYDSGDDYAVAGLNAPDNASAITNDDYIQFSISANATYELELSQLEIKLGRRDTEGPTRFRIYSSTDGFATAGTALLNSNPSELNADGSTTFQTKGRKIFSYDLNLNSGVEGTVTFRMYAWGGSPSDPNNALIKVFASASSPNNEPANSGNVVWTDYVSGDAGVRITGSVTSAESNIVATAFDPTDNIDYTAYSASSGLTNANAIKIAEFSIQDGGDDLSDADLVGTTLTSLGFNIPNFNNLAALAIFDGSTNVSEVSSVTASTNFSAINSGAGITATDNAAKTFSVYATFKNTVTDNQQIQLTIESAAALASGSNFASPNAGAAATPVVGDDNRIEVIATNLIFNTNPPNFVVNAVVVPAPSVNAIDPNANTDLDFTGAVALTPSTAGIFDPGATTTVSAVSGLATFSNIGFDTIGTGYTLQASSGSLTVATSTSFNISAAPGDGFIINAINDENIINFDTTVPGVNNGTFTGTGIVKTPANGQLDSDAWQTSGMSDGPTGFALNFTTGDYARGTSTGAVTTGGFYSFEVAPSNYALGVQATDDDFTPGTVVLKTKNNTGSTVTKFIVQYKVYVYNDQNNSNSLNFAYSNNNTSYTGVTGLNFTSPSTASTTPSWEFVTRTAVIDGINIPNGSFFYLRWRGNDVSGTGARDEFAIDDIQLNFQPVTLTTYTYDNSIWTPDDPSGSINPSNIIIVQNGNANISADTNADSVNIAAGASLTVNSNATLNATQTTLESSSTLFSSLILEQDGADIGAILGGISYERYTNVVGSGAVGTGGNDLLSLPLMSPGQTFADFITFGDPQSNASVLPDNGIFYAFGPYNNAAQTYVNFGMTAATPLERGKGYRAASKDVSNNRLTFSGTIETGSVSRTINTPIGGNQWNLIGNPYPSYVTSTGANSFLNAANIAALDPSAAAIYGYNNNNGPSIGTIGNFTIINGASNASVNIAPGQGFFVANNTAAGTNSITFDYDMATTTGTDDFILGRDATESYNLRLKASSGATDFATEIYFNSNSGLGLDPGYDAALMSAFASNFMIYSHLVENNEGRNMAIQSLGTAAVNEVIIPLGLKASQGQQVTIGMELSSLPADVQVYLEDNLNNTFTLLNTGDYTFTADSAIDGTGRFFLRTSNSTLSTTAVDVAGLQMYTNNDTLFVKGLLNANTAVNLYDLQGRLVLNTQLDKGSNSNQVDVSNMTTGVYIVTLSNATQQKTQKVIIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG66</accession>
    <name>A0A5C6ZG66_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_13255</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="73" mass="8100" checksum="192FD52475040C0F" modified="2019-11-13" version="1">MGNQGLTLIHSGGTAINCLKHISDHSEVLLDQFNPTSSLEKSKKMRYGMAYNPNLTDIYNLSKIASEEFPECP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG70</accession>
    <name>A0A5C6ZG70_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023135186" evidence="1">
        <location>
            <begin position="21"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="136" mass="16336" checksum="9E8A1E7FD56BDFDB" modified="2019-11-13" version="1">MSRILLVLCLTLALQTTVFSQTNNEARQKEKYEEKVEENKQKYIQDFLKSLDVDAFQKEIIYQSIDTYFDEVTKIQTFGLKSYEMKDEIDKMRRRHFADVRTIVSEEVMQRIEDAVTGKWDPKKDKKKQKKSRRDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG73</accession>
    <name>A0A5C6ZG73_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA (guanine-N(7)-)-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">tRNA (guanine(46)-N(7))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">tRNA(m7G46)-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1 2" type="primary">trmB</name>
        <name evidence="2" type="ORF">ESY86_14010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>guanosine(46) in tRNA + S-adenosyl-L-methionine = N(7)-methylguanosine(46) in tRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42708"/>
            <dbReference type="Rhea" id="RHEA-COMP:10188"/>
            <dbReference type="Rhea" id="RHEA-COMP:10189"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74480"/>
            <dbReference type="EC" id="2.1.1.33"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">tRNA modification; N(7)-methylguanine-tRNA biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class I-like SAM-binding methyltransferase superfamily. TrmB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.33" evidence="1"/>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00989"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008176">
        <property type="term" value="F:tRNA (guanine-N7-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01057">
        <property type="entry name" value="tRNA_methyltr_TrmB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003358">
        <property type="entry name" value="tRNA_(Gua-N-7)_MeTrfase_Trmb"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23417">
        <property type="entry name" value="PTHR23417"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02390">
        <property type="entry name" value="Methyltransf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00091">
        <property type="entry name" value="TIGR00091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51625">
        <property type="entry name" value="SAM_MT_TRMB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="1">
        <location>
            <begin position="203"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="224" mass="25930" checksum="2E33F4F8E4B2DF30" modified="2019-11-13" version="1">MGSKNKLKRFRENETFDNVFQPKREDLVDAAYELQGQWNAKVFKNDHPLVLELGCGKGEYTTALAKKFPNKNFIGIDIKGARFWRGAKSALEEGLPNVAFLRTQIELVDEAFGKSEVDEIWITFPDPQIKYKRTKHRMTNSIFLERYKKILKPEGVVNLKTDSEFMHGYTLGLLHGGGHEVLYANHNVYKQEGSPDEVTSIQTYYESLYLNQDKPITYIRFKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG86</accession>
    <name>A0A5C6ZG86_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PorT family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_10025</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025665">
        <property type="entry name" value="OMP_b-brl_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13568">
        <property type="entry name" value="OMP_b-brl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022733441" evidence="1">
        <location>
            <begin position="20"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="OMP_b-brl_2" evidence="2">
        <location>
            <begin position="26"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="237" mass="27392" checksum="6090DE0995D545FE" modified="2019-11-13" version="1">MKNIFLLIFLCMAGQTASAQLFSKEKIRNLENFDKQILSWGFFLGLNQYDYQFNYEEDLPDILVETTTGFSVGLISDLRISEHLNLRFEPGLFITQRNLQYDPNYFIGQTFTDADLLREVKSTYVHFPLLLKVSTKRINNFKPFLLGGISTSLNLSSNEKNPDDNSAGEFRTKKNVLFYELGFGVDFYNQWFKFTPSIRGIFAINDELVPDKDPNSPWTGNVTTMKTRGVFINFTFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGA8</accession>
    <name>A0A5C6ZGA8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_14725</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="350"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="3">
        <location>
            <begin position="94"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="5">
        <location>
            <begin position="405"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="6">
        <location>
            <begin position="646"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="696"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD87922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="766" mass="88230" checksum="D9A2EF26490A8584" modified="2019-11-13" version="1">MRFNNKFVCLPQINCIALTMNYPKPTFIAVLLLFFGFQNLFSQELLVFDKQSKCSFNNERVETLIQNDSLYKATILLNEALAFTKKYGFTKYEAQAYNGLGMVFSEMGNNNSAKMYYYKALSIYDSIHEPHGRDYVLSNLANTYLLYKKYKQFDSIYPIAQSSAKKLNSELFFINLENEIKRNYYTNRNDALIKLAEYSFNQLARTDFDKLSYSRDYKSETLEKRLKYNSLYYKAIGLIKLGHFDEGYTLLFSIDIKDFKKSIVLNNDANRQLSTLNYYKFRYFHEFKKQKDSAVAYLLKSDEYKYSAMLEYERATSQNGELIYKILKTEEQLSSANKLRINDAKLSRSFIASTIISSILLVVVVIFFFYYYKTRKNIETINEELKNSNKKLIKRDKDRSEFFSVLSHELRTPIYGISGLSTLIEQEQSEVKKEAYLKSLISSSNYISILIDNILQATRAKFEDKQLRLKPGRIDPILQNVINTVKVAAENKGLNLFSNIAHSDEDEYIMIDKVAFSQIMINLAYNAIRYTNKGFISIDVSEVNRTDAQIELLFEVKDSGIGISEEHRQTVFSAFENKMFLQKNSSGSGLGLYIVKTLLKSHGTEIDFVSKPNKGSSFFFNVTFDLCEKPETVAHHEDLEARIDNHVLIVDDNKINLLITKKTLERIPGCTCETASNGKEAISLVKQKDFDMVLMDINMPEMDGFEVTKHIRLFNPNIPVLALTALNSGEVSAKAEACGMNQVITKPYNFDDFKAIVRGYSKVYQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-02-10" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGE7</accession>
    <name>A0A5C6ZGE7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Sigma-70 family RNA polymerase sigma factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_15630</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="247" mass="29489" checksum="5D195AA5CCE96CB3" modified="2019-11-13" version="1">MSEKFPVLDFGNYHFGKMLLYLLVWELGKGQHQLRYFFHLLDIYCNLYKTHVDLLQIFQPMDRDLLEDLKIALRKNDTSLLGRIYEKHRLPFVKFASRYEVSNDEVIDIYQDAILALRDNVVNGTVKKLDCTIKTYLFSIGKFMLFKRYKDLNLLNALTEETIMEVAYDFPYEDSALQDELQEKIDEHFEQLGDKCQKVLKLFYYDGFTLEEIQKQLNYDNYNVVKSQKSRCLKTLKELISKHQNDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGH2</accession>
    <name>A0A5C6ZGH2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">M20 family metallopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_13455</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023023629" evidence="1">
        <location>
            <begin position="25"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="M20_dimer" evidence="2">
        <location>
            <begin position="216"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="441" mass="47557" checksum="AE70AD3F04855660" modified="2019-11-13" version="1">MILNTQLKQISLFASLAFCTLSMAQQDKMEKKILKSVDKHLEASIALLKKTVNINSGTMNFEGVRAVGTLYKEELDQLGFETQLTSGEAYDRAGHLIAKTTGKKGPKFLMIGHLDTVFELDSPFQEFIMLDDSMMKGPGVADMKGGDVIIILAMKALKDAGVLEDMSVEIIMTGDEEKSGSPLELSKKDLIDAAKRADIALGFENGDNNPKTIVVSRRGSSDWQLTVTGQPAHSSQVFSKEVGVGAIYETSRILNEFYLQLANEKDLTFNPGFILGGTDITINDDLTGGTAFGKNNVVAEKTVVHGDIRAVSPEQLKKAQDVMTKIVQAHYPKTTAELIFNDEGYPPLALTEGNTKLLGIYDGVSQDLGFGPVEAVNPRNAGAADISFTSGHVEMALDGLGLTGGSGDHTIEETGDLNTIATQAKITAVLMYRLMKKELGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGM6</accession>
    <name>A0A5C6ZGM6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">4-phosphopantetheinyl transferase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_13105</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008897">
        <property type="term" value="F:holo-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008278">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01648">
        <property type="entry name" value="ACPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="SSF56214"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACPS" evidence="2">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="191" mass="21855" checksum="0FE2E2007D451A92" modified="2019-11-13" version="1">MIGNDVVDLAQAAKDSNWRRPRFLDRIFTAQEQESISNSNNKDQTVWLLWSLKEAAYKAYVQETGHKFFNPKKLRCQMMSSTEGIVEISKRRYRTTSKLTEDFIHSIASTEAHEQNLNACFPLSKTDHGFQSEAVRSVLIETLSKDNSFRSTNLQVRTDDLGIPSLYSENRKLSKRLSFSHHGAYGAFVIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGW5</accession>
    <name>A0A5C6ZGW5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mannose-1-phosphate guanylyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12555</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="1">
        <location>
            <begin position="7"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="359" mass="40946" checksum="979DC1BA46D50BBF" modified="2019-11-13" version="1">MNTNYYAILMAGGVGSRFWPVSTEAFPKQFHDMLGTGDTLIQKTFKRLSKLIPKENIFILTNERYNDLVFEQLPEVTKRQVVLEPAMRNTAPCILYAALKIQKENADAVMIVAPSDHWIEDENAFAQNVQKAFDFCSKHDALMTLGIQPTFPNTGYGYIEYDKTSEEEIKPVSQFREKPDYDTAKSFIAQGNFLWNAGIFMWSVKSVVEAFRNNQAELYQLFETGINDYNTDREHDFISQNYAKAENISVDYAIMESSKNVYVLPATFDWNDLGTWGSLYDKLDKDEADNAVVNAKTLTQDASGNMIRSKANKIVVVDGLKDYIIVDKEEVLLIFPKTKEQDIKKVLQKVKDKFGSQFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGX0</accession>
    <name>A0A5C6ZGX0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PKD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_14610</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00041">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000859">
        <property type="entry name" value="CUB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022409">
        <property type="entry name" value="PKD/Chitinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000601">
        <property type="entry name" value="PKD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035986">
        <property type="entry name" value="PKD_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035914">
        <property type="entry name" value="Sperma_CUB_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00431">
        <property type="entry name" value="CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00089">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49299">
        <property type="entry name" value="SSF49299"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49854">
        <property type="entry name" value="SSF49854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50093">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023041323" evidence="1">
        <location>
            <begin position="19"/>
            <end position="1265"/>
        </location>
    </feature>
    <feature type="domain" description="PKD" evidence="2">
        <location>
            <begin position="153"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1265" mass="133384" checksum="2CE0ADBA18B63F8F" modified="2019-11-13" version="1" fragment="single">MKYLYYVILFLFSLNALAQDLVMQNGAFTRCAPDKFYDSGGASGFYGDNENFIITICPSDDDAFIILDFTAFSTQLNTDVLTIYDGDDVTAPLVGSYSGAAGPGKVIASETNTSGCLTVQFVSNGSGTTTGWAADIICAVPCQDIDPFVESTIPEANATGVVQIAANDSVTFTGNANFATDGTGATYKWNFGFGPAITGQTVTRTFANAGQYNVILTVTDNNPLGCSETTTIQVFVVGANIVVNTSAFTIEQLVQDVLIDSPCAAVSNITSSTGTNFSSVNGIGYFVSDGSMFPFTDGVLLTSGDATAVRGPNNNALSAGGSSWPGDAQLASIVGIVSNNASIIEFDFVPLADSISFDFLMASEEYNGGSFECDFSDAFAFLLTDSNGTTTNLAVLPGTTTPILVTNIHEANSNCAAINEQYFGGYTPSNQPPMSFDGRTEVFTAQSAVTPGETYHIKLVISDARDTAYDSGVFLKAGSFNLGGNLGEDITIAAGTAGCGGADVLLDTNVPTAAHIWFRDGVEIAGETNSTLTVTEPGTYAVDVYFSEDCQFSSSILVEFKPSPVANTPEDLSICINETAGEFDLTDNDENILGDQNPDDYITSYHLTEQDAIDNVAELTSPYTNVSNPQVIYARIADTSQECFDTTPFEIGYTSLEINNAVTPFEVCDDNADGFAMFTLTDKDVEVIGDLEPTTASVAYHVSQADADSGTNALTSPYVNVDANNQTIFVSVASVGDPGCFNTSSLELVVNPLPIATTPAPLKVCDDDFDGFASFDLTLKTAEIVGGQTNLTLTYHESQEDANTGDNPKASPYTNINPSVQTMYARLETDATGCFAIAELTLIVEEIPEIAQISDYELCDDNTSGDETETFDLSSKTDEVINGQANLSVNYYLSLEDAETGNNPLPNDYSNIATPQTIFYSLTNTSTFCTNTGSLDLVVKPLPIIFDPTPLEVCDDGVPDGITSIDLSMKNSEVTGNNPGYTVSYHKDQADADSDTDALPIPYTNEANGQVVLVRVEDNTTSCHATTSLVLTVQQAPVANDPAPLEYCDPDSDGFGVFDLTMGDAEITGGVAGLEVSYHETFADAQNGVNAVGSPYSNIVAGTQVLHARVESATVATGCATLVELVLIVNPTPAVPAAISDYVLCDSDADGFAQFDLNTKETEITESQPPLAADLDLILTYHLSAADALSGNDPIPNVGNYTNTGNPQTIFVRLEGESNGCAGTGSFEIRVDLPPVAVLPAPLQLCDDGVADGVTVFDLSVRDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGZ0</accession>
    <name>A0A5C6ZGZ0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_08480</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023094032" evidence="2">
        <location>
            <begin position="20"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="166" mass="18614" checksum="E1B184602C28A129" modified="2019-11-13" version="1">MKKLIAILMLCFMALSINAQTVISNGKSYTVKKSKIFLDGKEVSTTLSEADKIDILGRASTISEKIDADVKAKREAKALEKANKKAEKALKKAEKAQKQAEKTLKQNQKAQDKLIKASRKLKNAESKYQKLKRKGKLAPNDDAKWLKKIEGIKKDITKAQQQLERS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH03</accession>
    <name>A0A5C6ZH03_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycogen synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_13730</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013534">
        <property type="entry name" value="Starch_synth_cat_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08323">
        <property type="entry name" value="Glyco_transf_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_transf_5" evidence="3">
        <location>
            <begin position="5"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="270" mass="31455" checksum="ED7F9C4EC1D10FE4" modified="2019-11-13" version="1">MKDKRILYVSSEVVPYLPETEISSMSFEAPKMVNKQGGQIRIFMPRYGNINERRHQLHEVIRLSGINLVINDLDMPLIIKVASIPKERIQVYFIDNEEYFKRKATLTDENGQLFKDNDERAIFFAKGVIETVKKLNWAPDIIHVNGWLASLLPLYLKEFYKTEPLFTESKIVTSVYNQSFEGTLDKNMIKKIRFDNLDENSIKALENPTYNNLMKVAIDNSDAIIRGSQELPEELEAHLKSIEQPVLDYYPIEDFSDQYSEFYNTKVLNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH45</accession>
    <name>A0A5C6ZH45_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF1853 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_10945</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015003">
        <property type="entry name" value="DUF1853"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08907">
        <property type="entry name" value="DUF1853"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="268" mass="31748" checksum="8901F721B61B76CA" modified="2019-11-13" version="1">MNNQALLQARYSGFCNTALLWQGDAIRQLQQLDIHDYQATFLRKLERPLRLGQLAERFVFNQLDALKDFEILAENLQIQDQKRTVGELDALLLKGSQPIHLEMVYKFYLYDATLGLTETQKWIGPNRRDSLEEKLDKLQKQQLPLLHSEFCRPILEKLNLKPTQFQQKVLFKAQLFVPYQNESGFDSLNPGCVKGFYLYPNQLREFTDSKFHIPPKMDWFLEPDTFVDWQTFESFKKNSNSFLEQQKSPMFWIKKPNGELLKAFLVWW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH72</accession>
    <name>A0A5C6ZH72_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cold shock domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_11680</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04458">
        <property type="entry name" value="CSP_CDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011129">
        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002059">
        <property type="entry name" value="CSP_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00313">
        <property type="entry name" value="CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00050">
        <property type="entry name" value="COLDSHOCK"/>
    </dbReference>
    <dbReference type="SMART" id="SM00357">
        <property type="entry name" value="CSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51857">
        <property type="entry name" value="CSD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CSD" evidence="2">
        <location>
            <begin position="91"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="153" mass="17753" checksum="74EE9033B71FE55A" modified="2019-11-13" version="1">MAKSQQTFNKSEKEKKRLKKRDEKRKKMEARKIEKEQNDGSDNIPFAYVDQFGNLTDTPPDPADKIKVKAKNIVIGVPKQEDMDEEEFDPIRKGKVSFYDNSKGFGFIIDIEDQEKYFCHVSNLIDPIEENDKVEFELEKGPRGLNAVRVKVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH77</accession>
    <name>A0A5C6ZH77_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_08940</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="171"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="204"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="237"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="10"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="414" mass="48444" checksum="4C5189D4EC86E014" modified="2019-11-13" version="1">MFTVASIYGLHNGADLFEKQKNEIERLNQETEAEIKNTLSYYDTGKKGPDEQPWVDNNEPFWAIYNAPTYQFKTPSPTIVYAIGQTEQYGFYKRITTWSNPYDADMTQEISNPERIQSGNLDFSFAVLFLLPLLLLVLLYNIKGLEAERGFLPLVIVQAGSKNWWILSRTAFYAILLLLVLFGLMLYGATLTDVFETKNDFWKIFLWVTISLFFWLVIYFLILYYGNNTVSNTLQMIGVWLLLAIIIPATIQQWIAIEKPTNLMVDLIDVKREKTSEIYEQSKELIDAQLFELYPDLKETKTFRDTTIVKNDRGYSTDALVNIEMKNATKGIEADNYAKNKLVETTYWFNPVTYFQNKLNKLTSTHYEDYESYRNEIQKSVDNRLETMVFDIWNNVEVDKLRYLEYNAIFTNDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH99</accession>
    <name>A0A5C6ZH99_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="25"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="131" mass="14692" checksum="412258615684F9F7" modified="2019-11-13" version="1">MINTEEFVIRLQKVIDHYGESASSFAEKIGVQRSSISHILSGRNKPSLDFVLKVLASFPDVELYWLLNGKGHFPSEEKHPEVATVSKVRTTTENETGAKTAVKTNLGIQDKSIERIVIFYTDGSFKNFEDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHC7</accession>
    <name>A0A5C6ZHC7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase family 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_10125</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="238"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="264"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="9"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="315" mass="35707" checksum="03CA2CFB50A4F25D" modified="2019-11-13" version="1">MKPTKDIAVVIPVFNEADNLDELYKRLVVSVSKISENYELLFVNDGSSDASIQKLQAFSEADARVFYIDLSRNFGHQVAVSAGLDACQSKVAIIIDSDLQDPPELIPKLYAEYQKGFNVVYAKRETREGETYLKKLTSKLFYRLLQRLTNFDIPLDVGDFRLLDAKIVRELRKMPEHNKFLRGQIAWLGFKQTHVTFKREARKHGTSGYSYSKMFSLAFDAVTGFSDKPLLLVTRMGFVISLVSFVVILFAMFSHFILKETITGWTSLIISSLFIGGIQLLSIGIIGEYISRISTNVKNRPMYVVQETNLDRGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHF6</accession>
    <name>A0A5C6ZHF6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Quinol:cytochrome C oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_14375</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="205"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="246"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="280"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="323"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="363"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="388"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="420"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="466" mass="52827" checksum="7061DB75F526944A" modified="2019-11-13" version="1">MYTISGKLRTVAFVLMILGLIGVVYGFMTSHKSLDDVKEMLAAEHAGHGEDAVDTKAHVVAGVEDHSDNAHEANAIGALEDPASANIEHVGTDAHVNDEHAEHVQHLIANRPWSAIYVAALFFFTIALGALAFYAIQYAAQAGWSPLLLRVMEGITAYMLPGGLIVLAIAILSGTIGHYNIFIWMDPEVVKEDLLIRNKSSYLNIGWFAIRGLIFLTGWFLYRHFARKFSIAQDEANDNKNFKKTFRISAGFLVFFLYTESIVSWDWIMSVDPHWFSTLFGWYVLAGMMVSAITVIAMVTIYLKSIGHLPLVNDSHLHDLAKFMFGFSIFWAYLWFSQFMLIWYSNIPEEVTYFVTRFEDYQFLFLGMVVLNFVFPLLILMNSDFKRLPWFIMMAGIVILVGHYIDVFNMIMPATVGDQWYIGIPEISSMLLLGGVFLLVVFTALTKAPLMAKRNPFIKESEHFHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHM0</accession>
    <name>A0A5C6ZHM0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Polymer-forming cytoskeletal protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007607">
        <property type="entry name" value="BacA/B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35024">
        <property type="entry name" value="PTHR35024"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04519">
        <property type="entry name" value="Bactofilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="122"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="145" mass="15293" checksum="895C8EC25CDD2E27" modified="2019-11-13" version="1">MFSEKKSTKMAENSNSQQNTIAKGTQITGDIVSEGDFRIEGKIEGNIQTPGKVVIGKTGVVNGTLKAANADIEGYFSGKLFLTDTLSLKATAHVEGEVEVGKIAVEPGANFNATCQMKGALKESNSATNNNQKGKEKTVEKGQVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHM1</accession>
    <name>A0A5C6ZHM1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_13765</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="152" mass="17413" checksum="4F1BC22D261F7FDC" modified="2019-11-13" version="1">MTRKILYAILIGTVLFSCGIKKMSNDEIAQTTEILVAKNKANKTLKKETTEGALTDKDGYNDIGKFKYSVYYDETSKALYRIENIEMTDVTLTETYYFKDNDLYFIETLESSAAEKAIYTKGFELLMKKNASDAETKLLINKAKRFKTAFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHQ3</accession>
    <name>A0A5C6ZHQ3_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Sulfate adenylyltransferase</fullName>
            <ecNumber evidence="1">2.7.7.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_07940</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.4" evidence="1"/>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004781">
        <property type="term" value="F:sulfate adenylyltransferase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006790">
        <property type="term" value="P:sulfur compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04166">
        <property type="entry name" value="CysN_ATPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03695">
        <property type="entry name" value="CysN_NodQ_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04095">
        <property type="entry name" value="CysN_NoDQ_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041757">
        <property type="entry name" value="CysN_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044138">
        <property type="entry name" value="CysN_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044139">
        <property type="entry name" value="CysN_NoDQ_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011779">
        <property type="entry name" value="SO4_adenylTrfase_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="SSF50465"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02034">
        <property type="entry name" value="CysN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Tr-type G" evidence="7">
        <location>
            <begin position="5"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD89702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="417" mass="46912" checksum="C2176AE53B6A2D1B" modified="2019-11-13" version="1">MMDNNQLLRFTTAGSVDDGKSTLIGRLLYDSKSIFEDQLQAIETTSKKKGHDGVDLALFTDGLRDEREQGITIDVAYRYFTTPKRKFIIADTPGHIQYTRNMVTGASTANAAIILVDARHGVIEQTKRHSFIASLLQIPHLIVCVNKMDLVDHKEDAYNKVIEQFEDFSSKLLVRDVRFIPISALNGDNVVNRSKNMEWYQGAPLLHTLETMHISSDINKVDARFPVQIVIRPQNEAHRDYRGYAGRVASGVFRTGDEVTVMPSGFTSKIKSIDTMDKVLDEAHAPMSVSITLEDDIDVSRGDMIVRSNNKPEPLQDIEVMLCWLNNEPSKPRAKYSIHHTSNVQTAMIKEVIYKINIETLDRVNDDKTLTMNDISKVKIRTTKPLIVDSYRENRTTGSVILVDDATNETVAAGMIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI30</accession>
    <name>A0A5C6ZI30_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2238 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08175</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014509">
        <property type="entry name" value="UCP020606"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09997">
        <property type="entry name" value="DUF2238"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF020606">
        <property type="entry name" value="UCP020606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="164"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="202" mass="23008" checksum="6C9DD6B4FA8DDCF9" modified="2019-11-13" version="1">MKLIYTLLGLSLLLLIWSAINPYDYFTWFLEVLPAVLGVLLLLFTFNRFRFTNLVYTLVFFHAVILIIGGHYTYAEVPLFDWIQQYFGQSRNNYDKLGHFAQGFVPAMIARELLLRKAVVLKTSWLKFIVVCIAMAISVAYEFVEWAVSLGTGEGGDSFLGTQGYIWDTQSDMLFATIGAIMALLIFSPRHSHQIKNITTEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI61</accession>
    <name>A0A5C6ZI61_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_08840</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="60" mass="7020" checksum="7A519DF08C405A6F" modified="2019-11-13" version="1">MKAEDPVPKVGATSTKIDLILRQEKILIEVKMIKESDNDESKFIKQLKEDIQSYHVCQWM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZII9</accession>
    <name>A0A5C6ZII9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_11010</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023100957" evidence="5">
        <location>
            <begin position="23"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="7">
        <location>
            <begin position="142"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="6">
        <location>
            <begin position="289"/>
            <end position="766"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD88763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="792" mass="89755" checksum="8F68D5E3ECEAE0CE" modified="2019-11-13" version="1">MTTKSFIVIIFVLIVSTVFAQAQDKFTLSGIITDASTNETLIGVNIIFPDEQTGTNTNEYGFYSITLPKGEYTLSVSYLGYKPVQEIIVLDADKNMNYKLNASSESLDEIVITRDVERLNIRKPQMSMNALSINTIKQMPVVLGEVDVIKSITLLPGVTNAGEGASGFNVRGGAVDQNLILLDEATIFNSSHLFGFFSVFNPDAIKDIKLYKGGIPAKYGGRVSSVLDIYQKDGNSNKFQMNGGIGIVSSRLLVEGPIKKEVGSFLLAGRSSYAHLFLPLFDLDSKAYFYDLNTKLSYRLDDKNSIFLSGYFGRDVFNISDSFENTYGNTVVNFRWNHLFSDKLFSNFSAIYSDYFYGLNLNFVEFNWDSGISNFNLKYDLKNYISTDFKLEYGINSIYYKFNPGDIKPSTATSGINPFKLTDKYAFENAIYIDAEHQVTNKLALSYGLRLSTFLRLGQDQLNQYENDNPIEFNEQLQIYEKAVPIGSSSFRRSEVLKSFMNFEPRLSLAYQLNDYSSVKGSYNRMSQYLHLLSNTNSPTPLDIWTPSGTFVKPQILDQVAIGYFRSFNNNAYSLEVESFYKKIKNRIDYVDGADLIANNAIEQIILNGRSRAYGLEVLFRKNEGRFTGWLSYTLSKSEQQTEGRTPEEIGINNGDWYYTPYDKTHDISLTGNYELNKRWNFSSNFIFTTGQPSTFPNGQYEYNGIIVPNFEARNSSRLPAYNRLDLAATYNPKPNSAKRWKGEWVFSIYNVYNRRNAASITFGQNRSTGVNEATRLAIFGIIPSVSYNFKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIM3</accession>
    <name>A0A5C6ZIM3_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">1-acyl-sn-glycerol-3-phosphate acyltransferase</fullName>
            <ecNumber evidence="2">2.3.1.51</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_07645</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a 1-acyl-sn-glycero-3-phosphate + an acyl-CoA = a 1,2-diacyl-sn-glycero-3-phosphate + CoA</text>
            <dbReference type="Rhea" id="RHEA:19709"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57970"/>
            <dbReference type="ChEBI" id="CHEBI:58342"/>
            <dbReference type="ChEBI" id="CHEBI:58608"/>
            <dbReference type="EC" id="2.3.1.51"/>
        </reaction>
    </comment>
    <comment type="domain">
        <text evidence="2">The HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.51" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003841">
        <property type="term" value="F:1-acylglycerol-3-phosphate O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004552">
        <property type="entry name" value="AGP_acyltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00530">
        <property type="entry name" value="AGP_acyltrn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="2" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="domain" description="PlsC" evidence="4">
        <location>
            <begin position="77"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD89730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="244" mass="28414" checksum="E76ADA2C3200F625" modified="2019-11-13" version="1">MRVLKIIFWVVYRIWFYVLVGLPIIVLLPFLMVSILKESWYPFFFKLARLWARSILFGMGFRVKIERDEVPDPKKSYMFIANHTSMADIMLMLVTVKNPFVFVGKAELVKIPLFGFFYKRTCILVDRNNPQSRQAVFKRAQRRLHQGLSICIFPEGGVPDEHVVMDSFKDGAFRLAINHQIPIVPIAFADNKKRFSFTFLSGSPGQMRVKMLPFVATEGLTSKDAKTLNQKLRETIFQQLKKFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIP2</accession>
    <name>A0A5C6ZIP2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">MarR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_04820</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="157" mass="18095" checksum="3ACDBD133F986880" modified="2019-11-13" version="1">MSKLEEKQELIESIGIQMEQRLNVSPLAARIYALLALSSYEGLSFDTIRNSIGSSKSSTSVNLNVLIQLKYVEYRTKSGDRKRYFRVAKYFQISALEQQSQTLATDIKMVEKINDFNKNHYPEKFDNEQSLGQLTIDYLLKMQSLVKNTIDQLKKLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIS0</accession>
    <name>A0A5C6ZIS0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Aminoacyl-tRNA hydrolase</fullName>
            <ecNumber evidence="4">3.1.1.29</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_08545</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the prokaryotic/mitochondrial release factor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.29" evidence="4"/>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004045">
        <property type="term" value="F:aminoacyl-tRNA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003747">
        <property type="term" value="F:translation release factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045853">
        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75620">
        <property type="entry name" value="SSF75620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00745">
        <property type="entry name" value="RF_PROK_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RF_PROK_I" evidence="3">
        <location>
            <begin position="17"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="99"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="134" mass="15646" checksum="44146020272A935E" modified="2019-11-13" version="1">MFDEQAILSELQFKAVRSSGAGGQHVNKTASKVELTFDLENSQFLSEHQKMLLKKNLQSRLTNNIVLMMQCGESRSQHQNKSIIIKRFLDLLKDNLVEEKERIPTKTPKRAKRRRLKNKRIKSEKKANRKPPEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIW8</accession>
    <name>A0A5C6ZIW8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_08875</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="255" mass="30656" checksum="F6A081F970F2F47A" modified="2019-11-13" version="1">MPKIIENKIIEVFKERSSFDRDELYHFYLDFEPDLKESTFSWRIYDLKKKDIIKTIGRGLYVISAKPKYKPVLTENVLKIARKTTKRFEDITYCIWESQWLNEFTRHQTSNQMIVVEVEKEFTESLYYFLNDSLRMDFFLNPGEKEIEFYISESTVPVVIKRLVTRAPISKLKDKKTVVPIATLEKIMVDLFADDNLFHFYQGSELIYIFERILDRYSINLTKLFGYAKRRKKEQEIKQFISKHIPNFLEGIQYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ72</accession>
    <name>A0A5C6ZJ72_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_11700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="127" mass="14755" checksum="5D21F97176033A7B" modified="2019-11-13" version="1">MCLTFFNCKEEKPAEYEWKTINVTATAFNSTRRQTNNNPHITAFGDSLKPGLRYIAVSRNLLRLGLTHNTPVNIEGLEGTYLVKDKMHYRWKNKIDVYMGTDVEAARNWGRKRVNISYRVKIKTDSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJD0</accession>
    <name>A0A5C6ZJD0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cupin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_04690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="1">
        <location>
            <begin position="42"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="120" mass="13582" checksum="065ED330C70E18AE" modified="2019-11-13" version="1">MKPYTIQKQPFAVPTTDGKVINEHFGLATDGNKEISIAHMKAPAGWSEPFQTPQFDEYTLILKGKKQFIIDHETIILKAGQSIKIDKNTKVQYSNPFTEVCEYISICTPAFSMDLVNRED</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJE0</accession>
    <name>A0A5C6ZJE0_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Cell division protein FtsA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 8" type="primary">ftsA</name>
        <name evidence="8" type="ORF">ESY86_09405</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Self-interacts. Interacts with FtsZ.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
            <orientation evidence="5">Cytoplasmic side</orientation>
        </subcellularLocation>
        <text evidence="5">Localizes to the Z ring in an FtsZ-dependent manner. Targeted to the membrane through a conserved C-terminal amphipathic helix.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the FtsA/MreB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009898">
        <property type="term" value="C:cytoplasmic side of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02033">
        <property type="entry name" value="FtsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020823">
        <property type="entry name" value="Cell_div_FtsA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003494">
        <property type="entry name" value="SHS2_FtsA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02491">
        <property type="entry name" value="SHS2_FTSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003101">
        <property type="entry name" value="FtsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00842">
        <property type="entry name" value="FtsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01174">
        <property type="entry name" value="ftsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 5 6" id="KW-0132">Cell division</keyword>
    <keyword evidence="1 5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FtsA" evidence="7">
        <location>
            <begin position="7"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR003101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD89250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="445" mass="48968" checksum="FB8771A5E020FFAE" modified="2019-11-13" version="1">MEDNKISVGLDLGTTKIVVMIGRKNEYGKAEILGIGKAKSLGVHRGVVNNITQTIQSIQQAAQEAEAEAGIKIERITVGIAGQHIRSLQHSDYITRPNPETVIDEADIDRLINQVHKLVMLPGEEIIHVLPQEFKIDGQAEIKEPIGMYGGRLEANFHVVVGQVSSIRNVGRCVKSSGLELENITLEPLASANAVLSQEEKEAGVALIDIGGGTTDLAVFKDGIIRHTAVIPFGGNVVTEDIKEGCSIIEKQAELLKIKFGSAWPGENKDNEIVSIPGLRGREPKEITLKNLSKIIHARVVEIIEQVYVEIKNYGHEEQKKKLIAGIVLTGGGSQLKHLKQLVEYITGMDTRIGFPNEHMAGDSDDEIASPLYATAVGLVMDGLKRQERKRIEKQEEIDAASEEELKDEVPLELEEDVAPVQKRERKSFLDKLTERVKDFLDNAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJV8</accession>
    <name>A0A5C6ZJV8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_10615</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="252" mass="29529" checksum="57E197C341C526A7" modified="2019-11-13" version="1">MESKFNLDSFLKLSDAANFYLEESFKYVNEIFTKDLEKLVLVEQLKDVQFSEEDLKLIEEGGIPKGSITYLRSDKRLVQFLTVETLNEILNAHNEVNEIVSNKKPKIPKKHVIKSIQILGHISNLALFVEVLTNRHLLFLNHNDIIDNFVYNQLSEGKILNIIIFICRDELENGSIKLDSIKHLFRHRNKAVHHTPKNADELKVKVEDLFQIWNQIIKLIAIYEDREKFNENKFSTKLKVEKGIIQDSYIFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK02</accession>
    <name>A0A5C6ZK02_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19580">
        <property type="entry name" value="Exo_endo_phos_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endo/exonuclease/phosphatase" evidence="1">
        <location>
            <begin position="12"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF19580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="321" mass="37399" checksum="63E1B738A0403F3F" modified="2019-11-13" version="1">MQTETSNSKSHTLAFYNLENLFDYREGSAVFDTGFIPYSERRWNKKRYEDKIHKLGQVISQIGDPSEEMLPAIIGLAEVENETVLHDLTQSKHLRHHNYGFVHFDSQDERGINVALLYHRDVFELMHTETFSVYLEKEPGVQYFTRDILLVSGELHSEKIHLIVNHWPSRFEGLESSAIKRMAVAKKVLKIIEQLQFDDPKAKILVMGDFNDDPDNDSMKYLVDEAGLVNAMETLRSYSRGSHKHRFKWHLFDQILLTSNFFESRSKQLKFDKADIYDPQYLKAYEGKFKGQPFGTFVGTKYKGGFSDHFPVYLRLKLVTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK35</accession>
    <name>A0A5C6ZK35_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Conjugal transfer protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023220">
        <property type="entry name" value="T4SS_VirB5-domain"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022761285" evidence="1">
        <location>
            <begin position="16"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="184" mass="20984" checksum="F0A68EA2FFA37E17" modified="2019-11-13" version="1">MTVALTLFMSGNASAQGMPTYDNTNFISLVKQLLESGKQTAQMIKSVKFLKDAKEAIEQVSSVVQQLNAVQEIADNNQRLINVMQNDLQDILNSPYIKPDEVSRVVESFDAIVQNSLETVDFIDEVLSSDYLKMSDAERAEVLKEKELESKEMVSNITTKTRRYKDIISFRKMQDKINNRETEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK82</accession>
    <name>A0A5C6ZK82_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">STAS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08805</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="STAS" evidence="1">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="93" mass="10444" checksum="BFAF6CF1195D8DE6" modified="2019-11-13" version="1">MTLEIRNDNNYFKLKGILNKRNLAFFKAEIDAVFETFNTITLNIEDLVGIDRHGVKAISELQNQALANNKRLSVIGLGNNKVYSSFKAAEKVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK88</accession>
    <name>A0A5C6ZK88_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">OmpA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_03295</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006664">
        <property type="entry name" value="OMP_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01021">
        <property type="entry name" value="OMPADOMAIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022749082" evidence="3">
        <location>
            <begin position="20"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="domain" description="OmpA-like" evidence="4">
        <location>
            <begin position="524"/>
            <end position="645"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="645" mass="73772" checksum="F103DA64DFE0075B" modified="2019-11-13" version="1">MKSKFLILIFALSSTFMIAQERLADKFFSNYGYVKATELYQEVLKKGDTTLNVLTRLGDCYYNNSNSEKAAFWYAKAFDKYGQDKISPEYMYKYIQSLRSQNEYEKAEDWMAKFMIVQNDDSRTEEYNPENIVKYDYLNDAERNRVVTLKPAAFNSANSDFGAYIKDNMLYFASARNTEGNKIYGWNDEPFLDLYQLAITRDQDSLSFGPAELMPSEQVNSKYHEASLAITNDGKTMYFTRDNMSGSKRIDYDKKGTTHLKLYKASLVEGQWESIIELPFNDISYSNGHPALSPDNKKLYFVSDREGGFGNTDLYVVDIKGNDSYGEPQNLGAKINTEGREMFPYVSQDSTLYFSSDGRLNLGFLDIFKSNVLKDETAEPLNLGAPYNSSYDDFAYFNTLPSDEKETGYTGYFSSNRPGGNGSDDIYMFDTRICYATIKGFSRKSVDNTILPGVTVQLIDEVGKVISEVKTGVDGAYEFEANCNYTYTVLGTIKDHKPDQISVTTTNKTSEIENADLFLEPLINDNQIVINPIFFDFDKAEIRTDAQYELENIVDVLRAHPKMIIRIESHTDSRGRDYYNMKLSDRRAKATEDYILSRGIAEDRVESAIGFGETQLLNECSNDVKCTEEQHQLNRRSYFYILKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKF6</accession>
    <name>A0A5C6ZKF6_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA uridine(34) hydroxylase</fullName>
            <ecNumber evidence="1">1.14.-.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">tRNA hydroxylation protein O</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">trhO</name>
        <name evidence="3" type="ORF">ESY86_07615</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes oxygen-dependent 5-hydroxyuridine (ho5U) modification at position 34 in tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>AH2 + O2 + uridine(34) in tRNA = 5-hydroxyuridine(34) in tRNA + A + H2O</text>
            <dbReference type="Rhea" id="RHEA:64224"/>
            <dbReference type="Rhea" id="RHEA-COMP:11727"/>
            <dbReference type="Rhea" id="RHEA-COMP:13381"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:136877"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the TrhO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.-.-" evidence="1"/>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00469">
        <property type="entry name" value="TrhO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022111">
        <property type="entry name" value="Rhodanese_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020936">
        <property type="entry name" value="TrhO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040503">
        <property type="entry name" value="TRHO_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12368">
        <property type="entry name" value="Rhodanese_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17773">
        <property type="entry name" value="UPF0176_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="144"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="354" mass="40771" checksum="1A619C719F1BC83F" modified="2019-11-13" version="1">MQLYNTLSAKERAELIAQAGQERLTLSFYAYAKINAPRAFRNQLFLAWNPLEVLGRIYVAHEGINAQLSVPAEHFQDLKTHLDSIPFLEDVRINIAIEHDNFAFLKLKVKVRDKIVADGLDDDTFDVTNKGIHVDAEAFNSLMEDPNTILVDMRNHYESEIGHFKNAITPNVDTFRESLDIIEEDLKDHKEDKNLVMYCTGGIRCEKASAYYKHKGFKNVFQLEGGIIHYVRQVEADQMENKFIGKNFVFDQRRSERISDDVIAHCHQCGQPADTHVNCANDACHLLFIQCEDCQQKMENCCSSTCMEVNQLPKDEQKDMRKGQGNSNDIFKKGRAEHLSYKKDLRNIFENFQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKG6</accession>
    <name>A0A5C6ZKG6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Acyl-CoA thioesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_07680</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the acyl coenzyme A hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016790">
        <property type="term" value="F:thiolester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040170">
        <property type="entry name" value="Cytosol_ACT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033120">
        <property type="entry name" value="HOTDOG_ACOT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11049">
        <property type="entry name" value="PTHR11049"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51770">
        <property type="entry name" value="HOTDOG_ACOT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HotDog ACOT-type" evidence="4">
        <location>
            <begin position="7"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD89655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="169" mass="18872" checksum="C61D668F1795A190" modified="2019-11-13" version="1">MEPRTAFQSKTIMTDMVLPSETNPINNLFGGELLARMDRAASIAARRHSRRIVVTASVNHVAFNRSVPLGSVVTIEAKVSRAFTSSMEVYMDVWIEDRESGECIKANEAIYTFVAVDDTGRPVKVPDLLPETELEKQRYEAALRRKQLSLVLAGKMKPSEATELKALFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKN5</accession>
    <name>A0A5C6ZKN5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Endoribonuclease YbeY</fullName>
            <ecNumber evidence="7">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 8" type="primary">ybeY</name>
        <name evidence="8" type="ORF">ESY86_08060</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the endoribonuclease YbeY family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="7"/>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00009">
        <property type="entry name" value="Endoribonucl_YbeY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023091">
        <property type="entry name" value="MetalPrtase_cat_dom_sf_prd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002036">
        <property type="entry name" value="YbeY"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02130">
        <property type="entry name" value="YbeY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00043">
        <property type="entry name" value="TIGR00043"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6 7" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="7">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD89725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="135" mass="15958" checksum="F2E6BB26D98CC755" modified="2019-11-13" version="1">MINFNYETEFKLTNETNLAAWLTSVIASEEHKEGEINYVFCDDDYLHKLNLEFLEHDTLTDIISFDYSIGKELHGDIYISVERVRENASEYSTDFEEELQRVMVHGILHYCGYKDKTESEQNAMRAKEDLYLIRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKN7</accession>
    <name>A0A5C6ZKN7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Copper-translocating P-type ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">ESY86_02735</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006825">
        <property type="term" value="P:copper ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017969">
        <property type="entry name" value="Heavy-metal-associated_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006122">
        <property type="entry name" value="HMA_Cu_ion-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045800">
        <property type="entry name" value="HMBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19335">
        <property type="entry name" value="HMBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="SSF55008"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00003">
        <property type="entry name" value="TIGR00003"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01047">
        <property type="entry name" value="HMA_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0186">Copper</keyword>
    <keyword evidence="5" id="KW-0187">Copper transport</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="341"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="373"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="406"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="444"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="598"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="626"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="944"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="972"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="12">
        <location>
            <begin position="2"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="12">
        <location>
            <begin position="84"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="12">
        <location>
            <begin position="168"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="228"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TXD90891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="999" mass="108621" checksum="6FEBD9E9C419DE2F" modified="2019-11-13" version="1">MKHSYHIQGMTCNGCRSHVEKTLSEVDGVTNASVNLEKSEATIEMEAHIPIETFQKALQEDGGSYSIHRPKEEEEEEEENGMMKHTYHIHGMTCNGCRSHVEKTLSEVEGVTNASVNLEKSEATIEMEAHIPIETFQKALQEDGGSYSIHKPKEEEEEEEEEENGLMKHTYHIQGMTCNGCRSHVEKTLSEVDGVTNASVNLEKSEAIIEMESHLPIETFQKALQEDGGSYSIHEPGAHNPPSEKKAAKSKGKGTGTFYCPMHCEGDKTYDKPGDCPVCGMDLVEEQNLSATTSEQWTCPMHPEIVEDEPGACPICGMDLVPMQPDSSSEEKTYKNLLKKFWVAVAFTLPIFLIAMSEMIPNNPLYDMMEQKWWNWIQFGLSIPVVFYATWMFFERAYRSIKTWNLNMFTLIGIGAGVAWLFSVFGMLFPDFFPEQFKTDSGAVHVYFEAATVILTLVLMGQVLEARAHSKTNSAVKELLKLAPNKAIKVVDGTEEEVSIDQIQKGDILRVKPGDKIPVDGVITEGHTTVDESMISGEPIPVDKAESDNVSSGTINGNQSFLMKAEKVGSDTLLSQIIHMVNDASRSRAPIQKLADTVSGYFVPVVVGISIITFAVWAIWGPEPAYVFALVNAIAVLIIACPCALGLATPMSIMVGVGKGAQNGVLIKNAEALEKLDKVDTLIIDKTGTITEGKPTVEKIGVFGANFSESEILKFIASLNSSSEHPLAEATVKYGKAQKTEISKTENFSAVTGKGVEGTVDGKKLDLGNAKMMAYAKATISTEMETEVQSFQKQGKTVSYLAVDGEVSGYVVIGDKIKKTSAKAIKELQDKGIAVIMLTGDNHDTAQAVASELNLADFKAGMLPEDKLKEVTKLQEQGKVVAMAGDGINDAPALAKSDVGIAMGTGTDVAIESAMITLVKGDLHGIVKAKNLSHAVMRNIKQNLFFALIYNTLGVPIAAGVLFPFFGILLSPMIAALAMSFSSVSVIANALRLKTKKIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL07</accession>
    <name>A0A5C6ZL07_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UDPG_MGDP_dh_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07865</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001732">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03721">
        <property type="entry name" value="UDPG_MGDP_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDPG_MGDP_dh_N" evidence="1">
        <location>
            <begin position="2"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="87" mass="9529" checksum="232AF3683D65AC9E" modified="2019-11-13" version="1">MVTVAALAETGNEVLCIAIEEQKVKNTNEGSIDEPHLHLLSARTIKAGRLKLSTSFNEGLEHAEIIFFALPRPEARDGSANHKSFLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL18</accession>
    <name>A0A5C6ZL18_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methionyl-tRNA formyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_07915</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016742">
        <property type="term" value="F:hydroxymethyl-, formyl- and related transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005793">
        <property type="entry name" value="Formyl_trans_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002376">
        <property type="entry name" value="Formyl_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036477">
        <property type="entry name" value="Formyl_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011034">
        <property type="entry name" value="Formyl_transferase-like_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02911">
        <property type="entry name" value="Formyl_trans_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00551">
        <property type="entry name" value="Formyl_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50486">
        <property type="entry name" value="SSF50486"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53328">
        <property type="entry name" value="SSF53328"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Formyl_trans_N" evidence="1">
        <location>
            <begin position="46"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="Formyl_trans_C" evidence="2">
        <location>
            <begin position="194"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="293" mass="32950" checksum="90124B7D66F2F34D" modified="2019-11-13" version="1">MLRIGVLCSGNLGLDTLSKIVKEQSVSFVLTDNNSSDIIEFCETHNIPYYAGNPRNGKASDFIKTFSVDVIASINYLFLIEADIIQHANLLTFNIHGSLLPKYRGRTPHVWAIINGETKAGITAHVIDAGCDTGKIIHQIEVPIEIEDTGANMLLKYAELYYPLVERVLEDLSSNQLKLITQDEDEASFYGKRTPADGEIDWNWPKETIRNWVRAQAYPYPGAFTFYGRDKIIIDKISFSEEIIDNSQPNGTLVKVKPKTLVKTKNGAVQLETIRPENCTFAEGKLFSNENRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL21</accession>
    <name>A0A5C6ZL21_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TlpA family protein disulfide reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_04880</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013740">
        <property type="entry name" value="Redoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08534">
        <property type="entry name" value="Redoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="73"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="210" mass="23317" checksum="820A502AC56AEEB3" modified="2019-11-13" version="1">MDKNKKSKDTKKTWIQYGVFAILAVVLYATGLHTEVIGFAQRGLLATGLMNPDVAGIAQAQNNENRSETANITKLTKADFNFQMIDRDGNTKSLEALKGKVIFMNFWATWCPPCIAEMPSIDKLHEEMGDDVAFVILSFDTDFEKAKAFDKRKGYDLPIYAPVSALPAMFESNALPTTYVIDAAGNLALTHKGMADYDNPEFKKFLNGLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL49</accession>
    <name>A0A5C6ZL49_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06835</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydrolase_4" evidence="1">
        <location>
            <begin position="28"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="289" mass="32516" checksum="F1792CD2F012D19B" modified="2019-11-13" version="1">MQEQPIHVQTKDDVSIAVWKSNPKQSNGKVVFLTHGAFSNRQIFNGIVGALTQNGFTCWSMEWRNHGESEHSPSKFNLETVAEFDLSATLNFLVNKQGLKSFDCITHSGGGLVLTMFLIKNPSYRASIKSISMFGVQAFGAGSKLKNRMKIFAGKYVSAMLGKVPSKPAGSIENSESYHTLKQWFDWNLKKNFVGEDGFDYREKMKSIQIPILSICAKGDHFIAPKEGCQQYLEAFENPQNKLIYFALENGNLEDYSHSRIILSRNSEKEIYPVVLKWIHESASSKSKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL95</accession>
    <name>A0A5C6ZL95_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phage_int_SAM_5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_00550</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025269">
        <property type="entry name" value="SAM-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13102">
        <property type="entry name" value="Phage_int_SAM_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phage_int_SAM_5" evidence="2">
        <location>
            <begin position="42"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD91118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="146" mass="17445" checksum="78883AEC330A1012" modified="2019-11-13" version="1">MNNFWNKERTANAIKARYLGLDESHKTLNQRIAYHSASMVGILKYGTMKKYHTTGRCLLKYLSKVSKADDIYLKQLNYRFIGEFEQFLRAFRNPKKELVRSNNGIIKHLKRFKKMGNLAVKLLWFPKNPFNQFQLKYNKFDRQFLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLA6</accession>
    <name>A0A5C6ZLA6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ParB/RepB/Spo0J family partition protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_00620</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ParB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041468">
        <property type="entry name" value="HTH_ParB/Spo0J"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004437">
        <property type="entry name" value="ParB/RepB/Spo0J"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003115">
        <property type="entry name" value="ParB/Sulfiredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036086">
        <property type="entry name" value="ParB/Sulfiredoxin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17762">
        <property type="entry name" value="HTH_ParB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02195">
        <property type="entry name" value="ParBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00470">
        <property type="entry name" value="ParB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110849">
        <property type="entry name" value="SSF110849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00180">
        <property type="entry name" value="parB_part"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ParB" evidence="3">
        <location>
            <begin position="41"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD91128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="299" mass="34062" checksum="A00D5D9D2B21DBDE" modified="2019-11-13" version="1">MAKATKKQALGRGLSALLKDPSNDINSIQDKNADTIIGNIVELDIEAIEINPFQPRTNFNEETLRELASSIRELGVIQPITVRKMEFNKFQLVSGERRFRASKLIGLQTIPAYIRIANDQESLEMALVENIQRQDLDPIEIALSYQRLIDEIALTQEQMSERVGKKRSTIANYLRLLRLDPIIQTGMRDGFISMGHGRAIINIEDQEKQLEIYEKIISDKLSVRATETLVKAYQNPKETKAPEPEELPKFVKKGIKDFSEYFGHKINVKVSKNGKGQITIPFHSEEDFNRIKKLVQSAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLA8</accession>
    <name>A0A5C6ZLA8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="99" mass="11026" checksum="C69E0BD087564679" modified="2019-11-13" version="1">MTNTKYIKLAGSILLDAVGYVTFLIPGVGEFGDVIWAPASAYIMTKMYKGKKSRIAATISFVEEALPFTDVIPTFTLMWLYVYVFSAEKPSEEQTIDVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLB0</accession>
    <name>A0A5C6ZLB0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_03510</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="201" mass="22568" checksum="3509F369CEEC2AEF" modified="2019-11-13" version="1">MTTAIITGDIIKSQGQDPEHWMETLKSTLSNFGKSPKNWELYRGDSFQLETTPKTALYAALLIKAHLKQYSNLEVRLAIGIGEKTFETNKITESNGSAFVNSGICFENLKKNTLAIKTQHEHLNHSLNLMFELASLTIANWTSAVAELIAYALAHPDHNQQRIAKHQKTTQSNVSQGLKRGGFDELSKLLQYYQTQIETLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLF6</accession>
    <name>A0A5C6ZLF6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycoside hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_02555</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032640">
        <property type="entry name" value="AMPK1_CBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16561">
        <property type="entry name" value="AMPK1_CBM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMPK1_CBM" evidence="1">
        <location>
            <begin position="22"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="99" mass="11042" checksum="E91882C06AFA503A" modified="2019-11-13" version="1">MAITKQYLKSKPVCKVTFTVPTEGAKTVSVLGSFNDWDEQKAVKLKKLKDGSFRGAVNLEKDKSYEFRYLVDGTFTNDEQADALAWNDFAGAENSVLNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLW0</accession>
    <name>A0A5C6ZLW0_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Prephenate dehydratase</fullName>
            <ecNumber evidence="3">4.2.1.51</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">ESY86_02130</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H(+) + prephenate = 3-phenylpyruvate + CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:21648"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:18005"/>
            <dbReference type="ChEBI" id="CHEBI:29934"/>
            <dbReference type="EC" id="4.2.1.51"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-phenylalanine biosynthesis; phenylpyruvate from prephenate: step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.51" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00121">
        <property type="reaction ID" value="UER00345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004106">
        <property type="term" value="F:chorismate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004664">
        <property type="term" value="F:prephenate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009094">
        <property type="term" value="P:L-phenylalanine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008242">
        <property type="entry name" value="Chor_mutase/pphenate_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001086">
        <property type="entry name" value="Preph_deHydtase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00800">
        <property type="entry name" value="PDT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001500">
        <property type="entry name" value="Chor_mut_pdt_Ppr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51171">
        <property type="entry name" value="PREPHENATE_DEHYDR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0584">Phenylalanine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prephenate dehydratase" evidence="9">
        <location>
            <begin position="46"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="10">
        <location>
            <begin position="237"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="site" description="Essential for prephenate dehydratase activity" evidence="8">
        <location>
            <position position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001500-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD90782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="317" mass="35798" checksum="0B635937277D1E99" modified="2019-11-13" version="1">MKIGTFFLPYSLQSNFKLKQNTIILSKSHPETTAVKQTQPVKTIKSVAIQGVKGSFHHIVSQQYFDTSVKVNECMTFAEAVDSLLTGQSDAVIMALENSIAGSILPNYALIDDHNLHIIGEHYLDIQHCLMALPGQEIADIREVYSHPMALLQCKAFFRKHPHIKLIEDKDTAEVAERIQKKQLKNVAAIASQLASEFFELEILEHSIQTIKNNETRFVIVEREVSNLDTAHFNKASLKFELDHKRGSLAALLNVLSDCKLNLTKIQSLPKIETPWKYAFFVDVTFESYSDFEKAKAIVALMAQDFKILGEYKNTSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLW1</accession>
    <name>A0A5C6ZLW1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="66" mass="7506" checksum="7E2D6033071DA72F" modified="2019-11-13" version="1">MASNLANPSRMKIKANTVFIYIGLFITSYIILFFDFFIGFLIQLVLLIFGIVLALNILINHLKSNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLW8</accession>
    <name>A0A5C6ZLW8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphotransferase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_01570</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05154">
        <property type="entry name" value="ACAD10_11_N-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041726">
        <property type="entry name" value="ACAD10_11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002575">
        <property type="entry name" value="Aminoglycoside_PTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01636">
        <property type="entry name" value="APH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="APH" evidence="1">
        <location>
            <begin position="40"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="359" mass="41225" checksum="94081DE9270F3260" modified="2019-11-13" version="1">MSNEKNLKSVREGEELNEAKLKAFLLEHSLITHENTELSVKQFTNGYSNLTYLLQIENKEFVLRRPPFSAPKRGHDMGREFKVLQHLNPVYDKSPKVFVFNEDPKIIGAPFYIMEKVNGEILTAKSAHEKQVSPDEFKTISDTWIDAFVEFHNIDYKAAGLSEFGKPEGYVERQVSNWGKQYLAAATDEVPSAQKVMTWMSENQPKKYDHTLIHNDFKYDNVVFKDDSWKTISAILDWEMCTLGDPMMDLGTSLGYWTTANDPEFMKQGLPSSTVMKGNPSRTEIVQLYALKSGRNIDNLTFYYAYGLFKIAVIAQQIYYRYKHGHTSDPKFANLNKASALCCNTAWQAIQKNQIDNLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLY0</accession>
    <name>A0A5C6ZLY0_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">N-acetyl-gamma-glutamyl-phosphate reductase</fullName>
            <shortName evidence="4">AGPR</shortName>
            <ecNumber evidence="4">1.2.1.38</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">N-acetyl-glutamate semialdehyde dehydrogenase</fullName>
            <shortName evidence="4">NAGSA dehydrogenase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">argC</name>
        <name evidence="7" type="ORF">ESY86_02250</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the NADPH-dependent reduction of N-acetyl-5-glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>N-acetyl-L-glutamate 5-semialdehyde + NADP(+) + phosphate = H(+) + N-acetyl-L-glutamyl 5-phosphate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:21588"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29123"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57936"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.2.1.38"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 3/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.38" evidence="4"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00108"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003942">
        <property type="term" value="F:N-acetyl-gamma-glutamyl-phosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00150">
        <property type="entry name" value="ArgC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023013">
        <property type="entry name" value="AGPR_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000706">
        <property type="entry name" value="AGPR_type-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000534">
        <property type="entry name" value="Semialdehyde_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01118">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00859">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01850">
        <property type="entry name" value="argC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01224">
        <property type="entry name" value="ARGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0521">NADP</keyword>
    <keyword evidence="3 4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Semialdhyde_dh" evidence="6">
        <location>
            <begin position="3"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="active site" evidence="4 5">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD90802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="325" mass="36204" checksum="8B7540E47759FD8C" modified="2019-11-13" version="1">MIGVGIVGGAGYTAGELIRLLLNHKEAKLDFVYSTSNAGNKLSKVHQDLVGSTDLKFSSDLNPEVDVLFLCLGHGHSKAFLESNAFSESTKIIDLSNDFRLEHDQHFKGMDFIYGLPELFKEDIKTANYIANPGCFATAIQLAILPLADIHLLKADIHVNAVTGATGAGTALSETTHFTYRDNNFSHYKSFTHQHLGEINERIKQLQTNFSSEVLFIPNRGNFSRGIFATAYTNFEGSLQEAKRLYLEFYKDAAFTVVCEEDIHLKQVVNTNKCLLHLQKHNNKLLITSCIDNLLKGASGQAVQNMNLMFGFEETEGLRLKANYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLY3</accession>
    <name>A0A5C6ZLY3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutamate--cysteine ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_01650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-cysteine + L-glutamate = ADP + gamma-L-glutamyl-L-cysteine + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13285"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58173"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.2"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004357">
        <property type="term" value="F:glutamate-cysteine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042398">
        <property type="term" value="P:cellular modified amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006336">
        <property type="entry name" value="GCS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04107">
        <property type="entry name" value="GCS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="408" mass="46231" checksum="C2F97F7D8EB7802D" modified="2019-11-13" version="1">MPKSYHLFEVYGIELEYMLVSKTDLKVQPIVDQLLSLKNGELTAELENGSVAWSNELVAHVVEIKTNGPTADLKNLAKAFHKNIVEINALLAPLDAKLLPTAAHPFMDPLTETRLWKHSYSEIYALYNRIFNCKGHGWSNVQSTHINLPFYDDAEFEKLHAAIRLVLPLIPSLCASSPILDGKLTGFKDTRLEYYKTNQQEIPEMTGLVIPEAVFNKKEYSERIFEPIKNAIRPRDTENILDHHFLNSRGAIARFDRNAIEIRLVDIQECPKADVAICSLIIATLQALVNGDFCDLETQKAWHEKDLYEILELGIKHGENANITNMDFLALFGISEAMTANRLWDHIFAYVAHYMDNSFLSTIIQILEHGTLASRIEKALAQDASEAKIALVYEQLATCLHENKLYLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMA9</accession>
    <name>A0A5C6ZMA9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2520 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018931">
        <property type="entry name" value="DUF2520"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037108">
        <property type="entry name" value="TM1727-like_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10728">
        <property type="entry name" value="DUF2520"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2520" evidence="1">
        <location>
            <begin position="123"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="252" mass="28492" checksum="0B1CDDDC1BD51334" modified="2019-11-13" version="1">MTSVVILGAGNVAQHLYRAFSNSETVNVAQWYNRHLDPIKSFKNDVPVTDDISQLFEADLYIIAVSDDAIAEVSQQLPFENRLVVHTSGSASPYDIDQKNRRGIFYPLQSFSKAAEMDFTTVPICLETLVKTDYAFLKTVARAISNITKRINSDQRAALHLAAVFVNNFTNQLYRVAHEITESQGAEFDLLKPLILETAQKVQELSPYRAQTGPAIRNDKKTIKRHLKLLTNEQHKTIYKLMTQAIKQTHGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMF9</accession>
    <name>A0A5C6ZMF9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glycerol kinase</fullName>
            <ecNumber evidence="5">2.7.1.30</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">ATP:glycerol 3-phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Glycerokinase</fullName>
            <shortName evidence="5">GK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">glpK</name>
        <name evidence="9" type="ORF">ESY86_01325</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate</text>
            <dbReference type="Rhea" id="RHEA:21644"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17754"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.30"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="5">Inhibited by fructose 1,6-bisphosphate (FBP).</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the FGGY kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.30" evidence="5"/>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00618">
        <property type="reaction ID" value="UER00672"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004370">
        <property type="term" value="F:glycerol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019563">
        <property type="term" value="P:glycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006072">
        <property type="term" value="P:glycerol-3-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00186">
        <property type="entry name" value="Glycerol_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000577">
        <property type="entry name" value="Carb_kinase_FGGY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="Carb_kinase_FGGY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018483">
        <property type="entry name" value="Carb_kinase_FGGY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
        <property type="entry name" value="Carb_kinase_FGGY_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005999">
        <property type="entry name" value="Glycerol_kin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02782">
        <property type="entry name" value="FGGY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00370">
        <property type="entry name" value="FGGY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000538">
        <property type="entry name" value="GlpK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01311">
        <property type="entry name" value="glycerol_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00933">
        <property type="entry name" value="FGGY_KINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00445">
        <property type="entry name" value="FGGY_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0319">Glycerol metabolism</keyword>
    <keyword evidence="5 6 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FGGY_N" evidence="7">
        <location>
            <begin position="4"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="FGGY_C" evidence="8">
        <location>
            <begin position="260"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="82"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="243"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="12"/>
            <end position="14"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="12"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="265"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="308"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="312"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="409"/>
            <end position="413"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD91256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="497" mass="55174" checksum="BCB909FDF68DFBE8" modified="2019-11-13" version="1">MEQYILALDQGTTSSRAIIFDKKGNIFSVAQKEFTQYFPKPGWVEHDPAEIWATQAGVAAEATTKKGLNGKNIAGIGITNQRETVVVWDRKTGDPVYNAIVWQDKRTADYCEQLKDEGKAEMIQKKTGLIIDSYFSATKVKWILDNVEGARERAEKGELVLGTIDTWLIWNFTKGELHVTDATNACRTLLFNINTMEWDDELLTLFDIPKSMLPEVKDSSEVYGHTKTTIFASKIPIAGIAGDQMAALYGQMCTDKGMVKSTYGTGCFMLMNIGDKPILSKNNLLTTVAWRINGKTEYALEGSIFIGGAVVQWLRDGLGIIRRSSDVEKLAESVESTEGVYFIPAFAGMGAPYWNQKAQGTIFGITRGTTDAHIARASIEAIAYQTMDILKAMKADAGIPIKELRVDGGASVNNTLMQFQADVLDSITIRPKITETTALGAAYLAGLAVGYWESQEQIHELWEEDMRFEPIKDKKDVENGVKGWYRAVEALQYWTTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMM7</accession>
    <name>A0A5C6ZMM7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Sigma-54-dependent Fis family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_04115</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025943">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025944">
        <property type="entry name" value="Sigma_54_int_dom_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01590">
        <property type="entry name" value="HTHFIS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00676">
        <property type="entry name" value="SIGMA54_INTERACT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00688">
        <property type="entry name" value="SIGMA54_INTERACT_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
            <begin position="7"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="7">
        <location>
            <begin position="145"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="6">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD90561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="442" mass="49644" checksum="024356A96386EBCC" modified="2019-11-13" version="1">MQLRKENILIVDDDINILELLQRHLQSWDYHSFKAVSVKEAVAILRDTKIDLLITDLRMPEIDGFELIKFVSEHYPGLPKLMVTGYPSVQDSLTAIKSGVVGYLTKPFTKAELKSAIAASLAASEKEIAPSSKPSAAKNEAYGDIIGASEKIRDVIQIIERVKNNKATVFIKGESGTGKELVARAIHYQGQFSRAPFIAVNCGAIPENLLESELFGYVKGAFTGADTNRNGFFQAADGGSIFLDEIGNASLAVQSRLLRVLQEKEVIKVGATKSEPVDVRIIAATNSDLGDMIQKKSFREDLFYRLTVVEIEVAPLRQRKDDIVPLVNKFLFKYGVEYKDRYVKIAPEVMAILKRYDWPGNIRELENIIQRAVIMCDKIIELEHLPDHLKYKLKLSSDVLLPLKDIERQYIEKVLRATGNNKTKAAEILQIDRKTIRQKLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMQ1</accession>
    <name>A0A5C6ZMQ1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="188"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="211" mass="23609" checksum="EB6BC07FEEA9DA55" modified="2019-11-13" version="1">MENQYYKSTSISLIVGALLIIVTMALHPSGGSIEHIIKISKTIKIAHSLAIFSLPIILFGFYGLTIRLLDKWRLSILAFIIISFGLVAAMFAAIFNGLTLPYFLNQYSERLEENIEVLKPITNYSFAINIPLDYIFIVACCLTIMIYSIIILLENKLPKWIGYLGVFIVLFSIIGALTGFIFTSLTGFRIFTFSIAAWILSSGVLLYKSSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMT9</accession>
    <name>A0A5C6ZMT9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07105</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045749">
        <property type="entry name" value="DUF6090"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19578">
        <property type="entry name" value="DUF6090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="238" mass="26987" checksum="7632C3093883E965" modified="2019-11-13" version="1">MEKNKTGKYLKYAIGEIVLVVIGILIALSLNNWNESRKNEIVKQQLIEDLIIELQSSKVIIIDAIALGDSLIADGQLYLKHIGSKELTIQIDSLKKLGGFITNGIPYDLNLPIYEDSKSSGKLSMINNKKVLILYAEIMSADIGGTIHRKISNDMYYNGSGWELRKEIGLSEVLSTPNEMLPERFRLSEKEFWEILSRPYTFATLDNSLQMKVNRINYMNRISNGMTEVIALLKDEKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMU6</accession>
    <name>A0A5C6ZMU6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PorT family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_02080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025665">
        <property type="entry name" value="OMP_b-brl_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13568">
        <property type="entry name" value="OMP_b-brl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OMP_b-brl_2" evidence="1">
        <location>
            <begin position="27"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="231" mass="25988" checksum="69EED4E0B80150F3" modified="2019-11-13" version="1">MACFAFCQNKKPPIAEAVKNDTIKVIDTEYREDQFYAGITYNLLGAKPSGVSQSGFSSGYHFGFIRDFPINQRRNVAIGVGLGVTSNSYNNTLLISKAGSKLSYNVLNDEDVSYDKNKFTNYAFELPIEFRWRTSTATSYDFWRIYTGLKIGYVVYSSTKFQSGEGDIQLSGVEDINRFQYGLTFSAGYSNISFYIYYGLNKMFKPEAIVSGSQEPVGMNAIKIGLMFYIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMW2</accession>
    <name>A0A5C6ZMW2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_00910</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="223" mass="25655" checksum="8B0A3684A19F9E29" modified="2019-11-13" version="1">MFTDINSGISVNQFNPRYQRSMVGTQMTQILQMLTAKNSGICANQFDPRHQRSVFGTQMTQILQMFAAKNSGISVNQFDPRYQRSIFGTQTTQILQMFTAKNSGIRANQFDPRHQRSVFGTQMTQIWQMFTDINSGIRANQFDPRHQRSVFGTQMTQIWQMFADINSGISVNQFDPRHQRSVFGTQMTQILQMLAAKNSVIHANQFDPRHQRSIFGTGTTQIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMY9</accession>
    <name>A0A5C6ZMY9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">5_nucleotid_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_01070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009166">
        <property type="term" value="P:nucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008334">
        <property type="entry name" value="5'-Nucleotdase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036907">
        <property type="entry name" value="5'-Nucleotdase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006179">
        <property type="entry name" value="5_nucleotidase/apyrase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575">
        <property type="entry name" value="PTHR11575"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02872">
        <property type="entry name" value="5_nucleotid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01607">
        <property type="entry name" value="APYRASEFAMLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55816">
        <property type="entry name" value="SSF55816"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="5_nucleotid_C" evidence="1">
        <location>
            <begin position="78"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="251" mass="28747" checksum="339EC0588ADB5E3D" modified="2019-11-13" version="1">MNYRPLFFVLFILAFSACKTKNHLHKIEGKQINVSDSIAADQRIEAFIKPYRERVEKDLDSVLAYSVATLSKSDGEYNTAIGNMMADAVYEEVNPVFQKRTGKSIDFVLLNHGGIRAIISKGEITTRTAFEVMPFENSIFVAELKGDQIKELIDYLVIEKRAHPISQLKIVLNADGSLKETSSKEKPLNYTKSYFVATNDYLLSGGDRMNFFKVNDSVYDLNYKVRNVLLDYFKKTDTLRPRIDDRFIKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNR6</accession>
    <name>A0A5C6ZNR6_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dict-STAT-coil domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00440</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015347">
        <property type="entry name" value="STAT_TF_homologue_coiled-coil"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09267">
        <property type="entry name" value="Dict-STAT-coil"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dict-STAT-coil" evidence="1">
        <location>
            <begin position="11"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="89" mass="10149" checksum="EFBD79DB29CA9822" modified="2019-11-13" version="1">MKTHNQPLIILSISILLFASCESVTSKVETQLNQLNDKAIQLDSVINTEMEKINQLDSVINLEDLKIKKLDSLVEKTSSKLDSIWRKHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNW1</accession>
    <name>A0A5C6ZNW1_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Primosomal protein N'</fullName>
            <ecNumber evidence="9">3.6.4.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ATP-dependent helicase PriA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 12" type="primary">priA</name>
        <name evidence="12" type="ORF">ESY86_00115</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the primosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the helicase family. PriA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="9"/>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990077">
        <property type="term" value="C:primosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006269">
        <property type="term" value="P:DNA replication, synthesis of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006268">
        <property type="term" value="P:DNA unwinding involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00983">
        <property type="entry name" value="PriA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005259">
        <property type="entry name" value="PriA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041222">
        <property type="entry name" value="PriA_3primeBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042115">
        <property type="entry name" value="PriA_3primeBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041236">
        <property type="entry name" value="PriA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040498">
        <property type="entry name" value="PriA_CRR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17764">
        <property type="entry name" value="PriA_3primeBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18074">
        <property type="entry name" value="PriA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18319">
        <property type="entry name" value="PriA_CRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00595">
        <property type="entry name" value="priA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 9" id="KW-0639">Primosome</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="292"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="11">
        <location>
            <begin position="555"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="9">
        <location>
            <begin position="524"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="9">
        <location>
            <begin position="551"/>
            <end position="567"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TXD91041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="817" mass="93561" checksum="036FBC8D7F251D6F" modified="2019-11-13" version="1">MAHFINVILPIPLEKSFTYAITAAEADFLKPGMRVSVPFGKTKIYTGLVDTIHTQAPLIYEAKQIHQILDEQALVTTTQLKHWQWIANYYMCSVGEVMRAALPNAFILESETIITKKEDSVIDDMALDDDEFVVFEALQHQSSLKLQDLMSILDKKNVLPIIKRLLDKKVINVQEEIYEKYKPKLVRYVKMASAFTSEKKLQELLEELSRAPKQREVIMTLFSISAQTKKPIKVSDLSSESDASSSIIKTLIDKGVLEEYHIQMDRVQYDGDDNEASKSLNEHQETALKQISETFETQDITLLHGVTSSGKTEIYVKLIEDQLAKGKQVLYLLPEIALTTQLVDRLQIYFGAQVAVFHSKYSSNERVEIWNNVLQNEANAQIILGARSSVFLPFRNLGLVIVDEEHETSFKQFDPAPRYHARDTAIVLARLFKAKTLLGSATPSLESYYNAQQGKYGLVELNQRYNNVLMPDIELIDIKDKHKRKRMKGHFSDRLVEEIEETLAAGHQIILFQNRRGFSPIVECNACGHSPQCPNCDVSLTFHQYKNQLRCHYCGYNTIMHKTCEACGGVELDAKGFGTEQIEQEAKVLFPEHTVGRMDLDTTRGKYGYEKIITALEQQEIDILVGTQMLTKGLDFRNVKLVGIMNADNMLNFPDFRAHERSYQLMTQVSGRAGRTKERGKVLIQTYNPYHRILQQVSTNNYKQMFDEQLEDRFAFKYPPIYRMIKITLKHKDYQKVDVGANWYAKSLRTVFGDHVLGPEFPPVARIRNQYLKNILVKIPQKQSLGKTKEAIGKINTSFLAVKDFRPIRVILNVDNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZRD0</accession>
    <name>A0A5C6ZRD0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PorT family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_00745</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025665">
        <property type="entry name" value="OMP_b-brl_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13568">
        <property type="entry name" value="OMP_b-brl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022721819" evidence="1">
        <location>
            <begin position="21"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="OMP_b-brl_2" evidence="2">
        <location>
            <begin position="20"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD91150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="211" mass="22663" checksum="B16B56CC0AD4C5C0" modified="2019-11-13" version="1">MKRISMFAIIAISIIASSNAQEFKLGARAGVNLSSIGGDDTGGVGGLTAFHAGLVMEIQYSDKFSFQPEILYSGQGYTNEFSKTTTGITRSLNETVTLDYVSVPLLAKYFFAKGFSVEAGPQLAYLISAKREFVETVSGGFNASESGSEDYKDSTKSFDYGAALGFSYQIGSGTIMSARYYLGLANIVDIEASDLKRQNNVIQISVGFMLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6Z9U0</accession>
    <name>A0A5C6Z9U0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Barstar family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_20680</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the barstar family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000102">
        <property type="protein sequence ID" value="TXD85992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000468">
        <property type="entry name" value="Barstar"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035905">
        <property type="entry name" value="Barstar-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01337">
        <property type="entry name" value="Barstar"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52038">
        <property type="entry name" value="SSF52038"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Barstar" evidence="2">
        <location>
            <begin position="5"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD85992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="92" mass="11047" checksum="B57E0DB4FD180E1E" modified="2019-11-13" version="1">MRIIEINGNKFSNMKGFYREVESKMTFGLNWKIGRNLNAFNDVLYGGFGVHDVDERYTLKWHRSEKSKSELKYYDRIIEIIKEHENIELQLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZB42</accession>
    <name>A0A5C6ZB42_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">LPS export ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">lptB</name>
        <name evidence="5" type="ORF">ESY86_19380</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000039">
        <property type="protein sequence ID" value="TXD86770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03218">
        <property type="entry name" value="ABC_YhbG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030921">
        <property type="entry name" value="LPS_export_LptB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04406">
        <property type="entry name" value="LPS_export_lptB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="4"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD86770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="247" mass="27720" checksum="07915DB004ECF054" modified="2019-11-13" version="1">MKKLRAENLMKSYNGRKVVKDVSLEVNQGEIVGLLGPNGAGKTTSFYMIVGLIKPNGGNIFLEGTNITKYPMYKRAQNGIGYLAQEASVFRKLSIEDNILSVLQMTKLSKKEQRAKMESLIEEFSLGHIRKSRGDLLSGGERRRTEIARALATDPNFILLDEPFAGVDPVAVEDIQRIIAQLTKKNIGILITDHNVQETLAITDRTYLMFEGSILKAGEPEELANDEMVRKVYLGQNFELRKKKLNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZB80</accession>
    <name>A0A5C6ZB80_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Response regulator transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_17635</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000027">
        <property type="protein sequence ID" value="TXD87256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="5"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="144"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD87256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="210" mass="23624" checksum="3FF2A5653E65206B" modified="2019-11-13" version="1">MNTIKLAIIEDDTLVQESLKEFFEAQPNVEFLQVAPSVEDFLKTFDAFEKLPEVLLLDINLLGMSGIDGIPLIMEQLPKLDIIMLTTFEDNDSIFKALCAGACSYLSKKTPLKKILEAVEVVYDGGSYMSPSIARKIVNHYAPQRTKLKVLTKRQQDIVCGIVDGKSYKMIADDLCVSLDTVRSHIKNIYKALEINSKAELIRKSYDNEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBC1</accession>
    <name>A0A5C6ZBC1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000041">
        <property type="protein sequence ID" value="TXD86719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046219">
        <property type="entry name" value="DUF6252"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19765">
        <property type="entry name" value="DUF6252"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022739621" evidence="1">
        <location>
            <begin position="22"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="185" mass="20294" checksum="C65C124BD636A146" modified="2019-11-13" version="1">MKKLKSMCLAILIIFPLWGLGGCNNDDDNNNNDTLPPATQIGANTVGCLVNGEVFLPRSEGINPAVVVNYEFIGGEFFFLLNFADLRGIGFKDVFLNTRAITLQTGQTYILDKNLNDDGDYSGGGGGHSLSLSNVFYTNNSLLGELTITRIDLSNSIISGNFWFDAINEAGEIVEIREGRFDYEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBG1</accession>
    <name>A0A5C6ZBG1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SdpI family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000026">
        <property type="protein sequence ID" value="TXD87345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025962">
        <property type="entry name" value="SdpI/YhfL"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13630">
        <property type="entry name" value="SdpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="113" mass="13479" checksum="F98C545F04093CF3" modified="2019-11-13" version="1">METIYKSILTLDLTLFASLLLFYFIKKDTINPILGYRTKRAMKNQKNWIFAQKFFSKNWLYSIPIILITQIPILFDNTLDNVIPISLLNFVIYSIYLIYVTEKKLKKMDDENQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBX5</accession>
    <name>A0A5C6ZBX5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000032">
        <property type="protein sequence ID" value="TXD86989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="180" mass="20828" checksum="D1D1BDB08AFA3530" modified="2019-11-13" version="1">MKKNIKAFFKEIVPIIIGILIAIYINNWNEDRKDKNYINRISASINKELTETNNDIIEKFALQETLIDTLDFYKKDDKISILDILMKVNGVSIPSIKISSWKAISNSKIELMEYDKISSLANIEEEKEILKAKSNYVMNLVYSNLNDTGIDKKEILKIMMFDIISTEITIQEEIEVIISE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBZ5</accession>
    <name>A0A5C6ZBZ5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_20295</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000064">
        <property type="protein sequence ID" value="TXD86393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="273" mass="30413" checksum="E8566F85C1FA2066" modified="2019-11-13" version="1">MKQKLFFLALTLFIISNIKLFGQELCQTPSQTNNEFLNKSALLRTSSNDNSYCLKVYFHVIRRSNGTGGQSVSAVNQAFQILNQDFNSHNISFSWDNIIDYIDNTSYYDSPGATIYSINSHQDGIDIYLFDDDTDSSGGAANGVGSSSEFYVTGSFNQPPFQSLSTSRVVSHEMGHVLFLWHTFRGTNFPQFEDGDFCPELVDGSNSDICGDYVEDTPADPNMAFNIDSSCQWLGSGTGANGDSYNPDEQNIMAYTNVCLILRIFKVYECEMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCC4</accession>
    <name>A0A5C6ZCC4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Helix-turn-helix transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_17775</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000028">
        <property type="protein sequence ID" value="TXD87164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="220"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="HTH araC/xylS-type" evidence="2">
        <location>
            <begin position="286"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="394" mass="46585" checksum="FC723F75B209298B" modified="2019-11-13" version="1">MFFDFNQKSSLLLIFFFNGIIFSFLLFKRAIAHNHNPSKWLGWFVMLSTLYISPFMFGYGGWYSKKLYREILFFIPFQQLFLLGPIIYFYTQSLLNKTFRLEKRDLIHFLPAALYMVYTIIIFVTDKLILEEYYFYADGKDKDLAFWYQIAGLLSMLSYLLLSLRYYFIYKNLAYQEVSFADAILFKWIGHFLFVFTAILVLRVLFFILNPEWWEFGSKFWYYLCFSVLFFYIALSGYFNTVRAPFALDTSLLDYPRKTNLKKEMESSKLKHSQQTEIPDLEEWKSKITKFIEQEGLYTNPNLTLTDVASSLQTNRNLISKAINQGFQMNFNDYVNAQRVDAVISKFRSGQQNSKTLLGIALDCGFNSKSTFNRAFKKKTLLTPKDFLDKKGVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCJ3</accession>
    <name>A0A5C6ZCJ3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Vanadium-dependent haloperoxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000042">
        <property type="protein sequence ID" value="TXD86715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="SMR" id="A0A5C6ZCJ3"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxi_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="SSF48317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="acidPPc" evidence="1">
        <location>
            <begin position="313"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="440" mass="50238" checksum="415139C38A11379B" modified="2019-11-13" version="1">MRFYKIMIALLLLSSCKKSEPIVITPNDYHNAVDKVVEIMVHDIFSPPVASRIFAYPNIAAYEIIAMQNPRYKSLSGQVSELTNIPKPKTPDHINFELAALIAHMDLSRQLVFSEDQMTSYSDSLYDIWEHKNPEIFRNSKAYALEVNKHIAQWMNADNYKQTRTMSKFNIDSNDIARWEPTPPSYMDGLEPHWNKIRTFVLDSASQFKPIPPPIFSMEPDSQFHKELVEVYDISNKITEEGDTSEEIQIAQFWDCNPYVTVTRGHLMFATKKITPGAHWIGITKIASKKSNMNFEDTVYAHTKTSIAIFEAFISCWDEKYRSNLVRPETLINKYVNDSWKPILQTPPFPEYPSGHSVASGAASIALNSIFGDDFQFDDDTEQRFGLPTRSFNSFEQAANEAAISRMYGGIHYRAAVEVGVKQGRDLGIFVVNNLNMLNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCY9</accession>
    <name>A0A5C6ZCY9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18615</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000032">
        <property type="protein sequence ID" value="TXD87004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="150" mass="16739" checksum="D32CBD1F44814B7D" modified="2019-11-13" version="1">MKSSKSIYQYIPKIACILFSILFIYAGTSKLLDFQNFKTQLGQSPILTAYAEYVSWGIPSIEFILAGLLLFTKQILLGLYASYALMVMFTAYIIIILNFSDYIPCSCGGVLESLGWTEHLIFNSGFVVLAILSILILKRDSLKPNTISNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCZ6</accession>
    <name>A0A5C6ZCZ6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-glucosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_16120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000021">
        <property type="protein sequence ID" value="TXD87676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019282">
        <property type="entry name" value="Glycoamylase-like_cons_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016883">
        <property type="entry name" value="UCP028431"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10091">
        <property type="entry name" value="Glycoamylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028431">
        <property type="entry name" value="UCP028431"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycoamylase-like" evidence="1">
        <location>
            <begin position="220"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="455" mass="50381" checksum="31FF7533F583144A" modified="2019-11-13" version="1">MKKISVLAILIVGLCSCSDSSKSEPFDPNAGDDGPVQVEPLSDEAILDLTQKETFKYFWDFAQSNSGAARERYIPENPSFDQNTVATGGSGFGLMAILVGIERGYVSRTEAMTRLSQILTFFENADRFHGAWPHWINGTNGSVIPFSAQDNGGDLVETAFFVQGLICVKEYFKNGSAEELALSNKADVLWKGVEWNWYTQNENALYWHWSPNNGFAIDLKLTGYNEVLITYIMAASSPDFAIDQATYAGGWATNGNIVSSNSKYGVPLILKHAGSPNFGGPLFFSHYSFLGLNPSNLSDAYGNYWDVAKNHTKINRQYCIENPNDFEDYSADCWGLTASYSRNADGSLGYTAHSPVNDTGVISPTAAISSIPYTPMESLDAMHYFYQNKAKLLGPAGFYDAFSPEYDYWVARAYLAIDQGPQIIMIENYRSGLLWNLFMQNTDVQNGLTTLGFTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD01</accession>
    <name>A0A5C6ZD01_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_16990</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000025">
        <property type="protein sequence ID" value="TXD87367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="10"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="46"/>
            <end position="53"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD87367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="264" mass="29288" checksum="3807CF4B7BFBC2C2" modified="2019-11-13" version="1">MSKDTHNSILSTENLSIGYASKKGQTVVAKNINISLEKGELIGLVGANGIGKSTLLRSLSATQAALDGSIFIKNRRVSEYSALELAKHLSLVLTEQLLSKNLSVFELIALGRQPYTNWLGTLSEADLSIVNTAIDQVHLNDLQHRKCHELSDGQLQNVMIARALAQDTELIILDEPTTHLDMYHKAYILKLLQKLTKETQKTILFSSHEIDLAIQLCDSMIVMTPNDVVYDTPCHLIEQGIFETLFPEDLIAFDALTGSFRIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD26</accession>
    <name>A0A5C6ZD26_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Bifunctional pyr operon transcriptional regulator/uracil phosphoribosyltransferase PyrR</fullName>
            <ecNumber evidence="2">2.4.2.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pyrR</name>
        <name evidence="2" type="ORF">ESY86_17155</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.9" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000025">
        <property type="protein sequence ID" value="TXD87397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004845">
        <property type="term" value="F:uracil phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="1">
        <location>
            <begin position="6"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="179" mass="20714" checksum="93131E819667411A" modified="2019-11-13" version="1">MSQKVLLNAKELNIILHRLACQLIENHNDFSETVLIGLQPRGTFLADRLAKLLQTNYKIKNLKLGYLDITFFRDDFRRGEKILEANSTVIDFVVENKNIVFIDDVLFTGRSIRAALTAIQSFGRPNEIELLTLIDRRFSRHLPIQPNYRGRQVDAINEEKVKVNWVENEGEDVVYLINS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD54</accession>
    <name>A0A5C6ZD54_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase family 4 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_16830</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000024">
        <property type="protein sequence ID" value="TXD87444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="20"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="195"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="383" mass="43909" checksum="7795066C23CDDD0B" modified="2019-11-13" version="1">MNIAFLTPEYPHPKVGHSAGLGTSIGNLSKELARQGHNIYVFVYGQKESLDFNDESVNIYLIGDKNYNFAKWFRYRKHIQKYVQTVIDIHNITILEVPDWTGISAFMRFSVPIVMRFHGSDTYFCHLEKRQQKMKNRWFEQLAVNKAEAFIAPTSFAGQLSKRLFKIQDDKPVATIHYGLQLENFINTNPSSYEAHTVLYIGTLIRKKGVFELPEILKHVKKQVPNAKLLIIGSDAPDIVSGNTSTWELLKNSFETSLLRDVHYFGKKPYHEVQEAIKTSHVCIFPSFAETLGMVTIESMALQKPVVNSSIGWAQELIIDRETGFLVHPKDHVLFAERIISLLQNKDKCLTIGKAARSLVEDRFDIRKQAVKNIQFYQDISRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD74</accession>
    <name>A0A5C6ZD74_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Response regulator transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_16475</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="2"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="124"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="124"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD87623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="224" mass="25358" checksum="EDD6FB2785FD03AD" modified="2019-11-13" version="1">MKILIIEDEPQMLENMRETLEKEHYTVESASDFKAGLNKIGAYDYDCILLDIGLPDGNGLELLIELKRQDKADGVIIVSAKNSLDDRIEGLNLGADDYLSKPFHMAELHARVKAVIRRRNFEGSNFIEIGNVIIDPESRSVSIEGQTINLNRKEYDILTYLVSNKTRLVTKTALAEHVWGDYIDQADSFDFIYSQIKNLRKKLEKASISIEAVYGVGYKLDLNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE01</accession>
    <name>A0A5C6ZE01_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lysophospholipid acyltransferase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18790</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000034">
        <property type="protein sequence ID" value="TXD86918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07986">
        <property type="entry name" value="LPLAT_ACT14924-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045746">
        <property type="entry name" value="ACT14924-like_Acyltransf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19576">
        <property type="entry name" value="Acyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PlsC" evidence="1">
        <location>
            <begin position="87"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="610" mass="70001" checksum="B284019DE58A215B" modified="2019-11-13" version="1">MTKKQDTGLVTAKEVAEVIKLDKYGVLGTLVGWSLMKALKISKINTVYNRNKHLSGTDFLDALLDEFQIKFEIPAEDFKRLPKDGAYITVSNHPLGGIDGILLLKLMAEQRADFKIIANFLLHRIAPMKPYILPVNPFEDRKDAKSSLAGFKTAIKHLRDGHPLGVFPAGEVSTYRDGKLVVDRPWEDAAMKLIQKAEVPVVPIYFHAKNSKLFYKLSKISDTFRTAKLPSEVLTQKHRTIKVRIGRPISVSDQSEYKSLAEFSEFIRKKTYMLSNSFDERGKFLGNLASNLRVPKAPKRIVTPVSSEAMGKEVDALRADDKRLLESKNYEVFLTEAEFIPNIMREIGRLREITFRAVGEGTNESIDLDHFDTYYHHMFLWDNEAKKLAGAYRMGLGSKIFAAYGIDGFYLQDLFRFEPELYKMMRESIEMGRAFITGEYQQKPMPLFLLWKGIVHTTLRYPEHNYLIGGVTISNKFTNFSKSLMIEFMKSNYYDPYVAQYVRPKKEFKVKLKDADKDFVFDETEADLMKFDRIIDELEPGPLRLPVLIKKYIKQNAKVVAFNVDPLFNNAVDGLMYIRIADLPESTVKPVMEEFQAELERKFSNGNSEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE37</accession>
    <name>A0A5C6ZE37_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">T9SS type A sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_15490</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023127650" evidence="1">
        <location>
            <begin position="23"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="domain" description="Por_Secre_tail" evidence="2">
        <location>
            <begin position="546"/>
            <end position="623"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="624" mass="66532" checksum="B00CB70B71A43AC6" modified="2019-11-13" version="1">MKKIYNVITILLVLLVTGNMNAQALSGTYTIGDNTADYETFLLAIDDLQLNGVDEGGVTFTILPGVYNERILLENISGLSETSRITFFADPGSVTIEAVGSSNGNEAIIRVNDLSYITFDGIGLVDGSTSGSELEFGYHFVGTSAAGCSNNIITNSSIFLGASGARPISATRGIFFTSSGNSLETSNSNNIIDKVTIDNTSWGIQFRCASSFLGQITQPDFNNQIIKSTFGANQSLGHDFSSGALAINALGGRDMIIKNNVIESVVNLNSAPSLPVSTSGISLDSCSGEVTENEINNLEYEGTIGAVFGIRSSTWLGDTTLIANNKISGLIRSDFTASTTDPSFTITGIWIFNQGGNNGLASILHNSIFLEAELPVSYSSAGVNLSGGSTGQFPGEVFNNIIVNNISTSSPNYRSFGLVDGNTSRGFLISDYNDLYADGDNGYLGAIGRELGGTEQFTNNLEDFISFSETNENSVNFLPEFLDASLGDLSFADDLVATTDYLVPTLPEVPLDIEGTTRRSPETFLGAYEGTEVLSIKDSNLSSIAIYPNPAREILNLSIPNMMPNEITVRIYDQIGKQVLELQGLKFDGTSSAASVPVENLQSGMYFIKINSGSSEITKKFIVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE78</accession>
    <name>A0A5C6ZE78_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">eIF2A domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_13610</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003714">
        <property type="term" value="F:transcription corepressor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016575">
        <property type="term" value="P:histone deacetylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045183">
        <property type="entry name" value="Ebi-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013979">
        <property type="entry name" value="TIF_beta_prop-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22846">
        <property type="entry name" value="PTHR22846"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08662">
        <property type="entry name" value="eIF2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="SSF50978"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="eIF2A" evidence="3">
        <location>
            <begin position="167"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="332" mass="37968" checksum="6961B6352A293BA4" modified="2019-11-13" version="1">MASNLKNPMIKIKLMLFILILSTICGCKKKESTAKIERENWWLWSANWSSNGEQIAFGGTQDTLRLFSSATNSIVENVPIQGTITKTEWHPSKNKLAISIQDGKNKSLILNLETKKRILLDRIDENGARAIGWNKNGELLAVGDYSGFLNIYNEDGELLKRINTKQKALIALHWHPKNNIIAAVGEKISVYNFENDTLFDVKPRKEEVLMLCVAWHPSGEFFVTGDYGDFEKDYPPLLQFWTSKGKNLRNIENSKAEFRNMAWSNDGELLATASEFLGLWNKKGDLIRKYDSENLLWGIDWNNSDEKIVTSDDKGKIMIWEINLDTSIELKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE99</accession>
    <name>A0A5C6ZE99_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cell surface protein SprA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">sprA</name>
        <name evidence="3" type="ORF">ESY86_14460</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026377">
        <property type="entry name" value="Cell_surface_SprA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025684">
        <property type="entry name" value="SprA_N_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14349">
        <property type="entry name" value="SprA_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04189">
        <property type="entry name" value="surface_SprA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SprA_N" evidence="2">
        <location>
            <begin position="7"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="SprA_N" evidence="2">
        <location>
            <begin position="1146"/>
            <end position="1638"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="443"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1941"/>
            <end position="1983"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="454"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1962"/>
            <end position="1983"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="2448" mass="275885" checksum="664ACEAEBDC05FC6" modified="2019-11-13" version="1">MPNPQSIISKYTYDPELDRYIYTETVGKFNINYPIILTPAEYQKLVLEEQQRNYYQQKIDAKDGKKEGTEEQQKNLLPEFYVNSGLFETIFGGNTIEVIPQGTVEMDLGILFTRQDNPTFSPRNRSNFTFDFDQRISLSLLGKVGTRLQVTANYDTESTFDFQNLVKLEYTPTEDDIVRKIEVGNVSMPLNSSLITGAQSLFGVRTELQFGKTRVTAVFSEQQSQSQSVTAQGGGTLDEFDFFALDYDENRHYFLAHYFRDTYDRSLLRYPYIENNIQITRIEVWVTNRSNETENVRNLVAFQDLGESGLDPNNPDNDNIGLVNPPTNFVNVPIGSYPDNKNNTFDPTNIGNAGSLLSSAVRDVSTVEQGILVPANEGFDFGKLENAKKLEQNRDYVLNQQLGYISLNQRLLNDEIVAVAFQYTVGGVVYQVGEFANDGVNATSTGNDTDNDGIPNDIDADVDGDGIVDNGPDSDGDGINDVGDSDVNGDGTIDNGPDQNGDGINDNYVTIQVGSTQSLVVKMLKSPITDVNQPIWDLMMKNIYDTGAYQLQREDFKLNIFYTETSPLNYITPVEGTTFPIFENNSPFDPNDDVEIQDTPLIRLFHLDRLNFNNDPQLGGDGFFDFVPGLTVLTQNGKIIFTKVEPFGRYLFDVLDDDGSQMDNGSDYQYNGDTANSPYNLNQQKYVYDVLYKQTKTAALDQAEKNKFQIKGRYKSSGSDGIPLGAFNVPRGSVVVTAGGRTLVEGVDYTVNYQIGRVNILDEALKASNTPINVSVENNAVFGQQTRRFTGINIEHQINENFVLGATLLNLNERPITQKANYNTEPINNTIYGFNGNYSSEVPFLTRLVNKLPNIDTDVPSNLSLRGEFAYLLPGAPKGTDFNNEATAYVDDFEGTQGEISLLSPQSWFLSSRPRGLGRSYPGLGEEDNVGLQNGFDRALLNWYTIDPIFYSNQRPNEINDDDVSNLYTRRIFIDEIFPQLDIVQGQTTVINSLDLTYYPTERGPYNFDPSAAVADLDPADSWAGITRAITSTDFEQANVEYIEFWLMDPFLDDTTQPTGGKLFVNLGNISEDVIKDGKKQYENGLPANGDISGLNPTSFGGVVPLNQSLIYTFDTTGQERVNQDVGYDGYADADEIAQFGPEFGPDPSNDNYLYYLNTDGDIFDRYRFYNGLEGNSPDTFTNTNRGSTAQPDVEDINRDNTMNTIDSYYQYEIDITPTSLNVNNPQINDIKSRQITLQNGQTADVTYYQFRIPISEPTLAVGGISDIRSIRFARMYMTNFTQKTTLRFATLDLVRSDWRRYRLALDDDPNNDTDNTALNVGVVGLQDNEGNYVLPPGVVLERLNNNNNIQRQNEQSLQIEVCELEPRDSRGVFKNINIDMRQYNKLRMFIHAEDGETGSLSDGDLVAFIRMGNDFTQNYYQIEVPLRVSSGFVSSESVWPEENEINLDLSVLEKIKSLGISNGSLADPIPTFYDVIGDALVEVGEFDQHTFGQQRVTVKGNPNFGDVRVLMLGLKNPGGNGMNACGEIWFNELRLSDLENEGGWAAVAAMDTNIADFATLSATGRKSTIGFGSVEQRPNERSREDVEQYDLVTNINVGQLLPKKWGIQIPFNFGVGEEMITPEYDQFYRDLTLDSRLDAADSEAERETIRTRSEDYTKRKSINFIGVRKQRTGDAIPRFYDVENFTINYSYNRVEHRDFEIERSLDQNLRAGANYNYSFAPLSIEPFKKNDSLFTGKYWKILKDFNFNPIPTNFTVNSDIIRQFSSQKFREVDLTGNNIGLAELFRRNYDFNSQYTINYNLTKALNLNFNASNSNIVRNYFVNDVLNGRQDPNLTVWDGFFDFGDPNIQSQQLQVNYEIPLYKIPTLSFLRATYSYTGDFQWQKGSDLFNSLRVPDDLNDPNSEFSTYNLGNAIQNANTHNINSTLNMETLYKHIGLVKKRKTPTRATRRSAAPKSLDDTAASARTAQNPDPEAQNTESAGQKALNSAVGLLTMVKRIQINYSENNGTFLPGYLNTPGFIGTLKPTFGYTFGSQADIRDRVARNGWLTVYPDFNQQYAETSNRILDIAADIEVIEDLKIDLFGNRTYAHNITENFVGLDTDDDGLSDAYENLITNAFGNFSISTALIKTAFGKSDENESTAFDDFRGNRLVVAQRLARTFYGNGNIPVDTEGYPLGFGKTSQAVLLPSFLSAYQGSSPDKVSLSAFRDIPIPNWQLKYTGFMKIKWFKDKFKRFSLTHGYRSSYTINQFRTNLDYTAGDPALGYDSPLNEAALDQSGDFKNRIIFSNINLEEQFNPLFRLDFEMNNSVKVLAEMRKDRIISLSFDNNLMTEIRGNEYILGLGYRVKDLRIRSKLAGPKQIIKSDLNMKADISVRNNKTIIRYLDVENNQITQGQTIWGIKYSADYAFTQNLTAIFYFDYTFSEYEISTAFPQTTIRSGFTLRYNFGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEA9</accession>
    <name>A0A5C6ZEA9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FkbM family methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_16895</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000024">
        <property type="protein sequence ID" value="TXD87456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006342">
        <property type="entry name" value="FkbM_mtfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05050">
        <property type="entry name" value="Methyltransf_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01444">
        <property type="entry name" value="fkbM_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_21" evidence="1">
        <location>
            <begin position="77"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="279" mass="32469" checksum="311E4AF8ECB82087" modified="2019-11-13" version="1">MKRKWLKILLKILVPKKYQYVFIDTVFSAFNTNPLIFAYNRIGILKWQNEKLSGEEDFILNFLIKSFPDRKDTVFFDVGANKGQYSSLLSKFYKNVSIYSFEPLKASFAVAEKNLSKFENITVNNFAFGSQEKKLSIFFDSTDDTSVKASINRSVISDIHKNQKISNELIDIRTIDDYCSKNGIVKIDFLKIDTEGYELEVLKGAAKLIENNGIQTIQFEFNEMNVISRVFLKDFYDILEPYGFNFYRLNEKGMINLKSYNPIHEIFKFQNIIATKLNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEK6</accession>
    <name>A0A5C6ZEK6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">VWA domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_13175</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="312"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="93"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="347" mass="39239" checksum="EA23EC694D66B16F" modified="2019-11-13" version="1">MFQFQLEEKIWFWTLLIIPLLLLLFGMLQFWKYRAQKRFANKALLKRLSPNQSVFKSVLKVIVLSLAFGCLTLALVNPKVGTKLETVKREGVDIVFAVDVSKSMLAEDIAPNRLEKSKQLVTQIINSLTSDRVGIIAYAGTAFPQLPITTDYGSAKMFLQNMNTDMLSSQGTAINQAINLSKTYFDDDQKTNRVLIIISDGEDHTDEATNAAEAAEKEGISIYTIGVGQAKGGRIPLKQNGKIIGYKKDNKGETVITRLDEENLKRIAAEANGVYLNGNDTSEVIDNIKDILNQMDKTEFEAKQFADFESQFQWFLGLGLFFLFLDIFFLERKTAWLKRLNLFNEDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEP2</accession>
    <name>A0A5C6ZEP2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ligase-associated DNA damage response exonuclease</fullName>
            <ecNumber evidence="2">3.1.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000021">
        <property type="protein sequence ID" value="TXD87659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026360">
        <property type="entry name" value="Xnuc_lig_assoc"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04122">
        <property type="entry name" value="Xnuc_lig_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="321"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="340" mass="38295" checksum="9659B2CC9F82354E" modified="2019-11-13" version="1">MKLIKFTKKGIYCIPGKFYLDPWFPVDFAIISHGHADHARWGMSHYLCHDDSKAILKHRIGQDISVESMPYNSEKTINGVKVGFFPAGHTIGSAQIRLEHKGFVVVFSGDYKVKNDYLTVPFEPVKCHEFITESTFGLPIYNWMKEEELQQKMQDWVLNNQARNRTSVFLGYSLGKAQRLMKLMEGMGEIYVHTAIHNINEAIATTGIKLPATKKWTAETDKKEVQNKIVIVPPALLGSNMIKRIPNAATAICSGWMQIRGNKRWQSVDAGFPVSDHADWNGLLQAVKATEAEKVYVTHGSQAIFSKYLNEIGIPSEEVKTEYGSNEDDTEAEPKSKQAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEP4</accession>
    <name>A0A5C6ZEP4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HAMP domain-containing histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_16470</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="221"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="422" mass="49007" checksum="E9C23C2C7910AAEB" modified="2019-11-13" version="1">MKLLNHTSKYLLFLLLPILTVWAFLFYYAMLDEIYDSLDDGLENQKIILMQQMLRDASILEHANFDEHIYSFSRISKSTHENFEESYRDTLMFMHNEKEFEPVRIFETAIKHDDEAYYKLKIITSMVEEDDLIESLVYYLLGLYALLVLTILVMNNLILRKIWKPFYTLIGQLGKFRIEKNTFVDIPSSNIEEFSLLNTTISQLINKARSSYTDQKQFIENASHELQTPLAISINKLELFLEHQNLSQEQSKDIVTVLDNLGRLTRMNKSLLLLSKIENKQFEEATKVNFNTLTETIISDFEDFAKHRKVHISIDAKAEIFYQINQDLATILLSNLIKNALIHGNKNEHVLIAIEPNTWSISNKGEQMPLDDTVIFSRFKKASTSKKSTGLGLAISKAIADKYTLNLSYTFTDAHSFTLKFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZER2</accession>
    <name>A0A5C6ZER2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TolC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_13415</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022849417" evidence="3">
        <location>
            <begin position="20"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="373"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="471" mass="52605" checksum="A8A10257B345AC50" modified="2019-11-13" version="1">MRLKLFVVLFFSSTVLIFAQTDTRLPLSLEACISLAIEHNLELKSSELAKQSRAINFNQSKNALLPNINGNYNIGLSNGRSIDPFTNDITNQELIFSNAGLGLDATIFNGFRLINSWKQAKLNLEAAEMDVEAAKQLLVLNVTLTYLQVLNAQDLVRLAQSRLQTTQGQLDRLKSLYEEETGNPAEYRDLQGQIAMDAANIAETKNTLETELINLNTLVNAEEAITVAPLNMEMDFETYLFSAEAVYQKALEVFPSVKASDLSLAAAEKAVSVAKSQYIPEISLFANLNTNFSSAARLFNDLGTSIVETGNFVNIDNQAYSVFTEQTSFLSSEIPYRDQFDNNLNSLVGVAVSIPIFNGFRAKNNVALEKIKKAEARTALEQTKLDLKQAVNQSYNAMQTAFQRYDLLQDQVEAYEESFRINEIRFNNGVSNSVAYIISKNNLDTAQINLSNVKYEYALRVKVLAYYQNKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZER8</accession>
    <name>A0A5C6ZER8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ligase-associated DNA damage response endonuclease PdeM</fullName>
            <ecNumber evidence="2">3.1.-.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pdeM</name>
        <name evidence="2" type="ORF">ESY86_15975</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000021">
        <property type="protein sequence ID" value="TXD87657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026336">
        <property type="entry name" value="P_estr_lig_assc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024173">
        <property type="entry name" value="Pesterase_MJ0037"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000887">
        <property type="entry name" value="Pesterase_MJ0037"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04123">
        <property type="entry name" value="P_estr_lig_assc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="1">
        <location>
            <begin position="31"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="214" mass="24718" checksum="F667CFBC12039D4F" modified="2019-11-13" version="1">MNLVEEQITIEGEVLALTSLRAMYWEKEQALVASDLHIGKSAHFRRHGIPISAKVQQKDLQRLEFLVSHYQAKKLIVVGDLFHAEVNTDMADFKHWRNQNLDLEIILIKGNHDRLKDDIYEAYQISCCQKELLMPPFQFIHEPKASRQFSISGHLHPGVRIKQKGRPQIKLPCYEVSATQLILPAFSEFTGLAMSRAKKGKQFYAFTETSFFEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEX6</accession>
    <name>A0A5C6ZEX6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_15585</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="137" mass="15213" checksum="299C7C8C6D426A14" modified="2019-11-13" version="1">MKIDALGAVEWKSAFGGISYEVAYSIKQTSDGGYIVAGLTASLGGDVTENFGYEDIWVLKLDTSGNLQWQKSFGDGEIQKAWEVQQTLDGGHIVTGYTYIGIIHSDYTVLKLDTNGDLEWQNNYQYGWEYCSFGARI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEX9</accession>
    <name>A0A5C6ZEX9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4136 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025411">
        <property type="entry name" value="DUF4136"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13590">
        <property type="entry name" value="DUF4136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4136" evidence="1">
        <location>
            <begin position="21"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="173" mass="19175" checksum="EED8BFA73CBC834B" modified="2019-11-13" version="1">MKNSPLVLVFLIMTSCAPIRVYYDYERGRDFTQYKTYNYYKEMKTGLSELDSERLLNAMDAALQSRGFSKSDTPDFFIDINSNSYRETDGNNVGVGLGGGGGNLGGGVSLGFPIGLNNLNREIVVDFVDENKNGLFWQAITGSSYRPNASPEKREAQFKAIVAKVLEGFPPEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF08</accession>
    <name>A0A5C6ZF08_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_15770</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="246" mass="28755" checksum="F2908B486911FF40" modified="2019-11-13" version="1">MMEQQVYKFCILILVFVTMFFGCKSNNNGQILSIDKPQMRQPKDKNAFSVIAFRPLFEGVINKEKYESYCLDVVKNTTEPPFFKSFVYDDLYIDIVAPTFHKNYIGPDSNDGSRNIVRIMQSENVMNIVLDDSFIGDYHIYIDSLTFKEGSFYFDLANKKFRKISLEGKLKTLEKWKSSEGLLNEECINKIPLYKVIDSISDKNLIQDMLSLDFIKVSQDDLVTYDVLYNRREKERIRKARSKNKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF30</accession>
    <name>A0A5C6ZF30_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_11805</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="129" mass="15350" checksum="1F52A4CF0F0EE1DF" modified="2019-11-13" version="1">MHKFLIFLLPLLFLNCYQVERNCADFKTGTFEFKYMLDGVEKTGTFTRTEDLNIDFYENRIDSASVRWINDCEFIQKKLNPKNQAEERAIHMKIISTSEDHYTFEYQLAVKMPYKKQRVEKGTATKLND</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF66</accession>
    <name>A0A5C6ZF66_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Formimidoylglutamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the arginase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016813">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006035">
        <property type="entry name" value="Ureohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11358">
        <property type="entry name" value="PTHR11358"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00491">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="SSF52768"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51409">
        <property type="entry name" value="ARGINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="340" mass="37874" checksum="B4855DCC72BD29BC" modified="2019-11-13" version="1">MKYLKRLTHSELSKILNPRPKEIKFGEQIVLLSNSTPIYDQLLNLDVGYVIFGIKEAVGVFANCGNHGTENAWDAAIKVLVNTQANPHTHANKVLILGCLEFEAFQEKINTLDQSNKKDLKKARKIVQKIDAEVTFLMHQIVSAGKIPIVIGGGHNNAYGNIKGTSLALKKPINVINFDAHHDFRDEEGRHSGNGFSYAFAEGFLKRYFIFGMHENYVSDTILNTLKKLKNIQYNTFEAIAIRKTLDLKHEMNAALEHLGDAAFGLEIDCDAIKNTPSSAKTPSGFSAEQARQFVDFFGSCENASYLHICEAAPTKETETQVGKLITYLISDFIRAHAND</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF68</accession>
    <name>A0A5C6ZF68_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histone deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_15355</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the histone deacetylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004407">
        <property type="term" value="F:histone deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016575">
        <property type="term" value="P:histone deacetylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09993">
        <property type="entry name" value="HDAC_classIV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.800.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044150">
        <property type="entry name" value="HDAC_classIV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000286">
        <property type="entry name" value="His_deacetylse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023801">
        <property type="entry name" value="His_deacetylse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037138">
        <property type="entry name" value="His_deacetylse_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00850">
        <property type="entry name" value="Hist_deacetyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01270">
        <property type="entry name" value="HDASUPER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="SSF52768"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hist_deacetyl" evidence="2">
        <location>
            <begin position="43"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="300" mass="33660" checksum="C216C279F97C6D7B" modified="2019-11-13" version="1">MLKIAFHPIYKHSLPEGHRFPMLKYELLPEQLVYEGTCTEANFFEPEIPDDSHILRVHTEAYYQDLNQLTLDKRAARKLGFPLSADLVKREIIIADGTMKASEFALKNGIAMNIAGGTHHAYSDHGEAFCLLNDQAIGARYLQHKKLAEKILIVDLDVHQGNGTAEIFANDPSVFTFSMHGKGNYPFKKEVSDLDIALENDADDATYLKLLYETLPKLIKTERPDFIYYLCGVDVVASDKLGRLGLSLEGCKERDRFVLQSCKDAKIPVMCSMGGGYSPDIKIILEAHANTFRVAQDLFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFH4</accession>
    <name>A0A5C6ZFH4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Acylneuraminate cytidylyltransferase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_16840</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000024">
        <property type="protein sequence ID" value="TXD87445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003329">
        <property type="entry name" value="Cytidylyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02348">
        <property type="entry name" value="CTP_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="237" mass="26435" checksum="3B764977263EAB1B" modified="2019-11-13" version="1">MRILAVIPARGGSKGVPGKNIKLLGGKPLVAYSIEKANQSKLLDLVILSTETKKIAAIGKKFGANVPFLRPLELAQDDTPTIDVLKHAIDFYESQTIFFDAICILQPTTPFRECGFIDKAIAKFIETAVDTLISVLPVPHHFNPHWVFELNGQNFLKIATGDDKIIPRRQELPQSFYRDGSIYLIKTEIIKNQNSLFGATIGHIQSSEESYVNIDMMQDWENAEKLLANKLNNIGDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFK1</accession>
    <name>A0A5C6ZFK1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase family 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="5"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="330" mass="37901" checksum="599A3B958B044CD0" modified="2019-11-13" version="1">MKIAIVILNWNGRKLLENFLASVVAHASGAAVYVADNASTDTSIQFIKTSFPKVKIIQNSTNGGYAKGYNDALKQVDAEVFCLLNSDVEVTAGWLDSIYTEFETHPETAIVQPKILDYKKKDHFEYAGAAGGFLDRYGFAFCRGRIFESIEKDEGQYNDRSSIFWASGACFFIRKSTFDALNGFDEHYFAHFEEIDLCWRAFNKGFDCVYIGQSTVYHVGGATLEPANPKKTYLNFRNSLYTITKNTGYFLPGILFSRMLLDGIAGLRFLLQLKFDHFWAILRAHFTFYSNLPRLLKQRRMLPQKKNHELIQSIVWAYFINKKRRFKFLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFP5</accession>
    <name>A0A5C6ZFP5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">C-type cytochrome</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_14350</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029467">
        <property type="entry name" value="Cyt_c7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036280">
        <property type="entry name" value="Multihaem_cyt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039118">
        <property type="entry name" value="QrcA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39425">
        <property type="entry name" value="PTHR39425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14522">
        <property type="entry name" value="Cytochrome_C7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48695">
        <property type="entry name" value="SSF48695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023027438" evidence="6">
        <location>
            <begin position="31"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="157"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="211"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="7">
        <location>
            <begin position="33"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD88065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="435" mass="48926" checksum="5B57429D0F9E1DCD" modified="2019-11-13" version="1">MIQVIYRKLASKFLNLGLIILLTFSTSLYAQDGDPEKGKSLYNTNCAACHQLDRKMTGPALRNVASRLQEEQGLGRDWLYKWIRNSSGLIKSGDDYANQIYEEYNGVAMTAYPQFSDSDIDDILAYTAQPKEEKTADVDGEVATTGTTEGGGTSNRLILGALALLFALLAISLVLVRKTLNRFADAKGLTVEAAEKKKGFPIWKAFVQNQFLVLVSVIILLLTSAYFVYGFFMQIGIDQGYEPIQPIHYSHRIHAGENAIDCKYCHSSARVSKHSGIPSLNVCMNCHKSIYQVAEETQQMGIEEYGVDYNAEIQKLYKAVGWDEEDQSYTGETQPVKWIRIHNLPDFAYFNHSQHVAVGGIQCQECHGPVQEMEIMYQYSPLTMGWCINCHRETEVKTEGNEYYTKIHEELSKKYGVDKLTVAQMGGLECGKCHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFQ1</accession>
    <name>A0A5C6ZFQ1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thioredoxin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_14305</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005746">
        <property type="entry name" value="Thioredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000077">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="98" mass="11086" checksum="72EAC6567BC11B8A" modified="2019-11-13" version="1">MSKFGELIDVDIPVLLDFFTEWNEQSTAMHPVMRDVAAALGDKAKVIKIDVDKNKELAEALRVKGLPTLIIYKNGEMKWRHSGEQDANTLIAIVQEYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFW1</accession>
    <name>A0A5C6ZFW1_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Superoxide dismutase [Cu-Zn]</fullName>
            <ecNumber evidence="4">1.15.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_11140</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>2 H(+) + 2 superoxide = H2O2 + O2</text>
            <dbReference type="Rhea" id="RHEA:20696"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:18421"/>
            <dbReference type="EC" id="1.15.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Cu cation</name>
            <dbReference type="ChEBI" id="CHEBI:23378"/>
        </cofactor>
        <text evidence="4">Binds 1 copper ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="4">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the Cu-Zn superoxide dismutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.15.1.1" evidence="4"/>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004784">
        <property type="term" value="F:superoxide dismutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00305">
        <property type="entry name" value="Cu-Zn_Superoxide_Dismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036423">
        <property type="entry name" value="SOD-like_Cu/Zn_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024134">
        <property type="entry name" value="SOD_Cu/Zn_/chaperone"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018152">
        <property type="entry name" value="SOD_Cu/Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001424">
        <property type="entry name" value="SOD_Cu_Zn_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10003">
        <property type="entry name" value="PTHR10003"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00080">
        <property type="entry name" value="Sod_Cu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49329">
        <property type="entry name" value="SSF49329"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00332">
        <property type="entry name" value="SOD_CU_ZN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0186">Copper</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Sod_Cu" evidence="6">
        <location>
            <begin position="66"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="24"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD88786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="200" mass="21301" checksum="E16F0BECC3AC2BFF" modified="2019-11-13" version="1">MKHLKLYAAALTLTLVFACKTDKEKNEMDDASTTTETDMEDGMMDDDANAMKDIRFALVPKSNSKVTGEVVFTEDEGHVTMTATLQGLSEGSHAIHIHENADCSAEDGSSAGGHWNPTAQPHGKWGDAAGYHKGDIGNFIADADGNAKVIKTTNEWCLGCDDKNKDVLSKSIIVHEGQDDFVSQPSGDAGGRVSCGGIIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFY2</accession>
    <name>A0A5C6ZFY2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">T9SS type B sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_16690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000023">
        <property type="protein sequence ID" value="TXD87541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026341">
        <property type="entry name" value="Bac_Flav_CTERM"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04131">
        <property type="entry name" value="Bac_Flav_CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022718779" evidence="1">
        <location>
            <begin position="20"/>
            <end position="1607"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1607" mass="175867" checksum="740FCA3A3175BC82" modified="2019-11-13" version="1">MRDSVLFLILLGSCYLVFAQQITTDASIPLEALIQQNLGQGCVEITNISSTVNGQASGIDSYGSFNRASSDFPFQSGIILSTGTISSAGNVLNTNPLNEGDDNWGTDPDLETALGISDVMNATSVEFDFTTAANQIEFNYLLASEEYLDANPCSYSDGFAFLIRPVGSSQPYTNIALIPGTNIPVNTNTIHNEIVEFCPASNPEYFAGYNLGDTNYNGRTTILAATAAVQPNVKYRIKLVIADQGDKFYDSAVFIESNSFQPSADLGPDIVTCANFYQLNADIENSLATYEWFLNGMPIAGETNPSLQANASGNYQVQISIQLNETSCVIQDSVLVTLNSEASLAPISDYILCDDSSNNAIESFELDSKDAEVLNALTPSTYLLTYHLSQQDAENNLNPLPSPYQNTASPQTIYVRSIDALNGCIVFTSFNLVVNPLPEANPPTAITVCDDGLPDGITQIDLSNTNDQLTGGDPNLFVSYHYTLQDAKSGQNPLYSPYTNINPNETLYIRVFDATTGCSNTTSVEISVQDSPIVNPESTAHINACEQDGDGTEAFDLSSIIGEILQGLTGVTVSFHAQLAEAQTGNNPIANANNYQNVVAGLQTVYIRIVDDTTGCFVILPLELHADITITGFSTIPFYLCDDASEDGIENFDLNQVELYLTNGYETYGILFYESEEDLNAGSNPLNKELPYSVSNSKTLYVTVIDDECETSTTIVLDVVPPINIQGLADVNYCDNDTDGFTSIALDSFNTQVAAGVNGASVSYYLTEMDAIAQDNELPPFYYNLENPQQVWVRVESSLSNCFDIAPLTINVLNSPVANTPSNLIVCDDDQDGIYTIDLESKIPEITTDTTGIAFSFHTDYDEALSASNAIDTPENYDSISQFIYVRVEDETTSCFSVVSFYADINTLPVFEAIADFENCEADGNAIADFFFYLKDQDILNDQTGKQVLYFETAQDAIDRVDIIDKYVAYQNLSSPQTIHVRVESITDEGCFGTSSFVVLVGALPIFNAPTSVFLCDDISNDAVETYDLSQKVDEIIAGSPQDLDVSFHESQYDAQNNLNPVPLNYTNSTNPQAIYARIDDGTYCRAVATFEISIIQVPSVGTPSDLRQCDTDYDGLVPFDISVVEIEILDVRQDNIVVTYHESFEGAETDAEIISDPENYTNTSNPQTVYIKINNTISNCYVTLPINLSVNLPPALNDFQSYVICENETNSFDLSTINSVVSETTSGMTFSYFLSEEDAEANENAINTDYTYNSTNDTLFIRIANNSTGCWTTYDFDLIINPLPIANQPDALEACDDDFDGFFDFDFESQTTFILGSQNANNFELSFYTSAENAFQGSNALPENYESASGQTIYVRVQNMDTGCFSSTQFQTIVFLKPQVAIPDQVICLENLPLLVSANTNNPDDTYLWSTNQSSPEIEIDEIGSYAVTVTSIFGCAITSVFEVTESEAATIEITETVDFSDPNNITITISGIGNYLYQLDANVPQESNVFENVSLGYHTITVIDLNGCSEVSKEVVVIDTPKFVTPNGDGYFDTWHITGVETLTGTIVYIFDRYGKLLKTLTYNGPGWNGTYNGNLMPATDYWFVAKVRKGDIAFEVKGHFALRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGA2</accession>
    <name>A0A5C6ZGA2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AMP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12095</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="60"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="358" mass="40005" checksum="90DFF39E87717193" modified="2019-11-13" version="1">MTPTYDKVHLKFKLNGIKYDHEQLKEVAYSLVKEGEAYEKNMGDFLLDWLDANPFVKVKTSGSTGIPKDVVIQKDAMIESALMTGDFFNISPGDTALHCLPSRYIAGKMMLVRAMILGLELDVVAPSSNPAYDDEKRYDFCAMIPLQLKNSLNRLKCIKILIVGGASVSKAIITELVKVEARVFETYGMTETVSHIAVKALNGSSGAAPDFQVLRDIQISKDDRNCLVINAAKIADNQIVTNDIVELIAEDRFKIIGRYDNMINSGGVKVFPELVEEKLQEKIEKRFFIASEPDADLGDKVILILEGTSNALEDSVFADLEKFEVPKKIYNLPKFIETETKKIQRQKTYEAILGPMTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGG3</accession>
    <name>A0A5C6ZGG3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">SDR family oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_12720</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="254" mass="27694" checksum="B7AEB5372BD8A33A" modified="2019-11-13" version="1">MERFKDKVVIITGGSGSIGFNTAQKLASEGAKIHLVDIDEDALKSKVKEAKKKDYSMSYSVADVTKSKDVETYVKDCIKQHKKIDLFFNNAGIEGVVKPIPDYPEEEFDKVMAVNVKGVYLGMKYVMPKIEDGGSIVISSSVAGLQGTAGMVGYITSKHAIIGIMRTAALELGERKVRVNTVNPGVVDSRMMRSLEDGLNPGHGDDVKEAFEKQIPLGRYAKVDDISNMVCFLFSEDSAYCNGSVYQVDGGMRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGJ1</accession>
    <name>A0A5C6ZGJ1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MotA/TolQ/ExbB proton channel family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_15670</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the exbB/tolQ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002898">
        <property type="entry name" value="MotA_ExbB_proton_chnl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01618">
        <property type="entry name" value="MotA_ExbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="133"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="177"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="MotA_ExbB" evidence="8">
        <location>
            <begin position="92"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD87793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="228" mass="24735" checksum="845BD2DD78434BA3" modified="2019-11-13" version="1">MSLLQDTAEVLLEEQPVEKTLSIIELITSGGTAGIIIMILLFVLLIAAIYIYFERLFAIKAASKIDGNFMNQIKDHVSNGKIDSAQMLCAQQNSPVSRLINKGITRIGKPLEDINTAIENAGRLEVYSLEKNVSVLATISGVAPMIGFLGTVIGMILSIFEIANSGGQIDIKQLSDGLYTAMTTTVGGLIVGIVAYMAYNHLVVKTDKVIYQMEANSLEFLDHLNEPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGK8</accession>
    <name>A0A5C6ZGK8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase</fullName>
            <ecNumber evidence="10">2.4.1.227</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10 13" type="primary">murG</name>
        <name evidence="13" type="ORF">ESY86_09390</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UDP-N-acetyl-alpha-D-glucosamine = di-trans-octa-cis-undecaprenyl diphospho-[N-acetyl-alpha-D-glucosaminyl-(1-&gt;4)]-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + H(+) + UDP</text>
            <dbReference type="Rhea" id="RHEA:31227"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:61387"/>
            <dbReference type="ChEBI" id="CHEBI:61388"/>
            <dbReference type="EC" id="2.4.1.227"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="10">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Peripheral membrane protein</topology>
            <orientation evidence="10">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the glycosyltransferase 28 family. MurG subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.227" evidence="10"/>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051991">
        <property type="term" value="F:UDP-N-acetyl-D-glucosamine:N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine-diphosphoundecaprenol 4-beta-N-acetylglucosaminlytransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050511">
        <property type="term" value="F:undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030259">
        <property type="term" value="P:lipid glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00033">
        <property type="entry name" value="MurG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006009">
        <property type="entry name" value="GlcNAc_MurG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007235">
        <property type="entry name" value="Glyco_trans_28_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004276">
        <property type="entry name" value="GlycoTrans_28_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04101">
        <property type="entry name" value="Glyco_tran_28_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03033">
        <property type="entry name" value="Glyco_transf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01133">
        <property type="entry name" value="murG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 10" id="KW-0132">Cell division</keyword>
    <keyword evidence="1 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 10" id="KW-0133">Cell shape</keyword>
    <keyword evidence="9 10" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3 10 13" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_transf_28" evidence="11">
        <location>
            <begin position="9"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_tran_28_C" evidence="12">
        <location>
            <begin position="197"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-N-acetyl-alpha-D-glucosamine binding" evidence="10">
        <location>
            <begin position="16"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="299"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TXD89247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="380" mass="42105" checksum="B8BE3B86169FC12A" modified="2019-11-13" version="1">MSKQHPYRIILSGGGTGGHIYPAIAIADELKSRFPNAKFLFVGAKDRMEMEKVPQAGYEIEGLWISGIQRKLTLRNLAFPFKLISSLWRSRQIIKAFKPDVAIGTGGFASGPLLQMATAKKVPSLIQEQNSFPGITNKLLGKKVDKICVAYEGLERFFPKEKLVLTGNPIRKDLLDLAEKTADAKDAFTLKPNKQILLVLGGSLGSRRINQLIENELVFLETNNIQMIWQCGKLYYEEYKKHNALEHVEVFPFLNRMDLAYAAADVIISRAGASSVSELCVVGKPVIFIPSPNVAEDHQSKNAMAIASKDAAIMIKESELDANFKAQFSEVIASSERRQHLSKNIKKLALANATNDIADVVEKLLGNHLPSSQTEETNRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGX3</accession>
    <name>A0A5C6ZGX3_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 11">Cytidine deaminase</fullName>
            <ecNumber evidence="6 11">3.5.4.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">Cytidine aminohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">cdd</name>
        <name evidence="13" type="ORF">ESY86_12605</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 11">This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 11">
            <text>2'-deoxycytidine + H(+) + H2O = 2'-deoxyuridine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:13433"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15698"/>
            <dbReference type="ChEBI" id="CHEBI:16450"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>cytidine + H(+) + H2O = NH4(+) + uridine</text>
            <dbReference type="Rhea" id="RHEA:16069"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16704"/>
            <dbReference type="ChEBI" id="CHEBI:17562"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5 11">Belongs to the cytidine and deoxycytidylate deaminase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.5" evidence="6 11"/>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004126">
        <property type="term" value="F:cytidine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047844">
        <property type="term" value="F:deoxycytidine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016192">
        <property type="entry name" value="APOBEC/CMP_deaminase_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006262">
        <property type="entry name" value="Cyt_deam_tetra"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01354">
        <property type="entry name" value="cyt_deam_tetra"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00903">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="12">
        <location>
            <begin position="21"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00003949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00018266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU364006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TXD88574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="160" mass="17383" checksum="8A79EE51CE48A929" modified="2019-11-13" version="1">MKDIKIETTLTVFETINELPDDMAALMQKAIDIRLKAYAPYSNFLVGAALLLDNGKVITGNNQENASYPSGLCAERTAIYYAGSQFPDAKIVKMALSAGPKAKGTAVPIPPCGACRQAISEYEVKQELPIDIYFMGTTGKVVRSKSLENLLPLGFDRSFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGZ6</accession>
    <name>A0A5C6ZGZ6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">S9 family peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_10610</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002470">
        <property type="entry name" value="Peptidase_S9A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00862">
        <property type="entry name" value="PROLIGOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022719721" evidence="2">
        <location>
            <begin position="23"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9" evidence="3">
        <location>
            <begin position="543"/>
            <end position="757"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="759" mass="86044" checksum="E07FE862E1835E80" modified="2019-11-13" version="1">MKNKILGLVTLFLISAFNISEAQDIQGSFKGILDVQGNELPITLNISKSNDDLSTTIDSPAQGAIGIPTDATTWEDNVLTVTASQLGLKYVATLNDQTLTGTFYQGGAELPLILEKFDKKIPGDTSLPTSDEELEALANWDTTSYKYEVKDFFAKPKARSFSFSPDGKFLSYREKDENGKNHIYVKNLATNAISRAIEEKEELIRAYGWANNERLFFVMDKGGNENYHLFAVDLDGSSLKELTPFDGVRVEPLEELKDDKNHMIISMNKNNPQIFEPFKININTGEITQLFKNEDPANPIMNYAFDKDGNLRGYVKLRNGVNTDYYYTLDGKTYDKFKELSWKDTFSPVSFNYTTENPDDAYVISNLESDKSQIILYDFKADKVIETLFKNENYDASGLSLSRNRNYELDYFSYEGEKEIIVPVSDYYKKLHAKITSKFPNYNYSIADVTDDESKYLILIQSDKLYGTYYSYDAINDSFELLYDLMPQLKEKDMAEMRPISFKSRDGKTINGYITLPKAAIDGQQVPLIVNPHGGPQGVRDSWGFNPETQLFASRGYATLQVNFRISGGYGKEFLESGFKQIGRKAMDDVEDGVEYVIEQGWVDKDKVAIYGGSHGGYAVLRGMTKTPDLYSCGVDYVGVSNLFTFMNTVPAYWKPMLPILKDIWYDESIPEEKAIMTEVSPVFNIDKLKKPLLVIQGANDPRVNIDESDQIVRALRAKGFDVPYMVKYDEGHGFGKEENQLQLYRTMMGFFAKHLSSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH06</accession>
    <name>A0A5C6ZH06_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ketoacyl-ACP synthase III</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_12515</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013751">
        <property type="entry name" value="ACP_syn_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013747">
        <property type="entry name" value="ACP_syn_III_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08545">
        <property type="entry name" value="ACP_syn_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08541">
        <property type="entry name" value="ACP_syn_III_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACP_syn_III" evidence="2">
        <location>
            <begin position="129"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="ACP_syn_III_C" evidence="1">
        <location>
            <begin position="253"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="352" mass="38922" checksum="99EE9AE2ECFDA26E" modified="2019-11-13" version="1">MSVRIIGTGSYIPSCIEKNENFYNHEFLNTDGSAILGTNEDIVAKFKAITGIEERRYINQELVNSDIAFYAAEKAIEDANIDKETLDYIIVAHNYGDVKFGSEQSDTVPSLASRVKHFLGIKNPKCVGYDLLFGCPGWIEAVIHAKAFINAGIAKRCLVIGSETLSRVVDKHDRDSMIYSDGAGAVVIEESNEDGGIIAHETATFAADEAHFIYFGKTNHPEITDQRRYIKMYGRKIYEFALKNVPLALKNCLEASGFGISDVKKILIHQANEKMDEAIVKRFYKLHSMETPKGVMPMTINILGNSSVATIPTLLDFILKGKLEGQEINKGDVILFASVGAGMNINAIVYQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH68</accession>
    <name>A0A5C6ZH68_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="173" mass="19972" checksum="95854F36B3A61107" modified="2019-11-13" version="1">MENDILALLFYCVPAAITGAVAYYFFKEHVSNEDKRRDYLIKKDLQKEALPLRLQAYERISLFLERIKPSQLLLRVSPNSNDKADYETLLIANIEQEFEHNLSQQIYVTDKCWNITATAKNATIQMIRKATMSDNVDSADKVREVILTELMDKRSPSDAALSFIKEEVTSMWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHG9</accession>
    <name>A0A5C6ZHG9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sterol desaturase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_12120</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006694">
        <property type="entry name" value="Fatty_acid_hydroxylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04116">
        <property type="entry name" value="FA_hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="74"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="137"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid hydroxylase" evidence="3">
        <location>
            <begin position="84"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="294"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="318" mass="37346" checksum="B5F9BD886CA22927" modified="2019-11-13" version="1">MPEFPDIILFAIPFFIISMMLELYVTTKENIQTYEKKDAFSSIAMGIGNVVLGFLSKALVLLAFMFIYTNFRVFTIPFAWWSLMLLFLADDFSYYWFHRISHECRLFWASHIVHHSSQKYNLSTALRQTWSGGFYSFVFWLWLPLIGFHPGMILLQMAISLLYQFWIHTEAIDKMPKWFEAVFNTPSHHRVHHGSNPLYLDRNHAGILIIWDKLFGTFQAELKAEKVIYGLTSNINTYNPLKIAFHEWISMSKDSFTGKKSFKNRLKYLLKPPGWKHDGTGKLSDDLRKEWREKGDRSQAQCSVGSKKADRLQKHSQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHK7</accession>
    <name>A0A5C6ZHK7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_09330</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025966">
        <property type="entry name" value="OppC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12911">
        <property type="entry name" value="OppC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="165"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="198"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="226"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="276"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="333"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="163"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD89238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="364" mass="40295" checksum="6298E4A41EB16350" modified="2019-11-13" version="1">MANTSSSLSQLALQKFKKNFWGVLSFWLIVAIGGISIFAYVLAPDDSQFANQMHLAIHSERPGFKVTMLKIPSEMNANQDWFSKVFFGIKTADTEVPISKYSIQENQLVYTEYAADGLQGSEKSLDLQVFPKQDYEKYISEKTFLFGTDKYGRDLLSRVLIGSRISFFIGFVAVFISLVIGIFMGSLAGYFGGKIDAIIMWIINVTWSIPTLLLVIAITLALGKGFWQVFIAVGLTMWVEVARVVRGQIISAKEMQYVTAARALGYDNYRIITKHILPNIMAPIIVISAANFAAAILIESGLSFLGIGAQPPMASWGAMIKDHYNYIILGKPYLALIPGFCIMLLVMAFMLIGNALRDALDVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHL0</accession>
    <name>A0A5C6ZHL0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peptide MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_09290</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Membrane</location>
            <topology evidence="1 4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the major facilitator superfamily. Proton-dependent oligopeptide transporter (POT/PTR) (TC 2.A.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904680">
        <property type="term" value="F:peptide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006857">
        <property type="term" value="P:oligopeptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17346">
        <property type="entry name" value="MFS_DtpA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005279">
        <property type="entry name" value="Dipep/tripep_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000109">
        <property type="entry name" value="POT_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018456">
        <property type="entry name" value="PTR2_symporter_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11654">
        <property type="entry name" value="PTHR11654"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00854">
        <property type="entry name" value="PTR2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00924">
        <property type="entry name" value="yjdL_sub1_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01022">
        <property type="entry name" value="PTR2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01023">
        <property type="entry name" value="PTR2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="94"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="117"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="156"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="185"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="238"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="285"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="319"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="352"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="386"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="559"/>
            <end position="577"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD89231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="609" mass="67652" checksum="4709990B1C8B68F1" modified="2019-11-13" version="1">MSTAVKPIQRKELFGHPVGLFILFFTEMWERFSYYGMRGILVLYIVASATAIDPGLGWSNKDALWLYGWYTMLVYVASIPGGWIADKFLGQKKTVMLGGLLLCCGHGILAIPQDWAFFTGLILIILGVGGLKPNISTMVGGLYQDGDIRRDSGFTIFYIGINVGAFLASISVGLVAYYYGWHYGFGLAGIGMLFGQIVFIWGQKFLKGIGEYTGGESASEAEKAASKRPLNKVEKDRVIVLLISFLIVVVFWGAFEQAGGLMNLYTDAKVDRTTGLSWMEEIPAAVFQSLNAGYIIIFGTIVGGFWIWWKKSGRESSSLFKMAVGTIIMGLGYVFMMFASQEASAEVFGKAAMYWIFLAYLFHTIGELCTSPVALSFITKLAPLKYASIMMGVYFAATGFGNLLAGKIGESAQLESFSGTMVVSKEEVMPYLSKTDIEIKNEQNKVVEINDFPINQDKNFEIRATVYPENGKVMYKRVGNGETLNELFELEQGEESSTSELLATLRENNVTASEPYHARLIFEKDGDKAQILENKGDGKDYGVSFVLEEEQSEQEFATFMWLTVFTVAFGLLVLLFLKKLKKLTHGAEDNEHEIMEQEPYELGNPDLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHT3</accession>
    <name>A0A5C6ZHT3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase family 4 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_07870</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="58"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="195"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="370" mass="42951" checksum="16A94F8226F4A894" modified="2019-11-13" version="1">MKKALVHDWYYISGGAEKVIHSFNSVYDDFEHYALVDFLDEKDRQFILNGASVHTSFIQNLPTAKSNHRKFLQLFPYAIEQFDLQDYDLVLSSSASIAKGVLTTQDQLHICYCHSPMRYAWDLYHQYLEDSNLKKGLKGFYAKQVLHKMRQWDISTVNRVDFFVANSKYIARRIKKIYNRESTVIYPPVDVNRFTLQETKKEYYLTVSRMVPYKKLKLIVETFNEMPNKKLIVLGDGPDYKHIKKIAKSNIELKGFMEADDLKVYMQEAKAFVFAAKEDFGIVPVEAQACGTPVIGYNAGGLRETVKDGETGVFFDSQTTEAIKAAVEKFESLTFDANTIRENALRFSTERFEREMKAFIETKYKEFKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHW6</accession>
    <name>A0A5C6ZHW6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MerR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="1">
        <location>
            <begin position="10"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="109" mass="12824" checksum="3371E9C8C1B65E69" modified="2019-11-13" version="1">MHIELPEKRYYGIGEVAKAFEVNTSLLRFWEKEFDVLKPKKNAKGNRKFTPEDIKNLKFIYHLVKERGFTLEGAKTHLKEEKKQSMTTFEIINKLEGIKAQLVKIKSQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHY1</accession>
    <name>A0A5C6ZHY1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Prohibitin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_13230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03401">
        <property type="entry name" value="SPFH_prohibitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000163">
        <property type="entry name" value="Prohibitin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23222">
        <property type="entry name" value="PTHR23222"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00679">
        <property type="entry name" value="PROHIBITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PHB" evidence="1">
        <location>
            <begin position="16"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="259" mass="28891" checksum="DA2883C6447D2FED" modified="2019-11-13" version="1">MKNNFFLLTGVLILFSNCAVIRPGEAGVKQTLGKFSDKVITQGTVVYNPFISKVLKESTQTNNINLVMSLPSKEGLSVDAEISILYRLEQNKIPSVLRNLGQDYEDIITSVFRSASSDVCAKFFAKDMHSGMRADIEREIKLKMDENLEKQADGIELISVLMKRIRLPLGLSNSIEQRLQAEQDAMRMEFVIQQAKLEAERKIIDAEGERDAQIILATGLTPDIIKIKSIDAFNKLSISPNSKIIITDGKTPMLINANE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHY9</accession>
    <name>A0A5C6ZHY9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ESY86_08330</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="41"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="84"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="169"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="271"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="43"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="365"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="399"/>
            <end position="406"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD89386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="611" mass="69437" checksum="34506F951C43DAF8" modified="2019-11-13" version="1">MARRGLQSLSEKKKVNFKGSFSALVFIPRFFKEIWRTNKSLFLGSAFCRLIAAILPVIILWIGKIIIDEIVLQAQVETADLSRLWLYVGIEFGLIVVSDLVSRAISLTDGLLGDAYSIKSSVSIMRKTSKIDMSLLEDSEFYDKLERARTQTTGRVGLMSNALGELQSLISIGTLIAGLIYFEPYLIILLVLSIIPSFINEIWFSQQQYSLARGWTAERRELDYLRYIGANNETAKEIKLFGLTDFIVDRFQRLSQDYFDLNKKLAVKRSALGFVFNVLGTLSYYGAYVFIIYRVVTGVITLGELTFLSGAFNRLTKNLQEFFSKFTRITESALYLKDYFEFIDISIEPKITEDQHLPKTIRLGFEFKDVRFGYPGSDTEILKGISFEMKVGEKLAFVGQNGAGKTTLTKLLLRFYEPTSGAIYLDGININRFNKADYQNYFGVIFQDFFKYEFTARENIAIGDIKELNNQQKIENASELSLANEVISELKKGYDQQLGKRFAKGQDLSGGQWQKVALARAYMKNAEVMILDEPTSALDAKAESDVFQRFIALTKNKTSIIISHRFSTVRQADRILVLENGTVLELGTHQELIENDSLYSELFTLQAKGYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI13</accession>
    <name>A0A5C6ZI13_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Manganese transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_07325</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the bacterial solute-binding protein 9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030001">
        <property type="term" value="P:metal ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006129">
        <property type="entry name" value="AdhesinB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006128">
        <property type="entry name" value="Lipoprotein_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006127">
        <property type="entry name" value="ZnuA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01297">
        <property type="entry name" value="ZnuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00691">
        <property type="entry name" value="ADHESINB"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00690">
        <property type="entry name" value="ADHESNFAMILY"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1 3" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="304" mass="33424" checksum="2BFE69FA961402EA" modified="2019-11-13" version="1">MKKIMSGLLVLLVMANCKTEPKNSNGKLNIVTTTTMITDLVENIGGDKVNIQGLMGSGVDPHLYKASAGDVTKLSNADLIFYGGLHLEGKLVEVFEKMESQNLKTVAVSDALDKSTLIGSEYFASNYDPHIWFDVNNWENITKFVVEKLSMADPENKEFYMENGEQYLKKLENLNTDIKSIIEGLPKEKRVLVTAHDAFSYFGKAYDFEVVGLQGLSTATEAGVQDVQKISAFIIERKIKAIFVESSVPKRTIEALQASVNSKGHHVEIGGTLYSDALGNAGTFEGTYIGMFKYNVKTIVGALQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI31</accession>
    <name>A0A5C6ZI31_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carboxypeptidase-like regulatory domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023006807" evidence="1">
        <location>
            <begin position="19"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="240" mass="27439" checksum="E2DE60F4EA164B1F" modified="2019-11-13" version="1">MRIILLVSFFILSTMVSAQTVSGIVYDSENTVKGARLYNEAQNKLNYTKDDGRFELEATLGDVLIIYSLFHQKLRVTVTPEFYEDVVVFELKQITNALDEVEVHKVIERKYDSTAFQNDLSIPARAPKTPVLRSGSNYEPTLNLISLASAIGRLFKRKKIDVPTIKAADFEKLFKTDSFFTIDFLRKDLQIEEKKEYLFFEYCANQKLAPALLNNQLLMVEALLKCSANFRIAKESPNTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI76</accession>
    <name>A0A5C6ZI76_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Insulinase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_10010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="SSF63411"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M16" evidence="1">
        <location>
            <begin position="50"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_C" evidence="2">
        <location>
            <begin position="185"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="455" mass="50066" checksum="97E834DDF0B22BC1" modified="2019-11-13" version="1">MALLLLGAPVIVVAQSFQLPDYTSFTLENGLVVNLMEQHDVPVIGLTAILPAGAIYDAEKAGLAALTADALKLGTKNYSKTQLDEALDFVGASVYTSARKEYASLNAKFAAKDKDEVLNIIKDILIYPTFDASAFDTEKNRALVAIEQQKESPRRIIDSYFDVLLYGDHVYGNIPQGTAATVGALNASDAEEFYKNNYSPNGASLNIVGDFSSMEMKTMISNLFSAWKKSSNQNENLASKPLSIPTVSNVLLVNKEDAKETTFYIGALGVGRNNPDFVDISIINTLFGGRFTSMLNDELRVNSGLTYGARSRFESLKYGGSFAISTFTANETTEAALDKALEVLNALHSKGLDEKSLTSAKNYVKGQFPPRYETVMDLSGLLGDMFWYDLDKTYINTFEKKVDELDLKKANEIIETYFPKDTLQIVLIGKASEIKEIAEKYGNLNQIEINSYPKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIE2</accession>
    <name>A0A5C6ZIE2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_13070</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007492">
        <property type="entry name" value="LytTR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04397">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00850">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50930">
        <property type="entry name" value="HTH_LYTTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="3"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="HTH LytTR-type" evidence="3">
        <location>
            <begin position="143"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="249" mass="28019" checksum="9F25448307EFBF78" modified="2019-11-13" version="1">MLTAIIVEDLTDALQLLKSDLESQHPDIKIIATAQSVVAAAKALRKQEPDILFLDIMLGDGTGFDVLEIFPKLSSKIIFVTASDEFAIKAFKFAAIDYVLKPYSDQELSEALARAKAQLQPSQERLNILKDSLVSPHKPPERISLHTLDKIIVVNLDEIVRCEADSNNTKFYLQDGQMIFVTKTLKYFADLLKPYGFLRVHQSHLINIKCISAFIKTDGGYLMLKNGQHVPVSVRKKADVIEILDRMHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIF2</accession>
    <name>A0A5C6ZIF2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">M48 family metallopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07395</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002725">
        <property type="entry name" value="YgjP-like_metallopeptidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01863">
        <property type="entry name" value="DUF45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF45" evidence="1">
        <location>
            <begin position="23"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="230" mass="26683" checksum="07FD625308D92BBD" modified="2019-11-13" version="1">MPSVQYGHKTIQYSVLEKAELKSHYISVAKGEGVVLKGKAISDDHARKLILKKAKWIIDKLDLVSYIGDEAIVTGSRIQYLGRKYYVEIFVANDSDEVFIDFTESKFKVTLPKHLHNQTSIQQAFQDFLKVKAEEKITPRLRKWSKTTGLEFNALKFMQLEKRWGSCTPSNNIIINVEAIKLPFSLIDYLIVHELVHTKVKSHSKEFWAELSKHIPNWKELDERMYGMKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIK2</accession>
    <name>A0A5C6ZIK2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type IX secretion system membrane protein PorP/SprF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_12360</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019861">
        <property type="entry name" value="PorP/SprF_Bacteroidetes"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11751">
        <property type="entry name" value="PorP_SprF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03519">
        <property type="entry name" value="T9SS_PorP_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="312" mass="34426" checksum="306C0B01E87E6195" modified="2019-11-13" version="1">MIHKLITYSIFTLILFLGWQAKAQQDPQFTQYMYNMSVLNPAYATADESTINLGTLYRTQWVGSVGAPSTGTLFAHSKLTDRLEGGFSIIHDQIGDVVKETNAYIDVAYVLPAGETAKISFGIKAGATFFSTDFNGFIYSDPLPDPAFAENISRTFPNIGAGVFYFTDAYYLGLSAPNLLQSKHLRDESGIVTEGTENAHLFLTGGYVFQLNERLKLKPAFMTRYIGGAPIAVDLTANVLINDTVELGAGYRFDDSVSALVNFAVTPSLRIGYAYDYTLSNLGRFNSGSHEVFILFNISRLTKGYDKSPRFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIL5</accession>
    <name>A0A5C6ZIL5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">LysM peptidoglycan-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_08030</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the transglycosylase Slt family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008933">
        <property type="term" value="F:lytic transglycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000270">
        <property type="term" value="P:peptidoglycan metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000189">
        <property type="entry name" value="Transglyc_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008258">
        <property type="entry name" value="Transglycosylase_SLT_dom_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01464">
        <property type="entry name" value="SLT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="SSF54106"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00922">
        <property type="entry name" value="TRANSGLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LysM" evidence="2">
        <location>
            <begin position="416"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="2">
        <location>
            <begin position="486"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="532" mass="60756" checksum="C0A6A92020A970D8" modified="2019-11-13" version="1">MKLKLFTLSLAFLCFGRISFSQNPIPQSSEKSRISKADFIDGETYVVDTIIDGKSFYRKEFKIEEALDLAAMKALKDHKIAAAIDQKWLEELYSNNLFDSIYESVTEMDYTEVDYPELPTDTLKLRLEQLNARTPFNIAYNPSLENVIKSYLKHRRNSLSRLMTLSDYYFPLFEESLDNYDIPLEVKYLAIVESALKPRAKSRVGATGLWQFMFATGKEYDLSVSSYVDERSDPVKSTVAASKYLAKLYEIFGDWDLALAAYNSGPGNVSKAIRRSGGYENYWNIRPYLPRETAGYLPAFLATMYIFEFAEEHGFKKERPNYHYVETDTIHVKKMITLDQVSELLEVPIEELQFLNPSYKLDVIPYIEGKNYTLRLPRSVVGKFVSNEDAIYNFAQLEFDKREKPLPQFFDSNSKSTYRVSSGDYLGKIARKYGVRVSQIKSWNGLRSNNLKVGQRLTIYPNNPSASKTPVGTVTPKKTVNSAGKTTYKVKQGDSIWSISQKFPGVSVDNIKEWNDISGNNLKIGTTLIVSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIP6</accession>
    <name>A0A5C6ZIP6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">GLPGLI family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_11385</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005901">
        <property type="entry name" value="GLPGLI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09697">
        <property type="entry name" value="Porph_ging"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01200">
        <property type="entry name" value="GLPGLI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="259" mass="30420" checksum="8462307CFC72D672" modified="2019-11-13" version="1">MNMYKYILLFSVILSFQEGFSQKNKTILVEYQATKNNFKNTETLIAEKDKAIYIIDSLLIENEKNTNIATFDEYSNKITVSQKTIKLDATRFYMNQNSDIIYFTQKFNEEITIIKDSLSSFNWELQNETKKIDDFTCKKARANFRGSEIIAWYTEDIGLPFGPWKFKGLPGLILEVYNVNDTNIFHWSVTKIKFPYTKAVNFNYPEDMKMINYQTVVDDAEEQIKEHLKRSQARVPQGVTLSETTITRSGIEKIYEWEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIQ0</accession>
    <name>A0A5C6ZIQ0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Colanic acid biosynthesis acetyltransferase WcaF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">wcaF</name>
        <name evidence="1" type="ORF">ESY86_09880</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="182" mass="20403" checksum="50E4C6FD75184F72" modified="2019-11-13" version="1">MEIDLSKYNNSWYHPGSKLKLGLWYITNILFFRSSLVPFSSFKGSLLKLFGAKIGNKVVIKPRVNIKYPWFLEIGENTWVGEDVWIDNVAKVTIGKNVCLSQGAMILCGSHDYTKTSFDLMIAPITLEDGVWIGAQAIVPLGITCKSHSILSLKSVATKNLEPYYIYQGNPAKEIRLRTITA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIU9</accession>
    <name>A0A5C6ZIU9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Plasmid maintenance system killer family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_06300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007711">
        <property type="entry name" value="HigB-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40266">
        <property type="entry name" value="PTHR40266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05015">
        <property type="entry name" value="HigB-like_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143011">
        <property type="entry name" value="SSF143011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="78" mass="8947" checksum="692B1F37C8AA5383" modified="2019-11-13" version="1">MITSFGSKNTQNIWNGVKIKTLPIDIQNTGRRKLRMLNNSQDIADLRIPPSNRLEKLSGKLSDFYSIWITKSLWPLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIW7</accession>
    <name>A0A5C6ZIW7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pseudaminic acid synthase</fullName>
            <ecNumber evidence="2">2.5.1.97</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pseI</name>
        <name evidence="2" type="ORF">ESY86_07910</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.97" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016051">
        <property type="term" value="P:carbohydrate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006190">
        <property type="entry name" value="AFP_Neu5c_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036732">
        <property type="entry name" value="AFP_Neu5c_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013132">
        <property type="entry name" value="Neu5Ac_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020030">
        <property type="entry name" value="Pseudaminic_synth_PseI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013974">
        <property type="entry name" value="SAF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03102">
        <property type="entry name" value="NeuB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08666">
        <property type="entry name" value="SAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00858">
        <property type="entry name" value="SAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51269">
        <property type="entry name" value="SSF51269"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03586">
        <property type="entry name" value="PseI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50844">
        <property type="entry name" value="AFP_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AFP-like" evidence="1">
        <location>
            <begin position="290"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="348" mass="38333" checksum="DAC73938F25B414E" modified="2019-11-13" version="1">MKIGTKSIGENHPCFIIAELSANHNGDLNVAIETIRAAKKAGADAIKLQTYTPDTLTIDCDNAHFKIDGGTLWDGKTLYELYGEAYTPWEWHQRLFEVAKEEGLICFSSPFDATAVDFLETLNVPAYKIASFEIQDIPLIEYAASKGKPIIISTGIAQEEDIKLAVETCRNAGNKEIILLKCTSSYPAPLELANLNTIPDLKERFGVTAGFSDHTYGSLAPTVATALGAKVIEKHFILDKSVGGPDADFSLDVEEFTEMVNKVRDTERLLGQVSYEVSEKVEKNRKFARSLFVVKDAKAGESITKENVRSIRPGYGMHPKHFEAVIGKVFCIDVEKGAPLSHKMIEKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ22</accession>
    <name>A0A5C6ZJ22_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="5"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="68" mass="7694" checksum="709315FF07BEDF13" modified="2019-11-13" version="1">MKNSIKVERAKKNITQADLAKLAKVSRQTINAMELGKYVPSTVLALRLAQIFEVEISEIFTLEDSDWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ68</accession>
    <name>A0A5C6ZJ68_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">T9SS type A sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_06225</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023100351" evidence="1">
        <location>
            <begin position="24"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="Por_Secre_tail" evidence="2">
        <location>
            <begin position="252"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="324" mass="34395" checksum="4AA98D32E4786575" modified="2019-11-13" version="1">MGKDVFKSVMTLVCLVFMSLSYAQEFTAENNAIACADGIDNDGDGRIDCIDEDCLGFSGQACQICTEGITFADELIEFQSGCAFVDPEPEGALGMSDYDGSTNDSPTFVALGQGGFIKLGFTNNLLANSGNSGIDVWVFEVGPSVEASDIALRPADDYTETQLINSGVPDVDSDGFYEFGAIGGATNGIDIDDVLMGFEAGTLRFDAIEIKDIPDGSCGGTTPGADIDAVCALSSVTLSTGNKDLNTSSITVYPNPFSSKIKLQHNRSSNTPMAYKIYNMQGQLLLNGLVNNNQELALNNLQSGLYYLTLNIDSKTVSKKILKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ92</accession>
    <name>A0A5C6ZJ92_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_03100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039426">
        <property type="entry name" value="BtuB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30069">
        <property type="entry name" value="PTHR30069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022929584" evidence="5">
        <location>
            <begin position="18"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="7">
        <location>
            <begin position="50"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="6">
        <location>
            <begin position="180"/>
            <end position="608"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD90368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="610" mass="69366" checksum="BD39AA84E60CED4A" modified="2019-11-13" version="1">MKQITTLFLAFATCAIAISQTSLDSIQRLDEVLLSDVKLTRYASGLKIETLTDSVLQKNKRSFTDLLRYNSNIYFKENGYGMVSSPSFRGTNASQTAVVWNGININSQLNGQTDFNLISTSNYSSISIRSGGGSVQYGSGAIGGTVHLNNVLSFDTHFDNELQLGYGSFNTKNAHYKFSYGNKNWSANFGLAYRDSDNDYKYLGSTRTNENAAFNNLDINLNLGYVLSDKDVLKVYHQNFRSDREFSATILAPSKSKYESEDYRSLLEWAHIGNTLSSSLKAVHLLEQFKYFENKDTNNFSKGQANTWQVKHRLTNTFSKQLELSIITDYSYITADGDSFNDPKRNAFSATAILSHSPTQNLQYNLNVRQDVISDFKSPFVFSGDVSYQLASFYTLKFNASKNFRVPTFNDLYWNPGGNLDLKPEDSCQLDLGHEFKYHTIGLKLNTFYIKTSNLIQWRPNQFSGYWNPMNIANAKQYGLEAELALERQIGKHRFDFNLNYSYTKTEDLAKNQALFYVPIHMANAALAYSHKDFSTYYQHLYNGAVKIIGGSLKGFDVGNLGFGYRFKTKSKLSYQADFSIDNLYNTYYENVALRPMPNRNFNLKLTLNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJE6</accession>
    <name>A0A5C6ZJE6_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidase_S24 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015927">
        <property type="entry name" value="Peptidase_S24_S26A/B/C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00717">
        <property type="entry name" value="Peptidase_S24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S24" evidence="1">
        <location>
            <begin position="128"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="233" mass="25854" checksum="CFC1E04781D7D268" modified="2019-11-13" version="1">MAYKFTNIKERALHVAKIHEQSYQDFCAAIGMSYASFKGSAKNRPLNSDAIGNILTTYPKINAEWLLTGAGPISPESTLNEPYQTYKTSKPTEKPEVAIPLYRLEPGEALADLLSNASAIKPIDSIKIPNIQACDAALYITGNAMSPLLKTGDIVAYKQITDFPDDIFWGELYVLSIALANEEYISVNQVQKSELGVKYIKLLSQNEQFEPKDIPLRKLRAMARIKAIIRVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJI3</accession>
    <name>A0A5C6ZJI3_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Copper-containing nitrite reductase</fullName>
            <ecNumber evidence="5">1.7.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">nirK</name>
        <name evidence="13" type="ORF">ESY86_11210</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>Fe(III)-[cytochrome c] + H2O + nitric oxide = Fe(II)-[cytochrome c] + 2 H(+) + nitrite</text>
            <dbReference type="Rhea" id="RHEA:15233"/>
            <dbReference type="Rhea" id="RHEA-COMP:10350"/>
            <dbReference type="Rhea" id="RHEA-COMP:14399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16301"/>
            <dbReference type="ChEBI" id="CHEBI:16480"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="EC" id="1.7.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Cu(+)</name>
            <dbReference type="ChEBI" id="CHEBI:49552"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Cu(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29036"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the multicopper oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.7.2.1" evidence="5"/>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050421">
        <property type="term" value="F:nitrite reductase (NO-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001287">
        <property type="entry name" value="NO2-reductase_Cu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="PTHR11709"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00695">
        <property type="entry name" value="CUNO2RDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02376">
        <property type="entry name" value="Cu_nitrite_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0349">Heme</keyword>
    <keyword evidence="9 11" id="KW-0408">Iron</keyword>
    <keyword evidence="8 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome c" evidence="12">
        <location>
            <begin position="373"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TXD88800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="480" mass="52456" checksum="6C803970478F6323" modified="2019-11-13" version="1">MKTILKLTTFTVALFMFSCMENKGKEYATAEEIPVNREMQAELTSPPNVPRPVGKRKAKKLIVNMEILEQESEITNGVSYVYWTFGGTVPGSFIRTRVGDEVEFTLSNHPDNKLPHNIDLHAVNGPGGGAESSFVAPGYEKTFSFKTLNPGLYVYHCATAPVGMHIANGMYGLILVEPEGGLPPVDKEYYIMQGDFYTKGKNGERGLQPFDMQKAIDEDADYVVFNGSVDALTGDNALTAKVGETIRLYVGNGGPNLVSSFHVIGEIFDKVHVEGGDMINENVQTTLIPAGGAAIVEFKVDVPGSFILVDHSIFRAFNKGALGMLNVEGEERKKIYSGEIREGIYLPEGPTIQAMPTTDEIVESEIPAKNLEEQLKFGKQAYNQTCVACHQAEGQGIANAFPPLAKSDYLNADVNRSIDIVLHGLSGEITVNGDTYNSVMTKQMLSPDEIANVLTYVYNSWDNSGAVVTKEMVLKVKNQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJW8</accession>
    <name>A0A5C6ZJW8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptide methionine sulfoxide reductase MsrA</fullName>
            <shortName evidence="4">Protein-methionine-S-oxide reductase</shortName>
            <ecNumber evidence="4">1.8.4.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Peptide-methionine (S)-S-oxide reductase</fullName>
            <shortName evidence="4">Peptide Met(O) reductase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 7" type="primary">msrA</name>
        <name evidence="7" type="ORF">ESY86_05830</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>[thioredoxin]-disulfide + H2O + L-methionine = [thioredoxin]-dithiol + L-methionine (S)-S-oxide</text>
            <dbReference type="Rhea" id="RHEA:19993"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58772"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 4">
            <text>[thioredoxin]-disulfide + H2O + L-methionyl-[protein] = [thioredoxin]-dithiol + L-methionyl-(S)-S-oxide-[protein]</text>
            <dbReference type="Rhea" id="RHEA:14217"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12315"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:44120"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the MsrA Met sulfoxide reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.11" evidence="4"/>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033744">
        <property type="term" value="F:L-methionine:thioredoxin-disulfide S-oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008113">
        <property type="term" value="F:peptide-methionine (S)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01401">
        <property type="entry name" value="MsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002569">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036509">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01625">
        <property type="entry name" value="PMSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55068">
        <property type="entry name" value="SSF55068"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00401">
        <property type="entry name" value="msrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022667178" description="Peptide methionine sulfoxide reductase MsrA" evidence="5">
        <location>
            <begin position="21"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="PMSR" evidence="6">
        <location>
            <begin position="48"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD90256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="221" mass="24918" checksum="F4CAC460055D2245" modified="2019-11-13" version="1">MKTFLTTLFTVILFSCQNTAQQANLSKEQQEVINADPVAVPMENGMAKAYFASGCFWCVEAIYDSVNGVDDVISGYAGGHTKNPTYESSNTGKTGHAESVEVIYDPEVVSFETLVDVYFASQDVTQVNGQGNDRGSQYRSILFYQNEAQKKIIDEKKSALGAKMNEKIAAEVYPFQKFWIAEDYHQNYERLHPNDGYIRNVSVPRLKRFQAKMPEVLNKNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJY0</accession>
    <name>A0A5C6ZJY0_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Glutaminase</fullName>
            <ecNumber evidence="3 5">3.5.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">glsA</name>
        <name evidence="6" type="ORF">ESY86_03875</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>H2O + L-glutamine = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="3.5.1.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the glutaminase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.2" evidence="3 5"/>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00313">
        <property type="entry name" value="Glutaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015868">
        <property type="entry name" value="Glutaminase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12544">
        <property type="entry name" value="PTHR12544"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04960">
        <property type="entry name" value="Glutaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03814">
        <property type="entry name" value="Gln_ase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0007">Acetylation</keyword>
    <keyword evidence="4 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="240"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD90514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="304" mass="33868" checksum="49AAA0FC98963451" modified="2019-11-13" version="1">MPDYQSILEDIYQKLSLDPDRGEVASYIPELANVDPNAFGIYLQLVNGESYEVGLSQTHISIQSISKVLTLAMAIHIEGLNLWERVDIEPSGNPFNQLSLLELESGIPRNPLINAGALVIADVLVTHFKEPKKEFLEFVRTVTNDQSIDYDQKVLESEFSTGFRNYAAANLLKAYDNLHNDVEEVLDFYFHQCSLSMTCAQLAKAFYMFANKGKDMQGIPRLKKRYVKRINAIMLTSGFYDEAGEFAFEVGLPGKSGVGGGIIALLPNEFVISVWSPGLNEKGNSKLGMEALEMFTTQSNLSIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK69</accession>
    <name>A0A5C6ZK69_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_05480</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="59" mass="6672" checksum="E8D021717074DB34" modified="2019-11-13" version="1">MASEGNIHSLMPNKFTQLVDIFTPAYNDENTAASKWFKVDEKETFEGIPNQYLAEYAVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK91</accession>
    <name>A0A5C6ZK91_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">3-hydroxybutyryl-CoA dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_01915</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006180">
        <property type="entry name" value="3-OHacyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006176">
        <property type="entry name" value="3-OHacyl-CoA_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006108">
        <property type="entry name" value="3HC_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00725">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02737">
        <property type="entry name" value="3HCDH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00067">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3HCDH_N" evidence="2">
        <location>
            <begin position="2"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="3HCDH" evidence="1">
        <location>
            <begin position="183"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="3HCDH" evidence="1">
        <location>
            <begin position="304"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="390" mass="43146" checksum="C2AA9A85B5129DE0" modified="2019-11-13" version="1">MNIGIIGSGTMGSGIAQVAATAGCNVKLFDTNQAALDKAKASLEKILARLIEKGRIDSEEKQRIQNNITYVSQLKDLSDSDLTIEAIVENLDIKKSVFSELETYVSEDCIIASNTSSLSIASIAASLKKPERCIGIHFFNPAPLMRLVEVIPAIQTSKAVLETAVKTISDWKKTVAIAKDTPGFIVNRVARPFYGEALRIYEEGIADFASIDAAMKKLGGFKMGPFELMDFIGNDVNYTVTETVFTAFYFDPRYKPSLTQKRFAEAGYLGRKSGKGFYDYDSNGKAVIPSATKESHDTKLQEQIFNRVLVMLINEAADALFLNIASAEDIDNAMTKGVNYPKGLLAWANEKGIAWCVDHMDELYNTYREDRYRCSPLLRKKLKEGVGFEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKH8</accession>
    <name>A0A5C6ZKH8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Protein-tyrosine-phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_04930</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036196">
        <property type="entry name" value="Ptyr_pPase_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52788">
        <property type="entry name" value="SSF52788"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="210" mass="23738" checksum="8FA0376846B34E2B" modified="2019-11-13" version="1">MTSTQSGVFPALTTTIQSLKPETISESRKKELQPLIDFIQSKVSNQQEIRINFICTHNSRRSHFSQVWAQTFATHFKIKNVFCYSGGTEATALFPTVVDTLRSSGFEIRTLSEGNNPIYSIKYAENEHPIIGFSKKLDADFNPKSEFAAIMTCSQADDGCPFIAGAETRIPITYEDPKVFDHTPQKAEKYSERSRQIATELFYVFNQINS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKH9</accession>
    <name>A0A5C6ZKH9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytochrome C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03835</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025992">
        <property type="entry name" value="Haem-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14376">
        <property type="entry name" value="Haem_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01235">
        <property type="entry name" value="Haem_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Haem_bd" evidence="1">
        <location>
            <begin position="12"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="155" mass="18137" checksum="E87F1057B0D2F2CF" modified="2019-11-13" version="1">MKVVKKILVVLLIVLVIMQFFAPKKNQGDLASLNAFTVETNMPKNVQSIFENTCYDCHSDYTRYPWYDRITPLNYWLADHIEEGKEHFNASSWDRYTIKKKDHKLEELIEEVEKKNMPLESYTYTHAEAKLSDEEIKAVVAWAKTVRAGYNLVSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKJ7</accession>
    <name>A0A5C6ZKJ7_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase_M1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_03260</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="248"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="324"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="367"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="414"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="458"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="482"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="533"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="572"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M1" evidence="2">
        <location>
            <begin position="875"/>
            <end position="1068"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1218" mass="139135" checksum="9354B911317ACD8C" modified="2019-11-13" version="1">MFSTIFFHELKYWFKKPAFYIYMAIFFMMALFFAATTAGIFDGLTASVGSSLIVNSPIGINNLINGLTILIFFLFPSIIGVSVYRDFKSEMHTILYSYPFTKANYLFAKFFSSILIVSLIVLTIAIGMFIGFRLPGTNGDVVGAFAFKSYFDAYWLFVLPNILLFGAIVFAVVTFTRNIAAGFITVILLLFVQGLTESLLSDPSQRYLAALLDPFGSAATAYDTRYWTVFEQNELHIPISDAILYNRLIWLGVASLVFGLVYRFFSFSQNAMTFSLFGSKKSERSTKRNFGGITRVNLPKVSFDHSFFQNLKTTWKISNFDFKFIVKSWPFICIVLVGLIVVLFGLSDLGNPFATPTYPKTWRMLQGGGLFVFAINICTFLYAGLLVNRSKIASMNGLEDVTAIPNWSLFLSKLIAIVKMQIVLLAVVLVAGVLFQTYKGYYDFELGLYIKELFGLKLINYVIWAFLSLAVQTLIRNPYLGLFVMIVLTIGIPLLTLAGIEQDIFKFNESPGFSYNDMNGYGDSLGRYLLYKGYWFIAGLLLLIITALFWVRGLPHGFKERLTIANSRFTTPVATTFVILLLSFFALGFTIFKQTNINNDRYTSKEREQLTVDWEKTYKKYEDYAQPRIVSVKTNLDIFPKKRDFEASGDYLMVNKSNVAIDSVFLNHNDYISTFEFNKPNTLVSEDTIYHFDIYQLKTPLQPGDSLNLHFEIRNKPNTLLVTNSPIVSNGTFVNNTQLFPRLGYSGGELTDDKTREKYGLPPNELKPEPTDSTALGNTYISKDSDWIDFEATVSTSEDQIAIAPGYLQKEWTKDGRRYFHYKMDSKMLNFYAFNSAEYLVKKDKWKDVNLEIYYHKGHAYNLERMMKGMKASLAYNSENFSPYQHKQLRIVEFPSGSFAQSFPNTIPFAGDAGFIADVDDSGDGGIDYTYAITVHEVAHQWWAHQVIGADVLGATMLSESLSEYVSLKVLEQEIGKTQMRKFLKKSLDDYLTQRTFERKRENALMYNDGQGYIHYQKGSLVFYAMSDYIGEKKLNNALQRYVEKVKFQEPPYTTSVDMVNYIREVTPDSLQYLIKDMFETITLYDNRVVKATSKALDNGKYQVDIEFEVSKYRNNEKGRRFYADEGRDSISYTPEGKTRPILSLPLQDYIDIGVFAETEVDGKQKEKELYLKKHKITDIHNKVSIIVDEKPSEVGVDPYNKLIDTRSGDNRERLQGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKQ0</accession>
    <name>A0A5C6ZKQ0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">tRNA-(Ms[2]io[6]A)-hydroxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_03325</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045301">
        <property type="term" value="F:tRNA-(2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine)-hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07910">
        <property type="entry name" value="MiaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010386">
        <property type="entry name" value="tRNA-Hydrxlase_MiaE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42637">
        <property type="entry name" value="PTHR42637"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06175">
        <property type="entry name" value="MiaE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF020736">
        <property type="entry name" value="MiaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="193" mass="22573" checksum="2FDC17A69075E9C1" modified="2019-11-13" version="1">MLGLKLPTDPRWVNIVEKNIEDILTDHAYCEQKAASTAISLIIGFPEYSDLVEEMIALVKEEMSHFKLVHDRILENGWILGRDRKDDYVLALIKFFPKGGSRTTQLVHRLLYAALIEARSCERFRLLSEELKDKELAEFYRKLMVSEANHYTMFLGFARQYGDRKDVDQKWQDLLEYEASIMKELSKKETIHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKV3</accession>
    <name>A0A5C6ZKV3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_09565</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="425" mass="47117" checksum="CEED4F2AF8EB47ED" modified="2019-11-13" version="1">MLWLKLKAGALQLTLFIAVVVALLLMAFILLVHTHKRFQVQTDFIIETVKNADRGIQYALNNTGVLRDSTYIQCDADYKTLKTYRSYWGVFEKITSVSKIKNNTVEKYALVGGQLSKAQRPSLYLSDERKPLVLVGNTRIEGLAYLPEQAVKSGNIAGHSYYGSQLIYGQTRTAYELPDIDEEMGAHLSALEDQSLSIPEDQFLAIEPGKTYKNSFFRPVQIVYSNQDINLGNLKMTGNIIVQSESKITVAATSVLKDIVLVAPEIEIQNKVKGNFQAIASERIVVGENVALEYPSALVVKENESVKDKIEPAGSEKNAITIGAYASIKGVLLFLGQPKPNNYEVQLGIETNASIIGEVYCNQNIELQGTVLGTVYAKNFIAKQFGSIYQNHIYNGQIIATDLPEEFIGLNLTNTSEKGIVKWLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL05</accession>
    <name>A0A5C6ZL05_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF2797 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_02935</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021246">
        <property type="entry name" value="DUF2797"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10977">
        <property type="entry name" value="DUF2797"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="264" mass="30666" checksum="94A7CC45AF38F713" modified="2019-11-13" version="1">MLYQGVLRKMQTEMAAPIQYYLILENDFLNMNQLLDKTIHLQFIKHQCLNCSLNKPIFRQGFCKSCFFDIPQAADWIMKPELSTAHLDQEDRDLVYEKKVQLQPHIVYLANSSNVKVGVTRKSQVPTRWIDQGAHEAIEIVEVPNRYLAGITEVALKNHVGDKTNWRKMLKNDVEDENLVEWREKLKQYIPAEAVDYYIASNTETEIHFPVKQYPEKPKSLNIEKEKSYTGRLVGLKGQYLIFEDERVFNVRGNEGCVVSLALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLK5</accession>
    <name>A0A5C6ZLK5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD(P)/FAD-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05015</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="1">
        <location>
            <begin position="3"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="485" mass="54406" checksum="970E15B0B12318E0" modified="2019-11-13" version="1">MAKIVVLGAGISGHAAASHLRRKLPKEHEVVVVSPNSNYQWIPSNIWVGIGRMKSEKILFPLAPLYKKKHIGYKQAKAVSFYPEGDQKEQKPYVLAEYVFGEQKGQQEKITYDYLINATGPKLNFEATEGLIPGKNKAYSVCTYTHADHAWEGLKKLIEQMKQGKKAKILIGTGHAKSTCQGAAFEYILNVEEELRKHKVRDMAEVTWISNEYQLGDFGMDGMLLSYGSMTMKSHEMIEMIFEDRDIKWILGAGVNKIEDGVAHYENLEGEQKSEIYDFAMLIPSFSGHGFKAFDKNENDITEKLFKGFMIVDANYTPKPYEEWSVQDWPETYQNPTYKNIFAPGIAFAPPHSISKPRKSKNGTEIFPAPPRTGMPSGITAKIVADNIIDTIKNGKESLTHKGSMGNMGAACIASAGFGMTTGSGVSITTYPIVPDYEKYPKTQGRQLSKTFGEIGLAGHWLKLSLHYAFIYKAKMRPFWWLIPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLQ6</accession>
    <name>A0A5C6ZLQ6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Restriction endonuclease subunit S</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_04400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-I restriction system S methylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.220.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000055">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044946">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01420">
        <property type="entry name" value="Methylase_S"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0680">Restriction system</keyword>
    <feature type="domain" description="Methylase_S" evidence="4">
        <location>
            <begin position="28"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="Methylase_S" evidence="4">
        <location>
            <begin position="220"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="412" mass="46155" checksum="689374F1C3980C2D" modified="2019-11-13" version="1">MTNKNTQNEVALAEGKVGYKKTKLGWIPEEWEIVQFKEIAKFNPKAEELPEKFIYIDLESVKDGTLRKENKISKIEAPSRAQRLLENEDILFQTVRPYQKNNLFFKSNGNYVASSGYAQLRAKKCSGFIYQLIYAEYINNQVMARCTGTSFPAISAKDLSGIYVKLPPLPEQQKIATILNTWDKAIAAQEKLIAQKQDLKKGLMQQLLTGKKRFAGFEGEWEEVKIKDIADTFSGGTPSSKKVEYYNGKIPWLKSGELNKGIIKNTTGYISELGLKKSSAKLVEIDTILVAMYGATAGVCGITKIKGAINQAVLALILNKGFSTYFIYQLLKMKMPHIVHSMVQGGQPNLSGGIINSVKVKIPILGEQEKIGELLLNRDYEIDMIRKKLGNMKTQKQGLMQQLLTGAKRVKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM72</accession>
    <name>A0A5C6ZM72_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF853 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_04675</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033186">
        <property type="entry name" value="HerA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05872">
        <property type="entry name" value="DUF853"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF853" evidence="2">
        <location>
            <begin position="34"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="464"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="509" mass="56178" checksum="BD459BB7A8533E03" modified="2019-11-13" version="1">MSKTDDFLAEITAGNTFKGEFITLGSAMLDGKTLTNAYVNIPLKTMNRHGLIAGATGTGKTKTLQVLAENLSEKGIPVVLMDIKGDLSGLAKPSAGHAKIDERHASIGLPFTPKAFPVEVMTLSEQDGVRLRATVSEFGPVLLSRILDLSETQSGIVAVIFKYCDDHKYPLLDLKDFKKILQYATQEGKDEFSDAYGRISTASTGAILRKIVEIEQQGGERFFGETSFEVDDLLRVDDDGRGYINILRLTDIQDRPKLFSTFMLSLLAEIYSTFPEQGDSDRPELIMFIDEAHLIFNEASKALLNQIESIVKLIRSKGVGIYFVTQNPTDVPEAVLGQLGLKVQHALRAFTANDRKAIKLTAQNYPETDFYDTTEVLTSLGIGEALVSALDEKGRPTPLAATMMRAPMSRMDVLTDTELDALISTSKLARKYNETIDRESAYEMLNEKIEAAEAEEAKAKAREEKEALEKASSRGTYRRNSSRQNPLIKVLTSPTVIRSVLGILTKMMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMB3</accession>
    <name>A0A5C6ZMB3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03025</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydrolase_4" evidence="1">
        <location>
            <begin position="50"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="337" mass="39071" checksum="94676D3C44AB2605" modified="2019-11-13" version="1">MKEEIAMGRVSEAYEPDVLGNGFEKLNLKLSNDYEGQVIATLVRRMANNKSEKAILYVHGFNDYFFQKDLAIRFSELGYHFYALDLRKYGRSYLRHQKFNNVRSILEYDEELDLSLKIIKAENNHEILLMGHSTGGLILTNYAVNHLKSELFHGLICNSPFYEFNLNGFERTVGIPILSFIGKYFPNIPISGGFSKRYGYSLHIEKYGEWNYSLLWKPHDIPKVTMGFIRAIRSAQLNIRNKLSIDVPALVMHSDNSVYDKHWSDKFKEGDAVLNVDHIKKYAHKINGDVTLREIEGGMHDLVLSKKPVREQVYKKICDWINNNLNKSQEAILKQRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMB5</accession>
    <name>A0A5C6ZMB5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Chaperone protein DnaK</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">HSP70</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Heat shock 70 kDa protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Heat shock protein 70</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">dnaK</name>
        <name evidence="9" type="ORF">ESY86_06215</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Acts as a chaperone.</text>
    </comment>
    <comment type="induction">
        <text evidence="6">By stress conditions e.g. heat shock.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00332">
        <property type="entry name" value="DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012725">
        <property type="entry name" value="Chaperone_DnaK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="PTHR19375"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="SSF100920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="SSF100934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02350">
        <property type="entry name" value="prok_dnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword evidence="4 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="596"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphothreonine; by autocatalysis" evidence="6">
        <location>
            <position position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD89797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="636" mass="68749" checksum="ED64D88A08BC4FAF" modified="2019-11-13" version="1">MSKIIGIDLGTTNSCVSVMEGNEPVVIPNAEGKRTTPSVIAFVEGGEIKVGDPAKRQAVTNPINTVYSIKRFMGNKYSESKKEAERVPYKVVKGDNDTPRVDIDGRLYTPQELSAMILQKMKKTAEDYLGHEVTEAVITVPAYFNDSQRQATKEAGEIAGLKVRRIINEPTAAALAYGMDKKGIDQKIAVFDFGGGTHDVSILELGDGVFEVLATDGDTHLGGDDVDEKIIDWLADEFKADEDIDLRKDPMALQRLKEASEKAKIELSSSAQTEINLPYVTATASGPKHLVRTLTRSKFEQLIDDLVKRTIEPCQKALKAAGLTKSDIDQVILVGGSTRIPAVQQAVEKFFGKAPSKGVNPDEVVSLGAGIQGGVLTGDVKDVLLLDVTPLSLGIETMGNVMTKLIEANTTIPTKKSQVFSTAADNQPSVEIHVLQGERPMAADNKTIGRFHLDGLPPAQRGTPQIEVTFDIDANGIIKVSATDKATNKTQDIRIEASSGLTEEEINKMKQDAEANADADAKAKETADKLNQADAMIFQTESQLKEFGDKLSDDKKTPIEEALKELKEAYATKDIAVIDPALEKINEAWKVASEEMYKAQASDAQNGGDEPADDAGANEDGKADSDVEDVDFEEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMD0</accession>
    <name>A0A5C6ZMD0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4157 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00465</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025295">
        <property type="entry name" value="DUF4157"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13699">
        <property type="entry name" value="DUF4157"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4157" evidence="1">
        <location>
            <begin position="72"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="483" mass="52739" checksum="76CBEF467552A3A8" modified="2019-11-13" version="1">MKLAETKNPLVANKNIQKKQQPFFNKVGQGGFFSQTKELEKPFFNPYPIQAKLTAGEISENDKDETKNISGLPDSLKVGLEQLSGMDLSSVRVHQNSSKPSKINALAYTQGQEIYLSSGQEKHLPHEGWHVVQQMQGRVKPTLQTKEVSINDNEALEREADVMGTKALQVKGVEQTNVNSQMIGDIGHMASSSRLNTALRHYRNSAVDSASSALIQRVPVAPAVAAAIKALTFAEAITAVGTVVSSAASIVGLVGTAQNDKTGVSNDAIIDPTSGDYLMSDVDRDGLAQVFRVLYFSTVEGLVDKEQSRGTILDDAKQEELKQTALGNVKFSLTRNLAQRLTTTTEEFVQQGDGGTSKETPWGSVKVSVEGSELGNPSTSPPLVEIAERHQVTLPQRPLSFIKRVKLSFESEKDWNLTFNDDIWVRGTKLAPTQGSDLHVGIEAEVAFDWDGDTSRYEWDGPSLITFNNIAQPEWRGPSDPDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZML2</accession>
    <name>A0A5C6ZML2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Conjugative transposon protein TraM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">traM</name>
        <name evidence="1" type="ORF">ESY86_05375</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022187">
        <property type="entry name" value="Conjug_transposon_TraM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12508">
        <property type="entry name" value="Transposon_TraM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="309" mass="35283" checksum="613068B2AB7D8517" modified="2019-11-13" version="1">MKVEKNKIVFAAVLAVIFIFLISYSVIVMGDDESENENLKQTLVPDLDENQKEYDSKLDAINDLKEVRENNAPSIYDEKLIDSLGFYDPNLPELEKKRIVDSIYESGKIQYSEKRYQNFGQKKADRKITKKIDTADIKREQKIEAKELGLEHQLFFAASPKPNDLSIIENTDETIYVIVDGSQVVQANSRIRMRLSKTAQINNITIEKNTPIYGLVSFQPNRTIIKIENINHNPTSLKAFDLQDGSEGIYVENNFRAEVTTEVLDDVISDINIPTVPQVGGITKVFRRSNRNIKVTVLNNYKLILKPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMM1</accession>
    <name>A0A5C6ZMM1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_01660</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="545" mass="61760" checksum="1BE3278252FB095B" modified="2019-11-13" version="1">MKATILNIFFLLSVFFGLAQSEFHVFPMQHKTTPGSTHGDGSLENPWDLQTALNQKPDKVSSGDTIWMHEGIYNGRYMSRLKGETPNQYITVSAYKEDKVVLNGNVPSKQDGVLIVKGDRVLFKNFEITFLGDFSRDESEADFQVCAAIMHLSGVNCMFYNLNIHDNPGLGIGSWRHTAGSTIEACRIYNNGFLSKDGKGRGEGIYVQNMSDEIRLIKDNIIFNNYYKGVEVWSAGKHTSFEYVKNITLDHNIIFNSGTPSGKHVDNVIVASNDRNGINIAKNIRLSNNVLWHNTGDANGSILGDAPALTLGFHKNAPIENVTVHQNIIVGGYNGLRLLYAKSLNFTNNEIYTGNVQIDPSMQSYYTNWNFNSNRIYTKLKKPFRVTRTKDYNLDMWRETFNLDAKSEVLPLTQFELDKMLHLSQQSQNKKLFSVALFNAEGEATTVNFSDYQLKKGTHYQIYDVENPETILKSGMLSEAKEVQFPMQSAAFQKPLHNTSAKKNLSNFGVFRIVFETEAEIEADIEADIKRKRTDFERFLEWLGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMN3</accession>
    <name>A0A5C6ZMN3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_00430</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041289">
        <property type="entry name" value="Bact_RF_family3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="L30e-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18845">
        <property type="entry name" value="baeRF_family3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="SSF55315"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="337" mass="39183" checksum="25F2BE21D709FA6A" modified="2019-11-13" version="1">MNTHRTSPDNEKDTIALKNLCKEAEERLLADERKRDAKLLIKRIQELASQIDHRHNLESLILFVNEDLAEYTRLPFKVKDRIVIDHSFATRDLVRALHQEANYLILVLSQHKVRLIEAFNDKVLKEYSDSFPMENTQFYSTNKAELSNASRQSSLIAEFFNRVDKEVNEVRKTHALPVLICTEQSNYHEYLKVADQKQGLFDMFLNKNRLDEKAQHIVEDAWKILKAHVIERNNAQKQELVKAVSSGKYLSDVNDIYRAILEGRVQTLFIEEGLFQPGLMEDNIIRFVSEKERSKKAVTDDIYDELIEINMNYGGNTVFLPKGELTEFDGFGAITRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMV4</accession>
    <name>A0A5C6ZMV4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_00850</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045607">
        <property type="entry name" value="DUF6452"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20050">
        <property type="entry name" value="DUF6452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="184" mass="20834" checksum="2F73C9532B4A05D5" modified="2019-11-13" version="1">MKAYKPLSLFAIAVFAILVWSCERDDICSENTVTTPRLVIDFYNIANPDEEKAVSSLRVIGLDDEGLAIDTLNLEEGPNPSRIKLPLRFQEAGTLTVTRYLLEKDANLASDDNPNTSSNADLIEIRYTPEFIYVSRACGYKSIFQFGFNGSVLEQTDEDNWIISTEQLIQTVDNEDEVHYILYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN35</accession>
    <name>A0A5C6ZN35_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Biotin carboxylase</fullName>
            <ecNumber evidence="5">6.3.4.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Acetyl-coenzyme A carboxylase biotin carboxylase subunit A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">accC</name>
        <name evidence="8" type="ORF">ESY86_03230</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + hydrogencarbonate + N(6)-biotinyl-L-lysyl-[protein] = ADP + H(+) + N(6)-carboxybiotinyl-L-lysyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13501"/>
            <dbReference type="Rhea" id="RHEA-COMP:10505"/>
            <dbReference type="Rhea" id="RHEA-COMP:10506"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83144"/>
            <dbReference type="ChEBI" id="CHEBI:83145"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.14"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Acetyl-CoA carboxylase is a heterohexamer of biotin carboxyl carrier protein, biotin carboxylase and the two subunits of carboxyl transferase in a 2:2 complex.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.14" evidence="5"/>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00655">
        <property type="reaction ID" value="UER00711"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004075">
        <property type="term" value="F:biotin carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001295">
        <property type="term" value="P:malonyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004549">
        <property type="entry name" value="Acetyl_CoA_COase_biotin_COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CbamoylP_synth_lsu-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00289">
        <property type="entry name" value="Biotin_carb_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00878">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00514">
        <property type="entry name" value="accC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0092">Biotin</keyword>
    <keyword evidence="5" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="1 5 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="2 4 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin carboxylation" evidence="7">
        <location>
            <begin position="1"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="6">
        <location>
            <begin position="119"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU365063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD90393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="479" mass="52880" checksum="6A26ED3C1B3E4D8F" modified="2019-11-13" version="1">MKKILIANRGEIAIRVMRTAKKMGIKTVAVYSTVDRNAPHVKFADEAVLIGEAPSNKSYLLGDKIIEVAKALNVDAIHPGYGFLSENAQFAEACEANDIVFIGPKSKAIKIMGSKLAAKDAVKAYDIPMVPGTDEAIDDIPEAKKIAEKIGFPILIKASAGGGGKGMRIVENASEFESQMDRAISEAKNAFGDGSVFIEKYVASPRHIEIQVMADTHGNIIHLFERECSIQRRHQKVIEEAPSCVLTPALREEMGQAAIKVAKACDYVGAGTVEFLLDENHNFYFLEMNTRLQVEHPVTEWITNTDLVELQIRVARGEELPLKQSDLKIEGHALELRVYAEDPLNDFLPSVGNLKTYKLPVGEGIRVDNGFEQGMDIPIYYDPMLAKLVTYGKTREEAIGIMLQAIAAYEIEGIETTLPFGSFVCEHEAFRSGNFDTHFVKNHFSAEKIKAQQEAEANIAALVAVKAYLKEQRLLKTPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN56</accession>
    <name>A0A5C6ZN56_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_00195</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="210"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="245"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="276"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="300"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="335"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="364"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="10"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD91055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="391" mass="41453" checksum="B5B944918766DE1B" modified="2019-11-13" version="1">MKKINTPSKFLLIVAILAIAFNLRPALSGIGPLAEDIGIDLNLSAAWLGLLTTLPLLAFGVISMLTSLFTKRLGIGKTLLGALVILTFGIVLRSLFGVVGLYAGTLFIGIGIAFGNVLIPALTKQNFPERAGAITSLYSSVMAVGASIAAGISVPLATSYGWGWRGALGIWAVPAFLALVIWSFRVKHIKKTNPRRGFTEALKKLSGTPLVWKMAIYMGLQSLAFYVVLAWLPTILVEDGYTSSYAGWMLSLSQATGILGSIIIPLWAGKRKDQRLIIVILVLLEIISLAGLMFPELGMVSVWVSIIGFVLGGTFGLALLLIVLRSTDADTAAELSGIVQSIGYLIAATGPLLIGIIHDVSQDWNYALVVLIGVSLMKLYAGMGAGKPGQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNJ8</accession>
    <name>A0A5C6ZNJ8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Response regulator transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_00995</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="7"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="134"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="134"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD91195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="242" mass="28232" checksum="2651234EA1BBE2E4" modified="2019-11-13" version="1">MEEQNKKILLVEDDPNFGTVLKDYLNMNDYDVVHAKNGMEGFEKFKKDDFDLCILDVMMPYKDGFTLAKEIREKNADVPIIFLTAKAMKEDVLKGYKVGADDYLNKPFDSEVLLMKIKAIIQRKATDSIADSKQFEFKIGRFDLNSKLRFLKFDGKDPIKLSPKENELLRMLALHENDLMPRELALTKIWRDDNYFTSRSMDVYIAKLRKYLKLDEEVEILNIHGEGFRLVIHNQEASDSDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNK3</accession>
    <name>A0A5C6ZNK3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF302 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_02755</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005180">
        <property type="entry name" value="DUF302"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035923">
        <property type="entry name" value="TT1751-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016796">
        <property type="entry name" value="UCP021774"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03625">
        <property type="entry name" value="DUF302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF021774">
        <property type="entry name" value="UCP021774"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103247">
        <property type="entry name" value="SSF103247"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF302" evidence="1">
        <location>
            <begin position="35"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="128" mass="14306" checksum="276EDF8ACC93BB87" modified="2019-11-13" version="1">MKYYFNKTIKGTFEEVIDKVTIGLKEGGFGILTEIDIKATMKKKLDVDFKKYKILGACNPPYAYKALQAEDKIGTMLPCNVIVQEIEDGVIEVAAVNPMASMQAVENEKLNDIANEITAMLEKVIERL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZP10</accession>
    <name>A0A5C6ZP10_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Response regulator transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_01990</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="3"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="142"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="209" mass="23843" checksum="29DD05E64415083D" modified="2019-11-13" version="1">MIKVLVVDNHPIVTTGFELYFKNHKDISIIKTLGSGVDIFDFVRNHEVDVIISEIELPELNGITAIRAIKKEYGHINIIMFSYHPEEIYAISVIKAGASSYILKSEPLEVIEKAIYDVNKGKIHLSEKMSKHLNYNDTKMSKSRIYKRLSAREVEVLKLLSSGKKNKEIAVELDINEKTVSTYKARLFKKLNVNNLIDLVNQGKQIDLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZP55</accession>
    <name>A0A5C6ZP55_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AraC family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="158"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="278" mass="32736" checksum="372FDE469FD1FB7C" modified="2019-11-13" version="1">MLKTYLPAKILQPYIAFFYTIKCHRSNYDQKISEFCLPSGFGHMGFHLHGSFYIIQNNEKQEFPRFYTVGQQTHNYYMNSDSEFVEFYGITFQPTGLWRLFRLDMPTIANRAIGSQFLFKNKIIKFTKQFEAEQSPKKRIQLIEKLMIKKILAIQPQTNIIECALHKMNESCGCSSISSIVNQLGVSERYFQKNFKKMVGITAAVYNRIVRFNFMFAEMKSEVPIDYKSLAALFKYYDFPHFSKDFKKYCGACPSKFYIHKFELLQQLMTSKASLMER</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZP58</accession>
    <name>A0A5C6ZP58_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_00360</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="94" mass="10922" checksum="B4D436C17364C0F2" modified="2019-11-13" version="1">MVPYLCKAQSYRQDSLQIKSYTLIEYRNNEAKEITLLKVLCDYCSEAQSKAIGDEAVRRSYNDRYNPENRMKDGQKRLAVIIRIAKTDLAAIKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPC2</accession>
    <name>A0A5C6ZPC2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_02535</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.690.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036104">
        <property type="entry name" value="BFN_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003729">
        <property type="entry name" value="Bi_nuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001943">
        <property type="entry name" value="UVR_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02577">
        <property type="entry name" value="DUF151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103256">
        <property type="entry name" value="SSF103256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51658">
        <property type="entry name" value="BFN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BFN" evidence="2">
        <location>
            <begin position="3"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="UVR" evidence="1">
        <location>
            <begin position="170"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="202" mass="22981" checksum="1FF17B29F75495AA" modified="2019-11-13" version="1">MSLVRLNIKGISYSQTQNGAYALILNEMDGDRKLPIVIGAFEAQSIAIALEKEIRPPRPLTHDLFKNFADRYDITVKQVIIHKLVDGVFYSSLICERDKIEEIIDARTSDAIALALRFKAPIFTYKNILDKAGIYLKVNPNKETEEQDSILVDDMVVEEIETSIKDSYKDKSLKELNTLLDEAVANEDYEKAAKIRDEISKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPF6</accession>
    <name>A0A5C6ZPF6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">T9SS type A sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_01135</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012938">
        <property type="entry name" value="Glc/Sorbosone_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011041">
        <property type="entry name" value="Quinoprot_gluc/sorb_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07995">
        <property type="entry name" value="GSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50952">
        <property type="entry name" value="SSF50952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022666772" evidence="1">
        <location>
            <begin position="21"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="domain" description="GSDH" evidence="2">
        <location>
            <begin position="30"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="Por_Secre_tail" evidence="3">
        <location>
            <begin position="388"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD91221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="463" mass="50795" checksum="18E713C87D6A294D" modified="2019-11-13" version="1">MKTIASILFCFTFGFSFSQSIVLETFTTNLSNPVNIKHAGDDRLFVVERSGRIQILNSEGIINSSAFLDIDDRVSNSGGERGLLAMAFHPDYASNGFFYVNYIDNSQNTVISRFTRSTFDTAATSSEVILLQITQPFSNHNGGDLHFGNDGYLYISLGDGGGSGDPGNRAQDLNLLLGKMLRIDVDNTENGNNYAIPPNNPFEGNDDALDEIWAYGLRNPFKFSFDKDNGALWIADVGQGQIEEIDRVTSTTGGENYGWKCFEGTSVYSTANDCTVITHTEPVVEYSHTNGRCSITGGYVYRGLQYPALEGLYFFADFCSNEIGYATETAQDNFDITFVDTFPLGGASAFGQDQNGELYVAGVISGTIFKITATSLSLDNNALSQIRMFPNPAQDQLHFDFKEANSTIHSIEIYSLNGTLVLSSKSFENRLKTISTKTVSSGLYLVEITNINGAKTIRKLMIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPG7</accession>
    <name>A0A5C6ZPG7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2141 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_01190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018673">
        <property type="entry name" value="DUF2141"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09912">
        <property type="entry name" value="DUF2141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="95"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="139" mass="15179" checksum="87EBBE2979F374AD" modified="2019-11-13" version="1">MKTVLLSIAFAIVSSLGFTQEKTGHTIIVTIENVKNDSGKILLGLHDKTTFMKADAVAKGISAIKNGTCTITLENIQPGEYAILALHDENENERMDFEDSGMPAESYGTSNNPRSFGPPIYDDAKFKLGEEDLEISIRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZQE3</accession>
    <name>A0A5C6ZQE3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TlpA family protein disulfide reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013740">
        <property type="entry name" value="Redoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08534">
        <property type="entry name" value="Redoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="239"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="408" mass="45992" checksum="1B0E3576360B5D1D" modified="2019-11-13" version="1">MLKALVYISVLIFLISCKSKPSQSLEAGLWRAELQLTNDEALPFNFEVTAAETLTIFNAEEQIEVHDIGYSGDTVRIQMPVFEGYIEAIHSSNRLKGSFVIESLDRRVPFSAEFGKEFRFESTSKESLENVSGTWEALFSPNLEADRYLAKGVFKQDGSKVTGTFETTTGDYRYLEGVMDGDVMKLSTFDGAHAFLFTAKVTDSTMNGKFYSGNHWEEPFTAKRNPSYELPDANALTFLKDGYERLEFSFPDASGKIIALSDERFKGKVTVVQLMGTWCPNCLDESRFYAEYDNANLTKDMEFVALAFEYAKTEAEAFESITRLKNEVGINYPILLAQYGSSSKLQAEEKLPMLNHVLSYPTTIFIDKKGKVRKIHTGFNGPATGEKYSDFKVEFDDFINELLAEEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6Z9W5</accession>
    <name>A0A5C6Z9W5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19775</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000047">
        <property type="protein sequence ID" value="TXD86610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022763413" evidence="1">
        <location>
            <begin position="20"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="351" mass="41138" checksum="813B2BBE5BB31C8E" modified="2019-11-13" version="1">MRKLLSIFILLTISFSSFAQEVELGTIFTIEFSNPERNMDFKIVAKNPYNKLIETNLNMDSIFPKRPKENQIVGVFANGKFGTKVSPILLLVSGMEDYLDYYLRIKIPSKNKFQKTSSISLFKGVKSIEHWPYQIEKIAFKKFKILPKQNIEIFQFKEKIDSTCIKNSAKTIEFGEKEFKAHLKLAISEFHNNKNFELGKMTEYENSINSEDVSLGHFWTLGEGIYPNEKGFKFGNPKSYRRIECPYFEGKSSYFYTKENKNIKVVSFNWETFKESNFGINPEIKNDVNEKFNEKFEYILKTVNSLLGNPIENITEESGQIKIRWKNQKGINAYLFNFGNYNEIRLYVYKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZA86</accession>
    <name>A0A5C6ZA86_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF488 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19145</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000037">
        <property type="protein sequence ID" value="TXD86810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007438">
        <property type="entry name" value="DUF488"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04343">
        <property type="entry name" value="DUF488"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="80" mass="9228" checksum="C84AF2EC0989AE95" modified="2019-11-13" version="1">MHKLKIKRVYEDASTADGYRILVDCIWPRGVSKEDAKLDDWIKEIAPSDDLSNNGPIAVLPQKMFGRLRIPKLHYARLLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZB20</accession>
    <name>A0A5C6ZB20_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_20270</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000062">
        <property type="protein sequence ID" value="TXD86419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="128" mass="14846" checksum="2CC141EA5735F90C" modified="2019-11-13" version="1">MKNMKIIGILFLTFLFINSCRSDDDSNDGNSFCEKERVLNENIENITAELIYLDSKNKYALRFYPNFPTIDEVTYSVLCIQPEGISIDDAVKFTGELYFFNSNENFNPSVGGENFYFTKIEQIQKLNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZB73</accession>
    <name>A0A5C6ZB73_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_17585</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000027">
        <property type="protein sequence ID" value="TXD87246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007492">
        <property type="entry name" value="LytTR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04397">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00850">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50930">
        <property type="entry name" value="HTH_LYTTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="6"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="HTH LytTR-type" evidence="3">
        <location>
            <begin position="148"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD87246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="247" mass="28276" checksum="E2B12733B1D86E36" modified="2019-11-13" version="1">MATPVKILIVEDEMIIAANISLQLSTLGYEVTGIIPRGEEALINIKQDQPDIVLMDIALKGELDGIETVQIMQNDHDIPVIYLTANADDSNFNRAKATNPYAFISKPFKKLDLQRAIELTINQIHCRKDSESSATMTNNSSFILSDCIFVRHHEKMVKVDIKDILYIEAERNYCRIYSKDREYLLVMTLKEMDEKLPQKHFIRVHRSFIVNISQIDEVATSHIVIARKAIPVSKTLKEELLNRLHTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBL3</accession>
    <name>A0A5C6ZBL3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_18610</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000032">
        <property type="protein sequence ID" value="TXD87003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="330" mass="38606" checksum="9F5629D8E42D5E1E" modified="2019-11-13" version="1">MSEDQVHRNNAFTRRFPHHPISKLYDLDLGYNSYYISGYVDNQLYLGNRTAPLHLLKIDLASQDTTHIKINLNKKNLPFRSAEIKIVSPYFFLLDGTVPAVFRGKIGMWEANLWDERDIYFSKAIPMDSTTLFVKSTSSRTFESILGIVDLDKSSDILFKEDLLEKQIDGVFDVDGIMVVSDDDKFIGYVYYYRNEFMIMNNDLELETRMRTIDTVRTAQISLSTNIKKLKITMNAPPVYINKNAYMTNNLMLIHSDRIGKFEEKVMHNQAAIIDIYDWTKSTYELSFYVYNLNESKLREFEVHDEYFVSLIGNSLSLYKLKPTHFKMRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBL5</accession>
    <name>A0A5C6ZBL5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Aspartate carbamoyltransferase</fullName>
            <ecNumber evidence="5">2.1.3.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Aspartate transcarbamylase</fullName>
            <shortName evidence="5">ATCase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">pyrB</name>
        <name evidence="9" type="ORF">ESY86_17150</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>carbamoyl phosphate + L-aspartate = H(+) + N-carbamoyl-L-aspartate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20013"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:32814"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="EC" id="2.1.3.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.2" evidence="5"/>
    <dbReference type="EMBL" id="VORO01000025">
        <property type="protein sequence ID" value="TXD87396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00116"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016597">
        <property type="term" value="F:amino acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004070">
        <property type="term" value="F:aspartate carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1370">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00001">
        <property type="entry name" value="Asp_carb_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006132">
        <property type="entry name" value="Asp/Orn_carbamoyltranf_P-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006130">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036901">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002082">
        <property type="entry name" value="Asp_carbamoyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006131">
        <property type="entry name" value="Asp_carbamoyltransf_Asp/Orn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11405:SF16">
        <property type="entry name" value="PTHR11405:SF16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00185">
        <property type="entry name" value="OTCace"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02729">
        <property type="entry name" value="OTCace_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00100">
        <property type="entry name" value="AOTCASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53671">
        <property type="entry name" value="SSF53671"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00670">
        <property type="entry name" value="asp_carb_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00097">
        <property type="entry name" value="CARBAMOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="OTCace_N" evidence="8">
        <location>
            <begin position="8"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="OTCace" evidence="7">
        <location>
            <begin position="156"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD87396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="309" mass="34493" checksum="155DBA6245755767" modified="2019-11-13" version="1">MSELSVNHLLGIKYLKKQDIQLIFETADHFKEVINRPIKKVPSLRDITIANLFFENSTRTKLSFELAEKRLSADVINFSASQSSTKKGETLIDTVNNILSMKVDMVVMRHPNPGASVFLSQHVNSSIINAGDGAHEHPTQALLDSYSIRERLGEVKGKKVVIVGDILHSRVALSNIYALQLQGAQIMVCGPKTLLPKYIDTLGVQVETNLRKALNWCDVANMLRVQNERMDMSYFPSTREYTQQYGVDKQLLNSLDKPITIMHPGPINRGVEITSDVADSDQAIILDQVQNGVAVRMAVIYLLAAKIKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBQ6</accession>
    <name>A0A5C6ZBQ6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_16880</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000024">
        <property type="protein sequence ID" value="TXD87453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="4"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="276" mass="32190" checksum="35BF54BD6C5911DF" modified="2019-11-13" version="1">MRISIITINYNNLEGLQKTMRSVLDQTYPDIEYIVIDGGSTDGSKAYIESCQQDLAYWISEPDKGIFHAMNKGIEKTTGEYLLFLNSGDTLYSDSVIVESANRMNDDSDIYYGNVLRHYKHQQPLLKIYPAKLDFSFFIDSALPHQAVFSKRSLFSTIGYFNESYEIASDWELLTCAICKYNCSYRYLDIIISNYDMTGVSSQKSSQIIFKKERRTTYVKYFPAFMNDYERFRYDHKFIKAHKLNKLKSISQSKILIKVHQFVLNLLYLLSKKANF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBS4</accession>
    <name>A0A5C6ZBS4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Putative mRNA interferase YoeB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_20145</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the YoeB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000058">
        <property type="protein sequence ID" value="TXD86460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009614">
        <property type="entry name" value="YoeB_toxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38039">
        <property type="entry name" value="PTHR38039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06769">
        <property type="entry name" value="YoeB_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143011">
        <property type="entry name" value="SSF143011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02116">
        <property type="entry name" value="toxin_Txe_YoeB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00030388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD86460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="85" mass="10472" checksum="AFAE2A2E228D9880" modified="2019-11-13" version="1">MKYVFVDESWEDYLYWQKTDKKKLKKINELLKDIARNPFDGIGKPEPLKHKYAGFWSRRIDSEHRLIYQYKEGEILIAKCRFHYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC09</accession>
    <name>A0A5C6ZC09_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17795</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000028">
        <property type="protein sequence ID" value="TXD87168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="311" mass="35021" checksum="608D11267A1F3588" modified="2019-11-13" version="1">MKIFKRIVLALLVLIVVSFIGGYFYFDNKFTPAENYLTVQGVSKKVPLKWVSSDSNPNVAMLLPVKLEGVSQIFYMQLDFGSPTTLMYSNALKSINEKFPSALDLKDDSQIASVQFGLGKMTISSDKFEVLHYGNEVKWDQEAINVIGTLGTDLLEKRRITLNFKEDYCLFDVNGNQNGFTAFEFEKRRLLFPAKIANENLKLLYDSGTSGYEFITDQNEWEKYRVKDGKTKSEKANSVGNTLTVISAPAQETIEIGSKSLSLSEVTYIEGTSAVQNILMRFSGMQGMIGNKLFLNQTLIIDCKTEKFKIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC45</accession>
    <name>A0A5C6ZC45_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF1800 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_18170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000030">
        <property type="protein sequence ID" value="TXD87059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014917">
        <property type="entry name" value="DUF1800"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08811">
        <property type="entry name" value="DUF1800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="456" mass="53018" checksum="283B64BFA671B4D8" modified="2019-11-13" version="1">MERRDIQHLYARAGFGASKPLLDASVSMKKKAIVDHLFETSEAIIPLEIDLSAFTNLSNQDLKNKALIRELRKKSRGELQTFNHRWMERLHTSEGVFREKMTLFWANHFVCQDNNIVYAQAYNNTLRTHALGNFREFVKAISKEAAMLRYLNTKQNRKAKPNENFARELMELFTLGVGQYSEKDIKESARAFTGYNHDLKGDFKFREFQHDAGEKVFFGKTGNFNGDDIINIILEQKECAHFICGRIYRYFVNDNVNNKHVEALTEVFYKDYNIENLMRHLFMADWFYEENNIGSKIKSPVEFLVGLQQLVPFTFDKTKDLIKIQKLLGQVLLYPPNVAGWKGGKNWIDSNTLMLRLKSPSIILANTHISIQEKGEFEDSFDKFYSESKKKQFIKATIAWEVFDKTFDGVSYDELQSYIILPKISGGTQSYLTSLNQNSQRNFCVQLMSLPEYQMC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC58</accession>
    <name>A0A5C6ZC58_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_20500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000081">
        <property type="protein sequence ID" value="TXD86211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="73" mass="8413" checksum="F05CFD9700DBD120" modified="2019-11-13" version="1">MNEKMLVENTYIGSSTTNETSTQVYGFKASRFENKQARFKRDTGSSEAIVGVFHQQSQQSKTRVNLNRNYLFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCH7</accession>
    <name>A0A5C6ZCH7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19475</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000041">
        <property type="protein sequence ID" value="TXD86722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023131567" evidence="1">
        <location>
            <begin position="26"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="61" mass="7105" checksum="752B898725809477" modified="2019-11-13" version="1">MNFTSRLCYRLFLPILIFGSLQMYSQTANTDFANQINTVFQNFDKNRLAHGFLSDFGLDFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCL0</accession>
    <name>A0A5C6ZCL0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17815</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000028">
        <property type="protein sequence ID" value="TXD87171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022729248" evidence="1">
        <location>
            <begin position="17"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="78" mass="8658" checksum="F901C414652056F8" modified="2019-11-13" version="1">MRKLLLLSLLPILSFAQTQIGNDIDGEAIGDASGRTLSLSANGNVIAIGAFYKYRFSSSKIFINKHPTLHKHWSRRSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCR8</accession>
    <name>A0A5C6ZCR8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein translocase subunit SecE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 8" type="primary">secE</name>
        <name evidence="8" type="ORF">ESY86_16290</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the SecE/SEC61-gamma family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043952">
        <property type="term" value="P:protein transport by the Sec complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00422">
        <property type="entry name" value="SecE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005807">
        <property type="entry name" value="SecE_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038379">
        <property type="entry name" value="SecE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001901">
        <property type="entry name" value="Translocase_SecE/Sec61-g"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00584">
        <property type="entry name" value="SecE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00964">
        <property type="entry name" value="secE_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0811">Translocation</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD87591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="63" mass="7229" checksum="2CF113A246ABF304" modified="2019-11-13" version="1">MAGMANYIKESFGELKNNVTWPSWPEAQRLTILVAVFSIIFSLIIWGVDTVFSEVIRAYFNLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD33</accession>
    <name>A0A5C6ZD33_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_17210</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000025">
        <property type="protein sequence ID" value="TXD87407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024671">
        <property type="entry name" value="Atg22-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11700">
        <property type="entry name" value="ATG22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="75"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="192"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="260"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="284"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="322"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="347"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD87407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="374" mass="42201" checksum="52CFE2159E88A93F" modified="2019-11-13" version="1" fragment="single">CRKSKTPCYQGNNLHHHNQLRAATKFSEIIRFLTWVSQRRKQVGYWGSLVFYNSYLPDIAYPEQQDRISAKGFSMGYLGSVLLLLLNLAMVMQPQFFGFDVSIAETITNTGTQAEIDQAMAAAQNEASFEAMRIAFITVGIWWILFSQYTFYVLPKGSSKGQKVTKAIVFNGLKELRLVWIQLKQNLRLKRYLAAFFVFSMAVQTIMLVAVYFGEEEIAWGGPDAKRFGLITSILVIQLVAILGAVLTSRASAKFGNIKTLIVVNFIWMGLCFYAYFMKTPMQFYIAASAVGFVMGGIQALARSTYSKFLPETKDTTSYFSFFDVAEKIGIVIGMVIFATIDQVTGSMRNAILFLFVFFLIGIVLLFRVPRENV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD65</accession>
    <name>A0A5C6ZD65_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Rhodanese-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_16410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="15"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="104" mass="11614" checksum="D79B2431FE91F7AB" modified="2019-11-13" version="1">MADLTQNEWTSQLESNPDAVILDVRTQEEVDEGSIPNALHIDIHKGQGFLDELEKLDKNQTYLVYCRSGNRSGQACTIMNQLGFESAFNLMGGINEWAGPIENK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD80</accession>
    <name>A0A5C6ZD80_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19965</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000053">
        <property type="protein sequence ID" value="TXD86528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="179" mass="19232" checksum="43F92586DD3E0BC5" modified="2019-11-13" version="1">MKNLLLLLTITLTLSCCKKDDDQSTNPIDQLPPATQTGEQTFGCLINGEAFVPPSFGSNSPSAFYQFVNGAYTLGISASKGGGNELKSILLGALDVPNIIETNYLLKSEQSGNFIGKYLIGGGIISNSVTTDENPGTLIITNFDQDNFIISGSFEFTVIDNDGNEVHITDGRFDMNYTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDB7</accession>
    <name>A0A5C6ZDB7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2188 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17735</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000028">
        <property type="protein sequence ID" value="TXD87157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018691">
        <property type="entry name" value="DUF2188"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09954">
        <property type="entry name" value="DUF2188"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="15"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="76" mass="8473" checksum="B4F7B877623B0DA2" modified="2019-11-13" version="1">MGKNQHVVKGNDGWNVKGENNSKATSNHKTQKDAIGRAREIAKNQKSEVVIHGRDGKIRDKDSYGNDPNPPKDKKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDC0</accession>
    <name>A0A5C6ZDC0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4138 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17855</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000028">
        <property type="protein sequence ID" value="TXD87179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022298">
        <property type="entry name" value="Conjug_transposon_TraN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13595">
        <property type="entry name" value="DUF4138"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022742331" evidence="1">
        <location>
            <begin position="20"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="277" mass="32269" checksum="904CB32D3C152160" modified="2019-11-13" version="1">MKHLILIPSILLLIIKANAQEQIALDTIYANDQNNVALFFPEPIRQGIVGSDNFVFTYNQENEQYFGLLQAKPSQESNLLVINKNGSIFSYIVMYKKQLSKLNYFISETGSIGNEKPMPPDSLNAVEPIEQIDNNRFHYQKFCSFLLDQRQGLTTVTKRDQKIILQLENIVFDKNELYFIVSITNKSNLAYDLNFLKFSIQTRQKGKKKSVQELYQEPLFVYNVPERIEANETTRLVYVMRKFSISNDRRAVLKLNEKNGERNLKLKISHRYINNPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDG5</accession>
    <name>A0A5C6ZDG5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">T9SS type A sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_14790</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004062">
        <property type="term" value="F:aryl sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010262">
        <property type="entry name" value="Arylsulfotransferase_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05935">
        <property type="entry name" value="Arylsulfotrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022955015" evidence="1">
        <location>
            <begin position="19"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="domain" description="Por_Secre_tail" evidence="2">
        <location>
            <begin position="471"/>
            <end position="537"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="539" mass="59485" checksum="C271DF7342DE3231" modified="2019-11-13" version="1">MKKITIFLLCFYSNLLSAQNTMGAVSIAPDVFDGYTLFTAHTKTYLLNNCGALINEWDSEYLPGNAVYLLPNGNLLRAGQVDDDSSNITFGGQGGIVELFDWDGQLLWSKRYNSNSIRQHHDVFPMPNGNILILAATVITNQEAIDLGRDPSKLTEGRLYNERIFEIEPVGTDAANVVWEWNIQDHLVQDFDAQKSNFGNVAMSPKKLDVNFLNAGNGASNWLHFNSIQYDETLDQIVISSRNLSEIYIIDHSISTIEAATTAGDFLYRWGNPQAYRQGLASDRKLFGQHSPYYIQEGLEDAGKLMLYNNGNGRTPLYSEVLILDPPTTAPGVYDYSPNTAFGPIAADYSYADLSATPSPFYSGILSSAQRLPNGNILVCEGINGEIFEINANDELVWKYINPINTANGSPGIQGNPPPSTNLIFRAKKYAPDFPAFVGRDLTPGQALEQNPNSICNDLGIASHDFQAVEMYPNPTSGQLYIRSTHPIESIKVYSLLGALVSETRSFSKSINLSDLNAGIYICQINTGTKRVSKKIIKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDI7</accession>
    <name>A0A5C6ZDI7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Two-component system sensor with a ligand-binding domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_17630</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000027">
        <property type="protein sequence ID" value="TXD87255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011110">
        <property type="entry name" value="Reg_prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011123">
        <property type="entry name" value="Y_Y_Y"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07494">
        <property type="entry name" value="Reg_prop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07495">
        <property type="entry name" value="Y_Y_Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022709116" evidence="2">
        <location>
            <begin position="24"/>
            <end position="1011"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="786"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="domain" description="Y_Y_Y" evidence="3">
        <location>
            <begin position="716"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="domain" description="HisKA_3" evidence="4">
        <location>
            <begin position="818"/>
            <end position="876"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD87255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1011" mass="116402" checksum="45CE2E9B644B571C" modified="2019-11-13" version="1">MLSLFRKIVPVACFYFAFLNALIAQNPSQIDVFTTEQGLPYRDIKSITQDKNEFIWMGTALGLLRYDGYNIKTYNSNKSNSLFIEEEYIMAGLDFDDATNDLWYIANGELFTLNPLTDKSIAYDKTHNIMGSVLFLLKNKDGSFWIISDDFKTAKKGKAKQYLQKFNGDRFEIKHAILRGKVDYIRLISDYRGHILWSTPNGSLKFDPDGNLEANFDLSSFKWLGTDLKFNVSFYDSCNNHYFFPQQERGIYIFDEDNLTHKRILDKPIQFYNAIEDYQKHVWFAGLDELYRMSPEGEFTDYTAQLKARFEYSIIRDLFIDANKLLWVATDNGSFKIRIGDELFKPLFKSNTEGWGNTMRGIFEDKNGTIFAKCENSNTLLYKTLNGEVDTLQIQLDKVDLEAMQHTANFFVVDNKKEHVFTLGETLMKINLKDGSVKSYDEFRNYVTFKGQNPLIKLRDGKLLFGQSLSQLVLFDIENETSTLLFKDSEIEDDISNFMYFEESKTDSLIWIGTQNDGLLKVHLNGRLEKQFTIKTTPNISRNCIRALEEDTDGSLWVGTYGGGLNHISADGNTVKTFTKSQQLPNNNVVGLLSDHANGLWISTYNGLSHFDKTTEIFQNYYTEDGLTHFEFNYASFFKDSRGNFYFGGMNGLNRFEPKEIVRESNPPKLSLLSASGYNNQNKSSFIADYNKTKFSALELSPYDQYFEIKWTMTSYFQNQKNTFSTKLEGLEDRWFYQGNSASIRYNQLPAGNYTLKIKGKDSRGIDSASVLSIPITVRQIFYKEWWFILLVLLTVIGLMYAVFRYRLQQVLAMERLRTKISSDLHDDVGSLLSGLAMQTELMEINANQADKFKLQKIAEISRNAVSRLRDLVWSIDSRRETVGDLIERMQELAEEVLLPAQISFQIDSTSVKNPSRKLLAQTKQHLFLIYKEAITNILRHSNATEVHIKFVNYTNSCDLVILDNGCKKETYKSTGLGLDNMRMRAESIKGCVDFKQDDGFSVVLHLPFSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDJ8</accession>
    <name>A0A5C6ZDJ8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Anthranilate phosphoribosyltransferase</fullName>
            <ecNumber evidence="3">2.4.2.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 6" type="primary">trpD</name>
        <name evidence="6" type="ORF">ESY86_16375</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the transfer of the phosphoribosyl group of 5-phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>diphosphate + N-(5-phospho-beta-D-ribosyl)anthranilate = 5-phospho-alpha-D-ribose 1-diphosphate + anthranilate</text>
            <dbReference type="Rhea" id="RHEA:11768"/>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <dbReference type="ChEBI" id="CHEBI:18277"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="EC" id="2.4.2.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="3">Binds 2 magnesium ions per monomer.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the anthranilate phosphoribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.18" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00041"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004048">
        <property type="term" value="F:anthranilate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1030.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00211">
        <property type="entry name" value="TrpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005940">
        <property type="entry name" value="Anthranilate_Pribosyl_Tfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000312">
        <property type="entry name" value="Glycosyl_Trfase_fam3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017459">
        <property type="entry name" value="Glycosyl_Trfase_fam3_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036320">
        <property type="entry name" value="Glycosyl_Trfase_fam3_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035902">
        <property type="entry name" value="Nuc_phospho_transferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43285">
        <property type="entry name" value="PTHR43285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02885">
        <property type="entry name" value="Glycos_trans_3N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00591">
        <property type="entry name" value="Glycos_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47648">
        <property type="entry name" value="SSF47648"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52418">
        <property type="entry name" value="SSF52418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01245">
        <property type="entry name" value="trpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="1 3 6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="Glycos_trans_3N" evidence="5">
        <location>
            <begin position="3"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_3" evidence="4">
        <location>
            <begin position="73"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoribosylpyrophosphate binding" evidence="3">
        <location>
            <begin position="82"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoribosylpyrophosphate binding" evidence="3">
        <location>
            <begin position="89"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoribosylpyrophosphate binding" evidence="3">
        <location>
            <begin position="107"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="79"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>anthranilate</name>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>anthranilate</name>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="223"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD87606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="329" mass="35644" checksum="5A4E79C5E4791410" modified="2019-11-13" version="1">MKNILNRLINQESISAEEAKNVLVNMSEGIYNQSQMSSFLTVYMMRNITLEELQGFRDALLELCIAVDLSNFNAIDLCGTGGDGKNTFNISTLASVVTAGAGVKVAKHGNYGVSSASGSSNVMEALGVKFTNNEDALKRSIDQAGICVMHAPLFHPAMKHVAPIRRELGVKTFFNMLGPMVNPAFPPNQMVGVFSLELQRLYAYLYQNTDKNYSIVHALDGYDEISLTGDAKIISNKTERMFSPSDLNLETIEADKIFGGNTVEDATKIFKQIISGKGSEAQNNVVCANAGLAIATVNGISHETGFELAKESLQSGEALKSLKRLIELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDT9</accession>
    <name>A0A5C6ZDT9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">M20/M25/M40 family metallo-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_17650</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Golgi apparatus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Lysosome</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000027">
        <property type="protein sequence ID" value="TXD87259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005764">
        <property type="term" value="C:lysosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070573">
        <property type="term" value="F:metallodipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039866">
        <property type="entry name" value="CPQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12053">
        <property type="entry name" value="PTHR12053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022866517" evidence="7">
        <location>
            <begin position="19"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M28" evidence="8">
        <location>
            <begin position="259"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD87259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="467" mass="50958" checksum="BA8D221DBC5FE0BA" modified="2019-11-13" version="1">MKQLLYTALLLFGLTTFAQTDADNLKKIYTTSLTNGMSYEWLDHLSNQIGGRLSGSLNAERAVAYTKEELEKLGLDKVWLQPVMVPRWVRGAPEFAYIETSPGVTTNLNICALGGSVATPLGGVKASVVEVMGIEELAALGKDKISGNIVFFNRPMQADLIQTFEAYGGCVDQRYAGAMEAAKYGAVGVIVRSMNLRMDDFPHTGAMSYGDLPNNQRIPSAAISTNDAELLSGMMALNKNTKLFFSQNCTQLADVESYNVIGEVTGSEFPNEIIVVGGHLDSWDLGDGAHDDGAGVVQSMDVLRLLKESGITPKRSIRAVLFMNEENGLRGGKKYAEVAKTKNEKHIFALESDSGGFTPRGFSFDCSDAMMVKIESWIPLFKPYLIHYFEKGGSGADIGPLKDDNIVLAGLRPDSQRYFDYHHAANDTFEAVNKRELELGAASMAALVYLIDKYGTETISSETKLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE89</accession>
    <name>A0A5C6ZE89_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">OsmC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_18275</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000030">
        <property type="protein sequence ID" value="TXD87080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003718">
        <property type="entry name" value="OsmC/Ohr_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036102">
        <property type="entry name" value="OsmC/Ohrsf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02566">
        <property type="entry name" value="OsmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82784">
        <property type="entry name" value="SSF82784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="140" mass="15740" checksum="1EFB299CB2DC6059" modified="2019-11-13" version="1">MSDKVVTHWKGALQFESDNPSGKLLSMDASSEAGGYNSGLRPKAMMLSSLAGCSGLDVVAILKKMKVPFSDFRIDTYGELTNEDPKYYHKVSVEYHIYGDQLDEKKIEKAVNLSVEKYCGVMEMFRQFAEVKTSIHYHNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEE1</accession>
    <name>A0A5C6ZEE1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SusF/SusE family outer membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_12835</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001070">
        <property type="term" value="F:starch binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032187">
        <property type="entry name" value="SusF/SusE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16411">
        <property type="entry name" value="SusF_SusE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022909293" evidence="1">
        <location>
            <begin position="22"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="Por_Secre_tail" evidence="2">
        <location>
            <begin position="254"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="326" mass="35895" checksum="F4D40D8C23E128EF" modified="2019-11-13" version="1">MKKTTITFLVLFVTGLFAVNAQDYMGIVGDATPIGFTPTGLAMAQDSGNPDLFTYEGVLKPGRFKFHLVEADWCVGEWLNAGVEDQDLASNNYITTTGCDGPDNQWLVSTSGSYSIVVDLGLETISISTLPYYPNLYLVGDATPNGWNMDNATPMTVDSSNPALFTWTGPLVAGEFKISTAKSFDDGWDWIHPVAQAQDLTLDTYEILAAGSGSDNKWVISNPDDYTFTLNLQNATLQIEQGTLSVDNFHKIEMYPNPVSQFINLDFKNIVEAKAVIFDAKGSKIYEKKLNSSSNYLDLSNLNVQGLLFLQITSETYSETFKIIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZES4</accession>
    <name>A0A5C6ZES4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Mechanosensitive ion channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_17540</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000027">
        <property type="protein sequence ID" value="TXD87238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011066">
        <property type="entry name" value="MscS_channel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011014">
        <property type="entry name" value="MscS_channel_TM-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82689">
        <property type="entry name" value="SSF82689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82861">
        <property type="entry name" value="SSF82861"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="34"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="80"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD87238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="306" mass="34649" checksum="426CB5D82DA15A8A" modified="2019-11-13" version="1">MQDLKKIEDKISESGAWEGLKTFFGQYIDVTENITISIFDMLLLVVVIFLTTIILRLVFRLLTRKLPKEEKDKFKVVFGYFRWLIYLVIFFVTLNSLGVNITAVFAASAALLIGVGLAMQTLFQDIISGVLILVDQTVHVGDVIEIEGKVGRVVEIKLRSTRAMTIENKVLVIPNHLYLTNSLYNWTQNGVLTRESVEVGVAYGSDVQLVKKLLLEAATSHEEVVSEPKPTVVFTDFGESSLNFKVVFTLGDSFRAQFPKSDIRFEIDRLFREHQVVIPFPQRDLHIIQAKDQTLGLHVNTSKVKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZES6</accession>
    <name>A0A5C6ZES6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="51"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="318" mass="36518" checksum="778B49E8C1CB70F1" modified="2019-11-13" version="1">MRYIKFLIFLVPFVVLGQADLDKAKKFIADKHYLKAEQLLSKYVAKHETDKKSIELLGDAYGYQKKWDEASEYYKSLVDLEPSNANFQYKYGGALGMKALGISKFSALLIIDDVKTAFLKAAELDPNHIETRWALVELYMQLPGIIGGSKSSSLKYAEELQDLSTVDGYLAKGYIYEYDKSPDLAEKYYKMAIAEGGSFTCYEKLTTLYENEKQPEKAISTMEDAVKTHKRNAMHYQIGKVCAEYNIQLEKGENCLFTYIENHSAKDGVPKAWAYYRLAQIKRYKKDKVKALEFIDMAIVELPKIEPFRKERAQILKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZET9</accession>
    <name>A0A5C6ZET9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="313" mass="35009" checksum="F62965E462BE8F23" modified="2019-11-13" version="1">MKILVTGAVGFIGSHAAERLHSLGHEVIGLDNFNDYYSLDLKNLNAKALTQKGIAIIKKDLRDADLAAFLPKDMDYIFHFAAQPGISQSSTFEDYFSNNILATKNLIDYAEGCAHLKLFVNIGTSSIYGLEATFPEDVASKPASHYGVTKLAAEQLVLQKSREALFHACSLRLYSVIGPRERPEKMYTKLIACALNGEAFPLFEGSDKHLRSFTYVDDIVDGIVSVIGKETKVNGEIINLGTEVEHTTKQGIEAVERILNKKIKLNVIPKRPGDQWRTKANIDKAKRLLDYNPQTSLMRSVEQQVQWFKENFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEY7</accession>
    <name>A0A5C6ZEY7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15635</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="238" mass="27691" checksum="5CC121132539F64C" modified="2019-11-13" version="1">MIDKEQLIADYFLNSLSEKDQKSFDLLMTTDAEFKADLDFQRRVKNAIHKKEHEKLKQHFKEWEGNSESKRSSSSKRIWYIAASIILMLTLGFYFMQAKTAESLYADYYQPAKNIVHPIVRSNDVNDRKNKAFIAYKKKDYLTAHQLFEGLYKTTLDSELLFYDAIALLEIDSTAKAIEQLKSHQNFEDAVSAKTNWYLALAYLKSNDIPQSKQLLKEIVQVEGYNYDKAKKILSALD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFE7</accession>
    <name>A0A5C6ZFE7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_11150</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="86"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="21"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="35"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD88788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="175" mass="19161" checksum="2B7C8582634C4230" modified="2019-11-13" version="1">MKTLLKLFTVLSITVLLSCGGKEDKKKDSSSESNSPKTEKATQTPAAKTETAAKTQEVKPSKRVDLTTKGVGPIKSVTLASTIDQDMAAKGAEVFKNMCTACHRTDKKFIGPAPTGILERRTPEWVMNMILNPEGMVKEDPLARELLIEFNGSPMANQNLTEAEARSVLEYFRTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFE8</accession>
    <name>A0A5C6ZFE8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 7" type="primary">rplB</name>
        <name evidence="7" type="ORF">ESY86_14845</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01320_B">
        <property type="entry name" value="Ribosomal_L2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022666">
        <property type="entry name" value="Rbsml_prot_L2_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002171">
        <property type="entry name" value="Ribosomal_L2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005880">
        <property type="entry name" value="Ribosomal_L2_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022669">
        <property type="entry name" value="Ribosomal_L2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014726">
        <property type="entry name" value="Ribosomal_L2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691">
        <property type="entry name" value="PTHR13691"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00181">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03947">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002158">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01383">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01382">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01171">
        <property type="entry name" value="rplB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L2_C" evidence="6">
        <location>
            <begin position="125"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="224"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD87944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="275" mass="30006" checksum="9B653F7AE7DB129E" modified="2019-11-13" version="1">MSVRKLKPITSAQRFRVVNGFDAITTDKPEKSLLVPNKRSGGRNSQGKMTIRQVGGGHKRRYRIIDFKRNKAGIPAEVKSIEYDPNRTAFIALLNYQDGEKRYIIAQNGLQVGQTVLSDRTGVAPEIGNAMPLSQVPFGSIISCIELRPGQGAVMARSAGAFAQLMARDGKFASIKLPSGETRLILAECMATIGVVSNSDHQLTVSGKAGRSRWLGRRPRVRPVVMNPVDHPMGGGEGKSSGGHPRSRNGVPAKGYRTRSKTKASNKYIVERRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFH1</accession>
    <name>A0A5C6ZFH1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">YbjQ family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0145 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002765">
        <property type="entry name" value="UPF0145"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035439">
        <property type="entry name" value="UPF0145_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34068">
        <property type="entry name" value="PTHR34068"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01906">
        <property type="entry name" value="YbjQ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117782">
        <property type="entry name" value="SSF117782"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="108" mass="11766" checksum="28B4BDF04D2E91DA" modified="2019-11-13" version="1">MILTTTNSIEGFKIAEYKGIVTGVAYDSSYKHKGANLSFKDMFNTSKYYEVYAAGLESIKEKAFQKLRENAKALGANAVVGIRVDIEPLANSYTLIVSITGTAVFVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFM2</accession>
    <name>A0A5C6ZFM2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="11">DEAD/DEAH box helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">ESY86_16335</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Q_MOTIF" evidence="10">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="32"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="217"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="372"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="5">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="382"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD87600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="427" mass="46236" checksum="25E080138DE72A33" modified="2019-11-13" version="1">MSFQSLGLSEALLKAISKKGYNTPSPIQSKAIPPVLEGRDVLASAQTGTGKTAGFVLPMLQILSQKESLRNRPVRALILTPTRELAAQVFANVKEYGEFLDMRSAVIFGGVNQKSQVAKLREGVDVLVATPGRLIDLQNQGLLSLSKIDIFVLDEADRMLDMGFLRDIERIMKLIPSKRQNLMFSATFSKDIKKLAHGILNNPVQVEATPENTTVEAIAQKVYRVAKDKKTGLIIKLIQDGGWDQVLVFTRTKHGANKLCKKMISDGITAAAIHGNKSQGARTKALAGFKSGSVKVLVATDIAARGLDIPLLPHVVNFELPNISEDYVHRIGRTGRAGASGEAISLVSADETTFLRDIEKLVGERIPVEIMEGYEPDPNASTEPIKQGQGGRNRGRSSNSGRNSGGNSRSSGNSRSNSGRNKRSSNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFQ6</accession>
    <name>A0A5C6ZFQ6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Cytochrome c oxidase subunit II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">ESY86_14380</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome c oxidase subunit 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070469">
        <property type="term" value="C:respirasome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045187">
        <property type="entry name" value="CcO_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002429">
        <property type="entry name" value="CcO_II-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011759">
        <property type="entry name" value="Cyt_c_oxidase_su2_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036257">
        <property type="entry name" value="Cyt_c_oxidase_su2_TM_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22888">
        <property type="entry name" value="PTHR22888"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02790">
        <property type="entry name" value="COX2_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81464">
        <property type="entry name" value="SSF81464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50857">
        <property type="entry name" value="COX2_CUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50999">
        <property type="entry name" value="COX2_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="88"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="COX2_TM" evidence="11">
        <location>
            <begin position="65"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="COX2_CUA" evidence="10">
        <location>
            <begin position="164"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TXD88071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="356" mass="40685" checksum="E2015E551EE829F6" modified="2019-11-13" version="1">MTAFLTIIIVLFVAVAIWQMVKIFDLAQIGSADSTQVATDNDNKINGYLMLGFLAFIYITTILCFWYIGDLPLMSNAASEHGSEIDNLMIISMVIIFIVQTVTQFLLYYFTFKYRGEKGRTALYYADNNTLEAIWTFIPVIVLSGLIIYGLFTWTSIMNIDQSDDPLIVELYAQQFNWKARYAGNDNVLGLADVRLIDIDKANILGLDESDPNAQDDIITTVLHLPVGKPVLFKMRSQDVLHSAYMPHFRAQMNCVPGMITQFGFTPTVTTEDMRQRPAIVEKVNNINALRQENSEAVEARGQELFYQFDYLLLCNKICGKSHYNMQMKIIVETQEEYDAWINEQKLFKDSLIKQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFY9</accession>
    <name>A0A5C6ZFY9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">OsmC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003718">
        <property type="entry name" value="OsmC/Ohr_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036102">
        <property type="entry name" value="OsmC/Ohrsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019904">
        <property type="entry name" value="Peroxiredoxin_OsmC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02566">
        <property type="entry name" value="OsmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82784">
        <property type="entry name" value="SSF82784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03562">
        <property type="entry name" value="osmo_induc_OsmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="140" mass="15099" checksum="741802C1AF1AB7DE" modified="2019-11-13" version="1">MKFTRNANAQWKGSGKEGKGHLTTGSKTLDAAPYTFVTRFEDANKGTNPEELIGAAHAGCYAMQLSFLLGEEGFTPNSLDVDAEVSFEDGSITKVMLNLKGDVPKIDAEQFQQIATKAKEVCPVSKLLDTKIELKVALSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG10</accession>
    <name>A0A5C6ZG10_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF2851 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_16195</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021272">
        <property type="entry name" value="DUF2851"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11013">
        <property type="entry name" value="DUF2851"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="423" mass="48776" checksum="CA35323C6C62CEC2" modified="2019-11-13" version="1">MQEDFLHYVWKHKKIDVLNLKTSKQQPIRIVSVGRHNYNSGPDFFNAQLSIGDQLWAGNVEIHIKSSDWYAHHHEQDVAYDNVILHVVYEHDSDIFRKDNSEIPTLELKQVINQGVFENYKRLFSAKHQWINCETDFAAVDDFIISNWLQRLYFERLEVKANRVEALLTASKNDWEAVLFKLLAKSFGLKVNGEAFLSMASSMDFSVIRKTQNKQMALEALFFGQAGLLEHATDVSYQVALQKEYEFLKQKFQLENSHVMPFQFFRLRPPNFPTIRLSQLAMLYHKEQHLLSELIAAKSMADFYELFEVTTSEFWKSHYTFSKCSKASAKKLTKAFVDLLVINTILPIKFSYARHKGQSVVQEISELISEIEAEKNSISKGFNSLKVVASSAMDSQALIQLKTNYCDTNQCLRCAIGNSLLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG76</accession>
    <name>A0A5C6ZG76_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">MoaD/ThiS family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_13305</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003749">
        <property type="entry name" value="ThiS/MoaD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02597">
        <property type="entry name" value="ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="SSF54285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="78" mass="8568" checksum="208D88A2B5527AE7" modified="2019-11-13" version="1">MKVTLKYFGVIAESAGKSEEVLELEQGLSLRELKDQQIKTYQIQDAGSVQIAVNQNLNNEVELKEGDEVAFLPPFAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG90</accession>
    <name>A0A5C6ZG90_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_14085</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046219">
        <property type="entry name" value="DUF6252"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19765">
        <property type="entry name" value="DUF6252"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023115379" evidence="2">
        <location>
            <begin position="19"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="340"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="400" mass="43119" checksum="38C1A06BF18F811F" modified="2019-11-13" version="1">MKKLALLFIIAISLVSCDDTEFNDPAFQGNKDYVLWRADAFSASIDDNGFLTITGSNNVETVNLRVPTVQVGTYVLGEVNAREAQVVTVDGTVYSTNNRPADSISLYPELGFVKIDEISNNTFTGTFEFLVFDESGLNSIGYNEGIFYRVPLVSGNFPTEIVTCEDTEAAVSSTKLAYFDSFSSELAYIDRETFINACQAYGVALNRKLTFCSDADGSVASDIEALNSCAFPCDFALVNRNTAEAAFNAASIGQYVDACANYEFYLQQQKEVCGDANGAIQNAIDALTCGDADADGIPDNFEDFNGNGDLLDDDLDNDGTPNYLDNDDDGDGVLTLYEAKDEDGNPADTDGDGDVNYLDNDDDGDTILTIDENADPNMDGNPEDALDSDGDGIPDYLDAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGG8</accession>
    <name>A0A5C6ZGG8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">SCO family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_11220</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SCO1/2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02968">
        <property type="entry name" value="SCO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045800">
        <property type="entry name" value="HMBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003782">
        <property type="entry name" value="SCO1/SenC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12151">
        <property type="entry name" value="PTHR12151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19335">
        <property type="entry name" value="HMBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02630">
        <property type="entry name" value="SCO1-SenC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022887125" evidence="3">
        <location>
            <begin position="22"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="73"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD88802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="239" mass="26767" checksum="437B48FA8A1B9AD8" modified="2019-11-13" version="1">MKSIKLVITAIIIIATMLSCNSNSSKKGQEEATLYECPMHCEGDKTYDEPGSCPVCKMDLVPVSELETKALVATEISEASIFNLTTQWHTEEDKEIQLKDLKGKTLVMVMIYTSCKAACLRLVADMRAIEEKIPDVRIKDIAFVMVSIDPEVDTPERLKAFAKENYMDDEQWTFLQGTESGVREFANVLSMKYKEISPIDFSHSNIISVFNPGGELVHQQEGLGVNNDETLESIMQLTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGM7</accession>
    <name>A0A5C6ZGM7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Helix-turn-helix transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_09480</name>
        <name evidence="3" type="ORF">ESY86_09505</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="8"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="111" mass="12424" checksum="640140BCBC78DB7A" modified="2019-11-13" version="1">MQSFGKKLRECRDAKKLSQSALAKLLSTNHSIIGKYERDEVKPTIDVVKKLAEALDTNVGYLLGETENSNILKDSSMLKRLNDIASFSKKEQEHILFALDAMITKIKLGSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGM9</accession>
    <name>A0A5C6ZGM9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD(P)/FAD-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="1">
        <location>
            <begin position="6"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="377" mass="41903" checksum="B5B182D792B0C914" modified="2019-11-13" version="1">MQPIATEVLIIGGGLAGLCAAIHLSKAGFEVILIEKNSYPKHKVCGEYVSNEVLPYLEFLGIDVFAEGAKRISKFELTTTNNKTISANLPLGGFGMSRYCLDAILAEKAQENGTRIVQDTVTDIQFEAHNFSVATKTGNTYRSKISIAAFGKRSNLDVTMNREFIQKKSPYLGVKTHIKAEFPEDLVALHNFKGGYCGLSKVESNAINLCYITTFKAFKKHKDIESFQEEVLFKNKALKHIFENSRPVFDVPLTISQISFETKSPVENHILMCGDSAGMIHPLCGNGMGMAIRSAQLASQLIIEYLENRIPSREALEHQYTKQWNANFSQRLSMGHAIAAIFRNDSLAALLLGLLKLCPWMLPKIIKRTHGKPMQVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGP7</accession>
    <name>A0A5C6ZGP7_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Histidine biosynthesis bifunctional protein HisB</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="8">Histidinol-phosphatase</fullName>
                <ecNumber evidence="8">3.1.3.15</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="8">Imidazoleglycerol-phosphate dehydratase</fullName>
                <shortName evidence="8">IGPD</shortName>
                <ecNumber evidence="8">4.2.1.19</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="8 9" type="primary">hisB</name>
        <name evidence="9" type="ORF">ESY86_10455</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + H2O</text>
            <dbReference type="Rhea" id="RHEA:11040"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57766"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="EC" id="4.2.1.19"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>H2O + L-histidinol phosphate = L-histidinol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14465"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57699"/>
            <dbReference type="ChEBI" id="CHEBI:57980"/>
            <dbReference type="EC" id="3.1.3.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 6/9.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 8/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">In the N-terminal section; belongs to the histidinol-phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.15" evidence="8"/>
    <dbReference type="EC" id="4.2.1.19" evidence="8"/>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00011"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004401">
        <property type="term" value="F:histidinol-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004424">
        <property type="term" value="F:imidazoleglycerol-phosphate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07914">
        <property type="entry name" value="IGPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01022">
        <property type="entry name" value="Bifunc_HisB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00076">
        <property type="entry name" value="HisB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006549">
        <property type="entry name" value="HAD-SF_hydro_IIIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020566">
        <property type="entry name" value="His_synth_bifunc_HisB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005954">
        <property type="entry name" value="HisB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006543">
        <property type="entry name" value="Histidinol-phos"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038494">
        <property type="entry name" value="IGPD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000807">
        <property type="entry name" value="ImidazoleglycerolP_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020565">
        <property type="entry name" value="ImidazoleglycerP_deHydtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23133">
        <property type="entry name" value="PTHR23133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00475">
        <property type="entry name" value="IGPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01662">
        <property type="entry name" value="HAD-SF-IIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01261">
        <property type="entry name" value="hisB_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01656">
        <property type="entry name" value="Histidinol-ppas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00954">
        <property type="entry name" value="IGP_DEHYDRATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00955">
        <property type="entry name" value="IGP_DEHYDRATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="8 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 8 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 8" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Histidinol-phosphatase" evidence="8">
        <location>
            <begin position="1"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Imidazoleglycerol-phosphate dehydratase" evidence="8">
        <location>
            <begin position="187"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8">
        <location>
            <position position="8"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="10"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD88911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="377" mass="42889" checksum="FAB9B4B3CCA74A89" modified="2019-11-13" version="1">MKRILFIDRDGTLIKEPADEQIDSFEKLEFYPKVFQYLSRIAKELDFEIVMITNQDGLGTAVYPENTFWPVHNFMLQTFEAEGIVFKEQFIDRTFAKDNAATRKPNTGLLTQYFTADYDLANSFVIGDRLTDIELAKNLGAKGIFINDHTHLGTDEITVKRDALEDFIALESNDWESIYKFLKTDARTGSIIRNTNETKIKIVLNLDGTGKSNIDTGIAFFDHMLDQIARHGQLDLNVDVKGDLEVDEHHTIEDTAIALGEVFASTLGNKLGIERYGFSLPMDDCFAQAAIDFGGRNWLVWEADFKREMIGKMPTEMFYHFFKSFTDGAKCNLNIKAEGNNEHHKIEAIFKAFAKAIKMAVKRDVEKMILPSTKGML</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGS9</accession>
    <name>A0A5C6ZGS9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cytokinin riboside 5'-monophosphate phosphoribohydrolase</fullName>
            <ecNumber evidence="1">3.2.2.n1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LOG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.n1" evidence="1"/>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009691">
        <property type="term" value="P:cytokinin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005269">
        <property type="entry name" value="LOG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031100">
        <property type="entry name" value="LOG_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03641">
        <property type="entry name" value="Lysine_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00730">
        <property type="entry name" value="TIGR00730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0203">Cytokinin biosynthesis</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="229" mass="25609" checksum="3137AA793E1B13FD" modified="2019-11-13" version="1">MRKEQQSKAWNLIKTNDSWAIFKIMGEFVNGYEKLSKIGPCVSIFGSARTKPDHKYYKLAEEVATKIVEHGYGVITGGGPGIMEAGNKGAHIAGGTSVGLNIDLPFEQHDNPYIDSDKSLDFDYFFVRKVMFVKYSQGFVVMPGGFGTLDELFEAITLIQTNKIEKFPIILVGSDFWNGLMDWVKSTLLEANNNVSAKDLELIHVVDTADEIITILDDFYKEYGLSPNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGU9</accession>
    <name>A0A5C6ZGU9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">YpdA family putative bacillithiol disulfide reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ypdA</name>
        <name evidence="1" type="ORF">ESY86_10080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023856">
        <property type="entry name" value="Bacillithiol_biosynth_YpdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04018">
        <property type="entry name" value="Bthiol_YpdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="327" mass="37147" checksum="4B1A13B2C61D1F34" modified="2019-11-13" version="1">MEKQIIIIGAGPIGIACALECKKHGWDYLVLEKGSLTNSLFNYPLNMTFFSTSEKLEIDRIPFISNNPKPSRNEALEYYRRVTTANTLNINLYEKVESIKKHEETFLLKTDKAEYRAHKVIIATGFYDIPNYLNVKGEQLPKVMHYYKEAHPFTLQNVAVVGASNSSVDASLEIYRKGGNVTMIVRGHEIGERVKYWVRPDVINRIEEGSIKAFFNSEIHTIEPHQITVKTPEGLKTIPNDYVIALTGYRPNFDFLKQAGVTFSEDKKHIPTYNDETMETNVDGLYLAGVICGGMETHKWFIENSRIHAKLIAEALEKSPSTLQIKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH56</accession>
    <name>A0A5C6ZH56_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Carbamoyl-phosphate synthase small chain</fullName>
            <ecNumber evidence="2">6.3.5.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Carbamoyl-phosphate synthetase glutamine chain</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 4" type="primary">carA</name>
        <name evidence="4" type="ORF">ESY86_14970</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>2 ATP + H2O + hydrogencarbonate + L-glutamine = 2 ADP + carbamoyl phosphate + 2 H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:18633"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-arginine biosynthesis; carbamoyl phosphate from bicarbonate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 1/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Composed of two chains; the small (or glutamine) chain promotes the hydrolysis of glutamine to ammonia, which is used by the large (or ammonia) chain to synthesize carbamoyl phosphate.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the CarA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.5" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00171"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004088">
        <property type="term" value="F:carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01744">
        <property type="entry name" value="GATase1_CPSase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01209">
        <property type="entry name" value="CPSase_S_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006274">
        <property type="entry name" value="CarbamoylP_synth_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002474">
        <property type="entry name" value="CarbamoylP_synth_ssu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036480">
        <property type="entry name" value="CarbP_synth_ssu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035686">
        <property type="entry name" value="CPSase_GATase1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00988">
        <property type="entry name" value="CPSase_sm_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01097">
        <property type="entry name" value="CPSase_sm_chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52021">
        <property type="entry name" value="SSF52021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01368">
        <property type="entry name" value="CPSaseIIsmall"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="2 4" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CPSase_sm_chain" evidence="3">
        <location>
            <begin position="7"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="CPSase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="257"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="343"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD87969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="367" mass="40853" checksum="D32D27A4EA79F2D8" modified="2019-11-13" version="1">MSYLKRKKALILLADGTIFYGKAVGKEGSAFGEVCFNTGTTGYQEIFTDPSYFGQLMVTTNAHIGNYGTLTEESQSKSIKIAGLICRNFSYEYSRAAGDDSLENYFIKQDILAISNVDTRALVGYIRDHGAMNAVITTEVDNLEALKKELAEFPNMDGLELASKVSTKDPYYFGNETAKYRVSALDLGIKTNILRNMANRDIYVKVFPYDATFEEMQAFNPDGYFLSNGPGDPEPLKDAQKLAKKIIELNLPLFGICLGHQVIAQANGISTYKMHNGHRGINHPVKNLITGKGEITSQNHGFAINREEAENHPDFEITHIHLNDQTVAGMKMKHKNCYSVQYHPEASPGPNDASYLFDAFIENIQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH73</accession>
    <name>A0A5C6ZH73_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="167" mass="19115" checksum="B0B69D114AF54117" modified="2019-11-13" version="1">MKLYHAKAPDNFQKQLQTFKALLKGSMMAKTSSFMLIAVSLVLAYKSRDNMLNVLLLLTGMASVVFYIIKHLSLQEIKQKSYTQRSLMSSISKFKAYMANRKKYEIYFLGFWIISLIPYATSFLDSKLHAILFAILYIAVVTVLGNLAYKKIDKIIAHLESELQSIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH88</accession>
    <name>A0A5C6ZH88_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="15"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="345" mass="38970" checksum="48EEBF2A460CEFC6" modified="2019-11-13" version="1">MIYTNLPNTNIKVSKLCLGTMTWGNQNTQDDGFAQMDLALDRGVNFFDTAELYPVPAGARTYADTERIIGNWFQKTGQRDKVVLASKIAGTGDYTAHIRTKGFCKETLEDAVNQSLKRLKTDYIDLFQLHWPERNANYFGVRDYKIDAEERWQDNFNEILQVFDGIIKSGKIREIGISNEKAWGTMRYLEEAKTHGLPKMITIQNPYSLLNRTFEGDLAEISYRENIGLLAYSPLACGVLTGKYIQGKDTKDSRLNLFERFSRYSSQNCTEATKCYLKIAEDHNLSMTQMALAFVNQQAFLTSNIIGATSAAQLSENIDSIDIHLNEEILGAINEVHEAQPNPAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHL8</accession>
    <name>A0A5C6ZHL8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Imidazole glycerol phosphate synthase subunit HisF</fullName>
            <ecNumber evidence="9">4.3.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">IGP synthase cyclase subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">IGP synthase subunit HisF</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">ImGP synthase subunit HisF</fullName>
            <shortName evidence="9">IGPS subunit HisF</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 11" type="primary">hisF</name>
        <name evidence="11" type="ORF">ESY86_10475</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 9">IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + L-glutamine = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + H(+) + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24793"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="ChEBI" id="CHEBI:58525"/>
            <dbReference type="EC" id="4.3.2.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 5/9.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 9">Heterodimer of HisH and HisF.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9 10">Belongs to the HisA/HisF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.10" evidence="9"/>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000107">
        <property type="term" value="F:imidazoleglycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04731">
        <property type="entry name" value="HisF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01013">
        <property type="entry name" value="HisF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006062">
        <property type="entry name" value="His_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004651">
        <property type="entry name" value="HisF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00977">
        <property type="entry name" value="His_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00735">
        <property type="entry name" value="hisF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9 10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9 10" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="7 9 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="9">
        <location>
            <position position="11"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD88914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="251" mass="26788" checksum="7BF7929452BE3460" modified="2019-11-13" version="1">MLTKRIIPCLDIKNGRTVKGVNFVDLRDAGDPVELAKQYAELGADELVFLDISATLEGRKTMIDMVLKVAEHVNIPFTVGGGISSVEDVDVLLKSGADKVSINSSAVKRPELVTELANKFGSQCVVVAIDAKQINGEWLVHLAGGTVPTDLNLFDWAKEVEERGAGEILFTSMNNDGTKAGFANEALAKLSETLNIPIIASGGAGSVQHFVDSFKIGKADAALAASVFHFGEIEILDLKQELRANGIAIRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHQ9</accession>
    <name>A0A5C6ZHQ9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Arylesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_10705</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGNH_hydro" evidence="2">
        <location>
            <begin position="69"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="248" mass="26966" checksum="DBAE1FC0694F8757" modified="2019-11-13" version="1">MSKAQNNQLYLNPPASLLRKILKFCYFIPLVLVLACGTDKKEKTNQEESAKAKTEQTETTNNSSKTILAFGDSITAGYGLADTADAFPGVLQQKIDALNLNYTVINSGLSGETTAGGKSRIAWVLNQDIDIFLLELGANDGLRGVPLSETRANLQAIIDIVQEKSPETTIILAGMELPPNMGQDYTTEFKQLYADLAKKNDLEFIPFILKDVGGIAALNQSDGIHPTAEGHKILANTVWEVLEPVLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHS9</accession>
    <name>A0A5C6ZHS9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF2064 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_09180</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018641">
        <property type="entry name" value="Trfase_1_rSAM/selenodom_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36529">
        <property type="entry name" value="PTHR36529"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09837">
        <property type="entry name" value="DUF2064"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="228" mass="25748" checksum="B98CA0E21417C4BF" modified="2019-11-13" version="1">MNTNNTAILIFANSAQQEAFAKPFESSALLFDALNRDILKKVERTGLPYYHVSEKEQIGNSFAQRFTNAIQSIYTKGYDRVITVGNDTPHLNSGQILKAAQQLETNDIVLGPSLDGGFYLMGLKKSHFNAKTFLKLPWQTAGLSQSMYRLIAANKTKLFTLETLVDIDSISDVNRILQSKRHISTLLRQLLLAVFSEKNTSFFRYQLSFQNSFLSLYYNKGSPLPLFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHY5</accession>
    <name>A0A5C6ZHY5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Acetate--CoA ligase</fullName>
            <ecNumber evidence="8">6.2.1.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">acs</name>
        <name evidence="8" type="ORF">ESY86_11115</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.1" evidence="8"/>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003987">
        <property type="term" value="F:acetate-CoA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016208">
        <property type="term" value="F:AMP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019427">
        <property type="term" value="P:acetyl-CoA biosynthetic process from acetate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011904">
        <property type="entry name" value="Ac_CoA_lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032387">
        <property type="entry name" value="ACAS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16177">
        <property type="entry name" value="ACAS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02188">
        <property type="entry name" value="Ac_CoA_lig_AcsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0007">Acetylation</keyword>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACAS_N" evidence="7">
        <location>
            <begin position="12"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding" evidence="5">
        <location>
            <begin position="71"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="6">
        <location>
            <begin position="519"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD88781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="636" mass="71669" checksum="19C8C6E86F3F2E35" modified="2019-11-13" version="1">MSHYHIKHLEEYYQVYRKSVRNPEIFWEEIAEEHFLWRKKWDKVLDWNFETPEIKWFEGAQLNITENCIDRHLATRGNKTALLFEPNDPTEAAQHITFQELSERVNKMANVLKAKGVTKGDRVCIYLPMIPELAVSVLACARIGAIHSVVFAGFSANALASRINDSDCKLVVTSDGSFRGEKTIDLKGIVDNALEDCPGIEAVLVVNRIASEVQMKDGMDHWLQPLLDEASAECQAEVMAAEDPLFILYTSGSTGKPKGIVHTTAGYMVYTAYTFKNIFQYRENDVFWCTADIGWITGHSYIVYGPLCNGATTVMFEGVPSYPDYGRFWDIVEKHKVTQFYTAPTAIRALAKEGVAHLQNRDLSSIKVLGSVGEPINEEAWHWYDDNVGKRKAPIVDTWWQTETGGIMISPIPFVTPTKPTYATLPFIGIQPALMDEQGEEIKGNQVDGRLCIKFPWPGMLRTIWRNHERFKDTYFSAYKGMYFTGDGALRDEVGYYRITGRVDDVIIVSGHNLGTAPIEDAINEHPAVSESAIVGFPHDIKGNALYGYVTLKDSGESRDHNNLRKEINQIITEQIGPIAKLEKIQFTNALPKTRSGKIMRRILRKIAQGEFDDLGDTSTLLNPEVVEEISKNAIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI92</accession>
    <name>A0A5C6ZI92_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Imelysin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_06620</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14659">
        <property type="entry name" value="Imelysin-like_IPPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018976">
        <property type="entry name" value="Imelysin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034984">
        <property type="entry name" value="Imelysin-like_IPPA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038352">
        <property type="entry name" value="Imelysin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09375">
        <property type="entry name" value="Peptidase_M75"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Peptidase_M75" evidence="2">
        <location>
            <begin position="47"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="372" mass="41028" checksum="F13D19F90E5034C8" modified="2019-11-13" version="1">MIRKSLLAFFTLSLLLGCSSSDEGDSGSQNDGFDRQVMLSNWADNIIIPAYQDLNADLMDLSAQKEAFVNSPNQANLETLRASWLSAYKTWQYLEMFTSGKAEETNYVFQMNVYPTNVDDIEANIASGNYDLSNPNNNDAVGFPALDYLLFGLAETDAQILNAYTSNTKAEANKTYLSDVVNQMQSLTATVLNDWTGTYRDAFVNSTGNTATSATNKMTNDFIFYYEKGLRANKIGIPAGVFSAAPLSSKVEAFYNEEISKTLALEGLNAVQDFFNGKAYNSNATSGSFKAYLEYLNTINNGEDVSALINSQFNAARTKIESLDNNFVQQVETDNTQMTEAFDALQKVVVLLKIDMVQAMSIRLDYADSDGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIC9</accession>
    <name>A0A5C6ZIC9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="384"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="385"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="543" mass="60436" checksum="85C4F945F790CBF3" modified="2019-11-13" version="1">MKSKFIPLAIALVGILCFATSFIIPSSNSGELEVEIEKSAFIMPAVHRVYSNPDALNGKYHLFKAKITNKSNQTLEDVTVKYRIPDYIDWTELTVSGQMFPGQTLVIPCYPKFKDDITEKSTESIEKAQIEISWDGAEEDDIIEEEFSFKITNRNEYVYTGVKTEEISTWSDMYDNDALIACFVTPNDPVVKYYTQNLQEKMMKGEAASITRKPEDGVRFLANIYEATRKSHMVYSGTKGIPQSTEDIQSIVQQIRLPREVITGNTGLCIELSCLYASVLSAAGLDPIIYMVPGHAYPGFKMNGQYFAIEATSINGQGLGGIASAEEAFKKGNENLKEFMERAQSGDPRYTLVDIHAVNQQGVTAMDLKDNDFMRKKVDDIVASWSSEQPVQPKNETQPNRRPSNTEIIVPENSIKTSALSFAIPNGWQTMMRPVPQVPILTAQVVAPDQLTTVSIYDIPAASIEEAMQTIDQYMLNFGMQMQYQSNGNTISGQTQAQDGSTFNWVGKCLKSQNGIRVVAVGAPSYAYNQKTGIINQVFNSIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZID4</accession>
    <name>A0A5C6ZID4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06905</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="209"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="314" mass="36286" checksum="A2BA1814A8F92486" modified="2019-11-13" version="1">MEHPLSHSNLSQMSPFDYSVRSKVQSYNISHNIVLMELCFDAEEQCELKLNEQGQECMYFVYNLESSLLISFENGEKSSLKPFQSAVLYDKNTRTARLQFQSGDAHNLCLLKMIKSKHPEKNGLYHQLEQSFKGLNKQQRFVYIGAANLQICDYIRKLLKLDKESLSNNLMAASYIYMVMSLKLGDYMEALKKPKVVSMLSLKELQHIQKLSDQIIEAPENQYTIEDLCMSSGLTVAKLQQGFKDMHNRTVANFITYIRLVKAEELIKTTDLNISEIVYSIGWTSRSYFCKIFKRHFKCTPKSYKQKIKVAVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZID6</accession>
    <name>A0A5C6ZID6_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="11 12">ATP synthase subunit a</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">ATP synthase F0 sector subunit a</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">F-ATPase subunit 6</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11 14" type="primary">atpB</name>
        <name evidence="14" type="ORF">ESY86_07765</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11 12">Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11 12">Cell membrane</location>
            <topology evidence="11 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11 12">Belongs to the ATPase A chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045263">
        <property type="term" value="C:proton-transporting ATP synthase complex, coupling factor F(o)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01393">
        <property type="entry name" value="ATP_synth_a_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000568">
        <property type="entry name" value="ATP_synth_F0_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045083">
        <property type="entry name" value="ATP_synth_F0_asu_bact/mt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035908">
        <property type="entry name" value="F0_ATP_A_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11410">
        <property type="entry name" value="PTHR11410"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00119">
        <property type="entry name" value="ATP-synt_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00123">
        <property type="entry name" value="ATPASEA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81336">
        <property type="entry name" value="SSF81336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01131">
        <property type="entry name" value="ATP_synt_6_or_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 11 12" id="KW-0138">CF(0)</keyword>
    <keyword evidence="6 11 12" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8 11 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0732">Signal</keyword>
    <keyword evidence="5 11 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11 12" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="13">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022809920" description="ATP synthase subunit a" evidence="13">
        <location>
            <begin position="26"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="149"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="233"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="263"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="294"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TXD89670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="390" mass="43734" checksum="5620F5A3DC28229D" modified="2019-11-13" version="1">MGIFQYRFRFLFLVSFLLCGSALFAQDAEQAEGIVDTKKEVDDYIQHHIQDSHDFTIFSYSNDAGERKHFGFPLPVIVWTSEGLVTFMSSQFDHNDNGEVIVEEEGLSFAKIHGSIYELEGGATAVNLDEEQHATNGDKVIDFSITKSVVGILLIGLLMFVWFFGLARQYKNKKIPTGFGRVLEPLVLYVRDELARPNIGEKHYRKFTGYLLTVFFFIWLLNMAGLTPLGFNVTGQIAVTAALAIFTLIIYTISGNRDYWMHILWMPGVPILIRPILAIIELVGAFIIKPFSLMVRLFANITAGHIVMMSLIAIMFVLRAELGVVGSSVLSVALSLLLFFIELLVAFLQAYIFTMLSALFIGMAVAEHDHDHDKKGHDGSDVEDVRGDFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIF6</accession>
    <name>A0A5C6ZIF6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Pirin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_12045</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the pirin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012093">
        <property type="entry name" value="Pirin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003829">
        <property type="entry name" value="Pirin_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041602">
        <property type="entry name" value="Quercetinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43212">
        <property type="entry name" value="PTHR43212"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02678">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17954">
        <property type="entry name" value="Pirin_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006232">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pirin" evidence="3">
        <location>
            <begin position="13"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="Pirin_C_2" evidence="4">
        <location>
            <begin position="156"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD88691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="239" mass="26578" checksum="39FD2F2D735B3ECC" modified="2019-11-13" version="1">MKTVIHKAADRGQANHGWLQANHSFSFANYFDKDKMSFGALRVLNDDIIAAKMGFGTHPHDNMEIITIPLSGSLKHRDTMKDAWQAIEAGEVQIMSAGTGVSHSEMNGSNDEHLNLFQIWIMPNKRNVEPRYGQKRFDASARRDKLQTVVSSIDSPVDGSLHIHQNAKISRLDLSKGKTFDYTVGGKTQGVYIMTIHGTVSIGTDELQQRDAIGVSETDSFIINSKEDSELLLIEVPMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIJ3</accession>
    <name>A0A5C6ZIJ3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_10955</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD89000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046037">
        <property type="entry name" value="DUF5995"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19458">
        <property type="entry name" value="DUF5995"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="251" mass="28474" checksum="556DC3A098996CFA" modified="2019-11-13" version="1">MPGATTIKNVIEELDAIINESIKTNSRMGLFAYIYKRTTAEVAAEIALGHFKDNQNLERLDVAFANLYLDAYRDYKSHQQVSASWAFAFDQVHEPLTIVQHIMLGMNVHINLDLAVATANTMSGREILDIEEDFNKVNDILLQITNELQDRLSRVSPLMFILDVLGENKDEKIIDFSMRKARGQSWNASNLLWSLGENKSGQAINSIDQLVLKLGKCIKTPKTRTVRFFLRVIQKFETKQVGSIISKLRAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIS6</accession>
    <name>A0A5C6ZIS6_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Probable inorganic carbon transporter subunit DabA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">dabA</name>
        <name evidence="8" type="ORF">ESY86_05110</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Part of an energy-coupled inorganic carbon pump.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="6">Forms a complex with DabB.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the inorganic carbon transporter (TC 9.A.2) DabA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01871">
        <property type="entry name" value="DabA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018752">
        <property type="entry name" value="DabA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38344">
        <property type="entry name" value="PTHR38344"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10070">
        <property type="entry name" value="MpsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6" id="KW-0813">Transport</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="568"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="293"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="295"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="474"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="489"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD90128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="796" mass="89108" checksum="35143DA645B84F82" modified="2019-11-13" version="1">MNQVILNSINEASKVIGKTWPLYTFVASNPLSGYEDASFEEAVSSAQKHFNANAFPAARLYRQAWEKGDIDKKVMISLLKANGLSETPEVYLKLLESQKSTEELNGNHAVDRIMAKWLSAFLDEGLAEWDMPYRSEGFYTAWRLLVIYDSEMGTNSLKEIPKTSAETLEQLLKDYPETDYTKLFTHHLAALPGWTGYINHRTQSNSDWQKDFPIDLMDYLAARLWTAHKLNVPILPEKTEDIPNDLIPKLQHLWLQAWEQSWQNQLVKTLENGAISTASKNAAALPDAQMVFCIDTRSELIRRHVESKGNYETFGYAGFFGIAMDYQSLNDGITRKSCPPILASAYTVSETAQADKKAQFLAYGTKNELIKFADYFLKRMKNMLPSAFGYVEGSGFYYGLSLMARTLAPGLIYRKNQKNASHMEATCQPNINRALQEKTDAPGIPLEEKVGIVKSAFDLMGWKQFAPLVLFVGHGSHSANNPFSSSLDCGACAASPGRHNARMLAKLANLPEVRDALAKTHDILIPEATLFLGAEHNTTTDDIVLFDSEAPESHGQLIKNLKSNLSKAQQTATQNRLGSKGNSVSTAQQKANDWGETRPEWGLSQNAGFIVAPRHLTKHTNLDSRCFLHSYDWELDISGTSLEGIMQGPMVVTQWINNHYYFSTVDNSIFGGGSKITHNITGKFGVVQGNGGDLKMGLPLQSLYLSDDAMYHQPLRLSVMIQAPISRVSKILARNSSLKTLLDNEWIYLMVMDPKQNNEIYRYKKSIQWISTSENKVETNLVKIDISELATTEITM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIU4</accession>
    <name>A0A5C6ZIU4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07785</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="441"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="442"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="843" mass="97242" checksum="43644BAF1845CA85" modified="2019-11-13" version="1">MLSFCCVAILLASCSRKKDTFINRNFHAMGTYYNILYNGNIALENGRETVDNAATDNYWELLPIERMQVKEDAFMPGQAKNQDFERAEEKAIKAVQKHGMNIKGKEFNPQIDEAYLLLGKSRYFDQRFVPALEAFNYILYKYPASDKINTAKVWREKTNIRLENNALAIQNLKELIEDEVLEDQDMADANAILAQAYINTKSKDSALTKLVIAAEFTKKNREQARFNYIIGQLYNEFGKIDSANIAFDKIIDMHRKIPRPYYINAHLAKAANFDTIGGDRMAFEEYLADLEEDRENRPFLDKIFYRIAEYHRGNKHDSLAVAYYNKSLRTNLGDKELRSRDYETLGNMNFDIAEYKLAGAYYDSTMTNLTINSKPFRVIERKRENLEDVIRYEDIARANDSILNLVSLSEADQLAFFTEHTNELKAIAAAEAEKAEAEVRRNTGLQSASNTIQTARIEPSTRGGAPGKQTFYFYNPTTVAYGKNEFVKIWGDRELKDNWRLSDTKSSTFQAIEEQEITTNASEDKRFDPEFYIAQIPSDQKVLDSLARERNFAYYQLGAIYKEKFSEYQLARERLEQLLKNDPEERLILPSKYNLYKIYMELGLAQKAEMTKTDIINNYPDSRYAQILLNPNSGLDQDENSPERLYDGLYKKFGDQDYEEVIAKTEEYINRFAGDPMVPKFEILKASAKGRLFGFEAYKTGVNYIALTYPNTEEGKKADEILKTAIPILAMKEFKPNDEAKHFNVLYPFSSDEKENIPEFIKKLEEAVAKVDYFDLTTSIDVYDQNTIFVVVHGLTSAQGASGFAELLKENKQKIKRQFCAISSPNYEIVQRHKNLSNYLEFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ36</accession>
    <name>A0A5C6ZJ36_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06915</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036629">
        <property type="entry name" value="YjbJ_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69047">
        <property type="entry name" value="SSF69047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="16"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="72"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="94" mass="11489" checksum="DC75469E0B135011" modified="2019-11-13" version="1">MDNQNQKHKDRKDHKKNNQKQNQEANRDLESRWNEIESNYRRRHPNVTDEDVDYEKGEFDSMTNRVAKSTNRSRDQINEDIGNWHLENDKNNNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ69</accession>
    <name>A0A5C6ZJ69_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Aldose 1-epimerase</fullName>
            <ecNumber evidence="4">5.1.3.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_06320</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>alpha-D-glucose = beta-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:10264"/>
            <dbReference type="ChEBI" id="CHEBI:15903"/>
            <dbReference type="ChEBI" id="CHEBI:17925"/>
            <dbReference type="EC" id="5.1.3.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 4">Carbohydrate metabolism; hexose metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the aldose epimerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.3" evidence="4"/>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00242"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004034">
        <property type="term" value="F:aldose 1-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019318">
        <property type="term" value="P:hexose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015443">
        <property type="entry name" value="Aldose_1-epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008183">
        <property type="entry name" value="Aldose_1/G6P_1-epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01263">
        <property type="entry name" value="Aldose_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005096">
        <property type="entry name" value="GALM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="171"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="171"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="292"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR005096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR005096-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR005096-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR005096-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD89816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="331" mass="37202" checksum="0B5903CC5CDA72AB" modified="2019-11-13" version="1">MSTLKTAIITNRNGMELHVSNFGASILSLKVPNKNDGLTEVVVGLSSPLDYLKEDYLEQNRCLGSSIGRYAGRISKGGFTIDDTFYELSQRNGHHLHGGFKGFDKRYWHFEEVIRDENPMMTLTYHSEDGEEGYPGNLQVSVSYQLTETNALIITYKATTDQPTHVNLTSHAYFNLNGEGSVLEHQLQVQSDRYLEVDEHTIPTGKELYSLETNRSRMELSKLGRDDFSGYDDTFILTAEEASTTLISEETGIKMTVGTNQPVLVIFTPKAFSNLSFKEGLTYTDYPAICFEAQNYPDAPNNIHFPSSLLLPSETYENRTVFGFTLEGSEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJC2</accession>
    <name>A0A5C6ZJC2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Peptidyl-prolyl cis-trans isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_06560</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="271" mass="31867" checksum="FA91D01F4A625E85" modified="2019-11-13" version="1">MNSSCDFFKDPTDDQPIARVNEAYLYKRDLEGLVKEGTSKDDSTVIVNNFITKWATQLLLLDGAERNLPEARQIEFDKLVKQYKSDLYSKSYLEALVNRSVDTVINDAEAQLVYETNLATFKLNEDLVKFRYLVLNEKASNNDEIEERFKRFDAEDKNYLDSISIQFKDYWLKDSLWVKKTQMVDRIPVLNAENKSELLKKTNYIQLKDSLNLYLMQIKDVLSQNDLAPLEYVRPTIKQIVVNKRKLELIKTFEKDITKDAIKNKRFEIYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJE1</accession>
    <name>A0A5C6ZJE1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">VOC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_04755</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="6"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="128" mass="14269" checksum="D0E988CB99F32644" modified="2019-11-13" version="1">MASQNPIVWFEIYVKNMKRAQTFYEEVFDVKLSELPTPDTLDGPMQMMAFPSEMDGPGAAGVLVKMEGFEAGNNSTLVYFRSDDCQEQKRIEKAGGTVCQTKQSLGEHGFMVLAKDTEGNMFGIHSMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJG0</accession>
    <name>A0A5C6ZJG0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Tyrosine-type recombinase/integrase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_09495</name>
        <name evidence="8" type="ORF">ESY86_09520</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004107">
        <property type="entry name" value="Integrase_SAM-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02899">
        <property type="entry name" value="Phage_int_SAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="6">
        <location>
            <begin position="34"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="5">
        <location>
            <begin position="135"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="249"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD89265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD89270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="327" mass="38562" checksum="693841DA60350E18" modified="2019-11-13" version="1">MAIKLGKTKDSRTRKKKVTEDAELELLQRLQNEKDQPEFIKYLLQKGYSIKSSERYLKDIERYKKWLNKENITEAAASYNDITHYIQSKKGTVKQITIQTVLASLKQYYNYLQELGFVAENPTVNVQIKGIKRKVLHNILTKQELEKIYFDYKNLESESLSKKRNEIIVSLLVYQGLNTNDIQNLVIKDVKLREGKIFIKGSRRSNERTLKLEAHQILDFMEYQLKTRETILQETNKQTDLFFVTQGSSLKLQNVMQKLMQQLHKQNKQVESVKQIRASVITGWLKVYNLREVQYFAGHRYVSSTENYLINDLEDLKEDINKYHPIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJH6</accession>
    <name>A0A5C6ZJH6_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Site-specific DNA-methyltransferase (adenine-specific)</fullName>
            <ecNumber evidence="2">2.1.1.72</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_06840</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:15197"/>
            <dbReference type="Rhea" id="RHEA-COMP:12418"/>
            <dbReference type="Rhea" id="RHEA-COMP:12419"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90615"/>
            <dbReference type="ChEBI" id="CHEBI:90616"/>
            <dbReference type="EC" id="2.1.1.72"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.72" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011639">
        <property type="entry name" value="RM_methylase_Eco57I-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002686">
        <property type="entry name" value="Transposase_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036515">
        <property type="entry name" value="Transposase_17_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07669">
        <property type="entry name" value="Eco57I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01797">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01321">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143422">
        <property type="entry name" value="SSF143422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Y1_Tnp" evidence="4">
        <location>
            <begin position="616"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="683"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="686"/>
            <end position="795"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD89909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="992" mass="114326" checksum="483F891CC971FE8E" modified="2019-11-13" version="1">MALFQASVLKSHLALLDQSAVDRAYKKYQNYFWNANIQDNIKSAKEEQYQASFLHELFVNILGYTLFPNPDSNLTTEFKNEKNSRKADAAILKDGVAIGVIELKGTITKDLESIRLQAFDYKANQKGCVYVITSNFEKLRFYINDATEFEEFDLFTLSQNRFKLLYLCLHIDKLLNNTALKIKEASIVEEEEITKAFYKDYSVFKRELYRDLVKNNAKTVKAKLIEQERAEDQNDIVQLEKNVKLTLFKKSQKLIDRFLFIFFAEDRTLLPSNSTKQILNKWKHDWDFGDERPLYSLFKQYFLYLDQGRKSTPSRAEIYAYNGGLFKPDAILDALEINNDLLFKHTSKLSNYDFESEVDANILRHIFENALNEIESVNAEIEGGDFDQQTIKRKKDAVFYTPKYITKYIVENTVGKLCVEKKIAIGFKEADYFEVKKGTHQSTKMQLLETLDAYREWLLQLTICDPACSSGAFLNQALDFLIKEHQYIDELKTKVLVGGLQFPDIENTILENNIYGVDFNEESVEITKLSLWLRTAKPRRKLNDLSNNIKCGNSLIDSKTVAGNKAFNWSEEFPQVFKTKDLKAYHITTAVHDSRTSDRMVKYEVRKKRDLGTNPYPNVVYFTDADDLIISQTIAQIVKEDGLRLLAYNICGDHIHLLLVCDIADIPRIMQKIKSVTSKILTREKTQAQGTREHAPLAEETGRETREHAPLAEEEGKTREHAPLAEEEGTREHAPLAEEEGETREHAPLAEEERTREHAPLAEEEGTREHAPLAEETGKKREHAPLAKEKAKKPLWGQKYSVPKEITSTQQLDNTLNYIQKNRSKHELPEHSAQLQTVIDGMLTSKADAFKTEITGGFDVVIGNPPYVRKQGLMEHYPETCVFYEKRYKSATANYDIYALFMERCYDLINRKGIVSFILPHKFLVSDFGAGIRQFFKEKTAVKNLIHFGSEIIFSEASTYNCIIDLTKSRKEKIQFKNLNQKIYLSLLFGTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJI2</accession>
    <name>A0A5C6ZJI2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type II toxin-antitoxin system RelE/ParE family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_07100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009241">
        <property type="entry name" value="HigB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05973">
        <property type="entry name" value="Gp49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="112" mass="13456" checksum="FF0D49817C661304" modified="2019-11-13" version="1">MNPKFKVELLEEVNEFLNGLNEKAREKIIYNMLKAQVVSDNELFKKLNNNVWEFRTLHNKTKYRLFAFWDKTDKTETVVISTHGIEKKTAKTPKKEIEKTERIMKQYFEAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJJ3</accession>
    <name>A0A5C6ZJJ3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type 1 glutamine amidotransferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06880</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DJ-1_PfpI" evidence="1">
        <location>
            <begin position="25"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="226" mass="24847" checksum="40D34BEF92F3927C" modified="2019-11-13" version="1">MVMTSHQDLMNTDSKTGLWIGEFADPYYEFIDQGYEIVLASPLGGKPPIDPLSKLTENITASNRRFTEDEVAKKALSETRLLEEVEASEFDAVFFPGGHGPLFDLANSDICGQLILDFYKQKKPIAAVCHGPAALIKAVELEPAILKGKRVTGFSDAEEKLVFRENNIPFTVENRLVWLGGDYHNAVIPFSSHVEQDGLLITGQNPLSAVPAAKTLIELLEARTDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJQ9</accession>
    <name>A0A5C6ZJQ9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="15 16">Multifunctional fusion protein</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="16">3-hydroxyacyl-[acyl-carrier-protein] dehydratase FabZ</fullName>
                <ecNumber evidence="16">4.2.1.59</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="16">(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="16">Beta-hydroxyacyl-ACP dehydratase</fullName>
                <shortName evidence="16">(3R)-hydroxymyristoyl-ACP dehydrase</shortName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="15">UDP-3-O-acyl-N-acetylglucosamine deacetylase</fullName>
                <shortName evidence="15">UDP-3-O-acyl-GlcNAc deacetylase</shortName>
                <ecNumber evidence="15">3.5.1.108</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="15">UDP-3-O-[R-3-hydroxymyristoyl]-N-acetylglucosamine deacetylase</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="16" type="primary">fabZ</name>
        <name evidence="15" type="synonym">lpxC</name>
        <name evidence="17" type="ORF">ESY86_10390</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 15">Catalyzes the hydrolysis of UDP-3-O-myristoyl-N-acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis.</text>
    </comment>
    <comment type="function">
        <text evidence="14 16">Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>a (3R)-hydroxyacyl-[ACP] = a (2E)-enoyl-[ACP] + H2O</text>
            <dbReference type="Rhea" id="RHEA:13097"/>
            <dbReference type="Rhea" id="RHEA-COMP:9925"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:78784"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="EC" id="4.2.1.59"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 15">
            <text>a UDP-3-O-[(3R)-3-hydroxyacyl]-N-acetyl-alpha-D-glucosamine + H2O = a UDP-3-O-[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + acetate</text>
            <dbReference type="Rhea" id="RHEA:67816"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:137740"/>
            <dbReference type="ChEBI" id="CHEBI:173225"/>
            <dbReference type="EC" id="3.5.1.108"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 15">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 15">Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 2/6.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 16">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the LpxC family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="16">Belongs to the thioester dehydratase family. FabZ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.59" evidence="16"/>
    <dbReference type="EC" id="3.5.1.108" evidence="15"/>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00359">
        <property type="reaction ID" value="UER00478"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008659">
        <property type="term" value="F:(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008693">
        <property type="term" value="F:3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047451">
        <property type="term" value="F:3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004317">
        <property type="term" value="F:3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008759">
        <property type="term" value="F:UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103117">
        <property type="term" value="F:UDP-3-O-acyl-N-acetylglucosamine deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1700.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00406">
        <property type="entry name" value="FabZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00388">
        <property type="entry name" value="LpxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013114">
        <property type="entry name" value="FabA_FabZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010084">
        <property type="entry name" value="FabZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004463">
        <property type="entry name" value="UDP-acyl_GlcNac_deAcase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011334">
        <property type="entry name" value="UDP-acyl_GlcNac_deAcase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015870">
        <property type="entry name" value="UDP-acyl_N-AcGlcN_deAcase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33694">
        <property type="entry name" value="PTHR33694"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07977">
        <property type="entry name" value="FabA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03331">
        <property type="entry name" value="LpxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01750">
        <property type="entry name" value="fabZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00325">
        <property type="entry name" value="lpxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 16" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 15" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="6 15" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11 15" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12 16" id="KW-0456">Lyase</keyword>
    <keyword evidence="8 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 15" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton donor" evidence="15">
        <location>
            <position position="293"/>
        </location>
    </feature>
    <feature type="active site" evidence="16">
        <location>
            <position position="371"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="266"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00024535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00025049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="TXD88899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="468" mass="51839" checksum="E7CCACB3A471CE6C" modified="2019-11-13" version="1">MAIIKTDVKQKTIKEKISLTGVGLHTGKNVTLTFCPAPSNTGFCFKRTDLEGSPVIEADANYVTNTERGTCLEKNGVTIQTSEHVLAALVGMDLDNIIVELDASEPPIMDGSAKFFIEALEKAGLENQDEFREEYVVTEVISFCDEVSGSEIIVMPAKNYQVTTMVDFGTKVLGTQNATMNHISEFKTEISDSRTFSFLHELETLLEHGLIKGGDLNNAIVYVDKELSPKTMEKLKIAFKKDSIAIKPNGILDNLTLHYPNEAARHKLLDVVGDLALVGTRIKGKVIANKPGHNINTLFAKKLSKIIKNEKRNNVPYVDLNQEPLMDVNKIMEMLPHRQPFLLLDKVFELTDTGVIGMKNVTMNEEFFKGHFPGAPVMPGVLIIEAMAQTGGILVLSTVPDPENYLTFFMKIDKVKFKQKVVPGDTLIFKCDLITPIRRGICHMQGYAYANGKLCAEAELMAQISKVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJT3</accession>
    <name>A0A5C6ZJT3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF255 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_07330</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="155" mass="18318" checksum="DACB7D8793683418" modified="2019-11-13" version="1">MWRIIIIILIVFTSTAFAQHEEKVNWLSFEQLNDSLKVKPKKVFIDFYADWCAPCLRMQREVFTDETIVKILSNDYYAVKMNVESTDTISFGNQQFINKRAKRRNPVHQIPKLMASQKNKPFSLPALVFMDENFQVTGRYFQYLNVSQLKEILLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJX5</accession>
    <name>A0A5C6ZJX5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05115</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="174" mass="19446" checksum="FB255AF77E22D47F" modified="2019-11-13" version="1">MKNFNFAQKLILVTILLLCASLLFLYWYKHTYTLDVPNDEEVNSTALDGKLLIAAMGSPFKDSIAARVLKHYNASRVAVDVIKVKGLANTDAAHFDAILMLHSWEAGAPTEIVQAFMDKSPESEKKIVMLTTSWNGLEQMENIDAITGASIMVDVSVFTDQIIKRLDRLLKNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK47</accession>
    <name>A0A5C6ZK47_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF3127 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08585</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021474">
        <property type="entry name" value="DUF3127"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11325">
        <property type="entry name" value="DUF3127"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="123" mass="13997" checksum="F4D16BB0284B496A" modified="2019-11-13" version="1">MEVQGKIKMIGETQTFGSNGFRKRELVVTTEEQYPQHIMVEFVQDKTDLLNNYQVGQEVKVNINLRGREWVNPQGETKYFNSIQGWRIEAGQAAGNNAAPKAPNEAFEPATNLNEEDHDDLPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK56</accession>
    <name>A0A5C6ZK56_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Gliding motility-associated protein GldE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">gldE</name>
        <name evidence="12" type="ORF">ESY86_08645</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04590">
        <property type="entry name" value="CBS_pair_CorC_HlyC_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002550">
        <property type="entry name" value="CNNM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044751">
        <property type="entry name" value="Ion_transp-like_CBS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019862">
        <property type="entry name" value="Motility-assoc_prot_GldE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005170">
        <property type="entry name" value="Transptr-assoc_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03471">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01595">
        <property type="entry name" value="DUF21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01091">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03520">
        <property type="entry name" value="GldE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51846">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0129">CBS domain</keyword>
    <keyword evidence="6 8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="20"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="76"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="143"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="CNNM transmembrane" evidence="11">
        <location>
            <begin position="16"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="10">
        <location>
            <begin position="223"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="10">
        <location>
            <begin position="286"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TXD89440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="436" mass="49365" checksum="62E6016A894746E8" modified="2019-11-13" version="1">MDPEPISSFLLPLLNIDLALIFGLVLLVVLLLCSALISGAEVALFSLTKSDLDTGLSEQSKAFDIIVRLLERPKKLLATILVANNFINIGIVILFAYLSETIFQSVTIGWVRFLLEVVVITFLILLIGEIVPKIYASRNRNKFSMFMAIPLRVLDVVFSPVSLPMRQITIAIHNKLGKQKSNLSIDQLSQALELTNNSDTSVEEHKILQGIVSFGNTDTKQVMRPRVDIFAINEDQKYADILPEIVKNGYSRIPAYKDNIDNVTGILYVKDLLPYVDRKQFDWTTLLREPFFVPENKKLDDLMAEFQDKKVHLAVVVDEYGGTSGLISLEDVIEEIVGDISDEFDDEDINFVKIDAKNYSFDGKTTLKQFYKIIDQNVEEVFENHKGEAETIAGFILEISGIFPKRLSKINFKNFVFTIEALDKKRIKQVKFTILD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKC3</accession>
    <name>A0A5C6ZKC3_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">2,3-bisphosphoglycerate-independent phosphoglycerate mutase</fullName>
            <shortName evidence="8">BPG-independent PGAM</shortName>
            <shortName evidence="8">Phosphoglyceromutase</shortName>
            <shortName evidence="8">iPGM</shortName>
            <ecNumber evidence="8">5.4.2.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">gpmI</name>
        <name evidence="14" type="ORF">ESY86_06015</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>(2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate</text>
            <dbReference type="Rhea" id="RHEA:15901"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="EC" id="5.4.2.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="8">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the BPG-independent phosphoglycerate mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.12" evidence="8"/>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00186"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046537">
        <property type="term" value="F:2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006007">
        <property type="term" value="P:glucose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16010">
        <property type="entry name" value="iPGM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1450.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01038">
        <property type="entry name" value="GpmI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011258">
        <property type="entry name" value="BPG-indep_PGM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006124">
        <property type="entry name" value="Metalloenzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036646">
        <property type="entry name" value="PGAM_B_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005995">
        <property type="entry name" value="Pgm_bpd_ind"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31637">
        <property type="entry name" value="PTHR31637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06415">
        <property type="entry name" value="iPGM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01676">
        <property type="entry name" value="Metalloenzyme"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001492">
        <property type="entry name" value="IPGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64158">
        <property type="entry name" value="SSF64158"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01307">
        <property type="entry name" value="pgm_bpd_ind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="7 8 14" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 8 11" id="KW-0464">Manganese</keyword>
    <keyword evidence="4 8 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metalloenzyme" evidence="12">
        <location>
            <begin position="3"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="domain" description="iPGM_N" evidence="13">
        <location>
            <begin position="81"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8 10">
        <location>
            <begin position="152"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8 10">
        <location>
            <begin position="259"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphoserine intermediate" evidence="8 9">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8 11">
        <location>
            <position position="11"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 11">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="332"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 11">
        <location>
            <position position="399"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 11">
        <location>
            <position position="403"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 11">
        <location>
            <position position="440"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 11">
        <location>
            <position position="441"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 11">
        <location>
            <position position="458"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001492-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001492-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR001492-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF06415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TXD90289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="505" mass="55772" checksum="7C8F91CEBD08AC67" modified="2019-11-13" version="1">MNKKVILMILDGWGLSPDPKVSAIDNANTPFIDSLYTKYSHATLRTDGLNVGLPEGQMGNSEVGHMNLGAGRIVYQDLVKINLAVKNNTLKDEQILVDAFTYAKNNSKDVHFLGLLSDGGVHSHIEHLFGLIDAANDFGIDHSYVHAFTDGRDVDPKSGFGFVTSLQEHIKNTNTQLATVTGRYYAMDRDNRWERIKVAYDALVNGVGKHSGNATQSLENSYDHDITDEFIEPIIMTNADDDPVTSIKNGDVVIFFNFRTDRGRELTSALSQMDFREQNMHKLDLYYVTMTNYDASFTGTKVVYTKDNLSETLGAVLEKNEKKQIRIAETEKYPHVTFFFSGGQETPFKGETRILRDSPKVATYDLKPEMSAFELTDALVPELEKGEVDFVCLNFANGDMVGHTGVMEAAIKACEAVDTCVKRVIETALQNDYATILIADHGNCETMINPDGSPNTAHTTNPVPVILIDNDKTAIKDGVLGDIAPTILKLMGVEQPKVMTQAALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKE0</accession>
    <name>A0A5C6ZKE0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">YitT family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_04685</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019264">
        <property type="entry name" value="DUF2179"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003740">
        <property type="entry name" value="YitT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10035">
        <property type="entry name" value="DUF2179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02588">
        <property type="entry name" value="YitT_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006483">
        <property type="entry name" value="Membrane_protein_YitT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="117"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="190"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2179" evidence="8">
        <location>
            <begin position="258"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF10035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD90055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="325" mass="35730" checksum="AA37B98B450F70AD" modified="2019-11-13" version="1">MNPFITKILLKIAQKRVDEKLAPGKAPNSQNQVALIANNLYVELMHAIKEYAFIIIGVFSAGFGLKGFLLPNKFIDGGATGISLLIQNLSGMSLGILLLLVNLPFILLATKTIGKKFAIKSIISIMFLALVVHFVEYPVITEDKLLIAIFGGFFLGLGIGLAMRGGSVIDGTEVLAIFLSRKLSITIGDVLLLINIIIFSFGAYVLSIEIALYAILTYLAAAKTVDFVVDGVEEYIGVTIISEFHEDIRKVLTEKLERACTIYPAKGGYKNETAHYDKSVIFIIITRLELPRLHTEIEKIDKNAFTIMTVVKDLKGGMIKKKSFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKH1</accession>
    <name>A0A5C6ZKH1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">YncE family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03105</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011048">
        <property type="entry name" value="Haem_d1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011964">
        <property type="entry name" value="YVTN_b-propeller_repeat"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51004">
        <property type="entry name" value="SSF51004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02276">
        <property type="entry name" value="beta_rpt_yvtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023057290" evidence="1">
        <location>
            <begin position="24"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="353" mass="37697" checksum="F97CB7715FDD61C5" modified="2019-11-13" version="1">MNTKTLVFLLLCLSLFFASCTNDDDGIIAQPSGDYANGLLISHEGNFGQGNASVSYVSYDFQTVENNVFSNVNGTPLGDSAQSIAFDGDLAYIVLNVSNKIEVVNRYSFESVATITSGLNNPRYMAIANGKGYVTNWGDGGDATDDYLAVIDLSNNAITSQVISVEEGPEKIVGDGNRLYVAHQGGFSQNNIVSVIDAMSNSVSATIEVGDVPNSMQLDAAGNLWVLSGGKPAYTNDETAGKISKINTNTNTVTSLDFAMTEHPNLLNIDNGQVYYYLAGSVYKMDATAIALPTSAQLTGLNFYGMLVENEIVYGLDAVDFSSNGSLNVYDLNTNTEVESIELNIIPGEVYLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKJ4</accession>
    <name>A0A5C6ZKJ4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Putative glutamate--cysteine ligase 2</fullName>
            <ecNumber evidence="2">6.3.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Gamma-glutamylcysteine synthetase 2</fullName>
            <shortName evidence="2">GCS 2</shortName>
            <shortName evidence="2">Gamma-GCS 2</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_10280</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 2">
            <text>ATP + L-cysteine + L-glutamate = ADP + gamma-L-glutamyl-L-cysteine + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13285"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58173"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.2" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004357">
        <property type="term" value="F:glutamate-cysteine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042398">
        <property type="term" value="P:cellular modified amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01609">
        <property type="entry name" value="Glu_cys_ligase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006336">
        <property type="entry name" value="GCS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011793">
        <property type="entry name" value="YbdK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04107">
        <property type="entry name" value="GCS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02050">
        <property type="entry name" value="gshA_cyan_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 3" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="365" mass="41925" checksum="D00F0C2EC831518F" modified="2019-11-13" version="1">MKFTLGIEEEYQVICPETRELISHDQQIVSNAARLLNEQVKAEMHQAVVEVGTNICLDINEARTEITHLRKSIAGIAKDLGFKIGAAGTHPFSKWETQLITPNPRYDEIVNELQDTARSNLIFGLHVHVGIEDKQLALHLVNAMRYFLPHLYALSTNSPFWEGRNTGFKSFRSKVFDKFPRTGIPGVFDTVAQYEHYIDILIKTKCIDNPKKIWWDIRIHPFFPTLEVRICDVPMTIDETLSIAALIQALVVKLYKLRTQNLNFMLYHRALINENKWRAGRYGLDGKMIDFGKECEVDTRDLMEELLEFVDDVVDELGSRKDIENIRNIMKNGTGADRQLAVFEKTNDLVKVVDYITEQTILGTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKP9</accession>
    <name>A0A5C6ZKP9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Multidrug efflux SMR transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_07360</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the drug/metabolite transporter (DMT) superfamily. Small multidrug resistance (SMR) (TC 2.A.7.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000390">
        <property type="entry name" value="Small_drug/metabolite_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045324">
        <property type="entry name" value="Small_multidrug_res"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30561">
        <property type="entry name" value="PTHR30561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00893">
        <property type="entry name" value="Multi_Drug_Res"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="33"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD89597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="108" mass="11775" checksum="B5EC9AD11DD8F9B7" modified="2019-11-13" version="1">MNWLLLIIAGLFEVAFAFCLGKAKHASGNETLYWYLGFLVCLIVSMSLLVRVTQELPIGTAYAVWTGIGAVGTVLIGIFIFKEPATFARVFFICTLIASIIGLKLVSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKT2</accession>
    <name>A0A5C6ZKT2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">OmpH family outer membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_09460</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Skp family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.910.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005632">
        <property type="entry name" value="Chaperone_Skp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024930">
        <property type="entry name" value="Skp_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35089">
        <property type="entry name" value="PTHR35089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03938">
        <property type="entry name" value="OmpH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00935">
        <property type="entry name" value="OmpH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111384">
        <property type="entry name" value="SSF111384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="66"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="177" mass="20219" checksum="BB91E0879CBBC387" modified="2019-11-13" version="1">MNKISLTLALLALITSISSFFYFNSHSNQVYVDVNKLLEGYKRTKVVRADFDATAKTLNANVDSLMTNWQTELKLYEKERSKMSDKELELKQELLGNKQQQINNYQQAIQKQIDESDKKSTQTVINDINDYVKEYGKRNDYDIIFGASGSGSIMYASEKADLTEKVLEGLNTEFDGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKT9</accession>
    <name>A0A5C6ZKT9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Outer membrane beta-barrel protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_03075</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027385">
        <property type="entry name" value="OMP_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13505">
        <property type="entry name" value="OMP_b-brl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022930964" evidence="3">
        <location>
            <begin position="20"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="domain" description="OMP_b-brl" evidence="4">
        <location>
            <begin position="7"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="468"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="557"/>
            <end position="584"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="763" mass="84553" checksum="A637127AD9C78149" modified="2019-11-13" version="1">MKKIITFCVLVSLGANVHAQMKDVTVTLQPTASYNWFDQNTAIEDGVMFGARVGFGFGEALELRGVYERSNDLKNTVNGFDVFSDNFVDNFNVRNVDVTRIGGEFKANIPTRGTFVPYFTLGAGVQTLEVNIAALNAPSNEQKSEQVYANIGLGTQIKLGNRLFLNLEAKNTIFNMNPASILYQEGQDQSDIEGWLNDNNNSRMYNWSVLAGLQVYLGGRSPEEFSALDRAYYNKFSGGLGGFKLILEPAGAYIDFDKDTNFRDSYFLGGKIGFDLNQYIGIRGYYYQSTRDEKISFDWDDMGIYGADFIAKLNVSRGLVPYVSLGGGYINVYNETYLGRDGLTGASSGYFAKGGVGLNVPVGRNLELFGDANLLFTSERDNNDLENTISPDELKQHTMFSVGLRFQLGKRADNTDEILRDEIDQRVEDRTQVYQDRIKELESELSDAYKNNDTKKAVAIIEEKKELERENGISQEAKGTSKKTEQESKVEMTPKELEELIEKVIQGVDEESSKPRTINDRMDRLERLLLEINTGNYRENLTPARQEDASQKILDRLNELDRNIEKNTDRIDNLNGNLRNQNQDQDKTVVISSGQQAPIAAPQMAQASETKVVTDADGNTVVETENATNGVATGVVINEGLSVFTGVAIADDVSMIIGIRGNYSFTNSPFKFMPDLYLAPGENTGFGINANVVIPFEVNAGVILNPYIGAGIGYNDAVGESTFSPNLIIGTSFNLLGGKLFADYTAHNFVDIHRISVGYKLNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKU4</accession>
    <name>A0A5C6ZKU4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptide methionine sulfoxide reductase MsrA</fullName>
            <shortName evidence="4">Protein-methionine-S-oxide reductase</shortName>
            <ecNumber evidence="4">1.8.4.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Peptide-methionine (S)-S-oxide reductase</fullName>
            <shortName evidence="4">Peptide Met(O) reductase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">msrA</name>
        <name evidence="6" type="ORF">ESY86_03600</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>[thioredoxin]-disulfide + H2O + L-methionine = [thioredoxin]-dithiol + L-methionine (S)-S-oxide</text>
            <dbReference type="Rhea" id="RHEA:19993"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58772"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 4">
            <text>[thioredoxin]-disulfide + H2O + L-methionyl-[protein] = [thioredoxin]-dithiol + L-methionyl-(S)-S-oxide-[protein]</text>
            <dbReference type="Rhea" id="RHEA:14217"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12315"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:44120"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the MsrA Met sulfoxide reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.11" evidence="4"/>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033744">
        <property type="term" value="F:L-methionine:thioredoxin-disulfide S-oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008113">
        <property type="term" value="F:peptide-methionine (S)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01401">
        <property type="entry name" value="MsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002569">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036509">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01625">
        <property type="entry name" value="PMSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55068">
        <property type="entry name" value="SSF55068"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00401">
        <property type="entry name" value="msrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PMSR" evidence="5">
        <location>
            <begin position="6"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD90462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="164" mass="19071" checksum="40D1A89980B6E3BB" modified="2019-11-13" version="1">MSDYKKAYIAGGCFWGMEDLFRTRPGIIDTEVGYIGGQNEHPTYRSHPGHAEGIEITYDPNETSFKRILDYFFRIHNPTTLDQQGNDMGSSYRSAIFFQNEEEKQEAQEVIKIVDDSNKWEGDAVTTLEPYSTFWAAEPEHQDYLQKKPNGYTCHFERFDKSFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKV8</accession>
    <name>A0A5C6ZKV8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PAS domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03095</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="1">
        <location>
            <begin position="83"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="181" mass="21135" checksum="B2C74B79A09CDB44" modified="2019-11-13" version="1">MMGLDVYLSTLNEDEYDHAETAITPQNLQTMPLLSWDIFSTGHFDKLKNLNRAEDIAKVMALGKKFKWTNDLNEIFHEEDFEALVLTDLHQKIVWVNNGFTEMTGFIKSEALKNTPRFLQGPKTNVQIKDRFRKKLLKDEPFAEVITNYKKNKTEYACEVKIFPLYNEKTIHYLALEKQVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL41</accession>
    <name>A0A5C6ZL41_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">2Fe-2S iron-sulfur cluster binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_01955</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="6">
        <location>
            <begin position="2"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="5">
        <location>
            <begin position="267"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD90749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="357" mass="40136" checksum="A843494889CD7A76" modified="2019-11-13" version="1">MAEFHNIKIGDIYKETDDTTVVTFDIPEELQDDFHFNQGQHLTLKTMIDGEDVRRSYSLCSSPLDKKWQVAVKLIPSGKFSTYINEQLKAGDTMEVMLPSGTFGVSVQPEAAKNYLFFAAGSGITPVLSMVKTHLLAEPKATCKLFYVNKTAKSIIFKEELEQLRNRFFGRLEIYYFLTREKRDIYLFNGRFDDEKMDVLTKTFIDIPDTSEVFLCGPEQMVNYVSNYLIAAGLPKDLVHFELFVSGLSEEDIERTARLSKQKVEGVKVTILDGGKEFTFTMTKDFDNILDAALGAGADLPFACKGGVCSTCKCQVKEGSVEMKVNYALEDKEVAQNYVLSCQSVPTSEKVVVDFDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL73</accession>
    <name>A0A5C6ZL73_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Class I SAM-dependent RNA methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_03290</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000241">
        <property type="entry name" value="RNA_methylase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004114">
        <property type="entry name" value="THUMP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02926">
        <property type="entry name" value="THUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01170">
        <property type="entry name" value="UPF0020"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00981">
        <property type="entry name" value="THUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51165">
        <property type="entry name" value="THUMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="THUMP" evidence="3">
        <location>
            <begin position="46"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD90405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="386" mass="44209" checksum="CABD3A25FE70A1FF" modified="2019-11-13" version="1">MENNYTMVAKTLFGFEDLLERELLQLGAMHIKKGVRNVSFEGDKGFMYKANLALRTAIKILKPIKSFKVRNEQDLYDQVYKMPWHDYLKSNGTLAVDATVHSEVFTHSKYIALKTKDAIVDKFRDLDGERPNVDLRFPDLKINVHIDRNMCTISLDSSGESLHRRGYKTATNIAPINEVLAAGLVMLSGWDGQSDFMDPMCGSGTILAEAAMIACNIPPNLMRKEFAFERWQDWDVDLFEKIEASLLSKTREFYHKIIGYDKSPSAIAKATDNIKNAHLEEFITLQHHDFFKTEKEGDAKLHMLFNPPYGERLDIDMETFYKDIGDTLKQGYPGTDAWFITSNLEALKHVGLRPSRKIHLVNAKLEARLVKYVMYEGSKKAKHQED</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL90</accession>
    <name>A0A5C6ZL90_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Acetylglutamate kinase</fullName>
            <ecNumber evidence="7">2.7.2.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">N-acetyl-L-glutamate 5-phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">NAG kinase</fullName>
            <shortName evidence="7">NAGK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">argB</name>
        <name evidence="9" type="ORF">ESY86_02230</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the ATP-dependent phosphorylation of N-acetyl-L-glutamate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + N-acetyl-L-glutamate = ADP + N-acetyl-L-glutamyl 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:14629"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:44337"/>
            <dbReference type="ChEBI" id="CHEBI:57936"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Amino-acid biosynthesis; L-arginine biosynthesis; N(2)-acetyl-L-ornithine from L-glutamate: step 2/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the acetylglutamate kinase family. ArgB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.8" evidence="7"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00107"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003991">
        <property type="term" value="F:acetylglutamate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042450">
        <property type="term" value="P:arginine biosynthetic process via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00082">
        <property type="entry name" value="ArgB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004662">
        <property type="entry name" value="AcgluKinase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037528">
        <property type="entry name" value="ArgB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000728">
        <property type="entry name" value="NAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00761">
        <property type="entry name" value="argB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="1 7" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AA_kinase" evidence="8">
        <location>
            <begin position="5"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="40"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="8"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD90799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="258" mass="27980" checksum="3D7A2519069F32CD" modified="2019-11-13" version="1">MKTLKIIKIGGNIIDDASSLSAFIELFAKLEGPKILIHGGGKLATKLATDLGMEVNMIDGRRVTNAATLDIITMVYAGKINKNIVVQLQAKHCNAIGFSGADGNTIVSKKRPATPIDYGFAGDIAQVNTAVLEVLLTQGVAPVFCALTHDQNGQLLNTNADTIASELAIAFANTYETELYYCFEKNGVLRDVDDETSVIKHISTENYQDLMQQRIISEGMLPKLLNCIYAIQKNVNKVCIGKPEMLSNPNANFTTITK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLG5</accession>
    <name>A0A5C6ZLG5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phage tail protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_00525</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011747">
        <property type="entry name" value="CHP02241"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010667">
        <property type="entry name" value="Phage_T4_Gp19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38009">
        <property type="entry name" value="PTHR38009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06841">
        <property type="entry name" value="Phage_T4_gp19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02241">
        <property type="entry name" value="TIGR02241"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="150" mass="16836" checksum="CB44CC5C9E11A5B3" modified="2019-11-13" version="1">MASAMPFSGFHFSVVFELLPQFSIDTKFQSVSGLTSTMEMESISEGGQNRFKIALPKGNDFDDLVLKRGVTNDFSGLRLWVNNALQSFVFVPANLLVMLLNEEHNPVKAWYVIKAIPKAFSISDFNAEASTIVFETLTLDYQFFNEIPIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLI8</accession>
    <name>A0A5C6ZLI8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Rhomboid family intramembrane serine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_00655</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="SSF144091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="102"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="130"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="165"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="Rhomboid" evidence="6">
        <location>
            <begin position="63"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD91134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="290" mass="32953" checksum="02DAC54818641BEF" modified="2019-11-13" version="1">MTSLNYDFKEKLKNLNVFEKIMIANVLLYLLGWLIQLILKLPRGYGLSWLELPRDFTDFIVKPWSLLTYGFTHYDFLHLLFNMLVLYFVSRSMVNMFPSKQSLNIYFMGILAGGFSYLLIYNVLPESMMATVGALVGASAGVNALLIFLCTYMPNQEARFFTIRIKLWHIGVAIVVFDIIGLFGVNQGGKVAHLGGSLLGYLYASNLLKGSDIGIGFGKLVDQVSNWFKPKSNLKTVHRTKKKPFAGHNKNEFNEFSHQKKIDIILDKISKSGYESLTKEEKEFLFKAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLU5</accession>
    <name>A0A5C6ZLU5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Electron transfer flavoprotein subunit alpha/FixB family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_02530</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ETF alpha-subunit/FixB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014730">
        <property type="entry name" value="ETF_a/b_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001308">
        <property type="entry name" value="ETF_a/FixB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014731">
        <property type="entry name" value="ETF_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43153">
        <property type="entry name" value="PTHR43153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01012">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00766">
        <property type="entry name" value="ETF_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000089">
        <property type="entry name" value="Electra_flavoP_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00893">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ETF" evidence="2">
        <location>
            <begin position="3"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="320" mass="33564" checksum="A2DCEAA6BD17EEFE" modified="2019-11-13" version="1">MSVLVYTESEQGKFKKVALEVASYAKAVADQMGTSVTAITINADDISELGNYGVDKVLKVNSSDLEKFNANSYANVIKQAAEKEDTKVVIVSSSADSKYLAPLLAVGLEAGYASNVVEAPSSASPFTVKRTAFTNKAFNMTTIDTDVKIVGVSKNAFGLKEHKADAAAEDFSPSVPESGVHVESIDVATDKVTIADAEIVVSAGRGLKGPENWGMIEELADVLGAATACSKPVSDLGWRPHGEHVGQTGKPVASNLYIAIGISGAIQHLAGINASKVKVVINNDPEAPFFKAADYGVIGDAFEIVPALIEKLKTFKAQNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZML6</accession>
    <name>A0A5C6ZML6_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Na(+)/H(+) antiporter NhaA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Sodium/proton antiporter NhaA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 8" type="primary">nhaA</name>
        <name evidence="8" type="ORF">ESY86_04065</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>2 H(+)(out) + Na(+)(in) = 2 H(+)(in) + Na(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:29251"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015081">
        <property type="term" value="F:sodium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006885">
        <property type="term" value="P:regulation of pH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01844">
        <property type="entry name" value="NhaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023171">
        <property type="entry name" value="Na/H_antiporter_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004670">
        <property type="entry name" value="NhaA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30341">
        <property type="entry name" value="PTHR30341"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06965">
        <property type="entry name" value="Na_H_antiport_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00773">
        <property type="entry name" value="NhaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0050">Antiport</keyword>
    <keyword evidence="3 7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0915">Sodium</keyword>
    <keyword evidence="7" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="64"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="103"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="185"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="210"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="306"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="332"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="374"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="408"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD90551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="438" mass="48017" checksum="C13B6C6693223480" modified="2019-11-13" version="1">MIKEVFLSPFQKFVKIESFSGILLLLATIIALVWANSPFGDTYRELWQYDVGIVTKTFEFKKPLILWINDGLMAIFFFLIGLEIKRELMIGELNSAKKIAFPLVGALGGMLVPVVFFLVLNQNPETAKGWGVPMATDIAFSLAILNTLGNRVPLSLKVFLTAFAIVDDIGAVLVIAIFYSGSINLTLLSIALVMLAVLYLLSYKGYYSRFLVFFLGLSVWFLFLKAGIHPTVAGILLAFAIPIRQKINTSAFLVQLEKVYNDIKNASILQKPLLSNEQISSIDDLDDWARKFQSPLQHLEHNLHGWVAYFVIPIFALANAGVLIGNTDDLDTALITNIVICLILGKGIGITSLVLLAQKMRLIEVPSEISFKQIVGVAFLAGIGFTMAIFIASLAFASSPEFIDSAKIGILIGSFISAIIGYGILRAGSNKEPNVKIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMQ3</accession>
    <name>A0A5C6ZMQ3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_01145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023059483" evidence="1">
        <location>
            <begin position="22"/>
            <end position="731"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="731" mass="84511" checksum="B58DCA33D5A198AC" modified="2019-11-13" version="1">MKLRTYVLVVYALFSASFISSQTTDSVANKIADAFNELSNFRTFDNIYLQTNKDIYETEEDLWFKAYILDAHYFTPSVRDHVLVVQLINEDTQRTIWKEKYEILDGFVNGHVYIPSTIEFGNYTLMAFTSHSFYKDSNSFFSFRTISIVDKIDKSVKSGTDDPEKSVLHEFTLFPEGGDLISGIEHNLAFKATDKAGIPLEVSGKLFENNQAILDFETKHAGMGSFSFRFNKSNVYKIKLDQDSTESYDIPKIKLKGKSLQLVSQDEHEAIFKIAKNNYSEVDTVYLRLQSRGTVYSVAAMALKNQGFVKIPLKDIPQGIAEVTLLNQNFQPIAERLIYVKPNQKLYIETTLDASEYKTREKIKLSIKVHDQYNAPVIATLGLSVVDQLYKNKHDPKTIMSHYYLSSQLKGAIYDPNYYFNPENEDRQHALNLLLLTQGWRRYVWSENELHSLSKSDYKIIPDPLEGIVYAKQKSRNKTPTHPFVIVYSGVEQSDTYFLETNFANRFELNHEQLKLGKRGFIFLKPVGDSESEYRINIHDISFDSINHYRKSQAAYYPIIKETKTNNDANTAFFEYDSTQKLDEVILRKRKERAYRDKYLGRLDSLATVVIPDCVCEYNIVNCINHCPQKQETYSEEELLKMFNLTMIKGFYGKREFYSPTYEAQTPEDDFPDYRNTLIWKPDIITDTLGEAEIEFFCSDIFGNFNVTIEGVGQNGLLGSETLDFIVRKKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMQ6</accession>
    <name>A0A5C6ZMQ6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Gliding motility protein GldN</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">gldN</name>
        <name evidence="2" type="ORF">ESY86_05660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019847">
        <property type="entry name" value="Gliding_motility_assoc_GldN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19841">
        <property type="entry name" value="GldN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03523">
        <property type="entry name" value="GldN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023127093" evidence="1">
        <location>
            <begin position="24"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="299" mass="34455" checksum="08F82CF89054AB36" modified="2019-11-13" version="1">MTYKFLLSIVASVGLTSGMFAQANILNAKTPKEVGVKTEAQLALDHDKPLEYGYVDDRDILFSKMTWEKVVLDERVNFPLYFPVDTNNIGKNRRSLYHTLISAVKSGKIKNIYNDSYFSSKRTEKELQDITTKVDTLDIGYDQLNADGFVSPEYITTTNIEAFHISAYLIKGLWYFDKRLGELKYRILGIAPAAPDVNFLESENEAQKVPNALFWVFYPEARQALNDADAFNNQNSSAPITFDHLLNSRRFSGFMYKEENVYGDREVKDYVADNALMQLLESDRIKDKIRDFEQDMWNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMZ0</accession>
    <name>A0A5C6ZMZ0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_01695</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025631">
        <property type="entry name" value="Porin_10"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14121">
        <property type="entry name" value="Porin_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="650" mass="75064" checksum="F71D0E8E143510EA" modified="2019-11-13" version="1">MRNPIFITFFILSCFGTLNCQTLKKNNNQSFPSGISKDSSKVKRQKNFGLKDSISIFYYKIISIENDTTIVDTSLTIKKDYKFNYLRRDEFGLIPFANAGQTYNALKLDRNSKLLPVFGARARHYNYMEVEDIDYYEVPTPFSELFFKTVFEQGQILDAFFTINTSRQFNMSVAYKGMRSLGNYQNSLTSTGNLRLTSNYHTKDERYHLKGHITFQDLLNNESGGLTDFDVEQFTSGSDEFLDRSVFDPAIQNADNILEGKRFYLNHSYALIREADSTSGTLILKNRVSFEDKYYQFNQSLRDDYFGPAFSRRIKDRVTLENFEANLAALWKSVIGEVSFGVTYNKLNYGYDFSTIIDNEYIINRIVTNTIALEGSYKKQFGDVNLWTKASTIVSGEFSGYQFEAEASYQFDEDNEIIANFSSASAASNFNTLLYQSNYINYNWYNKDRFSNEKTSQIGLDLNLNKIADFSLDYTVYNDYTYFAFSEENAGVKPFQEAQAISYLKFSAGRQFEIGKFSLDNKVMYQQVGGVEGVINVPDLILRNSLYYSDGLFKNDALFLQTGITFNYFTEFNANAYDPLLAEFYVQNNTKLGNFPRLDVFVNAKVRQTRIFLKAEHVNAAFTGYDYFAAPNYPYRDFNIRFGIVWNFFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN97</accession>
    <name>A0A5C6ZN97_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_05300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018534">
        <property type="entry name" value="Tet_reg_excision_RteC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09357">
        <property type="entry name" value="RteC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="278" mass="33371" checksum="65D11B9C58A612A7" modified="2019-11-13" version="1">MKLHLLAQNLEKQLLEIEENSETIMQRSKHSIIVCTKLLGQFKKEIINKGFASISDEIYFFKHTKQIPLRHLIYFSEIRSFEIQFPKTDKESQRKFIRRKMQKVNRFFSYNLDFTQYADSKHTHFDKEYYTREYLGSYIIATSKFYFQDPEFCTPRDMLLGKYKAYDFLVTYLDEKKNKIRNGLNGKLRTIKPIEKIHWPFSNTDYVELLYSLCSKGLGKQDNQGIMQVSKKLQQIFDFKPKDIYKTYHDIKNRKNSRTLFLDELSTSLLIEMDKSEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNP4</accession>
    <name>A0A5C6ZNP4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Serine O-acetyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.30</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_05085</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetyl-CoA + L-serine = CoA + O-acetyl-L-serine</text>
            <dbReference type="Rhea" id="RHEA:24560"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:58340"/>
            <dbReference type="EC" id="2.3.1.30"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.30" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009001">
        <property type="term" value="F:serine O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd03354">
        <property type="entry name" value="LbH_SAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045304">
        <property type="entry name" value="LbH_SAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042122">
        <property type="entry name" value="Ser_AcTrfase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD90310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="270" mass="30049" checksum="68B8B1424A4416F9" modified="2019-11-13" version="1">MDQSTLIQAITQQKQEINVSVTLKQESQRFTTLLFNVLFDRGTDAEKALVELEALFLKIRDLACPEIKGAPCKRWEDFTQIIPDLFGSLKKDAMAIYNNDPAARSIEEVYLAYPGFFAIAIYRMAREFFVLGLPLIPRLMTEYAHQLTGIDIHPGAQIGSSFFIDHGTGVVIGETAEIHDNVKIYQGVTLGALKVKKQLQNIKRHPTIQKNVVIYANASILGGDTIIGAYSVIGGNTWLTESVAKNSIVLHTQDTQIITKSHKSDEQNDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNS7</accession>
    <name>A0A5C6ZNS7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Heme A synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_04480</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016653">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006784">
        <property type="term" value="P:heme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003780">
        <property type="entry name" value="COX15/CtaA_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02628">
        <property type="entry name" value="COX15-CtaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="141"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="171"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="211"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="252"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="285"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="311"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD90653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="347" mass="40301" checksum="AF33D898261E1F37" modified="2019-11-13" version="1">MQNTFRKTAKIAVVLIYIVIIAGAVVRMTGSGMGCPDWPKCFGYYIPPTDISQLQFHPDHEYKKGVIIMQNEQLWVAIEDFKSTEAINPIHWEVYTKHDYAQFNPTHTWVEYINRLSGVVAGIPILIFTIVSFWLWRKNKWLTILSIATVLGMGFQAWLGKTVVDSNLAPYKISIHMLMALVIVAFILYLIYASKSSFKDQVYDVRFKNLLIFAIILSLMQIILGIQVRQYIDEQVKAIGYVKSEWLDNPTLKFYVHRSFSIAVFLLNGWLWYRNRTLKLNYKKTNVLMLCILAEILTGILMYYFDFPFLTQPLHLVIATIMIGVQFYILLESRAKNRVEENRAINT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZP95</accession>
    <name>A0A5C6ZP95_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2183 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_02435</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008195">
        <property type="term" value="F:phosphatidate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019236">
        <property type="entry name" value="APP1_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09949">
        <property type="entry name" value="DUF2183"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2183" evidence="1">
        <location>
            <begin position="196"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="334" mass="38532" checksum="0B1F43D672304FBF" modified="2019-11-13" version="1">MGWFKKDPLQIISFQSYGTDSHFFARGRTLEDESIDLESQKIWHLAVNTWKRFKTDEIRNVGVNIKLPNGKILKTTTDADGYFRVEANLKALEALTNEQGWLAYELSYDDVNIKRSIQNENRFPGELLIPADTAQFGVASDIDDTILQTGIVSLLKWRVIYNSIFKNAKNRTPLEGAADFYQQLHQGVSGENANPIFYVSHSPWNLYRYLEVFLKQNNFPKGPILLRSLSNFLRKKPEGEKPQKQKEILDLLKTYPKLPFILIGDSGEHDPDIYMEIAEEFPDRILAIYLRSVKHKKRMLRVKGLVENYKTTAFLMVESSKQAIAHAREQGFIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPB5</accession>
    <name>A0A5C6ZPB5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_03805</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="252" mass="29855" checksum="423DC53B2D3686ED" modified="2019-11-13" version="1">MRLIFLLIILFFSKQIVFAQVEEHQVSYTTASKDTLRVDRSNQPIAKKAYDYKLDSSLFSVLRFENDSLVLYKLRLSYMFGNLVPETKTQLYQLLHSKNQVDTSRVMVIHYQDTLRAISYFPEKSKTVYAKDSMSHRHIANHQAFINQHKNCLKKNKRGRRNNVYHFFGYNEGHPAAFDKILWKKDHLGLVDQIYRDSYDRFNTIILHPDGTFVGYNYNDDTGKIYQDLIKGKRWELYKADFEKRVKALDAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZQ63</accession>
    <name>A0A5C6ZQ63_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BatA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_00235</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024163">
        <property type="entry name" value="Aerotolerance_reg_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011933">
        <property type="entry name" value="Double_TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07584">
        <property type="entry name" value="BatA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02226">
        <property type="entry name" value="two_anch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="618"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="domain" description="BatA" evidence="2">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD91063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="641" mass="72121" checksum="07640A0A440B2A16" modified="2019-11-13" version="1">MQFKYPELLYALLLLVIPIIIHLFQLRKFQKVGFTNVQFLKQLTIQTRKSSQLKKWLILLMRLLLLACIIIAFAQPYSAKTNDYKTKSETVIYLDNSFSMQAKGANGSLLNSAIQDLLERLDAEEPISIFTNNANFSNTTIKAIKNELINLGYAPKQLSYEATVLKGKQLFTDDASAIKNLLLISDFQQQQEGFSTAIDSSVQVKMVQLQPENINNISVDSVFISEAKVENIELSVTLKNYGAATENVSVSLFNQDKLVAKNAVDIEDQANVTFTIAQNKRFDGSISIEDPNLQYDNTLYFNLDETEKIKVLSINSAEDVFLRKIYTTDEFEYSSSAFGSLDYNAISNQNLVVLNELDEIPVSLATALKVFSDDGGSILIIPSSDIVLNTYNQLFTNFNLAAFSSKSSQEKRVTAINFSHPLFENVFEKRISNFQYPKVQDHYGTASSSSQNILSFEDGQAFLSAAQKVYRFSASLSESNSNFKNSPLIVPILYNIGKQSLNTGRLYANISEENKIDINASLQPDAILTLAKGEETVIPLQRRFSNKVEITASNYPEQAGIVAVMHKEKFLKNLSFNYDRAESVLRYMDLTSLKNANVQDSVASAIDEIKSATNVNELWKWFVIFALFFLIIELLILKFFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZRM2</accession>
    <name>A0A5C6ZRM2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF2807 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_01235</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021255">
        <property type="entry name" value="DUF2807"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10988">
        <property type="entry name" value="DUF2807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022987718" evidence="1">
        <location>
            <begin position="21"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2807" evidence="2">
        <location>
            <begin position="41"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD91240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="277" mass="31066" checksum="EFEDBEF8B9D605A3" modified="2019-11-13" version="1">MRRFIFILATILSCPGLVSAQELEKVKGNRELTIKQTYVDEFEKIVVGQDFEVELFYNKKPSVEIETDDNLHEYIEIQVVAGVLSLKSVGDIRPKQLNIKINYGETFKDIEVNDDAEIRSLTSLELTNANLKTTGSSRAYLNIKADQFNFTALDKAKVKLNITANNASIIMSDNARMDALINAPETKIDLYQRVNANVEGTATNLTIRTDNDSQFDGKNFSVKNCTVNAEVSSEVTTEVMEQINIEASGSSEIYLYGNPKITINRFTESAKLQKKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZRP5</accession>
    <name>A0A5C6ZRP5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_01345</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="288" mass="30655" checksum="3B4F13D1115D75DB" modified="2019-11-13" version="1">MKSLLSLIGIFLIFITTSSAQIGIGIPTPDASSILHLESTNSGLLLPRLTTAQRGTIASPATGLVIYNTNTSAVEMNTGTPASPIWSRAASTTAPVIPPSVITAQMDMLPQTVGSLVYNTTESCLFQYKGAPFNKWQSLCEKESSKILTLYKSGGPNLIGNGTFVNVPLGGTASQVQERDSDYFTVVSDGKIRVLQSGSYLINVSWSVQNLRGGTRKYKLAVFNNSVEIGTLASGFSSTPGSGNEYFGKAGVFQYQFAANDEIEIRYSVDNGGTTLTADLFHIGIVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6Z9K8</accession>
    <name>A0A5C6Z9K8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_20200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000060">
        <property type="protein sequence ID" value="TXD86439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="61" mass="7105" checksum="4D4BEA209274998D" modified="2019-11-13" version="1">MNSYHLKAILKRQVQIVELQKGKTGQELDESVQIEIDILNEKFSGWLKEDIISNVDNFSRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAL3</accession>
    <name>A0A5C6ZAL3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18565</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000032">
        <property type="protein sequence ID" value="TXD86995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="17"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="79" mass="9149" checksum="FDE8E9CB1338F259" modified="2019-11-13" version="1">MNINDKTEFLISFGKLLADHRQKRKLSYRELAQLCDVDHSQISRIEKGQVSIQLTTLFELARGLDVHPKELLDFKFTCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAN7</accession>
    <name>A0A5C6ZAN7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Outer membrane beta-barrel protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_18370</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000031">
        <property type="protein sequence ID" value="TXD87025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022732200" evidence="5">
        <location>
            <begin position="19"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="7">
        <location>
            <begin position="133"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="6">
        <location>
            <begin position="441"/>
            <end position="937"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD87025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="939" mass="104031" checksum="30F779038282C030" modified="2019-11-13" version="1">MKKLIILFTLFTTSFIMAQNTGSIVGMLTDKEYNNEPLAFANVLIKGTTTGTTSDFDGIYSLENLDPGPYTLVFSFVGYETQELVVEVVAGKVTTINVPMGANPGALDEIVITTTARKDSEVALLLDQKKAVEIKESIGAEQLTQLGVSDASGATAKISGVSKSEGTGQVYVRGLGDRYLTTTLNGLPVPSDNIDKKNIDLGLFPARFIQNVAVSKTFSPKNSSDQASGNIDIVSKEVTKRRTFGLSANGGVNSNIANVFDNFKVTANNSDVNFGLYSRAYEFDELSNAITGQSWTPQQISAPVNYSYGFNAGGIIGEARKLRLFISAGQSIENEYREGIFREYDQGNLRDSVPDGDNIRWRREVNTTGMFHGQFKFNDNNKVSLNSFIINKVFEETYEAGRSGGAVIFEELDGPQEGFQFVRDQNLKNTIISITQLIGEHNFSDDNKLEWAAGYNYVIANEPNRIRNEVNILNEDDRIQLGFTGGFQQRKSAQDITDKEYNARLQDEIILKKNENDDAIYKVSFGGNYRNKKRDFQSQFIGAEEAFTDAANPSSIDAISEIFTQSNFDNGILQLNTLQPDTYEGELVSYAGYADFIGVFNKFTAEVGLRYQSDAIDVGFDVGNYVDPATGISRIGTSNQSYERFYPAVNLKYNFTDKFAVRLAGSLSQTLPEFKEIAPFQYVSPENQVTQGNPDVEASRDLNVDLKFELFPTNEELLSLTAFYKQIKDPINRTLQRGGENIFSYFNSGNKATVIGVELEGRIYVVKKQDSLPNLKLSGNISYIDHKQDLKEIRDGDGNLLRTFKYGGKDEIGLEGASDWITNLALTLNTGSKYPYEFTLAGNYASDRIFSLGAPRNQNQPEVFYNGEITEQGVVVLDFIFSKDIDERWTIGATAKNLLNPTIKRVQLIESAVDGIRSEETVLSYSTGVNAAVSISYKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBG4</accession>
    <name>A0A5C6ZBG4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">IS30 family transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000046">
        <property type="protein sequence ID" value="TXD86627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025246">
        <property type="entry name" value="IS30-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13936">
        <property type="entry name" value="HTH_38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="164"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="334" mass="39252" checksum="CA2A5F0B2C757C9A" modified="2019-11-13" version="1">MKPKKYHRLSLQERVVIETLLAESRSKSYIALKLHRSRSTITREINKWGENYDARLADWCAKDDYLNKRNLDKINTYNKLKIYVYRGLLNAWSPEQISGKIKLDYPRDPIMAISYEAIYTHIYTHRQARLNRKLIALLPYQKSQRRRANAKSKRGVKIKDQTSIDDRPEHIEKREEIGHWEGDLVIVTGQKSAIGTLVERKARFTFIVKLGIRKSATVRKGFFREFRQADTIFKKTLTYDNGNEMAQHNQFTKQTGMPVYFAHPYSSWERGTNENTNGLIRRFFPKGTDFSKVSEKELKMVQEKLNNSPRKILGYRTPNEVFTLELLKGNLKKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBK7</accession>
    <name>A0A5C6ZBK7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_18550</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000032">
        <property type="protein sequence ID" value="TXD86993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="246" mass="28533" checksum="D0D36E02B857D7A5" modified="2019-11-13" version="1">MLIINNAQKKNKSEVINLIDIHKKPVLFWDTCSLLDIVRLPLPDRNNKVDTLSKVIEIKDKIVSNDIISLSSELCITEFNNHIENWSKRLESESKKLSKSHNKFIGFINKVNLTSQTISDIDLSIYKIEELLCQITHAIISNTIFVEEDDTFKEFAHFRTMNKIPPAQKKGEYKDCYIWATCLEIRNTNTDKSYPYYFISSNVSDYANENKKEFVTEISNEATINNIEYFSNFKIAFGILKSKNIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC06</accession>
    <name>A0A5C6ZC06_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA-specific adenosine deaminase</fullName>
            <ecNumber evidence="3">3.5.4.33</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">tadA</name>
        <name evidence="5" type="ORF">ESY86_18340</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>adenosine(34) in tRNA + H(+) + H2O = inosine(34) in tRNA + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:43168"/>
            <dbReference type="Rhea" id="RHEA-COMP:10373"/>
            <dbReference type="Rhea" id="RHEA-COMP:10374"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:82852"/>
            <dbReference type="EC" id="3.5.4.33"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the cytidine and deoxycytidylate deaminase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.33" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000031">
        <property type="protein sequence ID" value="TXD87019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052717">
        <property type="term" value="F:tRNA-specific adenosine-34 deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002100">
        <property type="term" value="P:tRNA wobble adenosine to inosine editing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00972">
        <property type="entry name" value="tRNA_aden_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016192">
        <property type="entry name" value="APOBEC/CMP_deaminase_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028883">
        <property type="entry name" value="tRNA_aden_deaminase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14437">
        <property type="entry name" value="MafB19-deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00903">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="2 3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="4">
        <location>
            <begin position="5"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD87019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="149" mass="16652" checksum="2581A549EA08A8CD" modified="2019-11-13" version="1">MENPFDDTYFMKKALQEAELAYEKGEIPVGAVIVIQDRIIARGHNLTELLNDVTAHAEMQAITAASNFLGGKFLHNCTLYVTLEPCQMCAGALYWSQIPKIIYAARDEQRGCIVMDTTLHPKTTMTGGLLAEEASALLKRFFIEKRNLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCQ7</accession>
    <name>A0A5C6ZCQ7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-hairpin-helix domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_16215</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003583">
        <property type="entry name" value="Hlx-hairpin-Hlx_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="SMART" id="SM00278">
        <property type="entry name" value="HhH1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HhH1" evidence="1">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="HhH1" evidence="1">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="HhH1" evidence="1">
        <location>
            <begin position="236"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="289" mass="33051" checksum="6D67F8D1AE49D8BF" modified="2019-11-13" version="1">MKSHFQFTRKQRSGIFLLLLLILIAQCAYFFIDFSSEEIQPNPTDLELFQAEVDSLKLVKQEAAKPKIYPFNPNYITDFKGYSLGMSNAEIDRLLNFRSTNQWINSAEDFQRVTQVSDSLLAVLSPNFKFPEWVTNPKPKPDYGYSSAVKPKSFQQKVDLNVATAAQLQKVNGIGEKLSVRIVEFRTRLGGKFIADVQLKEVYGLSPEVIERVLNEFTVKSAMPIKTVNLNTATLDQLVTIPHIDYEIAQQIIESRILREGFNSLEELTKVKEFPIGKFEIIRLYLTLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD11</accession>
    <name>A0A5C6ZD11_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GNAT family N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20115</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000057">
        <property type="protein sequence ID" value="TXD86484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="166" mass="19823" checksum="EBE6CEE21FF210F9" modified="2019-11-13" version="1">MIRKARAQDIDAIITITKACAKYMVSKEIFQWNEHYPNRAAFQKDFDRAELYVMELHENTIGCITLSTLMDAEYTPIHWQTKNSNNLYIHRLAVHPEFQGQGFAQKLMDFAEAFAKNHNFESIRLDTFSQNERNQNFYERRNYKQLGEIYFPKQSKKPFYCYELVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD97</accession>
    <name>A0A5C6ZD97_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000052">
        <property type="protein sequence ID" value="TXD86552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13443">
        <property type="entry name" value="HTH_26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="7"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="71" mass="7894" checksum="470FC80A6B594D6A" modified="2019-11-13" version="1">MPIIVNLDVMMAKRKMSLNELSDKVGLTLSNLSILKTGKAKAIRFSTLEAICKVLDCQPADILEYVEEPEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDA3</accession>
    <name>A0A5C6ZDA3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19860</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000051">
        <property type="protein sequence ID" value="TXD86565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018534">
        <property type="entry name" value="Tet_reg_excision_RteC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09357">
        <property type="entry name" value="RteC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="161" mass="19070" checksum="573E31B8163B4536" modified="2019-11-13" version="1" fragment="single">ADSKHTHFDKEYYTREYLGSYIIATSKFYFQDPEFCTPRDMLLGKYRAYDSLATYLDEKKFKIRNGLNGKLKSIKPIKKIHWPFSNTEYVELLYSLCSKGLGKQDNQGIMQVSKKLEQIFDFTPKDIYKTYHDIKNRKNSRTLFLDELSTSLLIEMDKSEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDG6</accession>
    <name>A0A5C6ZDG6_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HRDC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000029">
        <property type="protein sequence ID" value="TXD87116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010997">
        <property type="entry name" value="HRDC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002121">
        <property type="entry name" value="HRDC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044876">
        <property type="entry name" value="HRDC_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00570">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47819">
        <property type="entry name" value="SSF47819"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50967">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HRDC" evidence="1">
        <location>
            <begin position="1"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="57" mass="6503" checksum="D6C9846196866D74" modified="2019-11-13" version="1">MEKGLKTFHVFGNTTLHEMVNSKPKTKAELLDVKGIGERKLEQISDRVLEIIRKHAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDK4</accession>
    <name>A0A5C6ZDK4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Choice-of-anchor D domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044060">
        <property type="entry name" value="Bacterial_rp_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011467">
        <property type="entry name" value="DUF1573"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07610">
        <property type="entry name" value="DUF1573"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18998">
        <property type="entry name" value="Flg_new_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flg_new_2" evidence="1">
        <location>
            <begin position="163"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="Flg_new_2" evidence="1">
        <location>
            <begin position="235"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="2195" mass="234563" checksum="2A8E1B74E07D28DA" modified="2019-11-13" version="1">MKKKYTLVLVCFLCFVLSGFGQVTLPLVRTTWNSTPIGWTDSPLDSYTSSFACSTNNGAKFDTTGDVKIVYFEDTPNELKFVVKSNNLTSTSELLVEESTNGISYTTVINLAGTSNLPSSCTIKGPYNLNSNSRYVKWTFTKGSSNMTMDDVEITKATSTGPTITVTQATGGNISPDTASYAAGADQSFTATPDACHAFSNWIIDAATSSTANPYTFTNISANHTLTAVYNSYDYNITATSGPNGSITPSGITSVSCGANQSYTITAASGYAIDDVLVDGASLGAVSIYNFINVTAPRTISATFNVYVGPCLGEESFESGEPTGWTNNGSYYNTGDARSGNQKAGMNDLGDWIQMLSIDNPSSLVYYARLSSNPTGTNSVKIQYWSGTDWTDIIEHTATSEVYTIFTVDLSSLTSLINVQLRFFRSAHNRSIYIDDVSIFCGTPTPEPEIAIQGNGNEIVNGDSSPDSSDATYFGNVALAGGTQDNIFTINNTGTANLDITSVTSSNASEFMVSGATSGSISPSSSATFTVTFDPNAIGLSTATITVTSDDSDEGTYTFTISGNGTNSNLSTIIDNTNYGSTAPEFNSNPEYINFIDGSATSVGKFIPMKIRILDGPDADGFDTTLTNLSLTVEDVSNTNQLAMIKTALLTTTGGTVLATATKVANALVFSGMSGAAVTAPDDNLSGRILHIRASFDETQVVDRTKLIFKITSATADPTGSSFVAADAGGAQSSTGNNSQNRLNVTADRLSFVQQPSDTDTNATMTPAVLIEGIDMYAHRDLDYTTTIQIGSTGTMTSSPLSATAINGVASFNTIVHSVAENNRQLTAVRSGTLDWTATSSSFNITDLPTSNGDYRTTGSGNWNSNTIWERFTGGTWSSSTAPSYASVNRLYIRNGHTITTSGAFGSSVKLYILDGGTFINIHNSTAQQVFIYEGGTLDIRESLSIASSGTIEVFDGGMVYFDDRGNSNLTTSLWNGTENFHPLSELYITDFNPNAYLFNGEVTLNTYNGYTAAFGNVYVDYTNSVTGASPAEDWESVLGPNANDKNLCHNNFEFVSTRGNEKFQFIQNNDVVAGIGGDLILRSGIGSARRIVMATGNADLVLNINGNIELDCAGDFALRGGNSAAGSCTVNVDGNILVNGSNVTSNTQLRMNTTIYSIANGGMHIINLKGDLLITDAEIDNITPRDDVEFNFVGNTVQSVNIKSIVGNSSSEKGIPFYIKNGAKVLLTENNLRLNRSSLIKVESGGTLNFGFGLDGITPLLVTQPTSPSGSNLFELEEGGILKITHSQGISSLSTAGNVQLSASNKTFNQTATFHYIGKENQVTGNALLPGSSEKLVFVNLSNNSNTLILSNDVGISDATTLDLNGGKLEIQRGSVVGSSTGDFYGSGRLVMTNGEYRISTITASPLTDFLPRLGSTAGLPGIGGYANYELSGGIVNLDGSNATQILSGTPHYFNLKFSGTNDYGPPPFPILNYKGLSTATKVSNNITISNNAIVDVRNNSLGLGNNPSFTMNDSSRYVTDGGGEKPDTAGVYSLDINSTIEYANTTGAGIVRLGLSPIQYANIVISGTNVSNNSNVTGILLKNGGTFTVKDGATFKLKNTAGFSGAVNTAIRNTNSPTVTLEDFSTIEYTGTDQNITSFSPEYKNISISGTGTKTLGHPTDILVGEDLMVKSGSLLVKTDEAITVDERVIVDNTASFNIENSGSLIQINDTKTNIGKISMIRKASIKNLDYVYWSAPINGYNVSNISPTTHIYKWDATATNANNTQGNWIQAIGETMLPGKGYIVRAPNGQADPSPAGSLNFTTTFYDVGAGSSVPNNGEISIDIFRGDNTISDADTDDNWNLLGNPYPSAISIMDFLSQNLTVDGYVNLWKHGLPPNSSISPFYQNFSLNYNQSDYFYYNSSGSSDGPDSFSGFIAAGQGFMVNMVDGQLPDTTNVIFRNNMRDKAYVNNEFFRTSQNQMSSQEKHRIWLDLISPTTSTNRILVGYIEGATMPRDRMFDAPISFDAATEGIYSLINDESYIIQGRALAFDENDIIQLGIKVNAPENYTIAIGAVDGLFESNAQTIYLRDELLGFTHNLTNQPYSFTSEAGVFNDRFEIVFNPAALSTYQNEISAEGLLIMELKDGRVRFSVDKNLNIKNIEILDLLGRRLYNLKANNSSEIFELSNLSQSTYFAKATLSNGQVILKKAIKQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDT6</accession>
    <name>A0A5C6ZDT6_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pyridoxine 5'-phosphate synthase</fullName>
            <shortName evidence="2">PNP synthase</shortName>
            <ecNumber evidence="2">2.6.99.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pdxJ</name>
        <name evidence="3" type="ORF">ESY86_14690</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>1-deoxy-D-xylulose 5-phosphate + 3-amino-2-oxopropyl phosphate = H(+) + 2 H2O + phosphate + pyridoxine 5'-phosphate</text>
            <dbReference type="Rhea" id="RHEA:15265"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57279"/>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
            <dbReference type="ChEBI" id="CHEBI:58589"/>
            <dbReference type="EC" id="2.6.99.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; pyridoxine 5'-phosphate biosynthesis; pyridoxine 5'-phosphate from D-erythrose 4-phosphate: step 5/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homooctamer; tetramer of dimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PNP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.99.2" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00244">
        <property type="reaction ID" value="UER00313"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033856">
        <property type="term" value="F:pyridoxine 5'-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008615">
        <property type="term" value="P:pyridoxine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00003">
        <property type="entry name" value="PNPsynthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00279">
        <property type="entry name" value="PdxJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004569">
        <property type="entry name" value="PyrdxlP_synth_PdxJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036130">
        <property type="entry name" value="Pyridoxine-5'_phos_synth"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30456">
        <property type="entry name" value="PTHR30456"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03740">
        <property type="entry name" value="PdxJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63892">
        <property type="entry name" value="SSF63892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00559">
        <property type="entry name" value="pdxJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0664">Pyridoxine biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="3-amino-2-oxopropyl phosphate binding" evidence="2">
        <location>
            <begin position="213"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="43"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="70"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="190"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="7"/>
        </location>
        <ligand>
            <name>3-amino-2-oxopropyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57279"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>3-amino-2-oxopropyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57279"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>1-deoxy-D-xylulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>1-deoxy-D-xylulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>1-deoxy-D-xylulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>3-amino-2-oxopropyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57279"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="2">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="238" mass="26590" checksum="F1E2D3D45A9A5E35" modified="2019-11-13" version="1">MTKLSVNINKIATLRNSRGGDTPNVIQFAKDVQRFGAQGVTVHPRPDERHIRYQDVRDLKAEVYTEFNIEGNPIKSFMDLVLEIKPTQVTLVPDAEDAITSNAGWDTIKHKAFLTEVITEFKANGIRTSIFVDPILKMVENAKNTGADRIELYTEAYAEDYVNNREAAIKPYVDAAVLANGLGIGINAGHDLSLDNIEFFQKHIPNLLEVSIGHALIAESLYLGIENVVQMYLHRLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDV4</accession>
    <name>A0A5C6ZDV4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Dihydroorotase</fullName>
            <ecNumber evidence="7">3.5.2.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_13960</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.3" evidence="7"/>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004151">
        <property type="term" value="F:dihydroorotase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002195">
        <property type="entry name" value="Dihydroorotase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00483">
        <property type="entry name" value="DIHYDROOROTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="6">
        <location>
            <begin position="54"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD88200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="448" mass="49972" checksum="FC8E3395069754C4" modified="2019-11-13" version="1">MEGKTILIKNAKIVNEGKITEGDIYIEGDYIKEVATSISAKSSEVIIIDAEGNYVFPGVIDDQVHFREPGLTHKADIASESKAAIAGGITSYIEMPNTLPQTTTVEKLEEKFAIAAQSSFANYSFMFGGTNDNLDEILKVDPKTVAGLKLFLGSSTGNMLVDDPKVIEKIFSSTNMVISVHCEDEATIKKNLEAHIAKYGEDIPIEKHPIIRSEEACYISSSKAIELAKKTGARLHVFHLSTGKETKLFSNKLPLKDKKITSEVCIHHLWFSDEDYQKKGTHIKWNPAVKTPKDRDQLWKALLDNRIDVIASDHAPHTLEEKNNKYLNAPSGGPLVQHALVAMMEMHHKGKISVEKIVEKMCHNPAILFQVEKRGFIKAGYFADLVIVDANSPWSVNGQNILYKCGWSPFEGTTFKSRVTHTFLNGSLVYNNFKFMDVKAAKRLTFNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDW8</accession>
    <name>A0A5C6ZDW8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyl hydrolase family 17</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_16020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000021">
        <property type="protein sequence ID" value="TXD87684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000490">
        <property type="entry name" value="Glyco_hydro_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00332">
        <property type="entry name" value="Glyco_hydro_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="419" mass="47397" checksum="5BF8C3FEC559B9B1" modified="2019-11-13" version="1">MLCCLSCKEDAKEQNQSETVKEQENLTAKEILGNPDYPAISFGAYREKSLDIEPTLEELKEDMKLLSAMGIKIIRNYKVHLPEATNILKAISALKKEDPDFEMYVMLGAWIDCKNAWTDKPVDHNVESEANKPQIEKAVALANEYPDIVKVIAVGNEAMVKWAETYYVQPSVILKWVNHLQGLKKENKLPKDLWITSSDNFASWGGGDPLYHTEDLNKLIHAVDYISMHTYPMHDTHYNPSFWGVPKSEMRLSDEQKIEAAMLRAKNYAISQYNGVKNYMESLGVNKPIHIGETGWASSSNGLYGPNGSKACDEYKEALYYQHMRDWTDSAGLSCFYFEAFDEQWKDAENPGGSENHFGLFKINGQAKYVLWDLVDKGSFEGLTRNGNPIVKTHGGNKQELMKTVLVPPTAQEIAARLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDZ4</accession>
    <name>A0A5C6ZDZ4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_15205</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="61" mass="7074" checksum="7803A1E8F58F577B" modified="2019-11-13" version="1">MVETTRKWMLWIRSITYKIPFVGGRSFAIGNGACDFYIASSILHLDMRLWFFGLYLPGINV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE15</accession>
    <name>A0A5C6ZE15_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000025">
        <property type="protein sequence ID" value="TXD87385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="262"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="298"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="352" mass="38980" checksum="87901E249D4CF744" modified="2019-11-13" version="1">MLLTKYIKNKFSFFITFGFAFALFSCGSFQYVGYDNDGIYSDEEVNYEEAPVKTTTEVANNSYYRNYFAEKANQFADVPDAEPAVFTDIETYSSDYDQPYEDEAQVGYAGWGAANENVTINYYDTGWNNFGMGGFGMGGFGMGGFGWGGFGWDPFWGGNRWGFNNWGWGFNNWGWNQGWGWNQGFGNFGFNGGFHGIYNNGWNNHRGNYAYNAGRRGSRSNSNITRDYASSTRRSSSDVSRNATINRRSDNSSRSRATYDATRRTRSTISSPSRRSSGNDVRTRRSSQNEVRSRRSNNSRARSSAPSRSSTPSVNRSSRSSSSSARSGGSSSRSSGGSSRSSGGGSSRRGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEA0</accession>
    <name>A0A5C6ZEA0_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Guanylate kinase</fullName>
            <ecNumber evidence="2 9">2.7.4.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">GMP kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">gmk</name>
        <name evidence="11" type="ORF">ESY86_15280</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Essential for recycling GMP and indirectly, cGMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + GMP = ADP + GDP</text>
            <dbReference type="Rhea" id="RHEA:20780"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.8"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the guanylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.8" evidence="2 9"/>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004385">
        <property type="term" value="F:guanylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00328">
        <property type="entry name" value="Guanylate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008145">
        <property type="entry name" value="GK/Ca_channel_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008144">
        <property type="entry name" value="Guanylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017665">
        <property type="entry name" value="Guanylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020590">
        <property type="entry name" value="Guanylate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00625">
        <property type="entry name" value="Guanylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00072">
        <property type="entry name" value="GuKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03263">
        <property type="entry name" value="guanyl_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00856">
        <property type="entry name" value="GUANYLATE_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50052">
        <property type="entry name" value="GUANYLATE_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Guanylate kinase-like" evidence="10">
        <location>
            <begin position="4"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="11"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD87883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="192" mass="22015" checksum="1EBD9D230223ADBD" modified="2019-11-13" version="1">MKNGKLVVFSAPSGSGKTTIVRHLLEKEELNLEFSISATSREMREGEVDGKDYYFLDAHTFKQHIKNDDFLEWEEVYRDNFYGTLKTEVERIWANGKNVIFDIDVSGGLRIKRKFPKQTLAIFVKPPSIDELKIRLKKRQTESADKINMRIAKASAELATAPLFDTIVLNEHLENALIESYTLVSNFIADRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZED7</accession>
    <name>A0A5C6ZED7_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Na(+)-translocating NADH-quinone reductase subunit D</fullName>
            <shortName evidence="14">Na(+)-NQR subunit D</shortName>
            <shortName evidence="14">Na(+)-translocating NQR subunit D</shortName>
            <ecNumber evidence="14">7.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">NQR complex subunit D</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="14">NQR-1 subunit D</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">nqrD</name>
        <name evidence="15" type="ORF">ESY86_16510</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:47748"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="7.2.1.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="14">Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Cell membrane</location>
            <topology evidence="14">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the NqrDE/RnfAE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.1.1" evidence="14"/>
    <dbReference type="EMBL" id="VORO01000023">
        <property type="protein sequence ID" value="TXD87496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016655">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00428">
        <property type="entry name" value="NqrD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011292">
        <property type="entry name" value="NqrD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003667">
        <property type="entry name" value="NqrDE/RnfAE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30586:SF1">
        <property type="entry name" value="PTHR30586:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02508">
        <property type="entry name" value="Rnf-Nqr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006102">
        <property type="entry name" value="NQR_DE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01939">
        <property type="entry name" value="nqrD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="3 14" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 14" id="KW-0406">Ion transport</keyword>
    <keyword evidence="12 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 14" id="KW-0520">NAD</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 14" id="KW-0915">Sodium</keyword>
    <keyword evidence="13 14" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="6 14" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 14" id="KW-0813">Transport</keyword>
    <keyword evidence="11 14 15" id="KW-0830">Ubiquinone</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="101"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="185"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TXD87496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="214" mass="23037" checksum="4F5D333E148B5551" modified="2019-11-13" version="1">MGLLSKKDTKLITDPLADNNPITIQVLGICSALAITAELKASLVMGIAVLFVLGVGNVVISLMRNIIPSKIRIIVQLIVVASLVIIVDQVLKAYAYELSKTLSVFVGLIITNCIIMGRFEAFALGNGPWRSFLDGIGNALGYAVILVIVGFFRELLGSGTLFGIPVLGDAIEKTGVYSTGYENNGFMLMPPMALIIVGLLIWIQRSRNKNLIED</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEH9</accession>
    <name>A0A5C6ZEH9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_16230</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023041878" evidence="2">
        <location>
            <begin position="28"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="213" mass="23413" checksum="42DD0F6D24039B24" modified="2019-11-13" version="1">MKTIKQTQKMVAIFLTFVFLIPTVVSCSGENVQSNKVGDDYQKKAAKIFEAVDLVNQNFENLQMSKGTDYEITQELVDQYAVMLGYEAGEFDMVLVEEVVDKYADVLDRGYEQVLDDYALTSFAKITLVQIAEGNWIEDLENNPNYGNLSLTEKEMLSVANAYSQQSMQRLDAGPGIGAFIGLIVGGFICNVWCVLGGAIIGGIIGSSSKNDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEL3</accession>
    <name>A0A5C6ZEL3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PspC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_16200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="75" mass="9261" checksum="3106BEFC9ECDF396" modified="2019-11-13" version="1">MKWFYKMLYYSQKRGYYVCQRIADRLGIRAKVVRTTFMYLTFVTLGFGFTLYLFFAFWMRIKDIVYTKRSSVFDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEM7</accession>
    <name>A0A5C6ZEM7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_16345</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="224" mass="26016" checksum="F51907730E80F342" modified="2019-11-13" version="1">MDYHIIINDVKTVEQLDDAWNDQDYRALLSELGLEDTKDSKTQELWELLLMALSELEPNEAAALVLKYRMSDALNENQIEQLSHEMQLDKISEEYPNIGLHHELFNVNQLLFKAYNGTFPNAKATIVEFDMTPKQKNAEAVTKEHIVKAFDKTLYKGSVIKRLFSNHIAGEEAFDEAEDIIWTLEDKGNNHYKLVTSEYWMSKDDFTEAEFDAKVIEFEEEEVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEN2</accession>
    <name>A0A5C6ZEN2_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA-directed RNA polymerase subunit beta'</fullName>
            <shortName evidence="7">RNAP subunit beta'</shortName>
            <ecNumber evidence="7">2.7.7.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">RNA polymerase subunit beta'</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Transcriptase subunit beta'</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">rpoC</name>
        <name evidence="10" type="ORF">ESY86_16325</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7 8">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="7">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the RNA polymerase beta' chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="7"/>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01322">
        <property type="entry name" value="RNApol_bact_RpoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045867">
        <property type="entry name" value="DNA-dir_RpoC_beta_prime"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012754">
        <property type="entry name" value="DNA-dir_RpoC_beta_prime_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000722">
        <property type="entry name" value="RNA_pol_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006592">
        <property type="entry name" value="RNA_pol_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007080">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007066">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042102">
        <property type="entry name" value="RNA_pol_Rpb1_3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007083">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007081">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044893">
        <property type="entry name" value="RNA_pol_Rpb1_clamp_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038120">
        <property type="entry name" value="Rpb1_funnel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19376">
        <property type="entry name" value="PTHR19376"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04997">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00623">
        <property type="entry name" value="RNA_pol_Rpb1_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04983">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05000">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04998">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00663">
        <property type="entry name" value="RPOLA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02386">
        <property type="entry name" value="rpoC_TIGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 7 8" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 7 8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 7 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="RPOLA_N" evidence="9">
        <location>
            <begin position="252"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="477"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="479"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="481"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="825"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="899"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="906"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="909"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD87598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1433" mass="159722" checksum="42F2D02849A235C9" modified="2019-11-13" version="1">MARRQDKNTVQRFNKISIGLASPESVLAASRGEVLKPETINYRTHKPERDGLFCERIFGPVKDFECACGKYKRIRYKGIVCDRCGVEVTEKKVRRDRVGHINLVVPVAHIWYFRSLPNKIGYLLGLPSKRLDMIIYYERYVVIQPGDAKNVEGEPLQKLDFLTEEEYLNIMETIPQENRHLDDKDPNKFIAKMGAECLIDLLSRIDLNELSFELRHKANTETSKQRKTEALKRLQVVEAFRDSNLNRENKPEWMIMKAIPIIPPELRPLVPLDGGRFATSDLNDLYRRVIIRNNRLKRLVEIKAPEVILRNEKRMLQESVDSLFDNTRKASAVKTDSNRPLKSLSDSLKGKQGRFRQNLLGKRVDYSARSVIVVGPELKLFECGLPKNMAAELYKPFIIRKLIERGIVKTVKSAKKIIDRKEPVVWDILENVLKGHPVLLNRAPTLHRLGIQAFQPKLIEGKAIQLHPLVCTAFNADFDGDQMAVHLPLGPEAILEAQLLMLASHNILNPANGSPVTVPSQDMVLGLYYMTKLRVTTDEVKVKGEGLTFYSPEEVIIAYNEKQVELNAGIRVRTQDFNAEGELTTQIIETTVGRVLFNENVPAAAGYINEVLTKKSLREIIHGILKATSVPETATFLDEIKTLGYKYSFQGGLSFSLGDIIIPAEKQSMIDKANGLVDGIMANYNMGLITNNERYNQVIDIWTSTNAELTELSMKRIREDQQGFNSVYMMLDSGARGSKEQIRQLTGMRGLMAKPKKSNAGGGEIIENPILSNFKEGLSILEYFISTHGARKGLADTALKTADAGYLTRRLVDVSQDVIVYSEDCGTLRGIEVNALKKNEEIIENLEARIVGRTSLNDVFDPLTEELLVEAGGHIHDAIAKRIGQSALDGVEVRSPLTCEAKKGICSKCYGRNLATGKMVQRGEAVGVVAAQSIGEPGTQLTLRTFHVGGIAGNISEENKLTVKFNGVAEIEDLKTVKTKDNAGKDVDVVISRTSELKLVDAKTGITLSTNNIPYGSFIYVKSGDKVKKGDVVCSWDPYNGVIISEFAGKVKYENIEQGITYQVEIDEQTGFQEKVISESRNKKLIPTLIIEDAKGETIRSYNLPVGAHLMIDDGEKIKVGKILVKIPRKSAKAGDITGGLPRVTELFEARNPSNPAVVSEIDGVVSFGKIKRGNREIIVESKLGEVKKYLVKLSNQILVQENDYVKAGMPLSDGSITPNDILNIKGPAAVQQYLVNEVQEVYRLQGVKINDKHFEVVVRQMMRKVRIVDSGDTIFLEDQLAHKADFIEENDKIFGMKVVEDAGDSQTMKPGQILTTRALRDENSILRREDKALVTARDAQPATATPILQGITRASLQTKSFISAASFQETTKVLNEAAVNAKIDYLEGLKENVIVGHRIPAGTGVRKFENIIVGSKEEFNQMMKAKEEMNLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZES1</accession>
    <name>A0A5C6ZES1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cytochrome c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_14370</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13442">
        <property type="entry name" value="Cytochrome_CBB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome c" evidence="6">
        <location>
            <begin position="96"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="184"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="185"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD88069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="210" mass="23160" checksum="58EE572DD0B565C4" modified="2019-11-13" version="1">MKSLIKLITVVMIFVSVVACNSKSSRNYQYMPNMYESVGYEAYQEADVFDNNMEAQEPAEGTIPRGGHLPLGIAGDYDGYLEAKANLENPLDPKELEGSEGGQLYDIYCGICHGKKGNGKGILVEREKILGVPSFDDVGRAITEGSVYHVIYYGKNAMGSYKNQIDEKERWLVTDYVMQLKAELEGSSKDTKEDSAVNAETEKATDSVAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEU0</accession>
    <name>A0A5C6ZEU0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4231 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_13600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025325">
        <property type="entry name" value="DUF4231"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14015">
        <property type="entry name" value="DUF4231"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="139" mass="16452" checksum="297B99A012A4F548" modified="2019-11-13" version="1">MNQEEYIEQRLDNQIKWYSAKSATNQKKHKYWQVIKIISALLITTLSIVVDKFREITIVIGVLGAFVVFVESFVKIFDYEKLWLQYRTTSERLKREKLLFQTKSKPYHGEDSFALLVQQCEAIMQNEVQGWVELVGEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEV7</accession>
    <name>A0A5C6ZEV7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">SDR family oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_14535</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="271" mass="29423" checksum="7F2E5D086C036CDB" modified="2019-11-13" version="1">MDLKIKGKTALVTGGDSGLGIETAKFLARAGVNVIISDKTAGKDLDKAKAQVEKECEMGAKVMAIAADISNNDEVLALAKRIEDEFGGAHIIFHAAGARGAAGDFLELTDADWMKTIEIDLMGAVRVARAFVPQMQKLKWGRMILVASENAFQPYIEESPYNACKAAIINLAKCLSRAYSKENILINSISPAYIETPMTNAMMDELAEKRDTTVEKAVEWFVKNKRPHIAMQRRGRPEEVASVVAFLCSEHASFVNGANIRIDGGAVESAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEV9</accession>
    <name>A0A5C6ZEV9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cryptochrome/photolyase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_17315</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000026">
        <property type="protein sequence ID" value="TXD87320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036134">
        <property type="entry name" value="Crypto/Photolyase_FAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007357">
        <property type="entry name" value="PhrB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04244">
        <property type="entry name" value="DPRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48173">
        <property type="entry name" value="SSF48173"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="510" mass="60301" checksum="A87C1BBE6ED1D5C3" modified="2019-11-13" version="1">MKTLRLLLGDQLNSKHSWFKDANDDVTYCLFEMRQETDYDAHHIQKVIGFFAAMRQMASHLEEKGHKVVYFKINDAHNTQSLPKNLKLLLQEHKIEKFEYIAPDEFRLDEQLSHFCKELELASEVFSAEHFYTEREDLEKFYTGKKQYLMENFYRDMRKKHDILMEAGQPEGGKWNYDKSNRNKWKGDINIPNYKYYKNDVEAIVEDIATAEIKTIGHFGTKTFAYPIDRNQALDQLKYFCEQLLVRFGDFQDAMHTEQDYLFHSRLSFAMNLKIISPKDVVKTVMNYYRKNSDSIHISQVEGFVRQIIGWREYMRGMYWALMPEYKTKNALENHNKLPEFFWTGNTKMNCLKHAINNSLDNGYAHHIQRLMITGNYALLTQTNPDEVDAWYLGIYVDAIEWVQLTNTRGMSQFADGGKIATKPYVSSGSYINKMSNYCKDCHYKHTKKVEEDACPFNSLYWNFLDEKREFLGNNFRMGMMYSVLDKMKTADVNALKKRAQHIIAHQDEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF94</accession>
    <name>A0A5C6ZF94_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase family 4 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_16800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000024">
        <property type="protein sequence ID" value="TXD87438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="189"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="372" mass="41965" checksum="B58F6F23CCA473A7" modified="2019-11-13" version="1">MRLAIFTLVQHSFEDGHFYGYGPYVNEMNLWGRYVDELIVVGIKKPNNEVDAIDTPYKNKKITFVPVPNFNILGLLDVFKTSFKVPYIFFKCIQVMRQADHIHLRCPANVSLVACFAQIFFPYKKKSTKYAGNWDPNSKQPWSYRLQQAILRNTFLTRNMQVLVYGEWPHETSNIHPFISATYHESEKVAFSPKNYSDTLHFVFAGALVVGKRPLLTIQIMEALDQKGIPVKLHLYGDGPLMPELQAYLKSHKLEAIVNLYGNQDKSVVKAALMEAHFNILPSKSEGWPKAVAEGMFFGCIPIATPVSCVGWMLGDGTRGILIAPDLDAAVEAIVKALEQADLDAMAEAALDWSQQYTFDRLEADIAEVLIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFB2</accession>
    <name>A0A5C6ZFB2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_12000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="411" mass="48384" checksum="8E988B27DE01153B" modified="2019-11-13" version="1">MQKLKAAHLYRDELIPISGKLVERYNKCLKKLGLTETKLTNFSIDGIGWSPEIAMEKEESHYLCNGASNPHGIIISPIQQNKPVYMPYHTFDRDMMQLIFKNYADQIRDITRDSAICIDFDQKIDAFYEPLDVLKYHIIHINFHLMDNLYHQQQEQLQLIDTFKQGNNFIDEDLQGKILRSAQAYGDLRHRNLELPALDFSTSSFYTQAFGGVYVLRDFIAPIVIFQDLKWYKEAIKDTVHEVIIFHISQPELMAKLQDHLIISYDLEAIVKTKRYERIKKFMLAQYLKNTAHPIQVILNDSVLFKSYLNKLDLEPRKTVMSVERYLEKMETSNAFKISDIVDVDLFEALHEPHSSLPAKHQDLIWKLLVNVAPKDVLFLYWYDKQLFYKIYEPLDDSLKDWIIEIIKKNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFF1</accession>
    <name>A0A5C6ZFF1_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">30S ribosomal protein S17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 4" type="primary">rpsQ</name>
        <name evidence="4" type="ORF">ESY86_14875</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the universal ribosomal protein uS17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01345_B">
        <property type="entry name" value="Ribosomal_S17_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019984">
        <property type="entry name" value="Ribosomal_S17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000266">
        <property type="entry name" value="Ribosomal_S17/S11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10744">
        <property type="entry name" value="PTHR10744"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00366">
        <property type="entry name" value="Ribosomal_S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00973">
        <property type="entry name" value="RIBOSOMALS17"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03635">
        <property type="entry name" value="uS17_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 3" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD87950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="85" mass="9953" checksum="45E8C8C32B894D61" modified="2019-11-13" version="1">MEKRNLRKERIGVVTSNKMMKSIVVAEVKKVKHPMYGKFVLKTKKYVAHDETNDCNIGDTVKIMETRPMSKSKCWRLVEIIERAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFI3</accession>
    <name>A0A5C6ZFI3_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 7">3-dehydroquinate dehydratase</fullName>
            <shortName evidence="7">3-dehydroquinase</shortName>
            <ecNumber evidence="5 7">4.2.1.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Type II DHQase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 11" type="primary">aroQ</name>
        <name evidence="11" type="ORF">ESY86_11410</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes a trans-dehydration via an enolate intermediate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>3-dehydroquinate = 3-dehydroshikimate + H2O</text>
            <dbReference type="Rhea" id="RHEA:21096"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16630"/>
            <dbReference type="ChEBI" id="CHEBI:32364"/>
            <dbReference type="EC" id="4.2.1.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 3/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 7">Homododecamer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the type-II 3-dehydroquinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.10" evidence="5 7"/>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00086"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003855">
        <property type="term" value="F:3-dehydroquinate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00466">
        <property type="entry name" value="DHQase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.9100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00169">
        <property type="entry name" value="AroQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001874">
        <property type="entry name" value="DHquinase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018509">
        <property type="entry name" value="DHquinase_II_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036441">
        <property type="entry name" value="DHquinase_II_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21272">
        <property type="entry name" value="PTHR21272"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01220">
        <property type="entry name" value="DHquinase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001399">
        <property type="entry name" value="DHquinase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52304">
        <property type="entry name" value="SSF52304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01088">
        <property type="entry name" value="aroQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01029">
        <property type="entry name" value="DEHYDROQUINASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="6 7 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="7 9">
        <location>
            <begin position="99"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7 8">
        <location>
            <position position="23"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7 8">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7 10">
        <location>
            <position position="18"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001399-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001399-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001399-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD88838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="139" mass="15490" checksum="25304AC72417EADE" modified="2019-11-13" version="1">MKKLIIINGPNLNLLGKRETNIYGNMSFTDFFESIVKKFPDLHLEHFQSNIEGELIDKLQEVGFGYDGIILNAAAYTHTSIGIGDAVKAIETPVVEVHISNTFSREDFRHQSFISPNAQGIILGFGLQSYELAIQSFIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFN0</accession>
    <name>A0A5C6ZFN0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MarR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_16395</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01047">
        <property type="entry name" value="MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="153" mass="17652" checksum="8360E5870DC9CC95" modified="2019-11-13" version="1">MKDLNIRLKTVSELSVSKQAVINVFLTHTMFKTKLLDVLKPHDLSIEQFNVLRILRGQKGKPLNLQDVQDRMVSKMSNTTRLIDKLILKEFVNRDECPENRRKIELLISSEGLKKLEEIDTLVDQTETQMTSNLTKTELKQLNFLLTKLATTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFN7</accession>
    <name>A0A5C6ZFN7_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 4">Imidazolonepropionase</fullName>
            <ecNumber evidence="1 4">3.5.2.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Imidazolone-5-propionate hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">hutI</name>
        <name evidence="6" type="ORF">ESY86_11960</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>4-imidazolone-5-propanoate + H2O = N-formimidoyl-L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:23660"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58928"/>
            <dbReference type="ChEBI" id="CHEBI:77893"/>
            <dbReference type="EC" id="3.5.2.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="4">
            <name>Fe(3+)</name>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
        </cofactor>
        <text evidence="4">Binds 1 zinc or iron ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid degradation; L-histidine degradation into L-glutamate; N-formimidoyl-L-glutamate from L-histidine: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the metallo-dependent hydrolases superfamily. HutI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.7" evidence="1 4"/>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00379">
        <property type="reaction ID" value="UER00551"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050480">
        <property type="term" value="F:imidazolonepropionase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019556">
        <property type="term" value="P:histidine catabolic process to glutamate and formamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019557">
        <property type="term" value="P:histidine catabolic process to glutamate and formate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01296">
        <property type="entry name" value="Imidazolone-5PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00372">
        <property type="entry name" value="HutI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005920">
        <property type="entry name" value="HutI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42752">
        <property type="entry name" value="PTHR42752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01224">
        <property type="entry name" value="hutI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0369">Histidine metabolism</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="5">
        <location>
            <begin position="300"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>4-imidazolone-5-propanoate</name>
            <dbReference type="ChEBI" id="CHEBI:77893"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="150"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>4-imidazolone-5-propanoate</name>
            <dbReference type="ChEBI" id="CHEBI:77893"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="248"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>4-imidazolone-5-propanoate</name>
            <dbReference type="ChEBI" id="CHEBI:77893"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="322"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="324"/>
        </location>
        <ligand>
            <name>N-formimidoyl-L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:58928"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="326"/>
        </location>
        <ligand>
            <name>N-formimidoyl-L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:58928"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="327"/>
        </location>
        <ligand>
            <name>4-imidazolone-5-propanoate</name>
            <dbReference type="ChEBI" id="CHEBI:77893"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD88674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="411" mass="45087" checksum="1163D72FC2AF0BB3" modified="2019-11-13" version="1">MTILILNIKELIQTRETNVTIVKGADMKSLPILKNAYLLIDHDTIVEFGKMEDYINIEADETIDATGKIVMPAWCDSHSHIVYAGDRTQEFVDRINGLTYEDIANRGGGILNSAEKLQHATEDELYEQASNRLNTLIKMGTGALEIKSGYGLTVDAELKMLRVIKKLKREFPIKIKATLLAAHALPKAYKNNKVAYVDLIINEMIPKVCAEDLAEYIDVFCETGYFDLEDTQKILEAGKTHGLIPKIHVNQFNAFGGVALGVAYDALSVDHLEVMTSEDITALKGSNTMPVALPSCSYFLSIPYTPARAIIDAGLPLALATDYNPGSSPSGNMNFVLSTACIKMSMTPEEAINAATINGAYAMGISSQYGSICRGKKANLIITKPIPSYQYLPYSFGENCIERVIINGRII</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFP3</accession>
    <name>A0A5C6ZFP3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_12890</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039423">
        <property type="entry name" value="TonB-dep_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32552">
        <property type="entry name" value="PTHR32552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0798">TonB box</keyword>
    <feature type="domain" description="Plug" evidence="7">
        <location>
            <begin position="122"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="6">
        <location>
            <begin position="338"/>
            <end position="798"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD88410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="799" mass="88836" checksum="6D5A694CC6AF9B2B" modified="2019-11-13" version="1">MKKLFLFFILLAQVCYSQQSKDIGGTIVDSLGNPIAGATIVDKSDPTNGVVSDFDGEFVISVAESTKELEVSYLGFKTKVVTINGNFLNIILEEEASQLEGVTVQGFRSVASKARVRTQAIQSLPETTVAIDAATIEASGIDNIQSFTAQISNVTFTQAQQPGVNFLTVRGISQIRNAESPVAVVIDGMTLPDASAMNMSLYDIELLEFIKGPQGTLYGKNAIAGAVNIVTKDPTNKNKTKVMLTAGNGGLYGAGLSSSGAFTKDKFYYSVTGRYSSFDGLINNTFLNQKADFSEEVNFRGKLKYRFSPRWSAVFVQDNFKIEAGGNYYVTKTDLFDPSIPVLADDDYSNEPFGDVLGDSDLSNSLSSLKVEGSLSKAKFQSVTSFNATRRYYIGENDYSQYAFSKVSQTSDSDTFSQEFRLTSDYGEDSKFDYTVGTLYQNSNRYLNTSTFLNRTYYEGGFVDASAENANYSTDPLVGNDDDNTIETLAGFGFVDYKLTEKFTVSAGVRVDYDKLTNESRISNTSIENDITVWQPKFSLAYEFSETILGYANYGRGYRSGGFNSDETVKFGRTYEPEFTNNYELGLKTSFLNNRIIFNNAFYRIDFENQQQYTFIPVTPAVLGIYNFEESTITGFETELKFRATNYLDFFTSLGLNDGEIKKGVYNRLTNAAAFDYETSEEVDVSGNTSPFTIESTFQIGANANFELAEKSTLGFHVNVDSRGTQYWDPLEEYKQEPYTLVNARVNLKLNNFGVTVWSNNIFDTKFNTEFFPTAEFGFNNLRFPNTPTTVGIDLSYTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFQ3</accession>
    <name>A0A5C6ZFQ3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SAM-dependent DNA methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_11515</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022749">
        <property type="entry name" value="D12N6_MeTrfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003356">
        <property type="entry name" value="DNA_methylase_A-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12161">
        <property type="entry name" value="HsdM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02384">
        <property type="entry name" value="N6_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HsdM_N" evidence="2">
        <location>
            <begin position="9"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="N6_Mtase" evidence="1">
        <location>
            <begin position="177"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="795" mass="90956" checksum="C4FC1EF0F5AA6733" modified="2019-11-13" version="1">MNTTSHNKLVSFIWSIADDCLRDVYVRGKYRDVILPMVVLRRLDALLEPTKEAVLQELAFQRDEAKFTEWDENGLRDASGYVFYNTSKWTLQLLHDTATNSQQILLANFEDYLNGFSDNVKEIIDKFKLRSQVRHMAAKDVLLDVLEKFTSSHINLTPFEKEDPEGRKLPALTNLGMGYVFEELIRKFNEENNEEAGEHFTPREVIDLMTHIIFDPIKDTLPPVMTIYDPACGSGGMLTEAQNFIKDEEGVIKALGDVYLFGKEINDETYAICKSDMMIKGNDPENIRVGSTLSTDEFAGTSFDFMLSNPPYGKSWSSEQKYIKDGKDVIDPRFKIVLSDYWGVEEEVDATPRSSDGQLLFLMEMVSKMKSLSQSASGSRIASVHNGSSLFTGDAGGGESNIRRYIIENDWLEAIVQMPNNLFYNTGITTYIWILSNNKATQRKGKVQLIDAGQLFRKLRKNLGNKNCEFAPEHINEILKVYTEMQAVESEGENQIAAQVFDNEDFGYYKVTIERPKRLKAQFTEERIESLRYDRILQEPMQYAYETFGDSVYKDISLHAKAILDWCEQNDLNLSAANKKKLTKKETWKKHQHLLSLAKKLEVHFGDKVFSDYNAFENEVSQTIKSEKLDASAADKKAILNAVSWYDADAEKVIKKKEKLSGDKLQKLLQHLGCQETDLADFGFFPMGHTERSRSAKGEPASRGWYLTYETESDLRDTENVPLKESIHDYFLKEVKPHVAEAWINLDTTKIGYEISFNKYFYKHTPLRPIEAVTKDILELEQQSDGLIAEILNLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFS6</accession>
    <name>A0A5C6ZFS6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Beta-glucosidase BglX</fullName>
            <ecNumber evidence="6">3.2.1.21</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">bglX</name>
        <name evidence="6" type="ORF">ESY86_16110</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="6"/>
    <dbReference type="EMBL" id="VORO01000021">
        <property type="protein sequence ID" value="TXD87675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102483">
        <property type="term" value="F:scopolin beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019800">
        <property type="entry name" value="Glyco_hydro_3_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="SSF52279"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00775">
        <property type="entry name" value="GLYCOSYL_HYDROL_F3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022702801" evidence="4">
        <location>
            <begin position="20"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="domain" description="Fn3_like" evidence="5">
        <location>
            <begin position="681"/>
            <end position="750"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD87675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="761" mass="83470" checksum="8069F207CB139714" modified="2019-11-13" version="1">MNRPILTFTIILTFGLASAQSQKTNNPFQTKVDSILKLMTLEEKLGQLNLPSSGDITTGASQSSNVAKNIEEGKVGGLFNIKTVAKIREVQQIAMEKSRMKIPLLFGMDVIHGYETTFPIPLGLSATWDMDMIEKTARMAAQEATADGINWTFSPMTDISRDPRWGRVSEGSGEDVYLGSRIAEAMVKGYQGDDLTLNNTMLACVKHFALYGAPDAGRDYNTVDMSKIRMYNEYLGPYKAAVDAGVASVMAAFNEIDGVPATGNKWLLTDLLREDWGFNGFVVTDYTGIEEMMYHGIGDFQEVSARALKAGSDMDMVSEGFLTTLKKSYEEGKVSMADIDTAVGRILTAKYQIGLFDDPYKYCDLDRPAKEIFTPENRAFARKVSSESMVLLKNDNNLLPLKKSGTIALIGPLSNDALNMAGTWSVATKQEKSSPLLEGLKTVAGKNVTILQAKGSNVDYDLDYEKRVTMLGKEIPRDGRTDKQLLDEALAIAKKADVIVAALGETAEMSGESSSVTNLQIPQVQKDLLNALLKTGKPVVLVLFTGRPLAITEEDENVPAILNVWFPGSEAGLAISDVLFGDVNPSGKLTATFPMNVGQVPIFYNHKNTGRPLGNKEGKFEKFKSNYLDVRNEPLYPFGYGLSYTTFAYGNLKLTSNTLNANGTIEASVEVTNSGTYDGKEVVQLYIRDVVGSVTRPVKELKGFQKVLLKKGETKTISFSISEEDLKFYNNSLEFKAEPGTFQVFIGTDSNAELMQEFELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFU8</accession>
    <name>A0A5C6ZFU8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_15595</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="203" mass="22664" checksum="D2BDFBD003214407" modified="2019-11-13" version="1">MKNLKYVVGILCIGAIIASCGDNSNKGTNELKNTVEAVNDAKKVINDATSIQESEEELRKKIPLTKDQYRTWLPENLLDLSLTSTRLDIGQGNGICSATYGKGNRRIQVMIIDGAGERGPGNVSTYRMAVNMELNMENENSYTKSSEIAGIKVKEGYNKTADIYSLMMFYGERFAVDIKTHEIEHEQLEQMVEELNLEELSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFW5</accession>
    <name>A0A5C6ZFW5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF2071 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_12490</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023375">
        <property type="entry name" value="ADC_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018644">
        <property type="entry name" value="DUF2071"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39186">
        <property type="entry name" value="PTHR39186"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09844">
        <property type="entry name" value="DUF2071"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160104">
        <property type="entry name" value="SSF160104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="232" mass="27545" checksum="770BC0FEBE86C49A" modified="2019-11-13" version="1">MTFLNAYWRNLLFINYEVDPKILEPYLPKGTELDFYNGKCYVSMVGFMFMDVKVLGIKLYNHINFEEVNLRFYVKHNNKRGVVFIQEIVPKPLITLVANSLYHEHYTTSNMDHVWKETHDSLFFEYRWQVNNKWQSIAATTEKEAVPILENSEEQFIMEHYFGYTGHKNKTFQYEVLHPSWLHYKVKDFNSAMDFEANYGTDFEHLKYAKPTSVILAKGAEVSIKNKLTVHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFX1</accession>
    <name>A0A5C6ZFX1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_10700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="5"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="41"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD88953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="229" mass="24924" checksum="0321F7D35F905F05" modified="2019-11-13" version="1">MPKILKITGLEKTYTSGNRELTVLQNISFEVEKGQTFSIVGPSGSGKTTLLGLCAGLDNPNAGTVELCGQDLSRLNEDQRAQLRNKEVGFIFQNFQLLPTLTALENVSVPLELQGDKDATKKSMALLEKVGLADRYDHYPSQLSGGEQQRVALARAFANAPSILFADEPTGNLDEETGEKVIQLLFDLNTEAGTTLVIISHDLDLANRTQQILRLKGGQILTNQRTAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGF4</accession>
    <name>A0A5C6ZGF4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Arginine decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_08985</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008792">
        <property type="term" value="F:arginine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006527">
        <property type="term" value="P:arginine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008295">
        <property type="term" value="P:spermidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002985">
        <property type="entry name" value="Arg_decrbxlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022643">
        <property type="entry name" value="De-COase2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022644">
        <property type="entry name" value="De-COase2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43295">
        <property type="entry name" value="PTHR43295"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02784">
        <property type="entry name" value="Orn_Arg_deC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00278">
        <property type="entry name" value="Orn_DAP_Arg_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50621">
        <property type="entry name" value="SSF50621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orn_Arg_deC_N" evidence="2">
        <location>
            <begin position="60"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="Orn_DAP_Arg_deC" evidence="1">
        <location>
            <begin position="312"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="469" mass="54405" checksum="06848FBC9026A003" modified="2019-11-13" version="1">MNTKYIDLISQTFDFPQEEFKLEDKTLEFHGIDLMKLVEDYGAPLKFTYLPQISNNIHRAKKWFEKAIKDNGYEGKYNYCYCTKSSHFKHVLDEALKNDIHIETSSAFDIDIVEKLKSEGKITNDTYVISNGFKRAQYVTNIARLINNGHKNAIPIIDNMEEIELLSEEIKGKFKVGIRIASEEEPKFEFYTSRLGIGYKNIVPFYRNQIQDNEQVELKMLHFFINTGIRDNAYYWNELAKCLKLYTSLKKVCPSLDSLNIGGGFPIKNSLAYEFDYQYMVDEIIHQIKAVCEMEEVDVPDIFTEFGSFTVGESGGAIYEVLYQKQQNDREKWNMINSSFITTLPDTWAINKRFIMLPINRWYDSYERVLLGGLTCDSDDYYNSEQHMNAIYLPKYNKEKPLYIGFFNTGAYQETIGGFGGLQHCLIPSPKHILINKDKDGNITTEVFAEQQKSEDLLKILGYNTEAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGJ9</accession>
    <name>A0A5C6ZGJ9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Flotillin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_15155</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the band 7/mec-2 family. Flotillin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027705">
        <property type="entry name" value="Flotillin_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13806">
        <property type="entry name" value="PTHR13806"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="PHB" evidence="5">
        <location>
            <begin position="33"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="452"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD87811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="472" mass="51403" checksum="A744E3BA83C0676F" modified="2019-11-13" version="1">MNYLQAQGFDLGLPIAVIVAILFVFVFFIILIRRYKRCPSDRILVVYGKVGGGQSAKCIHGGAAFIVPVFQDYQFLNLTPISIEVNLVNALSKQNIRVNVPSRFTIGVSTEPGVMQNAAERLLGLGAQDVQDLAKEIIFGQLRLVVASMDIEEINNDRDKFLTNISKSVETELKKVGLKLINVNITDIVDESGYIEALGKEAAAHAINAARKSVAEKNRDGSIGEANAVQDQRSQVAAANAQAVEGENTAKIAVANSDSLRRQREAEAGRVAIASEKVQSAKALQESYAAEQEAETARAERERSSQMADIIIPAEIDKRKVEIDAEAEAERIRRRAKGEADAILFKAQAEAQGQFEVLTKQAQGLQEIVKAAGNNSKDAVLLLIADKLPELVRLQAEAIKNIKIDKVTVWDSGNNGENGKSSTANFLSGMYKSVPPLQEMFNMAGMDLPEYLKGKDKAETQAPNLPKQKEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGY4</accession>
    <name>A0A5C6ZGY4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_09255</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="63" mass="7553" checksum="F39AF9909EEE1E00" modified="2019-11-13" version="1">MKLLNFFQYVYLIFAILFIVDGFYSLGSDGSRAIISFIFAGLAIFMFFFRRRFKKKFENRKDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGZ3</accession>
    <name>A0A5C6ZGZ3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_13670</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="175" mass="19763" checksum="D3CE1563281BF7C2" modified="2019-11-13" version="1">MTKIIAYTQKLPIWHIALGILFIAGALIAFADLNIFGIVSLIFAYMLLKTEGSEIDLESKTYRKIISVLGVKIGKWQPLDQPEYISVFNTTEHITVRIVTAETTNSQPVILLNLFLQNNQKITVHRTEDAKEAFDVASHIADALNINLLDATEKGNFQWVDKDNYRTHGQILHVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH02</accession>
    <name>A0A5C6ZH02_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carbonic anhydrase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_13140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the beta-class carbonic anhydrase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001765">
        <property type="entry name" value="Carbonic_anhydrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036874">
        <property type="entry name" value="Carbonic_anhydrase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11002">
        <property type="entry name" value="PTHR11002"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00484">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00947">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53056">
        <property type="entry name" value="SSF53056"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="209" mass="22906" checksum="7CF4A3B631AB07A1" modified="2019-11-13" version="1">MKAHTKETQATMTPQKSLNYLKEGNQRFQNNLKANRNLLEQVNDTSDGQFPFATVLSCIDSRVSAELVFDQGLGDIFSVRIAGNFVNEDILGSMEFASKLAGTKLIVVLGHTSCGAIKGACDDAKLGNLTNMLAKITPAVNAVNEPTDKSLRNSKNIEFVDNVSKKNVILTLDKIRAQSPILKEMEDNNEINIVGGMYDINTGEVTFYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH81</accession>
    <name>A0A5C6ZH81_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">OmpA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_08095</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006664">
        <property type="entry name" value="OMP_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003367">
        <property type="entry name" value="Thrombospondin_3-like_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028974">
        <property type="entry name" value="TSP_type-3_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02412">
        <property type="entry name" value="TSP_3"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01021">
        <property type="entry name" value="OMPADOMAIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103647">
        <property type="entry name" value="SSF103647"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022731783" evidence="6">
        <location>
            <begin position="22"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="OmpA-like" evidence="7">
        <location>
            <begin position="340"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="284"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD89343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="454" mass="48830" checksum="9440AE92272F6982" modified="2019-11-13" version="1">MKNLSRLLLAMLLVFGFNANAQDENNPWKIFIGTNAVDPYPVGEDAPLGDYFDEFFNATDHYNILPSLSTISVSRYVGDGFVLSAAGSINEIDKIGDSSADDLSYYALDGTISYSFRNAFNGPSGWFDPYLGVGGGYTWIDEIGAGTLNGNLGINFWMSDNIALTAQTAYKHAFEDYLPKHWQHSLGLSIAFGGTDTDGDGIYDKDDACPDVPGLKAFNGCPDSDNDGIEDSKDECPNEAGLAEFNGCPDTDGDGVPDNKDECPTDAGLKALNGCPDADADGVADKDDKCPNEKGPAANEGCPWEDTDGDGVLNKDDKCPNEVGTVANNGCPEVEPTEEEMKELNEYARSILFETGKSSFQKETDGVLKAMVAILKEYPQANFLIEGHTDSVGAEQTNELLSDRRANAVMDYLVANGIAQDRLTAKGYGEANPIATNKTAAGRKNNRRVEVSLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHC5</accession>
    <name>A0A5C6ZHC5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Fumarate reductase/succinate dehydrogenase flavoprotein subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_07185</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.700.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003953">
        <property type="entry name" value="FAD-binding_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037099">
        <property type="entry name" value="Fum_R/Succ_DH_flav-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015939">
        <property type="entry name" value="Fum_Rdtase/Succ_DH_flav-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030664">
        <property type="entry name" value="SdhA/FrdA/AprA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011280">
        <property type="entry name" value="Succ_DH/Fum_Rdt_flav_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027477">
        <property type="entry name" value="Succ_DH/fumarate_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11632">
        <property type="entry name" value="PTHR11632"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11632:SF53">
        <property type="entry name" value="PTHR11632:SF53"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00890">
        <property type="entry name" value="FAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02910">
        <property type="entry name" value="Succ_DH_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46977">
        <property type="entry name" value="SSF46977"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56425">
        <property type="entry name" value="SSF56425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01811">
        <property type="entry name" value="sdhA_Bsu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_2" evidence="4">
        <location>
            <begin position="36"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="Succ_DH_flav_C" evidence="5">
        <location>
            <begin position="503"/>
            <end position="635"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00890"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD89562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="636" mass="71226" checksum="6248BB0CED93F95E" modified="2019-11-13" version="1">MKLDAKIPEGRLEDKWRNYQLKSQLINPANKKKLNIIVVGSGLAGAGAAATLAELGYDVKCFCYQDSARRAHSVAAQGGINAAKNYQHDGDSVYRMFHDTLKGGDFRSREANTYRLAELSSPLIDHFVQQGVPFAREYGGTLVNRSFGGVQVQRTFYARGQTGQQLLLAAYSQLYKMVKAKKVVMYPRSEMLDLVVINGKAKGIIVRDLVSGQLKRFAADAVVLATGGYSRVFRLSTLAIGCNGSALWKAHKKGAFFAAPSFTQIHPTALPQSSEAQSKLTLMSESLRNDGRIWVPQQQDDTRNANAIPDAERDYYLERKYPSFGNLAPRDIASRAAKERIDAGFGVGKLKNAVYLDFQHAIKKFGLDSIKDRYGNLFDMYHKITGIDAYQQPMMISPAAHFSMGGLWVDYELMTTIPGLYAIGECNFSDHGANRLGANSLLQASIDGYFILPNTINNYLATESKAPSYTCDHPEFEQTEREVQSHIKKILAINGSRTVDHFHRALGKIMWQECAMSRNKTGLEKAIEEIKDIKTAFWNDVKVTGASNELNTELEKALRLADFIELAQLMCKDALDREESCGAHFREEFQTHDGEALRKDDEYGYVSAWEYNDGHFKLHKEALEFEFVQPTVRSYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHD0</accession>
    <name>A0A5C6ZHD0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Putative toxin-antitoxin system toxin component, PIN family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_13400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002850">
        <property type="entry name" value="PIN_toxin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34610">
        <property type="entry name" value="PTHR34610"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13470">
        <property type="entry name" value="PIN_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00305">
        <property type="entry name" value="TIGR00305"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PINc" evidence="1">
        <location>
            <begin position="20"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="71" mass="7890" checksum="1EDC9B10DBB8E4E6" modified="2019-11-13" version="1">MAIIDRIERNSITIIPEISITACRDPKDNKFLELAVAAKASCIITGDDDLLVLHPFRSIPIFNPSDFLSSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHD8</accession>
    <name>A0A5C6ZHD8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_10180</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13174">
        <property type="entry name" value="TPR_6"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022828670" evidence="2">
        <location>
            <begin position="22"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="279"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="314"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="539"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="648"/>
            <end position="681"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1007" mass="115846" checksum="1C15CC104008262C" modified="2019-11-13" version="1">MAIRTIFFTLCFFMLNNFSFAQQSATYTNELVDYQKALTLYNNKQYQAAQSLFENIKEDAPNKTLESDCAYYIANCAVRLNQQNADALIEDFVNDYPTSTKRNTAFLDVADYYFANGKYAYARKWYDKVDENSIARSERDRFNFNYGYSLYATKDETAAQKYLNRVTTSTEYGSQAKYYIGFMAYEGDDYEKANTYFDQVSDQEKYKEKLSYYQADLNFKLGKFEEAIQLAKAQTVKGSPQEKSELSKIIGESYFNLQKYDEAIPYLKEYKGKKGKWNNTDYYQLGYAYYKQNDFEKAISEFNKIIGGDNSVAQNAYYHLGESYINLNKKQEALNAFRNASQMDYDLKIQEDAYLNYAKISYEIGNPYQSVPQVLTSYLTKYPNTQFKDEVETLLIDSYITSKNYKEALKLLENKNSFENRVAFQKVAFFRGIELYNEGDYNEARSFFEKAMKEAKTPIFTTRATFWKAETDFILSNFNDALIGFKQFAQNGEASEAEEFKNLDYNLGYTYFKLKNYSKSVTHFQSFVNSKTKDQLRLNDAYLRLADGHFVSSDYKDAIKAYEKAIALNKVEADYATFQKAVSYGFTGEGDTKMKELNAFIHNFPKSALRDDAMYELANSYIKTNQNDKALALYDRLNAEYPSSVFVSKALLRQGLSFYNSNDNEKALTKFKKVASDFPNTEDANQAVSTARLIYIDLGRVDEYATWVKTLDFVNVSDSELDNTAYLAAEKQYLDDNTDAAIKQFNKYINEFPNGIHATKSHFYLAELYNKKQLPENAKPHYEAVVKASRGEFTEQAIVKLSNIYLNKSEWKNAIALLKRLETEADYPQNVTYAQSNLMNAYYQLNDYNQAVTYAEKALQNSKIDNKVKSDAQIIIARSAIKTNNPSKAKDAYAKVEKIATGALAAEALYYNAYFKNKEADFEASNTAVQKLAKDYSSYKYYSAKGLVLMAKNFYALKDAFQATYILESVISNFTEFEEVVTEAQQELSKIKTEEAKTNASVQTEND</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHQ2</accession>
    <name>A0A5C6ZHQ2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4292 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07695</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025634">
        <property type="entry name" value="DUF4292"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029046">
        <property type="entry name" value="LolA/LolB/LppX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14125">
        <property type="entry name" value="DUF4292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89392">
        <property type="entry name" value="SSF89392"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022844736" evidence="1">
        <location>
            <begin position="21"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="260" mass="29910" checksum="D3C88306668C0ED4" modified="2019-11-13" version="1">MKKNKILSLGILMMMLVACKSPSLVSGDGKVNPEITAKQLIKENGRQEAKFNTLQAKVKINIIDNLNESGYTVNLRIEKDKTIWINASLGLARAMITPNKVQFYDRLNNQYFDGDYALLSDLLGVELNFEKVQNLLLGQPLFNLKNDTWEISNNESSYILQPKSQDPLLELFLLFNPSHFKMDSQQLAQKLKKRILQIDYTDYQKVDKETLPQQIKIYAVEDTEELIIELEYKSVSVNEEVRFPFNIPSGFKEINLDDVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHR9</accession>
    <name>A0A5C6ZHR9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_09635</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007492">
        <property type="entry name" value="LytTR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04397">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00850">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50930">
        <property type="entry name" value="HTH_LYTTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="5"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="HTH LytTR-type" evidence="3">
        <location>
            <begin position="132"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="233" mass="26955" checksum="BCE62FAD4CB4E689" modified="2019-11-13" version="1">MNFHKTIIIDDEPLAIDVITHHLKRFSNIEVIKTFTDSVEAFNFLKEGHKIDIVFTDIAMPEISGIELVKLSKGNTKFIITTSYSEYAVESFDLEVVDYLLKPISFERFCKAITRFEILENSENQKTLEPSFFVKEGDEFIKILVKDIDYIEGLKDYAKIFTGNNYCLALKTLKSIEAILSPYKFMRIHKSYIVPLSKISQYNGKCILVNNIEIPIGRNYKEALKIYLNNNKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHW4</accession>
    <name>A0A5C6ZHW4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Sec-independent protein translocase protein TatA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">tatA</name>
        <name evidence="9" type="ORF">ESY86_08020</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Forms a complex with TatC.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the TatA/E family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033281">
        <property type="term" value="C:TAT protein transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043953">
        <property type="term" value="P:protein transport by the Tat complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00236">
        <property type="entry name" value="TatA_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003369">
        <property type="entry name" value="TatA/B/E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006312">
        <property type="entry name" value="TatA/E"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02416">
        <property type="entry name" value="TatA_B_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01411">
        <property type="entry name" value="tatAE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0811">Translocation</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="46"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="55"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD89718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="81" mass="8828" checksum="174FEFD4A6BCBCBC" modified="2019-11-13" version="1">MTASSIFLAFGAWQIILIVIVVLLLFGGKKIPELMRGLGSGIKEFKDASKEEDENPSPTQAQSSTQTPTPSPVDKKEDRTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHX7</accession>
    <name>A0A5C6ZHX7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_06095</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="87" mass="10010" checksum="C3E34F0FC4F3228D" modified="2019-11-13" version="1">MHNFFRLSAVDKLLNRFYKGFFSTKTKDAKCNIELSRIIAIQIIGEIIRGDKNKYNGFELNLVVDDANRLKVIDHGNLKASLQITRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI09</accession>
    <name>A0A5C6ZI09_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">FtsX-like permease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_13385</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="287"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="331"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="373"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="422"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="679"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="728"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="762"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="7">
        <location>
            <begin position="20"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD88296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="799" mass="88241" checksum="D445B27184865C83" modified="2019-11-13" version="1">MIRNYFKIAWRNILANKLFTLLNIAGLAIGVCVCVILFSFVNKELSYDKMYSNSEDIYRVNMETSEAYDYETWATMPNAVGPAIVAEIPQVETMTRLIKDDFGATASLKIGDKNYTEDGLYLADASLFKMFDFKFLQGNSETAFSEPKSIVLSMSAKEKLFGAKEAMHKLITVNNSDTLQVSGIYADLPKNSVMDCAMVYNIMDSWMGTNVYWSNASYETYVQLQPNADVAEIEKRATALIDKNVDKDGQYFTKFIFQPLTKIHLYSADVREGYSTKLGNITTIKSLMFLSLLVLFIACINYMNLATANSRKRAKGIGVNKVLGANRRQMLFLFYVETGILVLVSIIVGYAASFLTLPLFQNVTSSELAFSDLLAAPILVGLLLIWIVVTIIAGSYPAIAMSGISPLILVNKSKKKNSASEYVRKGLVVFQFAASIVLIIAVTIILQQMAFIKNKNLGYDPNGIIAISVKSAENQQQIDAFTKAVEKHSNVESVSAVQAMPGVGESGRSVQKLVTDNVGLPIASCRTNGKVVKTLKLNLLAGNELPEHIAEGDSIIYTLINEKILSYLDYKTAEDAVGKIINTELGSRAIITGVVKNFNFSSLKEDVGGYMYYKSSSAPEGIRTLLVRYNTQKLPQFMGQLEKTFNENLPNTAFDYQFVDRHVAQLYASEEKTASTATIFSALAIFIACLGLFGLAAFMAEQRTKEIGVRKVLGATVANLTKLLTKDFLKLVLVAFVIAAPIAYWLMNKWLLDFAYRTEMSWWVFALAGLAAVLIALITVSFQAIKAAIANPVKSLRTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI45</accession>
    <name>A0A5C6ZI45_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_13620</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="226" mass="25928" checksum="7401B097BB7E3EBA" modified="2019-11-13" version="1">MKNYILTLIIGITLIGCSSDNETEPVQSSCNFINFKYYNGTQDLLGVMSNEYILIAVDTTYNESEIQNFITTIDVIDQNYNYTIQTSGQYKFKEIPLKLNTSKDCEEITQIISDLNQNTIISYVHFAMNTDDCNNLIWEPMGDLCINSYGSSFFVKVFDENDLTDLNQMIIETNTEMVEQNQFMEKWFELRATKESNGDGLAMANFFYESGLFEHSEAGISKYPVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIC8</accession>
    <name>A0A5C6ZIC8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UDP-N-acetylglucosamine 2-epimerase (Non-hydrolyzing)</fullName>
            <ecNumber evidence="3">5.1.3.14</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_09810</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UDP-N-acetylglucosamine 2-epimerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.14" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008761">
        <property type="term" value="F:UDP-N-acetylglucosamine 2-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003331">
        <property type="entry name" value="UDP_GlcNAc_Epimerase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029767">
        <property type="entry name" value="WecB-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43174">
        <property type="entry name" value="PTHR43174"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02350">
        <property type="entry name" value="Epimerase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00236">
        <property type="entry name" value="wecB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase_2" evidence="2">
        <location>
            <begin position="29"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="365" mass="41792" checksum="C17BF17C1818CEC5" modified="2019-11-13" version="1">MKKILIVVGTRPNYIKVTQFKKVAEHQFSGQFDIKIVHTGQHFDKSMADVFFQQLDIWPDYFLNISQASPNTQMGEIMIRLEKVITKEFQPDIILVPGDVNSTLAAALTAYKLGIPLGHLESGLRSFDRSMPEEVNRILVDEISDFYFVTEQSGIDNLLKEGKPDAKIHFVGNTMIDTLVAFEKPIREQQVMTDNGLEKDNFILMTIHRPATVDNREGLENLVTLFNRIPKNQNLVFPMHPRTLKNIDKFGLKNEFDAIENLKILKPLDYFSFQNLIHNCKMVLTDSGGIQEETTFKQKACLTLRPNTERPSTLEIGSNTLLNFDQDEILKQIERIISGTYKKGEIPKYWDGKATERILEVISEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIJ0</accession>
    <name>A0A5C6ZIJ0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_07145</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="61" mass="7132" checksum="2D65F41C2D36AAFC" modified="2019-11-13" version="1">MEITILKPRNAINKAFLKIKPNRTEIESFKTNLIQLLDRTNDTESEEFHKNLVTGFLNKTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIT0</accession>
    <name>A0A5C6ZIT0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_07685</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="150" mass="17172" checksum="8DC429574CC9D2EE" modified="2019-11-13" version="1">MGFFNNNLSLSGIITFEAVGGKHQHRLSGTFQNHADAKTRVGNPLTLLDFTRSTKLPLLVFFTNNHARVRLKLKLKRVFNRLWKVNLCPADIIKFGLLVENTNIGILELFRIMQTQKVSRISSNSKLLVENTASAFWIFSESRRRKKASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIU3</accession>
    <name>A0A5C6ZIU3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_08715</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011044">
        <property type="entry name" value="Quino_amine_DH_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011110">
        <property type="entry name" value="Reg_prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011123">
        <property type="entry name" value="Y_Y_Y"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07494">
        <property type="entry name" value="Reg_prop"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07495">
        <property type="entry name" value="Y_Y_Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50969">
        <property type="entry name" value="SSF50969"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="765"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="5">
        <location>
            <begin position="823"/>
            <end position="1036"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="6">
        <location>
            <begin position="1072"/>
            <end position="1187"/>
        </location>
    </feature>
    <feature type="domain" description="HTH araC/xylS-type" evidence="4">
        <location>
            <begin position="1219"/>
            <end position="1318"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="1120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD89452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1318" mass="150396" checksum="8A70D0C600A74A70" modified="2019-11-13" version="1">MKMACFLIGALFVIESNSQSQVSFRQLSVNDGLSQNSVVSVTQDSIGYLWLATQDGLNKFDGNKFQIYNAFFIDVTKPTYSHLGKVYTDREGNIISIPISKKPQIYNKKEDSFSPFSTLKDVSAVYQDRKKNYWFGTYNFGVFKMDGLTQKETLIIPPEDIGSIYSISEDSNGTIWLASQGKIVSVNSEDNTITPHFPDGNKNSTINYAAILFDASAAIWIGSYGNGLWFKDSKSPLFGRVDTLLQEEIELPDNLNILSMHIDKKNRLWIGTFGDGLYKMSLNTFEVTHFEVKKHNPRALHYNDILCIYEDYTGTLWFGTDGAGVSFYDEYLEKFNVINNSQIPEEVNIDLVRAIQVDKNDDVWIGTSGKGLSRYTPKTNLWKTYTEKAGSLSSNRIVSLLIDDDQDLWIGTQGGGLNIMQTNGETRYYNKNSTVALPTETIWDIFEDSSNATWLATRDHGMIQFDKNKGVLKTYDTSNGLPSNNVRVIIQGEDQKLWVGTEENGVLLIDPKTETFIDFQKDFNIEDENYVKKVKSLYYDQEGLLWVGTNGYGLSVFNFKNKTFHNYTIDDGLPNNVIYAILPDANNNLWLSSNRGITMITAPQDLNNKPVIANYDNYDGLATEFNTGAYFKSKNNVFYFGGLEGYYWFNPEDIQKNQVLPKTVITDFEVFNTSFPLVNNTELKYKQNTVSFTFSSLQFSLPKKNKYSYKLENYDENWIESKNSKTVRYTNLPFGSYTFLVKSSNYDGVWNEKPVSFSFSILKPWYLSSWMFFVYALLTLLISVLTYYYFKWKWKMTFNLKQEKQESGRLKRLDEYKTKLYTNLSHEFRTPLTLISGPIKKQLLTSDLKPDSKNDLQLVERNIDQMLSLVDQLLELSKLESGKMTLKVKQNDLGLYLKVLTESFQFLAEQHGLKLSAKIPDIEEAWFDADSIERIVNNLFSNAIKYTSKGGVIAFSAKRTDDNEIRMTFINDIDGIIEKDIYKIFNRFYQINEDSEGSGIGLSLVKELTSLCHGTIEASYVDASKMKFVVNLPITKNAFLPNEIDTATGFQSRASQTEMASSNTAENTKKPIALVVDDNQDIRAFIKSLLVENFRVIEAKDGFEGIEKAFKTIPDIIISDLVMPLKTGIELCEILKHDEKTSHIPIIILTGKTDEKDEIVGLNTGADDYITKPFNPKTLQIKVGNIIQNKNKLHQRYKQDNLFSPKEIAVTSADQVFLEKVQTILDQHLSNPEFTSEVFSKHVGMSRMQLHRKMLAYTGLSTSNFIRSQRLKQATSILKSSQFTINEVAYMVGFSTPSYFIKCFKEMYRQTPAEYTNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJB7</accession>
    <name>A0A5C6ZJB7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_03255</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="3"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="35"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="295" mass="32691" checksum="AA4A53D751ED7A1A" modified="2019-11-13" version="1">MKLVISNLTKTYKNGVKAIDDLNLEIGTGMFGLLGPNGAGKSSLMRTIATLQSPDSGSITFGDINVLEDKMALRKVLGYLPQSFGVYPKLSAEDLLDYFASLKGIGKKSDRQALVKEVLDITNLYEVRKKHVAGYSGGMKQRFGIAQLLLNSPKLIIVDEPTAGLDPAERHRFLNVLREVGTNCTVIFSTHIVEDVKELCNDMAILNGGRILKQATPSHARKELIGRIWTKLIDRDDLEANEAKYNLLSSNYNEDNTLNIRVFEDEMPGADFKAVEPQLDDVYFIALKQDEPVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJF8</accession>
    <name>A0A5C6ZJF8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PDZ domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_11045</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="2">
        <location>
            <begin position="274"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="478" mass="51831" checksum="AA76A49E1BD9A421" modified="2019-11-13" version="1">MKKFLILVFVSMLGGIIALSAYLFFFNATAPQAEQVSTADQPYFVPANYNGDAKTNALIHAESPNFVEAAENSIHAVVHVKNTSIVSNPATFQDLFYGRQSQPRTQVGTGSGVIISPDGHIITNNHVIAGSDKISITLNDNRVYEARLVGTDEKTDIALLKIDADEPLPSIQFGDSDTIKVGEWVLAVGNPFNLTSTVTAGIISAKARDLSGRNSQSFLQTDAAVNPGNSGGALVNARGQLIGINTAISSQTGSYIGYSFAVPSNIARKVVEDIIEFGDVQNGILGVSILNRNSKEAIDKGINQIDGVYVSNVEDKSGAKKAGIKEGDIIKKLDEITISKFSDLSGYLKTKRPNDVVNVEVLRDGTLKTISVKLSKTDIVSVDFIDMKLQNLPDLVKKKYNIKNGVMVTDTENAFLYKRLGITRGTVITGINDMAINNIEDLAHFKAQYGDDVIDNIEKLKYIDGSLKEKEVYFTENR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJG6</accession>
    <name>A0A5C6ZJG6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF2452 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_03525</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019534">
        <property type="entry name" value="DUF2452"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10504">
        <property type="entry name" value="DUF2452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="135" mass="15699" checksum="D572716955E2D47B" modified="2019-11-13" version="1">MSEKKKPDQVVFNESSQTYDAALKPYATNVGAPAIKATNTTTWKNKNIYKANKQIKAKYLELKAEFDKMTESLEYNNLVYSARFNFEPIIGETYHLYRDKNEEPFLSILAPNDCNFDFVGSFYLNSELLWKKIED</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJJ6</accession>
    <name>A0A5C6ZJJ6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_08885</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="215" mass="25049" checksum="4C9647371EA3E343" modified="2019-11-13" version="1">MRKNEGANPPCLVSLDWHQDLCYPCEVEKEWLHDLDLFSDGDVSIFSWTKLAGNNDGHILCAAYLNIIGDIYVHCRQEPFPDSWKDEELIDKLGNVHTIKIFKTYKDLQNALLSSSETSVFFDIDLDFFSVKNGLSDDSFIFSYLQEEEIRKMLDKDNPLIHWVFERLKGITIATEPEHCGGLLRSNKFLDLISDIYFDPELFAPKCNWKWKPKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJK5</accession>
    <name>A0A5C6ZJK5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Coproporphyrinogen-III oxidase</fullName>
            <ecNumber evidence="11">1.3.98.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">hemN</name>
        <name evidence="15" type="ORF">ESY86_11315</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>coproporphyrinogen III + 2 S-adenosyl-L-methionine = 2 5'-deoxyadenosine + 2 CO2 + 2 L-methionine + protoporphyrinogen IX</text>
            <dbReference type="Rhea" id="RHEA:15425"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:57307"/>
            <dbReference type="ChEBI" id="CHEBI:57309"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="1.3.98.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11 13">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="11 13">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; protoporphyrinogen-IX from coproporphyrinogen-III (AdoMet route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the anaerobic coproporphyrinogen-III oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.98.3" evidence="11"/>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00323"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051989">
        <property type="term" value="F:coproporphyrinogen dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004109">
        <property type="term" value="F:coproporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004558">
        <property type="entry name" value="Coprogen_oxidase_HemN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034505">
        <property type="entry name" value="Coproporphyrinogen-III_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13932">
        <property type="entry name" value="PTHR13932"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000167">
        <property type="entry name" value="HemN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00538">
        <property type="entry name" value="hemN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 13" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 11 13" id="KW-0408">Iron</keyword>
    <keyword evidence="9 11 13" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7 11 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10 11" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11 12" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="14">
        <location>
            <begin position="46"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="67"/>
            <end position="69"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="113"/>
            <end position="114"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="243"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="330"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR000167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000167-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR000167-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TXD88820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="454" mass="52229" checksum="E77BCD751C1101DB" modified="2019-11-13" version="1">MNKTLIKKYNIPGPRYTSYPTVPFWDLEAFTKDLWMKSFKRSFIESNSDQGISLYIHLPFCESLCTFCACHKHITKRHGMEDPYIKTVLKEWDLYVNEMPEKPVIKEIHLGGGTPTFFSSENLSLLIKGILEPSVLHADYEFSFEGHPNNTTKEQLQALYDLGFTRVSYGIQDYDPKVQAAIHRLQTFEQVEKVTQWSREIGYTSISHDLIFGLPFQTLDSIKNSIEKTKSLLPDRISFYSYAHVPWVKGVGQRGFDEADIPKDDEKRALYETGKQMFLDLGYEEIGMDHFALKSDQLYKAMKNQTLHRNFMGYTTNTTQLMIGLGMSAISDSWYGFAQNVKTVKEYEALVASGEIPVFKGHLLSEEDLIIRQHILNIMCQLETAWEEDRMAFPQLASVLDSLKEAENDGIVHMGNERLTIPEAAKPFIRNICMAFDLKLHQKQSETQIFSMTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJT1</accession>
    <name>A0A5C6ZJT1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="10">DEAD/DEAH box helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ESY86_06350</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Q_MOTIF" evidence="9">
        <location>
            <begin position="5"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="36"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="234"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="390"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="5">
        <location>
            <begin position="5"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD89822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="453" mass="51625" checksum="B2FBEA9F31BF7055" modified="2019-11-13" version="1">MEATTTFHDLNLNTPLYNALGDLGFEIPTPIQAQAFNVVASGKDVVGIAQTGTGKTFAYMLPILRHLKYSQQENPRILVLVPTRELVVQVVDEIGKLAAYTNVRVLGVYGGTNINTQKQAIAQGQDIIVATPGRLFDLALSHVLHLKSIQKLVIDEVDVMLDLGFRHQLLNIFDILPERRQNIMFSATMTEDVDALINEFFTKPEWVTVAVSGTPLHNIEQQRYEVANFYTKVNLLEHLLQDKDAFHRVLIFVAYKKMADKLFEALEAHFPDTVCVIHSNKTQNYRLRSIEQFRAGENRILIATDVMARGLDIENISHVINFDTPKYPENYMHRIGRTGRAELEGHALTFSTESEQEYIESIEEYMEKSIALLELPEAVEISKELIAEERPQIKEHNNPFKRIDDDSVGPAYHDKIDKNKKENLGGSYKFKIAAKYKKPKTRGDKNYNKRNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJU2</accession>
    <name>A0A5C6ZJU2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Class I SAM-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_04895</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="46"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="204" mass="23263" checksum="0BC9DA61A3F98A75" modified="2019-11-13" version="1">MRMNTKQHWDAVYGNKTPDQVSWTQEKPEISLQLIEATGLAKTAKIIDVGGGDSKLVDYLLEAGYQHITILDISAKALEKAKKRLGEKASKVRWIVSDISTFEPEETYDLWHDRAAFHFLTSKEEIEHYQAIASKCVRDSLIIGTFSKEGPTKCSGLEISQYDAVELSKVFENHFTKIECLSTNHETPFGTLQNFQFCRFRKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK11</accession>
    <name>A0A5C6ZK11_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_04030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="116" mass="12667" checksum="D9F1323F5C501957" modified="2019-11-13" version="1">MKNAINFIVTIIVALILSQFLPWWSIMVAGFVTALFFSLKRSAVFLVPFLAILLLWSVYCFWLSSGHDFIMAKKIAVLLPLDGNPYLLILVTGLIGGLAAGVAAILGKQCAVLIRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK57</accession>
    <name>A0A5C6ZK57_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">dTDP-4-dehydrorhamnose 3,5-epimerase</fullName>
            <ecNumber evidence="3">5.1.3.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Thymidine diphospho-4-keto-rhamnose 3,5-epimerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rfbC</name>
        <name evidence="4" type="ORF">ESY86_07985</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>dTDP-4-dehydro-6-deoxy-alpha-D-glucose = dTDP-4-dehydro-beta-L-rhamnose</text>
            <dbReference type="Rhea" id="RHEA:16969"/>
            <dbReference type="ChEBI" id="CHEBI:57649"/>
            <dbReference type="ChEBI" id="CHEBI:62830"/>
            <dbReference type="EC" id="5.1.3.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate biosynthesis; dTDP-L-rhamnose biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.13" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00124"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008830">
        <property type="term" value="F:dTDP-4-dehydrorhamnose 3,5-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019305">
        <property type="term" value="P:dTDP-rhamnose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000888">
        <property type="entry name" value="dTDP_sugar_isom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21047">
        <property type="entry name" value="PTHR21047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00908">
        <property type="entry name" value="dTDP_sugar_isom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01221">
        <property type="entry name" value="rmlC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="132"/>
        </location>
    </feature>
    <feature type="site" description="Participates in a stacking interaction with the thymidine ring of dTDP-4-oxo-6-deoxyglucose" evidence="2">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600888-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR600888-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU364069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="183" mass="20644" checksum="B7EE031A131BC1D0" modified="2019-11-13" version="1">MIAKETHLKDCFVIEPTVFEDARGYFFESFNKAKFLELTGLEVDFVQDNQSKSSKGVLRGLHLQTGDFAQAKLVRVIEGAVLDVCVDLRKDSDTYGQHLSVVLTAANKKQFFVPKGFAHGFVVLEDDTIFSYKCDEYYNKNSEAGIAYNDSTLNIDWQLPMETLILSEKDQALPSFKTYSDGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKC6</accession>
    <name>A0A5C6ZKC6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Rod shape-determining protein RodA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_05810</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001182">
        <property type="entry name" value="FtsW/RodA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011923">
        <property type="entry name" value="RodA/MrdB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30474">
        <property type="entry name" value="PTHR30474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30474:SF1">
        <property type="entry name" value="PTHR30474:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01098">
        <property type="entry name" value="FTSW_RODA_SPOVE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0133">Cell shape</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="149"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="189"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="234"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="331"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="364"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="397"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD90252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="426" mass="47825" checksum="31B9BEE795EAE9B8" modified="2019-11-13" version="1">MLRETDRDFKFDWITIILFLLLVGFGWLNIVSASHVGEIDSYFDITKLYGKHLVFIGLSTLLIVLILSLEAKFYERFATIIYIIAMLSLVGLFIFGKNVNGQLAWYGVGSMTIQPSEFAKFATALAIAKYMSDLQTNMKTLGDQIKAAGLILLPSILILLQNDTGSTLVYASFFFVFYREGLQKVYLTIAISAILLAVISLKFGILITAGSAAFVIFISYFFRRKKRAAFWKPIVLLLVCVGFSYGVELFYENSLQTHQRNRISLWLRLEKDPAKLEQMKKEEAYNLIQSEQAISSGGLSGKGFMEGTRTTGKFVPEQHTDYIFSTVGEEWGFLGSAIVIILFMALIIRVLVLAESQKSTFSRVYGYGVASILFVHFTINIGMVMGLIPTIGIPLPFFSYGGSGLWGFTILLFIFVKLDSNKINEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKC7</accession>
    <name>A0A5C6ZKC7_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 15 16">Protoporphyrinogen IX oxidase</fullName>
            <shortName evidence="15">PPO</shortName>
            <ecNumber evidence="15 16">1.3.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">ESY86_07465</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15 16">Catalyzes the oxidation of protoporphyrinogen IX to protoporphyrin IX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 15 16">
            <text>3 A + protoporphyrinogen IX = 3 AH2 + protoporphyrin IX</text>
            <dbReference type="Rhea" id="RHEA:62000"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:57306"/>
            <dbReference type="ChEBI" id="CHEBI:57307"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15 16">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
        <text evidence="15 16">Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 15 16">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; protoporphyrin-IX from protoporphyrinogen-IX: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 15">Cell membrane</location>
            <topology evidence="3 15">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 15 16">Belongs to the HemJ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.99.-" evidence="15 16"/>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00324"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070818">
        <property type="term" value="F:protoporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02239">
        <property type="entry name" value="HemJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005265">
        <property type="entry name" value="HemJ-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40255">
        <property type="entry name" value="PTHR40255"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03653">
        <property type="entry name" value="UPF0093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004638">
        <property type="entry name" value="UCP004638"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 15 16" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 15 16" id="KW-0349">Heme</keyword>
    <keyword evidence="13 15 16" id="KW-0408">Iron</keyword>
    <keyword evidence="14 15 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 15 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 15" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="57"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="89"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="127"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="15">
        <location>
            <position position="11"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="15">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00017504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR004638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="TXD89615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="182" mass="21643" checksum="2A3D2B553F43D230" modified="2019-11-13" version="1">MEYYNYIKSLHLIFIVTWFAGLFYIPRLFVYQIEASQKPSPEKEILGKQLKLMAKRLWNIITWPSAILATFFAIWLLILQPFWLQQSWMHVKLGFVVLLILYHLKTHQYYKQLQRDEVKKSSNFMRLWNEGATFILFAVVFLAILKNAINWIFGVVGILVLGILLMLGFKLYKRIRQQNPNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKD4</accession>
    <name>A0A5C6ZKD4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FUSC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_03570</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007237">
        <property type="entry name" value="CD20-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04103">
        <property type="entry name" value="CD20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="30"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="53"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="111" mass="12186" checksum="B2508B688FCA5A0B" modified="2019-11-13" version="1">MRHALLILGFIAAVLAVVLAVTPLSQMSFIPAVVALIAGIFAFYMDKDRSKKAVQLIFILTILSISLATYKGVFSSAEVGNTEELKQKEQQLENESIDELEDLDTEGLEIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKG8</accession>
    <name>A0A5C6ZKG8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltransf_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10115</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001077">
        <property type="entry name" value="O_MeTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00891">
        <property type="entry name" value="Methyltransf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransf_2" evidence="1">
        <location>
            <begin position="99"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="199" mass="22874" checksum="7D23455D0DEE6661" modified="2019-11-13" version="1">MSSKFDPRHILCHPFVYTTYQKLVGGHRARRLLIEQHVHIKPGQKLLDIGCAPADWLGCAPEVDYTIPNISPKRKKPPTIKANSFVRVLMVMNLPKMEHVEVIIVARVLHDVSDTQCLDLFETVGKVLEPGGRFITMDNCFISNQNEILEYFLKKDIDEHVKTKKDYELLINNDFEHVSSSIEETYFKIPNILIILSCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKJ1</accession>
    <name>A0A5C6ZKJ1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_06585</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="149" mass="16874" checksum="0D4DD61728231076" modified="2019-11-13" version="1">MKNTEFLLAFLAICFLTSCGLKPIASEYSFIKTDMGTVDLEGLGNGTVLIYNAADMLHKIDNTARLNVWIDEKPMGQIKPSEYVIINLKNGNHQFKLLHKDVVNMRSDHEVQVSDSTKVIRVKPNIASNKLEVTNELPLKFEKFKYAEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKL2</accession>
    <name>A0A5C6ZKL2_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cytokinin riboside 5'-monophosphate phosphoribohydrolase</fullName>
            <ecNumber evidence="1">3.2.2.n1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LOG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.n1" evidence="1"/>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009691">
        <property type="term" value="P:cytokinin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005269">
        <property type="entry name" value="LOG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031100">
        <property type="entry name" value="LOG_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03641">
        <property type="entry name" value="Lysine_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00730">
        <property type="entry name" value="TIGR00730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0203">Cytokinin biosynthesis</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="251" mass="28328" checksum="32F793B5BCBCD41F" modified="2019-11-13" version="1">MRQDQKEEEFLGGRRSRFKEFTSLLAIVIEFIHGFRKLHFVNPCITVFGSARFGEDNVYYKSASAFSQLAAQKGFTIMTGGGPGIMEAANRGAKDVSGKSIGCSIALPEEQEPNPYLDFNIAMEHFYVRKVLLLKYSYAFAVFPGGFGTMDELFETLTLLQTKKISNFPVVLFGKEYWSKLLEQTKVMQDIGTISKTDLDLFLVTDSVIEGMAYINTKLETTYGAPLLIRTTKSKWWLGEKEITAKKQKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKN6</accession>
    <name>A0A5C6ZKN6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_04140</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="577" mass="66946" checksum="5513C9EEAC19986B" modified="2019-11-13" version="1">MKKFCCILLLFYACSSEKKQATFDFNTKFESSNGTETATYEETINFYERLAETYPEINLKAMGSTDSGMPLHVVTVNADADFDFTEIRKNKRILLINNGIHPGEPDGIDATMLLFRDIVQGKIEMPKTTVLVTIPIYNVGGSLNRNPTSRTNQNGPKMYGFRGNARNFDLNRDFIKSDTKNARSFAEIYHLVKPDVFIDNHVSNGADYQYTLTHLFTQHNKLGGNLGTYLNEELMPGLEQKLTEKSWDVTPYVNVFNTVPEKGFSQFMDHPRYSTGYSTLWNSLGMMVETHMLKPYKQRVEGTYELMKSMIELTEKDGEKIAALRKAAFEAFKNQSSYPIQWEVDSSKRSTLQFKGYEGQMIKSTLTGADRLKYDRSKPFTKAVAYQNYFKPSLEVQIPKAYVIPQGWWQVIELLKINAIEMTQFKRDTSFSVSAYRIKDYDTRTAAYEGHYAHYDVNVETSEKEMSFRKGDYFISTQQDGIRYLLETLEPQATDSFFNWNFFDTILQQKEGFSPYVWEDMAAELLKKHPNLKAEFLQKKNKDQDFANNWYAQLDWLHKQSPNYEQAHLNYPVYRVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKT3</accession>
    <name>A0A5C6ZKT3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_06110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="180" mass="21255" checksum="4215393063878D7A" modified="2019-11-13" version="1">MKNITIFCLLLIFSACIPIRIAPKIKDHKLMVAKKFKRSLPRETAYIFSDPKDANEFYNYINTKFKLQDLDVGYNSPIKIGDKTYYLTYHETEIPNKTLNLPLIVADAALEKEGYPTLFENNHMRRVGNWYLVLTVYDEDIRNCLLKKHPDHQKILAYLNEMKTEYLQTSNYMETLFETK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKU3</accession>
    <name>A0A5C6ZKU3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Na+ dependent nucleoside transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">ESY86_02540</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005337">
        <property type="term" value="F:nucleoside transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008276">
        <property type="entry name" value="C_nuclsd_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011657">
        <property type="entry name" value="CNT_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002668">
        <property type="entry name" value="CNT_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011642">
        <property type="entry name" value="Gate_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10590">
        <property type="entry name" value="PTHR10590"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07670">
        <property type="entry name" value="Gate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07662">
        <property type="entry name" value="Nucleos_tra2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01773">
        <property type="entry name" value="Nucleos_tra2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022664307" evidence="7">
        <location>
            <begin position="21"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="145"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="205"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="231"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="267"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="309"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="343"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="409"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="459"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="525"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="562"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleos_tra2_N" evidence="8">
        <location>
            <begin position="150"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="Gate" evidence="10">
        <location>
            <begin position="235"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="domain" description="Nucleos_tra2_C" evidence="9">
        <location>
            <begin position="346"/>
            <end position="580"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD90857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="584" mass="62859" checksum="622D60E16820478C" modified="2019-11-13" version="1">MKHFLLAVTAIFFAINLNFAQELEKKWQIEAVKNDAGVNLYDIDSSDEFQLKNGNFNYDIKSADSLGEFSGNYLFQNTLLVLYYDTPTEKTERFNISELTDSTLVFANKEMSFSFKTPSKSSAPLMADGVNEGIVPSQGFSLGSLWRGLLGMVSLIFIAFLFSSNRKAINWKTVGIGLAFQLIIAVGVLKVEFIKSAFEVVGKGFIAILGFTQAGSEFLFGGILNVNSFGYIFAFQVLPTIIFFSALTSVLFYLGVIQKVVKGMGWLLSRVLGISGAESLSVAGNIFLGQTEAPLLIKAYLEKMNKSEILLVMIGGMATVAGAVLAAYIGFLGGEDEALQLFYAKHLLAASVMAAPGAIVISKILYPQTEPVDTDVHVSQEKIGSNILEAIANGTTEGLKLAVNVGAMLLVFVAFIAMFNGIIGGIASFDGFTIGVLNIDWHFTSLNQVIADNTPYDSLSLEFILGYLFAPLMWLIGIAREDMALMGQLLGIKLAASEFIGYIQLSDLKNVANPIHLKYEKSVIMATYMLCGFANFASIGIQIGGIGSLAPGQRKTLSKFGMKALIGGTIASLISATIAGMIIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKY7</accession>
    <name>A0A5C6ZKY7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">T9SS type A sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_02825</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008964">
        <property type="entry name" value="Invasin/intimin_cell_adhesion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49373">
        <property type="entry name" value="SSF49373"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022826494" evidence="1">
        <location>
            <begin position="20"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="domain" description="Aamy" evidence="2">
        <location>
            <begin position="389"/>
            <end position="757"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="947" mass="105471" checksum="C2B9410C8DC5A1AD" modified="2019-11-13" version="1">MKKLLQLLCFAGCLFPLGAQTITTDPAFFDETEEIEIIVSDFNPQTAWGVSDLYLWAWHFDENGNPINNPTATGTDFGNSPETAKFTSNMDGTYSYTLTPTTFYNNTNISRIAFLVKSQDGTSQTDDIIKAVGRVQVNINNPSSNLVLVNSGANIPISASINFQGTTTVQGTFEVFYNDVSVATGSCGFPACNTTLSNITESGTVRFVGTPPGSTETGETSFEVLVTPEVVAQALPSSLQDGINYGSDQTTATLVLTAPGKDFVHIAGSFNNYTPTNSDVMKRDPNTGKYWLQINGLTPGQIETYQYWAYDATPIANSKTLVKVADPFSTLVLSPFDDPFIPSNTYPNIPTYPAGQNFEVTVLQTGQTPYNWQVDDFNAPKEEDLIVYEVLVRDFDADRNYQDLIDRIDYFKNLNINAIQLMPVMEYEGNESWGYNTSFHMALDKFYGTEDKFKELIDLCHQNGIAVILDVALNHAFGRNPLVRLWVNDPEGDGFGNPSSENPYFNETARHSYNVGSDFNHQSPLTQEYTKRVVKHWVEDFKIDGFRWDLTKGFTQNCTGSDEGCTNGYQQDRIDILREYADYSWSLDEDHYVIFEHLGSQNEEKEWANYRLDEGKGIMMWGKMTDPYSQLLMGFNTNNNINAIGHKSRSQFNGPRVIGYPESHDEERLMYRAVTFGNDSNGSHNVQDLNTALSRMSAIGAMTITVPGPKMLWHFADLGMDNSIFTCNDGSINDDGCKLDTKPQPQWTENWLADANRNKIYNDWARLNALKINEPVFEGDYAMTTGTLTPRIDVFDTSLPTTALRNVIVLANFDVVSQTLNTNFPTSGTWYDLMDETGDTTHSAATITIPAGQFRIFGNQASTLSSASIAAENNFSIYPNPANSSFQTNKAINNLDIYDLTGKLIKSFKGDFSASERFDISDLTQSIYLVKIETNTGATLTSKLIKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL26</accession>
    <name>A0A5C6ZL26_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 3">Nucleoside diphosphate kinase</fullName>
            <shortName evidence="1">NDK</shortName>
            <shortName evidence="1">NDP kinase</shortName>
            <ecNumber evidence="1 3">2.7.4.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Nucleoside-2-P kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ndk</name>
        <name evidence="5" type="ORF">ESY86_04020</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>a 2'-deoxyribonucleoside 5'-diphosphate + ATP = a 2'-deoxyribonucleoside 5'-triphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:44640"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:73316"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a ribonucleoside 5'-diphosphate + ATP = a ribonucleoside 5'-triphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:18113"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the NDK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.6" evidence="1 3"/>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004550">
        <property type="term" value="F:nucleoside diphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006241">
        <property type="term" value="P:CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006183">
        <property type="term" value="P:GTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006165">
        <property type="term" value="P:nucleoside diphosphate phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006228">
        <property type="term" value="P:UTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.141">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00451">
        <property type="entry name" value="NDP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034907">
        <property type="entry name" value="NDK-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036850">
        <property type="entry name" value="NDK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001564">
        <property type="entry name" value="Nucleoside_diP_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023005">
        <property type="entry name" value="Nucleoside_diP_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00334">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01243">
        <property type="entry name" value="NUCDPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00562">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54919">
        <property type="entry name" value="SSF54919"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00469">
        <property type="entry name" value="NDP_KINASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 3 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NDK" evidence="4">
        <location>
            <begin position="3"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="active site" description="Pros-phosphohistidine intermediate" evidence="1">
        <location>
            <position position="117"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="11"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="139" mass="15296" checksum="0168ED214C367A98" modified="2019-11-13" version="1">MATNRTFTMLKPDSVEKGNVGAILEKITASGFRIVAMKLTHMTLRDAQEFYAIHKERPFFGELVEYMTRGPIVAAILEKENAVDDFRALIGATNPEDAAEGTIRKLYAASIGENAVHGSDSNENAAIESAFHFSGREQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL83</accession>
    <name>A0A5C6ZL83_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_04335</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="8"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="73" mass="8413" checksum="F004A0383A0A2600" modified="2019-11-13" version="1">MEELADFVKTRRKEVNLTQEEFADRAGVALTVVRKIEQNKTNLNLDKVNQVLKMFGHKLVPISLKNIKEDETS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL92</accession>
    <name>A0A5C6ZL92_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Shikimate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03405</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004764">
        <property type="term" value="F:shikimate 3-dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013708">
        <property type="entry name" value="Shikimate_DH-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022893">
        <property type="entry name" value="Shikimate_DH_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21089">
        <property type="entry name" value="PTHR21089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08501">
        <property type="entry name" value="Shikimate_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Shikimate_dh_N" evidence="1">
        <location>
            <begin position="6"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="245" mass="27658" checksum="90B33EE599E4400F" modified="2019-11-13" version="1">MRRLGLLGKNIEYSFSRGYFTKKFTAENLAFRYENFDLESISQFPELIKSNPDIVAMNVTIPYKEQVMPYLDEIDAEATKIGAVNTISISENGHLKGYNTDYHGFKTAISPLLKPHHKNALILGTGGASKAIAHALKTMHIAFDYVSRTKKQGVAYTYDQLDDLIIERYQIIINCTPIGTFPKIEACPDIPYQALNAEHLLFDLIYNPSETEFLRLGKAQGATTCNGYAMLEYQAEKAWEIWALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLB2</accession>
    <name>A0A5C6ZLB2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">TlpA family protein disulfide reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_02340</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013740">
        <property type="entry name" value="Redoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08534">
        <property type="entry name" value="Redoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="86"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="222" mass="25622" checksum="A862A8B29FE66C90" modified="2019-11-13" version="1">MIKTILITLSIISLLSCKTEQKKEIFYQAPNGKIFSSEKYEEVKLKLSQRGAIHEAILSTVERNDSIINLFETTVKEVNPYSEMENFIGKKLPFENLMDIDGDTLNIESLNGKPTLVNLWFVNCPPCVEEIPHLNELKEHYGDRVNFLAVTFDKKKQVEDFLLNRTFHFTHSIDAQIEMDKLNTKSYPLNIYLDKNGIIQSYQGSLSKDLDRGMKKELDKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLC6</accession>
    <name>A0A5C6ZLC6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ABC transporter ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_00295</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="161" mass="18736" checksum="A8A87D192C6B2F8C" modified="2019-11-13" version="1">MLVDFDTLPEESRVWIYQANRSFSDEELEEIKQKLDIFIAQWTAHGSDLQAAYKIEYKRFIVLALNQSLNKATGCSIDASVNFIQQLEQEYSVDLMDKMNVSYKQGEFVAHKTLLDFKQMAKDKAVSKNTIVFNNLVTNIAEFRENWEVPASESWHARFIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLM6</accession>
    <name>A0A5C6ZLM6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_05175</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="166" mass="18746" checksum="4BECFD5232511AA5" modified="2019-11-13" version="1">MRSANYNIKEKQIYFKVYQDLPQLENALKHLEEQRFLQVQVSVLGKSEQFHVDKNTAISKDTDTIKTYWESRLGNTMNFGTFYNPQTGSVFIVGSLVSTFLHKINGKSLATLSSGPYGVFRGIGASEAQATHCLKQLNDGNYVLILRGFEQELQAFDALSCRPIDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLP6</accession>
    <name>A0A5C6ZLP6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NADP-dependent glyceraldehyde-3-phosphate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_02265</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="2">
        <location>
            <begin position="37"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="525" mass="58422" checksum="FE4C5CD5C244349A" modified="2019-11-13" version="1">MTIPEKFQIKSEIKQDTYLINGELRPWTGESSEVYSSISSTKDYKPTLLGTIPTLGETEALEALDAAVNAYDKGQGLWPTMKVKDRIICMEKFVIQMKTKRDEVVKLLMWEIGKSLPDSEKEFDRTVDYIYNTIEEYKQLDRDNAKFEKHDGVRAHIRRGPLGVVLCLGPYNYPLNETFALLIPALIMGNTAIFKPAKFGVLLISPLLEAFRSSFPKGVVNIIYGRGRTVASPIMKTGKVDVLALIGNSKSANALQNQHPKSNRLRLVLGLEAKNPAIVLKDADLDLAIDECISGTTSFNGQRCTALKIVYVHEDIVEEFNKRFSAKVDALKFGNPWDDGVKLTPLPEPDKPAYIQELIDDALEKGAKILNEKGGKTTDNYIYPAVLYPVTKDMRVFQEEQFGPVIPVLSFSDIDKPLDDMAASNYGQQVSLFGSDVKTLAPLIDALVNLVCRVNLNSSCQRGPDVYPFTGRKDSAVGTLSVYDALRSFSIRTFVASKDNDYNNAILENLLDSKASNFVSTDYLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM00</accession>
    <name>A0A5C6ZM00_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_07065</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038461">
        <property type="entry name" value="Schlafen_AlbA_2_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="80" mass="9281" checksum="73F249E5764F52F3" modified="2019-11-13" version="1">MNTELEKIIRYDSEGPNLDYKQEEYPLGRNIKKNEILKDISAFANHHSDSDKFIIIGVKEKNGVGKEFFEIENLTDEASY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM08</accession>
    <name>A0A5C6ZM08_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">3-oxoadipyl-CoA thiolase</fullName>
            <ecNumber evidence="4">2.3.1.174</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">pcaF</name>
        <name evidence="10" type="ORF">ESY86_01895</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetyl-CoA + succinyl-CoA = 3-oxoadipyl-CoA + CoA</text>
            <dbReference type="Rhea" id="RHEA:19481"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:57348"/>
            <dbReference type="EC" id="2.3.1.174"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Aromatic compound metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.174" evidence="4"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00332"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033812">
        <property type="term" value="F:3-oxoadipyl-CoA thiolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019619">
        <property type="term" value="P:3,4-dihydroxybenzoate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012793">
        <property type="entry name" value="PcaF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020610">
        <property type="entry name" value="Thiolase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02430">
        <property type="entry name" value="pcaF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00098">
        <property type="entry name" value="THIOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00099">
        <property type="entry name" value="THIOLASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase_N" evidence="8">
        <location>
            <begin position="4"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase_C" evidence="9">
        <location>
            <begin position="276"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="6">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="357"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD90738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="403" mass="43220" checksum="EA2781DE98BEED64" modified="2019-11-13" version="1">MEAYIIDGIRTPIGNYKGTLSTVRTDDLAALVIAEIVKRNPNIPPEAYDDVIMGCANQAGEDNRNVARMASLLAGLPFTVPGETVNRLCSSGLSAMIHANRAIKAGDGDVFISGGVENMTRGPYVMSKPSTGFGGDSKMYDSTFGWRFINPKMEKMYGTDGMGTTAENLVEKYKISREDQDKFAYWSQMKATKAQENGRLAKEIMTVEIPQRKKDPIQFSKDEFVKPKTSLEILGKLRPAFKKENGSVTAGNSSGLNDGAAATIIASEAAIKKYNLTPLARIVSSAVVGVEPRVMGIGPVEASNKALKKAGLTMADMDVIELNEAFAAQALACTRAWGIADDDPRLNPNGGSIAIGHPLGVTGARLTYSAAIELKEQNKRYALVTMCIGVGQGYACVIENANF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM70</accession>
    <name>A0A5C6ZM70_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Steroid delta-isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03735</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12680">
        <property type="entry name" value="SnoaL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="305"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="404" mass="46256" checksum="A35336913C25E7CC" modified="2019-11-13" version="1">MNHYFTTLVFTILGFVSQAQPDTDVYLFDMSFEKDSLMLSNLKNISDQSGYDNQPSFLDDSHVLFTATRNGQTDICSYNLDDATKIWLTNTESSEYSPLKIPFQNAISAVRLEKDGTQYLVRYPISKDEPPTVLIDDIVIGYHLWLNRHILISSIIKDENLSLTVSDFRFTKHKDLIDNVGRSLSKIPSEKDENNFSFIDKNTKSWQVMSFDLEKLKAKVLFEMLPEVEDLVWLNEDLVLAGKGATLYLHNLRKRSDWQPVASLEHLGLSNITRLAISPNGKKLAIVAEKIQDIDKKTPELIVLQQLEAYNNRDIEAFLNCYSDDVRLYNFPKELISEGKEALREQFGNMFESITDLHAEIENRTIIGNTVIDKEKVRANGKTHEAVAIYEIENGLITRVTFLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMC4</accession>
    <name>A0A5C6ZMC4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">OmpA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_03080</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006664">
        <property type="entry name" value="OMP_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01021">
        <property type="entry name" value="OMPADOMAIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OmpA-like" evidence="4">
        <location>
            <begin position="228"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="165"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="337" mass="38735" checksum="FCAA38BCA0BBBBEC" modified="2019-11-13" version="1">MLKINTTATIKAIVLSVGMLFSVGLFAQSEKSSEEKISDESIIVMTKSELNSFLSTIAEARRSQLQERESRRVKEDLAELRLKYQERPGMQTGGYNTISNQQILRELQYLNQRIDNLSSYNNKMPSMNRDNSTIIMPSNAAPSQPYPLNDRSSTTVIPTSNNKKIKQLEAQIDSLKLAEANKANLQRENSFVDSLTMMKDRIKNVRRQMDSLDRKIIDAEKFAKPEKTTEDKSYFKQQIYFDNNSETLRGDYFPYIQEMTQILIKYPETKVMLEGWASTVGKADYNKQLSMRRAEAVEKALLNNRIDASRIITSFRGEDKVSSDQYARRVDMSIIVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMD7</accession>
    <name>A0A5C6ZMD7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF4442 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_01215</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027961">
        <property type="entry name" value="DUF4442"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14539">
        <property type="entry name" value="DUF4442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="151" mass="16781" checksum="83EE5225DC64A756" modified="2019-11-13" version="1">MTISPTKLNRFLMLKLPAAYLCGVRTKFLNETTCVVAVTHRWINQNPFNSMFWAVQGMAAELSTGALVMTKIRQSDHEISMLVANNRASFSKKATGKITFTCNAGKAIDEAIVKAVDTKEGQTVWLSSKGINEEGLEVSDFSFEWTLKLRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMF4</accession>
    <name>A0A5C6ZMF4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Diadenylate cyclase</fullName>
            <shortName evidence="10">DAC</shortName>
            <ecNumber evidence="10">2.7.7.85</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Cyclic-di-AMP synthase</fullName>
            <shortName evidence="10">c-di-AMP synthase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">dacA</name>
        <name evidence="12" type="ORF">ESY86_04255</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>2 ATP = 3',3'-c-di-AMP + 2 diphosphate</text>
            <dbReference type="Rhea" id="RHEA:35655"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:71500"/>
            <dbReference type="EC" id="2.7.7.85"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Probably a homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the adenylate cyclase family. DacA/CdaA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.85" evidence="10"/>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106408">
        <property type="term" value="F:diadenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006171">
        <property type="term" value="P:cAMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019932">
        <property type="term" value="P:second-messenger-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1700.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01499">
        <property type="entry name" value="DacA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014046">
        <property type="entry name" value="C-di-AMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034701">
        <property type="entry name" value="CdaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045585">
        <property type="entry name" value="CdaA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036888">
        <property type="entry name" value="DNA_integrity_DisA_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003390">
        <property type="entry name" value="DNA_integrity_scan_DisA_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19293">
        <property type="entry name" value="CdaA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02457">
        <property type="entry name" value="DAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004793">
        <property type="entry name" value="UCP004793"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143597">
        <property type="entry name" value="SSF143597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00159">
        <property type="entry name" value="TIGR00159"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51794">
        <property type="entry name" value="DAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 10" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="DAC" evidence="11">
        <location>
            <begin position="81"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TXD90587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="260" mass="29398" checksum="518333E52BB19EBC" modified="2019-11-13" version="1">MDKFKFWDFGIIDFIDVFLVAILLYYIYKLIKGTVAIKIFIGIIIIYLVWRLTDLLNMFMLNRIFDGFIRVGIIALIVVFQPEIRKFLLMVGSTNLGGRSKLFERITFLKTEHETENDIVAIVSACDKMSSSHTGALIVLERNNSLDFLTSTGDEMNIKVTQPIIESIFFKNSPLHDGAVIIENNVVKATRVILPVSSERNIPQRFGLRHRAAVGITERTDAVALVVSEETGQISYIKAGEFVVFEDISELTTLLNKDLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMG4</accession>
    <name>A0A5C6ZMG4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MBL fold metallo-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_04305</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050313">
        <property type="term" value="F:sulfur dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07724">
        <property type="entry name" value="POD-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044528">
        <property type="entry name" value="POD-like_MBL-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="268"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="373"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="468" mass="51117" checksum="F77A29D5D3C1FF71" modified="2019-11-13" version="1">MNIEQIYTGCLAQGAYYIESQGEVAIIDPMRETQQYIDKAQASGSKIKYIFETHFHADFVSGHIDLANKTGATIVFGPGAKTSYDIHSAADNEEFKLGNIIIKALHTPGHTLESTSYLLIDAQGKDHALFSGDTLFLGDVGRPDLAIKSDLTKEDLAGMLYDSLRNKIMPLANEVIVYPAHGAGSACGKNLSKETVGSIGHEKKTNYALRKDMTKAEFVAEVLDGIAPPPQYFAKNAMLNKSGYDNFETVLKTGNIPLSPEAFETIANNQDALVLDVRNQADFIEAHIPNSIFIGLNGQFAPWVGALITDIKQPILLIAPEGQSEEAVTRLSRVGYDNTLGYLEGGMDAWKASGRDIDKLKSISAETFAKLAKSEDLNILDVRRDGEYKSKHLEDAQHFALDYINSHMNEVSKDKTYHIHCAGGYRSVIAASILKARGYHDLVDVAGGFGAIKHTDLPITEFICPSTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMI8</accession>
    <name>A0A5C6ZMI8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_03910</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014719">
        <property type="entry name" value="Ribosomal_L7/12_C/ClpS-like"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="106"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="125" mass="13988" checksum="72E155DF6517340D" modified="2019-11-13" version="1">MENSILLINGSSLEKQKLLQLIKQGRKPEAIKYIKATARVGLKSCKDIVENLAQNPDYYDSYEEDIALATGINEQKDLGHGQNQKTRESKRKGAHVIASNQDQSKALMMVVVAFTIAVVLYFIYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMX1</accession>
    <name>A0A5C6ZMX1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Prephenate dehydrogenase</fullName>
            <ecNumber evidence="2">1.3.1.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_02120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.12" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008977">
        <property type="term" value="F:prephenate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004665">
        <property type="term" value="F:prephenate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006571">
        <property type="term" value="P:tyrosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003099">
        <property type="entry name" value="Prephen_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02153">
        <property type="entry name" value="PDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51176">
        <property type="entry name" value="PDH_ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prephenate/arogenate dehydrogenase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="283" mass="31665" checksum="82F5BBCB645DCFE0" modified="2019-11-13" version="1">MKQIYIIGVGLIGGSMALDIKSKYENVTVFGIDNNQKHIEEAIALKVIDAEAKLEDLQNADLVVLAIPVDVALLELPKVLHHIADTTLVFDVGSTKSPICQAVEQHPRRRNFLAAHPIAGTEFSGPSAAIPGLFNAKANIICEVEKTAFKLQEKALQLFSDLGMRIRYMNPVAHDKHIAYVSHLSHISAFMLGKTVIDKERNERDIFDMAGSGFESTVRLAKSSPNMWTPIFKQNKDNVIETLEEYISNLQQFKNYMEADDFEGIFNEMKNTNHIKEILKGIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN81</accession>
    <name>A0A5C6ZN81_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cytochrome C biogenesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_03500</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002541">
        <property type="entry name" value="Cyt_c_assembly"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045062">
        <property type="entry name" value="Cyt_c_biogenesis_CcsA/CcmC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007816">
        <property type="entry name" value="ResB-like_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30071">
        <property type="entry name" value="PTHR30071"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01578">
        <property type="entry name" value="Cytochrom_C_asm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05140">
        <property type="entry name" value="ResB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="52"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="433"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="475"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="766"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="797"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="832"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="855"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="888"/>
            <end position="917"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="938"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="977"/>
            <end position="995"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="1002"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="1038"/>
            <end position="1059"/>
        </location>
    </feature>
    <feature type="domain" description="ResB" evidence="8">
        <location>
            <begin position="347"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrom_C_asm" evidence="7">
        <location>
            <begin position="826"/>
            <end position="1030"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD90443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1068" mass="121410" checksum="65954A90B44C6CB7" modified="2019-11-13" version="1">MQKKLANILFSTRLTGTLFIVYAIAMIVGTFLDAGQETSPTPFTRHYIYNAWWFEMIMLLFVINFIGNIFRYRLFRKEKWATLTLHLSFILILVGAGITRYIGFEGWMPIREGATENTILTRDVFLTAYIDGDLEVNGQLQRKVVQERVDFSERLNNDLTFTSDYNGSPVSFEVERFLENAELDVIPGDTGESYLKLVEAGEGTSHNHFIKDGDDELIHNVVFTLNNPKPGAINISTNDDGIFIESPFEGDYMTMATRATGTVVKDSIQPLVLRSRYQMAEMSMVFPNPVTKGEFGIVKKSELLRNVESGVVMKVTANGETKRLNLIGAQYMDGRFEQANVGGLDISMKYGSATKELPFSIKLNDFVAERFPGTENSFSAYSSEVTVLNSDKGDYDYKIFMNNVLDQSGYRFFQASFDPDELGTRLSVNHDRWGTWVTYAGYMLLYFGLMAILFDRKTRFADLKRMLAKIKAKKSKIMTLLVLCFGMTGFAQEHSDDDGHGHAEKIEIQKPSKAQIDSVIRSNIVPKEHADAFAQLVIQDYSGRMMPMDTYASEVLRKLSKSEQYEDFDANQVMLSMQESPLFWYNVPVIYLAKRKADSLRHIIGIDESQKYAALTDFLNEDGSYKLADYLPNAYKAQVPNGYQTQLIEADQRVSLLFNTVEGRSMKIFPVPNDDNNTWISSVEYKEKYESQIKDTLYGKFIENSFNYYISELYKSKQSGDYVTANRLLEGFKRSQAKLGSEVMLSDKKIDAEILYNKYDIFKSLYTYYLLAGAIMFIVLIIQIFKSNSKLVKHTVNGLGIVILLLFIVHTAGLIVRWYISGHAPWSNAYESMIYVAWATMFFGLAFGKDSKLTLAATAFVTAMILMVAHMNWMDPAISTLQPVLDSYWLMIHVAVIVGSYGPFALSMILGVTVLFLMIFTTKKNKEKMLLNIKELTLINEMSLTVGLVMLTIGNFLGGMWANESWGRYWGWDPKETWALISIMIYAFVIHMRLIPGLRGRFGFNLGSIIAFASILFTYFGVNFYLSGLHSYQSGQQIASFNIIAITLLVLAVISILAFRKYDKYYRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNA0</accession>
    <name>A0A5C6ZNA0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GNAT family N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_02260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="23"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="214" mass="24301" checksum="393B79A696A11BE0" modified="2019-11-13" version="1">MDIVIANKSHSVYAQIICDTIAESAKDRGTGIAKRTPEYIISKMENGNAVIALDGENFAGFCYIEAWSHAKFVANSGLIVYPSYRKMGLAKQIKQKIFDHSRKKFPDSKVFSITTGLAVMKMNSDLGYKPVTFSELTDDESFWNGCQTCKNYDVLQRTEQKMCLCTGMLYDPKAKHSIESQEHVYDKKVWTRLKNIKQTMLLRKVKNQTNEGSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNL9</accession>
    <name>A0A5C6ZNL9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Peptidase E</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_05970</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="166" mass="19187" checksum="675C21CB4182982C" modified="2019-11-13" version="1">MTQLKILVLALVLPLLSTMTTHKYYVSVTQMEYVKSKKSLQIITRIDVSDLQLTLRERYDDSITLTEADEKASVNDYIKKYLAAKLDIKVNTKELTIDFVGKEYDNDQVVCYLEIQDVASVKTMEISNTVLFDKFPDQRNVLKIKVNGERFNLVCAVQDQTQYLNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZP36</accession>
    <name>A0A5C6ZP36_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADP-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_01555</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041694">
        <property type="entry name" value="ADH_N_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045010">
        <property type="entry name" value="MDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43205">
        <property type="entry name" value="PTHR43205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16884">
        <property type="entry name" value="ADH_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="13"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="334" mass="36556" checksum="1B67A884FEFA146B" modified="2019-11-13" version="1">MNKQQIFKKRPVGAANASTWSLETNPIPELEEGQVLIKNHYISLDPAMRGWMNEGKSYIAPVEIGAVMRAGSVGEVIKVKNHPTFKEGDFISGHGGVQQYVATDGKGYYKVDPKLAPLPTYIGTLGMPGMTAYFGILEVGKIKEGDIVVVSGAAGAVGSIVGQIAKIKGCKVIGIAGGADKCKYVVDELGFDACIDYKNEDVKQRLKQECPKGLDVYFDNVGGEILDAALGRLRMHARVVICGAISQYNNKENMRGPSNYLSLLVNRATMQGMVVFDWADRYGEAGQQMGKWMAEEKLKTREDVYEGIENFPETYNRLFSGEKLGKLVLKVVED</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPX5</accession>
    <name>A0A5C6ZPX5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Choice-of-anchor D domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_00075</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd06263">
        <property type="entry name" value="MAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1080.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006558">
        <property type="entry name" value="LamG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000998">
        <property type="entry name" value="MAM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028974">
        <property type="entry name" value="TSP_type-3_rpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00629">
        <property type="entry name" value="MAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00560">
        <property type="entry name" value="LamGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00137">
        <property type="entry name" value="MAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50060">
        <property type="entry name" value="MAM_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022688627" evidence="3">
        <location>
            <begin position="28"/>
            <end position="2022"/>
        </location>
    </feature>
    <feature type="domain" description="MAM" evidence="4">
        <location>
            <begin position="410"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="domain" description="MAM" evidence="4">
        <location>
            <begin position="897"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1038"/>
            <end position="1071"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD91033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="2022" mass="220201" checksum="20969D9D343615CE" modified="2019-11-13" version="1">MKNFSLKTLRAGLTLLLLSLAINFSFSQDLKVQHFQEDVPEAGKVITTSTPVSALSKAFAISNNNRKSQAGIPGSGNNMSGSDMSGAMRLTSASTLEYYRDGASVNANTRFSSSIIEYTGPAGGPNEFVVRGRYAIALNGNNNSITQGVGGVTNSRRSIPFITGILNSATNADADSGTAIAYLEDNGILHIRKGSNSNNVTVYITLVEFIGSNWSVLHADSGDTAADTGTLTLRENANGTGSTVNVPNWSNAIIFGQHIGDYITDGTNDAIADNWPIFRPGSNNQHVDWEFHNQHDSNGNNKHFVHVLINNELNVTRYQDDNNAANETAIDISDAGLSDTSQAMIVGSSISSGSGNAYGRGWRNYYLKSITEAAHWAHRRGNDMSHELQIVDFSNMNTLNCNAAVSTFPYNESFESGLGLWSQAVNNDIDWNLKSGGTASNDTGPNNAASGNYYLYTEASDPNFNKNAILESPCFDLTTNDTPQFSFSYHMYGSNMGNLYVELSLNGNSNPIEIWSQNGQDQTENDDPWKTVELDLSAYAGQTVKLRFRGLTGNNYRSDMAIDNISFIDVPPTPDIVVKGNNILINNGANTVNMADGTNYGSHDVGVPSTNTFTIENLGYANLDISSISLSNSIDFSIVAPAYQTTMAHSEITTLSIQFNCLSNSIKSSWVTINSNDALKTPYAFLIKGESKQLFFDSDNDGVFDNVDVDDDNDGIPDSVEELDCQNSNISINTRYKILNETFGTGGRTTINTTYNAVTTYAYEDGSNPANIQGSSLGDGEYTVHNKASNGDGINNTPSQDLSSWAETNWYIGGDHTPEDIDGRMALFNASYDPGVFYTANISGVLPDVPTTYSFWVLNLIPVSGVASDRAPEILVEFRDVNDVVLYSFSTDKIPKSINGNPEASWHNFTSELILNVSEFNVYFINNETGGNGNDLAIDDISFIQSLCDTDGDGIANIFDLDSDNDGIPDSVEAGFATETNGQAYIQNFFDSNANGMHDAMEGLSILDSDGDGTPNYIDLDSDNDTVFDVDESAAGNAANASFHNGDGDVDGDGVGDGSDSDATRETDSNYDGISEYFTDGILDIYDYFSGNNFATAYGNTNQGMGNTYYVKDTDGDGIPDYIDVTSNGSTFDISLTLYADLDANNDGIIDDTSDSDADGIVNLFDTDDSKFGSPRVMDKKLGLYFDGRNDFVEDVPIFGGYNEASMMGWIRVDPDASGTQILFGQNNIMLLVRDDKRIQARVNNTNLFSPPMPKDQWIHVAISYSSTSAQFKLYINGQEVANTSVSTAIGIDTSAFVMGKRPNANNSYFKGYMDEVRLFKKALSADEIQKMVYQEIDNNAGTVRGSVIPRNITDFVDTNNNAALGWNALERYYRMDTYRGDIVDDFSTPGIDSGTGARMHNIKILDNQSAPMPFTTKQSGDLVTALSNASQGVNGIDAVNYDWSIVKVQHDNVTYNDRQKHIGLFVDEMDANSNPIKFSIKEDSEINVSWYLKLDGFMDLEGESQLIQGIDSYLDPTSKGYIERDQQGTSNHFNYNYWGSPVNTNGTTFTVGGVLRDGFTPTSPEPVTWTSSPNGSNSNPLTLSRRWLYTFNDLEGIYPNWQSISENTPVAVGLGFTMKGGGGASEQNYTFTGKPNNGQITAPVSGGNQVLVGNPYPSAIDAYLFIAQNDPALEGSLQEGALYFWEHAPSNNTHILRNYLGGYATLNLTGGVAATTAPSGIAGIGNAAKVPKQYIPVGQGFFVTGDSDGGLIQFNNSQRIFRKESISTSVFLRGTNDENTTFDDGDGDETSNDQFIRLDFITPENAVRHLLLGFMDNANATDNVDYGYDAPINDSYPNDMGFNIDGGQYVIQGVGGFDITKSYPLNIKLTTGGTVQIALSALENFDTDIDVYIHDSVLGTYTQFNNTNFQITLEAGDYPERFSLVFQEDQTLSTIDTEFKDIIANFLQNTDEIYIRTPKSIQVKQVYLINITGQTVGSWNATNLPLSNEIKIPVQNVSEGNYILQVETNLNTYNKKITIKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZQI7</accession>
    <name>A0A5C6ZQI7_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Probable queuosine precursor transporter</fullName>
            <shortName evidence="1">Q precursor transporter</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_02690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the import of queuosine (Q) precursors, required for Q precursor salvage.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990397">
        <property type="term" value="P:queuosine salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02088">
        <property type="entry name" value="Q_prec_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003744">
        <property type="entry name" value="YhhQ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34300">
        <property type="entry name" value="PTHR34300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02592">
        <property type="entry name" value="Vut_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00697">
        <property type="entry name" value="TIGR00697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="165"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="193"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="234" mass="26924" checksum="775105D48B6F29C1" modified="2019-11-13" version="1">MTLKDKLAAQKAYLFLAALFITSLVVSNLIFQKFFYWHPFELEIFGSKLFEISVGVLPYPVTFLITDLISEIYGKKRANQVVIAGIFASIFSLLIILVSDLAPATSWSFVDDATFSLVFGNSAIAVFASMITYLFAQFVDIQIYHFWKRVTKGKKLWLRNNLSTFFSQFVDTFTIILLLSFFGIIPWENFKGLLISGFLFKVIIALLDTPFLYLGVYLFNRRFKLKNNEELEML</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZQJ3</accession>
    <name>A0A5C6ZQJ3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF3347 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_02750</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021782">
        <property type="entry name" value="DUF3347"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11827">
        <property type="entry name" value="DUF3347"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3347" evidence="1">
        <location>
            <begin position="64"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="183" mass="20128" checksum="E866B28558E7C958" modified="2019-11-13" version="1">MNTLKSTLGVVAIAFITLTAVSCKDANKNEAPTPMVNQMHQESMTDDAEMAKPTFTDENTQAMFQHYIHIKTALVNSDAAEAQSGAQKLMEFTEDTALKSTLTQIADSEDLEAQRTAFSDLTEKMTLVVNASLTDGAVYQQFCPMAFNNKGGYWLSTESEIKNPYYGDRMLKCGKVTETLVGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6Z9I8</accession>
    <name>A0A5C6Z9I8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_20670</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000102">
        <property type="protein sequence ID" value="TXD85990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="127"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="35"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD85990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="189" mass="22474" checksum="9FF6F4997426BFA6" modified="2019-11-13" version="1">MENWWTLIGTLLGAIIAGVAVILNSHYSAKSTFKRENKNRLIDEKERDVQELEKLYQDILHSLDKLIRNLGSMAETELEKYYKMEIRLELISTKQITEKLTIVSNSISKMASKLPEMPKEFIPKFEDDSDRKSRLEERTKAKEERKKESKKYVPDIRKDYNILSELMKVDLQKRRILDIDKYVEYREKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6Z9M4</accession>
    <name>A0A5C6Z9M4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000058">
        <property type="protein sequence ID" value="TXD86461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="305"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="404" mass="48156" checksum="4A310F4783CC1D61" modified="2019-11-13" version="1">MKKITILLILFSVNCFSQIAIEKPNNETEIDQPLVAEFNEKIDLHEYKTAEQFLGLVGKELFFLPENSKYDFYSDQYESISYLPKTKFKLGKARYRPNQLVNLKKWDKELIDFLKLKENYFVVDSVNFYNGAFSFREKINGREFNERQEKYQSSISLSGNVEIYTHHKTSNEIIIFNISNKSSSEKLISVPYFNYLTDKYLDKKIILKKRGYKHYTENYEIENYNRKHLDSSQIFQITKITIKEPNTEYHSHYTPVFSLKKLDNTIEELEFYRIKDNLIFWNDFVAGADLREKRETIRKDSLEKEKIADAKLRQEQRELRQIDNEKKRIVRLNKFVKKYGKEYGEIVTNYKVRIGMTKEMCEDSWGKPESINRTTNAYGTSEQWVYDGGSYLYFDNVKLTSIQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAB3</accession>
    <name>A0A5C6ZAB3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000036">
        <property type="protein sequence ID" value="TXD86856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="226" mass="24738" checksum="EE224F415C403B71" modified="2019-11-13" version="1">MKRIFTVLAFTGILISCNSSDKTKTATQESATTETEADSSSNDINPQLKPIDTDEALIATALMAAPKESRAQSKVIGYNMAGEFVTLREGDNEFIILADDPKKVGFSASSYHKDLEPFMARGRALRTEGKTEQEIFAMREAEMKSGQLEITPGSTLHVYYGAKTAYDPETSKVDGAQLRYVVYMPFATSKSTGLPEVPVAPNHPWIMDPGTHKAHIMISPLPEDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAE8</accession>
    <name>A0A5C6ZAE8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19840</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000050">
        <property type="protein sequence ID" value="TXD86583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="180" mass="20894" checksum="B7E55CF15B59B3FA" modified="2019-11-13" version="1">MRKIEHLNKILNIFILFVQIGITLITMIAIYMIFAISDFRGGFDGIIGIAVFQPIMAIVFSLITVFACGLMGLPIRINKKLNEWWRTKFYVSIILTFIGLLFCIMSFLPNLVQQVEYEIDGIMEIVTIPNIFFAISGWFLIAFGILHSFPPYKLQQKITYWLNRKFRSKNNNIVSDRIKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBP2</accession>
    <name>A0A5C6ZBP2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Matrixin family metalloprotease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000062">
        <property type="protein sequence ID" value="TXD86417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031012">
        <property type="term" value="C:extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001818">
        <property type="entry name" value="Pept_M10_metallopeptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021190">
        <property type="entry name" value="Pept_M10A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00413">
        <property type="entry name" value="Peptidase_M10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00138">
        <property type="entry name" value="MATRIXIN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M10" evidence="1">
        <location>
            <begin position="15"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="364" mass="39692" checksum="ED0AC24746F7A773" modified="2019-11-13" version="1">MHFFHHQIVVLLQAIWIFGDDETWSTAIQTTSSQPIDLVTVALHELGHSLGLRHSNVPGAIMNAFYSGSQRFLGTDDILGITQLYPKDRSITGSDIICDSNNYSYSINDLTANDIVNWTVSSNFQINNSTNSSVNVSAINVNNTTGWIEANINGIVVRKDIEIGIVSYHFDNANLTGNSSICGSQYYTYNISGFNHPCVTSVNWSVSPNLTIVSQNATSITVTNNPFNDQYAGLITANLPNSSFVIEKGVWVGVPSNDGLTIQKIGSYDLAVGQWTKLKANYIPLLYPANDPLNVTFEWQIPYSAIRNYPDTAYKDVRPNNSGQLNIGVRAVCDCGNGEWKYRMFNVSGGNGNGGGVLTPVGGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBT2</accession>
    <name>A0A5C6ZBT2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000111">
        <property type="protein sequence ID" value="TXD85917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023052422" evidence="1">
        <location>
            <begin position="22"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD85917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="224" mass="25954" checksum="223A0558D2B03EC6" modified="2019-11-13" version="1">MKKILLLISLLLLLTSCDNEPVDFYPINNNDYSVALDTLANYDNYFIGEFNGELFVSTERFTVGGAVGNTLLDSVSMKYTYAYRISNSEDLKTPFISFHLYESKSKLNPNNYLQYNEYSDFQNYFNYNELDYWEVDNFKNLTTQVSIRHIDYSQLINNSGISYQSTDFGKPPFDENNFQIESIREIENPSVGIELTYSFNCTLLSDSNEVIEIENGRGKCTFLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBX3</accession>
    <name>A0A5C6ZBX3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19115</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000036">
        <property type="protein sequence ID" value="TXD86867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3680.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029024">
        <property type="entry name" value="TerB-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158682">
        <property type="entry name" value="SSF158682"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="179" mass="20987" checksum="39F4FFE6A65E4FEE" modified="2019-11-13" version="1">METINFDQLLLKTAFSCMACDGDIDKREVKLIKRLHKEKKTFGEIDINSEMENLLIAINRDGQQFLKDYFNQLTTSVLSEANELKLIEVAIETIKADNKIEYSEIKFFKVIRSKLKIENKPILEKNPDFEDYLEQDIISDSYLARLQEDFFDTHISNEFELISEIDAETLDSFKQNNEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCA6</accession>
    <name>A0A5C6ZCA6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF2490 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_16485</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019619">
        <property type="entry name" value="DUF2490"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10677">
        <property type="entry name" value="DUF2490"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="219" mass="26074" checksum="049CF15659541B44" modified="2019-11-13" version="1">MKLHLLLFFLIVGLLKMHSQERFTAFFEPEFELTYQVTQHYEYSFGIENRNFVYKSARSDYEVKQVDLSHFSTFRLPSNSSIGLGVQYRFETMFDASEENELRLMQAYQWLMFSNRLENRFRTEQRFYKSTTKYRFRQEFALKFPLEGSVLSHFKTEAESLFELASSQKLELEQRFSIAFGINLAPKTSMTFAAQYRLANYTQVPAHELFFKLGFEVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCH0</accession>
    <name>A0A5C6ZCH0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AAA family ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15565</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010285">
        <property type="entry name" value="DNA_helicase_pif1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029491">
        <property type="entry name" value="Helicase_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010997">
        <property type="entry name" value="HRDC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002121">
        <property type="entry name" value="HRDC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044876">
        <property type="entry name" value="HRDC_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00570">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14493">
        <property type="entry name" value="HTH_40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05970">
        <property type="entry name" value="PIF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00341">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47819">
        <property type="entry name" value="SSF47819"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50967">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HRDC" evidence="1">
        <location>
            <begin position="619"/>
            <end position="699"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="815" mass="92774" checksum="59F402FE9B28F22E" modified="2019-11-13" version="1">MEENEQINLAWDFVNNTNRSIFLTGKAGTGKTTFLHDLKKNSLKQLVVVAPTGVAAINAKGVTIHSFFQVPFGPILPDANLNTSSGFQRKFSKTKINIIKSMDLLIIDEISMVRADLLDGIDQTLRRFRNRNKVFGGVQVLMIGDLQQLSPVIKENEWQLLRNYYKTGFFFSSNAFQQCHAITIELKHIYRQENPKFIEILNEIRTNTLSEAGANELNKRYIKDFKPDPKAGYIFLTTHNHRAEQTNNVELNALTSKQKSYKAKIEGKFSEHAFPNKEELILKVGAQVMFVKNDSSQDKRYFNGKIGKVIYLDKDEVTVKCPDDDEAIITTTELWENINYSVDKETKAITEERLGSFSQMPLRLAWAITIHKSQGLTFEKAIIDAQGAFAHGQTYVALSRCKSLEGLVLKSKIDSSQVINDLQVTSFSKQAEENQPDAKLLEEARTQFQLDCIHEIFDFFDFLFPINRLLDIYYKNRNSIEGAIDTPLIAMKSHLANFLKVSNGFGAQLKVLSSNEPLPELSPKIQERFEKAKAYFKTELEQQLAIPLENFSYSTDNKSLEKDFIQNLELLEQLLATKRSYLNGFTNGFAAQKFLELRAKAVFLAKAPVKKKRSAAVDGTVNLDLFELLRTLRNDIATENDLIHYQIFSQKALYEICEVLPLTKQQLLNINGFGKVRVDKYGDEILEVIHAYCDENDIQVDDSEMKEPKKTAKPVKKGATHETSLKLYQDGKSIFEIAKERALAQTTVFGHLVKFVSSGEVQLHDLITKEHYKELIAILPKLTFESLTDLKQQVDEKYSFNDLRVVLMALDSKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCH8</accession>
    <name>A0A5C6ZCH8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0173 metal-dependent hydrolase ESY86_17220</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_17220</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0173 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000026">
        <property type="protein sequence ID" value="TXD87303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00457">
        <property type="entry name" value="UPF0173"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022877">
        <property type="entry name" value="UPF0173"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="2">
        <location>
            <begin position="7"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="225" mass="25064" checksum="102F50C6E861779A" modified="2019-11-13" version="1">MKITFYGHASLGIKVDDTYILVDPFISGNPKASAIDIESLKADYILVTHAHQDHILDVESIAKRTGAVVISNFEIANHFDALGIETHPMNHGGQWDFEFGNVKYVPAIHTSSFPDGKYGGQPGGFVIEGERKNIYIAGDTSLTMDMKLIPMFTKLDLAILPIGDNFTMGIDEAIIASDFVQCDKILGYHFDTFGYIEIDHEEAKRKFFDKDKDLMILEIGESIEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCJ4</accession>
    <name>A0A5C6ZCJ4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">KilA-N domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19105</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000036">
        <property type="protein sequence ID" value="TXD86865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017880">
        <property type="entry name" value="KilA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018004">
        <property type="entry name" value="KilA_N/APSES_HTH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04383">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01252">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51301">
        <property type="entry name" value="KILA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KilA-N" evidence="1">
        <location>
            <begin position="5"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="276" mass="31408" checksum="CADE4B4FCF28EA78" modified="2019-11-13" version="1">MAKTKQIEVQGSVINLSIAKDSDYICITDMANAKDGSGRAADIIKNWIRTRTTLEFLGTWEQLYNPDFKVVEFDHFKMEAGLPSFVLSPSKWVETTNAKGIYTKKGKYGGTYAHKDIAFEFGSAISPVFKLFLIKEFQRLKDDENERLNLEWNLQRTLSKINYKIHTDAIKENIVPNLISKSQINFVYANEADLLNVALFGITAKQWKVENPSSKGNMRDEASIEQLVVLSNMESINALLIEQGLTQKDRLVQLNKVAIMQMKSLLENESFKKLDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCK6</accession>
    <name>A0A5C6ZCK6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CoA pyrophosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17385</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000026">
        <property type="protein sequence ID" value="TXD87333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010945">
        <property type="term" value="F:CoA pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03426">
        <property type="entry name" value="CoAse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045121">
        <property type="entry name" value="CoAse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12992">
        <property type="entry name" value="PTHR12992"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="46"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="213" mass="23940" checksum="CCF516ABC3A9E551" modified="2019-11-13" version="1">MQFEDFKSKIKTISAEALPGEASQFKMSPPFRADLIAANKLKMKTARKAGVMALFYPNLEGETYLILILRKTYRGVHSAQVGFPGGKYELEDPDLKYTALRETYEEVGVPIESMELIRALTPMYIPPSHFTVSPFLGITSKTPVFIKQDEEVEDLIEVSLTDFLDNKNTTTVEVMTSLEKELTVPAFILNGYIVWGATAMMLSELKDLLKMVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCL6</accession>
    <name>A0A5C6ZCL6_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Putative fluoride ion transporter CrcB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9 10" type="primary">crcB</name>
        <name evidence="10" type="ORF">ESY86_18995</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Important for reducing fluoride concentration in the cell, thus reducing its toxicity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the CrcB (TC 9.B.71) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000035">
        <property type="protein sequence ID" value="TXD86899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903425">
        <property type="term" value="F:fluoride transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00454">
        <property type="entry name" value="CrcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003691">
        <property type="entry name" value="CrcB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28259">
        <property type="entry name" value="PTHR28259"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02537">
        <property type="entry name" value="CRCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00494">
        <property type="entry name" value="crcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="96"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD86899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="121" mass="12852" checksum="CA3AD19D93207C0C" modified="2019-11-13" version="1">MKQLLLVFVGGGIGSVLRFLIGKFLNNPNTGIPYGTFAANILGSLLIGIILGMAAKNDALSSNQTLLLATGFCGGFTTFSTFAYENHVFLKSGDFMSFAIYTIASFVLGFLAVFLGMYLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCN6</accession>
    <name>A0A5C6ZCN6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Polyphosphate kinase 2 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_17555</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000027">
        <property type="protein sequence ID" value="TXD87240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008976">
        <property type="term" value="F:polyphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006797">
        <property type="term" value="P:polyphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016898">
        <property type="entry name" value="Polyphosphate_phosphotransfera"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022300">
        <property type="entry name" value="PPK2-rel_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022488">
        <property type="entry name" value="PPK2-related"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03976">
        <property type="entry name" value="PPK2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028756">
        <property type="entry name" value="PPK2_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03709">
        <property type="entry name" value="PPK2_rel_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PPK2" evidence="4">
        <location>
            <begin position="29"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="23"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD87240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="292" mass="34660" checksum="37273A9D58F524DA" modified="2019-11-13" version="1">MKKIDIKDFKITEQFQLKNVSTSFDLDADKKKIEKELEEVREDLGDFQNKIYAHGKYAVLVCIQGMDTAGKDSLIREVFKDFNSRGVVVHSFKVPTDLEKKHDYLWRHYIALPARGKFGVFNRTHYENVLVTRVHPEFILGENLPDVNTLEDINEAFWEKRFEEINNFEKHIAENGTIIFKFFLHLSKDEQKNRLLRRLDKPEKNWKFSPSDLEERKLWDTYQACYEDAINKTSKFHAPWYIVPADDKPTARYIVARTLYDTLITYTDIKEPRLDPEIEANLDDYREQLNND</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCP8</accession>
    <name>A0A5C6ZCP8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF1343 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_16165</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033922">
        <property type="term" value="F:peptidoglycan beta-N-acetylmuramidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008302">
        <property type="entry name" value="NamZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42915">
        <property type="entry name" value="PTHR42915"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07075">
        <property type="entry name" value="DUF1343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016719">
        <property type="entry name" value="UCP016719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="419" mass="46727" checksum="19A960D5C3EDDEEF" modified="2019-11-13" version="1">MHLSKSKNRVFPVIIVLLLVLISCGNGSKSAAQNTKAENESSKTETTKLESNIVVAANRTEAYLPMLKGKRVGIVANQTSVIFAENKATGTHLVDSLKQLQVNIKCVFAPEHGFRGEADAGQLITDGVDPKTQLPVISLYGNNKKPTPKQLEGIELMIFDIQDVGARFYTYISTLHYIMEACAEAKIPLLILDRPNPNGYYVDGPILEPQHKSFVGMHPIPVVHGMTIAEYAQMINGEKWLKDGLQCELSIIPMKNYNHDKRYSLPIKPSPNLPNDQAINLYPSLCFFEGSNVSVGRGTTKQFQIFGSPYLDKSKYEFSFFPSPKPGASNPKHDGKLCYGRDLSTHERLEQLDLSFLITAYKNSIDKSLFFTDFFTKLAGTKTLEAQIKAGKTEQEIKASWEEGLAAFEKTRETYLIYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCR9</accession>
    <name>A0A5C6ZCR9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_15420</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="231" mass="27373" checksum="C4393EA6166DF5EE" modified="2019-11-13" version="1">MIENLIKWKEGVYEFNTRLIKSLEEKSNYKDLYFGFEIFDGKPITNPEILFIGINPGRGNGDSGKKIIETDQISYLDIYNDDYRDDYPNTYHLAEKTIKFFKLINWSDEKIKSIFKEKVVKSNFFHLATENINDLKKVIDDIQYSNEYFKKSAYFSIQLINILKPKVVILEGKTVFNNIVEQCYEQKVWTSNDFGYLYDKVNNTHIIGYKRSSFTNENREFFTNKLQDILS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCW4</accession>
    <name>A0A5C6ZCW4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">SDR family oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_17345</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000026">
        <property type="protein sequence ID" value="TXD87326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="227" mass="24787" checksum="F868161D232E9AB5" modified="2019-11-13" version="1">MKTYIVVGGSKGIGNAIVTTLLENHKVINISRSKPETEHEHLKHYSCDVLKEDLPDIEAADGLVYCPGSINLKPIGRFDLDEFREDFEINVIGAVKTIQKYLNIIKKGKDPSIVLFSTVAAKLGMPFHASVAAAKSGVEGLVKSLGAEMATTLRINAIAPTVTDTQLASKLLRNDKMIENITDRHPMKKFLKPQDVAGMAEFLLSEKASSISGQVFEMDCGIVTFKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCX1</accession>
    <name>A0A5C6ZCX1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_20025</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000054">
        <property type="protein sequence ID" value="TXD86520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="203" mass="24318" checksum="287E4BC3A8E22781" modified="2019-11-13" version="1">MNQEIKILRSDLVAKCDQYLNGEIKEKDFEDYAWNLITEEHFDWNDDVISNIIYQWDSPEINFPITKTNIRLWKHQLETDENLLADYNLWNVHIDQQKEICEKYQSKWKPINKKLMIGIGSDLTADPIHGLRHPKEKGTTGWNIWTGEYSESDDFFKPICAEHLLQIRPDLIKYFGLDVGYRFLIDKKEYEDVWFDEKLKITE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCX3</accession>
    <name>A0A5C6ZCX3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transketolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000033">
        <property type="protein sequence ID" value="TXD86956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02012">
        <property type="entry name" value="TPP_TK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005474">
        <property type="entry name" value="Transketolase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00456">
        <property type="entry name" value="Transketolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TRANSKETOLASE_1" evidence="1">
        <location>
            <begin position="15"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="281" mass="30917" checksum="53263DCD416734D7" modified="2019-11-13" version="1">MSNTQQLKDLTTQVRRDILRMVHKVNSGHPGGSLGCAEFFVALYKEIMDRKDSFEMDGIGEDLFFLSNGHISPVFYSVLARSGYFPVEELNTFRLIDSRLQGHPTTHEGLPGIRVASGSLGQGFSVALGAAQTKKLNKDQHLIYSLHGDGELQEGQNWEAIMYAAGNNVDNIISTIDYNGQQIDGPTDVVLPMGNLKEKFEAFGWTVVDILQGNNIEEVLKGMAVAKSKTGQGKPVCVLLHTVMGNGVDFMMHTHAWHGKAPNDEQLEIALKQNPETLGDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD08</accession>
    <name>A0A5C6ZD08_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18605</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000032">
        <property type="protein sequence ID" value="TXD87002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045391">
        <property type="entry name" value="DUF6520"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20130">
        <property type="entry name" value="DUF6520"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022901290" evidence="1">
        <location>
            <begin position="25"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="89" mass="9308" checksum="C06A3091768CF792" modified="2019-11-13" version="1">MKTRKIQFLMPVLAIVFAMTSAFSTSGNKGEAALSVIAGYIDSPSPCMVPVTCSTIIGPICTNGLNGPQAFGKSNPNATICPLTVYRPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD14</accession>
    <name>A0A5C6ZD14_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Adenylate/guanylate cyclase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_18750</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000033">
        <property type="protein sequence ID" value="TXD86972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="2">
        <location>
            <begin position="177"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="357" mass="41962" checksum="5F3A858ED0095091" modified="2019-11-13" version="1">MYAIKQFFKLLFNSILFWSFAFCSFIIIRYYGRNQEQVHTAQLNDVVTASEYLIFGVVLGVMVAIIYTIIEFLFDKFFSKILHLGFILLFKSFIYFIFLIFSLTFIAHLAEAYIKVDFPNERGWWVYNKVFWVVTIYFIFCSLLFSFMRLTNDKFGKGVIFKMIIGRYRNPREVERVLMFIDLKSSTAIAEKLGHLKYSRFIQDCFYYLNRIVNKYDAEIYQYVGDEAVLSWSLKKGVNNLNCVNLFFDYENKLNRHSKYYMKKYGVVPEFKAGIHAGKIIIAEVGTIKKELAYHGDVINTTSRIQEMCNEYSESLLVSEEFLAELNLANKYKAIPLGDELLDGKTEAHRLYAIQKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDE2</accession>
    <name>A0A5C6ZDE2_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HAMP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17955</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000028">
        <property type="protein sequence ID" value="TXD87199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HAMP" evidence="1">
        <location>
            <begin position="3"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="206" mass="23825" checksum="BA714DCD506139FE" modified="2019-11-13" version="1">MEDDILYRMQIINEMLLEMASGNFYYRIERSENDDNIEALIATLNMLAEEIQETIVHQGYANTEHTTLDIVQMSFILNSKGFIEMVNQKTCNILSALYDDIIGKDFENFLAKASIAKWKATWNLIKEKEIFDTSLDLNFKSKGKLIIPKIAYITTFIDRLSKENKTLVTVVHHSNFKKQLDADLKERVIGSLYIRLVSISCNACYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDJ9</accession>
    <name>A0A5C6ZDJ9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Nuclear transport factor 2 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_17570</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000027">
        <property type="protein sequence ID" value="TXD87243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030638">
        <property type="term" value="P:polyketide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009959">
        <property type="entry name" value="Cyclase_SnoaL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38436">
        <property type="entry name" value="PTHR38436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07366">
        <property type="entry name" value="SnoaL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="307" mass="34681" checksum="959EDCB6A1A2FCFA" modified="2019-11-13" version="1">MKKLILLGLAIVLFTACDKQDKRYTQQSPEIETVKKFLDDYNNKVYDTSIYADSSKSFFNASKDEFMSPSETVAMHKQNDELYSKRGFTNEDPEYEMVVTDDGETWVNCWLDWKGTLAANNKEFEMPVHLTYRFVDGKIVREVAMFDPSKIVLEVQAIEAEKNMSVDEKTILAAANTAIKAWNTNDKELMSSFMTPDISRLTDGVKTQSGTKEYGEMMDSFHSAFTGFTVTMNNIDIKNNKAYISWTISGKNTSTYMGNPATNKELSLPGFSVWTFNGDGKAVEEHAYTDNLAMLQQLGYSDPAPPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDP3</accession>
    <name>A0A5C6ZDP3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribosome-associated translation inhibitor RaiA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">raiA</name>
        <name evidence="2" type="ORF">ESY86_16255</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044238">
        <property type="term" value="P:primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00552">
        <property type="entry name" value="RaiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036567">
        <property type="entry name" value="RHF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003489">
        <property type="entry name" value="RHF/RaiA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02482">
        <property type="entry name" value="Ribosomal_S30AE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69754">
        <property type="entry name" value="SSF69754"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00741">
        <property type="entry name" value="yfiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0810">Translation regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="100" mass="11726" checksum="BEC6BC673F59BE58" modified="2019-11-13" version="1">MKVNTQSVNFNADQKLIDFIQRRMDKLDLFYDKVIHSDVYLKVQKTSDKENKIFEARVNVPGDSFVVKKQCKTFEEGTDMAVSCLERQLKKRKAKLRAHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDS0</accession>
    <name>A0A5C6ZDS0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Asparaginase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_19280</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the asparaginase 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000038">
        <property type="protein sequence ID" value="TXD86797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004067">
        <property type="term" value="F:asparaginase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08963">
        <property type="entry name" value="L-asparaginase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006033">
        <property type="entry name" value="AsnA_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036152">
        <property type="entry name" value="Asp/glu_Ase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006034">
        <property type="entry name" value="Asparaginase/glutaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020827">
        <property type="entry name" value="Asparaginase/glutaminase_AS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040919">
        <property type="entry name" value="Asparaginase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027473">
        <property type="entry name" value="L-asparaginase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041725">
        <property type="entry name" value="L-asparaginase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027474">
        <property type="entry name" value="L-asparaginase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037152">
        <property type="entry name" value="L-asparaginase_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00710">
        <property type="entry name" value="Asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17763">
        <property type="entry name" value="Asparaginase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001220">
        <property type="entry name" value="L-ASNase_gatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00139">
        <property type="entry name" value="ASNGLNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00870">
        <property type="entry name" value="Asparaginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53774">
        <property type="entry name" value="SSF53774"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00519">
        <property type="entry name" value="asnASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00144">
        <property type="entry name" value="ASN_GLN_ASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51732">
        <property type="entry name" value="ASN_GLN_ASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Asparaginase" evidence="4">
        <location>
            <begin position="7"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="Asparaginase_C" evidence="5">
        <location>
            <begin position="219"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="16"/>
        </location>
    </feature>
    <feature type="active site" description="O-isoaspartyl threonine intermediate" evidence="2">
        <location>
            <position position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR001220-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD86797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="343" mass="38298" checksum="7F4B838402B08ADA" modified="2019-11-13" version="1">MAVRQPNILLIYTGGTIGMIKDSKTAALKSFDFKNLLKRIPELRLLACEIETVSFEQPIDSSNMRPEYWVMIAELIESNYDDFDGFVVLHGSDTMSYSASALSFMFENLTKPIIFTGSQLPIGDLRTDAKENLITSIQMASLQTYGRPVIREVGLYFEYKLFRGNRTTKINAEHFEAFESLNYTHLAESGVHLKVNNDALFVPNTRKKMVVHKKFETSILLVKMFPGISENILKGMFACEAIKGIVLETYGAGNTTTEDWFIDLLKATIKKGIPIINVTQCSGGSVAMGQYETSTQLRAIGLTSGKDITTEAALTKLMFMLGEEVSMNSFKTIFETSLRGEMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDU3</accession>
    <name>A0A5C6ZDU3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4870 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000021">
        <property type="protein sequence ID" value="TXD87654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019109">
        <property type="entry name" value="DUF4870"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09685">
        <property type="entry name" value="DUF4870"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="111" mass="12455" checksum="3146C10275843A86" modified="2019-11-13" version="1">MREDKQLIVLTHLSQLLSFITGFGGLIVPLIIWVTQKETVFQMDEQGKRIINFQISMLIYCIVCIPFIFILIGIPALILLGLLSLILPIINAIKASNGELPTYPLTISFLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDV5</accession>
    <name>A0A5C6ZDV5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_18525</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000032">
        <property type="protein sequence ID" value="TXD86990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="229" mass="27574" checksum="1EB2048B2E997BBB" modified="2019-11-13" version="1">MNIRLNKIIIENCKEFDLWTEILNQQRASIFTEEIQSEEEFTNVTYETSAVLGKIADLAIRYGNFKDDFDTSKMHLNLYGPSLIIKSIKTNGTYYLATDLEGIYLRTSFLHAENLKNMRDDFWSELFELKKFSGFEYEENSFFSIDVQRKYPELFQNYKDTMFLMFRKYFLSYTEKHNDIDIGFFKVQWKPEEDFGKMIEEICLAFKSMYKLDYKLWKITELRNKKSNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDZ3</accession>
    <name>A0A5C6ZDZ3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">tRNA-(Ms[2]io[6]A)-hydroxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_15000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045301">
        <property type="term" value="F:tRNA-(2-methylthio-N-6-(cis-hydroxy)isopentenyl adenosine)-hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07910">
        <property type="entry name" value="MiaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010386">
        <property type="entry name" value="tRNA-Hydrxlase_MiaE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42637">
        <property type="entry name" value="PTHR42637"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06175">
        <property type="entry name" value="MiaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF020736">
        <property type="entry name" value="MiaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="193" mass="22597" checksum="B8D2C9F2ED92B887" modified="2019-11-13" version="1">MLHLQLETDPRWVDIVESNIEEILTDHAWCEQKAATNAITIITHNSQYPDLVTDLLELAKEELEHFQMVHEIIKARGYTLGRERKDSYVNELYKFMNKGGNHLQSMVDRLLFSAMIEARSCERFKLLSQNIKDPELSKFYYDLMVSEAGHYTLFISYARKYGKEIDVDKRWKELVAFEGELIKSYGKSETIHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE22</accession>
    <name>A0A5C6ZE22_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NUDIX domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_15125</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD88005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="3">
        <location>
            <begin position="67"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="193" mass="22290" checksum="E6528019996F0985" modified="2019-11-13" version="1">MHKVFVNDKPIVLTTTVEEEDGFKNYLLSRVSIGKVIKVLNKTSLKEVRLIGKKEEKLLKKFLKKLPNVIAGGGKVYNTEGKILFIYRNDKWDLPKGKAERKETIEETALREVEEETGVTGLEIVSRLESTYHIFKRNGKHKIKITHWFEMKTNFEGELQPELNEGITQVKWLTAEESRDALENSYANIRSLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE25</accession>
    <name>A0A5C6ZE25_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Cell division protein FtsX</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">ESY86_13890</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Required for cell division and gliding motility.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the ABC-4 integral membrane protein family. FtsX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004513">
        <property type="entry name" value="ABC_transpt_FtsX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040690">
        <property type="entry name" value="FtsX_ECD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47755">
        <property type="entry name" value="PTHR47755"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18075">
        <property type="entry name" value="FtsX_ECD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003097">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="8" id="KW-0132">Cell division</keyword>
    <keyword evidence="8" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="4 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="17"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="163"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="221"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="252"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX_ECD" evidence="10">
        <location>
            <begin position="52"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR003097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF18075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD88186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="292" mass="32978" checksum="42B9DD3CA19F1B25" modified="2019-11-13" version="1">MASTFDQYQKRKLISSYVSVVISIALVLFLLGCLGLLVLNAKKVADHFKEQVVVTIYLNESAKEVEINQLEKSLAMAEYTKKTEYVSKEEAAELMKAETGEDFMDFVGYNPLQNSIDVYLKADYVTNETLDGITEELANKKFIEEIRYDNDLVELMNDNVKKITFWVLILSGLFTLIAVLLINSSIRLQVYSKRFIIKTMQMVGATKSFIRRPFIGKSVQLGVVGAIVALLGMGVVLYYMDKTFPELQLLQSPVLIASLFIGILLLGILITGISTFIATQRYLNLKTDHLYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE43</accession>
    <name>A0A5C6ZE43_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000025">
        <property type="protein sequence ID" value="TXD87379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022888662" evidence="1">
        <location>
            <begin position="23"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="583" mass="65638" checksum="6E2BCC36CCDBECE3" modified="2019-11-13" version="1">MTNLKAILVCVLLLFSLAKVQAQIIQVTEIDRGSSRSISLAEAQIIDINASLEINLSKTELLKMIAEQYPQYTQQTALESKINAISDALLNQEAILNSLILGVENVESQQQFFDLMELFLMTIGENEMLSQRYEILSEAYFNLENHETLNMEAYIFSRFNADALELKEQLKLMEATKYNVSLVAFKKDKLGGDRVHVQNFDTYTERDYVTIERWVTSLSDSQEEQIAGLAEKAKTNEAKTLRIFESLKTKLITYLPNLDCVQAQKENLMTLLNNPETYGDLTADITLQANELFSRLNALSSMVTAFKSDIGSWTITTPFELKTNLENFSKNSKHLTEDFELLESLSKAIERLRPKFDQLFQGFEPCVLEFEAYFKVVQETLTLLKLQQSNYIVNKTIGDEVHRFSIDNLPSKGFINLKGTGSRTNGDELVLEVVLRVPSTLEGAPEQQFLLEQRSFYMQLIGARSEVAVGMILANPIGSTNPAIDPARSFFYAPSASILLKFGSKSSYFYNEFVDLGVGLNFAASDFDTDGTPEFGTGLVVTGFKDIISFGINYNVTLDEPYWFFGINLPFNLPGLPINSVKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZED3</accession>
    <name>A0A5C6ZED3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">NAD(P)/FAD-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_18260</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="2">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000030">
        <property type="protein sequence ID" value="TXD87077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="5">
        <location>
            <begin position="6"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_dim" evidence="4">
        <location>
            <begin position="340"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="173"/>
            <end position="180"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="3">
        <location>
            <begin position="43"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD87077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="453" mass="49416" checksum="1FD4FF5E3AE72CCC" modified="2019-11-13" version="1">MKTKHYDVFVIGSGIAGQTAAKACAEKGLSVAIADVREFGGTCAIRGCDPKKVLIQFADLMQHAKQLEASGIKKLPKIKWKTVQKFKSSFTKAVPKNTEKNLSGLGIDLYHQSPKFISETEIMVEGKKVSAETFVIATGYVPRELQFDGANLLGSSDDILNLKKIPKSATFIGSGYVGMEFCYMLSAMGCKVTVLEVSDSALSQFDPFLVNKVVDRLKKGGVEFVFNAETISVEKGKKNLKIKYKHNGKVQKIKSRVAFNTSGRVPATALLDLEKANIKADGSGVLVNDFLQSVSHDNAYACGDVSSKSLPLTPLSGLQGYIVGYNIINGNKKKFEDPLVPSVVFTHPNLASVGYSEEEAKARYKNVKVYHGDATDWYNAKKENAEAYAYKIVTNERTGEIVGAHLLSSRANETINVLATAINNGMTVDAFKKMIFTYPSYSSDLKSMMKDAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEF1</accession>
    <name>A0A5C6ZEF1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Zinc-dependent alcohol dehydrogenase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12885</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="14"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="334" mass="37086" checksum="2A03254D185CD74B" modified="2019-11-13" version="1">MKINCSVIRFHKTGELDVLALENVTMEDPENDEVLFKVDAFALNRADVLHYQGFHTTVPDFPSRIGSEATGEVVKVGNKVTDFKVGDRVTSIPFNTAKYGVQGEYAVVPQDYLTKAPKNLTVEEACSIWMQYSTAYFALFHIGSVKKGDYVFIPAISSSAGYGCFELARDAGAIAICSTRTSVKKEELKQLGIDHLIVTKEEPVEKRLMEITNGKGVSFVYDPVAGAFCDEYLEALSTGAVVIIYGLLDPNPTLFPLVPLIRKKATMDAYSQFNHVEDIVKLNECKAYILDRVGKGAIKPVVSKVFDFKDYKKAYEYMLSNQQVGKIVVRVNTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEK8</accession>
    <name>A0A5C6ZEK8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">SRPBCC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_15115</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="131" mass="14703" checksum="91F66C536C301CB5" modified="2019-11-13" version="1">MKLESKKTIIPKSAEETYHFLSDVKNFEKLMPENISKFEVLGEDKFLFALKGMPEIVLKKKEAIPYNKIILGAAGGKLDFSLTAIILEITGDSSEVQLKFEGEFNAMMGMMIKSPINKFLETLATNLPKEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEW2</accession>
    <name>A0A5C6ZEW2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">LemA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_12325</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LemA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023353">
        <property type="entry name" value="LemA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007156">
        <property type="entry name" value="MamQ_LemA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34478">
        <property type="entry name" value="PTHR34478"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04011">
        <property type="entry name" value="LemA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140478">
        <property type="entry name" value="SSF140478"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD88523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="200" mass="22334" checksum="46CC3578DFD94B30" modified="2019-11-13" version="1">MKKWLIPVIIIALIGFALYSWGKGFNNTAVQLNENVGQAWGNVQTSYQRRNDLIGNLVNTVKGAADFERGTLTDVIEARAKATQTTIDPSNITPEQLKQFNEAQGGLSSALSRLLVTVERYPELKANQNFLKLQDELASTENTIQTARTRYNEAINPYNNHVKKFPNSILAGLFNFEGKAYFDAEAGAERPVEVEFDFSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF27</accession>
    <name>A0A5C6ZF27_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">6-phosphogluconate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000025">
        <property type="protein sequence ID" value="TXD87371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="121" mass="13940" checksum="8B4D469656999BEC" modified="2019-11-13" version="1">MKKVISIVVISTIAILAIYYLVIYFVPYSEGYRSGELIKFSTKGVIIKTWEGEISQGISGAQIFSFSVLDKDEEVIKNLKEFQGDYVKLSYTQRFGTFFWLGDTKYFVTKVEQEDSPHVRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF67</accession>
    <name>A0A5C6ZF67_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DinB family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11785</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024775">
        <property type="entry name" value="DinB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12867">
        <property type="entry name" value="DinB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DinB_2" evidence="1">
        <location>
            <begin position="39"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="172" mass="19834" checksum="3FDFD099BC7F06A4" modified="2019-11-13" version="1">MMTKDDLNSTEYNTFFQAYIQKSGSLDLIDGLVNSGKITTQFLEAIPRDLLEYRYEAGKWTIKEIIQHLIDTERIFANRALRVARKDQTALPGYDHESFAVHSLANRRTFEDLIMEYQALRQTTILLFKSFDPGMLMEIGTVSDKNLSARAVGFIIVGHETHHCDIIKQRYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF86</accession>
    <name>A0A5C6ZF86_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">30S ribosomal protein S1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_17160</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000025">
        <property type="protein sequence ID" value="TXD87398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035104">
        <property type="entry name" value="Ribosomal_protein_S1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10724:SF7">
        <property type="entry name" value="PTHR10724:SF7"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00681">
        <property type="entry name" value="RIBOSOMALS1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="S1 motif" evidence="2">
        <location>
            <begin position="81"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="2">
        <location>
            <begin position="162"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="2">
        <location>
            <begin position="249"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="2">
        <location>
            <begin position="334"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="2">
        <location>
            <begin position="421"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="2">
        <location>
            <begin position="508"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="620" mass="69741" checksum="C75CBAF695071E0F" modified="2019-11-13" version="1">MSEKETNQAEVETSTEATTVETTETQTEKTHKQSEAQANPEKFLEDFNWHNYEEGIDPVDDKQLEEFEKLVSENFVDTLDDEVVEGTVIHLSDRDAIIDINAKSEGVISLNEFRYNPDLKVGDKVEVLIDVREDSTGQLILSHRKARVIKAWERVNNAHDNGEIVNGFVKCRTKGGMIVDVFGIEAFLPGSQIDVKPIRDYDQYVNKTMEFKVVKINHEFKNIVVSHKALIEADIEEQKKEIISQLEKGQVLEGTVKNITSYGVFIDLGGVDGLVHITDLSWSRINHPNEIVDLDQKLNVVILDFDEDKSRIQLGLKQLSKHPWEALGDTVKIGDRVKGKVVVIADYGAFVEVEEGVEGLVHVSEMSWSTHLRSANDFVKVGDEIEAEILTLDREDRKMSLGIKQLSQDPWTDITSKYPVGSKHTGIVRNFTNFGVFVELEEGIDGLIYISDLSWTKKIKHPSEFCNVGDNLDVVVLELDVSGRKLSLGHKQTEENPWDKYEAEFALGTLHTAEIGEIVDKGATIDFNEDIVAFVPQRHLEKEDGNKLKKGESAEFKIIEFNKEFKRVVASHTAIFKEEEIANVKAAVKKQETQAAEAKPTLGDANDALQALKDKMDGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFG3</accession>
    <name>A0A5C6ZFG3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_12645</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="69" mass="8097" checksum="4156AB94C28359C7" modified="2019-11-13" version="1">MDKASRILTEISTVARDIEENYPELQKYLDETQDTLPEGANTNAKMDEKSLETYLNTLKEMIKKYEEEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFM0</accession>
    <name>A0A5C6ZFM0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CPBP family intramembrane metalloprotease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_14190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="165"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="188"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="212"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="231" mass="26121" checksum="49B892EC6ECDCE25" modified="2019-11-13" version="1">MEQEKKTSVWKTLSILIVFPILYMLFGETYIAKELFANKNLDYYIPFWGGIIILHWTSVFVIMRFLKSEGKTLADIGYKLSRKGTLLLVGGYFLIAFLLVVGIEVMLSNVELDNSRFGNLSGLIPKTTPHRLFFLFLVLSTGLCEEIVYRGFAINQLEKIGLNKWLALIIAALIFIGIHGINAYSGSFIFYFGGGIMFGLVFLFSKRLLPSIILHLAINLSAMMAILELMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFN6</accession>
    <name>A0A5C6ZFN6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF3575 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_14200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021958">
        <property type="entry name" value="DUF3575"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12099">
        <property type="entry name" value="DUF3575"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023130058" evidence="1">
        <location>
            <begin position="19"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="167" mass="18589" checksum="4B74B6954479AB14" modified="2019-11-13" version="1">MKKLITSLTLLICVFVNAQEIENNFSEIKLNTLSASLGTIEVEFERTINSKSSVGLSLFTTFDDSGQAFSYDYGSGITGFYRYYLGKKYASGIFFEGFGMLHNTRYPSNNSQRDINTNLLAGLGIGYKWISKKGIIIQANFSPGINIFNDEFETISGRAGISIGYRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGD1</accession>
    <name>A0A5C6ZGD1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_10270</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="400" mass="46199" checksum="5B44E469F954E468" modified="2019-11-13" version="1">MIPKNRKAYNAHFSEEKYKAFLADINAQFDYTVQFKIAETPAFIPKTLQDKLVAACDDIMKVINQPNFKELTDGAFFDKNTIVPNEDAQSKFIQLDFGICKDEHGELTPKLIELQGFPSLYFFQELLGRMYRKHFGEVIPESYSQHLNGMTPEKYIALLRNEIVGQTDPKQVILLEIEPEKQATAIDFYATEAKLGIKVLCITNLKKRGKTLYYLDESGNEVNVRKIYNRIIFDELHQRKDLKTEFSFKDEVDVEWIGHPNWFYRISKYTMPLLKGDYVPKSYYLDKLENIPSDLENYVLKPLYSFAGAGVQIHVTRDMIDAITNKSNFLLQEKVAYAPVIETMDEPAKCEIRMMLMHNSKTNQTEIVSNLMRLSKGEMVGVKYNKDKTWVGGSTGFFEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGF5</accession>
    <name>A0A5C6ZGF5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039060">
        <property type="entry name" value="Antitox_HigA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40455">
        <property type="entry name" value="PTHR40455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="61"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="123" mass="14249" checksum="49BC702E7EB46CD0" modified="2019-11-13" version="1">MELRPNKSEIDYRNALGRLEVIFDAEIDTKEGDEAYVLSLSIENYENEHYLIEAPDPIEAIKIRMEAFNMRQKDLVGIIGGKSRVSEILNIKKRLTVEMIRELEKTLQLSASVLVHNYQLNEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGQ3</accession>
    <name>A0A5C6ZGQ3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Mobilization protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_09665</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043766">
        <property type="entry name" value="DUF5712"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18976">
        <property type="entry name" value="DUF5712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="343" mass="39051" checksum="849FCCF81FCF67C7" modified="2019-11-13" version="1">MYITITPQKLGGNYSQGSADFVGYLEKENQGLEEGDMEHFFNQYGDEISAEEVIKDIDGNAAKLKKSEPKFYSITVSPSKYELNRLQNSSEDLKKYTRELMKDYVESFNREINGLPISIDDIKYYAKIEHQRSFKGTDIQIKENQSYATKILQLKTEIRNVQDGRAEGNINKMQKEVSKLEKQAPHQQDGKRIVQGMPKAGNQSHIHIIVSRKDASNTFSLSPGSKHKASEVEMHGKNVKRGFDRDKFFTSAEKTFDKTFGYQRNFAETYKARKDFIKNPKIYFAALMKLPTNEKALAFKIMGKTGIPMMPSIPVTQAQLAMKVFNRLRRGVEVAINSSSIGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGY3</accession>
    <name>A0A5C6ZGY3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">OmpA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_08415</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OmpA-like" evidence="3">
        <location>
            <begin position="186"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="24"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="319" mass="35174" checksum="F6EE21EC4BF39727" modified="2019-11-13" version="1">MIKKLSFIALTLLLTTSCVSKKVYTDLEDKYANLKKENRALADKNTNLSKSKTTLETDLTKLQKEYDETLAKRNQLQSDYDAAKSNLENLKASYDALEANSSAAITKNADQNRELLAKLEAKEQALAAEGNRLETLKRELEARSQRVAELESVISSKDAQMTKLKNALSKALTNFEGKGLTVEQRNGKVYVSMENKLLFESGSWAVGNKGKQAVKQLGEVLADNPEIAILIEGHTDNVPYNGNTQLSGNWDLSTKRATAIVTILRENGGIRPENLTAAGRGEYAPISTNDSAEGKAKNRRIEVILTPKLDEISKLLNEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGZ8</accession>
    <name>A0A5C6ZGZ8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4301 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08540</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025393">
        <property type="entry name" value="DUF4301"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14134">
        <property type="entry name" value="DUF4301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4301" evidence="1">
        <location>
            <begin position="5"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="525" mass="60106" checksum="0C02E708C6406280" modified="2019-11-13" version="1">MNFSDKDLKQIEQKGLSAKKVKKQMELFENGLPFSNLVSAAILKNGITKLSEKQEANYIDLFEQKKNAISILKFVPASGAATRMFKFLFTFLDDYEPKEESINSYINSKKDSDLSLFFIGLEKFPFYHIVLDQLKEENPNFNQLPINTQLLTFVRAMLDKNQLDYGNYPKGLLPFHEYKNQVISTAFEEHLFESALYSSEGKPTQLHFTISEEHELKFDEEFKRIEDKVEHKTGSKFDISFSYQKKSTDTIAVTPKNKPFRNDDGSLLFRPSGHGALIENLNDLRADIIFVKNIDNVVVYKYKNEVVKYKKILAGVLLEVQESAFEYLRVLDAKALSKLSAEAAEEKIQEIRVFLETKMSVKVSSEFEKYKTRFQVEYLAEKLNRPIRVCGMVKNEGEPGGGPFWVKDENGSVSLQIVESAQINAKNKIQKKILKAATHFNPVDLVCGIMDYKGEKFKLKKYVDHKTAFITKKTTAGKDLKALELPGLWNGSMANWNTIFVEVPLITFNPVKTVNDLLKTTHQIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH12</accession>
    <name>A0A5C6ZH12_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FAD-binding oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_10725</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the oxygen-dependent FAD-linked oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012951">
        <property type="entry name" value="BBE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006093">
        <property type="entry name" value="Oxy_OxRdtase_FAD_BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08031">
        <property type="entry name" value="BBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00862">
        <property type="entry name" value="OX2_COVAL_FAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="2">
        <location>
            <begin position="42"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="468" mass="51490" checksum="3EF5D76E7309A528" modified="2019-11-13" version="1">MKNSAKTIDPQHLKTFAAQLKGKLIFPSDVDYDDARKVYNAMIDKRPGLIAMCEHVDDVIAAVNFGRDHNLLIAIRGGGHNGAGLGVCNDGLVIDLSGIKSVDVDVSNNTVKVGGGTIWNEVDQATHPFGLAVPSGMISSTGVGGLTLGGGVGYLTRKYGLTIDNLLEADMVLADGSFVTVNAKEHKDLFWAIRGGGGNFGVVTSFTFQAHPVKMLIGGPTLWPIEQVEDIMAWYDAFIQEGPEDLTGFLTTMIIPESPFPEALHNKKFCGIIWCYLGEPDKFEAIFKDVLALKPVFAHVGEMSYPALQTMFDGFFPEGLHWYWRADFFNELGPEVSAVHLKFGSAIPTPLSQMHLYPISGAASRVGAEETPWAYRDAKYAGVYLGVDPDPENAAKITDWCKSYYEALHPYSAGGAYSNFMMEEGQERVKASYKHNYERLVKIKTTYDPRNLFRVNQNIKPLEKVSDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH22</accession>
    <name>A0A5C6ZH22_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Isoleucine--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Isoleucyl-tRNA synthetase</fullName>
            <shortName evidence="8">IleRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ileS</name>
        <name evidence="11" type="ORF">ESY86_13835</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl-tRNA(Ile)</text>
            <dbReference type="Rhea" id="RHEA:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:9666"/>
            <dbReference type="Rhea" id="RHEA-COMP:9695"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78528"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="8">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.5" evidence="8"/>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004822">
        <property type="term" value="F:isoleucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006428">
        <property type="term" value="P:isoleucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07961">
        <property type="entry name" value="Anticodon_Ia_Ile_ABEc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02003">
        <property type="entry name" value="Ile_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033709">
        <property type="entry name" value="Anticodon_Ile_ABEc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002301">
        <property type="entry name" value="Ile-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023586">
        <property type="entry name" value="Ile-tRNA-ligase_type2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42780">
        <property type="entry name" value="PTHR42780"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00984">
        <property type="entry name" value="TRNASYNTHILE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="SSF50677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00392">
        <property type="entry name" value="ileS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 8 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNA-synt_1" evidence="9">
        <location>
            <begin position="20"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_1" evidence="10">
        <location>
            <begin position="791"/>
            <end position="943"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="8">
        <location>
            <begin position="50"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="8">
        <location>
            <begin position="704"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="707"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD88175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1156" mass="132500" checksum="1A43D72177482277" modified="2019-11-13" version="1">MSAKFPESKGLDLPKVAENILKYWQEHDIFEKSVTSREGQEPYVFFEGPPSANGLPGVHHVLARAIKDIFPRYKTMKGFQVKRKAGWDTHGLPIELGVEKELGITKEDIGKTISVEDYNNACRKAVMRYTDVWNDLTQKMGYWVDMEDPYITYEPKYMETVWWLLKEIYNKKLIYKGYTIQPYSPKAGTGLSSHELNQPGTYQDVTDTTVVAQFKANADTLPDFLQDEGDIYFLAWTTTPWTLPSNTALTVGPKIEYVLVETYNQYTFEPMNVVLAKNLVNNQFSGKFFEVMSKPELLDYKHGDKKIPFHVVKSFSGKDLVGITYEQLLPYALPNDHAENAFRVISGDFVTVDDGTGIVHTAPTFGADDALVAKQASPEIPPLLVKDEDGNLVPLVDLQGRFRKEVQDEIYGFAGEYVKSEYLSESELTSELKKQQESLESIISNLKSYMSVDERLALKLKNENKAFKVEKYKHSYPNCWRTDKPILYYPLDSWFIKVTDVKERMVELNKTINWKPESTGTGRFGNWLANANDWNLSRSRYWGIPLPIWRTEDGKEEICIGSVEELKHEMQKSVETAFMPSDIYADFEIGNNSEENYAKIDLHKNIVDAIILVSPSGKKMYREADLIDVWFDSGSMPYAQWHYPFQNKEKVEKIWRKADFIAEGVDQTRGWFYTLHAIATMIFDDVAYKNVVSNGLVLDKNGQKMSKRLGNAVDPFTTLDTYGADATRWYMISNTNPWDNLKFDLEGIEEVKRKFFGTLYNTYSFFTLYTNLDGFAYAEDDIPLNERPEIDRWILSELHTLIQKVDDYYADYEPTKAARAISDFTQDYLSNWYVRLSRRRFWKGDYQADKISAYQTLYTCMVTIAKLGAPIAPFFMDKLYLDLNSVTKKEDFESVHLAEFPKFDSAFVNKSLERKMENAQIISSLVLSLRAKEKIKVRQPLQKIMIPFDNDTQKEEILAVADLIKSEVNVKAIEVLEDEAGILVKQIKPNFKVLGPRFGADMKAVAQAVNNFGAKEIKIIEQNGSLEVQINGKSIILERGDVEITSQDIEGWLVASSGRLTVALDVTLTEALRKEGIARELVNRIQNLRKDSGFELTDRISVKFKTDEHIINAIDSNLEYIKTETLTDSLEVLEQLDEGIEIAFDEVNTKLFIEKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH26</accession>
    <name>A0A5C6ZH26_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">General stress protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10835</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038725">
        <property type="entry name" value="YdaG_split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16242">
        <property type="entry name" value="Pyrid_ox_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyrid_ox_like" evidence="1">
        <location>
            <begin position="10"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="166" mass="18697" checksum="A2AE50E89717F4A9" modified="2019-11-13" version="1">MSKTNLYNQEAIDKIKDMAESIDFCMFATRLGQKPFHVIPMSTKKVDLNGHVWFLSGKDSDHNKNIHKDNSVEVMYSKPGDMSFMTIHGTASINTEKSILKELYGSSDDNWFDGLDDPSLTAIQVKPLEAHYWEPKHNKLVTLFKMSVGAFSGEQPDSSEHGDIKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH46</accession>
    <name>A0A5C6ZH46_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">50S ribosomal protein L30</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">rpmD</name>
        <name evidence="7" type="ORF">ESY86_14920</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2 5">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL30 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01658">
        <property type="entry name" value="Ribosomal_L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01371_B">
        <property type="entry name" value="Ribosomal_L30_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036919">
        <property type="entry name" value="L30_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005996">
        <property type="entry name" value="Ribosomal_L30_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016082">
        <property type="entry name" value="Ribosomal_L30_ferredoxin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15892">
        <property type="entry name" value="PTHR15892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00327">
        <property type="entry name" value="Ribosomal_L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002211">
        <property type="entry name" value="Ribosomal_L30_bac-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55129">
        <property type="entry name" value="SSF55129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01308">
        <property type="entry name" value="rpmD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_L30" evidence="6">
        <location>
            <begin position="5"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD87959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="61" mass="6672" checksum="027513D2513F1683" modified="2019-11-13" version="1">MAKKIKVTKVRSAINRAQTQKRTLESLGLNKIGQVKVHDASPSVLGMVNKVSHLVSVEEMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHJ4</accession>
    <name>A0A5C6ZHJ4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">tRNA modification GTPase MnmE</fullName>
            <ecNumber evidence="6">3.6.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">mnmE</name>
        <name evidence="6" type="synonym">trmE</name>
        <name evidence="9" type="ORF">ESY86_11495</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="6">Binds 1 potassium ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer. Heterotetramer of two MnmE and two MnmG subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.-.-" evidence="6"/>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04164">
        <property type="entry name" value="trmE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.430">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00379">
        <property type="entry name" value="GTPase_MnmE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031168">
        <property type="entry name" value="G_TrmE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018948">
        <property type="entry name" value="GTP-bd_TrmE_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004520">
        <property type="entry name" value="GTPase_MnmE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027368">
        <property type="entry name" value="MnmE_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025867">
        <property type="entry name" value="MnmE_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027266">
        <property type="entry name" value="TrmE/GcvT_dom1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12631">
        <property type="entry name" value="MnmE_helical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10396">
        <property type="entry name" value="TrmE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00450">
        <property type="entry name" value="mnmE_trmE_thdF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51709">
        <property type="entry name" value="G_TRME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 6" id="KW-0630">Potassium</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TrmE-type G" evidence="8">
        <location>
            <begin position="222"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="23"/>
        </location>
        <ligand>
            <name>(6S)-5-formyl-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>(6S)-5-formyl-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>(6S)-5-formyl-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="232"/>
            <end position="237"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="251"/>
            <end position="257"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="253"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="257"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="276"/>
            <end position="279"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="470"/>
        </location>
        <ligand>
            <name>(6S)-5-formyl-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD88865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="470" mass="51275" checksum="1B0530A2B43C43A2" modified="2019-11-13" version="1">MTHHDTIIALATPSGNGAIAILRLSGADAIAIADSVFRSVKTGKSLQNQKTHSLHLGHIVEDKRVIDEVLVSLFKNPNSYTGEDVVEISCHGSTYIQQEILQLCLRKGCRMATAGEFTLRAFLNGKLDLSQAEAVADLIASDNEASHQMAMQQMRGGFSSEIAKLREELLNFASLIELELDFAEEDVEFADRSQFKALIERIGFVLKRLIDSFAVGNVIKNGIPVAIVGEPNVGKSTLLNALLNEDRAIVSEIAGTTRDTIEDEISIGGIGFRFIDTAGIRETKDVVESIGIKKTFEKIDQAQVVLFLVSGTQLVSEVEKMESFIVEVEKVRNKFPQKQLIVILNKIDEIGAQDLEALVAALKTHASQLIPISAKTGAGVEELTDALLNLINTGALRNNETIVTNSRHYDALLKAFAEIQMVKEGLETDISGDLLAIDIRQALYHFGEITGEITNDDLLGNIFANFCIGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHS2</accession>
    <name>A0A5C6ZHS2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ferredoxin--NADP reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_07815</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008333">
        <property type="entry name" value="Cbr1-like_FAD-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00970">
        <property type="entry name" value="FAD_binding_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="6">
        <location>
            <begin position="2"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="5">
        <location>
            <begin position="261"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD89678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="351" mass="39002" checksum="8EEBA76D4B19C906" modified="2019-11-13" version="1">MSHFHKLSIAKVTRETSNAVTLNFDVPAHLKADYAYKAGQYITLKTHINGIEVRRDYSLCSSPKSGLLQVAVKEVAEGIFSAHANTHLQVGDELEVAPPKGRFVFEPNDNKTKNIALFAAGSGITPILSIIKCALEEEVLSKVILVYGNKTTEDTMFLKSLLALQKQYHERFSIQFVFSQADEDNAIFGRIEKSTVNYVMKNKHKHIDVDAYYLCGPEGMIFAVKDVLLANDVDENRVHFELFKAAKPIETNDTGITDGKTKVKVMLDDETFDFEMSQNQTILEAALDEDLDAPYSCQGGICSSCIARITEGEATMRQNNILTDAELKEGLILTCQAQPTTETITVDYDDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHT1</accession>
    <name>A0A5C6ZHT1_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">30S ribosomal protein S16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rpsP</name>
        <name evidence="5" type="ORF">ESY86_14080</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the bacterial ribosomal protein bS16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00385">
        <property type="entry name" value="Ribosomal_S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000307">
        <property type="entry name" value="Ribosomal_S16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023803">
        <property type="entry name" value="Ribosomal_S16_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12919">
        <property type="entry name" value="PTHR12919"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00886">
        <property type="entry name" value="Ribosomal_S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54565">
        <property type="entry name" value="SSF54565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00002">
        <property type="entry name" value="S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="144"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="158"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="180"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD88222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="194" mass="20895" checksum="80ECCCFE02454C48" modified="2019-11-13" version="1">MPVKIRLQRHGKKGKPYYWIVAADARAKRDGKYLEKIGSYNPNTNPATIDLNLDSAVKWLQNGAQPTDTARGILSYKGAMLKNHLAGGVRKGALTEEQAEEKFNAWLDEKGNKVQAKTDNLSQADAKAKADALAAEKAVNEARIAAATPVEEPQAEPAAEAEEAKAEGDAEATPEAEATEDATAEDKKEPKKEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHZ5</accession>
    <name>A0A5C6ZHZ5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Rhodopsin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_06205</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="6">Contains one covalently linked retinal chromophore.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the archaeal/bacterial/fungal opsin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010461">
        <property type="term" value="F:light-activated ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007602">
        <property type="term" value="P:phototransduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001425">
        <property type="entry name" value="Arc/bac/fun_rhodopsins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017402">
        <property type="entry name" value="Proteorhodopsin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01036">
        <property type="entry name" value="Bac_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038142">
        <property type="entry name" value="Rhodopsin_bac_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00251">
        <property type="entry name" value="BACTRLOPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01021">
        <property type="entry name" value="Bac_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0157">Chromophore</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0600">Photoreceptor protein</keyword>
    <keyword evidence="6" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0681">Retinal protein</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="52"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="218"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(retinylidene)lysine" evidence="6">
        <location>
            <position position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR038142-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD89795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="246" mass="27531" checksum="357583CE2DA7AFE8" modified="2019-11-13" version="1">MKTMFLFAEVSTKLDPTDYVGFTFFVGSMAMMAASAFFFLSLSQFDRKWRTSILVSGLITFIAAVHYFYMRDYWFANVESPTFFRYVDWLLTVPLMCVEFYLILKVAGAKTSLMWKLIAASVVMLVTGYFGEAVYMDQAAFWGGVSGLAYFYIVYEIWLGSAKKLAVAAGGNILTAHKILCWFVLVGWAIYPLGYMLGTDGWYTSLIGTGSVDVVYNIADAINKIGFGLVIYALATKMQVTQTHNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI01</accession>
    <name>A0A5C6ZI01_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ATP-binding cassette domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_12545</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030296">
        <property type="entry name" value="MlaF/Mkl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43023:SF6">
        <property type="entry name" value="PTHR43023:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD88562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="255" mass="28754" checksum="218FCEB4601E58EE" modified="2019-11-13" version="1">MIEVKDIEKSFGDARILKGISTTFEEGKTSMVIGQSGSGKTVFLKCLLGLFTPEKGEIIYDGRPYSGLSDDQRSDLRAEMGMVFQGSALFDSMNILENVMFPLRMFTKQSKSEMADRADEVLKRVNLEDAHKKMPSEASGGMQKRVAIARAIVNRPKYLFCDEPNSGLDPRTAIVIDNLIQEITEEYNITTVINSHDMNSVMEIGQKIVFLKDGVKAWEGSNKTIFKTDNEAVTNFVYSSDLFKKVRQMYLEERQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI60</accession>
    <name>A0A5C6ZI60_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Lrp/AsnC family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_06410</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00033">
        <property type="entry name" value="HTHASNC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="4">
        <location>
            <begin position="4"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD89831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="154" mass="17708" checksum="87146B9138F419EA" modified="2019-11-13" version="1">MTNLDPIDKMLLKILQNDSKQTNKQLALQLNLSVTAVYERIKKLERAQVISKYVALVDKSKVNKSFVSFCSIKLTQHTQDHVRQFEKEVIKLKEVLECYHTSGDYDYLLKVLVGDMEEFRKFMVEKLTSISHIGSTHSAFMISEVKHTTAISVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIT5</accession>
    <name>A0A5C6ZIT5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nuclear transport factor 2 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12680">
        <property type="entry name" value="SnoaL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="16"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="134" mass="15272" checksum="0CE67AB77EF1238C" modified="2019-11-13" version="1">MSAKSVVQKFLDSDLAKDQETIDLFHKDCKLNWHSSKGFTEIDYNGIASKLKAIQKSYESFTYSYSHILQDGHFVTSRSTIYVTSIERREKEDALAHFISIWEVKDGKLYKGYEISQLADSGSSSLNSFAEIKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIU1</accession>
    <name>A0A5C6ZIU1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cation-transporting P-type ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_05210</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="SSF81660"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="246"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="270"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="681"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="714"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="754"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="790"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="823"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="847"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="domain" description="Cation_ATPase_N" evidence="8">
        <location>
            <begin position="4"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD90148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="882" mass="97168" checksum="621AC6C4AE85972C" modified="2019-11-13" version="1">MMLEPFALSIAAVVEKLNSNLTDGLTENEVKQRIKKHGKNEIAAKAGKTKLKILMDQFNDPIIFILAVAAVLTFFFNDDLPETIAIITVILITVIIGFIMELQGLRSLEALRKMGITESSVLRDGKIKAIKSSLLVPGDIIIIEAGDVVSADARLITIENLAIKEASLTGESRAILKTINSLPKNTTLPDRTNMLFKGTTVEQGSAKAIVVETGLHTQLGKIQQMGSEVEEQRTPLEKKLSELSKWLIWLTLIFAVLIIFTGYLRGQDMLLIIETAVALAVAAIPEGLPVVATIALARGMLKLSKRQVIIKQMEAVETLGATNIICTDKTGTLTEDKMQVHTLVFEDETVTEIQNKAHAYFNELEKSEAFNAMLMTSMLCNNVILNAEELRGDSIELALIQFAEKVHFNPKKVKEEHPEIMEIPFTTESKLMATLNKNEAKGYTVYVKGAFESVIHHCNTILKNNTSEEFKNKKEWISRENDLASQGLRLLAFAFRNHETKPNKNDLLSELTFIGIIGFLDPAREDVASTIKVYKEAGIKVVMMTGDHPGTARKIAEEIGLISTNATSNSIIHGKDLQFEGEHRTNQTKILDASVFARVTPEQKLKLVQLFQENENVVGMFGDGINDIPALRKADIGIAMGIRGTQAAREAADIVLKNDKFTAMELAISQGRAVFDHVRQFVVYLLSCNLAEVVSVGLAALLGLPAPLLPLQILFLNLVTDIFPALALGMGKGEVDIMKRPPRKANEPILTRKLWSSTIIYGISITAAVVGITAYAYFGLEFSAQIINNMAFYTLVLAQLFNVFNMAENKVSFFKNEVIKNPWVWSAIGISLFLTIGAYYIPPVANALFLINLSLEQIGWVIVFALGSLALSQIIKRLGGTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIY9</accession>
    <name>A0A5C6ZIY9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type II/IV secretion system protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_09445</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP E family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00662">
        <property type="entry name" value="T2SP_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SP_E" evidence="2">
        <location>
            <begin position="290"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="468" mass="52834" checksum="E6606E94B11354F3" modified="2019-11-13" version="1">MTEDFQIPTNLLQLLSSEQAHHYRIVPIESHNGTIAFKSDKVSEGLQQELRVVLNTDIELIEDTSENIQNYLSVNFRKSKNIQSENLHYSSDFLDKLLMTAKDIGSSDIHFEPYEHKCRVRFRMDGKLKEQFIIALHEYPVIVNKLKIQAGLDISEKRLPQDGRITVKTVKNEFDIRVSSLPTLHGEKMVLRILSKDATHIDLDALGFTESELRTYKETVRKPNGIILISGPTGSGKTTTLYATLKLLNNDDTNILTIEDPIEYTLEGVNQVQLKENIGLDFSSTLRTFLRQDPDIIMVGEIRDAKTANMAIRAALTGHLVLSTIHTNSAWATISRLIDMGIPSFLIASTLNVSVAQRLVRKLCVHCKQKSTITKELFPSNFEIPKHLKSHFLATGCNACHHTGYQGRKAIYEIIPITKILVQHIKENDLEVDSYLEEHNVSTLRSNAVSMIEEGITSIDEVYALLSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ03</accession>
    <name>A0A5C6ZJ03_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HPF/RaiA family ribosome-associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10965</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD89002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044238">
        <property type="term" value="P:primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036567">
        <property type="entry name" value="RHF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003489">
        <property type="entry name" value="RHF/RaiA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02482">
        <property type="entry name" value="Ribosomal_S30AE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69754">
        <property type="entry name" value="SSF69754"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0810">Translation regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="104" mass="11681" checksum="E0DBBE987CDEE1AC" modified="2019-11-13" version="1">MTIQINTDKTISGEKRTEDFFTSQIEEALERFESHITRVEVHLKDENGKKDGFNDISCLLEARLEGRQPIAVTNQADTIDLALTGAIDKIKNAVESILGKIQKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ78</accession>
    <name>A0A5C6ZJ78_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">5-oxoprolinase subunit PxpA</fullName>
            <ecNumber evidence="1">3.5.2.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pxpA</name>
        <name evidence="1" type="ORF">ESY86_06280</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.9" evidence="1"/>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017168">
        <property type="term" value="F:5-oxoprolinase (ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005501">
        <property type="entry name" value="LamB/YcsF/PxpA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30292">
        <property type="entry name" value="PTHR30292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03746">
        <property type="entry name" value="LamB_YcsF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="245" mass="26865" checksum="3ABDC5B6958E33C5" modified="2019-11-13" version="1">MNSSIDINCDLGEGMGNEASIMPLISSCNIACGAHAGDLATMETVVDLAQRHQVKIGAHPSFPDKANFGRKVMQIPAEELRKSLTFQIESLMTILKQKNGNLHHVKPHGALYNLAAKDEATAKVVVEVVKGFGGNFILYAPYQSVIAKVAKAQGVPVMFEAFADRHYNADLSLVARTHEQALIHNPDEMFAQVYRMVSEGKVRTRDGVEVSMKADTFCVHGDGKNVVENLEHLRTKLMAHHITMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJJ2</accession>
    <name>A0A5C6ZJJ2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter permease subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_09155</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="61"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="213"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="260"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="61"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD89300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="291" mass="32557" checksum="7D21357AE788750E" modified="2019-11-13" version="1">MNLKKHLNSKTLGQLFFIAVVTLPVLSGLVYATLYSLGFVGVLNKGFTTENWEAIFFGSPFWTSILFSFYVAVTSIVLSLVFSLSMALSWKKALQKGALSTAMYLPLCFPGTVMAFFMFQLLSKSGFLSRLGFTAGILSELNQFPALINDAYGIGIIITSVVLITPFFVILFSNMYRSENIANYKQLASTFGATKLQLLTKVTLPILLKKSSVTIYLFVIFVMGSYEIPLLLGRQSPQMISVAILQKIQRFNLYDIPKGFAMSILYVLIIISVLLLLYFRNRDFFKTETNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJN5</accession>
    <name>A0A5C6ZJN5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF349 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_03400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007139">
        <property type="entry name" value="DUF349"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03993">
        <property type="entry name" value="DUF349"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="409"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="647"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="827"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="22"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="50"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="97"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="188"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="242"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="308"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="889" mass="102283" checksum="C3780437CAD3633C" modified="2019-11-13" version="1">MSENDNLHNADGKRVEKVNPQAPDENPTTENKTTETNPVSEPTEETPETTSEDPLGKDVSDQLVERPKDPEAEIPSATEHAESQSEADASNSNASEESTESKEESVPEPSEEPLKTEEIKAEAISEAVSEPEVKHSDNVSEAAPEADEHKEPIVSESKTENTSEEQSETPSEEKTEASSAAVSEPEVKHSDNVSEAATKAEEHKEPIVSESKTENTSREQNETPSEEKTEAISAAVSEPEVKHSDNVSEAAPETEEHKEPIVSESKTENTSEEQSETPSEENKKAPTEAKKIDAHVDEIDQSNAEDAEDEGNSERHTVETKEYEKMTMAQLAEELETLVEQRKVQTIKSQVDEIKSEFNSKFDELLEEKKETFLNEGGNEIDFYYSTAEKKRFNAAYKTYRNNLKAYYKARENDLKANLENRLQIIEDIKGLINVEENINTTYKQFKDLQEQWRGAGPIPRDVYNNAWNSYHHQVEVFYDFMHLNRDLRDMDFKHNLEQKTKLIEKAEELAEGNDVNHAFRELQALHKLWKEDLGPVAKAHRDPIWERFSNATKTIHDKRQAYFTELDKAKEGNLKRKEAIILKIEDVVKDTSNTHQAWQKKIKAIEALRTEFFNSGRVPKPKNEAIWNKFKTTVRSFNSDKNAFYKNLKKDQYENLEKKKELIKIANEHKESDDFAATTPLMKRIQADWKKIGHVPRKDSDKVWKQFKNACNHYFDRISSQRNEADKELLVAYEQKNEFLDGMKTLELSGEHKKDIALIKSKIEDWKNIGAVPSNKRYIEGKFNKVLDALFGKLDMDKSKLEMIKFDNKLENLAQPDDTRLLDNEHNFIRKRIDEVKGDINQLENNLQFFSNVDETNPLVKEVLNNIEQHKADLDLWERKLQMVKKKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJR7</accession>
    <name>A0A5C6ZJR7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RluA family pseudouridine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06245</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140098">
        <property type="term" value="F:catalytic activity, acting on RNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034470">
        <property type="term" value="P:ncRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02869">
        <property type="entry name" value="PseudoU_synth_RluA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluC/D_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PseudoU_synth_2" evidence="1">
        <location>
            <begin position="22"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="234" mass="26461" checksum="3B37EFBB8C077B0D" modified="2019-11-13" version="1">MSKFVVKHSDKNNLQVLYEDNHIIIVNKRAGDIVQGDKTGDKPLSEVVKSYIKDKYNKPGKVYLGVVHRLDRPTTGIVMFAKTSKALPRLNKLFAEKKTNKTYWAIVKNPPVKTEDTLLHWLKKNPKNNKSAAHHKEISDGKKAILHYTTLKTLDNYTLLEVTLETGRHHQIRVQLASIGSPIKGDLKYGFNRSNPDGSISLHARRLQFVHPVSNEAIDIEAPLPEDAVWNACL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJT8</accession>
    <name>A0A5C6ZJT8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Alanine--glyoxylate aminotransferase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_03660</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3 5">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024169">
        <property type="entry name" value="SP_NH2Trfase/AEP_transaminase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000524">
        <property type="entry name" value="SPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="6">
        <location>
            <begin position="28"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="3">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000524-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD90474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="390" mass="42595" checksum="A555416715DE4AC4" modified="2019-11-13" version="1">MKGRKLLMIPGPIEFEPDVLHAMGIATTSHVAPNFIEVFGNSLELMRAVWKSPKGQPFIVAGTGTLAMDMAAANLIEQGDHVLVISSGYFGKRFRDILDRYGANTTLLEAALGEVVSLEAIENELKTKSYKALTITHVDTSTGLLVDPKPIALLAKKYHTLSILDGVCSVAGEALHQDEWELDVVLTASQKAIGVPPGLALLMASEKAIQVWENRKTPVPNYYADWTNWLPIMRAYEERRPSYFGTPAVNLVVALETSLKIICKEGMDKRVKRHRSLAKAFRAGIASLNLSILPKTNKTAANTLTAIYYPKGIDDLAFRSKMASDDVIIAGGLLSEIKTQYFRIGHMGSVSASDLVAVLAALERTLIALGHPLESGKSLQTFQKEHLKTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJX6</accession>
    <name>A0A5C6ZJX6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transcriptional repressor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_04915</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002481">
        <property type="entry name" value="FUR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33202">
        <property type="entry name" value="PTHR33202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01475">
        <property type="entry name" value="FUR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="138" mass="15486" checksum="6D4EA3FF5312E111" modified="2019-11-13" version="1">MTEIEKTLEAHQVRPTAMRILIYKYMAEKEVAVALTDIESAFSKSDRSTLYRTLKTFEENGIAHQIDDGTGISKYALCESGCNCELDQDLHLHFHCSNCDETVCLTAHKIPHINLPYGYLAENANLVVKGICEKCSSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK60</accession>
    <name>A0A5C6ZK60_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Mechanosensitive ion channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_07015</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011066">
        <property type="entry name" value="MscS_channel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82689">
        <property type="entry name" value="SSF82689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="55"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="78"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD89942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="300" mass="34153" checksum="3876D74BCD5CAD5C" modified="2019-11-13" version="1">MKSAQDWLNENPVIYSIIKYLLIVAAVLICIHFIRKVLKRNIPNTSVRYKSQKGIEILGYFIIIILSVSYFTGNIKDFTIAIGLFSAGVAFTLQELILSVAGSLYIFIVKVYAPGDRIELHGIKGDVIDVDSIYTTMMEIGQWVESDNYSGRIVKLSNSFVFKGPIYNYSKDFPFIWDQFSLPIRYGSDMELAKSIVINIASETLSEYTRASKVQWESIVAKYYIEAAEVEPTLAVTLTENWVQFNLRYIVDYKRRRSTKNMLNESILKAFEQTKGKVVLGSTTVELIKIPDLKVDVNKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK95</accession>
    <name>A0A5C6ZK95_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_05850</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023121953" evidence="3">
        <location>
            <begin position="22"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="373"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="5">
        <location>
            <begin position="619"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="668"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD90259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="743" mass="84644" checksum="B811B289B0DFDFBD" modified="2019-11-13" version="1">MSKSNNFISIFFMLLACVSFAQDLDTEDPEVLKLRMENNMLQSEFDIGHGNYFNAKDNLERAMALAIRIEDKKSEGFIHTRIGKLQHTVKEFDKAFVSLTKAAEIQRELNDYKNLAITYSIRGSLHASKNEYQNALDYYNSAKTLFHEHDLEKLSTEVMLNEAKIYYELEEYDNSKVLLDEVIENATQFNQKNTLSSAMIYNGKTLNRLNQEDLAITAVSEGLSLAKSNDYLETINEAYLTFNEIFQKKEDYKAAHNYLLKHMQLSDSILNVERKNLTPESRAAYLEAYSIADYEKMKKQLEDIESESSLSRITTILSIALISILSLLTLALYKNNNIRLKSNNMLLEKNDDLVEAMRLAELASKTKANFLSTVTHELRTPLYAVTGLTNMLLEEEPTKEQIPHLKSLKFSGDYLLQFINDILQINKIEANKVDLDPILFNLKTKVENVCSALNNSALDNNVILHYEFQKDLEETFIGDNLKISQILINLIGNSIKFTKDGDIWVRVYSISKNGNEHLIRFEIEDNGIGISKEKQEHMFESFSQGSIQINRKYGGTGLGLSIVKGLIDILKGNIYLKSDLGKGTTFFFEIPLTYAPESVKIEKVDYSKNISSLDIKNIKILIVEDNKINQMITKKILTKMNLECEVVDNGEDAVEKVRENRYDVVLMDIHMPGISGLEATKIIRGFDKTLTIFALTAVTLEDKMHEFDEAGFDDIISKPFKQEDFEKKLFDTLSSNANTIASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK99</accession>
    <name>A0A5C6ZK99_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase family 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_04505</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="4"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="294" mass="33890" checksum="EDCB004ED349736C" modified="2019-11-13" version="1">MDISIIIINFNSSTFTIGCIESIHRHTKTVSFEIIVVDNNSSSKDLLILETYLENSSVKLIKSKVNLGFGGGNHLGYQFASGKHYAFINNDVELTENSLLKLLQYSNAHPDIGVLGLHQVNAEQKQFRYSYRQFIGFNYHFFNQKKPQAYYGRLTNSDLSKPFEVDIVSGAFMFFKKVAYEKAGGFDPNIFLFYEEMDVCLRLKKAGYKTVFYPESTFIHFMGKSSTNVKIRAEFTISYLYVIQKNFTYSYFCAMRLMLLLKYGFKSILKPKKYYAPFKILLRGGNSLVYSMKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKD5</accession>
    <name>A0A5C6ZKD5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sigma-70 family RNA polymerase sigma factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_05865</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="23"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="3">
        <location>
            <begin position="129"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD90262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="183" mass="21541" checksum="F23FB1DC54B44CC2" modified="2019-11-13" version="1">MEIKQAIERAKNNDQMAFSFLLDRFWNDVYGFQLKRTENENDAEDITIQSFSKAFDKIETYNSDYEFKTWLIAISKNLHIDLIRKKKSIISSTSANNDEEDYYGVIDDSPSPEDQLITEQNLKKLLRDIKKLKPHYQDVINLRYFQELTYKEIAAHLDEPISNIKVKLLRSKKLLAEIIKKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKH5</accession>
    <name>A0A5C6ZKH5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Y1_Tnp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_06080</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1290">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002686">
        <property type="entry name" value="Transposase_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036515">
        <property type="entry name" value="Transposase_17_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM01321">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143422">
        <property type="entry name" value="SSF143422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Y1_Tnp" evidence="2">
        <location>
            <begin position="21"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="103"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="269" mass="32388" checksum="4168C4BFA6649E70" modified="2019-11-13" version="1">MKLFKNKYRIDSTRLKSWDYGSDGYYFITICTKGRRHFFGKIDRQHMHLSAIGQLAEIFLNEIKTQFSYARMDEYVVMPDHIHCIITINNPSRRDAIHRISQNTEHQHTEHQHTEHQHTEQQHTEQQHTEDQRTEEKQTEEKQTGDQHIEDHQTEAHQTEQQTEQNQLEIKELKNTKKMLIVNEIKMDKGGFTKEQNPMLHDNVSKIVRWYKGRTTFESRKLGLDFAWQPLFWDHVIQNERALNNIRDYIQNNPKKWEKDKQNNPGLKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKI9</accession>
    <name>A0A5C6ZKI9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">M24 family metallopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_03885</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007865">
        <property type="entry name" value="Aminopep_P_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_NTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05195">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01011">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="SSF53092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0464">Manganese</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP_N" evidence="3">
        <location>
            <begin position="28"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD90516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="492" mass="55395" checksum="5EE552B1D6B2985E" modified="2019-11-13" version="1">MKLFQTLILLISSCSIGFSQRGLPEDYLSAQFHKERRTELRNRMPANTVAVFFANAVRNRANDVDYVYHQDPNFYYLTGYKEPHAVLIVFSENQQDPDGTKYNEQLYVQERNARAEQWTGRRLGVEGAKAQLGFESAFNGSEFLNSKIDFSKYDKVMFTDFRDDYRDTRDKADLFDLVHSFKRQIQLIDDYKIENTTNDPEINDNANIKAEAVKTDTKSLSTLMAGLREIKTKAELVLLKKAVRISAMGQREIMKAMHPGMSETEIQGVHEYIYKKYGSEYEGYPSIVGAGNNGCVLHYIENSKTKVENDLVLMDLGAEYHGYTADVTRTIPANGTFNKEQKLIYDLVYEAQEAGIEACVVGASFQMPDAAARAIIYKGLVDLGIAKHESDARQYFPHGSSHHIGLDVHDPGLYRALEANMVITVEPGIYIPEGSDCDPKWYGIAVRIEDDILITAVGPENLSAEAPRSSSAIEKLMKEKSVLNALDLPNLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKR1</accession>
    <name>A0A5C6ZKR1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ergothioneine biosynthesis protein EgtB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_02905</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052699">
        <property type="term" value="P:ergothioneine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1580.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024775">
        <property type="entry name" value="DinB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017806">
        <property type="entry name" value="EgtB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005532">
        <property type="entry name" value="SUMF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042095">
        <property type="entry name" value="SUMF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12867">
        <property type="entry name" value="DinB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03781">
        <property type="entry name" value="FGE-sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="SSF56436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03440">
        <property type="entry name" value="egtB_TIGR03440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DinB_2" evidence="2">
        <location>
            <begin position="7"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="FGE-sulfatase" evidence="1">
        <location>
            <begin position="169"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="381" mass="45123" checksum="05DA7069D2EE65E5" modified="2019-11-13" version="1">MNLETAYTETRNRFVNICKGLKTEDYSVQPAIFVSPPKWHLAHSSWFFEQFVLVKYLQGYEIYDEDFSYLFNSYYNNAGKRVLRPNRGLMTRPAVDEVYRYRKHVDQHMRRFFAEKPSEAAKAVILLGLQHEQQHQELFYYDIKYILGNQPTFPKLKQHLQLKEISSKANWISIDKGLYAIGHQGDGFCYDNELGQHQVHLEAFQIRDQLVSNAEYLEFMEAGGYSDFNLWHAEGWDFIQQDQIEAPAYWHKVDGIWHNYTFDGFVKVHPKQPVMHLSFYEAFAFAEWKQMRLPTEFEWEVASKHLNYGQLWEWTYSAYLPYPNFTKAPGALGEYNGKFMINQMVLRGASVATYANHSRATYRNFFHPQLRWQFAGLRLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL19</accession>
    <name>A0A5C6ZL19_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sterol desaturase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_03900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006694">
        <property type="entry name" value="Fatty_acid_hydroxylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04116">
        <property type="entry name" value="FA_hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid hydroxylase" evidence="2">
        <location>
            <begin position="100"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="328" mass="38604" checksum="A07D66E14852E910" modified="2019-11-13" version="1">MDFTNPLIYGVPCFLGLILLELTYSKTHDHKNNKDLYKWKDFASSLTMGIGSGIIAPLIKTISAIVIFNFLYEIFNPEINGIRTNIMGYESFGYAWYVWLICQFLDDFTYYWFHRQNHMVRFLWAAHIVHHSSDNFNLGTAVRNGWFTILYKPLFYMWLPIIGFPPEMVVVCLGIEALWQFQLHSVYVPKMGFVEKIFNTHTMHQVHHAKNLEYMDKNHGGFLNVFDKVFGTWKALDENIEIEYGVTKPPNSYNPLVILTHEYKDIWNDMKKSKNWRHKFMYAFGAPGWSHDGSTLTIKQMREKIKKEQKMQVSEKKSSKLVLERQGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL69</accession>
    <name>A0A5C6ZL69_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">3-deoxy-7-phosphoheptulonate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_02115</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004106">
        <property type="term" value="F:chorismate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046417">
        <property type="term" value="P:chorismate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.59.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036263">
        <property type="entry name" value="Chorismate_II_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036979">
        <property type="entry name" value="CM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002701">
        <property type="entry name" value="CM_II_prokaryot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006218">
        <property type="entry name" value="DAHP1/KDSA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01817">
        <property type="entry name" value="CM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00793">
        <property type="entry name" value="DAHP_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00830">
        <property type="entry name" value="CM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48600">
        <property type="entry name" value="SSF48600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51168">
        <property type="entry name" value="CHORISMATE_MUT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chorismate mutase" evidence="1">
        <location>
            <begin position="267"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="360" mass="40629" checksum="4F677864D4DEB919" modified="2019-11-13" version="1">MENKKELRGWLDNFGLNHPLVIAGPCSAETEAQVLKIAHQLKESDATVLRAGIWKPRTRPGNFEGVGALGLKWLQKAKQETGMLTTTEVANANHVDLALKHDVDILWIGARTTVSPFIVQDIADALKGTDKIVLIKNPVNPDLALWLGAVERFHTADVKNLGVIHRGFSTYEKTRYRNNPEWQIAVDLQNRFPDLPLILDPSHIAGRRDIIFDLCQTALDLNYDGMMVETHYDPDNAWSDAAQQITPETLIQITKDLKIKKETAEGADYNNKLNTLRTQIDVVDHQLIDMMGKRMKVADEIGALKKTKNVAVLQTKRWNEILGKMILQGEEKNLSEEFILRVFKAIHQESINHQEKVING</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLD8</accession>
    <name>A0A5C6ZLD8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00790</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="29"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="96" mass="11058" checksum="22000B920F9E9EF7" modified="2019-11-13" version="1">MSKIEAIVDSLEHKIGEVLQRQDVLKQANASLTQELVIEKQKNLELQEQIEVWTEKHETLKIANSLLGSDENNRETKLKINTLIRDIDYCIAQLSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLH8</accession>
    <name>A0A5C6ZLH8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="331"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="471" mass="54843" checksum="58203AA1EC2DD269" modified="2019-11-13" version="1">MKFYVVAFLTASLLLSCDGKSKDKNIVYLGGQIVNPNNNYITLSNPNTEKDTIFLDQNNRFSYQIKDLTPGLYTFTHGGEMQTVLLEPRDSLLFRLNTNDFDESLVYTGKGSKKNNFLIQAFLRDEIENKAFKNSHQLEPEAFEKHLDSLKSLKQKNLDRFYASYETSELFYKIADAGIAYNYYAYKEMYPFGYYGNNKLIHVKDLPDGFYDYRSNVNFNDINLTGVYAYNNFLNWYFHNTALKKYYHNGQHLAFNRQALDYNLEKLRLIDSVIENETIQNYVLKYATREFIFNSSSANESLAMLDSYIEKSTDLNDKTYLTNLASSTIKLYPGNKLPEIDVVDYNSNTRKLSALIKRPTVIYCWSSNFKMHYRNSHYMMRSLKARYPEMDYIAININDMNSSSWKKTLEQLEYPTENEYLFKNPNEAVQTFAIAYSHKVILVDADGILIESNANLFSPNIAESIEKLIKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLK6</accession>
    <name>A0A5C6ZLK6_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NH(3)-dependent NAD(+) synthetase</fullName>
            <ecNumber evidence="5">6.3.1.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">nadE</name>
        <name evidence="7" type="ORF">ESY86_01985</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + deamido-NAD(+) + NH4(+) = AMP + diphosphate + H(+) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:21188"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.1.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; NAD(+) biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the NAD synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.1.5" evidence="5"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00253"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003952">
        <property type="term" value="F:NAD+ synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008795">
        <property type="term" value="F:NAD+ synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00553">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022310">
        <property type="entry name" value="NAD/GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003694">
        <property type="entry name" value="NAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23090">
        <property type="entry name" value="PTHR23090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02540">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00552">
        <property type="entry name" value="nadE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD_synthase" evidence="6">
        <location>
            <begin position="7"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD90755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="262" mass="29244" checksum="830375C16D2CC06B" modified="2019-11-13" version="1">MKTEKVVDHIVNWLKEYAQNAKVKGFVIGVSGGVDSAVTSTLCAKTGLETLCIEMPIHQAESHVSRANEHIAFLKKTFSNIKEWRVDLTPVFEEFKTEVSLEAHEDIVNMALANTRARLRMTTLYYYAGLHGLLVAGTGNKVEDFGVGFYTKYGDGGVDLSPIADLMKSEVFELAQFLKVPESIINAAPSDGLFGDSRSDEAQIGASYPELEWAMNSKDNGKTAVDFKGRKREVFEIFMTYHQNNQHKMLPIPICEIPKNFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLT8</accession>
    <name>A0A5C6ZLT8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF983 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009325">
        <property type="entry name" value="DUF983"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06170">
        <property type="entry name" value="DUF983"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="131" mass="14959" checksum="C62C51EA209C5D7E" modified="2019-11-13" version="1">MMFQGTKIYSIFTGTCPKCQQESMYKTSNPYVLRDVLTMYSHCAHCKFRYRLEPAFFYGSMYVSYGVGVAFATAAFVITHLFLGLTLTAAFIAIVITLIAFGPIIMRLSRNIWINMFVNYNKELAEKGKQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLV8</accession>
    <name>A0A5C6ZLV8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_01520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="117" mass="13437" checksum="C7C8B370D7D0CC40" modified="2019-11-13" version="1">MNNPWHLYLMAAIYVLAGLIHFIKPKIYLRIMPRYLPSHKLLVALSGIAEIVVGIGLCFEETRTIAIYAIISMLAVFLLVHFYMLSSEKAGAGIPKWLLLLRIPLQFGLMYWAWVYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLW4</accession>
    <name>A0A5C6ZLW4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Penicillin-binding protein 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_05805</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005311">
        <property type="entry name" value="PBP_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036138">
        <property type="entry name" value="PBP_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03717">
        <property type="entry name" value="PBP_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56519">
        <property type="entry name" value="SSF56519"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PBP_dimer" evidence="3">
        <location>
            <begin position="46"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="2">
        <location>
            <begin position="247"/>
            <end position="577"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD90251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="648" mass="73367" checksum="5BB9DF5210D9963E" modified="2019-11-13" version="1">MRKLLLFITVITVGLLFIARLFYLQIYTENTDALYEDNAIRKVYDYPKRGYVYDRNGKLLVANQPSYDVMVIPREVMPLDTLEFCALLKITKDYFIETFNKANHYSPRLPSPFVPQLSKQDYAALQEKMRKFEGFYIQKRSIRDYQTSIGANVLGDLGEVNQRTIENKPYYNLGDLIGKQGIELSYEEVLRGVKGIKFIQKDRFNKNIGPYKEGIYDTLPKPGKDITITIDAELQKYGELLMTNKHGGIVAIEPSTGEILAMVTAPSYNPNLLVGRQRNKNFSKLFLDKRLKPTFDRGLQAQYPPGSPFKVMNALIGLQEGVIDTNDTYPCRMGYYYGSQKLTGCHSHPSPLAMNGGISQSCNAYFVNVYRRIIDKYKDPGKGMNVWANHAKSFGLGNFLNNDLAVGQPGRIPDGDYYDRAYGDNRWGSTYIVSNAIGQGEVETTPIQLANMVAAIGNRGYYFTPHIIKNIEGSEIDSTFTKPKYTTIDKQHFEPVVQGMFDVYNEGTATSLRIPGIDICGKTGTAENFMKIDSVKTQLTDHSIFVAFAPKDNPKIAIAVFVENGYWGSRFAGRIASLMIEKHINGNITRTDMEDWILTHSLEDEYLKPYSGEPFKINRETTLKVVPNVKDHPVDHFALEFETNQPLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM31</accession>
    <name>A0A5C6ZM31_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 13">Tetraacyldisaccharide 4'-kinase</fullName>
            <ecNumber evidence="3 13">2.7.1.130</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 13">Lipid A 4'-kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13 14" type="primary">lpxK</name>
        <name evidence="14" type="ORF">ESY86_05845</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 13">Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 13">Glycolipid biosynthesis; lipid IV(A) biosynthesis; lipid IV(A) from (3R)-3-hydroxytetradecanoyl-[acyl-carrier-protein] and UDP-N-acetyl-alpha-D-glucosamine: step 6/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the LpxK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.130" evidence="3 13"/>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00359">
        <property type="reaction ID" value="UER00482"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009029">
        <property type="term" value="F:tetraacyldisaccharide 4'-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00409">
        <property type="entry name" value="LpxK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003758">
        <property type="entry name" value="LpxK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42724">
        <property type="entry name" value="PTHR42724"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02606">
        <property type="entry name" value="LpxK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00682">
        <property type="entry name" value="lpxK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 13 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 13" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="5 13" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11 13" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 13 14" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="47"/>
            <end position="54"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TXD90321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="336" mass="38426" checksum="EE19B3EDE3C096CF" modified="2019-11-13" version="1">MKLLRKLLLPIVPFYYAITWLRNKGYDWGWKTSKSYDLPVICVGNLSTGGTGKTPMIEFLIRLLKTDYSVATLSRGYKRETSGFVLASENASARTLGDEPFQFYSKFKDITVSVDANRQNGIERLLKLKQPDVILLDDAFQHRKVTAGYNILLTGFGSLYSDDIVLPTGDLREPRSGAKRANMIVVTKCPPNLSEIKKQEIIAALKPSIEQKVFFSSINYSDAIYNEVGRKAFKQLKNKKVTVVTGIANPDPFLNFLRSEQIDFEHLNFKDHHDFTAEEIAVLKQKQCILSTEKDYVRLKPHFASTPTQLYYLPIFFEIDRAEAFERCIKQFVKPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM50</accession>
    <name>A0A5C6ZM50_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">T9SS type A sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_02110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Por_Secre_tail" evidence="1">
        <location>
            <begin position="139"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="215" mass="23466" checksum="CAF018D29DCC069D" modified="2019-11-13" version="1">MKKTLLIVSVLMSLSIYGQTLIKGTVYDPNGALPLANILVKHSTKGTATDHEGRFLISAKPADTLIISYLGFATKHIPVGQAESITVVLDEYEALDEVVIYGFGSRTMSCHTIQCSICCMVAHDSSEAQELKESPKTKLFPNPSKDGFFQIKTEAPFSELKVIVANISGRIISEENYDASNAKLWIDLSNEAAGIYLVNLYAEGEKIASKKAIIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMA4</accession>
    <name>A0A5C6ZMA4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase family 4 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06155</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="1">
        <location>
            <begin position="107"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="428" mass="48881" checksum="0895A1C203C7942A" modified="2019-11-13" version="1">MEKVLIITYYWPPAGGPGVQRWLKFVKYLPEFDLEPVVFCPLNPSYPITDESLLKEVSEAVTVIKQPIKEPYRFAELFSKKRSKSISSGMIPKEKKQSLVEKLLLFVRGNFFIPDARKNWVKPSVAFLKNYLQEHQIDIVITTGPPHSLHLIGRKLKQDLGVTWLADFRDPWTTIGYHKKLKLTSSAKEKHLKMEASILHDADQIIVTSENTKEEFQQKTETPIAVITNGYDTQHSISIEKDKTFSLAHIGSLLSGRNPIVLWEALSELIEEIPNFKSVFELKLIGLVSEEVLQTLTDFGLEPYVHDLGYVPHDQAQKAQRESQILLLIEIDSEDTKVIVPGKLFEYMAANTPILAIGPTDSDVEQILKKTNTGHYFYYAEKQKIKYQIQQYFEAYQANDLSVNAIGLQQYSRKSLTQQLAVLVKNQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMC0</accession>
    <name>A0A5C6ZMC0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_03540</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00614">
        <property type="entry name" value="CGS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808">
        <property type="entry name" value="PTHR11808"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00868">
        <property type="entry name" value="CYS_MET_METAB_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD90451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="392" mass="43406" checksum="6DDB090B2541D7B3" modified="2019-11-13" version="1">MPKKTLGLNTICTHVGEIEDKQFKGAISPIYMSTSYEFDDVEVKRYPRYFNTPNQEHLAKKIAALEHTEAALIFGSGMAAISTMFLAFLKQGDHIVVQNTLYGGTSNFIREEFPKYGIEFTFTNGYQVADFEAAIQENTKVIYIETPSNPLLTITDIKAVADLASSKGLVSMIDNTFASPINQTPIDFGIDLVMHSATKYLGGHSDILAGAVAGSSEHMHRIWNVAKNLGGSLSDMTVWMLERSMKTLALRVKAQNKNALKMAKFLNKHDAVANVFYPGLKTHPEHALAKSQMKGFGGMLSFELVEGIDAIQFQKQLQIIKSSMSLAGVESTMLLPCKTSHALLSSEQREAIGISDRLIRFSVGIETFRDLKQDISQAIARVEKSEKQMEKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMC7</accession>
    <name>A0A5C6ZMC7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NAD(P)/FAD-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_04095</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NADH dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003954">
        <property type="term" value="F:NADH dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006116">
        <property type="term" value="P:NADH oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045024">
        <property type="entry name" value="NDH-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706">
        <property type="entry name" value="PTHR43706"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="371"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_2" evidence="3">
        <location>
            <begin position="5"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD90557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="432" mass="48620" checksum="057456FA09751010" modified="2019-11-13" version="1">MKEKHIVIIGGGFAGVHLAKELAGKKGVKVTLVDRNNYNFFPPLLYQVATGMLDISSISIPFRALFKGKKNLFFRLGEFEEVFPEANKVKLSTGELHYDALVIATGTVSNFFGMENIEKNALPMKTVNEAIKLRNYLIMEGEKYTYCTDEDEKRKMRNIVISGAGPSGVEIAGMIAEMRKRTLRDIYPELIDEQLNIYLVDAAPTVLPPMREKSQTYTKKSLEDMGVIVKLNKMVSDYKGDKVYFKDGETIETKTLIWTAGVTAMKYKGMPEDSYEKGNRLTVDAFNLIAHTKNIYAIGDACIQKTDPEFPKGHPQLGAVAQQQGKALAANFLAMVEHKERDPFRYNDKGAMAIIGDQKAVADLTTPKTTLTGWLAWISWLFVHLYLLVSYRNRFRTFWNWFNAYLGKGQSQGIMIGRTATDTTALEPKNEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMV6</accession>
    <name>A0A5C6ZMV6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA polymerase sigma factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_02010</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="28"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="3">
        <location>
            <begin position="121"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD90760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="189" mass="21953" checksum="40E26E157838CE47" modified="2019-11-13" version="1">MKVIHLHHNNIDLIKKAAKGKRDAQQALFNTHAAKMLSVCRYYIKDIHNAESVMLKAFLKAFKNLNEFENKGSFEGWLRRIMVRESISYLRQSKQVLFSLDEVQLPAEYYNNIDSQIEVAQIQMLIDALPEGYRMVFVMYAIEGYKHDEIAKMLKITVGTSKSQLFKARQMLQKQIKELNSSSYGTNKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMX8</accession>
    <name>A0A5C6ZMX8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_01015</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="291"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="7"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD91199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="337" mass="37891" checksum="2DADB482B2E58658" modified="2019-11-13" version="1">MVSLDFSFIIPVYNRAEEVEELLRSFVNLQGDAAFEIVIVEDGSTMDCKTVISNFETSLNISYYQKPNSGPGDSRNFGMRKAKGNYFIILDSDCILPSDYLIKVTQSLNHRFVDCYGGPDAAHHSFTNLQKAINFTMTSLVTTGGIRGGNAALKNFQPRSFNMGLSKAAFLASGGFGSIHPGEDPDLSIRLNTLGYETALFPKAFVYHKRRLSWSKFYKQVYKFGLVRPILNTWHPKTAKWSYWLPSAFSLGFLAAVILMLFGYWLPIMVYVVYVMTAFILALINSKSLSVAFQSILAIFIQFFGYGLGFLKSSFAIKVMKQAPQSRFPNLFFDNVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMZ1</accession>
    <name>A0A5C6ZMZ1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AAA family ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_00035</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038729">
        <property type="entry name" value="Rad50/SbcC_AAA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13476">
        <property type="entry name" value="AAA_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_23" evidence="2">
        <location>
            <begin position="5"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="345"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="467"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="746"/>
            <end position="773"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD91025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1010" mass="113374" checksum="BDD37B1C5CBF3C64" modified="2019-11-13" version="1">MKISKISFKNIHSLRGEHEIDFLSGPLAESGLFAITGATGSGKSTLLDVITLALYNQVPRIGAISKSVIDGEGGIMTRNAQDCYAEVEYIVNGKTYRSHWSIERNRNNNLNDRKQEIIDVASGNLIESGKSSVPTKNAELIGLSYDQFVKAMVLSQGQFSKLLQAKRDVRNKLLEDITGAKDYRAIGAAVFQKYKNASEVYKVQDIRLKEIELIPEAIRKDLSEQEATLSKAKISQKKALDVLKVEIDTKKGILKNETILAENELLQKELTIAIAHFKNDEETLKKHSKYVVHAALISDFERNDKEHKQTAEELARQQTNETKVLNDRRSLLAQASNLLGKPVAAQNYSEALEQLRKAVTQLKQEESLATTQAKLHEDQTKKTLVDINKDANRIAFNAEPNVFNTLIHPIEEKIDAFLNTSKINTELDLAEKEALLKSKSDLVNTLKLELTAYHSELKTKTSKQADLRQSEALFKTHESKLKVLEAELKLLETEVDTLTKAEENRKAHQSLEAHRSLLVDGEACPLCGAQEHPFSSNTPIFDLQEAALKSKKELLNTKRDLKASTQANLNNEVKNIRDLNRDIIAINALIQPKYTAIETLCKNLQIEVVQNIEGLEAIESRLVNDSKTTDKLKKAFELRHSLKNLKETTALWIKSADLKTTKQTERKKLYPGEDIDAKVQTLTNNWTATNQNIKNTSELIAKLKKKAQQFAEAGEGFQKQLQALLKNEGIENVGQLKTFILSEAKAEDIRQRKKTLDLKQERLKTEKEGAQKEIGSFKKLTTSKEPVDALQLKFAKIEEEYGSLGERIGSIKTKLEADKKAKEKQEDLLNTLKSLKKEETLWKTMNQLIGDAHGKRFSNFVQDLTLEQLIGYTNMRLKDLSDRYILDIPTADEASKNDSLKVFDSHQGDARRSINTLSGGETFMVSLAMAFALSDLAAKNVKIESIFIDEGFGTLDPETLNQAITILEKMQNEGDKSIGIISHVEALKERISTQIRLEKMGSGYSTIEIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMZ4</accession>
    <name>A0A5C6ZMZ4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glutamate synthase subunit beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_02295</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00158"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016639">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006537">
        <property type="term" value="P:glutamate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028261">
        <property type="entry name" value="DPD_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006005">
        <property type="entry name" value="Glut_synth_ssu1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14691">
        <property type="entry name" value="Fer4_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01317">
        <property type="entry name" value="GOGAT_sm_gam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0314">Glutamate biosynthesis</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="36"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD90810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="488" mass="54254" checksum="5345934EDDF4740E" modified="2019-11-13" version="1">MGKVTGFLEYEREDEPYVKVETRVKNYQEFTIPLEEKAMKDQGARCMDCGIPFCHSGCPLGNLIPDFNDKVYKGRWKEAAQILHATNNFPEFTGRLCPAPCEEACVLGINEDPVSIENIEKIIAERAFEEGWITAHPPKIRTDKKVAVIGSGPSGLAAAQQLNRAGHEVTVFERDSKVGGLLRYGIPDFKMEKKVIDRRLAILEEEGIHFKTNAEVGKNISVETIKADFDAVVLCGGATVRRNIPIKGNHLKGVYQAMDFLKPNNQYVDGLLELKDIVSAKDKNVIVIGGGDTGSDCIGTSNRHGAKSVTNFEILSKPSEGRPAHQPWPYWPMRLKTTSSHQEGVERFFSVSTKEFIGDKNGNLVALKTVEVEWILKQGERPELRELEGTEKQWECDMVLLALGFTGAEKTLADQFGLEMDFRTNIKATIKDYATNVKGVFAAGDMRRGQSLIVWAISEGREAAYHVDSYLMGSSNLPRKDEGDLPRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN23</accession>
    <name>A0A5C6ZN23_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF4174 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_02505</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025232">
        <property type="entry name" value="DUF4174"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13778">
        <property type="entry name" value="DUF4174"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023031611" evidence="2">
        <location>
            <begin position="21"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4174" evidence="3">
        <location>
            <begin position="23"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD90850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="143" mass="16785" checksum="29969DB8797CA338" modified="2019-11-13" version="1">MKLKTIILLMLISTANFMEAQDLKKHRWRQRVIIILTENRDNALFNEQVSELEKHLNGLEARKLIVYQLSPKSYKINFSEANQWIENTSLYENFSKTELPFQVLLIGLDGSIKLRQAKLLSAASLFETIDAMPMRRTEMRRKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN33</accession>
    <name>A0A5C6ZN33_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Dihydrofolate reductase</fullName>
            <ecNumber evidence="3">1.5.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_02560</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 5,6,7,8-tetrahydrofolate from 7,8-dihydrofolate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dihydrofolate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.3" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00158"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004146">
        <property type="term" value="F:dihydrofolate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006545">
        <property type="term" value="P:glycine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00209">
        <property type="entry name" value="DHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025698">
        <property type="entry name" value="2TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012259">
        <property type="entry name" value="DHFR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001796">
        <property type="entry name" value="DHFR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48069">
        <property type="entry name" value="PTHR48069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13239">
        <property type="entry name" value="2TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00186">
        <property type="entry name" value="DHFR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="SSF53597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51330">
        <property type="entry name" value="DHFR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="32"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="DHFR" evidence="5">
        <location>
            <begin position="148"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD90860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="309" mass="35513" checksum="85C0FE9B572D5009" modified="2019-11-13" version="1">MFGKKKPIPQIDKTQLALIKNAERRIKQKKRLYIHFVIFLIGSVLLIVANTVLNIGQEFKIFGLDWFVIAIIVWFVLFIYHFISVFIINKFMGRDWEDQQRDLLVAKQEERIEKLKQEYLAKESKVAKSQAFDASAKSSAPFQKKKSELTLIAAAGEDNGIGKDGDLIWHLGDDLKRFKNLTSGHCIIMGRKTFESFKNPLPNRTHIVITRQDNYAVPSGVIVVHNLDDALDAARKDAQPFIIGGGEIYRQAIGMADKIELTRVHGNFPTADTFFPEIDGFIWKETHRKEHSKDNTHNYAFSFLTYERK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN62</accession>
    <name>A0A5C6ZN62_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2892 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021309">
        <property type="entry name" value="DUF2892"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11127">
        <property type="entry name" value="DUF2892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="5"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="69" mass="7747" checksum="B35BFA413CA68D79" modified="2019-11-13" version="1">MLNTYFRVIVGTMVLLSVVLTVYVNPNWIWLTVFIGVNLIQSAFTKWCLLESILLKLGIKKGGNSCSIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNH3</accession>
    <name>A0A5C6ZNH3_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Lipoprotein signal peptidase</fullName>
            <ecNumber evidence="6">3.4.23.36</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Prolipoprotein signal peptidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Signal peptidase II</fullName>
            <shortName evidence="6">SPase II</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">lspA</name>
        <name evidence="9" type="ORF">ESY86_02580</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">This protein specifically catalyzes the removal of signal peptides from prolipoproteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>Release of signal peptides from bacterial membrane prolipoproteins. Hydrolyzes -Xaa-Yaa-Zaa-|-(S,diacylglyceryl)Cys-, in which Xaa is hydrophobic (preferably Leu), and Yaa (Ala or Ser) and Zaa (Gly or Ala) have small, neutral side chains.</text>
            <dbReference type="EC" id="3.4.23.36"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Protein modification; lipoprotein biosynthesis (signal peptide cleavage).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 8">Belongs to the peptidase A8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.23.36" evidence="6"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00665"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00161">
        <property type="entry name" value="LspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001872">
        <property type="entry name" value="Peptidase_A8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33695">
        <property type="entry name" value="PTHR33695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01252">
        <property type="entry name" value="Peptidase_A8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00781">
        <property type="entry name" value="LIPOSIGPTASE"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00077">
        <property type="entry name" value="lspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00855">
        <property type="entry name" value="SPASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 7" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="2 6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 7" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="122"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD90864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="165" mass="18270" checksum="8E75040B02F8541E" modified="2019-11-13" version="1">MKLSRTLRIVLLIVFNIAIDQISKFMVRASIDPGERIKVVGDTFLMMNVENEGAFLGMGSDMNPTLKLLFLLILPIAVLSYLLYYILSNKALDKVSVFALSCIAGGGIANIYDRIVYGSVTDFFYLDFGGVFHTGIFNVADMSVTFGMIVLFYSSFFLNKNASKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNV5</accession>
    <name>A0A5C6ZNV5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4294 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03265</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025636">
        <property type="entry name" value="DUF4294"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14127">
        <property type="entry name" value="DUF4294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023134091" evidence="1">
        <location>
            <begin position="18"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="229" mass="27136" checksum="548E8016EE7F405E" modified="2019-11-13" version="1">MKAILYILLILPMLVVAQVDPEAQDSTMVQYIYVEGDSIPKTAIDLSEVLVLSKLDFNSKDERIRYLILRRKTLKVYPYAKLAADRLTTLNERLERLDKNYEKRRYAKKIQKYIEDEFSAELKKLTKTEGQILVKLIHRQTGNTTFDLIKELRSGWRAFWFNTTANLFDISLKEEFDPMLVEEDFLIEDILERAFQQRLLERQKPAVKFDFYDLSDKWRHNTAATKTKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPE1</accession>
    <name>A0A5C6ZPE1_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">CRISPR-associated endonuclease Cas1</fullName>
            <ecNumber evidence="8">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 9" type="primary">cas1</name>
        <name evidence="9" type="ORF">ESY86_02645</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer, forms a heterotetramer with a Cas2 homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the CRISPR-associated endonuclease Cas1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="8"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004520">
        <property type="term" value="F:endodeoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043571">
        <property type="term" value="P:maintenance of CRISPR repeat elements"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.100.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01470">
        <property type="entry name" value="Cas1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002729">
        <property type="entry name" value="CRISPR-assoc_Cas1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042206">
        <property type="entry name" value="CRISPR-assoc_Cas1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042211">
        <property type="entry name" value="CRISPR-assoc_Cas1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019855">
        <property type="entry name" value="CRISPR-assoc_Cas1_NMENI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01867">
        <property type="entry name" value="Cas_Cas1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00287">
        <property type="entry name" value="cas1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03639">
        <property type="entry name" value="cas1_NMENI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="7 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 8 9" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="2 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 8" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="8">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD90876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="294" mass="33884" checksum="0DE3A0F3794BF03B" modified="2019-11-13" version="1">MLKKTLFFTNKCAITTAHEQLVIIANNKERTIPIEDIGYVVIDHNEAYISMPALNKLIHNNCACIICDDKHLPNGMLLNLNSHHVQQELFKHQIEASVPLKKQLWQQTIKEKIRNQGILLEQITAKNNKFEYLESKVLSGDTTNMEAVAANFYWKSFFEIDFKRERFGNYPNNFLNYGYAILRAATARALSGSGLLNTLGIHHKSKYNAFALADDIMEPFRPAVDEIVNFIMQNYDEQELTTEIKSELLQVLTRTVYFKTEKSPLMVGLQKTASSLQQCYTGERKKIKYPKLWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPG4</accession>
    <name>A0A5C6ZPG4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SUMF1/EgtB/PvdOfamily nonheme iron enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_02820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005532">
        <property type="entry name" value="SUMF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042095">
        <property type="entry name" value="SUMF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03781">
        <property type="entry name" value="FGE-sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="SSF56436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FGE-sulfatase" evidence="1">
        <location>
            <begin position="54"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="370" mass="40974" checksum="A4B68F2095C7DF15" modified="2019-11-13" version="1">MNFKITFIIVFAIVFFCCKEQPKPAVAAQASKTAAARVPHKILKEQPKNVSTPQGMVWVAGKTFTQGAKANDAFAMSREKPAHQVTVDGFFIDITEVTNANYKAFVDATSYITIAERSIDWEDMKKNLPQGTPKPADSLLQPGSLIFNKAVSAVVNMDNYAQWWTWKIGADWKHPAGPNSHIKGKDNFPVVHIAYEDALAYCEWANRRLPTEAEWEAAAQGTARDAIFTWGDDAQKLNENANTWQGSFPVKNESLDGFEFIAPAKSYPPNSIGIYDMMGNVWELTSDLFNVNYYQSLDTNTTLINPKGAKAGFNPDNPYQPEHIIKGGSFLCHASYCASFRISARMGTAFDSGSDHTGFRTVATVAMLRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPK1</accession>
    <name>A0A5C6ZPK1_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">LETM1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_04220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011685">
        <property type="entry name" value="LETM1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07766">
        <property type="entry name" value="LETM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LETM1" evidence="1">
        <location>
            <begin position="320"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="401" mass="46198" checksum="2C40FCF401AFE026" modified="2019-11-13" version="1">MNPSTNGWIENFCSRIAKQQLPFSNFDALYDALKTYGFIYGVNVSCVAPFATKNSYYSEDELAKINLITAMYHVYAFRNRSVNDKSFSITLLEFYETLEISDFSRWDKFFIGKSQSARLERLINDRVSLEDSTHSKNFNKSFTNSLLCVDVFIFKLFLEKSSKNINLEIKSNAAYLEQIIVGTLYQSLNSRGEITIKDKAVVDMIEASKAFDDRKAPATEDLIYNIDYNISQEEKIYLLDLVCLSVRDDEFMDATEFEFLIQLANRLELKESDITNAMKCVTSFRKAHKKTILLLQQTNPISNFFDNSYRLVNKLIRRNSKRLVKELRQSKDLLALITKSTHTDLTKEEQKRMQSQLLEILKTIPSLAIFMLPGGAILLPIFAKLIPNLLPSAFDDNHIEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPQ1</accession>
    <name>A0A5C6ZPQ1_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NAD-dependent protein deacylase</fullName>
            <ecNumber evidence="3">2.3.1.286</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Regulatory protein SIR2 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cobB</name>
        <name evidence="5" type="ORF">ESY86_01685</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>H2O + N(6)-acetyl-L-lysyl-[protein] + NAD(+) = 2''-O-acetyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide</text>
            <dbReference type="Rhea" id="RHEA:43636"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:10731"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17154"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:61930"/>
            <dbReference type="ChEBI" id="CHEBI:83767"/>
            <dbReference type="EC" id="2.3.1.286"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>H2O + N(6)-succinyl-L-lysyl-[protein] + NAD(+) = 2''-O-succinyl-ADP-D-ribose + L-lysyl-[protein] + nicotinamide</text>
            <dbReference type="Rhea" id="RHEA:47668"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:11877"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17154"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:87830"/>
            <dbReference type="ChEBI" id="CHEBI:87832"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="3">2 residues (Tyr-53 and Arg-56) present in a large hydrophobic pocket are probably involved in substrate specificity. They are important for desuccinylation activity, but dispensable for deacetylation activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the sirtuin family. Class III subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.286" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034979">
        <property type="term" value="F:NAD-dependent protein deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036054">
        <property type="term" value="F:protein-malonyllysine demalonylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036055">
        <property type="term" value="F:protein-succinyllysine desuccinylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006476">
        <property type="term" value="P:protein deacetylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01412">
        <property type="entry name" value="SIRT5_Af1_CobB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01121">
        <property type="entry name" value="Sirtuin_ClassIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027546">
        <property type="entry name" value="Sirtuin_class_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="9"/>
            <end position="28"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="86"/>
            <end position="89"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="169"/>
            <end position="171"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD91321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="225" mass="24987" checksum="7E57AA79F0DFD6C3" modified="2019-11-13" version="1">MKHLVVLTGAGMSAESGLKTFRDDDGLWEGHDVMEVATPEGFAKNPELVLDFYNQRRKQLLEVLPNPAHYELAKLEDDFKVSIITQNVDDLHERAGSSHVTHLHGELLKARSSRDENDVKIWKKNIAIGDLCAKGSQMRPHVVWFGEAVPMIDVAIDICMEADMLLIIGTSMQVYPAASLMHYVPAKTPTYFIDPKPAIDSNGPLTVIKANATIGIKRFLKLIGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZA25</accession>
    <name>A0A5C6ZA25_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RagB/SusD family nutrient uptake outer membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_19535</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SusD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000042">
        <property type="protein sequence ID" value="TXD86712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033985">
        <property type="entry name" value="SusD-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012944">
        <property type="entry name" value="SusD_RagB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14322">
        <property type="entry name" value="SusD-like_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07980">
        <property type="entry name" value="SusD_RagB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="SusD-like_3" evidence="6">
        <location>
            <begin position="42"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="SusD_RagB" evidence="5">
        <location>
            <begin position="389"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD86712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="511" mass="56698" checksum="EB7ADAFC28E70C33" modified="2019-11-13" version="1">MKNTIKFLTLSVLTISFSCTDLEIEQTDSAFDETLSSEFQGVDPATSLDGIYNDLRGQIQGQEGLYALNEVSSDELLVPTRGTDWGDNGVWRNLHDHNWNPLHRDVVNTWNSLNQNVFKATLIIDPRSNSSAQQVAEAKFLRAFSTFWIADLYGQAPFRTPDEGAGINPSVKTRAEAFDFAVQDLTEALPDLLATGPSASLNRASKASANFLLAKLYLNRNVLSGTAVDAADMTKVVQYVNAIQDDGFALQSGYFDIFEDTVDSETILFTTSEVGPRIWNTLHYKQNSPDNEGGGWNGFTTLSEFYDTFEGDPNINEPGSGQEERRGYVPTDGSNLGIGYGFLIGQQYDETGTAMTDRVGNPLDFTRELPGLLGNDEVTGIRVIKYHPENGGFTGHQIVFRYADAHLMKAEAILRGATSSETALSLVNELRAMRNLNGNTTPLTAVSEQNMLDERGRELYGEFWRRNDQIRFGKFSEPWQYKSNTDAYRVLFPIPATAIISNPNLVQNEGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAG6</accession>
    <name>A0A5C6ZAG6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19755</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000047">
        <property type="protein sequence ID" value="TXD86606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="90" mass="10754" checksum="41E058EAC8ED86CD" modified="2019-11-13" version="1">MKKILTILICFSFNFIIGQGIEIIKINKYQCAIFSKQYKLPNSELPVEKRFTPNVEEIKLFENQLYSEFKEFNKNNPNQIKSKSRLYLRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAT7</accession>
    <name>A0A5C6ZAT7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000046">
        <property type="protein sequence ID" value="TXD86624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011652">
        <property type="entry name" value="MORN_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07661">
        <property type="entry name" value="MORN_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022701633" evidence="1">
        <location>
            <begin position="23"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="447" mass="51304" checksum="8A05BF523F43C0A2" modified="2019-11-13" version="1">MTSNIRPFIFLFLLVFTISAEAQIQTALPISKESETDIRSYSGIISEQYANGSPSLWKTLKNGKAEGLWLEWYLDGTLRYRANWKNSMGEGKWEYFHPNGKLRSESFYMEDRAFGISRSYYENGQLQSDVTYANDEKVGVEYVYKTDGTLQDRRRYENGIEVIDQAQLFEQGKISTNQNNEWGINFTPDGNTAYFTRRDVTTNQKRIYVTTKNEKGWSEPKIAPFSASEDESAFINSQGTKLFFASCRPLLNNNSSKNTDMNIWVMNKQGNEWSIPQPLSDTINKLMKADNVWPENYEAGPITDKEGNLYYWTKGAYSKATNLFYAELKSDGTFEKPTELIEPSDNTFFDSAPCLSSDGNLLFFASDNRPNSWGTDLFYSKKVNGKWSKPKNMSIAINSYSDDSFPSFSPDGKYFFFSSNRAGNKDTSGELTWDLYYIETRFLMLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAX9</accession>
    <name>A0A5C6ZAX9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20355</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000067">
        <property type="protein sequence ID" value="TXD86359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="128" mass="14775" checksum="EFC53CA75B4E2763" modified="2019-11-13" version="1">MKIRYKKKRLNYYLIFGVLWTVLGSLSIISHSNIILNYGSLILGVLFFGKYYFMTNRQYLTIENGIISKNQLIPKKINLNEVKVIKKLSGDYILQTDSAELEIDTELIEENSLSVLNALLKNLNLETK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAY3</accession>
    <name>A0A5C6ZAY3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_20020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000054">
        <property type="protein sequence ID" value="TXD86519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="178" mass="20389" checksum="550BD17929F9CF03" modified="2019-11-13" version="1">MKHKTKLLIIGFLILISCSEKSEFLEDCECEKIDLKNGIVVNGKENRYSVVLPDSSWNPEITDIGLSAGTFDDSSFKYFGINEMGKAKPWMSLDEQQKDVERKYDVIESGVSDMLQKKSIWNLVEEKFNTIPIIGLYVTVEHPTDDLFYTVNLAVSKNKYGKKELCELENIIKSFKMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBF5</accession>
    <name>A0A5C6ZBF5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">IS1182 family transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19780</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000047">
        <property type="protein sequence ID" value="TXD86611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="52" mass="6170" checksum="5AE2FB44C720312C" modified="2019-11-13" version="1" fragment="single">MKYISGKDRKQTCLFPVSLEDSIDQFNSVRAIDQFVEQLDLEKLGFRRDFIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBL8</accession>
    <name>A0A5C6ZBL8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF2971 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_17730</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000028">
        <property type="protein sequence ID" value="TXD87156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021352">
        <property type="entry name" value="DUF2971"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11185">
        <property type="entry name" value="DUF2971"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="307" mass="36553" checksum="99AD89E65394399B" modified="2019-11-13" version="1">MSKNWKNKYLKFISAENFEEAIPLKTNNFPNSFFKFRHLSLRTIESIKDNYIWLAEISSLNDPFECSVQIDNNECLRQYHSTDGFKKMFKFLSGHELTEKEVKLLTTSTKPHETYVDICKNHKLPFSLTPEQHLDKVNERWNQIVKDINLELRICSFSTTKKSLLLWSHYADEHKGISIEYDFVDTELVTTFIQPVIYRDLIEKLGFFDEYSVMKMVGSSLIKSKDWKYEKEWRLTIFKQKENFPQKVNVPKPIAIYLGSRFDLNEEKLKIELFKIAVEREIPIFKMIKHPNEFKLIADKTQLLSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBQ3</accession>
    <name>A0A5C6ZBQ3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Tetracycline regulation of excision, RteC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_17940</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000028">
        <property type="protein sequence ID" value="TXD87196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018534">
        <property type="entry name" value="Tet_reg_excision_RteC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09357">
        <property type="entry name" value="RteC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="279" mass="33097" checksum="A9D531FAF01B59DC" modified="2019-11-13" version="1">MKYQELILEFETNLEILESQSDDVLYKAESGISKTEKCIKKLRRRVIEKGFNSKGEEISFFKHVKPQIFSRLIYYVRLFNIESKRPRSSSKFQIKYLNNHINKLQVFFNENLDFYHYYRMGATTLDEEYFVRGKSYLRLPTQSYHFIIDEQFSTYQDATVATIIAYDMLIVYLQQEIEKLQTNTETINNNMKYATSKLFWTGSKTQLIELIYALHSSGAINSGTADIKELASMFEQLFNIELGNYYHTFIEIRARKRSKTKFLDNLTESLNKRFKDSDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC73</accession>
    <name>A0A5C6ZC73_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_18575</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000032">
        <property type="protein sequence ID" value="TXD86996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="105" mass="11670" checksum="F40F780C4CE01CF8" modified="2019-11-13" version="1">MELNSGNIKIKIAIALNRLLTINIEYSKVEDDDLDIIKSYNKIALDADIRKATVSDAFNAKSKSGPNSTTIVLIIEAMGFSIKDFAIIYDSINKNDIENFNNSKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC87</accession>
    <name>A0A5C6ZC87_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_17975</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000029">
        <property type="protein sequence ID" value="TXD87117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="129" mass="15062" checksum="6C3D719FBF4E548B" modified="2019-11-13" version="1">MPYQDEFVLFWDQVRESIHDRRFAKLTMAKTIGKPDLKNIFVRPIYSEDGFKVLVKLRYASKETEDEEKELTLEDAFEFLKSHLKTPFSTVLLFTTTKDVTFKINKKGAGTITENVPTFRDVTQAKTDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCB8</accession>
    <name>A0A5C6ZCB8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein GrpE</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">HSP-70 cofactor</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">grpE</name>
        <name evidence="6" type="ORF">ESY86_17520</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the GrpE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000027">
        <property type="protein sequence ID" value="TXD87234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000774">
        <property type="term" value="F:adenyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00446">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.22.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01151">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000740">
        <property type="entry name" value="GrpE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013805">
        <property type="entry name" value="GrpE_coiled_coil"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009012">
        <property type="entry name" value="GrpE_head"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21237">
        <property type="entry name" value="PTHR21237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01025">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00773">
        <property type="entry name" value="GRPEPROTEIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51064">
        <property type="entry name" value="SSF51064"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58014">
        <property type="entry name" value="SSF58014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD87234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="180" mass="20725" checksum="2547C3737771459F" modified="2019-11-13" version="1">MSTKDNEETLEESQLQEETNTADTTEQDELTTEEQLHADLAKEKDKFMRLFAEFENYKKRTSKERMDFFKTASQDTMTALLPILDDFERAMLHSQDDKEAEAMRQGVLLIYNKLVNTLNQKGMELIQVEAGDVFDADMHEAITQVEAPSDDLKGKIVEVVEKGYKLGERIIRFPKVVIGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCF5</accession>
    <name>A0A5C6ZCF5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000030">
        <property type="protein sequence ID" value="TXD87086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="3"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="277" mass="31502" checksum="033FF1156A4A3372" modified="2019-11-13" version="1">MTWGTWGKQLKKTEMIALMQYYLEHGINTFDHADIYGGYTTEEDFGSAFAESGLKREQIQLISKCGIQEISENRDNTVKHYDYSKDHVIWSAEKSLKHLKTDYLDVFLLHRPSPLMQPAEIAEAITHLKAQGKIKAFGVSNFTPSQTELLAQNTDIDTNQIECSLSQHSAMHDGSLDHMMVNKIQPMAWSPLGTVFKEDNAQSKRIHEQLEVLQEKYSATKDQLLLAWILKHPAKINPVIGTTNKKRIENAVNALDINLELEDWFKLLVASQGHKVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCG0</accession>
    <name>A0A5C6ZCG0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phospholipase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_16115</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000021">
        <property type="protein sequence ID" value="TXD87690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003140">
        <property type="entry name" value="PLipase/COase/thioEstase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02230">
        <property type="entry name" value="Abhydrolase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Abhydrolase_2" evidence="1">
        <location>
            <begin position="37"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="247" mass="27239" checksum="BB1B1BF42E5084A3" modified="2019-11-13" version="1">MLQGLAQDLSLFSKEQFIQNNDSLLYRMMLPKDFDASKTYPLVLFLHGAGERGNDNESQLTHGAALFASEDTREQFPAIVVFPQCPKGDYWANAEVDRSTKPITLLFPKDLKPTKSMVLAMNLLDQMLENEYVDKNQIYVGGLSMGAMGTFEMLSHKPETFAAAFAICGAGNAEATASYAKNTALWVFHGAHDDVVNPLASVEMVAGLLKNGGKPNFSLYAEDNHNSWDSAFAEPDLLPWLFSNSKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCL1</accession>
    <name>A0A5C6ZCL1_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sec-independent protein translocase protein TatC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 6" type="primary">tatC</name>
        <name evidence="6" type="ORF">ESY86_19375</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Forms a complex with TatA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TatC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000039">
        <property type="protein sequence ID" value="TXD86769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033281">
        <property type="term" value="C:TAT protein transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043953">
        <property type="term" value="P:protein transport by the Tat complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00902">
        <property type="entry name" value="TatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002033">
        <property type="entry name" value="TatC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30371">
        <property type="entry name" value="PTHR30371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00902">
        <property type="entry name" value="TatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01840">
        <property type="entry name" value="TATCFAMILY"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00945">
        <property type="entry name" value="tatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0811">Translocation</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="97"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="188"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="221"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="242"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD86769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="279" mass="31610" checksum="1ED574C294384C3D" modified="2019-11-13" version="1">MAKTKPDEMSFLDHLEDLRWHLVRVVIAIVIGGAVAFMFSDFIFNVIIFGPKSMDFPTYKYLCEISKFVGLDTSFCADKLPFSIQNRTMGGQFSADIWTAIYSGFIISFPYVIYQFWHFISPGMHPDERKHSKGFIAISSLLFFLGVLFGYYVVTPLSINFLGTYSVSDIISNEIDISSYISLVRSSAIASGFIFELPIIIYFLTKVGIVTPEMMKKYRKFALVIVLILSAVITPPDIASQIIVAIPILILYQVSIYISKVVIRNQKRKEKNDAKKKVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCM2</accession>
    <name>A0A5C6ZCM2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15895</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022660546" evidence="1">
        <location>
            <begin position="19"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="145" mass="16645" checksum="810A34B3324EC89F" modified="2019-11-13" version="1">MKIAVTIALMLSSFIIDAQSYIRQGKGDYNEVLYTWDGKYLRQGKGNYNTVLATYDGNYFRQGKGDYNSVLSTWDGKYLRLGKGDYNDVLFTWDGEYIRQGKGDYNTVLYTFDGKYLRQGKGKYNTVLYTITGDIPIAVLIFIVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCM7</accession>
    <name>A0A5C6ZCM7_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Oxoglutarate dehydrogenase (succinyl-transferring)</fullName>
            <ecNumber evidence="2">1.2.4.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_19250</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.4.2" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000038">
        <property type="protein sequence ID" value="TXD86792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004591">
        <property type="term" value="F:oxoglutarate dehydrogenase (succinyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032106">
        <property type="entry name" value="2-oxogl_dehyd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011603">
        <property type="entry name" value="2oxoglutarate_DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031717">
        <property type="entry name" value="KGD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042179">
        <property type="entry name" value="KGD_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23152">
        <property type="entry name" value="PTHR23152"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16078">
        <property type="entry name" value="2-oxogl_dehyd_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16870">
        <property type="entry name" value="OxoGdeHyase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000157">
        <property type="entry name" value="Oxoglu_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00239">
        <property type="entry name" value="2oxo_dh_E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="Transket_pyr" evidence="6">
        <location>
            <begin position="579"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="471"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD86792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="922" mass="105854" checksum="1080ACFC64C7F36B" modified="2019-11-13" version="1">MDKYSFLNAAHTAYFAELYDQYLKNPDSVEPSWRAFFQGFDFGSESGSEMVEDIPTEAFSCDDVSEGITKEFQVLKLINGYRNRGHLFTRTNPVRERRQYSPTLDIQNFGLSESDLETEFSAGDILGIGKQSLKEIIRHLKSIYCDAIGVEYMYIRNPDEIEWIQKKLNVNDFQPDFSSDEKKHILKKLNEAVAFESFLHTKYVGQKRFSLEGNETLIPALDSLIENAANHGVKEFVMGMAHRGRLSTLTNIFGKSAKDIFSEFDGKDYEQKIFDGDVKYHLGWTSNRKTQAGHEINLNIAPNPSHLEAVGAVVEGITRAKQDDKYADDPSKVLPIIVHGDAAIAGQGIVYEIIQMSNLEGYKTNGTIHIVVNNQIGFTTNYLDGRSSTYCTDVAKVTLSPVLHVNADDAEAVVHAMLFALHFRMKFKRDVFIDLLGYRKYGHNEGDEPRFTQPKLYRAISNHKNPRDIYAEQLISEKVIDEDHVDKLEKEYKDKLEENLEDSRKIDKTVITPFMQGEWENYNNVTEDQMITKIDTTYSKEGLEKIAKVISNLPEDKKFIKKIERLVQSRQTMFDEDKLDWSMAEHLAYGTLLEEGYDVRMSGQDIERGTFSHRHAVIKVEDSEEEIVLLNEISDKQGRFFIYNSLLSEYGVVGFDYGYAMASPKTLTIWEAQFGDFSNGAQIMMDQYISAAEDKWKLQNGLVMLLPHGYEGQGAEHSSARMERYLQMCAKDNMFVMDCTTPANMYHLLRKQMKGNFRKPLIVFTPKSLLRHSMVVSTVDEFANGSFQMVIDDANVKVKEVKSLIFVTGKFYYDLYEAREELKRKDVALVRVEQLFPLPEKQIKEMIKKYNKAEEVVWAQEEPRNMGAYSYLLMHLDEAKTFRVASRRPYGAPAAGSSVRSKKRHQQVIDFVFDKEKDNQRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCS1</accession>
    <name>A0A5C6ZCS1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DsbA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_20215</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000060">
        <property type="protein sequence ID" value="TXD86441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="210" mass="23383" checksum="67CA0EC139A81E0C" modified="2019-11-13" version="1">MKIVYVYDALCGWCYGFSPVITQFQEKYKDSLSFEVISGGMITGGRIGPIGEVASYISWAYKGVEKATGVKFGSEFLNKTLKNGDAIFTSVPTAIALSVFKNLDPNNNIRFASALQRAIYYDGIEPENLDAYGQIALKFGLDAKSFVLKMKDPLYKKLAEDDFKKSAELNVSGYPTIFIKINGTYQKIGSGYIPFSELKSNYLSIKKRMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCU9</accession>
    <name>A0A5C6ZCU9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">S41 family peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_18820</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the peptidase S41A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000034">
        <property type="protein sequence ID" value="TXD86923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07560">
        <property type="entry name" value="Peptidase_S41_CPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004447">
        <property type="entry name" value="Peptidase_S41A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00245">
        <property type="entry name" value="TSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00225">
        <property type="entry name" value="prc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="PDZ" evidence="4">
        <location>
            <begin position="86"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD86923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="543" mass="60663" checksum="67FD22296887AC3A" modified="2019-11-13" version="1">MKPKTKYIPLLLGLAVALGIVIGGKLNFTDTSDRLFTTNSKKDKLNRLIDYIDYEYVDDVNTDSIVDVTVNGILDNLDPHSTYIPKSDLERVTNNMKGDFVGIGVNFYTYNDTVTVIRPLAGGPSEKAGIKGGDRIIMADGDSIFGKDWSNDDIIHKLQGEKGSRVALTVKRKGIAKLLKFNVKRDVIPIKSVDASYMLTKDLGYIKINRFAESTYKEFKRALNALQAQGATKLALDLRDNPGGFLAIAEQIADEFLENGKLILFTKNKSGKVENSYATKRGDFEEGEVYIMINESSASASEIVAGALQDNDKGTIVGRRSYGKGLVQREMALGDGSAIRLTVSRYYTPTGRSIQRPYDKGNSEAYYKDYFKRLSSGELDHPESVIYADSLKYTTPKGKVVYGGGGIIPDVFVPLNTSMQNETLNYINRLGYIGNFVFGELDKDRSIYEGITPEEFIQSFYISDDIILKFQEYLNFKEDTNLTFVAYHDQIKRMIKAALAEQLFGSDVAAKIFNEDDEMIEEVIMLSQGKTLFDYEKETVKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCZ3</accession>
    <name>A0A5C6ZCZ3_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8">30S ribosomal protein S3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 13" type="primary">rpsC</name>
        <name evidence="13" type="ORF">ESY86_14860</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 10">Belongs to the universal ribosomal protein uS3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.32">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01309_B">
        <property type="entry name" value="Ribosomal_S3_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004044">
        <property type="entry name" value="KH_dom_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005704">
        <property type="entry name" value="Ribosomal_S3_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001351">
        <property type="entry name" value="Ribosomal_S3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036419">
        <property type="entry name" value="Ribosomal_S3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018280">
        <property type="entry name" value="Ribosomal_S3_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07650">
        <property type="entry name" value="KH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00189">
        <property type="entry name" value="Ribosomal_S3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54821">
        <property type="entry name" value="SSF54821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01009">
        <property type="entry name" value="rpsC_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50823">
        <property type="entry name" value="KH_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00548">
        <property type="entry name" value="RIBOSOMAL_S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 8 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 8 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 8" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="KH type-2" evidence="12">
        <location>
            <begin position="38"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="217"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TXD87947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="241" mass="26936" checksum="8072A16D575705B0" modified="2019-11-13" version="1">MGQKTNPIGNRLGIIRGWESNWYGGNDYGDKLAEDDKIRKYIHARLFKASVSRVIIERTLKLVTVTITTARPGIIIGKGGQEVDKLKEELKKITDKEVQLNIFEIKRPELDAFLVGSSVARQIENRISYRRAIKMAIAAAMRMNAEGIKIQISGRLNGAEMARNEHYKEGRIPLSTFRADIDYALVEAHTTYGRLGVKVWIMKGEVYGKRDLSPLVGLSKKQGGKTAGGGRGGNTKPRRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDF8</accession>
    <name>A0A5C6ZDF8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TolC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_19170</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000037">
        <property type="protein sequence ID" value="TXD86815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022837494" evidence="2">
        <location>
            <begin position="23"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="470" mass="53689" checksum="D18D6E6838219FDF" modified="2019-11-13" version="1">MTICRQILCCIMAFAFANLVTAQESFEVLTFEEYLGYVKEHHPLMKQANLTLSIGEANLLRARGGFDPKIEVDYDRKKFKTTEYYDRLNATFKIPTWYGIEFKGNFEENSGQFLDPSFTVPEDGLYSAGVSFSLAQGFLINERMAALKQARFFEQQSQADRDLLVNNLLFEASQAYFEWLQATQEQQIYLNFLENAEFRLNAVVRSVEEGAIAAIDITEARITLQSRKLDLEAATLKRRKAELNASNYLWLNDIPLTIEENVIPVLPSVDLLQTILILDGITNVEGLSPNHPKLQSLQAKIDGLLVEQRLKKNKLLPKIDLQYNFLSQDYDQFNSFNTTNYKAFVNVSFPIFLRKERGDLQLTNYKIDDAQFDQKAVILSLANKIRATNAEIASLNTQNQLIIDIVSDHETLVAAEERKFFVGESSLFLINTREQKLIDAQLKENELLIKQLNATALLYNILGKSEIRSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDK3</accession>
    <name>A0A5C6ZDK3_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UnbV_ASPIC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_19545</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000042">
        <property type="protein sequence ID" value="TXD86714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.130">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013517">
        <property type="entry name" value="FG-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011519">
        <property type="entry name" value="UnbV_ASPIC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13517">
        <property type="entry name" value="FG-GAP_3"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07593">
        <property type="entry name" value="UnbV_ASPIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="SSF69318"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="UnbV_ASPIC" evidence="2">
        <location>
            <begin position="526"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1088" mass="121629" checksum="A341287747E72CB1" modified="2019-11-13" version="1">MRFQKFSKSINKIVAIASLVSLFGCGQEEPPVFTKVNMATSHIDFTNTLTETKDLSILDYLYFYNGGGVAIGDINGDGLADIFFSGNQVKNKLYLNKGGMQFEDISKQAGIEGNSSWNTGVAMGDVNGDGLLDIYVCAVVGVNGFYGHNELFINNGDDTFKESASEYGLDFDTFSSSVAFLDYDLDGDLDMYLLNHAVHTQESFGKADLRHQRNYQSGDRLMRNDNGKFIDVSEEAGIFGGPNGYGLGLAVADFNQDGYPDIYVGNDFHEDDYYYLNNGDGTFTDHMRTYFGHTSKFSMGNDVADINHDGLQDILTLDMNAEDEMVLKASEGDEDIQIQKLRTDQYGYYYQFMRNMMQVNQPDGSFQETALLSGVASTDWSWSALFGDYNQDGEQDLFISNGIERRPNDLDYINYVSNDQILNKINNTNLVDQEALLKMPSGKVPNYIFMGKGNLRFENKSKTWFDDNPPSVSNASAVGDLDNDGDLDLVVSNLNELVSIYENQTDKTANGYLKIRFNYEAPNTFGIGTKVYAYTNGELQFKELYTTRGFQSTSEPVIHFGFAEAKRIDSVKVIWPNKTFQVLKDVKLNQTLVIRPENTKPLKQNVVLKNKMFEKVEGNLGIDFIHEEDNNLDFLRQKLIPYKISDKGPAVAVGDLNGDGKEDIFFGGSKFKTAKVYLQTDSSYIEATFPVSTKDSIKEDVSALIADLNNDKKNDVFIATGGGDFYDKMKPLQNSYYTQNKDAGFTVQQLPHNFENASVVKACDFDNDGDLDLFVGGYAVTNDFGKIPNSYILVNTNGAFSIADGAYQMGMVTDAVWDDFDGDGFKDLIVVGEWMSPKFYKNTNGKFIETTKISNLNGLWQAIEPFDIDADGDTDYLLGNWGMNTKFTASEDYPMLMYYSDFDGNGQTETIVCTAKDDIYYPILGLDELSSQLVFLKKKFNSYKSFAGQPITSVLDQKMIENANTLQVHTLQSGYLENDKGHFKFVPFMNELQVAPITSFLKYDFDGDNKEEVFASGNYLGVTPFHGRLDAFSGALIKNSKSISVATQLGMNLSNKAVKKINIIHFKDKPYLLVTFNNSKAEVYSILK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDK8</accession>
    <name>A0A5C6ZDK8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Energy transducer TonB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_14475</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037682">
        <property type="entry name" value="TonB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03544">
        <property type="entry name" value="TonB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_C" evidence="2">
        <location>
            <begin position="168"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="241" mass="26871" checksum="5C329ECD51EBF04E" modified="2019-11-13" version="1">MESKKSTKADVGRNSSLYFAVGLTLMMGLTYLTINYKTFEKEVIDIGLVDLGDLDEEEIPITQQQIIPPPPPPPPPVVPEEIEIVEDEKEIEETVIESTESTQEEEIVEVEEVEVAEIEEDIEVPFSVIENVPVFPGCENEKDNNAKRQCMSDKIASFVNKKFNTELASDLGLSGRLRINVIFKIDKTGNIIGIRARAPHPGLEKEAQRVIGLLPKMKPGKQRGKAVTVPYSLPILFQVQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDL6</accession>
    <name>A0A5C6ZDL6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">LytTR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_17825</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000028">
        <property type="protein sequence ID" value="TXD87173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007492">
        <property type="entry name" value="LytTR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04397">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00850">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="HTH LytTR-type" evidence="2">
        <location>
            <begin position="168"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="270" mass="31979" checksum="4CB45973456F8E4F" modified="2019-11-13" version="1">MVFSRSIAYTSSWYHTFILSVILATVIVIVLIFLQPFDIYANEIAHKNIKLIGYGFCNIIPILLIHFFEGFWFIRNQGKWYIHQELFILLFGFLLISLVSYFYNILIVNDLKTEPEYIFRWFKDFSLPFVPIFIPFWAYLRFRFSKTTMHPTLFESKKEVSIQGNNQNETIKFHEKDFIMARAQSNYVDVFFVKDNLLEKQMIRSTLLNIKSKIPSAAQVHRSFLVNPQQIDKISGNSRKGDITLNYLEYEVPVSPKHFLGLKKYLQNRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE24</accession>
    <name>A0A5C6ZE24_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Ribonuclease Z</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_17145</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000025">
        <property type="protein sequence ID" value="TXD87395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="110" mass="12656" checksum="29E849946AC9E000" modified="2019-11-13" version="1">MIIDKDGNTTLITQEKASIVELVKKIDVLYERFKNDNIIVNLMSLDKVTLQDVVEFLQLSNKHRRAKHSFVIVSNSFNLGETPDEIIVVPTTKEAFDVIEMEEMERDLGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE33</accession>
    <name>A0A5C6ZE33_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">T9SS type A sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_17020</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000025">
        <property type="protein sequence ID" value="TXD87373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000923">
        <property type="entry name" value="BlueCu_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00127">
        <property type="entry name" value="Copper-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022971504" evidence="1">
        <location>
            <begin position="19"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="Copper-bind" evidence="2">
        <location>
            <begin position="37"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="Por_Secre_tail" evidence="3">
        <location>
            <begin position="128"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD87373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="203" mass="22309" checksum="9B7315B26F850A0C" modified="2019-11-13" version="1">MKVKLLFIFFITVFAATAQTTETYDLDWFTGIGNDVDLTIETGDTVTWTWTSPNHTVENNPNGTSEETFDSGLLQPNGSVFSYTFTLLGSNDYYCGIHGANSMSGTITVLAEGTLSSVQFEKPIAFSIYPNPSVESMKISLPSLIDGGLNLAVFDILGKQIYSKSLNELNSNINISKWNAGIYLVRISSSDESISLVKRFVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE65</accession>
    <name>A0A5C6ZE65_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase family 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_16875</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000024">
        <property type="protein sequence ID" value="TXD87452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="17"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="342" mass="39415" checksum="4BEA8B8F6DEDA721" modified="2019-11-13" version="1">MELNNNKATLTLEDGVSIVVVSYNGAERLIPTLKHLANQESIGFCVEVILVDNCSTDNTREIAKSFWHELGIPFPLRIVQETQAGTMFARKKGIEVSSYRYLLYCDDDNWLCKHYLSTAYNIISKDPNIAALGGCGYMQYEHNFMPPNWIKDYEKNYGTGPQGREDGDTTFSKGCLYTAGTILDKAWLDKLYAKGFASALEGRIGDTLIAGEDTELTYALKLIGGKLYYSSKMTFQHFMPKKRITWGYLKRLWFSFGYSNYIISPYNEFYQKRKQLNKVHYLIKRIKEIVKLSLIITKHQLSEGQKPVLERRWKLGEIKAMIYSSKKYQKVQKTIQKLQIDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE80</accession>
    <name>A0A5C6ZE80_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_18225</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000030">
        <property type="protein sequence ID" value="TXD87070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="78" mass="9266" checksum="91AF78C5221CE077" modified="2019-11-13" version="1">MDLRADLDWIHNELEKVDDPQVVCKIQKLLKSKYLPEGNRESIQQYNDELDASIAQITNKKTFSHHEMGERIKRWAEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEF2</accession>
    <name>A0A5C6ZEF2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_13900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="128" mass="15136" checksum="19FBDC2C430C8549" modified="2019-11-13" version="1">MSISWDKIVKIPRWGPYDVVGVIFFAAFVISTSFFYFNEWQFNAEDWKRAPSKRHEMVDDLLDSEILVEKSKEEVLMLLGEPYSDIDKNRDIFRYRLGTPPSFFKPEREQLFIVFEKNMVVSVALANE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEK9</accession>
    <name>A0A5C6ZEK9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipid-binding SYLF domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_16420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023067020" evidence="1">
        <location>
            <begin position="22"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="176" mass="18291" checksum="3F7F2980AA5E25E0" modified="2019-11-13" version="1">MKTLKTILALGILFISFGAMAQNDDDKRIMADAENAKTTMMAADASLGDFFNNSAGYVIFPNVGKGGFIIGAAAGNGVLYENGTAQGMAKLKKLSVGLQAGGQAISEIIFFENEAALNSFKDGDFEFAAGISAVVLKTGKAETAQYKEGVAVFALPKAGLMAEASVGGQKFSYDSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEM5</accession>
    <name>A0A5C6ZEM5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">tRNA-dihydrouridine synthase</fullName>
            <ecNumber evidence="10">1.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">dusB</name>
        <name evidence="13" type="ORF">ESY86_12920</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 10">Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a 5,6-dihydrouridine in tRNA + NAD(+) = a uridine in tRNA + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:54452"/>
            <dbReference type="Rhea" id="RHEA-COMP:13339"/>
            <dbReference type="Rhea" id="RHEA-COMP:13887"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 5,6-dihydrouridine in tRNA + NADP(+) = a uridine in tRNA + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:23624"/>
            <dbReference type="Rhea" id="RHEA-COMP:13339"/>
            <dbReference type="Rhea" id="RHEA-COMP:13887"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 10">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the dus family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.-" evidence="10"/>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017150">
        <property type="term" value="F:tRNA dihydrouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001269">
        <property type="entry name" value="DUS_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024036">
        <property type="entry name" value="tRNA-dHydroUridine_Synthase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004652">
        <property type="entry name" value="tRNA_dU_NifR3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006621">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00737">
        <property type="entry name" value="nifR3_yhdG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 10" id="KW-0288">FMN</keyword>
    <keyword evidence="9 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7 10" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Dus" evidence="12">
        <location>
            <begin position="16"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="11">
        <location>
            <position position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00002790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR006621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR006621-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TXD88415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="330" mass="37206" checksum="876B2125AFA5CD5C" modified="2019-11-13" version="1">MIKIGDIELKDFPLLLAPMEDVSDPPFRALCKEQGADVVYTEFISSEGLIRDAAKSVMKLDIYEKERPVGIQIFGANMESMLQTIDIVEKSNPDIIDINFGCPVKKVVSKGAGAGILKDVCLMERLTAEMVKRTNLPVTVKTRLGWDHDSIKILEVAERLQDVGCKAISIHGRTRAQMYKGEADWKPIAEVKNNPRMHIPVFGNGDVDTPEKAMLMRDGFGLDGCMIGRASIGNPWFFKQVKHYFKTGEHLGPISMAERVDAARRHLEMSIAWKGEKLGVFETRRHYTNYFKGIPDFKTYRMKMVTSDDPEAVFAAFDEVLEVFGDYQFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEQ5</accession>
    <name>A0A5C6ZEQ5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphopantetheine adenylyltransferase</fullName>
            <ecNumber evidence="6">2.7.7.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Dephospho-CoA pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Pantetheine-phosphate adenylyltransferase</fullName>
            <shortName evidence="6">PPAT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">coaD</name>
        <name evidence="8" type="ORF">ESY86_12290</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>(R)-4'-phosphopantetheine + ATP + H(+) = 3'-dephospho-CoA + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:19801"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57328"/>
            <dbReference type="ChEBI" id="CHEBI:61723"/>
            <dbReference type="EC" id="2.7.7.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 4/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the bacterial CoaD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.3" evidence="6"/>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00241">
        <property type="reaction ID" value="UER00355"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004595">
        <property type="term" value="F:pantetheine-phosphate adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02163">
        <property type="entry name" value="PPAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00151">
        <property type="entry name" value="PPAT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001980">
        <property type="entry name" value="PPAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21342:SF1">
        <property type="entry name" value="PTHR21342:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01020">
        <property type="entry name" value="LPSBIOSNTHSS"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01510">
        <property type="entry name" value="coaD_prev_kdtB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 6 8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CTP_transf_like" evidence="7">
        <location>
            <begin position="5"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="9"/>
            <end position="10"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="88"/>
            <end position="90"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="122"/>
            <end position="128"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="6">
        <location>
            <position position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00029346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD88517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="151" mass="17218" checksum="962231146ABAB5DE" modified="2019-11-13" version="1">MKRALFPGSFDPITNGHYDIIMRGIKLFDEVIIAIGVNADKKYMFTVAERLVFIEEAFKNIEKIKVVTYEGLTTDFCKKVDAQFILRGLRNPADFEFEKAIAHTNRKLSKIETVFLLTAARTSFISSSIVRDVIRNHGDYAQLVPDSVRVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEU6</accession>
    <name>A0A5C6ZEU6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Class I SAM-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_12520</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="178" mass="20923" checksum="91C1C046B9C88DF1" modified="2019-11-13" version="1">MYENTYPNKRFKHTMDFLQHYVSTEDSILDLGVTNPLSELMQAKGFEVQNTSGLDLDLDTSEIESTKANVVTAFEIFEHLLSPFTVLRSIKADKLVASIPLNLWFASAYRSKIDMRDRHFHEFEDWQFDWLLEKAGWKIIASEKWTNPTKQLGIRPILRRFTPRYYIVYAERVKNPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEV0</accession>
    <name>A0A5C6ZEV0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Sodium:proton antiporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">ESY86_15665</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the NhaD Na(+)/H(+) (TC 2.A.62) antiporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004680">
        <property type="entry name" value="Cit_transptr-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045016">
        <property type="entry name" value="NhaD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43269">
        <property type="entry name" value="PTHR43269"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03600">
        <property type="entry name" value="CitMHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0050">Antiport</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0915">Sodium</keyword>
    <keyword evidence="9" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="89"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="126"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="163"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="202"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="244"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="268"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="327"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="376"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="412"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="449"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="CitMHS" evidence="12">
        <location>
            <begin position="23"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF03600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TXD87750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="471" mass="51395" checksum="8804A3AEF75AE265" modified="2019-11-13" version="1">METIVILVFVFGYLAITVEHSIKIDKLIPALVMMAISWALIALGIDSFTQWFDSANHALVDGFASLEHEGRLEWMEETLLHHLGKTAEILVFLLGAMTIVEIIDYFDGFATIKGFIKTKSKRRILWIFGFLAFFLSAIIDNLTATIVLISILQKLVHDRNVRIWYAGLIIIAANAGGAWSPIGDVTTTMLWIGKKVTTGHLFAYLFLPSLLCMLVPFFIASFLPTFKGKLENQNEDLTRPKNKYSATMLYLGLGGIVAVPIFKSVTHLPPYVGMMLALGIVATFAEIYSNTKFSMASLTSQDSDEIPVRESHSAVHHSLSKIELPSILFFLGILMAVAALESLGILFNFAGTLQDTVPTLGTEMAAPAGEVVVSDLVILLLGLGSAVIDNVPLVAASLGMFSQGIDNALWHFIAYSAGTGGSMLIIGSAAGVVAMGMEKIDFFWYLKNISWLALIGFLSGAIAFFFTRTIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEW3</accession>
    <name>A0A5C6ZEW3_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase</fullName>
            <ecNumber evidence="6 7">6.3.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">D-alanyl-D-alanine-adding enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">murF</name>
        <name evidence="11" type="ORF">ESY86_12625</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>ATP + D-alanyl-D-alanine + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine</text>
            <dbReference type="Rhea" id="RHEA:28374"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57822"/>
            <dbReference type="ChEBI" id="CHEBI:61386"/>
            <dbReference type="ChEBI" id="CHEBI:83905"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6 7">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the MurCDEF family. MurF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.10" evidence="6 7"/>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047480">
        <property type="term" value="F:UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008766">
        <property type="term" value="F:UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02019">
        <property type="entry name" value="MurF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000713">
        <property type="entry name" value="Mur_ligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035911">
        <property type="entry name" value="MurE/MurF_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005863">
        <property type="entry name" value="UDP-N-AcMur_synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01225">
        <property type="entry name" value="Mur_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63418">
        <property type="entry name" value="SSF63418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01143">
        <property type="entry name" value="murF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6 7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1 6 7" id="KW-0132">Cell division</keyword>
    <keyword evidence="2 6 7" id="KW-0133">Cell shape</keyword>
    <keyword evidence="5 6 7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 6 7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase" evidence="8">
        <location>
            <begin position="16"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_M" evidence="10">
        <location>
            <begin position="96"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="9">
        <location>
            <begin position="293"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="97"/>
            <end position="103"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD88577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="421" mass="46783" checksum="4F41C8F80395E925" modified="2019-11-13" version="1">MTIDQIYTRFLSCSTVSTDTRTISENCMFFALKGENFNGNKFASEALKKGASFCIVDELEYAVDERYILTANVLNTLQQLATQHRKQLNTPIIALTGSNGKTTTKELINAVLSQKYNTIATKGNLNNHIGVPLTLLELTKDTEIGIVEMGANHQKEIEFLCTIALPDYGLITNFGKAHLEGFGGVEGVIKGKSELYVHLKQQHKTIFINETDTLQIKQAGDYDDIIKFGNDISLEHAPPYFNITFNTSEIKSKLTGIYNFNNICAAIAIGSHFGVPDEAIVSGIETYVPKNNRSQLIEKNNLNIILDAYNANPTSMLAALQNLQIQEHTRKIAILGDMFELGKEASQEHQAIVDFVGDLDVDSVIFVGRHFYKTNSNAAKIRFFETFEDLKSKVSELELDNALLLIKGSRGMALERVLDLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEW8</accession>
    <name>A0A5C6ZEW8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_12380</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="79" mass="8828" checksum="EA57BEBE18326E51" modified="2019-11-13" version="1">MKSTEIKTNLQSLIANFSKEGIIYDLLIAYGISKTSVTRLKKGDYNFAKVGGETKPLVNCGDDCTETEFSINRRCEFLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF29</accession>
    <name>A0A5C6ZF29_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">3-oxoacyl-[acyl-carrier-protein] synthase 3</fullName>
            <ecNumber evidence="7">2.3.1.180</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">3-oxoacyl-[acyl-carrier-protein] synthase III</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Beta-ketoacyl-ACP synthase III</fullName>
            <shortName evidence="7">KAS III</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">fabH</name>
        <name evidence="10" type="ORF">ESY86_13040</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>acetyl-CoA + H(+) + malonyl-[ACP] = 3-oxobutanoyl-[ACP] + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:12080"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9625"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78450"/>
            <dbReference type="EC" id="2.3.1.180"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the thiolase-like superfamily. FabH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.180" evidence="7"/>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033818">
        <property type="term" value="F:beta-ketoacyl-acyl-carrier-protein synthase III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01815">
        <property type="entry name" value="FabH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013751">
        <property type="entry name" value="ACP_syn_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013747">
        <property type="entry name" value="ACP_syn_III_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004655">
        <property type="entry name" value="FabH_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08545">
        <property type="entry name" value="ACP_syn_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08541">
        <property type="entry name" value="ACP_syn_III_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00747">
        <property type="entry name" value="fabH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4 7" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 7" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACP_syn_III" evidence="9">
        <location>
            <begin position="110"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="ACP_syn_III_C" evidence="8">
        <location>
            <begin position="241"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="ACP-binding" evidence="7">
        <location>
            <begin position="257"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="116"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="256"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD88437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="331" mass="36177" checksum="0096DF69B03E2C6A" modified="2019-11-13" version="1">MSHITAAITAIGAYVPEYVLTNQILETMVETNDEWITSRTGIKERRILKEDGKGTSFLAINAAQNLIDKKGLDPKEIELVIVATATPDMKAASTAAFTATEIGAVNAFSFDLEAACSSFLYGMSVAARYIESGKYKKVLLIGADKNSSMIDYTDRATCIIFGDGAGAVLFEPNEEGLGLQDELLRSDGSGRDFLQATYGGSSYPSTPEAVSQGKHYLFQEGKTVFKNAVFNMADVTERIIARNNLTNDDITWLAAHQANKRIIEATANRVALPPEKVMMNIQKYGNTTSATLPLLLSDYESQLKKNDKIIFATFGGGFTWGSIYFKWAYNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF63</accession>
    <name>A0A5C6ZF63_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15540</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010870">
        <property type="entry name" value="Porin_O/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07396">
        <property type="entry name" value="Porin_O_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023062053" evidence="1">
        <location>
            <begin position="22"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="384" mass="44147" checksum="7010EE2746D893E2" modified="2019-11-13" version="1">MIKSFFISVLLLTPLLGFSQANDSLAEPVISIDKKSLLNNINITFDMRMEFQAYTFRGGDRYYNGLQFENGFTALGISAKLHERVNFHFRNRFNKDGDVQSLDQLGSNIELAYIDVIVSPSLKIVLGKTYAFYGGYEYEFKALDVLEYNDIQSNALAFVTGAGITYQNSKNHKFGFQVLNSRTMLYEDLYGDVVAENIQEPDWPVALVGNWRGSFFDGKIQTIYSLSYSNQVKRRGTYFFTLGHKYQDHKLTLMYDFNYSFEEVDTKGIVTSILNNDAVAEDVLYIENWLRAEYRFSSKFKGLLTLMTSSAYAKVTSENNHLRRSYGMVPTLYYSPFKNIDVRFFLAYIGRYYDHTNYAIQNLGAANYNRNEVRVGFIAPLSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF97</accession>
    <name>A0A5C6ZF97_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_17110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000025">
        <property type="protein sequence ID" value="TXD87408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="370" mass="43355" checksum="B9632A84FDD45535" modified="2019-11-13" version="1">MGKAISHGNYDQAIQEALEKLDRNKDKPRKQDFIVLLEDAYYKAMQEDLQRINTLKKDSNPEYFKTIYEMYLDLDDRQLAIKRVLPLKINGKDFKLEFKDYASEIVDYRYKTSEYLLALGKSQLSSDNKYDAREAYDQFSYVEAINPNFKDTRALLQEAHLKGTDFVMVYIENQTKQIIPKQLETDVLNFDTYGLDAFWTTYHGYIDQNLSYDYDVVMRLKAISLSPERVHEKQKLNEKNIIDGWEYKKDRNGSILLDSLGNKMKIDKIINAKARYFEVSQYKSVEVIADVVFSKLGSNKPVDSFKLNSTFIFENFYAWVRGDERALSLQERELTRNRAVPFPSDQQMVFDTGEDLKLQLKNILSAYTLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFD9</accession>
    <name>A0A5C6ZFD9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Alanine:cation symporter family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_11085</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015655">
        <property type="term" value="F:alanine:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001463">
        <property type="entry name" value="Na/Ala_symport"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30330">
        <property type="entry name" value="PTHR30330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01235">
        <property type="entry name" value="Na_Ala_symp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00175">
        <property type="entry name" value="NAALASMPORT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00835">
        <property type="entry name" value="agcS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00873">
        <property type="entry name" value="NA_ALANINE_SYMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0769">Symport</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="98"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="220"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="259"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="309"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="358"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="399"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="424"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD88778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="456" mass="49086" checksum="DE6DE70B5B467A42" modified="2019-11-13" version="1">MEKLDQIVASFSSLAWGLPLLILLIGGGIYLLIRSQFIPFTLFSHALKVLRGKYDDPNDPGEISHFKALTTALSSTIGMGNIAGVALAIAVGGPGAMFWMWVSAIVGMSTKFFTCTLAVMYRGKDSNGDLQGGPMYFIVEGLGKRWKPLAVMFSAFGMLGALPVVNVNQLKQAVNDILLIPNGVEVNVYSDLLIAAILVVVTSIVILGGIKRISNIASKLVPSMVLLYFILVLIILGMNYTEVPKYLLLIVTDAFEANFIKGDAFLGGMLGALILLGIRRGAFSNEAGIGTAPMAHGAAKTKEPVREGLVAMLGPAIDTLVVCTLTALAILVTGVWQSTSDNGVTLTASAFEDAMPGIGAYALMVCVFVFSISSLFSYSYYGSKCMSFLFGTKHKHIYNYFYILSIILAATTDFRTMINLIDGVFALMAIPTMTATLIMAPRVVKEIKAYRKRFQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFF6</accession>
    <name>A0A5C6ZFF6_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">30S ribosomal protein S14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 5" type="primary">rpsN</name>
        <name evidence="5" type="ORF">ESY86_14895</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 30S ribosomal subunit. Contacts proteins S3 and S10.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.830.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00537">
        <property type="entry name" value="Ribosomal_S14_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001209">
        <property type="entry name" value="Ribosomal_S14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043140">
        <property type="entry name" value="Ribosomal_S14/S29"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023036">
        <property type="entry name" value="Ribosomal_S14_bac/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018271">
        <property type="entry name" value="Ribosomal_S14_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19836">
        <property type="entry name" value="PTHR19836"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00253">
        <property type="entry name" value="Ribosomal_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00527">
        <property type="entry name" value="RIBOSOMAL_S14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD87954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="89" mass="10239" checksum="23C0971880590ECE" modified="2019-11-13" version="1">MAKESMKAREVKREKTVAKYAEKRKALKEAGDYEGLQKLPKDASPVRLHNRCKITGRPRGYMRTFGLSRVMFREMANQGLIPGVRKASW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFP9</accession>
    <name>A0A5C6ZFP9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AAA family ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase_AAA_core" evidence="1">
        <location>
            <begin position="316"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="650" mass="74588" checksum="9A3667C927C57A18" modified="2019-11-13" version="1">MEHNSTFPIKQNELDMLRDEATSYIKSVQWEQGQRAKNKNKDNKDESILLYLNRAKGNAAEGASVSKTILDLKKRLLPDSIAIPLHLNQTLYAVQEGLTLGIWIKDSYYDASGLSSLIENKSALDTSGKREYESKMQTATAFMLFSAAYKILFDLQTSVSDDLSVMKNKFAGIPEVSLMTPLKGTSCAMFYYDKYLGHPEMIKSDQDVVDFTVVFFQALIAEIQMRKSSLEYTETIIDRTYKLEKSDFAISGWDNAFQGAAKSVEFNKIQFEQIVGNRDAKHFARRLTERLLSYDFTAQKNPFQELGGFMPVFMGYGIPGTGKSMLIAAIATRLKEHSDNLDIPFLFHPMPDTLISTFQGGSAEKMVDWMKPLQDPSKLIFAPIDDAENNLQERTAQGVSAGVKEVIGVFLRYTEGAYAVNYGNSSIGLFTNLPEMLDKAVISRVQGRFKIDGARTEHDFLDQDHLWWRKFDDTMPDFVNMKNPENYDYLQDQGLAKNMGEILNVTNKPTEERVFEVYDKMEKQYKTNEQLFYANLYKEVQKIFPFFSSRDVRNIQSAVSLRLTDFDLEQSWFDNPETYFKKDYETKFGMLQELMRANMKGLDFSEIRRQEVVRYLDNVATIADTDFKRKVESRVNQMHIDAEAREQFGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFR4</accession>
    <name>A0A5C6ZFR4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_11485</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="589" mass="65587" checksum="DF35E63C76642BA6" modified="2019-11-13" version="1">MGLAYTIDSPIRVAHYGISSVISIIDDELIEKMNAFYSKKFNLPHQEIAKKAQDHRAERITSYLNLVDSIVKDKFSRFKIELSESKSALEQFMGTLPNSSDFKAGLSNLLDEGTALKAQLKSYLETHLKAGDIDVNIMTKVDKDNFIKGEQLPVEFNDAHASLRGFANSNLNSSVVLSAGMNPRLYSYFEQFKDFFPDAAGQLKKRIILKVSDYRSATIQGKFLAKKGLWVSEYRIESGLNCGGHAFATEGFLLGPILEEFKTKKAALIQDTHEVYVKGLSLKEMAVPEQALDLKITVQGGVGTAAEHAFLLNNYQVDSVGWGTPFLLVPEATSVDRKTRELLMNAKENDLYLSGISPLGVPFNAIKGTTNEFFKQKRIDDAKPGSSCPKKFLALSKEFGPEGICTASKKYQDVKLEALEAKKSEISSDLYNNAKAKITEKACLCVGLANASYLENDIKIKGQEQGVVICPGPNLAYFDKEVSLSQMMQHINGNASVLASVNRPNMFVKELKMYVDYLRNDIRSISEDLSAKQIKKWKAFKNNLFDGIAYYQALFVTSLAAEEKAIQNELQFYKDELIAVRIPELEPVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFZ1</accession>
    <name>A0A5C6ZFZ1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">T9SS type A sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Por_Secre_tail" evidence="1">
        <location>
            <begin position="260"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="333" mass="36771" checksum="A40DA3512B505B41" modified="2019-11-13" version="1">MKRILLIIFLSIGLVFSGWSQITAAEYFIDADPGIGNATNLTISSGNQIDTNFSIPTVGLSNGLHVLHIRVKGTSNVWSLYYRDYFYILTTEAPAAGSNLSAAEYFIDTDPGVGNAIALSIASGQTIDNTFSIPTSGLANGLHVLHMRTQDLDGTWSLYYRDYFYIHSVNNFVSTPITGAEYFFDTDPGVGNGISIAITEGFTIDETLAIPVPEDMTDGNHYLYIRVKNMDDNWSTYIFALFSVDSNLSVEEINDQDFKVFPNPAHTFLNVKINSGLDYSIQLFDVNGKELIQTKTNGTLHKLDFSSYAEGLYLLHVTESKTGKRSVVKIVKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG31</accession>
    <name>A0A5C6ZG31_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">YicC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_15275</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005229">
        <property type="entry name" value="CHP00255"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013551">
        <property type="entry name" value="DUF1732"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013527">
        <property type="entry name" value="YicC-like_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30636">
        <property type="entry name" value="PTHR30636"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08340">
        <property type="entry name" value="DUF1732"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03755">
        <property type="entry name" value="YicC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00255">
        <property type="entry name" value="TIGR00255"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YicC_N" evidence="1">
        <location>
            <begin position="2"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1732" evidence="2">
        <location>
            <begin position="201"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="285" mass="33120" checksum="AD8C4EC967707619" modified="2019-11-13" version="1">MIQSMTGYGKSVLQLPSKKISIEVKSLNSKNLDLNTRMPSMYREKELAIRKLIASKLQRGKIDFSLYVEMTGEETSTQINKTVVRQYIKQLREVVDGDETELLKMAIRLPDAIMTERDDIDEDEWTEIAKVIDNSLEKIEEYRLDEGQALEQEFRARVNNISNVLEAIIAMDPERIDGVRERLNKGIADIKEKVDENRFEQELVYYIEKFDITEEKVRLKNHLDYFEKALKSEDSNGKKLAFISQEMGREINTIGSKSNHAPMQKLVVQMKDELEKIKEQLLNVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-02-10" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG34</accession>
    <name>A0A5C6ZG34_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_13805</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008503">
        <property type="entry name" value="Put_Zn_protease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05618">
        <property type="entry name" value="Zn_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="SSF50630"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn_protease" evidence="1">
        <location>
            <begin position="6"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="145" mass="17142" checksum="C863573F96F73693" modified="2019-11-13" version="1">MPKKIIGRIDKADFPTLDLFDIDIKIDTGAYTSSIHCHKFYEEDGALKCLFYDKKHPLYNGKKIVFRNFTTTKVKSSNGIVQQRYKVKTSVILFDKKYRIYLTLSDRDDMKYPILIGRKFLLKKFMVDVDLKHLSHKEKTKKLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGA7</accession>
    <name>A0A5C6ZGA7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Heme-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_10820</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005624">
        <property type="entry name" value="PduO/GlcC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038084">
        <property type="entry name" value="PduO/GlcC-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03928">
        <property type="entry name" value="Haem_degrading"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143744">
        <property type="entry name" value="SSF143744"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="132" mass="13666" checksum="E7CE0A19C1DAADC3" modified="2019-11-13" version="1">MNITLKQAQAIIEKAKAKALEIDTKMNISVVDAGANQVAFVRMDGAWLGSADIALKKAKTARFFDMPSGEIGKLAQPGGSLYNIEHSNGGLISFPGGIPLKNKDGDIIGAIGVSGSSVENDHTVAKAGTEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGB5</accession>
    <name>A0A5C6ZGB5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transketolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_10190</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016624">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transket_pyr" evidence="3">
        <location>
            <begin position="469"/>
            <end position="643"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="803" mass="89704" checksum="84E4C4B9B904B0C1" modified="2019-11-13" version="1">MSTKLKTTEDITFEDFKSEILNDYKIAVTSRECSLLGRREVLTGKAKFGIFGDGKEVPQLAWAKVFKNGDFRSGYYRDQTFMMAIDELNIEQFFAGLYGHASIDADPMSAGRQMGGHFGTHSLDENGVWKNLTEQRNSSADISPTAGQMPRLLGLAQASKIYRNVKGIDTTKFSNDGNEIAWGTIGNASTSEGLFFETINAAGVLQVPMVISIWDDDYGISVHAKHQTTKENISEILKGFQRDEHGNGYEILRVKGWDYTALVNTYETAEKIAREEHVPVLIHVQELTQPQGHSTSGSHERYKNKERLDWEAKHDCNLKMRHWMIENNIGTEEELDTLDKNIKKKVREGKKAAWDAYLDPIVKDRAEAVKLLKALANTSANKAFIDKYISDLTSIDAPIRRDILSTARKTLRYVLNETSAEKTKLQDWISAYIASLQPKYSSHLHSSSEKAALNIAGTKPTYNDNAEDVDGRIIIRDNFDAIFNTYPHAMVFGEDAGNIGDVNQGLEGLQEKYGELRVADVGIREATILGQGIGLAMRGLRPIAEIQYLDYILYALQIISDDLATLHYRTKGMQKAPLIIRTRGHRLEGIWHSGSQLGGIINLVRGVHVLVPRNMTKAAGFYNTILEGDEPAIIIECLNGYRLKEKMPNNIGRFKTPIGVVETVKEGTDITLVSYGSTLNMVTQTAKDLLQVGIDAEVIDVQSLLPLDINHDIVKSVAKTNRLMIIDEDVPGGASAYLLDAILNKQNAYRYLDSKPKTLTAKPHRPAYGTDGDYFSKPSAEDMFEAVYEVMHEVNPNDFPKLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGD9</accession>
    <name>A0A5C6ZGD9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF4249 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_11005</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025345">
        <property type="entry name" value="DUF4249"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14054">
        <property type="entry name" value="DUF4249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="270" mass="30576" checksum="9E6128B4F72D9C52" modified="2019-11-13" version="1">MKKYIAILLTLLFVSCEDVIDVDLNEAAPKLVIDASIDWYKDSMGLDQQIKLTLLTPFFNPEIAPATGAVVSITKDNNESFEFLEEGESGIYTNNTFITELNATYTLSILYDGDTYFATETLMPVVNIDYVEQNDEGGFSGEDIELKAFYTDPANEENYYFFEFITDIVEIPNLEVYEDRFTDGNQIFGFYSEEDLASGDIVTIRNHGISKRFYEYMFILLQQSSEGGGGPFETQPATVRGNCINQTNPDHFPLGYFRLSEVAELIYTVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGL4</accession>
    <name>A0A5C6ZGL4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">Biotin carboxyl carrier protein of acetyl-CoA carboxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">accB</name>
        <name evidence="7" type="ORF">ESY86_13035</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 4">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009317">
        <property type="term" value="C:acetyl-CoA carboxylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001249">
        <property type="entry name" value="AcCoA_biotinCC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001882">
        <property type="entry name" value="Biotin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01071">
        <property type="entry name" value="ACOABIOTINCC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00531">
        <property type="entry name" value="BCCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00188">
        <property type="entry name" value="BIOTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0092">Biotin</keyword>
    <keyword evidence="4" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="6">
        <location>
            <begin position="82"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="63"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD88436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="160" mass="17394" checksum="B7E37AE1005BAACA" modified="2019-11-13" version="1">MDIKEIQNLIKFVAKSGASEVKLEMDDIKITIKTGSEDKGENTTYVQQIPMNAPMAQAAPAAPTATEPTTATPTPVDENSKYITIKSPIIGTFYRKASPDKPVFVEVGTSIKEGDVLCVIEAMKLFNEIESEVSGKIVKILVDDSSPVEYDQPLFLVDPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGU4</accession>
    <name>A0A5C6ZGU4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribonuclease 3</fullName>
            <ecNumber evidence="6">3.1.26.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Ribonuclease III</fullName>
            <shortName evidence="6">RNase III</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 10" type="primary">rnc</name>
        <name evidence="10" type="ORF">ESY86_08155</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ribonuclease III family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.3" evidence="6"/>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004525">
        <property type="term" value="F:ribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00593">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00104">
        <property type="entry name" value="RNase_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014720">
        <property type="entry name" value="dsRBD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011907">
        <property type="entry name" value="RNase_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00035">
        <property type="entry name" value="dsrm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14622">
        <property type="entry name" value="Ribonucleas_3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00358">
        <property type="entry name" value="DSRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00535">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="SSF69065"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02191">
        <property type="entry name" value="RNaseIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50137">
        <property type="entry name" value="DS_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00517">
        <property type="entry name" value="RNASE_3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50142">
        <property type="entry name" value="RNASE_3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="6" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="RNase III" evidence="9">
        <location>
            <begin position="20"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="DRBM" evidence="8">
        <location>
            <begin position="173"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="66"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="134"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD89355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="247" mass="28295" checksum="FA18B693A0A570B2" modified="2019-11-13" version="1">MSFIRNILKNSRTNKDGNFFLLLNKILGYKVKNKSLYIKAFTHRSMNIKDAEGNPVNYERLEFVGDAILGAVIAHYLYEEVPHGDEGYLTKMRSKVVSREHLNELGKELKLIDLIESNIPKSNFGSNIHGNLFESLVGAIYLDKGYNFCEDFIHKIIIDPKVDIETLEGRVISYKSLLIEWCQKEKKTFDYNVYEDSGNDEVKHFSVKLSIDGKVVSKARATSKKKAEEKASKRAFFAFQKQIGKVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGY8</accession>
    <name>A0A5C6ZGY8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">DUF3817 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_10560</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023845">
        <property type="entry name" value="DUF3817_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12823">
        <property type="entry name" value="DUF3817"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03954">
        <property type="entry name" value="integ_memb_HG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="70"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3817" evidence="8">
        <location>
            <begin position="5"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD88928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="97" mass="11107" checksum="1B3F00DC259CEF72" modified="2019-11-13" version="1">MFSLLNSFRVIAFLEGVSYILLLFIAVPIKYFSDDPQYVKLLGMPHGILFLAYIVLAIMVGSELKWTKKTLFIVLLASLLPFAAFYVERKYLKPAQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH01</accession>
    <name>A0A5C6ZH01_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF1569 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_08505</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011463">
        <property type="entry name" value="DUF1569"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07606">
        <property type="entry name" value="DUF1569"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="154" mass="17681" checksum="B38084A8A5D2E566" modified="2019-11-13" version="1">MSLKKLNFALNKLENHLENQSASNPKISKSNVAWHIDHSLKVINNVSISLQTSDSSTYKNNFSFLGKVFFTIGFFPRGRARAPKHVVPPETILEEDLLTQIKKAKSNIESIEGLDKNAYFKHPFFGNINTPRIYRFLFMHTNHHVKIINDIMAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH55</accession>
    <name>A0A5C6ZH55_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CopG family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_09730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.10.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022789">
        <property type="entry name" value="ParD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038296">
        <property type="entry name" value="ParD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03693">
        <property type="entry name" value="ParD_antitoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="79" mass="9083" checksum="312294ADC6C47C1B" modified="2019-11-13" version="1">MKRQSISFTAPNDEWLKSQIDSNEYSSKSELVNDLIRQARKQQRQIDWLRVKLEKAEKSGFTNESKAQILAASKSLLNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHA2</accession>
    <name>A0A5C6ZHA2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Insulinase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_08195</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="SSF63411"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022723346" evidence="1">
        <location>
            <begin position="21"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_C" evidence="2">
        <location>
            <begin position="199"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="691" mass="76367" checksum="2454D372A5AAD758" modified="2019-11-13" version="1">MKSKISILIVIFLMSIGVSAQIDRSQPPKPGPAPKIALEKPSEFKLKNGLTVMVVENHKLPRVSYSLTIDNDPLANGDKAGVESLIGAMMGNGTTSISKDSFNDEVDFLGANINFSANGAYASGLSKYAERILELMSDAAINPLLTEEEFDKEKAKLIDGLKSSEKSVDAIAGRVGSALSYGKNHPYGELTTEETVNNVTFGDAVSYYESYFNPTKAYLVIIGDVEYKTIKKQIEKYFSKWEKLVNVEYTVPQAAPNVQYTQINFIDMPNAVQSDISLTNNVDLQMKDPDYHAVLIANKILGGGFNSYLNMNLREEHGYTYGARSGVGTDEFASRFSTSVQVRNMVTDSAVVNTIQEIKRIKEEPVEQDALKNAKAKYVGDFVLALESPQTIARYALNIKLNELPSDFYTTYLQKINAVTVEDVMRVSKKYFKTENARIVIVGKGSEVLTNLEKTGIPIQYFDKFANPVDKPVFSKEIPADMTAQKVVDNYIEAIGGMADLEKVKSVVNTANVTIQGAPYKPTAVIKMMSPNKMSMEMSIEGMGTVMKQKFDGTTGYQEQQGNRMPMTEDQIAENKAEMVLFPELSMDMSNLSLESIVPMEGTDAYKIKVTNGDKVSFRFYDVNSGLLVREEATTEAQGQSISTIQEYSDYTEVDGVMMPAVQKITTGPQVITMTSTEFKINEDVTDADFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHE1</accession>
    <name>A0A5C6ZHE1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF3843 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_07315</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024214">
        <property type="entry name" value="DUF3843"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12954">
        <property type="entry name" value="DUF3843"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="541" mass="63223" checksum="B99D94540D64918B" modified="2019-11-13" version="1">MKSRIYLKQWLHSKPEHYSSKTDLHYLKIANSIYLGLENNQKLVLKQFMDEADVASLCCFITCYYEDVISQTNIWKAFKTLYAKSYGKALPFYTLTEEYLDEEINAEDVAFLIWYFLNTIQGEKFVSPHNEFITNIAKQAMEVLNEDYEFAPENTVLKKFYQINSEHFDATDEFYQTRDFLYAVFFDSYLFYTDIKRRFEQDVFETIEDLSEEKPQMVMSYIREVTEAYTFSKSSALLALNAKDWASAVVGETDAHYKSLTSISQKVKGLFLYKSQTETDVTLEHIASGMLFKMTKKSFDSLEDIEEDYIIYIGLVKYNGEWWFSGNFSASPFNADLILDEKNSAKSRSEVSFLEDQAQMASIMEQQKQAFLDFNQGSLVAFLSAADLNPFLEAYMTFFNDSLKLSDQEKEAAHKRTKADGYFGNTAKEDPLEGEDKVFVVYFNPKSGIEFYDDIINAFPDERNSFFTEESREDVQYILMSATCSTEFTNYFVEHYKDRLDYFKSEPYKSYLNDLDFLLRFWKKDNYHTKSTVVLTGKDGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHG3</accession>
    <name>A0A5C6ZHG3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_14425</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="69" mass="7434" checksum="F0CC2EA3D4969086" modified="2019-11-13" version="1">MENFNTNLMKDQLSRVEMKTINGGKIADGCQSVVNGTRYTGLSVADAQGDYQFCVDNGYSSCGYCCASC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHN1</accession>
    <name>A0A5C6ZHN1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uracil phosphoribosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07840</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045922">
        <property type="entry name" value="DUF6341"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19868">
        <property type="entry name" value="DUF6341"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="75" mass="8987" checksum="0DBFEB84502B9725" modified="2019-11-13" version="1">MTDFFYGIEDLFVNVLFAPYDWLRALQLDSWWLANIFSWLFILVGFAAFVYWMLQLKKYTDSGEENKSITSHSYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHV4</accession>
    <name>A0A5C6ZHV4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0246 protein ESY86_12265</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">yaaA</name>
        <name evidence="2" type="ORF">ESY86_12265</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0246 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00652">
        <property type="entry name" value="UPF0246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005583">
        <property type="entry name" value="YaaA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30283">
        <property type="entry name" value="PTHR30283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03883">
        <property type="entry name" value="H2O2_YaaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00652"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="252" mass="28860" checksum="8CAE4D2D1A7E395C" modified="2019-11-13" version="1">MKLVLSPAKSLDYESKLPTTRATQPAFLDASGRLNKQLKKQSRKQLSKLMHISDNLADLNYERNQEFRLPFNKDNARPAIYAFAGDVYRGLDAYTIANEKIDGLQDTVRILSGLYGVLKPLDLVQPYRLEMGTKFPVGKHKNLYEFWKKDITAALNKELKDDELFINLASNEYVKAIDAKTLKVPVTEIKFQELKDGDYKTVAIYSKLARGLMARYIVENNAQTLEDLKGFDGENYRFTEKLSSDNELVFTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHY8</accession>
    <name>A0A5C6ZHY8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Xanthine dehydrogenase family protein molybdopterin-binding subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_13280</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000674">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036856">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008274">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037165">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012368">
        <property type="entry name" value="OxRdtase_Mopterin-bd_su_IorB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02738">
        <property type="entry name" value="Ald_Xan_dh_C2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036389">
        <property type="entry name" value="IOR_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01008">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54665">
        <property type="entry name" value="SSF54665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56003">
        <property type="entry name" value="SSF56003"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="Ald_Xan_dh_C" evidence="2">
        <location>
            <begin position="214"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="754" mass="82840" checksum="F9194195DF1E1498" modified="2019-11-13" version="1">MTKIKTSMGRRSFIKSVSLAGGGLIIGFNWLACQGPTEEGGKELAMQMPEEWFELNGYLKIGDNGIVTIYSPNPEIGQNVKTSMPMIVAEELDVDWNNVVVEQAPLNTEVFTRQLAGGSQSIRQGWQSLRTAGATARQMLLTAAAKQWEVPVLELSVENGIISHKNSDRTIGYGEIAKAAVNVEIPEEVELKNIDSFKIIGTSRKNVDAKKIVTGQPLFGIDTFKEGMLIAMIVQPPAFGMEFKTMDAAKAKGMPGIKDVFTIDTYPDDMEKEWSDVAAFSKLVVVVGESTWQVMQAKKEVKVEWDLNPKLVKQIEILEKSAGMDGVSGLESTSIHMTLMADVGSKKSEIVRRDGNPEKAFKNAARVIERSYTCPFLSHNCMEPMNFFADVSGGKAELLGPIQTPEFAEKSVNKRLGLDLENIDIQMTRMGGGFGRRLYGHFLVEAAVISEKMGTPIKLVYSREDDMTNGVYRPAYHVTYRAALDANNKLTAFHVNAGGIPESPLFANRFPAGAIENYLAESWSMESNISTGAFRAPRSNFIAGAEQSFLDELSEEMGQDPIQFRLDLLDRAGSNPVGEENDYDAARYAGVLKLARDKSGWDNTTGLSRGVAAYYCHNSYVAQILDLSVKNNQPSVDKVTCAVDCGIVVNPDAAKNMVEGGTIDGIGHALYSEMTFKDGVPQQSNFDTYRLIRHKEAPKTIDVYFIENGIDPTGLGEPPFPPIQGALANALYKATGKRFYDQPFISHMQDDLKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI46</accession>
    <name>A0A5C6ZI46_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF2891 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_06290</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021365">
        <property type="entry name" value="DUF2891"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11199">
        <property type="entry name" value="DUF2891"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="373" mass="42648" checksum="A93786E4A6083984" modified="2019-11-13" version="1">MKKQLLLILLTLTLFNCNTSEEKQTTANQQKLQMEVAKTPIINLEQANRLAQLPLNCIQTEYPNKLNQTIGSEADLQSPKTLHPAFYGCFDWHSSVHGHWSLVNLLKQFPELENRAAIEKMLLETMSEANIKAEVDYFYGKHNATYERTYGWAWLLKLAEELHTWDDPLARQLEQNLQPLTELMVANYEAFLPKLNYPIRVGEHPNTAFGLSFAHDYATTVGNSQLKSLIEQRAKDFYLKDAACPLSWEPSGFDFLSPCFEEAALMKRVLPMDEFKNWLSDFLPQLKDEKFTLDTGKVSDRTDGKLVHLDGVNFSRAWSLNEISRDLPEYAHLQNIANQHINYSLPSIVGDSYEGGHWLGSFALYALNSVARD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI47</accession>
    <name>A0A5C6ZI47_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_08735</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="185" mass="21674" checksum="D6584DF0E4F576D5" modified="2019-11-13" version="1">MKTYLKIVTVFVLIASCQSNKKEDINIVATLEREDTSQNNDMDTSKTQQQFSDFFPKELGEYKLIEVSEATVLSRTITSAFYLKGDNIKNNIVYNLEDGNKKGSSVLKDFEISYKYQNKGEGDTEYIYKERDGYKTIAFLQPEENRNEILFIYRQRFSIVLEGTEQPDKLWSYIKEEDLKKLDNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI55</accession>
    <name>A0A5C6ZI55_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08785</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022918068" evidence="1">
        <location>
            <begin position="22"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="308" mass="35178" checksum="4F0DEDEB98375804" modified="2019-11-13" version="1">MKSLRPFLSTLLLLICFSNFAQTPEQQEMMVKAERMRDSIMNTPEMKAMMKQANELEKKQKSNVKTSPIPKAIKTEDKYWKNTLVSIHNNKLTNWNLGAADLVFNYSYDSRNDKLNSVKVGTIKADGTIALNPTSKVPDLKPLSNFKNSNVFFDIHDPASYQFTNEATGFKLNSYVLVYQNNQKIGVLTIGNSEKVTLNLLTSGDLYYGDEGYMLSWAYVEKDCAIKANEHWKGDLSNTGTPLIVETNVVYDLSFKTGWNLVKTEVIGKYEFPNAPEEDRSRYKKHKHTVVPSIPVEATYYFRKSLQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI71</accession>
    <name>A0A5C6ZI71_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Elongation factor P</fullName>
            <shortName evidence="7">EF-P</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 11" type="primary">efp</name>
        <name evidence="11" type="ORF">ESY86_10400</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Protein biosynthesis; polypeptide chain elongation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7 8">Belongs to the elongation factor P family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00345"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04470">
        <property type="entry name" value="S1_EF-P_repeat_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05794">
        <property type="entry name" value="S1_EF-P_repeat_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00141">
        <property type="entry name" value="EF_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015365">
        <property type="entry name" value="Elong-fact-P_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020599">
        <property type="entry name" value="Transl_elong_fac_P/YeiP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013185">
        <property type="entry name" value="Transl_elong_KOW-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001059">
        <property type="entry name" value="Transl_elong_P/YeiP_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013852">
        <property type="entry name" value="Transl_elong_P/YeiP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011768">
        <property type="entry name" value="Transl_elongation_fac_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30053">
        <property type="entry name" value="PTHR30053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01132">
        <property type="entry name" value="EFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08207">
        <property type="entry name" value="EFP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09285">
        <property type="entry name" value="Elong-fact-P_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005901">
        <property type="entry name" value="EF-P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01185">
        <property type="entry name" value="EFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00841">
        <property type="entry name" value="Elong-fact-P_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00038">
        <property type="entry name" value="efp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01275">
        <property type="entry name" value="EFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7 11" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="6 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EFP" evidence="10">
        <location>
            <begin position="67"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="Elong-fact-P_C" evidence="9">
        <location>
            <begin position="130"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD88900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="188" mass="21128" checksum="297AF60644D79E3F" modified="2019-11-13" version="1">MASTSDIRNGLCIRYNHDIYKITEFLHVKPGKGPAFVRTKMKSVTTGKVLDNTFSAGHKIEDVRVETHKFQYLYHDGEFFHFMNQEDYTQIRLTEAALDRPDLLKEGEVVTVLINTEDNMPLSVDMPASVVLEVTHADPGVKGNTATNATKPATVETGAEVNVPLFINEGDKIRIETEKGTYKERVKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI97</accession>
    <name>A0A5C6ZI97_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA ligase (ATP)</fullName>
            <ecNumber evidence="2">6.5.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">NHEJ DNA polymerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="primary">ligD</name>
        <name evidence="16" type="ORF">ESY86_06925</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.1" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003910">
        <property type="term" value="F:DNA ligase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012309">
        <property type="entry name" value="DNA_ligase_ATP-dep_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012310">
        <property type="entry name" value="DNA_ligase_ATP-dep_cent"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014146">
        <property type="entry name" value="LigD_ligase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014144">
        <property type="entry name" value="LigD_PE_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014145">
        <property type="entry name" value="LigD_pol_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014143">
        <property type="entry name" value="NHEJ_ligase_prk"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04679">
        <property type="entry name" value="DNA_ligase_A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01068">
        <property type="entry name" value="DNA_ligase_A_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13298">
        <property type="entry name" value="LigD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02777">
        <property type="entry name" value="LigD_PE_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02778">
        <property type="entry name" value="ligD_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02779">
        <property type="entry name" value="NHEJ_ligase_lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02776">
        <property type="entry name" value="NHEJ_ligase_prk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50160">
        <property type="entry name" value="DNA_LIGASE_A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="8" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 16" id="KW-0436">Ligase</keyword>
    <keyword evidence="11" id="KW-0464">Manganese</keyword>
    <keyword evidence="12" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA_LIGASE_A3" evidence="15">
        <location>
            <begin position="292"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00029943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="TXD89925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="810" mass="92170" checksum="DC6DF115627915FA" modified="2019-11-13" version="1">MSLSDYRRKRNFDDTPEPRDEESTENGFRFVIQRHRASHLHYDLRLELEGVLKSWAIPKGPSMNPNDKRLAIHTEDHPVAYLHFEGVIPKGNYGAGVMHIWDEGHYKNHNEKERLSNAYAAGKLKITLIGSKLRGIFTLVRSSSKNRENQWLLIKHQDEFATALQYDAENFIDETYLKNKTQDAANLSLNSLVNPMLASPGKTIFNDKNWIYELKYDGYRALANLQHSKITLYTRNGISLNQKFKSIATDLATIEHNAILDGEIVLLNKAGIPQFSALQNYDPLTSEGSLVYYVFDLLHLNGHDTITLPLLDRKQLLKELLPKSNHVFYCEHVEAMGTAIYKKAVDMGMEGIIAKKGNSEYDLNNRSPNWLKFKKFESTEAIICGYTLSKSAGRAFGALILGMINTDGLVYVGTCGSGFSEEQLKHLHNKFELLVRDEPVFKIAKHLKGRTAVWLRPKLLCEVKFAEWTSANVMRHPVFLRLREDKMLDVDAQTESALDQISDSKKVSSEFTLDVDARSLNISHVDKLYWPSLPKTKYDLLDYYIKMAPYILPFLKNRPESLLRHPNGVSHEPFYQKDASDFPSWIEKTHIISKSGEKGIDYALCQDKASLLFLNNLGCIEMHPWHSTIFQLDKPDYAIIDLDPSEENSFEEVIETALVAHDILKSAKIKSFCKTSGASGLHIYVPMGGLYNYEQARDFIKLVCLCIQQRLPTLTTMERSLKKRGSKIYLDYLQNRKGQTIIAAYSLRAKPLATVSTPLNWEEVKTGLKVEQFTIDSVPKRMLKNKDVFLGILEEGIAMGEAIDALNTGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZID5</accession>
    <name>A0A5C6ZID5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_06795</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="121" mass="13159" checksum="6A8D1BB3B9BCD5D8" modified="2019-11-13" version="1">METTAVSGSWRITNLNDSGQDETSDFAGYEFTFNSDGSLVAINGTITMTGTWSITDDTNSDDDSSNDDGIEFNIFFPVPDTNDFEDLNDDWDILSTSSTKIELIDISGGNGGTDLLTFEKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIF8</accession>
    <name>A0A5C6ZIF8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alkaline phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the alkaline phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16012">
        <property type="entry name" value="ALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001952">
        <property type="entry name" value="Alkaline_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11596">
        <property type="entry name" value="PTHR11596"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00245">
        <property type="entry name" value="Alk_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00113">
        <property type="entry name" value="ALKPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00098">
        <property type="entry name" value="alkPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="467" mass="52071" checksum="633CBB61215B23A3" modified="2019-11-13" version="1">MNRRKFFKNGSILTLGTTLLHPFSSIANTIPYKEGTRNKKAKNIIIIVSDGMSIGTLNMTDLYLSRKTGKCSNWLQLYKENKVNRALMDMASASSIVTDSAAASASWGGGVRTNNGSLNVSENGEEYMPLWQKFKQVGKKAGCVTTVPITHATPAGFCINSKSRNAQEEIAEKYLEQKFDLMMGGGDNYFSPEKREDKKDMYQAFASQGYEVVKTRAEMFSASNGKPILGVFDADGLPYSMDRQNNKELLQKVPTLAEMTQKAINAMSNHPNGFVLQVEAGKVDWAAHGNDIAALIYDQVAHDEAIQVAMDFAEQDGETLVIITTDHGNANPGIIYGNEANVNFDSIQEYKHTNEWILNGIGKETSISQIKERVYYANNFALTDEESHQLLRYYTDLQTEDGLYNPRHLPFQDLAKMQQQHNSVGWISMQHSADYVELAMYGPGSSLLKPFVKNTDLHYLMLEAAEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIT3</accession>
    <name>A0A5C6ZIT3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nitronate monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06195</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018580">
        <property type="term" value="F:nitronate monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04730">
        <property type="entry name" value="NPD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004136">
        <property type="entry name" value="NMO"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03060">
        <property type="entry name" value="NMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NMO" evidence="1">
        <location>
            <begin position="3"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="315" mass="33825" checksum="0B2CD8486A28E54F" modified="2019-11-13" version="1">MSTKLTQLLQIKYPIIQAPMFLVSNVAMVTEAMNSGIAGCIPALNYRTLEELRAAAKSLKANKVGQGAFGFNLIVNKSNLKYKDQLTVICEEGCDFIITSLGSPEETIKKAHAAGIKVFCDVTDLHFAKKVESLGADAAIAVNNEAGGHRGNLSPKDLIQQLTANISIPVISAGGVGTKADLDLMLSYGAEGVSIGSPFIASEEAEVTKEYKQACVDYGAEDIVMTQRISGTPCTVINTPYVQKIGTKATWLETLLNKSKTLKKWVKMIRFAIGMRATEKAATQATYKTVWVAGPSISHTNAILPVKEIVKNLTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ19</accession>
    <name>A0A5C6ZJ19_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_09685</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="194" mass="22239" checksum="F961E5ACA1B78344" modified="2019-11-13" version="1">MKKLLFIAAVLIGTLSYGQSQTKQSYRNSQGEWILSVGVNALGNLGTRNPVEKLDEFKLKNPLALAIEHRWTKYLSIEQDVSFNGYDKGEFLDNGFLEDDVLYFSTNTSLKFYFSDYLYDAEWVDLYASGGVGIFTIDELNTSANVSFGALFWLNRNRTIGIRFQGTGKFAFNHPDKQFDNNHWMYFAQAVFRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ31</accession>
    <name>A0A5C6ZJ31_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PDZ domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041489">
        <property type="entry name" value="PDZ_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17820">
        <property type="entry name" value="PDZ_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="SSF50630"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="1">
        <location>
            <begin position="355"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="451" mass="51725" checksum="04CE039E79CA5877" modified="2019-11-13" version="1">MIITYIKYALCFFIFTLGAPEVFAQNKFNLPTKDQDKIRFELINNLIILPVELNGVKLSFLLDSGVSKPILFNITNTDSLQINEVETIFLRGLGGGEAVRALRSRRNFIKIGDAININQDIYVVFDQSINFTPRLGVPIHGIIGYDLFKDFVVEINYRRKFIKLHKPETYTYKDCRKCTSFNLNFHNDKPYIEGNIEIADQSKKVKLLIDSGSSDGLWLFENDSIGIISDSINYFEDFLGRGLSGNVYGKRSKIDAFSLDKFQLTNVNVAFPDSTSISHARLIQDRNGSLSGEILKRFHVIMDYPNSKISLRKNKNFNDDFRYNRSGIVLEQRGQRIVQERNSAPVFDSYGNDKRVAFVIDRAGYYSYKLQPAFKIVDLRKNSPAEKSGLMTNDQLLSINGKSTLNLKLEDIMGFFQADYGKTIRVTIERDTEIMKFQFDLENPFKQEKLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ34</accession>
    <name>A0A5C6ZJ34_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNA polymerase sigma factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_05325</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="22"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="279" mass="32141" checksum="8D7A6CD9EE3AE5C8" modified="2019-11-13" version="1">MKTENNNLEKALEGDIKAFQSLFAEFQPQLKSYLYRLLTDRNDTDDLTHDTFVKAFDKISTFKGNSAFKTWVFQVATNLAYDFLKKKKRWLPNAQDQAKSLAMSTEYIQQLFVMTNQTSNRGRYEVKEHIDFCFTCISKTLTLEEQIALILKDIYAFSRTEIAHILGKTEGVVKHLLFNGRKTMIEIFDNRCALINKNGACHQCTELAGIYNPKQTKQEELMKIKLVKSAKKEPKEKLYQLRADLVAAIDPLNSEGADMQNIIMQCTRLAIDEIETIQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ37</accession>
    <name>A0A5C6ZJ37_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase family 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_09790</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="11"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="294" mass="33908" checksum="87BC210CF188047A" modified="2019-11-13" version="1">MNSKLKQPLVSVLMTVYNREKYIGEAIDSIIASTYDHWELIIVDDSSIDGSVAIAKSYAEKDKRINVYVNDKNLGDYPNRNQAASYAKGKYLKYVDADDMIYPHGLELLVYYMEQFPESGYGLCSLPQDKFRKFPFQLNPKEAYQRHYFEQALFHKAPLSAIINRQIFNERGGFTGKRMLGDFEMWNLLSQTHSVVLMPHGIAWYREHDEQEMADHRTDPMHPFKYILLAEDLLKSPSCPLEDREKVQALKNNKIQQANAILSAFKHHGKGKAMELSRASGISLYKAINLKFIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ82</accession>
    <name>A0A5C6ZJ82_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Gliding motility protein GldM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">gldM</name>
        <name evidence="4" type="ORF">ESY86_05665</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019859">
        <property type="entry name" value="Motility-assoc_prot_GldM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022719">
        <property type="entry name" value="Motility-assoc_prot_GldM_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022720">
        <property type="entry name" value="Motility-assoc_prot_GldM_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12080">
        <property type="entry name" value="GldM_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12081">
        <property type="entry name" value="GldM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03517">
        <property type="entry name" value="GldM_gliding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="GldM_N" evidence="3">
        <location>
            <begin position="31"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="GldM_C" evidence="2">
        <location>
            <begin position="337"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD90224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="521" mass="56627" checksum="4D940879454A3ABD" modified="2019-11-13" version="1">MAGGKLSARQKMINLMYLVFIAMIAMNMSKEVLSAFGLMEAKFEESNETMTEMNTKLLANLETKAEEKPAEFATAAEKAKQISTVSDEFFNYLESLKSNITKTGDYKVDPKTGKLPFEEMDKTDILDEAWFTGDRLTKEGQEFMEKIAAYKAEVKKIIGDDVKYTRAIENFEKRFNTTPKTNTDGKKIEWLDYNFKGFPAIASYTKLTALQNDVKVTEANMFNVFLGNTLDEAVSLKNYTAIVIADKSAFFAGEKFQGKVVLGKYANVTPTGLSIGGQSVDLEEAIDSTGAARLDFNVGGVGEQKIDGTFTFLEDGKALEIPIKGNYVVVPRPNSATISADKMNVVYRGVDNPMTISFAGVPDNKVTANGAGLTKASGMGKYTMKPTSGREVAINVSATLDDGSKVNDKAVFRIKDIPKPSGQIAGQIGTAKLPRKNVEIGRIEAVLEDFDFDLPLTVTGFKIKVEGKPSITVSGDRLNGAAKAALSSAPRGSQVQIFEIKSRTNGPAIKPANPLVIELTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ84</accession>
    <name>A0A5C6ZJ84_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 9">Catalase-peroxidase</fullName>
            <shortName evidence="8">CP</shortName>
            <ecNumber evidence="8 9">1.11.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Peroxidase/catalase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 12" type="primary">katG</name>
        <name evidence="12" type="ORF">ESY86_06440</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8 9">
            <text>2 H2O2 = 2 H2O + O2</text>
            <dbReference type="Rhea" id="RHEA:20309"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="EC" id="1.11.1.21"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>AH2 + H2O2 = A + 2 H2O</text>
            <dbReference type="Rhea" id="RHEA:30275"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="EC" id="1.11.1.21"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
        <text evidence="8">Binds 1 heme b (iron(II)-protoporphyrin IX) group per dimer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer or homotetramer.</text>
    </comment>
    <comment type="PTM">
        <text evidence="8">Formation of the three residue Trp-Tyr-Met cross-link is important for the catalase, but not the peroxidase activity of the enzyme.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the peroxidase family. Peroxidase/catalase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.21" evidence="8 9"/>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004096">
        <property type="term" value="F:catalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01961">
        <property type="entry name" value="Catal_peroxid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000763">
        <property type="entry name" value="Catalase_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019794">
        <property type="entry name" value="Peroxidases_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30555">
        <property type="entry name" value="PTHR30555"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00460">
        <property type="entry name" value="BPEROXIDASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00458">
        <property type="entry name" value="PEROXIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="SSF48113"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00198">
        <property type="entry name" value="cat_per_HPI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00436">
        <property type="entry name" value="PEROXIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8 9" id="KW-0349">Heme</keyword>
    <keyword evidence="7 8 9" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="6 8 9" id="KW-0408">Iron</keyword>
    <keyword evidence="4 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 8 9" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PEROXIDASE_4" evidence="11">
        <location>
            <begin position="148"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="8">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="8">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <feature type="cross-link" description="Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with Trp-114)" evidence="8">
        <location>
            <begin position="237"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TXD89836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="750" mass="83039" checksum="BA975CF59B1C275A" modified="2019-11-13" version="1">MENKSESNAAPQGKNFDINEQAPQCPFMGSPHQKTAGGGTTNRDWWPNELKLNILRQHSNKSNPMGDDFDYKKEFNSLDFSALKQDVIDLMTDSQEWWPADYGHYGGLMIRMAWHSAGTYRIGDGRGGASAGNQRFAPINSWPDNGNLDKARLLLWPIKQKYGRKISWADLMILAGNCALESMGFKPFGFAGGREDVWEPEQDIYWGSETEWGANDERYADGELEAPLSATLMGWIYVNPEGPNGNPDPMGSAANVRETFGRMAMNDEETLALSAGGHTFGKAHGAADPSVYVDVEPASAGIEEMSMGWRNSYKSGVLDDAITSGLEGAWTPNPIQWDHDYFEVLLNYDWELTKSPAGAHQWRPTEASQARMAPMAGDASKKQQLMMTTADIGFKVDPKYLEISKRFHKDHKAFEDAFAKAWYKLTHRDMGPVSRYLGPDVPQEELLWQDPIPKVDHDLVDASDIKHLKQLVLDSGLSVSELVTTAWASASTYRDSDKRGGANGARICLLPQKNWEVNNPEQLDKVLTALKRVQADFNGSQLGNKKISMADLIVLAGCAGVEKSAKAAGHEIEVPFHAGRTDATQEQTDIDSFGYLEPKADGFRNFMNEHQKLAPEEALVDRAQLLTLTVPELAVLVGGLRVLGANHSGTNYGVFTERVGTLSNDFFKNLLDLSLTWKAATSEDKAFIGRDRKSGTMKYTGTRADLIFGSNSELRAVSEAYGSVDSEAKFVKDFVAAWSKVMNLDRFDLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ96</accession>
    <name>A0A5C6ZJ96_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase S41</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_06400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00245">
        <property type="entry name" value="TSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TSPc" evidence="2">
        <location>
            <begin position="294"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="243"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="550" mass="62855" checksum="FB08414B0A5AC051" modified="2019-11-13" version="1">MIKKIVLTLCTLIVLVSCGSIEKYNLQVTQLHPVKDVHEDIDKAYTQLQRHHPRLYQYVPKETLDFKFDSLKKAINEPMDGRTFYKQLAMVTKHIGQGHTSISPPSTKLSRDQRKELLKTRFDISYLSFEYLDGKLFITDAVGKDSVLINAEILKIEDESSQDLIRKYKDLIASDGYNTTFHNRVVGNRFLRYYASDKGRFDSISLTLRNADSTFVKNYKRRPLRDQLQIKNDSIKRDSIKLANKTKPKLTKAERKAKKLENKAKRKYNSKYGFVPTPNMPNVKNYTRNLNFVGKDSTVAMIKIKGFQNGNYKGFYDDTFTVLDSLKTEILILDLRNNFGGRLNEIEYLYGYLTDENYTFLNKSETNTRFPILKSLMSNSNSLGLKMFAGLLSPGLAMADVLRVSKKDGQLYRKFKSAQEQEPKPLNFNGKVYVLINGNSFSASSVLASQLHGTNRATFVGEETGGAYNGTVAGLFKIYELPNTKVEVRIGLMKIDTKQKVDTDGYGVKPDVEIIPTYQDRLNHIDPELEWVLKDIEAKKGINNAANYRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJF0</accession>
    <name>A0A5C6ZJF0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_04810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="4"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="366" mass="41501" checksum="62BD449B34FB8CDE" modified="2019-11-13" version="1">MKLSVVILNYNVRYFLELCLKSVEAALVAIDSEIIVVDNHSADDSCAMVKQLFPKVKLLENKENLGFSKGNNQGVAIAKGEYLCILNPDTVVAEDTFTSLLHFAETQNKLGILGCKLIDGQGQFLSESKRHVPTPWVSVKKMLGFTAAYYVPELDADGVGEIEILVGAFMLLKRAVYNEVGGFDEAYFMYGDDIDLSYKTLKQGYQNSYFGKTTVIHYKGESTLKDKVYAKRFYGAMQIFYKKHFKANPIFNIMVWIGIRLASVMQKPEIVHKSVPKQRFFISEEKNEALQNRLGQALEVRKSLESYLDDSEFILNNNDLSFKRIIEIIDHKPKNCSARFKILPKNSNFILGSDSSKYQGEVITFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJI4</accession>
    <name>A0A5C6ZJI4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4252 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025348">
        <property type="entry name" value="DUF4252"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14060">
        <property type="entry name" value="DUF4252"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022700760" evidence="1">
        <location>
            <begin position="23"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="181" mass="20269" checksum="7EBBE6AAF6A8C721" modified="2019-11-13" version="1">MALSTSKILVLLILVVTLQSCDQEPTLQSFYVDNELSQGFTSLDVPVSMLKIDEDALTETQKEAYESVEKLSMIAFVLDETNKAEYEIEFAKVQTILKNPKYEELMRGGNTTDGKFQVSFVGKEDSVEEFVLLGNSNEKGFALVRVLGDDMNLDKIMKLSTVLSSADMDSSQLEEFMGFFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJV6</accession>
    <name>A0A5C6ZJV6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">AAA family ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_08130</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="3">
        <location>
            <begin position="33"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="263" mass="29842" checksum="45475D18EEBCAFBB" modified="2019-11-13" version="1">MAYLSTLNINTTRQHPFPFDVPAIKFAKDIDLSSQITFLVGENGTGKSTLLEAIACRLQLPHMDGAGYGKASFDAAKTLMPFLDLTWNIERSLGFFFRAEDFGDYLNSVHRAGTNIEQQMGDMGDEIPKHIIEDMKDSANHQLRGMRFKYGQELNAFSHGEAYLHIMNQTITARGIYLLDEPEAALSPARQLTLIYFIQNHLKHFNSQFIIATHSPMLLAYPNATIYEITENAMQKTALEATEHYNVTKSFLNNPKAYLRHFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJX3</accession>
    <name>A0A5C6ZJX3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">3'-5' exonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07545</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019288">
        <property type="entry name" value="3'-5'_exonuclease_PolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10108">
        <property type="entry name" value="DNA_pol_B_exo2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_pol_B_exo2" evidence="1">
        <location>
            <begin position="61"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="237" mass="27918" checksum="685A8C9FA2946C18" modified="2019-11-13" version="1">MISKLNLENILFLDIETVPETEYFSELDHTKQELWEHKSKYQRREDFTAEAFYDRAGIWAEFGKIICISVGYVKMEADVRTFRVSSFSGNEIKILKDFKNLIITHFSQTKHLLCAHNGKEFDFPYIARRMIIHNIELPHKLNLFGKKPWEVPHLDTLELWKFGDYKTYTSLKLLTNVLGIPSPKDDIDGSEVYRVYYKEKELDRIIAYCEKDTIAVAQIFLRLRGDTLLHDNEIMSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK14</accession>
    <name>A0A5C6ZK14_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8 10">FAD:protein FMN transferase</fullName>
            <ecNumber evidence="2 8 10">2.7.1.180</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Flavin transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">ESY86_06050</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8 10">
            <text>FAD + L-threonyl-[protein] = AMP + FMN-L-threonyl-[protein] + H(+)</text>
            <dbReference type="Rhea" id="RHEA:36847"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11061"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:74257"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.1.180"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="9">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="9">Magnesium. Can also use manganese.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8 10">Belongs to the ApbE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.180" evidence="2 8 10"/>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017013">
        <property type="term" value="P:protein flavinylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024932">
        <property type="entry name" value="ApbE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003374">
        <property type="entry name" value="ApbE-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30040">
        <property type="entry name" value="PTHR30040"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02424">
        <property type="entry name" value="ApbE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006268">
        <property type="entry name" value="ApbE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143631">
        <property type="entry name" value="SSF143631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0274">FAD</keyword>
    <keyword evidence="4 8 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7 8 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 10" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="276"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="280"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR006268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR006268-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD90296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="323" mass="36074" checksum="198146869603B784" modified="2019-11-13" version="1">MKHLPYLVVIFLCFACNNEPENTKLSGPVFGTSYNVIYDSTEGYTKQFDSLFTIINQSMSTYIPDSDISKINRNEDAFVDSHFIKVFEASKEIYQKTNGVFDPTIGAVVNAWNFGPEGRIQDLDSLKIDSLMLSVGLDRVSLNGNKIIKPKATFIDFNAIAKGYGVDVIADFLESQNIENYLVEIGGEIRCRGINTEKQQAWRVGLDQPRFDGENSVYKAINLKDQAMATSGTYRKFKTDAQGKRYAHIINTKTGYPSKTNILSVSVIAENCMVADAYATAFQAMEVGAISSFLEYHPEMKAFLIIENESNELENVSLNGFPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKF0</accession>
    <name>A0A5C6ZKF0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HigA family addiction module antidote protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013430">
        <property type="entry name" value="Toxin_antidote_HigA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36924">
        <property type="entry name" value="PTHR36924"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02607">
        <property type="entry name" value="antidote_HigA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="28"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="100" mass="11479" checksum="210333D2B75D45C0" modified="2019-11-13" version="1">MEKLANIHPGKILNQEFLEPLEITAYRLSKDLSIPQTRISEIIKGKRRITSDTALRLSKYFGNSAKFWLGLQNDFDIEEGQQSKASELNQIKHYSDKNVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKG1</accession>
    <name>A0A5C6ZKG1_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6265 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_03730</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046232">
        <property type="entry name" value="DUF6265"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19780">
        <property type="entry name" value="DUF6265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023105062" description="DUF6265 domain-containing protein" evidence="1">
        <location>
            <begin position="18"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6265" evidence="2">
        <location>
            <begin position="37"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="163" mass="18578" checksum="C102CC95AAD2C452" modified="2019-11-13" version="1">MKTVALLFCLCVFQLQAQTIDSTSVEKPLEPKLENIAWLAGSWHGEAFGGQTEEIWSKPSGGSMMASFKLINDGKVSFYELEIIREIENSLILQLKHFDGELKGWETKDETIDFPLKKLTAKQMIFDGMSFKRVSDTEMNVFVDIKNENGDVDLVQFNYKKVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKT0</accession>
    <name>A0A5C6ZKT0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="183"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="228"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="265"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="298"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="356"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="394" mass="44144" checksum="A081E07FC5E6D137" modified="2019-11-13" version="1">MKDFFRLVRAEFKRIFSNNVLLAIFIGAPIFYGIIFGYVYQQGNVVGLPIVIVDQDNSPTSDKIIDAFSDNEVLLISDVRYTPGNILAEMPTNQYAAVITLPTNFEADILQKRHPEIRVDLNMANMVNANTASKSIQSVLMTLNAGIEIEGLKKSGLHPTQAAAAYESFKINFNKLYNSTGNYVTFMLPGMLAAIMQQIIFLAMALVFSRDFEDGYFGSLVEESRFSLYHIAIKSTPFFLMIPIMWAIVSLFIPYFQIDADVFNFPMLILVTLLTLASMFIGMLFSIAIPSQLKATELLMVISTPAFVLSGFTWPTLAFPDAIANVAQYIPLTQFLSAFRKIAFYGGDTASITPEINILLTIIFVTFIAMVLLLQFKIYRYRKNLKATLTPTQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL65</accession>
    <name>A0A5C6ZL65_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">LPS-assembly protein LptD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_00380</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045659">
        <property type="entry name" value="LptD_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19838">
        <property type="entry name" value="LptD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LptD_2" evidence="2">
        <location>
            <begin position="245"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="762"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="763"/>
            <end position="783"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD91088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="926" mass="104753" checksum="84156E65879071D8" modified="2019-11-13" version="1">MAIQIPSHTLAKIHLKALHTKSFPILFSLSFTVFINMFCFAQDLPITRKPIKPVSELNDTLRLAIDTLTLPATRPIKLTENDSIKNDTLPKQKETLTAIVNYKATDFVRLNQKLNQTTLYNEAKVDYGDMNITAGIIVIDHSSKTVYAGRIKDSAGVYTQKPVFTQGPNIIEPDSIIFNTDTKKALIFNSKTEQSGGTIVAEVTKRENDSVLFMKNAIYTTAENLDDPEYYFKMRKAKVVPGKKVVTGLTNLFIYDVPTPIGLPFAYFPMSKDQTSGVIIPTPGQDLGSSDRGYNLQNGGYYFAISEYFDLAVLGDYFTNGSYGLRLENSYALRYRFRGNLSIRYENLINSERGFPDFSKSTIYNIRWSHTQDAKANPNSRFSASVNLGSSRYFQQSINQNNLAQTQNNTLASSVSYSKTFPGEPQVNMNVTATHSQNTNTQDINLTLPTFQGSVSRIFPFAPSVGTKKGIIQNINLQYNVRAENRINTNDSVFFKSEMFDDAKIGAVHSVPVSTNFKVFKYFSMSANANFEENWTYNTINKFQDEEGDIITEDLNGFDRFLTYNFSTSIGTTIYGLFDFEKEGRDPKIQKIRHVMRPSISYNINPAFDQYYDTFEVVDANGTTVGDMRREEYTRFQGSLFGTPGNNFSSAMRLSVGNNFEAKVRSNDSTATEPEKIKLLDNLNFETSYNFAGDSLKISAVRVSGGTTILDNKMNINFGAILDPYALDNNNQKIDKFNINNGGSLFRLTSANFNVSYSITSDSFDREPEDDRGRDESLRSGGRDDDLFGTTQDFADQRLSDDDDDEEEEISEFYNFSIPWKLRLAYAATYSNAARQNTISNNSLMFSGDVELSPRWSVGVSSGYDFVNKGFTQTQFRFERDLLSWRMNFSYVPFGPYSQWNFFIGISSSMLQDLKYDKRRQPDQRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLB9</accession>
    <name>A0A5C6ZLB9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Thioredoxin-dependent thiol peroxidase</fullName>
            <ecNumber evidence="5">1.11.1.15</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_06120</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.15" evidence="5"/>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024706">
        <property type="entry name" value="Peroxiredoxin_AhpC-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000239">
        <property type="entry name" value="AHPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1 5" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="4"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate" evidence="3">
        <location>
            <position position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000239-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD89780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="151" mass="17162" checksum="C6ABEC07BA9A7FE0" modified="2019-11-13" version="1">MTELKVGDKAPDFSAKDEQGNTITLQDFKEKKLVLFFYPKASTPGCTAEACNLNDNFERYKNQGYAILGVSADSEKRQSSFKNKYDFQYPLLADEDKKVIEAYGVWGPKKFMGKEYDGIHRTTFIIDEKGLIEDVISKVKTKDHTAQILSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLG4</accession>
    <name>A0A5C6ZLG4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">T9SS type A sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_01705</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004062">
        <property type="term" value="F:aryl sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010262">
        <property type="entry name" value="Arylsulfotransferase_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05935">
        <property type="entry name" value="Arylsulfotrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022745668" evidence="1">
        <location>
            <begin position="19"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="domain" description="Por_Secre_tail" evidence="2">
        <location>
            <begin position="465"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="531" mass="59572" checksum="55EA62F67BFCB4B6" modified="2019-11-13" version="1">MKKLVLILFAVISGSAISQETVGLVFNEINENKSEGYTLFKPSSDNRAFLIDNCGEVVNQWNFFGEGSRNCYFLEDGTLLQSNDLYAELRDWDNNVLWSIDYEALLGFRIHHDIEPLPNGNFLVLVRDGYTNNEMFAEGMDTSYPNDVLLLERILEIEPVGTNSANIVWEWKLFDHLVQDFDSTKPNYGIVADNVQLLDMNYDGGHGSNPIHANAIDYNEDLDQIAVSARHLSEVFIIDHSTTTAEAATHSGGIYGKGGDFLWRWGNPEVYDMGTIDNKKLGRQHDIKWITEGPNQGKMSVFSNDGYGSNLTASSVHIIDQNDTNGFYSLNSGKFLPEDYFWSWNGTIMNEVMHAGAQCGVQIMSNGNALINESDNGRLSEIDNSGNVVWVYIIPAGNNSEFDQFTEPIGNGSFRAHRYSESFSGFENISLNSSSGIIENINSISENCSQSLSLVKNDLVNLTYYPNPTKDYLYFSSYKKIDKIEVFGLSGNIIITRSNVDFINLKSLANGMYLINILHDTKSRFIKVLKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLI2</accession>
    <name>A0A5C6ZLI2_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Aminomethyltransferase</fullName>
            <ecNumber evidence="3 7">2.1.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 7">Glycine cleavage system T protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">gcvT</name>
        <name evidence="10" type="ORF">ESY86_03880</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">The glycine cleavage system catalyzes the degradation of glycine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>(6S)-5,6,7,8-tetrahydrofolate + (R)-N(6)-(S(8)-aminomethyldihydrolipoyl)-L-lysyl-[protein] = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + (R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:16945"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:10492"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="ChEBI" id="CHEBI:83143"/>
            <dbReference type="EC" id="2.1.2.10"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">The glycine cleavage system is composed of four proteins: P, T, L and H.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the GcvT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.10" evidence="3 7"/>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004047">
        <property type="term" value="F:aminomethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019464">
        <property type="term" value="P:glycine decarboxylation via glycine cleavage system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00259">
        <property type="entry name" value="GcvT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006223">
        <property type="entry name" value="GCS_T"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022903">
        <property type="entry name" value="GCS_T_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028896">
        <property type="entry name" value="GCST/YgfZ/DmdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013977">
        <property type="entry name" value="GCV_T_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006222">
        <property type="entry name" value="GCV_T_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029043">
        <property type="entry name" value="GcvT/YgfZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027266">
        <property type="entry name" value="TrmE/GcvT_dom1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43757">
        <property type="entry name" value="PTHR43757"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01571">
        <property type="entry name" value="GCV_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08669">
        <property type="entry name" value="GCV_T_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101790">
        <property type="entry name" value="SSF101790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00528">
        <property type="entry name" value="gcvT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GCV_T" evidence="8">
        <location>
            <begin position="6"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="GCV_T_C" evidence="9">
        <location>
            <begin position="276"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD90515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="356" mass="39225" checksum="41624D10A00926AC" modified="2019-11-13" version="1">MKNTALTATHEALGAKMVEFAGYNMPIQYDGLKIEHEAVRTGVGVFDVSHMGEFLIEGPNALALIQKVTTNDASKLRIGKAQYTCLPNDDGGIVDDLIIYMIEEDSYLLVVNASNIEKDWNWISSKNDVDAKMRDLSDNYSLLAIQGPKAIETMQALTSHDLSSIKFYNFEIGDFAGVPHVIISATGYTGSGGFEIYCKNDQVQQIWDKVVEAGAKPIGLAARDTLRLEMGYCLYGNEIDETTSPIEAGLGWITKFTKRFTNSENLSEQKQSVLKRKLVAFELTEKGIPRNGYDIVDLEGKLIGKVTSGTMSPSLNKGIGLGYVETKYSDFGTGIYIQIRKNAVPARIVKLPFYKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLU0</accession>
    <name>A0A5C6ZLU0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06790</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022809411" evidence="1">
        <location>
            <begin position="27"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="143" mass="14949" checksum="0E4D888B81402FA7" modified="2019-11-13" version="1">MKNFKYKFIILTIISLAFLAISCSNDDDNNNVSANVTLTEGIDGDIGGDFTGNGGSTSETFNWQNGLSTADYNADITASSTGLFQMIIKDSEGTTVLDRSLNGNVEPDSFSGVTSAGQAGMWTVTITVSNFNGDGSFSLSAGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLV5</accession>
    <name>A0A5C6ZLV5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta fold hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003140">
        <property type="entry name" value="PLipase/COase/thioEstase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02230">
        <property type="entry name" value="Abhydrolase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Abhydrolase_2" evidence="1">
        <location>
            <begin position="15"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="215" mass="24189" checksum="EE6B41CAD97FC436" modified="2019-11-13" version="1">MTSTLDYITRPSSLKDNAPLLIMLHGYGSDENDLFSFAQELPEELFIISLKAPYAMQPFGNAWYAINFDAQQNKWNDVEQAVASRDLIANFIDEACAEFPVDKSNLTLLGFSQGTILSYAVALSYPEKVKNVIALSGYVSEDMLKDDLSSKDYSHLDFYCSHGSVDQVIPVEWARKAPKFLNALNIKHSYAEFPTGHGVAPQNFYELRSWLGKRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLZ4</accession>
    <name>A0A5C6ZLZ4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_00265</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="191" mass="22512" checksum="B296BA16FB4AF5ED" modified="2019-11-13" version="1">MSAQNKVIPESIVDNVEKALTYYPQLEDTNIEFRFKKNIKKSTMQARPTIGSFFRTRKNRRYVILISEKFKISDAEYRTRDIPSDIFVGWIGHELGHVLDYQDRSKLNLIWFGLNYLFSENHIVEAERAADAFAVKQGMEEYILKTKNFILNNADISQNYKNRIQKYYLSPEEIMELVKKRAEKEDQALAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM19</accession>
    <name>A0A5C6ZM19_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Class I SAM-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_08050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="298" mass="34049" checksum="75BE0D6D62F627E8" modified="2019-11-13" version="1">MLKQSHPHAYLEVKDHSVSGESFQLVLNSKWDYLETHPKPDMDTLADYYESEDYISHTDASRNPLEKVYQIVKSVSLKRKLKLINSVSNFKVDAQPSEEKKLLDVGCGTGDFLKTAKDNQWHITGIEPNEKARSIAIDKCGKAILDTDALSKLPPQHFDVITLWHVLEHLPNLQDQLALFVGLLKPKGTLIIAVPNYNSYDAKHYKQFWAAFDVPRHLWHFSQEAINRLLLANNMKVINTKPMVFDAFYVALLSEKYKSGTMNAFKAFWQGLKSNWKATTSSEYSSLIYIAKMNNNAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMF2</accession>
    <name>A0A5C6ZMF2_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Nicotinate phosphoribosyltransferase</fullName>
            <ecNumber evidence="4 8">6.3.4.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">ESY86_05025</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O + nicotinate = ADP + diphosphate + nicotinate beta-D-ribonucleotide + phosphate</text>
            <dbReference type="Rhea" id="RHEA:36163"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32544"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57502"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1.</text>
    </comment>
    <comment type="PTM">
        <text evidence="8">Transiently phosphorylated on a His residue during the reaction cycle. Phosphorylation strongly increases the affinity for substrates and increases the rate of nicotinate D-ribonucleotide production. Dephosphorylation regenerates the low-affinity form of the enzyme, leading to product release.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the NAPRTase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.21" evidence="4 8"/>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00457"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004516">
        <property type="term" value="F:nicotinate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004514">
        <property type="term" value="F:nicotinate-nucleotide diphosphorylase (carboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041525">
        <property type="entry name" value="N/Namide_PRibTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041619">
        <property type="entry name" value="NAPRTase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040727">
        <property type="entry name" value="NAPRTase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007229">
        <property type="entry name" value="Nic_PRibTrfase-Fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006405">
        <property type="entry name" value="Nic_PRibTrfase_pncB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036068">
        <property type="entry name" value="Nicotinate_pribotase-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11098">
        <property type="entry name" value="PTHR11098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04095">
        <property type="entry name" value="NAPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17956">
        <property type="entry name" value="NAPRTase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17767">
        <property type="entry name" value="NAPRTase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000484">
        <property type="entry name" value="NAPRT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51690">
        <property type="entry name" value="SSF51690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01513">
        <property type="entry name" value="NAPRTase_put"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 8 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7 8" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NAPRTase_N" evidence="10">
        <location>
            <begin position="8"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="NAPRTase" evidence="9">
        <location>
            <begin position="150"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="NAPRTase_C" evidence="11">
        <location>
            <begin position="350"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF17767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF17956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TXD90113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="465" mass="52170" checksum="B3DE5F12B1F151DB" modified="2019-11-13" version="1">MNITAAYTDYYQLTMAQVYFGTKPNGRAVFDYYFRSNPFNSGYSIFAGLEDVLNILETLEFTASDISYLKQHGFENDFLEYLKDFRFRGSIFSSKEGDVVFPNRPILQVEANIIEAQIVETLLLNMLNFQTLIATKASRIRRSAKDGILLDMGLRRAHATGGYYASRAAAIGGFDSTSNVKAAEDYNIPSSGTMAHSFIQSYEDELQAFRDFAKMRPVNCVLLIDTYNTLRSGLPNAITVAKEMESNGTQLMGVRLDSGDLAYLSKKTRKLLDDANLDYVKIVVSNQLDEYVIKSLKDQGAPIDIFGVGTNLVTGKPDAALDGVYKLSEYNGDPRIKLSENIIKVSLPSKKQVYRMLDSTGMFYGADAVALFNEAEVAQMEHPFDATKSLNLSSFKQEPLLEKVMEDGKRTTPSRSVSEIADYSKSRLAQLPDEYKRFQNPHIYKIGLSTALKQERDTLVQKHKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMN0</accession>
    <name>A0A5C6ZMN0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0675">Receptor</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Plug" evidence="1">
        <location>
            <begin position="213"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="833" mass="94924" checksum="1D17F6EFFD6567BF" modified="2019-11-13" version="1">MLKIKHYILFSFFVLNTFWVIGQNNTQKIPIINILDEITATHNVTFNYESRLLENITVIPLPKNLSLTNKIKNLEKQTNLIFSKISDVVISITEAITICAYIRDTSQKVLSGATIKGATAYAISKDDGYFEIEVASLSDIITIRFMGFKTIERKAQFFNLNSCEIISMLEEEQVISPVVLNGYLVQGIDKRQDGSTLIDYSKFTLLPGLIESDVLQTVQALPGIISVDETVSNINIRGGSHDQNLMLWDDIKMYQSGHFFGLISSFNPQITQTATVINNGTDASYSDGVSGSIFMESDKKLQSKFEGSFGINLLNADLFADVPLGEKSSVQIAARKSTDDLLRTPTYDTYFDRVTQETEAQNNSSEVSNSNQGFDFYDTSLRWLYQPTDKDIIRLNFILINNNLSFDETATLNGALETRESSVSQNSMAAGLNYKREWNSNLSTTLNIYNTDYKLQAINANILAGQRFLQENSVSETAIKLEALYHQNLWKFMLGYNFVESEVVNLNDIDLPRFVRRDSEVLREHAVFGQTYYENEAKDFSVRSGVRLNYIDEFNELIIEPRLNIRKALGNHFEIEALGEFKHQNVSQIVNFQNDFLGIEKRRWQQTDNDSIPILKSKQASLGILYKNKGWLVDVKGYFKTVAGITTQSQSFTTKYELEKEKGSYDAYGVEVLFRKKFKHLNSWLSYSYINNTYTFETLEDKEFPSNFDITHAFTMGSTFSNTHWNISAGLNYRTGQPTSIPLLGNEVIDDAVNFDTANSSRLQDYMRIDVSALYKFKISNSFRSEIGASVWNLSNRENPINNFYRVNDNNDPIKFSRFSLGITTNAVWRLYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMZ7</accession>
    <name>A0A5C6ZMZ7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acyl-CoA thioesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_01120</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 4-hydroxybenzoyl-CoA thioesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008272">
        <property type="entry name" value="HB-CoA_thioesterase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006684">
        <property type="entry name" value="YbgC/YbaW"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003230">
        <property type="entry name" value="YbgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00051">
        <property type="entry name" value="TIGR00051"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01328">
        <property type="entry name" value="4HBCOA_THIOESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4HBT" evidence="3">
        <location>
            <begin position="22"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD91219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="136" mass="16064" checksum="5A35975DE6DC58C6" modified="2019-11-13" version="1">MSKLRKHDEIQFRVRYGETDQMGVVYHGNYAQYFEMGRTEWLRKFGFSYKQMEADGIMLPVISLTVKFKKPARYDDLIKVKTEVVKKPSARIEFTYEISNEADEILTTGTSELVFMDMVKNRPTRCPKYILDQLPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNE1</accession>
    <name>A0A5C6ZNE1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Mobilization protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_05520</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043766">
        <property type="entry name" value="DUF5712"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18976">
        <property type="entry name" value="DUF5712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="217"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="163"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="343" mass="39287" checksum="5DFA004558998F28" modified="2019-11-13" version="1">MYITITAQKLGGNYSQSSADFVGYLEKENEGLEQRDMEHFFNQYGDETSAEKVVKEIDGNTAKLKKKEPKFYSITVSPSKYELKRLQNSRDDLKTYTRELMKDYVASFNREINGRPITIDDIKYYAKIEHQRTFKGTDFQIKENQPIATKILQLKTDIRNIQEGRAEGNIKKMEKEIAKLERQAPHQQNGKRIVQGMAKDGNQSHIHIIVSRKDASNSVSLSPGSKHKASEVEMHGKKVKRGFDRDKFFDKAEKTFDKTFGYKRNFAETYKARKDFVKNPNLYFAALMKLPANEKALAFKMITKTGLPVIPSIPVSQAQIALRVFKRLRRGAEIAIKSSSIGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNE8</accession>
    <name>A0A5C6ZNE8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Crp/Fnr family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_05575</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="199" mass="23414" checksum="A79E2DEC10EF728F" modified="2019-11-13" version="1">MIDSQTTEHYFDVLFTYVRLLVDIPKIDQHICREYFKPIVVKKDTLLEKEGTVHGYHNFIVKGYMRIFHHDQNDEEITTNINDGPRFFTSYNHFVHKSISNENLHCITDCELLRIKRDDVDITAKLGITQLDYSMKILQYHLEKNKQRTIDLTTLTAEERYLKFMRNSPSILKNVPLKYIASYLGMNPGSLSRIRAQIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNW9</accession>
    <name>A0A5C6ZNW9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Polyphosphate kinase</fullName>
            <ecNumber evidence="6 7">2.7.4.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">ATP-polyphosphate phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Polyphosphoric acid kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ppk1</name>
        <name evidence="6" type="synonym">ppk</name>
        <name evidence="12" type="ORF">ESY86_03315</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>[phosphate](n) + ATP = [phosphate](n+1) + ADP</text>
            <dbReference type="Rhea" id="RHEA:19573"/>
            <dbReference type="Rhea" id="RHEA-COMP:9859"/>
            <dbReference type="Rhea" id="RHEA-COMP:14280"/>
            <dbReference type="ChEBI" id="CHEBI:16838"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="PTM">
        <text evidence="6 7">An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the polyphosphate kinase 1 (PPK1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.1" evidence="6 7"/>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009358">
        <property type="term" value="C:polyphosphate kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008976">
        <property type="term" value="F:polyphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006799">
        <property type="term" value="P:polyphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1840.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00347">
        <property type="entry name" value="Polyphosphate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003414">
        <property type="entry name" value="PP_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041108">
        <property type="entry name" value="PP_kinase_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024953">
        <property type="entry name" value="PP_kinase_middle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036830">
        <property type="entry name" value="PP_kinase_middle_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025200">
        <property type="entry name" value="PPK_C_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025198">
        <property type="entry name" value="PPK_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036832">
        <property type="entry name" value="PPK_N_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30218">
        <property type="entry name" value="PTHR30218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02503">
        <property type="entry name" value="PP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13090">
        <property type="entry name" value="PP_kinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17941">
        <property type="entry name" value="PP_kinase_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13089">
        <property type="entry name" value="PP_kinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015589">
        <property type="entry name" value="PP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140356">
        <property type="entry name" value="SSF140356"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03705">
        <property type="entry name" value="poly_P_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 6 7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PP_kinase_N" evidence="9">
        <location>
            <begin position="9"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="PP_kinase" evidence="8">
        <location>
            <begin position="122"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="PP_kinase_C_1" evidence="11">
        <location>
            <begin position="329"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="domain" description="PP_kinase_C" evidence="10">
        <location>
            <begin position="502"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphohistidine intermediate" evidence="6">
        <location>
            <position position="433"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="373"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="403"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="466"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="562"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="590"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF17941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TXD90410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="683" mass="78970" checksum="555D6F0D5C1DA746" modified="2019-11-13" version="1">MIKAQKNDYVNRELSWLQFNGRVLQEAADEDVPLIERLRFLGIFSNNLDEFFKVRYATIKRIDEAGKGGKSELGIKASDLLVLITDIVIKQQSKSLDILSNIQNKLEKKNIFVIKETELDAEQQIFIKNYFIEHVSPALVTIILNNKVELPMLEDISAYLAVKMELKDGDRQFALIEIPKSMDRFVVLPRKDDKDYIIILDDLLRYCLDDIFNIFNYSEISAHMIKITRDGELDFDSDLSKSFIEKISASVKDRQIGEPVRFVYDQTIDGVTLEYLMSVMGIDSKDSIIPGGRYHNRRDYMGFPSLGRTDLLYDKIVPLKVKGLSLETSIFKTISERDYMLHTPYQTFSYIVKFLREAALDPKVKTIKITIYRLAQISHVASSLINAAKNGKSVTVAIELRARFDEQANIDYAQQMQDEGITMLFGVTGLKVHCKLCVIEREEAHHLKRYGFISTGNFNESTARLYTDFTLFTSNQKILKDINKVFSFFEINYLIYRYKHIITSPHYTKSKIFLLIDQEIRNVKLGRPAFIKLKLNSISSYKMIDKLYEASRAGVKIQMIVRGICCLIPGVKGMSENIEVISIIDKFLEHTRLYVFCNNDDPKIYISSADWMSRNIENRVEVSCPIYQENLKQELLDTFEICWSDNVKSRIIDGSPDNNYKAQSLPRVRSQFALYDYFKNKLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZQQ6</accession>
    <name>A0A5C6ZQQ6_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 4">Thymidylate synthase</fullName>
            <shortName evidence="4">TS</shortName>
            <shortName evidence="4">TSase</shortName>
            <ecNumber evidence="1 4">2.1.1.45</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">thyA</name>
        <name evidence="6" type="ORF">ESY86_02545</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the reductive methylation of 2'-deoxyuridine-5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + dUMP = 7,8-dihydrofolate + dTMP</text>
            <dbReference type="Rhea" id="RHEA:12104"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57451"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <dbReference type="EC" id="2.1.1.45"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Pyrimidine metabolism; dTTP biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the thymidylate synthase family. Bacterial-type ThyA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.45" evidence="1 4"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00575"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004799">
        <property type="term" value="F:thymidylate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006231">
        <property type="term" value="P:dTMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006235">
        <property type="term" value="P:dTTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00351">
        <property type="entry name" value="TS_Pyrimidine_HMase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.572.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00008">
        <property type="entry name" value="Thymidy_synth_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045097">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023451">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036926">
        <property type="entry name" value="Thymidate_synth/dCMP_Mease_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000398">
        <property type="entry name" value="Thymidylate_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11548">
        <property type="entry name" value="PTHR11548"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00303">
        <property type="entry name" value="Thymidylat_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00108">
        <property type="entry name" value="THYMDSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55831">
        <property type="entry name" value="SSF55831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03284">
        <property type="entry name" value="thym_sym"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thymidylat_synt" evidence="5">
        <location>
            <begin position="2"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="156"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="21"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="123"/>
            <end position="124"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="185"/>
            <end position="188"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="226"/>
            <end position="228"/>
        </location>
        <ligand>
            <name>dUMP</name>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="282"/>
        </location>
        <ligand>
            <name>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD90963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="283" mass="32375" checksum="F18808E533934EDC" modified="2019-11-13" version="1">MKQYHDLVKHVLENGTQKGDRTGTGTKSVFGYQMRFDLSEGFPMVTTKKLHLKSIVYELLWFLKGDTNINYLTENGVRIWNAWADKNGDLGPVYGQQWRNWNSDEIDQIKEVIDTLKTNPNSRRMLVSAWNPSVLPDTSKSFDENVANGKAALPPCHAFFQFYVSPPDQSKGEKKAKLSLQLYQRSADIFLGVPFNIASYALFSMMVAQVCGYEAGEFIHTFGDAHIYSNHIEQMELQISRDPKPLPKMLINPEIKDIFDFKFEDFSLENYDPHPHIKGKVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZR13</accession>
    <name>A0A5C6ZR13_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methyltransferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_00860</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022852686" evidence="1">
        <location>
            <begin position="27"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="Methyltranfer_dom" evidence="2">
        <location>
            <begin position="87"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD91333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="244" mass="27689" checksum="EA64605C601FCA85" modified="2019-11-13" version="1">MLQRVKNFKNFIIVLLPLIVLQLSCAQDAKPSEAYVFKNGNPNGIGKWYMGREIAHVMGFQGIDWLERTARETEENTSKLINNMNIKTGDTIADIGAGSGFHVFKMAPLAKNGLVYAVDIQEQMLKAMEARIYRDDVKNVSLIMGNEKSVNLPENSVDKLLMVDVYHEFNDPKEMMASIEKALRADGKIYLIEYRAEDSAVPIKKVHKMSEAQAVKEFEAAGFVLEENMDNLPWQHCMVFVKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6Z9Z4</accession>
    <name>A0A5C6Z9Z4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20395</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000070">
        <property type="protein sequence ID" value="TXD86313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039060">
        <property type="entry name" value="Antitox_HigA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40455">
        <property type="entry name" value="PTHR40455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="61"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="122" mass="14097" checksum="A57FDFB81718C2E0" modified="2019-11-13" version="1">MNVKPIKSDKDYRNALERLEVIFDAPIDTKEGDEAEILSLVIENYENERYPIEAPDPIEAIKIRMEELNMRQKDLVGIIGGKSRVSEVLNRKKRLTVDMIRELERILQISASVLVNNYKLAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAD8</accession>
    <name>A0A5C6ZAD8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000065">
        <property type="protein sequence ID" value="TXD86384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022661521" evidence="1">
        <location>
            <begin position="18"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="184" mass="20920" checksum="53C5DB7376BAFFFD" modified="2019-11-13" version="1">MRKILVLLLLISSFANGQKLIKKTEENKVKLDNSMKIFSSNAGYCKIYKLTENIFALHNGYMEGNKITYVDKNALDEIIKASEMINDADFGDKVELVSIEMDIEKKKIIGTAYVFTIYKNETTTDLSDLTLTEIRELMETADLNSVESDGVKVVDKVKTITSEKAHSFMTLTKKELEILIELKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAH5</accession>
    <name>A0A5C6ZAH5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carbohydrate binding family 9 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_19705</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000046">
        <property type="protein sequence ID" value="TXD86622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010502">
        <property type="entry name" value="Carb-bd_dom_fam9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045670">
        <property type="entry name" value="DUF5916"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06452">
        <property type="entry name" value="CBM9_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19313">
        <property type="entry name" value="DUF5916"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carb-bd_dom_fam9" evidence="1">
        <location>
            <begin position="37"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5916" evidence="2">
        <location>
            <begin position="230"/>
            <end position="802"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="806" mass="93346" checksum="63A355DBD3420A89" modified="2019-11-13" version="1">MLRYIFTTMLCSAITMSYGQNKIKQYNVIRTSDVPKIDGKPFEKIWELAEVGNNFIMLQPENGTAENEQQKTLIKIMYDDNAMYVAAYLYDNEPNKIAAQFSQRDQINVQSDIFSFWINTYNNQIDQTRFYITAAGAIADSKSTNGGDDFSYNVIFDARSSRDEKGWYVEMEIPYQALRFAKSSVQDWSFNAYRKINRLNQSFTFSFIDIKQGNEAQYDAVLRGIQNINPPSRLSLFPYLSTQSVQFKNTNKTQFNAGLDVKYGLSDAFTLDATLIPDFGQVAFDNVELNLSPFEQVFEERRPFFTEGTDLFSKGNLFFSRRIGQQPFGFSSVYNQVDENEILISNPTQTQLINAVKITGRSKSKIGIGLLNAITKKMTATITDTLNLTNRKIITESLTNFNIFVIDKQYGANSSFYFSNANTLRSGSFTDANVTAFGIDHYDKENIYNYGANVKMSNRFLNDSTSYGFSYSARWQKVEGKWRYGISHDYIEKSYNPNDLGLQFESNINTTYISGSYNQFTPKGKFNNYTINYNLYHSRTNQPNTHNFTQVSLNPNFQTKNLWQGGGFITAFTREYDFFESRISLVPVLYQPKIVYGSYITTDTRKRVSLFANINAENRINNPEFRIDFRLRPSFRITDKLFIRYQWFWQKRDNRLSFVALNGEQTILSSRDTRTIENSIETVYNIDNTKAINLRLRNFWSNAIFSDNLEILKSDGSTIAFSEPNSFEPNADFNVWNFDCSFEWQFAPASSLIVFYRNTLSNFQNNPNQSYFNSLDALFQNSLVHTLSLRLTYFFDVNRLKKRELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAI7</accession>
    <name>A0A5C6ZAI7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP-binding cassette domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000044">
        <property type="protein sequence ID" value="TXD86654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="1">
        <location>
            <begin position="1"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="126" mass="14058" checksum="43B046979D197DE3" modified="2019-11-13" version="1">MVFQKPHFIKSLNVIENIESKLYFSKAGVETKKMETILDALEMTPFKHTKVAELSEGQKQRLSIAIALISRPSLILANEPTSALDDSNCAQVLSLLHNTAEVVGAHLLVITHDQRVKPYFSNTLEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAR5</accession>
    <name>A0A5C6ZAR5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF4382 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_18140</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000030">
        <property type="protein sequence ID" value="TXD87055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025491">
        <property type="entry name" value="DUF4382"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14321">
        <property type="entry name" value="DUF4382"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022661868" evidence="1">
        <location>
            <begin position="36"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4382" evidence="2">
        <location>
            <begin position="48"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="198" mass="21967" checksum="28C7F1E4BEE06BD6" modified="2019-11-13" version="1">MMIYNDKSPQIMNFKTSLKFLFTAACILLMFTSCSKDELDNYGNETAITVKLKGAENNLQNLMIDIKDVQLLIGADANTPGAWMSLDLLSSGVYNVTQLNNDNELILVDGMLIPSGEVQQIKLLLGNDNAIIVHNQSRPLGSDAEELASSNIVAKRLASNKNYEFTLEFESDNSIIVTADDSINFVPKMNTLIRHLQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZB88</accession>
    <name>A0A5C6ZB88_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_20410</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000071">
        <property type="protein sequence ID" value="TXD86299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="153" mass="17978" checksum="A80BA0CFDECEDD42" modified="2019-11-13" version="1">MEKIILSFMFIFCVYFGNSQNKDVNTYEIKYLKTFNFESGGTFSADHTYTKFIELNKSIFDVTTNLESQNTLVEGQNKLVESEDDDTVFYFSPTGKNISLVYKDYLKQELFSKNEVSFKYFVVQDSLNIFNWETFENQKNILGYSCQLAKMNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBA9</accession>
    <name>A0A5C6ZBA9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000106">
        <property type="protein sequence ID" value="TXD85965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD85965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="155" mass="17629" checksum="7BA2EBFEDAA5CA00" modified="2019-11-13" version="1">MIKLTKPLTIPFIALGIVLSLVFGVEYNCQGEEMFPIYYGSPFVFKEKSLGSSMEYFYSISGILLNVAIWSVIIALLRLAILKTLDLKSKSRILTKIYKGTVIILVVFSALNIGISYIGIGQGFKKGLNYWYMDLDKEAKDWGMECEGEWKFWIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBD1</accession>
    <name>A0A5C6ZBD1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">TerB family tellurite resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19515</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000041">
        <property type="protein sequence ID" value="TXD86729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3680.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029024">
        <property type="entry name" value="TerB-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158682">
        <property type="entry name" value="SSF158682"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="143" mass="16484" checksum="118FA1546C4946ED" modified="2019-11-13" version="1">MSFSDLFDSGFKRRNEDHFASIVRVAMDDGIISDDERAFLERLAKRLDISEGDFKLILKNYQSHPINPPTSYDRRLERLYDLSRMVHVDHIQGEKEELVLQKIAIGLGFSTENVKYIVNKALTLVSNGVDLDTFTAEMKTMNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBP3</accession>
    <name>A0A5C6ZBP3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_17890</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000028">
        <property type="protein sequence ID" value="TXD87186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022979130" evidence="2">
        <location>
            <begin position="21"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="95" mass="10255" checksum="636FED2357914E77" modified="2019-11-13" version="1">MKKSLYLATFLSLLSTTLFAQIGGIEDSVDDVANTIRSIFPIILGVIFLVGFLFNAGHFFGENADLKKGITRVLVFVLIAGAVVGIFTYLISIVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBR2</accession>
    <name>A0A5C6ZBR2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF58 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000030">
        <property type="protein sequence ID" value="TXD87053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002881">
        <property type="entry name" value="DUF58"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01882">
        <property type="entry name" value="DUF58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="1">
        <location>
            <begin position="78"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="288" mass="33406" checksum="0CC2DDBA536521BE" modified="2019-11-13" version="1">MDTKELLKKVRKIEIKTRRLSDHIFGGEYHSTFKGRGMTFSEVRQYQFGDDVRNIDWNVTARYSEPFIKVFEEERELTMMLVVDISGSKLFGTKEQFKDEIITEIAATLAFSATQNNDKIGLILFSDEIELYIPPKKGRSHVLRIIRELLEFKPKSKKTDLAMALKFLSNVMKKKAIVFVLSDFIADDYQHTLKIAAKRHDITGIRVYDRHEESIPSLGMVQMEDEETGELVLVNTSSKTVRNNYSKFYNEKVSYFKESFNKSGAGSIDCRVDESYVRKLLGYFKRRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBY0</accession>
    <name>A0A5C6ZBY0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">IS1634 family transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20625</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000095">
        <property type="protein sequence ID" value="TXD86082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1" evidence="1">
        <location>
            <begin position="169"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="503" mass="57877" checksum="B12095089BD94611" modified="2019-11-13" version="1">MFVRKKQNKSGVISVQVVDKSTGRYRMLRTIGSSSIGSEVERLVGEAKQWIKKQTGSQELDFTDYAHHTKLVLQGIEQIAVHGPALLLGKIFDEVGFGQIKQDLFRQLVLARLCYPASKLKTTDYLSKYQFLDIDVQVVYRYLDKLYKEQKELVQQISYQHTLRILDNKINVVFYDVTTVYFEAESEDDLRRTGFSKDGKHQHPQIVLGLLVSKGGYPLAYDIFKGNQFEGHTMLPIINAFQAKYNLDKLVVVADAGLLSKENIQLLEQGGYGYILGARIKSVNNELKEKILALKLANAESQTIEIDPESKLIVSYSQVRARKDAHNRKRGLDKLEKHIKSGKLTKASINNRGYNKYLHIENEIKISIRPEKIEEDKKWDGLKGYITNTNLTKEDILENYKDLWQIEKAFRVAKSDLEIRPIYHRVQRRIEAHICIAFVAYKIYKELERQLKTKGSTLSPEKAIDIAKTIYAVKVKHPVTKEITYTTIINSEQQQNLAKLFDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC63</accession>
    <name>A0A5C6ZC63_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carboxymuconolactone decarboxylase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000030">
        <property type="protein sequence ID" value="TXD87079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003779">
        <property type="entry name" value="CMD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02627">
        <property type="entry name" value="CMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="SSF69118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMD" evidence="1">
        <location>
            <begin position="40"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="196" mass="21907" checksum="6E3B38ADC7680455" modified="2019-11-13" version="1">MALVTPLSAEHDLETKALAEFFNETLGFCPNSVLTMQRRPAISKAFINLNKAVMANEGRVTSALKRMIAWVSSNATGCRYCQAHAIRAAERYAAEQEQLDNIWEYRTHSAFSEAERVALDFSLAASQVPNAVNADIKARLYKHWDEGEIVEMLGVISLFGYLNRWNDSMGTSLEEAAVESAHQYLGKHGWERGKHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC95</accession>
    <name>A0A5C6ZC95_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19945</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000052">
        <property type="protein sequence ID" value="TXD86553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000801">
        <property type="entry name" value="Esterase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00756">
        <property type="entry name" value="Esterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="361"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="499" mass="57077" checksum="D338C1290F9C7909" modified="2019-11-13" version="1">MLKNPKIKTIMKTIFITFALLLFSFFLKAQNNENITIGKKEVITSKVLNENRTLWIYTPKITSQSPNPDKRYPVLYLLDGSAHFYSTVGIIQQHSQANGNGTLPEMIVVAIENTNRVRDFVPSNDLDNPNPFIEFLSSELIPHIDKNYKTAPYKMLVGHSLGGLTVIDILTNFTELFNAHIAIEPSMWYDNEKNLTNTISRFPKQNMNGKRLFIGTANTLPKGMEFSQLKNDKSFETQHIRSIFKLDKFLKANTNGLIYGSKYYENETHNTVPLISEYDGLRFIFDFYLLDATEKDFTDSTDLIASKLKIHYANVTEKMGYMNAAPEAFINYFAYEALGKQHYNKAKALFELNIEWYPESSNVYDSYADYYLAQKDTTNAISNYQKALEINGNAETRSKLDSLTAKVILKPETIDLQKYAGVYVIETYNISIVLEIRDNKLIAKVPGQEDDEFEFQSEHIFTVKGKQGYKVTFEMDGDKPKGFTSVQPNGTFQATFKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC99</accession>
    <name>A0A5C6ZC99_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19795</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000048">
        <property type="protein sequence ID" value="TXD86595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022664822" evidence="1">
        <location>
            <begin position="20"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="204" mass="22862" checksum="7F8AABB5C392F88B" modified="2019-11-13" version="1">MKQIILVIVVALTILNCKAQSPVLEMGVDALNDAPDNSYYKDVNNVLNDFEGTWLYTNGNTSLKITLVKYLQLYNGKYYEDLLIGGYQYIENGIEIVNTLDDANNPNLGISASIDGNLILKDCNYHPVNDCVDGEKSLRLGIDDPNSDKHWGILRLFKRTINGQDALKIIIEMTHVTDGEDPEDGDLPSPSIPWHIRNINLIKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCD3</accession>
    <name>A0A5C6ZCD3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17830</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000028">
        <property type="protein sequence ID" value="TXD87174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="327" mass="37172" checksum="8E55B4BACBF53EC7" modified="2019-11-13" version="1">MKKGYKILIITALFISGLSFTAWNVFNYYWRTQGTVNTFSTFTEPEALSFSKIKWVEDSFGTFKTDISAFFIKVELNGVDDSFYMQFDTGTSQTLFYGKTLHALKAKHPSFEPVESQSGNYWLKSPVLKIGDLNFGARDLLVKADLGSEEIDPSFTIIGTIGFDAIVGRKLILDFKNNQLTITNKDINKLNYIFKPLEGASLDRFPILIPAEVDGEDVQLLYDTGSSMFPLIVDNQKLLHIENAGRTDTLCCTTSWGKSYDFYRRKLNTDIKIGNLVEKQPYVYSSKSMDQYDYFPNWLTMGIAGNHMFIDKILLIDTQNNIFGICD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCD6</accession>
    <name>A0A5C6ZCD6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP-binding cassette domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19635</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000044">
        <property type="protein sequence ID" value="TXD86655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="1">
        <location>
            <begin position="22"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="78" mass="8546" checksum="98CAD2B43987EEFE" modified="2019-11-13" version="1">MLSTHKLHFSYPRGPSFDLPDITLADQKHLLILGKSGVGKTTLLHLLGLLLRLNSGSITINGKELSVLGERQKGFVPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD39</accession>
    <name>A0A5C6ZD39_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8 10">Thymidine kinase</fullName>
            <ecNumber evidence="2 8 10">2.7.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">tdk</name>
        <name evidence="12" type="ORF">ESY86_18245</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8 10">
            <text>ATP + thymidine = ADP + dTMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19129"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17748"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.21"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 11">Belongs to the thymidine kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.21" evidence="2 8 10"/>
    <dbReference type="EMBL" id="VORO01000030">
        <property type="protein sequence ID" value="TXD87074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004797">
        <property type="term" value="F:thymidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00124">
        <property type="entry name" value="Thymidine_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001267">
        <property type="entry name" value="Thymidine_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11441">
        <property type="entry name" value="PTHR11441"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00265">
        <property type="entry name" value="TK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF035805">
        <property type="entry name" value="TK_cell"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 10" id="KW-0237">DNA synthesis</keyword>
    <keyword evidence="6 8 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 8 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 10" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="8 9">
        <location>
            <position position="94"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="21"/>
            <end position="28"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="93"/>
            <end position="96"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR035805-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TXD87074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="215" mass="24044" checksum="A625D843D19856FF" modified="2019-11-13" version="1">MFLENTGNHKEQFGWIEVICGSMFSGKTEELIRRLKRAQFARQKVEIFKPTVDIRYDQDMVISHDANQIRSTPVPAAANIPILADGCDVVGIDEAQFFDDEIVRVCNDLANKGVRVVVAGLDMDFKGNPFGPMPNLMATAEYVTKVHAICTRTGNLAQYSYRKAASEALVLLGEVDEYEPLSRAAFYKAMTRDKVRQMKVNDAETISSKDKKTNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDM7</accession>
    <name>A0A5C6ZDM7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Efflux RND transporter periplasmic adaptor subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_14580</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HlyD_D23" evidence="3">
        <location>
            <begin position="47"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="109"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="425" mass="46302" checksum="08262036077B76F3" modified="2019-11-13" version="1">MSKKTKIIIGVIVVLLLVLVIAAKMDLFGKKGNFKEVDVKKVTLIDITETVSATGKIQPEVEVKISSEVSGEIIELPFKEGQQVNKDELLVKVNPDLIQSAVNRSQASYQNVKSGLAQAEASLKEAKSNYDRNKILFEKGVISKADWDRSIAAYETAEAAKNSAYYGVRSAAATVNEAQDNLSRTTIYAPMSGTISLLSVELGERVVGTQQMAGTEILRVANLKDMEVEVDVNENDIVKVQIGDTTLVEVDAYLKKEFKGIVTQIANSAGQALTADQVTNFRVKVKILKESYKDLTEGKPEHYSPFRPGMTATVDIMTAQRKNAVAVPISSIVIKTDTSSVKKSFEKMAADTVEPENEERFECVFINDNGTAKLKVVKTGIQDDTNIEIVSGLAEGDQIITGPYNVVSKTLNAGDKVEVISDKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDX8</accession>
    <name>A0A5C6ZDX8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF2461 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_15900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012808">
        <property type="entry name" value="CHP02453"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015996">
        <property type="entry name" value="UCP028451"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36452">
        <property type="entry name" value="PTHR36452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09365">
        <property type="entry name" value="DUF2461"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028451">
        <property type="entry name" value="UCP028451"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02453">
        <property type="entry name" value="TIGR02453"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="223" mass="25875" checksum="2C04D81FF6184DA4" modified="2019-11-13" version="1">MVDKAYIFRFLRDLGNNNSKEWMDDNRAGYHTMKERWLEEIDLILKRLAQYDTHYETVNPKKTISRINNNRRFHPEKPTYKQNLTCSPAGKKEKGKSTFFISIGPDQSFIGGGLYHPSKEHLEKIRAAIDYNGDTLKTILNEKQFKSFYGGLNTYDDKLVTSPQNYDKNHAHIDLINHKSFTATIDLTEAQVTSAHFVDLVEEAFLKYKPLDDYLVKAITMDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE07</accession>
    <name>A0A5C6ZE07_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L34</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpmH</name>
        <name evidence="7" type="ORF">ESY86_17030</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the bacterial ribosomal protein bL34 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000025">
        <property type="protein sequence ID" value="TXD87375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00391">
        <property type="entry name" value="Ribosomal_L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000271">
        <property type="entry name" value="Ribosomal_L34"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020939">
        <property type="entry name" value="Ribosomal_L34_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14503">
        <property type="entry name" value="PTHR14503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00468">
        <property type="entry name" value="Ribosomal_L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01030">
        <property type="entry name" value="rpmH_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00784">
        <property type="entry name" value="RIBOSOMAL_L34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="29"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD87375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="53" mass="6344" checksum="59C236F276339F21" modified="2019-11-13" version="1">MPKRTFQPSKRKRRNKHGFRERMASVNGRKVLARRRAKGRKKVSVSSEVRHKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE40</accession>
    <name>A0A5C6ZE40_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_14195</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="135" mass="15513" checksum="E85E18526C362578" modified="2019-11-13" version="1">MTSQYVFIDLDAPNGYWFSIFADNEVLNKSIRIERILSDIPLEEGVYTFGNNENGVLNANYGFVGDIVWNDDGTGYQPVFNYNTTTQTAGELNIIKLDEEEQILSGTFWFDCVDSEGNVIEIRDGRFDLKYKNYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZED4</accession>
    <name>A0A5C6ZED4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">SsrA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_16675</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000023">
        <property type="protein sequence ID" value="TXD87528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="53" mass="6239" checksum="D4D378AFED383ABE" modified="2019-11-13" version="1">MRPMKHNFFKLLAKLNKLVLPSYSKQELDLSKASKFQMALIGWRVFVTKRALD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEJ4</accession>
    <name>A0A5C6ZEJ4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17935</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000028">
        <property type="protein sequence ID" value="TXD87195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041657">
        <property type="entry name" value="HTH_17"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12728">
        <property type="entry name" value="HTH_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_17" evidence="1">
        <location>
            <begin position="37"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="94" mass="10629" checksum="32BC7C429E347682" modified="2019-11-13" version="1">MPTSIITTDDLREFKMELLDDIKNLLAKQSKGKLKKYLKSSEVMDLLQVSPGTLQNLRINGTLPYTKVGGIIYYDTEEIQNVMTANRVQHGLNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEN3</accession>
    <name>A0A5C6ZEN3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Stage II sporulation protein M</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15930</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000021">
        <property type="protein sequence ID" value="TXD87649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002798">
        <property type="entry name" value="SpoIIM-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01944">
        <property type="entry name" value="SpoIIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="156"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="187"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="215"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="262"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="287"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="325" mass="36851" checksum="3AFADA46E5275521" modified="2019-11-13" version="1">MREVAFIKQNKEKWLNFEQAIFGKTLKNPDELASLYIHLVNDLSYAQTYYPKSKTILYLNNLAAKAFQKIYKTKREDTNRFVHFFKVEVPMIIYEYRRYVLYAFIIFLSFVAIGALSAANDASFVRLILGDSYVNMSLENIEAGDPVAVYKSGSNWGSFIGITLNNLYVGIKAFIFGIFVGLGTAMIMLYNGIMIGAFQYFFYKEGVLWESVRGIWIHGAMEIFAIVIEGAAGLILGASILFPKTYSRLTSFKMGVKNGVKILISTFPFTIAAGFLEGYVTRYSNSMPNWLSVGIIVITLSLISFYYLIYPFILNAKLKQTYAII</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEU9</accession>
    <name>A0A5C6ZEU9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17645</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000027">
        <property type="protein sequence ID" value="TXD87258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01022">
        <property type="entry name" value="HTH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="8"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="109" mass="12158" checksum="B8FE59B2B83B94F0" modified="2019-11-13" version="1">MGLTKTAIFSDTQNEISVFAKVIGHPARVAILEQLFKIDSCICGDFVSEIGLAQATISQHLRELKQMGLIKGTIEGTSVCYCIHRENWTKMKKVMTQFLDQDLSEDSCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF53</accession>
    <name>A0A5C6ZF53_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CAP domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_17125</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000025">
        <property type="protein sequence ID" value="TXD87391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="SSF55797"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022830584" evidence="1">
        <location>
            <begin position="23"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="SCP" evidence="2">
        <location>
            <begin position="49"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="164" mass="18455" checksum="92D1708F0E509811" modified="2019-11-13" version="1">MKPTKFLPVMALVAILSFSCSTETVSNEIIDDLELQSPPSAKEIEIEILELINQHRIALGLNALNSNATIKSVAHSHTDYMVEVNNMSHDYFYQRRNSLIVNVAAQEVSENVAYAYSSAHSVVQAWLRSEGHKANIEGDFTDFDVSAEQNTQGKWYFTNIFIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF73</accession>
    <name>A0A5C6ZF73_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Microtubule-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_12020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="424"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="97"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="184"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="447" mass="50496" checksum="82316AF02E7CAFC2" modified="2019-11-13" version="1">MSNDFDLLETNSNEKSEKVDVNWGKAIDTMKSKLAQEDDPESRQKILNATLDDVVHMAEKDRSTLLDAIKDLTDYQDEVGIIFEKFSSLNANEQKIIDDAVKRLERSKVELEDAEAKPDSWWNNLWGRKSKIKEAQQDLQTAQKDRDAADNKAKAMFQTRIESADVQTLLSELSYKSQAAVTRLKNREVEIKEVEDKLQTAIVEATKNHIKSLEKKKEVEAKLEEKYAALKQARQALEEIVDKQSANYAEAIGKVTTIEQEVEELEGLKNAYTTLAASKDSFVHKHNLTIKVLTSLRSNLQTHRAKLKSDTEERLKYYDGYVVALKARTDQEFAAILEHLGVKTDEHIGETLASMHTASAKARQEMMDNIPVHEKVMQGVYSSYAEALQEIRAKDLDIQKNFSERYGIDMKEIFEDYYKADAAAPTGDDAKPAASSKPKAGADDLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFC7</accession>
    <name>A0A5C6ZFC7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_16955</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000024">
        <property type="protein sequence ID" value="TXD87468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039060">
        <property type="entry name" value="Antitox_HigA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40455">
        <property type="entry name" value="PTHR40455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="61"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="118" mass="13880" checksum="7196C359B8169AD4" modified="2019-11-13" version="1">MEIKPIRNEADYQDVLKRLELIFDAKRGTEEGDELEILAMVINNYENDNFPIEMPDPISAIKFRMEQLGLKQKDLVEMIGFKSRVSEIMNKKRKLTLDMIRKLNANLHIPTEVLIQEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFJ0</accession>
    <name>A0A5C6ZFJ0_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6377 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_12805</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045957">
        <property type="entry name" value="DUF6377"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19904">
        <property type="entry name" value="DUF6377"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="300"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6377" evidence="2">
        <location>
            <begin position="227"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="527" mass="61478" checksum="0CB9C71C8E95809C" modified="2019-11-13" version="1">MQRALDSSIIYDQNKRHSINLLKTQLSKINPQQLEEKFNMYNRLFDEYKVFKSDSAYFYSLKAKETASKLNDSSLINKGYLNLADIAISVGMYKEALDYLENINIETVRAIDKPMYFGLYGRCYSDMAEYSGLLDFSQKYNEMARFYREKTLKLTEEGSFFNVFMAAFNEYRSGGEDSAIITLKTLLKRDLGLGELGLTNYVLGEIYQAKDKLDLAEYHYAQAAVADIRNSTKESLAIIKLSELLFKRNELEFASRLIQKAFEDAQFYGAQQRKLQVGAILPLIDEEIVKGVESEKRRLYIQYIGAIAFLLISILFTSIIFFQYKKLQRTRFIVSKAHNDLKQTHEQLMMVNEELKGRNDEIVMANARLFESNKIKEEYLGLFFTEYDNIFEKFNSLTLEIKKNLSNEDYKKAIYNISRYNLKKEKEKLLHNFDTAFIKLFPNFINEFNNLMTEGNKVNLKSNQILNKDLRIFALLRLGVKHNEKIAQILGYSVNSIYAYKSKIRNKSYLKNELFDEQLNVNTTIEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFL1</accession>
    <name>A0A5C6ZFL1_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosomal silencing factor RsfS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2 3" type="primary">rsfS</name>
        <name evidence="3" type="ORF">ESY86_15105</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Interacts with ribosomal protein L14 (rplN).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the Iojap/RsfS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042256">
        <property type="term" value="P:mature ribosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090071">
        <property type="term" value="P:negative regulation of ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01477">
        <property type="entry name" value="Iojap_RsfS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004394">
        <property type="entry name" value="Iojap/RsfS/C7orf30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21043">
        <property type="entry name" value="PTHR21043"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00090">
        <property type="entry name" value="rsfS_iojap_ybeB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="2" id="KW-0810">Translation regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="125" mass="14253" checksum="4D3AC242E83369B0" modified="2019-11-13" version="1">MAKKNISPDQLITTIIAGIEDVKGKEITILDLREIENTVCDYFIICEGSSNTQVNAIVNSIQKKVSKELKDNPWHVEGSDNAEWVLMDYVNVVVHVFQKQIRTYYDIESLWGDAKTTVIESSYQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFN2</accession>
    <name>A0A5C6ZFN2_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">3,4-dihydroxy-2-butanone 4-phosphate synthase</fullName>
            <shortName evidence="7">DHBP synthase</shortName>
            <ecNumber evidence="7">4.1.99.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">ribB</name>
        <name evidence="9" type="ORF">ESY86_11390</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>D-ribulose 5-phosphate = (2S)-2-hydroxy-3-oxobutyl phosphate + formate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18457"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:58830"/>
            <dbReference type="EC" id="4.1.99.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="7">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="7">Binds 2 divalent metal cations per subunit. Magnesium or manganese.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 7">Cofactor biosynthesis; riboflavin biosynthesis; 2-hydroxy-3-oxobutyl phosphate from D-ribulose 5-phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the DHBP synthase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the N-terminal section; belongs to the DHBP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.12" evidence="7"/>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00275">
        <property type="reaction ID" value="UER00399"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008686">
        <property type="term" value="F:3,4-dihydroxy-2-butanone-4-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00180">
        <property type="entry name" value="RibB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000422">
        <property type="entry name" value="DHBP_synthase_RibB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032677">
        <property type="entry name" value="GTP_cyclohydro_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036144">
        <property type="entry name" value="RibA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00926">
        <property type="entry name" value="DHBP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00925">
        <property type="entry name" value="GTP_cyclohydro2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142695">
        <property type="entry name" value="SSF142695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="SSF55821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00506">
        <property type="entry name" value="ribB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0464">Manganese</keyword>
    <keyword evidence="6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0686">Riboflavin biosynthesis</keyword>
    <feature type="domain" description="GTP_cyclohydro2" evidence="8">
        <location>
            <begin position="223"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="D-ribulose 5-phosphate binding" evidence="7">
        <location>
            <begin position="38"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="D-ribulose 5-phosphate binding" evidence="7">
        <location>
            <begin position="152"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="39"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>D-ribulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="site" description="Essential for catalytic activity" evidence="7">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <feature type="site" description="Essential for catalytic activity" evidence="7">
        <location>
            <position position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD88834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="384" mass="42718" checksum="CEAA7E9C81F458FD" modified="2019-11-13" version="1">MSTSIENRTSKVQLNSISEAIEDIKKGKVIIVVDDENRENEGDFIAAAETVTPEMINFMAKHGRGLICAPLTEDRCDELDLTMMVQNNTVLHHTQFTVSVDLIGHGCTTGISVHDRSKTIKSLIEADTKPNDLGRPGHIFPLKAKNGGVLRRTGHTEAAVDLARLAGFQPAGILVEILNEDGTMARLPQLIEVAKKFDLKIITIEDLVAYRMEHDSLIIKKEDFNIETRFGNFRLRAYQQTTNDQIHIALTMGTWPREEAVLTRVNATLVNNDILGTLTNNADEKLDDMFRVITSEGKGAILFINQQSQSMNLLKRLSILKESQVVGEVIKAPSIEMDSKDFGIGAQILHDLNIHKLKLISNSQQTKRVGMIGYGLEIVEYVGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFS5</accession>
    <name>A0A5C6ZFS5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">LLM class flavin-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_10720</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">To bacterial alkanal monooxygenase alpha and beta chains.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019949">
        <property type="entry name" value="Luciferase_OxRdatse_group-1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="SSF51679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03558">
        <property type="entry name" value="oxido_grp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bac_luciferase" evidence="2">
        <location>
            <begin position="20"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="335" mass="36810" checksum="7EE6967AF61CDEAB" modified="2019-11-13" version="1">MKIQPTLYSILDLALVSEGHTLKQTYTNVLELAQHAEASGYTRYWLAEHHNAPNIGSSATSILIGYVAEGTKTLRIGSGGIMLPNHSPLIVAEQFGTLASLYPNRIDLGLGRAPGTDRETAQAIRSDFMQAAHSFPKELDKIETYFSAENASSKVRATVAEGVDVPIYILGSSTDSAHLAAKKGLPYAFASHFATTHLMEAIGIYRDEFQASNELQTPYVMAGVNIIVADTDEEAERLSTSLIRMIVGIFTGKRDYVQAPTAMTDELKEIMQHPQVHQMLKYSFIGSKATVKAQVKAFMAKTQADELIAVTNIYDGQERIRSYELFAEIMKELNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFT0</accession>
    <name>A0A5C6ZFT0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">30S ribosomal protein THX</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_12260</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bTHX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030826">
        <property type="entry name" value="Ribo_THX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031414">
        <property type="entry name" value="Thx"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17070">
        <property type="entry name" value="Thx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04560">
        <property type="entry name" value="ribo_THX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD88511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="41" mass="4775" checksum="78C5ED654216EBDE" modified="2019-11-13" version="1">MGKGDKKTRRGKINRGTFGVRRPRIKKRPKPEDKINPNKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFV2</accession>
    <name>A0A5C6ZFV2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="68" mass="7572" checksum="AE683177F1530950" modified="2019-11-13" version="1">MVTNYTKSIQAAHVACFLLCVFCCLLPVVCCLFSVARSLFSVLCFLFSVFCCLLPVVCFLLSVFCFPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFV5</accession>
    <name>A0A5C6ZFV5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Molybdopterin oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_14360</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NrfD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005614">
        <property type="entry name" value="NrfD_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03916">
        <property type="entry name" value="NrfD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="39"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="223"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="262"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="302"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="343"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="369"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="411"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD88067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="576" mass="65330" checksum="D7562E7A5BFE1754" modified="2019-11-13" version="1">MASHYEAPIRRPLVTGEKSYHDVSIDVARPVEGKANKSWWIVFSIALVAFLWGIGCIIYTVSTGIGVWGLNKTVGWAWDITNFVWWVGIGHAGTLISAVLLLFRQKWRMAINRSAEAMTIFSVIQAGLFPIIHMGRPWLAYWVLPIPNQFGSLWVNFNSPLLWDVFAISTYLSVSLVFWWTGLLPDFAMIRDRAVKPFQKKIYSLLSFGWSGRAKDWQRFEEVSLVLAGLATPLVLSVHTIVSFDFATSVIPGWHTTIFPPYFVAGAIFSGFAMVNTLLIIMRKVSSLEDYITVQHIELMNIVIMLTGSIVGVAYITELFIAWYSGVEYEQYAFLNRATGPYWWAYLLMMSCNVLSPQFMWFKKLRTSIMFSFFISIVVNVGMWFERFVIIVTSLHRDYLPSSWTMFSPTFVDIGIFIGTIGFFFVLFLLYARTFPVIAQAEVKTILKSSGERYKRLRENGESLVGTGADSRTSVLRLSDDHHDAVPSQDKKEQLKNLLIGVGVFDAEIQTADDLTVINGIDPKMEETLNSIGIYSYAQVSKMTKREYDLLDEITGAFPGKAERDDWSGQAKKLIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG39</accession>
    <name>A0A5C6ZG39_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminodeoxychorismate/anthranilate synthase component II</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_16380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071704">
        <property type="term" value="P:organic substance metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd01743">
        <property type="entry name" value="GATase1_Anthranilate_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006221">
        <property type="entry name" value="TrpG/PapA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00566">
        <property type="entry name" value="trpG_papA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GATase" evidence="1">
        <location>
            <begin position="5"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="196" mass="21793" checksum="B8F98D6485D43C92" modified="2019-11-13" version="1">MNNILVIDNYDSFTFNLVHYLEDLDCKVTVKRNDKLNLEEVEAFDKIVLSPGPGVPDEAGLLKAIIATYAPTKSILGVCLGQQAIGEVFGGKIINLEEVFHGVATTLTVTVDDESLFDDMEKSFDVGRYHSWVVDTKLPDVLEATSFDENGQIMSLRHKFYDVKGVQFHPESVLTPNGKQLLANWVRIPAKLPSHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGA1</accession>
    <name>A0A5C6ZGA1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_16095</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000021">
        <property type="protein sequence ID" value="TXD87672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022926587" evidence="1">
        <location>
            <begin position="19"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="COesterase" evidence="2">
        <location>
            <begin position="29"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="298" mass="33269" checksum="CAA6D92F923BD8E8" modified="2019-11-13" version="1">MKQLILIVLLMFAFQSFSQDLETYTYAIKGKDTLKMDVYSPKRIKKKDSLPVVLWMHGGGFSGGSRANPDEVRLMEYLTENGFIGISISYRLLRKGKPTGFGCECTKEEKRFIFANAAIDYLDAANYVFNNAKQLKIDTSKIIAGGSSAGAEGMLSAVFMKDYFMADAARYQHLKFAGVWSLAGALMDVNYITKTNAIPTVMFHGTADNLVPFGIAPHHFCKMQQPGYMILYGSKPITEKLDELGTSYYLHKVIGGGHELSSIPFDQLDTLLEFINKTMLNSEVIQTEKIITKSILQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGC6</accession>
    <name>A0A5C6ZGC6_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CYTOSOL_AP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_10245</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011356">
        <property type="entry name" value="Leucine_aapep/pepB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000819">
        <property type="entry name" value="Peptidase_M17_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11963">
        <property type="entry name" value="PTHR11963"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00883">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CYTOSOL_AP" evidence="6">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD89138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="84" mass="9301" checksum="4071DB0B9D09F765" modified="2019-11-13" version="1">MPLYEDFESDLHSDIADIRNLSGKPIAGAINAAKFLEFFTESHENWMHLDIAGVSFGDSPYAKMKSASGYGIQLMVEFVKAKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGI0</accession>
    <name>A0A5C6ZGI0_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Phosphoenolpyruvate carboxykinase (ATP)</fullName>
            <shortName evidence="8">PCK</shortName>
            <shortName evidence="8">PEP carboxykinase</shortName>
            <shortName evidence="8">PEPCK</shortName>
            <ecNumber evidence="4 8">4.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 9" type="primary">pckA</name>
        <name evidence="9" type="ORF">ESY86_13520</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + oxaloacetate = ADP + CO2 + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:18617"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.1.1.49"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="8">Binds 1 Mn(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.49" evidence="4 8"/>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004612">
        <property type="term" value="F:phosphoenolpyruvate carboxykinase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.449.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00453">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001272">
        <property type="entry name" value="PEP_carboxykinase_ATP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013035">
        <property type="entry name" value="PEP_carboxykinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008210">
        <property type="entry name" value="PEP_carboxykinase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30031">
        <property type="entry name" value="PTHR30031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01293">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006294">
        <property type="entry name" value="PEP_crbxkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68923">
        <property type="entry name" value="SSF68923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00224">
        <property type="entry name" value="pckA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="8" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="7 8 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="8">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="202"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="222"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="238"/>
            <end position="246"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="288"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="325"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="444"/>
            <end position="445"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="450"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD88317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="544" mass="60825" checksum="6740EDB9443BD515" modified="2019-11-13" version="1">MKIVSKKPKNSDLKKYGLENVTAHWNLDGETLQKITVEKGQGTETDNGTLCVNTGKFTGRSPKDRFLVKDDYTKDKVWWGRINKPLEPANFERLYNEVTSYLSGKEIYVRDAYVCADPKYRMNVRTITEYPWSNYFVKNMFISLKADEIENFDEEWLVLCAPGYEAKDPESFGLRAGNFSILDFTRKVALVAGSAYTGEMKKGIFSALNLILPTEKNVLPMHCSANVGEEGDTAIFFGLSGTGKTTLSADPERKLIGDDEHGWADDNTIFNFEGGCYAKVIDLTEENEPDIFRAIKPGALLENIVFKEGTKEVDYSDSSITQNTRVSYPIDHIDTIVEPSFAKNPKNIFFLTCDAFGVLPPVSKLTPGQAAYHFISGYTAKVAGTEAGINEPVPSFSACFGEPFMPLHPTAYAEMLSKKMTDAGVNVWLINTGWSGGPYGVGSRIKLKYTRAMISSILEGELEKVDYEQHPIFGLYMPKYCKDVPTEMLDPMNTWLQKGAYISKAIQLAHSFHLNFDKFVNQASQDIMNGGPLIDAHQVMDHHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGK2</accession>
    <name>A0A5C6ZGK2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PASTA domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_09365</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005543">
        <property type="entry name" value="PASTA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005311">
        <property type="entry name" value="PBP_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036138">
        <property type="entry name" value="PBP_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03793">
        <property type="entry name" value="PASTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03717">
        <property type="entry name" value="PBP_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56519">
        <property type="entry name" value="SSF56519"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51178">
        <property type="entry name" value="PASTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="PASTA" evidence="3">
        <location>
            <begin position="610"/>
            <end position="667"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="667" mass="74864" checksum="0DB62780C388A8B1" modified="2019-11-13" version="1">MAITEKNILNRLYFVAGILFVFALAVVFKLCTIQFVHGDKYRELAEGRIVKNIEIPANRGNVYSADGSLLATSIPKYDIRLDAIQPSQKTFNALIKPLGDSLAKYTGRSSSYHQNSIKKARNNKNRYFLLARNISYSNYIRLRNFPMLELGAIKGGLIVEQTTRREHPMGGVAERTIGYERTDEDGNVTRPGIDGAFGVKYLSGVNGKRLSQKIGNGQWKPIVDYDQVEPKDGYDVYTTIDVNIQDIAHHSLLGQLEYYEAEHGCAIVMDVKTGEIKAISNLGRNENGNYYERLNYAVGESHEPGSTFKVMALMAALEDKVIDSSTIVDTKNGVKRFYKRNIYDSHHGGYGKISAARALEVSSNIGLATIIDDNYSKDPNKLIDRFKEWHLDKKLGVAIIGEGKPVIPEPGDKLWSKNALPSMAYGYNLRMTPLQVLAFYNAIANDGELVKPRFIKSVKEFDKYIKVFEKEVINPKICSDNTLNVIREILKNTVERGTGSKLYSENFSMAGKTGTAQTEYWMKDWKDNKRYVSSFAGYFPAENPKYSCIVVIHRPSIKKGFYGADVSGPVFKRIAQKIFTDTPLIYDLETLEIANSDVEKEFQSYYTTAQTYKTIMPNVVGLPTMDALALLENMGLKVKMQGVGKVKSQSINKGVKVERNQIIILNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH14</accession>
    <name>A0A5C6ZH14_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphorylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11725</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="SSF53167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNP_UDP_1" evidence="1">
        <location>
            <begin position="30"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="292" mass="32420" checksum="38D7A7BBC59735BB" modified="2019-11-13" version="1">MPIKDSELILNPDGSVYHLNIKPENLANTIITVGDPDRVDSITKHFDTVDFKTRKREFHTQTGTYKGKRLSVISTGIGTDNIDIVLNELDALVNIDLKTREIKTKLTTLNIIRVGTSGSIKADIPVDSILISAYAVGFDSLLHFYDSEHVQDFEISEALKSQTNWFEKKSDPYVVSCDSSLLDHFKSDQTAVGFTATNVGFYGPQGRVLRLGIQDKDLNAKLARFDYEGKTISNLEMETAGIYGLSKLLGHKALSMNAIIANRATGRFSADPTKIVTELIDYTLKKIKNLDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH36</accession>
    <name>A0A5C6ZH36_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ATP-binding cassette domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_10885</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="191"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="223"/>
            <end position="230"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD88988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="416" mass="46600" checksum="A93B237327489F0B" modified="2019-11-13" version="1">MKQPRHWFIYTNNQSNKKRFLDQLYTGAYLEEYGQCSQDKTRLFSDSEIDRLISEEERHDFKTVTTPNDQPLNAMSSGEQKKALFSELVKHPPELLILDNPFTHLDMASQSELKQLLSEIATQSSIIQLSSRVADKLPFIKRCSVLQADHQITAISEADLKTHSFPKHIVLNSKNIPPPLKPMEMEGKEVIVFDAVNVSFAERPILQNINWTVNKGEFWQLSGKNGSGKTTLLSMITGENTKGYGQNLVLFGKLKGSGESLWEIKKQIGYVTPAMTRLFNGYHSVVNMVVSGLFDSVGLYQKPSDLQLNLAAQWLEVLNLKPLKPTNFKDLSLGQQRLVMIARAMIKHPPLLILDEPTADLDDDSAALFVALVNKIAQESDTAIIYVSHSLEPSLQPSHHYLLEANALGSTGKVVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH54</accession>
    <name>A0A5C6ZH54_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Translocation/assembly module TamB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_10500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD89008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007452">
        <property type="entry name" value="TamB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04357">
        <property type="entry name" value="TamB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD89008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1456" mass="164825" checksum="1D45C02DFFA1573F" modified="2019-11-13" version="1">MLFFSIPAVQTYLGKRATKRLNDAYGTNINIGKVGLQFNGDVELKNVFIEDYKQDTLINIDELNTSIISFKNLYYGKLVFGDIDIINLTFNVRTYLNEEDTNLDVFVQKFQSDNPDQNKSEFLLSSSDVSILNGKFNFINDNKANPKLFEFYDLNINATNFVISGSDVNARINTLAFKDSRGAYVKNLITNFEYSLNHMSFGDLSIRTEKSILKGNLRFDYDREDFANFADKVIVTANFKDSELFLNDLNAFYNEFGKNQTAYMDVDFSGTLNDLYAKNLKLRTSSRTQLYGDLNFKNLFNTEEGNFSLDGRYDNLSTNYYDLKALLPNILGEAIPSVFSKFGNFTIRGQSYITTSTIDADLNISTDLGRIISNMRMKQVNDIDNAYYVGDIVFEDFNLGKLLNNPKIGNTSFDLDVDGRGFTLDNLSSQIKGRVYQLEYNDYNYRRIDVSGKLGNRIFNGFVESFDENFKFKFDGLADLSEDINTLNFTANVDYANLRALNFISKDSISVFRGMVTSSIKGSNIDDAFGTLNFQNTTYINEHDEYYFKDFEIESQFSGSKRTITIDSPDIIEGSLSGDFKFKDIGKLVENSVGSIYTNYVPNIIETDQYLEFDFRIYNKIIEVFYSELELGANTRLKGRMETDEKQFNLSFNSPQIKLFDYFADDISILIDNSNPLFNTYIEMDSLSTKYYDVSKFSLINVTQRDTLFIRSEFSGGKQNADRFDLSLYYTIDESNKSVVGFRKSNVTFKENTWTINEDRNKFNKVAFDRDFKNFDISQLVMSHMGEQIELSGVLRDSTYKDLNLDFTDVDLAKITPRLDSLSLGGVVNGKLDLLQEDGVYLPKSNVIISDFRANDYELGTLRAMIIGNQSLTNYTVDVTLKNDNLKSLDAKGTLDFDNKDIDIDIDFDEFLLDPLDPFGQGVITNIRGLVTGNAKVSGKLDNPNYSGELLLDNAGLSIPYLNIDYSFDFDSKVILESQRFVFDEVEITDSEFFSRATLNGYISHNNFSDWRLGLEIDTKRLLVLNTDYDEEQLYYGTAFVNGSATIKGPTNQLVIAVDGSTAQGTVFKIPLNDLETYGDNTYIHFLSPEEKEARLRGEVIRNTEVKGLELQFDLIVNPYADIEIVIDRNSGSTIRGTGNGNLLFNINTNGKFQMFGDFQIVQGTYNFAYAGLVQKKLTVEPGGSIRWEGDPLKAQIGLKAIYKTQANPSVLLDNPINRSIDIEVEVNLVGQLEQPEPDFTFNFPNVSSTIKSELDYRLETKESRTNQALFLLSTGSFASEISLGQQAYGTISDRVNSFFNSFLTNEDGKLQVGVNYELGEQTTDYETDDRLGLTLTTKISDRVMINGKVGVPIGGVNQTVIAGDVQIDVLLNDDGTLTAKFFNRENSIQNFGERIGYTQGAGIAYNVEFDTFKELIQIILYGNRKDEIVSEAKKKAQDETEFTPDFINMKSEKDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH58</accession>
    <name>A0A5C6ZH58_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dipeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08830</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="1">
        <location>
            <begin position="199"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="462" mass="51161" checksum="82DE9FE0A4927129" modified="2019-11-13" version="1">MKSAKPYIEENKQRFIDELIDLLKIPSISADSAYNEDVKNAAQVVKEQLEKAGCDSVEICETPGHPIVYGEKMIDPKLPTILVYGHYDVQPPDPLDLWNSPPFDPIIKKTELHPEGAIFARGSCDDKGQMYMHVKAMEYMTKTNQLPCNVKFMIEGEEEVGSVNLANFVKNNHAKLKNDVILISDTGMIAKDVPSITTGLRGLSYVEVEVTGPNRDLHSGLYGGAVANPINIISKMIASLHDENNHISIPGFYDKVEVLTEAERAEMAKAPFNLEAYQKSIGINSVSGEKGYTTNERNSIRPTLDVNGIWGGYTGEGAKTVIPSQAFAKISMRLVPHQDWEEITQLFKKHFESIAPAGVTVKVRPHHGGQGYVTPIDGIGYQAASKAYFDSFGKTPIPQRGGGSIPIVSLFEQELQSKTILMGFGFDSDAIHSPNEHFGLWNYFKGIETIPLFYKYFTELSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH87</accession>
    <name>A0A5C6ZH87_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Heme chaperone HemW</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">hemW</name>
        <name evidence="4" type="ORF">ESY86_08700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004109">
        <property type="term" value="F:coproporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006779">
        <property type="term" value="P:porphyrin-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034505">
        <property type="entry name" value="Coproporphyrinogen-III_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010723">
        <property type="entry name" value="HemN_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004559">
        <property type="entry name" value="HemW-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13932">
        <property type="entry name" value="PTHR13932"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06969">
        <property type="entry name" value="HemN_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00562">
        <property type="entry name" value="HemN-like__clustered_with_heat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00539">
        <property type="entry name" value="hemN_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0349">Heme</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="3">
        <location>
            <begin position="1"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU364116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="377" mass="42942" checksum="3A16D16B41AD58CD" modified="2019-11-13" version="1">MSGIYIHIPFCKQACHYCDFHFSTSLKKRDDMIEALAKEITLRRNEFAKQQVETIYFGGGTPSLLTIDELRFLIETVYKYYEVVAHPEITLEANPDDLTTQLLNSFANSPINRLSIGIQSFFEQDLKLMNRAHNAEEAKTCLEEATRLFDNISVDLIYGIPGLSNARWLQNIQTALTFDIPHISSYALTVEPKTALQSFIKKGIIDDVDDDVAQEQFQLLADTLEDKGFIHYELSNFGKAGFFSRNNTAYWQGKAYIGIGPSAHSFNGTQRSWNVRNNSKYIEALALSQLPMETETLTLTDKYNEYIMTGLRTMWGVSLEKVSNDFGALYKTYLLKQSEVFLEQHLLFLDDETLKVTKKGKFLSDGIASDLFMLNLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHA6</accession>
    <name>A0A5C6ZHA6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Insulinase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_10005</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="SSF63411"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022874885" evidence="1">
        <location>
            <begin position="23"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16" evidence="2">
        <location>
            <begin position="42"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_C" evidence="3">
        <location>
            <begin position="189"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="437" mass="49702" checksum="47D6A38C629C3F44" modified="2019-11-13" version="1">MKKLFFLLLLGISQLGNTQMKADDVQTFVLENGMKFLVVEDFSIPNANMYLFYKVGSRNEYQGITGLSHFFEHMMFNGAKKYGPKMFDQTMEFNGGANNAYTTENVTVYTNWFPASAAEVIFDLESDRIASLSIAPSMVESERGVVLSERRTGLENSPWRQLFQSVQATAFQEHPYHWPVIGYEDDMKNWTQGDLERYFKTYYAPNNCVVVVSGALKFEEVKALAQEYLEPIPAQPDPPKVHIVEPPQTGERRITEQKEVATPYLLISYHTPDSKSEDYYALSMLSSILGNGQSSRLYSELVDKKQLATQVFSSFGESFDPSLFSVGAITNKNVDEADLEKAIYAEIDKIKTAGITEKELQKIKNQKLMEFYSQVETINGKSNTLGTYELFFGDYRKMFNAPENYNKVNRKDIQAVAEKYFSKSNRTVGVLKSDVEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHF0</accession>
    <name>A0A5C6ZHF0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_12015</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="345" mass="40287" checksum="0475092D2DDB2CE5" modified="2019-11-13" version="1">MIVTPLDSAILDSKEQYVFYHKMLDFALKELISSVKKHELCTQQELIFFNQYCDLLSYSIEAMRVKYMYDQEDNMKVDLTKSGLPNYLEFRYLFNDLSLKGNYLNKLKDVSELQEEFLTQLLHKKQPIKKDKLFEAASIVYYTSVEQKFIFNRFVQGKIIDAPEGSAASYMTSWSFYDVSNNRPYVCFMYFDYEGKSIESYKQEIYEVLKSTADRDMDLDIMAYGIDRKLPDIQPKHIKRIDLGPFHNVFAKDGDEVTHVILENIANKNIPLESYAVALSIDEVISGSQFTEGGYFSKQTLQKWKTVQHKKYVFAPHRIIQLLYSKTPEIMGTLEKPPFEVSSLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHG0</accession>
    <name>A0A5C6ZHG0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cytochrome c oxidase accessory protein CcoG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ccoG</name>
        <name evidence="6" type="ORF">ESY86_11290</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014116">
        <property type="entry name" value="Cyt_c_oxidase_cbb3_FixG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032879">
        <property type="entry name" value="FixG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13746">
        <property type="entry name" value="Fer4_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12801">
        <property type="entry name" value="Fer4_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11614">
        <property type="entry name" value="FixG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02745">
        <property type="entry name" value="ccoG_rdxA_fixG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="39"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="154"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="196"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="337"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="260"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD88815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="474" mass="54657" checksum="7846D87578867335" modified="2019-11-13" version="1">MSTENESFRDTIGTLTDDGKRAWVYPKKPSGRYYEWRKIVSYGLLAFFLAAPFIKINGNQFLMFNILERRFNIFGFPFWPQDFHLFVISMLIGVVFIALFTVSFGRIFCGWICPQTIFLEMVFRRIEYWIDGDRGKQIRLDKQKWDAEKIRKRLLKWFIFLVISFIIANVFLAYLIGSDKLLGYITDGPFEHLGTLFPLVIFTAVFYFVFAWFREQVCIIACPYGRLQGVLLDNKSIVVAYDHKRGEAENGRKKFRKNEDREALGHGDCIDCFQCVNVCPTGIDIRNGTQLECVNCTACIDECDHIMDSIDLPRGLIRYASEEDIEKKKKFEFTPRLKGYTAVLVILTGFLIGMLMLRNDVEARVLRLPGQLYEHVGETRISNVFTYKLINKTTKSIENVRFELRGFDNGTIKLVSASEVVKVPEQGLAKGTLFIELEQSDLSGDKNELMIDVYSGDELIETTSVNFLGPRSYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHL1</accession>
    <name>A0A5C6ZHL1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Oligosaccharide flippase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_07720</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029303">
        <property type="entry name" value="Polysacc_synt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002797">
        <property type="entry name" value="Polysacc_synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01943">
        <property type="entry name" value="Polysacc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14667">
        <property type="entry name" value="Polysacc_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="116"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="190"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="230"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="267"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="306"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="344"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="376"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="401"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="435"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="458"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="domain" description="Polysacc_synt_C" evidence="7">
        <location>
            <begin position="350"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD89662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="487" mass="55923" checksum="2E65A0035E7938A0" modified="2019-11-13" version="1">MSVLKSLFKQTFFYGLATVLPRMLSFFLVPLYTTKGVLSSVAEYGKVNIIFSYFVMFNVILAYGMETAFFRFFNKEDDEAKVLGTSSISLLVSSFGFFALGLVFQNQIANFISIDAKYINLVIWILLLDALVIIPFAWLRATQKPMRYAVIKIINVCINIGLNLFFLLSLKKIAHQNVVFEAIYKPNFEVSYIFIANLVASAVTLLLLVPFYTKLKFKFDKLLWKKMLRYALPVLVAGVAFSINETFDRILLDYLLPPDVAETQIGMYSACYKLALFMTLFATAYRLGIEPFFFSHSKSENPQKNYALILEFFVAFGSVILLSVVVFADVIKPFIIRSEDYWEAMWIVPIILIANFCLGIYHNLSVWYKITDRTKFGAYISVFGAVVTLAINFMFIKSYGYRASAIATLVAYALMMFLSYYFGRKYYPIPYNLKKIGLYLTLSISLSVISFYYFRTQIFVGITMLIVFLGIVAYNEKQQIQRLLRKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHP0</accession>
    <name>A0A5C6ZHP0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_09475</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022385">
        <property type="entry name" value="Rhs_assc_core"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03696">
        <property type="entry name" value="Rhs_assc_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1459" mass="160786" checksum="CC94483AC8711A57" modified="2019-11-13" version="1">MENMRTIHFRITILLAALLMLPLMASGQEGVPLEGAPLLWGNKNQISNIGFDFSGATISKGRNFFNSLSKPTQSQSWDIMTDKVWASASLYDRHGRPALLTLGAPIGHQFGYSGNFMLNEANNSYTYADFDLSTATIDDPDQVGSNALLRTYYSINNSDSPYQDITDYPFSRKVFSKLNPGNVLRVIGGNKIGGEWKQGYSFTMPAGTELSASVAFGSGYDSHGNVTKQVVRDVNGVDTVVFSDTDGNTIAAARSGNEQGTPQTYATTLEIGELGYIDIHLPKGAGVFSVLNPSATASGPLKIYDLITETQLSPITTASASRSVPSGFYRIAVSDTYGYGSSDSGPITVTHQVNYYDYSLNYFDRAQRLVSSKQPLNHLESTFSYNSLGQLLETTSPDEGTAMFLYRSDGQIRFSQNSEQALISEVSYTNYDNLGRPVESGAFRYGNAFGTLSAYVDVAVLGSWAGNFSDNHYTVYDMPGSGLEEKLKNCGLPARDYAQTFVAGNVSKTSTGNPWTTTTWYSYDVFGRVRWIVQDIPGLSCLKTIDYVYDPVNGQVLEVDYQRHSRSERFVHHYRYDDAGRLGQVRTSTDGAAQELQATYRYNESGSLRRTELAGNLQGIDYVYNLNGQLKAINHPSLSVGNDPGGDGGGNGFLTDVFGLAIDYHNGDYQRPGTLTPIARQTNTGNEQYNGNIKALHSSTQGFSSRDEFNTYMYGYDKNNWLSTANFGASDQVSIGGGQYQNNFTADSNQDYSVSNLSYDANGNIQGLKRNGVTNGSGTNDMDDFTYHYDGSNKLQHVGDTGDNIDPDRYDDLRDQTNNGLPNYTYNDIGQLTVDVEGRMLYEYNSSGLVKRIHTFSNTVGAGNGQFTLYEQDYGNVTDTELLYWSEDSGTASINYSGVYDIKKLDCPSLSVQYGRSLHLRLNGNRRARRDFNVIPGVGHELDLDVIAFENDATGFKITIYDKGGTLPIATSSYNTALAPINDPDHTGSRCSLYYDRDVTLGFTPLTSMVRFEIELYTNAPSRDTHVFLDNIQIALGVEPKLALYYNDRGQRVRKEAYVNGSPKTNTYYVRDVGGSTVAIYSRVVESAQRGEVPEEHPVYGSSRIGVFYRDQRDTDKGTYAYQITDHLGNVRAVLVKDGQNALSLTNQTDYYPGGMAMPNRNIVGDYRYDYQGQELDQETGKVAFELRLYDPRINRWLTTDPYGQYHSPYVGMGNDWINGIDPDGGWKTKWGRFWGWVGNGFKGEFYNSDVATGQGKYGLAFDYGGGSGEGELTGSFMAVSGADLDSWNGNQALNNWRFTEDGSGYDIAVIVQKQHNFFGSIENSLNNSDSALSSVGSMGYNMVDDVYSFGTHFSLLSPNGPRHLNGNGIVRGSSEGIDTGINGMLTIATFGRLKKPTMNMGQFNAEYKGVLTRTIKSSKIKGIILKNMNRLNKYWGRQVIAPNLKTVKGVSESIFGAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHQ8</accession>
    <name>A0A5C6ZHQ8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Type II secretion system F family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_09580</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GSP F family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.81.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003004">
        <property type="entry name" value="GspF/PilC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018076">
        <property type="entry name" value="T2SS_GspF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042094">
        <property type="entry name" value="T2SS_GspF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30012">
        <property type="entry name" value="PTHR30012"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00482">
        <property type="entry name" value="T2SSF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00812">
        <property type="entry name" value="BCTERIALGSPF"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="139"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="348"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="8">
        <location>
            <begin position="44"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="8">
        <location>
            <begin position="246"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD89281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="377" mass="42602" checksum="F57A3DAB84AE924D" modified="2019-11-13" version="1">MGFQLDNIATTKTTKEKRPMDTSFLQKEITLFGSSFSNKIKEDFYTELGVLLKAGITLKDALELIQNSTKKKLHKTKLGTISETIVSGLSLSEALKNQKEFTDYEYFSIKIGEETGSLTEVCMQLGSFFARKNEQRRNLISALTYPIIILSTAVLVVIFMLQFVVPMFQDIFEQQKVELPAITKLIIAASQFLKAYGWVLLLLFIGLVASRAFLNKKPWFKKAKDQLILELPLIGDFVRTVYLSQFTQAVALLTASKVPVVNSIQLVKQMIDFYPLQKALAQVEKDILQGSSLSESLKAHKLFDDKMVAMVKVAEETNQNEFIFERLNMQYNTQVQQRSKLLSTVMEPFIIMIVGVLVGVILIAMYLPMFKLSSVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHT5</accession>
    <name>A0A5C6ZHT5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Acyl-CoA dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_12155</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045008">
        <property type="entry name" value="ACX4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43188">
        <property type="entry name" value="PTHR43188"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="8">
        <location>
            <begin position="79"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="194"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="304"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD88492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="453" mass="51106" checksum="34F2CD81A2328A92" modified="2019-11-13" version="1">MQLFSKIKNVIHLMKEVDFNQLSEISKKIDISKIMKTVGELDEKQLDGMMKMLTERGKKGQHQLPPIDGDFYDMDLKLTQEQRDIQMRVRNFMENEIQPIANDYWKKAEFPHEIIPKMAELNICGVAYEGYGCPNLPFVMEGIIAEELARVDVSISTFFGVHSGLAMGSIYLCGSEEQKQEWLPKMQKMELIGAFGLTEPNVGSAVSGGMETTCRIENDEWVLNGQKKWIGNAAFADVTIIWARDETSDKVKGFLLRKGTPGFTTEKIEDKMALRTVQNAIITLKECRIKETDRLQNANSFRDTAKVLRMTRAGVAWQAVGCARGAYENALKYTKKREQFGKPIASFQLVQNHLVEMLSNLVAMKTMVYRLSELQDQGLLTDEHASLAKVFCSMRTRDVVSHAREVMGGNGILLEYNVARFVADAEAIYSYEGTKEINTLIVGRAITGYSAFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHU5</accession>
    <name>A0A5C6ZHU5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UDP-2,4-diacetamido-2,4, 6-trideoxy-beta-L-altropyranose hydrolase</fullName>
            <ecNumber evidence="3">3.6.1.57</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pseG</name>
        <name evidence="3" type="ORF">ESY86_07920</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.57" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020023">
        <property type="entry name" value="PseG"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03590">
        <property type="entry name" value="PseG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="19"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="253"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR620023-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR620023-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="339" mass="38098" checksum="8EF5C4D34B84167B" modified="2019-11-13" version="1">MTKKIIFRADGNGETGLGHLYRLFSLVETVRDHYEFVFLTKASSTHSVIPESYNLGVIPENSSLSEEANWLSENFSAENHIIIADGYQFNAAYQKAIKSKGYKLVYIDDLASEHMYADVVVNHSPNIAQSNYKCETYTNFALGTKYALLRPIFLKLAKQSRSIEKIDTAFVCFGGADLFDLTGKATKALLGMSLFTIVHVVLGAAYQHENILMLKESHPDRLKIHKNLSAEALAKVMQSCNFAIAPSSTILYELSCIKMLILSGYYVDNQELIYKGFLCKKAIFKGGNMTNYQESDFSELMHSILNSGQFEEQIRAQQNMFDDQIASRHLKLIGPLCCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHW9</accession>
    <name>A0A5C6ZHW9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA pseudouridine synthase A</fullName>
            <ecNumber evidence="4">5.4.99.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridine(38-40) synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridylate synthase I</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA-uridine isomerase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">truA</name>
        <name evidence="9" type="ORF">ESY86_10485</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 7">
            <text>uridine(38/39/40) in tRNA = pseudouridine(38/39/40) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:22376"/>
            <dbReference type="Rhea" id="RHEA-COMP:10085"/>
            <dbReference type="Rhea" id="RHEA-COMP:10087"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="EC" id="5.4.99.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 7">Belongs to the tRNA pseudouridine synthase TruA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.12" evidence="4"/>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106029">
        <property type="term" value="F:tRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.660">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00171">
        <property type="entry name" value="TruA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001406">
        <property type="entry name" value="PsdUridine_synth_TruA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020097">
        <property type="entry name" value="PsdUridine_synth_TruA_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020095">
        <property type="entry name" value="PsdUridine_synth_TruA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11142">
        <property type="entry name" value="PTHR11142"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01416">
        <property type="entry name" value="PseudoU_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001430">
        <property type="entry name" value="tRNA_psdUrid_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="PseudoU_synth_1" evidence="8">
        <location>
            <begin position="150"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4 5">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 6">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001430-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001430-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD88916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="260" mass="30259" checksum="4C65FF266858015A" modified="2019-11-13" version="1">MFKKRFYYLIRIQYLGYRFHGWQKQPKLKTVHFMIDRTLNYILEGKEFKSLGSGRTDAMVSANESAFELFVYEEIEDESVFLELFNKNLPQDIRALAIEEVDANFNIIQDSKIKEYVYLFTYAEKCHPFCASLMTTFLDDLDIELMKTGAKLFEGTHNFKPYCFRATDEGLYEREVLHCELSENSLFTANFFPKKSYTLIVRGKGFGRNQIRLMMGTLVNLGRGDVTLEYIENSLKTDSTLKMEFIAPASGLILNKVAFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHY2</accession>
    <name>A0A5C6ZHY2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SDR family oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12440</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="240" mass="25625" checksum="1964226EAF5B7B4E" modified="2019-11-13" version="1">MESLKNKVALITGGTKGIGYGVAEALLNQGLKVVITSRDEDSAKKAAKELGAKTNAAAHILGVKADVRKLESQQEAVKQTIDKFGKLDIVIANAGVGKFASIEDMTSQEWNDVIDTNLTGVFNSIKASVDELKKNKGYYITISSLAGANFFAGGAAYNASKFGVTGFTQAVMLDLRQHGVKVSTIMPGSVSTHFNGNEPSEKGDWKIQIEDLGELVVDLLKMNPRTLPSKIEVRPSMPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI74</accession>
    <name>A0A5C6ZI74_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_11835</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="84" mass="9467" checksum="9E29D43E34BFA4AB" modified="2019-11-13" version="1">MLVKNLEHLKELANNEKGDLEDFYVSLAGGIVKSGKRIFYDKEFDSFSLVNEVDDSFQSFDSSEIGEVTNLLEAISKNALFKDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI98</accession>
    <name>A0A5C6ZI98_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF547 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_09095</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006869">
        <property type="entry name" value="DUF547"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04784">
        <property type="entry name" value="DUF547"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5035250346" evidence="1">
        <location>
            <begin position="25"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="DUF547" evidence="2">
        <location>
            <begin position="99"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="268" mass="30049" checksum="7A17291A470D149B" modified="2019-11-13" version="1">MKTLITYVAIFSMAICTTSCNLLTAAGMSSQGQPTKKVQGDLSSSTLNSAVNVDHSAFDKLLKKHVNNKGFVDYKGFSNDQAQLEAYLKMLSELDPSDAWSVQELLAYYINLYNAATVQLILENYPTKSIQDIDKAFIKAFVKIGDSELSLGGIENGVLRKMNEPRIHFAINCAAYSCPKLMNEAYTSAKINEQLEAATVEFINSDKNDITKTNPKLSKIFDFYTSDFKVDGKKDLIGFVNQYSKTKIDTSTEYTFKDYDWSLNEQRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIA4</accession>
    <name>A0A5C6ZIA4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter permease subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_09150</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="5"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="55"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="92"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="123"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="181"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="224"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="59"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD89214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="259" mass="29731" checksum="C31DE5D7202DB445" modified="2019-11-13" version="1">MIKKLLQYGFIVSIGFPVAFLLMLSLGRRWAYPNVLPEQMNFANWEFLQRSDSKLFQAFFVSLGISLCVAIFTTSIGFLISKLIAYSKNRNFYLVLAYIPYLLSPVIMAVIFQYYFIITGLTGTFLGVIIAQFLVAFPFGIIIYINFWNPQLKSIEELSYTLGGSRWQTFKKVLLPLSKNAIMLCFFQVFLISWFEYGLTNLIGSGKVRTLTVSVFNFVTEANIFYAALSCCLLILPPMLLLYINKRLIFFVEKTKIEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIB0</accession>
    <name>A0A5C6ZIB0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">T9SS type A sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_09705</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012332">
        <property type="entry name" value="Autotransporter_pectin_lyase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013425">
        <property type="entry name" value="Autotrns_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02601">
        <property type="entry name" value="autotrns_rpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Por_Secre_tail" evidence="2">
        <location>
            <begin position="870"/>
            <end position="920"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="922" mass="97115" checksum="FAB6CDEE57849D22" modified="2019-11-13" version="1">MIQKYMFLKKQIFSIFGLLIILLFSATLHSQQQVFSRSNVSTGNWGDAQLPWFYQTSHNQGDPDNENSTANLIRIGHNSNLTMTLNGRSYRAKELVFEANANQSRTFNGLALELRHQNGGPSKIQNQSIAAHTFNNTIEIFNGTAEFNPVDGDLIFTSDIYTNNNFIDVFGNNNKTLRLSGNLQGTGGIALKQNSIVEIAGVMTYTGGTAVEAGTFRIMDGGDLSDVTPVTISLGATFDLNNQSITVGSVSETGSSNSGSISLGTGTLTLNGWTGNRFQSNISGSGSLVKNGIGTLSLFGTQDYTGTTSINGGVFSSSVDLASSQIIVNETASFSLTGTEDISVNSLTLNSGGTLTIPTGRILTVNGTLTVDAGATIDTEGSITYGPNGKLAITGTTDIATTDAIFPTINGPQDFEVDHTGTVTLHATRLLAGEILVTNGTLSVTEGVGITAASLNTTTNGTVSLESTSTMYSSLIVNNVSGSGTITYNRFVNSNTNGNDLVSAPVSGQTWGSFLTANGTALLDDGETEPTAYAFAPFDKSTGDFENYTNATTASLESGTGYRAATTDAGTTLAFTGTISTGTETTAIVNSGPFSAPWNLIGNPFPSYLNVRAFLNNSANAALLDVTNVGIYGYDGDASNGWTILNLSNTDDSAVITPGQGFFVAAESDGTIEFTPAMRRIGSSDDFISGRNAELTYLKLQLSTATSNYKTDFYFNTNASLGLDAGYDAGVWGGSAPSFALYSHLVQSNTGVPMALQALSPTSLSDVTVPLGVNANQGEQLTFSISASTLPASVNVYLDDTLANLTTILNNSDYVITPTTALSGTGRFFLRYAENSLSAATNSLNTIALYVAQPTRELVFNGNFVRATIADVYDLQGRLVASQALEQNLAQQRMDVSGLSSGIYIVKLNSKQFSRSEKMILR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIB5</accession>
    <name>A0A5C6ZIB5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DUF1328 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_06800</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009760">
        <property type="entry name" value="DUF1328"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07043">
        <property type="entry name" value="DUF1328"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD89901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="59" mass="6685" checksum="90061AADD9D1E94C" modified="2019-11-13" version="1">MKYNYKLTAFLLSVKFLLPLCFRGISEAAAGIAKIIFVIFIMISIIVFPAFKKIYCSFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIE3</accession>
    <name>A0A5C6ZIE3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Metal-dependent transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_07340</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DtxR/MntR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.60.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007167">
        <property type="entry name" value="Fe-transptr_FeoA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001367">
        <property type="entry name" value="Fe_dep_repressor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036421">
        <property type="entry name" value="Fe_dep_repressor_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038157">
        <property type="entry name" value="FeoA_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022687">
        <property type="entry name" value="HTH_DTXR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022689">
        <property type="entry name" value="Iron_dep_repressor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02742">
        <property type="entry name" value="Fe_dep_repr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01325">
        <property type="entry name" value="Fe_dep_repress"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04023">
        <property type="entry name" value="FeoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00899">
        <property type="entry name" value="FeoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00529">
        <property type="entry name" value="HTH_DTXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47979">
        <property type="entry name" value="SSF47979"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50944">
        <property type="entry name" value="HTH_DTXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH dtxR-type" evidence="5">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD89593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="217" mass="24752" checksum="E30737852B7A380F" modified="2019-11-13" version="1">MTLSEENYLKAIYHLEQLSGSGVSTNALAEEMQTKASSATDMVKKLADKQMLIHVPYQGATLSDAGRSHAVKVIRKHRLWETFLVEKLNFKWDEVHDVAEQLEHIKSEKLIDELDRFLEFPKYDPHGDPIPDKNGKFNTIEKITLTQALENKSYRCIGVKDDSSQFLKYLDSNQIGLGTSFEVVHKEPFDQSVKIKLKDKELVVSQSVAKNLFLETL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZII1</accession>
    <name>A0A5C6ZII1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase family 4 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_10155</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="19"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="187"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="361" mass="41607" checksum="337588A083D9E216" modified="2019-11-13" version="1">MRMSGTKKICIVVTSLAKGGAERSSAMLSKMLSQLGHEMHLVSIVDAIVYEFEGQLLNLGASENPYPNFLSRVNKFLVFKKYLKKHRFDYVIDNRSRPAFIREIIVSRWLYNPKTTIYCVRSFHLETYFINPNFLARWIYKDAFKIVGVAKEIGLEIENTYNLQNVTSIYNPIESLPKPSQENPINGDYILFYGRLDDKVKNISLLLEAYRISQLPKNDIKLMILGDGKDLENIKEKVRQLDFNGMVEFQPFLESPFNYVKHSKFTVLTSRYEGFPRTLIESLALGTPVISVDCQSGPKEIITHEYNGLLVENHNPTALAHAMNRFVNDEHLYQTCKQNAKKSVEAFSMENIAKQWQELLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIR9</accession>
    <name>A0A5C6ZIR9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alpha-1,4-glucan:maltose-1-phosphate maltosyltransferase</fullName>
            <shortName evidence="3">GMPMT</shortName>
            <ecNumber evidence="3">2.4.99.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">(1-&gt;4)-alpha-D-glucan:maltose-1-phosphate alpha-D-maltosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">glgE</name>
        <name evidence="5" type="ORF">ESY86_11445</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1-&gt;4)-glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>[(1-&gt;4)-alpha-D-glucosyl](n) + alpha-maltose 1-phosphate = [(1-&gt;4)-alpha-D-glucosyl](n+2) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:42692"/>
            <dbReference type="Rhea" id="RHEA-COMP:9584"/>
            <dbReference type="Rhea" id="RHEA-COMP:10183"/>
            <dbReference type="ChEBI" id="CHEBI:15444"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:63576"/>
            <dbReference type="EC" id="2.4.99.16"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2 3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyl hydrolase 13 family. GlgE subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.99.16" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030979">
        <property type="term" value="P:alpha-glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02124">
        <property type="entry name" value="GlgE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026585">
        <property type="entry name" value="GlgE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021828">
        <property type="entry name" value="GlgE_dom_N/S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10357:SF203">
        <property type="entry name" value="PTHR10357:SF203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11896">
        <property type="entry name" value="DUF3416"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aamy" evidence="4">
        <location>
            <begin position="194"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Maltose 1-phosphate binding" evidence="3">
        <location>
            <begin position="518"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="377"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="406"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>alpha-maltose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:63576"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="306"/>
        </location>
        <ligand>
            <name>alpha-maltose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:63576"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="341"/>
        </location>
        <ligand>
            <name>alpha-maltose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:63576"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="378"/>
        </location>
        <ligand>
            <name>alpha-maltose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:63576"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="3">
        <location>
            <position position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD88863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="645" mass="74867" checksum="CE0813E1FE5FD2B6" modified="2019-11-13" version="1">MQNQKRVVIEAVKPQINCGEHFIKRVINEIVIVNANVFGDGHDVIAVALLYKHENAKSWSETRMQALGNDEWNASFVVEQQGFYSYKVQAWVDEALNWQHGIIRKIEDGQHVNSELTEGSALLEPISKKATEDEKAFLNACSEAFTDKSQYEKAVDDARSEKLHQLFVQYPEKHHANESKALQVYVDRKKARFSTWYEFFPRSASEEKGAHGTFKDCERLLPRIQNMGFDVLYFPPVHPIGEVNRKGKNNTTAAGDGDVGSAWGIGSKDGGHKALHPQLGAIADFKSLIKKAKAHNIEIAMDYALQAAPDHPWVKSHPDWFKWRPDGTVQYAENPPKKYQDILPIYWESNDYKALWDECLDTMLYWIDCGIEVFRVDNPHTKPYFFWNWLISEVKKKHPNVLFLAEAFTRPKVMQRLAKEGYTQSYTYFTWRNGKKEFEDYLTELTQTDQREYMQPNFWPNTPDINPYHLQGATEAKYIQRYALAATMSSSIGIYGPVFEQMIDQAIPGKEEYYMSEKFQICNYDWSKENKLSLIISRINAIRHENEALQQTNNIKFCDIQNDNLIAFYKWNQEQTNELLIIISLDQYYPQQGHVQLPLQALGLQAGQQVQVTDLITGSSYNWYNEWNYVELHPTLPFHIFKIHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIT1</accession>
    <name>A0A5C6ZIT1_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">dTDP-glucose 4,6-dehydratase</fullName>
            <ecNumber evidence="4 5">4.2.1.46</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rfbB</name>
        <name evidence="7" type="ORF">ESY86_07995</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>dTDP-alpha-D-glucose = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O</text>
            <dbReference type="Rhea" id="RHEA:17221"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57477"/>
            <dbReference type="ChEBI" id="CHEBI:57649"/>
            <dbReference type="EC" id="4.2.1.46"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 5">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.46" evidence="4 5"/>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008460">
        <property type="term" value="F:dTDP-glucose 4,6-dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009225">
        <property type="term" value="P:nucleotide-sugar metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05246">
        <property type="entry name" value="dTDP_GD_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005888">
        <property type="entry name" value="dTDP_Gluc_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01181">
        <property type="entry name" value="dTDP_gluc_dehyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="6">
        <location>
            <begin position="5"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD89713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="348" mass="39989" checksum="5333F2BAF39A3079" modified="2019-11-13" version="1">MKKILITGGAGFIGSHVVKLFVETYPDSHIYNLDALTYAGNLENLSSIEHQPNYTFIKGDINDEAFINELFTKYEFESVIHLAAESHVDRSIIDPLAFVRTNVIGTMNLLNAFKTIWKEDFKNKLFYHISTDEVYGSLGKTGLFKETTSYDPNSPYSASKASSDHFVRAYGETYGMPYVITNCSNNYGPNQFPEKLIPLFINNIINNKPLPVYGDGNYTRDWLFVIDHARAIDLVFREGKNHETYNIGGFNEWKNIDLVKILCEQMDEKLGREKGSSEQLITYVKDRPGHDLRYAIDASKIESELGWRPSVTFEEGLSKTIDWYLSNENWLRNVTSGDYQNYYQKQYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIU2</accession>
    <name>A0A5C6ZIU2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_04980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="167" mass="18682" checksum="DAED6D664E5C1F6A" modified="2019-11-13" version="1">MKHVIITLGLLALVGCKDGKNEETNTKTEAAKPSAEATNEQNNDHSDKVSNVYQNAWTNEIVMNNGNKWQADAPTNEGVQKMQNTMKTQTTSTLDAYHKLAEQLNDDKNNVVKNCTMQGASHDNLHIWLLPLMDKIEALSETKTVEDAAKIKQSIEENINGYNTYFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ07</accession>
    <name>A0A5C6ZJ07_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_05735</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="302" mass="34046" checksum="63E3CB54E4D4CAAA" modified="2019-11-13" version="1">MKKLERVLIVVAVLILTYSCENEPINDPVVNSEQLTFIQEVFTINNQSASTIGFTFDNNQNTKIDYGGSRAEQFFSNGTMNSIQNFDANNVQIGELNFSYNDSKQLTEISISSIENGTTTLQSKLVFEYAANQITSTRTYYTMDGSIDEIDSTNIFTINGANQIIRFDDTGIDAFWEATYADGDLSTILVSGYGNKDGSGNFTHTVNLASDSYQKEKFRFGPEWKNNIMLFNQVGGYSFKQLAELGTHYLSGYTYTSASDSNMQITLSVTYEFDNLNRLTKQTKNKLFFQSAHDHVLTYDYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ76</accession>
    <name>A0A5C6ZJ76_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10015</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="L30e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="SSF55315"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SpoU_methylase" evidence="1">
        <location>
            <begin position="94"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="238" mass="26267" checksum="0D5F3EA33C5DDC12" modified="2019-11-13" version="1">MLSKNTIKLIASLSQKKFRTQHQLFIVEGVKGIQEFLDSSFELYQLFATEANFSAETILISEKELQKISNLKSPNTALAIFKIPKQKTAEANGLILVLDEIRDPGNLGTIIRLCDWFGVKTLVCSEGTVDCYNPKVVQATMGSLARVHISYTNLSNYLKTANSAVFGTFMEGNNIYTEELPKEGIIVMGNEANGISLEVEQLIHKKLSIPRFGNLQTTESLNVATAAAVVLSAFRRGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJC6</accession>
    <name>A0A5C6ZJC6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Gliding motility-associated C-terminal domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03305</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001434">
        <property type="entry name" value="DUF11"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01451">
        <property type="entry name" value="B_ant_repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022923610" evidence="1">
        <location>
            <begin position="28"/>
            <end position="1943"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1943" mass="207099" checksum="012EE9F2A522C77D" modified="2019-11-13" version="1">MLNITYLKKLYRSFWLLLLLMSFKTFAQAPTSFPCDGTLFYQTIQLDSSIAGVGSAGDFVLYTVNPDNGAFTFFSNLSVDDDGAGTGDVALIGTINGLGFNTIDGLLYGIDSTLDYLYRITPNGFVENLGIISGPISASNNYSGTFDNNGIYYVLGNNQKLVSIDLSSEVNAGDPLVSTLVYDVGKRSPDIAINPTNFKMYGWDGARRQLFSVDLNNGDVNVIGPAANTSNYDTFGALYFTAGGQLFGYGNDVTVGGSGNTQESVVQFNLSTGIPTTIGLGISVTANDGASCPFGFELFKDAPAAVDLGQVFTYTFTISNATSDLLQNLEFVDNLMSGIVFASDPYNQTNGLSTVGSTNGQTSANLIINNIPVGSSTFQIDVITDCSVQNMVISNQATLASEFLTVVSDDPQTSGITNTTITNIEDPTINVPDPLQIEGCDISVLNAASAVFPLNTTSASSDIKDIFNTVADYTTTASQNITSITYIDTIVDEEACPIVVNRAFSLTSTCGTVSIITQVINVIDTVDPIFQESLPADLTFECSDEIPVAETLTATDNCSQATVAYSETIIQGDCPSQQTIERTWTATDECANTLVHTQTISIDDTTAPVAPEAPADITIEESDPNNVPAVTLTAVDNCSGEIDATSVDTVDDSDPNNIFIVRTWTFVDDCDNNSSISQTITLFNNPSFTCDGTVFYQTIKINQDIENVGSAGDFILYLVNPSGDFSFFANLSVDDDGAGTADEALVGSINAIGFNTLDGLIYGVDSTNDYLYRILPNGFVQNLGIVSGPISNTSNYAGTFDNNGTYYILGNNGHIVSIEGTEDIHPGDPIVSTFLYDLNLNSADVAISPSDLKMYGWKSSTRQLFRVDLSTGNIEIIGPDANTSNYFSFGGLYFTASGQLFGYGNDTNVGSPGNSQESVVQFNLSTGEPTTIGIGVEVTENDGASCAFGFELLKEAPDTVDLGQTFTYTFTIANATNDILNDLEFIDNLVPGLVFTSDPYNITNGMTITGSTNGLTSANLDISAIPTGSSTFQIDVITDCSITDMVISNQATLSSEFLTVTSDDPDTAGVTNTTLTQIIDPTISVPNPLTIEGCDISVVNVETAVFPLSTTMSDDIKDVFNTLEDYTTTAPQNITSITYIDTVVDEDSCPIIINRVFTLTNTCDVSTTYTQVINVQDSTAPVTPEAPEDLVFECNDDLPMSMDLTAVDNCSGEITVSPVMTTDDTNPCNVIMTFTWNFTDECGNTSSISQIVRVTDETAPVAPEVPADMTYECIDDIPEGVELSTLDYCAGELTTLPVDTIDDSDACNVVVTRTWTFTDACENTTAVSQTITVIDTTGPTFTVPNDIAIDCDQDPTDITLTGGVADAVDNCAANALETSYSDSITDGTCENSSIVSRSWTVTDPCGNATILVQTITVQDATAPSFTVPADITFECDTDVTDLSITGDVTDEADNCATGLDATYTDETSNNDSCTSTIIRTWTLTDACENTTTQVQTITLQDDTAPSFTVPADITFECDADVTDLSVTGDVTDEADNCATGLDATYTDETSNNGSCASTIIRTWTLTDDCENTTTQVQTITLQDDTAPSFTVPADITIECDEDATDVSITGNVTDATDNCDTELEATFTDDVVAGECDNSSVITRTWTVADACDNSTTLVQTITVQDSTAPTLVGDYEANVVLACGEDTPEIPELEFVDACSETVNVDFTENTEDEAAIVRQWIVSDACGNEAIFIQTISINEQGEITVDNSTDLCIEDDFDTDLFDLLSGDFDTNGTWTEASGNAVIDGSFFNPTSLLDASGDYPDSAIRDYVFTYTTTGNCALTVDVTVAINDECVVAPALPCDRDNVVISKAVTANGDNINDEFSITGVETCGFTYELQIFNRWGAKIYENFNYQNDWNGTASSKSIGSSGFVPTGTYYYILNIKNSGFEPIAGPIYVSTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJD3</accession>
    <name>A0A5C6ZJD3_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 7">Transcriptional regulator MraZ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">mraZ</name>
        <name evidence="10" type="ORF">ESY86_09350</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="7">Forms oligomers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
            <location evidence="7">Nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the MraZ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009295">
        <property type="term" value="C:nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16321">
        <property type="entry name" value="MraZ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16320">
        <property type="entry name" value="MraZ_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1550.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01008">
        <property type="entry name" value="MraZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003444">
        <property type="entry name" value="MraZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035644">
        <property type="entry name" value="MraZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020603">
        <property type="entry name" value="MraZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035642">
        <property type="entry name" value="MraZ_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038619">
        <property type="entry name" value="MraZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007159">
        <property type="entry name" value="SpoVT-AbrB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037914">
        <property type="entry name" value="SpoVT-AbrB_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34701">
        <property type="entry name" value="PTHR34701"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02381">
        <property type="entry name" value="MraZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89447">
        <property type="entry name" value="SSF89447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00242">
        <property type="entry name" value="TIGR00242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51740">
        <property type="entry name" value="SPOVT_ABRB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 7" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="SpoVT-AbrB" evidence="9">
        <location>
            <begin position="7"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="SpoVT-AbrB" evidence="9">
        <location>
            <begin position="83"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD89240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="155" mass="17517" checksum="491F557D6FA1A638" modified="2019-11-13" version="1">MNPLIGTYECKVDAKGRLMLPAAIKKQLLPALQNGFVLKRAVFQSCLELYPMSEWDVLMQKMNKLNRFKKKNNDFIRRFTAGLKMVEIDAAGRLLIPKDLVAFSGISKEIVISSAINIIEIWDKDKYEQAIDDATGDFADLAEEVMGQDDDDELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJL3</accession>
    <name>A0A5C6ZJL3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_11370</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="189" mass="22208" checksum="EBF411FF72968DEF" modified="2019-11-13" version="1">MNIKKKFTILTCFLALTSQGQIDTRFSDKSSYFEYIDRKYAIDSTKIYYTLDATKKTIFYFPAFTYFIRKDKIITIDEVANELESYCPPKKLFGQLSYELVSNLLEQQNYEVDLILKNLHSNDILDQNDEIVAVFLFSVDYKKLGVRYIKHKKKLENLGFKTIILSMDMPSIHGVTDYSKINQLRVKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJM4</accession>
    <name>A0A5C6ZJM4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">EthD family reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009799">
        <property type="entry name" value="EthD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07110">
        <property type="entry name" value="EthD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02118">
        <property type="entry name" value="TIGR02118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EthD" evidence="1">
        <location>
            <begin position="16"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="104" mass="11289" checksum="2B67F81A91529E38" modified="2019-11-13" version="1">MIKVSIMYPNGKDVEFDAAYYKNNHLPMVSKAVGNALKGLELDLGIGSRVPGEPAPYIAIAHLNFEDVASFQAAFGPHAETFAADVKNFTNVQGQMQISEVITF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJX0</accession>
    <name>A0A5C6ZJX0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_03825</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="349" mass="38011" checksum="FF8D7AC45893F5BF" modified="2019-11-13" version="1">MKRILFILMSGSLLFSCGNEPKSKVTKTVSEVTIETILSDSLLSFRAIEILDDGNLAFAGSQNSYGLYNTKDKSLSVTKQKMDSLEMEFRAVAHTSADFFMLSVGSPAFLFKTGDAAKMELVYTEAHENTFYDAMKFWNNKEGIAMGDPTNGCISIIITRDGGTTWKKVACDDLPKAKAGEAAFAASNTNIAIVDNHTWIATGGTASRILYSADKGATWEIFETPIIQGAATTGIYSLDFYDTKNGFAIGGDYTKADANSANKIRTKDGGKTWELVAKDESPGYRSCVQYVPNSDAKELVTVGFKGIDYSKDSGNTWTHLSDEGFYTIRFLNDSTAFAAGKGRIAKLKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJY2</accession>
    <name>A0A5C6ZJY2_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phage_int_SAM_5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_04365</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025269">
        <property type="entry name" value="SAM-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13102">
        <property type="entry name" value="Phage_int_SAM_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phage_int_SAM_5" evidence="2">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="145" mass="16745" checksum="5E51A6E8E0DEB016" modified="2019-11-13" version="1">MKDYELFMVGKGKSYTTIGIYTRTLRAVFNNAIQENDIGNDIYPFGKNQYKIPRIKKVKKALDSVQLKTLFNAKVANENEGKVKDFWFFSYACNGVNLKDIALLKYSDIADNKFTYNRAKTFDKSSEKTELTIYLTEFTKSVIKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK06</accession>
    <name>A0A5C6ZK06_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Efflux RND transporter periplasmic adaptor subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_05075</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HlyD_D23" evidence="2">
        <location>
            <begin position="59"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="374" mass="41851" checksum="242035769FEFC182" modified="2019-11-13" version="1">MKPIYTILFSLILVACENSEKKSDTPEAVELDSNEIAVSTSQFEGEQMQLGKLTPHAFNQLVRANGMIDVPPQNKAIISTFMGGYITKTPLLVGDKVNKGQLLVTLENTEFVEIQQQYLEVAEQLNYLKSEYERQQTLFDENITSQKNFLKAESSYKSSLAQYNGLQKKLNMMNINPSSVEQGQITSKISLYATIEGFITKVNVNNGTYVSPADVILEIVDTAHIHLELSVFEKDILNIKKEQKITFKIPEASNKTFDAKVHLVGTTVDGTNRTVKVHGHIEDEKRANFIVGMFIEAEIITDSKSSLALPKDAVVEVDGNHFVLVLNQKTENYLFDKVKLELGQQTEDFVEVLNTSDIKDKDVLVKGAFMAMAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK10</accession>
    <name>A0A5C6ZK10_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_08850</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019238">
        <property type="entry name" value="AbiEi_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09952">
        <property type="entry name" value="AbiEi_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="332" mass="39098" checksum="AFBC0B1EBF2E8123" modified="2019-11-13" version="1">MTNFDIFNNAIHNLEKDIPMTWDWKPIVDVIDMVIDGELKMTLNNKTTLYLVEIKKDVKNHQLQNILHYNKEFQNFLLVAEKLFPKVKEELRENNVNYIEGNGNVYINHNDVFLYIDTNKTIKTKKDKGNRAFTKTGLKVIFHFLLNPQLINDTQRDIAAITNVALGNIPLIIHGLLKTNFILRLNKNEYIINDYEALLNKWITEFEQTLKPTLFKQRFRFQNEIQDWRAIQLNQEKTVWGGEPAGDILTNHLRPEKFILYTKETVKDLMLNYRLIPDDNGNIWAYDLFWNGQFNETTAPKELVYAELMIGNDKRSKETANIILNERIKPNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK74</accession>
    <name>A0A5C6ZK74_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_08755</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="185" mass="21675" checksum="C96267DC11E576D1" modified="2019-11-13" version="1">MKTYLKIVTVFVLIASCQSNKKEDNNIVATLEREDTSQNNDMDTSKTQQQFSDFFPKELGEYKLIEVSEATVLSRTITSAFYLKGDNIKNNIVYNLEDGNKKGSSVIKDFEISYKYQNKGEGDTEYIYKERDGYKTIAFLQPEENRNEILFIYRQRFSIVLEGTEQPDKLWSYIKEEDLKKLDNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKE6</accession>
    <name>A0A5C6ZKE6_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Kynurenine 3-monooxygenase</fullName>
            <ecNumber evidence="4">1.14.13.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Kynurenine 3-hydroxylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">kmo</name>
        <name evidence="6" type="ORF">ESY86_05925</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>H(+) + L-kynurenine + NADPH + O2 = 3-hydroxy-L-kynurenine + H2O + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:20545"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57959"/>
            <dbReference type="ChEBI" id="CHEBI:58125"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.14.13.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 4">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from L-kynurenine: step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the aromatic-ring hydroxylase family. KMO subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.13.9" evidence="4"/>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00328"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004502">
        <property type="term" value="F:kynurenine 3-monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034354">
        <property type="term" value="P:'de novo' NAD biosynthetic process from tryptophan"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043420">
        <property type="term" value="P:anthranilate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019805">
        <property type="term" value="P:quinolinate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006569">
        <property type="term" value="P:tryptophan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01971">
        <property type="entry name" value="Kynurenine_monooxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027545">
        <property type="entry name" value="Kynurenine_monooxygenase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4 6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3 4" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD_binding_3" evidence="5">
        <location>
            <begin position="6"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD90272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="465" mass="52597" checksum="E2F0C81C524C4382" modified="2019-11-13" version="1">MKKQQNVLIIGAGLCGSLLALRLGQRGYNVSVYEMRPDLRKTKISAGRSINLAFSDRGSKAIQLVGMGDQVEKLCIPMNGRMLHDEKGDTIMSKYSGREHEYINSIPRGELNALLLTEAEKHENVNIHFNKKCLSVDFEKTTVLFEDYQTKKEFVEDADVIIATDGAGSALRKSYYLANKFLFSFSQEYLTHGYKELSILPAENGGYKTYKNALHIWPRGNFMLIALPNLDGSFTVTLFLSYDEGDYNFNNLTTPEKVTEFFQKEFPDTLELMPNLVDDFFENPTAPLGTVKCSPWHYKGNTLLMGDSAHAIVPFYGQGMNASFEDVVEFDQVLDQNLDSWEAIFETYETNRKKDTDAIADLAIDNFYEMKGHVANPIFQDKRKIEMALEKEFPQDYSSKYSLVTFNEDIGYREAMLRGRAQDKAILNMLSDGLISSSDDLNILLKKITDATNAILEDDKIAGLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKU2</accession>
    <name>A0A5C6ZKU2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Oligosaccharide flippase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_06160</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029303">
        <property type="entry name" value="Polysacc_synt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002797">
        <property type="entry name" value="Polysacc_synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01943">
        <property type="entry name" value="Polysacc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14667">
        <property type="entry name" value="Polysacc_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="156"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="251"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="298"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="323"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="364"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="392"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="423"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="446"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="domain" description="Polysacc_synt_C" evidence="7">
        <location>
            <begin position="352"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD89788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="488" mass="55225" checksum="4E9BC2A33AFB753F" modified="2019-11-13" version="1">MGIVINQSLKNTITTYAGFGLGAVNVLFLYTNFISDQYYGLVAYILSASNIMMPLMAFGAHNTLVKFFTSFKTEHSANSFLTLMLFLPLVLTIPVGIVGYFAHDLIAAALSSKNEIVGAYLWYIFITAFAMAYFEVFYAWVKVQMKTVFGNFMKEVFHRVVAMVLLFMVYFEIIDVHGFLMGLVATYVLRSLLMMLFAFRQRLPVFRFDRLSNLSAIIKYAVLIIVAGSIATLILDVDKVMLNNYIAIEKVAYYSVAVFIATVIAVPQRAMHQILLPLTAQFLNAKDKVALEDLYKRSSLTLCITSGLIFLLIILNINQLYEIIPPEFGGGLLVVFLISAAKLYDNLLGNNNAILFNSDYYRMVIVFGVMLAVLAVLLNMVFIPLYGINGSAMATFISVFVYNTAKLLFVKRKFKMWPFTAETFKWGLLLALLLMVFYFWDFPFHPLANIVLKSVLISIVYLILILRLELSEDISSMLGKILRKNFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL63</accession>
    <name>A0A5C6ZL63_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protease PrsW</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">ESY86_03240</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the protease PrsW family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023596">
        <property type="entry name" value="Peptidase_PrsW_arch/bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026898">
        <property type="entry name" value="PrsW"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36844">
        <property type="entry name" value="PTHR36844"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13367">
        <property type="entry name" value="PrsW-protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016933">
        <property type="entry name" value="PrsW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="11" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="5"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="132"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="166"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="194"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00018997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD90395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="227" mass="25564" checksum="D3A3712BEC56E313" modified="2019-11-13" version="1">MQLLLIAIAPICAVMLYIYFKDKYEKEPKRLLLASFLLGAIGSIIITTLLYYILDILVPIDDAFSIPQQFIKAFLIVGLTEEFSKYIIVRFYAQPKKEFNEPFDGIVYAVMVSMGFAATENVFYVLESGFSTAVVRAFTAVPAHATFGILMGYLMGKAKFSKNRILLNLAGLLIAVTFHGFYDFFLFIDFIPGIWIGAFVSLGIGILLSRKAIKKHQEISHFKPEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL84</accession>
    <name>A0A5C6ZL84_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023085909" evidence="1">
        <location>
            <begin position="21"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="311" mass="35561" checksum="CA63BA9A2143DE69" modified="2019-11-13" version="1">MKPSFYITLLSALFSLQSFAQFDGSKHQSNAGLQLKNRILLVQYQEFKSDNALNYNTFIESALSKIWTLNDSVIYVNNTEFAVLKMKHPKHNNYAYLKYSTYDKVNEFPSGSLVLGLVDEPNSTYFVHVAPFDEKGLNTADLVFGLELLQQKIKRATATPEASKWTDSIIAQPQIIDFKNKTLLIDQTLTSSVVQKSIPQFYKYDFEFATKTRIDEALLNRDPKFIFLRAIPLTTVPTKSKDYSDEAGVQIIDNNIYFSKTYETKIAKSEMRFVNAILQADDRRLLYIGKPKQGDNQVELSFFETLSNALN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLF8</accession>
    <name>A0A5C6ZLF8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">tRNA(Ile)-lysidine synthase</fullName>
            <ecNumber evidence="7">6.3.4.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">tRNA(Ile)-2-lysyl-cytidine synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">tRNA(Ile)-lysidine synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">tilS</name>
        <name evidence="9" type="ORF">ESY86_06340</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + cytidine(34) in tRNA(Ile2) + L-lysine = AMP + diphosphate + H(+) + lysidine(34) in tRNA(Ile2)</text>
            <dbReference type="Rhea" id="RHEA:43744"/>
            <dbReference type="Rhea" id="RHEA-COMP:10625"/>
            <dbReference type="Rhea" id="RHEA-COMP:10670"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="ChEBI" id="CHEBI:83665"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.4.19"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the tRNA(Ile)-lysidine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.19" evidence="7"/>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016879">
        <property type="term" value="F:ligase activity, forming carbon-nitrogen bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01992">
        <property type="entry name" value="PP-ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01161">
        <property type="entry name" value="tRNA_Ile_lys_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012796">
        <property type="entry name" value="Lysidine-tRNA-synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011063">
        <property type="entry name" value="TilS/TtcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012094">
        <property type="entry name" value="tRNA_Ile_lys_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012795">
        <property type="entry name" value="tRNA_Ile_lys_synt_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43033">
        <property type="entry name" value="PTHR43033"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01171">
        <property type="entry name" value="ATP_bind_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11734">
        <property type="entry name" value="TilS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00977">
        <property type="entry name" value="TilS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02433">
        <property type="entry name" value="lysidine_TilS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02432">
        <property type="entry name" value="lysidine_TilS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 7 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TilS_C" evidence="8">
        <location>
            <begin position="346"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="10"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD89820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="432" mass="49140" checksum="58038E9D6E11A4C9" modified="2019-11-13" version="1">MESRLLIAISGGLDSVVLTHLCHKLGLSFALAHCNFNLRGMESDSDEDFVLELAENLDLEIFIESFDTEAYAKNQKLSIQMAARELRYNWFSEVSSSLGFDYILTAHHAGDNLETVLINLSRGTGLKGLTGIPEVNGNIVRPLLPFSREALEHYAHEHKIRWQEDSSNATNKYLRNKLRHEVIPILKDINPELHKNFKTTLEHLNAASEIIDDSIKALSKRAIDSSENAISKYRISELKTLKNPKAYLYELLKDYGFKAWEDVSDLLDAQSGKQVFSATHCLLKDRDYLILTEISEKGQHKEILISAQTETLQTPAGTVTFEKNAEISALTNNTIFVDKDRLKYPLKLRKWGTGDAFHPFGMTGKKKLSKFFKDEKLSLIEKEQVWLLCSQDKIVWVIGMRADERFKVTEQTKHILKIELAVPSKEFGTPKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLQ9</accession>
    <name>A0A5C6ZLQ9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ESY86_07460</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="188"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="9">
        <location>
            <begin position="206"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="276"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="212"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD89614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="484" mass="55518" checksum="327389A4C2E8F549" modified="2019-11-13" version="1">MKLNKLSLRVRIFFAMILLVLIASILIAAVTIFQYNEEAQDYHKQRLERKEFAIVSHINKVIKETTWEVETEKIPLIFKEHIYDIAEIHSLQVNLYDLDGTLLISSKASISNDKDSNCIPAGILNAISNTAAHRYVQKNEKNGETFQASYSYITDGKFKPLAILNLPYLENDDFLNRELTEFLERLGYAYLFMLLIAITLAFLLSKYITRTLKNISEKIKETRLERRNKKIDVSSSSEEITTLINSYNSMIDELEESAVKLAINEREQAWREMAKQVAHEIKNPLTPMRLSVQSFQRKFDPQDPHIHQKVDEYTKTLIQQIDTMSSIASAFSNFAKMPAQQNETLNVVAIVKLALDIFSEDYIEFFAEEPEILVNFDRTQLIRVITNLVKNGIQAIPEDREQPRIHVRVFSEENNVKITIADNGKGISEVNKDRVFEPKFTTKSSGMGLGLGMVKNIVETYHGNITFTTQQGEGTVFTVTFPKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM04</accession>
    <name>A0A5C6ZM04_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetyl-CoA hydrolase/transferase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_06025</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the acetyl-CoA hydrolase/transferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008775">
        <property type="term" value="F:acetate CoA-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003986">
        <property type="term" value="F:acetyl-CoA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006083">
        <property type="term" value="P:acetate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019679">
        <property type="term" value="P:propionate metabolic process, methylcitrate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1080.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026888">
        <property type="entry name" value="AcetylCoA_hyd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038460">
        <property type="entry name" value="AcetylCoA_hyd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003702">
        <property type="entry name" value="ActCoA_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13336">
        <property type="entry name" value="AcetylCoA_hyd_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02550">
        <property type="entry name" value="AcetylCoA_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AcetylCoA_hyd_C" evidence="2">
        <location>
            <begin position="267"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="425" mass="46756" checksum="72443B52D517688F" modified="2019-11-13" version="1">MKKYNPISAEEAVKKIKSKDRVYIQAAAAAPQVLINAMSARHEELRDVEVCHLHTEGEAPYANPDLRDSFHVNSFFIGKNIRHTLKAGNGSYTPVFLSELPLLFKRNIIDLDVALIHVSVPDRHGYCSLGVSVEATLAAIDNAPYVIAQVNKHMPRTHGAGIIHVSEIDAFVESDEHLPEHLMAKPSAIENKIGDHVANLIEDRSTLQMGIGSIPNAVLTRLTNHKDLGLHTEMFSDGVIDLIQNNVINGNYKEVNRGRALSTFLIGSQRLYDYVDDNPFVEMRASNYTNNVAVIKQNPRMVAINSAIEVDVTGQVCADSIGPHMYSGVGGQMDFMRAASLSDGGKAIIALPSTTKKGISRIVPSLNPGAGVVTTRAHVHYVVTEYGVANLYGKTIKQRVKSLVDIAHPDHQERIDKDYFELIMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZME3</accession>
    <name>A0A5C6ZME3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HlyD family efflux transporter periplasmic adaptor subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_04975</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="304" mass="33468" checksum="24192E3CC3B46740" modified="2019-11-13" version="1">MKNHNYILGISILALSLLSCGNGNDKADGYGNFEATEVTVSAENNGKLLQFDVNEGDQLEKNQIIGYIDTIPLGLKREQLEVSKSVISSKSKGVLSQINVLDAKLKTANTNKTRTENLIKDNAGTQQQLDNVQGEINVIKTQIKSVEIQNAPVVNELKSIDVQLKQIDDQIQKSKIINPVTGTVLTKYSEPNEITAFGKPLYKIANLNTMQLRVYISETQLANIKIGQEVSVKIDDADAMKSYKGTISWIASEAEFTPKIIQTKEERVALVYAVKVDVTNDGSLKIGMPAELWITNSNNNNNNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZME6</accession>
    <name>A0A5C6ZME6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF3820 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_04205</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024530">
        <property type="entry name" value="QSregVF_b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40613">
        <property type="entry name" value="PTHR40613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12843">
        <property type="entry name" value="QSregVF_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="76" mass="9150" checksum="F976CFF6584031A8" modified="2019-11-13" version="1">MIQPDQNFLIQLAHTKMPYGKYEGRYLIDLPEYYVVWYHNKGFPKGKLGDMLTQVYELKLNGLEELIRNIKKRYPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMJ5</accession>
    <name>A0A5C6ZMJ5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Chaperone protein ClpB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10 12" type="primary">clpB</name>
        <name evidence="12" type="ORF">ESY86_00870</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homohexamer. The oligomerization is ATP-dependent.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homohexamer; The oligomerization is ATP-dependent.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the ClpA/ClpB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017730">
        <property type="entry name" value="Chaperonin_ClpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036628">
        <property type="entry name" value="Clp_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004176">
        <property type="entry name" value="Clp_R_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018368">
        <property type="entry name" value="ClpA/B_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028299">
        <property type="entry name" value="ClpA/B_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17871">
        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02861">
        <property type="entry name" value="Clp_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81923">
        <property type="entry name" value="SSF81923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03346">
        <property type="entry name" value="chaperone_ClpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51903">
        <property type="entry name" value="CLP_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00870">
        <property type="entry name" value="CLPAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00871">
        <property type="entry name" value="CLPAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 9" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5 10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="Clp R" evidence="11">
        <location>
            <begin position="3"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="410"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00026057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TXD91172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="869" mass="97858" checksum="D1051967D4B38718" modified="2019-11-13" version="1">MNFNEYTIKSQEAIQQAQQLAQSLGHQQIENEHLFKSLFDVDENVLPFILKKLNVNINMLQLAVDKQLESYPKVSGGDIMLSRELNKTLNEASIIAKKMNDDYVSVEHLILAIFKSNSKIAQMLKDQGVSEKGLKAAIEELRKGDRVTSQSQEDTYNSLNKYAKNLNQLAKDGKLDPVIGRDEEIRRILQILTRRTKNNPILVGEPGTGKTAIAEGLAHRIVDGDIPENLIDKQIYALDMGALIAGAKFKGEFEERLKAVIKEVTNSDGDIVLFIDEIHTLVGAGGGQGAMDAANILKPALARGELRAIGATTLDEYQKYFEKDKALERRFQKVMVNEPDTESAISILRGIKEKYETHHKVRIKDEAIIGAVELSQRYITNRFLPDKAIDLMDEAASKLRMEINSKPEELDVLDRKVMQLEIEIEAIKRENDESKLRSLRADLANLKEDRNEIYAKWKSEKEVVDNIQTAKANIEEFKLEAERAEREGDYGKVAEIRYGKIKEAQEELEKLQKELQENQSESALIKEEVTYDDIAEVVAKWTGIPVTKMLQSERDKLLKLEDELHKRVVGQEEAITAVSDAVRRSRAGLQNPQKPVGTFLFLGTTGVGKTELAKALAEYLFDDENAMTRIDMSEYQERHSVSRLVGAPPGYVGYDEGGQLTEAVRRKPYSVVLLDEIEKAHPDTFNILLQVLDEGRLTDNKGRVADFKNTIIIMTSNMGANIIQERFEATKDVESAMAAAKVDVIALLKQTVRPEFLNRIDDTIMFTPLTKENISKIVGLQLKSVKKMIAKQGIVFDATPEAVSYLSKKGYNPEYGARPVKRVIQKEVLNELSKEILSGKVTTDSIILLDAFDEKLVFRNQDHEVSEEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMN2</accession>
    <name>A0A5C6ZMN2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016702">
        <property type="term" value="F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012864">
        <property type="entry name" value="PCO/ADO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07847">
        <property type="entry name" value="PCO_ADO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="206" mass="24041" checksum="F45E23E69822CA55" modified="2019-11-13" version="1">MDDFKRREFIKLSTMAFAGIALQFSNVSAYALNANGQNGFLGSNPEMNWDAFISKIQTLAKTQHLKSWNQSAYLTQVKALMDKCKFPEFQKVEKAFKEYKNNKPDWFEHELLHQEIDFQVSLLQFEKGEYIPHHDHPEMCGIINMVTGNALVKNYSLEKHLDTERTVANGENELLYKSCVIKEVQTKFYYQIKLAYLWLQKVISIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMP1</accession>
    <name>A0A5C6ZMP1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_05535</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="127" mass="14918" checksum="07F918CDAD973A56" modified="2019-11-13" version="1">MSKAQVNEIKEGLQHFHGTEMFYQIPLLRTRFTDGLKYLSEVAECFWLITDTSVIAKSLMNRSEFVTIDFKRLPKEKQDYSGYEAEIIYSDGNDNILEKHGYRATDFPLDELRLFFVNDTLMLPSEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMQ0</accession>
    <name>A0A5C6ZMQ0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DoxX family membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_04275</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032808">
        <property type="entry name" value="DoxX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07681">
        <property type="entry name" value="DoxX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="45"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="78"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="120"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="148"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD90591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="364" mass="41512" checksum="2006C8C60B947505" modified="2019-11-13" version="1">MRIIVNICRILVGALFIFSGFIKLNDPLGFSYKLEEYFSYDVLNLPFLMPYALGLAIFVVVFEVVLGVFLLIGYKPKFTVFSLLAMIVFFTFLTFYAAYFEKVKDCGCFGDFLKLTPWESFTKDLILLTLIIVLVIGRRFIKPVFSRFGLTVAALLSFIACLGFGYYVLMHLPALDFRPYKVGDNLLENMELPEDAQMAISDYTWHYTEGGEEKTLTDRGRGPKSYDKIISVDTKVIQEADVPKIQDFSIESEDEDLTEAFLNKDKLVIVVAYSLEKAETAGWKDIKVKTDELKKKGFTVIGMTASGDDKKQEISEAYDLDFEFYLCDEKVLKTIVRSNPGLVVLKKGTVIQKVHWNDIDDLEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMS8</accession>
    <name>A0A5C6ZMS8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Efflux RND transporter permease subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_04435</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="334"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="431"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="463"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="527"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="856"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="881"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="953"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="982"/>
            <end position="1010"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1029" mass="113738" checksum="B064F280DCC96477" modified="2019-11-13" version="1">MSLSTLSIKRPVLTIVMNLTLVLFGIIGFTYLGVREFPSIDPAQISVSTSYSGANADIIESQITEPLEKSINGIDGIRNMTSSSNQGSSRINIEFNLDKNLEEAANDVRDKVSQAVRSLPQDIDAPPVVSKADADSRAIISMTVQSDNKNILELTDYADNVLAQRLQTIPGVSSVQIWGQRRYAMRMWIDPIKLASYGVTVAEVREALLSQNVELPSGKLTGANTELTVKTIGNLSNEEEFNDIIITSEGGRVVRFSDVGRATLEAENMETKLSDSGQPMVALAIVPQPGANYVAIADDFYAEFEKLKEALPEDFKLNVVIDDTLFVKRAITEVVETLGISIVLVILVIFFFFRNWSMALRPLIDIPVSLIATFFIMWMFGFSINVLTLLAIVLATGLVVDDGIVVTENIYKKVEEGMSPIEAAIKGSNEIFMAVISISVTLAAVFLPVIFLEGFVGRLFREFGIVIGAAVLISAFVSLSLTPMLNAYMMKPGKQNQTKFYRVTEGYFVKMNKAYASSLGKFMKNKWWSFPVLIVCIVMIGVFYSLLQKETAPYDDRSYIRLSVSAPEGASYDYMDRFMNEITELINDSIPEKKVSLIITSPGWGSSSVNSGLAIISLVDPSDRERSQKEIAEDLTKWTRTFENARTSVSESPTIAVNRRGGMPIQYIVQAPNFEKLKEKIPLFMEEAENNAVFANTDVDLKFNKPEIYVTIDRNKAKSLGVSVLDVAQTLQLALSGQRFGYFMMNGKQYQVIGQFDQKDRNAPMDLKSMFVKNDKGELIQMDNLVTTEEQSSPPQLFHNNRYMSATVSASLAPGMSINDGIEAMESIRDKVLDDSFTTDLGGESRDFVESSSNTLFAFGLALLLIFLILAAQFESFIDPFVIILTVPMAVAGALFSLWLFGQTWNIFSQIGTIMLIGLVTKNGILIVEFANQLREEGLSKHQAIMKASESRLRPILMTSLTIALGALPIALSLGAASTSRIGMGVVIIGGTMFSLVLTLFVIPSIYMLWSREKKKRPEFDKIDSYEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN45</accession>
    <name>A0A5C6ZN45_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_01390</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="5"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD91269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="128" mass="14705" checksum="AACE12A1A5F6FE2E" modified="2019-11-13" version="1">MDHNYFMIIDDDEDDRFFFKDALTKMPSAVKFIEANGGQEALELLRTGEHMPHYIFLDINMPRIDGRECLKLLKSDAKLKHIPVIMYSTSFSQESITEFHKLGASTCLKKPTDVTKLPAQIIEVIKDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNJ4</accession>
    <name>A0A5C6ZNJ4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AsmA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_02695</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032712">
        <property type="entry name" value="AsmA_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13502">
        <property type="entry name" value="AsmA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AsmA_2" evidence="1">
        <location>
            <begin position="575"/>
            <end position="800"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="894" mass="97574" checksum="993CE0B0F32DD91A" modified="2019-11-13" version="1">MKKVLKVLGISILAILLLLIIIPFAFQGQIKDMVKKFVNQNLNAKVEFSDVSLSFLRSFPQAHVTVEDLLITNFAPFEGETFMSAKDIAFTMSIKELFKNADEDPIVVNSIAIDEALLTLKTDAFGNVNYDITKQPEASGATQTVDTANSSFKFDIEKYTIDNSAVTYLDAVSNTQLYITELNHQGNGIFSVEKSELDTKTNANVSMTIDSTQYLNNNKIKLDALIGLDLEQQKYTFMDNKGYINQLPLTFNGYVQMLDEGQMIDISFENPGSSFKDFLAVIPEEYSKNIENVETSGDFKVSGLIKGKITETTIPNLDISIKSSNASFKYPDLPKRVSNISIDTEIKNTTGNVDDTYVNINALDFMIDQDRFKSSATIKNLTANMLVNANIDGVLNLANLSKAYPIDFDKELSGILKAKLNMAFDMDAIEKNAYERIKANGTMSVSDFVFSSEDLLHPIQINTADLNFNPSTVTLNNFMAKTGSSDFSATGTINNLLGFLLSNKQLQGTFNLSSNTFVLNDFMTQDVAAAENPSEASAPASKTSSAKDASIKIPDFLDCTINANAKTVIYDNLTLKDVEGKLTIKDQEVTLQNLTSSIFKGILAVTGRVSTKTDTPTFNLDIGADGLDISQSFQDMDLLRNLAPIAKFVEGKLNSVISLQGTLNNSFSPNMNSISGSASADLLTTQVQPQAGSALSKLEGALNFIDFSQLDNKDIKVDLNFADGKVNVKPFNLNYKDIGIAVSGSHGFDKSLNYNAVFNVPAKYLGSEVNRLIGKINENNVNNLTIPVTANINGSMTSPQITTDLTSGITNLTQQLIEIEKQKLIGQGKDKVKDLLGGLLNGNQTNTTTDSTKTVTTDSTKVKTDPVREGVKDILGGLLNKRKKKADSTKSKQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNN2</accession>
    <name>A0A5C6ZNN2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carboxypeptidase-like regulatory domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_02985</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014755">
        <property type="entry name" value="Cu-Rt/internalin_Ig-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="520" mass="60591" checksum="2F7418A19B1B192D" modified="2019-11-13" version="1">MIYCTKSVHFEIKKIIFLAIIISYCVIGNSQNGDYLFCKIIDQETQDPVVFATVQIKSENLGVIADEHGFFRLPMNTKAERKFIILSSIGYKTNEFQAGDFSSDKVNILKLAPQVEALDAVNILVNRNKKEEPYISAEEIVKKAIFNIRLNFPTEPHSYIAYYRDYQLLNNQYFNLNEGIFEDFDAGIQTHKLKYKDNKTALYSFEQNSDFNRDSVLTVPYNQNDNKFMKNATVSGLGGNELSILNIHNAIRNYELQSFSFIDVFKNDFLHNHKFRIKSKVYQDNRTIYKLAFYALENVTGIYNSANGFIYIDSKSFAIHKLEYYGYNKKDEDPFYSLTVEYKPQDSKMYLNYISFQNKFKAKSAFDFRIDSMGFDANKNEIKLRFSKKIDQKTLKRKNQIKLIFKNEKLKVTSYKFLDEKTISLKIAGGSAVSNTDLAKDLEVKIRKIKDVAGRELNEIIFLDANQYRELFVQRVHIDKEPSPDLFYINKVDQLHNAKQNSNPKIDKTYWINSPLLENN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNR5</accession>
    <name>A0A5C6ZNR5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptide deformylase</fullName>
            <shortName evidence="2">PDF</shortName>
            <ecNumber evidence="2">3.5.1.88</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Polypeptide deformylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">def</name>
        <name evidence="3" type="ORF">ESY86_04555</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H2O + N-terminal N-formyl-L-methionyl-[peptide] = formate + N-terminal L-methionyl-[peptide]</text>
            <dbReference type="Rhea" id="RHEA:24420"/>
            <dbReference type="Rhea" id="RHEA-COMP:10639"/>
            <dbReference type="Rhea" id="RHEA-COMP:10640"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:49298"/>
            <dbReference type="ChEBI" id="CHEBI:64731"/>
            <dbReference type="EC" id="3.5.1.88"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="2">Binds 1 Fe(2+) ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the polypeptide deformylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.88" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042586">
        <property type="term" value="F:peptide deformylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00487">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.45.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00163">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023635">
        <property type="entry name" value="Peptide_deformylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036821">
        <property type="entry name" value="Peptide_deformylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10458">
        <property type="entry name" value="PTHR10458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01327">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004749">
        <property type="entry name" value="Pep_def"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01576">
        <property type="entry name" value="PDEFORMYLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56420">
        <property type="entry name" value="SSF56420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00079">
        <property type="entry name" value="pept_deformyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="2">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="196" mass="22585" checksum="39295B40F021D57E" modified="2019-11-13" version="1">MTLAIVAYGDPVLRKKADPIAKDHPNLDEIIENMKETMYAAFGVGLAAPQVGLSIRMFLVDTSPFAEDEDFSIEERAQLKAFNRTFINAEIMEEEGDEWAFNEGCLSIPDIREDVFRQPKIKIKYQDENFKEHVEEFDGLIARVVQHEYDHIEGILFTDKLSSLKKRLIKGKLSNISKGKIDVDYRMRFPSVKKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNT1</accession>
    <name>A0A5C6ZNT1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_03160</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="235"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="274"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="4"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="316" mass="36281" checksum="8060A364FB52E7B0" modified="2019-11-13" version="1">MNISVVIPLLNEQESIIELHDWIANVMQSNRFSYEIIFIDDGSTDHSWQNIMQLSHQNDNVKGIKFLKNFGKSQALHAGFAKAEGDVVITMDADLQDNPEEIPELYNMIVIEKYDLVSGWKKKRYDSVISKNLPSKLFNWAARKTSGVELHDFNCGLKAYNKNVVKNIDVNGEMHRYIPVLAKNAGFLNIGEKVVQHQARKYGVTKFGMERFVNGFLDLLTIWFISRFGRRPMHLFGALGVIMFMIGVGFSIYLGIDKLIFNPTGRLITQRPQFYIALVTTIIGTQFFVAGFLGEIILRNKREHHRYLVKQELNFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNX4</accession>
    <name>A0A5C6ZNX4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_00175</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="114" mass="13337" checksum="6035B258C08E9CDF" modified="2019-11-13" version="1">MTVQHPKQSIRLAILVLAFSLVLPSAVKFTHAFAHHQHEVCYGEAQSHFHNINLDCDFYKFKLNNSFYVPLVNYELQDDFRQQPLKSKYYTFLKSHQQLTSYLRGPPCLVSYSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPH6</accession>
    <name>A0A5C6ZPH6_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thioredoxin reductase</fullName>
            <ecNumber evidence="1">1.8.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">trxB</name>
        <name evidence="3" type="ORF">ESY86_01240</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[thioredoxin]-dithiol + NADP(+) = [thioredoxin]-disulfide + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:20345"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.8.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.9" evidence="1"/>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004791">
        <property type="term" value="F:thioredoxin-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019430">
        <property type="term" value="P:removal of superoxide radicals"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005982">
        <property type="entry name" value="Thioredox_Rdtase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01292">
        <property type="entry name" value="TRX_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0274">FAD</keyword>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="1 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="2">
        <location>
            <begin position="9"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD91241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="325" mass="35538" checksum="2D23D7C2CE5CB0C1" modified="2019-11-13" version="1">MSDQIEKVKCLIIGSGPAGYTAAIYAARANMKPVLYQGVQPGGQLTTTNEVENFPGYPDGITGPEMMIELQKQAERFETDVRNGWVTKVDFSGDIHKVWVNDTKEIHCETVIISTGASAKYLGIDSEQKYLKLGGGVSACAVCDGFFYRNQEVVIVGAGDSACEEAHYLSKLCKKVTMLVRRDEFRASKIMSARVKKTENIEILYNTETDEVLGDGQVVTGVRAFNNQTNEKHVIPATGFFVAIGHTPNTDIFKDYLKMDETGYIINKPGTAKTEVEGVFVSGDAADHVYRQAVTAAGTGCMAALDAERYLAAKDADFEFVTPMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPL1</accession>
    <name>A0A5C6ZPL1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF1599 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_04270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011630">
        <property type="entry name" value="DUF1599"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07659">
        <property type="entry name" value="DUF1599"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1599" evidence="1">
        <location>
            <begin position="22"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1599" evidence="1">
        <location>
            <begin position="115"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="183" mass="20896" checksum="E6E0ED1A40D32082" modified="2019-11-13" version="1">MKDTSKQYDAVIAKCRSLFVNKMADYGSAWRILRLPSLTDQIFIKAQRIRGLQQNEVRKVDEDEVSEFIGIINYSTMALIQLDKGVVEQPDLDLAEAEQLYDQKIAIAKQLMLDKNHDYGEAWRDMRVSSLTDLILQKLLRVKQIENNAGKTIVSEGIEANYQDMINYAAFALIHLNQDGEIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPN1</accession>
    <name>A0A5C6ZPN1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_04375</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="14"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="80" mass="9176" checksum="5ED5F0EF89C11484" modified="2019-11-13" version="1">MKDWNRNNTIAEFVRNSRKASKMTQLELSDLTGVGIRFIRDIEQGKPNLMTAKINQVLLFFGQELSPRPISDATRRNLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6Z9V7</accession>
    <name>A0A5C6Z9V7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000080">
        <property type="protein sequence ID" value="TXD86222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="135" mass="15952" checksum="FC5D2CD399390345" modified="2019-11-13" version="1">MKIKFNENEKSIEIEDGLKMQYLLMKISLVFTLINSVLFPFFVLEKNQMEWMGFIWIILGIFSIVMLTYQLLKKTASEKINLSEINSLTEKRVFGRKRFSLKLKNGKLRDLMEMKNESDITETKELFKNIGIETN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZA80</accession>
    <name>A0A5C6ZA80_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Acid protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19270</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000038">
        <property type="protein sequence ID" value="TXD86795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05483">
        <property type="entry name" value="retropepsin_like_bacteria"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034122">
        <property type="entry name" value="Retropepsin-like_bacterial"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="SSF50630"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="147" mass="16181" checksum="2FDB480BF5299299" modified="2019-11-13" version="1">MDTTLKNFLLDKGYTKVKLQLTKTNHFEVKAIINGVKGLFILDTGASNSCVGFEAIKTFKLVAEDSEIKAAGAGASDMLTQMSNKNEIKIGKWKNKKVALVLFNLSHVNEALINHDAQPVDGIIGADILKKSKAIIDYDKKQLYLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZA93</accession>
    <name>A0A5C6ZA93_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000069">
        <property type="protein sequence ID" value="TXD86322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022912715" evidence="1">
        <location>
            <begin position="20"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="303" mass="35873" checksum="79221F0FDA21AAD8" modified="2019-11-13" version="1">MKKISFIILTLVFNTMLNAQNVDFGNFPSENNDKKPMLTSNLLKSLNWEKLKESSNSNEGHYTYERKDSLLFEYKYVQQGLVADFKIISFNDKVLEYQSQISNTSKETNTNYFDKKLWLEYAHSYLPNLADSLKLSVNESKRILKAYYELLGVGTYDEYGWICEYSTVGRATDRRIAVIELLGREELLWQLIDYPNIHVQLYVADALIYSDFRNKKMIEEYKENRKYKTAREMIKYLKDELLTKEEWKKIYEIRDSNQKVNTCKSGTGSYKIYENNTSELLSEQGISEIPERYEELRKLGYLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAV7</accession>
    <name>A0A5C6ZAV7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_20375</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000068">
        <property type="protein sequence ID" value="TXD86339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="532" mass="57617" checksum="ECB227C2A7A02EA9" modified="2019-11-13" version="1">MKSKIHLLTILITFCIYNTYGQITTTLDEVYVNGQTSVTNCGTIDFETTENNTLTFYYTLTKTSSSTGEGFLKIKLKYNSSSNGAERGNQYITSNLWNSNQYVHTIATNIDASEVQVNGSSIYLEFTEVSSPFDYYNSCEHSIIKTPVPSFSLTPTNTTVSCESTSVKNFTVTPSNIPNGATVSYQWNVGNGWEDTNGNPISNFTTTSTFVQLRPYQYPPNNVSVTPILNGVSYPQLTSTVSLGTFNPFINIVGDDYVCSSGVYTLDNISSFNNVTVQSVNSSNTSIATASYNATTGEITVTKVSDGIITLSAVLQNSCNQTVTKTKENIQIGIPSTVFNATITGNDSVCQGQNYTYALSGANHPCVNGIVWSVTSNLNIVSQSSNTIIVSKNPFSTEYAGEITASILGSTVEVNKGVWVGTPSNDGLVIQKIGSYDLYAGQWSKLRARYIPLTYVSNDPLNITFEWQIPNSMIRNYADTAYKDVKPRSSGQLNIGVRVNCECGNGEWEYRLFDVAGGNGNGGGVLTPVGGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZB77</accession>
    <name>A0A5C6ZB77_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000114">
        <property type="protein sequence ID" value="TXD85890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022959894" evidence="1">
        <location>
            <begin position="25"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD85890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="140" mass="16242" checksum="CAA33522A025D488" modified="2019-11-13" version="1">MKNKPLKLVTFIVIAFLVSCSANKELIGKEKTEFGDVKFYVENDLKNSYYKKRVLAIFQNSIFYSFYSNEIVKTKKNNEGLIYTLTFGEIPKELNQPRYFQKLSRIDSLILTKGDKVLDSLEWNNYKKSKGASGFIIEVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBG8</accession>
    <name>A0A5C6ZBG8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">D-alanyl-D-alanine dipeptidase</fullName>
            <shortName evidence="3 4">D-Ala-D-Ala dipeptidase</shortName>
            <ecNumber evidence="3 4">3.4.13.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_19340</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 4">Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 3 4">
            <text>D-alanyl-D-alanine + H2O = 2 D-alanine</text>
            <dbReference type="Rhea" id="RHEA:20661"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57416"/>
            <dbReference type="ChEBI" id="CHEBI:57822"/>
            <dbReference type="EC" id="3.4.13.22"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the peptidase M15D family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.13.22" evidence="3 4"/>
    <dbReference type="EMBL" id="VORO01000039">
        <property type="protein sequence ID" value="TXD86776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016805">
        <property type="term" value="F:dipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01924">
        <property type="entry name" value="A_A_dipeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000755">
        <property type="entry name" value="A_A_dipeptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009045">
        <property type="entry name" value="Hedgehog_sig/DD-Pept_Zn-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01427">
        <property type="entry name" value="Peptidase_M15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF026671">
        <property type="entry name" value="AA_dipeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55166">
        <property type="entry name" value="SSF55166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3 4" id="KW-0224">Dipeptidase</keyword>
    <keyword evidence="3 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 4" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3 4" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="205"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="3">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR026671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD86776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="226" mass="26476" checksum="CA3F84F4302A3421" modified="2019-11-13" version="1">MSHKIFKFLFICFASTLAIQDEAQLPEDFVYVKDVIPDLDVELRYFSANNFVGDTIDAYKADKLILTKPAAEALKKVQSDLQDQNLCLLVYDAYRPQQAVNHFMRWAKDLNDTINKPEFYPEIKKRNLFNKGYIASRSGHSRGSTVDLTLMDRNTDEVLDMGSPFDFFGKASWTAHPNLTAQQKNNRNLLLTAMQKHNFRNYPKEWWHFSLRWEPFPNTYFDFPIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBP6</accession>
    <name>A0A5C6ZBP6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000035">
        <property type="protein sequence ID" value="TXD86894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006744">
        <property type="term" value="P:ubiquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007715">
        <property type="entry name" value="Coq4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05019">
        <property type="entry name" value="Coq4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="184" mass="21447" checksum="FED9FF3DC8715DF2" modified="2019-11-13" version="1">MKALREQFIEWLFKHSQNGYTGLFKHHASWGISRTDLLRYPKDSFGRHLGLFLDKHDFELIAKVERHDAYHTLTGFGTQVADEIALQWLCFGNGKRSPYLYGAIILGTVILPDYWAYYIASYKLGKNANPFHQLDYKKLLQLKLKDLRAAFFSKRQQIQLTQLKHTTHSAILKSNQTPRMENST</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC93</accession>
    <name>A0A5C6ZC93_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">IS1595 family transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20425</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000071">
        <property type="protein sequence ID" value="TXD86302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024445">
        <property type="entry name" value="Tnp_ISXO2-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12762">
        <property type="entry name" value="DDE_Tnp_IS1595"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS1595" evidence="1">
        <location>
            <begin position="10"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="147" mass="17035" checksum="936DE10D42D8BEC0" modified="2019-11-13" version="1" fragment="single">SNVMVMAESTVLEDIDTGKVERQCRYFKAKVLDDHKAEGTDQTFVDAIDGERTIVFTDKCTSYVNIADYVEIHVTEKSNGQTTKETLKWVHIAISNAKRNFTGTYHKIKKKYLQLYLNEFVYKLNRRYFGERIFDRLLIASITANGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCE9</accession>
    <name>A0A5C6ZCE9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Response regulator transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_19265</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000038">
        <property type="protein sequence ID" value="TXD86794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="4"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="138"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD86794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="211" mass="23975" checksum="070DA8B0D05FEF29" modified="2019-11-13" version="1">MPDSIIIADDHPLILKGLSDFLLEKKYNVLASAKNGREAYTLIKAHTPEIAILDIQMPFLTGLQVAKKCKEDGIETRIIIITFEKSKDVYDQAKSLGIYGYILKEFAIEELEHCISDVMEERSYFSPELLKHLEIKETPNILKTLTVTELKVLHLVAKNNTAKEIGLNLFISDRTVEKHKSNIREKLKLSSNAQSIAIFAKEHESFLAEYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCL2</accession>
    <name>A0A5C6ZCL2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SdpA family antimicrobial peptide system protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17435</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000026">
        <property type="protein sequence ID" value="TXD87343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023902">
        <property type="entry name" value="Sporulation_SdpA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17418">
        <property type="entry name" value="SdpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04034">
        <property type="entry name" value="export_SdpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="176" mass="21067" checksum="71A0D386C1A2CA73" modified="2019-11-13" version="1">MISWLMIFMKSYKKTTQYLLNMIVIILVFFMLIIFSKDNVINLNANTLRIISPQGYAFFTRDPKEPQLFIYKLEERKIIEDLSKNSTTSDMLFGLSRKNRRQSLEMNEIFPKLIKWEDYNSLEDLKHIVPDTLSIKSKDSKKLTGQFLIIREKRIPWAWASNLKTPQRKFKFIYLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCP3</accession>
    <name>A0A5C6ZCP3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_20275</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000062">
        <property type="protein sequence ID" value="TXD86420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="638" mass="69424" checksum="861788F569DAFB5B" modified="2019-11-13" version="1">MENDSNLDHDTNLYISHDAPHQGAHLPLGILHMGRHVVNEFIQTPLGNISIPINGAGSYGLATIDDLLDAPAVNQILINNVDTNGNRTNTAHNTWQSELQTMGYPQQTRNIALSNASHCASGQGLASNEELVTVTGEGGTSVLTSIIELLFINFDPLIGIALNDTSATLLGFLPGNSNLDLEFRANAFPSSGTARIYKGRLTYEKRFLWLIPITRTIFNKSKNSESGDKFIDNYPGGVTPNGLAIAESDDEDNWFYNYDYNININLNFDFIPVTSALDVGSGNTNLDDNDYFRQYTSANPPTGDRSIPFVNFATSSNQNNNLNAEHISFNRRNGDWLAEELDADANIDLFNCTPFCTNTEITGDDVLCTTGIYSVTDLATTVNWTVIDPDNLVSFNTNGNEITLNQLNPNNFGIVTLNVIYGNQRCGFVTATKDIEVGILPDNLNNASLTGATSICGSQYYTYNISGFSHPCVTSINWTVSPNLTIVSQNANSVTVTNNPFNDQYAGLITANLPNSSFVIEKGVWVGVPSNDGLTIQKIGSYDLAVGQWTKLKANYIPLLYPANDPLNVTFEWQIPYSAIRNYPDTAYKDVRPNNSGQLNIGVRAVCDCGNGEWKYRMFNVSGGNGNGGGVLTPVGGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCP9</accession>
    <name>A0A5C6ZCP9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17655</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000027">
        <property type="protein sequence ID" value="TXD87260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="106" mass="11825" checksum="E417F2942C3833D1" modified="2019-11-13" version="1">MSKPSPKPPTKSAETESSETKVLKNQNFQESTLCCWKTPTKAFAFKSKLSFSGCVLRLSEAECSESQCPPLLVFSTNSYPNVHSVSLAFNETRRARNFRNQSAKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDA5</accession>
    <name>A0A5C6ZDA5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19420</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000040">
        <property type="protein sequence ID" value="TXD86743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="SSF52490"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="506" mass="56921" checksum="E398F6FB4D07A719" modified="2019-11-13" version="1">MAKLYIFGIGGTGARVIKSLTMLLASGVKTNFDIVPILIDPDSAGGDLNRTIKLLRDYQNIHKTVDGYEQNNFFKNKISTLSDIVTEQGGGAKVFDGFRFELDGIQNDRFKDFIDFNSLDANNKNLVKLLFSEKNLDADLGVGFRGNPNIGSIVLNQFTKSEVFQSFADSYEADDRIFIVSSIFGGTGAAGFPLLLKNLRKGKVGGKNYEHLKNSRIGAISVLPYFKVKQNDNSQIDSHGFITKTKAALHYYARNISGNNSINSLYYIGDSAENTYENIEGGTNQKNDAHFIELASALSIIDFAHTEDIYLETKNGNASNPTYKEFGTKAARQLSFNDLFDGTKNSIINNLTEYFYFNLFLKDKMTWAIDKNYPFVSEDGAKFDKNFIQQSFYKNFLSDFNKEFRIWLAEVFRNQISFAPFAINPIANEKNEITDFEINTSNIFTLARGIPERKNKFNPFAKNNYELFVSELNVASHKLGDAPNPQKRFMGVFSQGTKALVNKKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDC4</accession>
    <name>A0A5C6ZDC4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Family 43 glycosylhydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_16085</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glycosyl hydrolase 43 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000021">
        <property type="protein sequence ID" value="TXD87688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.115.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000421">
        <property type="entry name" value="FA58C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006710">
        <property type="entry name" value="Glyco_hydro_43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023296">
        <property type="entry name" value="Glyco_hydro_beta-prop_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00754">
        <property type="entry name" value="F5_F8_type_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04616">
        <property type="entry name" value="Glyco_hydro_43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="SSF49265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75005">
        <property type="entry name" value="SSF75005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50022">
        <property type="entry name" value="FA58C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F5/8 type C" evidence="3">
        <location>
            <begin position="312"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="4">
        <location>
            <begin position="476"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD87688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="560" mass="64128" checksum="A5AE4B5E11A64C4F" modified="2019-11-13" version="1">MSHYRARNNVSYRSGADPAVVNFKGRYYMFVTRSHGYWASDDMSNWTFIKPQSWFFNGSNAPAAAVRDGKIILLGDPSGRGAVIETNNPELGDWKTNYAVINVPGGVQDPNLFVDDDNKVYLYEESSNKWPIHAIELDADNYFIPMGEQVVLFNLDPEKHGWERFGQDHKSDLKPFIEGPWMVKHGDTYYLEYGAPGTQWNVYADGVYTGKSPFGPFEYAPYNPISYKPGGFLKGAGHGSTVQDNSGNYWHYSTMAISVNYKFERRLGMYPAGFEDDGQMYVNTAYGDYPHYLPGTEVERHKERFTGWMLLSYNKPVTTNSGLVEKDVNVVDESEGGYMQAQIKDFNINKINDEEIRSYWVSEANSDSIYVEMDLLKVMDVKAIQINFQDFNSEVFGRPDGIKQQFVIEGSMDGTTWETILDYSKNERDMPHAYLELETPAEARYIRYNHVYGYNKYLAISELRVFGNGKEAKPAPPANFKVARQKDRRNTDLTWDKVEDATGYVIYWGIAKDKLNLSALMYDAPNYELRALNTDQAYYYQVETFNENGISAKSEILYTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDG4</accession>
    <name>A0A5C6ZDG4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CIA30 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_16190</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CIA30 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013857">
        <property type="entry name" value="NADH-UbQ_OxRdtase-assoc_prot30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039131">
        <property type="entry name" value="NDUFAF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13194">
        <property type="entry name" value="PTHR13194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08547">
        <property type="entry name" value="CIA30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CIA30" evidence="2">
        <location>
            <begin position="4"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="160" mass="18720" checksum="071CFAA98BB52AF7" modified="2019-11-13" version="1">MTLFDFTPNADVSNWKIIDDVVMGGRSNGDFKLNAKGYGEFYGRISLENNGGFSSLRYNFKTKSSSDFSKFILKIKGDGKNYQFRVKTNRSDDASYVFEFETTKEWMTIDIPFNKMQPQYRGRKLDRPNYPGKEMEEVTFLIGNKKEESFMLLMDWIKLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDL3</accession>
    <name>A0A5C6ZDL3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19505</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000041">
        <property type="protein sequence ID" value="TXD86727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000801">
        <property type="entry name" value="Esterase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00756">
        <property type="entry name" value="Esterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="366" mass="40054" checksum="51A3327B7F56E44F" modified="2019-11-13" version="1">MKTYIKLFLLIIGVNAYSQTLIDTIYQQPITATKAFQGQFGSATLQIDDAGSDGLITKPLIIAEGFDSGLLGAENEFGENQLEDFIDDIQDANSLDLAILLTGDTEFDFGDQDYDIIYVNWDSPRAHLQLNAFVLEEVITWVNQEKEADADQNVVLGQSMGGVIARYALANMEQDNDPNTNHDTKLYISHDAPHQGANIPIGIQYFARHLADQFIGTPLGDFSFEVSDDSEASIQEINALFNEPGTQQLLSNYITPNFSHSTAAFDAFQADLQSKGYPTLTRNIAISNGSHCANTQEYDYNASLFRMNGNARTGVLTDLLGSFLGIADDIALAVIFDEPALLLGVLPGSSRFNLDFNAKALPRANN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDR0</accession>
    <name>A0A5C6ZDR0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PIG-L family deacetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17265</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000026">
        <property type="protein sequence ID" value="TXD87312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003737">
        <property type="entry name" value="GlcNAc_PI_deacetylase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024078">
        <property type="entry name" value="LmbE-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12993">
        <property type="entry name" value="PTHR12993"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02585">
        <property type="entry name" value="PIG-L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102588">
        <property type="entry name" value="SSF102588"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022664304" evidence="1">
        <location>
            <begin position="21"/>
            <end position="841"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="841" mass="94856" checksum="520E01336953AC33" modified="2019-11-13" version="1">MQRILRFLVLFFMTTTLAIAQQPKKLSSSEIYESIKKLNFLGSVLYLAAHPDDENTRLISYMSNEVKARTAYLSLTRGDGGQNLVGPEIRELLGLIRTEELLAARRIDGGEQLFTRANDFGYSKHPDETLAIWDKNEVMSDVVLAIRRFQPDVIINRFDHRSPGSTHGHHTSSAMLSVEAFDLANDKNAFPEQLKLVDTWQTKRQFFNTSWWFYGSQEAFDEADKTNLLQIDTGVYFPSSGKSNPEIAALSRSQHKSQGFGSMGSRGEQLEYIELINGDLPQDKSNIFEGIDTTWNRVKGGKAIGDILTEVQNNYDFKNPSASLPNLMRAYKLITNLENTHWKTVKTKEIKNIITACAGLYLEASAASNFATPNETVALNIEAINRSTSNISLTSIKIPNGVEVSKHLKLENNAGFEFKESFKISPDEAFTTPYWLTKKGSLGMYKVEDPKLIGKPRTPRNLKVTFNLNIENSPIDIEKTVIYKTNDPVKGEVYKPFDIIPEASASISEKVIILNSDAQRDIEVLVKSGRNDLEGYVELAYPKNWKVYPQKQKFEITYKGETQSLVFTVIPPKEQSEGLISPIVHVGDKTYTKELVEMEYDHIPFQAVLLPSESKIVRLDIKKRGENIGYIEGAGDVVPESLRQIGYNVSLLKPEELSAENLQKFDAVVVGIRAYNTLDALKFKQQQLFDYVAQGGNLIVQYNTNRGLVTEELAPYTLQLSRDRVTDENAKVTLLATESEVLNQPNKITKADFEGWTQERGLYFPDEWANEFTPILSMHDKNESPKRGSLLVAKYGKGHYVYTGLSFFREFPAGVSGAYRLFANMLSLGKNEMSENEQMKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDU7</accession>
    <name>A0A5C6ZDU7_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Adenosine 5'-phosphosulfate reductase</fullName>
            <shortName evidence="3">APS reductase</shortName>
            <ecNumber evidence="3">1.8.4.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">5'-adenylylsulfate reductase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Thioredoxin-dependent 5'-adenylylsulfate reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cysH</name>
        <name evidence="5" type="ORF">ESY86_17700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the formation of sulfite from adenosine 5'-phosphosulfate (APS) using thioredoxin as an electron donor.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>[thioredoxin]-disulfide + AMP + 2 H(+) + sulfite = [thioredoxin]-dithiol + adenosine 5'-phosphosulfate</text>
            <dbReference type="Rhea" id="RHEA:21976"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17359"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:58243"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="1.8.4.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="3">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the PAPS reductase family. CysH subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.10" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000027">
        <property type="protein sequence ID" value="TXD87269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00409"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004604">
        <property type="term" value="F:phosphoadenylyl-sulfate reductase (thioredoxin) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019379">
        <property type="term" value="P:sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01713">
        <property type="entry name" value="PAPS_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00063">
        <property type="entry name" value="CysH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004511">
        <property type="entry name" value="PAPS/APS_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002500">
        <property type="entry name" value="PAPS_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01507">
        <property type="entry name" value="PAPS_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000857">
        <property type="entry name" value="PAPS_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAPS_reduct" evidence="4">
        <location>
            <begin position="47"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; cysteine thiosulfonate intermediate" evidence="3">
        <location>
            <position position="229"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD87269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="233" mass="26923" checksum="7815B15BF3BD4FC6" modified="2019-11-13" version="1">MFETPLAHKVIPDLSEAEIKALNKKYKALTATERIAALYSDFDVSEVMLTSSFAATSAFLLKLFSEVNQEQTVFFIDTGYHFEETLRYKKELTKRYGLNVKSIGAIKEEHEFTTKDETWKKNPDFCCSINKVRPLDIIKNQYKVWVSGLMEWQSDHRSTLDIFEMRGEILKFYPLLDITKEARDAYIKEYDLPFHPLVAKGYNSIGCSHCTVPGEDRSGRWNNNPKTECGLHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDV9</accession>
    <name>A0A5C6ZDV9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GTP cyclohydrolase 1</fullName>
            <ecNumber evidence="5">3.5.4.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">GTP cyclohydrolase I</fullName>
            <shortName evidence="5">GTP-CH-I</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">folE</name>
        <name evidence="7" type="ORF">ESY86_17335</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>GTP + H2O = 7,8-dihydroneopterin 3'-triphosphate + formate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17473"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58462"/>
            <dbReference type="EC" id="3.5.4.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homopolymer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the GTP cyclohydrolase I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.16" evidence="5"/>
    <dbReference type="EMBL" id="VORO01000026">
        <property type="protein sequence ID" value="TXD87324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00848">
        <property type="reaction ID" value="UER00151"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003934">
        <property type="term" value="F:GTP cyclohydrolase I activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035998">
        <property type="term" value="P:7,8-dihydroneopterin 3'-triphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.286.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00223">
        <property type="entry name" value="FolE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043134">
        <property type="entry name" value="GTP-CH-I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001474">
        <property type="entry name" value="GTP_CycHdrlase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018234">
        <property type="entry name" value="GTP_CycHdrlase_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020602">
        <property type="entry name" value="GTP_CycHdrlase_I_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11109">
        <property type="entry name" value="PTHR11109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01227">
        <property type="entry name" value="GTP_cyclohydroI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00063">
        <property type="entry name" value="folE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00859">
        <property type="entry name" value="GTP_CYCLOHYDROL_1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00860">
        <property type="entry name" value="GTP_CYCLOHYDROL_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 5" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="GTP_cyclohydroI" evidence="6">
        <location>
            <begin position="54"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD87324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="229" mass="25881" checksum="6F33D0C6D0DC3EC9" modified="2019-11-13" version="1">MNTNTLKNNSQQLNGFSVEDIGEDHLSTGLETPMKADAFKFTDDEKKERIAILFEEIMDVMGLDLTDDSLKGTPKRVAKMYIDEIFSGLNPENKPKVALFDNKYRYNQMLVEKNITFYSNCEHHFVPIIGKAHVAYVSSGKVIGLSKLNRIVQYYAKRPQVQERLTNQIANELKSILDTDDVAVIIDAKHLCVASRGVKDDTSSTVTAYYGGKFNKTAKITELQNYINQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDW1</accession>
    <name>A0A5C6ZDW1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_15790</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1041" mass="115881" checksum="9C3F820853C062F8" modified="2019-11-13" version="1">MVKTIGSNGFEVGFTAFDINFNRNAIVASNILGRLKIPKLKDASGNDALIDINGHLNEEGYFNLTASEVQGIPLSLFDFVTINILSLELGKEDDKFYIGTSCEIWFENPIMNKILNGQKIVIPRLRIYDNGSMEIVGGNSFIPTNISLNLGPIEIAVTGIHFGSYQQEHDGKMRKYNYWGFDGAISLDPLGIDARGEGVKYYYTVDNDEKDENDNPKYSGGDSFLRIQTIEIDLVIPGTAGPDAAVAIIHGMVSIPEPGESQEYIGEVSLKLPKAKIAGSAAMRLQPRYPAFVVDASVDLPAPIPIGPLGIYGFRGLLGFRYVAEKEAVGLVSGEDTWYDYYKYPPKGVDISKFSGPERTSDYDFPFSVGAGAVIGTSFDSGTIISVRAMLLLSLPTLFLVEGRASILSARLGLDDNREPPFFAFVAWGDNSIEMGLGADYRLPLNNGEIIDLYAEVQSGFFFNNPRAWYVNFGTRDNPITARVLTIITAQSYLMLSATGIEAGARVEFDLRKRFGPARVRIYAYLEMGGFVSFERPQIGGYIALGGMIDINIWIVGITIGLDALFSVEAAKPFLIYAEIRIRVCVRIVFKVCKSFTVKLKWEKSGELDTQPIAPLPYKVAEYTLNRTKELVQGVHMLTNESFELTHKIDWVKLNQVTPWEPNHSEIDAIIPLDTYIDIKAAKGLIPGAVFSKIGGHTGGADNFTDLIPPQRVVRGGREIRQVKHKYSIEDIEIKAWTGSNWMDYHPFEAVVKAEDRNLVSNLRIGYWQRTGNQYDAIRLLATTPFSYTEAGEPGWLVPEQYGITPSELFCKSVRKDYDCANVLNKALGTTYYPPTQYTGHYINGAYFTLEGNFETLVTVNPDGTQNATISEDNFKITDTQNNFDFAKSIEFDNGNSLVIILQEPTLEVKLKLSTLAEGVTIRYYKSLGVENFNPIYEQIHEDYKSSAQLQQEVEYAHETEFIAKVVIEPRANSNSSESDCDICRLQDLLEQKLEECLEDRTNFGLNCLEEFADIIVSCGGVYADECDTVQYYDNMIIGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE00</accession>
    <name>A0A5C6ZE00_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thioredoxin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17355</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000026">
        <property type="protein sequence ID" value="TXD87328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="9"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="184" mass="20572" checksum="E2E2CAA398C68A3D" modified="2019-11-13" version="1">MARTTSKMMALGTKAPEFELLNTVDDSIESLHEWKGVKGTVIMFICNHCPFVKHVNHELSKLAKDFKPKGIECIAISSNDAKNYPQDGPQNMKQNAIDHDFIFPYLYDQTQAVAKAYDAACTPDFYAFDKDLKLVYRGQLDDSRPGNDIPVTGKDLRAALNALLDNSEISEDQKPSLGCGIKWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE17</accession>
    <name>A0A5C6ZE17_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Helix-turn-helix domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_17460</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000026">
        <property type="protein sequence ID" value="TXD87348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="HTH araC/xylS-type" evidence="2">
        <location>
            <begin position="13"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="660" mass="76142" checksum="44FB4119F807DA12" modified="2019-11-13" version="1">MTNQLSIDQVFINNLNTIIEDHIEDDQFGVEELAIALGISRSQLHRKLNAINGKSTSQFIREFRLEKAMEMLQDDVATASEISYKVGFNSPTYFNTSFHQYYGYPPGEVKFRNHLVNEDEEEIQASNAEKQPISIKRKLFNRTSFFIVALAILVIISFSYYNYSTSANTGPSENKESIKQEENTIAVLPLKNWSGDPELEYISDGMTDAIIAKLSQIQAIKRVMPFTSIVKYKDTDKDINTIAKELGVKYVLEGNFKLSGTQVQSNLNLVEAGNNKHLWSLEYTGVWNSDEIFELQASIAENIANKMKVNIGTTEIKSIKNKPTANEEAYKLYLRGQYEYSKLSKKGFDNAIYFFEQAISIDSSFIDPYAGLAKTHLIMGLVWGGESQIVAEKEGRKYYYKTVQLYQKGDLINQSELLRIKMMIEFHYDWDVESSIEDLNFVAESPNLYWEVYGMAMDIARKTGRFQLALTLTKRNLTFNPSNPGSYASLAQCYYMQGKNEMALQILKENDTVSADDYFYLLEASRVYYYLSEYKSSRQLLNIFMKIFTDRPPVIIWLNAVLNNVDGNKESQNYLDQLHQQYNTKVSGSPAWFLALYYAHIKDYDNTFVWLQKSYDRHEVEMTWLKEEPLLRPLRTDPRYIELYDKVGFAKIAPITPYVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE49</accession>
    <name>A0A5C6ZE49_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type II toxin-antitoxin system RelE/ParE family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_16770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000024">
        <property type="protein sequence ID" value="TXD87432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007712">
        <property type="entry name" value="RelE/ParE_toxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05016">
        <property type="entry name" value="ParE_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143011">
        <property type="entry name" value="SSF143011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="105" mass="12242" checksum="DCFB8EE1119903C9" modified="2019-11-13" version="1">MAFKIIWSEFAEIQLDEIYEYYEKKASSKIAAKLVKGIISAPGKLITSPYIGQAEDLLKERKIQYRYLVFKNYKLIYAVDKENGFIKIADVFDTRQNPPKMKPTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE60</accession>
    <name>A0A5C6ZE60_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PIN domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_14100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13470">
        <property type="entry name" value="PIN_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PINc" evidence="1">
        <location>
            <begin position="4"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="140" mass="16052" checksum="1D581C384F1CB8A8" modified="2019-11-13" version="1">MKNRLFIDTNIMLDFLGERHPFYEPIAKLATLADKGKVKMLVSPISFATVNYFLAKSESSKIAKEKLRKFKIISEICKLDEQTIEKGLNSPFKDFEDSLQYFSAVDSNCDIIITRNGKDFKKSLIPVMTAEEYLNSIRTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE79</accession>
    <name>A0A5C6ZE79_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cold shock domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_18330</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000031">
        <property type="protein sequence ID" value="TXD87017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04458">
        <property type="entry name" value="CSP_CDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012156">
        <property type="entry name" value="Cold_shock_CspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011129">
        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019844">
        <property type="entry name" value="CSD_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002059">
        <property type="entry name" value="CSP_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00313">
        <property type="entry name" value="CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002599">
        <property type="entry name" value="Cold_shock_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00050">
        <property type="entry name" value="COLDSHOCK"/>
    </dbReference>
    <dbReference type="SMART" id="SM00357">
        <property type="entry name" value="CSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00352">
        <property type="entry name" value="CSD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51857">
        <property type="entry name" value="CSD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CSD" evidence="3">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD87017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="63" mass="6938" checksum="5DBF8B51633DA4BD" modified="2019-11-13" version="1">MTGTVKFFNDSKGFGFITNEETGKDIFVHVSNLNGVELREGDQVEYTEEDGRKGLVAGNVQVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEE3</accession>
    <name>A0A5C6ZEE3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_18155</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000030">
        <property type="protein sequence ID" value="TXD87087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009218">
        <property type="entry name" value="HD_phosphohydro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21174">
        <property type="entry name" value="PTHR21174"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF035170">
        <property type="entry name" value="HD_phosphohydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="159" mass="18926" checksum="0601D4F37877DCAD" modified="2019-11-13" version="1">MLLQAEAIKEYISDYDALRFAIWYHDIICKATKGNNETKSAEFAINQLKATNFSKNRMEIVQNLIKSTQKHKVICPDNTDNAFLLDMDLSILGNDWSSYQSYIQNIRKEYAIYPDLIYKSGRKKVLQQFLKQERIYITKHYFERFEKQARLNIERELLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEJ6</accession>
    <name>A0A5C6ZEJ6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">3-oxoacyl-ACP synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12765</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="52"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="152" mass="16633" checksum="D0453F0D01D62FE1" modified="2019-11-13" version="1">MTNSTLKQELFKQCSAYVAQKFATIQNQIRDVQDGLTSETKSSAGDKHETGRAMLQLEREKLGHQLADIENTKANLQKIEPSAVSKSVILGSVVFTTEANYYIAVSAGTLTIDGQSFYAISPNTPIGLLLMGKVIGDQVYFREAGFEILKVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEL4</accession>
    <name>A0A5C6ZEL4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type II toxin-antitoxin system RelE/ParE family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_14175</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009241">
        <property type="entry name" value="HigB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05973">
        <property type="entry name" value="Gp49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143011">
        <property type="entry name" value="SSF143011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="110" mass="13119" checksum="D7519A2A91E0A4DE" modified="2019-11-13" version="1">MKPKFEVVFLEQAIDFMSKLDAKAKNKIYYNLDKAKLENDPKLFKKLTDDIWEFRTLYKGIQYRLFAFWDKTDKTETLVLSTHGMVKKVSKVPKSEIEKALKIRAEYFDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEL7</accession>
    <name>A0A5C6ZEL7_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PepSY_like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_16480</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021533">
        <property type="entry name" value="PepSY-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11396">
        <property type="entry name" value="PepSY_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022952286" description="PepSY_like domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="PepSY_like" evidence="2">
        <location>
            <begin position="54"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="147" mass="16757" checksum="04D68279D35CC598" modified="2019-11-13" version="1">MMRSLKLATLAIFATAAMSAQDLKMDEVPSNLADTFKKEYPQATDVEWEMDMANYKVEFDVNRMEHELWYSKEGKVMKSEMELTETDLPAAIASVLKSKYADYKVDSVEVTEENGAKTYEVDLEKGWNEELDLVFSANGEVLSEMKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEM1</accession>
    <name>A0A5C6ZEM1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000028">
        <property type="protein sequence ID" value="TXD87182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="203"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="245"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="279" mass="31737" checksum="13E1BD47B323DFF4" modified="2019-11-13" version="1">MAIHFLGIGLEYIDTVFQTIQNSDFSQYTIVGMKTLAVLFFLVNILKKYNEGIADKDGYTWGLSPSELAKNLAIVLLVIFSTQVLGFFDSILVAIESQYRTTAPALLPLQMQDINLEEEVGLLDAASMAMTLLYEALITPLYGFKIIAFVISTILWILDLFIYPLFLAERFFLLGIMQAFFPLVISLAVFEKFREMAYNFFKLYAAVYMLVPAFFLVNVFVNAIYIEINTNFWSNLFGTEFGQGFFAPVVQVGSVGFIVFLKFKLYRRATSFTLRLFTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZES5</accession>
    <name>A0A5C6ZES5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome oxidase subunit III</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_14500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the cytochrome c oxidase subunit 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019646">
        <property type="term" value="P:aerobic electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.80">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024791">
        <property type="entry name" value="Cyt_c/ubiquinol_Oxase_su3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000298">
        <property type="entry name" value="Cyt_c_oxidase-like_su3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035973">
        <property type="entry name" value="Cyt_c_oxidase_su3-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013833">
        <property type="entry name" value="Cyt_c_oxidase_su3_a-hlx"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11403">
        <property type="entry name" value="PTHR11403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00510">
        <property type="entry name" value="COX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81452">
        <property type="entry name" value="SSF81452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50253">
        <property type="entry name" value="COX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="111"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="268"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="311"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="COX3" evidence="7">
        <location>
            <begin position="1"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD88092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="332" mass="37588" checksum="27534AFE52C1586F" modified="2019-11-13" version="1">MDSTVVNTGAEGQTWDGGNDPLKSSYGKMMMWFFIVSDALTFSGFLAAYGFSRYKFSGSWPIADEVFTHVPFFHGNYPMIYVAFMTFILIMSSVTMVLAVDAGHHMNKTKVTWYMFLTIIGGMIFVGSQAWEWKTFIKGDYGAVQTQGGNLLQFGQYVTKDGEQTFKRVSVHDFAIVGNSERVQQQSNDGVWFLSEGTIPSLSMDEVINGIKANENILVRTEILDENGAKTILSRDESLKQLQANGRTVVEGANLHVNEYGSPLFADFFFFITGFHGFHVFSGVVINIIIFFNVILGTYERRGNYEMVEKVGLYWHFVDLVWVFVFTFFYLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF49</accession>
    <name>A0A5C6ZF49_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein BatD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_13165</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025738">
        <property type="entry name" value="BatD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40940">
        <property type="entry name" value="PTHR40940"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13584">
        <property type="entry name" value="BatD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023021110" evidence="1">
        <location>
            <begin position="22"/>
            <end position="591"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="591" mass="66490" checksum="FBCD72AFEFE43904" modified="2019-11-13" version="1">MNSLKHIPLILVMLITSMAFAQTKFETKVSKTKLGQNERLRVDFEMNKDGDNFNPPDFADFTVVGGPNTSVSNSWMNGIRSYAKTYSYFLAPTRQGTLKIGKATIEIEGETFSTDAVSVLVTAPVQRPNDPNNSVAKAEENLHLVAEVSKMNPYLNEAITVVYKLYVSQNIGVTDWRETSSPKYNDFWSQKIEMQNLQAQNGTFKGEAYRYVVLRKTVLYPQKTGKLEIEPLTLDLTVQVPTNRRDFFGGRHMAEVVRTISAGSRTINVKPLPEEGKPADFTGAVGDFKFNVITSKSKLNASESLEAKVEVTGNGNLKLFQLPKLKLPSSLEVYEPEHNENVRTDLGGMQGSISDNYTVVPQYKGKYPIPSISFSYFDLNTETYKRVSSGEIVIDVIEGPINSTAGDNNRIASEGNKQKVVLSNDQFAYIKTDAKLKPINQPDFFNSSVFWSSMLLPLLAIPLALVYRKKKEERDADVFGNKIRKADRLAKRYLSEAKKSLGQKEAFYIALERALHNYLKGKIHIETSDFSKEKIEEILLKEQVDQATVAEFISILQHCELARYTPITNVEMQQDYEKAARTISVIDKDIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF78</accession>
    <name>A0A5C6ZF78_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11845</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="173" mass="20764" checksum="7386BBE7C9F2F128" modified="2019-11-13" version="1">MYYIIGFLATVMLIRFITNFYKYKRIQKLFKKYQEYLQTNALEFAQYKQEIISLLKDAGLKDFSIIHQESLGYGNFANMQVSGFDNLTNRRVDIVGSIRMRFNEAIGVFRKRFKESFNPIFWIDFIVKFPQYLMEFFGVLPEKVAVRIFLVIYWLLAILFGLKKFEILDYLMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF83</accession>
    <name>A0A5C6ZF83_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11895</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="1">
        <location>
            <begin position="45"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="419" mass="46554" checksum="FB274BC19D4A11EC" modified="2019-11-13" version="1">MKDLFEKIYRDKGPLGKWASQAEGYFVFPKLEGKISNRMKFQGKEVITWSINDYLGLANHPEVRKIDAEAAAEYGSAYPMGARMMSGHTDLHEKLQNELAEFVSKEAAYLLNFGYQGMVSTIDALVSKDDIIVYDVDAHACIIDGVRLHMGKRFTYKHNDVESLEKNLDRATKMAEQTGGGILVISEGVFGMRGEQGRLREIVALKKKYNFRLFVDDAHGFGTLGATGAGAGEEQGVQDDIDVYFATFAKSLASTGAFIAADQEIIDYLKYNLRSQMFAKSLQMQLVVGALKRLDMLRTMPELKDKLWENTDALQSGLKARGFDIGTTQSCVTPVYLKGSIPEAMALVRDLRENYGVFCSIVVYPVIPKGLILLRMIPTATHTLEDVTVTLDAFEAIRTRLENGTYRRLSAAVMAAMGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFH0</accession>
    <name>A0A5C6ZFH0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_16655</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000023">
        <property type="protein sequence ID" value="TXD87524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="84" mass="9778" checksum="0D97263C9582ED5B" modified="2019-11-13" version="1">MDYLLKASAVLIIFYVCYYLFLRRETFFQTNRWFLLAGLVVSICIPFLVIPMYIEYVPLDLTGFANTTSTRGTTPITQEPFDYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFT2</accession>
    <name>A0A5C6ZFT2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">LysR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_10775</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="299" mass="33732" checksum="8696206F13A4FED3" modified="2019-11-13" version="1">MFDYKLQVFLSVAMRLSFSKAAEDLHITQPAITRHIKLLEEHFNQKLFERKGNSIALTKAGDLLVVHSKRLKSLHEALQFDMNALIDKTAGELRISASTTIAQYVLPMVLADFRKKYPKIKISLNSDNTEKVEQNLLQQNAEIGFIEGQSKNRELAYHEFLRDEIVLVVAKGHSLYNAKAITSKNLQSLPMILREKGSGTLEFISNALKAIGIPMTALQVEIHLGSSESIKSYLKDRQSVAFLSVNSVLDELASGDLGIVDVENFSIERPFNIIFKHGHQSSLSQLFLQFIQHHYNINL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFU9</accession>
    <name>A0A5C6ZFU9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2975 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_13680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021354">
        <property type="entry name" value="DUF2975"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11188">
        <property type="entry name" value="DUF2975"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="158" mass="17694" checksum="B1498439FB7B307C" modified="2019-11-13" version="1">MKKLKFLNGFVIGLMALFVLIILVNLYIGEISNFGKTLKGSYDQVVFGQWTPYLYLLFYVPILVALLYIQRGLMTILKDNLFNIKSAKRFKIASTLLFITGVFGLIFDSILFLNLKGVVGFGYLGQDVLILFIGIILNIVADIIVNGSSLKTENELTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFY6</accession>
    <name>A0A5C6ZFY6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TolC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_14575</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="249"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="480" mass="53584" checksum="1F432CF04B7E2CAD" modified="2019-11-13" version="1">MKKIVSLIIVLITLGVNAQNKKWTLTECVEHALENNISVKQSELNLEATDIDRLLALGNFMPSLNLSSSVSENTGLSFNPVTNNAQTTTFLSFTGRGNIGYTLFDGLRNIREVQRAKIAKLASQYRLLKMKDDISLLVANSFLQVILNKANLEVLQSQNEVTIEQMERTQQLVDAGSLPQGDLLEIRAINASELQNIVNAENQIQISLISLAQLLLIKDYETFDVQDAGYNIVDGGIADKSVSEIMSGARDNRSEIKIAEQDVELAKKDVQLAKGNYLPTLSAFFGYDTRFTNAQSFIQDLDPDEPLVTQQIGVVEATGQPVVGQFPNTITRQAGAEPFFNQLYQNDGIGYGLSLNIPIFNGFSTRSNVKRSEINLRRSNFQLEQAELDLESNVYQAYVDAKGSLKSYEAAKSAVESQELAYDYAKERYDVGLTNAFDFSQSKLRYDNSKIDMNNAKYDYIFKLKVLELYFGVPANELKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGD6</accession>
    <name>A0A5C6ZGD6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carboxypeptidase-like regulatory domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023017887" evidence="1">
        <location>
            <begin position="20"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="260" mass="29687" checksum="F18A42AD1AD352C6" modified="2019-11-13" version="1">MKQPIALFFTLFMSMVSFGQEEDTSVKGTVIDLSTDLPIDRVNIVNLNQVIGTATNDQGEFEIKAQLNDTLHLSYIGYKSIKVRVTNDWLKFGETKIGMTELALALEEVVVNQLKLTGYLEVDVKQVPIKSNYRYSISGLPNSGYEAGDRRPNAVSKVIGAIFNPADFLHNVFGKKPNELRKLRKMKEDDEIRNLLASRFDREMLLVLLQVDRFDLDEIVNQCNYSKDFIRSANDLQILDAISECYEEYKILNRNKSGRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGM5</accession>
    <name>A0A5C6ZGM5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF2807 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_12695</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021255">
        <property type="entry name" value="DUF2807"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10988">
        <property type="entry name" value="DUF2807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022819114" evidence="1">
        <location>
            <begin position="19"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2807" evidence="2">
        <location>
            <begin position="28"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="224" mass="24789" checksum="34A742557AA42957" modified="2019-11-13" version="1">MKSIANLLVFLFALNAFAQNPIQKEVDDFTEIKVFDLIAVNLIKADENRVEITGDDIQDVEVINKNGKLKIRMKLDKSFNGERTFVSVYYTNLEIIDANEGAYITANELIEQDQIALKAQEGARLKIGLDVDKVNIRAVTGGIVETRGRANSQDIVLNTGGIYEGKDFETKTTKVDIKAAGEANVNASENVDARVIAGGDVYIYGNPQNIKEKTTFGGRIQRMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGP8</accession>
    <name>A0A5C6ZGP8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Hydroxymyristoyl-ACP dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_13090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013114">
        <property type="entry name" value="FabA_FabZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30272">
        <property type="entry name" value="PTHR30272"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07977">
        <property type="entry name" value="FabA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="148" mass="16451" checksum="1E3A9D4C61E7BB06" modified="2019-11-13" version="1">MNSHAILNLLPYQDPFLFVDGLTSITSEGVEGYYTFESDSYFYEGHFKDNPVTPGVILTECMAQIGLVCLGIFLLKESLSGSNSPQIALTSSQMDFFLPVLPGEKVRVVSEKEVFRFQKLKCLVKMYNEKNELVCRGKLSGMMSAGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGR4</accession>
    <name>A0A5C6ZGR4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GNAT family N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10095</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="155" mass="18382" checksum="8F619DE34C625A07" modified="2019-11-13" version="1">MDIDYREATLEDLPEITAIFRDTISTVNRKHYSEEQVEAWAAAADNLKKWQKRIKATYFLVAENDGQILGFAWLKNGNYLEGMYVHKNYQRKTVGSKLLRIIESHVTMYDFESIQAESSLSSLPFFDSHYYEVEKKQKRSIKDQVLDYYIMYRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGZ5</accession>
    <name>A0A5C6ZGZ5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">His_kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_13075</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011110">
        <property type="entry name" value="Reg_prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010559">
        <property type="entry name" value="Sig_transdc_His_kin_internal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06580">
        <property type="entry name" value="His_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07494">
        <property type="entry name" value="Reg_prop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="781"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="domain" description="His_kinase" evidence="2">
        <location>
            <begin position="826"/>
            <end position="900"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1029" mass="116673" checksum="790CC5C16144C056" modified="2019-11-13" version="1">MNYFKSAPKIVSCMLIALSNLKQLLAYPIFIFFFGISVALQGQNEQLRAFTLEDGLPQSQVFDMVQDAKGYLWLGTQGGGLARFDGSEFKVFNTSNGLNSNYIHALKAMNDTLYVGTKRGLSVLLKTNFVSSPMPQINSFKSFGNKVYALTARGLYEISANLKPIKIKLTAALDQAHLNDLVFDGKQYWLASKSGLFKLSNLSEKTRTIKKMESNNFVALVFYEDNIFAATFNDGTFIFNPNHFEDALLMREPLRINTMSIQNSNALWVTTDSDGISIIDTETFRTTSTISTTNGLSVPHVRMVLKDQQSNLWIATSGGGFYKYFQNNFKHYDTSTGLKGNRIYAVHSTNDGLWLSNSEQGLSKIDPLGVHTILPPENFSEVKIKTLASDHNGNIWSGSDGRGLWFRETKTRDTILRDNSIIDELKQVTIPLKTVTDYVLNTETGFPYDWIRSLQIEKDTIWAATYSSGIVKFSFDSKTENFKIYKVFASAEGIADLYIMQIVPHKDQIWYATQNGHLGFIKNGKVTHLGLVLDQDVAINSMLFQNNTLYLGTAGKGIWWAELGDQLNFKKLKGAKPLSSDNCFQLIFDDQGYLWAGAERGVDKIELNPEHEITEVYHFSRDDGFLGMETCLNAVDKDARGHLWFGAIYGLTEFQPNEQTSISQKPKVFFDDVKVAYQSVDSINLQDWTNSAKVLKLQPDQTQVSFSYKSIDLNHPNDIEYRSKLNETEWSPWSKENTQNFSGLAYGSYEFTVVSRNSRWEESTPKRFSFYIDSPWYQKTIVQWAGAALILNILGILIWSYIRRLKRKNKAAQERLKLENHLLGLEQKALRLQMNPHFMFNVLNGIKAMAKTKPDKMNATIQSFATLLRETLINSRKELISLEEEMSSLQHYIEVEQLMAQKPFAFEMHLDSDYEAEAIQIPPMLIQPFVENAIRHGISKVEALGQLKLNFKTTEDLLYVTISDNGIGIYEAQKQKQKTDHQSMALKVTEERLASISGKNALQITELKNNDGSIKGTQIVLKIPLETDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH38</accession>
    <name>A0A5C6ZH38_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="115" mass="12638" checksum="6D9E59CC66A97C33" modified="2019-11-13" version="1">MESIEKNTVTSESEGKNIAIIAYITVIGLIIAFVMNSDKKNSFASYHIKQSLGLALTGLALGIIGLIPILGWLINILGIFVLLFMWIMGLVNAINGQEKPVPILGTMYLEWFKNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH67</accession>
    <name>A0A5C6ZH67_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">T9SS type A sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_09715</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022715088" evidence="1">
        <location>
            <begin position="22"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="domain" description="Por_Secre_tail" evidence="2">
        <location>
            <begin position="498"/>
            <end position="563"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="565" mass="60187" checksum="D35346F8312E090D" modified="2019-11-13" version="1">MKNIYSVILLFLMGLNLYAQTSVDTGRTTLTAYTFDGTWSPGDPNGISTGDDDIFVTSGNASITADTSIGNVTVSPGAALTVDAGATLTASMVSLESNSDSYSSLISSAGSINGDIEYKRHVNGTVAAGVTTGGNDLISAPLTGQTFEDFQLANDNIVSNTGETLFLFGPLDSSTNVLGLYSNTETATLDPGVGYRAAADGTNGGTFTFNGDLNTGDVSANILNSGTNAVQWNLIGNPYPTYLSVQDFLNHEVATGVKNIDLMTSTSSGIYGYKGDLSTGYTIYNLINIDETTLIAPGQGFYVSADAADVAAHDIVFTPDMRRTGTGDDFIEGRSTTVENKYLQLRISNSSKTFDTEFYFSENASLGLDPGYDAALFGDAAPAFSIYSELVEENTGRFMAIQCMGMTDMNDVSVPLGVNAAMGQQISFSINQSTLPAYIDVYLDDTLNNTYTKLNTGNYTLTSSTAINGTGRFFLRFANSTLGTAVATAHTVEVYSVKDKVIIKGRLDQNSTFMLYDIQGRLIMETKLNQNATNQYIDVSSMPKGTYIVKLSSATLLKTQKLILN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHB9</accession>
    <name>A0A5C6ZHB9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">TPM domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_12335</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007621">
        <property type="entry name" value="TPM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04536">
        <property type="entry name" value="TPM_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022672476" evidence="5">
        <location>
            <begin position="37"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="192"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="TPM_phosphatase" evidence="6">
        <location>
            <begin position="50"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD88580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="287" mass="30261" checksum="E269E27B6E6E3AD1" modified="2019-11-13" version="1">MIFWDRANVARENSRTTWRGFLLAMALMLCSSMSFAQFDIPPVPKEQTSVYDYVDLLSASEKSNLEQKLIRYSDTTSTQILVAIIASTKGENIGLLAPKWAQKWGIGQAKEDNGVFILLAREDRKIWISPGYGVEDRLTAGITGELTRNVIIPQFKRGDYYEGLNQGADAIFDVLTGKYQATRKQSNNSQGLPMGTFLFIFVVFVVLMVIFSKKRGGGGGSGGKRSGGVSLLDAIILSNLGRGSFGGRSSGGGIFGGGSSGGGFGGGGFGGGFGGGGFSGGGAGGSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHR3</accession>
    <name>A0A5C6ZHR3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Type IV secretory system conjugative DNA transfer family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_09670</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VirD4/TraG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003688">
        <property type="entry name" value="TraG/VirD4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02534">
        <property type="entry name" value="T4SS-DNA_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="27"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="524" mass="59846" checksum="C377116B951F9E9B" modified="2019-11-13" version="1">MDNFLNIFFVVGFTSTLFYGTFRVSRYAFIFNILILGLLLFYLSNESEVIPILLYLVCPLMLINIGLYVFLHKTEKPKTANAKYQVNFATTKGNFKLDNIKRGASVIGSAGSGKTESVVYGFLKHFQEQDFCGIIHDYKDFELTEMAYPLFKGGDIPFKVISFDKIIHRVNPIAPRYLENEESVNEVSRVLIENLLEQRESGSTGTTKFFNDAAEGLIGGLIWKLKTSYPQFCTLPHLIAIYQYLDTDSLIQFLESNITSRAMADAFISGKDSERQTAGVKSTLANALKRISTQRIFMALSADEVPLNINSPENPTVISVVNNPKFETSYSPVIATIIHTITKQMSVRKAKPSFLMMEEAPTIRLLNMHRIPATLRSYNISTIYVMQDKIQNDMMYGDKASKAILSNLSYQFFGKVNDPDTAKYYERFFEIVKDPTKSVSRGHNLDFDTRITTGEKEIPKIRADVFFRLKQGEFITYADGKDKRVQFKLQKIERELPKNYKEFSSAELEANFERIYHEAKSIFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHZ1</accession>
    <name>A0A5C6ZHZ1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CatB-related O-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_09800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="228" mass="25603" checksum="FABB3FC27C798C6B" modified="2019-11-13" version="1">MNSIKNKVAHRIFSLLLTKNYTSTNSCVTYPKNATVYGNHFNGKIAIGKNSKILRTECYGQIDIGDHTALNGPNLSIYAGDGKVAIGNFCSIARNVSIQLDGHNYNKITSYQIFKNFFHTENTSEIINNGDMTIGNDVWIGANAMIYGNVSIGDGAVIGSNSFVNKDVPDYAIVVGSPAKIIKYRFEDDLIKELKQLKWWHWDEQTLRKNQFLFENELTLEALKKIQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI39</accession>
    <name>A0A5C6ZI39_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Aconitate hydratase A</fullName>
            <ecNumber evidence="4">4.2.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Iron-responsive protein-like</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">RNA-binding protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">ESY86_06540</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>citrate = D-threo-isocitrate</text>
            <dbReference type="Rhea" id="RHEA:10336"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="EC" id="4.2.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate from oxaloacetate: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.3" evidence="4"/>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00718"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003994">
        <property type="term" value="F:aconitate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047780">
        <property type="term" value="F:citrate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018136">
        <property type="entry name" value="Aconitase_4Fe-4S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015932">
        <property type="entry name" value="Aconitase_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006248">
        <property type="entry name" value="Aconitase_mito-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00415">
        <property type="entry name" value="ACONITASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="SSF53732"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01340">
        <property type="entry name" value="aconitase_mito"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00450">
        <property type="entry name" value="ACONITASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="16" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Aconitase" evidence="14">
        <location>
            <begin position="34"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="domain" description="Aconitase_C" evidence="15">
        <location>
            <begin position="557"/>
            <end position="684"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00019378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00031081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00031977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="TXD89855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="754" mass="82316" checksum="F21197BDB26FBC93" modified="2019-11-13" version="1">MAFDIDMIKDVYSKMPERVDAARNIVGKPLTLSEKILYAHLWDGKTDKAFTRGKDYVDFAPDRIACQDATAQMALLQFMQAGKPNVAVPTTVHCDHLIQAKQGAVPDLKRANENSHEVFDFLASVSKKYGIGFWKPGAGIIHQVVLENYAFPGGMMIGTDSHTVNAGGLGMVAIGVGGADAVDVMAGMAWELKFPKLIGVKLTGNINGWTSSKDVILKVAGILTVKGGTDSIVEYFGPGAKNLSCTGKGTICNMGAEIGATTSTFGYDDSMERYLRATDRAEIADEANKIREYLTGDDEVYANPEAYFDQVIEINLDELRPHLNGPFTPDLATPVGELGKKARENGWPIKVDWGLIGSCTNSSYEDLTRASSIAQQAVDKKIKPKSDFGINPGSEQIRFTAERDGILKIFEDLQATIFTNACGPCIGQWDRSDRKGDEKNTIVHSFNRNFSKRADGNPNTHAFVGSPEMVAAIAISGRLDFDPMNDTLINEDGEEVKLEEPRGIELPPKGFAVEESGYVAPVADGSEVDISVSKDSERLQLLAPFEPIGNQIKDAKLLIKAFGKCTTDHISMAGPWLRFRGHLDNISNNMLIGAINAFGKKTNFVKNQLTGEYGGVPDVARAYKAEGVKSIVVGDHNYGEGSSREHAAMEPRHLGVVAVIVKSFARIHETNLKKQGMLGLTFANENDYDLIQEDDTFNFLDLDQFAPDKQLAIEIVHSDGSKDTFKVNHTYNQAQIDWFNEGSALNLIKKENAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI94</accession>
    <name>A0A5C6ZI94_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10365</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD89006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="158" mass="18789" checksum="1B118366FCC7B3E4" modified="2019-11-13" version="1">MVIGSLIGVLIALTPFLFYSYIYIPEESHWDAFLFTYHSGFYNNARTGMWSILGKFVPLFLLFIWFFTCRHWWFHAILVPISMFTYQIIGVINDDIIFFDNFDLIYMVPIMAVIIPSIYLIRAKMFDKINNADKSMKEIEEEFMIKPKGLMNTLKQYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIC2</accession>
    <name>A0A5C6ZIC2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ComEC family competence protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_09305</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004477">
        <property type="entry name" value="ComEC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025405">
        <property type="entry name" value="DUF4131"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03772">
        <property type="entry name" value="Competence"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13567">
        <property type="entry name" value="DUF4131"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00360">
        <property type="entry name" value="ComEC_N-term"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="32"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="255"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="289"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="332"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="360"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="391"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="423"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="451"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="483"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="510"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4131" evidence="8">
        <location>
            <begin position="33"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="Competence" evidence="7">
        <location>
            <begin position="235"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD89234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="678" mass="76711" checksum="491F38EC87A305EA" modified="2019-11-13" version="1">MKLLNFTIIKLTVCLVLGILLAEFLKISVATSLYLAASLMLGVGILYVLGRFQNRSKVWFGALVLLATISLGILSYNLHNQSNFEAHYGRFISEDPSAEHALQLKIRQRLKPSVYHDKYVATVLKVGRNDTKGKILVNIEKDTLSLRLKVDDVLLVSSGFTPLTSPLNPNQFDYKDFLRKQYIDHQLFTEAAHILPISSKRNTIYGYAAAIRLHINQSLKTYDFSPEVLAIINALILGQRQDMSKAIYDSYTNAGAIHILAVSGLHVGLILLLLSIALKPLEHLKHGRLIKAIFIVMLLWSFAVIAGLSASVTRAVTMFSIVAIAMHWKRPTNIYNTLAISMFLLLLFKPTFLFDVGFQLSYTAVFAIVSIQPLVYRLWRPKWKVLDYPWQIFTVTLAAQLGVAPLSMYYFHQFPSLFFISNLAIIPFLGFILGFGILVIILASLKFLPQFLAEFYGGVIDLMNFIVAWVSKQEAFLFKNVPFDGLQVVACYALLICLVIWYRAPKFKTLSFALVAIVVLQMSWLYTKYHHSENSLIVFHKSRHTLLGIKTGSQFSIAQEFDSTTLAKDHIIENFKVGNFIKSSTRDSVKNVYAFRSRHLLVVDSTGIYGVQRFKPDYVLLRNSPRINLNRLIDSIQPKMIIADGSNYKSYVARWKATCTQQKLPIHITSEQGAFVLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIM6</accession>
    <name>A0A5C6ZIM6_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_04700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pseudouridine synthase RsuA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120159">
        <property type="term" value="F:rRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042092">
        <property type="entry name" value="PsdUridine_s_RsuA/RluB/E/F_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000748">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB/E/F"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018496">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00093">
        <property type="entry name" value="TIGR00093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01149">
        <property type="entry name" value="PSI_RSU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S4" evidence="4">
        <location>
            <begin position="6"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="250" mass="28737" checksum="2B080855AE17BFE4" modified="2019-11-13" version="1">MDENLTRINKFLSEAGYCSRRAADKLIEAGRVTINGEVPEMGTKIAPNDKVHVDGELIKNSKEDFVYLAFNKPIGIVCTTDTRVEKDNIIDYINYPKRIFPIGRLDKPSEGLILLTDDGDIVNKILRASNNHEKEYIVTVDKTISQTFVQRMAGGIYLEDLDKTTKKCEVRRLDSNRFSIILTQGLNRQIRRMCEYLNYEVLALKRTRIMNIPLDMPTGEYRELSKTEFETLEAMLEDSTKKHEAKKKLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIN6</accession>
    <name>A0A5C6ZIN6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_09055</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="78" mass="8979" checksum="E0BF96B0F26A0CB2" modified="2019-11-13" version="1">MNLLDFVIEKFGNQSAKQLVNYTHRENSPWHKTAIEHSVLGLLDNEAINNTELVIDKSSLIQHDARKKLVYNDFVEAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIP9</accession>
    <name>A0A5C6ZIP9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Multidrug export protein MepA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ESY86_07470</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family. MepA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13143">
        <property type="entry name" value="MATE_MepA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001104">
        <property type="entry name" value="3-oxo-5_a-steroid_4-DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045070">
        <property type="entry name" value="MATE_MepA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006603">
        <property type="entry name" value="DinF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50244">
        <property type="entry name" value="S5A_REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="22"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="95"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="137"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="167"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="193"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="286"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="318"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="363"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="388"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="416"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="S5A_REDUCTASE" evidence="9">
        <location>
            <begin position="410"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD89616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="453" mass="49512" checksum="807B0B5938635F46" modified="2019-11-13" version="1">MAGISSKDLGTLPIGKLLIKQAVPASIGILVMSLNILIDTIFVGNWIGSTAIAAINVVLPVSFFIAALGMSIGIGGSSIISRALGADNMPKALKVFGNQLTLTLLLTVTMVIFGLWYIDDIIPVFGGKGAIFDPAKVYYEIVLYGIPFLAVCMMGNTVIRAEGKPKFAMYAMMFPSVGNLILDYFFINVFDWGMAGAAWATTGSYILCFIFIVWFFLSKHSELKIDLAHLGLNWSIVKEISSLGSVTLARQAVVSITYLFMNNILYDLGGETSVTSYAIVGRMLMFALFPVYGITQGFLPIAGYNYGAQQYDRVKETIFTALKYAAGLATVVFILLMVFPEAITRLFTQNADVLRETPGEMRWVFAATPIIAIQLIGAAYFQAVGKAIPALLLTLTRQGFFFIPLILILPHYMGEIGVWISFPIADVLSTIVTGFFLFREMKLKLNQPVSEVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIQ6</accession>
    <name>A0A5C6ZIQ6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Thioredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">trxA</name>
        <name evidence="5" type="ORF">ESY86_04945</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005746">
        <property type="entry name" value="Thioredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000077">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01068">
        <property type="entry name" value="thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2 3" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="3">
        <location>
            <begin position="24"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000077-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="99" mass="11161" checksum="31BE33A3031C9C9E" modified="2019-11-13" version="1">MMSKFSELINQDQPVLVDFFADWCGPCKTLAPILKQVKEDLGDKVKIVKIDVDKNQALAAKYQVRGVPTMLLFKNGKQVWRQSGVLQKNDIINVIKTNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIU0</accession>
    <name>A0A5C6ZIU0_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Imidazole glycerol phosphate synthase subunit HisH</fullName>
            <ecNumber evidence="8">4.3.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">IGP synthase glutaminase subunit</fullName>
            <ecNumber evidence="8">3.5.1.2</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">IGP synthase subunit HisH</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">ImGP synthase subunit HisH</fullName>
            <shortName evidence="8">IGPS subunit HisH</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">hisH</name>
        <name evidence="11" type="ORF">ESY86_10460</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + L-glutamine = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + H(+) + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24793"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="ChEBI" id="CHEBI:58525"/>
            <dbReference type="EC" id="4.3.2.10"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 8">
            <text>H2O + L-glutamine = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="3.5.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 5/9.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterodimer of HisH and HisF.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.10" evidence="8"/>
    <dbReference type="EC" id="3.5.1.2" evidence="8"/>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000107">
        <property type="term" value="F:imidazoleglycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01748">
        <property type="entry name" value="GATase1_IGP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00278">
        <property type="entry name" value="HisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010139">
        <property type="entry name" value="Imidazole-glycPsynth_HisH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42701">
        <property type="entry name" value="PTHR42701"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000495">
        <property type="entry name" value="Amidotransf_hisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01855">
        <property type="entry name" value="IMP_synth_hisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="6 8" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GATase" evidence="10">
        <location>
            <begin position="5"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8 9">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <feature type="active site" evidence="8 9">
        <location>
            <position position="175"/>
        </location>
    </feature>
    <feature type="active site" evidence="8 9">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000495-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD88912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="194" mass="21596" checksum="B1EA350BA20CD772" modified="2019-11-13" version="1">MKIVIIDYGAGNTKSVQFAMKRLGVEAILSDDAEIIKNADKVIFPGVGEASSAMKMLASKELDKLIPTLKQPVLGICLGMQLMCTFSEEGQTKGLGIFDVQVKKFNNQLKVPQMGWNSIFSLKSDLLKDIKNDEFMYLVHSFYAEICEQTIATTNYGLDYSSALQNDNFYGVQFHPEKSSTAGEQILRNFLEIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIY3</accession>
    <name>A0A5C6ZIY3_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">UDP-3-O-acylglucosamine N-acyltransferase</fullName>
            <ecNumber evidence="5">2.3.1.191</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">lpxD</name>
        <name evidence="7" type="ORF">ESY86_11640</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a (3R)-hydroxyacyl-[ACP] + a UDP-3-O-[(3R)-3-hydroxyacyl]-alpha-D-glucosamine = a UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + H(+) + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:53836"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="ChEBI" id="CHEBI:137740"/>
            <dbReference type="ChEBI" id="CHEBI:137748"/>
            <dbReference type="EC" id="2.3.1.191"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Bacterial outer membrane biogenesis; LPS lipid A biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the transferase hexapeptide repeat family. LpxD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.191" evidence="5"/>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00973"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016410">
        <property type="term" value="F:N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03352">
        <property type="entry name" value="LbH_LpxD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00523">
        <property type="entry name" value="LpxD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007691">
        <property type="entry name" value="LpxD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020573">
        <property type="entry name" value="UDP_GlcNAc_AcTrfase_non-rep"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43378">
        <property type="entry name" value="PTHR43378"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04613">
        <property type="entry name" value="LpxD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01853">
        <property type="entry name" value="lipid_A_lpxD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2 5" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="1 5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="4 5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="LpxD" evidence="6">
        <location>
            <begin position="24"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD88618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="331" mass="35123" checksum="75A4C36E3AC4A224" modified="2019-11-13" version="1">MASYTISEINNILKAELIGNTTQKIEGPEEIRKASPTQITFIGSKKYAKFWPDSEACAALVHTDLDLEPGENRAFLKVKNVDLAMAKLLELFNPPTPVFDTDIHPTAVIHETAKIGAGCKIGANCYVGKAVELGSEVILYPNVCVFDDTTIGNNTIVWSGTIIRERCIIGSHCIFHTNVSIGADGFGYRPSEDGKGLVKIPQIGNVIIGHYVEIGANSCVDRAKFSSTIIGDGCKIDNLVQIAHNSIMGRSCIMAGHSGLAGSVTLGDGVVIGGSASIKDHTTIHSGATVGAGSGVIGDVEAGKTVLGYPAQDARDMLKQWAAIRQFLKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ38</accession>
    <name>A0A5C6ZJ38_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Sec-independent protein translocase protein TatA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">tatA</name>
        <name evidence="8" type="ORF">ESY86_05960</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Forms a complex with TatC.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the TatA/E family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033281">
        <property type="term" value="C:TAT protein transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043953">
        <property type="term" value="P:protein transport by the Tat complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00236">
        <property type="entry name" value="TatA_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003369">
        <property type="entry name" value="TatA/B/E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006312">
        <property type="entry name" value="TatA/E"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02416">
        <property type="entry name" value="TatA_B_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0811">Translocation</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD90278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="96" mass="10607" checksum="AC44A9091FE48BDB" modified="2019-11-13" version="1">MIQLATFLFIGTTEVIFILFILVMVFGADKIPEIAKGMGKGMRMLRDASTDIKSEITKTANKQGINTDVTKDIQGEITKVKDELEGFTGSVKRHSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ45</accession>
    <name>A0A5C6ZJ45_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Endonuclease III</fullName>
            <ecNumber evidence="1">4.2.99.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">DNA-(apurinic or apyrimidinic site) lyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">nth</name>
        <name evidence="3" type="ORF">ESY86_06115</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-monophospho-2'-deoxyribonucleoside-DNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66592"/>
            <dbReference type="Rhea" id="RHEA-COMP:13180"/>
            <dbReference type="Rhea" id="RHEA-COMP:16897"/>
            <dbReference type="Rhea" id="RHEA-COMP:17067"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:136412"/>
            <dbReference type="ChEBI" id="CHEBI:157695"/>
            <dbReference type="ChEBI" id="CHEBI:167181"/>
            <dbReference type="EC" id="4.2.99.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="1">Binds 1 [4Fe-4S] cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Nth/MutY family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.99.18" evidence="1"/>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140078">
        <property type="term" value="F:class I DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019104">
        <property type="term" value="F:DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00942">
        <property type="entry name" value="Nth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005759">
        <property type="entry name" value="Nth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="SSF48150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0227">DNA damage</keyword>
    <keyword evidence="1" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="1" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENDO3c" evidence="2">
        <location>
            <begin position="39"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="218" mass="24935" checksum="EBC219A9C1336E65" modified="2019-11-13" version="1">MTKPEKVEFVINTLKELYPTIPVPLDHKDPYTLLIAVLLSAQSTDVRVNQITPLLFQKADNPYDMIKLSAEEIRDIIRPVGLSPMKSKGIYGLSHILIDKHDGQVPQSYEDLEALPAVGHKTAAVVMSQAFGIPAFPVDTHIHRLMYRWNLTNGKNVVQTEKDAKRLFPEAIWNDLHLQIIWYGRQYSPARAWDLEKDIITKTVGRKSVLDTYYKSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ70</accession>
    <name>A0A5C6ZJ70_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_07425</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="88" mass="10350" checksum="0CAB5B7D05FF5FB7" modified="2019-11-13" version="1">MTKIYTKSEFQELEFDSKCVIIESLLTNAYFEGQEKIGFQVEIDENNNLLPVPSEIKEMESKKFEALILDLTEKLFAEKIEIEFDTEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ94</accession>
    <name>A0A5C6ZJ94_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GNAT family N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038740">
        <property type="entry name" value="BioF2-like_GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13480">
        <property type="entry name" value="Acetyltransf_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Acetyltransf_6" evidence="1">
        <location>
            <begin position="150"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="323" mass="37513" checksum="9671E53B77D5EC04" modified="2019-11-13" version="1">MFTVKIYLPEQHRVWNDFAAQAKNAPFLFQRGFMDYHKDRFEDFSLMVYRNGKLVALLPANRVEATLYSHQGLTYGGLLLKETTKFRDVIFMFKSVLEFLSAQAVETLALKLLPSMYSAQPNDELNYLLFLTEAQLTRRDALSVLNMNNRPKISRNRMEGVSRGQKYNLIIREVDSFDEFWNAILTKNLQQKHAATPVHSLEEISALKKSFPKQIRQFNVYQDNQIVAGTTIFETETLAHSQYISGNEDKNTLGSLDFLHWHLIEDVFKHKAFFDFGTSNEHQGKKINEGLQYWKEGFGARTITQDFYSVNTKNHKLLDTVML</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJD7</accession>
    <name>A0A5C6ZJD7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="125"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="261" mass="30344" checksum="FCFBA1F92DCCAB85" modified="2019-11-13" version="1">MSKQLFKYILNTIPRPILIRLSYVARPVLALALTGDTFTDPIDGKSFKTFLPYGYGNQRNNVLSPSTLSLERHRLLWLYLKRETNFFTSESSTEPKKEVLHFAPEQCFLKRFRQLKHIDYTTTDLLSPIADVKADICDLPFKDNSYDLIFCNHVLEHIPDDTKAMEELYRVMKPGGFGIFQIPQDLNREVTFEDDSITDEKERARIFGQYDHVRVYGRDYFDKLRKVGFKVDEVDFTASLSEAEIAKYCLAKGEIIPVVYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJE4</accession>
    <name>A0A5C6ZJE4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Rhodanese-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_04845</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="27"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="115" mass="12933" checksum="62FA6EA307A49215" modified="2019-11-13" version="1">MSCTSVNAQDPETITVLNATDFQKAIQQKNIKLVDVRTAEEYKVGAIDDAVNIDFLQPETFENQFEKLDRKTAVFIYCRSGNRSGKAALKLKAMGFEAIYDLEGGFMNWANKDLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJH7</accession>
    <name>A0A5C6ZJH7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_09140</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="212" mass="23925" checksum="6DAB618DED9D993F" modified="2019-11-13" version="1">MIQAAVISNGLQGIHRYFVSNEKVNYSVLEIEEDFNPDLTPYDLLVVPNGCDHIAMAKIKDKVASFLEEGNALFCFDGWFTNWIPGNQWVMSNEKKTIDIRYKVKTDTYNLFEGIDIDKLIYNHNISGWWACGYIDASKNADVIVEDTWQRPIIVLDEKTTNGTIILTASGPLGDSGAIPTDDESSYSVLGQLYQNMLSLIIKKINHETSMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJI9</accession>
    <name>A0A5C6ZJI9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022837497" evidence="1">
        <location>
            <begin position="24"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="155" mass="18223" checksum="36862348D87CD264" modified="2019-11-13" version="1">MKTHKKRIIGVFILFLMVSCALESQFALPNDEKINPEFIGEWYSEENDDESIKITKNGEKSYRLQVFDENETNESIAFSKTIKGFSIMNIQTETKGIITYVFYGFNVEGNTLTFSEVNDKLRHEEFESESELLRFFEENLTKEDFFINPTELKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJU5</accession>
    <name>A0A5C6ZJU5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ComF family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08465</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pribosyltran" evidence="1">
        <location>
            <begin position="166"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="226" mass="25476" checksum="5B67BD9A5276DBA6" modified="2019-11-13" version="1">MLNNLLNLFFPKVCYACSNILSDNELHMCTQCRHDLPLTNFHGDHENAVHKVLYGRVKLINATALLHFSKKGIVQQLMHNLKYRGHEQIGHILGLWLGEELKHLKEYSAVEIVVPVPLHKSKLKKRGYNQVEKFGKALALALNAGYEDQSLIKITNTKTQVFKDRLKRGSAIDANFAIQNQEYLAQKHILLVDDIITTGATIEACANELLKIKGVRLSLAVMAITD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK54</accession>
    <name>A0A5C6ZK54_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2306 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05570</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018750">
        <property type="entry name" value="DUF2306_membrane"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10067">
        <property type="entry name" value="DUF2306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="166"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="208"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="238"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="267" mass="29792" checksum="60E1F0C718BA1A67" modified="2019-11-13" version="1">MRLSQSSIPERVLGISTTLLFVVIFLGQFIFALYILGLYGISGLAGDFERWNTAAPHGYDKNDITGNIFFGMHMALAAVITIGGPLQLIKGLRNRFRKLHRISGRIYITCAFLISLAGFYLVWVKGSVGGLVGSIFISFNGTLIFICAFYALKKALNKQFSEHQKWAIRLFLVMSGVWFFRVFLMLWLTIFKGPVGFDPIAFQGPALVFLYMLSYLCPILLAEYYFRTVKKSNINKVVGAVLLLIITVGVSIGSFAATMGLWLPNIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK90</accession>
    <name>A0A5C6ZK90_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">T9SS type B sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_04450</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026341">
        <property type="entry name" value="Bac_Flav_CTERM"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04131">
        <property type="entry name" value="Bac_Flav_CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023062627" evidence="2">
        <location>
            <begin position="30"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="817" mass="89832" checksum="F13942D052A61E93" modified="2019-11-13" version="1">MQQNPIFFKTYVFLIFIFGIFSVSVSAQAPNDCQFAVIVCGNSSLSVDVSGVGSQELNNSNTCQSQENNSIWLTVNIATSGTLGFTLTPQSTNINEDYDFFVFGPNVSCGNIGQAIRCSTTNPAASNQGNNLTGMNAASTETSEGPGDLGNSFVKQLDVLAGESYFIVIDRPVGNSPFSLEWTGTATFPDNPSNPLTQEETNLEICDNLVPFSDGIAQVDINALKTTITNGELDKMVSFHSSESDAILNTDALSTVFENTASPQTYFIRIENSITGCFILNEFTLTVNTLSNFNTPSNFELCDDETDGNAFNGQTRFDFNLKTEEIIANIPDIDYSINYYSSLSDAQTETAALPLNYDNTAPTPIEVFVRIDDNTSNCVAITSFNLEVLEIPVANDISIIQCDEDGLPEGFTLYDLTDYSEFISDDEPNRDLKFYTSMADLENDEDEIDATAFTNDVSPQIVFALVINTQTGCSNTAEVTLETSSTASNDTSLEACDYDGTEDGFYNFDLQDAEAAILLGLPIDLNLSYYETYENALTETDVLGNSFTNSIPYNQTIYARVENANACFGISKIELIVYELPNLLPEETVYYCLNTFPQTSTLTGGLIESLPNNYYYEWSTGETTSEIEINAAGTYSVRVTTTDGCFKDRTITVLPSNIATITNIEITDASSNNSISVLVSGEGSYQYALDNPNGLYQDSNVFENVPFGFHTVYVRDVKNNCGIVDKLVSVIGFPKYFTPNGDTYNPYWQVKGISSNFQPDSQILIYDRMGKLLKELDPLGPGWDGTWNGQLMPSSDYWFVVKLQDGRTFKGHFSLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKD9</accession>
    <name>A0A5C6ZKD9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_02190</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00614">
        <property type="entry name" value="CGS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006235">
        <property type="entry name" value="OAc-hSer/O-AcSer_sulfhydrylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01326">
        <property type="entry name" value="OAH_OAS_sulfhy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="3">
        <location>
            <position position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="430" mass="45928" checksum="D1F37C579F4A7C81" modified="2019-11-13" version="1">MSTQKFATKALHAGHDVSQNGGTRAVPIYQTTSYVFDNSDDAAGRFNLSVPGYIYTRLNNPTNDVLEQRLAALEGGIAAVVTASGASAISTTLLTLLRAGDHIVASSSLYGGTYNLLSVTLPRHGVTTTFVDASDPENFNKAAKENTRAFFVESLGNPKLDVLDLEKISKAAKAHKVPFIVDNTVATPYLTNPIAHGANIVIHSLTKYISGNGTSLGGAIIDAGTFDWANGKFPEFTEPSAGYHGLVYSEAIGDAAFIAKLRIEGLRDYGAALSPFNAFQIIQGLETLEIRIKKHSENALALAKWLEQQDEVEWVNYPGLESSAYKALAEKYLPEGQSGIVTFGAKGGFESAKKIADTTKIFSLLANIGDTKSLIIHPASTTHQQLSDEAQEGAGVTKDLVRLSVGIENIDDLKADLKAAFAHIDKKVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKN9</accession>
    <name>A0A5C6ZKN9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DoxX family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="124" mass="14097" checksum="5EE9ACC134407D48" modified="2019-11-13" version="1">MKSILNLGKWLFILPFAVFGFLHFGPIEFTIDYIPEYLPFKIFWIYFSGACLIAFAVSAAIKKFDKLASVLLALELILFVFLIHIPKAMEGDFVQFIGIFRDTAMAGAALIYAKFVATDQRFIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKT6</accession>
    <name>A0A5C6ZKT6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Lrp/AsnC family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_07525</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13404">
        <property type="entry name" value="HTH_AsnC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00033">
        <property type="entry name" value="HTHASNC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD89627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="135" mass="15288" checksum="2EA892CEC63DD282" modified="2019-11-13" version="1">MDDIDLKILEMLRKNARESLANIGKSVELSAPAIGKRVKQLEEKGIILGYSLKLNHEKLGIRTKAYIILKIHQSSTLKTAYNQIAHLTEVQRCDRITGDDCLCILAFFKDNKELITFLERISQYGVPNTSILLES</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL40</accession>
    <name>A0A5C6ZL40_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha-amlyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_02870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015171">
        <property type="entry name" value="Cyc-maltodext_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019492">
        <property type="entry name" value="Cyclo-malto-dextrinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10438">
        <property type="entry name" value="Cyc-maltodext_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09087">
        <property type="entry name" value="Cyc-maltodext_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aamy" evidence="1">
        <location>
            <begin position="143"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="642" mass="73207" checksum="31442F8856590E0F" modified="2019-11-13" version="1">MLLLLLLISFTCKASEPNLQLENAQTKDAISNGGDVDRIEPPNWWIDFETDALQLLVHHPDIGDYSPSISYEGVEIVKVTKAGQSPNYLFIDLIISKNTSSGTFPITFKNADGQVLIQDYELKSRQKPAGAYVGFNSSDAIYMLTPDRFANANPENDRIAGMNETKVDRANGYARHGGDIQGITQHLDYISNLGFTAIWPSPLLTNDMKSASYHGYAMTDFYQVDPRFGTLSEYRQLATQAQNKGIKLIMDQVANHCGLYHWWMRDLPFKDWVNLQENFEKHREHWDNAHTINASHRRTTNQDLYASQYDKDGNSEGWFVSTMPDLNQRNPFMATYLIQNSIWWIETLGLGGIRQDTYPYPDKQFMSDWAAAIMTEYPNFSIVGEEWSLNPLLIGYWQQGAENADGYQSHLRSTMDFAMQLNVVEALNETESWDKGLVKIYEGLANDFHYASPKDIMVFGDNHDMSRIFTQLDGDVANTKMAIATYAVLPRIFQMYYGTEILMDDFENPGDHGLIRTDFPGGWDGDAKNAFSGKNISAEEKDMQRFVSELLNFRKNSKAIHEGETMHFAPFDGVYFLFRIQGDETVVLILNKNEKPISIDLNRFSEMGLNGKTLRNIFSEDQVIWKKEMTIEKKGVQVLTTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL67</accession>
    <name>A0A5C6ZL67_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_05155</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="74" mass="8700" checksum="738733C3A73186EB" modified="2019-11-13" version="1">MLKNLNKIHADLFDDLEDSILAHEKLLARIEKSEKGLSDADYRSQHQHLFLKMNTFTSDFKSFKKIVFGYVKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLA4</accession>
    <name>A0A5C6ZLA4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TolC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_04440</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022821799" evidence="2">
        <location>
            <begin position="25"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="439" mass="49359" checksum="A960CFAE12E2DC0E" modified="2019-11-13" version="1">MKPYKLWSLFLSACLGICALQTYAQEVLTLEAAVEIALENNYEIRLAENDLKVDSLGVSPGFAGMLPRVFADASGNNSTQNISQTRSDGSVVELDNAKNNNLNYGVGLDWTIFDGLSMFARYDRLKELQKLGKAELQSTVLGRASDVMITYYDLVQQQQQLTALDSTLVISQQRVDLADNRFSIGKASKLEVLNAQVDLNTDRTLQIRQIEMYANTKIRLNEIMARDTQIDFKVNDEVLIANNLKLDELERLASTQNPELQAQLIAKRISELELKQIKRNRYPVITANTGYNFSDSEFSLGFATENRAQGWNYGFTASIDIFNGSNQNRNEKIAKLQIETTTIAIEQQTQTINSQLQTAFQTYITNLSLIELETKNEEIAKENLDITLAKYKIGTIPTIEFRTAQLNYINATLRLSNAIYLAKLSEITLKQLSGNLSLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLI6</accession>
    <name>A0A5C6ZLI6_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminotransferase</fullName>
            <ecNumber evidence="1">2.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_05895</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.-" evidence="1"/>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="2">
        <location>
            <begin position="35"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="396" mass="44347" checksum="2D3E8DB1B89D035B" modified="2019-11-13" version="1">MPKISEKGQSMPQSPIRKLVPFAEAAYKKGKIVYHLNIGQPDIKTPEIAMDAVRVHSLDILSYTRSEGSEEYRKKIAKYYAKNSIDVNHDDIIVTTGGSEALLFAFGSIMDSDDEIIIPEPFYANYNGFSIASDVKVVPVISKFEDNFALPEIAEFEKLITPKTKAILICNPGNPTGYLYSKEEIKKLAEIAVKHDLFIIADEVYREFVYDDKEFYSIMQEESLKEHAIMIDSVSKRYSMCGARIGYLVSRNKEVIATALKFAQARLSPPTLAQIASEAALDTPQSYFDDVIEEYVERRNVLIEELEKIDGVKVAKPQGAFYCIAELPINNADKFAQWLLEEFDVDGETVMVAPAAGFYSTNNVGQNQVRLAYVLNKASLVKAVAILGKALKVYRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLP7</accession>
    <name>A0A5C6ZLP7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nucleoid-associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_01740</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the YejK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009295">
        <property type="term" value="C:nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007358">
        <property type="entry name" value="Nucleoid_associated_NdpA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04245">
        <property type="entry name" value="NA37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="349" mass="40751" checksum="E572989F55320D97" modified="2019-11-13" version="1">MIKRNKASISKCILHKVGNKFNSTKNAFSEQPIDFDEESYDILVPYLLRPFGNLSETYRFNHHSNVDLNEINSYASQLLKDDSEFVDISKHIVTHLFEQSNSSQIKIGDVIICMVHDLQYEDYETDAIGIFKIENKTHFFQTYLENNSYDIIAQKGIGTKKVDKGCLILNAADGEGKIVLSVDNNNYDAQYWIKSFLNVKYPDDSNEHTKNYIEMCRDFSKDVMQAQFGGQEKSNFLAKTVDFFKENEIANIETFKEEIIADEDRIQLFEDYKKVYETDHNVLIRNQFDVSDIVLKKQKQKIKTEIKLDTNIQIKLDVDAPDASEEFLERGYDEVKKMHFYKVFFNEEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLU1</accession>
    <name>A0A5C6ZLU1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Ferritin-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_02020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="273" mass="29533" checksum="F2DE8FF69F87E29E" modified="2019-11-13" version="1">MDFIKLLDSLSNKDLLNKKGSRRESFGQFSKFGKNMALASIPFGLAATSSKAGAATKKMASAAFMADNNDVLNFALTLEYLERNFYQIALDTNGLIPAEDRVVFETIYRHEKSHVDFFSAALGPNAIDEPTFDFSGAQAGLDLPTFTDYPTFMALAQGFEDTGVRAFKGQAGALANDNELLTFALQVHSVEARHASQVRRMRGSKGWITQAENNLPAPFAPIYAGEANTVQGGVDLAGMFSDFGGNDAVTEAFDEPLTMDEVLTIGGIFIVPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM15</accession>
    <name>A0A5C6ZM15_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Na(+)-translocating NADH-quinone reductase subunit F</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_06075</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="149" mass="16988" checksum="99996535C22CEDBC" modified="2019-11-13" version="1">MSNRLEKAIEKLYVAFHNNTLHPECCKSCAVGNILDNKDSWKHLSDDHGSLQLNYLGKVHQGLGRRFNGYTPQELLQVEASFLAACDYELPFRHNHKKPKNPTDKDLLFKGLCAVISFLCKLDHVPNVMDYTKLFEVENDKPKFALALA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM34</accession>
    <name>A0A5C6ZM34_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_02000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022739235" evidence="2">
        <location>
            <begin position="23"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="32"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="362" mass="41530" checksum="47B36E2CA35C2CD3" modified="2019-11-13" version="1">MTTITKYVVLGLLCLISLEISAQEQQADSLKIAQTSNRIKSLVELKERIETEEREFLKSEVEAINARLEDDKITKDEAEALKSEAAQKRAQNIENRLAIIDNKIALLERNPEIDSDEQKNAITITFRGENDEEDISIWSIEKNKSKPKVYDERTYSNLVFAIGVNNAIIDGESLGDTYSFLGSGFVELGVAWNTRVLKNSNAIRFKYGLSFQWNKFSPKDDQYFEQNGNSTTLETFPSELRQSQFRVTNVVVPIFFEFGPSKKIEKEDYFRYTTHKQVKFGVGAYGGFNIGTQQKLKYKEDGDRVKQKIRRNYNTSDFVYGLSAYIGIDEISLYAKYDLNTVFKDQLIDQNNVSLGVRFDFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMB2</accession>
    <name>A0A5C6ZMB2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminoacyl-histidine dipeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03995</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03890">
        <property type="entry name" value="M20_pepD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001160">
        <property type="entry name" value="Peptidase_M20C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43501">
        <property type="entry name" value="PTHR43501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016599">
        <property type="entry name" value="Xaa-His_dipept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00934">
        <property type="entry name" value="XHISDIPTASE"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01893">
        <property type="entry name" value="aa-his-dipept"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="1">
        <location>
            <begin position="204"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="487" mass="53550" checksum="959658FE2D94C79D" modified="2019-11-13" version="1">MNEAIRELEPKALWNKFADLNAVPRPSKKEERVIQFMTDFGKSLNLETVIDGVGNVIIKKPASAGMEDRKAIVLQSHLDMVHQKNNDTNFDFDTQGIDMKIEGDWVKAKGTTLGADNGLGVATIMAILESKDIEHPAIEALFTIDEETGMTGAMGLKGAVLKGDILLNLDTEEDDEIGVGCAGGVDVTASRTYKLEETPEFKTGFKITVKGLQGGHSGMQIHEGLGNANKIMNRVLFDGFENYGLRISEIDGGSLRNAIPRESNAIVVIDQIHEEAFQSDLKDLETEIKTELKTMEPDLKIEVSQIETPKHIMDLGVQEGLTRALYAALNGVYRMSADIPDLVETSNNIAKVIVKDGEITIKCLTRSSVESSKWDLANALRATFELTGCEVEFNGEYPGWKPNMDSDILKVLVPLYKKLNDGEEPHVAACHAGLECGILGQNYPDMDMISFGPTIKGAHSPDERAQISSAQKYWKFVLEILKNIPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMC6</accession>
    <name>A0A5C6ZMC6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Antibiotic biosynthesis monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_01165</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007138">
        <property type="entry name" value="ABM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03992">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51725">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABM" evidence="1">
        <location>
            <begin position="2"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="98" mass="11985" checksum="FD6589153A3B2FC3" modified="2019-11-13" version="1">MLIRIVKMSFEPSKIQEFLMNFDANKRQIRAFEGCEFLELYRDKNNKDLFFTYSYWQTEADLEHYRHSELFKKVWSKTKPLFNAKPEAWSVNRLHSLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMT4</accession>
    <name>A0A5C6ZMT4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Four helix bundle protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_01910</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16377">
        <property type="entry name" value="23S_rRNA_IVP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012657">
        <property type="entry name" value="23S_rRNA-intervening_sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036583">
        <property type="entry name" value="23S_rRNA_IVS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38471">
        <property type="entry name" value="PTHR38471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05635">
        <property type="entry name" value="23S_rRNA_IVP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158446">
        <property type="entry name" value="SSF158446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02436">
        <property type="entry name" value="TIGR02436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="126" mass="14714" checksum="D51E00DF2C4D252F" modified="2019-11-13" version="1">MKSNYHFKFEDLQVYQKAMDFGETVDALVKKFPNHELYALSSQFRRASDSIALNIAEGYPGSDAQFVKHLNHAIYSANECVSCSTKAKRRSYFEFETDEENRKMLSELTKMMSSLMRKILERNQHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMW6</accession>
    <name>A0A5C6ZMW6_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Asparagine--tRNA ligase</fullName>
            <ecNumber evidence="5">6.1.1.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Asparaginyl-tRNA synthetase</fullName>
            <shortName evidence="5">AsnRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">asnS</name>
        <name evidence="7" type="ORF">ESY86_02065</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + L-asparagine + tRNA(Asn) = AMP + diphosphate + H(+) + L-asparaginyl-tRNA(Asn)</text>
            <dbReference type="Rhea" id="RHEA:11180"/>
            <dbReference type="Rhea" id="RHEA-COMP:9659"/>
            <dbReference type="Rhea" id="RHEA-COMP:9674"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58048"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78515"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.22"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.22" evidence="5"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004816">
        <property type="term" value="F:asparagine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006421">
        <property type="term" value="P:asparaginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00534">
        <property type="entry name" value="Asn_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004522">
        <property type="entry name" value="Asn-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00457">
        <property type="entry name" value="asnS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 5 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="6">
        <location>
            <begin position="130"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD90770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="476" mass="54449" checksum="98A1EAD704AEE594" modified="2019-11-13" version="1">MTYSVSQLLKQDLPLQPIEINGWVRTFRANRFIALNDGSTLNNIQCVVDFEQTDAAILKRITTGAAVHIEGELVESQGKGQKVEIKVNSIAILGDSHPDDYPIQPKKHSFEFLRENAHLRTRTNTFSAVMRLRSSLSFAIHKYFNDNGFYHVHTPIITGSDAEGAGEMFRVSNLDAKNPPLNKDGSVNYKEDFFGKETNLTVSGQLEAESYAMSLGKVYTFGPTFRAENSNTSRHLAEFWMIEPEVAFMDLAGNMDLAEAFMKSVLNYVLEHNREDLEFLEQRLLDEEKTKPAADRSEMSLIDKIKFVVDNNFKRVSYTEAIDILKDSKPNKKKKFKYIIEEWGADLQSEHERFLVEKHFKCPVILFDYPANIKAFYMRLNEDGKTVRAMDILFPGIGEMVGGSQREERLEVLKEKMKALDIDEKELWWYLDLRKYGTAVHSGFGLGFERLVMFATGMGNIRDVIPFPRTPQNADF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMY6</accession>
    <name>A0A5C6ZMY6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF192 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_04600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.1140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003795">
        <property type="entry name" value="DUF192"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038695">
        <property type="entry name" value="Saro_0823-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37953">
        <property type="entry name" value="PTHR37953"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02643">
        <property type="entry name" value="DUF192"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="169" mass="18952" checksum="F34B73ACC06A42A3" modified="2019-11-13" version="1">MLKKHVLKIALFCGFGIIFLPFNGCKEESKASAIKPIEVKFQKEGELQLKKAKTDSLLVSLDIEIADDDYQTQTGLMYRHSMAANRGMLFIFPESEMRSFYMKNTQFALDIIYIDEKKTIVSIQKNAKAMDEGSLPSEAPAKYVLEVNAGLSDAWGLELGDLAVFDLND</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMZ8</accession>
    <name>A0A5C6ZMZ8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Octanoyltransferase</fullName>
            <ecNumber evidence="6 7">2.3.1.181</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Lipoate-protein ligase B</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Lipoyl/octanoyl transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Octanoyl-[acyl-carrier-protein]-protein N-octanoyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 12" type="primary">lipB</name>
        <name evidence="12" type="ORF">ESY86_01750</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6 7">Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6 7">
            <text>L-lysyl-[protein] + octanoyl-[ACP] = H(+) + holo-[ACP] + N(6)-octanoyl-L-lysyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17665"/>
            <dbReference type="Rhea" id="RHEA-COMP:9636"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:9928"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78463"/>
            <dbReference type="ChEBI" id="CHEBI:78809"/>
            <dbReference type="EC" id="2.3.1.181"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 6 7">Protein modification; protein lipoylation via endogenous pathway; protein N(6)-(lipoyl)lysine from octanoyl-[acyl-carrier-protein]: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="6">In the reaction, the free carboxyl group of octanoic acid is attached via an amide linkage to the epsilon-amino group of a specific lysine residue of lipoyl domains of lipoate-dependent enzymes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the LipB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.181" evidence="6 7"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00538">
        <property type="reaction ID" value="UER00592"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033819">
        <property type="term" value="F:lipoyl(octanoyl) transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16444">
        <property type="entry name" value="LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00013">
        <property type="entry name" value="LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000544">
        <property type="entry name" value="Octanoyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020605">
        <property type="entry name" value="Octanoyltransferase_CS"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016262">
        <property type="entry name" value="LPLase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00214">
        <property type="entry name" value="lipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01313">
        <property type="entry name" value="LIPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="11">
        <location>
            <begin position="43"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6 9">
        <location>
            <begin position="88"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6 9">
        <location>
            <begin position="160"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6 9">
        <location>
            <begin position="173"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="6 8">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <feature type="site" description="Lowers pKa of active site Cys" evidence="6 10">
        <location>
            <position position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR016262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR016262-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR016262-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR016262-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TXD90714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="232" mass="26243" checksum="1101423D8CF002E0" modified="2019-11-13" version="1">MNKQINIEDLGTKDFKDTWDYQEQLFQSILDVKIKNRREATAMQTTNYFLFVEHPHVYTLGKSGEMSNLLLNEAQLEQKGATFYKINRGGDITYHGPGQIVGYPILDLDNFFTDIHKYLRLLEEMIILTLAEYGLETERSPGETGVWLGVGTPFARKICALGVRASRWVTMHGFALNVNADLGYFDNIVPCGIKGKAVTSLNVELGVERISETEVKAKLLKHFMVLFEGNNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN08</accession>
    <name>A0A5C6ZN08_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidoglycan hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_01815</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004040">
        <property type="term" value="F:amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019835">
        <property type="term" value="P:cytolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042742">
        <property type="term" value="P:defense response to bacterium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002901">
        <property type="entry name" value="MGlyc_endo_b_GlcNAc-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01832">
        <property type="entry name" value="Glucosaminidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00047">
        <property type="entry name" value="LYZ2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="SSF54106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0929">Antimicrobial</keyword>
    <keyword evidence="2" id="KW-0081">Bacteriolytic enzyme</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LysM" evidence="4">
        <location>
            <begin position="224"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00032108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="268" mass="30896" checksum="36C72E7C336C3A56" modified="2019-11-13" version="1">MKKLLILLLLGLFVLSCGSKKRIVTKKRNSKPKTERVVIEPSKRPVEQEIEVRPNVPELPKKVYANATEEYIGNFSDIAMIEMRKYKIPASITLAQGILESGSGKGRLSVEGNNHFGIKCHGWTGKEIYHDDDRHQECFRKYDYAISSFEDHSIFLTSRGRYSKLFDLRQDDYEGWAKGLRAAGYATDRKYPEKLISLIERYKLYEYDDLVLDQKREVIATSNISHEVVKGDTLYGLSKRYNTTVELLKRLNKLKNNDISLGQILIIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN66</accession>
    <name>A0A5C6ZN66_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Four helix bundle protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_02790</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16377">
        <property type="entry name" value="23S_rRNA_IVP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012657">
        <property type="entry name" value="23S_rRNA-intervening_sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036583">
        <property type="entry name" value="23S_rRNA_IVS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38471">
        <property type="entry name" value="PTHR38471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05635">
        <property type="entry name" value="23S_rRNA_IVP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158446">
        <property type="entry name" value="SSF158446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02436">
        <property type="entry name" value="TIGR02436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="124" mass="14651" checksum="15992F5F368FFFF4" modified="2019-11-13" version="1">MEMIKSYKDLKVHQAAFSLAMELCWLTRKFPKEEIHSLRSQVVRCSRTVSANISEGWAKREYEAVFKQQLINALGSNAETENWLNYAIECKYIEQSVFERVLKQNDEIGKMLTKLHKNWTTYEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNA2</accession>
    <name>A0A5C6ZNA2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type 1 glutamine amidotransferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_03070</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DJ-1_PfpI" evidence="2">
        <location>
            <begin position="26"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="225" mass="24595" checksum="25DE9B60D3DFF5AD" modified="2019-11-13" version="1">MNVLFVLTSHDKLGDTGNKTGFWVEEFAAPYYTLVDKGVTITVATPKGGKAPIDPTSASADAQTEDTERFDRDEEAQKLINNTVKLDTLKAEDFDAVFYPGGHGPLWDLSEDKTSKALIEAFNKQEKTIAFVCHAPAALKNVKNENGEPLVKGKKVTGFTNTEEEAVQLTKVVPFLVEDMLKENGGTYSKAADWEVHVVKDGNLITGQNPASSNKVAELLYETLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNF0</accession>
    <name>A0A5C6ZNF0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphatase PAP2 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00720</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxi_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="SSF48317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="acidPPc" evidence="1">
        <location>
            <begin position="139"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="283" mass="31487" checksum="2DB37F325A50C8B6" modified="2019-11-13" version="1">MKTIYINTWLTLLLVAQLSYGQSLESKKDKDTTSIWQLMKHDATYTAKGVGYSLSRPIYWKAKDFTKMGTLIAGTALLSLADDPVRDFASNGREHVPEILRDFGWYFGSPQNYFMANAGLYGFGLLTKNEQVRKTSVLIITSSITSGLIQSFTKTAIGRARPGTELGNHSFSPFSKEGRFHSFPSGHTILSVTMAHSIAKQFDNIWIKTGIYAIGAIPPMSRLIDDAHWITDIAFSTALSIIIVDGVDKFLFNEDAYNYPKRPKTISWNITFGSNTIGVVGQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNG2</accession>
    <name>A0A5C6ZNG2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Electron transfer flavoprotein subunit beta/FixA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_02525</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01714">
        <property type="entry name" value="ETF_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014730">
        <property type="entry name" value="ETF_a/b_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012255">
        <property type="entry name" value="ETF_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033948">
        <property type="entry name" value="ETF_beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21294">
        <property type="entry name" value="PTHR21294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01012">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000090">
        <property type="entry name" value="Beta-ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00893">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ETF" evidence="1">
        <location>
            <begin position="23"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="248" mass="26849" checksum="F2E592D9938494D7" modified="2019-11-13" version="1">MKILVCISHVPDTTSKINFTDDNTKFDTNGVQFVINPNDEFGLTRAMWFKEKQGASVDVVTVGGPETEPTLRKALAIGADSAIRVNSEAKDGYQVAKELAKVVKDGGYDLIIAGRESIDYNGGMVPGMLAALIDANFVTNCINLEIDGDNVKAMREIDGGKETVSTSLPLVIGGQKGLVEESDLRIPNMRGIMMARKKPMNVLEPSNAETETASVKFEKPEPKGQITLVDADNLDQLVDLLHNEAKVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNH0</accession>
    <name>A0A5C6ZNH0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05695</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022944667" evidence="1">
        <location>
            <begin position="23"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="147" mass="16119" checksum="3781C3CF42BC2767" modified="2019-11-13" version="1">MFSKLPKYLILCLCFAFLFVNSKCSDDDEVDGNCGPAAVIDYGYYNAAESNNYDMVSANITGNCLNVEIAASGCDGSNWSLVLLDSGDIAESNPVQRDLKLVFSNLEDCQAFVSQTRVFDLANLQTPEDHSVILNIDGLDESLTYIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNJ0</accession>
    <name>A0A5C6ZNJ0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA metabolism protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00255</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023875">
        <property type="entry name" value="DNA_metab_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025404">
        <property type="entry name" value="DUF4130"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13566">
        <property type="entry name" value="DUF4130"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03915">
        <property type="entry name" value="SAM_7_link_chp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4130" evidence="1">
        <location>
            <begin position="87"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="257" mass="30284" checksum="AD57E67D1584B9F4" modified="2019-11-13" version="1">MKQRHLLYDGTFDGFLSCVFYAFEHKLKQLSIKKASSCQNGLFSEPETIVTDEQKANRVWKGLQSKLSKRGCLSLYYAFLSEQVGVEQVLLDYIQYAFANLFEVDTDFSHPSVLATSKLAKSVGREKHRMEAFVRFRLTKDDLYFASIEPDFNVLPLISKHFERRYADQKWVIYDIKRKYGLLYDGHSVEIMTIDFPANFDFTKTESDFFTEQELEFQTLWQSYFKSTNIASRKNMTLHVKHVPKRYWKYLSEKQPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNN5</accession>
    <name>A0A5C6ZNN5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Virulence RhuM family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_04390</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011204">
        <property type="entry name" value="Virulence_RhuM-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13310">
        <property type="entry name" value="Virulence_RhuM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015268">
        <property type="entry name" value="Virulence_RhuM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="336" mass="38955" checksum="72B9E1E154217F3F" modified="2019-11-13" version="1">MSNKEENNIIIYTTQDGKSSVALFARDGNVWMNQKQLAELFDTSVPNISMHIASILKDKELNPDSVVKDYLTTAVDNKEYNVTFYALDMILAIGYRVRSKRGVQFRQWATRNLSEFVIKGFVMDDERLKNPDGRADYFDELLERIRDIRASEKRFYQKVRDLFSLSSDYDPTDKATQMFFAEAQNKLLYATTNQTAASLIVKRADAATLNMGLSTWKGSVVRKQDITVAKNYLTEDELDSLNRLVVIFLETAELRAKNKQDLTMRFWQNNLDKIIEFNDLQVLNNAGKVSHKQMEKKVRAHYEVYDNKRKKGAAEEADRIDLEDLKSLEQKIKRQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPA6</accession>
    <name>A0A5C6ZPA6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_02485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="5"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="63" mass="7257" checksum="14BD70F39E4AB60F" modified="2019-11-13" version="1">MKNKIKAPRAEHELTQEQLAVKVDVSRQTINAIEKGKFDPSLPLAFKISKLFKMSIEEIFQNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPT2</accession>
    <name>A0A5C6ZPT2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SLC45 family MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_02855</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="241"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="303"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="334"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="357"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="391"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="424"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="461" mass="50975" checksum="CDCB992D3207AB1E" modified="2019-11-13" version="1">MKKRALGFWEIWNMSFGFLGIQFGFALQGGFMSRIFQTLGAEKDAIPLLWIAAPLTGLLVQPIIGYMSDRTWSPKWGRRRPYFLVGAVLSSIALFFMPHSPALWMAAGFLWILDASINVSMEPFRALVADKLPESQRSYGFVVQTLIIGIGTWIASNLPWMVSQLGVSNSADLGVVPMSVKVAFAIGAFVFMASILYTVFTTTEYPPEDMEEFEREKAERNKFIPNILNNIGNMPLTMKKLGVIQFFSWFAFFTMWSLANPALTEHVYKAPAPIENSYDMTVVAQAAKFNVENTNFQEASNSVGSAMGIYGLSSMAFALLLTLYTSKKNINRKYVHLFSLIVGGLGFLGMYYATPDTLLYCFILVGVAWGSILSMPYAMLSSSVDPKKMGVIMGIFNMFIVIPQIIAALGGINYVSSLLGEEAINAMTVAGISLMIAGLCNLLITDKNAIKYQPELTEIHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPW8</accession>
    <name>A0A5C6ZPW8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glutamate-1-semialdehyde 2,1-aminomutase</fullName>
            <shortName evidence="7">GSA</shortName>
            <ecNumber evidence="7">5.4.3.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Glutamate-1-semialdehyde aminotransferase</fullName>
            <shortName evidence="7">GSA-AT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">hemL</name>
        <name evidence="9" type="ORF">ESY86_01810</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(S)-4-amino-5-oxopentanoate = 5-aminolevulinate</text>
            <dbReference type="Rhea" id="RHEA:14265"/>
            <dbReference type="ChEBI" id="CHEBI:57501"/>
            <dbReference type="ChEBI" id="CHEBI:356416"/>
            <dbReference type="EC" id="5.4.3.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; 5-aminolevulinate from L-glutamyl-tRNA(Glu): step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.3.8" evidence="7"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00317"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042286">
        <property type="term" value="F:glutamate-1-semialdehyde 2,1-aminomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00375">
        <property type="entry name" value="HemL_aminotrans_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004639">
        <property type="entry name" value="4pyrrol_synth_GluAld_NH2Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00713">
        <property type="entry name" value="hemL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 7" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="4 7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7">
        <location>
            <position position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD90723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="428" mass="46214" checksum="036F893465423D3D" modified="2019-11-13" version="1">MLYQRSSALFKEAEKYIPGGVNSPVRAFKAVGGTPIFAKSAKGAYVFDEDGNRYIDYISSWGPMILGHAFEPVVNAVIAKAKDGTSYGMPTEIETKIAKLAVEMVPNIDKIRFVNSGTEACMSAVRLARGFTDRDKIIKFAGCYHGHSDSFLIEAGSGAVTFGSPNSPGVTQNTAKDTLMAIYNDIDSVKTLIEANANEISCIIIEPVAGNMGCIPPKKNFLKQLRTLCDAHNILLVFDEVMTGFRLAKGGVQELYGVNADIVCFGKVIGGGLPVGAFAARDEIMQHLAPLGSVYQGGTLSGNPLAMAAGLAMLETIAEDQELFKRLADKTEYLHKGCAKALNKHKIPHVINREGSMISIHFTIGEVVDFKTAALGNNERFKQFFHGMLAEGVYLPPSAFESYFLNDALSYEDLDATIKAVEKVASTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZQM3</accession>
    <name>A0A5C6ZQM3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Fe(3+) ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_02975</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055072">
        <property type="term" value="P:iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026045">
        <property type="entry name" value="Ferric-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002825">
        <property type="entry name" value="CfbpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0410">Iron transport</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR002825-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD90933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="351" mass="39020" checksum="372DA4693F6D7484" modified="2019-11-13" version="1">MKNLILAVAAFSILAACKNESEKKDNATAEEMAKDQVVNVYTHRHYEPDQNIFKMFEEKTGIKVKVINASADELIQKMKMEGKQSPADVLITVDAGRLSRAKDEGLLQSVESEVLENAIPSYLRDVDNQWFGLTKRARIIAYAKDRVNPEDLSTYEDLVNEKWEGKILVRSSSNIYNQSLMASIIANNGEEEAKRWAEGIVANMARSPKGSDRDQVKAVVAGEGDLAFVNSYYIGKMLNSPDAEEVKTAQQIGLFFPNQEGRGTHVNVSGAGVAKYAPNKENAIRFIEFLISEEAQQIFTDANYEYPIIESVAPVKDIKAWGAFKEDTLGLNKLGANNKKAVLIFDEAGWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZR03</accession>
    <name>A0A5C6ZR03_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">YihY/virulence factor BrkB family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_00125</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017039">
        <property type="entry name" value="Virul_fac_BrkB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30213">
        <property type="entry name" value="PTHR30213"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03631">
        <property type="entry name" value="Virul_fac_BrkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF035875">
        <property type="entry name" value="RNase_BN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00765">
        <property type="entry name" value="yihY_not_rbn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="57"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="120"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="160"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="207"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="245"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="274"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD91323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="315" mass="36253" checksum="37D959172D20CB54" modified="2019-11-13" version="1">MEDSIESRLERTPVIKQFIKLLKFIKLPALEGLTLYDFLRIYIKGIIKGTITSRASAIAFSFFTAIFPFLLFVIILIPYIPVKGFETEFRAFLNSVLPPQTSEFFFENIFQNIKGDTAGLISTVFVLSLFLMANGISALFSGFESSYHQQLTRSIVKQYLYSIGVALILTILLIVSIAVLGYFQLYVVKEIMQVFERQGYEMEKWAVFWSNVVKFVFFIVMIYLATATLYYFGTKEGKHSRFFSAGALLTTILIILFSYLFGIYITYFSTYNQLYGSIGALLIILFYLWLNSNLLLLGFELNATIRRLKRKNDNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-02-10" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZR89</accession>
    <name>A0A5C6ZR89_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GPW/gp25 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00505</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007048">
        <property type="entry name" value="IraD/Gp25-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04965">
        <property type="entry name" value="GPW_gp25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GPW_gp25" evidence="1">
        <location>
            <begin position="28"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="136" mass="15707" checksum="A13CCFAC5347D247" modified="2019-11-13" version="1">MEEKQFLGTGWSFPPTFNKTQKSLITVSGELDIEQSLELLITTSPGERVLRSDYGCGIKAMSFENMTVTMMTKLKRLIEKSILKYEPRIDLENVSLKNSIELEGILYIQIHYRLRTTNSRSNFVYPFYIKEGSLVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZRT9</accession>
    <name>A0A5C6ZRT9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glucose 1-dehydrogenase</fullName>
            <ecNumber evidence="1">1.1.1.47</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_01580</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.47" evidence="1"/>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047936">
        <property type="term" value="F:glucose 1-dehydrogenase [NAD(P)] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="258" mass="27502" checksum="A8E0769044B2B34C" modified="2019-11-13" version="1">MSSIKSKFNLTGKVAIVTGSSKGIGLSIAKGLAENGAKVVISSRKQAAVDAVAKELKEAGMEAIGIECHIGDATQREQLIAKTMEAYGRIDILVNNAAINPFYGPLESADEDVFDKIMNVNVKAPWILSNLAQPHMKANGSGSIINIASVEGIHPGFRLGLYSMTKSAVIMLTKNQAKEWGRYGIRSNVVCPGLIKTKFSESLWSDEKLVEQYTSIVPLKRVAEPDEMAGIVMLLASDAGSYMTGGVYTADGGYLISG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6Z9C3</accession>
    <name>A0A5C6Z9C3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_20415</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000071">
        <property type="protein sequence ID" value="TXD86300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="95" mass="11024" checksum="0D4BB8B7B6C99D30" modified="2019-11-13" version="1">MILEIKSIDNFIAFKATSIKNGNFVLDQLENPFSIEKILTWQEFIQLYKTKAIELMSYRPTESSRGVETSRGGIETYIADDDIDYNKALEKMHKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-02-10" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZB82</accession>
    <name>A0A5C6ZB82_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">IS3 family transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000054">
        <property type="protein sequence ID" value="TXD86516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="124"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="305" mass="36310" checksum="907D69ABB687DA27" modified="2019-11-13" version="1">MSKRDRAKKEKPFKRKWFYQCFGISKQAFYKRLKTLENKQMNDQKLITMVKDYRNKVGQRTGGIKLHKELKDEFEESGIKIGRDKFYCFLRLHNLLVPKLKNYITTTNSKHNFRKYKNLVKDQVPTRPEQLWVCDITYIKTENGHNYLAIVTDAYSRQIMGYKLADHMRTSLCMEALDMAIKNRRYPNLKLILHSDRGLQYCNPKYTMFAESNGMILSMTEQYDPYENAVAERINRILKYEYGLKQTIKNTAIAQKITKQAVYIYNNLRTHFSLELRKPAEVHLNPNIKHRSYRKNKVNLPELSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBY5</accession>
    <name>A0A5C6ZBY5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SusC/RagA family TonB-linked outer membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000032">
        <property type="protein sequence ID" value="TXD86999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023996">
        <property type="entry name" value="TonB-dep_OMP_SusC/RagA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023997">
        <property type="entry name" value="TonB-dep_OMP_SusC/RagA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04056">
        <property type="entry name" value="OMP_RagA_SusC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04057">
        <property type="entry name" value="SusC_RagA_signa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Plug" evidence="1">
        <location>
            <begin position="223"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1100" mass="122359" checksum="C9C1EF5E6A0292A8" modified="2019-11-13" version="1">MQLKLTNTLFFQWKEISKFIVKTLLLLCCTTVFSLSSSAIFSQNEKVVIDSDKTMTIYEVLELIGKQTECTFIYQSDIFKDVPDIAIRKGVIKVMKLLQQCLPETEFKITTTKDSYITIIRKAPNPPRQVQIQIKGIITGVEGLPIPGVYISIDGSTNYTTSDFDGSFSLVESSNETLKFSLLGYQTQFVKLDGRTTINVTLIEDVTALDVVTLNAGYYSVKEKEATGNISKIEQKDIENQPVTNPLAAIQGRVAGVEITQTSGLPGAGFEIKIRGQNSIRANGNDPLYIIDGVPYASSTIGDVQTSLIIPGFGISPLNNINSDDIQSIEILKDADATAIYGSRGANGVVLITTKKGKFGATEFNIATTSGFGSIANRIDLLGTPEYLAMRREAYENEGIDPLPFNAYDINGTWDENRYTNWQKELIGKTARLENVQASFSSGNAQTRFLISGNYNKQTNVFPGDFSNRQMSVLSSINHKSKNEKLALQFSANFSSNNNDLPATSLVREALLLAPNAPTLYNEDGSLNWEDSTWNNPLRNLEGKYGSNSTNLISNLTIDYELFKDFKFITSLGYTQNNLSEIRTVPSTIFNPAFGLGPEISSAIHNDANRKSWIIEPQLHHNFKIFDTDVQTLVGLTFQEESSHQLSQIASGFTNNVLIENLAAASQLFVLADNPIEYRYNAFFGRVNLNHKQKYILNLTGRRDGSSRFGPNKQFANFGAVGAAWIFSNEDFIKETFPILSYGKIRGSYGTSGNDQIGNYEYLNTFSFGNTFYQNTIGLQPTRLFNPDFSWEENRKLEIAVELGLFKDVVLLSSSYYRNRSSNQLIGVPLPATTGFNSINANLDATVENRGLEFQLTSQNIKTEHFSWSSSVNLTIPKNELLSFPDLEGSSYANQLVIGQPLNIVKVYESQGVNPQTGLFEFTDFNNDGNISSPQDRQIVKDLNPEYYGGFENSLSYKNLSLNVLFQFTKQLGAHYLAGGNFIGAMSNQPVEVLDRWQNIGDVTDVQQFTTGLDPESALAFINYTQSDAGITDASYIRLKTVALSYQLPTIRQRVNCEVFLRGQNLLTLTKYNGLDPETRSRNTIPPLRFITLGTKFTFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC32</accession>
    <name>A0A5C6ZC32_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_17425</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000026">
        <property type="protein sequence ID" value="TXD87341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="130" mass="14967" checksum="7A802D2DD09A1EF9" modified="2019-11-13" version="1">MSDHVSLLENEAARFNVLGASEFDGRNKPFTTIFRGSKGYIIATYNNNGKLLKTTERYKDIKLPKYIVKSVLSQYPDCHLLKVVYTVDYDHQKEVEKTYKIQIMKDNKKRNLKISSGDNLNKAVTMSIDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCA8</accession>
    <name>A0A5C6ZCA8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19760</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000047">
        <property type="protein sequence ID" value="TXD86607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="184" mass="21065" checksum="486AE4023722BB4E" modified="2019-11-13" version="1">MKKILVYLLFVTLPLLSYSQSEPNLILDEKNGFKDLKIGDNYSKWSSDLTLTNTDNGIKYYDFIGSCCKKLFSSDLEKIGLGFKNNILDVIFLTTPTERDYSESWTSSEYRYLKGSFGEVLEEKAYESAPDDNSGDINSIWLGNKIQLILTFEYMGLKDFDGKYIKTSRCKVLISKRPDLKSGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCB5</accession>
    <name>A0A5C6ZCB5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Nicotinic acid mononucleotide adenyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_18380</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000031">
        <property type="protein sequence ID" value="TXD87046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="116" mass="13184" checksum="61D848F5430D8AE1" modified="2019-11-13" version="1">MLALILTLSMSFAFAQKDGKKVEITKNGDLTSATYFYADGSVEQQGTFNKEGQLHGVWISYDRVGNKTAIANYANNKKVGKWLFWTNNKLREVEYVDSRIASVNEWENKTEMAFSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCT9</accession>
    <name>A0A5C6ZCT9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Universal stress protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_18640</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal stress protein A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000033">
        <property type="protein sequence ID" value="TXD86948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="2">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="281" mass="32049" checksum="00BA518406554197" modified="2019-11-13" version="1">MKHILLPTDFSENSWNAISYAINLFKDETCTFHLLNNYMPMVYNVEYVLGYPAQFGLVDAMRNSSQVNLESLIKRIDKQFKNNPKHSFDTSLSLDNLVSGIQEFILKRPVNLIIMGTKGATGAKEVLFGTNTVDVFQKVKCPTLAIPSGFQFEPLKDLLFPTDLEVPFKNTELEIVADLVKKHKSKIHALHILTGTNVTLTQARNKLELESLFEELPFVYHEINNDSVTDGINSFQKDNKINVLIMCNNKHSFFENILFKSKVKQIGFHIQIPFLVIHSKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD30</accession>
    <name>A0A5C6ZD30_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF3109 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_18415</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000031">
        <property type="protein sequence ID" value="TXD87032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021458">
        <property type="entry name" value="DUF3109"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11307">
        <property type="entry name" value="DUF3109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="187" mass="21095" checksum="DB19C2013FB18303" modified="2019-11-13" version="1">MFQLGKAIVSEDIIEKDFVCNLSACKGACCINGDAGAPLELEETQILKDIYPKVKPFLRKQGIEAIEKQGTHITTEFGEHETPLIDGADCAYVIFGKNKTALCGIEEAYNQGEISWKKPVSCHLYPVRIKDYSEFSAVNYDRWEICDDACTLGKELQVPIYKFVKEGLIRKFGEDWYAELEKVANKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD42</accession>
    <name>A0A5C6ZD42_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carboxypeptidase-like regulatory domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_16225</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023095667" evidence="1">
        <location>
            <begin position="24"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="475" mass="55079" checksum="1A57E2303F4CC03D" modified="2019-11-13" version="1">MKPTFIKKTLLVLILLSTALSFSQTEVKNKIVDFSSLMPIESASIYVKETTIGTVSNSDGKFILQVPNEFATDTLVISSIGYKSYKVPVDEFDNSFEIYLEEDVASLDEILLVAETRPKTGNDIVLKAIEKLVVNMPDSAYLQKGFLRHKERNKLEFKWLIESAITVYDSGYGSKSAEELKINVDQMRKSYDLRDVDSIFSYVAYTNQTSARSRIKPKDVNRRNLSKAQLVKAIKWNDERVNGLQNLFEGKLNLVRNANDPKALFGEDMLKKHQFELDTILVDNDRKLYKIQIEGGEQFVGLDTEGIFNEGYTPKGWLYIYYDNYAIKKVEYELEAASDAQKVRSKRLFDTTVNHKLVITYIEYDDKMYPNYVYYETPKLVNVGIKSTQKISKAEEARYNKEERYYYTVQEILFSEIVLDKDKLAEARQQKWDDDIFSAKPYNKSFWENYNILLESEEDEQLISDLSKRASLFKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD50</accession>
    <name>A0A5C6ZD50_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_15875</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="94" mass="11039" checksum="A46AD184032558BD" modified="2019-11-13" version="1">MNEKFKDLPVEEDTQIIVSVEAKIEDYDVVYQKWHWDGITAESIIFFNDDIAELTEDQIKNEVALCTAMVKENSQMTFKKGEKYTFVNFNFTTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD53</accession>
    <name>A0A5C6ZD53_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Large-conductance mechanosensitive channel</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9 10" type="primary">mscL</name>
        <name evidence="10" type="ORF">ESY86_18235</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homopentamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the MscL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000030">
        <property type="protein sequence ID" value="TXD87072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00115">
        <property type="entry name" value="MscL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001185">
        <property type="entry name" value="MS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037673">
        <property type="entry name" value="MSC/AndL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036019">
        <property type="entry name" value="MscL_channel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30266">
        <property type="entry name" value="PTHR30266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01741">
        <property type="entry name" value="MscL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01264">
        <property type="entry name" value="MECHCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81330">
        <property type="entry name" value="SSF81330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00220">
        <property type="entry name" value="mscL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0407">Ion channel</keyword>
    <keyword evidence="6 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD87072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="134" mass="14413" checksum="C6BD730A437564B5" modified="2019-11-13" version="1">MFKEFKNFIMTGNVIDLAVAVILASAVSMVVNGFVSDIMMPIVGNFAGNVDFADLKYVLSPANVGADGDITKPENAIMYGKWVNSIINLIIVGLVLFTIVKAYNKTKKPAAPAAPAGPTELDILKEIRDELKKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD67</accession>
    <name>A0A5C6ZD67_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type I restriction enzyme HsdR N-terminal domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029464">
        <property type="entry name" value="HSDR_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13588">
        <property type="entry name" value="HSDR_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HSDR_N_2" evidence="1">
        <location>
            <begin position="36"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="149" mass="17907" checksum="70EDFC94DE94DEA8" modified="2019-11-13" version="1">MLQDLNFPKFTFRFKNSENKVSIFDEIRKKFIILQPEEWVRQHTVRFLMEHKNYPKSLINVEKELKLNGLSKRYDVVVFNPDGSLHLIVECKAPKIKINQSTFDQIARYNLELNATYLMVTNGINHYYCQMDFENEKYVFLKDIPEYES</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDB5</accession>
    <name>A0A5C6ZDB5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_16900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000024">
        <property type="protein sequence ID" value="TXD87457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03220">
        <property type="entry name" value="ABC_KpsT_Wzt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10147">
        <property type="entry name" value="Wzt_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015860">
        <property type="entry name" value="ABC_transpr_TagH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029439">
        <property type="entry name" value="Wzt_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14524">
        <property type="entry name" value="Wzt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="48"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="85"/>
            <end position="92"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD87457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="431" mass="48152" checksum="EB1E04FACE9D3F3B" modified="2019-11-13" version="1">MSNNNKDIILVAENISKQYRLGVVGTGTLSHDLNRWWHRVRGKEDPFLKVGEVNDRSTSGSSDYAWALRDINFEVQRGEVLGIIGKNGAGKSTLLKILSRVTSPTTGEIKTKGRIASLLEVGTGFHPELTGRENIYLNGAILGMSKAEIKAKEEEIIEFSGCQRYVDTPVKRYSSGMRVRLAFAVAAHLEPDILVIDEVLAVGDAEFQKKAIGKMQDISKGEGRTVLFVSHNMAAVKSLCTRAIVLENGVSVFEGDTDAAVDFYLHNEKLLIKSKLLELTDRIGSGKVLFSKFEILNIENKILSAAMSGEYIKLRVHFHAHEVVQLKNCRISISVKKDERDYIVLSSELVLNYNLNLTNSEKVDFILEKFPLSKGLYKIELFLESEREIIDWIKNASDLHVENGDFYGIGKSYPKGWEGKTVLVENKIEVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDC2</accession>
    <name>A0A5C6ZDC2_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphoribosylformylglycinamidine cyclo-ligase</fullName>
            <ecNumber evidence="3">6.3.3.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">AIR synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Phosphoribosyl-aminoimidazole synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">ESY86_16635</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>2-formamido-N(1)-(5-O-phospho-beta-D-ribosyl)acetamidine + ATP = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole + ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:23032"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:137981"/>
            <dbReference type="ChEBI" id="CHEBI:147287"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.3.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AIR synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.3.1" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000023">
        <property type="protein sequence ID" value="TXD87520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00129"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004641">
        <property type="term" value="F:phosphoribosylformylglycinamidine cyclo-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.650.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010918">
        <property type="entry name" value="PurM-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036676">
        <property type="entry name" value="PurM-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036921">
        <property type="entry name" value="PurM-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004733">
        <property type="entry name" value="PurM_cligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10520">
        <property type="entry name" value="PTHR10520"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02769">
        <property type="entry name" value="AIRS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55326">
        <property type="entry name" value="SSF55326"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56042">
        <property type="entry name" value="SSF56042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AIRS_C" evidence="10">
        <location>
            <begin position="183"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD87520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="392" mass="42982" checksum="F14B64A75E1C4B2A" modified="2019-11-13" version="1">MSEDTSKRYAQRGVSASKEDVHNAIKNIDKGLFPKAFCKIVPDYLTNDEDYCLIMHADGAGTKSSLAYMYWKETGDLSVWKGIAQDALIMNIDDLICVGATSDILLSSTIGRNKNLIPGEVISALINGTEALIADLKNFGISIHSTGGETADVGDLVRTIIVDSTVTARIKRSHVIDNANIKAGDVIVGLESFGQATYETGYNGGMGSNGLTSARHDVFGHYLAEKYPESYDASVPKELVYSGHMKLTDAVEGAPIDAGKLVLSPTRTYAPIIKKILDVFSSEDIHGMIHCSGGAQTKILHFVEQLHIIKDNMFEIPPLFKLIQEQSKTSWKEMYQVFNCGHRMELYVNPEVAEQIIGISKSFNVNAQIVGRVEASEEKKLSIKSQFGVFEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDP9</accession>
    <name>A0A5C6ZDP9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glycoside hydrolase family 97 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_16080</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000021">
        <property type="protein sequence ID" value="TXD87671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029483">
        <property type="entry name" value="GH97_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019563">
        <property type="entry name" value="GH97_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029486">
        <property type="entry name" value="GH97_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14509">
        <property type="entry name" value="GH97_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14508">
        <property type="entry name" value="GH97_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10566">
        <property type="entry name" value="Glyco_hydro_97"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022943150" evidence="2">
        <location>
            <begin position="22"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="domain" description="GH97_N" evidence="4">
        <location>
            <begin position="31"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_97" evidence="3">
        <location>
            <begin position="303"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="domain" description="GH97_C" evidence="5">
        <location>
            <begin position="591"/>
            <end position="692"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF14509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD87671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="696" mass="78876" checksum="F3D53FF3585F35DA" modified="2019-11-13" version="1">MKYIIKFFLPILILILLNACASEGKKFTSEVTSPDKNIKVSFHLSAENQPFYVVNYKTEKVIDSSKMGFELKDAAPLSGDFRIVATDTASVNETWQPVWGEDAEVKNEYNELKLQLEETSALKRKINIIFKVYDDGIGFRYEFPKQENLNEVVITDENTEFNLTGNHKVWWIPGDWDIYEYLYQTTKFSEIDALKLYEPGTHLGQTYMPENAVNTPVTMKTEAGLYLSFHEADLTDYAGMTLAVDTTNHKMKSELVGNAENIKVKRQTPFETPWRTIQIAEKPGQLIESKLIVNLNDPNVVEDMSFFKPTKYTGIWWDMHIGTGNWDYAGANHAANTTYAKELIDFSAKHNINAMLVEGWNIGWEQWWDKKAKQVDFDFVTPYPDYDLQEVVRYGKSKGVALIMHHETSADVTGYEAQIDTAFALMKDLKIHAVKTGYVGSVIPEGEYHHGQFMVNHYQKVLEKGIENQVAINAHEPIKATGKRRTYPVAISREGVRGQEYNAWSDDGGNPPEHLTIVPFTRMLGGPVDYTPGIFNTSLKPYKENNQINTTLAHQLALYVVVYSPVQMVPDLIKNYEGHPAFQFIEDVGIDWQQSKVLDAEIGDFIVMARQEKQTGHWFLGAITDEQARTVTINFDFLEAGKNYTATIYKDAADAHYKTNPEAYEISSEDISNNSKLELMLAAGGGVAIAIKESNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDS4</accession>
    <name>A0A5C6ZDS4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PorT family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_18680</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000033">
        <property type="protein sequence ID" value="TXD86954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025665">
        <property type="entry name" value="OMP_b-brl_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13568">
        <property type="entry name" value="OMP_b-brl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023092356" evidence="1">
        <location>
            <begin position="21"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="OMP_b-brl_2" evidence="2">
        <location>
            <begin position="20"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="196" mass="21260" checksum="F09BF29A4E65A832" modified="2019-11-13" version="1">MKKSVASTLLLVLISLSVNAQEGSSFGLKGGLNYNANGDYFESVSSNAKQPDRNIGYHIGVFGKIGNDLYFRPELVYTSTKSDYDSDDFSMQKIDAPLLVGVKIIGPVSVFAGPSLQYILDTEFSGINIDNVKEDFSVGLNFGISANLGRLGVDLRYERGFSDNEATFINNNIGDGVVSRIDTRPEQLILSLSLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE11</accession>
    <name>A0A5C6ZE11_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-dependent zinc metalloprotease FtsH</fullName>
            <ecNumber evidence="5">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">hflB</name>
        <name evidence="5" type="synonym">ftsH</name>
        <name evidence="9" type="ORF">ESY86_15100</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
            <orientation evidence="5">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">In the C-terminal section; belongs to the peptidase M41 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">In the central section; belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="5"/>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01458">
        <property type="entry name" value="FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005936">
        <property type="entry name" value="FtsH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000642">
        <property type="entry name" value="Peptidase_M41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037219">
        <property type="entry name" value="Peptidase_M41-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01434">
        <property type="entry name" value="Peptidase_M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140990">
        <property type="entry name" value="SSF140990"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01241">
        <property type="entry name" value="FtsH_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 5 9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 5 9" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="8">
        <location>
            <begin position="228"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="642"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="460"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="236"/>
            <end position="243"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="459"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="463"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="534"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD87995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="666" mass="73757" checksum="AD2383B854A473C3" modified="2019-11-13" version="1">MAKDNNNLNKKPKFSPYWIYGFIIAAFLGFQLISGGLSGSDVKQINPNQFFEFMKDGDVAKVNIINNREARVYLVKEALAKEVHKGTKPNNILPSVSPQANYSFEFGDLKLFQEEINKIKAESNLTVPVSFKTEENVWGNFIFSLLPFVLIIGVWIFIMRRMSSGGGGGAGGQLFNIGKSKAKLFDEKTDVKTSFKDVAGLEGAKEEVQEIVDFLKFPEKYTSLGGKIPKGALLVGQPGTGKTLLAKAVAGEAKVPFFSLSGSDFVEMFVGVGASRVRDLFKQAKEKSPSIIFIDEIDAIGRARGKSNMSGSNDERENTLNQLLTEMDGFGTNTNVIVLAATNRADVLDKALMRAGRFDRQIFVDLPDVRERKEIFEVHLRPIKQSEKLDIDFLAKQTPGFSGADIANVCNEAALIAARNGKKAVDKQDFLDAVDRIVGGLEKKNKIITKDEKKAIAYHEAGHATVSWMLEHAAPLVKVTIVPRGQSLGAAWYLPEERLIVRPEQMLDEMCAALGGRAAEKVIFDKISTGALSDLEKVTKQARAMVTIYGLSEKVGNLTYYDSSGQSEYNFSKPYSEKTSELIDNEISDIIETQYRRAIALLEDNKDKLTQLAEVLLEKEVIFKDNLEKIFGKRPFEKRELITPEDTPASTGAEVKGEEIKIEDDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE34</accession>
    <name>A0A5C6ZE34_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Phosphoenolpyruvate carboxykinase (ATP)</fullName>
            <shortName evidence="8">PCK</shortName>
            <shortName evidence="8">PEP carboxykinase</shortName>
            <shortName evidence="8">PEPCK</shortName>
            <ecNumber evidence="4 8">4.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 9" type="primary">pckA</name>
        <name evidence="9" type="ORF">ESY86_13940</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + oxaloacetate = ADP + CO2 + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:18617"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.1.1.49"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="8">Binds 1 Mn(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.49" evidence="4 8"/>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004612">
        <property type="term" value="F:phosphoenolpyruvate carboxykinase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00484">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.449.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00453">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001272">
        <property type="entry name" value="PEP_carboxykinase_ATP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013035">
        <property type="entry name" value="PEP_carboxykinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008210">
        <property type="entry name" value="PEP_carboxykinase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30031">
        <property type="entry name" value="PTHR30031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01293">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006294">
        <property type="entry name" value="PEP_crbxkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68923">
        <property type="entry name" value="SSF68923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00224">
        <property type="entry name" value="pckA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="8" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="9" id="KW-0418">Kinase</keyword>
    <keyword evidence="7 8 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="8">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="201"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="221"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="237"/>
            <end position="245"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="287"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="323"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="448"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD88196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="538" mass="60100" checksum="9325631BFC6EBE99" modified="2019-11-13" version="1">MVDHTQTTKTIALEHYGIKNAKVRYQLPPDELQKITVDKGQGVETASGTLAVNTGEFTGRSPQDRFIVKDDITKDRVWWSNINIPFESDKFQKLYDKVADYLSEKEVFVRDSFACADENYKLKIRVITEHPWSNMFAYNMFLRPTEAELENFTPEWTVVNAPGFMADPEVDGTRQHNFAILDFTRKIALIGGTGYTGEIKKGIFSALNFILPVFKETMPMHCSANVGKDGDTAIFFGLSGTGKTTLSTDPNRSLIGDDEHGWTKENTVFNFEGGCYAKVINLSQEHEPEIYGAIKKGAILENVILNGKGEVDFEDTSITQNTRVSYPIYHIDNIRKPSIGKNPKNIFFLTADAFGVLPPISKLTPSQAAYHFISGYTAKVAGTEAGVVEPVPSFSACFGAPFMPLHPAKYAEMLSEKMKASGVNVWLVNTGWTGGPYGVGTRMKLKYTRAMINAVLNGELGLYDYDHYHIHSVFGVAQPRTCPGVPDEVLSPRTTWNDDENYYKTAFKLTNAFRENFKKFEADASEATRRGGPQRYAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEF9</accession>
    <name>A0A5C6ZEF9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5 7">50S ribosomal protein L16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">rplP</name>
        <name evidence="9" type="ORF">ESY86_14865</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 7">Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 7">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uL16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01433">
        <property type="entry name" value="Ribosomal_L16_L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01342">
        <property type="entry name" value="Ribosomal_L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016180">
        <property type="entry name" value="Ribosomal_L10e/L16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036920">
        <property type="entry name" value="Ribosomal_L10e/L16_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000114">
        <property type="entry name" value="Ribosomal_L16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020798">
        <property type="entry name" value="Ribosomal_L16_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12220">
        <property type="entry name" value="PTHR12220"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00252">
        <property type="entry name" value="Ribosomal_L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00060">
        <property type="entry name" value="RIBOSOMALL16"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54686">
        <property type="entry name" value="SSF54686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01164">
        <property type="entry name" value="rplP_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00586">
        <property type="entry name" value="RIBOSOMAL_L16_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00701">
        <property type="entry name" value="RIBOSOMAL_L16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L16" evidence="8">
        <location>
            <begin position="4"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD87948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="139" mass="15790" checksum="D4C166DFD9A5BD5F" modified="2019-11-13" version="1">MLQPKRTKFRKVQKGRMKGNAGRGHRLSYGMFGIKSMDTNFLTSRQIEAARIAATRYMKREGQLWIKVFPDKPITKKPLEVRMGKGKGAVEYWVAVVKPGRILFEIGGVPLEVAKEALRLAAQKLPVKTKFLIARDYEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEG8</accession>
    <name>A0A5C6ZEG8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">30S ribosomal protein S5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rpsE</name>
        <name evidence="11" type="ORF">ESY86_14915</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.</text>
    </comment>
    <comment type="function">
        <text evidence="7">With S4 and S12 plays an important role in translational accuracy.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.</text>
    </comment>
    <comment type="domain">
        <text evidence="7">The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 9">Belongs to the universal ribosomal protein uS5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01307_B">
        <property type="entry name" value="Ribosomal_S5_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000851">
        <property type="entry name" value="Ribosomal_S5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005712">
        <property type="entry name" value="Ribosomal_S5_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005324">
        <property type="entry name" value="Ribosomal_S5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013810">
        <property type="entry name" value="Ribosomal_S5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018192">
        <property type="entry name" value="Ribosomal_S5_N_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13718">
        <property type="entry name" value="PTHR13718"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00333">
        <property type="entry name" value="Ribosomal_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03719">
        <property type="entry name" value="Ribosomal_S5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01021">
        <property type="entry name" value="rpsE_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00585">
        <property type="entry name" value="RIBOSOMAL_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50881">
        <property type="entry name" value="S5_DSRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 7 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="S5 DRBM" evidence="10">
        <location>
            <begin position="18"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD87958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="174" mass="18090" checksum="4D7288E8335C8386" modified="2019-11-13" version="1">MYHKYKNAELVKPSGIDLKDRLIGVQRVTKVTKGGRAFGFSAIVVVGDEAGVVGQGLGKSKDVATAIAKAVEDAKKNLVRIPIIKGTLPHEQKGKYGGARVNIIPAAPGTGVIAGGAVRTVLESVGVHDVLSKSQGSSNPHNVVKATFDALLQLRSAASVAKERGISLDKVFNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEH2</accession>
    <name>A0A5C6ZEH2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF481 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_14980</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007433">
        <property type="entry name" value="DUF481"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04338">
        <property type="entry name" value="DUF481"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="251" mass="29267" checksum="9D7D2E6EAACF15E5" modified="2019-11-13" version="1">MRFFLILILLLISMSCFSQVINIETLRKASDSAKWSGSVGLDVSLIKNTNSIFRIANKAHVQYNDQFNSWLFVNDLNFEKVEGNSLVNKGTQHLRYNRRLNQWLKWEAFAQSQYDAISEIDFRGLLGMGPRFKLSSDEDYRFYLGTLLMYEYEQATNVVSNRIEKDIRASAYLSFSLYPTESISIISTSYYQPKLKVFKDYRFSSNTAILFKIYEDLAFKTNFNFIYDAFPVSTAVPSTQYEWTNGILYSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF46</accession>
    <name>A0A5C6ZF46_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022675444" evidence="1">
        <location>
            <begin position="22"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="240" mass="27315" checksum="2D1CEDE2ECD873F2" modified="2019-11-13" version="1">MKKILILFVVVMYLAPQNLKAQNDGAAVATVAGGLLAIGAGIAAIEQMKEQAELTATEWFLTNHPEYNKFSLKTLDFDGKKLKDMSSTSVITFKIREFDIKGNEPELGKKLVLFGFTSYGWINEYGIDFSKVEWFLIDSNEWMNMMTAYTKVASSEKNEGTIRGALKDGKVVNKGVKVKNREDIDFYKIEGDMYLVTDYSPEMKFIYNERSLGIYLKETMNLIQIGRGNLINIHEFFFDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF48</accession>
    <name>A0A5C6ZF48_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_16995</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000025">
        <property type="protein sequence ID" value="TXD87368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="83" mass="10043" checksum="8AAF39F862AF3C95" modified="2019-11-13" version="1">MDRDDNSREKEFLGNELARKTTESNDLQNRYTQREADVELRQIQLRKDFELLASKLVMLYLTRTYKRQTTPKFYLEGCFTIRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF54</accession>
    <name>A0A5C6ZF54_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DNA alkylation repair protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_15480</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014825">
        <property type="entry name" value="DNA_alkylation"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08713">
        <property type="entry name" value="DNA_alkylation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="229" mass="26609" checksum="A20C50ED031DCD51" modified="2019-11-13" version="1">MTAKAFIETLKIIGQDYSGEIPKRELFSLAKAYQQIPVSEVVKLLKDENVNHRLGAVSILDWKARHKKTSKTEREKIYSAYIDNHKWIDNWGLVDRSAPYVVGGYLHDKDKKALYDLAKSKNPMERRTAIVSTYYFIRKNEIEDTFEIAEILVYDTDESVQKAVGSWIREAGKQNEEKLKKFLDKHASDMPRITLRYAIEKFDKKSRAYYLNLKKQAEKPAGNKDVNNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF55</accession>
    <name>A0A5C6ZF55_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4296 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_13965</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025381">
        <property type="entry name" value="DUF4296"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14129">
        <property type="entry name" value="DUF4296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4296" evidence="1">
        <location>
            <begin position="25"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="151" mass="17457" checksum="002408F4FB3FECB3" modified="2019-11-13" version="1">MKYLMLLLILGLGMGCAKDIRPKKPDNLIAKEQMVNVLYDIAILNAAKGALKNVLEEEGIYPQKYLFEKHKIDSLQFAQSNDYYSYDVSTYEEIIDQVNAKIEAQRKIYEDKVDKEAKRQQRKKDSIRKLSDRVNQALIKPDVKAKTDTTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFC9</accession>
    <name>A0A5C6ZFC9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">O-succinylbenzoate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12105</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009063">
        <property type="term" value="P:cellular amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029065">
        <property type="entry name" value="Enolase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018110">
        <property type="entry name" value="Mandel_Rmase/mucon_lact_enz_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013342">
        <property type="entry name" value="Mandelate_racemase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13378">
        <property type="entry name" value="MR_MLE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00922">
        <property type="entry name" value="MR_MLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="SSF51604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="SSF54826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00909">
        <property type="entry name" value="MR_MLE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MR_MLE" evidence="1">
        <location>
            <begin position="128"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="349" mass="39308" checksum="C05003B21E8D88A4" modified="2019-11-13" version="1">MTATYHKHLLNFKQASGTSRGILKTKDTWFLIICRDGKKGIGECGMFKGLSVDDRPDFESKLQWACDNIHLGLENLVLRLQEFPSIQCGLEMAFNSLESKDVFDLFPSAFTKGIDHININGLIWMGSETFMKQQIKEKLDSGFRCIKMKIGAIDFASEIGLLKSIREEFSAADIELRVDANGAFSAENALEKLKRLSHFDLHSIEQPIQQGQTEAMAGLCEQTPLPIALDEELIGVFSEEKKQELLQIINPQYIILKPTLIGGFTGSQNWIDLAEKQQIGWWVTSALESNIGLNAIAQWTYTLQNQMPQGLGTGSLFSNNFDSPLKVKNANLHYDQNKHWDLKNLGFQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFS1</accession>
    <name>A0A5C6ZFS1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">SCO family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_14515</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SCO1/2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02968">
        <property type="entry name" value="SCO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003782">
        <property type="entry name" value="SCO1/SenC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12151">
        <property type="entry name" value="PTHR12151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02630">
        <property type="entry name" value="SCO1-SenC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="64"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD88095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="250" mass="28258" checksum="A2A8BDBD0108637A" modified="2019-11-13" version="1">MSSKKTNYSYIGIAFVLLVFGIIFIPKIVDRIKNGDISRDESRSSAISVNAKDELSDLMFLEINGSPKKVPPFEFVNQDGDTITNKDYEGMVYLVEFFFTTCPSICPKMNRNLVQIQNTFTGFENFGIAAFTINPEYDTPEVLKAYAKNYGITNPNWNLMTGNKEEIYALANIGFNIYAAENPEVEGGFEHSGSFALIDKNGFMRSRQDDFGNPKIFYKGIISEEEQQDEDGETEEISMLKEDIAKLLKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFV1</accession>
    <name>A0A5C6ZFV1_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fused isobutyryl-CoA mutase</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="5">Isobutyryl-CoA mutase</fullName>
                <shortName evidence="5">ICM</shortName>
                <ecNumber evidence="5">5.4.99.13</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="5">P-loop GTPase</fullName>
                <ecNumber evidence="5">3.6.5.-</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="5">G-protein chaperone</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="5" type="primary">icmF</name>
        <name evidence="8" type="ORF">ESY86_16590</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>2-methylpropanoyl-CoA = butanoyl-CoA</text>
            <dbReference type="Rhea" id="RHEA:13141"/>
            <dbReference type="ChEBI" id="CHEBI:57338"/>
            <dbReference type="ChEBI" id="CHEBI:57371"/>
            <dbReference type="EC" id="5.4.99.13"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>GTP + H2O = GDP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="domain">
        <text evidence="5">Is composed of four functional domains: the N-terminal 5'-deoxyadenosylcobalamin binding region that is homologous to the small subunit of ICM (IcmB), a middle P-loop GTPase domain (MeaI) that likely acts as a chaperone for ICM, a structured linker region involved in dimer formation, and a C-terminal part that is homologous to the large substrate-binding subunit of ICM (IcmA).</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the IcmF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.13" evidence="5"/>
    <dbReference type="EC" id="3.6.5.-" evidence="5"/>
    <dbReference type="EMBL" id="VORO01000023">
        <property type="protein sequence ID" value="TXD87511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047727">
        <property type="term" value="F:isobutyryl-CoA mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034784">
        <property type="term" value="F:pivalyl-CoA mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006637">
        <property type="term" value="P:acyl-CoA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02050">
        <property type="entry name" value="IcmF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016176">
        <property type="entry name" value="Cbl-dep_enz_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006158">
        <property type="entry name" value="Cobalamin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036724">
        <property type="entry name" value="Cobalamin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033669">
        <property type="entry name" value="IcmF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006099">
        <property type="entry name" value="MeMalonylCoA_mutase_a/b_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02310">
        <property type="entry name" value="B12-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01642">
        <property type="entry name" value="MM_CoA_mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51703">
        <property type="entry name" value="SSF51703"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52242">
        <property type="entry name" value="SSF52242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51332">
        <property type="entry name" value="B12_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2 5" id="KW-0846">Cobalamin</keyword>
    <keyword evidence="4 5" id="KW-0170">Cobalt</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="B12-binding" evidence="7">
        <location>
            <begin position="12"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="1074"/>
            <end position="1105"/>
        </location>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="25"/>
        </location>
        <ligand>
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </ligand>
        <ligandPart>
            <name>Co</name>
            <dbReference type="ChEBI" id="CHEBI:27638"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="211"/>
            <end position="216"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="240"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="253"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="301"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="302"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="348"/>
            <end position="351"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="597"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="632"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="782"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="826"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="875"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="910"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="915"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="1027"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="1146"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD87511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1147" mass="128306" checksum="AFE0BC0AAC3467E1" modified="2019-11-13" version="1">MKQATPYTPKHNVRIVTAAALFDGHDASINIMRRIIQSTGVEVIHLGHDRSVEEVVNTAIQEDVNAICITSYQGGHNEYFRYMHDLLKEKGAGHIKIFGGGGGVILPSEIKELMDYGIDRIYAPDDGREMGLQGMINDLVEQSDFESPALSLPKNKDVRTSVKDKDVPTIARLISFAESQHDKFKTHFSSIEKLPKTKDETVVLGITGTGGSGKSSLVDELVRRFLIDFPEKTIGIVSVDPSKRKTGGALLGDRIRMNAINSPRVYMRSLATRQSNLALSKYVNEAVEVLKAAEYDLIILETSGIGQSDTEIVEHSDVALYVMTPEFGAATQLEKIDMLDFADLVSINKFDKRGSLDALRDVKKQYMRNHQLWDTPQDDLPIFGTIASQFNDPGMNKLYRAVMDKLVEKTNTDLKSTFHVSEEMSEKIFVIPPARTRYLSEIAENNRAYDKTASEQQEVAQTLYGIFKTLASVSGQTPTMDKAGIDSDSLAATSEDSKPLVKLLVSEFDRVKLNLDPYNWEIITSWDEKVNRYKNPVYTFKVRDREIKIDTQTESLSHSKIPKVALPKYQAWGDILKWCLQENVPGEFPYTSGLYPFKRTGEDPARMFAGEGGPERTNRRFHYVSMGLPAKRLSTAFDSVTLYGNDPGLRPDIYGKIGNAGVSICCLDDAKKLYSGFDLASAMTSVSMTINGPAPMLLGFFMNAAIDQQCEIYIKENGLEKEIDAKITKIYKTKGVDRPKYNGELPEGNDGLGLMLLGITGDLVLPQAVYEDIKMKTIAQVRGTVQADILKEDQAQNTCIFSTEFALRLMGDVQEYFIENKVRNFYSVSISGYHIAEAGANPISQLAFTLSNGFTYVEYYLSRGMDINDFGPNLSFFFSNGIDPEYAVIGRVARKIWSKALKNKYGANSRAQMLKYHIQTSGRSLHAQEIDFNDIRTTLQALYAIYDNCNSLHTNAYDEAITTPTEESVRRAMAIQLIINKELGLAKNENPIQGSFIIEELTDLVEEAVLLEFDRITERGGVLGAMETMYQRSKIQEESLYYETLKHNGEFPIIGVNTFLSSKGSPTVVPAEVIRATEEEKQMQIQTLENLHKAFEDQIEATLDKVQQAAIHNENIFEVLMEATKVCSLGQITNALFEVGGQYRRNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG17</accession>
    <name>A0A5C6ZG17_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Putative sulfate exporter family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_10770</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0324 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD89013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018383">
        <property type="entry name" value="UPF0324_pro"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30106">
        <property type="entry name" value="PTHR30106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03601">
        <property type="entry name" value="Cons_hypoth698"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="61"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="113"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="143"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="212"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="237"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="268"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="293"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD89013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="317" mass="33341" checksum="F747F78A42CFD91D" modified="2019-11-13" version="1">MSSFNAAKPNKLSAKFIFFALALLCLLPFVSAPLALGLGIIMAQFLKNPYPEKSSKIVSWLLKVAVIGLGFGMSVDSALSAGREGFLFTVSSILLTLSLGLLIGKLLGIDKKITQLISVGTAICGGSAIAAIAPIIKADAKQISVAVGIVFVLNAVALFAFPPIGHLLEMSQHQFGLWSAIAIHDTSSVVGAADVYGHEALQTATTVKLARALWILPLSLVFTMFGSGNLKNVKIPYFIGLFILAIIANTYLPGVDGVSAYIVETSKMALTLVLFLIGSTLSFSTIKTVGFKPLALAIGIWMFISILALIVILNTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGB4</accession>
    <name>A0A5C6ZGB4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Peptidase M19</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_10870</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070573">
        <property type="term" value="F:metallodipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008257">
        <property type="entry name" value="Pept_M19"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01244">
        <property type="entry name" value="Peptidase_M19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="485" mass="55017" checksum="8B16EA5BF63C40B8" modified="2019-11-13" version="1">MITERNNYVDFHCHSAIKPYGKSFNYKKTGVNNSNRGRSSSIWRYDPPSLGDKLLNYVINLTKFSQANFTSLSKGGVSVVCESLYPIEKYFFENKIKSELIKDITANFATGLGRNRVDMVQAMTNYFEDLEREYDFYKQLNNVIVSLPEGRFKYRIVRSYAEIDAVMEAAKKETNKITTICVIMSIEGLHVLNDSIDQPPSETSFLKNLQAIKNWEAPPFFVTVAHHFWNHICGHAESFTKLVKSKVDQSEGLNLGFTAMGIKIVHALLSTENGKRILIDVKHMSVASRTEYYALLDQNADYKNIPIIASHAAANGMRSFEDTTQSGSKVANQLKAVDINIYNAELIRIAKSKGILGLQLDERRVASEATLKATRQSLSRSKIMHYRSELLWNQIQHIAEVLDHEQLFAWDCIAIGSDFDGIIDPLNSFWTAEELPFLADFLERHAYNYLKGAKFKVEANAIQADEVIARVMSKNGMAFLKTHFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGE1</accession>
    <name>A0A5C6ZGE1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Heme-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_11660</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005624">
        <property type="entry name" value="PduO/GlcC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038084">
        <property type="entry name" value="PduO/GlcC-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03928">
        <property type="entry name" value="Haem_degrading"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143744">
        <property type="entry name" value="SSF143744"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="127" mass="13381" checksum="5A35F0F79A1D5A03" modified="2019-11-13" version="1">MAAKITQAAFDEAERDGLFISVTIVDKSGPTLAVLRHHNAGVHTLRAIYKKAFTACSQKRDTATIAKGDKEGNIPEDIRFLDENILIMDGGIPIVIDGQVVGGIDVGGAHGSEDVRAAQAGLTALEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGH5</accession>
    <name>A0A5C6ZGH5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Universal stress protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_11270</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal stress protein A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="2">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="274" mass="31127" checksum="D95365C9ABBDF5DB" modified="2019-11-13" version="1">MKRILLLTDFSDNALEAMHYALHFFKAQACEFYVLHVHKVKSYISDDLMAAPNASIHDSITIKPKEKLEALINTFRSDFNNSQHTFEALIDFDVFEDAVNQVVSKHEIDYVVMGTNGITGANEVLFGSNTLNVIRKVDCTTIIIPEAYKFKPLNSFLLSLQPEDSLNDAPFKEVMDFIKTHKLQLHVLRMGIGGEVSEIARFDKQKLAIINCKYELAEDIPIAEAVSAYLNTHDIDMMAATIHKQSFLERLFNKSQTESINENLQIPLLVLHDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGJ0</accession>
    <name>A0A5C6ZGJ0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_11380</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0675">Receptor</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="889" mass="102777" checksum="EB0CC1C4C42EC11C" modified="2019-11-13" version="1">MNGKNKWLSLIFIFIIPLHFFSQTKISGLVIDENENIISSANVILKDSTNDAILSYTYSNDNGHFDIQTDTFGKLHLLITSLGFYKKLIPIELTKYQKELKIKVILKEKTLDLDEIIIQAENPINIKKDTISFKTKFFVNGSEQTVEDLLKKIPGLQVDDNGVIKIGNQEIEKLMIDGDDLFENGYRILSKNMPAYPIEEVEVLKNYSNNPLLKGIEESNKVALNLKLDEKSKRIWFGNVETGIGNDSFYELRSNLMNFGKKNKYYFFTNLNSIGYDATGDIENLIRPSRRNEPASIGDNQSVHSLLNLSPGHLNFKQNRTNFNNAELVSLNAIFNPTEKLKIKTLGFFNWDETDFFRNSINIVDVNGTNFTNIEDYQLQNKNSVAFGKLDITYNISKTKMLEATTKYNNGTFNDGSNLVFNGNSTIENLQHQNTLFDQKINYTNKFKDKKVFLVTGRFIDEKTPQNYAINQFFYQDLFPSTTNVNNVNQRSINQMQYVGVNAHLLDRKDNGNLLELQLGNEFRKDKLQTTFSLLENNTVLEQPNDYQNQTTYQVNDLYLKSKYRLKIDDFGIVGKLNVDQLFNRLDNNGNASSQNPFFINPSLGFDLEINDNNKITSSYSYNTTNATVLDVFNDFVLTGFRSFSKGAGNFNQLDASSFVFNYQLGNWSDRFFANTFILYSKNHDFFSTNTALNQNFNLAEKILIKDREFISIDSKLDYYFKFISSNLKLDLTYTKSEFKNIVNNSDLRRVTSYNYNYGLELRSGFSGVFNYHIGTKWNTIEIETTINNSFTNNVSFLDLSLVFNKKIDFQLQSERYYFGNLQTDNTYYFLDFDARYKVIENKLTLGLTGKNLFNTKRFRNFSISDIGSSTTEYRLLPRFVLLKLEYRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGS0</accession>
    <name>A0A5C6ZGS0_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cyanophycin synthetase</fullName>
            <ecNumber evidence="7">6.3.2.29</ecNumber>
            <ecNumber evidence="6">6.3.2.30</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Cyanophycin synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">cphA</name>
        <name evidence="12" type="ORF">ESY86_14285</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the ATP-dependent polymerization of arginine and aspartate to multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[L-4-(L-arginin-2-N-yl)aspartate](n) + ATP + L-aspartate = [L-4-(L-arginin-2-N-yl)aspartate](n)-L-aspartate + ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13277"/>
            <dbReference type="Rhea" id="RHEA-COMP:13728"/>
            <dbReference type="Rhea" id="RHEA-COMP:13733"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:137986"/>
            <dbReference type="ChEBI" id="CHEBI:137990"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.29"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>[L-4-(L-arginin-2-N-yl)aspartate](n)-L-aspartate + ATP + L-arginine = [L-4-(L-arginin-2-N-yl)aspartate](n+1) + ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:23888"/>
            <dbReference type="Rhea" id="RHEA-COMP:13732"/>
            <dbReference type="Rhea" id="RHEA-COMP:13733"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:137986"/>
            <dbReference type="ChEBI" id="CHEBI:137990"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.30"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the C-terminal section; belongs to the MurCDEF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.29" evidence="7"/>
    <dbReference type="EC" id="6.3.2.30" evidence="6"/>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071161">
        <property type="term" value="F:cyanophycin synthetase activity (L-arginine-adding)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071160">
        <property type="term" value="F:cyanophycin synthetase activity (L-aspartate-adding)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009059">
        <property type="term" value="P:macromolecule biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013651">
        <property type="entry name" value="ATP-grasp_RimK-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011810">
        <property type="entry name" value="Cya_phycin_syn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044019">
        <property type="entry name" value="Cyanophycin_syn_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18921">
        <property type="entry name" value="Cyanophycin_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08443">
        <property type="entry name" value="RimK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02068">
        <property type="entry name" value="cya_phycin_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="12" id="KW-0436">Ligase</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="11">
        <location>
            <begin position="221"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TXD88053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="877" mass="96347" checksum="E1FC220982912C9E" modified="2019-11-13" version="1">MNIREINAMRGPNYWSVRRHKLIVMVLDLEDMEQKPSDKIDGFYERLTTMFPTMYSHRCSVGSPGGFFERVKDGTWMGHVIEHIALEIQTLAGMDVGFGRTRGYGEEGVYNVVFAYMEESVGRHAAYASVAICEALIAAEDYDLEPDLQKMRELREADRLGPSTGSIVAEAEARGIPWIRLNKYSLCQLGYGANQKRIQATVTSETSSIGVELACDKEDTKYLLEHAEVEVPKGDIIRKESSLEDACKYVGFPLVIKPIDGNHGRGISVDVKNYEDALVAFHAARAISRAVIVEKFITGADYRLLVINHKLVAGAKRTPAHVIGNGNSTVQELIDEVNKDPRRGYGHENVLTKITVNDLTLTIIKDAGYDLESVVPKGERLVLKDTANLSTGGTAEDITDIIHPANVSMAERISKIIDLDICGIDIMTSDISQPLSDTGGAVLEVNAGPGFRMHLAPTTGLPRNVAAPVIDKLFPKHGDTGCIPIIAITGTNGKTTTSRLVAHIAKMNGYRVGYTTSDGVYIQNRLLMSGDCTGPTSAEFVLKDPTVNFAVLECARGGLLRAGLGFKHCDVAIVTNVSADHLGLKGIHTIDQLARVKGVVPETVRPGGYAILNADDDLVYDMRRSVNCHVALFSMDENNPRIKAMQRLNGVTAIYEHGFVTICRGEWKMRIMNAENIPLTYGGKAKFMIQNVLAAILAAHVQGISIEDMKAGLETFIPSASQTPGRLNMFKFKDFSILLDYAHNPSGMRALHEFTKELEATVKVGIIAGIGDRRVEDNNEMGSIAAEMFDEIIIRQDKRLRGKTEEELIKMLHDGIKMKDPNKKTTIIPSEKEAITYAVKNAVKGSLIILCSDVIPDALDLVKEFKELESRGELKFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGT3</accession>
    <name>A0A5C6ZGT3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">TPM domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_12330</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007621">
        <property type="entry name" value="TPM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04536">
        <property type="entry name" value="TPM_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="TPM_phosphatase" evidence="4">
        <location>
            <begin position="6"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD88524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="145" mass="16689" checksum="EEF18F1A82D743B7" modified="2019-11-13" version="1">MSEIEKFLDKKDEEAIIEAIRDAEKNTSGEIRVHIEATTKLDVFDRAMEVFHYLKMDNTKQQNGVLIYVAVHDKTFVIYGDKGINDVVEDDFWDSTKDIMQSHFKSGNFKQGLVDGITKAGQQLEQHFPWQHDDKNELPNTISKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGX9</accession>
    <name>A0A5C6ZGX9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 9">GTPase Der</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">GTP-binding protein EngA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">der</name>
        <name evidence="11" type="ORF">ESY86_12345</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 9">GTPase that plays an essential role in the late steps of ribosome biogenesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Associates with the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8 9">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00195">
        <property type="entry name" value="GTPase_Der"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031166">
        <property type="entry name" value="G_ENGA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016484">
        <property type="entry name" value="GTP-bd_EngA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032859">
        <property type="entry name" value="KH_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14714">
        <property type="entry name" value="KH_dom-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006485">
        <property type="entry name" value="GTP-binding_EngA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03594">
        <property type="entry name" value="GTPase_EngA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51712">
        <property type="entry name" value="G_ENGA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5 7 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 7" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="EngA-type G" evidence="10">
        <location>
            <begin position="3"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="EngA-type G" evidence="10">
        <location>
            <begin position="177"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="9"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="56"/>
            <end position="60"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="119"/>
            <end position="122"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="183"/>
            <end position="190"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="230"/>
            <end position="234"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="295"/>
            <end position="298"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD88526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="436" mass="49705" checksum="E483B378A30DFDEF" modified="2019-11-13" version="1">MSSIVAIVGRPNVGKSTLFNRLIQRREAIVDAVSGVTRDRHYGKSDWNGREFSIIDTGGYVKGSDDVFEVQIDRQVVLAIEEADVILFMVDVESGVTGMDEDVAKLLRKVEKPVLLVINKVDNNKRAEDAVEFYSLGLGEYFTIASINGSGTGDLLDAVVEALPKEVARDTEEAQLPRFAVVGRPNAGKSSFINALIGEERYIVTDIAGTTRDSIDTKYNRYGFEFNLVDTAGIRRKSKVKEDLEFYSVMRSVRAIEHCDVCIVILDATRGFDGQVQNIFWLAERNRKGIVILVNKWDLVEKNTLSTRDFEREIKKELEPFTDVPIVFISVLNKQRIYKAIETAVEVYNNRTKKIKTSKLNEVMLPIIENYPPPAYKGKFVKIKYIMQLPTPQPQFAFFCNLPQYVRPPYKRYLENKLREEFDFHGVPISVYMRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH00</accession>
    <name>A0A5C6ZH00_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phospho-N-acetylmuramoyl-pentapeptide-transferase</fullName>
            <ecNumber evidence="7">2.7.8.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">UDP-MurNAc-pentapeptide phosphotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">mraY</name>
        <name evidence="8" type="ORF">ESY86_09375</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>di-trans,octa-cis-undecaprenyl phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine = di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UMP</text>
            <dbReference type="Rhea" id="RHEA:28386"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:60392"/>
            <dbReference type="ChEBI" id="CHEBI:61386"/>
            <dbReference type="ChEBI" id="CHEBI:61387"/>
            <dbReference type="EC" id="2.7.8.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the glycosyltransferase 4 family. MraY subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.13" evidence="7"/>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008963">
        <property type="term" value="F:phospho-N-acetylmuramoyl-pentapeptide-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051992">
        <property type="term" value="F:UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine:undecaprenyl-phosphate transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06852">
        <property type="entry name" value="GT_MraY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00038">
        <property type="entry name" value="MraY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000715">
        <property type="entry name" value="Glycosyl_transferase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003524">
        <property type="entry name" value="PNAcMuramoyl-5peptid_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018480">
        <property type="entry name" value="PNAcMuramoyl-5peptid_Trfase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22926">
        <property type="entry name" value="PTHR22926"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00953">
        <property type="entry name" value="Glycos_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10555">
        <property type="entry name" value="MraY_sig1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00445">
        <property type="entry name" value="mraY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01347">
        <property type="entry name" value="MRAY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01348">
        <property type="entry name" value="MRAY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0133">Cell shape</keyword>
    <keyword evidence="7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="75"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="136"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="216"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="245"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="281"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="308"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="335"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="389"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD89245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="411" mass="45845" checksum="15FA35B475433B24" modified="2019-11-13" version="1">MLYYLFEYLDQQFDLPGTGVFQYTTFRAALAILFSLLFSTIFGKKIINYLQKQQVGETVRDLGLAGQVEKAGTPTMGGIIIILGTLVPVLLLSRLDNIYVIMLIVTTIWMGMIGFIDDYIKVFKKDKEGLSGKFKVLGQVGLGIFVGAVMYFHPGVTVKYEKVNTENSIEAIGQDSSQEFYGEESGSMKTTIPFVKDNEFDYAKLLIWLGDDYEDYAWLIFIPIVIFIVTAVSNGANLTDGIDGLAAGSSAIIVFALAIFAFVSGNIMLSDYLNVMFIPRLGELVVFIAAFVGALIGFLWYNTYPAQVFMGDTGSLTIGGIIAVIAIAVRKELLIPVLCGIFFAESLSVIFQVSWFKYTRRKYGEGRRIFKMSPLHHHYQKSGYHESKIVTRFWIVGIFLAIISIVTLKLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH04</accession>
    <name>A0A5C6ZH04_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_10660</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="10"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="146" mass="16840" checksum="DF8D02084F0B9F2A" modified="2019-11-13" version="1">MDNQKIKFAHILLVEDNEGDILLTKEAFEECKVKTEISVAKNGQEALDFLFKRGAYVDVKKPDLILLDINLPIYNGHEVLRQIKADPRLKKIPVIVLTTSSNQKDLDEAYENHCNSYVKKPLEINEFLNAILKIEEFWLQLTLLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH17</accession>
    <name>A0A5C6ZH17_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3 4">Single-stranded DNA-binding protein</fullName>
            <shortName evidence="2">SSB</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ssb</name>
        <name evidence="6" type="ORF">ESY86_08650</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04496">
        <property type="entry name" value="SSB_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00984">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000424">
        <property type="entry name" value="Primosome_PriB/ssb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011344">
        <property type="entry name" value="ssDNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10302">
        <property type="entry name" value="PTHR10302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00436">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002070">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00621">
        <property type="entry name" value="ssb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50935">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="108"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="108"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="140"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR002070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD89441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="154" mass="17667" checksum="9B4D8D8C0F648D63" modified="2019-11-13" version="1">MSGTLNKVMLIGHLGDEVKMHYFEGGNCIGRFPLATNETYTSKQTNERVTNTEWHNIVVRNKAAEICEKYLSKGDKVYIEGRIKTKKWQDDKGMDRYSTEIQCTEFTFLSTKNEGQTGTTPPQANQQSNEQTQHQTSNQTTEKPKEEDHDDLPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH48</accession>
    <name>A0A5C6ZH48_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nuclear transport factor 2 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_08810</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027843">
        <property type="entry name" value="DUF4440"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14534">
        <property type="entry name" value="DUF4440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022759890" evidence="1">
        <location>
            <begin position="20"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4440" evidence="2">
        <location>
            <begin position="40"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="154" mass="17634" checksum="30497FEF38FD0356" modified="2019-11-13" version="1">MKSTLKILMIVLIVFQTFAQSNEVVKPSEAKPIETAKLEIKKVLQAQEIAWNQHDLEGYMAGYWKNDSLKFFGSRGLTYGWDSTLANYKKSYPSKAETGTLTFSIQDISKIEDDNYWVMGKYHLTREAGDANGLFMIIFRKIDGEWKIIADMSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH51</accession>
    <name>A0A5C6ZH51_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Zinc-dependent peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_09220</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20169">
        <property type="entry name" value="Peptidase_M90_mtfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010384">
        <property type="entry name" value="MtfA_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042252">
        <property type="entry name" value="MtfA_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30164">
        <property type="entry name" value="PTHR30164"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06167">
        <property type="entry name" value="Peptidase_M90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="255" mass="29834" checksum="A10F517E068A0F69" modified="2019-11-13" version="1">MVYILIFILLVVFVGYSFYKMRDRKAEPFPGHWHGLMMEEVAFYKALQPKEQTRFQKRTMQFLSEVYVDGVDLEVTDLDRILLAASAVIPVFGFKEWHYKNLSGILIYPDNFNEDYQFSDSSKERRISGVVGSGRLERQMIISKIALHHGFRNSRDKRNTAIHEFAHLIDKMDDRVDGVPEVLLQNVYTIPWLKMIHDEMEAINNNQSDIRAYGGTSQAEFFAVASEYFFERPKLMKRKHPKVYKMLNLCFGLKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHB2</accession>
    <name>A0A5C6ZHB2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_08250</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021860">
        <property type="entry name" value="Peptidase_S12_Pab87-rel_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11954">
        <property type="entry name" value="DUF3471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022836979" evidence="1">
        <location>
            <begin position="21"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase" evidence="2">
        <location>
            <begin position="31"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3471" evidence="3">
        <location>
            <begin position="419"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="516" mass="57771" checksum="52827332EF7EE37F" modified="2019-11-13" version="1">MNIKNYLALLLLVTCISLNAQIEEQKLDTLIEQTLSTFEVPGISVGILKDGKIVYAKGKGVRSLTSNKDMNATTLVGIASNSKGFTCVALAMMVDEGKLNWDDTVRKYIPEFQLHDAWVTKHFTIRDLVTHRSGLGLGAGDLMFFPENNSFSTEDILANLKYLEPESSFRSAFEYNNNMYIVAGEVLKRLSGLSWEEFIETRILKPVGMSSSKASYNRVTDKSNIIEAHTMADGKVIQIPHDWSDTANPAGGIVSNIPDMLTWAKFLMDGAVTAEGERLLSEKQLNELWQLQMPLKVSANDSYGSNFRGYGLGWFLTDVKGGHKQVYHTGGLLGTVTQFTMIPDMNLAIVVLTNQMNGSAFNSITNTIKDSYLGYDDRNWLKRLGDSNTNFITYNDSIKTAVYDEVKLAKTNKAFPKPEQIVGTYTDDWFGDIRISHNGNSYSISSKRSKTLIGELLPYNYSSFIAKWNNRSYDADVFVNFTFDETGKAIGARMKPIAPITDFSFDFEDLEFKRTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHH0</accession>
    <name>A0A5C6ZHH0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Type II toxin-antitoxin system HipA family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_07440</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HipA Ser/Thr kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012893">
        <property type="entry name" value="HipA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017508">
        <property type="entry name" value="HipA_N1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13657">
        <property type="entry name" value="Couple_hipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07804">
        <property type="entry name" value="HipA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Couple_hipA" evidence="4">
        <location>
            <begin position="8"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="HipA_C" evidence="3">
        <location>
            <begin position="167"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD89612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="420" mass="48038" checksum="648FF5B6383A1A24" modified="2019-11-13" version="1">MARDNIIDIIAFGLEVGKLGYDLDQRKSYFQYHPEFLETGKYSKLFPFIFKRTKEAQVFTEYQQDTFQGLPPMIADSLPDTFGTIIFQEWLTARGIQKITPLEQLAYVADRGMGALEYRPIKEIPNTTHVNIDEVITILEKLLKLKEDTTGKDLNELSLLHVFKIGTSAGGARPKILISEHKETGAVIAGDRAISEDYNHYLVKLHIDDSDGYNREKVEYAYYLLAQETGIHMMPSKLIENKHFATLRFDRQHGKKQHMLTVTGLTGWDFKSQPDNSSYENVFKVALGLEVPHKDLQQLFKRMVFNLVFRNVDDHLKNHSFIYNKESNSWNLGPAYDLTYALDPLFTFKTTSRALSINGKRTAILIKDVLAIAEEFSIKNPKGITEDVQALIPRWAEIASELEINETIINAIQSDLKILE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHH1</accession>
    <name>A0A5C6ZHH1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">SusC/RagA family TonB-linked outer membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_13430</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011662">
        <property type="entry name" value="Secretin/TonB_short_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023996">
        <property type="entry name" value="TonB-dep_OMP_SusC/RagA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023997">
        <property type="entry name" value="TonB-dep_OMP_SusC/RagA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00965">
        <property type="entry name" value="STN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04056">
        <property type="entry name" value="OMP_RagA_SusC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04057">
        <property type="entry name" value="SusC_RagA_signa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0732">Signal</keyword>
    <keyword evidence="3 6" id="KW-0798">TonB box</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023040447" evidence="7">
        <location>
            <begin position="18"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="domain" description="STN" evidence="8">
        <location>
            <begin position="48"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD88339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1073" mass="117911" checksum="A77547B9FC6696EE" modified="2019-11-13" version="1">MRTFLLLITIGLGTAFANTSEAQTKMDISVTNVSLEQLFKEIQSKSEYIFFYKDAIFDYRVSLNLKASTVAGILDKALADTDLTYMINERQIVIKSKLETPAEALKTNQQLREITGTVSDPNGTPLAGATVIVKGTTKGASTDFDGNFKLDVPIDTKTLVVTYLGYVAQEVSIEGKSELNITMLEDNTALEEIVVIGYGTEKRALISDAITTVSAKQIEDLPLGSVDAVLQGQAAGVQVSQNSGTPGGEMSVRIRGLTSISGSSQPLYIIDGIPVTTGDYGQIGYSGQGASALTDLNPSDIESISILKDASATAIYGARASNGIVLITTKRGKVQETVVSVNAYSGMQRAWNKLDMLNAREWMEYRNDLTNSTVFTQEQINNNQVDTDWQDVIFRTAPINSYEVSARGGTEKTQFFMSGTLFEQEGILIGTDYSRVNARVNVDHQISDKFKIGASIGLSYAKTDRVESDQSLHGPLPNGISTPAIFPVFNEDGSYNQDGPYSNPLSIANEAINENFSYRTNSNFYFDYYITDYLTLSSKLGVDFLNFREHGYESTRTVQGAKFNGLGFETYSNISNIVSNNLLKFNKRFGQHKIEALVGYSFEKRNFRSSFIRGQDFADDDLEYINSAATIVSASASAADEGLRSSFGRVNYNFSDKYIATVTGRFDSSTKFGENNQTGFFPAASLAWRASQEEFLKNSRVISDLKLRVSYGLTGNDDISPFLFSELYGNTSYGGSPAIFPSNIPNPDLKWESTTQLNIGLNLGLFKDRITLTADYYDKQTNDLLLSRPLPPSSGFSSITENVGKVENKGIELTIASQNFIGEFKWNTQFNISGNRNKVLELYNGQPIDDIGRGGNRIMEGQPIGVFYSFESLGVDPSTGDIVYADTNFDGVITSADRTIVGDPHPDFIGGLTNNFSYKGIDLTVFLQGSYGNDVFHGSRLFLESLQGGDNQVAAVTRRWMQPGDITDIPRATTDAVAAAQNKRVSSRFLEDGSYLRIKNVTLGYTVDKRALDKSFFESIRVYVSAQNMFTFTNYTGLDPEVNYRGDDNSVIGTDFFTYPQAQTITLGVNLKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHH6</accession>
    <name>A0A5C6ZHH6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_09010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022687138" evidence="1">
        <location>
            <begin position="26"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="115" mass="13065" checksum="AA058E5A9EF437B7" modified="2019-11-13" version="1">MKTKSIAIVSLLVLCFFTLTSLRSATQETMTFEGTYDGHEDYGYNFIGTDTDDNEYTMTFQDIDAKLLSNFDLKSEALVGKKFTVTYTIESEVVTDEDGYDEETETYSIVNLKQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHH8</accession>
    <name>A0A5C6ZHH8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_09025</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="311"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="345"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="379"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="440"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="471"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="496" mass="57204" checksum="C2059E7CCB524DC0" modified="2019-11-13" version="1">MILETIIIVIYSIAIVLIFMYSLAQLNLLNNYLSSKKKQQSCETFDFENPEEVPLVTIQLPVFNEMYVMERLLDNIALLDYPKNKLEIQVLDDSTDETVATTRAHVAALKKTGLDIQHITRTDRSGFKAGALKEGLKVAKGEYIAIFDADFLPKQNWLKSTIPFFKDEKIGVVQTRWGHINRNYSLLTKIQAFALDAHFTLEQVGRNSKGHFINFNGTAGVWRKTCILDAGNWEGDTLTEDLDLSYRAQLKNWKFKYLEDVETPAELPVVISAARSQQFRWNKGGAENFRKMLWKLVKSDNISNKTKIHGLLHLLNSTMFLNVFIVAVLSIPMLYIKNEYEHLRFYFYFMSFFVTSTIIFFVCYWFMYKQIYGSGFKKFFNYIGMFFTFFAIAMGFSLHNSIAVLEGHSGKRSEFVRTPKFNINSIKDSWKGNKYLRKKLSINVFIEGALMLYFAFGLYSAFVVGDKGGDFGLFPFHLMLFLGFGYVFFTSITSKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHI0</accession>
    <name>A0A5C6ZHI0_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">1,4-alpha-glucan branching enzyme GlgB</fullName>
            <ecNumber evidence="9">2.4.1.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">1,4-alpha-D-glucan:1,4-alpha-D-glucan 6-glucosyl-transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Alpha-(1-&gt;4)-glucan branching enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Glycogen branching enzyme</fullName>
            <shortName evidence="9">BE</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 12" type="primary">glgB</name>
        <name evidence="12" type="ORF">ESY86_11455</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>Transfers a segment of a (1-&gt;4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain.</text>
            <dbReference type="EC" id="2.4.1.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Glycan biosynthesis; glycogen biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.18" evidence="9"/>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00164"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003844">
        <property type="term" value="F:1,4-alpha-glucan branching enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102752">
        <property type="term" value="F:1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043169">
        <property type="term" value="F:cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02855">
        <property type="entry name" value="E_set_GBE_prok_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00685">
        <property type="entry name" value="GlgB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006048">
        <property type="entry name" value="A-amylase/branching_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037439">
        <property type="entry name" value="Branching_enzy"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006407">
        <property type="entry name" value="GlgB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044143">
        <property type="entry name" value="GlgB_N_E_set_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004193">
        <property type="entry name" value="Glyco_hydro_13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43651">
        <property type="entry name" value="PTHR43651"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02806">
        <property type="entry name" value="Alpha-amylase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02922">
        <property type="entry name" value="CBM_48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000463">
        <property type="entry name" value="GlgB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01515">
        <property type="entry name" value="branching_enzym"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7 9" id="KW-0320">Glycogen biosynthesis</keyword>
    <keyword evidence="4 9" id="KW-0321">Glycogen metabolism</keyword>
    <keyword evidence="5 9 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aamy" evidence="11">
        <location>
            <begin position="157"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9 10">
        <location>
            <position position="315"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="9 10">
        <location>
            <position position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000463-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TXD88845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="636" mass="73365" checksum="A70954FE7ADE1E52" modified="2019-11-13" version="1">MSKVIAHSRFTEFDINLFKAGKHYRLYEKFGAHISTVDGVDGVYFAVWAPSAKTVSVIGDFNFWVEGTHQLNVRWDSSGIWEGFIPGAGKGSTYKYKIHSNNNDVKTEKADPYARRSEHNPKTASIVWDDPYQWKDSKWMKKRKKNNALDAPFSVYEVHLGSWKRKLEGNSVLTYSELAEDLVSYVKDMNFTHVELMPVMEFPYDPSWGYQITGYFAPTSRFGYPEDFKLLVDKLHQNDIGIILDWVPSHFPEDAHGLGFFDGTALYEHPDRRRGYHTDWKSLIFNYGRNEVKSFLISNAIFWLDQFHADGLRVDAVASMLFLDYSREDGEWEPNIFGGRENLEAMAFLREMNDAVYTAFPDVQTIAEESTAFPMVSKPTSIGGLGFGMKWMMGWMHDTLQYFAKPPVYRKFHQNDLTFSMTYAFTENFMLPLSHDEVVYGKKSILGRMPGDEWQRFANLRLLYSYMFTHPGTNLLFQGAEFAQSKEWNFEQSLDWHLLDYAPHQGIQALIKDLNGLYKSQPALHEKQFSAEGFEWIDYNDHENSVLVYIRKSDDEKDDLIIACNMTPVPKESYRIGLPKKGNLKERFNSDQKKYFGSGAYKNSKLSSEAVAHHFRDHSVEIAIPPLGMVVFGYGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI12</accession>
    <name>A0A5C6ZI12_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Aminotransferase class V-fold PLP-dependent enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_11265</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4 5">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the group II decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010977">
        <property type="entry name" value="Aromatic_deC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00800">
        <property type="entry name" value="YHDCRBOXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3 5" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="4">
        <location>
            <position position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR602129-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD88811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="478" mass="53764" checksum="570E92B847789475" modified="2019-11-13" version="1">MIPDKETSHTLQLSKDEMKQYGYQVIDAIVDHFDTERSKKPVALASREEMDTLFNREVPEDPTDFQTVFDLVTQKVLPNSNIVTHPKSYSFVPGPSNYVSVMADTLATGFNVFSGGWAGSPAAAELEIVTMNWLLKLFKFPKKKGGGIFTSGGSMANLTALVTARGQKLGDDFSKAVIYMSDQAHSSNIKAIRVLGFKKEQVRIIPTDMEFKMAINKLKSAIAIDKLEGLEPFCIIASAGTTNTGTVDPLLEIAKICKSEDLWYHIDGAYGGAAILSEKGKQELKGIEKADSLTIDPHKWMFQPYEMGCLLVRNHKWLSETFSEKPEYLRDIEGNTSEINFYDHGIQLTRRFRALKFYMSVKTFGLNAFKRAVSYNIEITERVEDLLRTSAKWEVISPATLAVINFRYNPLGKNYSEKELDRINQQISEKVVASREALLVTTVLQNQVVLRMCLINPRTTMEDIKETINLCESFAEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI23</accession>
    <name>A0A5C6ZI23_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Antibiotic biosynthesis monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_10825</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="97" mass="10987" checksum="67F2B20DF83A4161" modified="2019-11-13" version="1">MLRYGIKVTLKAKKETTAEVEDFIKGAVELAQKEEQTITWYSFKVDAHTFGIFDTFETEEGREAHLNGDIAKALMEHADRLLSEAPVIEKIDILSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI28</accession>
    <name>A0A5C6ZI28_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_11375</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="97" mass="10866" checksum="BE37429D66A3B818" modified="2019-11-13" version="1">MRCGFGFCYDSNLNISFDCEPNTPKVSPRTENAAYNSTTQETKAVGVYDPVKNEIVFYFDKNSVGPPNHQPSDFTTLDVGVGFYLTSKIKLVEWILS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI57</accession>
    <name>A0A5C6ZI57_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GTPase HflX</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">GTP-binding protein HflX</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">hflX</name>
        <name evidence="9" type="ORF">ESY86_08345</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer. Associates with the 50S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="5">May associate with membranes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01878">
        <property type="entry name" value="HflX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00900">
        <property type="entry name" value="GTPase_HflX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030394">
        <property type="entry name" value="G_HFLX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032305">
        <property type="entry name" value="GTP-bd_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016496">
        <property type="entry name" value="GTPase_HflX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025121">
        <property type="entry name" value="GTPase_HflX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042108">
        <property type="entry name" value="GTPase_HflX_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10229">
        <property type="entry name" value="PTHR10229"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16360">
        <property type="entry name" value="GTP-bdg_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13167">
        <property type="entry name" value="GTP-bdg_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006809">
        <property type="entry name" value="GTP-binding_hflX_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03156">
        <property type="entry name" value="GTP_HflX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51705">
        <property type="entry name" value="G_HFLX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hflx-type G" evidence="8">
        <location>
            <begin position="200"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="206"/>
            <end position="213"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="231"/>
            <end position="235"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="252"/>
            <end position="255"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="318"/>
            <end position="321"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="363"/>
            <end position="365"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR006809-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR006809-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD89389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="404" mass="46536" checksum="98B149D6DEC9961B" modified="2019-11-13" version="1">MIEKKDIELEKAVLIGVITKDQNEEQSTEYLDELEFLTYTAGGEVLKRYTQKIDVPNPKTFIGTGKMKEVQQYIEEHAVGTAIFDDELSAAQERNISKILNCKVLDRTNLILDIFAQRATTSYARTQVELAQCEYLLPRLKGMWTHLERQKGGIGMRGPGETEIETDRRIVRDKISLLKDKIKTIDKQMAVQRGNRGKMVRVALVGYTNVGKSTLMNVISKSDVFAENKLFATLDTTVRKVVIQNLPFLMTDTVGFIRKLPTQLIESFKSTLDEVREADLLLHVVDISHPNFEEHIESVNKILGEIDSADKPIIMVFNKIDAYKAEPLEEDDLVTVKTEQHYTLEEWKRTWMNRVGDNALFISALNKDNLDSFKKRIYDEVREIHVTRFPYNNFLYPDYSDEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIC6</accession>
    <name>A0A5C6ZIC6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4242 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10735</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3090">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025336">
        <property type="entry name" value="DUF4242"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042557">
        <property type="entry name" value="SCO4226"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14026">
        <property type="entry name" value="DUF4242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="264"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="362" mass="41184" checksum="F40F208643A8AC4B" modified="2019-11-13" version="1">MPLFMDFHDLPDGVSAKHVAEMHQADLDIEHKYCCRGLTYWCDEKRQTAFCLIDAPNKQAVVDLHQNSHGAVPQRIIEVNDTIVESFLGRIEDPEKSKNTKLNIINDPAFRTIVVVKIKQISLRISQKNILNAALRGYTSTINTLTSQYNGRLVRQEGYTFLMSFKSVTEAIHCGIDIQDSHNWVITPDLVFKIGISAGLPVTEKEGLFEDNIKTSDSLSDMAEGNFTITTAVKDLYEGENQNKSISKHPEINVLKPSEENFIRLLMDYTEKIWSHNATSVNDFQANLGYSKSRLYRSMMHLVGKSPNNFLRDYRLNKALELLQKQSYNIAEIAYQIGFSSPAYFSKCFHKKYGILPSSFPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZID2</accession>
    <name>A0A5C6ZID2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">GTP cyclohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_11890</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039968">
        <property type="entry name" value="YghO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41368">
        <property type="entry name" value="PTHR41368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="374" mass="44225" checksum="8609B74391A7933F" modified="2019-11-13" version="1">MISIKEIQSKSDLSKFVKFPFKLYKDSKYWVPPIIKQELETFNKEKNPIFKDAEARFFLAYKNDEIVGRIAAIINWLEVNNQKQKKMRFGWFDFIDDPEVSKALLTEVERIGKENNLDYTEGPVGFSNLDKVGVMTEGFDSIAPMITWYNHPYYAKHYEDFGYVVEKHYSESRFPFENVKPEFFKKAQELIKRRYDLKPLHLTKTEDVMPYADKMFDLFNKSYSSLSSFVAITDIQKEYFKQKFISFVNPEYIKFVVDKHDELVGFAIVMPAFSKALQKAKGKLFPFGFGHILNAKKNSKDVIFYLIGIHPDYQNKGVHAVIFNEYYETFRKKGIQTCFRTPELEDNDAIHKIWKHFDPVVYKRRKTFRKSLNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIG4</accession>
    <name>A0A5C6ZIG4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">EI24 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07505</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="205"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="264" mass="29614" checksum="73A68D41BBC7199C" modified="2019-11-13" version="1">MINNIFRGIQAYSGVFKLMASLKLWKYFFVPILISILTASLIGFSAYGLSDDIGRFIAKIWIWDWGKDSFTSFSSVLGGIMVLVIGLIVYKHIIMAFSAPFMSPVSEKIEAHLTGIQKHEHRKTSFQQQLWRGLRINGRNLVKELLISIPLLLLKFIPVVNIFSTILLFLVQAYYAGFGNMDYTLERHFNYKESLNFVKQHRGVAIGNGLVFMLFLFIPGIGIILVLPLSVTAASIKTVNLLQTEGLLPAAASGKMLRKEGHSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIH7</accession>
    <name>A0A5C6ZIH7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fasciclin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_09215</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02469">
        <property type="entry name" value="Fasciclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00554">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="SSF82153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50213">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAS1" evidence="2">
        <location>
            <begin position="58"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="206" mass="21834" checksum="7682C0DF6EBEE825" modified="2019-11-13" version="1">MKRIFTSVMCLTLVFMTACKDGKAEEEAAAKMEQEKMDQENADNETAMQEEAMREAQENSIASKAMATESLSTLVAAVKAADLATMLSEPGDYTVFAPNNAAFDKLPAGTVETLLKPENKEQLKGILTYHVVPSKVDANTLIAAINDSDGKYVVKTANGGELTATLSGESVILTDASGNKSTIIATDVQASNGVVHIIDTVVMPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIK5</accession>
    <name>A0A5C6ZIK5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_07790</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD89673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="235" mass="25943" checksum="582B967F676769F5" modified="2019-11-13" version="1">MIQTTALSKSYGSKTVLTINELHIPKGQSFGLVGNNGAGKTTYFSLLLDLIKPTTGQITNNGIIVSESEDWKPFTSAFIDESFLIGYLTPEEYFYFIGELRNQNKADVDALVAQFADFFHGEILNQKKYLRDLSKGNQKKVGIVAALIGNPEVIILDEPFANLDPTTQIRLKGIIKDLAEKQGVTVLVSSHDLLHVTDVCERIVVLEKGEVIKDLATNEATLKELEVHFSGETLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIL6</accession>
    <name>A0A5C6ZIL6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nitrous oxide reductase family maturation protein NosD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">nosD</name>
        <name evidence="3" type="ORF">ESY86_11175</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006633">
        <property type="entry name" value="Carb-bd_sugar_hydrolysis-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026464">
        <property type="entry name" value="NosD_copper_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007742">
        <property type="entry name" value="NosD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022441">
        <property type="entry name" value="Para_beta_helix_rpt-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05048">
        <property type="entry name" value="NosD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00722">
        <property type="entry name" value="CASH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04247">
        <property type="entry name" value="NosD_copper_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03804">
        <property type="entry name" value="para_beta_helix"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023118555" evidence="1">
        <location>
            <begin position="20"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="domain" description="CASH" evidence="2">
        <location>
            <begin position="48"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="CASH" evidence="2">
        <location>
            <begin position="194"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="411" mass="46697" checksum="442AE7038ECF9C34" modified="2019-11-13" version="1">MKKLVVFFTIIFMTGASLAQTLEVCTTCPISSLKAAIAKAKAFDTVVVKKGRYNEYDVVIDKPLTIIGKNHPVIDGKNKGEIITIVSDSVTVDGLHLINVGTSYTEDYAAIRVKSSAHFVIRNLILEKLFFGIYIEKSNHGKIRNNKIIGDAVEEYNSGNGIQLWYSKHVDIEDNIVQHVRDGIYLEFSDFCTIKNNLSSLNVRYGLHFMFSNDDVYQDNEFSNNGAGVAVMFSKRIKMYNNLFKDNWGSASYGMLLKEINDSEIIGNTFEDNTVGINIEGSNRIIYKHNNFSNNGWAIKVRGACYANTYTENNFLYNSFDMAYNSNVNDNTFDRNYWSNYTGYDLNKDGVGDVPYRPVKLFTYIVNRTPETIILLRSMFIDIIDFSEKVSPVFTPDDLLDNNPLMKKVTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIM9</accession>
    <name>A0A5C6ZIM9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyltransferase family 4 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_09780</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="370" mass="43163" checksum="D314F8D6E07917A6" modified="2019-11-13" version="1">MILYYFGADTAWHEQSAAALNRRNMALLFALSNQESISTVYNVIRSTRSTVFKNRKKQKLATTKIINVYVAPIFPERGFLNHITRPINRMLLKMMHPKVFEASTVGKKLAWCYWPKGFEDFEFMGIDMELIFDTDHNIIDEPNIGNEKKEERRLLLLRAGKKAKYILSSSRSMINWYQQYGLSNTKILMNGLFEERVNLTPNLKENKNYVVTYCGTLSKWLKLDWLFKILHERPEWSFNFIGANYQTDITTQLEEFSNVNLCGFLNPKQVDEILKQSDVCFGLYQKDPSVDVNSMKLYDYLAQGIPVVVNNYHSNLKEDFNDLLNIANTYEEFESLLANPKQMNLNKVEQFLEASTWNYRVKNIINGILA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIV7</accession>
    <name>A0A5C6ZIV7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">S1/P1 nuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_06355</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11010">
        <property type="entry name" value="S1-P1_nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.575.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008947">
        <property type="entry name" value="PLipase_C/P1_nuclease_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003154">
        <property type="entry name" value="S1/P1nuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33146">
        <property type="entry name" value="PTHR33146"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02265">
        <property type="entry name" value="S1-P1_nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48537">
        <property type="entry name" value="SSF48537"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD89823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="259" mass="29767" checksum="11DA612E4DC3527B" modified="2019-11-13" version="1">MKSSFFALLFTISILTTYANTQPTWGRTGHRVVGAIADNYLNNSTKRKIEKILNHESLALVSTFPDEIKYDERYDQFKTWHYVNMSLDETYGTSEKNPEGDMVTGIEFCKQVLTNENSTAADKAFYLKMLIHLIGDLHQPMHLGLKEDRGGNDFDVQWFYKDSNLHKVWDSQMVEGYDMSYSELVTNSPYLSKDEIEAIERGSLSDWVTETHKLTKIVYASAEKGDNLRNEYAFKYLGLAREQMQKAGIRLAVVLNDIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIW3</accession>
    <name>A0A5C6ZIW3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF3883 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024975">
        <property type="entry name" value="NOV_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13020">
        <property type="entry name" value="DUF3883"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3883" evidence="1">
        <location>
            <begin position="374"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="494" mass="57102" checksum="048BAF6B779E7F51" modified="2019-11-13" version="1">MIEEISREELNSLDRSSLLFLKNLNEVHIDYKNIHRNIFVKHNYDENNDVVQLIEDEFVDEWKIQHLENNKTDLVAYKVENGVIVPALNEESVIHSFTPTNEFSGAFLKINGDYTTDPSRKSVDMDDLSKKSYNNAVKIIVKNIVDILNGDLSKQGFFTPFINIQTTDSNRFKNLLFNAIEEKLKSVIDSIRIKPDWLNFEDYEKVSKNGIKSISKNLVSTYPEIFTILKSLNAKTLSIKDILKNINDVNLSIIGYAEVYSKIIAQYRYDLDLKVIEQLKQLSLFPTKNGVLSAFQISKSNELDDNFINYLNNNVDVADVKLFFKKMETESNQNVSIVSDKKIEVQKAIDENPTLNKPFTFKVAPTIKKWRSSEKNAQEYLKALNVALSVKDVTEANLGYDLEMMLHNGKRIYIEVKSVNTFSEPFKISNNEYSSAHNYGSDYFIALVINNDNFKIKFVPNPIKTLSFEKKCERWSWFCAEYLNELQEIDQIIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIZ6</accession>
    <name>A0A5C6ZIZ6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_09500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022385">
        <property type="entry name" value="Rhs_assc_core"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03696">
        <property type="entry name" value="Rhs_assc_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="304" mass="33557" checksum="909B7D3CFE318C2B" modified="2019-11-13" version="1">MAMPNRNIVGDYRYDYQGQELDQETGKVAFELRLYDPRINRWLTTDPYGQYHSPYVGMGNDWINGIDPDGGWKTKWGRFWGWVGNGFKGEFYNSDVATGQGKYGLAFDYGGGSGEGELTGSFMAVSGADLDSWNGNQALNNWRFTEDGSGYDIAVIVQKQHNFFGSIENSLNNSDSALSSVGSMGYNMVDDVYSFGTHFSLLSPNGPRHLNGNGIVRGSSEGIDTGINGMLTIATFGRLKKPTMNMGQFNAEYKGVLTRTIKSSKIKGIILKNMNRLNKYWGRQVIAPNLKTVKGVSESIFGAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ04</accession>
    <name>A0A5C6ZJ04_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8 9">Chorismate synthase</fullName>
            <shortName evidence="8">CS</shortName>
            <ecNumber evidence="4 8 9">4.2.3.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">5-enolpyruvylshikimate-3-phosphate phospholyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">aroC</name>
        <name evidence="10" type="ORF">ESY86_11765</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8 9">
            <text>5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21020"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57701"/>
            <dbReference type="EC" id="4.2.3.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8 9">
            <name>FMNH2</name>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
        </cofactor>
        <text evidence="8 9">Reduced FMN (FMNH(2)).</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8 9">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8 9">Belongs to the chorismate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.5" evidence="4 8 9"/>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004107">
        <property type="term" value="F:chorismate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07304">
        <property type="entry name" value="Chorismate_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00300">
        <property type="entry name" value="Chorismate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000453">
        <property type="entry name" value="Chorismate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035904">
        <property type="entry name" value="Chorismate_synth_AroC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020541">
        <property type="entry name" value="Chorismate_synthase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21085">
        <property type="entry name" value="PTHR21085"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01264">
        <property type="entry name" value="Chorismate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001456">
        <property type="entry name" value="Chorismate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103263">
        <property type="entry name" value="SSF103263"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00033">
        <property type="entry name" value="aroC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00787">
        <property type="entry name" value="CHORISMATE_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00788">
        <property type="entry name" value="CHORISMATE_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00789">
        <property type="entry name" value="CHORISMATE_SYNTHASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 8 9" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0274">FAD</keyword>
    <keyword evidence="8" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0288">FMN</keyword>
    <keyword evidence="7 8 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0521">NADP</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="8">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="125"/>
            <end position="127"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="239"/>
            <end position="240"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="280"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="295"/>
            <end position="299"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="321"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD88638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="353" mass="38325" checksum="A4DE3A377AB0906C" modified="2019-11-13" version="1">MAGNSFGKLFKLTTFGESHGVAIGGIIDGCPAGIHLDFEAIQNEMDRRKPGQSEIVTQRKEPDTVEFLSGVFEGKTTGTPIGFTIHNTNQKSKDYSHIKDVYRPSHADYTYEKKYGVRDYRGGGRSSARETACRVVAGAIAKQMMPDIKIQAFTSSVGNIALEKPYQELDFSKTESNVVRCPDPETAERMISRIKAIRKEGNTIGGTVTCVIQNVPIGLGEPVFDKLHAELGKAMLSINAVKGFEYGSGFEGAKMKGTEHNDLFNDDGSTKTNHSGGIQGGISNGMDIYFKVAFKPVATVIQKQDALDASGNIVEMQGKGRHDPCVVPRAIPIVEAMAALVLADYLLLRKQES</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ97</accession>
    <name>A0A5C6ZJ97_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GAF domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GAF" evidence="1">
        <location>
            <begin position="21"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="152" mass="16829" checksum="F95C3482A229BC9C" modified="2019-11-13" version="1">MTFDPLKPQIKTIINQTTASTNERLLSICSLLEQQIPHYNWVGFYFKNGDKNELKLGPYVGAPTDHTIIPFGKGICGQVAVSNKNFVVPDVSAQDNYIACSINVKAEIVIPLFVNGENIGQIDIDSNTADPFTAEDERFLEFVCEEVAMMLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJA4</accession>
    <name>A0A5C6ZJA4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ATP-binding cassette domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_06455</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="2"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="318"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="246"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD89839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="541" mass="61638" checksum="AD3BD78BB51F79A2" modified="2019-11-13" version="1">MLSVSNLSVQFGKRVLFDEVSTTFHNGNCYGIIGANGAGKSTFLKILAGKQDPTSGHVHLEPSKRMSVLEQDHNLYDEHSVLETVLIGNKPLFKLKSEIDALYANYTDDNAEKIGELQVEFEEMNGWNADSDAAAMLSNLGIKEENHYTLMKDLDGKQKVRVLLAQALFGNPDVLIMDEPTNDLDYETISWLEHFLANYENCVIVVSHDRHFLDSVCTHISDIDFGKINHFSGNYSFWYESSQLAARQRSQQNKKAEEKKKELEEFIRRFSANVAKSKQATSRKKMIDKLNISDIRPSSRRYPAIIFDRDREAGDQILSVENLSASLDGEVLFHNIDINLNKGDKVVVYSRDSRATSAFYQIINNKEKADSGKYSWGVTTSQSYLPLDNSSFFDNNLSLVDWLRQWATTEEEREEVYIRGFLGKMIFSGEEALKTSNVLSGGEKVRCMLSRMMMVRANVLMLDEPTNHLDLESITAFNNSLKNFKGTIMFTTHDHEFAQTLATRVIELTPNGVIDRFMTFDDYMDDKKIKEHRDKMYAVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJG3</accession>
    <name>A0A5C6ZJG3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="62" mass="6845" checksum="6E3CF683294F974B" modified="2019-11-13" version="1">MADEKKIKNKDFDPGKDTDLEKGPLKSKHENAFGTRGKGSEKRDLSQDIPKKPGKSDTDAKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJJ4</accession>
    <name>A0A5C6ZJJ4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06945</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="188" mass="20530" checksum="6AD8EEABBDCC2937" modified="2019-11-13" version="1">MGFIKNNRNAIYGGIAATCFTGLGVFLVGNVSGYEAKNLLEVSLSGLNMLCNTIVLASATILALLLTLLSVSIGSTNSLKKRHYFQVLHIAKFDVILFISALILFQFFNIPIMESNEVPTSWYVSIYWITLGASSLISGMMITVILLLYNAVTNIIAIVGLGKEHELISTQDTSENSAEEQEKMKKEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJM0</accession>
    <name>A0A5C6ZJM0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03795</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022791857" evidence="1">
        <location>
            <begin position="20"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="147" mass="16516" checksum="A1C64514DB233BB2" modified="2019-11-13" version="1">MKHLIISLFLILSLQSCNTDDCGDCFTPPQPFLFELVDKSTGENAFTNGTYEPQQLNILDSITTAPVEYEFISENNVNLIQLNTIGWKTETVNLSFEISGNQIFNFYVDATRKKENCCSFTTYNAIELEGAEFEIAPNSGIHTILLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJP1</accession>
    <name>A0A5C6ZJP1_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase</fullName>
            <ecNumber evidence="2">2.5.1.145</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2 3" type="primary">lgt</name>
        <name evidence="3" type="ORF">ESY86_04595</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + L-cysteinyl-[prolipoprotein] = H(+) + S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[prolipoprotein] + sn-glycerol 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:56712"/>
            <dbReference type="Rhea" id="RHEA-COMP:14679"/>
            <dbReference type="Rhea" id="RHEA-COMP:14680"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57685"/>
            <dbReference type="ChEBI" id="CHEBI:64716"/>
            <dbReference type="ChEBI" id="CHEBI:140658"/>
            <dbReference type="EC" id="2.5.1.145"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; lipoprotein biosynthesis (diacylglyceryl transfer).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the Lgt family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.145" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00664"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008961">
        <property type="term" value="F:phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042158">
        <property type="term" value="P:lipoprotein biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01147">
        <property type="entry name" value="Lgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001640">
        <property type="entry name" value="Lgt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30589">
        <property type="entry name" value="PTHR30589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01790">
        <property type="entry name" value="LGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00544">
        <property type="entry name" value="lgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="186"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="213"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="242"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)</name>
            <dbReference type="ChEBI" id="CHEBI:64716"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="280" mass="32364" checksum="02C542E9268DAD02" modified="2019-11-13" version="1">MFALEIVWDPSKGLDLGFFMLHYYSVMWIVAFLLGLNIMKRIYKHEGQSEKSLDSLFIYSVVGIMLGARLGHVIFYQPELFTEDFFSIFLPVKFKGGFEFTGFQGLASHGAAIAMIISMYLYNKKVLHKTVLWILDRVVIPVASGAVFVRLGNFINSEIIGKPTGSDFGVVFKQLGETFPRHPAQLYEAFSYVFVFLALMYFYWKTKKSEQEGFLFGLFLVLLWTVRFFVEFMKEPQGDEYFILMGFNTGQLLSIPFILIGLYFMFVYKSKRSDVEKTRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJQ4</accession>
    <name>A0A5C6ZJQ4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Succinate dehydrogenase/fumarate reductase iron-sulfur subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_08225</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025192">
        <property type="entry name" value="Succ_DH/fum_Rdtase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13085">
        <property type="entry name" value="Fer2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13183">
        <property type="entry name" value="Fer4_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="3">
        <location>
            <begin position="151"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="246" mass="26737" checksum="666EA7874F20584C" modified="2019-11-13" version="1">MNLTLKIWRQKNAKTKGKMVDYPIKDVSPDMSFLEMLDVLNGQLITNGDEPVSFDHDCREGICGSCSLQINGEPHGPDRGVTTCQLHMRMFNDGDTIFIEPFRAKAFPVIKDLIVDRSAFDRIQQAGGFISVNTSGNTIDANTIPINKHDADDAFSAATCIGCGACVAACKNASAMLFVGAKVSQYALLPQGEIEATDRVLNMVKQMDVEGFGNCTNTGACEIECPKGISLKNIARLNVEYLKASF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJT7</accession>
    <name>A0A5C6ZJT7_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glyceraldehyde-3-phosphate dehydrogenase</fullName>
            <ecNumber evidence="8">1.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">gap</name>
        <name evidence="10" type="ORF">ESY86_10510</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.-" evidence="8"/>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020831">
        <property type="entry name" value="GlycerAld/Erythrose_P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020830">
        <property type="entry name" value="GlycerAld_3-P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020829">
        <property type="entry name" value="GlycerAld_3-P_DH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020828">
        <property type="entry name" value="GlycerAld_3-P_DH_NAD(P)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006424">
        <property type="entry name" value="Glyceraldehyde-3-P_DH_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10836">
        <property type="entry name" value="PTHR10836"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02800">
        <property type="entry name" value="Gp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00044">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000149">
        <property type="entry name" value="GAP_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00078">
        <property type="entry name" value="G3PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00846">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01534">
        <property type="entry name" value="GAPDH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00071">
        <property type="entry name" value="GAPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gp_dh_N" evidence="9">
        <location>
            <begin position="4"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glyceraldehyde 3-phosphate binding" evidence="4">
        <location>
            <begin position="150"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glyceraldehyde 3-phosphate binding" evidence="4">
        <location>
            <begin position="210"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="13"/>
            <end position="14"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="315"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Activates thiol group during catalysis" evidence="6">
        <location>
            <position position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD88919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="333" mass="36007" checksum="3E2F61D82B1FE63B" modified="2019-11-13" version="1">MANLKLGINGFGRIGRIVFRATVNRDDVDVVAINDLLDVDHLAYLLKYDSVHGRFDGTIEVKDGHLVVNGKTVRVTAEKDPKNLKWDEAGADVVAECTGIFTTMETADYHIQAGAKKVVISAPSKDVKMFVMGVNDHELTAEHKIVSNASCTTNCLAPLAKVIEDNFGLAEGLMTTIHATTASQLTVDGPTKKDFRAGRSALVNIVPASTGAAIAVGKVFPKVDGKLTGMAFRVPTVDVSVVDLTFRTEKETSLKEIKAAFKKASEGAMKGVLGYTEDKVVSQDFVSDPRSSIFDADAAIELNSRFFKVVSWYDNEFGYSNKLVDLAQKVNAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJV9</accession>
    <name>A0A5C6ZJV9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CoA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_04790</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13380">
        <property type="entry name" value="CoA_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CoA_binding" evidence="1">
        <location>
            <begin position="3"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="120" mass="13736" checksum="A11E172E06414B32" modified="2019-11-13" version="1">MSKKTLVIGASLKPQRYSNIAINRLVSYKNEVVAFGLREGTVAGIDIDTNLHAYKDVHTVTLYLNPERQKSYYDYIISLRPERVIFNPGTENPEFQNLLQQAHIPFQEACTLVMLSTNQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJY5</accession>
    <name>A0A5C6ZJY5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glucose 1-dehydrogenase</fullName>
            <ecNumber evidence="1">1.1.1.47</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_05165</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.47" evidence="1"/>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047936">
        <property type="term" value="F:glucose 1-dehydrogenase [NAD(P)] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="252" mass="27179" checksum="A8A2E708E9160403" modified="2019-11-13" version="1">MKRAEKKVVIVTGGAKGIGRETCLLLAKEGAKVAVVDILDKEGQALAEKINKSGGVSKFWHLDVSDEKEVEKVYAEVVKEFGKLDATVNNAGIAGADKPSTEVTEKEWDLVMNINVKGVFFCTKYAVPHMKKSGGGSIVNISSIYGIIGAADLPAYHASKGAVRVMSKTDAIQYAKEKIRVNSVHPGFIWTPLVEELGKDKPGFREQLDSLHPIGHIGEAIDIAYGILYLISDESKFTTGSELVIDGGYTAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK25</accession>
    <name>A0A5C6ZK25_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Mechanosensitive ion channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_10555</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD89009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071470">
        <property type="term" value="P:cellular response to osmotic stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030192">
        <property type="entry name" value="YbdG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30414">
        <property type="entry name" value="PTHR30414"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD89009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="415" mass="47693" checksum="CF73668EA2943664" modified="2019-11-13" version="1">MTQIQCFFYDHYVNIGVSEVTASYLNMFTLLVILVAIIFATDRLARKFLIRFFTRFSARTATNFDNLLVNHRAPTNIAHLVPLLITIKLFPTVFYDFPQFESFIVVLLKIYGIVLTIWIIRSILNTFESYFKTIPRFRDKPIDSYIQVVMLFLWIVGVASVLAVLIDLSFIKFFTTLGAASAVLLLIFKDTILGFVASINVAINDSVRIGDWITMENFGADGEVIEINLSTVQVQNFDMTITNIPTYALITDSFKNWRGMQSSGGRRIKRSILLRAKSVKYLTNDHIERLKKIEIVSKYLENKQLDIENFNSTKNVDKSVLINGRNLTNIGVFRKYMQTYVENHSAVNKDMTIMVRQLAPTPQGFPLEIYCFSSDKRWENYEYVMADIFDHAIAAVPYFDLEIFEFSTDLKALGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK48</accession>
    <name>A0A5C6ZK48_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase family 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_09775</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="9"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="341" mass="39451" checksum="C1DCD625DA141016" modified="2019-11-13" version="1">MREVKPKVTVLMPVYNGDKYLRAAIDSVLAQTFRDFEFLIINDGSTDDTQNIIDSYTDSRIKCHKQTNQGVAKSLNNGLKLATGEFIWRHDADDICLPEQLQTQLDFLKTHANFALVSTQIAFMSDRGRIAYDYKQPKDAFFNGQTFMKVERSQFNPFSPITHATVLIKKKVFDTIGVYRTEFKTSEDTDLWLRVIEHFDAAVLHYCSYFVRLNSTSATQIYKKTNTFYRDLAFQFADERTQKGTDVLLRGEPMPQPTEEVLEFKSKPLSNSKKGTNFRKDLLNFQYKVMLNAKDYQNVFKIIKISLKDGWKLSKTWRAILFPMLGDDVINIGVKLKSFLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKI2</accession>
    <name>A0A5C6ZKI2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">1,2-phenylacetyl-CoA epoxidase subunit B</fullName>
            <ecNumber evidence="1">1.14.13.149</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_01945</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.13.149" evidence="1"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097266">
        <property type="term" value="F:phenylacetyl-CoA 1,2-epoxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.520">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009359">
        <property type="entry name" value="PaaB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038693">
        <property type="entry name" value="PaaB_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06243">
        <property type="entry name" value="PaaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF030200">
        <property type="entry name" value="PaaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02157">
        <property type="entry name" value="PA_CoA_Oxy2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="96" mass="11228" checksum="E1D808947CF82643" modified="2019-11-13" version="1">MSQKKNWPLWEIFVRSKNGLEHRHFGSLHAADAEMAMENARDVYTRRNEGVSIWVVESCNITASNPDHNGELFEPAQDKVYRHPTFYDLPDEVKHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKL7</accession>
    <name>A0A5C6ZKL7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06750</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="208" mass="22827" checksum="65AE16F458E35023" modified="2019-11-13" version="1">MAEIKIKKKTSIWPWIVAILAILAILYFVFIYSDDDAEADDVSDNDIEMVTDDVDNTANDAKNVFSETAISKIAEFKTHIAEGAEMGLEHEYSHAALDKLIDATQAVANTLNVDIAADLETARSIAGSVEDDTYAVDHADNIKNAGNTIVKVLKKIQMQRFPNLDESCTELQNSVMAIAPGTQTLEQKAAVKNFFDQAGELLTNMKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKP1</accession>
    <name>A0A5C6ZKP1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4268 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025364">
        <property type="entry name" value="DUF4268"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14088">
        <property type="entry name" value="DUF4268"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4268" evidence="1">
        <location>
            <begin position="10"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="142" mass="17249" checksum="D2E273DA64421317" modified="2019-11-13" version="1">MFSKEESRQLRQEFWTSFGKSFPRKWILYDTKIKGLAFKFHFDTKSAMVALDVEDDLEQRITIWERLESLKSILKMDYLPNAIFAEEFILKNGKEISRIYLPLEQKVSIHNKNTWREVMVFFNDEMLKFELFFEDFEDVLRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKZ9</accession>
    <name>A0A5C6ZKZ9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">SusC/RagA family TonB-linked outer membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_01725</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023996">
        <property type="entry name" value="TonB-dep_OMP_SusC/RagA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023997">
        <property type="entry name" value="TonB-dep_OMP_SusC/RagA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04056">
        <property type="entry name" value="OMP_RagA_SusC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04057">
        <property type="entry name" value="SusC_RagA_signa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022825250" evidence="5">
        <location>
            <begin position="23"/>
            <end position="1084"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="7">
        <location>
            <begin position="115"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="6">
        <location>
            <begin position="459"/>
            <end position="1082"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD90709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1084" mass="118239" checksum="ADB4B36B08DBDF3E" modified="2019-11-13" version="1">MKLKLTWLMTLFMACVMSFSYAQEKTVTGTVTTSEDGLPLPGASVIVKGTTRGVQTDFDGRYSITANTGDVLVFSYVGTKTAEITMGASNVYDVALEFDNALEEVVVVGYSSTTKEAFTGTASIVDIEEIENKIVSNVTQALRGEIAGVNIVQRSGAPGSTAEVRIRGFGSVNGNQLPLYVVDGAPLTNNSREEVGINLNAINPADIESMVVLKDAAATSIYGSRGANGVILITTKQGKAGTSRISADFTTSVTSLVLPQYDIIESPEEYVEISWRALRNNATLNGLSNPAQYASSNIYSADGSGVGINSLYNIWNVPGNQLINPATGRFDPNVQRRFTPTTFGDAAFGTGKRTEANVQFSGGDEKTKFAGSIGYLDDEGYALNSRYTRYSTRLNLEHKPTEWLTVGANMAYTGARSRNSSDAEGDTGSSGNIFALVNTTPAIYDVFLRDQDGSLVSDPIFGGSQYDYGLGRRAWTNTNAVGVATYDLSQSDITTLLGNFNVGVKMTDWLNFEMRYSGQFQSAKNASRGNSFYGGAAATGGNLFLDDDLSTNQNFLQLLRYNQSFGQHSVEFFVAHESTEDRFKTIAAGSQTAILPNTLDLNQYTFPFGRASSFTQGWTLDSYFSQLNYNYDNKYYVTGSIRRDGSSRFKNNKWGTFGSVGLGWIVTKEDFMSDIRFLDFLKLKASYGAIGDQGTSLQYGYQIQLINSTSDGSYSFTESATLANPDLTWETSNIAQVGFESSWLGNRLNVDVDLYDKRTTNLFFTENLFPSIGSSLFQYNDGELTNRGIEFNVVGKIIENENLRLSVNVNGEIFDNEITRMPTGRGQSEPLVFDDNNNLAKGKSIFDWFMREWAGVDPGNGAALWNLYYDDINNDGIFNAGDTQISNLFTYQDENPGAQIGRTVTDTYANATQRFVGKSAIPKIRGGFRLNLGVKNFDVSAQFSYSLGGYTYDAGYSVLMGNDLVGADNFHTDIRNAWQQPGDITDVPRTSAQFGTDAQQNAFSTRFLTRSDFFALNNINLGYTLPKAAIDAIGLSTFRLFVAGDNLMMLSARRGLNPTTAIATTNSGAYTPVTTFSLGAKVEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL02</accession>
    <name>A0A5C6ZL02_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="84"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="122" mass="14053" checksum="2F75A26005F15408" modified="2019-11-13" version="1">MNAEKNVESHGMFQNKTSPKICVIRRKQTEACEALKHADFADERRENVESHGMFQNKTSPKICGICGKQTEACEALKPADFANERRENVESHGMLQNKLREDLRHPRETNRSLRSTKARKSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL06</accession>
    <name>A0A5C6ZL06_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidylprolyl isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_06555</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000297">
        <property type="entry name" value="PPIase_PpiC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027304">
        <property type="entry name" value="Trigger_fact/SurA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00639">
        <property type="entry name" value="Rotamase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109998">
        <property type="entry name" value="SSF109998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50198">
        <property type="entry name" value="PPIC_PPIASE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0697">Rotamase</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022830997" evidence="2">
        <location>
            <begin position="31"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="domain" description="PpiC" evidence="3">
        <location>
            <begin position="203"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="PpiC" evidence="3">
        <location>
            <begin position="308"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="484" mass="55552" checksum="7C31D73E0C7D4FEE" modified="2019-11-13" version="1">MLLKTNDLRFTIKTMVLTALISAFSVHTYAQEIIEDETDNSGKVLDSTQTAARQKVDGVAAVVGDFVILDSDIDKEYMQLQARGVSIARFTRCELFGKLLEDKLYAHHAIQDSITVNELEVRSMVEQQINSILEQKGGSMAELLEFYSKDNEQSLREEMFEINKNGKLVADMQRKIVADLEVTPEEVREYFNDIPKDSLPTFGTELKVAQIVIIPEVSEEAKKAVIRKLKDFKADVIENGASFTTKAVFYSDDVAARSKGGLYTLNKKRPQMVKEFRDVAFSLQEGEISEPFESDFGYHIVLLEKIRGQEYDVRHILLRPELSDEAIIEAKDEINKIRERIVSGDLTFNAAAREFSDETETKNDGGQLTNPMTQDFNFELTNMDPELYGQIQDLKDGEVSLVLQDQDRVNRIKFKIMSVTDRINDHKADFAKDYLKIKNLTEQEKQYETIKKWQDEKINDTYVKISEDYRSCKFDGNWLKLDKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL99</accession>
    <name>A0A5C6ZL99_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">4'-phosphopantetheinyl transferase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_08515</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008897">
        <property type="term" value="F:holo-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008278">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01648">
        <property type="entry name" value="ACPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="SSF56214"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACPS" evidence="2">
        <location>
            <begin position="104"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="208" mass="24411" checksum="1EBE4BB979DB6BE3" modified="2019-11-13" version="1">MPLYKTIQPNSQTTVKIWKIEESYTDLMQPLDLKPDSLERVLGMKSELHQRGFLSVRHLLREFGYTDQDLYYDAHGKPHLKDGKHISITHSFTFSGVIISASEVGIDIEMQREKIAIIAKKFVDYEFNYLSETDKDYIQKLTVVWGIKESLYKLFATPGMLFRQHFLVIPFMLKDGETVAWIDYQDRKYKYDTYFLEFEGFTCAYALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLR1</accession>
    <name>A0A5C6ZLR1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PadR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_01225</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005149">
        <property type="entry name" value="Tscrpt_reg_PadR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03551">
        <property type="entry name" value="PadR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PadR" evidence="1">
        <location>
            <begin position="19"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="110" mass="12624" checksum="ABB65A57C676A560" modified="2019-11-13" version="1">MKIENTKAQMRKGVLEYCILSVLRDEDAYVAEILETLKDAKMLVVEGTIYPLLTRLKNAGLLNYRWEESTSGPPRKYYGLTNTGKLFLSELNSTWTELQNAVNLVTRHNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLS4</accession>
    <name>A0A5C6ZLS4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_04510</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="288" mass="34588" checksum="0307FBAB36F5A429" modified="2019-11-13" version="1">MKKIHVGFLLSYDYDKLKKSIPPVYKSADRIFIAMDKELRTWSGEYFTLDPSFFEWLKDFDSENKIEIYEDDFYVPELKAIENDNREREMLSKKMGIGNWLVQVDSDEYFFNFESFVKDLRKYDKYLDNPEKKNIQIAAFLINLYKYSDDGILYVKAPTRGVMATNYPNYKVARNTRKRIVYTQNLLLHESIARTEEELLLKFENWGHNIDIKDKDAFMEKWRTTNKSNYEQREDFFYIEPEKWKHLDYAQGKTLEEIAGNMDLKAIMPSKTFIAGKNFGQWFKFLFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLX3</accession>
    <name>A0A5C6ZLX3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_06950</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004316">
        <property type="entry name" value="SWEET_sugar_transpr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03083">
        <property type="entry name" value="MtN3_slv"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD89930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="88" mass="9781" checksum="1AD9A6EB9BC78741" modified="2019-11-13" version="1">MLAEDLIGILAGVFTTLAVLPQIIKALQTRKVEDVSPYMFFILCLGVGLWTVYGIFKMDWPIILTNGISFILNSLMLGIIITQKQHGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLX9</accession>
    <name>A0A5C6ZLX9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acyl-CoA--6-aminopenicillanic acid acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_01620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005079">
        <property type="entry name" value="Peptidase_C45"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03417">
        <property type="entry name" value="AAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="338"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="419" mass="47021" checksum="9447E334A687CAFA" modified="2019-11-13" version="1">MQLHFTAVSEPGVPGKKWQKLYNTHWEAYRTWLISKGNAYEPDLKTSQEALKKYMPEMWPTYERLCKLAKADDVAARFLTGFQPPAYISACSNAVLSGDEIQLVRNYDYHPSLMEGTQLMSAWNGKKVIATSDCLIGAVDGMNEDGLAISLTFGGRKEVGVGFGIPFILRYVLEFCSNVEEAVAALVRIPSHMSYNVTVVDKTGLFKTVQLAPDKEPVVTDAAFTTNYQGTVDWPENAAFNKTLERSAFLENMLAKKGLTASAIADAFLQKPLYNTKFKQGFGTLFTAVYQPARGVVEMRWPSEKVTQTFEGFQEQYKLIQFDEPALASMQDTAWASAPSETPEMTPQEALAPSTSKADWQKTVNETLVNAMAHSPNAKEREKPQLIREDIVHRGDISWEILADYWANVGKSYWEKWQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM22</accession>
    <name>A0A5C6ZM22_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03045</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="10"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="170" mass="19314" checksum="68C0F963533A6323" modified="2019-11-13" version="1">MTAKATYPKSFSHIGITVPNIKAAVKFYEEVMGWYIIMKPSTVKKEKDTAIGQMCIDVFGDDWEAFEIAHMSTSDGIGVELFSFPHGKKEAPEFNPFNTGLFHFCIQDPNIEELVDKIVSSGGKQRMPIRAYYPNDKPFKMCYVEDPFGIVFEIYTHSYELTYSSGAYSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMB6</accession>
    <name>A0A5C6ZMB6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD family phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_01105</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="205" mass="23946" checksum="309C869A1C9315E9" modified="2019-11-13" version="1">MPTIKTIIFDFGAVFIDLNKEVAHQNALALFELDELHDELVSMNTLYEQGLMSTEEFLDFYTANFPKLSKPQLIDTWNSMLGHFPEKRLNFIKSLASEANYKLILLSNTNDLHINWIIDNVPFFEDFKKQFDAFYLSHEIQLRKPNADIYEFVLKQNKLTPEECLFIDDTKANTDAAANLGIHIWNIDETQEDVTDLFRIKKDLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMD1</accession>
    <name>A0A5C6ZMD1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Peptide methionine sulfoxide reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_03595</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="84" mass="9525" checksum="6677F6362F7F8E7C" modified="2019-11-13" version="1">MGLLQKIRALAVGYSKVVYQEKKYAVTRSDFNNGKSIKLVAEELGGSDFISLNYYITTSKEILKPCEMPVVKVTDFLNNYKLIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMH9</accession>
    <name>A0A5C6ZMH9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PorT family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_00755</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025665">
        <property type="entry name" value="OMP_b-brl_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13568">
        <property type="entry name" value="OMP_b-brl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022807468" evidence="1">
        <location>
            <begin position="21"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="OMP_b-brl_2" evidence="2">
        <location>
            <begin position="20"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD91152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="210" mass="22726" checksum="A5B8A59F5689F670" modified="2019-11-13" version="1">MKKLMLLTSMLVFGLAISNAQEIKFGAKAGVNFASLGGDLKDVDGRTSFHIGAVAEIVISQQFSFQPELVYSSQGFKVNGTDYTIGVAIDVEQTLKLEYINLPLMAKFYVAEQFAIEAGPQIGFLVAAKSKIESTSNGTSESNTEDVKDFYKGIDFGLGAGVSYKLENGLFFGARYNLGLSNISENGNAEIADDFETQNNVIQVSVGYFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMP2</accession>
    <name>A0A5C6ZMP2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleotide excision repair endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06830</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035901">
        <property type="entry name" value="GIY-YIG_endonuc_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01541">
        <property type="entry name" value="GIY-YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00465">
        <property type="entry name" value="GIYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82771">
        <property type="entry name" value="SSF82771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GIY-YIG" evidence="1">
        <location>
            <begin position="177"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="435" mass="50069" checksum="EA032D97845D3C48" modified="2019-11-13" version="1">MTSIYIQTLSTGKKAEIPYRISLKNDEHPQAVRSFDFRPEVSVPKRIYEQHNLDRMALLAAPPFCDIADELIELLQEQALVFSEVRQFKLLKSQFKAIGYNFNVRPKFVWHRADKDTENAVELVLRDARNLCAQSLEYAEAFLEVMQQFLCNRNMDSPAPKPTAALTNRLDLSRYKMAAGVYYFLNPFEDVIYVGKAKNIRKRLQSHFSTASLSNINYAEVNAINVDYSGNDLMAQLMESANIKALKPIYNTQQVKDPAPYIINKGKTASGINKLQITRKEIVNNMPERYFNRTSVKQSLEQFCAEHQLCRKHCALERVKGPCSNHTKKHQACVCAGTESTEDYNTRFERAFEQFQNRKSRVIYKLKGRHTEEDAFIYMVNGIYEGYGFIDKTEIIANENDILGHLTPQTNNYDTSRILSDLSRKVKAEHIFSLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMR6</accession>
    <name>A0A5C6ZMR6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Restriction endonuclease subunit S</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_04380</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-I restriction system S methylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.220.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000055">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044946">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01420">
        <property type="entry name" value="Methylase_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0680">Restriction system</keyword>
    <feature type="domain" description="Methylase_S" evidence="4">
        <location>
            <begin position="22"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="195" mass="21831" checksum="38E958384DBB7D6D" modified="2019-11-13" version="1">MQNKSVVLKSILAYNGLSSGHSFRDKIKHTHNGSLRVIQLKDFEENYTVIGNDCVLVDGEKIKTKNYLENGDVLFISKGANNFAVSYMGFDDIPTIASSALFVLKINKNLANPDFVAWYINQSKVQNYFKTNEAGTYTTSINKATIEHAPIILPSLEMQTKIAKIANLHNQELVLNNKIIELKNKLTTAQLLNIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN64</accession>
    <name>A0A5C6ZN64_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_01525</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="SSF50630"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022660864" evidence="1">
        <location>
            <begin position="24"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="288" mass="32435" checksum="214F8A432D8DFF24" modified="2019-11-13" version="1">MKNLKPVVFALILLLSFSCSVTKNQKKGTVLPERFNYETEFTTAKTVMIIPSKINGVSKNFYFDTGAQYSMIQRDSLIGKTEYATGASKRVMKVGTEFIASFKIGTIDFRNTIAMNGDMEGLKEQIPNFGGIIGQPIINKANWLIDYPNKKLQISNETLVDETFETIKIKREDGSPYTYISINGIEYKVVIDFGSSSEFNLPKESKLAKQLLQLYDFDDNERERYTLGGLQTIQEKVGIVPLIKLGNIAFENVSTTINVSSQPRIGIGFFKDCEIYIDNIGNSYKIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN95</accession>
    <name>A0A5C6ZN95_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF427 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03605</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.150.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007361">
        <property type="entry name" value="DUF427"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038694">
        <property type="entry name" value="DUF427_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04248">
        <property type="entry name" value="NTP_transf_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NTP_transf_9" evidence="1">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="93" mass="10744" checksum="FC83C0E4AAAF72C4" modified="2019-11-13" version="1">MKAIWNNEVIAESDETVVVENNHYFPQDSIKTEFFKPSQTHSSCPWKGKASYYSLEVDGKENKDAAWYYPEASEKAKAIKNHVAFWKGVEIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNV2</accession>
    <name>A0A5C6ZNV2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PA2169 family four-helix-bundle protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00065</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011971">
        <property type="entry name" value="CHP02284"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019052">
        <property type="entry name" value="DUF2383"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016920">
        <property type="entry name" value="UCP029477"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09537">
        <property type="entry name" value="DUF2383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029477">
        <property type="entry name" value="UCP029477"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02284">
        <property type="entry name" value="TIGR02284"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2383" evidence="1">
        <location>
            <begin position="16"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="158" mass="17926" checksum="D3522C748438FFFA" modified="2019-11-13" version="1">MKTTAEEAREKSHKETVKVLQKILEKNYDAEKGYTKAMKGATTPTLKAFLKQQAAQRSRFANTIDNRLRQLNEKPKEGGSTAGTMHRAWIDIKSSLTGNDDEAVLKEVIRGEKASVEEYQDVLKKHKFVPEITQELQTQLEDIQATLNEVTHIEDLKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPJ0</accession>
    <name>A0A5C6ZPJ0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">GH3 auxin-responsive promoter family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_02930</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004993">
        <property type="entry name" value="GH3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31901">
        <property type="entry name" value="PTHR31901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03321">
        <property type="entry name" value="GH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="507" mass="58371" checksum="2C4A66B7E1D5C29D" modified="2019-11-13" version="1">MPIPLVNSIASWFLKKRFHQIDLFLKYPNEVQNELLFHLLAKAKDTEIGKQYHFDSIGNYSTFAERVPISCYEDYQDLIERSRRGEHNIFWPHPIKWFAKSSGTTNAKSKFIPVSSESLEDCHYAASKDLLCLYLNNNPDSQLFTGKSLRLGGSKELYKENGTAFGDLSAILIDNMPFWAEYSSTPSNKVSLMSNWEHKMHAIVEETRYENVTSLAGVPSWMLVLLNKVLDDTGRDNLFDIWPNLEVYFHGGVSFVPYVDQYKAILPKQDFRYYEIYNASEGFFAIQDQNSSSELLLMLDYGIFYEFIDMSTYGSCQPKVIPLSAVELHKNYAVIITTNAGLWRYKIGDTVRFTSIDPYRIKVSGRTKHHINAFGEELIIENAENALQQVCAITNAEIVEYTAAPIFMSGRAKGSHEWLIEFKTLPEDIQEFNILLDTTLKSLNSDYEAKRLNDMTLNMPTIHIARERLFYDWLKRHDKLGGQHKIPRLSNSREYIDELLGLNVSVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPS5</accession>
    <name>A0A5C6ZPS5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Tungsten formylmethanofuran dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_01850</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016624">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transket_pyr" evidence="4">
        <location>
            <begin position="335"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="302"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="671" mass="74811" checksum="E3E96FDFAC94A3B9" modified="2019-11-13" version="1">MTDLYEENFKEVSKYVHATSRGHEAIQTALGMQLLPQDYAYPYYRDDAMLLSFGCTPYDLMLQLLAKKDDPFSAGRTYYSHPSLRDDDKPKIPHQSSATGMQAIPATGAAMGLKYKETLSEGKKPPFNVPPLGARGIIVCSLGDASVTEGEIAEAFQMAALKQLPILYLIQDNDWDISANAEETRAQNAFEYAKGFHGLEAITIDGANFIESYEAIEKVIKTMREERRPFLVHAKVPLLNHHTSGVRMEWYRDDLEEAKSRDPYPVLKQQLLDNGISSEEIERIETDAKRKVETAFMLSKKQDDPTPEDLFTHDFAPTPITEEKGERAPKGAEKVVMVDCALFAVEELMKKHPECLLYGQDVGGRLGGVFREAATLAQKFGDERVFNTPIMEAFIVGSTVGMSAVGLKPIVEVQFADYIWPGLNQLFTEVSRSCYLSNGKWPVSMILRVPIGAYGSGGPYHSSSIESIITNIRGIKIVYPSNGADLKGLMKAAYYDPNPVVILEHKGLYWSKVPGTKGATSIEPAEDYVLPLGKAWVLQEIWKQEEVETMTIVTYGMGVHWAYNASGELDMRKQIEIIDLRTLFPLDEKTIMASVKKTGKCLVVTEEPSDNSFARALAGKIQEECFRYLDAPVMTIGSENMPAIPLNSVLEETMIPSTEKVKAKIRTLMNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZR22</accession>
    <name>A0A5C6ZR22_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Four helix bundle protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_01490</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16377">
        <property type="entry name" value="23S_rRNA_IVP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012657">
        <property type="entry name" value="23S_rRNA-intervening_sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036583">
        <property type="entry name" value="23S_rRNA_IVS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38471">
        <property type="entry name" value="PTHR38471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05635">
        <property type="entry name" value="23S_rRNA_IVP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158446">
        <property type="entry name" value="SSF158446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02436">
        <property type="entry name" value="TIGR02436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="118" mass="13827" checksum="F11F41C1DAEC7C3C" modified="2019-11-13" version="1">MEQFKFEKLIIWQKAMDLGEDIDKMADAFPLKEKFNLTSQIRRASDSIALNISEGSIGQSNPEQFKFMGYSIRSLAEVVTCLFKAKRRLYITDEQFQPYYLQAHTLMNMMIAFRNNLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZR48</accession>
    <name>A0A5C6ZR48_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Four-helix bundle copper-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_00275</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005560">
        <property type="entry name" value="DUF326"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03860">
        <property type="entry name" value="DUF326"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="105" mass="11416" checksum="F4EF02A68C3A7D27" modified="2019-11-13" version="1">MKNEYKSCIQRCQDCLVECQNCLMKMAGMESMNDCPKCCALCIDACLACIKFLSADSEFSAQYCKICAEVCAWCAIQCEAHDHDHCQACAASCRACAEACTALAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZRX5</accession>
    <name>A0A5C6ZRX5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">YtxH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_01290</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024623">
        <property type="entry name" value="YtxH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12732">
        <property type="entry name" value="YtxH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="82"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD91340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="116" mass="12531" checksum="EAD9000083B42394" modified="2019-11-13" version="1">MGKESSALLGILAGTAIGATLGILFAPDKGVNTRNKIAEETAHAKDKITERATHLKDNVVNTWASSKATLDEKVESIVTDASHKADDVISTLESKLSQLKEKNKNLQKDKNFQKTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6Z9F2</accession>
    <name>A0A5C6Z9F2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">IS3 family transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20725</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000110">
        <property type="protein sequence ID" value="TXD85922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025948">
        <property type="entry name" value="HTH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002514">
        <property type="entry name" value="Transposase_8"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13276">
        <property type="entry name" value="HTH_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01527">
        <property type="entry name" value="HTH_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13683">
        <property type="entry name" value="rve_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="215"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD85922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="377" mass="44756" checksum="B09765C8AB297E7D" modified="2019-11-13" version="1" fragment="single">MRRNFDNEFKTTVVELLQAGKSVRELCEEYSLQDGTIRRWRREYGQKNGDLSKKRVPTASEVELSRLKKELRETRLERDIFKKGGEHLFQERQLKYGFVFNNKESYPVEKMCHCLKISKNAYYNWLKNKDVVNIDTCKIHLMNRIADIFEDSKEVYGSHRVQKMLEREDLFYSRSYVAVLMRKMGLRSILKRKFVVTTKSDHSYPIAENVLNRDFDSQAIGEKWVSDITYIRVKDGWNYLTTIMDLADRKIVGWSLSEDMTVENTVWRAWTSAIGTRKTRPNFIFHSDRGVQYAANKITRMMRENIRMSQSMSRKGNCWDNAVAESLFKTIKYECTNRYRFASSEQLHACLVEYISWYNTKRIHSTLGYRTPLEMQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZA81</accession>
    <name>A0A5C6ZA81_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">IS110 family transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_20130</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000058">
        <property type="protein sequence ID" value="TXD86457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003346">
        <property type="entry name" value="Transposase_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002525">
        <property type="entry name" value="Transposase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01548">
        <property type="entry name" value="DEDD_Tnp_IS110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02371">
        <property type="entry name" value="Transposase_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEDD_Tnp_IS110" evidence="2">
        <location>
            <begin position="9"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="158"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="323" mass="36408" checksum="232165AC3F37FD2F" modified="2019-11-13" version="1">MNKDIKYFGLDISHLVFDVTDSDGNYYQFKNGLSGFKKFAKLLGSQSHCVMEATGYYHYQLAYYLLEDGIKVSVENPLSVKRFIQMRLSRIKTDKSDSKLICDYAQQVELKLWKGNSKEVQECLQITRALSVYTKQGTMLKNKLHGESVLGEPSKAVVRSLKRSLKQLEKEMNTLEGRLLVLVKESHQDLFTRLKTIPGIGRKTAIMLIVLTGGFERFSSSGELCSYAGLTPVIRQSGSSIKGRPRISKMGNQKLRNLLFMCSFTACKHNKACRDLYERIVAKGKSKKLALIAVCNKLLKQAFAIAKSGLIFDNEYKSALAKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZA87</accession>
    <name>A0A5C6ZA87_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">IS1595 family transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">ESY86_08070</name>
        <name evidence="10" type="ORF">ESY86_08965</name>
        <name evidence="9" type="ORF">ESY86_09680</name>
        <name evidence="8" type="ORF">ESY86_11550</name>
        <name evidence="7" type="ORF">ESY86_17960</name>
        <name evidence="6" type="ORF">ESY86_18115</name>
        <name evidence="5" type="ORF">ESY86_18490</name>
        <name evidence="4" type="ORF">ESY86_20085</name>
        <name evidence="3" type="ORF">ESY86_20185</name>
        <name evidence="2" type="ORF">ESY86_20250</name>
        <name evidence="1" type="ORF">ESY86_20755</name>
    </gene>
    <organism evidence="4 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000118">
        <property type="protein sequence ID" value="TXD85863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="VORO01000061">
        <property type="protein sequence ID" value="TXD86429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="VORO01000060">
        <property type="protein sequence ID" value="TXD86436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="VORO01000057">
        <property type="protein sequence ID" value="TXD86478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="VORO01000032">
        <property type="protein sequence ID" value="TXD86984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="VORO01000029">
        <property type="protein sequence ID" value="TXD87141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="VORO01000028">
        <property type="protein sequence ID" value="TXD87200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD85863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD86478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD86984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD87141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD87200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD88602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD89299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD89500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD89727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="37" mass="4522" checksum="F0D119B87D345FF2" modified="2019-11-13" version="1" fragment="single">KYLQLYLNEFVYKLNRRYFGERIFDRLVIASITANGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAT1</accession>
    <name>A0A5C6ZAT1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_20420</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000071">
        <property type="protein sequence ID" value="TXD86301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="373" mass="41881" checksum="8073E8D534BDA6D8" modified="2019-11-13" version="1">MKKCTSNSSTVLAKNRSLKFLTIFSFFVLYFNSGFSQTVEGTVSDNLGMLLTAKIVFIASNKKNVVSEYCLALNGKFSYNLKKMYSEGLILKATATGYSAFETTITSTNKKDTLVYKITLIKEKIELLKEVIVKGKKKPFLVKKDTTVFRVDSYKDGTERKVEDLLKNIPGIDVNETNGTIKYRGKLIETVTIEGDNLFDYNYTIGTKNINIDLVDEIEAIENYSENKLLKGIEYSDKIALNLKLKKNITDITGSIDLGIGDKPDAKETPINTSVNLLAINTSLKSFAVSSYNNVGANLSPFDYYGNQINLEQLKEEDLYAQKVIPELSLPQVTNKNLSNINHQFFNNFNGIFNLNKKLLYIRLVSISCNACY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZB03</accession>
    <name>A0A5C6ZB03_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19480</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000041">
        <property type="protein sequence ID" value="TXD86723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046219">
        <property type="entry name" value="DUF6252"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19765">
        <property type="entry name" value="DUF6252"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="181" mass="19941" checksum="6DAA67AF1D0ECD47" modified="2019-11-13" version="1">MCLAILIIFPLWGLGGCNNDDDNNNNDTLPPATQIGANTVGCLVNGEVFLPRSEGINPTVVVNYEFFQGEFFFGLTFKDQRGSIDEIVSIGTGFISLEENITYVLDKNSLDDGDYIGGGGAYRPSTLDEGEYYTTSLVTGELTITRVDLSNSIISGIFWFDAINAENEIVEIREGRFDFEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZB87</accession>
    <name>A0A5C6ZB87_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">IS4 family transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_20690</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000104">
        <property type="protein sequence ID" value="TXD85976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1" evidence="2">
        <location>
            <begin position="109"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="404"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD85976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="430" mass="50002" checksum="14F5AC315CE6478C" modified="2019-11-13" version="1">MFEKVRAEIFGNGLKTEFKVSKEDFTRNRKQRFPILLLFMLNFLKKSLSLEIENFTSLLKVGPNAKFTKSAFVQARKKVRPEVFDRLSQVLLNEFYTDNEPAIKLWKGFRLLAVDGTRITLPITAELKEIYGETKNQSSTVLVQARCSVIYDVLNKYVLDGALEPLKRGERDLALSHLGHCNSDDLMIYDRGYPSYDFIYQHINRDFDYLMRAKTSFSGLVKDFEESRKKSLVVSIYPGKNAKLSDKEYTKNSPIKVRLIRIDLGKGNVEILMTSLLDSNVHPTSQFKELYFKRWGVETFYDELKNKLRIEHFSGYSNQSILQDFKAALFVSNVQTLIVSELEEDLKESNRDKKYDYKVNTNISYGLLKDRVVTLFLDKKPTGIDIVEELKTLYKSHLVPIRTNRKSERNPDKYRSRIKPKITKNQKDGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBA7</accession>
    <name>A0A5C6ZBA7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000036">
        <property type="protein sequence ID" value="TXD86864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="20"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="230" mass="26576" checksum="E5A7F202F41463E3" modified="2019-11-13" version="1">MKFQQIIIIFCSIIILTSCESDVERNKRLAQEEVQRIELETKLKKEADELAFQQEQERLEIEKQEEAERIEREITLKKEREEKAIYNKYINNSLNTGSTPYSYCFGSNKPCSERGCAGISVKTPYNSDVMVTIKKDDKVFRHTFIKAGDTYKFQFPNGTYQAFFYYGKGWNPNKIIKKVDCGILKGGFIANESFSKDKPQNLTNAELSYELILQEDGNFSTKPSNSDEAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBF0</accession>
    <name>A0A5C6ZBF0_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Oligopeptidase A</fullName>
            <ecNumber evidence="8">3.4.24.70</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">ESY86_17395</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>Hydrolysis of oligopeptides, with broad specificity. Gly or Ala commonly occur as P1 or P1' residues, but more distant residues are also important, as is shown by the fact that Z-Gly-Pro-Gly-|-Gly-Pro-Ala is cleaved, but not Z-(Gly)(5).</text>
            <dbReference type="EC" id="3.4.24.70"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the peptidase M3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.70" evidence="8"/>
    <dbReference type="EMBL" id="VORO01000026">
        <property type="protein sequence ID" value="TXD87335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06456">
        <property type="entry name" value="M3A_DCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034005">
        <property type="entry name" value="M3A_DCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024077">
        <property type="entry name" value="Neurolysin/TOP_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024080">
        <property type="entry name" value="Neurolysin/TOP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045666">
        <property type="entry name" value="OpdA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045090">
        <property type="entry name" value="Pept_M3A_M3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001567">
        <property type="entry name" value="Pept_M3A_M3B_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43660">
        <property type="entry name" value="PTHR43660"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01432">
        <property type="entry name" value="Peptidase_M3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19310">
        <property type="entry name" value="TOP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 9" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="TOP_N" evidence="11">
        <location>
            <begin position="76"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M3" evidence="10">
        <location>
            <begin position="261"/>
            <end position="709"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00026100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF19310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TXD87335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="716" mass="81905" checksum="E6840E976328049E" modified="2019-11-13" version="1">MIDKAIKTTLLCSIVLITGCKNDKNSEEKMAVNDSKNILLQEWTGPYEGVPAFDEMQVQDVKEAMKKGMVLGLKDIDSIANNPEPATFENTIVAMEGSAEALNRIFTYYGIFSSNTSSPEFRDIQTELAPKLSEYQSKISQNEKLFQRIKTVYEASQKDTLPADQQRVVDLTYKQFEMNGANLDAEKKKRYAEINKELSKLYTKFSNNILHDEENYVTYLNKNQLGGLSESFTKSAAKISSDKGQDEKYAITNTRSSIDPFLTYSTERELRKIVWTNYYNRGDNADAYDNNELIAEILKLRKERVGLMGYDNYAEWRLQDRMAKTPENAMDLMMAVWPAAIARVDEEVADMQAIADANGDNLKIEAWDYRYYAEKVRQKKYDLDSDEVKQYLQLDNLTEALFYVAGRLFNYKFTPVPNGQVPVFHPDVKVWEVADKDSGKLIGLWYLDPYAREGKRSGAWATTYRSYTSYKGEENVLASNNSNFVKPAPGEPVLISWDDATTFFHEFGHALHFFSSNVKYPTLNGGVRDYTEFQSQLLERWLSTDEVINNYLIHHETGEPIPASLVVKIKNASKFNQGFGTTEYLASALMDMKLHLADPSNIDIDKFERETLKELQMPEELPMRHRTPQFGHVFSGEGYATAYYGYMWADVLTADASEAFMEAPDGFYDKAMADKLVKYLFAPRNSMDPAEAYRLFRGRDAKIEALMRDRGFHVSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC33</accession>
    <name>A0A5C6ZC33_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000047">
        <property type="protein sequence ID" value="TXD86609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008571">
        <property type="entry name" value="HerA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002789">
        <property type="entry name" value="HerA_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42957">
        <property type="entry name" value="PTHR42957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01935">
        <property type="entry name" value="DUF87"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF87" evidence="1">
        <location>
            <begin position="147"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="582" mass="65023" checksum="D39E68338DEECB4E" modified="2019-11-13" version="1">MAIFTFEESATIGTVFSVDTATIIVKVDELDKLRKLQVNHLIAVKSSKAGQHLIGIINRITRKVSDDENPVTEDLGISNFLLTENIIKVNLIGTLIDKHGEKENVFKRTLDTVPEIEANCFPIDGENITKFMRTISSQENYAVPLSLGKYSIDENAEAFLDGDKLFQRHAVIVGSTGSGKSWCVAKLVEQIAKLPMANSILFDIHGEYSGEGFKAEGIQHLKIANPSDLGKKGNLENNVLMLPYWLLTYEEMLAMLLDRSDSNAPNQAMIFSKTVFNEKIKFLESIGDTTFKDSITIDSPIPYKMENVLDEIIRLDNEMVEGARAGTEKQGPFNGKMTRFIQRLEAKCQDKRLGFMFQISDDELEIDWMNKLCNSLMHGSSNNDKKAGVKIIDFSEVPSDVLPLVIGLVARIVFTVQQWTTNEKRHPICLLCDEAHLYIPERTSQDSASELGLKNFERIAKEGRKYGVSLIVISQRPAEVNRTVLSQCNNFISLRLSNAEDQAVIKRLLPDNLSGLTDVLPILDIGEALIVGDSSLLPTRVIIDEPTIKPQSATIKFWEEWSNDKAEQDISSAVIGLRKQSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC34</accession>
    <name>A0A5C6ZC34_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Helix-turn-helix transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_20065</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000056">
        <property type="protein sequence ID" value="TXD86496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="181"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="214"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="HTH araC/xylS-type" evidence="2">
        <location>
            <begin position="264"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="371" mass="43638" checksum="9004D849F3442AA1" modified="2019-11-13" version="1">MTFSIIELLGVFVVFLFLFFATYLIISKTSKKLSNLIFAVYLIIIALDFTAYFYPKFITLSYSAEMLRMEGLAGLKAPLFYLYILSILYDNFKLKVKHILFFVPLLINLTIIFPNFFNVSIDKQELFFKNYYEQPEAIFVTFFGYIIGFTFLFAGVYQVIRYRKIIKQNYSNPNAFINYTWLKKFLIISFIISAITLAKSIYRFTYNNIETTNNLRITMLLFVIIFISWLFSKALFAPKIFQGIDASLFPLKVNIDEIEDLGIKKIERFMQENEPYLDSSLTLQKLANQLEIPSRELSILINQHMGKHFFDFVNEYRIKKATEKLRNTSSKKITIQEIMYDVGFNSKTPFNTAFKKHTDLTPSQYRKTIDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCF3</accession>
    <name>A0A5C6ZCF3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17930</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000028">
        <property type="protein sequence ID" value="TXD87194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="250" mass="29009" checksum="6D748073E660B1A8" modified="2019-11-13" version="1">MNYIKLLNAAFSTFFFDDRLNPTHISLYMALFQEWNSSRFAGEFYVNRRDLMLASKIGSKSTYHRCVTDLDSYGYLYYFPSNNPYKGSKIQMAIIGTSDEPVLGRYSPILEQVAEQYRPRNVPVTGQQCPISGQAVDSHRPTSGQALVSTINNTKQVNSIKQPKGWQAVFNFFEEKGFDADEAKKFFEHYETRNWQTSDGKEIRDWRALAKNWMDRTELFDEENIPKKNQASQIKDNLRTTKNKDYGQPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCQ9</accession>
    <name>A0A5C6ZCQ9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF1456 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17705</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000027">
        <property type="protein sequence ID" value="TXD87270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009921">
        <property type="entry name" value="DUF1456"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07308">
        <property type="entry name" value="DUF1456"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1456" evidence="1">
        <location>
            <begin position="3"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="80" mass="9431" checksum="2B3EA6D86663E5D8" modified="2019-11-13" version="1">MTNNDIFKKLRVALKLRDDDIIKILELVDFRVSKPELNALFQREDHPNYVECGDQILRNFLNGLVIHLRGPMPNKQKKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCS0</accession>
    <name>A0A5C6ZCS0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19075</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000036">
        <property type="protein sequence ID" value="TXD86859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="175" mass="20643" checksum="0F847201509EABE4" modified="2019-11-13" version="1">MNQTKIYTTRKLEKVTKESIAEDNDKDTEYLGAWTATLFYVSHKKCWLIINKLTKYLLILPDVKKSDLKNIETIFKETLYSQLIYDGIITEFELIEKIIGGIALCETNNDRSVSGSLNNCLPYLEDWNYEFRDFENMPFRDLNNRLNSSPNKMLNWQYPKERMSELLTTYAQNPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCV1</accession>
    <name>A0A5C6ZCV1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GIY-YIG nuclease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_16920</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000024">
        <property type="protein sequence ID" value="TXD87461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035901">
        <property type="entry name" value="GIY-YIG_endonuc_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01541">
        <property type="entry name" value="GIY-YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82771">
        <property type="entry name" value="SSF82771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GIY-YIG" evidence="1">
        <location>
            <begin position="2"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="105" mass="12022" checksum="95DBCF589454112B" modified="2019-11-13" version="1">MKPGFAYLLTNKNNTTLYVGSTSRLVQRIKQHKEKFFPKSFSAQYNLNKLVYFEAFQMIGDAVGREQQLKAGNRAKKVALINGANPEWLDLYEEVKQLFGSDAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCV2</accession>
    <name>A0A5C6ZCV2_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Uncharacterized protein YjiK</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_16465</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the YjiK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009722">
        <property type="entry name" value="SdiA-regulated"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06977">
        <property type="entry name" value="SdiA-regulated"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="285" mass="32280" checksum="E86C3A8AC249B229" modified="2019-11-13" version="1">MKKLKYILIALFSMAVIGVAVGLNWQNDQNPLASEKAYSINKTWEMPKALDEISGIAWLEDDIIASVQDEDGIIFIYDLSSNKIIQEIEFADQGDYEGIAINDQDAYVMRSDGVVFEILNFRSKDKKVSQFKTDFSEDQNMETLFYDRNTKSLITTPKDEGLKSEANKGLYRIALDTKKMDSKAFINIDMNDSALEEFQNKKIEKTFNPSDLAIHPKTGNYYILEGKNPKLMILDPKGNIKNVYVLNEDDFPQPEGLSFESEGRLYISNEASKGASATILQVDFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDC7</accession>
    <name>A0A5C6ZDC7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Helix-turn-helix domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_17790</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000028">
        <property type="protein sequence ID" value="TXD87167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019109">
        <property type="entry name" value="DUF4870"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09685">
        <property type="entry name" value="DUF4870"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="HTH cro/C1-type" evidence="2">
        <location>
            <begin position="5"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="180" mass="20302" checksum="5C59AC20133B226C" modified="2019-11-13" version="1">MGNRLQTYRLEQNMTQTDLAEKAGLSLRTIQRIESGAALKGFTLQSIAAAFGIPPEKLTQYKEDSIDLKRVKIINLSALSFFIIPFGNIILPSILTYKSKDDRVKTFGKDIISVQIIWSVVTSILMIIFPFLQNLVSIKSPLFLIMLVLLICLNVFLIFKNSQSLTRNSTLHIKLKNSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDS2</accession>
    <name>A0A5C6ZDS2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sigma-54-dependent Fis family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_17550</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000027">
        <property type="protein sequence ID" value="TXD87239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025943">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00676">
        <property type="entry name" value="SIGMA54_INTERACT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="3"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="2">
        <location>
            <begin position="141"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD87239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="387" mass="43137" checksum="84C91F8EB007C094" modified="2019-11-13" version="1">MAKILVIEDEASIRRVLVKILSEENDAYKVDEAEDGLAGIEKIKKEDYDLVLCDIKMPKMDGVEVLEAVKKIKPETPMVMISGHGDLDTAVNTMRLGAFDYISKPPDLNRLLNTVRIALDTKVLKVENTMLKKKVSKKYEMIGNSDAIGHIKDMIEKVAATDARVLITGPNGTGKELVAHWLHQKSDRSKGPLVEVNCAAIPSELIESELFGHIKGAFTSAVKDRAGKFETANGGTLFLDEIGDMSLSAQAKVLRALQENRIQRVGHDKDIKVDVRVVAATNKDLNKEIAEGRFREDLYHRLAVILIQVPALNDRRADIPMLIAHFSAKIAEEQGNTKKEFTDEAIKLLQEYDWTGNIRELRNVVERLIILGEAKVSESDVRMFASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDS3</accession>
    <name>A0A5C6ZDS3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_14290</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022868972" evidence="1">
        <location>
            <begin position="20"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="90" mass="10146" checksum="7E251A1BF818A371" modified="2019-11-13" version="1">MKKAILIFALITFPLFAIGQNETVSNVDINSVETMLEKTIDLKETKKEATSDSALKNQVIYINRKKSADIISIKAYRKSLQIKVKTVKLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDU4</accession>
    <name>A0A5C6ZDU4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Zinc metallopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_13910</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007395">
        <property type="entry name" value="Zn_peptidase_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36434">
        <property type="entry name" value="PTHR36434"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04298">
        <property type="entry name" value="Zn_peptidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="150"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="212"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="235" mass="25193" checksum="DE604FFCC06E28B2" modified="2019-11-13" version="1">MGGIGIGYWILIGAIALVSWLVSNKLKKKFEKYSKVHLRNGMSGQEIAEKMLADNGISDVEVISVKGQLTDHYNPKNKTVNLSESVFNQRNAAAAAVAAHECGHAVQHAQAYSALKMRSALVPVVSVTSGMSQWLVIGGLILGAAAGAGFGYWIAVAGLVFMSFATLFSFITLPVEYDASNRALAWLKTGNMLTPEEYKSSEDALKWAARTYLVAAIGALASLLYWAMAVFGGRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEA5</accession>
    <name>A0A5C6ZEA5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">7,8-dihydroneopterin aldolase</fullName>
            <ecNumber evidence="1">4.1.2.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">folB</name>
        <name evidence="3" type="ORF">ESY86_12675</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>7,8-dihydroneopterin = 6-hydroxymethyl-7,8-dihydropterin + glycolaldehyde</text>
            <dbReference type="Rhea" id="RHEA:10540"/>
            <dbReference type="ChEBI" id="CHEBI:17001"/>
            <dbReference type="ChEBI" id="CHEBI:17071"/>
            <dbReference type="ChEBI" id="CHEBI:44841"/>
            <dbReference type="EC" id="4.1.2.25"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 7,8-dihydroneopterin triphosphate: step 3/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DHNA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.25" evidence="1"/>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00154"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004150">
        <property type="term" value="F:dihydroneopterin aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006156">
        <property type="entry name" value="Dihydroneopterin_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006157">
        <property type="entry name" value="FolB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02152">
        <property type="entry name" value="FolB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00905">
        <property type="entry name" value="FolB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00525">
        <property type="entry name" value="folB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00526">
        <property type="entry name" value="folB_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="1 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FolB" evidence="2">
        <location>
            <begin position="4"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU362079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="122" mass="13768" checksum="40BDC06342A033B4" modified="2019-11-13" version="1">MGTIKVENIRVFAHHGCLKEETKIGSDYRVDLKVQANLQTSAKSDKLSETVDYVLLNRIVREEMAQPSYLLETVAKRILNRIFMEDALVTKACVYVSKLNPPIGGDVERVTIKMSESRKNAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEL0</accession>
    <name>A0A5C6ZEL0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_17820</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000028">
        <property type="protein sequence ID" value="TXD87172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="202"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="230" mass="27301" checksum="6AD3F9A224C7E06C" modified="2019-11-13" version="1">MKKIKNILKKIKGLLPKLTKYFFDFLVVFVGVFLAFWLNERKDRQEEETRKQQIYISIYEDFNDFYLSGRKENKEGFIKLFENQKNKMDSLVAIKELPSTCRIFGNYWQIGIINALIESGNLEDVDIGIFKGVTGFQTMHRNMLTEIEAFNEQYEKYITANYDNEIDDFYEPGTNELKQKYKLPLDRLNTLIAQSKMLVEIAKDAKEGLNELYKIEEELKNNQQQQQQQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZET8</accession>
    <name>A0A5C6ZET8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">N5-carboxyaminoimidazole ribonucleotide mutase</fullName>
            <shortName evidence="3 4">N5-CAIR mutase</shortName>
            <ecNumber evidence="3 4">5.4.99.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">5-(carboxyamino)imidazole ribonucleotide mutase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 7" type="primary">purE</name>
        <name evidence="7" type="ORF">ESY86_12470</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 4">Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>5-carboxyamino-1-(5-phospho-D-ribosyl)imidazole + H(+) = 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate</text>
            <dbReference type="Rhea" id="RHEA:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58730"/>
            <dbReference type="ChEBI" id="CHEBI:77657"/>
            <dbReference type="EC" id="5.4.99.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate from 5-amino-1-(5-phospho-D-ribosyl)imidazole (N5-CAIR route): step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the AIR carboxylase family. Class I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.18" evidence="3 4"/>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00943"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034023">
        <property type="term" value="F:5-(carboxyamino)imidazole ribonucleotide mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01929">
        <property type="entry name" value="PurE_classI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033747">
        <property type="entry name" value="PurE_ClassI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000031">
        <property type="entry name" value="PurE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024694">
        <property type="entry name" value="PurE_prokaryotes"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00731">
        <property type="entry name" value="AIRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001338">
        <property type="entry name" value="AIR_carboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01001">
        <property type="entry name" value="AIRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01162">
        <property type="entry name" value="purE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="1 3 4" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AIRC" evidence="6">
        <location>
            <begin position="2"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR001338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001338-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD88547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="162" mass="16974" checksum="81ACFBB43F0AEF9F" modified="2019-11-13" version="1">MSKIAVIMGSKSDLPVMQEAIDILKHFKLEVEVDIVSAHRTPEKLYEFSKNAHKNGISVIIAGAGGAAHLPGMVAAMSPLPVIGVPVKSSNSIDGWDSVLSILQMPGGVPVATVALNGAKNAGILAAQILGSSDPNVQKSIIAYKESMKAKVLEASKELNHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEW5</accession>
    <name>A0A5C6ZEW5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">IS1380 family transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025668">
        <property type="entry name" value="Tnp_DDE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13701">
        <property type="entry name" value="DDE_Tnp_1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tnp_DDE_dom" evidence="1">
        <location>
            <begin position="8"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="425" mass="49388" checksum="C49250E49D0DC8B1" modified="2019-11-13" version="1">MKITLSSDNIKSFGGLNFISAEFDNLQLPALITEHLGERPPQAQFNFSDAIKNMWSIIFAGGDCAEDISANLREEFLQIENLKVCSPDTLLRLQKSLSLDKEVHIGKSGSVNDISRHATLNALNLDMLLQLKTLVPNKLYDLDFDHQFVPCEKYDSRKGYKMEKGYFPGVASIGKEIVYIENRNGNSNVKFKQAETLEDAYSMLKDKRIKIDRSRMDCGSFTKEVIEVVEENSERFYIRAQRCGELSNRVKVMKDWRTVRIGLFDVEVCSIGYTPFGGEKTYRYVVSRQKNNTGQTDAFFGNDFTYRAIATNDRTSTDREIIEYYNQRGATEKIFDEMNNDFGWKNLPFSFLEENTVYMILTAMCRNFYLMILKKIAEKVTFVKPNFRIKKFIFRFVTVPFKWIERGRQKILKLFTQRPYHLLLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF71</accession>
    <name>A0A5C6ZF71_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF3024 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_15385</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021388">
        <property type="entry name" value="Phage_933W_L0084"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11225">
        <property type="entry name" value="DUF3024"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="114" mass="13622" checksum="6FEAF13A3749DE43" modified="2019-11-13" version="1">MTTKTIDINESTIKNYVDSLRPDKPEIRAQLDFGFSYDGKVAILFEIRPAWDDPKEIQQLEFAKIRYYKSKQEWHLFWMRASGKWELYEPFPKSTHLEKIVDTLKEDKHGCFFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF82</accession>
    <name>A0A5C6ZF82_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphatidylserine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_16745</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000024">
        <property type="protein sequence ID" value="TXD87428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016780">
        <property type="term" value="F:phosphotransferase activity, for other substituted phosphate groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="108"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="172"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="212"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="250" mass="28131" checksum="F9FD7C08C5793601" modified="2019-11-13" version="1">MKKFIPNFVTLLNLFSGSIAVLFAVYNNFVAAAIFVFLGIFFDFFDGLLARKLNVQSDLGIQLDSLADMVTSGLVPGIVMFKLLAISLDTEELSTAKEWSSDFEFSSVHMPVLALSGLFITLASAYRLAKFNIDEDQQTYFKGLPTPANALLILSLPLILEFQNSNLITEIIINPWFLIILTLLSCYLLNADIKLFALKFKDYSFKRNVVRYGFIMFTLVMVVLFQFIAIPIVILGYFLTSMLFKSLTAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFK7</accession>
    <name>A0A5C6ZFK7_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosome-binding factor A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1 2" type="primary">rbfA</name>
        <name evidence="2" type="ORF">ESY86_12910</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RbfA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00003">
        <property type="entry name" value="RbfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000238">
        <property type="entry name" value="RbfA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023799">
        <property type="entry name" value="RbfA_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33515">
        <property type="entry name" value="PTHR33515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02033">
        <property type="entry name" value="RBFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89919">
        <property type="entry name" value="SSF89919"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00082">
        <property type="entry name" value="rbfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0690">Ribosome biogenesis</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="131" mass="14701" checksum="753AA551DBAB5A72" modified="2019-11-13" version="1">MEETNRQKKIAGILQQDLADVLQKAATDGGLRGVIISVSKVNVTADLSDAKVFLSIFPNNKAAELLKGIKSNTPLIRHELAQRTRNQLRRMPVLEFFVDDSLEYIEGVEKALKREEDPIKDADLLSKRKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFM5</accession>
    <name>A0A5C6ZFM5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Type III polyketide synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_12790</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012328">
        <property type="entry name" value="Chalcone/stilbene_synt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001099">
        <property type="entry name" value="Chalcone/stilbene_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011141">
        <property type="entry name" value="Polyketide_synthase_type-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11877">
        <property type="entry name" value="PTHR11877"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02797">
        <property type="entry name" value="Chal_sti_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00195">
        <property type="entry name" value="Chal_sti_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000451">
        <property type="entry name" value="PKS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chal_sti_synt_N" evidence="3">
        <location>
            <begin position="35"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="Chal_sti_synt_C" evidence="4">
        <location>
            <begin position="221"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000451-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD88390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="350" mass="39188" checksum="12A42BBB13D41870" modified="2019-11-13" version="1">MKVKITAVAKQLPKYYRETKDIIPFLNVWLDGQEERFQRKVIKLFENAGVDKRYSIMDPEEVFTKTSFQEKNDIYAREVVKLGEQSLKKALDKAQLKPTDIDYIITVSCTGIMIPSMDAYLINNLKMKQDIVRLPVTEMGCAAGVSGIIYAKNFLKANPNKRAAVIAVEAPTATFQLDDYSMVNIVSAAIFGDGAATVILSSYEDEQGPEILDEAMYHFYDAETMMGFKLVNTGLQMILDKAVPETISSHFPQIVHPFLERNGMSIDDVDHLIFHPGGKKIVQTVEDLFGSLGKNIDDTKAVLKLYGNMSSATVLYVLERFMDRNPAKGEVGLMLSFGPGFSAQRVLLKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFS0</accession>
    <name>A0A5C6ZFS0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Heme-copper oxidase subunit III</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_14495</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the cytochrome c oxidase subunit 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019646">
        <property type="term" value="P:aerobic electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024791">
        <property type="entry name" value="Cyt_c/ubiquinol_Oxase_su3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000298">
        <property type="entry name" value="Cyt_c_oxidase-like_su3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035973">
        <property type="entry name" value="Cyt_c_oxidase_su3-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013833">
        <property type="entry name" value="Cyt_c_oxidase_su3_a-hlx"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11403">
        <property type="entry name" value="PTHR11403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00510">
        <property type="entry name" value="COX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81452">
        <property type="entry name" value="SSF81452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50253">
        <property type="entry name" value="COX3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="125"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="COX3" evidence="8">
        <location>
            <begin position="1"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD88091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="193" mass="21959" checksum="66EDFAF60DF5951E" modified="2019-11-13" version="1">MDLTVGTFEEKKDRAKRMMLWFGIISLVMSFAGLTSAVLVSRQREDWLQDYTMPNAFLISCVLIVISSFTFIMAKRALKANNRSLATTMLLLTFGLGIGFILSQLQGFNEFIVQGYNFTGPTSNVTISFIYVIAAVHILHVMAGLLSIMVVIYNHFKQKYTATDMLGVDLSATFWHFVDILWLFLFLFLYYLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG07</accession>
    <name>A0A5C6ZG07_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Adenosylmethionine-8-amino-7-oxononanoate aminotransferase</fullName>
            <ecNumber evidence="4">2.6.1.62</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">7,8-diamino-pelargonic acid aminotransferase</fullName>
            <shortName evidence="4">DAPA AT</shortName>
            <shortName evidence="4">DAPA aminotransferase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">7,8-diaminononanoate synthase</fullName>
            <shortName evidence="4">DANS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Diaminopelargonic acid synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">bioA</name>
        <name evidence="6" type="ORF">ESY86_13640</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only aminotransferase known to utilize SAM as an amino donor.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(8S)-8-amino-7-oxononanoate + S-adenosyl-L-methionine = (7R,8S)-7,8-diammoniononanoate + S-adenosyl-4-methylsulfanyl-2-oxobutanoate</text>
            <dbReference type="Rhea" id="RHEA:16861"/>
            <dbReference type="ChEBI" id="CHEBI:16490"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:149468"/>
            <dbReference type="ChEBI" id="CHEBI:149469"/>
            <dbReference type="EC" id="2.6.1.62"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; biotin biosynthesis; 7,8-diaminononanoate from 8-amino-7-oxononanoate (SAM route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.62" evidence="4"/>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00078">
        <property type="reaction ID" value="UER00160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004015">
        <property type="term" value="F:adenosylmethionine-8-amino-7-oxononanoate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00834">
        <property type="entry name" value="BioA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005815">
        <property type="entry name" value="BioA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00508">
        <property type="entry name" value="bioA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-0093">Biotin biosynthesis</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4 5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="4">
        <location>
            <begin position="110"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="4">
        <location>
            <begin position="300"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="265"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="299"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="388"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Participates in the substrate recognition with KAPA and in a stacking interaction with the adenine ring of SAM" evidence="4">
        <location>
            <position position="15"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="4">
        <location>
            <position position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD88139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="421" mass="47248" checksum="4D85FB42EC01678E" modified="2019-11-13" version="1">MTLKERDKKHLWHPLTQHKLHPHTIAISKAKGCTLTDEDGNNYIDAIASWYTSMYGHCNPYITNRVAEQMQVLDQVVFTGFTHEPAIKLSEALCKILPENQTKLFFSDNGSTAVEIGIKMALQYHSNKSQKRNVLVAFEHGFHGDTLGAMSVSGLSVYNGPFAEFLMDVKRIPTPDDTNHDMVLDHLRKLALEFDIAAFVYEPLVQGAAAMKMHDAEGLDQILKFCNEFGIITVADEVMTGFGKTGKYFASDYMETKPDIICLSKALTGGLMPMAITSCSQKIYDAFYSDEMDKGLFHGHTYSANPLACTAALACIELLTSEDIQTNIKHITERHQDFGERIKSHPKVASIRQKGIIFAMELDVENERYGNLRDTLYNHFMEHGVYLRPLGNTIYIQAAYVISDAELDKVYEVIEGALEIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG20</accession>
    <name>A0A5C6ZG20_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glutamate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_15225</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3 7">Belongs to the Glu/Leu/Phe/Val dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004353">
        <property type="term" value="F:glutamate dehydrogenase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05313">
        <property type="entry name" value="NAD_bind_2_Glu_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006095">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033524">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006096">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006097">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014362">
        <property type="entry name" value="Glu_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033922">
        <property type="entry name" value="NAD_bind_Glu_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00208">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02812">
        <property type="entry name" value="ELFV_dehydrog_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000185">
        <property type="entry name" value="Glu_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00082">
        <property type="entry name" value="GLFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00839">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00074">
        <property type="entry name" value="GLFV_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 3 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ELFV_dehydrog" evidence="8">
        <location>
            <begin position="202"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="240"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="379"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="6">
        <location>
            <position position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD87824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="447" mass="49070" checksum="400C33DB9090D185" modified="2019-11-13" version="1">MKNKIEAFVESVEQKNPHEIEFLQAVHEVAETIIPFIEAHPKYQGKMILERIVEPERSIIFRVPWLDDEGKIQVNRAFRVQFNSAIGPYKGGLRFHPSVNLSILKFLGFEQIFKNALTTLPMGGGKGGADFDPKGKSDNEVMRFCQSFMSELARHIGPDTDVPAGDIGVGAREIGFMFGQYKRLRNEFTGVLTGKGIAYGGSLIRPEATGYGCVYFVKNMLAIKNDTLEGKTICVSGSGNVAQYACEKAIAYGAKILTMSDSSGFIHDAEGIDADRLAFIMYIKNEKRGRISEYLDKYPSATYHEGQRPWGVNCDIALPCATQNELNKEEAETLVNNKVIVVAEGANMPCTPDAIEVFHKSKVLFAPGKASNAGGVSTSGLEMSQNALRLSWPSEKVDEKLHQIMDDIHNACVEYGKDDSGYVNYVKGANIAAFVKVADAMLAQGVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG59</accession>
    <name>A0A5C6ZG59_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11885</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025737">
        <property type="entry name" value="Phenol_MetA_deg_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13557">
        <property type="entry name" value="Phenol_MetA_deg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023062626" evidence="1">
        <location>
            <begin position="20"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="305" mass="34479" checksum="B87FAF3EBB8D1114" modified="2019-11-13" version="1">MFKKILLPSLLLASSLVFAQYTEVINSNRPGVSKSAFSVGTNVAQFEVGPYMIKEEHTPLNYEVSGFGADFSARYGLLFEQLELNIEGIYQNDTFKDNRSAITSERSRANFKSFAVGAKYLVYDPYKNEGQEKPNLYSYHANFGFKWKDLIPAIAVYAGANFDTKDNPYTAPGIEGFSPKVMIATQNNFSGGWVLVLNLIKDRIGTEQSDFQYVVTLTHSFNPQWVVFGETQGIQSDFYADNLFRFGGAYLWSKDFQIDTAVTFNTKDTPSVFGVNLGLSYRLDFHQDKEIDNKNSVEDVDKRRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG62</accession>
    <name>A0A5C6ZG62_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transcription elongation factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_10540</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="1" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="148" mass="16499" checksum="B5ADE43BF51CD428" modified="2019-11-13" version="1">MNKKTQLIEACLEHVNKRISSYKDEIETIKDAIENNDKSSDEADDPGNGKLLNDLEKNSLYLNDAYKMMDTLKLINPKLSHDYVALGSLVTTNTTNFFMAISLGKVDIDGTSYFVISKSSPIGEQLLHKTTGDSISFNHTSYSITDIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGL6</accession>
    <name>A0A5C6ZGL6_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_15035</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. UvrD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013986">
        <property type="entry name" value="DExx_box_DNA_helicase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014017">
        <property type="entry name" value="DNA_helicase_UvrD-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000212">
        <property type="entry name" value="DNA_helicase_UvrD/REP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014016">
        <property type="entry name" value="UvrD-like_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070">
        <property type="entry name" value="PTHR11070"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00580">
        <property type="entry name" value="UvrD-helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13361">
        <property type="entry name" value="UvrD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51198">
        <property type="entry name" value="UVRD_HELICASE_ATP_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51217">
        <property type="entry name" value="UVRD_HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD-like helicase ATP-binding" evidence="7">
        <location>
            <begin position="6"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="UvrD-like helicase C-terminal" evidence="8">
        <location>
            <begin position="292"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="27"/>
            <end position="34"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD87982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="775" mass="88281" checksum="A51DAF7BA4C44505" modified="2019-11-13" version="1">MEKYLSQLNEAQLEPTLQKDGPMIIIAGAGSGKTRVLTYRIAYLMHQGVDPFNILSLTFTNKAAKEMKTRIADIVGTSEAKNLWMGTFHSVFAKILRIEADKLGFPSNFTIYDTQDSDKLIGAIIREMGLEKDVYKTKQVRSKISSYKNSLITVRAYFQNAELIEADTMAKRPRMGDIYKNYVDRCFKAGAMDFDDLLLRTNELLTRFPEVLAKYQNRFRYILVDEYQDTNHSQYLIVRALSDKFQNICVVGDDAQSIYAFRGANINNILNFQKDYDDVKVFRLEQNYRSTKNIVNAANSIIDKNKTKLEKIVWTANDDGGKIKVNRLMTDGDEGRFVASSIFEHKMNDQLKDNDFAILYRTNAQSRAMEDALRKRGIPYRIYGGLSFYQRKEIKDVLSYLRLIINPNDEEALKRIINFPSRAIGQTTVDKLVVAANGYEKSIFEVMKHIDQTEVNVNSGTRNKLKNFVTLIESFQVMNQSANAFELAEHVAKASGIIKEYNKESTPEDIQRLENIEELLNGIKDFVEGQMELVDATGNIAEFLEDVALATDLDNDKGDDDRVALMTIHLAKGLEFPYVYIVGMEEDLFPSAMSMNTRSELEEERRLFYVALTRAEKQAYLTYTLSRYRWGKLIDAEPSRFIEEIDEQYLDVMTPVNDPRQNPMLSADIFGDVEPNHIRFKKPITRKSEAKTPKFVAPKNLKPVKKTGAANANNFKTNLFDGDLAVGSIVEHSRFGKGEVLKLEGKGPDTKAEINFEHGGVKNLLLRFAKLDVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGM2</accession>
    <name>A0A5C6ZGM2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_09485</name>
        <name evidence="2" type="ORF">ESY86_09510</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="507" mass="59103" checksum="7045E78F53608544" modified="2019-11-13" version="1">MKLQTDSTDQLIYENDLLQLTVLGGIKLEGLDRMRSTLKVQLQESSRPPVRHNLDLYNDTQLEKFIRKCAERLEIGTSIISASLSELTEELEKYRLQEIKTKEENLKPKFKKLNLGEIEEAETFLKQTDLLTKTNELIGKSGVIGEEINRLLMYIIFTSRKREQPLHVIGLGSSGTGKTHLQEKVGELIPEEERVSITTLSENAFYYFGKQELKNKVILIEDLDGAENALYPLRELQTKKRIVKTIASKNTKGETQTKYLVVEGPVCVAGCTTKEHIYEDNANRSFLIYLDESTIQDEKIMQYQRQLSAGEINTYEQKEIQEFLQNTQRVLKPITIRNPFANKLNLPQSVFKPRRTNNHYLQFIEAITFYYQYQREQQTDKETGEIYIETTLEDIENANRLLKEVLLRKSDELTGSCRNYLETLKTYLKAKKKKEFTGLEIRTQLRIKESTLRNYHKHLQLLGYIKRNTNKKTRSYTFELVISKDYETLQKDIQTALDKALQNIKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGN2</accession>
    <name>A0A5C6ZGN2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Lipid A biosynthesis acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_11475</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009247">
        <property type="term" value="P:glycolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd07984">
        <property type="entry name" value="LPLAT_LABLAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004960">
        <property type="entry name" value="LipA_acyltrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30606">
        <property type="entry name" value="PTHR30606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03279">
        <property type="entry name" value="Lip_A_acyltrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF026649">
        <property type="entry name" value="MsbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD88849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="300" mass="35748" checksum="2BFE459B67817D30" modified="2019-11-13" version="1">MQFVVYIIVYPLLWLVSMLPFRLLYAFSDFLYLFIYRIFGYRSKTVKENLQLVFPEKSAAEIKTITKQFYHHFCDMMVEAIKSLTISKAEMKKRFRFSNVELLQDLEQRNRSVALMCAHYGSWEWIFILQHYIDNKGYAVYKRLVNSHFDKLIKRIRAKYNSHLITTKETIPILMRAKVKGTPFICGFVSDQSAKPNKALHWGEFMGYKVPMHTGAEMLAKRLDLAVVFFSVKRLKRGYYETSFETITENAKDFENYEITDMFFRLTEAQIKSAPQYYLWTHKRWKHKDKSASDYHEVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGP3</accession>
    <name>A0A5C6ZGP3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hydantoinase/oxoprolinase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_12880</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008040">
        <property type="entry name" value="Hydant_A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002821">
        <property type="entry name" value="Hydantoinase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045079">
        <property type="entry name" value="Oxoprolinase_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11365">
        <property type="entry name" value="PTHR11365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05378">
        <property type="entry name" value="Hydant_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01968">
        <property type="entry name" value="Hydantoinase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydant_A_N" evidence="2">
        <location>
            <begin position="2"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="Hydantoinase_A" evidence="1">
        <location>
            <begin position="202"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="686" mass="76537" checksum="5C1D823C9BF2B047" modified="2019-11-13" version="1">MRVATDIGGTFTDLVFFDFDRETKEVKKVEVSKSSTTPGEFEKGILNAIKKIDLDLNTIDFFAHGTTVVINAITERKGSKTALITTEGFRDVLEIARGTRPDLYNFNFKKEEPFVERYLRQEVKERINYLGEIITPLDDTSVDKHIEAFIEEGVEAIAICFLHGYKNPIHEKQLATYIRAKYPQFEVITSHEVTREWREYERTSTTVLSAYVKPLATKYLNNLTHHLQKLGYKNDLYIMQSNGGITTVEDVKANPITLIESGPASGMLGAVVLGKTIGKENLLVLDIGGTTAKCSLIENGTPKIVTTYNIEKTKTQAGFPILTPVIDIVEIGNGGGSIAWLDDGGKMRVGPKSAAANPGPSSYGKGGSDFTTTDANVVCNRIHKDYFLGGELKPDFDSLEKAAKPLCEELDMTIEEVARGVIRVANSNMVNALKSVSVNKGYDPRDFTLVVIGGGGPMHGAYLAEELQMPEVIVPLNAGVFSAFGMLMSDLRRDYIRTDVMDLNEDKFSALKNVFKEMKNEAIKAYERDGYQKEDIKFEYYLDLRYKGQEHSVKLGLASLSNLKMDEIENNFHQLHKKRYAFSLADTNIEIVNYHLVAEVIVNKPVIGKVESRGNTVEDALITTEKVDFDVYGIHDSNFFDRDKLDPGMTIEGPAIIVEQSTSTVVPPKYQFRIDEYANIIISKIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGV6</accession>
    <name>A0A5C6ZGV6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12505</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="165"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="203"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="230"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="256"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="277" mass="31911" checksum="ECA0AEA145D9624C" modified="2019-11-13" version="1">MKALKAIFDFYINSSIHVALAVFALSWLTLLEFGLPYDGDLLYFIFFASITGYNFVKYFGLVKFHYRSLARWLKVIQVFSFLCFLLLLYFAAFLEVATLLFISIFAGITFLYAIPLLPKNLFLDQKQKLRSISGVKIYIIALVWSGVTVFLPLLNAGYHLNSDELLMALQRFVFVLALMMPFEIRDLSYDSIKLATMPQIIGVVNTKLMGLVLLLIFVLIEFFIKTARVQQFEILFVIALLSAAFIIGSKKNQHRYYSGFFVEAIPIVWLVLWLFMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGZ7</accession>
    <name>A0A5C6ZGZ7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2384 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11615</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024467">
        <property type="entry name" value="Xre/MbcA/ParS-like_toxin-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09722">
        <property type="entry name" value="DUF2384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2384" evidence="1">
        <location>
            <begin position="88"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="139" mass="16381" checksum="41FA65EABD9673F7" modified="2019-11-13" version="1">MDTTKDLIRDIPANISDSQVITYLHSANIGTRQLRQFKTLTHATDKVISEWFNVSEKTVLNYRSSKTKLNINFKEKLLLLFSLYKLGERVFGSKEEFNDWLEKPNFHFNDERPEHFFKTISGIRYIEDRITGIEYGDNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH42</accession>
    <name>A0A5C6ZH42_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cysteine synthase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_11900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PALP" evidence="3">
        <location>
            <begin position="13"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="345" mass="38770" checksum="5C1C8070F0CB7164" modified="2019-11-13" version="1">MKKDRQVFDNVLQLIGKTPLIKLNKMTEGFKGEFYAKVEAFNPGHSSKDRIALHIIEEAERKGILNPGDTIIETTSGNTGFSIAMVSIVKGYKCILAVSSKSSPDKIDMLRSMGAQVYVCPANVKADDSRSYYEVAKRLHKETEGSIYINQYFNDLNLDAHYQSTGPEIWEQTEGKITHLIACSGTGGTISGIAKYLKEQNQEVKVIGVDAYGSVLKKYHETREFDEKEIYPYRIEGLGKNLIPTATNFDLIDKFVKVSDEESAHMARKISKTEGLFVGYTSGAAMQALKQLEEEGEFKAGDRVVVIFPDHGSRYMSKVYSDKWMEDQGFFDNEKISAEKIQYIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH49</accession>
    <name>A0A5C6ZH49_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022820202" evidence="1">
        <location>
            <begin position="19"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="240" mass="26749" checksum="4C9AAB2AD7140D56" modified="2019-11-13" version="1">MKKSLLLLILLSVQILVAQSAATVENPPSKATDLVLFSFGMEQPIPIGTLSNSGELNINLAQDLDFISEEAKSNFMSDTAFILFSNCVGSNDMLSEAENVKAAKGGYISLSTKENPYSGLLFMVTDENMVPWIESYGDVDAILGSYFEVVYMESDFSYQGECTSNASSTEKEIIETQYTYDLNLKAGFNFIEYKIESVEEFEIPSMYEENVFEKIDKPTKISITSSQSTLPNTKWIGKYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH69</accession>
    <name>A0A5C6ZH69_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_08920</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="106" mass="11889" checksum="7DE97E2A36753048" modified="2019-11-13" version="1">MSTYLKNSISFFFLTTFLLLKVANLHEVSHITSDKDTEHCEQCAFIAQAGQTTPLNVATPQESISFVNPFDFAEHSNAYTLYVAPQQKVLHSDYFHNKPPPNPSLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH79</accession>
    <name>A0A5C6ZH79_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4199 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025250">
        <property type="entry name" value="DUF4199"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13858">
        <property type="entry name" value="DUF4199"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="149" mass="16967" checksum="D23D18D411DA8EF7" modified="2019-11-13" version="1">MSVRVALRYGIFMAISLIAYFLIVRLFDLHENPWLRLLNGVVMVAGISLAIKHYKLIDAEGLSYINGIKIGILTGFTATIIFTIFMAIYMFHIDPEFTQTILEDWLRNYDSGAGVLVFIIFLEGMGSSVVLSLALMQFFKKSYQKQQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH86</accession>
    <name>A0A5C6ZH86_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_09885</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="4"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="251" mass="28412" checksum="E080706A0259DE22" modified="2019-11-13" version="1">MKVSIITATYDSELTLPDCMASVLSQSHEDIEYVIIDGDSKDGTLGFIESKAKAHANIVYASEPDKGIYDALNKGIQMATGDVIGFVHSDDYLADPKVIENIVTAFEQHKADGVYGDLHYVSFEDPQKLIRNWKSQVFQNKLLQRGWMPAHPTLFLKREVYLQKGGFNLGYKIAADYDFILRVFRDPSYSFQYVPITITKMRLGGASNKSLKNLIQKTKEDYRASKSNGLSLPFKVILLKNLSKIPQWFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHD6</accession>
    <name>A0A5C6ZHD6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chromosome partitioning protein ParA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11965</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="297" mass="33223" checksum="08E508B83D32441B" modified="2019-11-13" version="1">MENSNANTSNGGSGLKIAVVILLVLFVGTGIYTFNLYKNNKENETALIKEKNQVMTDLNVMAKQYDVAIAENQVANEDLLGARERIQGLIDSLKVSQNSVNSLWGYRTKFNALQKEMDVLMAENSQLKSQNSLLSTSLDSTNVRLAERNMFSDSLLVQNTQLAEVVENAAVLQTVDLKGFGVIERNSGKLIPTERARRSDKIRVCFTIAKNALVGAGDKELYIQVLDPRSNVLGANEQIQFGEKILNYSLVSKFNYENRNLNICEFIAPNDEFEEGRYIVNVFNKKELISSTEFTLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHK6</accession>
    <name>A0A5C6ZHK6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_11705</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016624">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transket_pyr" evidence="3">
        <location>
            <begin position="349"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="666" mass="74200" checksum="CE31B201DAC9008A" modified="2019-11-13" version="1">MLTSSKSVIAYDKKNLDDATLVSLYKNMLKPRMIEEKMLILLRQGKISKWFSGIGQEAISVGVTMALNKEDYILPMHRNLGVFTTREIPLYRLFSQWQGKMNGFTKGRDRSFHFGTQEFNIVGMISHLGPQMGVADGIALASLLKNTNQVTAVFTGEGGSSEGDFHEALNVASVWSLPVIFCIENNGYGLSTPTNEQYNCKDLADRGKGYGMEAFVLDGNNIVEVYTKMLKLAESVRRQPRPILIEFKTFRMRGHEEASGTKYVPQDLMDEWGAKDPLENFRAFLREKNILTESQDVEFKASILKEINDHLQQAYNEAAIIPDATIELNDVYQDFEYQQIEAVDDTEEIRLIDAISQGLKQAMEKHDDLIIMGQDIAEYGGVFKITEGFVEQFGKARVRNTPICESAIIGAAMGLSIAGMKAVVEMQFADFVSSGFNPIVNYLAKSHYRWAQNADVVIRMPCGGGVGAGPFHSQTNEAWFTKTPGLKVVYPAFPYDAKGLLATAIEDPNPVLFFEHKALYRSIRQQVPTAYYNLPLGKAAQLKTGNAVSIITYGAGVHWALETLEKNPDIDADLLDLRTLQPLDTVAIFESVKKTGRAIILQEDSLFGGIASDISAMLMEQCFEYLDAPVKRVASMETPIPFMSQLEDQYLAKGKFEAALKTLLAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHX3</accession>
    <name>A0A5C6ZHX3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4274 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07175</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025369">
        <property type="entry name" value="DUF4274"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14096">
        <property type="entry name" value="DUF4274"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4274" evidence="1">
        <location>
            <begin position="2"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="64" mass="7507" checksum="54F312D6D7B8263F" modified="2019-11-13" version="1">MVLNWIVESPKCDKATASLMVLSADPDLYFDHTAETIQDFEKTVWNLLQKILEKFRENEFKNSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIC4</accession>
    <name>A0A5C6ZIC4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Endonuclease/exonuclease/phosphatase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_06850</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="Endo/exonuclease/phosphatase" evidence="3">
        <location>
            <begin position="113"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="328"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="356" mass="41453" checksum="0439BD83CB06BC5C" modified="2019-11-13" version="1">MNYLEIITLVFNILICIPTLASITKFDHWLVRDFDFPRIQISFLLCVNLIAAGLVYSFQQPWHFIIVCALVICLIYQCWLIFPYTYLAKKQTLKFDGKTEKAPISILVSNVLMTNRDYSRLIDLIKLKDPDVFLTLESDKKWEEALEPFEDDYTHSIKVPLDNLYGMHLYSKLPLEGMQVKYLIKDDIPSIHGYIKLDNGKKVRIHCLHPRPPSPTESKTSTGRDAELMLIGKQIEADPSLTLVFGDLNDVAWSRTTKIFQKVSGLLDPRRGRGFFNTYSTEHFFMRWPLDHVFHSDDFTLIDISREKNIGSDHFPMYIKLNYTPEKTEEQDKLEVNQDEEDWASKKVKDGKEEDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIE9</accession>
    <name>A0A5C6ZIE9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 10 11">Ribulose-phosphate 3-epimerase</fullName>
            <ecNumber evidence="7 10 11">5.1.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">rpe</name>
        <name evidence="15" type="ORF">ESY86_09915</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10 11">
            <text>D-ribulose 5-phosphate = D-xylulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:13677"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="EC" id="5.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10 13">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="10 13">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Carbohydrate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 10 11">Belongs to the ribulose-phosphate 3-epimerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.1" evidence="7 10 11"/>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00345"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004750">
        <property type="term" value="F:D-ribulose-phosphate 3-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019323">
        <property type="term" value="P:pentose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00429">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02227">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026019">
        <property type="entry name" value="Ribul_P_3_epim"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000056">
        <property type="entry name" value="Ribul_P_3_epim-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11749">
        <property type="entry name" value="PTHR11749"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00834">
        <property type="entry name" value="Ribul_P_3_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001461">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01163">
        <property type="entry name" value="rpe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01085">
        <property type="entry name" value="RIBUL_P_3_EPIMER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="13" id="KW-0170">Cobalt</keyword>
    <keyword evidence="9 10 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="13" id="KW-0464">Manganese</keyword>
    <keyword evidence="8 10 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="10 14">
        <location>
            <begin position="143"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="176"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10 14">
        <location>
            <begin position="198"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10 12">
        <location>
            <position position="36"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10 12">
        <location>
            <position position="176"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10 14">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 13 14">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00009541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR001461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TXD89081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="220" mass="24538" checksum="6E3D6427A331BFC4" modified="2019-11-13" version="1">MPEKLIAPSILAADFGNLQRDVEMVNNSDADWFHIDVMDGHFVPNISYGMPVIEAIKKHAKKPLDVHLMIEKPERYIEEFARVGADIISVHYESTVHLHRTLCQIEDAGCKPAVVLNLTTPVSVLEDILPKCYMVLLMSINPGFGGQKFEQMTYNRIKKLRKMIDDQGLDTLIEIDGGVTNLNAKQLVDAGANVFVAGSYIFKSANQPETIKSLRTLVNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIK7</accession>
    <name>A0A5C6ZIK7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha/beta hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_11125</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002018">
        <property type="entry name" value="CarbesteraseB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00135">
        <property type="entry name" value="COesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022889715" evidence="1">
        <location>
            <begin position="20"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="COesterase" evidence="2">
        <location>
            <begin position="33"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="274" mass="31163" checksum="9EBD3644B75A85C2" modified="2019-11-13" version="1">MKINQYLLILLMLPFFNCASRKFKDVPYTKGISKTDSLKLNVFEPRQPSAEKLPVIIFVHGGNWNTGDKDTYGLIGRNFAKRDVVTVIPSYTLSPKANFDTMAKQIAEALQWTEAHIADYGGDPNQIYLMGHSAGGHLIALISTNPKYLETTKAIKGVILDDAAGLDMYSHLQQQPPKSENNYKTTWTEDPEQWKAASPIYFLSEAAPPFFIYVGTKTYQSIKIQNAAFLERLNKFQPKVSPIYLKKKHVPMVTQFFWPWSDRYEEILGFIGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIL9</accession>
    <name>A0A5C6ZIL9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6444 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_04645</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045618">
        <property type="entry name" value="DUF6444"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20042">
        <property type="entry name" value="DUF6444"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF6444" evidence="2">
        <location>
            <begin position="2"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF20042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="95" mass="10492" checksum="9BC44C25A8569206" modified="2019-11-13" version="1">MNPDKKRIAALEPKSICLESLIEKLLNKIEVLTHRKNSRNSPVSSSKDENRALKSERLRLSQGKSVGGQLGHEGSTIEMTVAPDSIVEHTPAFGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIV5</accession>
    <name>A0A5C6ZIV5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">LysR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_05090</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="307" mass="34837" checksum="F2A1ED1BB66BC6A0" modified="2019-11-13" version="1">MNYTLHQLHIFLKIAELKSITKAAETLHLTQPAVSIQLKNFQDQFPIPLTEVVGRQLYVTDFGLEIATAAEKILNEVHAINYKTLAYKGQLSGRLKISTVSTGKYVMPYFLSGFMKQNEGVDLIMDVTNKTRVVESLELNTVDFALVSVLPKKLKVNKITLMQNKLYFIASNNLEIRKGMSRKKIFEELPLIYREQGSATRNAMETFIANNNFSVRKTIELTSNEAVKQAVLSGLGCSIMPLIGIRNELRNKELQILTVKGLPIVTAWNLIWLKSKKLSPPAVAYLEYLNKEKERVIDEKFAWVDTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIY8</accession>
    <name>A0A5C6ZIY8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_10225</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="301" mass="34554" checksum="1AE15C42C7D6E537" modified="2019-11-13" version="1">MNPIYDVVILTDHRYLSDSKTDTYTRNVYYEDRLVYHALEQLGLRTLRLAWDDMFFDWSSTKAVLFRSTWDYFERFAEFSQWVESISKQTLLMNSGAIIRWNIDKHYLLELQKNNVPIAESHFIEKGAKVSLSQLHDILDWNETVLKPCISGAARHTYKLTSETLAAHEAIFQELIANEAMLLQPFQHNIVEKGEISMMVFNGSFSHAVLKKAKAGDFRVQDDFGGSVINYTPSEAEIDFAEACVKACPELPIYARVDVFEDNSGKIALSELELIEPELWFRYHPNAAMVLAKGIKQRIGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIZ2</accession>
    <name>A0A5C6ZIZ2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_05615</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010559">
        <property type="entry name" value="Sig_transdc_His_kin_internal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06580">
        <property type="entry name" value="His_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="74"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="His_kinase" evidence="3">
        <location>
            <begin position="166"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="139"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD90218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="353" mass="40781" checksum="F43B620750DB2C1D" modified="2019-11-13" version="1">MKIKPQITKPLKRTLRHILFWSLILLFFTSIFGVGNTFEMNVFYFSLFLMPVTIGATYVSIYKLLPDYLISKRYFLFGLYSIYALIILVLTAVFSIFFALAYLTNFKFEKMTVLSKSSVFIIISICLVVIVVSAFKLLKLNLKQSKNSAELEAKILEARLKLKEQELKYLKMQIHPHFLFNTLNSIYGLALKKAEQTPDMILKLSNLLDYLLYQTEKPLVAITEEIDHIKDYISLEKMRFNDTLRVTMDVKLKSEHMTTAPMLLLPFIENSFKHGSLKDGVLKIDIDIKVANEVLYFRIKNSISDHTLAQGGIGLENIKKRLDLLYPNKHELSIVTTDDNFEVYLELKTTANV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ44</accession>
    <name>A0A5C6ZJ44_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_06965</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="218" mass="24097" checksum="742A8FF62C4F9E32" modified="2019-11-13" version="1">MAEIKIEKKKPTWPWVVLVLFILALIAFFAFKDEISDEMTDDYNDDPKTAQYGDSAGTSMGNGATHADYDLDSTATAEVSAYDRSIANSPRSASDSTYSNTAFVNLSQAVARKAKTHDLQSSEALERLERYGNQTNDSSVATNSVEKGILKNFKSISEDVTEVLEAIQTKAYPSLKTEISTLKQHASKLDTNNAWSKQPKQLQSFLEKARAILNNMNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ59</accession>
    <name>A0A5C6ZJ59_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">T9SS type A sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_06060</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022872451" evidence="1">
        <location>
            <begin position="20"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="domain" description="Por_Secre_tail" evidence="2">
        <location>
            <begin position="457"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="529" mass="56296" checksum="C769B57CDF38FADC" modified="2019-11-13" version="1">MKTTITLLIFFIGMASVFAQDPAILWQNTIGGSASDEVLSISPTSDGGYILGGESLSNISGDKTEDSNGSWDIWIVKTNETGALEWEKTIGGNNFDGLGSICQTDDGGYLVTADSDSNISGDKTENSNGSSDYWILKLDATGTIVWQHTYGGGNTDYGPKGLQTIDGGYMVVGSSNSGVSGDKTDPSKGEDDIWVLKLDQNGAIVWQKTIGGNSFDIFSSIAFANDGGYIINTASSSNISGNKSENVIGSDDYWVINLSAEGNVRWDKTLGGTELDFGVDAIATLDGGFLVGGYSNSPISGNKSEDPVGDLDYWVVKLDSDGALIWDRTLGRNYDDLLTDIVELEEGSFLITGSSEADGTGNRTEPSMGLVDNWFVNLNALGVITGQKIIGGDLSDFPANVALRPDGGFVVATTSNSNIAGDKMQASQGAYDYWIYKMDSAFLGLIDIAVTKTILCYPNPNQGNFKIDLGKTYAKVTFQITDITGKIISTSKYASVKTVEMEFDAPAGIYLVDVSLNHGGSKSFKIIKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ64</accession>
    <name>A0A5C6ZJ64_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_07080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="89" mass="9921" checksum="6E1223AE53A47362" modified="2019-11-13" version="1">MNKINASIQENEQRIQALDYLLTLFDRNVLDTVSNQRISQMFTAIFGSGLSYLPSTGVLNDIISSGKLNIILNKSLRQNLASFESSLNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJA9</accession>
    <name>A0A5C6ZJA9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Probable cytosol aminopeptidase</fullName>
            <ecNumber evidence="8">3.4.11.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Leucine aminopeptidase</fullName>
            <shortName evidence="8">LAP</shortName>
            <ecNumber evidence="8">3.4.11.10</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Leucyl aminopeptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">pepA</name>
        <name evidence="10" type="ORF">ESY86_10235</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>Release of an N-terminal amino acid, Xaa-|-Yaa-, in which Xaa is preferably Leu, but may be other amino acids including Pro although not Arg or Lys, and Yaa may be Pro. Amino acid amides and methyl esters are also readily hydrolyzed, but rates on arylamides are exceedingly low.</text>
            <dbReference type="EC" id="3.4.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 8">
            <text>Release of an N-terminal amino acid, preferentially leucine, but not glutamic or aspartic acids.</text>
            <dbReference type="EC" id="3.4.11.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="8">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the peptidase M17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.1" evidence="8"/>
    <dbReference type="EC" id="3.4.11.10" evidence="8"/>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00433">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00181">
        <property type="entry name" value="Cytosol_peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011356">
        <property type="entry name" value="Leucine_aapep/pepB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000819">
        <property type="entry name" value="Peptidase_M17_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023042">
        <property type="entry name" value="Peptidase_M17_leu_NH2_pept"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11963">
        <property type="entry name" value="PTHR11963"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00883">
        <property type="entry name" value="Peptidase_M17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00481">
        <property type="entry name" value="LAMNOPPTDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52949">
        <property type="entry name" value="SSF52949"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 10" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CYTOSOL_AP" evidence="9">
        <location>
            <begin position="155"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="247"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="321"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="240"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="317"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD89137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="469" mass="51476" checksum="F21F8D4F19C8B228" modified="2019-11-13" version="1">MTYTQHNKLDDSKDFIVTCKKADLTSIQKFLPIEKPDFDGSFANYQLLYGSKGNRIYILGLGEEKQAAQLENAFRKLAFETQKHWGKHIQVYAEGFSTEAIKKAVIGLEMAQYAIGEFKSEKEPQRKTALTFVSSEDIKTSLAEGKFTGETINSIKHLVDAPPNIKTPEFLAEWAEKSAKTEHYKCTVLHEKELKDQGFDAVLSVGKGSVNKPVVIINEYQGKPDTAVDIAFVGKGITFDSGGLSIKPSTNLHYMKSDMGGAAVVLGVVELVAKLKLNINIVGIVASAENAVDGNSYRPGDVINSYSGKTIEIIDTDAEGRLVLADGLSYAVKKIKPKYLIDLATLTGSVVRTLGYSAAGMFTKNQEMAQQLSDLGTKVHERVWQLPLYEDFESDLHSDIADIRNLSGKPIAGAINAAKFLEFFTESHENWMHLDIAGVSFGDSPYAKMKSASGYGIQLMVEFVKAKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJB5</accession>
    <name>A0A5C6ZJB5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_07700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013105">
        <property type="entry name" value="TPR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07719">
        <property type="entry name" value="TPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022896203" evidence="2">
        <location>
            <begin position="24"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="76"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="314"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="453" mass="52494" checksum="3E4EB8D77A1FD49F" modified="2019-11-13" version="1">MKIRGYMLLLLFGSICLPQSTHAQVDFNKRPTDDLGNVEDQFQEYFFEALKQKGIENYQKSVDALLKCIDLDDTKAVLYYELGKNYMQLKNFGAAEEAFDEAVSMEPENEWFLDELYGVYIQQDDIRRALKTVKQLVQFHPDYKQDLASLYIRMEKYKDALKILDDMDKNFGFNEDRDYMRNQIYNLTGNDEDRIENLEERVKTNPENEANYLRLIYRYSELGESKKAFDAANRLQTLNPESQMVHLALYKFYLDDNQVQDAIASMKIVLTSPIIKPESKAKVLNDFVKFVAVHQEYETDLIEITAMISEEKSVKTLLELGQYHLQAKEKAKALPYFLEALKQEPKNYAIIKDVLLLKVDLDKNEEAVQMSEEAIDLFPAQPILYLVNAVANNKLKNPKKAIESLETGIDYVIENPNMLRDFYLQLSEAYEQTNNVSKSKSFAQKAEALSTGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJG5</accession>
    <name>A0A5C6ZJG5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">T9SS type A sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_08725</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039448">
        <property type="entry name" value="Beta_helix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13229">
        <property type="entry name" value="Beta_helix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022746726" evidence="1">
        <location>
            <begin position="20"/>
            <end position="1011"/>
        </location>
    </feature>
    <feature type="domain" description="Beta_helix" evidence="2">
        <location>
            <begin position="750"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="domain" description="Por_Secre_tail" evidence="3">
        <location>
            <begin position="939"/>
            <end position="1004"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1011" mass="104065" checksum="A8F6D101A46CA3A2" modified="2019-11-13" version="1">MKKLLLFIVSMTLALTAFSQSTYTVNTTDDLPDININDTVCADANGNCTFRAALQNANKTSNKDTIEFNISGSAPITIAINFDILPNITQPIIIDGRTQAQYAINNTPVIEILNEFLQYSDGIKLYGNSTGSELYGLCVVNFARMTSFPFNFGCGIISNTANHIIQSNYIGLRADGTTLGGNTGGGVSLVNLGGHLIGGIEPFQGNVISGNPSFGLNIGGSIINSYQSFNNVIQGNLFGTDATGTLNRGNRFNLQIVDSYNNTIGGNTPAARNIISGAKSTIDATVGTGLAIEGPASYGNKVIGNYIGTDITGTQSISNVRGGVLILFGANNNDIGTDIAGEGNVISGNGQYGVYLQGDVEIDPVDSNSIKGNYIGVDATGNAPLPNSLGIAMIFGVNNNNTVGGTTPNSKNVISGNTNAGIAITNGNNNQIIGNYIGTDASGTTAITNTIGISVKGGNTSIGGQGAASRNIISGNDTGLEIGENATIATVVKGNYIGLNALGTAAIPNTRGIWLLLTSTNSVIGGTNVLDRNIISGNSFGIFGEGSFHSIKNNYIGLNPSGTSAIPNAAGISFVSTATNTTIGGATALDRNIISGNSNFGIFVSGTSHTIQNNYIGLNSAGTAVIKNNNIGMRLFGTLTNTQISENTISGNGTVSSSARNVEFNSANGAHFFSNKVGTLPDGNTAVTNIGNGVVLATSSNNNIGGVSEIEGNIIGNHNLSGVLMAVTSSNNTFSHNNIGLGLDGVSDIGNGAIGILIIGSNTGNTIVNNTIANNQQGLVLDPAAGIPTQVTISENSIYNNSNLGIDLIGTTANDADDADAGVNNLQNTPEISTINFLGGTAVEITYAVPSAVTNSAYPLTIEFFGAINGQGKFFIESDTYAAPGSKTVTINLPAGFDSNDYLTLVATATDANGNTSEFGISTDSTLSVSQFENTGFKVYPNPVSNILFVKSPASESYSLRLSNALGQVVSTKKGELPSMSLDVTNLSKGLYFLNIDSENGNSKTIKFIKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJJ7</accession>
    <name>A0A5C6ZJJ7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CBS domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_11260</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="11"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="89"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="142" mass="15730" checksum="A7D31E1CBDB5FA8E" modified="2019-11-13" version="1">MNKSAIVKDIMTSRVITLPLNSTLEQAETVLKENKIKHIPIVHENKIVGILSHSDILRISVADAIEDENGDAHDIETTVYDMFTIHQVMAKTVATITPDTTVKEVAKILTAKEFNALPVIENDELVGIVTTTDLIKFLLNQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJM2</accession>
    <name>A0A5C6ZJM2_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Dihydrolipoyl dehydrogenase</fullName>
            <ecNumber evidence="3 13">1.8.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">lpdA</name>
        <name evidence="16" type="ORF">ESY86_11420</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>(R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + NAD(+) = (R)-N(6)-lipoyl-L-lysyl-[protein] + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:15045"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="EC" id="1.8.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11 13">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="11 13">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="13">The active site is a redox-active disulfide bond.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.4" evidence="3 13"/>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004148">
        <property type="term" value="F:dihydrolipoyl dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006258">
        <property type="entry name" value="Lipoamide_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012999">
        <property type="entry name" value="Pyr_OxRdtase_I_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01350">
        <property type="entry name" value="lipoamide_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00076">
        <property type="entry name" value="PYRIDINE_REDOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 11 13" id="KW-0274">FAD</keyword>
    <keyword evidence="4 13" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7 11 13" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 13 16" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9 13" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="15">
        <location>
            <begin position="4"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_dim" evidence="14">
        <location>
            <begin position="339"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="437"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="174"/>
            <end position="181"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="12">
        <location>
            <begin position="41"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="TXD88840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="458" mass="48919" checksum="2601BBB976D08D47" modified="2019-11-13" version="1">MSKYDVIVLGSGPGGYVAAIRASQLGLKTAIIEKESLGGVCLNWGCIPTKALLKSAQVFEYLKHAEDYGLKVKEPGYDFGAVVKRSRGIADGMSKGVQFLMKKNKIDVINGFGKLKTGKKIDVDGKEYSADHIIIATGTRSRELPALPQDGKKVIGYRAAMTLEKQPKKMIVVGSGAIGVEFAYFYNSMGTDVTIVEYLPNIVPVEDEDVSKQLERSFKKSGIKIMTSAEVTKVDTSGDGVKATVKTKKGEEVLEADVVLSAVGIKSNIENIGLEDVGIATDRDKILVNDYYQTNIPGYYAIGDITPGQALAHVASAEGILCVEKIAGQHVEALDYGNIPGCTYCSPEIASVGLTEKQAKEKGLDIKVGKFPFSASGKASASGAKDGFVKVIFDAKYGEWLGCHMIGAGVTDMIAEAVLGRKLETTGHEVLKTVHPHPTMSEAVMEAVADAYGEVIHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJV0</accession>
    <name>A0A5C6ZJV0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">OmpA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_10565</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OmpA-like" evidence="3">
        <location>
            <begin position="141"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="23"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="274" mass="30980" checksum="A3093C78B3233696" modified="2019-11-13" version="1">MKRITLIVAFAFLITSCVSKKKYMALEQEKGELKSELTKTRVENEELEAKFSEIQSRVDNYNSKISSLTEDNNSKLVNVDGVVISENQKKAMRETLKNVPPAYMSTAKTLKDSMNLAVKFNLQKSMDNIEEDEDIDINIQETVVMISISDKMLFNSGSYKISDKANDILSKIANVVNSEESLDIMIEGHTDNQTFVKSSAIKDNWDLSVLRATAVVKKLQNDYGVAPEKLIAAGRSFYQPLTENDSKENRSKNRRTRVVILPNIDKFFALMSQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJX8</accession>
    <name>A0A5C6ZJX8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_08685</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022791">
        <property type="entry name" value="L-PG_synthase/AglD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03706">
        <property type="entry name" value="LPG_synthase_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="128"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="164"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="211"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="246"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="276"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD89448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="322" mass="36714" checksum="C24083E9E2E4C2BE" modified="2019-11-13" version="1">MLVRLSHKTKQFFFVLIKLSVVVAAFYIISHKLTSNDALEISSFLKVLQENELFSIENVFLLLLLTVFNWFFEILKWQLLLKPISPISFKIAAAQSLGALTASLLTPNRLGEYAAKVMYFKKPKRKAVVLLNLLGHLLQMSVTVIFGVIGLWLFQSQQDLGIDYIKISLVIFVIVGLIILVLFLLNKIKMRIKGYSVEKLKHFFQKLPKQTFVYVFLCSVVRYLIFSFQFFLLLKLFKVNISYFDAMTVISSVYLLASIIPSLLIFDVLIKGSVAVYLFGLIAVNGLTVLSVVTLMWLLNFMLPSVFGSYYVLNFKLPKSTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK18</accession>
    <name>A0A5C6ZK18_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ankyrin repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_08905</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022777909" evidence="2">
        <location>
            <begin position="22"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="94"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="268"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="335"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="408"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="441"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="500" mass="55591" checksum="6356F27EDFBE7534" modified="2019-11-13" version="1">MKTMKKLFTLSIFLVSFASFAQLENNVLLDRSFWKGNPDLKTVKQKIAEGNDANALNENAFDAVIYALLEKADDAIVKHLLSFEGNPVDKKTHDSRIYLHWAAYAGQTEMVKYLLDKGSSVTELDSHGYTPLAFAANAGQKNEVLYNAFEKHGVSLTDEKNENGANLLLLVAPSLSTEKELTYFTSKGFKLNSTDNDGDGIFNYATKKGTIDFLKLLIKKDVDYKSLNQEGGNAFLFATQGGRGYSNPLAIYEYLKSLGLEPNIVTNDGYTPLHRLAYNNTDPEIFKLFLTAGADVNQKDAEGNTPFLNAASHNELAMVKLLSKNVKDFNDTNIDGQSALMLALQRNSPEVIEFFMEKGGNAFAKDAKGNTLAYYLVASFDSRKSDEFESKLKLLQEKGLQMNTKQAEGNTLNHLAAKNNDLELLKRLSAFNIDVNSKNDEGLTALHLAAMKAENEEMMKYLISKGADTKIKTDFEESVYDLASENELLKKQNTPLNFLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK19</accession>
    <name>A0A5C6ZK19_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Efflux RND transporter permease subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_04080</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042908">
        <property type="term" value="P:xenobiotic transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004764">
        <property type="entry name" value="HAE1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000731">
        <property type="entry name" value="SSD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00915">
        <property type="entry name" value="2A0602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50156">
        <property type="entry name" value="SSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="338"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="364"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="390"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="436"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="468"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="538"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="866"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="892"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="923"/>
            <end position="947"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="968"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="1003"/>
            <end position="1025"/>
        </location>
    </feature>
    <feature type="domain" description="SSD" evidence="5">
        <location>
            <begin position="368"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD90554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1043" mass="113522" checksum="F4DA2E9A2AB988B1" modified="2019-11-13" version="1">MLKTFITRPVLSTVISIIIVILGILGLQSLSVTQYPDIAPPTIQVSATYPGATAETILESVIIPIEEQINGVEGMTYLTSTATNNGTANITVYFDQDIDPDIAAINVQNRVARANPLLPQAVRQTGVLTQKQQTSALMFISFFSTNEAYNDTYLQNYLKINAVPAFQRINGVGNVTVFGAKDYAMRVWLKPDKMSAYSLTPADVTAAINEQSQEAAAGTLGENNGEAFSYVITYDGRFKNQEQYENIILKSLGDGEFLRLKDVAKIELDAQSYASTANTNGNPSVALGIFQTKGSDAQAIIEEVKAELASLEKDFPEGIDYLIPYDTNEFLNASVEKVTTTLIEAFILVFIVVFVFLQDFRSTLIPAIAVPVSIIGTFFFLNLFGYSINLLTLFAMILAIGIVVDDAIVVVEAVHAKIDEGATDVQKATIEAMSEISGAIISITLVMAAVFIPVTFVTGPSGVFYEQFGVTLIVAIMISAVNALTLSPALCALFLKPHSEEEKKKTYLQRFYNAFNKGFGAMTKKYGQSIGFLYRHKWINVVILLAAIAGIWYASETTPTGFVPDEDRGLVFVNVELAPGASVDRTAEVNRDLRAKIRQVEGVESVTLINGRSLISGAGSNYGLGFIKLENWSERETDETSIDAIIGNLFGVASTIPEAKIIFFSPPSIPGFGNSAGIEVNLLDRSGGDFESLDQVNQEFIGKLSQRPEFQYAQSSFSTKYPQYKLDINVPLAKEYGVDVNNIFNTMQGYIGSIYAADFSRFGKQFRVYIQALPSDRADKQDLSNLFVRTGTGEMAPITQFVSLERTFGPQSVTRFNLFNSTSITGALNKGFSTGDGIAAVEEVAATLPSNYSTAYSGLTREELKAGNQTTTILILVIVFVYFLLAAQYESYLLPFSVLFSLPLGVFGAFITTKLAGLENNIYFQIALIMLIGLLAKNAILIVEFAIQRRRQGESIYDAAIDGAKARLRPILMTSLAFIFGLLPLVLATGVGSEGNRAIGTGAVGGLLIGTILGIFIIPILYMLFQWLQEKVSSKSKPVKEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK30</accession>
    <name>A0A5C6ZK30_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Efflux RND transporter periplasmic adaptor subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_05240</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022678300" evidence="3">
        <location>
            <begin position="21"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="241"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD90152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="501" mass="54372" checksum="A56E0B1C57F14BC8" modified="2019-11-13" version="1">MKYLIIAVFAFLAMSCNEKAEDAHAHNEDGSHAGEEIPRLSHTIWTDKTESFVEFPALIVGSPSRFAAHFTVLDKHQPVREGSVTLSLIKGDKGLRNTAEKPSSPGIFSPTIQPKEAGTYQLVFELKTPDYSDKITINDVTVYANTDDAIKALGTAEEDAGISFLKEQAWKIDFQTAVVVSGEIYDVINTSGVWMPSPGSVKSLAAKSNGVVDFKVNNLTEGTAVKQGQLLMSLNSQGLASNNLSTEIANARSNFNQAKSEYERKKELYDSKIIPKSEFEKVESNFSIAKSNYQSLTSGVSGGSKQIRAPFEGFIKSITVSNGDYVEQGVALVTVGTHQSKVLKTQLAPNYGLSMENVQGIWYQTKNGEWKSVTDAEGEILSIGKDVERENPLISVYAKVNVDVDMPEGSLTPVQIAMGNATQNTMIPVNAILEDYGSYSVIVQLSGESFERRPVQIGKRNGENVEILQGLEVGEVVVTTGAYQVKMASMSGSTPAHGHDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK71</accession>
    <name>A0A5C6ZK71_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="415"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="440"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="472"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="503"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="549"/>
            <end position="572"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="585" mass="68478" checksum="4834883560CBA365" modified="2019-11-13" version="1">MKSFIYKVNQYLIERYPTVWNTKLVWMLASAIILHLLFFVMGFFTISNPASLQERGINDIFFENGAVFMSVIITILMLVIWLVYLFKNNAFKNFYPTSRAGLFLAFLYHILIIFVSSSFYLSYNYGMKAQIALSYSDARIADEIALANEAAVFFSEKVSDYTLDKREYPEPFDQLFCETRDKLIDYNQPYTSFLDNNYQFFSIYKKEASKTPRYSEPQFTGYIYKKSLDSMDVYYFKDKLIDVSNLINNSLPSYYNYSSTLYISKNDSLNQEDLDYDYDNYSDFGYDHSPQASIRGKLQNKRSHELLRRNNPSEIKQLLSQFLSMSSAYKIKHNLAVDQWFELVYHPTNFEVKSFIRDQKKPDYYYEDDRALLAEKDVNRFLKERLTDYYFESKRLRNVFENIETIKASNPFMDGIHVFMWLAFFLSALIFMFRITGLKSLLFAIVTVGVLILVIALLAILLAYASSGNDNLIGYFISYFAVLLGATIFAIPLFFARSVKKSVVAICLNISIAGFVPYLLLILALIAMHQKDLCEARSFKNDYYNCPTIFDYLEFNWSFVLFFTGLALMYFYTTIIKRWKSLPES</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKB7</accession>
    <name>A0A5C6ZKB7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_07405</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="156" mass="18803" checksum="A9AD43625FE54BFD" modified="2019-11-13" version="1">MAYKKLKPHKIDEATREIELRQLWKVEYCDNNKPVFTHDGIEVSFYEDMFDHCFFESAEWKEKDKSILSLNRLEKMLWIKDTLSDISALMKQGWDRNKKRYVNNRRVNFVKDGYIVVISINKSLTKARFITAFEFQNDEKKQEVLNSPDWIREKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKC4</accession>
    <name>A0A5C6ZKC4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Large-conductance mechanosensitive channel</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10 11" type="primary">mscL</name>
        <name evidence="11" type="ORF">ESY86_03515</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homopentamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the MscL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00115">
        <property type="entry name" value="MscL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019823">
        <property type="entry name" value="Mechanosensitive_channel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001185">
        <property type="entry name" value="MS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037673">
        <property type="entry name" value="MSC/AndL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036019">
        <property type="entry name" value="MscL_channel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30266">
        <property type="entry name" value="PTHR30266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01741">
        <property type="entry name" value="MscL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01264">
        <property type="entry name" value="MECHCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81330">
        <property type="entry name" value="SSF81330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00220">
        <property type="entry name" value="mscL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01327">
        <property type="entry name" value="MSCL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 10" id="KW-0407">Ion channel</keyword>
    <keyword evidence="7 10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD90446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="146" mass="16445" checksum="BD139E07361C52BE" modified="2019-11-13" version="1">MKFFKEFKEFAVKGNMMDMAIGIIIGASFNSVIDVLVKKIFMPPLSLMTDGLNFQDRKYVLRDAITDAKGTITTQEVAIEYGFLFETTLDFLIVGLTVFIVVKAMNRLKDKAEDPKNAVVKTPKDIALLSELTNLMKEQNSLLKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKD0</accession>
    <name>A0A5C6ZKD0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_04630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022947649" evidence="1">
        <location>
            <begin position="20"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="218" mass="24265" checksum="AC2DF81A12CD3370" modified="2019-11-13" version="1">MKKLILALLALNLCYASFGQDSFEEGKVISKQTMTSDNEQAKAQLAMIGDVETTSYFKGNKTRAEATSPMTGKVISIIDGDSNKMLMLMDSPSMGKVYMLQDISLSEADKKNMEIKKGDETKSILGYECQQYFVTMTKDGQTMKMEMFTTDAISAMSQQTATFNDKISGFPMYMSMDVNQMGMNMTITNEVTSIDEEKVDSGIFDLTPPEGYKDMQPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKM2</accession>
    <name>A0A5C6ZKM2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_09015</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="198" mass="23448" checksum="5077737FCACDB391" modified="2019-11-13" version="1">MRIFADDLFAAEWFPRIARIFADVLFASEWFPQIARIFADVLFASEWFPRIARIFADGLFASEWFPRIARIFADGLFASEWFPQIARIFADDLFAAEWFPQIARIFADDLFASEWFPRIRRIFADGLFASEWFPQIARIFADGLFASEWFPQIARIFANVLFASEWFPQIAQIFADGLFASEWFPRIARIFRRCFVRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKQ6</accession>
    <name>A0A5C6ZKQ6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF3667 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_04250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022134">
        <property type="entry name" value="DUF3667"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12412">
        <property type="entry name" value="DUF3667"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="197"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="230"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="266" mass="30342" checksum="A95E51CEC4580996" modified="2019-11-13" version="1">MDCKNCYLPLAEASQFCHSCGGKVIKKRLSFKNLCAHVGETFFNYDNKFLSTFIDLFKKPEVVIDSYVQGTRNRYVNPIGFFGIILTLNGLNIFIINKFYKKYLDATDLVGNIDAANNEATKKIMALSTDISLEYASLFFSLLIPVAALVSLIVFYNKSYNYTEHVIVYLYSMSVYSLLSVVFGLSVLAIAPDYYFTFANVMYVFIVVYHCYILTRLFKLSIKQLTIKVLLFLIAFFIIYIGTSILVVFILFFTGTVNPQDFLPPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKR9</accession>
    <name>A0A5C6ZKR9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_04355</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="316" mass="36814" checksum="B6AAC574284FF965" modified="2019-11-13" version="1">MKDILINEELLEKIRKFKFIETLNSVETINIVPDVLTHHHLLMYRSIDEAIKQSYIAQNKSLLYKEEWQKLSKNSNYSIYGQAISPFPFVIEGAYHSRISLWTKINSLLHPFEKHTLEGNHNLNSLLDLKPYFKKYAEGFNEGFNDFEKDLITPLLLNLGSPDRESYANEVFKFITTDRSSSPTVTSGKGFLFTINSDIQFEIGNGYQDGVFEGYHYRAWSIIFSKNELFTPIFKKYLNGEIIANTKKPELKKEDLSKMQNHLISRVSLEYVYEFFSVLGKTPNSKGKFYLNEQKLLIFFKSTFEDNEPIPQSFLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKV9</accession>
    <name>A0A5C6ZKV9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">5-oxoprolinase subunit PxpB</fullName>
            <ecNumber evidence="5">3.5.2.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">pxpB</name>
        <name evidence="5" type="ORF">ESY86_06275</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.9" evidence="5"/>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017168">
        <property type="term" value="F:5-oxoprolinase (ATP-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003833">
        <property type="entry name" value="CT_C_D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010016">
        <property type="entry name" value="KipI_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34698">
        <property type="entry name" value="PTHR34698"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02682">
        <property type="entry name" value="CT_C_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00796">
        <property type="entry name" value="AHS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="SSF50891"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00370">
        <property type="entry name" value="TIGR00370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AHS1" evidence="4">
        <location>
            <begin position="8"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD89808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="246" mass="27978" checksum="DCE248D436ED3657" modified="2019-11-13" version="1">MEKTDFKLIYKRFTERSILVQWPPKINRIILEDVLNFKNELLKNNAKQILQVANAYNSILITYHVTIDNLNTEVSALKQIYEACVSTEKGDTKLWNIPVCYHEHFGLDLAEISELKKLSIADIIKRHSEAIYTVYFIGFLPGFLYLGGLEEQLHVPRKSKPRQRIEKGAVAIGGSQTGIYPNASPAGWNVIGNCPLELFDVNKEPPCFARAGDQVRFYPTDLDEHAKISEAIKNGSYNLEFENSDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKW7</accession>
    <name>A0A5C6ZKW7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03635</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="367" mass="41661" checksum="FCE0C1FFAB86F4F1" modified="2019-11-13" version="1">MKIAFVVLLSIHGLIHLMGFINAFGLAEIPQLSQNFSKPQGLLWLAVALMFVIVAVLFLLKSNLWFWIAFGAVVLSQVLIIMNWQDAKFGSIANVIVLVIAIIALAGRHFEGQYNQDVAQSFENASISKDVVSEEIVSEKDIENLPDPVQKYLRYVGVLGKPKIETAKAIFKGKMREKGKDWFAFTSAQYNFFENPTRLFFMKANFKGLPTQGYHRYKDEEASMLIKLLSMFPVVAIKEPEMFKTETVTFFNDMCLFAPAALIDDKIEWQIIDDTSVKATYTNKKATVSAILYFNEKHQLINFVSADRMDVNSNQKVPFSTPVTKYGTINGYNLPVAADAVWRFPEADFVYGKFYLLDVQYNLKNLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLI3</accession>
    <name>A0A5C6ZLI3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">1-aminocyclopropane-1-carboxylate deaminase/D-cysteine desulfhydrase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_01820</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ACC deaminase/D-cysteine desulfhydrase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027278">
        <property type="entry name" value="ACCD_DCysDesulf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43780">
        <property type="entry name" value="PTHR43780"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006278">
        <property type="entry name" value="ACCD_DCysDesulf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PALP" evidence="6">
        <location>
            <begin position="16"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="5">
        <location>
            <position position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR006278-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR006278-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD90725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="296" mass="33111" checksum="16DC569A646679A8" modified="2019-11-13" version="1">MLEFKDQKNIRISEQLSIKPEYKIHPYISGNKYRKLKYNLLKAQETKQHSLLTFGGAFSNHIAAVAAAGKKFGFKTIGIIRGEELVTEVASNPTLKFAADCGMLLKFVSRSDFRRKNEDSFLEALKSQYGQFYLIPEGGTNALAIKGCEEILTEADAQFDFICCSVGTGGTISGLINSALPHQKVLGFPALKGGFLTEEITKFAHSKHWELMDGHHFGGYGKVSDELIQFINDFKFKYNVPLDPIYTGKMLFGIYDMIQQGFFSKTSRILVIHTGGLQGIEGMNMRLKQQNRSLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLN7</accession>
    <name>A0A5C6ZLN7_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">3-isopropylmalate dehydratase small subunit</fullName>
            <ecNumber evidence="10">4.2.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Alpha-IPM isomerase</fullName>
            <shortName evidence="10">IPMI</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Isopropylmalate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10 12" type="primary">leuD</name>
        <name evidence="12" type="ORF">ESY86_02210</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 10">Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>(2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate</text>
            <dbReference type="Rhea" id="RHEA:32287"/>
            <dbReference type="ChEBI" id="CHEBI:1178"/>
            <dbReference type="ChEBI" id="CHEBI:35121"/>
            <dbReference type="EC" id="4.2.1.33"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 2/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 10">Heterodimer of LeuC and LeuD.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the LeuD family. LeuD type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.33" evidence="10"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00071"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009316">
        <property type="term" value="C:3-isopropylmalate dehydratase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003861">
        <property type="term" value="F:3-isopropylmalate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01577">
        <property type="entry name" value="IPMI_Swivel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01031">
        <property type="entry name" value="LeuD_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004431">
        <property type="entry name" value="3-IsopropMal_deHydase_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033940">
        <property type="entry name" value="IPMI_Swivel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00171">
        <property type="entry name" value="leuD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="6 10" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="8 10 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aconitase_C" evidence="11">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TXD90795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="195" mass="21560" checksum="9323D869CFE0812F" modified="2019-11-13" version="1">MKKFTTLTATAIPLDIENVDTDQIIPARFLKATDRTGFGENAFRDWRFDTDGSINDTFVLNNDNYSGSILVAGNNFGCGSSREHAAWALNDYGFKVIVSSFFADIFKGNALNNGLLPVQVSEDFLKILMGTVLNDAKTKIKVNLIDQTISIEDTAHSEAFEIDAYKKTCMINGYDDIDYLLSKKEAIAAFEGSLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLP1</accession>
    <name>A0A5C6ZLP1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05305</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041657">
        <property type="entry name" value="HTH_17"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12728">
        <property type="entry name" value="HTH_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_17" evidence="1">
        <location>
            <begin position="39"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="94" mass="10702" checksum="3D43E095C387E083" modified="2019-11-13" version="1">MPTSIITTDDLRDFKMELLDDIKKLLTNQSKGKVKKYVKSSEVMDLLQVSPGTLQNLRINGTLPYTKVGGIIYYDTEEIQKVMDANRVQHNLNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLQ1</accession>
    <name>A0A5C6ZLQ1_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Type I site-specific deoxyribonuclease</fullName>
            <ecNumber evidence="3">3.1.21.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">ESY86_07400</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endonucleolytic cleavage of DNA to give random double-stranded fragments with terminal 5'-phosphates, ATP is simultaneously hydrolyzed.</text>
            <dbReference type="EC" id="3.1.21.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HsdR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.21.3" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009035">
        <property type="term" value="F:type I site-specific deoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007409">
        <property type="entry name" value="Restrct_endonuc_type1_HsdR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040980">
        <property type="entry name" value="SWI2_SNF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021810">
        <property type="entry name" value="T1RH-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11867">
        <property type="entry name" value="DUF3387"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04313">
        <property type="entry name" value="HSDR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18766">
        <property type="entry name" value="SWI2_SNF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0680">Restriction system</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="11">
        <location>
            <begin position="274"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TXD89604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1059" mass="122160" checksum="18A5FB00556722AE" modified="2019-11-13" version="1">MNISPEYIHSELPAIKLFQQLGYQYFDASIHDERTDITEVLLKDRLLASIKKINPWINDNNLNKAYTELTSVNGASLMEINQKIWELIRGGTFTVKQVINGVEEFKAVHYIDYLKPDNNDFLVVNQIRFHGRFQNSIPDLVVYINGLPIGIIECKSPTAQNAWDKVFSDLEYYQKNSEKLFHFNQICAGIWDVGGKYGAIHSPQQFYSVFKTSKEDTDIISQSKKEQDKLIIALFKKERLLDIIRHFVLFELEEGRTIKKLPRYQQLRATNKTIARLQAGEGGVVWHTQGSGKSLTMVYVARKLQAPEFGFDNPTVMIMTDRKDLDRQITTTFQNVGFKNVNQASSVIHLDKLLRNDYGGIITTTLQKFQETDKESTDTTDQTELEERGNLRIEKLLNDKTLIKITKEFQKGKWVEIEREEIDLEELSTKENLYVLVDEAHRSHYGFLASFMRTVLPNAKFVAFTGTPISKEDKSTLGEFYGGDYIDVYTITEAVADGATVELLYDEGTALLSVKKEELDEEFEAKFGHYSEDKKDKLKREALRKYQLSKERIEVIGKHMIDHFRDKIFPDGHKAMIVCSGRKAAIKYQQTLHQLREEGYHDFDSKVVVSIGSPKSDAIAKDYYETLEWNRNNPTNPKPIYVVPPEAIKDATDNFKLPFGNEAETEKSGKKKFDNTAFIIVSDMLLTGWDAPIASCLYLDKPLKEHNLLQAIARVNRSRKGKSAGFILDYNGITTYLIQALEIFSGDIRPDDILKNINEEFPKLEMNHTKLVDFFNPMKIDRKYHRNDYIDAAVRYIEPMNLRDDFKVFLKDFNKSINIVLPNTKALKYQDDFKLFNEIKLRARNAFPDDDELKISKDESKMLQGMIDEHLKAEGVENLLREPISIIDKDKFKEEIMNASPATKELKMRNNLKHTIKVGIDKNPDFYKPLAQRLDELLKQKKDERITQLDLLKAYADIQDKIIAQQREGKDKGFNTERERAVYDSMKVMFGYDAEDATKTIFDLIKGELNIVGWQAKGQVQKDIENKIRRYLTTAKIEREDAKAKAKEMVAVLIKNEDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLV1</accession>
    <name>A0A5C6ZLV1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_02075</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="201" mass="22561" checksum="BFE734E6C2E320A2" modified="2019-11-13" version="1">MNKLLASISYIFHPLLMPLLGVVFYFSKTPRFVPEPVIKAKLFSIVILTIVLPILLYVLLKTLKKVKSLHLQTTEERRLPLLINCAIILLIVNRVFPLGEIPELYFFFLGILISTITCLALALIQFKASIHMIGAAGFFMFAVAVGIHFKININGSLALMFIILGAIASSRLHLKAHSPLELIMGFFVGLLPQLIILNYWM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLY7</accession>
    <name>A0A5C6ZLY7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TetR/AcrR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_00425</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="21"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD91096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="227" mass="26174" checksum="B083CB47F45C331A" modified="2019-11-13" version="1">MSVEIKISLNEGVYLKDPQDSRLGRNIIKHGILLIEELGFEAFNFKKLAKEIGSTEASVYRYFENKHALLIYLVSWYWQWVSYLIKINTLNLDDPKKKLKIIINSFVSASVENPSTEYIDENKLHSVVIAEGTKAYRTKGVDDENGKGFFKNYKQLIAMVAAVILEINPTFEYPHAMASNLFEMSNDHIYFAKHLPRLTDIKLSENTYPEVEEMLNYFASKLLGYKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM55</accession>
    <name>A0A5C6ZM55_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase</fullName>
            <ecNumber evidence="2">2.7.6.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">folK</name>
        <name evidence="10" type="ORF">ESY86_02685</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 7,8-dihydroneopterin triphosphate: step 4/4.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.3" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003848">
        <property type="term" value="F:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01673">
        <property type="entry name" value="dNK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00483">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031314">
        <property type="entry name" value="DNK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000550">
        <property type="entry name" value="Hppk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035907">
        <property type="entry name" value="Hppk_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01712">
        <property type="entry name" value="dNK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01288">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55083">
        <property type="entry name" value="SSF55083"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01498">
        <property type="entry name" value="folK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="5 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HPPK" evidence="8">
        <location>
            <begin position="8"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="dNK" evidence="9">
        <location>
            <begin position="183"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD90882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="374" mass="43742" checksum="4B41B4EC3B30E255" modified="2019-11-13" version="1">MNSNHHVYIALGSNKGDRLKLLQDAVNLIFSEIGNVNSIARVYETPAFGFEGGDFLNTCILVETTFSAEIVLQKLQAIESRMGRERTSSETYQSRCIDLDILFFDAEIIATEDLKVPHPQLQHRKFVLQPLQDIAAKLKHPQLQQTVGDLLKTCLDESSIEPINIWLKNPAKQYDFSKYNYVAIEGNIGAGKTSLAHQLSKDFNAKLILERFADNAFLPKFYEEPLRYAFTLEMSFLADRYQQISDDLSQLDLFRDFIVSDYDIYKSLIFSKITLPEDEFILYRRLFYLMYKDIAKPDLYIYLYQNTQRLQENIKKRGRDYEQNIEDDYLDKINSGYLDFLKNQTELKVKIIDISERDFVNNRKDYLWVLEQIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM86</accession>
    <name>A0A5C6ZM86_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Exopolyphosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003695">
        <property type="entry name" value="Ppx_GppA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02541">
        <property type="entry name" value="Ppx-GppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ppx-GppA" evidence="1">
        <location>
            <begin position="42"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="304" mass="33838" checksum="18816FF73A3CD4E6" modified="2019-11-13" version="1">MLTIKKYAAIDIGSNAVRLLIANIIEQKGKATAFKKSSLVRVPIRLGSDVFVNGAISEENKKRMVDTMTAFKLLMKSHKVCTYKACATSAMREADNGAEISKLIEKKADIFIDIIDGEEEAAIIAATDLQSYIKEDKTYLYVDVGGGSSEFSVIHLGKTVASRSVKIGTVRLLNDIVKKETWLELETWIKLVTKDYHKVDLIGSGGNINKIFKISGKALGKPLTYFYLTSYYNKLQTYSYEERITELELNQDRADVIIPATRIYLSAMKWSGAKDIYVPKIGLSDGIIKSVYYKTVSSVDLALD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM97</accession>
    <name>A0A5C6ZM97_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="7"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="335" mass="38548" checksum="19B08484021381D3" modified="2019-11-13" version="1">MDHPLISILIPYKNTADFLSACLKSIVAQTYAHWELLIVNDHSQDDSAAIVHAFAEDDQRIKCLENAGSGIIDALRKAYDASQGQYVTRMDSDDIMHPQKLELMLKDLQKYGQKHLALGLVSYFSESGVGDGFKSYESWLNALTRNGDNFKEIYKECVIPSPCWMLHRADFEACGAFRSNTYPEDYDLAFRFYKKGLTCIPSDQLLHHWRDHQNRASRTDAHYAENSFLDLKVRYFLELNHEASRPLCIWGAGKKGKSVAKLLQAKKVSFHWLCDNPKKIGKHIYEVLLQQYQDVEHLAQPQIIVAVANPEAQQEIKSYLKKHDKEAMEDYFFFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZME4</accession>
    <name>A0A5C6ZME4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Putative K(+)-stimulated pyrophosphate-energized sodium pump</fullName>
            <ecNumber evidence="9">7.2.3.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Membrane-bound sodium-translocating pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Pyrophosphate-energized inorganic pyrophosphatase</fullName>
            <shortName evidence="9">Na(+)-PPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">hppA</name>
        <name evidence="10" type="ORF">ESY86_02495</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na(+) movement across the membrane.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>diphosphate + H2O + Na(+)(in) = H(+) + Na(+)(out) + 2 phosphate</text>
            <dbReference type="Rhea" id="RHEA:57884"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="9">Requires K(+) for maximal activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-stimulated subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.3.-" evidence="9"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030955">
        <property type="term" value="F:potassium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009678">
        <property type="term" value="F:pyrophosphate hydrolysis-driven proton transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01129">
        <property type="entry name" value="PPase_energized_pump"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004131">
        <property type="entry name" value="PPase-energised_H-pump"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31998">
        <property type="entry name" value="PTHR31998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03030">
        <property type="entry name" value="H_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001265">
        <property type="entry name" value="H+-PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01104">
        <property type="entry name" value="V_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0630">Potassium</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0915">Sodium</keyword>
    <keyword evidence="9" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="5 9" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="58"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="82"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="127"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="178"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="255"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="285"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="333"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="371"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="416"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="446"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="512"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="543"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="612"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="638"/>
            <end position="660"/>
        </location>
    </feature>
    <feature type="site" description="Determinant of potassium dependence" evidence="9">
        <location>
            <position position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD90848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="811" mass="84914" checksum="4BCD2AF6799927B1" modified="2019-11-13" version="1">MESLMIYMPIAMAILGLIFMLVKQSWVMKQNPGDGKMKEISDHIYEGALAFLKAEYKLLAIFVVIVSVLLAIVSFVVPTTHILIVVAFIFGAFFSAFAGNIGMKIATKTNVRTTQAARTSLPNALKVSFGGGTVMGLGVAGLAVLGLTTFFIGFFYFFMDSTWAAQVINGRNYSPTELMTVVLETLAGFSLGAESIALFARVGGGIYTKAADVGADLVGKVEAGIPEDDPRNPATIADNVGDNVGDVAGMGADLFGSYVATVLAAMVLGNYVIKDMGGDISEFGFGGIGPILLPMAIAGVGIIISIIGTLLVKIKSNDAKEDQVMSALNIGNWTSIVLVAVSCFGLCHYMLPETMQMRFFGLVEPVEISSMRVFYATLVGLVVGATISSVTEYYTGLGKKPVLKIVQQSSTGAGTNIIAGLATGMMSTFPSVLLFAGAIWGSYAFAGFYGVALAASAMMATTAMQLAIDAFGPISDNAGGIAEMSEQEPIVRERTDILDTVGNTTAATGKGFAIASAALTSLALFAAYVTFTGIDGINIFKAPVLAMLFVGGMVPVVFSALAMNAVGKAAMEMVQEVRRQFKEIPGIMEGTGKPEYDKCVAISTEASLREMILPGLLTICFPLAIAFLPMLFGMDPLAIAEMLGGYMAGVTVSGVLWAIFQNNAGGAWDNAKKSFEAGVIINGEMTYKGSEAHKAAVTGDTVGDPFKDTSGPSMNILIKLTCLIGLVIAPILGGHSLEEGMAVSQTNAEAVVVRTISTETDADGIITNSAEAKVTTTTQNNGQTVIVEKLFKGTLEEVTEASSAYAKAQKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZME7</accession>
    <name>A0A5C6ZME7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type II toxin-antitoxin system HicA family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_03700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012933">
        <property type="entry name" value="HicA_mRNA_interferase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07927">
        <property type="entry name" value="HicA_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="85" mass="9877" checksum="846B4AF586661C57" modified="2019-11-13" version="1">MSKIEKLIAKFQSNPKDLTWEELIKILVHFGFVELSKNGKTGGSRVKFANENKDIINLHKPYPSNIIKPYLIKQIIEKLKAWQII</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMG0</accession>
    <name>A0A5C6ZMG0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">WbqC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_00640</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014985">
        <property type="entry name" value="WbqC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08889">
        <property type="entry name" value="WbqC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="207" mass="24532" checksum="CC0E6995B8125218" modified="2019-11-13" version="1">MTVLLHPAYFPNVAHFVAMLQADEILFEACDNYQKQTYRNRTTIFDANGSLDLNVPVVYSQKNRQQYKDVKIFNVEPWQQQHLKSLESAYRTSPFFEYYIDDLLPVFTEEFTNIMTLNMSCLELIFECLQLPFNYKLTNNFEIEPEHVMDARRLINCRKEIKQNFNAYAQVFDKNHNFLSNLSILDLLFNEGPATELYLKKQILQTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMG3</accession>
    <name>A0A5C6ZMG3_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">TonB_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_02550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037682">
        <property type="entry name" value="TonB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03544">
        <property type="entry name" value="TonB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TonB_C" evidence="1">
        <location>
            <begin position="116"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="180" mass="20721" checksum="3125B2F1CE4B3120" modified="2019-11-13" version="1">MFPLEREQSKIRWPDEIFNAYDYKPPYKNIIMKNLLVLFILFSGVKFFAQENTLHSNPKEDIQITGETVPVYKGCENNTSNKDLKQCMSNEISRHFQRNFRTSRPPISKLKKGTYTIKVIFKIDKEGKITSERAKAKTSDLEKEALRVVALIPQMVPGKRNGKPTVVPYFVPINIQIGGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMH2</accession>
    <name>A0A5C6ZMH2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MgtC/SapB family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_05135</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MgtC/SapB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025105">
        <property type="entry name" value="DUF4010"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003416">
        <property type="entry name" value="MgtC/SapB/SrpB/YhiD_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13194">
        <property type="entry name" value="DUF4010"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02308">
        <property type="entry name" value="MgtC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="42"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="150"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="180"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="242"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="267"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="311"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="371"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="402"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4010" evidence="8">
        <location>
            <begin position="188"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD90133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="423" mass="45832" checksum="1E163732D7A51848" modified="2019-11-13" version="1">MQTFQDLNELVGSYMLGVLISTGVGLILGLEREFDKLKDKGFAGIRSFPIVTIIGFSLGSLTQQFSNWLVIISLGSFILFLALYHFSQKQEEYGQGLTTNLALIATFILGVMVSAEFLKEAVATAVILVTLLSLKTKFVSIISNITSVELFAFIKFSIIALLILPFLPNKNYGPDNLLNPFEIGSIIVIVSLINFIGYFLVKFVGSKKGIILTAILGGLISSTAVAWNYASKSKASPELSKKYSAGIIVASAIMFPRLALLTYIFNAAILIHLALPFALLTLVCIVATLLLMRKDDNKPDTNIKLGNPLDMLNAIGFGAIYLLILFAVFYSNQFFGERGLYYSAFIAGLADTDAITISMAKFSLDSEKTQLATSVIIAATLSNMLVKLGITALKGSKTAGKRVSYAFGSVILVGLAYIFFNTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMV5</accession>
    <name>A0A5C6ZMV5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Mechanosensitive ion channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_02960</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011066">
        <property type="entry name" value="MscS_channel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82689">
        <property type="entry name" value="SSF82689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022986619" evidence="8">
        <location>
            <begin position="27"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="234"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="277"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="306"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="360"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="387"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD90968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="582" mass="65913" checksum="1E7B3D97167749D0" modified="2019-11-13" version="1">MKTMVNAFLFILLSNMVGIGVYTAKAQDSTSTNVPSKDSTIVKANIKTSSFQGSEENYYVIQHRNQFFDRSEMSVNRETPQASLENFILSARNADYLKAAHSFNLNLISDDVSNEQIEQLAQKLYIIINKNVSIDWDKLSERPDGQVDKIFAKNKAVAGEPRKSIAFGKLNLKERDVTLRLQRVKYKTEPPYWVISANTVEHIDALYAAYGPTKMVQLVPDGWGLKGEFLKIPIWKIVGLFISMGIAYGLGWITMLILKRIFGRSKWEWISSFSSRLAIPAAYFVGMLALYLLLNNLIVFSGDFANWFYTMLLIATVVCGTWFIMRILNAFIFYMAENRTDDIYAEENLESRQVLTQLSVARRVVSFIIFLTGTGIILSQFESFKNLGTTLFASAGVATIIIGIAAQGTLGNIIAGIQIAITKPAQIGDLVLFDGQWGHVEDIGFVFMIVKTWDERRIVTPLKSVISNSFENWSMRGSKQIRSIDIYTDYRINIQKVREKYEELLKESPTWDKQISPSVQVVESTEKAIKIRALCSAKDPFTAWNLQCELREKLIAYICELEEGLGLPKDRIALESRDEPDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNA9</accession>
    <name>A0A5C6ZNA9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NAD(P)H-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_03715</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the nitroreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02149">
        <property type="entry name" value="NfsB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.109.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033878">
        <property type="entry name" value="NfsB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029479">
        <property type="entry name" value="Nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000415">
        <property type="entry name" value="Nitroreductase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00881">
        <property type="entry name" value="Nitroreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55469">
        <property type="entry name" value="SSF55469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitroreductase" evidence="2">
        <location>
            <begin position="8"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="209" mass="24105" checksum="356BA091C35C2719" modified="2019-11-13" version="1">MNIIESLQWRYATKKFDASKVLSEEKLNIIKQAFNLTATSFGLQTIKMMIVENKTMRADLLPHAFYQKQVVDASHLLVLCIQENIEEEDVDLHFNNVNYLRETPETILKPYRADLKKFMTNMSVDERQEWSVKQAYIALGNLMTVCAVEGIDSCPMEGFIPKKFDEVLNLEPKGLKSVLLLPIGFRAEDDQFATMKKVRKSEDHTIIEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNE6</accession>
    <name>A0A5C6ZNE6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_03920</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022982113" evidence="1">
        <location>
            <begin position="23"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase" evidence="2">
        <location>
            <begin position="75"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="360" mass="40151" checksum="FFD420A3B2232711" modified="2019-11-13" version="1">MKINFFYLAISLVLLHFSCSSEDDTVPTDIPSEASIYFPPLNAAETWETKSLAELQWNPSQLAPLQDFLAERNSKSFIILHNGKIVVEHYMNGHTAVTPWYWASAGKTLTSTLTGIAQDEGLLDINTKVSDYLGTGWTSSATEKEHLITSKNLLNMTSGLNDELGDGVSAENLQYVADAGTRWAYHNAYVKLQDVVAQASGQSWDAYFNTKLRDRIGMNGTWFTFGNSNVYASTTRSMARFGLLVSAKGRWEETEIVSGDFLNAATNSSQNINQAYGYLWWLNGKSTYHLPQTQLEFQGELIPNAPEDMYCALGKNDQKLYIVPSQKLVIVRMGDAGDTENFGLSDFDDQLWLRINALVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNM6</accession>
    <name>A0A5C6ZNM6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphatidylinositol kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_04340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017508">
        <property type="entry name" value="HipA_N1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13657">
        <property type="entry name" value="Couple_hipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03071">
        <property type="entry name" value="couple_hipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Couple_hipA" evidence="1">
        <location>
            <begin position="5"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="110" mass="12823" checksum="00AEF03D534E5F7E" modified="2019-11-13" version="1">MRQAKILYDNVICGLLTETDDGEFTFKYEDAYVNHYPSQFITFTMPVRNKEYKEKRLFPFFEGLIPEGWLLDIASKNWKINTNDRMGLLLACCQNCIGAVSVQPIQMKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNU2</accession>
    <name>A0A5C6ZNU2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lytic transglycosylase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_03215</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008258">
        <property type="entry name" value="Transglycosylase_SLT_dom_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01464">
        <property type="entry name" value="SLT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023134584" evidence="1">
        <location>
            <begin position="24"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="SLT" evidence="2">
        <location>
            <begin position="108"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="319" mass="36212" checksum="3407D2F8E38FC25A" modified="2019-11-13" version="1">MKNFKNILAAVGLISLSGFFIYAVQPNEQVMNLKANETQKTSTIKQGVNDYNVYAITLPENLNFAGEKIPVENPDIYERMDRELLVNTYWQSNGLLMFKRAGKYFPIIEPILKKNGVPDDFKYLAVIESGLTNAVSPAGARGVWQIMPATGRENGLEVNDNVDERYNLEKATEVACQYLKDAKAKLGSWTLAAAAYNAGQTGISRRLEEQQVNDYYDLLLGEETGRYMFRIVALKEILSHPKTYGFNFSAEDLYKEIPTYQVEVDTAVTNFASFAKLHGINYKILKIHNPWLREDHLNNSSRTKYSISIPLKGYYTEQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNY1</accession>
    <name>A0A5C6ZNY1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase M61</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_00225</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007963">
        <property type="entry name" value="Peptidase_M61_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040756">
        <property type="entry name" value="Peptidase_M61_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05299">
        <property type="entry name" value="Peptidase_M61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17899">
        <property type="entry name" value="Peptidase_M61_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022659488" evidence="1">
        <location>
            <begin position="17"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M61_N" evidence="3">
        <location>
            <begin position="35"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M61" evidence="2">
        <location>
            <begin position="316"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD91061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="628" mass="69908" checksum="7FE6087991A0AFE0" modified="2019-11-13" version="1">MKHLFSVLALSTLLFACGTKTTTNDLATANPIVTSINLSAVKDDKAPVVINPGRFTQETVTFRLPRVVQGTYSVSDFGKYIADFKAIDYDGNELTTTKTDENTWTIANATQLDQLVYSVNDTFDQETTGGIGGEQPFSPAGTNIEPDNYVLNLHGFIGYFDSLKNAQYTLDVTAPSAFLHSSAIQETNTKTSADGAQTTISYFAPRYFDITDNPMMYGKLDMEEFMVGDVKIVLSVYSPNQVHTAASMKETVYKMMEGQKAYLGDINTTPRYDIFLYLSDQGEGSPKGFGALEHHTSTVVVLPEASSKEQLAASMVDVVAHEFFHIVTPLSVHSEDVHYFDYNQPTFSKHLWMYEGVTEYFAQHFQVHQGQIEPKTFYQTITEKIQSSRQMDDSMSFTTMSENVLDDPYAKNYYNVYQKGALIGMCIDILMREESDGNRSMMSLMKELSNKYGVDKPFEDDKLIAEITAMTYPSVGAFLKTHVEGTTPIDYNEFFQKVGLEFAEAKIETNYIQNGNGFIFDGDREKGTIFFSEGVNDNSFWVEQGVKPGDVVKTVNGTALTLANAQASIGAMYQWKAGDDINVVLDRDGTEVVIKTKLTPSFTTSKTLVEIENATKAQEALRNAWLKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZP05</accession>
    <name>A0A5C6ZP05_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dephospho-CoA kinase</fullName>
            <ecNumber evidence="1">2.7.1.24</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Dephosphocoenzyme A kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">coaE</name>
        <name evidence="2" type="ORF">ESY86_01005</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>3'-dephospho-CoA + ATP = ADP + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18245"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57328"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.24"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 5/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the CoaE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.24" evidence="1"/>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00241">
        <property type="reaction ID" value="UER00356"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004140">
        <property type="term" value="F:dephospho-CoA kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00376">
        <property type="entry name" value="Dephospho_CoA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001977">
        <property type="entry name" value="Depp_CoAkinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01121">
        <property type="entry name" value="CoaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00152">
        <property type="entry name" value="TIGR00152"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51219">
        <property type="entry name" value="DPCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="11"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="196" mass="22203" checksum="E549A2BA113A76ED" modified="2019-11-13" version="1">MIVVGLTGGIGSGKTTVANFFKTLGVPVYIADDEAKKLMNSSKVIKKELVAIFGSKAYLDGLLNRDYLANKIFTDQSLLQKMNKIVHPQVAKHFKEWLKKQNSDYVIKEAAIIFEHQKQAEYDRIITVVATKEARMKRLLKRDGSSRARIEAIMANQMPDSDKIKRSHFVIENNLLEATEKQVLETHNSILESLKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZP25</accession>
    <name>A0A5C6ZP25_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein adenylyltransferase SelO</fullName>
            <ecNumber evidence="9">2.7.7.n1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">selO</name>
        <name evidence="11" type="ORF">ESY86_03590</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + L-seryl-[protein] = 3-O-(5'-adenylyl)-L-seryl-[protein] + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:58120"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:15073"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:142516"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + L-threonyl-[protein] = 3-O-(5'-adenylyl)-L-threonyl-[protein] + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:54292"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:13847"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:138113"/>
            <dbReference type="EC" id="2.7.7.n1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + L-tyrosyl-[protein] = diphosphate + O-(5'-adenylyl)-L-tyrosyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:54288"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:13846"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:83624"/>
            <dbReference type="EC" id="2.7.7.n1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the SELO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.n1" evidence="9"/>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00692">
        <property type="entry name" value="SelO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003846">
        <property type="entry name" value="SelO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32057">
        <property type="entry name" value="PTHR32057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02696">
        <property type="entry name" value="SelO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="269"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="100"/>
            <end position="103"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="134"/>
            <end position="135"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="279"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD90460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="520" mass="59664" checksum="E8968A11105803FE" modified="2019-11-13" version="1">MKLNIKNTFTKQLPADPSSENTRRQVAKACFSYVEPKATKNPKLLHVSPELLETLGISAEESESEEFLKLFTGNAVLPDTKPYAMCYGGHQFGHWAGQLGDGRAINLFEIAQNQQQWALQLKGAGETPYSRTADGLAVLRSSIREYLCSEAMFHLGVPTTRALSLALTGDLVLRDVMYDGHPGYEKGAVVCRVAPSFIRFGNFELLTSRQDDATLKQLTDYTIAQFFPQLGKPSKATYISFFEEVAKRSLEMVIHWQRVGFVHGVMNTDNMSILGLTIDYGPYGWLEAYEKGWTPNTTDRQFKRYKYGAQPDMLLWNLNQLANALYPSIEDTEGLERILNDFRDQYFAGYLKMMRSKLGLSIQEHDDAYLITDLEQHLELTETDMSIFFRNLANFSSEKPSEGLEVVQDAFYSIDEVSDKIRQQWNAWFEAYAKRLKLERNTSEDRKEKMNQVNPKYVLRNYMAQLAIDDADKGNYETIDELFKLLKRPYDEQPEHQKWFAKRPEWARHKVGCSMLSCSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZP70</accession>
    <name>A0A5C6ZP70_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Outer membrane beta-barrel protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_02325</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022705265" evidence="1">
        <location>
            <begin position="19"/>
            <end position="910"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="910" mass="102225" checksum="478B2B27B7B24239" modified="2019-11-13" version="1">MKQIAFLTFLLTTTLCTAQIIVKGVVKDSIGQPLELANIIAINTATKAMASYAITNDKGEFKLDLEKNTAYTVQVSYIGMKTFSETLSTIDTNIDKNYTLKEDNVLDEVELTYEMPVTIRGDTLVYNADSFKDGTERKLEDVLKKLPGVEINADGQIEVEGKVVTKLMVDGKDFFDGDTKLATKNIPSNAVDKVQVLKNYSEVGQLGGVTNNQDNIAINIKLKEGKKNFWFGDVTAGSGVAGTDDLYLLQPKLFYYSPKYSINLIGDLNNIGEVALTNRDIRNFGGGFRAPSQSSGTSINLGDNGLSGLTNIANAQKVVTKLAAANFSYAPKKSLDLSGFLIYNSSRLRTRQESFVQYTNSELGIPDEATVEMGREASNQGLAKLSASYKPNPNNQIDYDVLGRISDGTEAQNLFSSVVGNTNQLDKVKPFSINQNLNYYYTLNENNIFALEAQHLFKDEDPFYNAVLANDPTNNEDGPNADAFDNTAEGLGLDRNQFNYDLNQERRIKSNQLDAKLDYYHILNNVSNINFTLGTILSKQQFNSKIFQFLDDGSFFDPTPVINEGLDTNDTEYNFSDIYLGAHYRLKTGKFTITPGFSVHAYGNKNIQFGETFEDNFVRILPDFETRIQFKKSENLIFRYNMRNSFTDVTSLAQGLVLNNFNSIQFGNPELQNALSHNLNLSYFSFNMFNYTNIYAVINYNKNVDEIRNLTNFDNVIRTSTFFNSNFADESLTAFGRVQRTFGKLRASLRTSFNYSKNNQFIQGIQSVNERFVQSYTPELRTNFREAPNVSVSYNYSVSNNNQGSNATTFTTNSPTLEFDAYIWKSVTFKTDYAYTNQDNGTGQSQSFQNWNASLSYRKDRDAKLEYQVRATNLLDVDSQVSNGANAISVFSSETFIQPRFVTFRLIYTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZQ00</accession>
    <name>A0A5C6ZQ00_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Gliding motility protein GldC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">gldC</name>
        <name evidence="1" type="ORF">ESY86_01975</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019854">
        <property type="entry name" value="Motility-assoc_prot_GldC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19937">
        <property type="entry name" value="GldC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03515">
        <property type="entry name" value="GldC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="111" mass="13050" checksum="9362A523B57E9703" modified="2019-11-13" version="1">MAKTHTSKIELNVELDENRIPEKLRWSAEDGGIDNEEAKALMLSVWDSKAKESLRIDLWTKDMPVDEMKQFFHQTLVEMSNTFQRATQDEKMTATMKDFCDYFAEKLELKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZRV9</accession>
    <name>A0A5C6ZRV9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">AhpC/TSA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_01680</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025380">
        <property type="entry name" value="DUF4369"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14289">
        <property type="entry name" value="DUF4369"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="222"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="138"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD91320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="360" mass="41704" checksum="4B6F7FEEADAD4D56" modified="2019-11-13" version="1">MKKIIWSFLTALIVVSCDENREIVAYEINGTLKNIPDSSVVYISENNKYMDSTRVLNEKFQFSGNLEKPTYVRLIIKNSSDYKSFWLENNIIHFEAEKGEFKEAKITGSQTQQQRDILFGRLKVVQMEMENIEDSFVDSMTEREIDSLKNQYEFLESKEISINQEYVKEFPNSLVSSYVLSVYATSWGKEKTRALYEQFSTENKESNYGQQIAKYIELHKRLEIGEQFADFDMDDQNSGVKKLSDLKGNIILLEFWASWCAPCRLENPNLVKTYDTYKSKGFEIFAVSLDIDKNSWLEAIEKDKLNWTQVSDLKGQDNKAALIYGISAIPDNFLISENGVIIGRNLRGEELNRKLSELLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAK0</accession>
    <name>A0A5C6ZAK0_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Lipid II flippase Amj</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">amj</name>
        <name evidence="2" type="ORF">ESY86_20385</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Amj family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000070">
        <property type="protein sequence ID" value="TXD86311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015648">
        <property type="term" value="F:lipid-linked peptidoglycan transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02077">
        <property type="entry name" value="Amj_flippase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021260">
        <property type="entry name" value="Amj"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10997">
        <property type="entry name" value="Amj"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="1" id="KW-0133">Cell shape</keyword>
    <keyword evidence="1" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="192"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="237"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="265" mass="29695" checksum="7B954412192138C8" modified="2019-11-13" version="1">MTIQIIIVLLLTFIIHLISTLSYSVRIVGTRTRKIAISFALFNIMVLISRTSNSFQAPLLAKWVENNINLNLNPGTYEIRLILLAATLATIFGAFLIPTFQRILSKAVMNFSIHKSMPKLILHSFTKTGIMQIRREISIPNKENLSINSKTEFPIKIFIFNILAVAILSVGVLSSLYAGFITPELRTTASSLSAIVNGFATILMFVIIDPYLSILTDEVVEGKFAESEFRRTIRYMVFARLIGTILAQLLLVPFPHFIAFVAEII</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAK3</accession>
    <name>A0A5C6ZAK3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_20070</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000056">
        <property type="protein sequence ID" value="TXD86497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021860">
        <property type="entry name" value="Peptidase_S12_Pab87-rel_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11954">
        <property type="entry name" value="DUF3471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase" evidence="1">
        <location>
            <begin position="42"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3471" evidence="2">
        <location>
            <begin position="398"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="488" mass="56309" checksum="22F45674C013F912" modified="2019-11-13" version="1">MKKWFTTLLILSQLVLFGQSGNKEKTIEQKLKYFLELSDSLMIKTNTAGVGIAIVYNGEIIYKGGLGYRDVANKNIVTENTLFPIGSNTKPMTGIIASRLVEKGLLDWNAPVKNYYPEFKVDDNYVTENATIKDLFTHMTGVGRYDLLYYKNSSITRDEILEKLPLMKSKYPIRQQYSYNNFMYLIAGIVEEKVSGKNWGNLVKDEVFTPLHMYNSYSVFQEYLNYKERAKGYKSDGITEVDYQNIDIIAPAGSVSSTPSDMALWIKMLANKGKIDNQNYITEDQYNYYTAPHATFNPNRAISSSIGWIMGYPNGKKFIQKEGGIDGFRSKVTITEDDKFGIAIMTNNWSDYISIITDYALNIFGDDNYERDYKWEKSLEYKKTDNTEKDTKEEKPLLHKIDEYIGTYEDEIYGKITISKNKKKLQFKFHDFKSKMLHLGFDNFEVGLNLGNGSEDYILYFHTGINEKIDKIEFKLESNMPISNFNKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBW7</accession>
    <name>A0A5C6ZBW7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF3078 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_16630</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000023">
        <property type="protein sequence ID" value="TXD87519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021428">
        <property type="entry name" value="DUF3078"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11276">
        <property type="entry name" value="DUF3078"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="313" mass="36146" checksum="077EE005228C566E" modified="2019-11-13" version="1">MKRAVCILLMLTFQHFYSQNNFPEVPKDYTWLQTNQANLDISEVTFVNWNAGGSNSISALLNVLSELRYQDTYYKWRNSAKLRYGINKQENQRLRKTEDELELISTFGFRNDTLTNWYFSGRANFKTQFTNGYQYPNRDNEISKLMAPGYLFLGGGTEYGKNLEKFSVYMSPLTFKATFVLDADLSNAGSFGVTPAVIDAEGNIIKQGERVRTEMGVLFTNFYEKEIFENIRVRHNLSLYSDYINNFGNIDVDWEVVFDFRVNQYVKATLGSHIKYDNDIKILEETAVEDEFIENGAKVQWKQLLGVGVVVGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC25</accession>
    <name>A0A5C6ZC25_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_20090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000057">
        <property type="protein sequence ID" value="TXD86479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="76" mass="9043" checksum="0586B16DCB898363" modified="2019-11-13" version="1">MYKIAGIFEVEVSELLEIKATNQFNQTNKESATAYLQQTANFYQENKEQNQKIIELYESRLKDKDRLIEQLEKLIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC49</accession>
    <name>A0A5C6ZC49_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000084">
        <property type="protein sequence ID" value="TXD86196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="25"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="287" mass="34847" checksum="0A5E5A4E72166CC7" modified="2019-11-13" version="1">MRIILILILFTILSCSDNKTDFEKHNELDQKAMVQFKDKEFEKALLNFEKAIDLKPTQDVSIYFYATASALNAKKNDKAKELLIASIHNTNTSKEYFLNFPEFDKFREEKLFSEIENDYEKHISEFYNKLEYPEIYREVDSLMEIDQEYRTNGSEWNEISRIDSLNINRLIEITKEYGWQKKGWLVLWHQRGTYGQDNYVWNFFKPYIDEQIKNDKINKDFWVMFEEERSIVKKKEQIYGMYWSQYDEYPIIDIENVDKRRAKFDVPPLWYMEKVYGIKLPAEYKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC91</accession>
    <name>A0A5C6ZC91_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">SusC/RagA family TonB-linked outer membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_19530</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000042">
        <property type="protein sequence ID" value="TXD86711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023996">
        <property type="entry name" value="TonB-dep_OMP_SusC/RagA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023997">
        <property type="entry name" value="TonB-dep_OMP_SusC/RagA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04056">
        <property type="entry name" value="OMP_RagA_SusC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04057">
        <property type="entry name" value="SusC_RagA_signa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023068120" evidence="5">
        <location>
            <begin position="24"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="7">
        <location>
            <begin position="115"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="6">
        <location>
            <begin position="476"/>
            <end position="1028"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD86711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1030" mass="111270" checksum="20409E265917CEE6" modified="2019-11-13" version="1">MKQNLLQKVAYGFFFLLAGIMHSQTVSGIVSDNSGPLPGVNVLVKGTANGTQTNFDGEYILNNVPSDGVLVYSFVGFKTQEVNVGGRDKIDITLAEDAALLDEIVLIGYGTTTIKDATGSISTVTAEEFNGGVISSPEQLIQGKTAGVQITQSSGEPGAGVAIRIRGTSSLSADNNPLFVVDGIPLSTGGTAGGADLGGGTSSARNPLSFLNPNDIATMTVLKDASATAIYGSRGSNGVVIITTKSGQKGGGGVFELNSNTSFSRALKRFDLLEGPQYLNAITQFGGNAEALNFGSNTDWQDVILRDVFSTDNTFAYSNNYGDGYVRGSIGLFDQQGVVENSSQERLTGRVNASHRFFDDKLKVDINATLSKIDDESPYITNSAGSQGDLLGATYFANPTWPNTVEFTSGDGKLNPRQLLTYYQDLNETNRTLLNGAAEYSILSNLKAKVNLGYDKSESTRTQVISPDIDGFNNGATGNGRAALQDVNVENQLMDLTLNYTKEFKNSSLEVLLGYSYQSFQNSGRTVLGYGMNSNNLGQIATNLENAANIIEGSIGGTPFQQYGFSSAGLFINQILPTINGNVEIGAPSGVPVNTVTGNTFDFTDELQSYFTRVNYKLGDKYLFTFTLRADGSSRFGPDNQYGYFPSGAFAWQLHKEDFIPEAFSNLKLRLSYGKTGNQDALGYGNFIQRQRFGDPGIGNGGEVQFGSAGIISNEDSSLQWEETLQSNIGFDYGFFNDRLSGSIDLYHKSTTNLILQQLTAQPAINPFRFSNVDADIINKGIEFAINYDIIQQEDMNWNFGFNVAYNENEVQNFDGLIQTGEINGNGLTGAFAQLLAEGQPLYSFFLRDFAGFDENGISIYPNGDQQEFVGKSALPDIIVGINTSFSYKNWDVNAFLNGQYGQYIYNNTANAFFTAGIIGSGQNVTQNVLSSGESTANAPDVSTRFLEKGDFLRLQTASIGYRLNLEDNSFFKSVRLSITGQNLFVITPYSGLDPEVDTPSGLNNIPSFGIDYTSFPRPRTFTFGLNANF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCC6</accession>
    <name>A0A5C6ZCC6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SDR family NAD(P)-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000030">
        <property type="protein sequence ID" value="TXD87056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="249" mass="27155" checksum="72F513DBCB5B67AA" modified="2019-11-13" version="1">MKKIALITGATSGIGRATAYELAKHNINLILCGRRQERLVAIQKELGSQVKVHTLNFDVRDKKATLEAIASLPEDFKTIDILINNAGNAHGLDPIQDGDLDDWDAMIDINVKGLLYVSKAVIPQMTQRKSGHIINIGSSAGKEVYPKGNVYCGSKHAVLAITEGMRIDLNPFGIKVAAINPGLVETEFSEVRFKGDKKANEVYKGYKALQPEDVAEVIYFAISRPPHVNIADVLVFCTAQANSTTLNKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCT5</accession>
    <name>A0A5C6ZCT5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosomal RNA large subunit methyltransferase H</fullName>
            <ecNumber evidence="1">2.1.1.177</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">23S rRNA (pseudouridine1915-N3)-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">23S rRNA m3Psi1915 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">rRNA (pseudouridine-N3-)-methyltransferase RlmH</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1 2" type="primary">rlmH</name>
        <name evidence="2" type="ORF">ESY86_17250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>pseudouridine(1915) in 23S rRNA + S-adenosyl-L-methionine = H(+) + N(3)-methylpseudouridine(1915) in 23S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42752"/>
            <dbReference type="Rhea" id="RHEA-COMP:10221"/>
            <dbReference type="Rhea" id="RHEA-COMP:10222"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:74486"/>
            <dbReference type="EC" id="2.1.1.177"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RNA methyltransferase RlmH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.177" evidence="1"/>
    <dbReference type="EMBL" id="VORO01000026">
        <property type="protein sequence ID" value="TXD87309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070038">
        <property type="term" value="F:rRNA (pseudouridine-N3-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd18081">
        <property type="entry name" value="RlmH-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00658">
        <property type="entry name" value="23SrRNA_methyltr_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003742">
        <property type="entry name" value="RlmH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33603">
        <property type="entry name" value="PTHR33603"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02590">
        <property type="entry name" value="SPOUT_MTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004505">
        <property type="entry name" value="MT_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="1">
        <location>
            <begin position="124"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="157" mass="18109" checksum="E10D6BDF55A0EBD9" modified="2019-11-13" version="1">MTIKLLAIGKTDNKDLQKLIADYQKRLGFYIKFDFEIIPDLKKAKNLSEAQQKQKEGELILGKLNPTDILILLDENGKQIDSVAFSNYLQKHMNSGIKQLVFVIGGPYGFSEDIYLKANGKLSLSKMTFSHQMIRLFVIEQLYRGFTILRNEPYHHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCW5</accession>
    <name>A0A5C6ZCW5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Carboxypeptidase-like regulatory domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_18795</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000034">
        <property type="protein sequence ID" value="TXD86919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="346" mass="39666" checksum="713B534E7DD26E36" modified="2019-11-13" version="1">MAIVKNSYLVVILFLCGLVTSAQTITGLVLDHSNEQPLESVSIYYDGTTIGAVTNQEGYFTITSQIKTNAIVVVSYIGYETKYFSQTELANAKTIYLNEKAEALDPVIIEPDDWSRAKKLKYFRREFLGRGEAAEACKILNEDQIQLVYSKSKNTLYAYCDQPVQIKNKHLGYRLNYKIVDFEVRFVDNRSGLIFVQGVYFAGTSNFSELNPKRIKKRYRKTREEEYHGSLLEFMRALSQKKLKEYQFSTFIKSEGSRFFVPVDPYQYLIVQKQEGDLCKVTIKTDKLVVLNNQDAQSALLPVEGFDTFYIDAYGIHSPPDKLLFSGVFGNERMAKLLPLDYKVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD31</accession>
    <name>A0A5C6ZD31_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_15715</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="76" mass="8914" checksum="0DB82CDE715D10AC" modified="2019-11-13" version="1">MEYLTFTIDVLLVLDRAEFKLYTDKILIEPLNEIGFDDLEITLKIINKEETKSAVERELIFNTTQNFMGLTCVHIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD75</accession>
    <name>A0A5C6ZD75_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glutamate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_15230</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="274" mass="31235" checksum="01E94A191BBA30BF" modified="2019-11-13" version="1">MTLNFKPVTVMLFALVLGINEGFAQFGFTNEIGIVAGPVAFQSDFGERQDFETNSGNTGYGIGLVHYINFTYRRQYSSRQSANFFNYHFKVRNELSFNKTNLDHFGKWVDEDRKSTNADKLRQHSGSAQNINIGSQLEFFPLSIRDFEALSYSFAPYISLGVQFTAYNPKVFTTFGDGNIDNSNNFYDSWVQATNPNFNEDNFLFDGAGSTFSVVGGVGTRYKLNLLSDLVIDLKWQYFLDDRVDGLDHNLESNKSNDWLVWLNIGYIHYLNSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDH4</accession>
    <name>A0A5C6ZDH4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplW</name>
        <name evidence="6" type="ORF">ESY86_14840</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01369_B">
        <property type="entry name" value="Ribosomal_L23_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_L23/L15e_core_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013025">
        <property type="entry name" value="Ribosomal_L25/23"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11620">
        <property type="entry name" value="PTHR11620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00276">
        <property type="entry name" value="Ribosomal_L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="SSF54189"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD87943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="96" mass="10640" checksum="889BD0E4F15D1B69" modified="2019-11-13" version="1">MSILIKPIITEKATTKSELNNCFTFQVNTKANKVEIKKAVEAAYGVSVEKVRTINVRPDRSTKFTKTGVQHGKTNAVKKAIVQLAEGEEIDLYANM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDK0</accession>
    <name>A0A5C6ZDK0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_14415</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="71" mass="7731" checksum="51906CC9A20B864E" modified="2019-11-13" version="1">MLFKIKDMLDSILNKKEFKPLTRKELQIIVGGGTCTLTATNGLKVVVPDREGDSGYCKRLCDNAPGCASVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDR3</accession>
    <name>A0A5C6ZDR3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">YceI family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_16390</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007372">
        <property type="entry name" value="Lipid/polyisoprenoid-bd_YceI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036761">
        <property type="entry name" value="TTHA0802/YceI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04264">
        <property type="entry name" value="YceI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00867">
        <property type="entry name" value="YceI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101874">
        <property type="entry name" value="SSF101874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022916957" evidence="1">
        <location>
            <begin position="23"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="YceI" evidence="2">
        <location>
            <begin position="26"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="190" mass="20854" checksum="DD389CFA7F1F34D1" modified="2019-11-13" version="1">MKKTIFKSAAVLALTITLVSFTSLSEKKIKTEESSVTWKGHKVTGSHEGNINLSEGTLLFEGETLTGGNIVIDMSSISVTDLETGDGKEKLEGHLNSDDFFGTANHKTANFKMTKVTGKAGNYKVTGDMTIKGITHPLSFDMMVNNNTATANLKVDRTKYDIRYGSASFFDNLKDKAIYDEFDLMVSLKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDW3</accession>
    <name>A0A5C6ZDW3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RagB/SusD family nutrient uptake outer membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_18595</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SusD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000032">
        <property type="protein sequence ID" value="TXD87000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033985">
        <property type="entry name" value="SusD-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012944">
        <property type="entry name" value="SusD_RagB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14322">
        <property type="entry name" value="SusD-like_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07980">
        <property type="entry name" value="SusD_RagB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="SusD-like_3" evidence="6">
        <location>
            <begin position="30"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="SusD_RagB" evidence="5">
        <location>
            <begin position="327"/>
            <end position="466"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD87000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="466" mass="52918" checksum="61F6B3EF35BF057E" modified="2019-11-13" version="1">MNFIHLNLRNYPLIVFLAICLTSIAISCEDFVEVDPPNNQLTGETIFSNATTANTAFVNIYGKLRDNALTTGGLAGLPYLMGLYTDELELFNQNLQQQEFYSNNVTPSNFLIQNLWNESYNLIYATNTIIKGVENSNSLSLEDRERFLGEAYFTRAFIHFYLVNSFGTIPYIKTTDFLINKNVTRDDIGSVYQNIIDDLILSRSLLSQNENTSITNLRPNQFTASALLSRVYLYTEQWQLALNESEALIANSNYTLNTDTEQVFFKTSNETIWQYDSGQSSSNTLDAQTYIFTSSPPPNSALAPNLVNSFEPNDQRFTDWLGSVSAGTDIWYYPFKYKLNTVTSATQECTIVFRLAEFYLIAAEANAQLGAISNGLNRLNAIRTRANLEPVTSTNTNSLLNAIYRERKIELFTEMSHRFFDLKRTGRIDEQLSQIKPNWQSTDKLLPLPESELILNTNLLPQNDGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE05</accession>
    <name>A0A5C6ZE05_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UvrABC system protein C</fullName>
            <shortName evidence="6">Protein UvrC</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Excinuclease ABC subunit C</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 10" type="primary">uvrC</name>
        <name evidence="10" type="ORF">ESY86_13785</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Interacts with UvrB in an incision complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the UvrC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009380">
        <property type="term" value="C:excinuclease repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009381">
        <property type="term" value="F:excinuclease ABC activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00203">
        <property type="entry name" value="UvrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035901">
        <property type="entry name" value="GIY-YIG_endonuc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001943">
        <property type="entry name" value="UVR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036876">
        <property type="entry name" value="UVR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004791">
        <property type="entry name" value="UvrC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001162">
        <property type="entry name" value="UvrC_RNase_H_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038476">
        <property type="entry name" value="UvrC_RNase_H_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01541">
        <property type="entry name" value="GIY-YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08459">
        <property type="entry name" value="UvrC_HhH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00465">
        <property type="entry name" value="GIYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46600">
        <property type="entry name" value="SSF46600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82771">
        <property type="entry name" value="SSF82771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00194">
        <property type="entry name" value="uvrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50165">
        <property type="entry name" value="UVRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3 6" id="KW-0228">DNA excision</keyword>
    <keyword evidence="5 6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4 6" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="GIY-YIG" evidence="8">
        <location>
            <begin position="15"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="UVR" evidence="7">
        <location>
            <begin position="207"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="UVRC" evidence="9">
        <location>
            <begin position="268"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD88166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="597" mass="69336" checksum="2055C91B469F0BF9" modified="2019-11-13" version="1">MQKPTLDIQIKTLPHQPGVYQYFDTEDKLIYVGKAKDIKKRVSSYFTKTHDNGKTRVLVRKIASIKHIVVETETDALLLENNLIKNYKPKYNVLLKDDKSYPWICIKKERFPRVFPTRRIFKDGSEYYGPYTSMKTVRTLLDLIKGLYPLRTCNYNLSEEKIETGKYKVCLEYHLGNCKGPCEDLQTEKDYNDSIKAIREIIKGNFKDSLSQFKTQMKDLAANMQFEDAQHIKDKIEVLENYQAKSTVVNPKISNVDVFSIMSDEGYAYVNFLQLSYGSIIRSHTLEIKKKLDESDKQLLKLAITEIRQRFNSNSKEVYVPFKMDLGEDLKVTVPQLGDKKKILDLSLRNAKYYRMERFKQVKIVDPDRHANRIMAQMKKDLRLREEPRHIECFDNSNIQGTNPVAACVVFKDGKPSKKEYRHFNIKTVVGPDDFASMEEVVYRRYKRLLEEEQPLPQVIIIDGGKGQLSSALKSIDMLGLRNKIVVIGIAKRLEELFYPDDPIPLYLDKKSETLKVIQHLRNEAHRFGIEHHRNRRSKGALTTELETIEGIGEQTVVALMKKFKSLKRIKEAPKKDLEAVVGLSRAQKIRAFYDKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE92</accession>
    <name>A0A5C6ZE92_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phytoene desaturase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">crtI</name>
        <name evidence="5" type="ORF">ESY86_15515</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1 3">Carotenoid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the carotenoid/retinoid oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016117">
        <property type="term" value="P:carotenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014105">
        <property type="entry name" value="Carotenoid/retinoid_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02734">
        <property type="entry name" value="crtI_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0125">Carotenoid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amino_oxidase" evidence="4">
        <location>
            <begin position="12"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD87873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="501" mass="57315" checksum="265DDFF14A39D20A" modified="2019-11-13" version="1">MKKKIIIIGSGIGGLGAAALLAKSGYEVTVIEKNANLGGRANIFEAEGYTFDMGPSWYLMPDVFEQYFKLLDEDVSKHLDLIKLSPSYRVFFSNDEELPIVDIHSDLDKDLPLFEQLEPGITPKIKEYLKRSGEQYEMAKDTFMYRNMGFSLDFLKWDVIKKGIELNPFQTMQSYLNKWFQSERVKKILEYTLVFLGSDPSKTPAMYNIMNAIDFNMGVYYPKGGIYEIVKALVSINKKHGTQFMTNSPVSKIRVENKKATGVLLENGTVLEADMIISNADLWFTETHLLEKRHQTYPEKYWEKAVLSPSAFIMYLGLDRELEVLSHHNLRFGGDWKQNFKELFDTPQLPEDPSYYICKPTETDPDLSPAGTDNLFVLVPIPPGLTLSEADMASYRQKILNLMKTDLKLPAFEDYIVYERSYWSDDFRRDYNAYKGTALGMAHTLKQTLKRPLNYSKKVKNLYYVGAGTSPGIGMPICLISAELVYKRIQKIKTSKPLKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEG0</accession>
    <name>A0A5C6ZEG0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4197 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_16595</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000023">
        <property type="protein sequence ID" value="TXD87512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025245">
        <property type="entry name" value="DUF4197"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13852">
        <property type="entry name" value="DUF4197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022666213" evidence="1">
        <location>
            <begin position="19"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="235" mass="25817" checksum="CD3236B0EFA0AA7B" modified="2019-11-13" version="1">MYKKFILLVCIFNLTACAELQSVVDQLPQGGGVLSNADIAAGLRQALDQGIEQQVTKLTKPDGFYKNDLVKILLPEELQKVDKGLRDIGLGSLADEGLKVLNRAAEDAVGEATPIFVNAVKQISFNDAKTILLGQDDAATQYLTAKTQTELYNKFQPVINNSFTKVGADQIWSNLITKYNAIPFTSDVNPDLTDYVTGEALKGVYKMIAVEEKDIRTKLSSRGTDLLRRVFALQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEI1</accession>
    <name>A0A5C6ZEI1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="520" mass="58535" checksum="626D0A008B8586C2" modified="2019-11-13" version="1">MSKKTKKTLAIVGIIAVVLIICFLIANYFAKQKLESMVANLPENIQLQYEAADISVLSGSVTLEKPLLSIKGKTTQSTNAKIKLESFTIEDLSYWDLIFNANINLDRIVLNAPEITYFHNKLIKNEAYKGSGNAKLKQDVNVKSFEILNASIEVFDQASDSLIFKTNNLEFKLEGISVNAETLASKLPLEFKDLTFSTKNLKFQTNEFDDLYVDSISVTKTHSKFSGVAIKTKYSKSELSQRIKKERDHFDVTIASAEVFEQDAGFHGDSIFDFRSKKVLINGLKLNVYRDKLVADDPTRKDLYSKMLRELKFNLALDELLIEESSILYEEKVKQDKPAGELQFGQLEASMLNVGNTYEAPVEIEISTNFMKSTPLKVNWDFDVQDVNDHFIFKADLGLLKAEDLNPFMTPNLNITLDGELNKTFFTIDANANTGSIDLKTDYAQFDINILKGDGKDKNKLLSGIVNLFVAKTSQKKEDDYRYGNAENVERDKTKSVFNFVWLNAKSGLLSAMTGGGKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEP9</accession>
    <name>A0A5C6ZEP9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_17610</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000027">
        <property type="protein sequence ID" value="TXD87251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032465">
        <property type="entry name" value="ACMSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240">
        <property type="entry name" value="PTHR21240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="2">
        <location>
            <begin position="25"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="301" mass="34726" checksum="3DDC6F1FE8C46FBC" modified="2019-11-13" version="1">MNRSIIVLLILVHQFLSVQSQTRIIDMHLHCYSPEVLAEERYDHYGVKGEQDLETHFQETYAAMKKYNIVKAVVNGMPGTVEYWMSNDTDNRLIQGLHFMHPDELKMNITEFETLIKSGKVKVLGELGPYYSGTTLSDAVWQPYLKICEKYDIPVAVHTGGGDPGGTYTWAPKSRLSLGDPYLIEDVLVNYPKLRIYMMHAGGEDWPERAIRLMAYYPQLYTDIAVMLWVEPNTQRYIKEFLKNIKEAGYLNRVMFGSDQMMWPYAVGKSIDFLNSIDFLTAQEKEAIFYNNAATFLKLKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEQ9</accession>
    <name>A0A5C6ZEQ9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RagB/SusD family nutrient uptake outer membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_16135</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SusD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000021">
        <property type="protein sequence ID" value="TXD87679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033985">
        <property type="entry name" value="SusD-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012944">
        <property type="entry name" value="SusD_RagB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14322">
        <property type="entry name" value="SusD-like_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07980">
        <property type="entry name" value="SusD_RagB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022853700" evidence="5">
        <location>
            <begin position="22"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="domain" description="SusD-like_3" evidence="7">
        <location>
            <begin position="103"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="SusD_RagB" evidence="6">
        <location>
            <begin position="269"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD87679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="512" mass="57484" checksum="27F3FE04C5A882BD" modified="2019-11-13" version="1">MKNVKLLFQPLVLLLASSMLLVTCSDKLEENDGQLAADDLDYTNMNDMVLPLYGAYSATYTRGWEDPLLLGVRGDDVNAGGLDDQPLFAETDLYNYDKTFWMFNQVWNNFYSDLAVIINTAEIVERYKEFATGNNIARADQYIAETKVLSAYQHLNMARLWGNIFIIESTRFDEEVSNGVDTKEEVMQYVSDLMDEAIPFLPDVRPNERTDIPGGVTKYTALALKAMANQELENYQEVANATGQIINSSKFMLFNDFYELFKKPGKLSNESLFELQFSDFNQASGATENHLYAPFGPSNWTPVVEGASNGWGFYEPSLKYIKFMLDRGETVRLETSVLFTPDGIAEIQSDPAYTNLPNLVSNTTPDGDVINNYVRANFASGKHYLPSNQLTEGRNAYGSGKNFLVIRYSEILLMYAEARTRGASGTGMSADEAVNMVRSRANMPALSGVTTAQVLNEKFAELAMEWGIRYFDMIRVNDYSELSYEGRTFSADKELLPYPQAQLDLLPLGSNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZER0</accession>
    <name>A0A5C6ZER0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyl carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_13100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="2">
        <location>
            <begin position="4"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="1">
        <location>
            <position position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="84" mass="9575" checksum="F4FFDCBE47958BA3" modified="2019-11-13" version="1">MTKDELISKLKAIVKPYVQDEEALEKLSEDTDFISDLKINSANLVDVILDVEDEFDIRIENDDMEKMTNVKAAMAIVNEKLAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEY4</accession>
    <name>A0A5C6ZEY4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cycloisomaltooligosaccharide glucanotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_12825</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 66 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14745">
        <property type="entry name" value="GH66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025092">
        <property type="entry name" value="Glyco_hydro_66"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13199">
        <property type="entry name" value="Glyco_hydro_66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="586" mass="67019" checksum="21DB9BA8716E0CD8" modified="2019-11-13" version="1">MKNFQLKYVQTVKAIFVLLLLVSCDSDDDAINSNLEIQSPSLSYNEVLNLSKDKAKYNAGQEVNFRVNAVHPNTTIRYKHLGETILESPLTSTSWSWTPPMDDFKGYMVELVKNTNGDETVLGTVGVDVSTDWTKFPRYGFLSNFGNISEAERNAVLENLKNFHINGLQFYDWHYKHHIPLPVDTNGNAENSWLDLFNREVTYETVDGYINKGHELNMASMFYNLMFGAWKPEEGDGFSNQWLLYNDQLHNNINAHDLGDFGDILVTNPANQDWQNYIFSKTEHVYQNLDFDGWHLDQLGNRGNVYEYGGYQVNMPNAYQDFMMAVTEAFPNKNHVLNAVEQYGQDKILSTPVNFAYSEVWDRVQYADLVEVIMENNQMSNNELNTVLAAYMNYESSEGSFNTPSVLLTDAVIFAFGGAHLELGEHMLSREYFPYNNLSMDAELKNRLMEYYDFMVAYENLLRDGGSYTLPNVSSSDLGVNNWPPVFGNASVVSRKVEDREVFQLLNFNGVSTLSWRDNAKIQTKPNASQDFEITIATNMTVSKVWFASPDYKGGASQELEFQSNQGQITIKVPYLEYWSMLVFEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEZ1</accession>
    <name>A0A5C6ZEZ1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF1206 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_15690</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009597">
        <property type="entry name" value="DUF1206"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06724">
        <property type="entry name" value="DUF1206"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="181"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="227"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1206" evidence="2">
        <location>
            <begin position="12"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1206" evidence="2">
        <location>
            <begin position="185"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="257" mass="27866" checksum="BBDCB9EACE51F56D" modified="2019-11-13" version="1">MDSKIKKVAKSGYVSKGVVYFLTGVLAFGAASGLGGSSEGKLGVLEFLQKQAFGNVLLGIMGLGLLCYSFWRFYESIIDPEDIGSDAKGIGKRVGFFISALVYLGLGVFSIYQIVKPSGGGGNSKAKMIPLEVLPYVFYAVAAGLALKAVFQIVKAYKGDFLGKFQLESLSNINTRKTIKWLGYAGLVSRGIVVAIISYFFFRAADTASTQDIKGTSEAFAFMRESYGPWLVATVAMGLICFGLYMFIMAKYRKFQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEZ9</accession>
    <name>A0A5C6ZEZ9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_15720</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="223" mass="25563" checksum="36C5123DE233923D" modified="2019-11-13" version="1">MAYPDGSATHIGVEYQCWFLALQISFSFFEPDRIIYPEAFITDVSIIDDIKVVENGVTTFYNVKHISPAKSMHWNISELVSNCVVKHIKQQYEVDRKAKIVFVSQSDCYLITEVFQRAVNAITVNDLDMVLASKRCIENWESAKEVFDYDDQTLLGLAQNVSMRCLPLYEIKKLIEHRFTTLGHHKNLANLFVAKSLECSGRKTRITKGLINGWLLECGINFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF41</accession>
    <name>A0A5C6ZF41_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Regulatory protein RecX</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_15185</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RecX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006282">
        <property type="term" value="P:regulation of DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003783">
        <property type="entry name" value="Regulatory_RecX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33602">
        <property type="entry name" value="PTHR33602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02631">
        <property type="entry name" value="RecX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD87816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="157" mass="18977" checksum="BDD8D57F96EAFC68" modified="2019-11-13" version="1">MNTQKSYTVDEAQKRMEHYCAYQERCHKEVNQKLYDMRMIPEARDQIIVHLLDHNFLNEERFAQAFARGKFRIKKWGKQRIQIELKRKDISKIIIKTALKEISDADYYSTFDALAEKKVHTIMESNPYKKKKKLADYLLYRGWESHLVYDKVNELVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF50</accession>
    <name>A0A5C6ZF50_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cystathionine gamma-synthase</fullName>
            <ecNumber evidence="4">2.5.1.48</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_15235</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.48" evidence="4"/>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003962">
        <property type="term" value="F:cystathionine gamma-synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102028">
        <property type="term" value="F:cystathionine gamma-synthase activity (acts on O-phosphohomoserine)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00614">
        <property type="entry name" value="CGS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808">
        <property type="entry name" value="PTHR11808"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00868">
        <property type="entry name" value="CYS_MET_METAB_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD87826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="379" mass="41373" checksum="8D46298B7C5D185A" modified="2019-11-13" version="1">MKFNTKTIHGGQSPDPAYGAVMPPIYQTSTFAQTTPGGHKGFEYSRSGNPTRSALENAFASIENGEHGLAFGSGLAAIDAVIKLLETGDEVVSTSDIYGGTYRLFTSIFEKFGIKFHFIGMEDAENIEHYINDKTKLIWVETPTNPMMNVIDIKATAAIAKKHKVLLAVDNTFATPYLQQPLDLGADIVMHSATKYIGGHSDLIMGALVVNDKDLADRLYFIQNASGAICGPQDSFLALRGIKTLHVRMQRHCENGKAVAEYLNQHPKIENVYWPGFESHPNHEIAKAQMKDFGGMVSFTTKGNNYEEAIKIVENLKVFTLAESLGGVESLAGHPASMTHASIPKEEREKTGVVDSLIRLSVGIEDEDDLIADLKQAIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFB4</accession>
    <name>A0A5C6ZFB4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sensor histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_14635</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010559">
        <property type="entry name" value="Sig_transdc_His_kin_internal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06580">
        <property type="entry name" value="His_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022758261" evidence="4">
        <location>
            <begin position="23"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="478"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="160"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="230"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="His_kinase" evidence="5">
        <location>
            <begin position="513"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="434"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF06580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD87904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="718" mass="82303" checksum="7EE20A58A61F519D" modified="2019-11-13" version="1">MKSISKYLFVLLFLFAFGNLDAQQGNTRKEAPEYSITGSVRERYTYKPIPKVNIEINGGAYTRTNFDGSFLIRAKKGDELVIRHKDFETVYYTIESDDRIILEVEPAAETELKAKDYKRDIKSFNALMDSVAKYKKGDVEKSIAYVGEALSQSSSQQQNAEAYLLLAEVYMYWKQYDLAVSNYRVSLQNTETNQAKLGLGKAYELNKNYQESLETYSAIDKKNLSNYQSIILYEGLGDTYANIKNYEAAISNYKNGLEIAKNALISPKEVDLNSKLAQVYNASGKAGKAEEFFGNAMDLASKQTKKRALEEKETVADFRNNNRNYSQEIELRKEIVKDVAEAERDSVIDNASALTSQKQNYKIGNAYFLQQNYAEAIPYLEKSIKEADAKADLVVKKDATRKLSDLYVSAGDFEKAKAAFEDYKLVVDELYLKREQELSQADRFRRNIREQQNRITSLESDRKLTSSLANERSKNQQLIIYSLIAATILLCVTAFFMYKYIKQQRLANNLLALKSLRSQMNPHFIFNALNSVNSFIAINDERTANKYLSDFSQLMRAVLENSEEDFIPLQKEIELLQLYTKLEHFRFKDKFDYEIKIDDDVDVAAYQIPPMLLQPYIENAVWHGLRYKTEKGKLQILIENKTVDEITISVLDDGIGRARSKALKTENQQKQNSKGMGNIKKRVAILNDMYKDKVDVAITDYHEEEDAGTKVVVTLRKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFC0</accession>
    <name>A0A5C6ZFC0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_16905</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000024">
        <property type="protein sequence ID" value="TXD87458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="61" mass="6985" checksum="7F00C8D3D5C8B306" modified="2019-11-13" version="1">MSVFCCLFSVFCCLFSVVCCVLCVVCCVLCVVCCLVKSKFENKSQLHHSLFIIRYSTFKNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFE2</accession>
    <name>A0A5C6ZFE2_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 25">Na(+)-translocating NADH-quinone reductase subunit F</fullName>
            <shortName evidence="25">Na(+)-NQR subunit F</shortName>
            <shortName evidence="25">Na(+)-translocating NQR subunit F</shortName>
            <ecNumber evidence="6 25">7.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="24 25">NQR complex subunit F</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="23 25">NQR-1 subunit F</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="25" type="primary">nqrF</name>
        <name evidence="28" type="ORF">ESY86_16500</name>
    </gene>
    <organism evidence="28 29">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="28 29" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="28 29">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 25">NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 25">
            <text>a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:47748"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="7.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="25">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="25">Binds 1 [2Fe-2S] cluster.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 25">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5 25">Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="25">Cell membrane</location>
            <topology evidence="25">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 25">Belongs to the NqrF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="28">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.1.1" evidence="6 25"/>
    <dbReference type="EMBL" id="VORO01000023">
        <property type="protein sequence ID" value="TXD87494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016655">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00430">
        <property type="entry name" value="NqrF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010205">
        <property type="entry name" value="NqrF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000044">
        <property type="entry name" value="Cis_Diol_DH_RD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01941">
        <property type="entry name" value="nqrF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 25" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="9" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="8 25" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="13 25" id="KW-0274">FAD</keyword>
    <keyword evidence="10 25" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="19 25" id="KW-0406">Ion transport</keyword>
    <keyword evidence="15 25" id="KW-0408">Iron</keyword>
    <keyword evidence="16 25" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="21 25" id="KW-0472">Membrane</keyword>
    <keyword evidence="12 25" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17 25" id="KW-0520">NAD</keyword>
    <keyword evidence="29" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="18 25" id="KW-0915">Sodium</keyword>
    <keyword evidence="22 25" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="14 25" id="KW-1278">Translocase</keyword>
    <keyword evidence="25" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="25" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="25" id="KW-0813">Transport</keyword>
    <keyword evidence="20 25 28" id="KW-0830">Ubiquinone</keyword>
    <feature type="transmembrane region" description="Helical" evidence="25">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="26">
        <location>
            <begin position="40"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="27">
        <location>
            <begin position="135"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="binding site" evidence="25">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="25">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="25">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="25">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00019729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="ARBA" id="ARBA00023075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="ARBA" id="ARBA00030032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="ARBA" id="ARBA00030787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="25">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="26">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="27">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="28">
        <source>
            <dbReference type="EMBL" id="TXD87494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="29">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="435" mass="48641" checksum="E27749264565F418" modified="2019-11-13" version="1">MILAAGTLGTVVATVAAFLLITLLLVSLLLFVKQKLSPSGPVTIKINGEKEIEVSSGGTLLSTLSGNKIFLPSACGGGGTCIQCECHVLSGGGEALPTETPHFSRKELKDGARLSCQVKVKQDMEITIPEEVFGIKKWDATVVRNYNVASFIKEFVIEIPEDMNYKAGGYIQIEIPKCEIKFEDMDITAHPEEHETPDKFKAEWDKFALWPLVMKNTETVERAYSMASYPAEGREIMLNVRIATPPFDRNKNGWMSVNPGIASSFIFAQKPGDKVVISGPYGEFFINESESEMLYVGGGAGMAPMRSHLYHLFKTLQTGRKVTYWYGGRSKRELFYLEHFRELERDFPNFKFYLALSEPAEEDNWKVKENIDAPGDGFVGFIHNCVIDNYLNHHDAPEDIELYFCGPPLMNQAVQKMGEDFGIPDEHIRFDDFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFH8</accession>
    <name>A0A5C6ZFH8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RES domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88614.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014914">
        <property type="entry name" value="RES_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08808">
        <property type="entry name" value="RES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00953">
        <property type="entry name" value="RES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RES" evidence="1">
        <location>
            <begin position="14"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88614.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="151" mass="17698" checksum="0380FAAF2F1E5AA8" modified="2019-11-13" version="1">MEVYRISHKKHSKALSSSGAANRWNLDGEYVIYTGASRSLSTLELVVHRNTIKKLPDYELMILSIADEEDLFEQVPVKNLPNTWRSFESYYKLQLIGSAWYTEQRSLILKVPSAVIPQEYNYIVNSKHPLFTEKVSLIRNEDYFFDDRLFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFP1</accession>
    <name>A0A5C6ZFP1_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">tRNA N6-adenosine threonylcarbamoyltransferase</fullName>
            <ecNumber evidence="6">2.3.1.234</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">N6-L-threonylcarbamoyladenine synthase</fullName>
            <shortName evidence="6">t(6)A synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">tRNA threonylcarbamoyladenosine biosynthesis protein TsaD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">tsaD</name>
        <name evidence="8" type="ORF">ESY86_10495</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>adenosine(37) in tRNA + L-threonylcarbamoyladenylate = AMP + H(+) + N(6)-L-threonylcarbamoyladenosine(37) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:37059"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10163"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:73682"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74418"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.3.1.234"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="6">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the KAE1 / TsaD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.234" evidence="6"/>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061711">
        <property type="term" value="F:N(6)-L-threonylcarbamoyladenine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01445">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000905">
        <property type="entry name" value="Gcp-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017861">
        <property type="entry name" value="KAE1/TsaD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017860">
        <property type="entry name" value="Peptidase_M22_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022450">
        <property type="entry name" value="TsaD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735">
        <property type="entry name" value="PTHR11735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735:SF6">
        <property type="entry name" value="PTHR11735:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00814">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00789">
        <property type="entry name" value="OSIALOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00329">
        <property type="entry name" value="gcp_kae1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03723">
        <property type="entry name" value="T6A_TsaD_YgjD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01016">
        <property type="entry name" value="GLYCOPROTEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 6" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TsaD" evidence="7">
        <location>
            <begin position="27"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="140"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="281"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="309"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD88917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="340" mass="36850" checksum="F715C1E27793605B" modified="2019-11-13" version="1">MSSQKIYILAIESSCDDTAAAVMCNAQILSNVVANQKIHEAYGGVVPELASRAHQQHIVPVVDQALKKAKIDKSQLSAIAFTRGPGLMGSLLVGTSFAKSLAYGLGIPLIDVNHMQAHILAHFIEEKDFNKPPFPFLALTISGGHTQIVKVNDHFDMEVIGETIDDAVGEAFDKSGKLLGLGYPAGPEIDKRAKLGNPKAFKFTKPKVDGLNFSFSGLKTAILYFVQKQVKANPNFIEERLNDICASIQYTIIGILMDKLKLASKQTGITHIAIGGGVSANSGIREALKQSEAKFGWTTYIPKFEYTTDNAAMIAIVGHLKYLKGEYAQQNVMASARLKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFT1</accession>
    <name>A0A5C6ZFT1_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Succinate--CoA ligase [ADP-forming] subunit alpha</fullName>
            <ecNumber evidence="2">6.2.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Succinyl-CoA synthetase subunit alpha</fullName>
            <shortName evidence="2">SCS-alpha</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 7" type="primary">sucD</name>
        <name evidence="7" type="ORF">ESY86_10415</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 5">Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 5">
            <text>ATP + CoA + succinate = ADP + phosphate + succinyl-CoA</text>
            <dbReference type="Rhea" id="RHEA:17661"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.2.1.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Carbohydrate metabolism; tricarboxylic acid cycle; succinate from succinyl-CoA (ligase route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 5">Heterotetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the succinate/malate CoA ligase alpha subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.5" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00999"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004775">
        <property type="term" value="F:succinate-CoA ligase (ADP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01988">
        <property type="entry name" value="Succ_CoA_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017440">
        <property type="entry name" value="Cit_synth/succinyl-CoA_lig_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033847">
        <property type="entry name" value="Citrt_syn/SCS-alpha_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005810">
        <property type="entry name" value="CoA_lig_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005811">
        <property type="entry name" value="CoA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02629">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00549">
        <property type="entry name" value="Ligase_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001553">
        <property type="entry name" value="SucCS_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="SSF52210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01019">
        <property type="entry name" value="sucCoAalpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01216">
        <property type="entry name" value="SUCCINYL_COA_LIG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00399">
        <property type="entry name" value="SUCCINYL_COA_LIG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="1 2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="CoA_binding" evidence="6">
        <location>
            <begin position="4"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Coenzyme A binding" evidence="2">
        <location>
            <begin position="17"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Coenzyme A binding" evidence="2">
        <location>
            <begin position="96"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="2 3">
        <location>
            <position position="248"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared with subunit beta</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001553-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD88903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="292" mass="30015" checksum="668BC124B8FA1CCF" modified="2019-11-13" version="1">MSVLVNKDSKIIVQGFTGSEGTFHAGQMIDYGTNVVGGVTPGKGGQKHLDKPVFNTVAEAVKEVGADTTIIFVPPAFAADAIMEAADAGIKVIITITEGIPVADMIKAAEYIKHKACRLIGPNCPGVITPGEAKVGIMPGFVFKKGTVGIVSKSGTLTYEAADQVVKQGLGITTAIGIGGDPIIGTTTKEAVEMLINDEETECVVMIGEIGGQLESDAAKWYQNSGSKKPVIGFIAGVTAPAGRTMGHAGAIVGGSDDTAQAKKAILKECGIHVVESPAEIGKKVAEVLNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFW3</accession>
    <name>A0A5C6ZFW3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">ESY86_14410</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VKOR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012932">
        <property type="entry name" value="VKOR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038354">
        <property type="entry name" value="VKOR_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13462">
        <property type="entry name" value="Thioredoxin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07884">
        <property type="entry name" value="VKOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0874">Quinone</keyword>
    <keyword evidence="9" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="216"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="275"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="308"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="VKc" evidence="11">
        <location>
            <begin position="163"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin-like_fold" evidence="12">
        <location>
            <begin position="367"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006214"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF13462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TXD88077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="535" mass="61817" checksum="39B45C87ADC58398" modified="2019-11-13" version="1">MELLRPLFQYLDAENIALDNDEFEFQFNSHPDYPSLLAISDTLKFFNVHNGAFNVDSAQIELLPNTFIARLKDDKTEFLSFVEKKENVIWYTNGTEKKHNIPKSDFINIWDDLVLLAESDKYNISKPKPKNNYLNILLGLSAILFLVISIEYLPMKWYGLFYVFPIIGLFLSVTALKDLFKTRSKLLDKFCQVSSANDCKTVVNSSKWKLLETVGFSDLSVVFFSVQIVSLFVMGISGLSMDYFSIQIVLLALSVPIISLSIYYQKYIEKKWCPICLSISGLVLAELAYVVFLKSFNYLDFEITTQGALQFLLVGSVSTVFWYTLKNLLSRLNHLKENELKANRFKRNYTIFKKMLTAPSRLKLPDNELILGNPNANISISIVTSPFCGHCKDPQYMLKTLLEKYDDAINVSVLYNVNPKNQRLLQFARIITQLKLDKGDNAFNEAMDYWYETKDDEKWLGKYQDEENSGFETLLAKNQVWLSEHDINFTPCMFINGYRYPNEYGIADLLFFMDELIEDKSILIKENKIAEAEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFY7</accession>
    <name>A0A5C6ZFY7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_12420</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007492">
        <property type="entry name" value="LytTR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04397">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00850">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50930">
        <property type="entry name" value="HTH_LYTTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="5"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="HTH LytTR-type" evidence="3">
        <location>
            <begin position="139"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="243" mass="28514" checksum="7D740A7A166CD721" modified="2019-11-13" version="1">MIVLKAVIVEDSRLARNELKELIKTHPEIELLGEAKNVDEGYELINETKPDLLFLDINMPEKDGFELLEMLDEVPITIFTTAFDEYAIKSFEYNAFDYLLKPINQKRFSKSIEKVIENATSNHTQEPQKEDVLHLDKQIFIKDGEKCWLVKVQDISLFEIVGNYTRVFFKGNKPLIYKSLAQIEEKLPSDVFFRANRQQIINIHHVKKVVSWFNGKLKIEMHSGEEIEISRRQSYLFKEQLSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFY8</accession>
    <name>A0A5C6ZFY8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="10">C-type cytochrome</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ESY86_11295</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.280.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032858">
        <property type="entry name" value="CcoP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038414">
        <property type="entry name" value="CcoP_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13442">
        <property type="entry name" value="Cytochrome_CBB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14715">
        <property type="entry name" value="FixP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 5" id="KW-0349">Heme</keyword>
    <keyword evidence="3 5" id="KW-0408">Iron</keyword>
    <keyword evidence="4 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="129"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c" evidence="9">
        <location>
            <begin position="194"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="293"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="150"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD88816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="317" mass="35634" checksum="4F0F3E4423C211C9" modified="2019-11-13" version="1">MKNSIPAWLRIPIVFLIIVVLVELTIDSGNKLAIIERPEVSLFLIFVLLLLIGIEAIVRSLENILYQTLDAEAKERYNLKRSSQSKVLIWVKETYAKLRGGKEMEEEHEIILDHNYDGIRELDNDLPPWWLYGFYASIVFAFVYMARYHIFDGENQYDELQANLEQAKVEIEEYKKGAKDLVDFSTVTVLVDASDLKAGKTIYEMNCVACHKADGGGGIGPNLTDKHWILGGGIKNVFKTISEGGRAGKGMIAWKQSLKPAEMAQVSSYVLQFQGTTPTDGKEQEGDIWVDENAPKEAIPSSAMEVKSNDVLEIEKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG84</accession>
    <name>A0A5C6ZG84_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Efflux RND transporter periplasmic adaptor subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_13355</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="417" mass="46614" checksum="3B0C8C6DA9A02BD2" modified="2019-11-13" version="1">MDILLEKKRFSTKNLLLIGGIFLLLALIVFVILSSMGGSKLNVEKERISINAAEQGVFQENIPVNGIVLPITTIYLDALEGGRVEEKLAEDGAVLKKGDPILRLSNTDLELSLINQETQVYNLLTQMQISQNVALQNTINKLNQYTDVESGLIEAKRVYDLNSRLYEKGAIGRQDLIKAQNEYDYQKERMQLSKQILSQDSIAVKQEKGQVQSSYARTQNALELMRRKVADLVVKAPVDGQLTSLDAEIGQSKNKGERLGQIDVLSGFKVRADIDEHYISRIYTGQTGSFSFDGKSFELSINKVYTQVTNGRFQVDMQFSENVPEGIRRGQTLQIRLALSDEKQALLIPKGGFFQQTGGNWIFKVSEDGNTAYKVDITLGSQNTEYYEVLSGLQPGDKVITSSYDNYGDVEELILKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGA6</accession>
    <name>A0A5C6ZGA6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_13800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0675">Receptor</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="905" mass="104649" checksum="9FC16C214D1DDBE5" modified="2019-11-13" version="1">MLRHMKEKDLNLNMNGNNRKEIHVFSLVVFFTVQNLCFAQINISGHISDHNDHLYSVNIILKDSISKSIVAYTYSDDNGNYQLKADRYGQFNLVFTSLGHETKIIPVMLKPKQSKIEIDVVLIERTTNLKEVIINANVPMSIKKDTITFKTKFYRQGSEQTIEDLLKKIPGVQIDSEGTIKIGNQEIEKLMVDGDDLFEKGYKILSKNMPAYPIEAVEILKNYSNNRFLKGVEESNKVALNLKLDEKSKRIWFGNLQLGVGNDSFYELKGNLMNFGKKNKYYFLTNLNSTGYDATGDIESLIRPYRSNAPASLGDDQTLSSLLNLSPNQLNFKESRTNFNNAELLSLNAIFNPTEKLKIKTLGFFNWDENDFFRNSIDNVKVSGANFTNTEDFKLRNKKRIAFGKLDLTYNISKTKMLEATTKFNRGNFDDNSNLIFNGSSTLENLEHQNKLFDQKISYTNKFKAKKAFLITGRFIDESAPQQYELNQFFYQELFPENLDANKVAQVSNIQMQFAGINAHLLDRKENGNLLELQVGNTYRKDRLLTRFSLLEDGTVLNQPERYQNQTNYQVNDLYFKSKYRLEVKNIGLTAKLDLHQFFNQLQNNESTASQNPFFINPSIGLDWTINNKNKIISSYAYNTTNAKILDVYSDFVLTGFRSFSKGTGGFNQLDASSLIFNYQLGNWSDRFFANTFLIYSKNHDFFSTNTQIAQNYIQSEKILIKDREFISINSKLDYYFKFLSSNLKLDLGYTQSDFKNLVNNSGLREITSNNYKYGLELRSGFKGLFNYHVGTKWTTTKIQTTIHNKFTDNISFLDLSFVFNKRLDIKLQTERYYFGNLQTDKSYYFLDFDARCKLIENKVTIGLSGKNLFNTARFKTFSISDIGSSTTEYRLLPRFVLLKLEYRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGB1</accession>
    <name>A0A5C6ZGB1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ligase-associated DNA damage response DEXH box helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_15980</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000021">
        <property type="protein sequence ID" value="TXD87682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013701">
        <property type="entry name" value="DEAD/DEAH_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026362">
        <property type="entry name" value="DEXH_lig_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017170">
        <property type="entry name" value="Lhr-like_ATP-dep_RNA_helic_prd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045628">
        <property type="entry name" value="Lhr_WH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08494">
        <property type="entry name" value="DEAD_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19306">
        <property type="entry name" value="Lhr_WH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037307">
        <property type="entry name" value="Lhr-like_helic_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04121">
        <property type="entry name" value="DEXH_lig_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="1">
        <location>
            <begin position="16"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="2">
        <location>
            <begin position="231"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="803" mass="90981" checksum="DD07DA3D5EA813BF" modified="2019-11-13" version="1">MATKGNLPFPFQEQTWAKYAKGCSGMVVAPTGFGKTFSVFLAVVIDYLNHPEQYQKGLKLLWVSPLRSLAKDLAKAMTAAIEEIGLDWEVAVRNGDTPTKIRRQQERLMPDVLISTPETLHLLFSQKNNSRWFKSLNCVAVDEWHELLGNKRGILTELAVARLNQLSKNLSIWGITATIGNLEEAAKVLIPYPEKKTLMIKSKLKKKIKVIPVLPDEVEVLPWAGHLGRSMASKIIPIIHANKTTLIFTNTRGQSELWYQILLEADPDLAGLLAIHHGSIDKKLRNWIEDSISEGILKAVVCTSSLDLGVDFKPVDCVIQIGSAKGIARFMQRAGRSGHSPYEVSKIYMIPTHSLEIIEAAALKEAVKEQKVEARQPMVLTFDVMVQFMVTLAVGEGFKAEETYNLLKRTHAFSLMTEDEFAWAIQFITQGGNTLKSYEEFHKVFLDDDGLYKVKSRRISMLHRMNIGAIVSDAMLRVKFMSGGYIGMVEEYFISKLKPNDSFILAGRVLELLHIKDMTVFVKMSKAKKAISPSWMGGRLPLSSYMSHFLRKKLSDALNPGTQERELRFLHPLIARQSEFSHIPREDEFLVELIDTKEGFHLFMYPFEGRLVHEVISALIAYRLSKIEPLTFTIAMNDYGFELLSDQEIPLNENNVRTILSKEHLMEDVVASINAAEMASRKFRDIAVISGLVVQSMPGANRNNKSLQSSSGLIFRVLEDNEPNNLLLRQAYTEVFDQQLEEVRLKDAFDRIHNSKLIIKKTNTFTPLSFPIKVDSLRQSLSSEKLDKRIQRIQKETFRKAKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGC0</accession>
    <name>A0A5C6ZGC0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Excinuclease ABC subunit UvrA</fullName>
            <ecNumber evidence="15">3.1.25.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">uvrA</name>
        <name evidence="15" type="ORF">ESY86_10210</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.25.-" evidence="15"/>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009380">
        <property type="term" value="C:excinuclease repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004602">
        <property type="entry name" value="UvrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041552">
        <property type="entry name" value="UvrA_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041102">
        <property type="entry name" value="UvrA_inter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17755">
        <property type="entry name" value="UvrA_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17760">
        <property type="entry name" value="UvrA_inter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00630">
        <property type="entry name" value="uvra"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0228">DNA excision</keyword>
    <keyword evidence="12" id="KW-0234">DNA repair</keyword>
    <keyword evidence="11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ABC transporter" evidence="14">
        <location>
            <begin position="608"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="643"/>
            <end position="650"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TXD89132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="953" mass="106996" checksum="3FC7382F18BCFD49" modified="2019-11-13" version="1">MSKFDDAIEVRGARVHNLKNIDVSIPREKLVVITGLSGSGKSSLAFDTIYAEGQRRYIETFSAYARQFLGGLERPDVDKIDGLSPVIAIEQKTTSKSPRSTVGTITEIYDFLRLLYARASDAYSYNTGEKMVSYNDEQIKDLIKESYQGKRINVLSPVVRSRKGHYRELFEQIAKQGFVKVRTDGEVKDIVKGMKLDRYKIHDIEIVIDRLKIDDTENNDKRLAESINTAMYHGDDVLMVLDQDSNEARYFSRNLMCPSSGVSYPNPEPNNFSFNSPKGACPNCNGIGTLYKVNEHKIVPDDSISIKAGALAPHGPQKNSWVFKQFETIAQRFDFKLSDAYKDIPKEAKQMILFGGKDKFSVESKTLGVTREYKIDFEGVANFIESQYENADTTSLKRWAKDYMDKVKCPDCEGARLRKESLYFKVNGLNIAELAQKDIVDLSAWFKDLHKHLSDKQFKIAEEVIKEIKSRIQFLLDVGLDYLSLNRGSKSLSGGEAQRIRLATQIGSQLVGVLYILDEPSIGLHQRDNEKLINSLTALRDIGNSVIVVEHDKDMIERADYVIDIGPKAGKYGGEIISTGTPKELLEHNTLTADYLNGKRKIPVPKKRREGNGKKIVLKGCTGNNLKNVSIEIPLGKMIGVTGVSGSGKSTLINETLYPIMNAHYFNGVKIPMPYKSIKGLEHIDKVIDINQSPIGRTPRSNPATYTKTFDEIRSLFAKIPEALIRGYKPGRFSFNVKGGRCETCQGAGVRVIEMNFLPDVYVECETCQGKRFNRETLEIRYKGKSISDVLDMTMNEAVAFFEHIPKIHQKLSTIVDVGLGYITLGQQSTTLSGGEAQRIKLATELSKRDTGNTFYILDEPTTGLHFEDIRVLMLVLNKLADKGNTVLIIEHNLDVIKMCDYLIDIGYEGGQGGGKVVAKGTPEELIKDKKSYTAQYLKKELKSRKLEIEDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGC8</accession>
    <name>A0A5C6ZGC8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">rplD</name>
        <name evidence="7" type="ORF">ESY86_14835</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Forms part of the polypeptide exit tunnel.</text>
    </comment>
    <comment type="function">
        <text evidence="5">One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01328_B">
        <property type="entry name" value="Ribosomal_L4_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002136">
        <property type="entry name" value="Ribosomal_L4/L1e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023574">
        <property type="entry name" value="Ribosomal_L4_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013005">
        <property type="entry name" value="Ribosomal_uL4/L1e"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10746">
        <property type="entry name" value="PTHR10746"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00573">
        <property type="entry name" value="Ribosomal_L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52166">
        <property type="entry name" value="SSF52166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03953">
        <property type="entry name" value="rplD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="46"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="47"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD87942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="209" mass="23032" checksum="55CC6875D4A544EA" modified="2019-11-13" version="1">MKIAVLDINGKDTGRQAELSKDVFAIEPNNHAVYLDVKQYLANQRQGTHKAKERAEISGSTRKIKKQKGTGTARAGSIKSGVFKGGGRMFGPRPRNYSFKLNKNLKRLARKSALSMKANDKAIVVIEDLNFDAPKTKNFTAILKALDIQDKKSLFVLGASNNNVYLSARNFKGSEVIMNSELSTYKILNANKIILLEGSLEGIESNLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-02-10" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGH3</accession>
    <name>A0A5C6ZGH3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glyceraldehyde-3-phosphate dehydrogenase</fullName>
            <ecNumber evidence="4">1.2.1.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_11040</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.12" evidence="4"/>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004365">
        <property type="term" value="F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020831">
        <property type="entry name" value="GlycerAld/Erythrose_P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020830">
        <property type="entry name" value="GlycerAld_3-P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020829">
        <property type="entry name" value="GlycerAld_3-P_DH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020828">
        <property type="entry name" value="GlycerAld_3-P_DH_NAD(P)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02800">
        <property type="entry name" value="Gp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00044">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00078">
        <property type="entry name" value="G3PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00846">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00071">
        <property type="entry name" value="GAPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gp_dh_N" evidence="3">
        <location>
            <begin position="130"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="482" mass="53336" checksum="9052443855ADF258" modified="2019-11-13" version="1">MPLQGTYEQELAFQADRRRATVEFIKIISDLWYDKSIELVLFRNQLIDRNVSEILNLHEYAGAFVKKPISIFDSVEIAQAIKDLNLPPAKLDIGKLTYEFHLDDQKYSNATGFVAEKLKNAKKNKVNPPKDVVLYGFGRIGRLVARELMTKTGKGSQMRLRAIVTRGKIDATVLEKRASLLRNDSVHGNFSGTVNIDVKNSALIINGTTVNVISANHPEDIDYTAFGIKNALVIDNTGAFRDKDALGRHLKSKGVSKVLLTAPGKGIPNIVHGVNHLEYDPDKVNIFSAASCTTNAITPILKAVQDAFGVVSGHLETIHAYTNDQNLVDNFHSKYRRGRAAGLNMVITETGAGQAVTKALPSFEGKLTSNAIRVPVPNGSLAILNLDLETEVSVEDINTVMKNNALEGCLVEQIKYEMSDELVSSDIVGSSAPSIYDSKATIVRKDGKNAILYIWYDNEYGYSHQVIRLAKYISKVRRFTYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGX6</accession>
    <name>A0A5C6ZGX6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MBL fold metallo-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="42"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="286" mass="32911" checksum="5EB15638FB0C633A" modified="2019-11-13" version="1">MQLYPINAGNFKLDGGAMFGVVPKSLWNKTNPADANNMIDIAARCLLIEDGDRLILIDTGMGNKQSDKFFGYYYLWGNDSIDNSLKAHGFHRDDITDVFMTHLHFDHCGGGIQWNKDRTGYEPAFKNARFWSNQDHWDWATHPNNREKASFLEENILPIEQSGQLQYTALPENDFLKDSKLGFDIFFANGHTDKQMIPMIEYKDKTICFMADLLPTVGHLPLPFVMGYDTRPLLTLDEKQKFLNLAADQNYYLFLEHDAHNEIITVEHTEKGVRLKETYTTNAIFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH64</accession>
    <name>A0A5C6ZH64_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase family 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_09785</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="8"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="319" mass="36924" checksum="032222FD58C5CA67" modified="2019-11-13" version="1">MEYSPKVSIVVPVKNGMDTLPKLMEGIQNQTCFEDCEVVVIDSGSTDNSIDFLSQFNFVKLISIDPTTFNHGATRNLGVSHANGEFVVMTVQDALPTDELWLEKMLSHFKDETIAAVCGQQAVPHHANKNPHEWFRPQSEAKAKKIHFKSKQEFLNLSPKEQRAACGWDDVNAMYRKQALLDLPFQPLVFGEDMLWAKMALEKGNALVYDASARVYHYHFQFPEYTYKRTLIAKFFIFKCFNYLDTRTYSFKSYALVVFRNFKWKCAPKWILHNFNIIRNHRKATHFLINAINNNTVEVLEKELAIKIPIGQQHTKKHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH96</accession>
    <name>A0A5C6ZH96_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Gamma-glutamyl phosphate reductase</fullName>
            <shortName evidence="7">GPR</shortName>
            <ecNumber evidence="7">1.2.1.41</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Glutamate-5-semialdehyde dehydrogenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Glutamyl-gamma-semialdehyde dehydrogenase</fullName>
            <shortName evidence="7">GSA dehydrogenase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">proA</name>
        <name evidence="9" type="ORF">ESY86_09955</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>L-glutamate 5-semialdehyde + NADP(+) + phosphate = H(+) + L-glutamyl 5-phosphate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:19541"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58066"/>
            <dbReference type="ChEBI" id="CHEBI:58274"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.2.1.41"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the gamma-glutamyl phosphate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.41" evidence="7"/>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004350">
        <property type="term" value="F:glutamate-5-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07079">
        <property type="entry name" value="ALDH_F18-19_ProA-GPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00412">
        <property type="entry name" value="ProA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012134">
        <property type="entry name" value="Glu-5-SA_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000965">
        <property type="entry name" value="GPR_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000151">
        <property type="entry name" value="GPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00407">
        <property type="entry name" value="proA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0521">NADP</keyword>
    <keyword evidence="6 7 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 7" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="8">
        <location>
            <begin position="54"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="Aldedh" evidence="8">
        <location>
            <begin position="288"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD89086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="399" mass="44602" checksum="70C95958FDC5B5C0" modified="2019-11-13" version="1">MKLLDTNIKNTVLDSMVAILDKNRESILKANQKDLDAFDRDDQALYDRLVVNDAKIEGMITAIKEVRSQEDPVGKEISDLTLDSGLKITNRTAPFGTIMIIYESRPDVTIEAAVLAFKANNKILLKGGKEALQSNLVLEKCWHQALEENGLSKDWIRLLHLKREETQEFLKNPTEKIDLIVPRGGERLIKFVKDNATCAVLISGRGNNFLYVAKDANWEKTLKVIINAKTEKISGCNALDKVLIDKHIPNYTEKVKELQSVLSHLKVELVVDDAIGNILPKENKITSEAIWYEEFLAMKLLIAEVDGVDQSIEMINTYSGGHSAVIMTENKDLAQKFMEQVDSAAVYHNASTRFTDGGQMGVGAELAISTDKLHHRGPLGLKQLVTNKYYVFGDGHVRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHD7</accession>
    <name>A0A5C6ZHD7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase family 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10165</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="6"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="313" mass="35892" checksum="7E2088B28AABDCFC" modified="2019-11-13" version="1">MSPLFSIVIPLYNKANEISQTLESVFKQTLKEFEIIIVNDGSTDNSLLEVQKFEDKRISIFTTENKGVSHARNFGIEKAKAPLIAFLDADDLWYPHHLENLKQLYQTYPNCGMYCKAYEKSYLGRHIVAAKFNGLESDFEGIVPDYFENSLIDAIAWTSATAIPKIVFKTYGVFDTNLKSGQDTDLWMRVALNEPIAFSKNISAIHVLTGQEHHLSQSKHRVDRLKLLNKFKEAEKSSKSLKKYMDYNRFSMAIERKCQGDSSTFKQLKAEINLDNLNAKQRLLLKLPKPLLNLLKKSQQQLIGYGLYFSAFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHE5</accession>
    <name>A0A5C6ZHE5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-lactamase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_11595</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023015244" evidence="1">
        <location>
            <begin position="20"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase" evidence="2">
        <location>
            <begin position="58"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="491" mass="54813" checksum="1D55C93301D1DA84" modified="2019-11-13" version="1">MKFKKLLLSLIFISNIGIASYSQTSNIQKFDTIQQRINKVENSLSPLALNPGASLWNLEKQMQKYNVSGLSIAVIHNYEIEWAKGYGSTGAKEIPNVTEQTVFQAASISKFVNAVAMLKLMELKKIDLNEDINNYLTSWKFPYNKNVDTNPITIRQLLSHTAGLSTHGFGGYKNSDKLPSIIQTLEGKNPANSDKVEQILPTNKKFKYSGGGTTISQLILMDNSISSYESFLNKNLFEPLQMNNSFYSTEFDKYPKDLAFGHKGNGKTLNNNYNLYPESAAAGLWTTPTNLSKLITDIQRSLKNGTGKILSQQATKELIEPTLKNSNSALGVFSENQNGQLYLQHSGANKGFRGKFYFSAENGNGVVIMLTGTNTEIIEEIIRSVVLVYNWAGFEKLLVSPELNLRDIDLRKYIGTYVLENRNVQVSLKKGDLILTEKGKWSSKLTALNNSTFVVDIVKPQATIEFVTDTDGSISKCILKQGELTEWIKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHM6</accession>
    <name>A0A5C6ZHM6_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">5-formyltetrahydrofolate cyclo-ligase</fullName>
            <ecNumber evidence="3">6.3.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_13820</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>(6S)-5-formyl-5,6,7,8-tetrahydrofolate + ATP = 5,10-methenyltetrahydrofolate + ADP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10488"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57455"/>
            <dbReference type="ChEBI" id="CHEBI:57457"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the 5-formyltetrahydrofolate cyclo-ligase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.3.2" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030272">
        <property type="term" value="F:5-formyltetrahydrofolate cyclo-ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002698">
        <property type="entry name" value="FTHF_cligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024185">
        <property type="entry name" value="FTHF_cligase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23407:SF1">
        <property type="entry name" value="PTHR23407:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01812">
        <property type="entry name" value="5-FTHF_cyc-lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006806">
        <property type="entry name" value="FTHF_cligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02727">
        <property type="entry name" value="MTHFS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="3"/>
            <end position="7"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="132"/>
            <end position="140"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006806-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="187" mass="21837" checksum="4566E5601A28582D" modified="2019-11-13" version="1">MTKLELRKTYKVLRKSLSPEDVEELSLKIANQLLRLEVWSHDFYHIFLSIVEFNEINTDYILNILSGKDKHIVLSKSDFETQEMQHFLLTDGTRIKKNKHNIPEPIDGIAIDTSKIDVVFVPLLAFDNSGHRIGYGKGFYDRFLSQCRPETIKIGLSFFRAEAQIEEVFDTDIKLDYCVTPEEVYRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHN4</accession>
    <name>A0A5C6ZHN4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">M1 family metallopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_12970</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="2">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034015">
        <property type="entry name" value="M1_LTA4H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45726">
        <property type="entry name" value="PTHR45726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023042318" evidence="3">
        <location>
            <begin position="23"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M1" evidence="4">
        <location>
            <begin position="367"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="375"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="457"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="374"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="378"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="397"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR634015-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR634015-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD88424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="625" mass="70829" checksum="B0F27D6B779146BE" modified="2019-11-13" version="1">MKLFSISILGVLCTLFSSELMAQSPKMEYKTNGYWQQQADYSMEIDMNVNTYQYKGKQQIEYTNNSPDVLDRVYYHLFFNAFQPDSEMDARLNSIPDPDGRMVNNLGTKENPNYESRISILKPNEIGYIKVNSLQQNGRPVKFTIDGTIMIVDLNTPIASGASVDFDMVFDGQVPLQVRRAGRNSDEGVALSMSQWYPKMAEYDDEGWHADPYIGREFYGVWGNFDVKITIDKDYMIGGTGYLQNPDEIGFGYSENSVKKQKSKNLTWHFVAPNVHDFTWAADPDFVHDTMQVPDGPLLHFLYKKSLDKPFLDSWKKLQPKTVALMQYFSEHIGEYPYEQYSVIQGGDGGMEYAMCTLITGERSFGSLVGVTAHELAHTWFQFLLATNESKHEWMDEGFTTYISSLAMNEIMDPKKDNPLASAYSGYSYLATSGYEQPLTTHADRYNVNQAYGISAYSKGAVFIAQLAYVIGDDNLRKTIKKYYNDFAFKHPKPADFIRTAEHVSKLELDWYLTDFGQTTNIIDYGVKSVDGKTITLERLGNMPMPIDLEVSYTDGSTQSYYIPLRMMRGGKPTLATTIDNWAWAYPTYSFAAASTVKSVQINPTGMMADVNDTNNVFPNTAEGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHP6</accession>
    <name>A0A5C6ZHP6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_09560</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="69"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="155" mass="17427" checksum="8ADE9319D32D00C8" modified="2019-11-13" version="1">MKNKTKTYLLLVAVLGVWGSIGYKIWSGMSPDVAEITPTEFDGAFNPQPMTTLDTFSIQDLERDPFLGTLSSSKRQVPKPNANQQPKTPENIPTIAYNGILRKQSTSDQVFVVSINNQQFLLKKGQVADSVKLLKGNEDEITMRYHNKNLNIKRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI21</accession>
    <name>A0A5C6ZI21_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">HAD-IC family P-type ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_11320</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021993">
        <property type="entry name" value="ATPase-cat-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12156">
        <property type="entry name" value="ATPase-cat_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="SSF55008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="167"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="202"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="233"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="257"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="420"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="443"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="734"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="760"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="5">
        <location>
            <begin position="85"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD88821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="812" mass="90588" checksum="595856678FBB8BC1" modified="2019-11-13" version="1">MEQNHCFHCGDDCNSSVIRYDDKAFCCNGCKTVYEIFSENDLTCYYDLQASPGAVPKEIEGKYDFLSQANIIEKLTEFNDGKTQVANLYIPHIHCSSCIWILENLNKLNPNITTSQVNFGKKSVRVTYNAEKGSLKETVLLLSSIGYEPYISLDDFKTGQQKVNRSLIYKVGIAGFAFGNVMFLSFPEYFEVGEFWLEQYKVFFRWLMFAFSLPVVFYAGADYFTSAYKGLRANLLNIDVPIALGIAVLFLRSTVEIIFDLGSGFFDSLTGLVFFLLLGRFFQQKTYNFLSFERDYKSYFPIAVTIISSEGIETPIQVYDIKKGDRLLIRNEELIPVDGILINGRAKIDYSFVTGESETLSKVSGDKLFAGGKQTSGVLEMEAIKSVEQSYLTQLWSNDVFSKNKEDGFTTLTNKISKRFTFAVLSIAVIATTYWLFVDASKAMNVFTAVLIIACPCAIALAAPFTFGNLLRIFGKLKFYVKNASVIEQLAAIDTIIFDKTGTITSNKHSSATYDGVTLNASEEILLKNTLRGSNHPLSRTLYDILDENNIITLNHFEEHLGKGIEATHNLDRIKIGSASFVGAANSSILNTQVHISTNDSYKGKYTFYNSYRKGLAKLFNQLKKQYDLVILSGDNEGELENLKKLLPSKTKLIFNQKPDDKLEYIKFHQTEGAKVLMVGDGLNDAGALAQSDVGIALSENVNVFSPACDAILDASKFNQLHQFIKASKSAIRIVKWSFILSLFYNSIGLYFAVTGQLAPVIAAILMPLSSISIVVFTTIATNNIGALRTPKKNAAKFQHQKRPNALRQAKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI80</accession>
    <name>A0A5C6ZI80_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD-binding oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="1">
        <location>
            <begin position="30"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="401" mass="44995" checksum="73624C9C3EF53BE5" modified="2019-11-13" version="1">MKLRSSEPFWLEKNGILHSYPSLRKNVKADILIVGGGITGSLIAHQCIKDGYKTVLIDKREIAHGSTSVTTSMLQYEIDVPLFELIEKIGTEAAVANYRGCSEAIDTLGKISKQVKSGCGFEKKDSLYFAAFKKDVPKLKKEFEARKTHGFPVVWLEAEEITKRFGLQNTHGGILSKQGGSIDAFRLAHDILAYNHKKGLDIFDKTVIEKVSYKKNGVTTITKNGCSITSKKILYCNGFESTSIIKEKFVKLLSTFAMVGEQLEDNQDQLAGTLFWNTADPYMYMRTTDDGRLLIGGEDEDYVNPEKRNKNIGKKAEKLQNYLKKILPDYDFVNDFAWAGTFGETEDGLPYIGKHKDFESTYFVLGFGGNGITFSVIGMDIISQLLKGKKHPLTKYYQFGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI85</accession>
    <name>A0A5C6ZI85_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">SRPBCC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_06570</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="151" mass="17727" checksum="D2B7A42A7939ECD7" modified="2019-11-13" version="1">MIYNTEIKICLPIEQVIKKIDNVENLKHWQRGLVSAEHIIGAPGALGSKMKFNYRFGNRSMQVVETITKRNLPNEFHASYDTKGIHSIQENYFEKTPEGFTKWVIKCEFLPLNFFMRVMILVSPNMFRKQSEKYMKDFKNFVENEISVANV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIA6</accession>
    <name>A0A5C6ZIA6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029050">
        <property type="entry name" value="Immunoprotect_excell_Ig-like"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="155" mass="17731" checksum="527060CD693779D8" modified="2019-11-13" version="1">MVPIKEAITSGSWLQCEKRNNLFEANQFRIKVNSFRKLNLSEIDEPEEINDLENSAVLWLMNIEVVNLNKEPTKTHNNVYGLKLVDNDDFIFPVFLDGHLNCFSDFAKTSGLKRFYAGTILPKIKTLGSLVFQLPDDDDAEYFISLEDNGIVQEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIB4</accession>
    <name>A0A5C6ZIB4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Acyl-CoA dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_10675</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="8">
        <location>
            <begin position="14"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="129"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="236"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD88950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="397" mass="44187" checksum="EC509DF5A937C373" modified="2019-11-13" version="1">MLQSVLLPRDIYATEEHQMMQEMIRDFIKNEIMDQIDAWEEKGMVSRAIWERAGALGLLCIDMPEQYGGSGLDFSFSALFIEELGREGITGPGFSLHSDIVAPYLLKYGTEAQKQNYLPRMASGKLITSIGMTEPNCGSDLKAITTNAVDKGDHYLVNGQKTFITNGYLCDMSVVAVKTNVGTAKEGVSLLIMESAYDGFEKGVPFKKIGMKSQDTCELFFDNVKVPKENLLGEEGMGFKIMMTELARERLTVGLNAIAGAEGAIEKTIAYTSSRTAFKQPIAGFQNTQFKLAECATQLQIHQAFLDRCTLLVSKDELTAESASMAKYSATEMHGRVVDECLQLFGGYGYMWDYPIARMYADNRVARIYAGTNEIMKILIARGLFKELFQEMKTKKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIC0</accession>
    <name>A0A5C6ZIC0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sodium:proton antiporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_12950</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015299">
        <property type="term" value="F:solute:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02254">
        <property type="entry name" value="TrkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="79"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="171"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="240"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="296"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="324"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="354"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="387"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="domain" description="Na_H_Exchanger" evidence="5">
        <location>
            <begin position="9"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="domain" description="RCK N-terminal" evidence="6">
        <location>
            <begin position="424"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD88421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="630" mass="69056" checksum="7293AE6B97475274" modified="2019-11-13" version="1">MIELAGIIILGILAQWVAWKLKIPAILPLILIGLLVGPISAEFLSDDGTKWIEPIWNEPIMNESGVLSPGKGLFPGESLFYFVSLAIGIILFEGGLTLKLGEIKNVGPVITKLITIGSVVTFFGAAVAAYFIFELSWEISFLFSGLIIVTGPTVITPILRNIPLKKDVSAVLKWEGILIDPIGALVAVLVYEFISVDAGSEFTKTALVEFGKIVLFGSAFGFGFAHALNFILNKKLVPHYLMNVFSLAAVLGVFVLSDVFAHESGLLAVVVMGMVLGNSGSPYLKDILYFKESLSVLLISILFILLAANINYEELLLIYNWKTAILFAVIVFVIRPLGVFLSTHGSKLQLNEKLFISWVGPRGIVAAGIASLFGLKLAKIGVVDAEYITPLVFVIVLGTVLLNATTARLFAKIVGVFLDKSNGILIVGASKVSRLLGHYLEINGRHVVLIDSNQTNIAKARDLGLEALNTNIYSDNLDDNIELNDVGYIMAMTANSDINKYAISRFGKQFGENGSFRLVTSDEMNDSNNYPKEGLFSRTDDYIRLSEVTRKYPSIQEIDLRDAAHYSSLVEITENDKDIIPLFLKDADGELHIISSFHKKDEAIETGWKLVYIGKPFDVEELKNEEVPEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIM4</accession>
    <name>A0A5C6ZIM4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Alginate_exp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11225</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025388">
        <property type="entry name" value="Alginate_export_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13372">
        <property type="entry name" value="Alginate_exp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Alginate_exp" evidence="1">
        <location>
            <begin position="23"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="421" mass="47641" checksum="D2C8ADCCF02FD529" modified="2019-11-13" version="1">MKYLAIILCLGFGMENFAQNFEISAQLRPRLEYRHGFKTLFQDSEDAAVFVSQRSRLNLGYTTEKLNLYLSLQNVRIWGEVATMATADVNGTAVHEAWAEVNLNSQIAFKFGRQELVYDDERLFGNVDWAQQARSHDALLFRFKPSAKHQLDLGLAINAERESIFEQEYLVNEYKSMQYLWYHTNLKNIKLSLIALNTGYAFEDDAAEQEIDYFQTFGTHLNYGKNRMKTDASLYYQTGQLANADLSAYNASLNATYSISKVFSAGLGAEYISGTDMDATNGKLESFNPLFGTNHKFNGLMDYFYVGNHINSVGLIDLNAKLIYHNAKFSAQLVPHLFSSAATIVNSTNQKVDDNLGTEIDLTLDYHLTKDLSFHAGYSHLFATESMETLKGGNSDATNNWAWFMINVNPSLFKTSFSKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIQ3</accession>
    <name>A0A5C6ZIQ3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_04680</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="184" mass="21032" checksum="E31AA4FE19DD471B" modified="2019-11-13" version="1">MQKLTFLIFGLIILTSCSSEKERDPFEVGKTYVGSLTDSTQVKDLELIFPNDSIVTFTNINGINRQNAEIDIYDSSGKKLLELTPKTRQDSTAMIKSVQFFDQRFKTTKNISTLSTFKDIQEQYKISSINNLIRTVVISVNEINASFTIDKSELPANLRFDMDLKIDAVQIPDNAKIKYFMVHW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIV6</accession>
    <name>A0A5C6ZIV6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">2TM domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_12230</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025698">
        <property type="entry name" value="2TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13239">
        <property type="entry name" value="2TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="2TM" evidence="2">
        <location>
            <begin position="26"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="118" mass="13898" checksum="5B16D054FEC0A4B8" modified="2019-11-13" version="1">MDKDRRNHLSALTTSDSNLDRDLYELASKRVERLKGFYIHLSVYVVVNLLIVVSNINDLEPGESYFKWQNFITLGFWGIGILAHSASVFIPNLLFNSNWEARKMQEFMDKEVEQQRWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIW0</accession>
    <name>A0A5C6ZIW0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF2971 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_05405</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021352">
        <property type="entry name" value="DUF2971"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11185">
        <property type="entry name" value="DUF2971"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="260" mass="30433" checksum="E5DBBA9C24C4662D" modified="2019-11-13" version="1">MYSIFDQDHELSIKMGIPNVFRFRPPNVNTLSELKENYIWFSDRDSLNDELDSNPEFVKLSTNPEEQKLLYNTIAENILDPKTKAYFDKNMDADRLQEFASTKIKPFVSSFGIACFTMYPMNEKLWDIYSENNKGICLHFDSSDDSSFFHNILPIHYVSRIKEREYSAISQPNHIIDLFYKKTEKWSYEKELRLLKEETGKIKFKPSSLQNVLIGCDAEQDFINTVVGIVKDNYNKVNIFQVIEPVSIGKLSYKPLYIPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ24</accession>
    <name>A0A5C6ZJ24_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">YfhO family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11875</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018580">
        <property type="entry name" value="Uncharacterised_YfhO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38454">
        <property type="entry name" value="PTHR38454"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09586">
        <property type="entry name" value="YfhO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="170"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="192"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="344"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="370"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="410"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="442"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="502"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="527"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="785"/>
            <end position="805"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="816" mass="91535" checksum="FA447E063CA0FC62" modified="2019-11-13" version="1">MQFSFKKILPHLLVLIGFVVVSLIYFSPVLQGKQIEQSDIMHYIGMSKQQKEFKAETGEETYWTDSAFGGMPTYQLGAAYPHNYIKKLDTALRFLPRPADYLFIYFLGFYVLLLALKVDYRLSALGALAFGFSTYLIIILGVGHNSKAHAIAYMPLVLSGIILTFRKRYIFGFLLTTIALGLEIQANHFQMTYYLMLLVLVLGVAYLVDAYRKKMLPHFFKSVGIMSIGVILAVGLNATNIMATQEYVKESTRGKSDLTINADGSQKEITSGLSKDYITEYSYGLVETFNLFIPRFLGGGSGEDVGKDSASYEFYKTIGASPVQALEAVAETPTYWGDQTIVEAPAYIGAVVIFLFVFALFLVKGRLKWWLVGASILSLLLSYGKNFGFLTDFFIDYVPLYNKFRAVSSIQVIIELCLPVLAIFGLVKLFNDFDKDEDKLKALKYSTLIVGGLALVFLLFKSTFFDFVGARDGQFRQMYGEYGQAFVDALKEDRKSFFTQDTLRTLILVLLSAGSIFMFLKKKISENVVIGIFAILILFDLVGVNRRYVNNDNFVSALQVNKPYQANAADLEVLKDKTHFRVLDVSQASAMPARAAYFHNSLSGYHAAKLKRFDELYDFHIAKNNMEVLNMLNTKYIIVDDEANQIQATTTYTQPNGNAWFVSELEKLNSANAEIKALDSLNTKVKAVTTASDLSTQRFTVDSLASIKLSKYEPNLLEFETNNAHNGFAVFSEIYYGNGWQVTLDGKKVPHHRVNYVLRGMNVPAGTHKIVFKFEPEVIQTGSQIALGSSILLILLIFGGTYMAFRRTSETSKKLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ54</accession>
    <name>A0A5C6ZJ54_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_07020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="259" mass="30592" checksum="E2BAF974943BD0AD" modified="2019-11-13" version="1">MKYPYIALLLLLLFNCKNDKRQDNVQENEKTEQTKSLATDTVPVLERTDTDLDKSISIEIKQKKLIDKKDERDQFQNLILDKSYLKDQKDYTINFKYPLLNESLKPTHVNFNNFMNDYYVNVSKTISDIEQNKLLCDSITAKTFREERFIDYKIYGLNDQLVSVLFYKENFYSGAMHPSYSFDCFNFDLNSGVFMTYESFFAQGSEDELLNIINGKINKKMATGELYYDCWELSSSDFFESKNNFVLNDTYLEFYFAIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ55</accession>
    <name>A0A5C6ZJ55_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Undecaprenyl/decaprenyl-phosphate alpha-N-acetylglucosaminyl 1-phosphate transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_09895</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008963">
        <property type="term" value="F:phospho-N-acetylmuramoyl-pentapeptide-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000715">
        <property type="entry name" value="Glycosyl_transferase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018480">
        <property type="entry name" value="PNAcMuramoyl-5peptid_Trfase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22926">
        <property type="entry name" value="PTHR22926"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00953">
        <property type="entry name" value="Glycos_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01348">
        <property type="entry name" value="MRAY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="17"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="87"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="230"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="261"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="303"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="336"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD89077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="378" mass="41956" checksum="E493E33FC7971553" modified="2019-11-13" version="1">MIQEILNYFNPLEHLELWLILAFFLAFMVSMSTFPAIFNIAEAKHLMDEPGDRSIHSVKTPTLGGVGIFISLVVVITMLGGLLDTKILLLILGSLTILFFLGLKDDLLILSPTKKLFGQFLAAMLLIIFTDTRILGLSGLFGVTIMPYWVSVAFTLFVYLLVINAYNLIDGVDGLAGCLALLGSGAFAFIAIKIDDVTMSTVAVGTVGALIPFLRLNFSKHKKIFMGDTGSMIIGFLLAFFAVRFIGSTQSTPASEFSNSAPIMVLAILFFPLLDTFRIFMIRLVLLKKSPFSADNNHLHHRFLGLGFSHVQTTMYIVILNLMLVAFAYAMRDFDIHYQFMALALVGMLLYSVLFIYNWLMIKGGLPQLLNAVKNYKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ66</accession>
    <name>A0A5C6ZJ66_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glutamate 5-kinase</fullName>
            <ecNumber evidence="7">2.7.2.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Gamma-glutamyl kinase</fullName>
            <shortName evidence="7">GK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">proB</name>
        <name evidence="9" type="ORF">ESY86_09960</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + L-glutamate = ADP + L-glutamyl 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:14877"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58274"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the glutamate 5-kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.11" evidence="7"/>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00359"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004349">
        <property type="term" value="F:glutamate 5-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04242">
        <property type="entry name" value="AAK_G5K_ProB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00456">
        <property type="entry name" value="ProB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041739">
        <property type="entry name" value="G5K_ProB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001057">
        <property type="entry name" value="Glu/AcGlu_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011529">
        <property type="entry name" value="Glu_5kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005715">
        <property type="entry name" value="Glu_5kinase/COase_Synthase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000729">
        <property type="entry name" value="GK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00474">
        <property type="entry name" value="GLU5KINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01027">
        <property type="entry name" value="proB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 7" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AA_kinase" evidence="8">
        <location>
            <begin position="4"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="168"/>
            <end position="169"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD89087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="256" mass="28398" checksum="3CA383BC6432F767" modified="2019-11-13" version="1">METNRVVVKVGTNVLTNKDNRIMGPILKELVRQISVLYERDIMVILVSSGSAIAGKEVLGETSIKDPSTRRQVYSAVGQPRMMRHYYSIFHDYGMRCAQVLATKRDFDPGKHRENMINCYEGLLSEGIIPIANEDDATSLTMSMFSDNDELASLVAELLDADRLIILSDTDGLYTGHPDDVNSRKLNEVKVDQDVEQYVKASNKKEGEGRGGMASKLKIAKGTASKNIPTYIANGKRPNVIVDIIDNKDIGTKFIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJE5</accession>
    <name>A0A5C6ZJE5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Tryptophan-rich sensory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_06665</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TspO/BZRP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15904">
        <property type="entry name" value="TSPO_MBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038330">
        <property type="entry name" value="TspO/MBR-related_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004307">
        <property type="entry name" value="TspO_MBR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10057">
        <property type="entry name" value="PTHR10057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03073">
        <property type="entry name" value="TspO_MBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005859">
        <property type="entry name" value="PBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="46"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="76"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="130"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD89879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="153" mass="17499" checksum="7A745FA4538A0726" modified="2019-11-13" version="1">MKFWKAFIVFLILNFAALGLGAWLMGDGAQSQWYLALNKAPWTPPGWVFGAAWTSIMILFSIYMAFLINARTTKKVIILFFVQFLLNISWNLVFFNQQLIAIGLAVITALTLIVAAFFVTYLNDLKWKSLLILPYLIWLGIATSLNLYVFIYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJG8</accession>
    <name>A0A5C6ZJG8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Serine/threonine protein phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_09085</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="1">
        <location>
            <begin position="3"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="244" mass="28230" checksum="15E768CE045C37E1" modified="2019-11-13" version="1">MKRTLAIGDIHGGLKGLKQLLARIDSKEDDQLIFLGDYVDGWSESAQVIQYLMEFSKRQECIFIKGNHDVWCEDWLREEKAPAVWQQHGGKGTIASYKDFSKSEKKAHLKFFEAMPLFHIDDQDRLFIHAGFTSMHGVAHETYEENFYFDRTLWEMALVADRFVQKNAFNYPNRLKHYHEIFIGHTPTLNFNETEPMKALNVWNVDTGAAFTGPLSAIDIDSKTVIQSDTVQSLYPYEKGRNKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK38</accession>
    <name>A0A5C6ZK38_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_09720</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="97" mass="11310" checksum="85E059ACCE99E609" modified="2019-11-13" version="1">MKTEDEDEERSARICVICGKYLVAAVCLARRYRGSTRKKDEDEDEDEDEDDPDSYRENLNLKLKLNLNLKLNLNSGSNLEQKQSQNFKNQKSLIVNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKB8</accession>
    <name>A0A5C6ZKB8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyltransferase family 4 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_09825</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="420" mass="48294" checksum="3B95569A2DE7CF31" modified="2019-11-13" version="1">MKNVLIIYPHWHPANLAGVHRPRLIGNFLPEFGWHPIILTVKEAFFEETPDIDFKKTFRDHFEVHRVNAAPLSKFRVIGDIGIRSFWQLYQGAKKIITEKEIDFIWIPVPSYYPALLGRLLYSKYKIPYGIDYIDPWVRDMKNYPSSGIRQRLALAIAKFLEPIAVKKASLISGVAKAYYQDVLNRNDRDGEKIDVAMPYGFDPKDHEIELDIETPWSGEREIIPYIYAGAFLPNSVSFFHKFFAAIKKFRDRDKWNSKIKLYFIGTGLYPGTTIQEIANGYGLKDVVVEKKERLPFLNILYFLSQAKGVLAIGSPSPHYTASKIFQSVLSKRPVFAFFHEKSTVVGILNEANADQFLMTYSENDSETDLDVRLETILENYFLKDVDWQVNLEALNKYSAKASAQVLVEGFNKVLKNNNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKF2</accession>
    <name>A0A5C6ZKF2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aspartate aminotransferase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_02240</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="1 2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="375" mass="41144" checksum="E9BA5F854D7CA502" modified="2019-11-13" version="1">MNLFNVYPLYDVTPVSAKDVYVYDGKGVEYLDLYGGHAVISIGHSHPEYVSAICYQVEKLGFYSNAIQNPLQEELAKRLGRLSNCEDYQLFLCSSGAEANENALKLASFHNGKKKILAFNNAFHGRTSAAVAATDNPKIVAPLNAQQQVDFVALGDLEAVEAILKKEETCAVIIECIQGVGGLDESTSGFYQGLEKLCKQYNTVFIADEVQSGFGRTGDFFAFQKHGLTPDIISIAKGMGNGFPVGGILIHPEIKASFGLLGTTFGGNHLACVATLSVLKVLETEQLTENVKRVSDYFRSKTEGLPGLKSVKGRGLMLGLEFEFPISELRKALIYEHHIFTGSAKNPNLIRILPPLTIQEKHIDKLFEALRYELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKF8</accession>
    <name>A0A5C6ZKF8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_06365</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010559">
        <property type="entry name" value="Sig_transdc_His_kin_internal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06580">
        <property type="entry name" value="His_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="His_kinase" evidence="2">
        <location>
            <begin position="166"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="354" mass="41033" checksum="FFC9EDAF69CC9B6E" modified="2019-11-13" version="1">MYSKEFLLKKFGQLLLHVLFWAGVLFFYTYFFSFGTKAVSYVLSFSLFLMPITMATTYVSIYKLIPDYLITKRYLQFGVYSLYTLIISIYLIVISIFFGLVYLSNFESHKMAPISKNLLFVAIAVYLIVIVVSAFKILKINLNIAKKTKALETKILETQLQLKAQQLAYLKMQIHPHFLFNTLNTLYAFSLKQSKQAPDMILKLSNLLDYLLYQSDKPLVPIEEEVQHIKDYIALEKMRFNETLLIDFEMQPPHELLAIPPMLLLPFVENSFKHGAIIHGKLHIAILIETTPNSLVFSIKNSARVESITSEGIGLENIKKRLELLYPKHHDLKIETNKDEFKITLKLFLNEHSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKI1</accession>
    <name>A0A5C6ZKI1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein-export chaperone SecB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_02400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SecB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051262">
        <property type="term" value="P:protein tetramerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003708">
        <property type="entry name" value="SecB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035958">
        <property type="entry name" value="SecB-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02556">
        <property type="entry name" value="SecB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54611">
        <property type="entry name" value="SSF54611"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0653">Protein transport</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0811">Translocation</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="131" mass="15157" checksum="0AB6F0231F8BF203" modified="2019-11-13" version="1">MKIQLDNWKVINVNFSSLKDEPREDNSFDLSTGHFFPKEIDKSFGVGFEIEIKDKFFDLFVEAIFMFKLDEDITEEFKLSNFPKINAPAIAFPFLRAYVSNLTLQSGFDPVILPSINFVQFAKDKQESEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKK9</accession>
    <name>A0A5C6ZKK9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Small ribosomal subunit biogenesis GTPase RsgA</fullName>
            <ecNumber evidence="7">3.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">rsgA</name>
        <name evidence="10" type="ORF">ESY86_02105</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="7"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04466">
        <property type="entry name" value="S1_YloQ_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01854">
        <property type="entry name" value="YjeQ_EngC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01820">
        <property type="entry name" value="GTPase_RsgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030378">
        <property type="entry name" value="G_CP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004881">
        <property type="entry name" value="Ribosome_biogen_GTPase_RsgA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010914">
        <property type="entry name" value="RsgA_GTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031944">
        <property type="entry name" value="RsgA_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32120">
        <property type="entry name" value="PTHR32120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03193">
        <property type="entry name" value="RsgA_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16745">
        <property type="entry name" value="RsgA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00157">
        <property type="entry name" value="TIGR00157"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50936">
        <property type="entry name" value="ENGC_GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51721">
        <property type="entry name" value="G_CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CP-type G" evidence="9">
        <location>
            <begin position="80"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="ENGC_GTPASE" evidence="8">
        <location>
            <begin position="89"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="129"/>
            <end position="132"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="183"/>
            <end position="191"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="265"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="272"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD90777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="316" mass="35663" checksum="39782E40492D3925" modified="2019-11-13" version="1">MTGTVYKSTGSWYTVNTDLGASYQCRIKGKFRLKGIKSTNPIAVGDHVDFELETNNDVVTGVIHRIHDRTNYIIRKSVNLSKQTHIIASNIDQVFLLVTIDNPPTFTSFIDRFLVTAEAYSIKTVILFNKVDTYSNDTLDEVRFLAHVYRKIGYECIGISAETGKNVDQVKALMADKVSMFAGHSGVGKSTLINAIETNLDLKTKAISAQHQQGQHTTTFAEMFDLSFGAQIIDTPGIKGFGIVDMDKEEVGDYFPEFFKLKQDCKFNNCLHIEEPNCAVKNALDKDEVAYSRYKSYVQIIENDDENYRTDIWETQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKN0</accession>
    <name>A0A5C6ZKN0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF547 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_09070</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006869">
        <property type="entry name" value="DUF547"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04784">
        <property type="entry name" value="DUF547"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023027439" evidence="1">
        <location>
            <begin position="20"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="DUF547" evidence="2">
        <location>
            <begin position="68"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="235" mass="26782" checksum="742BDD386DEBACE8" modified="2019-11-13" version="1">MKLSTLFLLLFASFQMAKAQPLNDFFTEADQFFKSHVAEGKVDYDAIAKKPSALNKLMSRADAISVSKTNANAYKAFWINAYNLAVIKGVIDNYPIKSPLDTDGFFDKITYRLAGENLTLNAIENQKLRAQFNEPRFHFVLVCGAIGCPPLIDKAYTPKNLEAQLESQTKLALNNPEFIKVEADAVQLSEIFKWYKEDFVKNGSELDFINQFRSENINPECSISYYPYNWNLNKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKP8</accession>
    <name>A0A5C6ZKP8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05385</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022738763" evidence="1">
        <location>
            <begin position="23"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="122" mass="13638" checksum="99B9384ACD7F8D6D" modified="2019-11-13" version="1">MKKIVICSLVLLFISCSGNKDMSPPETAKVVAESFYHGDKAALKKHTTAEGYANLSSIQEMFAKDKNSESNFKIVDEAMDGEFVWIKYSTAYDPKPGVFKLVQEDGQWKVTHNGPRDKGPFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKW5</accession>
    <name>A0A5C6ZKW5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type II toxin-antitoxin system HicB family antitoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_03705</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035069">
        <property type="entry name" value="TTHA1013/TTHA0281-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008651">
        <property type="entry name" value="Uncharacterised_HicB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05534">
        <property type="entry name" value="HicB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143100">
        <property type="entry name" value="SSF143100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="117" mass="13208" checksum="EDD40A82A45D9707" modified="2019-11-13" version="1">MADYLKHKAYLGSVEFSAEDAVLHGKIIGINDLVTFEADSVDGIQKAFIEAVEDYLETCIALNKAPNKFYKGVFNVRTSNELHRDLALIAEKKQMKLNELVNKAFDFLVKNEDKVLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL16</accession>
    <name>A0A5C6ZL16_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="250" mass="29456" checksum="1A2DA39AEF2510DD" modified="2019-11-13" version="1">MNYIKLLNAAFEKFYFDDRLNPTHISLYMALFQEWNSSRFADEMYVNRRDLMRVAKIGSKSTYHRCITDLDAWGYLFYFPSNNPYKGSKIKMAIIGTSDEPVVGRYNPTLEQLAEHYHPIREPVVGQHRPINGQVVNQHRPVSGQALVSTINNNKQENNIKQPKGWQAVFNFFEEKGFDADEAKKFFEHYQTRNWQTSDGKEIRDWRALATNWMDRTELFDEENKLNKKQASQIKDNLRTTKNKDYGQPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL43</accession>
    <name>A0A5C6ZL43_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03135</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="56"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="144" mass="17093" checksum="BFF788EDC9A69E71" modified="2019-11-13" version="1">MKTTYSILLIFFVSASVFAQRLDKEKIKALKIAHITEQLNLTENEAQKFWPIYNTNEALEDQLRKQSTARRKEKNQEDLSETEAKSLLLDMVQLENDKQELQSKLVNDLLKVLPATKIIKLMQVERSFRRKLIEEYKERHSRRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL71</accession>
    <name>A0A5C6ZL71_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Arginine--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Arginyl-tRNA synthetase</fullName>
            <shortName evidence="9">ArgRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">argS</name>
        <name evidence="13" type="ORF">ESY86_04160</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg)</text>
            <dbReference type="Rhea" id="RHEA:20301"/>
            <dbReference type="Rhea" id="RHEA-COMP:9658"/>
            <dbReference type="Rhea" id="RHEA-COMP:9673"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78513"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.19"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="9">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 10">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.19" evidence="9"/>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004814">
        <property type="term" value="F:arginine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006420">
        <property type="term" value="P:arginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00123">
        <property type="entry name" value="Arg_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001278">
        <property type="entry name" value="Arg-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005148">
        <property type="entry name" value="Arg-tRNA-synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036695">
        <property type="entry name" value="Arg-tRNA-synth_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035684">
        <property type="entry name" value="ArgRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008909">
        <property type="entry name" value="DALR_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11956">
        <property type="entry name" value="PTHR11956"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03485">
        <property type="entry name" value="Arg_tRNA_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05746">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00750">
        <property type="entry name" value="tRNA-synt_1d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01038">
        <property type="entry name" value="TRNASYNTHARG"/>
    </dbReference>
    <dbReference type="SMART" id="SM01016">
        <property type="entry name" value="Arg_tRNA_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00836">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55190">
        <property type="entry name" value="SSF55190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00456">
        <property type="entry name" value="argS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arg_tRNA_synt_N" evidence="12">
        <location>
            <begin position="5"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="DALR_1" evidence="11">
        <location>
            <begin position="477"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="9">
        <location>
            <begin position="123"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TXD90569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="592" mass="67338" checksum="00EDCCBC1DC28DA3" modified="2019-11-13" version="1">MTLQETLGQQVKAAVRQHFGAEIETVEFQATRKEFAGDITVVVFPMLRVVKGNPAQIGEQIGLFLKQEMDLITDYNVVKGFLNLEINDRYYLDFFSKIQDDPQFAFLKPSENNKAVMVEYSSPNTNKPLHLGHVRNNLLGYSVAEIIKASGKKVYKTQIINDRGIHICKSMLAWQRFGNGETPASTNLKGDKLVGNYYVKFDQEYKKEIKHLIAEGKTEEEAKKEAPILLEAQQMLQQWEAGDTEVVALWNTMNTWVYDGFDVTYKNLGVDFDQLYYESQTYLLGKEFVAEGLQKGVFFQKEDGSVWCDLTEDGLDEKIVLRSDGTAVYMTQDIGTAIQRVKDFPDVGGMVYTVGNEQEYHFQVLFLIIKKLGFDWADNLFHLSYGMVDLPSGKMKSREGTVVDADDLIDEMTQTAAEISEELGKLDGYSSEEKKELYKTIGLGALKYYILKVDPKKRILFDPKESIDFQGNTGPFIQYTYARIQSILRKAEDAKEVNFSTLELHEKERELIKQLELFPEVIQNAAEHHSPALVANYTYDLVKGFNSFYQNVSILGADDDNEKAFRTQLARLVANTIKNAFGLLGIEVPERM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL86</accession>
    <name>A0A5C6ZL86_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DsbA family oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05265</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001853">
        <property type="entry name" value="DSBA-like_thioredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01323">
        <property type="entry name" value="DSBA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DSBA" evidence="1">
        <location>
            <begin position="6"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="215" mass="24647" checksum="C998CA5D9E4326EB" modified="2019-11-13" version="1">MTKKLKIDIISDVVCPWCTIGYKRLEKAISELGIQDQVNIEWHPFELNPNMPAEGQNVQEHITEKYGSTPAQQIESQQRMTEIGKELGFTFDYFDAMRMVNTFEAHVLLEYAKEFGKQTEMKMRLTRAFFSERKDVSDRAILKQAVLDVGLDAEGALARLDSEDARKDIRNQQDYWKNLGVNSVPTIVFNRKSAVTGAQPVRVFKEVLTELLEQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLA0</accession>
    <name>A0A5C6ZLA0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03455</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="L30e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013123">
        <property type="entry name" value="SpoU_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00967">
        <property type="entry name" value="SpoU_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="SSF55315"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SpoU_sub_bind" evidence="1">
        <location>
            <begin position="34"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="266" mass="29343" checksum="098D54E5846BF4EE" modified="2019-11-13" version="1">MAHKTISSSQNQFIKHLVVLKEKSRERKKSGLFLIEGQRELSLAIKGNYEIETLLFYPELCSETQLNDFKISQLKHIEISKEVFQKLAYRQTTEGIIAVAKAKRHTISDLHLSSKNPLILVAEAPEKPGNIGALLRTADAANVDAVIIANPKSDLYNPNIIRSSVGCVFTNTLASGTSEDIIAFLKSAKINIYCAALQDAVNYHQQDFTQATAIVVGTEAEGLSDAWREAATQNIIIPMQGQIDSMNVSVAAGILVFEAKRQRNFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLD9</accession>
    <name>A0A5C6ZLD9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">L-serine dehydratase</fullName>
            <ecNumber evidence="9">4.3.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">ESY86_06230</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>L-serine = NH4(+) + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:19169"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="EC" id="4.3.1.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 9">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the iron-sulfur dependent L-serine dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.17" evidence="9"/>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003941">
        <property type="term" value="F:L-serine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029009">
        <property type="entry name" value="ASB_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004644">
        <property type="entry name" value="Fe-S_L-Ser_mono"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005130">
        <property type="entry name" value="Ser_deHydtase-like_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005131">
        <property type="entry name" value="Ser_deHydtase_bsu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03313">
        <property type="entry name" value="SDH_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03315">
        <property type="entry name" value="SDH_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143548">
        <property type="entry name" value="SSF143548"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00720">
        <property type="entry name" value="sda_mono"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="6 9" id="KW-0408">Iron</keyword>
    <keyword evidence="7 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 9 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SDH_beta" evidence="11">
        <location>
            <begin position="5"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="SDH_alpha" evidence="10">
        <location>
            <begin position="188"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU366059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TXD89800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="475" mass="52284" checksum="15C2D6D09C9DD24B" modified="2019-11-13" version="1">MECISVFDMLKIGVGPSSSHTLGPWRAAERWIKKLKETKRFDKLEHIQVDLYGSLSLTGKGHATDLAVMLGLSGADPEHIPVDTIDVIISSIKNSNSLMLNNERKVAFDAKADIVFNKKFLPFHSNGMIFTATINGRHYKETYYSIGGGFVVQEERKISKMNKIIFYCTFPYPVENGVKLLEFCKQLNLPVSGVVLENEKSIRDEATIDFELERIWNTMLECMYVGCHTEGHLPGGLNVRRRAFDMHKNLINNDVPYETPLEWLESIRNNEVKFRQILKWVSCFALSVNEVNASLGRVVTAPTNGSAGVIPAVLMYYMTIENHEATFEHVKKFLLVAGEIGSIFKKGATISAAMGGCQAEIGVSSAMAAAALTELLGGTPEQVLVAAEIAMEHHLGLTCDPIGGLVQIPCIERNSMGAIKAINAAELALDTDPKNVKVPLDKVVQTMWETAKDMSSKYKETSEGGLAVGVHLSDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLF4</accession>
    <name>A0A5C6ZLF4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF4157 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_00475</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025295">
        <property type="entry name" value="DUF4157"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13699">
        <property type="entry name" value="DUF4157"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="204"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="241"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="277"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4157" evidence="3">
        <location>
            <begin position="115"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD91104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="326" mass="35533" checksum="2365AA4C89563475" modified="2019-11-13" version="1">MYTTQIKDTTRNRSVESVFIQPKLKIGSFNDKYEQEADRIAEQVVHGSNQTAQIQHTGSLVQRKCTACEAEELQMKPLSQQVTSLIQTKSNTSGQVASDLVSSGIQSSKGGGKSMDSSTKSSMENRFGSDFSSVNIHTGHKANHLNQLINARAFTVGNDIFFNKGEYQPNSSRGKYLLAHELTHTVQQGVVQRKMIQREPASTITLGALAAKCIIGAIIGVLFDLALQYGLHLWRRGERFVVDYCSLILSAALSCIAAPIVSYGVEAWLTSRLTNSAYSGIIGTLLGRILIFIGARLGMAVPKSMVGKLLRMGCISQQQNDALQAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLP8</accession>
    <name>A0A5C6ZLP8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidylprolyl isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_06565</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000297">
        <property type="entry name" value="PPIase_PpiC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027304">
        <property type="entry name" value="Trigger_fact/SurA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00639">
        <property type="entry name" value="Rotamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109998">
        <property type="entry name" value="SSF109998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50198">
        <property type="entry name" value="PPIC_PPIASE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0697">Rotamase</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022839853" evidence="2">
        <location>
            <begin position="19"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="domain" description="PpiC" evidence="3">
        <location>
            <begin position="120"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="PpiC" evidence="3">
        <location>
            <begin position="222"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="646" mass="74983" checksum="A5C173D14D7E7994" modified="2019-11-13" version="1">MKLLITAICLSFSVLIYAQEDKKDVLFTVDGEPVMTSEFQRVYNKNLDLVKDESQKDIDAYLELFVNYKLKVKDAKRLGLDKDAQYVKEFNNYKNQLSKNYMTDNKVTDKLVKEAYDRISNEVKASHILIMLDENETDTTQVYNRLLELRQRVLDEGFAPVQKEVHDRETVFAEDLGWFSGFKMVYPFETEAYNTKLGEVSMPFRSKFGFHIVKVWDKRKSLGEVAVAHIMIAKQQQDSTIDPETRIQQIYGKIEQGEKFESLAKQFSDDNSSSSKGGELAPFSGGQLSSKAFEDVAFSLENKNDISKPFQSEYGWHIIKLIDKKEMQSFEDMQSELESRVKRDSRSQLINSAMVKKLKEKYQIKDHPEALTYFAGTINEDFFKRTWNIPEQIESDKIILKIKDDSYTYRDFADYLMSAQRNYSNKPLKPEVVVNKEYEAFLERKLLQYQEAHLEEENEDFAHVLQEYRDGLLLFDLMEQEIWNKATKDSLGLQAFFDTHQSDYVWKDRADGSLLTSASEKEISKARKALKKGDSIEAVLTERNKNNASNILATNQVFEQGDQALPETYNFKNGISEIFEHNDAYHILITNEILPAGAKTLKEARGRVVSDYQNQLEKDWLTNLHERYTVEINKAALQQVKLKLQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLV6</accession>
    <name>A0A5C6ZLV6_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Plastocyanin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_05750</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022764061" description="Plastocyanin-like domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="2">
        <location>
            <begin position="52"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="134" mass="15178" checksum="77F045BAADEF2E79" modified="2019-11-13" version="1">MKSQLWLLATLLILSIKQSYAHCSTNELAIREHILKAEKQSGTKTDNYNASRTLYRSIPNPTLALNEDEQAVVYVTNRLAVAASVHWRVVCYPSFVGIGTPSADCPKFIFYSKRESLSVPAQRMCYQKRSYNAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLX0</accession>
    <name>A0A5C6ZLX0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_03195</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="86"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="119"/>
            <end position="126"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="384" mass="44193" checksum="4C516D020CB6283E" modified="2019-11-13" version="1">MTQAKLRIQEVNSFFKNKDTVLGYRKLMDCAIDTQDLAIYKKVIALTDWKSQHPEQEVAFIEKALSLLNEISKIPITEYQREKPVVVGENLIKSYGINRFELGPISTTIHKGEVYGLVGENGNGKTTLLRILAKEIGYDKGQLHYNFDSIYKSDYELRTNLVYIPQRTQKWYGSLKDNLKFVLSSYGIPPEENETRVLMMIARFGLWPYKHLKWNELSSGYKMRFELARTLLRQPELLLLDEPLANLDVLAQQVILEDLKSMCNSINKPIALILSSQQLYEVEKISDKVIYLRDGKYTDNNAMPSTDHKSQLIIEIDSELERDALTSVFVELQLEKLNYNGGIYVAYFNESTSFPSVLTALGTHKVNATYIRNITKSTRRFFVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM23</accession>
    <name>A0A5C6ZM23_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Riboflavin synthase subunit beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00670</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="95" mass="11036" checksum="0D66CE5B23522298" modified="2019-11-13" version="1">MGILNTRKNKKYSYQPRYYKGEGNPYELKHKFDDFRVTAGSDKGLKTKLNNAVGDYKYNADTNGANRRVVYIVAALILIFLFIIDFDLSIFFPNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM73</accession>
    <name>A0A5C6ZM73_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Cardiolipin synthase</fullName>
            <shortName evidence="12">CL synthase</shortName>
            <ecNumber evidence="12">2.7.8.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">cls</name>
        <name evidence="14" type="ORF">ESY86_03220</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>2 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) = a cardiolipin + glycerol</text>
            <dbReference type="Rhea" id="RHEA:31451"/>
            <dbReference type="ChEBI" id="CHEBI:17754"/>
            <dbReference type="ChEBI" id="CHEBI:62237"/>
            <dbReference type="ChEBI" id="CHEBI:64716"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cell membrane</location>
            <topology evidence="12">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the phospholipase D family. Cardiolipin synthase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.-" evidence="12"/>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008808">
        <property type="term" value="F:cardiolipin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032049">
        <property type="term" value="P:cardiolipin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01916">
        <property type="entry name" value="Cardiolipin_synth_Cls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030874">
        <property type="entry name" value="Cardiolipin_synth_Firmi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022924">
        <property type="entry name" value="Cardiolipin_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027379">
        <property type="entry name" value="CLS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13396">
        <property type="entry name" value="PLDc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00155">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04265">
        <property type="entry name" value="bac_cardiolipin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 12" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 12" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8 12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 12" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="11 12" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="13">
        <location>
            <begin position="220"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="13">
        <location>
            <begin position="399"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="225"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="227"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="232"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="404"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="406"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TXD90391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="486" mass="55602" checksum="D60DB8BC3016DA09" modified="2019-11-13" version="1">MLDFLKSHTWTILIVINYLVAISAIVVILLKNRNPTKTVSYILVLAVFPFFGIVVYYLFGQEYRKTKIFNRKDISNDKVVKTVGDQLRLNGRDLKAVDDLLDDKIKLVKLLKNSDKSPLTTNNSVEILRNGEVKFKHLFEDLKKAKHHIHIEYYVLEDHRIGTELLDIICAKAREGVEVKLVYDDVGSKMSSKMKRKLTECGVEHKPFMKVIFSSLAGRSNYRNHRKIVVIDGRIGYVGGINVSDDYVNFEENNNTRYWRDTHLKIVGDAVKVLQFHFITTWDFVTDGDIEIKTSYFPEITTDSAVAVQIAASGPDTDWANIMEALLTAINNAEQYVYITTPYFIPNDQIVTALQIASRIGLDVRLIIPKNSDSWIAENATNSYLEPLLDAGVKVYLYSKGFVHAKTMVVDDIFSTVGTCNMDNRSFNINFEINALIYNKEKALELKALFLEDLKDCEPLDVARWENRSTWCKFQESVSRLWAPLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM93</accession>
    <name>A0A5C6ZM93_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sigma-70 family RNA polymerase sigma factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_06105</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="27"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="3">
        <location>
            <begin position="131"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="194" mass="22968" checksum="97980D8F6FB006B9" modified="2019-11-13" version="1">MKHKDISDAVLVNRYINGDEQSLSILIYRHKQKIYSFIYSKVFDKDITEDIFQDAFIKVIKNLKLGKYNEEGKFLPWVMRISHNLVIDHFRKSNRMPKFDNSGDFNIFTVLGDPAMNAEKRLIKEQVDCDLRRLIEELPEDQKDVLIMRMYKEMSFKEISQQTDVSINTALGRMRYALINLRKIIEEKNIVLSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMR2</accession>
    <name>A0A5C6ZMR2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA starvation/stationary phase protection protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_01195</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the Dps family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016722">
        <property type="term" value="F:oxidoreductase activity, acting on metal ions"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01043">
        <property type="entry name" value="DPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002177">
        <property type="entry name" value="DPS_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023188">
        <property type="entry name" value="DPS_DNA-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008331">
        <property type="entry name" value="Ferritin_DPS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42932">
        <property type="entry name" value="PTHR42932"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00210">
        <property type="entry name" value="Ferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005900">
        <property type="entry name" value="Dps"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01346">
        <property type="entry name" value="HELNAPAPROT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00818">
        <property type="entry name" value="DPS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00819">
        <property type="entry name" value="DPS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ferritin" evidence="3">
        <location>
            <begin position="18"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD91232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="159" mass="18067" checksum="D0AAF91BBCB32234" modified="2019-11-13" version="1">MAKNSIGLDIQKTESIAKDLNHLLANFQIYYQNLRGIHWNIRGKRFFDLHVKFEELYTDANLKVDIIAERILTLGATPLHTFEDYTKAAKVPVGKNISEDEKAVRLIVDSLSELLKIERQILNASGEANDEGSNALMSDFISEQEKTVWMMKAWLGEGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN46</accession>
    <name>A0A5C6ZN46_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0675">Receptor</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Plug" evidence="1">
        <location>
            <begin position="110"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="811" mass="92240" checksum="4D369A75AE19B5B2" modified="2019-11-13" version="1">MFYGNSQTATIKGVILNDDNQPIPSVSISSGNLGTTSNDNGFFELKVPADEDVVVTFTHISHRNVVATFNLKNGQALEFNPVMKVEVEQIAAVVINTNTRQSVDGVLSISPEILRTIKGAQPGIENILKTLPGFNISNELSTQYSVRGGNFDENLVYVNEIEVYRPFLIRSGQQEGLSFVNTDMVQNVDFSAGGFQAKYGDRLSSVLDITYRNPINFGIRADASLLGGSVTAEAVSKDSKFSGIVGLRYRDNSLFINSLETESDVVPVFADVQTFLTYKFSDKFHLNFLGNISLNQYDFTPQNRQTNFGTLDEPVALQVFYEGQEKDKYLTTFGAFKANYFASEDLNLKLIASAYHTTEQEYFDILAQYRLGEVNTNIGDENLGEVEFTEGIGSQFTHARNDLDAVIVNIEHKGDYKLKDESTLEWSLKYTHEDLRDRLVEWEVIDSAGFSVRPPIFNIPNNQPYQPFEGPLTAFQNIRATNYVKIDRLQAYAQWSKRTMLGSNEVFYNAGLRAHSWNVNSEIPNEEGVSSSNQLVVSPRAQFAIKPDWEKDMMFRIAGGVYYQPPLYRELRDSSGIVQPDVKAQKSIHLVVGNEYSFKMWDRPFKLVTEAYYKHLSDVNPYTLENVRIRYRAKNNAKAYAYGLDLRLNGEFVPGTESWFSFGYLKTEENIENRGYIARPTDQRLKFGILFQDYVPNIPDLKMYLNLIYNTGVPGGSPSYADPYVYQSRLRDYRRADLGLSYVLVNQNKTYSAQWKQVFKELTLGVEIYNMFNAQNTISNTWVRDVYSKRQFAIPNFLTPRVFNVRLSTRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN48</accession>
    <name>A0A5C6ZN48_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 4">30S ribosomal protein S9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 5" type="primary">rpsI</name>
        <name evidence="5" type="ORF">ESY86_02030</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the universal ribosomal protein uS9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00532_B">
        <property type="entry name" value="Ribosomal_S9_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000754">
        <property type="entry name" value="Ribosomal_S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023035">
        <property type="entry name" value="Ribosomal_S9_bac/plastid"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21569">
        <property type="entry name" value="PTHR21569"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00380">
        <property type="entry name" value="Ribosomal_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00016789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="128" mass="14508" checksum="E5EB4CB02503D719" modified="2019-11-13" version="1">MEVIHKIGRRKTAVARVYLAAGEGKITINKKDMTDYFPSATLQYKVNQPLVMTNNDGNFDITVNVFGGGITGQAEAIRLAFSRAMCEIDAENRLILKPEGLLTRDPRMVERKKFGQKKARKKFQFSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN76</accession>
    <name>A0A5C6ZN76_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_00300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005182">
        <property type="entry name" value="DUF304"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014529">
        <property type="entry name" value="UCP026631"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03703">
        <property type="entry name" value="bPH_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF026631">
        <property type="entry name" value="UCP026631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="190"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="237"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="366"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="389"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="bPH_2" evidence="2">
        <location>
            <begin position="75"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="bPH_2" evidence="2">
        <location>
            <begin position="410"/>
            <end position="484"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD91075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="496" mass="56988" checksum="F13F288F368CB78D" modified="2019-11-13" version="1">MAAVDFSQPARQSSKGILVIFGVKAFKFIKSFFILFVAYGISMLQKKQLGISLGWIIFGFVLVILLLLVFSILKYLNFKFHVSADDFHLDTGVINKDNTVIPKSKIQNVYIKQNFLQQLINVVSLNIETAGDNKSEIEISALDKSTALALKTQLFTKIQADVAAEDLPKEADVFFKVSLKRLLMEGISQNHFKSFLIIVSFFFGLYSEFEKYLKELRLSERIEGAVRLDEQSLFNLFLVNLFLIVVLLLVSLVFSVVQTLVVNFNLEVLERERTLEIHKGLFNKMSLTLTPSRIQNLVIKTNRVKAYFNLYSLSVKQAMVNKKQQKNFTIVAMEKVQIDHLLNKLLESYSEETETHKPAPYYKRILWLRLVLIFAVLSGPAFLIFGNDFWLINLVFLLFGLVFVHYKFKKTYYQISEAHLTIGGGFIDTITNILETHKIQALQFKQTFFQKRNGIASVVVSTASKTVVIPYIKATDAKRIYDYLLFCVESQDRDWM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZND1</accession>
    <name>A0A5C6ZND1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Methyltransferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_03820</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001510">
        <property type="term" value="P:RNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001678">
        <property type="entry name" value="MeTrfase_RsmB/NOP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023267">
        <property type="entry name" value="RCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807">
        <property type="entry name" value="PTHR22807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01189">
        <property type="entry name" value="Methyltr_RsmB-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02008">
        <property type="entry name" value="RCMTFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51686">
        <property type="entry name" value="SAM_MT_RSMB_NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM_MT_RSMB_NOP" evidence="5">
        <location>
            <begin position="142"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="354"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="301"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD90503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="406" mass="46829" checksum="4ED4D378310A3ACE" modified="2019-11-13" version="1">MRLHRNLCFAIIDGLTLIFNEGKYADKVIQQLLRRDKRWGSRDRAFVAETTYDIVRWKRLYAEIAEVKEPFDRDNLWRMFAVWATLRGIKLPDWQYFENTPTRKIKGRFDELSQTRKYRESIPDWMDEMGEKALGDELWTKEIAALNEQADVVLRVNTLQTTKEKLKGELFDLNFDTEDIKGYPNALRLKERANVFQTEAFKNGNFEVQDASSQLVAEFLDVQPGMRVVDACAGAGGKALHLASLMDNKGQIIALDIYGNKLKELKRRAKRNGAFNIETRAIETTKVIKKLYDQADRVLIDAPCSGLGVLRRNPDAKWKLQPEFIEDIKKTQQGILQQYARIVKPGGKMVYATCSILPSENRMQVDDFLTSEIGKDFTFVKENNVFAHKSGFDGFYMALLERNNTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNK7</accession>
    <name>A0A5C6ZNK7_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Coenzyme A biosynthesis bifunctional protein CoaBC</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">DNA/pantothenate metabolism flavoprotein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Phosphopantothenoylcysteine synthetase/decarboxylase</fullName>
            <shortName evidence="3">PPCS-PPCDC</shortName>
        </alternativeName>
        <domain>
            <recommendedName>
                <fullName evidence="3">Phosphopantothenoylcysteine decarboxylase</fullName>
                <shortName evidence="3">PPC decarboxylase</shortName>
                <shortName evidence="3">PPC-DC</shortName>
                <ecNumber evidence="3">4.1.1.36</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="3">CoaC</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="3">Phosphopantothenate--cysteine ligase</fullName>
                <ecNumber evidence="3">6.3.2.5</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="3">CoaB</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="3">Phosphopantothenoylcysteine synthetase</fullName>
                <shortName evidence="3">PPC synthetase</shortName>
                <shortName evidence="3">PPC-S</shortName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="3 7" type="primary">coaBC</name>
        <name evidence="7" type="ORF">ESY86_01045</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.</text>
    </comment>
    <comment type="function">
        <text evidence="4">Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>(R)-4'-phosphopantothenate + CTP + L-cysteine = CMP + diphosphate + H(+) + N-[(R)-4-phosphopantothenoyl]-L-cysteine</text>
            <dbReference type="Rhea" id="RHEA:19397"/>
            <dbReference type="ChEBI" id="CHEBI:10986"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:59458"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="EC" id="6.3.2.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>H(+) + N-[(R)-4-phosphopantothenoyl]-L-cysteine = (R)-4'-phosphopantetheine + CO2</text>
            <dbReference type="Rhea" id="RHEA:16793"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:59458"/>
            <dbReference type="ChEBI" id="CHEBI:61723"/>
            <dbReference type="EC" id="4.1.1.36"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="3">Binds 1 FMN per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 2/5.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 3/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">In the C-terminal section; belongs to the PPC synthetase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.36" evidence="3"/>
    <dbReference type="EC" id="6.3.2.5" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00241">
        <property type="reaction ID" value="UER00353"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004632">
        <property type="term" value="F:phosphopantothenate--cysteine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004633">
        <property type="term" value="F:phosphopantothenoylcysteine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015941">
        <property type="term" value="P:pantothenate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02225">
        <property type="entry name" value="CoaBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035929">
        <property type="entry name" value="CoaB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005252">
        <property type="entry name" value="CoaBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007085">
        <property type="entry name" value="DNA/pantothenate-metab_flavo_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036551">
        <property type="entry name" value="Flavin_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003382">
        <property type="entry name" value="Flavoprotein"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04127">
        <property type="entry name" value="DFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02441">
        <property type="entry name" value="Flavoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102645">
        <property type="entry name" value="SSF102645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52507">
        <property type="entry name" value="SSF52507"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00521">
        <property type="entry name" value="coaBC_dfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3 4" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="3 4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 4" id="KW-0288">FMN</keyword>
    <keyword evidence="3 4 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 3 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavoprotein" evidence="5">
        <location>
            <begin position="7"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="DFP" evidence="6">
        <location>
            <begin position="189"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphopantothenoylcysteine decarboxylase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphopantothenate--cysteine ligase" evidence="3">
        <location>
            <begin position="194"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="293"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="327"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="341"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="345"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD91205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="403" mass="43287" checksum="248C149417AED0BD" modified="2019-11-13" version="1">MSILSGKNILLGITAGIAAYKTASLTRLFIKAGANVKIVMTPASKDFITPLTLSTLSKNPVYSSFTNEEDDNAMWNNHVELGLWADLLIIAPATANSLSKMANGTCDNLMMATYLSAKCPVYFAPAMDLDMHKHPSTLKSFEILNDFGNVMIPATSGELASGLHGEGRMAEPEAIVAFIEQHILDQLPLRGKKVLLTAGPTHEAIDPVRFIGNHSSGKMGFEIAKASAALGAEVILISGPTHESVNNSAIKLINVVSAQEMYDAAHRYFNDVDIAILSAAVADYRPKKVASQKLKKDDSSLSLELERTQDILKSLGAIKKHQYLVGFALETMNELANAKSKLASKNLNMIVLNSLNDTGAGFGGSTNKVTFITNSGQELSHALKSKAAVAQDLMQFILKQTHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNU5</accession>
    <name>A0A5C6ZNU5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_00015</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="63" mass="6739" checksum="4A15A9F33776207E" modified="2019-11-13" version="1">MKSSLKSPLTSVVHVDDFVIGGPEEGEKGRSKGRQKLIVLAIEVLENGVGRAYAELIENSSAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZP76</accession>
    <name>A0A5C6ZP76_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Signal peptidase I</fullName>
            <ecNumber evidence="3">3.4.21.89</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">lepB</name>
        <name evidence="5" type="ORF">ESY86_00635</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>Cleavage of hydrophobic, N-terminal signal or leader sequences from secreted and periplasmic proteins.</text>
            <dbReference type="EC" id="3.4.21.89"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the peptidase S26 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.89" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06530">
        <property type="entry name" value="S26_SPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043739">
        <property type="entry name" value="DUF5684"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000223">
        <property type="entry name" value="Pept_S26A_signal_pept_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019533">
        <property type="entry name" value="Peptidase_S26"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43390">
        <property type="entry name" value="PTHR43390"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18936">
        <property type="entry name" value="DUF5684"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10502">
        <property type="entry name" value="Peptidase_S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00727">
        <property type="entry name" value="LEADERPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="SSF51306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02227">
        <property type="entry name" value="sigpep_I_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="498"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S26" evidence="4">
        <location>
            <begin position="124"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR600223-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD91131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="525" mass="61214" checksum="0A95C7AAC6937DB2" modified="2019-11-13" version="1">MTITQWFIFILVIQIIHGLATWKLYQKAGRQAWEAFVPIYNAVILMKIIRRPWWWTILLFVPIVNLIMFPVVWVETARSFGKNQYLDTFLAIVTLGFYNFYLNYVADVHYIENRDLHPKSSSGDWVSSILFAIVAATIVHTYFIQPFTIPSSSLEKSLLVGDFLFVSKFHYGARIPMTTVAAPMVHDTIPFLNKKSYLFDDHKEKNKTSWKNKLQLPYMRLPGFEDIERNDIVVFNQPADTLLNMNDFNPDRNYYKPIDKKTNLVKRCVGIPGDSLEVRDGLVFINGKQNELPDRALLQFDYDIVFKNISSDEQVYSMLKRYDITDRVGFDPKQESYYIQASPQAVAQAINHPNIVSITRRSTPKDYDQNLFPREPQFPWSYNNFGPIYIPKKGVTVDLNLDVLPLYNRLISEYESNDLKVRGNQILINGQAATSYTFQQNYYWMMGDNRNNSIDARAWGYVPFDHVVGKPVFIWMSWDGLKNPRWERWFTTVGGSGKAISFFIPFLILLAVIFAFNKFRKRKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPL4</accession>
    <name>A0A5C6ZPL4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Histidine ammonia-lyase</fullName>
            <ecNumber evidence="3 6">4.3.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">hutH</name>
        <name evidence="8" type="ORF">ESY86_01465</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>L-histidine = NH4(+) + trans-urocanate</text>
            <dbReference type="Rhea" id="RHEA:21232"/>
            <dbReference type="ChEBI" id="CHEBI:17771"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="EC" id="4.3.1.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 6">Amino-acid degradation; L-histidine degradation into L-glutamate; N-formimidoyl-L-glutamate from L-histidine: step 1/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PAL/histidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.3" evidence="3 6"/>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00379">
        <property type="reaction ID" value="UER00549"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004397">
        <property type="term" value="F:histidine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019556">
        <property type="term" value="P:histidine catabolic process to glutamate and formamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019557">
        <property type="term" value="P:histidine catabolic process to glutamate and formate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00332">
        <property type="entry name" value="PAL-HAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001106">
        <property type="entry name" value="Aromatic_Lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005921">
        <property type="entry name" value="HutH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022313">
        <property type="entry name" value="Phe/His_NH3-lyase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10362">
        <property type="entry name" value="PTHR10362"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00221">
        <property type="entry name" value="Lyase_aromatic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01225">
        <property type="entry name" value="hutH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00488">
        <property type="entry name" value="PAL_HISTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0369">Histidine metabolism</keyword>
    <keyword evidence="5 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD91281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="503" mass="55785" checksum="A9D8C5618CC4FBC4" modified="2019-11-13" version="1">MKETHYISTETLDIETIRDLILFDKKISLSKASEEKILNCRNYLDDKVAKEESAIYGINTGFGSLYNVKISKDKLVQLQENLVMSHACGIGDKVPEPIVKLMLFLKIQSLSYGHSGVQLQTVQRLIDFYNNDVLPVIYTQGSLGASGDLAPLAHLALPLLGKGEVYFKQKVTDASVALAHFSWSPIELKSKEGLALLNGTQFMSAYGVHLLIASYKLSYMADLIGSMSLEAFDGRIEPFKALIHLVRPHKGQLKTAERIREFLDGSELISQKKQHVQDPYSFRCMPQVHGATKDTLDYVKKVFITEINSVTDNPNIFVADDEIISGGNFHGQPLALALDYLKIAMAELGNISERRTYQLVSGLRGLPMFLVDNPGLNSGFMIPQYTAASIVSANKQLATPASIDSIVSSNGQEDHVSMGANAATQAHQLIVNVNRILGIELLNASQALFFRKPVQSSPFIESFLKTYRTEVKFVSEDQILHNLIKASEGFLKNMHIENNLLFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZR75</accession>
    <name>A0A5C6ZR75_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PpiC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_00390</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000297">
        <property type="entry name" value="PPIase_PpiC"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50198">
        <property type="entry name" value="PPIC_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0697">Rotamase</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022767827" description="PpiC domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="PpiC" evidence="3">
        <location>
            <begin position="94"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD91090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="211" mass="23825" checksum="AC9C1C04B1BB6C64" modified="2019-11-13" version="1">MFKTLLPAACLLIATATFAQDDFEKSLDLVQTETDANTFLENNTASEGKVIVFNKEKHKTRLAKELFSLGLGAKTYDKNNLQPTYYKVIEKTSTAYYKASVIFFDASVKSLEAINYSRNAIISKYRRGVRFENLARNYSMDQTAKQSGDLGWITKGSLHPKLENAIFEGKHKVNDIFAVDVPETNAYYLVVITEAEKMIDEIKVLKVTEPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZRF0</accession>
    <name>A0A5C6ZRF0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00855</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046111">
        <property type="entry name" value="DUF6048"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19515">
        <property type="entry name" value="DUF6048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022741880" evidence="1">
        <location>
            <begin position="25"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="250" mass="28216" checksum="2905BBCC3897885B" modified="2019-11-13" version="1">MKMKYTISFTISLVVLMLLPKISASQDNNESTQDTLVYKQKYGLRLGVDIGKVIRSFADSDYTGFEINADYRFSKRIYLAGELGTEEKTIANEYLNVTASGTYFKAGFDYNTYTNWLDMQNMIFTGFRVGASSFSQTLNEFTVYDTNQAFFNQTYTARPGDEFNGLSAIWAELVIGLKAELFANLFMGVNMQIKGRISQDEPVGFENLFIPGFNRTYDSGGIGVGFGYTLSYLIPIFKKDKLIVVEKPKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6Z9J1</accession>
    <name>A0A5C6Z9J1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Matrixin family metalloprotease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_20265</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000062">
        <property type="protein sequence ID" value="TXD86418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031012">
        <property type="term" value="C:extracellular matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001818">
        <property type="entry name" value="Pept_M10_metallopeptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021190">
        <property type="entry name" value="Pept_M10A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00413">
        <property type="entry name" value="Peptidase_M10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00138">
        <property type="entry name" value="MATRIXIN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023100956" evidence="1">
        <location>
            <begin position="20"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M10" evidence="2">
        <location>
            <begin position="40"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="134" mass="14791" checksum="59AF0A920D06ADA2" modified="2019-11-13" version="1">MKKIIFLLLAFILTNSISAQILYDNGAIDDPNNFTLDGRNWDHTNLTYFFENGTTDITNNDEHIAVEQAMAIWETSSEITFTEVNNASNADIVIRWATGNHGDGSNFDTTGGVLAHAFFPPPNSGSLAGDMDFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6Z9P8</accession>
    <name>A0A5C6Z9P8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_20605</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000093">
        <property type="protein sequence ID" value="TXD86101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="301" mass="34568" checksum="413DDCCD0A44D299" modified="2019-11-13" version="1">MKKFLPLLIVMIGLTSCKENTKKQTASDETLNSIDNSVELTEEQKDLKKNAIPIQNLSKLSDKIYDEIANYEIIMIGEMHGTNEPAEFAYGLCELIAKHEGSVIMAMEIRASLMNNLSDEMSISELKELDFFRGKNFDGRNGIAWLDLVYKGIKNDGIILKFIDNPYPSSTRDSSMYREIRNIHNKHPNTKIVTLTGNTHNSFIPLFNKERIGGYLLKDTVNFDSKKIMSINHVFSEGNMLNNDLTGLKMRTIEREENIYNTTLSYEIFLYKKLLEEQNRCTHILYTDKVTASEIIKKDDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZA85</accession>
    <name>A0A5C6ZA85_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20405</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000071">
        <property type="protein sequence ID" value="TXD86298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022676511" evidence="1">
        <location>
            <begin position="19"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="107" mass="11909" checksum="38F55D565B3903BC" modified="2019-11-13" version="1">MKRIVFLFMMSLTFSAFSSNSISEIKVDCNSITNKIDYNFTEIDNNSYTFNEDFGWGVTCYVIIQNQVTGEERKVSGSGTGATPGLALQDCGKNARKNAKELYNIVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBC3</accession>
    <name>A0A5C6ZBC3_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">1,4-dihydroxy-2-naphthoate octaprenyltransferase</fullName>
            <shortName evidence="5">DHNA-octaprenyltransferase</shortName>
            <ecNumber evidence="5">2.5.1.74</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 6" type="primary">menA</name>
        <name evidence="6" type="ORF">ESY86_17230</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>1,4-dihydroxy-2-naphthoate + an all-trans-polyprenyl diphosphate + H(+) = a 2-demethylmenaquinol + CO2 + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:26478"/>
            <dbReference type="Rhea" id="RHEA-COMP:9563"/>
            <dbReference type="Rhea" id="RHEA-COMP:9564"/>
            <dbReference type="ChEBI" id="CHEBI:11173"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:55437"/>
            <dbReference type="ChEBI" id="CHEBI:58914"/>
            <dbReference type="EC" id="2.5.1.74"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Quinol/quinone metabolism; menaquinone biosynthesis; menaquinol from 1,4-dihydroxy-2-naphthoate: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the MenA family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.74" evidence="5"/>
    <dbReference type="EMBL" id="VORO01000026">
        <property type="protein sequence ID" value="TXD87305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00079">
        <property type="reaction ID" value="UER00168"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046428">
        <property type="term" value="F:1,4-dihydroxy-2-naphthoate octaprenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd13962">
        <property type="entry name" value="PT_UbiA_UBIAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01937">
        <property type="entry name" value="MenA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004657">
        <property type="entry name" value="MenA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026046">
        <property type="entry name" value="UBIAD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13929">
        <property type="entry name" value="PTHR13929"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005355">
        <property type="entry name" value="UBIAD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0474">Menaquinone biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="98"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="120"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="154"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="178"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="225"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="250"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="281"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD87305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="301" mass="33218" checksum="2DC10902BA73FEA5" modified="2019-11-13" version="1">MFKKIQPWLSAFRLRTLPLSVSGIILGSCFGYSIGAFDGWIMFLAILLTISLQVLSNLANDYGDGVRGTDNENRLGPTRAIQSGAITPDEMISGIKKNVLLIVVLTLLLIFTAFKDEYLGYALLFFVLSAAAVYAAINYTVGRSPYGYRGLGDIFVFLFFGVMSTVGSYFLYSKQLDFYVLLPAVSVGLFSVGVLNLNNMRDIESDALSNKRTLAVILGSKNAKIYHLALIILAMMVALMFSVIHFSSLWNLLFLLAYIPMSIHIVKIYKARSAPDYDSQLKVLALSTFLFSVLLGVGYIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBE7</accession>
    <name>A0A5C6ZBE7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA-binding response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_20610</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000094">
        <property type="protein sequence ID" value="TXD86091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="3"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="251" mass="28887" checksum="94E80527AA591843" modified="2019-11-13" version="1">MIRYILVDDEPTTLAFVKTKIDGIAKDFNLKHVKSYSSSLKAFEEVIEEDYDLLIVDFEMSPYNGIELAKKIAENKKVVFLTSTSNNGPKMMNALDVSGYLSKPFDLEEFKDIIKHKVIGKINPTKVSQKPHTITLSIGTNKDVRFPSNQAYYMRTSRNINGEQPNKNCVHIYGKNDVVLYANLRISINELYEKLADYNFEKVDQSNIINMDYLKERDNMHIELQDCSETFEVTAKHKPGFIANLRAKLMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBN5</accession>
    <name>A0A5C6ZBN5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase s41</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_17840</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000028">
        <property type="protein sequence ID" value="TXD87176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00245">
        <property type="entry name" value="TSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022972867" evidence="1">
        <location>
            <begin position="24"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="domain" description="TSPc" evidence="2">
        <location>
            <begin position="223"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="484" mass="55602" checksum="22D2820A29F16381" modified="2019-11-13" version="1">MKQFHKISISLSLLFLPFLHLQAQDCSCEDSFETAVNAYEKNYSLFMYKVTDENRDLYNAHTDLMLAKAKQTEDLQDCKVLLERWLDFFRDGHTYIVMSTEQVTETYNESIQITEKQFKADYQKKSYERNPLLGIWKSGAYTVAILPNPKSSIRERDYVGVILESENPEWKKGEVKLELSSEFGNSYQINFMMGDHSLEKTSGQQTDLAVIEIDGLGKWMKIWPEVENSKKRSEIELKYDKFHISYIDDIPYLRLPDFYSVDPSYVDSLMQTHHDRILKSDFMIVDIRGNGGGNDATYFPVLPYVLSGPVEIPSNGFWLSEDNTEYLISAMAASKGFTVEEYKEKDKKEYDMFNDNRGTAYFKGNGKWTFTADTIYNSPKKVILLTDKEVGSSGETFVYRANQSDRVVVYGQNTAGVVDGFNGFPFDIGCFTVVFPTSYRAPDLKENPIDPYGIAPDVYVDEKEDVLAYAIEHMKQLIKNEVSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC01</accession>
    <name>A0A5C6ZC01_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dihydrofolate reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_19005</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000035">
        <property type="protein sequence ID" value="TXD86901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039461">
        <property type="entry name" value="Peptidase_M49"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23422">
        <property type="entry name" value="PTHR23422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03571">
        <property type="entry name" value="Peptidase_M49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="588"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="588" mass="66233" checksum="662CAD3B8856EFBA" modified="2019-11-13" version="1" fragment="single">MKLKWIMGLAVIAGLMNACKAEKNDLKPATVQTEQTDAFDYNVEQFADIKILRYQIPGWENLSLKEKKLVYFLTQAGLSGRDMIWDQNYRYNLTIRKALENVYANYAGDKSSADWSAFETYMKRVWFSNGIHHHYSNEKMKPEFSSEYLKQLLADTNTTLEGEAFEVLFNDQDSKKVDLTKGGDNVKLSAVNFYGPNVVNADVEAFYKTKTSPNPEKPLSFGLNSKLVKENGTLKELTYKSGGLYGTAIDEVVKWLEKAKEVAENPEQGKALGLLIDYYKSGDLQTWDDYNVAWTAATEGNIDYINSFIEVYNDPLGYTGSYETIVQIKDFDMSQKMEVLSENAQWFEDNAPLMEAHKKENVVGVTYKVVNVAGEAGDASPSTPIGVNLPNANWIRAAVGSKSVSLGNIINAYNNAGSSGRLKEFVNDDEEFELEEKYGQLADKLHTALHEVIGHASGQLNPGVGETKETLKSYASTLEEGRADLVGLYYLYSPKLQELGLVDDWKSVGKAAYDGYIRNGLMTQLIRLKIGDNIEEAHMRNRQWVAAWAYEKGMKDNVIEKITRDGKTYFNINDYEKLHAIFGELLRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC84</accession>
    <name>A0A5C6ZC84_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20435</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000074">
        <property type="protein sequence ID" value="TXD86287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="163" mass="19339" checksum="C67859134D99BFFA" modified="2019-11-13" version="1">MRNRIWAELTQSKHNIEFTSTYSDRQRFVLRIFNMGILAFSSAGIMGWKIWENLPLIACIVIAGISLLRLLQPHLIMNEKQLKNLDDIHRFYADYYNRIEKLWYDFESGRITEEQATKVFFKIKKLETDINPIIAETIRSKPKGIVKKCKKNTDEYFKLVFNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCA3</accession>
    <name>A0A5C6ZCA3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19865</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000051">
        <property type="protein sequence ID" value="TXD86566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041657">
        <property type="entry name" value="HTH_17"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12728">
        <property type="entry name" value="HTH_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_17" evidence="1">
        <location>
            <begin position="39"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="94" mass="10631" checksum="3D43E099F383B183" modified="2019-11-13" version="1">MPTSIITTDDLRDFKMELLDDIKKLLTNQSKGKVKKYVKSSEVMDLLQVSPGTLQNLRINGTLPYTKVGGIIYYDTEEIQNVMDANRVQHGLNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCA9</accession>
    <name>A0A5C6ZCA9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Apolipoprotein N-acyltransferase</fullName>
            <shortName evidence="8">ALP N-acyltransferase</shortName>
            <ecNumber evidence="8">2.3.1.269</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">lnt</name>
        <name evidence="10" type="ORF">ESY86_16755</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the phospholipid dependent N-acylation of the N-terminal cysteine of apolipoprotein, the last step in lipoprotein maturation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>a glycerophospholipid + N-terminal S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[lipoprotein] = a 2-acyl-sn-glycero-3-phospholipid + H(+) + N-acyl-S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[lipoprotein]</text>
            <dbReference type="Rhea" id="RHEA:48228"/>
            <dbReference type="Rhea" id="RHEA-COMP:14681"/>
            <dbReference type="Rhea" id="RHEA-COMP:14684"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:136912"/>
            <dbReference type="ChEBI" id="CHEBI:140656"/>
            <dbReference type="ChEBI" id="CHEBI:140657"/>
            <dbReference type="ChEBI" id="CHEBI:140660"/>
            <dbReference type="EC" id="2.3.1.269"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Protein modification; lipoprotein biosynthesis (N-acyl transfer).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the CN hydrolase family. Apolipoprotein N-acyltransferase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.269" evidence="8"/>
    <dbReference type="EMBL" id="VORO01000024">
        <property type="protein sequence ID" value="TXD87429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00666"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016410">
        <property type="term" value="F:N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042158">
        <property type="term" value="P:lipoprotein biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07571">
        <property type="entry name" value="ALP_N-acyl_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01148">
        <property type="entry name" value="Lnt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004563">
        <property type="entry name" value="Apolipo_AcylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045378">
        <property type="entry name" value="LNT_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20154">
        <property type="entry name" value="LNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00546">
        <property type="entry name" value="lnt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 10" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="161"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="189"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="505"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="domain" description="CN hydrolase" evidence="9">
        <location>
            <begin position="223"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD87429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="528" mass="59864" checksum="CC4DB2F0F5139ADE" modified="2019-11-13" version="1">MNKFLLALISGLLLALAWPTYGFPLLLFFAFVPLLLAEQQWRHSDSKRKGLKIFAASYLTFFIWNLVTTSWLRHADLFGASFAVLVNSALMAALILLYHYYSRRQSLNRSLLFLVALWISFEKMHLAWEFSWPWLNLGNGFSEYISWIQWYEYTGTFGGTLWVWLVNVLVFKGVLAYRKAGSKTLLKSVLLKTAAFIIVPIAISLVIYYNYEEEGETVNIIALQPNIDPYSEKYKVSNLKFAELFKDLSDSKISDSTDFVIAPETYFAQSIRLPQFDKSLLKNKLQQYVSAHPQINLLTGISFIDDFHDPERVGPQTNQYGANTWYNDYNSAIFINTSDSVAQYNKSKLVVGVENFPYQSILKPLIGDAMIDLGGTVSMKTTQDYRGVFTSSNGKFKAAPIICYESVYGEFVTGYVRNGANFLTIITNDAWWGETQGHKQHLSLARLRAIETRRAIARSANTGISAIINAKGQITKQLAYGQKGALSGSLIVNEKETFYVLAGDYIARIAIFVMIFVLLIGFFRKERV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCN7</accession>
    <name>A0A5C6ZCN7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TetR/AcrR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_19230</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000038">
        <property type="protein sequence ID" value="TXD86788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="22"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="205" mass="23949" checksum="81CD9F92C3D9E94D" modified="2019-11-13" version="1">MRDTIIHKSAELFINFGFKSVTMDDIANQLGISKKTIYQHFANKTKLIEATTNFMFDTISCGIDEIRELDKNPIAEIYEIKQFVMEHLKNEKSSPQYQLQKYYPKIFSSLKLKQFEIMQDCVTHNLHRGVALGLYREHINIQFISRIYFNCMIALKDQELFPLKDFSMSSLMDNYLDYHLRGICTIKGLELLNTNTSQPTNNTPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCS4</accession>
    <name>A0A5C6ZCS4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_16765</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000024">
        <property type="protein sequence ID" value="TXD87431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="77" mass="9119" checksum="320DAF527002974A" modified="2019-11-13" version="1">MNLETRKIEFVQEFLKLQSEDAIARLEKLLEQQKMTPDQKRLAPMTQAELNNRIDQSESDFLNNRYKSSAELLAKYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCY2</accession>
    <name>A0A5C6ZCY2_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5 6">50S ribosomal protein L20</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">rplT</name>
        <name evidence="7" type="ORF">ESY86_18755</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the bacterial ribosomal protein bL20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000033">
        <property type="protein sequence ID" value="TXD86966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07026">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1900.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00382">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005813">
        <property type="entry name" value="Ribosomal_L20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035566">
        <property type="entry name" value="Ribosomal_protein_L20_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10986">
        <property type="entry name" value="PTHR10986"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00453">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00062">
        <property type="entry name" value="RIBOSOMALL20"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74731">
        <property type="entry name" value="SSF74731"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01032">
        <property type="entry name" value="rplT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00937">
        <property type="entry name" value="RIBOSOMAL_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD86966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="114" mass="13164" checksum="983246E478335CDC" modified="2019-11-13" version="1">MPRSVNSVAKRARRKKVLKQAKGYFGRRKNVWTVAKNAVDKAMQYSYRDRRVKKRTFRSLWIMRINAGARQHGMSYSKLMGGLKANNVNLNRKVLADLAMNHPDAFEAVVNKVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD02</accession>
    <name>A0A5C6ZD02_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TIR domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18535</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000032">
        <property type="protein sequence ID" value="TXD86992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003953">
        <property type="term" value="F:NAD+ nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019677">
        <property type="term" value="P:NAD catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13676">
        <property type="entry name" value="TIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="SSF52200"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50104">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TIR" evidence="1">
        <location>
            <begin position="146"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="415" mass="49139" checksum="EE261F1C4DA0656C" modified="2019-11-13" version="1">MEIEIDFPRNEFIKELENYIQEGKDLHKKFKLLPVNPDNLESLEREFIYWTEEVQEFLKIRLATIFENEFLTKFEGTNRIDFKPIVNAFAGEKVDVVKNKYVHTLNQTKKKLVVLNLLKRKTKFMKTVEYYSESTTEHDTLNRKKEMKEIFISHSSLDSKYVEKLIDIFEAIGVPSDKIFCSSFEGYGVRLGNDFLEDIRKRLNSNVLVVFILSENFYSSVVSLCEMGATWVKTNNHIPVLIPPFDYSDVKGVIPTTNGMKINEKAKYNSLKNVIEDFLDLKPINNSVWERKRDNSLKDLKVLLETVVYSTVNEKPKRTKQTEENLELNFYDNQDDIIKSKSQKEWPDDFEMQLDYIDRHKNAIVKLKKHNPIDIEQGKFIIIRTNGRKEWPDDFEMQLDYEQRQVESLRRLNER</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD18</accession>
    <name>A0A5C6ZD18_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_16725</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000023">
        <property type="protein sequence ID" value="TXD87537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="171" mass="19589" checksum="4C85F92C31C7729A" modified="2019-11-13" version="1">MENKEQIKNSENRLAKIQGNIDNTLEKSKEVVNIAKEGTQMVSEVTNNIQDTFNKANNLFQGVKGLKDSFMESQKLQAQTEIELLKIRSEHQQMNRIITEEYGKQKQSMDKASDVVDAGLESNDINKIREGLTAMTNVANHNPMENHKKALDNELERNLNQDFDDDFTLEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD34</accession>
    <name>A0A5C6ZD34_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_18195</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000030">
        <property type="protein sequence ID" value="TXD87064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041682">
        <property type="entry name" value="AAA_14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025420">
        <property type="entry name" value="DUF4143"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13173">
        <property type="entry name" value="AAA_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13635">
        <property type="entry name" value="DUF4143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_14" evidence="1">
        <location>
            <begin position="17"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4143" evidence="2">
        <location>
            <begin position="183"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="375" mass="43753" checksum="9E6480A841276DB6" modified="2019-11-13" version="1">MILREISKLLEQKIKDSKIIILVGPRQVGKTTLLKTMFKTEATLWLNGDDADVRSKLSNTSSTYLKQLVGTHDRLIIDEAQRIENIGLTLKILHDQLPEVKVLATGSSAFELANQINEPLTGRKWEFHLWPISFEEMANHHSLLEEERLLEHRLVYGWYPEVINNPGSEKLILNALSDSYLYKDILTWEDIKKPQKLEALVQALAFQIGQQVSYHELGQIVGLNNETVERYINLLEKAFIIFRLPSLSRNLRNELKKSRKIYFYDVGIRNSVIKNWNPVAMRQDVGALWENFLIVERLKHKSYNQLFSNDYFWRTHAQQEIDFIEESGGVLHAYEFKWNPKRKAKFSKAFKDGYPNHELSVVNKTNFLDFVQKPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDD7</accession>
    <name>A0A5C6ZDD7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">SIMPL domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_14630</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="337" mass="38489" checksum="94A528EB6FB86FB6" modified="2019-11-13" version="1">MCFHKIFFFSILASTSVFSNAQHKGNYDLLSRQNILHSGNATIYNPVIQQQLQKVLNPSTTIYIDVKALQNEAATTYTAIFNISQIVPTADSTTVLSNQRIEQVRKKLQAVGISKNDLVIDVISFVPNYELEIEKKLFSKTYTEVPKGFELQENLHIRFTKTSQFESILSACAANEIYNLVKVDYYIDNIAEVYKNLEVQLLELITQKKAYYNTLGFDLNNYDVAIADDRYCYFPKDFYQSYQAYNSISFDAIKRKKGVTTAKKQSSYYYQPLSNETFDLVIKPSVLEPVVQIGMNIKLQYTAKAAKPQPAVNTEIKHKYYIVSPNGPIDIKALQTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDI5</accession>
    <name>A0A5C6ZDI5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">rplE</name>
        <name evidence="9" type="ORF">ESY86_14890</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uL5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01333_B">
        <property type="entry name" value="Ribosomal_L5_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002132">
        <property type="entry name" value="Ribosomal_L5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020930">
        <property type="entry name" value="Ribosomal_L5_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031309">
        <property type="entry name" value="Ribosomal_L5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022803">
        <property type="entry name" value="Ribosomal_L5_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031310">
        <property type="entry name" value="Ribosomal_L5_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11994">
        <property type="entry name" value="PTHR11994"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00281">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00673">
        <property type="entry name" value="Ribosomal_L5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002161">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55282">
        <property type="entry name" value="SSF55282"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L5" evidence="7">
        <location>
            <begin position="27"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L5_C" evidence="8">
        <location>
            <begin position="87"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD87953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="183" mass="20261" checksum="FBE86DB617B8A220" modified="2019-11-13" version="1">MAYTPRLKKEYQDKVVTALTEEFGYKNVMEVPKLKKIVLSKGVGAAVADKKLIDHAIDELTAITGQKAVATLSKKDVASFKLRKGMPIGVRVTLRGEQMYEFLDRLITSALPRVRDFTGIKATGFDGRGNYNLGVVEQIIFPEMNIDKINKISGMDITFVTSAATDKEAKSLLTEMGLPFQKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDL8</accession>
    <name>A0A5C6ZDL8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 4">Cryptochrome DASH</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_14530</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">May have a photoreceptor function.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
        </cofactor>
        <text evidence="4">Binds 1 5,10-methenyltetrahydrofolate (MTHF) per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="4">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the DNA photolyase class-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003913">
        <property type="term" value="F:DNA photolyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014133">
        <property type="entry name" value="Cry_DASH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036134">
        <property type="entry name" value="Crypto/Photolyase_FAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036155">
        <property type="entry name" value="Crypto/Photolyase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005101">
        <property type="entry name" value="Cryptochr/Photolyase_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002081">
        <property type="entry name" value="Cryptochrome/DNA_photolyase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006050">
        <property type="entry name" value="DNA_photolyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455">
        <property type="entry name" value="PTHR11455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00875">
        <property type="entry name" value="DNA_photolyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03441">
        <property type="entry name" value="FAD_binding_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00147">
        <property type="entry name" value="DNAPHOTLYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48173">
        <property type="entry name" value="SSF48173"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52425">
        <property type="entry name" value="SSF52425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02765">
        <property type="entry name" value="crypto_DASH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51645">
        <property type="entry name" value="PHR_CRY_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0157">Chromophore</keyword>
    <keyword evidence="3 4" id="KW-0274">FAD</keyword>
    <keyword evidence="2 4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Photolyase/cryptochrome alpha/beta" evidence="5">
        <location>
            <begin position="2"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00017881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD88098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="467" mass="54326" checksum="C40E7A302B43152D" modified="2019-11-13" version="1">MKTGLVWFKNDLRLHDNEALCQAIAQCERVVCCFCVEASIFEELPLGFRKSGSNRFRFLEQSVLDLQQQLKKIGGQLIISSNGAEQDIPELIEIYAIDSIFAEKEYASEELKRIKHLKMSLPEVEFNFYWGKTLYHLNDIPFSIEKIPLTSKAYRIPTSKESTPRASFKAPEAIRPHPKAKSNAFPSIKNYGFDKVAYKKSAPFLAGGETEALARLKYYSFESESLTGYRWTRNKSQGLDYSSKFSPYLALGCLSPRTIYETVKAYETQIKRNQSTWWLIFELVWRDYFTFKGMKFGDLIFKTEGFKNKQVNFENNQIHFKRWQDGQTGIPFIDAHMRQLNQTGYMSNRGRVNCASYLVQDLKIDWNWGAAYFECQLIDYDVSSNWMNWHMQAYEIYYTNPVHQSLKYKAEAYIAQWIPELATLESAKIHAPWLYPEALKAVDYPEPIAVYPKWSRAIARIEKAVSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDT0</accession>
    <name>A0A5C6ZDT0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NAD(P)-dependent alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_17600</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000027">
        <property type="protein sequence ID" value="TXD87249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029752">
        <property type="entry name" value="D-isomer_DH_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00065">
        <property type="entry name" value="D_2_HYDROXYACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PKS_ER" evidence="4">
        <location>
            <begin position="10"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD87249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="334" mass="35578" checksum="B6463420333AB04E" modified="2019-11-13" version="1">MKVSAFAAKGPNQKLEAFSYEMGALGPEQVDVKILNCGVCHSDLSMMNDEWGMTSYPIVPGHEIIGEVVAAGNAVKSIKVGDKVGVGWYSASCMSCHECMDGSHHLCSSAEYTIGGRHGGFANYVRSHWSWAILLPEGINLAKAGPLLCGGITVFNPILIADVKATDKVGVIGIGGLGHMALKFLNKWGCEVVAFSSNPSKKESILAMGATKVVDSTNPEALAKIAGTLNFILNTTNVTLDWNSYLVALAPKGKFHNVGAVLEPMAIPAFTLLTGEKSVAGSPLGSPALTRTMLEFCVRHDIYPITEEFPMSKVNEAIAHLESGKARFRIVLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE19</accession>
    <name>A0A5C6ZE19_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Xanthine dehydrogenase family protein molybdopterin-binding subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_13270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000674">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036856">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016208">
        <property type="entry name" value="Ald_Oxase/xanthine_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008274">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037165">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11908">
        <property type="entry name" value="PTHR11908"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01315">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02738">
        <property type="entry name" value="Ald_Xan_dh_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01008">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54665">
        <property type="entry name" value="SSF54665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56003">
        <property type="entry name" value="SSF56003"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ald_Xan_dh_C" evidence="1">
        <location>
            <begin position="24"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="726" mass="79510" checksum="77B337F0D50879E0" modified="2019-11-13" version="1">MTKTINASGVGTAINRVEGHLKVMGKAKYATEFPVENKVYGQGINSTIAKGEIISIDTSEAEKLDGVLKIITYKNAEKLKDFDKEMTPIATDTIAPVLQSNKVHYYGEYVGLVVAETFEQAQYAASLVKFEYKKDPSAVIDFEKSKSKAYTPDNGSNYSRGNMEQGLSEADSVVEQTYNTPIEHHHPMELHAVIASWDNGKVTAYSSQQIVEDAKIAISGTFQIPKKDVRVISAFVGGGFGSKLNLDRHVIMGVMASKMVGRPVQVTVTRTQMFTNTNMRQQNEQKIRVGAKKDGTLTALSHETLSHTATNQEYQEPCGMVSKMLYKVPNNEVTYKLIPMNIQVPFAMRAPGEATGSFALESAMDEMAWKLKMDPLEFRIKNDTQTDLHENRPFSSRLLVECLRIGADKFGWKDRKPEPRTNKKGNWLIGYGVSAASRNSPYQKTHSKVILKLDEDKVFATIQMDATDIGTGSYTIIAQTASEYLKIPVEQVSVELGDSDFPITPGSGGSWGAASYCNGARAACENAIKTLKNNGNIAEDEEVAVSELLKKNQLTKFEAEGMAEPSAEFAKYSVFSFGANFCEVWVDKDTGMYRIEKMVNVASAGKILNPKTAYGQIIGGLTMGVGMVMAEQTHVEPNFGNFITRSFADYHVPVNLDMANIDVIFLPEEDKVANKMGIKGIGELGITSVAASIANAIFNATGKRMRSLPITPEKLIVAGLEPGITA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEG3</accession>
    <name>A0A5C6ZEG3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_17965</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000029">
        <property type="protein sequence ID" value="TXD87115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="251" mass="29678" checksum="3A98A9AC12B8BA9C" modified="2019-11-13" version="1">MDLYIESKDGILVEDIYVCYQLTNVIDLEKLHDLGFSICLDEELAFRPSTEYLMVKAQYELLGFELEHFKTPIKFDKLFNWYDGFRYLRNFFDGLDPFSSLDYKLFDDASRLLGKLDRIVSIKTITENALEALIDFQVATTERDKLIWLFENQMDRYANINFSIPEDLSVDSCVTYESDQLQLIIDITGYEYVFDYFKKLDDFYEAMMEKYKPLPAHFENSKQHRIGYSLESYLTLHKVHLDLVESYGQNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEJ9</accession>
    <name>A0A5C6ZEJ9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Tryptophan synthase alpha chain</fullName>
            <ecNumber evidence="7">4.2.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">trpA</name>
        <name evidence="9" type="ORF">ESY86_16355</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine = D-glyceraldehyde 3-phosphate + H2O + L-tryptophan</text>
            <dbReference type="Rhea" id="RHEA:10532"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.2.1.20"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 5/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Tetramer of two alpha and two beta chains.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the TrpA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.20" evidence="7"/>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00044"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004834">
        <property type="term" value="F:tryptophan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04724">
        <property type="entry name" value="Tryptophan_synthase_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00131">
        <property type="entry name" value="Trp_synth_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018204">
        <property type="entry name" value="Trp_synthase_alpha_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002028">
        <property type="entry name" value="Trp_synthase_suA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43406">
        <property type="entry name" value="PTHR43406"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00290">
        <property type="entry name" value="Trp_syntA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00262">
        <property type="entry name" value="trpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00167">
        <property type="entry name" value="TRP_SYNTHASE_ALPHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="6 7 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="45"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD87604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="254" mass="27825" checksum="F769B6190DE91A70" modified="2019-11-13" version="1">MNRINEKLNKDGKLLSIYFSAGYPNLSDTASIIQDLEKNGVDMIEIGLPFSDPLADGPTIQASSTAALKNGMTSDVLFNQLKDIRKTVSIPLIIMGYFNPMLQYGVEAFCAKCKEVGVDGLIIPDLPVDVYDEQYKSVFKKHGLINVFLITPQTSKERIDYIDSISEGFIYMVSSASVTGSGDGFGDAQTAYFKRISDLNLKHPQIVGFGIKDEHSFKQATTHAKGAIIGSAFIKHLTSHGTEKISDFVENIKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEL9</accession>
    <name>A0A5C6ZEL9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SMP-30/gluconolactonase/LRE family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013658">
        <property type="entry name" value="SGL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005511">
        <property type="entry name" value="SMP-30"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08450">
        <property type="entry name" value="SGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01790">
        <property type="entry name" value="SMP30FAMILY"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGL" evidence="1">
        <location>
            <begin position="56"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="337" mass="37520" checksum="49CEB0ECC13C60F0" modified="2019-11-13" version="1">MNQKTKMLPLSKQHTIFMKPLLYLFLFIAISSCKTKILPQVKQYEASLEYETKSQLGEGAFWNHKTQELYWVDIEGMQLHIYSPQTKTNRSLEMPSRIGTVVPSAVNAKAVVALQDGIYNIDVHSGDLELVSEIERDIPSNRFNDGKCDPSGRLWVGSMALDQKQYEANLYMVTENGEATLKKDSVTISNGIVWTKDKSTMYYIDTPTLEIKAYDYDDATGAITNERVAVTVNESLGFPDGMTIDANDMLWVALWNGNAVVNYNPKSGKLLSKVEVPAHNVTSCAFGGPNLDVLYITSSSLDMTEDEKEQYPFAGSLFKVKLDVKGVKGDFFGSAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEN5</accession>
    <name>A0A5C6ZEN5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cyanophycinase</fullName>
            <ecNumber evidence="4">3.4.15.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ESY86_14280</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[L-4-(L-arginin-2-N-yl)aspartate](n) + H2O = [L-4-(L-arginin-2-N-yl)aspartate](n-1) + L-4-(L-arginin-2-N-yl)aspartate</text>
            <dbReference type="Rhea" id="RHEA:12845"/>
            <dbReference type="Rhea" id="RHEA-COMP:13728"/>
            <dbReference type="Rhea" id="RHEA-COMP:13734"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:137986"/>
            <dbReference type="ChEBI" id="CHEBI:137991"/>
            <dbReference type="EC" id="3.4.15.6"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase S51 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.15.6" evidence="4"/>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044260">
        <property type="term" value="P:cellular macromolecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005320">
        <property type="entry name" value="Peptidase_S51"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011811">
        <property type="entry name" value="Peptidase_S51_cyanophycinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03575">
        <property type="entry name" value="Peptidase_S51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF032067">
        <property type="entry name" value="Cyanophycinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02069">
        <property type="entry name" value="cyanophycinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0720">Serine protease</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="147"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="189"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="8">
        <location>
            <position position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR032067-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD88052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="290" mass="31439" checksum="0B3D7BE779255657" modified="2019-11-13" version="1">MLSATHKPNKGTLIPIGGNEDKGLAEDDSHVLDYVKEGILAHVVRESGGPDAKILVVPAASSIPVEVGENYLSAFGTLGCKNVTVMQTKNKLETDTPEHLELLKQADCVMFSGGDQTKISKKIKDTKFHELLLEKYHNEQFVIAGTSAGAMAMANEMIAGGSAKEAFIKGAVRMYKGLALIPELIIDTHFIQRGRFGRITEAVAQFPQLVGLGLAEDTGLIIKNNRFEVIGSGMVIVFDGRRLIHNNHAILDPGTPLSITGLRTHILSNGDRFNIKNKKVEVLPMEASFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEZ8</accession>
    <name>A0A5C6ZEZ8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">TraR/DksA family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_13830</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000962">
        <property type="entry name" value="Znf_DskA_TraR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01258">
        <property type="entry name" value="zf-dskA_traR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51128">
        <property type="entry name" value="ZF_DKSA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DksA C4-type" evidence="6">
        <location>
            <begin position="55"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="dksA C4-type" evidence="4">
        <location>
            <begin position="98"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="39"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00510"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD88174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="126" mass="14296" checksum="C064E1DCEDB4F747" modified="2019-11-13" version="1">MTQENTERYSDNNLGEFKLLIQDKIVKAQRDLDLIKSAYMNDGDNGTDDTSPTFKAFDEGSAVSSKESNSQLAIRQEKFIRDLKNALIRIENKTYGICRVTGKLINKERLKLVPHATLSIEAKNMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFA2</accession>
    <name>A0A5C6ZFA2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">JAB domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_14755</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the UPF0758 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08071">
        <property type="entry name" value="MPN_DUF2466"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025657">
        <property type="entry name" value="RadC_JAB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001405">
        <property type="entry name" value="UPF0758"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020891">
        <property type="entry name" value="UPF0758_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30471">
        <property type="entry name" value="PTHR30471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04002">
        <property type="entry name" value="RadC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00608">
        <property type="entry name" value="radc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01302">
        <property type="entry name" value="UPF0758"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MPN" evidence="7">
        <location>
            <begin position="110"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD87926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="232" mass="25545" checksum="B9EE5829396EECA8" modified="2019-11-13" version="1">MADKPVFISIKNWSQDDRPREKLRDKGKANLSDAELIAILLGTGSRSESAVSLSQRILSSVDNNLNQLGKLSIKQLMTFRGIGEAKAITIVAAMELGRRRRGEEALEKMKISSSTSVFELMQPIIGELPHEEFWIVYLNNSNKVLHKNQVSKGGITGTLVDVRLVLKSALELGAVGLILAHNHPSGTLKPSTADKDLTKKLKLAAESLDIKVLDHLIITEKAYFSFADENIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFD5</accession>
    <name>A0A5C6ZFD5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Replication-associated recombination protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_14775</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family. RarA/MGS1/WRNIP1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032423">
        <property type="entry name" value="AAA_assoc_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021886">
        <property type="entry name" value="MgsA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16193">
        <property type="entry name" value="AAA_assoc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12002">
        <property type="entry name" value="MgsA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="SSF48019"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="2">
        <location>
            <begin position="38"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="426" mass="47692" checksum="BE6F6B4B84B1FE3D" modified="2019-11-13" version="1">MTAPLAERLRPETLDDYLSQNHLIGEKGVLRQQLQQGVIASMIFWGPPGTGKTTLANIVANESKRPFYTLSAINSGVKDIREVIDKAKQSGGLFTTKNPILFIDEIHRFSKSQQDSLLQAVEKGWVTLIGATTENPSFEVIPALLSRCQVYVLNSFSKDDLEALLKRAMEKDDILSRRKITLKETEALIRFSGGDARKLLNLFELIVTSYSEETPVVITNTEVAKRIQSNTVRYDKTGEQHYDIISAFIKSIRGSDPNAAVYWLARMIEGGEDVKFIARRLLILASEDIGNANPTALVIANNAFQAVSVIGYPESRIILSQCVTYLATSAKSNASYEAIGKAQQLVKQTGDLSVPLSLRNAPTKLMKELGYGDNYQYAHRYEQNFVPHEFLPDAIKSTKLYEPGDNAREQAQRDFLKARWKEKYGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFE6</accession>
    <name>A0A5C6ZFE6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">FtsX-like permease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_13380</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="277"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="324"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="371"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="415"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="666"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="715"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="749"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="20"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="310"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="426"/>
            <end position="630"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD88295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="786" mass="87119" checksum="1EA112B2A9C6EC03" modified="2019-11-13" version="1">MIRNYIKIAWRNLWKNKGYSFINIFGLAIGITCASLILLWVEDELNFDQSIPDKELVFAIPTNQKYDGEWRTFFEATPGPLASVLKSEIPEITKSARKRDVGQLLSVGEKSVNSAGSFADEDLINIFGLNFIAGNSKEAFKDKKSVILTEKAASVFFDKSEDAIGKNIQFDKKDTYTITGVVADFPENTTYTFDWLVPFENFTDGKEWTQGYGANFTNTFVKLAPDVNVANVNEKVKAILPAKTGDAETEAILFSANDWHLRDKFVNGKIDGGRIEYVRLFSFIALIILVIACINFMNLSTARSEKRANEVGMRKALGSGKKQLIFQFLTEAVMTAFISGIVSVALLIALIPQFNALIEKDLSLAITEPIHVLPIVFITLFCGIISGLYPAFYLSSFKPIEVLKGNRRQSGSASFTRKTLVVIQFSISIIFIISTILVYQQVQHIKNRNLGIVKENLIEMPAANGDIIKNFKSIEQALISSGLVESAALMNSQILSGGNNTSGVDWQGKPSDADILISIRTITPQFFNTAGMKIKEGKGFGTSEDADSTKVLISESFAKLMDTDNVVGNRINYNGQILTINGVVKDFLYGDMYGTSDPVMFYHQAEEANYMYIKPAAGAAINKTLTKIEDVLKTQNPGFPFEYRFVDEAFNERFKSEQLVENLSQIFAMLAIIISCLGLFGLSAFTAEQRRKEIGVRKVLGSSVLGIVKLLSKDFLKLVLLSILVSVPISWYVMQNWLQGFAYRIDIKLWVFAIAGLSAVLIALITVSFQAVKAAIANPVKSLRTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFG5</accession>
    <name>A0A5C6ZFG5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">30S ribosomal protein S13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 8" type="primary">rpsM</name>
        <name evidence="8" type="ORF">ESY86_14945</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.910.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01315">
        <property type="entry name" value="Ribosomal_S13_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027437">
        <property type="entry name" value="30s_Rbsml_prot_S13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001892">
        <property type="entry name" value="Ribosomal_S13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_S13-like_H2TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019980">
        <property type="entry name" value="Ribosomal_S13_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018269">
        <property type="entry name" value="Ribosomal_S13_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10871:SF1">
        <property type="entry name" value="PTHR10871:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00416">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002134">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="SSF46946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03631">
        <property type="entry name" value="uS13_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00646">
        <property type="entry name" value="RIBOSOMAL_S13_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50159">
        <property type="entry name" value="RIBOSOMAL_S13_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5" id="KW-0820">tRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="94"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD87964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="124" mass="13967" checksum="EB22129418D5FF31" modified="2019-11-13" version="1">MARIAGVDIPKQKRGVISLTYIYGVGNSRSQEILATAKVDESIKVEDWTDEQIGAIREAVGTFKIEGELRSETQLNIKRLMDIGCYRGIRHRAGLPLRGQRTKNNSRTRKGRRKTVANKKKATK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFK0</accession>
    <name>A0A5C6ZFK0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">FMN-binding negative transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_14750</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD88004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007396">
        <property type="entry name" value="TR_PAI2-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35802">
        <property type="entry name" value="PTHR35802"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04299">
        <property type="entry name" value="FMN_bind_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF010372">
        <property type="entry name" value="PaiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="196" mass="22465" checksum="DE3E8696D3D23E81" modified="2019-11-13" version="1">MTYPPPKHQEDDKNRLIEVIKTYPLATLISVADGLPLITHLPLIYERGRLIGHIDKMNPQTHLLKDQIDVTVLFSGPECYISPSIFSSTHLPTWNYIKVHLKGKVTAIDDQAALKASLISMTEALEAPDHKYVLDANNPRMDQNLKYIQLFEIHIESWEGKFKLSQDKAPKDIRHAREALLRSQQLSIENFLDKVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFR6</accession>
    <name>A0A5C6ZFR6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2490 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12115</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019619">
        <property type="entry name" value="DUF2490"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10677">
        <property type="entry name" value="DUF2490"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022930963" evidence="1">
        <location>
            <begin position="20"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="229" mass="27004" checksum="334EE263337E0ECB" modified="2019-11-13" version="1">MKKYLLVIITFLLSYQISAQVDESKIGAWYMYFFNHQFKNSQFGIQGDVQHRNWNVIGDLEQLLIRTGFTYTPKDTNVLLTLGYANITTGAFGDADETTGENRMYQEVLFPQKLGNRIYLTHRFRYEQRFVEDQDFRTRYRYNLFLNIPINKSALDKGAIYTALYNELFINGQEDIGDGRTVELFDRNRTYLGMGYVLREGQRIQLGWMNQKTDAWGKGQLQFSFHHNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFX7</accession>
    <name>A0A5C6ZFX7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Gliding motility-associated C-terminal domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_12355</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026341">
        <property type="entry name" value="Bac_Flav_CTERM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044023">
        <property type="entry name" value="Ig_7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19081">
        <property type="entry name" value="Ig_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04131">
        <property type="entry name" value="Bac_Flav_CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022879902" evidence="1">
        <location>
            <begin position="32"/>
            <end position="1418"/>
        </location>
    </feature>
    <feature type="domain" description="Ig_7" evidence="2">
        <location>
            <begin position="1241"/>
            <end position="1320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1418" mass="145212" checksum="16521039755790E6" modified="2019-11-13" version="1">MKARPYRLKSYPKVSVFILFLIAFGSQIANAQCPTVTNPTQTFCDVESVLIGDLVATDNGGGIVWYESATSTTPIPNNAGLNNNEDYYAGDTSGSCANRQRVDVIIFGPPSGQNFQGVCLDNPSNATVADLVANGNDVRWYSAPAGGTALSSSAVLMDNSIYYADQANPNSGCRTSRLSVLVNVGSTPVPEGDTTQDFCVTPTSIPTVGDLVASGMNNWYPSLSSALPLALETPLENGRTYYATTVDPPCESTARLAVFVTFTNRPDPGTNGNVDLCENNATVDLFSILGGTPDSGGIWSPTLTSGTGVFDPALDPEGVYTYSLAAEAPCEATSANVTVSLVPQPIAGNDGAITLCSDGETVNLFESLGGNPQPGGTWSPALNSGSGIFNPATDPEGVYTYTVSGTAPCDDVTANVTVSVGILPIAGSSASIEICDNIATIDLFNSLGGNPDVGGTWSPALASGSGVFDPSIDAEGTYTYTVLGTAPCPNASATVTLTITEFPDAGTNGAIELCSDDATVNLFNSLGGTPEAGGTWSPALSSGTGLFDPSVDAQGNYTYTLAGTAPCPNATAVVSVSVIVAPNPGENASVEICGDNETIDLFNSLGSSADTGGTWSPSLNSGTGIFDPSIDAEGTYTYTLLGTAPCSDASANVTVTIVPFLDAGLNGNITLCTNDAPVNLFNSLNGTPQNGGTWSPSLNSGSGLFNPSIDAEGTYTYTQTGTASCPDASAQVTVSLEVVPDAGQNGSLQLCGDSAVVNLFDSLGGTPDGGGTWSPALSSGTGFFDPNVDAEGVYTYTQLSPTALCDDDIATVTVSISEESDAGENASVTICTNTGAMDLFNSLGGTPQAGGTWSPTLNSGSGLFDPALDAEGVYTYTITGISPCPDDSATVNVSIETVPDAGLDGSLQLCSDNAPVNLFDSLGGTPEAGGTWTPTLTSGTGVFDPNSDTQGSYTYTISSVSGACPDNSAIVTVTVTEAADAGLDAAIDLCSNVTSVDLFNSLGGTPEPGGVWSPTLASGAGIFNPNLDPAGTYTYTIIGTAPCSEVSANVTVSIQPLPNAGNDLTLDVCRDGVPVDLFEELEAAEPGGIWTPALDSGTGVFDPLVDTAGTYTYTVTSSSCLLSDEASVVVILKDSPDVTGAILATDLNLCLGSSAVAIVIGATQLADGVYTIVYQLTGANTATNVVNITVEGGNSTFTIADANFENAGLTTVTVTGFFFAGENCTGDVSLIDAISVNIQDPETPQLIAGGATFCSEDNPNPTIADLTGNIVQSGSILWYDLPENGTAYTMTDALVDGQTYYATLVTANGCESSVRLEVTVSSSTCIKELTIPDGFSPNGDGINDDFHIVNLETLFPNFKLSVFNRYGNILYEGNSSSQRWDGTSRKGDSILPVGVYFYILEFNDGERSPQQGRVYLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG01</accession>
    <name>A0A5C6ZG01_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">YqaE/Pmp3 family membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_10920</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0057 (PMP3) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000612">
        <property type="entry name" value="PMP3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21659">
        <property type="entry name" value="PTHR21659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01679">
        <property type="entry name" value="Pmp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01309">
        <property type="entry name" value="UPF0057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD88993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="50" mass="5535" checksum="28E150DC20140768" modified="2019-11-13" version="1">MSLLTIILCILLPPLAVFLNHGLGKEFLISLLLTFVGWLPGVIYAFYVNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG18</accession>
    <name>A0A5C6ZG18_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">30S ribosomal protein S21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpsU</name>
        <name evidence="6" type="ORF">ESY86_16245</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the bacterial ribosomal protein bS21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00358">
        <property type="entry name" value="Ribosomal_S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001911">
        <property type="entry name" value="Ribosomal_S21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038380">
        <property type="entry name" value="S21_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01165">
        <property type="entry name" value="Ribosomal_S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00976">
        <property type="entry name" value="RIBOSOMALS21"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00030">
        <property type="entry name" value="S21p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD87587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="64" mass="7604" checksum="05B5E7C36786ABFF" modified="2019-11-13" version="1">MLIIPIKEGEQIDRALKRYKRKFDKTGTKRSLNERKQFTKPSVARRTQVQKAQYVQGLRDIENV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG87</accession>
    <name>A0A5C6ZG87_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">VWA domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_14625</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022838991" evidence="2">
        <location>
            <begin position="23"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="3">
        <location>
            <begin position="47"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="322"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD87902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="384" mass="42940" checksum="807AE55125970292" modified="2019-11-13" version="1">MKTRFKTGIVLFSLLYFLCCNANGKKQDNLLALAETPSSAPYKQSIKVALLLDTSNSMDGLIDQAKSQLWDIVSELSYAKCGKDKPNLQIALYEYGNDNLAAAEGHIRQIIAFSTDLDEISKHLFSLNTNGGNEFCGQVIETSLNQLSWGTNEADLKLIFIAGNEPFTQGKISYRDAAEQAKRNHVSVNTIFCGDYDQGIATSWQEGALLSNGNYMAINQNRTTTYVSTPYDDQILELNQKLNTTYVAYGSYGHKKMALQAEQDSNANGYSKENAVSRTVSKSSHLYKNSNWDLVDASNKKDFKIEDLDTSALPKALIGKSAQEIEAYIAQKKQERNSINEDIQNLNEKRRSYLSEQENTTDDNLENVMIKAIKTQAKAKNYTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGC5</accession>
    <name>A0A5C6ZGC5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MBL fold metallo-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12025</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="265" mass="30017" checksum="92E21C2719CBC67A" modified="2019-11-13" version="1">MKTNTLLLMFFLALLSACKTEKKEVGEKDMNTNTPEMQKSENASQKELKISPIEHATMVLTYGDDQIFVDPTKGVEAFKKFSAPQIVLITDIHADHFDLETLKALNLKNTTIVAPKAVADLFPKDFRYGKLIILDNGETQNIMGYDIEAIPMYNLREEALKFHPKGRGNGYVINFGSKRIYISGDTEDISEMRNLKDIQVAFVCMNLPYTMTVESAVSAVLEFKPDKVYPYHYRGTDGLSDIEKFKTMVNKGDESIEVVALDWYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGH7</accession>
    <name>A0A5C6ZGH7_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ATP-dependent 6-phosphofructokinase</fullName>
            <shortName evidence="9">ATP-PFK</shortName>
            <shortName evidence="9">Phosphofructokinase</shortName>
            <ecNumber evidence="9">2.7.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Phosphohexokinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">pfkA</name>
        <name evidence="11" type="ORF">ESY86_13550</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6-bisphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16109"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the phosphofructokinase type A (PFKA) family. PPi-dependent PFK group II subfamily. Atypical ATP-dependent clade 'X' sub-subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.11" evidence="9"/>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00182"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003872">
        <property type="term" value="F:6-phosphofructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01981">
        <property type="entry name" value="Phosphofructokinase_II_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022953">
        <property type="entry name" value="ATP_PFK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000023">
        <property type="entry name" value="Phosphofructokinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035966">
        <property type="entry name" value="PKF_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012004">
        <property type="entry name" value="PyroP-dep_PFK_TP0108"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00365">
        <property type="entry name" value="PFK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000534">
        <property type="entry name" value="PPi_PFK_TP0108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00476">
        <property type="entry name" value="PHFRCTKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53784">
        <property type="entry name" value="SSF53784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 9" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="6 9 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="7 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PFK" evidence="10">
        <location>
            <begin position="75"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="201"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="246"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="356"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="203"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="147"/>
            <end position="148"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="172"/>
            <end position="175"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="302"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for substrate specificity; cannot use PPi as phosphoryl donor" evidence="9">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD88323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="434" mass="46779" checksum="0FDDCC8CBCAC5283" modified="2019-11-13" version="1">MDFTVSTLGEPSVQSPISLSTIKGDKIFNFVSEAEKILLSVSLKAFNEHNGAPASLEKAGPRAHIFFDPTKSTAAIVTCGGLCPGINNVIRSLVMGLHYFYGVQRILGIPYGYEGLIPEYGHGFIDLVPDKVKDIHEFGGTILGSSRGGQNVSDMVDTLENNNIDILFAIGGDGTLKGANAIGEEIKKRGLKISVVGIPKTIDNDIDIIDKSFGFETAFDVASPIVKDAHNEATGAYNGISIVKLMGRDSGFIAASVAISIPVVNFVLIPEMKFDLQGDDGFLNALEARLDLKHHAVIVVAEGAGQDLFDKDQSEVKDASGNIQHSDIGLLLKDKIKDHFDSKDKRVVIKYIDPSYIIRSAPANASDSVFCNRLAYQALHGAMAGKTCFVVGVVNGQFVYLPIPAVTQKRKKIDLEGEFWFAALQSTGQPFVME</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGI9</accession>
    <name>A0A5C6ZGI9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_13570</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="166" mass="19071" checksum="C3814B3DF5658ABB" modified="2019-11-13" version="1">MKIINKNFSTFYLIFFFSVFSFSQSTITIKLLVDTENFDENDLSKSCSFEATWSDSSKVVRSNGDLEDFTIEASEDDTIIWEGSSTSSNTAIIDIKKIDQENASKIFKNKKIYGKKRGNSKKETAEARVLYNTKGKPDYKYKIFFKINQRGKTHKIDPKIKVLSKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGN3</accession>
    <name>A0A5C6ZGN3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_15145</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD88002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="261" mass="30688" checksum="E95D1F43C2522695" modified="2019-11-13" version="1">MIFAIGFTNLTFAEVKMDTITNWQLYKDSELLFKSHFLDSNRYTAKINSTDKYENLVLSVFYDFNNEVIDRKIELVCDNQIIATFKNESNSRSKFRIPKSEIDKLFSKNLNKEISINYSDKINGNGFTIGLLKLFVTEYTQLSIPEIRQIVQMAIDLPELQQYFHIDKSPNRKPLIFKEFGVINKNNIESITKFDTNVKFLSEEEIKRKSITEYIGIGDWTCIIDKLRLQLYYVPEGITINYIFNKLDSEWKIVESIIMEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGS5</accession>
    <name>A0A5C6ZGS5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Antitoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_15260</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Antitoxin component of a type II toxin-antitoxin (TA) system.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the phD/YefM antitoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006442">
        <property type="entry name" value="Antitoxin_Phd/YefM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036165">
        <property type="entry name" value="YefM-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02604">
        <property type="entry name" value="PhdYeFM_antitox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143120">
        <property type="entry name" value="SSF143120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="89" mass="10142" checksum="1B7DE60CE598CC13" modified="2019-11-13" version="1">MRSITVSTLRKNIKKHLKYVSSSIEIIVVPRGKADDAVVIMSISEYNSLKETEHLLSTRANSDRLMKSIEQLDDETLVRSNEDDVTLHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGT9</accession>
    <name>A0A5C6ZGT9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribonuclease H</fullName>
            <ecNumber evidence="2">3.1.26.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_08135</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="3">Binds 2 metal ions per subunit. Manganese or magnesium.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the RNase H family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.4" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.970.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009027">
        <property type="entry name" value="Ribosomal_L9/RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011320">
        <property type="entry name" value="RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037056">
        <property type="entry name" value="RNase_H1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017290">
        <property type="entry name" value="RNase_H_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002156">
        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01693">
        <property type="entry name" value="Cauli_VI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00075">
        <property type="entry name" value="RNase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037839">
        <property type="entry name" value="Ribonuclease_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55658">
        <property type="entry name" value="SSF55658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="2 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cauli_VI" evidence="5">
        <location>
            <begin position="5"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="domain" description="RNase H type-1" evidence="4">
        <location>
            <begin position="83"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR037839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR037839-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD89351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="211" mass="24064" checksum="7DCDECB615B67C9B" modified="2019-11-13" version="1">MAKKKYYTVWKGHKKGVFTSWNDCKAQTKDYEGAQYKSFATFDAAKEAFKGNYFDYIGKNKSFASELSAEQLKKIGKPNYNSIAVDAASSGNPGIMEYRGVDTKSKKQLFKQGPFAQGTNNLGEFLALVHGLGFLKKHDSDRIIYTDSRTAMSWVRKKYCNSKLERNATNKPVYDLVDRAVLWLKENDYKTTIVKWETKAWGEIPADFGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH63</accession>
    <name>A0A5C6ZH63_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">OmpA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_12365</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006664">
        <property type="entry name" value="OMP_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01021">
        <property type="entry name" value="OMPADOMAIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OmpA-like" evidence="3">
        <location>
            <begin position="509"/>
            <end position="627"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="627" mass="71613" checksum="D45074F438AD84F2" modified="2019-11-13" version="1">MKILNLYIGIIVFLFGNLCFSQSLKKANALYENRAYLDAAEIYEQLPKTAKTLEKLGDCYYFNAEIEKANKAYTEVYNKRDQDSLSEDFYFKYFDVLKSAKDYFTADQISVMYLNNPIHTENFKRLVKQINPYTYILNKLGNQGSVSNFGVGYFGNKIVFASTKNMESPEYNWNKKSYLDLYEATVSEGDDKQLDSIIAFSKNINIKDQHESSAVFTKDGKTMFFSRNQKKRVAIDSNKVAVVSIFKAQLENNEWQAIEPVSFSSDSYSTMHPALNSEEDKLYFSSDMPNSLGAFDIYYVDMAADGSFGTPVNLGAAINTAHREQFPFIAKDSTLYFASNGKQGLGGLDIFSSKYEENSYLEALNLGEIINSETDDFAFVVRDALDTGYMSSNRGGIDQIYSFERTPADRQYFVEGLVTDKRTGELLPNTVVTLFDNYGDIITEITVGEDGKYKLEVKPNQSYQLEGFQPKYIPETKYFDTNDRGNIEFNIELGIESYNDAEEIVNDREDGNTYIELENIYFDFAKWDIKPQAAKTLDILVNLLKKYPRMEIQLGAHTDSRSSFEFNMDLSEKRAAATLEYLVENGIPRKRLRSKGYGETKPLVNCGDDCTETEFSINRRCEFLILR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH90</accession>
    <name>A0A5C6ZH90_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 9">Acyl carrier protein</fullName>
            <shortName evidence="7">ACP</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">acpP</name>
        <name evidence="11" type="ORF">ESY86_08145</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 9">Carrier of the growing fatty acid chain in fatty acid biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7 9">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="7">4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.</text>
    </comment>
    <comment type="PTM">
        <text evidence="9">4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the acyl carrier protein (ACP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_007647141.1">
        <property type="nucleotide sequence ID" value="NZ_VORO01000007.1"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000036">
        <property type="term" value="F:acyl carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01217">
        <property type="entry name" value="Acyl_carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003231">
        <property type="entry name" value="Acyl_carrier"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006162">
        <property type="entry name" value="Ppantetheine_attach_site"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20863">
        <property type="entry name" value="PTHR20863"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00517">
        <property type="entry name" value="acyl_carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00012">
        <property type="entry name" value="PHOSPHOPANTETHEINE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4 7" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 7" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="1 7 8" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="3 7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="10">
        <location>
            <begin position="2"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="7 8">
        <location>
            <position position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD89353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="77" mass="8391" checksum="5704646486568C81" modified="2019-11-13" version="1">MSDIASRVKAIIVDKLGVDENEVVTEASFTNDLGADSLDTVELIMEFEKEFDIQIPDDQAENIATVGQAISYIEAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHB8</accession>
    <name>A0A5C6ZHB8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_10050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="60" mass="6410" checksum="EF55BFE12AEF5EF7" modified="2019-11-13" version="1">MKTLELNQMEMTVGGWDWQWDAPLTDSDWGCAALGLAAGIASGLNPLVGRLTTLGCMLTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHC1</accession>
    <name>A0A5C6ZHC1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_08315</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="160" mass="17903" checksum="12053805723E29F7" modified="2019-11-13" version="1">MKILFCFLVIFASAKECNQKKAEASAETKSEVLKTEAFQKDLTMTYEANTRGFYEKIWVEGDSVKFTNDRYGKVVVSNILPKNEKTTLVNLLNAVDLKTMPQLEAPSKAHQYDGAAMATLNITSEKSSYETKTFDHGNPPEAIKALVEKLLALKAKMVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHG8</accession>
    <name>A0A5C6ZHG8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Gliding motility protein RemB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_14485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038636">
        <property type="entry name" value="Wzi_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022690324" evidence="1">
        <location>
            <begin position="19"/>
            <end position="705"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="705" mass="81074" checksum="E8B080752306656E" modified="2019-11-13" version="1">MRYLLILCVILSYNVLSAQNTSDFEKAPIYPGCESQSIENLKLCLNNKINQFIFENFKLPQEVGADGYQGEVSVLFEVDAKGKIKLIYTDAVYETLKEETKRVFESLPKLVPGTYNGNPTFFQYGLDIKIPLVDPSEIRPDSLKKLETEKTSITDATLNEDLSQEYEDLKASIKPYEGLEYDSQLNIPFTHNYYARFDQEMNGLGTNSHTASKPYIYKDVAKYYDFEAEKKTMKKATDSWWGKKLWNEHLVQVQGENYWFTVDPILDLQVGKDTEAEFGSTFNNTRGIWVQAGLGKKFNFSTSIYESQGRFADYFNQYIESLKASNGEPVVPGRGVSKRFKEDAYDYPVAEAYITYSPVDFLNIQFGHGKNFIGDGYRSLLQSDATSPYPFVKINTSFWKIKYTNTWMSLRDVRPEVKEDGAFLTKYMANHYLSWNVSKRLNVGLFESVLWTDSNNRGVDLNYLNPVIFYRAIEFQTGQDAGNALLGASAKYKWNNKINLYGQFILDEFSLNDITGGKKSWKNKYGYQLGVKYFDAFKVDNLLLQMEYNRVRPYTYSHNSIVLNYAHNNQPMAHLWGANFSEAILIGRYNYERWYGDAKVIFGKRGFDFNTATDDFNYGGNVYSDERDRNANSGIEVAQGNQVNVFQADLQAGYIINPTTNLRLFTNITIRSFKPDAVTETLAKSSTTWFNIGLRTDVFNWYNDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHI7</accession>
    <name>A0A5C6ZHI7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Virulence RhuM family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_11520</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011204">
        <property type="entry name" value="Virulence_RhuM-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13310">
        <property type="entry name" value="Virulence_RhuM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015268">
        <property type="entry name" value="Virulence_RhuM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="327" mass="38007" checksum="E418F97A619FBDF3" modified="2019-11-13" version="1">MDSEIIFYQAEDGQTKIQTRLENETVWLTQEQMSVLFQRERSVITKHIGNVFKEGELEEKSNVQNLHISGSDRPVKYYNLEVIISVGYRVKSLQGTKFRIWATARLREYIVKGFTMNDELLKEAGGGNYFEELLARIRDIRSSEKVFWRKVLDVYATSIDYDANAGTSQLFFKTIQNKMHWAAHGQTAAEVIYNRIDAAKPFLGLTTFKGEQPTKQEVGIAKNYLNEEELNILNRMVTAYLEIAELQALNRKPMYMKDWIGRLDDFLKMTRNDILDNAGTISHKQALEKAEHSYQAYKDTLKNELSKVEQDFIKQLDNTHKQLKKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHK5</accession>
    <name>A0A5C6ZHK5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_08550</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015891">
        <property type="term" value="P:siderophore transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030148">
        <property type="entry name" value="Fiu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039423">
        <property type="entry name" value="TonB-dep_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32552">
        <property type="entry name" value="PTHR32552"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32552:SF68">
        <property type="entry name" value="PTHR32552:SF68"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0675">Receptor</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022739622" evidence="6">
        <location>
            <begin position="36"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="8">
        <location>
            <begin position="132"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="7">
        <location>
            <begin position="340"/>
            <end position="812"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD89423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="813" mass="91241" checksum="82F6D087DB91C7C7" modified="2019-11-13" version="1">MKILFKKPSLCLNWRPLKTAFIFTCFCFASFLSLAQQSHVVSGTVTMDNQPLPGVNVLIKGTRSGAQTGVDGQYKLELAQGDNILIFSFVGASSVEKSFYLDQDLVLNITLEEAPESLEEILLTAIRVDATSPITHSDVDKEDLAKRNLGQDLPVLLNYLPSVVTTSDAGAGVGYTGIRVRGINAQSTNVTINGIPYNDSESLGTFWVNLGDFASSVESLQLQRGVGTSTNGAGAFGASINVLTDNISEVAFAEISNSFGSFNTRKHTVKFGTGLLNEHFEISGRLSNIKSDGYIDRATSDLKSYFLQAAYKGDNTLIKAVVFGGNELTYQAYNGIDATQLAEDRRFNPSGQYTDEEGNTQFYDNEVDDYRQDHYQLHWNERYSKQWTSTVSLNYTQGSGFFEQYKEDEDFADYDLTPIEIGGETINTTDLIRRRWLDNDFYVLNANANYKDDNWNMSLGSSYSYYDGDHFGEIIWARFASNSETKDHYYDGNGTKTDFNTFAKATYRLNDKISLYGDLQLRVVDYETTGLTSDRIPFNVDERYNFFNPKAGITYKINRANDLYFSYARANREPNRDDFENNQTVKPEQLNDFELGWRHNTEQFRLYVNGYYMGYNEQLILTGQIDNVGNPIRTNSGDSYRMGLEVDAALAISNTFSIQPNFTLSSNKNISTFESVNGQVLDLGKTDISFSPELIAANAFVYQPKDGFQISLLSKYVGEQFMGNTENPDSKLDSYFVNDLNVTYEWIPKSIFKSVVFSALVNNIFNEKYVSNGYFGSFDFEDDTSSTGISTGYFTGFYPQATTNFLAGVTLKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHL6</accession>
    <name>A0A5C6ZHL6_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">UDP-N-acetylmuramate--L-alanine ligase</fullName>
            <ecNumber evidence="4 11">6.3.2.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">UDP-N-acetylmuramoyl-L-alanine synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">murC</name>
        <name evidence="16" type="ORF">ESY86_09395</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Cell wall formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + L-alanine + UDP-N-acetyl-alpha-D-muramate = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanine</text>
            <dbReference type="Rhea" id="RHEA:23372"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:70757"/>
            <dbReference type="ChEBI" id="CHEBI:83898"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the MurCDEF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.8" evidence="4 11"/>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008763">
        <property type="term" value="F:UDP-N-acetylmuramate-L-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00046">
        <property type="entry name" value="MurC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000713">
        <property type="entry name" value="Mur_ligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005758">
        <property type="entry name" value="UDP-N-AcMur_Ala_ligase_MurC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01225">
        <property type="entry name" value="Mur_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01082">
        <property type="entry name" value="murC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6 11" id="KW-0132">Cell division</keyword>
    <keyword evidence="7 11" id="KW-0133">Cell shape</keyword>
    <keyword evidence="10 11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="5 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 16" id="KW-0436">Ligase</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 11" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase" evidence="13">
        <location>
            <begin position="24"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_M" evidence="15">
        <location>
            <begin position="133"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="14">
        <location>
            <begin position="322"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="135"/>
            <end position="141"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="TXD89248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="466" mass="51651" checksum="6226C02D48D2ED6D" modified="2019-11-13" version="1">MKNSENKIDNNKQVLPLGEGWASHIYFIGIGGIGMSALARYFVAKDLKVAGYDKTNSDVITALVDLGVSVNFEDDISSVDTSFLNEENTLVVYTPAIPKHHKQFNYFKDEGFHLMKRSVVLGEITKQSFCLAVAGTHGKTTTTSILGHLLYQCGVEVTAFLGGISENYNSNFISSGTKVSVVEADEFDRSFLTLSPDFACITSMDADHLDIYGDASELQKSFVAFSEKVKPNGKLFIKNGLPIQGITYGIEDDSDYSVKNIKIENGSYLFDVKTPNALLKDFKFNLPGRHNLSNALIALAMSIEYGIPHQQLAGALLSYKGVKRRFSYQIKTDTLVYIDDYAHHPEEINAVHQAVREMYPGQKVLVIFQPHLYSRTRDFADEFAKSLSQFDDIALLEIYPARELPIEGVNSQYLLDKIDNENKSLIEKSQLIEVVKSSEASVILTLGAGDIGEEVKSIKTALSHAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHT9</accession>
    <name>A0A5C6ZHT9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4251 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10865</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025347">
        <property type="entry name" value="DUF4251"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14059">
        <property type="entry name" value="DUF4251"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022875845" evidence="1">
        <location>
            <begin position="25"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="183" mass="20475" checksum="4770190755987C5C" modified="2019-11-13" version="1">MKFIYCFVFIALSLFACGSSKSTATPAEIENLKKMVEQRAFEIESDYAYPVTTTALMSLQNAGLFLDGSNASSVSLIGNPNYLRVKGDSVFAELPYFGEVQMPSYPSRDNGIHFKTLLEDYEANQNEKSKAYDLKFGANGTDESYNVFITLFPNGRSSIRISGSKRNSIEYTGEVKKWSREKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHY6</accession>
    <name>A0A5C6ZHY6_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase</fullName>
            <shortName evidence="3">SEPHCHC synthase</shortName>
            <ecNumber evidence="3">2.2.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Menaquinone biosynthesis protein MenD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 7" type="primary">menD</name>
        <name evidence="7" type="ORF">ESY86_06145</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>2-oxoglutarate + H(+) + isochorismate = 5-enolpyruvoyl-6-hydroxy-2-succinyl-cyclohex-3-ene-1-carboxylate + CO2</text>
            <dbReference type="Rhea" id="RHEA:25593"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29780"/>
            <dbReference type="ChEBI" id="CHEBI:58818"/>
            <dbReference type="EC" id="2.2.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
        <text evidence="3">Binds 1 thiamine pyrophosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Quinol/quinone metabolism; 1,4-dihydroxy-2-naphthoate biosynthesis; 1,4-dihydroxy-2-naphthoate from chorismate: step 2/7.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Quinol/quinone metabolism; menaquinone biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TPP enzyme family. MenD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.9" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00079"/>
    <dbReference type="UniPathway" id="UPA01057">
        <property type="reaction ID" value="UER00164"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070204">
        <property type="term" value="F:2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01659">
        <property type="entry name" value="MenD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004433">
        <property type="entry name" value="MenaQ_synth_MenD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032264">
        <property type="entry name" value="MenD_middle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42916">
        <property type="entry name" value="PTHR42916"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16582">
        <property type="entry name" value="TPP_enzyme_M_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004983">
        <property type="entry name" value="MenD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00173">
        <property type="entry name" value="menD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 3" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0474">Menaquinone biosynthesis</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TPP_enzyme_N" evidence="5">
        <location>
            <begin position="9"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_M_2" evidence="6">
        <location>
            <begin position="230"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_C" evidence="4">
        <location>
            <begin position="424"/>
            <end position="568"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD89785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="588" mass="67103" checksum="B9FCB14D56955D4F" modified="2019-11-13" version="1">MIHPKIPLAQTVVQLCKLKNIKHIVISPGSRNAPLTIGFTNDDFFTCYSIVDERSAAFFALGIAQQIHKPVVLICTSGSALLNYYPAVAEAFYSDIPLIVLSADRPKHLIGIGDGQTINQKNVFENHILYSADLKLDLKDENRLSEKEDLPIFKSLENRLERILGLQQGIQNDNEQDINEAFDLARLKKGPVHINIPFDEPLYETVEVLSVRPKVKTLDLKSPKIDDVEIKDCVDEWYAANRKIILVGVLPPNQIEQKWLNELANDDSVLVFTETTSNLHHPDFFPNIDKMIGDLTEADFKALRPDILLTFGGMVVSKKIKKFLRDYQPKHHWHVDMKSANDTFFCLDKHIVAAPNAFFSEFLPKITHTAKSNYLPYWLEIKKQRHKRHLDYIKQIPFSDFKVFAAILKSIPFKSILQLGNSSTVRYAQLFNLNKSLEVFCNRGTSGIDGSTSTAVGCAAATPTKQTTFITGDLSFFYDSNALWNNYIPKNFRIILVNNSGGGIFRILPGHKNTPNFDYFFETTHNLTAKHLCEMFKFEYHQARDQEQLNASLKTFYNKSKTPKLLEIFTPRTENDDILLDYFEFLNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI59</accession>
    <name>A0A5C6ZI59_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="129" mass="14445" checksum="EADA1598C8A429A1" modified="2019-11-13" version="1">MIIAIAKGVVIVFGVFIIFMGFIMLFYPNQARSTLRKAGSTNFINYTEITIRLIPAISLILYADFSKFPGAFKILGWIMVITSLILYAVPRKTHHGFSMKSADILKPICFQLISPFALLFGGLILYNAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI73</accession>
    <name>A0A5C6ZI73_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">LysE family translocator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_12690</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30086">
        <property type="entry name" value="PTHR30086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01810">
        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="121"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="191"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD88371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="224" mass="24816" checksum="E3E010ED94552538" modified="2019-11-13" version="1">MLKDILAAIPFGIILAFTIGPVFFVLLETGATKGFRSAIIFDLGVILADIVFIIVAFYSTNKLVEKLKDDPNFIILGGVILIAYGLITFVKTSKSYRSIVKEYYKVNIEKNALGKLFVKGFLLNFINIGVLIGWLGFIVIGSTVTESENGVIVFIITMLGVYFLTDLIKIAVAKRLRNRLTPKLIYKTKKIVSLVIMGFGILLLIQGLFPSGTERLQETIEQSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIA7</accession>
    <name>A0A5C6ZIA7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Aminotransferase class IV</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_06725</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="SSF56752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="283" mass="32049" checksum="ECB0AF475508863A" modified="2019-11-13" version="1">MINFNGKLVAETNVISLENRGYKYGDAIFETLKVVHGKIFFWEDHYFRLMASMRIMRMEIPMDFTMEFLEAEVLKTINTNGLAKSSARVRINVDRGEGGKYRPISKTISYTMVAEALPSSFYELSTAKPYLVDLYKDFYVAPGLLSTLKTNNKAINVLGSIYAEENDFDNCLLLNTNKNVVEALNGNIFLVKGEHIKTPPLEDGCLKGIMRKQIIEVIANSGDYMVEEASISPFELQKADELFITNVIVGIQPILTYRKKEFSTSLTADILKRLNTKLRLAQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIE6</accession>
    <name>A0A5C6ZIE6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Tyrosine-type recombinase/integrase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_09490</name>
        <name evidence="7" type="ORF">ESY86_09515</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="5">
        <location>
            <begin position="9"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="4">
        <location>
            <begin position="121"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD89264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD89269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="319" mass="37708" checksum="EB1ADBF49314D5D1" modified="2019-11-13" version="1">MKKLILKNESFQYIEKSFREWLDILGYAESTVYNLPNHIRELFYYLEQNNINNINQLDNQIIKDHYNNLKLRSNDRKGGALSNGSLNKQLQALYKFTEYLRQSGRMILPTLNIDWENDDTKHIEILTTEEIQQLYKATQHYPKNIKYTKPHYFFEAIALRDCAMLTVFYGCGLRRNEGYHLTVDDINFDKQILHVRKGKANKERLVPFNKTNSKYLQDYVYDGRINLIKDKRESAFFINERGKQLSSQSMSIRLKLLQQRTDDLQLQEKNVRLHVLRHSIATHLLSNGMPLENISRFLGHNSLESTQVYTHLVNQEDGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIH1</accession>
    <name>A0A5C6ZIH1_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">3-deoxy-8-phosphooctulonate synthase</fullName>
            <ecNumber evidence="6">2.5.1.55</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_10100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-arabinose 5-phosphate + H2O + phosphoenolpyruvate = 3-deoxy-alpha-D-manno-2-octulosonate-8-phosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14053"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57693"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:85985"/>
            <dbReference type="EC" id="2.5.1.55"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Bacterial outer membrane biogenesis; lipopolysaccharide biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Carbohydrate biosynthesis; 3-deoxy-D-manno-octulosonate biosynthesis; 3-deoxy-D-manno-octulosonate from D-ribulose 5-phosphate: step 2/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the KdsA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.55" evidence="6"/>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00030"/>
    <dbReference type="UniPathway" id="UPA00357">
        <property type="reaction ID" value="UER00474"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008676">
        <property type="term" value="F:3-deoxy-8-phosphooctulonate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009103">
        <property type="term" value="P:lipopolysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006218">
        <property type="entry name" value="DAHP1/KDSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006269">
        <property type="entry name" value="KDO8P_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21057">
        <property type="entry name" value="PTHR21057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00793">
        <property type="entry name" value="DAHP_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01362">
        <property type="entry name" value="KDO8P_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAHP_synth_1" evidence="7">
        <location>
            <begin position="13"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD89111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="272" mass="30040" checksum="3CBCD8A7A8C3C737" modified="2019-11-13" version="1">MTLSEVPKLKHTNSNNFFLLCGPCAIEGEDMALRIAEKVLKITNQLEIPYIFKGSFKKANRSRIDSFTGIGDEKALKILRKVSETFDIPTVTDIHEIGDAKMAAEYVDVLQIPAFLVRQTDLVVAAAETGKVVNLKKGQFMSPEAMKHAVQKVKDTGNHKAWITDRGTMFGYQDMIVDFRGIPTMRAYAPTILDVTHSLQQPNQSVGVTGGRPEMIETIARAGVVNNVDGLFIETHFDPANAKSDGANMLHLDNLERLLSNLVAIRKTVNSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZII4</accession>
    <name>A0A5C6ZII4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA-protecting protein DprA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">dprA</name>
        <name evidence="3" type="ORF">ESY86_07670</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DprA/Smf family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009294">
        <property type="term" value="P:DNA-mediated transformation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003488">
        <property type="entry name" value="DprA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041614">
        <property type="entry name" value="DprA_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43022">
        <property type="entry name" value="PTHR43022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02481">
        <property type="entry name" value="DNA_processg_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17782">
        <property type="entry name" value="DprA_WH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00732">
        <property type="entry name" value="dprA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DprA_WH" evidence="2">
        <location>
            <begin position="309"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="367" mass="41069" checksum="BF6B8EC24486D35C" modified="2019-11-13" version="1">MTERELLYTLALQHVPKIGDVTAKKLISHCGSAEGVLTERKNNLLKIDGIGSTILQNLFDRKHLKDAEQELQFIKENDIKCLYFTAPDYPERLKQCIDSPILIFQAGKVNLNNKRIISIVGTRKITTSGVAFCEKLIEQLAIFDPIIVSGFAYGTDITAHKAAIKHKLQTIGCLAHGLDQIYPKTHKKYMVEVEKHGGFLTDFWSSDAFDRNNFLKRNRIIAGMSEATIVIESAEKGGSLVTADIANSYDRDVFAVPGRVTDSQSTGCINLIKTQQAHLLSDPMDVPYILNWQLENAQKPAIQKQLFVELNPDETRIYNFLKDNEKQLLDVIAIACELPTFKVAGLLLTMELKGIARPLPGKLFELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIR6</accession>
    <name>A0A5C6ZIR6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="10">3-dehydroquinate synthase</fullName>
            <ecNumber evidence="10">4.2.3.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">aroB</name>
        <name evidence="10" type="ORF">ESY86_06085</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.4" evidence="10"/>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003856">
        <property type="term" value="F:3-dehydroquinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016037">
        <property type="entry name" value="DHQ_synth_AroB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030963">
        <property type="entry name" value="DHQ_synth_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030960">
        <property type="entry name" value="DHQS/DOIS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01761">
        <property type="entry name" value="DHQ_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001455">
        <property type="entry name" value="DHQ_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01357">
        <property type="entry name" value="aroB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0170">Cobalt</keyword>
    <keyword evidence="7 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="DHQ_synthase" evidence="9">
        <location>
            <begin position="62"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD89773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="361" mass="40089" checksum="2FF1B7B87A1A1906" modified="2019-11-13" version="1">MNSIETKDYTVHFNSVAYEAISSYLKQNNFSKIFVLVDQNTHEHCLSHFLSHLETDLEIEIIEIEAGEAHKTIDTCVGVWESLSSLGADRKSILLNLGGGVVTDLGGFVACTFKRGIKYINIPTSLLAMVDASVGGKTGVDLGSIKNQVGVISSGDLVLIDTSFLDTLPQNQLKSGLAEMLKHGLIADRSYFESLTNLSQLTLNDLDQLIYDSVLIKNDIVTKDPLEHGIRKHLNFGHTLGHAIESYFLEHLEKKALLHGEAIVIGMILETFISGKLLGFPENDLDYITRSFNKIYPPVSIDVTDYGKIIDLLKFDKKNEHGNINFVLLEAIGKPKIDCLVDNELILESFEFYKNSSRLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIS2</accession>
    <name>A0A5C6ZIS2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Efflux RND transporter permease subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="351"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="376"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="402"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="453"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="482"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="547"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="908"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="934"/>
            <end position="954"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="960"/>
            <end position="981"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1002"/>
            <end position="1025"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1031"/>
            <end position="1058"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1064" mass="118480" checksum="6F76C7437CA64B4A" modified="2019-11-13" version="1">MKEGIAGKIAKIFIQSKLTVLLMIVFMVVGVYSSFLIPREEEPQIDVPMADIFVGYPGASPTEVESRVVKPLEQLISNIKGVEYVYSTSMKEQGMVIVQFYVDEDIERSFVKLYNEISKHMGQMPEGVTFPLVKTRAIDDVPMLGLTLWSENYDDYQLSQMAQELEAEIKKINDVATTHKIGGRNRQLRVVLDKDKLAASGLDFLSVSEMIKGNNAQLSSGSFDKNDTEFLVTTGTFLESATDVENLVVGVQQNRPIYLKQVATIIDGPEVPKNYVSLGFGKGSEKASEFKSEYPAVTISVAKRKGADAMKISEVIIDKVEHLRSTLIPDDVHVEITRNYGETASDKVSELLWHLIGSIFAVTLVVMLAMGWRGGLVVFLSVPITFALTLLSYYMMDYTLNRITLFALVFVTGIVVDDSIIIAENMHRHFKMKRLPFKQAALYAINEVGNPTILATFTVIASVLPMAFVSGLMGPYMAPMPIGASIAMILSLFVALTITPYLGYIFLREKEKKGQPEKVEKPLEDTFIYKIYNKLERPLLESSAKRWLFLGGTFAILLATMVLFFTKSVAVKMLPFDNKNEFQIVIDMPEGTTLERTGVVTQEISQYLSTRPEVVNYQNYVGTSAPITFNGLVRHYDLRGGSYMADIQVNLIAKGKRSAQSHDIVKLLRPDIQKIASKYNANVKLVEVPPGPPVLSTIVAEVYGPDYKEQIKIANSIQTILKNTDDVVDIDWMVEDDQTEYQFDINKEKAMLYGVAPQQIAHTMNMALSNRPITTLYDEDASNQVGLVLTLDEKEKSTITDISQLKVSSTQGTMVPIADLVDIKETIAAKSIYHKNQKRVVYVLADMAGDLESPAYAILGMEEKLKEIPLPQGYTLNEMYLGQPEYEDDYTVKWDGEWQITLEVFRDLGIAFLGAIILIYILIVGWFQNFKAPIVMMVAIPLSLIGIILGHWIMDAFFTATSFIGMIALAGIMVRNSVLLIDFINLRLDEGIPIKQAVVEAGAVRTTPILLTAGTVVIGAFVILFDPIFQGLAISLMGGTIVSTVLTLLVVPLVYYMIEKKNYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIX6</accession>
    <name>A0A5C6ZIX6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GTP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_08925</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SIMIBI class G3E GTPase family. CobW subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011629">
        <property type="entry name" value="Cbl_biosynth_CobW-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036627">
        <property type="entry name" value="CobW-likC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07683">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00833">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CobW C-terminal" evidence="2">
        <location>
            <begin position="256"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="405" mass="46045" checksum="A7A5206147B2C69B" modified="2019-11-13" version="1">MKKLPVTVLSGFLGAGKTTLLNHILHNKEGLKVAVIVNDMSEVNIDAQLVQNENTLSRTEERLVEMSNGCICCTLREDLMIEVEKLAKENRFDYLLIESTGISEPIPVAQTFSFESEDGSIDLSRFSYIDTMVTVVDGFNFLKDFSSPDYLTSRNLTDIENDTRTIVNLLTDQVEFANVIVLNKTDLITEVKLKQLYGILQKLNPKARIVPAINSQIPLTEIIGTNLFNFEEAENSAGWIQELENEHIPETEEYGIGSMVFRSKKPFHPERFWDFATAGFPGNILRSKGLFWLSSRPDQALIWSSAGGSLKTDPAGVWWASMPFSERINNEAFVDNQGSIESDWHPEFGDRKNELVFIAQNLDREKLTGLLEQCLLTEAEQNLWKKHKLQLTDHWPIETLEYTKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ42</accession>
    <name>A0A5C6ZJ42_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Helix-turn-helix transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_07270</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="2">
        <location>
            <begin position="185"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="290" mass="33153" checksum="4067FE0A37FC141E" modified="2019-11-13" version="1">MHRKPTLEKISPEFGSSVFVKKSTSASADSKAFWHFHPEIELVFIDKGSGKRHIGNHLSYFNNSQLLLLGSNLPHNGFKDRLTQQGSEVLVQFNPDFLGAYFFDVPEMASINILFERAKNGILFKPKTKKRVGKKIQKLNELKGFDRILLLIKILHLLAEAEDYEILNAEGFVFETEKQDSSKIDIIYKYVNTHFKQHITLDEIAEAVSMTVPAFCRYFKKSTGKTFTKLVNEYRVVHATKLLSESEMSIADVAFECGFNNFSHFNKLFKEMTGKSASKYRKGLTNLYAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ93</accession>
    <name>A0A5C6ZJ93_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06495</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022741878" evidence="1">
        <location>
            <begin position="19"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="111" mass="12494" checksum="C997D3CE0B8AA4FA" modified="2019-11-13" version="1">MKPFYVLLLIFCPFSLMAQSITGIIYDAETTIKGVKIFNDTQNKVDFSDARGNFKIEASVGDQLSVISLFHEPLVVTVQSSFFDAPVVFELKKVTNELDEVQLMNVVEKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJF6</accession>
    <name>A0A5C6ZJF6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Pseudaminic acid cytidylyltransferase</fullName>
            <ecNumber evidence="1">2.7.7.81</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pseF</name>
        <name evidence="1" type="ORF">ESY86_07925</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.81" evidence="1"/>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003329">
        <property type="entry name" value="Cytidylyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020039">
        <property type="entry name" value="PseF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02348">
        <property type="entry name" value="CTP_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03584">
        <property type="entry name" value="PseF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="229" mass="25824" checksum="1B394F5DA97BA699" modified="2019-11-13" version="1">MANLAIIPARGGSKRIPRKNIKAFLGKPIIAYSIEAALNSDLFDEVMVSTDDEAIANIATHFGASVPFLRSDHNANDHAVLADVIVEVIAEYLKIGKTFNTICCILPTAPLLTAQALLEAHEKLMKFDFDSVFPVLEFSFPIQRALKIEHNKISMVWEEHLNTRSQDLESRYHDAGQFYWLKSDAFKSNKKLFTQNSGAIIISELEAQDIDTETDWRLAEIKFKLQQND</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJN7</accession>
    <name>A0A5C6ZJN7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">SMI1/KNR4 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_09530</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037883">
        <property type="entry name" value="Knr4/Smi1-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160631">
        <property type="entry name" value="SSF160631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="150" mass="17312" checksum="5E80427987895715" modified="2019-11-13" version="1">MSIIRVLKIIENNIEESDFVGKIKVDIVKKTENILGLKFPKSYRMFIENYGCGDIFGIEIFGIISDPITDVQTIPNVLWITNEFKNKGLPKGYIIISETGDDGSYYTINTNIKNDCDENPIYLWNSFNLKESKVYDSFGDFLYDFLKEHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJQ8</accession>
    <name>A0A5C6ZJQ8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06185</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="169" mass="19395" checksum="CA83029C8A92764C" modified="2019-11-13" version="1">MKKVFLLLMATVMLSVSCEDNSKKKDLAEQRNSLMVENDSINAHQDKIMAAHKEMMAAHQMFSEKLKGMEVKDSSMLEVIAKHDVMLKRHEAEAKGNETMLAGHKELTSDFDQMSEAEMETQITQMKEDHNKVKSSQSEIMDQQQTMMDDHQKLKDNMANEMNKDKVKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJV3</accession>
    <name>A0A5C6ZJV3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_04210</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007492">
        <property type="entry name" value="LytTR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04397">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00850">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50930">
        <property type="entry name" value="HTH_LYTTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="2"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="HTH LytTR-type" evidence="3">
        <location>
            <begin position="145"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD90578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="251" mass="29257" checksum="15BC1DB501C8ABD9" modified="2019-11-13" version="1">MKVIIIEDEKPSARRLQRMLAVLEIEAETMLHSVEESINWFQNNAHPDLILLDIQLSDGLSFEIFEAVEIHSAVIFTTAYDAYALQAFKLNSIDYLLKPIDDGDLEKALSKFKGRSSKQQAVTLDFDDIKKLLVNPLEREYKKRFSVKVGQHLKLINIDDIECFYSENKGTYAFTSEGRNYLLDTTLEQLEAELEPQKFFRISRKFFVNINAIKDMISYTNSRLQIKLNNFKEQEVVVARERVKDFKDWLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJY1</accession>
    <name>A0A5C6ZJY1_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Methanethiol S-methyltransferase</fullName>
            <ecNumber evidence="5">2.1.1.334</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">ESY86_10730</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the methylation of methanethiol (MeSH) to yield dimethylsulphide (DMS).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>methanethiol + S-adenosyl-L-methionine = dimethyl sulfide + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:50428"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16007"/>
            <dbReference type="ChEBI" id="CHEBI:17437"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="2.1.1.334"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the nurim family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.334" evidence="5"/>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009915">
        <property type="entry name" value="NnrU_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033580">
        <property type="entry name" value="Nurim-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31040">
        <property type="entry name" value="PTHR31040"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07298">
        <property type="entry name" value="NnrU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="88"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="118"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="NnrU" evidence="10">
        <location>
            <begin position="55"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD88959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="245" mass="27928" checksum="F4BDE220643E254F" modified="2019-11-13" version="1">MKKFIVLIYGLIAYLVFLISFLYAIAFVGDFLVPKTINSETESTGLSAIIINLSLLSIFAIQHSVMARPAFKAWWIKIIGKAAERSTYILLTSLALLLIFWKWQPINTVVWEVGNSTLAMLIFGISALGWLIVLLSTFMISHFELFGLTQIFDNFKSRTSKSATFQTNFLYKIVRHPIMLGFIIAFWFTPVMTLGHLLFASVTSLYILIAVKYLEEKDLRKTLGKAYEDYQQKVPMILPFSKIAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJY4</accession>
    <name>A0A5C6ZJY4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidoglycan glycosyltransferase</fullName>
            <ecNumber evidence="1">2.4.1.129</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">ESY86_07595</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>[GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate = [GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23708"/>
            <dbReference type="Rhea" id="RHEA-COMP:9602"/>
            <dbReference type="Rhea" id="RHEA-COMP:9603"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58405"/>
            <dbReference type="ChEBI" id="CHEBI:60033"/>
            <dbReference type="ChEBI" id="CHEBI:78435"/>
            <dbReference type="EC" id="2.4.1.129"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.129" evidence="1"/>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008955">
        <property type="term" value="F:peptidoglycan glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3810.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001264">
        <property type="entry name" value="Glyco_trans_51"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036950">
        <property type="entry name" value="PBP_transglycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00912">
        <property type="entry name" value="Transgly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="26"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="domain" description="Transgly" evidence="10">
        <location>
            <begin position="75"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="9">
        <location>
            <begin position="442"/>
            <end position="698"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD89641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="785" mass="88988" checksum="AEF4230C685A36FE" modified="2019-11-13" version="1">MAKKTVAKKKNTNKETSDFAKYIRSFWLLFAGAILAFFSMFLLASWGLLGEMPDYTILENPKTFLATEIISSDNKTLGKFYLDDNRTPVDYNELPKNLVEALVATEDIRYYEHSGIDFRGTLRAVVKLGAGGGASTISQQLAKQLFTKQVSSNKFQRLFQKVREWVIAIRLERQYTKEEIIAMYFNIYDFGNNADGIRSASRIYFGKEPIELDLKEAAMLVGMFKNSSLYNPIPSRNPEGTKNRRNVVLNQMEKYEYINQKTEDSLRSTGLDLQFSPESHREGSATYFRAFLDKFMKDWIRENPKPNGEKYNLYNDGLKIYTTIDSRMQMHAEDAVTRHMPRLQAEFFKQNTPDRNKTAPFLELNASEIEDLMNRSMQRSERWRIMKVQGKTNEEIRESFEVPTQMSVFAWVDGKASEIDTIMKPIDSMRYYKSFLQPGMMSMDPLTGHVKAWVGGMNYRHFQYDHVNQGKRQVGSTFKPFVYATAIDQLHLSPCDTIPRQQITIEADKFGNPLPWTAKNSDGKYGGFVTLKYALAHSINTVTARLMDKVGPQPVADMARNLGVESNIPAVPAIALGTPDISVYEMVAAYSTFANKGVYNKPVMVTRIEDKNGTVLYQFVPETRDVLSDEVAYTTVKLMEGVVESGSGARLQRSWDPDSGIYKEIMTGYPYELKNPIAGKTGTTQNQSDGWFMGMVPNLVTGVWVGAEDRAAHFKSITYGQGASMALPIWGLYMKACYADEELNISQEPFERPENLSIEVDCSKVPTGTEEVVDPSDELEGVLDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJZ0</accession>
    <name>A0A5C6ZJZ0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Amidohydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_05950</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032465">
        <property type="entry name" value="ACMSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21240">
        <property type="entry name" value="PTHR21240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04909">
        <property type="entry name" value="Amidohydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="3">
        <location>
            <begin position="100"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD90276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="378" mass="43849" checksum="CB773071670635AC" modified="2019-11-13" version="1">MSTADKNANTSEAPNNTRRKLRINGHSHLLPYPEEIPQYMKDKGIFWVDKDRKFMLQKDWSRPVTDSSFFLDEKLSWMERFKIDHAVVLNLSQLYGNGLRVEEMKQALRFQNDYNAKIQRENPSKFTCGFVVHPGFVRGACWEIERCVEELGLRLLCLPTHYMDTIGTWRCIFDEENEPIFELANKYNLAVEIHPYDGEKFIKLENTAWRFHLIWMLAQCADAYHFLTLNGYQDKFPNMRTCFAHGGQLAQINLGRRIQGFDGRPDLFEGKNHPRKAVGHKNIFFDTLVHDTGGLELLIKNQGSKQVLMGLDDPYPLGEMESTQQSSYPGKILDLAVKRDIIDEKQRDAIWEDNVIQWLCGDDQAAKDKLIARILSKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK62</accession>
    <name>A0A5C6ZK62_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Ribonuclease HII</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_01735</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="811" mass="91572" checksum="EB533A2DC1B29ABA" modified="2019-11-13" version="1">MRTYWLPLLCLLLLFSCKDDRSSNATLLSKIPENAEIVLKANNLDGFKSVIQNNQLLKELKTLATFQDLEQQLKPLEYINTANPVYIALAKDDNDSLEISVITKYDPQIIQFDSVPNIMVERFESKDESVQKISLNNTIYYSAYKDSILFLSNRLYLVEQSFDTKPIASELQRIYETSNSEKSVSVLINHKRFVQNLFISTNAHFNAQQFTNYSLLDADISQNDIIINGITTARDSSKSLINIFKGSIPQEHLMPTVLPSSTQGFSSFTTDQIKKLKTNLQLFKNTDSIVEMDRLFDNVIEFGQAEIENTSVFLMRSIDPSITIEELASQDVSSSYRTVDIYSHNAPEALFSTFSPLVPNLRTSYFINLDDFFIFAESSATLENIIADYQNGNILAEDEPYKDMMKHLSDESSLLFYGNSKKLQAILEENIAGATDLNLDAYKTAAIQYIYDSDFAHVNAILETHKSRGASKSVSETVNVTIDANLSAAPQLAKNHTNNQMDVAIQDINNNLYLISNTGKVFWKKQLSGKILGKIEQIDMYKNGRLQLAFATANRVYVLDRDGKDVAPFPLKFNDEITQPLSVFDYDNKRNYRLVVTQNKALLMYDQLGQAVTGFNFSPANNSISSQPKHFRVGRKDYIVFTEGDHLEILDRVGKPRIKVKEKISFSGNEVYLYNDHFTTTNTSGELLEVNQNGRVKHENLNLNANHKIATTSKTLAAISDNNLTIKSKTIALDFGNYTEPSIFYIDDKIYVSITDLQAKKVYLFDSQAKPTANFPIYGNSKIELANMDGDSNLEVLTKGSDNSVIIYKIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK78</accession>
    <name>A0A5C6ZK78_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">LysE family translocator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_06635</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30086">
        <property type="entry name" value="PTHR30086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01810">
        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006324">
        <property type="entry name" value="LeuE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="30"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="103"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="140"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="177"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD89962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="199" mass="21550" checksum="0D1CD5BA0FBC0443" modified="2019-11-13" version="1">MLATSALAISPGPDNIYVLMQSLVNGKKSGLATVAGLISGCLVHTSLVAFGVSALIKANDTLFFLLKLFGAVYLLYLAYQVYKSDAALDLGSNQIKKKSLSQLFKQGVIMNVLNPKVSIFFLAFFPGFLFSDTMGTVAQFYILGLLFMLVSLIIFSSIALLAGSISSYIKGHKRIGLYLKWLQIVVFVGIAVLIFTSEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK80</accession>
    <name>A0A5C6ZK80_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="146"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="167" mass="18984" checksum="540E5846F26E31BC" modified="2019-11-13" version="1">MNGFLLFAIAMCVFAVVAFLSHYFSAKKVILRTLAKLPDLPVASLKSNSFSKITGKALHVKDPLIVPYSKRKCIFYDIKIEQKKSSGKSSYWKTLVHETKFEAFFVQRHAHYVVVNPEEHPRNYISYLNVDKNRILAPSTTQRQHLSPSCISTKSKPKIFSDSSTSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKA5</accession>
    <name>A0A5C6ZKA5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ferrous iron transport protein B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">feoB</name>
        <name evidence="11" type="ORF">ESY86_07350</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Probable transporter of a GTP-driven Fe(2+) uptake system.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell inner membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015093">
        <property type="term" value="F:ferrous iron transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055072">
        <property type="term" value="P:iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01879">
        <property type="entry name" value="FeoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003373">
        <property type="entry name" value="Fe2_transport_prot-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011640">
        <property type="entry name" value="Fe2_transport_prot_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030389">
        <property type="entry name" value="G_FEOB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011642">
        <property type="entry name" value="Gate_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07664">
        <property type="entry name" value="FeoB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02421">
        <property type="entry name" value="FeoB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07670">
        <property type="entry name" value="Gate"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00437">
        <property type="entry name" value="feoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51711">
        <property type="entry name" value="G_FEOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0410">Iron transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="279"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="339"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="413"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="454"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="509"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="643"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="678"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="domain" description="FeoB-type G" evidence="10">
        <location>
            <begin position="4"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD89595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="699" mass="78027" checksum="31489865D99B3484" modified="2019-11-13" version="1">MSKQINVALIGNPNTGKTSVFNALTGLNQKVGNYPGITVEKKQGLCKLPRGVKAHIIDLPGTYSLNASSLDENVVIELLLNKNDKDFPDVAVVVSDVENLKRNLLLFTQIKDLEIPTILVINMSDRMRKKGILLDIPLLEKELNTKIALVSTRKREGIDNLKQLIADYRKLSTEPCLKASEIDSVYFDSLKEAFPNQLLYKLWLVITQDVNFGKTDRNEIETINSFKTKSKADLKRLQQKETIKRYQFINNTLKKGQTVDLASATDLRIKLDRILTHKVWGYLIFGVILLTIFQAIYDWAQVPMDLIDRLFVFLSEWTKSALPSGVFTSLLAEGIIPGLGGIVIFIPQIAFLFLFISLLEESGYMSRVVFLMDRIMRRFGLSGKSVVPLISGTACAIPAIMATRNIESWKERLITILVTPFTTCSARLPVYLIIIELVIPEGRFLGLGYQPLTLMLLYIIGFATALVSAWMLDRILKIKKKTFFVVEMPNYKLPLFKNVAITVIEKTKAFVFGAGKIILAISIILWFLASYGPGDDFNNAAEIVSAQSSSKDFSSEELREEIASYKLEHSYIGIAGHAIEPAIRPLGYDWKIGIAIVSSFAAREVFVGTLATIYSVGSGDQETIKSRMAGEVNPILGGPLFNFASGISLLLFYAFAMQCASTLAIVKKETNTWKWPMLQLFIMSGFAYVVALVAYQLLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKB1</accession>
    <name>A0A5C6ZKB1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF3667 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022134">
        <property type="entry name" value="DUF3667"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12412">
        <property type="entry name" value="DUF3667"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="236"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="267"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="295"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="327"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="353" mass="41075" checksum="28387DE85DFDCC9B" modified="2019-11-13" version="1">MDQDLQQCQNCDYQLKADFEFCPNCGQKVNEKLTLKVLFYNTVSNYFSVDARFLKSFLPLVFKPGFLPTKFIEGKRSRYLHPAQLYLFISVVFFFILSLSTNSQPEKINQELLRTKSSEKASVLQDSIEAKQLDSVDRAEAKAFLKNNKWLGSVPEQKIDSILADPNVNKNDISFGFDELKLDSLIAANASDKEIFKAMEMNDDAGWLKRKFYGQILKFYKSRDGGSILKVIYDKIPIALFFLLPLFALLLKLFYSKKGNYTHHLVFSFYYFSFLFLIFSIIFGINLIWNVSGWLDFLLLFSAFVYFLIALKRFYHQGWFVSFFKANVISFLFLVFILPATATILFVYAFLFY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKL5</accession>
    <name>A0A5C6ZKL5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amidohydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_04040</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023110068" evidence="1">
        <location>
            <begin position="22"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydro-rel" evidence="2">
        <location>
            <begin position="76"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="433" mass="47363" checksum="7A60319C245563E9" modified="2019-11-13" version="1">MLKNSLLLLALFLLCFGNSNAQSNATYIIAGTFYDSQNNTLLKDQVLHIEDSEIKALLKRQDIPNNAHIIDLSSYTVLPGLIDAHTHVLFSQDANEDFAESSINTLTLVSEALRTLRGAKRAKSYLDVGFTSIKDLGNSGQFLDVALRDAIDEGSIIGPRVYASGPILSSVGGQIYGVSHKHQHLVGLEYRVITSVDDARNSVREHINQNVDLIKICADNIPNNTRLNSAEITAIVETAHQYGLKVTAHSISNQSAWEAIQAGVDGIEHGFFLEDSTLTAMATKNVFLVPTENSRNYMNTYSDLAGYTSEERDFIDGYLNRSKDRLKRAIEKGVTIVAGSDNYTDIKTTRGASSKDLFRAYFEAGMAPLDILQSATFVSAQAMNQDHVIGVLKTGAKADIIAVKGDLINDFVSSINTIVFVMKDGQIHLNTVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKS8</accession>
    <name>A0A5C6ZKS8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase" evidence="1">
        <location>
            <begin position="48"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="477" mass="55575" checksum="FEA0825B6130DCC8" modified="2019-11-13" version="1">MKKTLLALIILSVITACEQQKEKKYNEFEIVENTKTKRLDSLFIEFRKYEEFSGNVLVAENGKIVFQNSYGLANEETNQKLNTETVFELASVSKQFTAMGIVQLHKDGKLSYNDLIDKYIPELKNYKGITIKNLLTHTSGLPDYMSVADKKWNKSQIATNDDIISLFQEFEPEQEFEPGQDYAYSNTGYLILGTIIERVSGKSFEEYLNEKIFKPLEMKETLVYRRRYEPKEVSNYAQGYIYSDSLNRRILPDENGKENFYIYLDGIVGDGMVNSNLHDLLKWDRALYTNYLINEQDKNLIFSPNKYSDSLETNYGFGWYIKKDTTYGKIVSHGGSWAGYSTYIERHLVNDKTIIILQNHGTRKIKMPYKQIQNILYDLPVDKTVRLEDKTLKRYTGIYKEENGKDVELIFREKSLWVPISATTKFPLIPISETKFRLYGFRPEVIYEFILNDKGAVESYRVILKETGVERTAKIKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKV6</accession>
    <name>A0A5C6ZKV6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MCE family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_03650</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003399">
        <property type="entry name" value="Mce/MlaD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02470">
        <property type="entry name" value="MlaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="MlaD" evidence="2">
        <location>
            <begin position="41"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="330" mass="35984" checksum="F684325462FC2EBC" modified="2019-11-13" version="1">MGKSNAQKIKVGIFVVVGTVLLIAALYFIGSRQQMFSKNIQLFAVFENVNGLQLGNNVRYSGVNVGTVSSIEMVEKGKIIVEMSVEEKTAFFIKKDAIASISSDGLVGSMVVNILPGKDEKAGQVVSGDTIKNHSKVSTDEMLSTLNKTNENAALLTADLLKITNQIVSGKGSLGALVNDSLMAKDIRQSAEELKKMTSGATQAIAQINSIISKINYDESAAALLLSDTVSKNQIQNVIGNLEKSSDHINEVTKSLDVYIKEIKSGKGVLNHITQDEVLVKNIDSTVISIKEASEKLNENMEALKHNFLFRGYFRKQERLKRKQAEAMKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKW3</accession>
    <name>A0A5C6ZKW3_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">TSPc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_09625</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00245">
        <property type="entry name" value="TSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TSPc" evidence="1">
        <location>
            <begin position="322"/>
            <end position="587"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="609" mass="69586" checksum="79E771ACCCDED9A2" modified="2019-11-13" version="1">MRTCFILTILCCTSIIVSGQKLELKKASPFTAVKWEGEQPIVKFENEWYHFEKLDHFSKKEILDFCKIEYGDNWQKRFSEDLVSVLKGLGYQPNLKVSLQLSKNDISQTRTGTFTFENRQLSLHYNKAVKASKFPQKLSIAEALADLRQFEEILKTRSSYAQLSTFDYKTAIRELGTSIVIKKNEVDINEFTNDLGKIMAQIGDRHSSIKNESFNSIGHNTYNLRLPFGIAPIDGKIVATKENSKIRNYTYFYDSHPNIKSINAIDIETLLNSYNYRDKKAPREAKLSRGSRAIQKYGALLYKNNIQCPDSVIVIFTNEATEKTKTFQLTTDKKGYYSQLIQEHSNFREKVGNGNFNSLSNILDSNIGYINIPEMYHYEDLEGLEDYIENTLRSFLDTKALIIDIRNNPGGSRDILKTFARYIVQPEQSPWIANVAYLRADSTIFGDDESMSGRYLYSYNSEELSDNDRNAIDQFDTDFELQKAFDDSKFSNPFYMVLHNGKQQYRHPVYILVNENSFSAATVFTSAFKSLPNVRIVGETTDGSSGNSIKINLKNSNIRVKISTMLSFQRNGKTLDGNGTVPDINIPADKIQVLDGYDNQLSKLIENIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL22</accession>
    <name>A0A5C6ZL22_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TetR/AcrR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_03055</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032551">
        <property type="entry name" value="BscR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16295">
        <property type="entry name" value="TetR_C_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="8"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="192" mass="22103" checksum="4BC36A16DA360A46" modified="2019-11-13" version="1">MSKVEKSQIKREALVRATINLVNSHGFHAAPMSKIAKLAAVSPGTIYLYFENKQDLVDKVYLDVKTAFSEFAFKDYDEKVSVEKGFEKIWKNIAVFKLREVEKAMFLSQCDNTPIIDDSSRQEGLKHLQPLLNLWELGKKEGLIKPVSPYMLYAFSIYPVAFLMNMQQQGLYKLTPEHIDEAYKMAWNSIKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL45</accession>
    <name>A0A5C6ZL45_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Putative DNA modification/repair radical SAM protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_00260</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023874">
        <property type="entry name" value="DNA_rSAM_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21180:SF9">
        <property type="entry name" value="PTHR21180:SF9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01102">
        <property type="entry name" value="Uncharacterised_Radical_SAM_Su"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03916">
        <property type="entry name" value="rSAM_link_UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD91068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="420" mass="48125" checksum="560A4E6CD03589C8" modified="2019-11-13" version="1">MSFQRTQEKLKILADAAKYDVSCSSSGSKRNNTNKGLGDASGMGICHSYTEDGRCVSLLKILLTNHCIFDCAYCVTRKSNDIKRAAFKVQEVVDLTISFYRRNYIEGLFLSSGIFKDANYTMERLVAVAKKLRLEENFNGYIHLKSIPGASDELMHEAGLYADRLSVNIEIPTEEGLKRLAPDKKREDFIKPMLKVKNDIVQYQAEKKVIRNTPKFAPAGQSTQMIIGASGENDFQIMQTSNLFYKTYNLKRVYYSGYIPISYDARLPQIGTAVPMMRENRLYQTDWLMRFYGFDVSEILNETHQNLDLDIDPKLGWALRNLHEFPVDVNTADKRMLARIPGLGMKSVYKILNARRFRRLNWEHLKKIGIALNRAQYFVVCDSNQFERRDLSSKKIKGLILQNSTSKYAKTLSNQLSLFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL51</accession>
    <name>A0A5C6ZL51_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Efflux RND transporter periplasmic adaptor subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_05045</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022813296" evidence="3">
        <location>
            <begin position="23"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="4">
        <location>
            <begin position="60"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="133"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="376" mass="40489" checksum="C0C81B101B12A5B9" modified="2019-11-13" version="1">MKKYTYLLIVITASLFMASCGSEENNVAADKRPAVKVQVSEVSGSNTNPFLSVSGKIQSVNNADLSTRMMGFVKKAPFNVGDKVSKGQLLVSINNAELQAKSAQVNAGITEATVAFNNAQKDYKRFKNLFEDNSASQKELDDMTARYEMAKARLESAKQMKNEVNAQYAYTNITAPFSGVVTAKSVEEGDMANPGQALISIESPGNFEVMAMVPETEISQIKQGAEVDVLVKSINKTLKGNVSEISTSSKNTGGQYLVKIALDKTDVNILSGMFASVQFPVEKKAATEMVLIPTAAIINNGQLSGVYTVSESNTALLRWLRLGRTFDNQVEVLSGLSADETYIVSADGKLYNGVKIIPSPALPEGKGVNSETNYNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL76</accession>
    <name>A0A5C6ZL76_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Superoxide dismutase</fullName>
            <ecNumber evidence="2 6">1.15.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ESY86_05205</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2 H(+) + 2 superoxide = H2O2 + O2</text>
            <dbReference type="Rhea" id="RHEA:20696"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:18421"/>
            <dbReference type="EC" id="1.15.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the iron/manganese superoxide dismutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.15.1.1" evidence="2 6"/>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004784">
        <property type="term" value="F:superoxide dismutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.55.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001189">
        <property type="entry name" value="Mn/Fe_SOD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019833">
        <property type="entry name" value="Mn/Fe_SOD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019832">
        <property type="entry name" value="Mn/Fe_SOD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019831">
        <property type="entry name" value="Mn/Fe_SOD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036324">
        <property type="entry name" value="Mn/Fe_SOD_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036314">
        <property type="entry name" value="SOD_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02777">
        <property type="entry name" value="Sod_Fe_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00081">
        <property type="entry name" value="Sod_Fe_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000349">
        <property type="entry name" value="SODismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01703">
        <property type="entry name" value="MNSODISMTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46609">
        <property type="entry name" value="SSF46609"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54719">
        <property type="entry name" value="SSF54719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00088">
        <property type="entry name" value="SOD_MN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023024349" description="Superoxide dismutase" evidence="7">
        <location>
            <begin position="20"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="Sod_Fe_N" evidence="8">
        <location>
            <begin position="46"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="Sod_Fe_C" evidence="9">
        <location>
            <begin position="134"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000349-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD90147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="239" mass="27032" checksum="CBD453002288F873" modified="2019-11-13" version="1">MNKRKFLKQSILISIGAYIAPSVLLSACKSASIKDKNIKTTATGMFTLPELPYGYNAFPDTIDPLTMEIHYTKHHQGYTDKLNAALKDANIFGKTIEEILSMDNLSEAIRNNGGGYFNHSLYWDILTPGGTMSNAFKAKIIEDFGSEEAFMNELSEAGAKRFGSGWAWVVQDTDKKLRIFSTPNQDNPLMKVAEMNGTPILGIDVWEHAYYLKYQNKRTEYLNKILNIINWNKVEARML</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLC1</accession>
    <name>A0A5C6ZLC1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_04420</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="76" mass="8677" checksum="795494302371ECA4" modified="2019-11-13" version="1">MTKINFALLSKKDRIEIFNQTSINTGIPAYAVEKDWWVHLVLKVLFGMEIGNHLVFKGGTSLSKAWKIIQTKKRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLD3</accession>
    <name>A0A5C6ZLD3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphoheptose isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_00355</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="148" mass="17311" checksum="7E380378C2887243" modified="2019-11-13" version="1">MKREEADKFLHDKVERGEKISPVLPKGVKNYLIDIDGTITDDIPNEEPERMATCDPYPDALATCNKWYEKGHMICFFTSRTEEHREVTQDWLVKHGFKFHSLLMGKPRGGNYHWIDNHLVKATRYKGKFTELVNKNASIEVFDDEHDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLL0</accession>
    <name>A0A5C6ZLL0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Efflux transporter outer membrane subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_04085</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Lipid-anchor</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010131">
        <property type="entry name" value="RND_efflux_OM_lipoprot_NodT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01845">
        <property type="entry name" value="outer_NodT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0564">Palmitate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1134">Transmembrane beta strand</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023154559" evidence="2">
        <location>
            <begin position="25"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="470" mass="52416" checksum="06E3830C5BBA8676" modified="2019-11-13" version="1">MKNSIIIKFSVVIVTMLTLQSCFVAEDYTKQELKDVNIDEAKFRTDNLSQDTLTMADVSWKEMFSDPVLTQYIEKGLENNIDIRVALQQIIASEAYFKQGKASYYPTFSVNAQYTHQELAPNSQFGSFFDGALDQYDLTGALSWEADIWGKIRSNERAFQASYLQTVAAHQAVKTRLIANIASVYYQLLAVDEQIIITESTIETRSNGLETTKALKEAGNLTEVSVKQTEAQIYTAQGILVDLKNQSHILENTLSILLGDMPKEMERSTLAEQVVTTDLTLGVPSQLLSNRPDVIAAEFNLRNAFELTNVARSNFYPSLTLSASGGLQSLEFDKLFSANSIFATFIGGIAQPILNGRKIKTQYEVSQAQQEQARLNFKQSLLVASKEVSDAMFNYKSASEKIEIKQKEFNAYDLAIEYSQELLNYGLANYLEVLRAEENALNSSLDLVGAKNSQLQAIVDLYQALGGGWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLL4</accession>
    <name>A0A5C6ZLL4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">30S ribosomal protein S2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 8" type="primary">rpsB</name>
        <name evidence="8" type="ORF">ESY86_02035</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01425">
        <property type="entry name" value="RPS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00291_B">
        <property type="entry name" value="Ribosomal_S2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001865">
        <property type="entry name" value="Ribosomal_S2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005706">
        <property type="entry name" value="Ribosomal_S2_bac/mit/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018130">
        <property type="entry name" value="Ribosomal_S2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023591">
        <property type="entry name" value="Ribosomal_S2_flav_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12534">
        <property type="entry name" value="PTHR12534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00318">
        <property type="entry name" value="Ribosomal_S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00395">
        <property type="entry name" value="RIBOSOMALS2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52313">
        <property type="entry name" value="SSF52313"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01011">
        <property type="entry name" value="rpsB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00962">
        <property type="entry name" value="RIBOSOMAL_S2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00963">
        <property type="entry name" value="RIBOSOMAL_S2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="224"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="225"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="306"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD90765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="347" mass="38567" checksum="5FD230A6EE704712" modified="2019-11-13" version="1">MEKTTVKELLEAGVHFGHLTRKWDPNMAPYIYMERNGIHIINLYKTQAKIKETGEALQKIAASGKKILFVATKKQAKDIVAEKAGNVNMPYITERWPGGMLTNFVTIRKAVKKMAMIDRMKKDGTFNSLSKKERLQVDRQRAKLEKNLGSISDMTRLPGALFVVDIKREHIAIAEAQKLNIPIFAMVDTNSDPREVDYLIPSNDDASKSIEKIMSVVTSAVADGLAERKSEKTEKDAKDEKSTGDKKDKKELTPEEKAEKKAKKAEKAEKADDVEKAEGKEAKAEKKEAKAGNSEAIVESTAAKAENSEAKVEKTEAKTEKVEAKDEKTEVKTEKKAGTDVAANEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLN8</accession>
    <name>A0A5C6ZLN8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosomal protein L11 methyltransferase</fullName>
            <shortName evidence="2">L11 Mtase</shortName>
            <ecNumber evidence="2">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">prmA</name>
        <name evidence="3" type="ORF">ESY86_04295</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Methylates ribosomal protein L11.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>L-lysyl-[protein] + 3 S-adenosyl-L-methionine = 3 H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl-[protein] + 3 S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:54192"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:13826"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the methyltransferase superfamily. PrmA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008276">
        <property type="term" value="F:protein methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00735">
        <property type="entry name" value="Methyltr_PrmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004498">
        <property type="entry name" value="Ribosomal_PrmA_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000401">
        <property type="entry name" value="RPL11_MTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="277" mass="31324" checksum="7907A05835B7C393" modified="2019-11-13" version="1">MAEGYIEYQFKVEPLQPAVDILIAELGDAGFESFVETEAGVSAYIQKKEWHDGILDDTQILKSDEFEISYTSEAIEQTNWNVEWEKNFNAIVVDDMCSVRAPFHEKPNTKYDIIIEPKMSFGTGHHETTHMMIQHILKADLQDKSVLDMGCGTGVLAILAEMRGAKPIDAIDYDNWCYLNSLENVERNNCEHITVLEGDAQLLCGKNYDVIIANINRNILLQDLAVYAKALNSEGSLFLSGFYNEDIASIEAECERLGLKRSATLERNKWVALKFKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLQ8</accession>
    <name>A0A5C6ZLQ8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_05420</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="270" mass="29939" checksum="65EFC8C20F4A8456" modified="2019-11-13" version="1">MSKTKMLSLAAVTLLMAIGCKEPKKKDVKSPMATESEIISEASSITIEKLEGSPEYADASLKMMKSVEMKISKAGEVDFAFDVNNYELGAQTESKNADRLANSGKGQHIHFILNNQPYSAHYEPNFKKEIPEGVHHLVAFLSRSYHESVKNDNSVVVKKLMVGSDPKDVQDLDMEAPTLIYSRPKGEYAGKDTENLLLDFFVLNTTLSEKGNKVRATINGEVFMITEWAPQVIKGLPLGEVTINLELLDAEENLIPGVFNEVTRTVMLKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLR0</accession>
    <name>A0A5C6ZLR0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PhoH family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_01155</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003714">
        <property type="entry name" value="PhoH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02562">
        <property type="entry name" value="PhoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PhoH" evidence="3">
        <location>
            <begin position="108"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD91224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="317" mass="35702" checksum="512853D019CDAC73" modified="2019-11-13" version="1">MNELILELEEITPKEFFGAQNVNIELLKTYFPKLKIVARGNKIKAYGDEDLLEEFDLRMSMLMAHFGKYNKIDENVIERVLTSNSSEDYKTSDTSSEVIVHGVGGRLIRAQTVNQRKLVESVRHNDMVFAIGPAGTGKTYTCVALAVRALKNKEVKRIILTRPAVEAGENLGFLPGDLKEKLDPYMQPLYDALRDMIPAEKLALFIENGTIQIAPLAFMRGRTLDNAFVILDEGQNTTHAQMKMFLTRMGKSAKFLLTGDPGQVDLPRRTISGLKEALLVLKNVEGIGMIYLDDKDVIRHKLVKKVIEAYKSIENRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLZ6</accession>
    <name>A0A5C6ZLZ6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_00485</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="183" mass="20523" checksum="7F77FFF75832BDF3" modified="2019-11-13" version="1">MPTRNEVLKAIADINDSGNNTAAEMRTVLNLLLEHGEENPEPADGGANLDIFDVTQNSLKDEEDENAILGFSFRGFKKLHGNLTFNLTSKKIDPEKRDFFFKVTDEVALIFEELGIYKDTSRLAFVVPLIISDGKGYFPSILQIGFSDVNILWLEINHNFDNLRGKLSITSSIHFHLPANGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM03</accession>
    <name>A0A5C6ZM03_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Deoxyribose-phosphate aldolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_00890</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="226" mass="26148" checksum="8119C5282E4E8383" modified="2019-11-13" version="1">MLSAEDLIQKTIEISGSNKLKNAKLEFDFRDTHFKAVRQNGRFALEREFQADQGEVRDLLTNEGFVRFVNAEKVMLIDSMATAYAASVNSVHYFAVLPYDLDAASVNKELLQDVTIKDALYHTVKVTFNESGGGEDFDDEYLYWINTETFKIDYLAYSYEEEDGLGYRFREAYNERFVEGVRFVDYNNYKPKSNTMSLSDMPKLFNNGELELLSKIETENVRFTLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM48</accession>
    <name>A0A5C6ZM48_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_02625</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014942">
        <property type="entry name" value="AbiEii"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08843">
        <property type="entry name" value="AbiEii"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="269" mass="30676" checksum="AA4FAAEFEFB7154B" modified="2019-11-13" version="1">MKPILLELTAYCKEAGISFFVIGATARDIMMEMHNATSGRLTYDLDIAITVNDWEQWKKVEEEITNLKNFKKDPNQKQRFLYREKFPLDIVPLGDIMKTNHKIFWPPNEELAMSVLGFTAAGESALKVKIDNETEIKIASLTGIFILKIIAWKDRNQTNNKDADDIGFILGNYLSIHEERAATTYYEEVYAAEPFKSTTAGAVLLGKDINDLLKNHQETIAPILEILNEALNNKEESKLINQIIETHKSLNYEEVLQSIQNIVDGLRQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMA7</accession>
    <name>A0A5C6ZMA7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Outer membrane protein assembly factor BamD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">bamD</name>
        <name evidence="2" type="ORF">ESY86_01055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017689">
        <property type="entry name" value="BamD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039565">
        <property type="entry name" value="BamD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13525">
        <property type="entry name" value="YfiO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03302">
        <property type="entry name" value="OM_YfiO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YfiO" evidence="1">
        <location>
            <begin position="33"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="domain" description="YfiO" evidence="1">
        <location>
            <begin position="176"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="271" mass="32003" checksum="291A00F301D7B5D2" modified="2019-11-13" version="1">MKKLFYLLAFVSVISSCSEYQKALKSEDIATKFQMGTDLYDAGKYIKANRLFEQIVPKYRGKPQAEKLMYMHANAFYETRDYYISSYQFENFEKSYPQSEKAEEASFLGAKSFYHLSPVYSKEQNETIQALEKLQLFVNKYPNSQYLPQANELIQELDYKLEKKAFEIAKQYNKIAYFESSDYEAAITAFDNFLIEYPGTSFREQAMFYRLDSAYMLGINSVKYRQQERLETAMAFFKSFKRFYPESQLMVEATRMEMEMTSALQKFNTQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNC0</accession>
    <name>A0A5C6ZNC0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Acyl-CoA dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_03770</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00072">
        <property type="entry name" value="ACYL_COA_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="8">
        <location>
            <begin position="32"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="149"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="256"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD90493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="601" mass="66973" checksum="0A4DDA7E750F2B71" modified="2019-11-13" version="1">METTEKKDLLRGGQFIVKETKCEDVFTPEDFTEEQNMMKDAVMEFNEREIVAHRDRFENRDFAYTEECMTKAGELGFLGVAVPEEYGGLGMGFVSTVLTCDYISSGTGSFSTAFGAHTGIGTMPITLYGTEEQKQKYVPRLATGEWFGAYCLTEPGAGSDANSGKTIAALSEDGKSYKINGQKMWISNAGFCKLFIVFARLEKDKNITGFIVENDPKNGITMGEEEHKLGIRASSTRQVFFNDTVVPVENMLAGRGEGFKIAMNALNIGRIKLAAACLDSQRRIITTAVKYANERKQFDTRISDFGAIKVKIAEMSASAYAGESATYRASKDIEDRIAMREAAGNTHQEAELKGVEEYAIECSILKVAVSEDVQNCADEGIQIFGGMGFSEDTPMEAAWRDARIARIYEGTNEINRMLSVGLLVKKAMKGHVDLLGPAQKVQEELMGIPSFDTPDYSELFSEEKEIIQKLKKVFLMVAGGAVQKYGQELEAHQQLLIAAADILIEIYMAESAILRTEKNAKRFGEESQATQIAMSKLYLYHAVDIVEEKGKESIISFAEGDEQRMMLMGLRRFTKYQNYPDIVDLRKEIAEKVKEEEKYCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPN9</accession>
    <name>A0A5C6ZPN9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Efflux RND transporter periplasmic adaptor subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_04430</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HlyD_D23" evidence="2">
        <location>
            <begin position="54"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="352" mass="38272" checksum="8B50F92BEFF826BE" modified="2019-11-13" version="1">MKKRYIVFTLIVCGIIALIAYRISANSKINNPKNEKKTVNVMGVEGQVLEAQKFADNLTLSGTLEANEEIEIRSEISGIVESINFDEGAKVSKGQILFRVNDIELRAQLSKVQTAQQLASENQRRAKLLLEKQAISQEEFDVSKADFESARAESQLIAAQLSKTTVRAPFSGTIGLRSISKGTYVTPATPIANLVNTSQLKITFAIPEKYVSRMYAGSPLTFTTSNSKIVYNATIYAIEPQVDIATRTLKMRALADNKEGKLYPGTFANVTLPLETVNDALLVPTEALIPIQNGKKIFVSRGGKAKEVMVETGARTDSVARVLTGLKVGDTILTSGVMSLKNGTPVKVNLTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZR97</accession>
    <name>A0A5C6ZR97_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cytochrome c</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_00570</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00034">
        <property type="entry name" value="Cytochrom_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome c" evidence="5">
        <location>
            <begin position="45"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD91120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="151" mass="16480" checksum="F916929245C0668A" modified="2019-11-13" version="1">MKNSLIIILAVLMFCACNTTEKKQGLAVASSSELKPVKQDSELSESIARGESIYTDFCMSCHLPNGQGVANVYPPLANSDYLKNKQTESIKAIKYGLSGKIVVNGSPYNNVMSPMGLEDDETVDVMNYINNSWGNTFGTLITETQVSKIEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZRC2</accession>
    <name>A0A5C6ZRC2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_00695</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="140" mass="16362" checksum="2437D8EF8710B3E5" modified="2019-11-13" version="1">MSSKYLLIAILSAVLMSCSKDPSPMIPHLSGYWEIDEVTMPNGQIKDYNYNATIDYIELTDSLSGFRKKLRPNFKGTYETSQSEEQLQIKIENDSLNIYYSTPFAQWKETVLKANETELLIINDRKVRYLYRQYEPLDLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6Z9J9</accession>
    <name>A0A5C6Z9J9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_20245</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000061">
        <property type="protein sequence ID" value="TXD86428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05483">
        <property type="entry name" value="retropepsin_like_bacteria"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034122">
        <property type="entry name" value="Retropepsin-like_bacterial"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="SSF50630"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="393" mass="45136" checksum="628E1EEFA71A3201" modified="2019-11-13" version="1">MDTKRIYNLIIFISYLGFGQEFNSGTNQKDFYTEFRYEWINEKIIIPVEIEGQIYRFLLDTGAPNLITTNLNKKITTNFKQTIPITDANNKKDSLDLVTIPLIKISGISYFNIPSLVSKTETNLIFDCFKIDGLIGSNLLRNSIIQILPKEKLIKLTDDKKKLSLKRKNSTEIEFPDIQSTPYVWIELNSNGIANDQVYVDTGMSGFYTMANGHLEIFQKDDIFKIDAETKGSQGTGLFGSENENTYYQLIVPKIEINKAIFNEITVVTTSDNNSRIGSEILLYGNVTIDFLNKRFYYEPFENIVDLREKTFGFIPTIIDDKFVIGLVWADDLKDKIKFGDQILEINGRSLLNSDFCDLITEKNIFKNNEKLDLIILQKDGEKKALIVNKNYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAN6</accession>
    <name>A0A5C6ZAN6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19920</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000052">
        <property type="protein sequence ID" value="TXD86548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="167" mass="19678" checksum="EC9C100D6557661F" modified="2019-11-13" version="1">MKKIALTFIFLISINVFSQEEKRIFNSEFEKFVLQCETIGRTITNKDIETEFSNWYEGIDSEKLNLEVKQLESDIKNSELEVTYSLIMMSENPLIYSFHFYNEITKTEYGQLFIRFADRENNLVDDIKVVSKTQLEEINKESEIELENMNIPPPPPPPPIKKKKNEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAZ0</accession>
    <name>A0A5C6ZAZ0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Site-specific integrase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_18925</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000035">
        <property type="protein sequence ID" value="TXD86886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035386">
        <property type="entry name" value="Arm-DNA-bind_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025269">
        <property type="entry name" value="SAM-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17293">
        <property type="entry name" value="Arm-DNA-bind_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13102">
        <property type="entry name" value="Phage_int_SAM_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="3">
        <location>
            <begin position="219"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD86886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="416" mass="48501" checksum="F7642B975B0244A0" modified="2019-11-13" version="1">MKNTFSTLFYLKDERKDKNGKAGLYLRITANGRRTTISMHRKIDPEKWDSRMNKLRGKGTEVGEISNLMTNVRHKVYRIQNKLFDKGDPFTAQDIKDLYIGKKDKPKMLLEIFNEHNKQMKKLIDIEFALGTYKRYFTTRNHISEYLKTSYNMQDIPIRDVNLKFIRGFEYFLKEIKVCNHNSALKYVNNFKKIIRIAVGNEWITKDPFYNYKIKFKTVERDYLSQEEIDELINKEIKGSRLSVVRDMFVFCCYTGLSYIDIQKLTDNNIVMEIDGALRIQANRTKTKSKLGIPLLPPALAILEKYKKHPKVINGDCLIPVLSNQKSNAYLKEIAEVCGIKKNLTTHLARHTFATTVTLSNGVPIETVGKLLGHKNLRTTQHYAKIIDRKVNEDMKILQKKMATEKKNNKDLTQKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBM5</accession>
    <name>A0A5C6ZBM5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19495</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000041">
        <property type="protein sequence ID" value="TXD86726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="264" mass="30171" checksum="C1BAE47F8C82807E" modified="2019-11-13" version="1">MKINTLFSRFAIALGLCFALNVKGQTVNTEWATKINQTFAGIDKDRIPHSLLRDYAMEFTDLSNYNGTLSDTNYVSRGALKSIYNTLVMARVKPTVTSLVSPSVFRQNWNNLRQENTLVISGLYYKYSQLKSNAYPNFITVSNNKLYDKYVNGVWQNPYEVKQVFAMTTPITKFKGLTIDVQLPQSLWYTNQASSVQNIAIDFDNGAGYINMPFGGSYQLQYTEEGIYDWTYKLTLTNGQILYSQSRVIFEETAPTKSWSNRKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBP7</accession>
    <name>A0A5C6ZBP7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000039">
        <property type="protein sequence ID" value="TXD86763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01300">
        <property type="entry name" value="YtcJ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013108">
        <property type="entry name" value="Amidohydro_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033932">
        <property type="entry name" value="YtcJ-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07969">
        <property type="entry name" value="Amidohydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro_3" evidence="1">
        <location>
            <begin position="70"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="544" mass="61064" checksum="6F5AD2304607FC2B" modified="2019-11-13" version="1">MKHFYLLLIGLSLFSCQDEKPSADSIYINANIYTVDTNFTQAEAFAIKDGKFLEIGTAEALKSKYAADTLIDVQGKTILPGLVDAHCHFLTLGQLQQQVNLVGTTSFDDMIKRVLDFQNKNKMAYLRGRGWDQNDWEDKNMPTKTLLDKLFPDTPIALTRIDGHASFCNQAALDLGNITTETKIDGGEVEVINGKLTGILYDNAEQLVMNNWPKPSKKQLIEALMSAQQICFDNGLTSLSDAGPDIFTSPWIENIELIDSLQKSGDLKIRLYMMVPGTKPNLDYYLNKGTYKTERLNVRSFKFYADGALGSRGALLRAPYSDKDHHYGLPVMSYQEINAASKRIAASEFQMNTHAIGDSANHEVLEIYKAALGAKKDRRWRIEHAQVVSPEDFKYFDGILPSIQPTHATSDMYWAEDRLGEQRIKDAYAYKQLLNAYGKIALGTDFPVEQVNPMLTFYAAVARQDTKDFPENGFQTENALTREEALKGMTIWAAHSNFEETEKGSIEAGKFADFIVLDRDIMTVPLKDVIETKVEQTFVGGELQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBQ7</accession>
    <name>A0A5C6ZBQ7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20195</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000060">
        <property type="protein sequence ID" value="TXD86438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="137" mass="15782" checksum="077D04EEB599B38C" modified="2019-11-13" version="1">MDSSLIGIGIALGISFFILYTRKKKWMTEKIVWLICIGLLAFGLFGFLYSESEFRSDRIMYFGFCVPIIYWISDRIFKRISENIHQRDFILFLRYSDEINDGFGAKNPQVKGSDKLFSFGLLTIIVVTLLIGIGTIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBS5</accession>
    <name>A0A5C6ZBS5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">TatD family deoxyribonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19275</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000038">
        <property type="protein sequence ID" value="TXD86796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004536">
        <property type="term" value="F:deoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01310">
        <property type="entry name" value="TatD_DNAse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018228">
        <property type="entry name" value="DNase_TatD-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015991">
        <property type="entry name" value="Hydrolase_TatD-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001130">
        <property type="entry name" value="TatD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01026">
        <property type="entry name" value="TatD_DNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005902">
        <property type="entry name" value="DNase_TatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00010">
        <property type="entry name" value="TIGR00010"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01090">
        <property type="entry name" value="TATD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="255" mass="29262" checksum="6E242DD86248ECF6" modified="2019-11-13" version="1">MTITDTHTHLYSEAFDEDRAEMIARAQAQNVKRFFIPAIDSSYTPAMLQLQLDHPDQVFLMAGLHPTHVKENYEAELQHVEEQLANHQYYAIGEIGIDLYWDKTTLAMQQKAFRRQIQLAKQHGLPIVIHCREAFDEIFEILADEKDEKLFGIFHCFTGTLEQARQAISYNMTLGIGGVATFKNGKIDQFLNQIDLKHIVLETDSPYLAPKPFRGKRNESAYIVKVLEKLAEIYSVSEEKIAEITTENSKAIFKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBZ3</accession>
    <name>A0A5C6ZBZ3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20655</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000099">
        <property type="protein sequence ID" value="TXD86022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="26"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="225" mass="26535" checksum="C3036B5F0502F8EC" modified="2019-11-13" version="1">MKKIPFLILTLIFISSCEFNSNKLEWNKLNDEIVQKDKQISELQKKIKDLEKDTKNTQSSDYYRFVESSDSEINVAEKLKTGERKLIDKKDFKDTLDISDNFFVYKHTSEITQTSKSEFESILRDFDQFKSEYGNDFFVRVMTFYNGQSLPLETENSKTDIHILIQPTELGYENKTFVISDFYDVNIKTLEKKNNSVELTFEHGKFPRKKELIIIKPELVKFGNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC69</accession>
    <name>A0A5C6ZC69_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19915</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000052">
        <property type="protein sequence ID" value="TXD86547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="162" mass="19404" checksum="EF6D6A2A84B92950" modified="2019-11-13" version="1">MNENEDYFRISKNGNIHTLSDRIPFKWKELIGWTSASFVFLIYFFGFGIGIFIAILTLIGYTSYRFASWIYYTELLINEKTGNMIRLKKLFDRVQKTELITEKLNPNRFEYSELKRSGKTKYLMNYRTHKNNELLILKNKTDKDIIEKYIAEKITVYNTVYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCC0</accession>
    <name>A0A5C6ZCC0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_16805</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000024">
        <property type="protein sequence ID" value="TXD87439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="163" mass="19235" checksum="8850F692755AC0C5" modified="2019-11-13" version="1">MIKKIINNLKVRSIQSYVYRMETYVPYLEKEPFKFDLKIDRQSGRCTKYYIEKNDLLIHQSYIYNEVFLLRLIKKRGPVIGNCFTHPEFRGKSIYPYVINCIAKNSLNLGAKEVFVIVNQSNAGSIKGIEKAGFEKYVSIDTKRWLIFYIKPRVEYSKNILSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCS6</accession>
    <name>A0A5C6ZCS6_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Hva1_TUDOR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18935</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000035">
        <property type="protein sequence ID" value="TXD86887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021331">
        <property type="entry name" value="Hva1_TUDOR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11160">
        <property type="entry name" value="Hva1_TUDOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hva1_TUDOR" evidence="1">
        <location>
            <begin position="5"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="70" mass="7852" checksum="583A958C72AD37B0" modified="2019-11-13" version="1">MIKKGTEVTWKWGSGTAKGKVQQTYTEKVTKTIKGTEVTRNGEKNDKALYIQQEDGDYVLKSESEVKPAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCT4</accession>
    <name>A0A5C6ZCT4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18985</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000035">
        <property type="protein sequence ID" value="TXD86897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027395">
        <property type="entry name" value="WH_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13601">
        <property type="entry name" value="HTH_34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_34" evidence="1">
        <location>
            <begin position="15"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="97" mass="11166" checksum="4731F593A429A4B9" modified="2019-11-13" version="1">MSIINNINKVFDHRIRLGIMSVLMVNEYADFNMLKELLAATDGNLASHTKALEKADYIWVEKQFIGRKPNTRYATTTLGRAEFNKHIEALEKLINNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCY8</accession>
    <name>A0A5C6ZCY8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyl-CoA desaturase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_16565</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000023">
        <property type="protein sequence ID" value="TXD87507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012171">
        <property type="entry name" value="Fatty_acid_desaturase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19353">
        <property type="entry name" value="PTHR19353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015921">
        <property type="entry name" value="FA_sphinglp_des"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="203"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="235"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="FA_desaturase" evidence="2">
        <location>
            <begin position="65"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="366" mass="42480" checksum="42554F00E5C5C344" modified="2019-11-13" version="1">MTKQTLSFSRADSAKFFRTLNKRVNNYFKENNIKRTGNWKLWLKTIIMFTIFLLPYLLILTLDIPGWLQLLLTVVMGIGMAGVGMNVMHDGNHGAFSNKDWVNRLMGSSIYILAGNVYNWKVQHNVLHHTYTNIHGHDEDLEAGRILRFSEHTKWAKHHKFQHYYSVLLYGLLTINWAITTDWQQMTRYMKRKLSYGKMPSPIANWSKLVISKIIYVSLWIVLPMLVLDAAWWKILLGFFIMHYVAGLILSVVFQLAHVMDEAEMPLPAENGTMKNTWAIHQLETTINFGAKSKIINWYTGGLNHQVEHHIFPNISHIHYGKIAKIVKETAQEFNLPYKEYETTRKAIVAHFKFLKTMGMKPAVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD22</accession>
    <name>A0A5C6ZD22_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">50S ribosomal protein L25</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">General stress protein CTC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rplY</name>
        <name evidence="6" type="synonym">ctc</name>
        <name evidence="9" type="ORF">ESY86_18480</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000031">
        <property type="protein sequence ID" value="TXD87044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008097">
        <property type="term" value="F:5S rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00495">
        <property type="entry name" value="Ribosomal_L25_TL5_CTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.120.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.240.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01334">
        <property type="entry name" value="Ribosomal_L25_CTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020056">
        <property type="entry name" value="Rbsml_L25/Gln-tRNA_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029751">
        <property type="entry name" value="Ribosomal_L25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011035">
        <property type="entry name" value="Ribosomal_L25/Gln-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020057">
        <property type="entry name" value="Ribosomal_L25_b-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037121">
        <property type="entry name" value="Ribosomal_L25_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001021">
        <property type="entry name" value="Ribosomal_L25_long"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01386">
        <property type="entry name" value="Ribosomal_L25p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14693">
        <property type="entry name" value="Ribosomal_TL5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50715">
        <property type="entry name" value="SSF50715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00731">
        <property type="entry name" value="bL25_bact_ctc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_TL5_C" evidence="8">
        <location>
            <begin position="101"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="190"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="190"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF14693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD87044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="222" mass="24352" checksum="BB60D3057542DCED" modified="2019-11-13" version="1">MKSITINGSKRESVGKKAAKALRNADMVPCVLYGGEGKSTMHFAAPELAFSKLVYTPSAHTVEIAIEGGETYEAVLQDIQFHPVTDRILHVDFFQLFEDREISMEIPVHVIGTSKGVLAGGILRRNRRKLRVRALPKNLPDFLEADISPLKIGDKLYVTELEGEGYELLHTDNTVVCQIKTARAVVIIEDEDEDDELEEGAEGTAEGAEGAETPAEDAESKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDE5</accession>
    <name>A0A5C6ZDE5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NAD kinase</fullName>
            <ecNumber evidence="5">2.7.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">ATP-dependent NAD kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nadK</name>
        <name evidence="6" type="ORF">ESY86_14680</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + NAD(+) = ADP + H(+) + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:18629"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the NAD kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.23" evidence="5"/>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003951">
        <property type="term" value="F:NAD+ kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019674">
        <property type="term" value="P:NAD metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006741">
        <property type="term" value="P:NADP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00361">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017437">
        <property type="entry name" value="ATP-NAD_kinase_PpnK-typ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002504">
        <property type="entry name" value="NADK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01513">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="SSF111331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 5" id="KW-0520">NAD</keyword>
    <keyword evidence="3 5" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5 6" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="71"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="71"/>
            <end position="72"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="146"/>
            <end position="147"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="187"/>
            <end position="192"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="211"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD87913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="291" mass="32522" checksum="771249B3F441CC65" modified="2019-11-13" version="1">MKIAVYSQYFDGKSTEYFEQLLEILLTKEVSVFIESEFRQKLDLPLLKDKRLQSFTSLDESFDLLISVGGDGTILRAVTFLRDFSIPIVGINTGRLGFLATIQVNHVELAINEILKGNYKISERSLLTVETNPKNMALQSINFALNEVAISRKNTTSMISVDTHLDGEYLTSYWSDGLIISTPTGSTGYSLSCGGPVITPDTESLVLTPIAPHNLNARPLVIPDATVIQLKVNGREDNYLISLDSRIATLSNDTIVTIKKANFKIKMLQVLEESFIDTLRKKLLWGEDRRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDJ1</accession>
    <name>A0A5C6ZDJ1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF3341 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_14365</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021776">
        <property type="entry name" value="ActD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11821">
        <property type="entry name" value="DUF3341"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="176" mass="19999" checksum="B17F344B68C4FC98" modified="2019-11-13" version="1">MEASKVIHAIYTDDDVLMAAVKKVSSAHHHIEEIFTPFPVHGLDKAMGLAPTRIAITSFLYGCVGLAVSIWMMNYIMIEDWPQDIGGKPSFSFIENMPAFVPIMFELTVFFAAHLMVITFYLRSRLWPFKKAENPDPRTTDDHFLMEISVNNNEKELTDLLRETGAVEINLINKAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDL7</accession>
    <name>A0A5C6ZDL7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Potassium transporter TrkA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_16490</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02080">
        <property type="entry name" value="TrkA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="65"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="5">
        <location>
            <begin position="141"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="233"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="233"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD87626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="262" mass="29725" checksum="C6286A580DE88375" modified="2019-11-13" version="1">MIAAVTLFIVVTLSALITRIAAIALVHTGLSTQIARFQARSAYTGAGYSTSESEKIMNHPVRRKIIFNLMLIGNAGIVTVMSSLILTFVLPDTLSSKLYGLGIVLVGMMILSWAVKSDMVDRALSKLINRMLKRYTDLDIQDYASVLHLKDDYKISEKHIDAEDWMCNQTLLELDLRREGITILGVDRKNDRYYGSPDGDFKLLSDDVITIYGKSNGIRNLYNRKKGFKAEMDHQRYMKKEEKRQETQHQSEADEEHADTEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDM4</accession>
    <name>A0A5C6ZDM4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycerophosphodiester phosphodiesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_16155</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030395">
        <property type="entry name" value="GP_PDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03009">
        <property type="entry name" value="GDPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="SSF51695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51704">
        <property type="entry name" value="GP_PDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GP-PDE" evidence="1">
        <location>
            <begin position="21"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="289" mass="32567" checksum="850572A590945F40" modified="2019-11-13" version="1">MRRVLVLCVLMVFNCKSMKKIDIQGHRGCRGLLPENSLPAFQKALDLGVTTLELDVIISADNKVVVSHEPYLNHEIALDLSGKPITEANELSYNLYQMPYDSIKKYDCGSKPHPRFPNQIKQKVYKPLLTEVIALAETQSGHKIQYNIEIKSSPKTDGVFTPSVEAYVALVLKIITAEGILERTTLQSFDVRALELFHATAPSVKSALLVDEDESISKKLELLSFEPDVISPYFELLEAKWVSEYQQMGYQIIPWTVNTEADILRMLAFDVDGIISDYPDRVISMNNSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDQ3</accession>
    <name>A0A5C6ZDQ3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF3467 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_16330</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021857">
        <property type="entry name" value="DUF3467"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11950">
        <property type="entry name" value="DUF3467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="112" mass="12401" checksum="07A1CAF0CA727C85" modified="2019-11-13" version="1">MAEENNNNNNNKSKKKNQGINIELDEKVAEGTYSNLAIINHSVSEFVVDFVSVMPGTPKSKVKSRIILTPQHAKRLLKALGDNVNRFEKAHGEIKDYEQAPIPLNFGPTGQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDW6</accession>
    <name>A0A5C6ZDW6_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">30S ribosomal protein S19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">rpsS</name>
        <name evidence="7" type="ORF">ESY86_14850</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00531">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020934">
        <property type="entry name" value="Ribosomal_S15/S19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002222">
        <property type="entry name" value="Ribosomal_S19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005732">
        <property type="entry name" value="Ribosomal_S19_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023575">
        <property type="entry name" value="Ribosomal_S19_S15_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880">
        <property type="entry name" value="PTHR11880"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00203">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002144">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00975">
        <property type="entry name" value="RIBOSOMALS19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54570">
        <property type="entry name" value="SSF54570"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01050">
        <property type="entry name" value="rpsS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00323">
        <property type="entry name" value="RIBOSOMAL_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD87945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="92" mass="10272" checksum="B59CA6BA2A5BB09B" modified="2019-11-13" version="1">MARSLKKGPFIHYKLDKKVAENVASNKKTVIKTWSRASMISPDFVGQTIAVHNGRQFVPVYVTENMVGHKLGEFSPTRSFRGHTGAKNKGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE21</accession>
    <name>A0A5C6ZE21_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Invasin_D3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15805</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008964">
        <property type="entry name" value="Invasin/intimin_cell_adhesion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015217">
        <property type="entry name" value="Invasin_dom_3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09134">
        <property type="entry name" value="Invasin_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49373">
        <property type="entry name" value="SSF49373"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Invasin_D3" evidence="1">
        <location>
            <begin position="415"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="2131" mass="239888" checksum="AD189B0A36F6C549" modified="2019-11-13" version="1">MGFINTYKISNEGTNNSYTDSISKEFIENSTSFVYTIARTANGKCLLSKLDILGGIVWSKEINNQDVGAEPLYIEATSTNPIQYTAISNNADSVNSFIYLITFDVNGNIVKIKKLQFPRFGGQEGVHVQYYNNYFLIAYNKNVIKVNSDGVVSNIWQFSNQKYAVGPAFSFFVDPISGYMLSFHQVFQDGVAYLVLRDENFVVVEEIQLLYPNASSGSVPADAVFKKANNTYYYYFTISQDFSNINREVCMVKTQNAQITYQKIIQLQKNSNLLSNFTLVDNHIYFHSFYGIMKLSTDDLTLLWTKKINSFNQIIRLIYNSSTSNITCIYNDFSGDYNYNSKAFLVDKELNSCLTILQDVPTLNSGVIGFSVTSDFAKSDELIITSESISNDLTNVELIIDELCPPSGSGNYNLEKSAIFANPGTITADGIDASFITVQLKDSSENNITVGGEAVIIFSSLGNISGVTENNDGTYTAVLTSSNIGNAALSFSVNNQLSNNTANVNFVEKTFEIPISELTSLQSPNFYIQSVGSRGIESTKGIHLRWIFGGVLGEKHLPKRDYAQTDHNFNKPNDVVKVYRTRYQKVQFNLNLFERPTVINDTNKFWIYRFANGGDSYYQFSEAREFHVYFRNTSKYNQVRASINPLLNPSGFLQNYGSELIEIENKKELFFAAEFKAINLSTSSALQTESLSVSENNQFALKKMSSRQTFSSSQLSEARLVCENGKSIRFKSSECFVSEISFEFYADFISAVNKRDGWQPIGDFGLTLDDGLVHSMLEPEPGLVQGKWQRFNDNAFVNVENYKIKWDRPTEDWDRDIKQIVNNYIQLSNSATNPTAIELVPFENDDDEPIEITNLDQLNFAAYDYHIARMLGLGVLDVDVAVFENTYIYIAEYTTFGDLEDGLGKRETHHLSMGLPTSIDDERLPIPVNIREVTPGAFIGNEGEPANITDVGGYTQNGESRYVTLFAENQPTDLIGTTFYDTADEFALEKFTYPVYSGIEYKKVLSGQTCDDGEWQKPELPNDPEYLNAVPLGEVEHFETRVLQISETNQPLFVHKQDVSGLHCYSSYGINWFSRATSSSIIKSIQTLLKPKNSLLPPSNINSLLIRSESPLLLTSEEEQDRLKAINPNPESETVEDETLVRITFDYHTYQDLINRKVLLDSVVTNNDILDPNLDDNRAILYPDNEEVFADDVDIFFRPQVPDNVSGKALPLSATNQPSNILLSNIQTVDYQRASTGEINPITNVFEPEIISPTLQPGTESNYVGGAFILGNQQHIIHSVIQGTDGPIFSVYKKEISDALVNNIPSADADNLQPIEISEDGFFMAVENMQNASSWGTPNPLPLKVNVAVNNEIHREILEILDDDGIMERHVEKSRGIWSEPLDGNATIEKVEEPYEAIYDSEGNITGYNERHRGNYKITFQNIKLTQHPQYNKEGVSVEWFRGIARIFTQGSLQDGIARKTRKVLSVVKIDNIVYPGDANENDLVIYVNDSSFPEVNEDEDLVNDIEYDYIQTGTNISVNFYPSYKVYLYVDTTYGLNETNLLPEAGDGTKYSIFGLRSRDLDLEQYASKICVPSLMFAQEMIEALPPEQPQGPLYATRPDFFGRSTLTLTTQYEHEPHGLLFYRTNDEALLNALYAKSTIIEIRESLKALGGNDEVDFTSRWQNFMKLEALKIDGDYKEFPSGEIDAENRFKFPNPDKLALFTNANEIINNINNGIISPPNPPIALFNIDLNDANNDIGAIPAGDERIFGFVKATIYNAFVPLTEVPIIYQHIEGADYKPVNEKQVIRDRNGYVLPPNHQDFKMAPMMKIINTNPHETQFVDFSLDGTSNNIYFYGVREISSQMKMGDYSPFLGPVKLVNTNAPETPEIKRIMPVLENAVLGISPSIQLEINAYPEVQDIKKLTIYRAFNKLDAQSVRTMQQVKIIDLETLGIINDATWKVQDTFEDLDEVPYGDGLFYRITVSRKVEYADKNGNIVIEYQPSQASKIVASMMVEVTNPPAPILNFTSDPLINNGKELPNIILQWDNTCYNGKYHVYKMNNNGTWVNIANLKTNNTNIILPLADTNLNSGTLQIRNEDYDPIYHHFKVVAENTSGMMSIEENILTIPNTDILTNGEGIGFMIVEDTNIVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE81</accession>
    <name>A0A5C6ZE81_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Sugar transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_16760</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial sugar transferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000024">
        <property type="protein sequence ID" value="TXD87430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003362">
        <property type="entry name" value="Bact_transf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017475">
        <property type="entry name" value="EPS_sugar_tfrase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02397">
        <property type="entry name" value="Bac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03025">
        <property type="entry name" value="EPS_sugtrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="110"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="282"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="Bac_transf" evidence="8">
        <location>
            <begin position="278"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD87430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="464" mass="54129" checksum="E353710B074317E9" modified="2019-11-13" version="1">MGKKKNIHFEVSERKILLRLMDLFVVFFGLYCLELSSSFDYLQIRPDNWLALAVLAVYILAFGTVFEIYNLQKSSELDTVFRNIVLTVSVTVLFYMLTPVLTPFLPMNRFQILFFFLCMVFSLFVWRFAYINFVSSPRFYKKVLLVGEISNIENIVQPLRQMDPNYKIVGFINCETKTEASVNTTGLIEFEGHALLEVIKGEKVSEILIATYNSEIITTSIYRDLIHLLDRGFIIREYTQVYEELTRRVPIQFIGKDFYKFFPFSRSNQNTLYLFFHRLFDLIFSVIGLVFGLCLLPIVLIGNLMGNRGPVFYIQDRVGKNGKVFKIYKLRTMVTDAEVSGAKWAQKDDVRITRFGKFLRRSRLDEVPQFMNVLKAEMSIIGPRPERPFFVRELAGVVPFYETRHIVKPGLTGWAQVNTRYGASVDDSLTKLQYDLYYIKHRSLFLDLNIVVKTFSTIIYYRGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE90</accession>
    <name>A0A5C6ZE90_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">O-antigen ligase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_16790</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000024">
        <property type="protein sequence ID" value="TXD87436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007016">
        <property type="entry name" value="O-antigen_ligase-related"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04932">
        <property type="entry name" value="Wzy_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="61"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="90"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="168"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="210"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="238"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="263"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="291"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="382"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="412"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD87436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="461" mass="51600" checksum="7DC8F946E4780B72" modified="2019-11-13" version="1">MQAKRRKRYRFTNDTYVALVVLHILMGVFINLIPQFSTVYFSLVCAFFVLKIIVTGKHEKLIWVLFGASYFVAAESLFRMTGGGLFYEFSKYFVILLMLMGMFFDGLSGKGYPYFIYLILLVPSILVASTTLGYDLNFRTSIAFVLSGPVCLGVSALYCYGKKVSMQVLLQIVACMSYPIITMATHLFLYNPSVKEVLTSTGSNYATSGGFGPNQVSTLLGLGMFALTVRFFMKSPSLFLKLFNLVLLAAVSFRALVTLSRGGVLAAVLVIGAFLVIYFGRSKYQQKQQIIVSVLLLLFVSLLTWVISLNQSSGLVGNRYSNEDALGREKKDVSTGRVDLFVDEFAGFKEHPFLGVGANGMKQERLEDTGKITASHNEISRLLSEHGIFGVLILIILIFKPLDFRSRNRNNIFFYSFLAFWFATINHSAMRIAAPAFIYALALLNVTHEKPPLPRKQFKPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEK5</accession>
    <name>A0A5C6ZEK5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sterol desaturase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_16150</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006694">
        <property type="entry name" value="Fatty_acid_hydroxylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04116">
        <property type="entry name" value="FA_hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="150"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid hydroxylase" evidence="2">
        <location>
            <begin position="96"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="280" mass="32381" checksum="2EE5F16A35A752A1" modified="2019-11-13" version="1">MESIINYFETIPSLHRSLILVGGLTFFWVLEGTLPLFNFKYKKWQHAWPNIFLTLTTIVVNFSLAFLLIFTADWVTTHNFGIINWIPNLPLWGYVLLGVLLLDFIGAYLAHYVEHKVKPLWMVHLVHHTDHNVDTTTANRHHPLESVIRFGFTLAGVFIVGTPIAIVFLYQSLSLVATQFTHANIKMPRQLDKLMSYVLVSPDMHKVHHHYVLPYTDSNFGNIFSIWDRLFGTFMILDRDNIVYGVDTFPDEVANGKISTLLKQPFHKYRKPTNAKISEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEL1</accession>
    <name>A0A5C6ZEL1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Acyl-CoA dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_16220</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00072">
        <property type="entry name" value="ACYL_COA_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="8">
        <location>
            <begin position="7"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="124"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="231"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD87582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="388" mass="43743" checksum="50FDFCAD8FD819CD" modified="2019-11-13" version="1">MDSRYFTEEHELFRQSLKDFLQKEVVPHIDKWEETGHIERFIWKKFGDMGFFGIPYPEEFGGLDLDLFYTVILLEELQKINSGGFAAAIWAHAYLAMTHLNKEGDQAIKEKYLAPSIAGDMIGCLCITEPFGGSDVAGMRSTAVKKGDTYVINGSKTFITNGVLSDYLVVAAKTSPELGNKGLSIFVIDRDTPGISATKLDKLGWRASDTGEIAFDNVTIPASNLMGEEDMGFPYIMQHFALERLIMGINAHARAEFALEYALEYMKTREAFGRTIDKFQALRHKIADLYTEMEICKEFNYSVAYRLNKGEYVVKEATMSKLQCTKMSDEVIYQCLQFLGGYGYMEDYPMARLSRDSRLGPIGGGTSEILREIIAKMVIDKKDYKPAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEL5</accession>
    <name>A0A5C6ZEL5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_12865</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the purine-cytosine permease (2.A.39) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015209">
        <property type="term" value="F:cytosine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030191">
        <property type="entry name" value="CodB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001248">
        <property type="entry name" value="Pur-cyt_permease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30569">
        <property type="entry name" value="PTHR30569"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02133">
        <property type="entry name" value="Transp_cyt_pur"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="104"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="168"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="209"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="241"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="281"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="320"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="344"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="377"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="401"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD88405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="432" mass="47042" checksum="7F9AA91330C2AC5B" modified="2019-11-13" version="1">MENTVTNSQEHTDYASEAIPENARQPWYVPAFIFGGLEFCIPVLLIGGILIGNFSLLEIIGILMIALVFFQWIGNAIQGYIGAKTGLTSSALASLSFGKEQSRIIVGIVILALTLGWWAIQTSVAADAFSALVGINKDENFLLYILSTAGIGILFAIPSILGYASIKWVDYVAIPAGLLLVTVALYLSINNMGWEKITTWNPEGSMSFIGAINLVISINVAQWLIAPDYTRFAKPTWRDNILIPLGIIIVGFPLFIVGGIMSMGTGNSDIVQVMQELGFPAWGFVVLWVATWTSQLVSNYTGGLVLCNMFNLHDNKGRKTMTLVFAVIGIILALLGIMDQFVNFLYTLALIVPVIAGVIMAHYFFVSKTVFTTEKSWNWLATISIMTGLLVGYLTQYQFPIGIPAVQSLIVSGALYAVLNNTLKIELSGKNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEQ8</accession>
    <name>A0A5C6ZEQ8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Trimeric intracellular cation channel family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_15920</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0126 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000021">
        <property type="protein sequence ID" value="TXD87647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005115">
        <property type="entry name" value="Gly_transporter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03458">
        <property type="entry name" value="Gly_transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="62"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="Gly_transporter" evidence="8">
        <location>
            <begin position="5"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="Gly_transporter" evidence="8">
        <location>
            <begin position="91"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF03458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD87647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="204" mass="22317" checksum="4E22DB2FE0D51F9A" modified="2019-11-13" version="1">MFIQIIDILGTIAFAISGVLVALDKRMDAFGVLIIAFVTAVGGGTLRDVMIGIEPVSWMRDMTYVYVIIGSAFFAVLLRQKINYLRTSLFLFDTIGLGLYTVVGIETGLVAGLKPIICIALGTMTACFGGVIRDILCNEIPVIFRRKEIYATACILGGLSYFLLLKVMGDSNFVFILSGLIVIITRLLAVRFNLGLPSLYKKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZES3</accession>
    <name>A0A5C6ZES3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000027">
        <property type="protein sequence ID" value="TXD87271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000801">
        <property type="entry name" value="Esterase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00756">
        <property type="entry name" value="Esterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023079962" evidence="1">
        <location>
            <begin position="21"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="271" mass="30963" checksum="CD883753A84C5C5A" modified="2019-11-13" version="1">MKITIISILFILLTLGFLHAQSTAGSQVSKFKIAAPQLDTQKIIWVYTPKSYKKSKKNYPVIYMFDAQNLFDAETSYVGEWKIDEYLDRLTENQVIIVGIEHGNDKRLEELTPYPNEKYGGGKGDDFLDFMINTVKPHIDISYRTKTDAPNTSIFGSSLGGLMACYAVIKHPKTFGSAGVFSPAFWINPEIYELVETTELPESAYFYFMAGDQEDENMITDQQKMLRLLTEKGIPNDHIKTKVIKGGTHNEALWRNQFPEAFEWLNQRAFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZET3</accession>
    <name>A0A5C6ZET3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_17595</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000027">
        <property type="protein sequence ID" value="TXD87248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011495">
        <property type="entry name" value="Sig_transdc_His_kin_sub2_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07568">
        <property type="entry name" value="HisKA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022760842" evidence="3">
        <location>
            <begin position="20"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="383"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="domain" description="HATPase_c" evidence="4">
        <location>
            <begin position="528"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="406"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD87248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="627" mass="71380" checksum="F7D9AB7AE37CAD6B" modified="2019-11-13" version="1">MKHSLTAVFLLYFTTFFHAQNSDTVKLDSLLIWLDSHIKIPTDSAAIANHSYRAISLSKKINNQDALAKTFGYLATYHKDYSKLDLAFYYVEKLRDIHLEQNNDDQLVFTYLKWKDLLMVKADYAEATQTVYKALDLFEKTNNQKGIAECYTAIGDLKYYERSYAEGVRWADKATAILERLDAKEELANAYRIKANDQLFSTTNLEQAFASINKSIDLYAELGEYGIPMMASINWRGNIYKYMDRYDEAIAAYEANFDNSTKMGLERYLIPSLGNIGDVYSLQGKYKEALPYNLQAIDIMKKTGREKNLWENYMHVSNSYESLEDYALALFYHHLYAQAFEEFKDNTIHGLETEAQAKHETGQKNATIYFQDEKIAQQQRAKVLYIVLASLLAIIVFGLFYYYKKRQHKNNELRVLNSQLDTKNKQNELLLKEIHHPVKNNLELVKSLLALQSAKLEDSTTKDAMIASQNRVQSMGIIHQKLYQGENLGSIELKDYFLNLGKGSLDTFNAEDKVKIECAMENLELDVNTAVPIGLIVNELLTNTLKYAFPEDGKGNILISISQSTLETLTLKVADNGVGKVFGLAPKGTGFGTQLIQLLTQQLDGKMLEEHDNGTSVSFQFKTKPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-02-10" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEX1</accession>
    <name>A0A5C6ZEX1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GNAT family N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12725</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="147" mass="16994" checksum="C3DDA5D7C1B2289F" modified="2019-11-13" version="1">MLNITIKGFSELSTEALYEILQLRSEVFVVEQDCVYQDIDGKDQKALHVLGYEAKELVAYTRIFKPGDYFEKSSIGRVVVRQKKRKFNYGYQIMSASIEAVKTHYGETDIKISAQAYLKRFYNNLGFFEEGEGYLEDGIPHFAMFKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEY8</accession>
    <name>A0A5C6ZEY8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">N-formylglutamate amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_15890</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007709">
        <property type="entry name" value="N-FG_amidohydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05013">
        <property type="entry name" value="FGase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="260" mass="29824" checksum="E3807C5E10D1D9AB" modified="2019-11-13" version="1">MIGYHTLLGMNSFSDEIEDSYIFHIPHSKTEIPDKFKSDFVSAELMENEIKLLTDFATDEIFTIGSLSKVVFPYSRIFCDAERLDDENEVMFEYGRGFYETKTDSGELLRENSNGNKAMIHSDYYLKHHETLANLVDQKLKDNGFPLIVDCQSFAAIPFKSDIEQGGERPDFCIGTDEFHTPKWLVDMAVAFLTNQGYSVKINFPYVGTIVPLKHYQVNDDVQSIMIEINRKLYIDDGFVNDSKVSKLNQLMSNLFLVNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEZ2</accession>
    <name>A0A5C6ZEZ2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022773807" evidence="1">
        <location>
            <begin position="22"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="132" mass="14766" checksum="82E0FDC00F04DB89" modified="2019-11-13" version="1">MKSILTLLGVSVLLVSCQATADEPYQNFKSSDYEFIPEHNQDIHKVITFRNAQNEIVRIKPTTYNLEKAFVSGIAFSQPTQTASYYYDDLWIGLELLDVDVSNQVGGGCNQTPIHIHKVGDGSILTKMIIPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF03</accession>
    <name>A0A5C6ZF03_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">VWA domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="1">
        <location>
            <begin position="17"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="984" mass="110243" checksum="9B2E5FFFFFA414C4" modified="2019-11-13" version="1">MGIKAKAGQKNNACEAHIALAIDESGSISGSEIDQIKMGLKNFIASQLNNDNRISLVGMSNSDNDLRSDNIINQFVNDSTKSTFDNWILGFRSRSGAGIGSSSAHWSSALETIQSLQNPPDVVIIITDGLLVDTPAKLQNRIATVNSNSHIFVYGIDEINSYPNGNSLSQTLDFYLGRPAILSTDNSDILTTDYVTIPDFSGLENALSDLSQTLINSNIGCGNLDLISENITIGKLSLNCSNDDLNVGTITISSQKAVPYVIEADTQIANINGLIFSCAIATEIAPNGSGTIVPVKVNGTPFSVGFQEELIAIETVNNPENLKIEFCVVDRQTIKNGEVSAFIKSEYEYFLNLLCLLKQSKSDEEKGYTRNTLILQARNILRKLEETKPCGNITTVQEICWMTLENHEFNSTIPGQAEVEQEQKDMVAAVQKTVQPIWRPNTKYYMRFRLKDEVNNGEFEEQNKGLFDYYYGFKTVGPVGHYHKDSTVDYIPTDANPDQYPLTSLRQYIDYNRSYPNADGNLLQAKPLFYGNNQCKITVYFSKPFTYHMLNKWHSYEDSDSGNSLPELAGSMHIAIKDPVTDVIIPYPLPANFSQETVPTGQTFATWIEFNSQEELEFNECIRLIDVNDNPIGEYSILKKDYLIASDTYRLRIDDEAVLSDNSDLISGKIKWESLAADNPTVVYEFDIVAIGSEDANWNIDNNPRIPMNLQLLNNMVEYINQNNSAINCDLEIGEPILPNSYAYTVTLTNLKPRKLYTALLYNAFDKNNSGSLQDTESEEVHQFVFQTSRYKNFEEQVNSYWLRELDSDGIVVNEQQAVFIIPLSLSVDEIETAYNIVAGISDINSENLESQYYHLFDRATEGVLGISPFNPPENTEFNVLKNLNTGQTFGILIRNPEPFNIPKIPLDTIEDTVKVVFASSGNPNNTYKVLHSKDYSQVLIMHDSREITVDTLNFKFSYKIWNGSEYITSSDVVIDNILINIEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF91</accession>
    <name>A0A5C6ZF91_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Prenyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_15510</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="93"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="117"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="227"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="259"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD87872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="283" mass="32075" checksum="AA2FDAA9D9A18292" modified="2019-11-13" version="1">MKMTLKEIFLVSRPRFWMYVLGTFLVGVIASGNLFLYDATTTLLLIAFGLFFTLPANVFIYGINDIYDYQTDIHNDKKIKYESVLKQDKHRSLWLIIVLLLLPFLPLFFMVNLPAKLALLLFLFTGLFYSARPIRAKSKPPLDVLFSAVIYVTPALVGFFITGNTNIEWLAVLGGLIWAFGMQTYSAIPDIEADKKAGVNTLAIMLGEQKSFWFCLLAYVISASIGFYYVGFIAIVFGSVYSAMVLLSIYNSSKLFKYYTYFPLINVITGAVLFFYLFFKAIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFE0</accession>
    <name>A0A5C6ZFE0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SusD/RagB family nutrient-binding outer membrane lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_14795</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041662">
        <property type="entry name" value="SusD-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12771">
        <property type="entry name" value="SusD-like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022807467" evidence="1">
        <location>
            <begin position="23"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="528" mass="57997" checksum="7ED112254BEDF670" modified="2019-11-13" version="1">MKKIKFIGILTMIASLSLVSCGDEIEDVNINPNSPEVVPTNTIFNSATEQYFTNSRNEFNHGRFTLNWVEYWGQNSYADEDRYLYRETTVQSLYTAIYLVGTDLKSIIEINTDEATRVGASAVGNNNNQIAASRIILAYMFHQQTNTFGDVPYYSYGSDDPDFQALQIDEFLSPVFAPQEKIYADILKELRESADMINVNEPVFTSGDNIFNGDASKWKKLANSLILRVAANLREIDAATANTAIAAALADGVMTSNDDNAAQAYEDGDANANPIWKSFINRNDFAVSAPFVDLMKGTTGNFGPDPRLFSMAAPISASIPSIKAGDYTPSTDYADYVGVPYAYGNVNQLGFDLYSFPSSQVLKPSYAEILMEYAEVQFLISEYNGFAQVNYENAVAASMQKWGVPAADITAFVNNLPAANEANVLNQKYVALYMQGHQAYAEIRRTGYPNTSILFLPNETYTLSPAQAAATGESTYTFVSGVDGLTTLPFRVTYPATLQSLNGANRASAVSDLSDGDTVFSRLFWDVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFG9</accession>
    <name>A0A5C6ZFG9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ESY86_11565</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="34"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="265"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="290"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="36"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="352"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="385"/>
            <end position="392"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD88604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="590" mass="65267" checksum="F7FE6E025A122EFF" modified="2019-11-13" version="1">MQHLRDNSEDKNKSEPKVTMLQAFKTIIWPRRNLVFIGLILIVIKSLSGLILPWQSKVLLDDVVPNKDYGQLYTLIAIVISAITVQAVTSFLLTRILSVQAQYLISELRSQVQKKVLSLPIRFFDNTKSGALVSRIMNDVEGVRNLIGTGLVQLVGGTFTAVVSLIILIKLNAWMTLFVFVPLSIFGIIALKAFKYIRPIFRTRGKINAEVTGRLTETLAGVRVIKAFNAEEQENVVFEKGVDKLYQNVKKSLTATALMTSSSTFLIGVATTGIMGMGGYYMIIGEMTTGDFLFFTLILGFMIAPIIQMSNIGSQLTEALAGLDRTEELMNMTAEEENQNRTIKLNTLKGNIEFSDVSFSYEEGKQILHKLNFKVPAGSVTALVGSSGSGKSTIAGLSATFLTPQSGKVTVDNQDLSKVKLSSYRQYLGVVLQDEFLFEGSIRENIMFPRPNATEAEVQNAVNAAYVNEFTDRFDEGLETLIGERGVKLSGGQRQRLAIARAILANPKIIILDEATSNLDTQSEALIQKSLAELVKDRTTIVIAHRLSTIRKADQILVVEAGHIVERGTHDQLIAKEGRYYELYTYQAKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFL9</accession>
    <name>A0A5C6ZFL9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Prolyl oligopeptidase family serine peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_14170</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014940">
        <property type="entry name" value="BAAT_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08840">
        <property type="entry name" value="BAAT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="BAAT_C" evidence="2">
        <location>
            <begin position="113"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="287" mass="31848" checksum="5B1AC7FAEC9BE829" modified="2019-11-13" version="1">MKKRTKKILLLIALILITGIIYIFTYVPSLPKENGVVETKLYLGNSTNQPLIVAFGGGGGGNDWSRNYMKGKRDSLIQKGYAVLAIGYFNLNGTPQSLDRISLDAISDTIMNIAKNNKIDESKIALIGGSKGGELILNLASRFNQYKAVIAMSTSNVSFPAITWSANTSSWTYKGIEVPYVPAPLKTITPALKGDHFTAFNMMLEDEKAVKNAEIEVENINGPILLLSGKNDDQWPATSMSNKIIERLKKNNFKYFNEHIVLHGGHTEPLKHFDLIYEFLEKHLPAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFT5</accession>
    <name>A0A5C6ZFT5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="12">NADP-dependent malic enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">ESY86_14450</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the N-terminal section; belongs to the malic enzymes family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004471">
        <property type="term" value="F:malate dehydrogenase (decarboxylating) (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006108">
        <property type="term" value="P:malate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05311">
        <property type="entry name" value="NAD_bind_2_malic_enz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015884">
        <property type="entry name" value="Malic_enzyme_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012301">
        <property type="entry name" value="Malic_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037062">
        <property type="entry name" value="Malic_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012302">
        <property type="entry name" value="Malic_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045213">
        <property type="entry name" value="Malic_NAD-bd_bact_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012188">
        <property type="entry name" value="ME_PTA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042113">
        <property type="entry name" value="P_AcTrfase_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042112">
        <property type="entry name" value="P_AcTrfase_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002505">
        <property type="entry name" value="PTA_PTB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00390">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03949">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01515">
        <property type="entry name" value="PTA_PTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036684">
        <property type="entry name" value="ME_PTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01274">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00919">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00331">
        <property type="entry name" value="MALIC_ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="9" id="KW-0521">NADP</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="malic" evidence="11">
        <location>
            <begin position="19"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="Malic_M" evidence="10">
        <location>
            <begin position="164"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="77"/>
            <end position="84"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="287"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR036684-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR036684-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR036684-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TXD88115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="767" mass="84826" checksum="66F3B9F1FEA2569B" modified="2019-11-13" version="1">MSKQSRRREALVYHAKPTPGKIQVVPTKKYATQRDLSLAYSPGVAEPCLEIEKDKNNVYKYTAKGNLVAVISNGTAVLGLGNIGPEASKPVMEGKGLLFKIFADIDVFDIEVGTENVEEFIQTVKMIAPTFGGINLEDIKAPEAFEIERRLKEELDIPVMHDDQHGTAIISAAALLNALELADKKIEEVQIVISGAGAAAISCSRLYQACGATRKNMVMLDSKGVIRDDRDNLTAEKAEFATHRKIDTLDEAMKNADVFIGLSMADIVNPDMLLSMADDPIVFAMANPNPEIPYELAVATRKDIIMATGRSDTPNQVNNVLGFPFIFRGALDVRATKINEEMKMAAVFALANLAKEAVPEQVNIAYGETRLTFGRDYIIPKPFDPRLIVEVPPAVAKAAMESGVAKEPIEDWEKYRNELMERLGSDNKMIRLLINRAKMNPKRVVFAEADHLDVLKAAQIAHDEGIAIPVLLGRKDVILKLMEEIEFEADLEIIDPKSDEEEERKKKYAKVYWHQRKRKGVTLYSAEKLMRERNYFAATMVNEGDADALISGYARSYPSVVKPMLELIGLAPGATRVATTNVMMTQRGPMFLSDTSININPSASDLTKIAQMTASVVKMFGMEPVMAMISFSNFGSSKSQTADKVREAVAYLHKRHPDLVVDGELQTDFALNKDMLQATFPFSRLAGKKVNTLIFPNLESANITYKLLKELNKADSIGPIMMGMRKPVHILQLGASVDEIVNMTAIAVIDAQQKEQLEQKKLETSAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG57</accession>
    <name>A0A5C6ZG57_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Winged helix-turn-helix transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_13925</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019885">
        <property type="entry name" value="Tscrpt_reg_HTH_AsnC-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00033">
        <property type="entry name" value="HTHASNC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00519">
        <property type="entry name" value="HTH_ASNC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="4">
        <location>
            <begin position="10"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD88193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="156" mass="17622" checksum="6F9208FDD4A84AE3" modified="2019-11-13" version="1">MKVINQNIQIDGIDKKILRALMEDARTPILEIARNVGISGAAIHQRLRKLEKSGLISGSKFVINPKILGYTTMAFIGIHLDKAMSNPEAVKQLQKIPEVLECHYTTGNWSIFIKILCKDNEHLMQVLNKDIQSITGVSRTETFISLNQQIDRQIKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG68</accession>
    <name>A0A5C6ZG68_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA pseudouridine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140098">
        <property type="term" value="F:catalytic activity, acting on RNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034470">
        <property type="term" value="P:ncRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02869">
        <property type="entry name" value="PseudoU_synth_RluA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluC/D_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PseudoU_synth_2" evidence="1">
        <location>
            <begin position="14"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="228" mass="26048" checksum="B4D8811ABBB17D01" modified="2019-11-13" version="1">MPSPNLELIHENNDYLVVNKSAGLISEKSLYEKSTVEDQVHQHLSKNNRKPYVGVIHRLDRVTSGVMVFAKKKSILVQFNELFSSRKVQKTYLAIVKKKPAKTKAHLTNFLVKNNLEKKADIVPSKSKTALECRLSYQVIDENEFGYLLEVKPTTGRFHQIRAQLAHIGLPIVGDEKYGSDQKYVPLSVCLHAWKLSYQVSGSKAFETFEAPVPKNAFWRFKSFEKQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG75</accession>
    <name>A0A5C6ZG75_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_09925</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="12"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="74" mass="8022" checksum="E0373EC26316AD07" modified="2019-11-13" version="1">MQVKFYFTTYFSTSTSTSTSSSSSSSSSSSSSSSSPISRLPSPVSLFSPLFSALIREICGISQGSHYSSRRFRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGF1</accession>
    <name>A0A5C6ZGF1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha-amlyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10265</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043169">
        <property type="term" value="F:cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006048">
        <property type="entry name" value="A-amylase/branching_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02806">
        <property type="entry name" value="Alpha-amylase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aamy" evidence="1">
        <location>
            <begin position="34"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="445" mass="52090" checksum="7E461358A738A175" modified="2019-11-13" version="1">MEKPHAMEPTNPHQPQEYVKLQHPEWSKNASIYQLNTRQFTKEGTFMAAQEQLPRLKALGADIIWLMPIHSIGEKNRKGALGSPYSIKDYYSVNPEFGDLQDLKNFVNAAHKQGMYVILDWVANHTAWDNDLVNEHPDWYERDYKGDFRPTPWWDWSDIIDLDFSKPELRNYMTEALKYWVKEANIDGYRCDVAGFVPVEFWNHARKELEAIKPVFMLAEWESRDLHAEAFDMTYAWSWNEAVHRICTGKADVNALYIYYSWNESAFPKNSMRMTFVSNHDKNAWEGTMYEQFGNGLEAAIALSVVGEGMPLIYNGQEAGNDKRLAFFEKDPIVWKQDEIGDLYKELFKLMHTNTALWHAKWGSTMIKVPNNTEHAVFSFVRQNEDDKVFAVFNFSDKTQTITFKEPLFVGDYSEFGTTENKRFAENTSLELKAWEYRIYVKKPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGH6</accession>
    <name>A0A5C6ZGH6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_09110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018641">
        <property type="entry name" value="Trfase_1_rSAM/selenodom_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36529">
        <property type="entry name" value="PTHR36529"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09837">
        <property type="entry name" value="DUF2064"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04282">
        <property type="entry name" value="glyco_like_cofC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="223" mass="25496" checksum="74DA289F41EBB0D4" modified="2019-11-13" version="1">MGILSNNDIKNDHELMANFHFPTSKKALIVFTRNPELGKCKTRLAKSIGDESALKVYKHLLQHTANVAKKVSADRFVFYSEHINNSDIWDEAFFRKKLQEGNNLGEKMHNAFSLLFASGYEKVCIIGSDLLDLDAEIIDEALETLNHHDVVIGPAEDGGYYLLAMNEMQRPVFENKDWGTETVRNATLENLADKKVHLLKALNDIDTFDDMKHYDELKKFYTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGN8</accession>
    <name>A0A5C6ZGN8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_09590</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="120" mass="14014" checksum="CD4984B971F741F9" modified="2019-11-13" version="1">MNSPSDYAEGDVGTFSNDFYDFCNLDFSNISNAKYEAYSEFVWETANGNQHADNQPDLFQFSFFGHTGRFIILNINGALQPKIISSDQKVINIKRLIYVYKLKYPLFFEKQFSLLQIYYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGV5</accession>
    <name>A0A5C6ZGV5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Succinate dehydrogenase cytochrome b subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011138">
        <property type="entry name" value="Cytochrome_b-558"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034804">
        <property type="entry name" value="SQR/QFR_C/D"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81343">
        <property type="entry name" value="SSF81343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02046">
        <property type="entry name" value="sdhC_b558_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="228" mass="26101" checksum="0D1BC7EF0368E026" modified="2019-11-13" version="1">MSGILNSSIGRKFAMALSALFLMIFILQHFSINILSVFSPDTFNNVSHFMGTFWLVQFVLQPILILGVLFHFIMGFVLEIRNNRARQKSYIKDNGNAKSTWMSRNMIWSGGFILIFLIIHFIDFWIPEINTKYIVGDASGLQDPNNIDSGFRYYEELVHKFEPLWRVALYCVGFIFLALHLLHGFSSSFQSIGANNKYTRGLKGFGKVYAVGIPLGFIFIAVYHHLSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHE6</accession>
    <name>A0A5C6ZHE6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_10215</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="175" mass="19917" checksum="49CAF0F501B0D4D9" modified="2019-11-13" version="1">MQLLGIGSRINHSDFGKGVVTNITSKHYWVTFMENGLETIDIDSDFEVIEACEDEVDSVSFAEVESSLVQILKRWSDVSEVVPIADKWKGGKLILEPGEAGLQAKELPIDSFFHKITMVRDRLRVMEQKINASKNLDEQEKIDLQQYLTRSYGSLTSFNVLFKLKNQQFVGQKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHE7</accession>
    <name>A0A5C6ZHE7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11185</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="230"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="260" mass="29538" checksum="5631C3662BC2C29D" modified="2019-11-13" version="1">MLKILKYSFYDLMRSRWSYVYFAFYLLLGIVLLFLNNDLSKAVITLMNVIIVLVPLIGTIFGVMYYYNSKEFTELLLAQPLKRSSIFMGQYLGVAISLSMSLILGLGLPFVFYGLFESSAIWDFSLLLITGTFLTLIFTALAFNIALSNENKIKGFGYAILLWLFLAVIYDGLFLMTLIMFEDYPLDKLSLIGTMLNPIDLSRTLILLKLDISALLGYTGAVFKQFFGTSFGLIVSFAMLTVWVILPVLRIIFKSNKKDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHG4</accession>
    <name>A0A5C6ZHG4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_10325</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HAM1 NTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047429">
        <property type="term" value="F:nucleoside-triphosphate diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009143">
        <property type="term" value="P:nucleoside triphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002637">
        <property type="entry name" value="Ham1p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11067">
        <property type="entry name" value="PTHR11067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01725">
        <property type="entry name" value="Ham1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
        <property type="entry name" value="SSF52972"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="101" mass="11190" checksum="B7646439049958C5" modified="2019-11-13" version="1">MSAETSRNYTAVDELIVPADFADGRRKRIALYRSGKTKPFTGICKGAITTAKRGKDGFGYDPIFKAEGFEQTFAEISLDEKNEVGHRGKAVRQLVAYLTKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHI2</accession>
    <name>A0A5C6ZHI2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GNAT family N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038740">
        <property type="entry name" value="BioF2-like_GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13480">
        <property type="entry name" value="Acetyltransf_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Acetyltransf_6" evidence="1">
        <location>
            <begin position="201"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="386" mass="44714" checksum="712491CB84059947" modified="2019-11-13" version="1">MIHFKIYNSVENLPKEWNAFSTEDIFLKTPFLKALEHASPANISSYYVGVFSAEGLVGLAIVQRVELYAQDIFRKSQKLWYKQLGKDLVAKIAKGNALVVGNLMHTGQHGLSFASEAISQRDFLETITKAIAQLSADIKLQFGKKIRIIAFKDYFENDTLHASTDFFRSQKLYKVQMQPNMILNIPEHWKSTNEYTAVFNKKYRRRYATARKKADPIISKELNLVEIENHKEAIYGLYESVSDNAGVNSFKLPKTHFYELKKQLGIKFKLFGHFMDERLVGFYSLILNGNHLETYFLGYDQNLQHKHQMYLNMLYDMAFFGIEQGFESVIFARTAMEIKSSVGAKPYAMAVYIKHSNTFLANRILKLIVTYMNPVQVWEERHPFKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHJ3</accession>
    <name>A0A5C6ZHJ3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_09135</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="216" mass="24824" checksum="A5FA8686FAC49724" modified="2019-11-13" version="1">MKKIGLLFNGVWSHYTFATAPKYKDLIELIYIHDFDETSLDRLEALMIPFQSNQNAIAKRKDVIYDFLAKGKKVFIEGDSSMDWIEAKWEDRPTNNYWWVENPNNPPISDTDFTHPIYEGLTPRQSCWHTHGSYTSMPSQAKAIQKKPDGEIISWETQQYGGTLFATTLDPIVEHGVQQITHLDHYVDKLIFWLSGDKASGSFDVPRENYGIAVSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHS3</accession>
    <name>A0A5C6ZHS3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Zeta toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_09340</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="174" mass="20166" checksum="CA63107175E6D60A" modified="2019-11-13" version="1">MRPAKNIYIIAGCNGAGKTTASYTILPEIINCKEFVNADEIAKGLSPFQPETFAFETTLSTKSYKNKILKAKQQGYMVTLLFFWLNNIDLAKERVKTRVFEGGHNIPEKIIERRYLRGIHNLFDIYLPLMHAALVFDNSFGKHELIAHKMTEDDLIIYDQDKFQQLKRIHDNKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHU3</accession>
    <name>A0A5C6ZHU3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_09575</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="141" mass="16682" checksum="D7A598E2D2AA108C" modified="2019-11-13" version="1">MIVVLILTTIVVGLAFSVLILVQRQMLAIQGNYQTNLELNTLETSLWLDFNRYSKITYDELEDELKFSTELDSISYRFYDKRIIKDRDTFSVHIKQKIFFLDAEEKEKGNIDAMKLEMPDSYQNKKLFVFKTNDAKLYMNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHY0</accession>
    <name>A0A5C6ZHY0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glyoxalase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_10545</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="137" mass="15726" checksum="B1966E0FC6386226" modified="2019-11-13" version="1">MTERSKNLLAIRPDIASAKLTEGMSDDERFQNATLRPIIKLQNDLLVAVFGNYIVKHKNVFYEQSLPKQLAYIENAINKDMKFRNSLKGMIIGQFSAEEYAVYIKNSSALNKRMMQIVKERLISNVQLFSLPLTEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI88</accession>
    <name>A0A5C6ZI88_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF3575 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_08435</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="178" mass="20103" checksum="F3AE410EDAA1F934" modified="2019-11-13" version="1">MLSLALVTLAFAQNDSLQDPYKKDNEIKINALFLLLGAIEPSYERNLSESSSVGISMLITYDQENFDSDLNYYLSPYYRMFFGKKHAAGFFLEGFGMVISYDERQRYFTGSEFDPRLVIEEKNITNVALGFGLGGKWVTKDGFVFELNAGLGRNLINNSDSDVNQLVGKLGFNCGYRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIA8</accession>
    <name>A0A5C6ZIA8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">GLPGLI family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_07590</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005901">
        <property type="entry name" value="GLPGLI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09697">
        <property type="entry name" value="Porph_ging"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01200">
        <property type="entry name" value="GLPGLI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="241" mass="27811" checksum="214A8A6EA74EC6CA" modified="2019-11-13" version="1">MKHLLIIIIILLNYPLSAQVKSGFLTYGESIVHAPVDTSKIKDRQVKEIIAQQNSAIEQALSSDSDLYELSFNRQEANFQVIPFVENDINPYLKRAVSPGIYYSNLKEDFKLHQLFAYDDYYLIRQNANVYVWNISKEKKKIGDYTCYKATTTIENGRTIKTEITAWFTPEIPFRFGPKNYGGLPGLILALEERGHYFYAKKIVLKQEEKKVKIPHKGKQVSQTEFTEIGRAVMKQMKGED</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIB2</accession>
    <name>A0A5C6ZIB2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">LPS export ABC transporter periplasmic protein LptC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">lptC</name>
        <name evidence="7" type="ORF">ESY86_09250</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015221">
        <property type="term" value="F:lipopolysaccharide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010664">
        <property type="entry name" value="LipoPS_assembly_LptC-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026265">
        <property type="entry name" value="LptC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06835">
        <property type="entry name" value="LptC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04409">
        <property type="entry name" value="LptC_YrbK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD89224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="189" mass="21446" checksum="598C37E646CE1920" modified="2019-11-13" version="1">MKKSCLYFNTCIVTTFVVTMLFSCKNNFKEVQQIGVLQNQPIGVAKNINLKYTEAEDSIGRLIANLKSPKMLDYSNREFAFQEFPEGVVLSLFDEKGQKNVVLADYAIVYGETDLIDMQGNVILITPQKDSLFAEQMYYDQKQEWLFSNLPVSLKSATSNSGHGDIFDSDTKFKNYTILEGRGDMIVKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIJ7</accession>
    <name>A0A5C6ZIJ7_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Endolytic murein transglycosylase</fullName>
            <ecNumber evidence="7">4.2.2.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Peptidoglycan polymerization terminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 8" type="primary">mltG</name>
        <name evidence="8" type="ORF">ESY86_11060</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the transglycosylase MltG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.2.-" evidence="7"/>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008932">
        <property type="term" value="F:lytic endotransglycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd08010">
        <property type="entry name" value="MltG_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02065">
        <property type="entry name" value="MltG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003770">
        <property type="entry name" value="MLTG-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30518">
        <property type="entry name" value="PTHR30518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02618">
        <property type="entry name" value="YceG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00247">
        <property type="entry name" value="TIGR00247"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="5 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="7">
        <location>
            <position position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD88773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="347" mass="39362" checksum="90372E4382B7E877" modified="2019-11-13" version="1">MYIKKILWVIAIIGLVGAGIFAYYIYNAMLSPNTAFDNEDAYIFVPTDANYAEVREQLQPLLKDIGSFDAVAKQKKYTTNLKSGRFVIKKGMSNNDIINSIRSKNLPITIAFNNQENLAKLAGRISGQIEADSLSLISAMTDPEFLKASGFNKQTALGMYIPNSYEFFWNSSAETFRNRMLKEYNRFWNDARKAKAESIGLTRDQVLTLASIVHEESKQASEQPRIAGVYMNRIRIGMPLQADPTLKYAAYQLPKYQNTVIKRVLNVHKDIESPYNTYMNRGLPPGLIAMPDITAIDAVLNFEKHSYLYFAANANKMGFHKFAKTLAQHNVNAREYQRYLSNQGINK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIR5</accession>
    <name>A0A5C6ZIR5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Carboxypeptidase-like regulatory domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_07570</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="902" mass="103416" checksum="1DC8755B08383F21" modified="2019-11-13" version="1">MKLDKETKNLANVLGRLVLIILPFLSLNSQNIVVSGQITDTLQTPLSYANILAIPDADDQEVRFAITEADGSYKLGLAKNQSYKVTVSYLGYSSQILEITTTEEDIIKSFILQENPDQLNEVELNYTPPISVKKDTITYNVDSFKTGEERKLRDVLKKLPGVEVDRDGNVTVQGKKVTKVLVENKTFFTGDSKLAVNNIPADAVDQVVVLDNYNEVAMLKGLQDSDDMAMNIKLKEDKKKFAFGDVEVGAGIKDRYLIHPNLFYYSPKTNINFIGDLNNRGVKSFTFRDYLEFEGGFGKLLEDTGNYFSLYNSDFAQYLNNQDFKSNTNQFGALNIRQAINSKTDISGYIITSNSKTETESSTLNEYLNFTEPFVEERNINNTLRNFFTIAKITLDYDPSYDEDLAYNSFVKLSNNDSNGLIATINPTQSNRINTRTDVTGINLKQNLSYSRKLSTNHTATLEATYEFQNDKPLTEWLTNRQILQGLIPLEDDVVYNILQTKHSNAHNVNAIVKDYWVLNNFNHLYASVGVNAAFTHFENQDVQLLSDGSVNNFSSAGFGNDFGYDFINTFVGFEYKFQIGIATFKPMLYYNFYKWNTKQFDERFSNQKALLLPKFTTKVEFNNSEKLNFRYQLNARFPSIDRLANNFVLSSFNSVFKGDTTLDNQLYHSVNLSYYKFSLFKNLNFNINSSYNKKIKSFKTVTQLQGIEQFSTAILFDRPEQSWMLSSRFSKKIKKLKYNFSARYSYTDFYQLLNGQTNLNISKSLSSTLSIETSFKEHPNVEVGYTKDFNNYRAFGAPNNFENDRFFINLDYDFLENFILKADYSFDAYNNKSANIKNTFDTANASLFYQLEDSPWGFEINASNLFDVGFKQQNNFNSFVISDSKTFILPRIIMFKLAYKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIZ7</accession>
    <name>A0A5C6ZIZ7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Mechanosensitive ion channel family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_10915</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045275">
        <property type="entry name" value="MscS_archaea/bacteria_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011066">
        <property type="entry name" value="MscS_channel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011014">
        <property type="entry name" value="MscS_channel_TM-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30221">
        <property type="entry name" value="PTHR30221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82689">
        <property type="entry name" value="SSF82689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82861">
        <property type="entry name" value="SSF82861"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD88992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="305" mass="33976" checksum="CADF9B0C557FB73F" modified="2019-11-13" version="1">MIASDTSFLSESFTYFFDQLVAQLPKIALAVLIVVLGVLIASWLGQFARRRISAKTHDPLMSKFLGQSIKYILIIISVMIGLRAAGLGGIATGVLTAAGAGAVVLGFAFKDIGENFIAGIILAFNRPFNVNDTVEIGENFGKVKTMEFRYTKLKTFDGKDVYIPNSDVLTKPVTNYTEDGFFRWDFIIGIAYEDNIEGAKKTVMEALRKIPNVIEDAEHENFVIEDQLATSTVNLKVFFWVDTMDFRRMALITKGNVVRNVKEALEDNGYYMPADIQEIKLYGGQKEFPVRLAKDIVESDPKPKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ27</accession>
    <name>A0A5C6ZJ27_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UDP-N-acetylglucosamine 2-epimerase (Non-hydrolyzing)</fullName>
            <ecNumber evidence="3">5.1.3.14</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_09740</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UDP-N-acetylglucosamine 2-epimerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.14" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008761">
        <property type="term" value="F:UDP-N-acetylglucosamine 2-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003331">
        <property type="entry name" value="UDP_GlcNAc_Epimerase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029767">
        <property type="entry name" value="WecB-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43174">
        <property type="entry name" value="PTHR43174"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02350">
        <property type="entry name" value="Epimerase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00236">
        <property type="entry name" value="wecB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase_2" evidence="2">
        <location>
            <begin position="33"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="368" mass="41497" checksum="8A5EF479910078AB" modified="2019-11-13" version="1">MITMKKKLLLVVGTRPNYIKVTQFKTVAERDFENQFEIKIVHTGQHFDKAMADDFFKQLDLWPDYFLNISQGSANTQMGEIMLRLEGVISEFKPDMLIVPGDVNSTLAAALTANKLGIPLAHLESGLRSFDRSMPEEINRILVDEISDHFFVTEQSGIDNLVAEGKPKERVHFVGNTMIDTLVAFETEIAAQPILDQYQLKPNGFILVTIHRPATVDHEDGLKTLADLLENLPSEQKIVFPMHPRTRKHIAKFGLTERFDQLEQLIIVEALDYFSFQSLIHNCSLVLTDSGGIQEETTFKQKPCLTLRPNTERPSTVTIGSNTLLNLDKDKIVAHIDSILNGNYKKGKVPELWDGKATKRILSVIADL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJA3</accession>
    <name>A0A5C6ZJA3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022816835" evidence="1">
        <location>
            <begin position="20"/>
            <end position="580"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="580" mass="60706" checksum="C067A421CA55A18A" modified="2019-11-13" version="1">MKQKLLFLTLFVLSTFTFAQSPEGFTYQAVVRNSADELTSNANIGMRLSILQGTETGTSVYTETQLTSSNSNGLISLIIGNGTVVSGSMSAIDWSNGPYFIKTETDPTGGNNYTIVGVSQMLSVPYALYAANSATGAEGPQGPAGPIAGTNTQITFNNEGNAAGSANLTWDDATNTHSVNGTSITTNGKVTGLAGTGTRPVAVDENGNFVIGSATGGSGISGTGNNNFHLKWTTAGAVAGNSMIQDNGTAVAVNSSPNQKYLMYVYKNQLTNEGDGQHSLIGWRTRNSPNEGTGYSLTKTNTGTAGNSFWGDKYSFGVGGWNFNDFTRTGGVLGADNGGNYWGALGYRTSASLTYGVYGSNAYGAGAGFLPNTEISGFGGGFFGMIGSASKGSLIGQLNAGDLFSSYNSGNLYTLGKNVELVATANNKVTPVYAVTSVESTIYAKGNAKLVNGEARILFDEQFKSLLGESPEVTVTPKGNCNGVYIASIDRNGFSIKEMDNGSSNVDVSWISVGNRIDNGMDKATKKVTDPSFERNIQQVLFNDGNTDAKGQGIWWDGANIRFGNMPAHLTKVERPKGAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJC1</accession>
    <name>A0A5C6ZJC1_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dipeptidyl-peptidase</fullName>
            <ecNumber evidence="4">3.4.14.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_08500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the removal of dipeptides from the N-terminus of oligopeptides.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the peptidase S46 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.14.-" evidence="4"/>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070009">
        <property type="term" value="F:serine-type aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043171">
        <property type="term" value="P:peptide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019500">
        <property type="entry name" value="Pep_S46"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38469">
        <property type="entry name" value="PTHR38469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10459">
        <property type="entry name" value="Peptidase_S46"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0720">Serine protease</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU366067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD89414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="695" mass="79254" checksum="C60CE4F8D8972EAD" modified="2019-11-13" version="1">MRFLKVIFFFIVVQVSAQQGGMWIPSLLQGMNEDEMQSLGSKLTAQDIYDVNNSSLKDAIGHFNGGCTSEVISPKGLLLTNHHCGFSQIQSHSTLENDYLKDGFWAMSMEEEIPNEGLFVEFIVRIEDVTEAMLAGVTDDLEPRERQSKIDINRNAVVKALNKEDWQDFKIRPFYQGNQYYLFVTERFEDVRLVGAPPSSIGKFGSDTDNWVWPRHTGDFSMFRIYANKDNRPATYSKDNVPYTPKHFLPISLDGIEEGDFTMVFGFPGRTSEYLPAVAIEQITQKVNPSNIAIREAALKVIDANMKVDDQIRIQYASKQARIANAWKKWIGENLGIEKSGAVAIKREFESEFTKALKAQNKEAQYGNLLPEFERLYSEFESVNVRRNNFIEVFLRTNELMQMTFRAYQMEQALQADPDKFETAKSQMENTLKGIHKNYSAKVDQGVFEAVMPLYSKNIPSGIYKKSAFTDLDSALKLLKGDKATVLKNLNDDVAYKYAKPMIAEFYNSLEPEFQRINTQINTLETQYMKALMEVMPEERYFPDANGTLRVTYGKVNGYAPRDAVQYEPVTYLEGVIEKYIPGDYEFDVPEKLLDLYKAKDYGQYADENGKLPICFLGTNHTTGGNSGSPAIDAEGNLVGLNFDRVWEGTMSDIYYDPEICRNIMVDLRYVLFIVDKYAGAKHLIDEMTLVHPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJL1</accession>
    <name>A0A5C6ZJL1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dihydroorotase</fullName>
            <ecNumber evidence="2">3.5.2.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.3" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004151">
        <property type="term" value="F:dihydroorotase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="1">
        <location>
            <begin position="52"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="450" mass="51261" checksum="0D5ABE834DCFE126" modified="2019-11-13" version="1">MKERFLIKNTTIVNEGESFIADVLLADGHIQQIGTIDVEPNYKVIDGTCKHLLPGIIDAQVHFRDPGLTHKGDLYTESRAAIAGGVTSFIDMPNTVPNILTVESLKEKYEIASKKSLANYAFFLGVNGDNIDAVIKMDTSQFIGVSDDGLYFTKKGNLLADNPETMEKLFANCKSIIAIHSEKEQIVEENERIFREKYGEDIPAKFHPIIRNTEGCYEATKRAINLAKKHNARLHILHLTTEAETHLFQNDIPLQEKKITTEVSVHHLWFSDKDYEQLGMLIKWNPAIKTQQDKEGLLAALLNDRIDIITTDHAPHTLEEKQKTYFQSMSGAPMVQHSLNCMLEFYKEDRISLEKIVEKMCHNPAILYGMTKRGFIREGYYADLTLVDLNSKWTVEKDNLLYKCGWSPLEGTTFQTEIKQTFVNGNLIYDNGVFQENIFGMPIVFNNKQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJT2</accession>
    <name>A0A5C6ZJT2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Alpha/beta hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_05605</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000801">
        <property type="entry name" value="Esterase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00756">
        <property type="entry name" value="Esterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="433" mass="49364" checksum="B2C3C5F732848596" modified="2019-11-13" version="1">MELKIRIREINFFITINTQLMKLKSLSLFTLIVLCYTVSIAQSKQLINIGQSNTIYSKILKEERTIWVQVPESVNAKTNHPNKYPVVYVLDGGVHFLSVCSVINQLSPSSVPEMIVVGIGNSENRTRDLSPTKVKEARGSSEWVKDSGGGERFTDFIAQELIPYIDNTYPTANNKTFIGHSFGGLLVVNTLINRPELFNNYIAIDPSLWWDNEVLTGKIADRLPSEKYKNKSLFLSMANPLPQDTEKDINVLIKDNSMSTEGLRAIHRFSKTVSEATNSSLDFNYKYYENEDHGTIPLISIYDGMRFLFPWYKMSGKLVDIIKNPNTTAEKLKNAFNTRFDMLSNNLGYQVYPEEEMLNNLGYMFMSNSPKKSFGLLEMAIKYYPKNANGYDSMSDYYVSQNDFQNAILYSEKALAISGSDYHKNKLQKLKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJU1</accession>
    <name>A0A5C6ZJU1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Gliding motility lipoprotein GldK</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">gldK</name>
        <name evidence="2" type="ORF">ESY86_05675</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1580.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019866">
        <property type="entry name" value="Glid_motil-assoc_lipo_GldK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005532">
        <property type="entry name" value="SUMF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042095">
        <property type="entry name" value="SUMF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03781">
        <property type="entry name" value="FGE-sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="SSF56436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03525">
        <property type="entry name" value="GldK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FGE-sulfatase" evidence="1">
        <location>
            <begin position="42"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="456" mass="52141" checksum="1CCC30D4A759ECDF" modified="2019-11-13" version="1">MNFKKFALLTAVLALLVGCNSGDRGQLVGVKGKKWHPEKPYGMTLVPGGAFIMGKSDDDLPGVQDAPTKTVTVRAFYMDETEITNSEYRQFVEWVRDSTLRLKLAILADDIGETPGNGGIGEFAFMDADPANMTVYEQYMYDNYAGLGPTGYESRKLNRDIQLVFDTADYPDEYYAEVMDTMYLPIEESYNGQRTWDVDKFKFQYTYMDIKKAVKDRSLKRSDVLVTEEVKVYPDTTAWIRDFSYSYNEPMHNDYFWHDAYSNYPVVGVSWKQANAFCQWRTLYHNADRKKRGKHNVNTYRLPSEAEWEYAARGGLQGATFPWGGPYIKNDRGCFMANFKPLRGDYAADAALYTVEADSYEPNDFNLYNMAGNVSEWVQGSYDAASYEYMATFNPTVNDPDNERKVVRGGSWKDVAYFLQVSSRDYEYADSARSYIGFRTVQDYLGTEVTKNAATN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJU6</accession>
    <name>A0A5C6ZJU6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_08080</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011623">
        <property type="entry name" value="7TMR_DISM_rcpt_extracell_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011622">
        <property type="entry name" value="7TMR_DISM_rcpt_extracell_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07695">
        <property type="entry name" value="7TMR-DISM_7TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07696">
        <property type="entry name" value="7TMR-DISMED2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="187"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="215"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="252"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="283"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="307"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="340"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="423"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="5">
        <location>
            <begin position="665"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="715"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD89340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="793" mass="89444" checksum="9E006FDA51FFB9F1" modified="2019-11-13" version="1">MLLIAPNMKLPLLIIYFIGLGLYAQDVPYNPQTSKGELYEYAQFADAGKVNLSISEVLSAPNIAYNNLESENHSVGFTGDNYWVRFSLENSDETQKTYYLETARPITDLATMFQISETGIIIGKSGDQIPFDERQVKHRSTIFKISIPAKTTTQIYLHLGSDGETINIPLNLYDEVSFWMVNYKQQLFLGLFYGLLLLAGTIYLFFFTSLREKTFLYYGLYVFSIGLMQAALDGFIHQYILSDGGFINSRAVMIAAILSNFFLLKYSEYFLKVDTSLPNFKKAYNTIYAVLAILFIMIFIGPKSLELVYPISNINGLLSLILILTTVFTMRYKRMAIDPYFSFGIFFLVIGLLGFVLNNLSLLPNNFFTLNSAKFGSAFEVIFLSLSMTNLIRNLRLEKEAIQDEALQKSEEISQLKSYFMSNISHELRTPINAIMGVAELELKDQNNSVENRKQYQVIKNASLSLLSNVNDILDFEKIEKNELVLELDEFNPSVMIHQISSNWKIEAEGKGLDYTFDMDHDIPTTVVGDAERFMQILNNVLGNAVKFTNDGHVTFKLKCTAQPKSVSRFSMQISDSGVGMDREQKKNVFDSFNQMRLNHKRQFGGIGLGLSIVRHLVGLFDGEIYLESETGKGTDVFIELPLKSLSKSETALNDIQKLTVKPQHILVVEDNKLNQMVMRKLLSGLPHISFAVVNNGQEAIDALQKEVYDLVLMDLQMPVMDGYEATEVIRSGKLGKAIGSIPIIAVTADAMQETRKKVLDTGMNDYMTKPVSKELLLQKIGKCQVNPILKIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJV5</accession>
    <name>A0A5C6ZJV5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SDR family oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06470</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="267" mass="29613" checksum="6C3F17736F609452" modified="2019-11-13" version="1">MSKVVLITGGSSGIGKSIGEFLSDKGFVVYGTSRNPERYADSKFKLVKLDLSNTDSISQSVNHILETEGRLDVLINNAGAGITGPIEEIPEAEIKRNFETNLFGPIKVIKAVLPHMRSQNNGMIINVTSIAGYMGLPYRGVYSASKGALELITEAFRMEIKSFNIHMCNVAPGDFATNIAAGRYHAPVTEGSPYQKSYGNALELMNAHVDQGENPELMARAVYQIIQTRHPKIHYKIGNFMQKFSIVLKRTLPDKIYEKMLMKHFEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK13</accession>
    <name>A0A5C6ZK13_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="15"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="66"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="128" mass="15601" checksum="1EF9A09B2D988C6E" modified="2019-11-13" version="1">MATKVLYNENMHFEHQQWKGELDFWKDELKSFNNRLSELVTRWTDKKILEQLEHYQNEFILHGSVIEDLNETIEKHETRIAGQSKTGSDALDTQMTKQHVEFRNRIETQRQIYAELKEEFFKFLEKYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK73</accession>
    <name>A0A5C6ZK73_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_01800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="502" mass="59223" checksum="2E3D94EAF2EE7DCE" modified="2019-11-13" version="1">MTDLSAIIATFSSEDLQHFTTYLEKKNKRRDTKNIELFRLLAEDKLSSNAICERLYKDNNKVAYHALRKRLYQSLIDFIANRNLEEENSVDMQIIKYILAARTFLTHKESKMAYQVLDKAEMLAQEHQLFPILNEIYHTQIQYAYLEPSADLAALISKFRSNQKHQFIEEELNLVYAKIRQTLNAMVYRGAVLDFETILKDALTEHHIDISEALSFKSLYQLMTIVSLSAFVTNDYLKIESFLLDTYDKLKDHKTKDKQLFYHIQVVYIIANTLFRNKKFSASLQFLEQMKSLMLKNRKKHFNSFKPKYDLLTALNLNYSNRPEEAISLLNAVKDTKHADSESLLDINLALVMFYMQSTDLKKAKHLFSKFYHTDKYYSEKAGQEWTIKKNLAEIILFMEMGELDLVESRLRSFKRSFYPYLKAIDQERVITYLNLIAAYYKEPEKVRSKAFANKLEQSFDWVDSRQEDIFVMSFYAWLKSKMESRPLYETTLDLVKSAQLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKE1</accession>
    <name>A0A5C6ZKE1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cation-translocating P-type ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_03620</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="223"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="252"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="629"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="660"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="699"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="738"/>
            <end position="760"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="772"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="806"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="domain" description="Cation_ATPase_N" evidence="8">
        <location>
            <begin position="2"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD90466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="835" mass="92033" checksum="33B798C6A7B31025" modified="2019-11-13" version="1">MSLKNIDIQGLNQEQVLASRAKHGSNILKSKKKNHFLEAIKGLAKEPMVILLLVAASLYFFTGNTGDGLFLSAAILLVAAISLYQDAKTHNALEKLKDLSQPHCKVIRNGTVEEIKSEAVVVGDFLMVEEGSTIVADGTIVHSNDFSVSESILTGESFSVEKEATSKDNQIYMGTQVAGGLAIAEIFAIGNQTKMGKIGKSIEDISSEKTTLELQINNFVKKMVIAGTLVFLVVWGINYYNSENVLDSLLKALTLAMSILPEEIPVAFATFMAIGAWRLMNMGVIVKQMKTVESLGSSTVICVDKTGTITENKMRLDKMFTLETNKSTPVVALLSDSEKALITTAMWASEPIPFDTMEQSLHHFYETSIETDERPNFKMVHEYSLGGKPPMMTHIFENASGNRIIAAKGAPEALIAVSQLSDSQKAHLKERIGELASEGYRVLGVGLTNFEGQNWPKKQQDFHFEFKGLVAFYDPPKENITQVFQDFYNAGIQVKIITGDIAETTAAIAKKVNFIGSEDVVSGDELMSLNASELQKITSEKNIFARMFPEAKLKIINALKAQGHIVAMTGDGVNDGPALKAAHIGVAMGKKGTEIAKQSASLVLVDDDLSKMVDAVAMGRKIYFNLKKAIQYIISIHIPIILAVFIPLVLGWVYPNIFTPIHVILLELIMGPTCSIVYENEPLEKNSMLQKPRPFSSTFFNWSELFTSIIQGLAITIGVLAVYQIAVNNLQNEAITRTMVFTALISANIVLTLVNRSFIYSIFTTFKYKNRLVPIMIGITVSITLALLFIPPFTEFFGFERLSIEQIGISVGIGMLSTLWYEIVKWWKRQQLAKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKK7</accession>
    <name>A0A5C6ZKK7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4290 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025632">
        <property type="entry name" value="DUF4290"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14123">
        <property type="entry name" value="DUF4290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="184"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="219" mass="25992" checksum="1101C891A730EB83" modified="2019-11-13" version="1">MLTDNLEYNTEREHLIIPEYGRHLQKMINYAKEQPTKEERLKVANAIISVMGNLQPHLRDVPDFQHKLWDQLFMMADFDLDVDLDFPKPTREEVYARPEPLEYPQNFPKYRFYGNNIKTMIDVANTWEDGELKEALIYTIANHMKKCFLNWNKDTVEDDVIFKHLYELSDGKINLNKEEEDLSDASSLMRGNTKYTNTKTSSKKAHHKKNTSNRSRKRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKM4</accession>
    <name>A0A5C6ZKM4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06815</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022735715" evidence="1">
        <location>
            <begin position="20"/>
            <end position="495"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="495" mass="52356" checksum="DE363689459CA0C0" modified="2019-11-13" version="1">MRPIKLLFLSVLLTGFSHAQVGIGTEEPDASALLELKSESQGLLAPRMTTLQREDIESPAESLLVFDTDEDTFYFYNATTTSWSALANDTSDKRSNYKLVKSAADLTVELAAGGGSSYKLDTNTFYEINGTIALSSPIDLNNAYVAGMDPNEDVLSSSGVVFKGSTGGSIRNVTLIGTKAFEIAGPGIATNSSLLIQNTIIDGMNSVGSISGFGLYFGNIVQFLNNTNGITYSNIGNLLLNNQAWPNSNNGTFETFSDNFGLIEKVSGFSSVNGSDVALDVSSNPNVATGVLQGTVFTGTTSASSGYVKAYTSGSYTGYNFSNAWTVSAPGIPRESDDVATGDINFSANVGNGELTTFSGTGSGFRKKVTGTTASGELFRFEKSGNNRIIYKGNKTRFFGANASISFQARDLTSNTDGTIPTIYILYIAKGKGTGSASVITQTKVYGRASDESDIIALPIIGTIELDTDDYIEVWAERFTGGGDMLTVSLNVTLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKP6</accession>
    <name>A0A5C6ZKP6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF922 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_04200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010321">
        <property type="entry name" value="DUF922"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06037">
        <property type="entry name" value="DUF922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022807065" evidence="2">
        <location>
            <begin position="26"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="129"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="183" mass="21328" checksum="E9C48C109C84DD18" modified="2019-11-13" version="1">MEMMASKYALLFAFMLFFGVQQETAFTWQPDRNLTWADYQAVVDPNSDAVALTAAGITFSYSLKEADRRFVSFVATAEANFYPESSWYKKDKCNETVLAHEQLHFDIAELHVRMLRAALNDLETTQAIKSDLRRVHRNANRDMAKMQNTYDLETNNSRDVEQQEQWASLVKNELEKYQQFESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKY5</accession>
    <name>A0A5C6ZKY5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ATP synthase subunit alpha</fullName>
            <ecNumber evidence="9">7.1.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ATP synthase F1 sector subunit alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">F-ATPase subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">atpA</name>
        <name evidence="13" type="ORF">ESY86_07745</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:57720"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.2" evidence="9"/>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18113">
        <property type="entry name" value="ATP-synt_F1_alpha_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01132">
        <property type="entry name" value="F1_ATPase_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.150.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01346">
        <property type="entry name" value="ATP_synth_alpha_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000793">
        <property type="entry name" value="ATP_synth_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038376">
        <property type="entry name" value="ATP_synth_asu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033732">
        <property type="entry name" value="ATP_synth_F1_a"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005294">
        <property type="entry name" value="ATP_synth_F1_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00306">
        <property type="entry name" value="ATP-synt_ab_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039088">
        <property type="entry name" value="F_ATPase_subunit_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="SSF50615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00962">
        <property type="entry name" value="atpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="4 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0139">CF(1)</keyword>
    <keyword evidence="9" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="5 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATP-synt_ab_N" evidence="12">
        <location>
            <begin position="28"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_ab" evidence="10">
        <location>
            <begin position="151"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_ab_C" evidence="11">
        <location>
            <begin position="396"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="171"/>
            <end position="178"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Required for activity" evidence="9">
        <location>
            <position position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TXD89667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="528" mass="56747" checksum="EF7EA4C0D9A18A70" modified="2019-11-13" version="1">MAEVNPAEISAILKQQLSGFEAGASLDEVGTVLTVGDGIVRAYGLSNVQYGELVEFDGGLEGIVLNLEEDNVGIVLLGTSVGVQEGSTVKRTGRIASVNVGEGIVGRVVDTLGNPIDGKGAIAGETYRMPLERKAPGVIYREPVTEPLQTGIKAIDAMIPVGRGQRELVIGDRQTGKTTVCIDAILNQKEFYDAGNPVYCIYVAIGQKASTVANIAKTLEEKGALAYTVIVAANASDPAAMQVYAPFTGASIGEYFRDTGRPALIVFDDLSKQAVAYREVSLLLRRPPGREAYPGDVFYLHSRLLERSAKIINNDAIAREMNDLPDILKPMVKGGGSLTALPIIETQAGDVSAYIPTNVISITDGQIFLDGDLFNSGVRPAINVGISVSRVGGNAQIKSMKKVAGTLKLDQAQFRELEAFAKFGSDLDAVTLNVIEKGRRNVEILKQAQNDPYPVEDQVAIIYAGSKNLLRDVPVNKVKEFEQEYLEFLRTKHGDVLSTLKAGKLTDEVTDTLTDVAKDLSAKYRNKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL04</accession>
    <name>A0A5C6ZL04_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ribosomal protein S12 methylthiotransferase RimO</fullName>
            <shortName evidence="7">S12 MTTase</shortName>
            <shortName evidence="7">S12 methylthiotransferase</shortName>
            <ecNumber evidence="7">2.8.4.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Ribosome maturation factor RimO</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 11" type="primary">rimO</name>
        <name evidence="11" type="ORF">ESY86_03915</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>[sulfur carrier]-SH + AH2 + L-aspartate(89)-[ribosomal protein uS12]-hydrogen + 2 S-adenosyl-L-methionine = 3-methylsulfanyl-L-aspartate(89)-[ribosomal protein uS12]-hydrogen + 5'-deoxyadenosine + [sulfur carrier]-H + A + 2 H(+) + L-methionine + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:37087"/>
            <dbReference type="Rhea" id="RHEA-COMP:10460"/>
            <dbReference type="Rhea" id="RHEA-COMP:10461"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:29961"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="ChEBI" id="CHEBI:73599"/>
            <dbReference type="EC" id="2.8.4.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="7">Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the methylthiotransferase family. RimO subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.4.4" evidence="7"/>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103039">
        <property type="term" value="F:protein methylthiotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018339">
        <property type="term" value="P:peptidyl-L-beta-methylthioaspartic acid biosynthetic process from peptidyl-aspartic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01865">
        <property type="entry name" value="MTTase_RimO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005839">
        <property type="entry name" value="Methylthiotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020612">
        <property type="entry name" value="Methylthiotransferase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013848">
        <property type="entry name" value="Methylthiotransferase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038135">
        <property type="entry name" value="Methylthiotransferase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005840">
        <property type="entry name" value="Ribosomal_S12_MeSTrfase_RimO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041582">
        <property type="entry name" value="RimO_TRAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43837">
        <property type="entry name" value="PTHR43837"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18693">
        <property type="entry name" value="TRAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00919">
        <property type="entry name" value="UPF0004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00274">
        <property type="entry name" value="ribosomal_protein_S12_methylth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00089">
        <property type="entry name" value="TIGR00089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01125">
        <property type="entry name" value="TIGR01125"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51449">
        <property type="entry name" value="MTTASE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01278">
        <property type="entry name" value="MTTASE_RADICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 7" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0408">Iron</keyword>
    <keyword evidence="6 7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="11" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 7 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MTTase N-terminal" evidence="9">
        <location>
            <begin position="9"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="10">
        <location>
            <begin position="134"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="domain" description="TRAM" evidence="8">
        <location>
            <begin position="367"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD90522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="435" mass="49787" checksum="94C979C94A5198E2" modified="2019-11-13" version="1">MRTKSLKKNRINVITLGCSKNVYDSEVLMGQLKASGKDVVHEQDGNVVVINTCGFINNAKEESVNTILEYMQKKEAGEVDKVFVTGCLSERYKPDLQKEIPNVDQYFGTTELPQLLKALGADYKHELIGERLTTTPKNYAYMKIAEGCDRPCSFCAIPLMRGKHRSTPIENLVIEAEKLAANGVKELILIAQDLTYYGLDLYKKRNLAELLEHLVKVEGIEWIRLHYAFPTGFPMDVLDVMKREPKVCNYLDIPLQHISDAILKSMRRGTTHEKTTKLLKDFRAKVPEMTIRTTLIVGYPGETEADFQTLKQWVKDMRFERLGCFTYSHEENTHAYNLEDDVPENVKIDRANQIMEIQSQISWELNQQKIGQEFKVVIDRKEGNYFVGRTEFDSPDVDNEVLIDASKNYLKTGEFARIKVTEAEDFDLYGEVVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL08</accession>
    <name>A0A5C6ZL08_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_04860</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="105" mass="11759" checksum="C6518BE31AA10735" modified="2019-11-13" version="1">MAKFIAIDANGLNALFSGSDITFVNPHCKKEKLANLSEKTANLSQTDQLDSRVINLDGFCSAQFQFELFTWETDCPKPKAVFNEHFSSRLSFLYLENASPPPRLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL20</accession>
    <name>A0A5C6ZL20_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SulP family inorganic anion transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_01840</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015116">
        <property type="term" value="F:sulfate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="206"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="266"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="310"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="342"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="365"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="397"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfate_transp" evidence="2">
        <location>
            <begin position="17"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="558" mass="59649" checksum="A8F9BC29506F1D76" modified="2019-11-13" version="1">MILGQKTRKNFTQNPKNDILSGLTVALALVPEAVAFSFVAGIDPLVGLYGAFMVGIVTALFGGRPGMISGATGAMAVVMVHLIQKGNDVGVALDTPIENLGLQWLFITLLFVGAIQIMAGVFKLGKFVRLIPHPVMMGFVNGLAIVIFLSQLGLFPNAVPKDISFLNETSAWFSALFSNAGFWKMMGFIGLTMAIMYGLPKLTKKIPAALIAIVVVAGITILGGIEISTVGSFIKEGGGTGLQGGLPSFQDQIFGLFGTLAGHWDLIISTAFILAAVGLIESLMTLNLIDEMTETRGNGNRECVAQGGANMLNGLFGGMGGCAMIGQSIINVDSGGRGRLSGAVAAVALLCFILFGAPLIEQIPIAALVGVMFMVVIGTFAWSSFRIIKKIPISDAIVLVAVSAITVWQDLAIAVIAGVIISALVFAWKNATMIRARKRIQPDGTKTYEIWGPLFFGSIQNFNSKFDIKNDPQNVEIDFVESRVSDHSALEAIFNLVKKYEAEGKTIKLKHLSEDCKLLMAKASPKFKEVIVEAIDDPRYHLAADPEKFTKPLSEYPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL39</accession>
    <name>A0A5C6ZL39_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_04995</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="7"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="39"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="242" mass="26875" checksum="29B112A53E58722D" modified="2019-11-13" version="1">MINNNVIHVEGLTKMFGDFTAVDAITFDVKKGEIFGFLGANGAGKTTAMKMLIGISKPTSGKANVAGFDVFTHAEDIKKNIGYMSQKFALYDDLTVKENITFFGGIYGLTRTRIKEKSEALIEELGLENVATKLVGSLPLGWKQKLSFSVALLHDPKIVFLDEPTGGVDPITRRQFWEMIYKASHQGTTVFVTTHYMDEAEYCDRVSIMVNGKIEALDTPKKLKEQFKATNMNDVFLKLARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL44</accession>
    <name>A0A5C6ZL44_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glutamate dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_04120</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3 7">Belongs to the Glu/Leu/Phe/Val dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004353">
        <property type="term" value="F:glutamate dehydrogenase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01076">
        <property type="entry name" value="NAD_bind_1_Glu_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006095">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033524">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006096">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006097">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014362">
        <property type="entry name" value="Glu_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033922">
        <property type="entry name" value="NAD_bind_Glu_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00208">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02812">
        <property type="entry name" value="ELFV_dehydrog_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000185">
        <property type="entry name" value="Glu_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00082">
        <property type="entry name" value="GLFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00839">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00074">
        <property type="entry name" value="GLFV_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 3 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ELFV_dehydrog" evidence="8">
        <location>
            <begin position="198"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="117"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="365"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="6">
        <location>
            <position position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000185-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD90562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="432" mass="48160" checksum="2198B796FB26E362" modified="2019-11-13" version="1">MTLVADQKKQKKPAVRGMMENVMEQFNSAADQINLHPNIRKILSITNNEIVVNFPVKMDNGEVEIFRGYRVQHNNALGPYKGGLRYHPTVDIDAARALAMWMTWKTSLAGLPYGGGKGGIQLDPSKYSKDELERITRRFTFALADNIGPEHDIPAPDINTNSQTMAWMADTYMSTRPPAERTANQHVVTGKPEGSGGLEGRDRATGYGVYLTIKFWAEKNEMTLKNKRFIVQGFGNVGYWAAHFLENEGAKLVAVQDAYGSIENQDGINVASLFNYVQAHKGSFVDFPDADPIDKDSFFGTDCDICIPAALGNQITKENASQLKATLIAEGANGPINVEGEKALLKLGKTIIPDILCNSGGVIGSYFEWLQNRNGELWQLDEVMVKLDKKLNESFNKVWEYSQRRSMDMRTAAYCIAIERIEKAYVQRGIFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLA9</accession>
    <name>A0A5C6ZLA9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08570</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="116" mass="13247" checksum="F479B6D7F016DD9E" modified="2019-11-13" version="1">MKTQFLTLKEVKLHNNCPECFSNEGLHLRFKQKFVQNALYKSVTSDIQNEMQCHTCNSGISPGSWTREIDQVVAYQERAIKPKPKSIKLTKLAWIIVILEAVLIFGVLLFAFGVFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLE4</accession>
    <name>A0A5C6ZLE4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Class I SAM-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041497">
        <property type="entry name" value="Thump-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18096">
        <property type="entry name" value="Thump_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thump_like" evidence="1">
        <location>
            <begin position="322"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="394" mass="45079" checksum="92A5E1774C3C74C8" modified="2019-11-13" version="1">MNLHLLNSDIQKFIDDHLDTDVSTLLFKGSDFETVTTLEIVAQIESKLKCKNKLPTWFATEGIYYPNKLNIEQTSSETAAAYKASVLSGNRIIDLTGGFGVDSFYFSKHFNEVVHCEMDAELSKIASHNFTQLKTRNIETQVGDAMALLKTRDQKWDWIYVDPSRRHDSKGKVFFLSDCLPNVPEHLEVLFRFSNHIAIKTSPLLDLKAGINALNHVKTIHIVAINNEVKELLWLLEKGHQDRIAIHSINIGKNGTETFEFYLEDEGENESTFSQPLAYLYEPNAALLKSGAYKTLSKKLEIHKLHQHSHLYTSDQILNFPGRRFKIEKLLDFNKKALKKEAFQKANISTRNFPESVEQLRKKFKISDGGEQYLFFTTTMEDQKIVVVCSKIDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLJ8</accession>
    <name>A0A5C6ZLJ8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phenylacetate-CoA oxygenase subunit PaaC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">paaC</name>
        <name evidence="1" type="ORF">ESY86_01935</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010124">
        <property type="term" value="P:phenylacetate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007814">
        <property type="entry name" value="PaaA_PaaC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011882">
        <property type="entry name" value="PaaC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05138">
        <property type="entry name" value="PaaA_PaaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037834">
        <property type="entry name" value="PA_CoA_Oase3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02158">
        <property type="entry name" value="PA_CoA_Oxy3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="250" mass="28821" checksum="84EA2C9E3E6BA272" modified="2019-11-13" version="1">MNTNLYNYILGIADNSLILGQRMGELCGHGPNLETDIACTNISLDLFGQVRGYFQYAAKIANDGRTEDDIAMLRKERDYLNVLLAEQPNTDFAYTIGRQFLFDVYHLLFLTELEKSKDLTLSAIAKKSIKEVRYHQRFSSDWVKRLGDGTEESHSKMQQAINDLWTYTDELFHQTEADKAMVEEGIGVDVTKLKKDYYEKVSTILEQATLEIPESKYFQKGGKEGIHTEHLGFLLSELQYMQRAYPNMDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLQ5</accession>
    <name>A0A5C6ZLQ5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_01805</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022847835" evidence="2">
        <location>
            <begin position="24"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="65"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="109" mass="12974" checksum="6ADC2CAD0F67AA9E" modified="2019-11-13" version="1">MKKYLSLCLIAFALCISTQDMMAQNRIEIDRAANQKTKTLRKTLKFDSTKMEDVYEAYKAYELIYQNIDNNLEKNTERLKEINNRLDEKLKGILTEEQFELYLNTYRSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLS3</accession>
    <name>A0A5C6ZLS3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_05525</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="132" mass="15536" checksum="D82ED5E843DFDCB8" modified="2019-11-13" version="1">MDSFIGIRFKKETAKRFQTFSRTYFKSHTEAMVTMLDFFFYNEISPKEKLGPTGRTIEAKLLKRINAVIAIMRDVEKTQTKPTVAMIQSLFETEEPTKKPLIVEKKYAEEKKEVRFREIESARFTTKGRAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLT9</accession>
    <name>A0A5C6ZLT9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_01365</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022916626" evidence="1">
        <location>
            <begin position="26"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="474" mass="50705" checksum="741BFD1C34B7E049" modified="2019-11-13" version="1">MTHNYFKTTGIFLLMCLLTSSIAISQVGIGTETPDDSSILDMQSTSAGLLIPRMTDTERDGILEPAEGLQVYNTTNKTLDIYIDGVWNSFLSQKSANANRSNLVTVYSVDDLPTPAAGAITLDATKMYVFSGMVDIGSNHIIMNGAGLRGTDPQKDGVMSSASGGVLRSTATNIFMQNFTVIPTAGSAYDFSGTAANFCNIFSGCSVIGGSVGQISGFNAITIIQNYWNVTDGVKVTGNVGKFTSSYNFIVGISSGAGVEFLAGLTANDIDMANNYFIYAGQTGIKVNAGAAVDRGRMTTNMFRDVTTPLSGIDSYSPGWSMKQNTNIPDSRAYSFIYFNGNTAPTLLPTQNFFTKIEGATEVVSQKRFTGNNTGKITYTDKEPITAKISVVISAKANENNSQYSIGIRKNNEMTLTGPVASMASTANNQSFQIILNTEVDLETDDAIEVYIARSNGSTDNEITVSELQFRVTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLZ7</accession>
    <name>A0A5C6ZLZ7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Two-component sensor histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_02355</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="259"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="300"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD90822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="513" mass="57413" checksum="13A08AA3538678D7" modified="2019-11-13" version="1">MNDSKYRYILYLIVLVIIATIGIQAYWNYKNYLANKQQLINDVQVSLDGAIDDYYANLAERSTIGFGIEDMTQKEFLSNGKFDSILDGIEMSETDGFSGLESIDPKLIEGIAIVKGINADSILSRLQIKGSVLNNKKFSPASQLAENAQKDLLTSKNVRLLTSKVIISMTTDSLSLVGIDTLLQAELLRKDIVINYLIAYKDPSADMDYYDAIDKNLETIDSLKYSSYLQTSSKSTFLPKQSELSILFSNITETIFKRIAIGLIISTVLVLTVISCLFYLLHIINQQKQLAEVKNDLINNITHEFKTPISTIGVALESLGHFDGLSDKDRTQRYLQLSKAQLSKLNVMVEKLLETATLDSEAIELQLESVNLNALLKQLVEKHGFQHKDKSIVLKPSEVEITIHVDAFHFENAINNILDNALKYGGSEIDISSEVLRDSVEILISDSGSSLTKGQKEQVFDKFYRVPKGNQHDVKGFGIGLYYSKKIIEKHQGRIVLELKSNLTTFKISLPNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM39</accession>
    <name>A0A5C6ZM39_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Acetyltransferase</fullName>
            <ecNumber evidence="2">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_02570</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016407">
        <property type="term" value="F:acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039369">
        <property type="entry name" value="LacA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024688">
        <property type="entry name" value="Mac_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43017">
        <property type="entry name" value="PTHR43017"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14602">
        <property type="entry name" value="Hexapep_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12464">
        <property type="entry name" value="Mac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01266">
        <property type="entry name" value="Mac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Mac" evidence="3">
        <location>
            <begin position="4"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU367021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD90862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="185" mass="20632" checksum="8753DD4F913F0065" modified="2019-11-13" version="1">MTEKEKMIAGELYRPKDAQLVDERQEAKLLFQQFNAMDESQKEVRNQLLYDLFGKAEEHLWIEPPFYCDYGYNIKIGKHVFINYNCCILDGTLVKIGDNCMFGPNVQIYTATHPLEYEARNSGQEFAKPISIGNNVWIGGNATICPGVTLGDNVVVGAGAVVTKDFPENVVIAGNPAKVINRIAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM66</accession>
    <name>A0A5C6ZM66_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">M20/M25/M40 family metallo-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_02225</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00758">
        <property type="entry name" value="ARGE_DAPE_CPG2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="2">
        <location>
            <begin position="167"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="353" mass="38897" checksum="7C25C108296221DB" modified="2019-11-13" version="1">MIATLTQEAIALLKNLIETQSFSSEEDKTAELIEQWFKTHNIDATRTKNNVWAVNKNFEEAKPTLLLNSHHDTVKPNSAYTKDPFKAIVADGKLFGLGSNDAGGCLVSLLATFTYFYEHEDLNYNLVMVASAEEENSGSNGLNSMLQIMPKVDVAIVGEPTLMQLAIAEKGLVVFDAKVKGRPSHAAHPNPDNAIYNCIEVLQWFKDYSFKKTSETLGEVKMTVSQIKAGEQHNAIPAEVDLVIDVRVNDCYSNAEIAEMLQNESPCDSIIPRSLRLNSSSIPKEHPLVQSGLAMGRETYGSPTLSDQAVLACPSLKLGPGDSTRSHSADEFIYLKEIEEGIGLYVELLERIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM84</accession>
    <name>A0A5C6ZM84_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SsrA-binding protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Small protein B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 4" type="primary">smpB</name>
        <name evidence="4" type="ORF">ESY86_00895</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="3">The tmRNA-SmpB complex associates with stalled 70S ribosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SmpB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070929">
        <property type="term" value="P:trans-translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09294">
        <property type="entry name" value="SmpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00023">
        <property type="entry name" value="SmpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023620">
        <property type="entry name" value="SmpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000037">
        <property type="entry name" value="SsrA-bd_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020081">
        <property type="entry name" value="SsrA-bd_prot_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30308">
        <property type="entry name" value="PTHR30308"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01668">
        <property type="entry name" value="SmpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74982">
        <property type="entry name" value="SSF74982"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00086">
        <property type="entry name" value="smpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01317">
        <property type="entry name" value="SSRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD91176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="152" mass="17742" checksum="B6A3D0BEF7C834F4" modified="2019-11-13" version="1">MQNQINIKNKKAKFEYELLDKYTAGIVLTGTEIKSIRDGKASIAEGFCEFNARGELFIINMTIQEYVYGNYYNHAPKAERKLLLNRKELKKLEKEISTKGLTIVPLRLFLNDRGLAKLIISLAKGKKLYDKRNTIKDRENKRNLDRIQKIYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM90</accession>
    <name>A0A5C6ZM90_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Exonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00945</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006054">
        <property type="entry name" value="DnaQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Exonuclease_RNaseT/DNA_pol3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035901">
        <property type="entry name" value="GIY-YIG_endonuc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01541">
        <property type="entry name" value="GIY-YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00465">
        <property type="entry name" value="GIYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82771">
        <property type="entry name" value="SSF82771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00573">
        <property type="entry name" value="dnaq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GIY-YIG" evidence="1">
        <location>
            <begin position="195"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="457" mass="52557" checksum="F28923AD8124C9CA" modified="2019-11-13" version="1">MYAILDIETTGGKYNEEGITEIAIHKFDGHNTIDQFISLVNPERDIQPFVVKLTGINSNMLKNAPKFYEVAKRIVEITEDCIIVAHNAEFDYRILRTEFKRLGFPYKRKTLCTVELSQQLMPEQESYSLGKLTRALGIPVSDRHRANGDAMATVKLFKLLLNKDSDKHIITDSVKVHVATKMNDNHIQIIEDLPAITGVYYLHDEEAQIIYIGKSKNIKHRVNQHLTNTSSKSKKLQLLVKSVSYEATGSELVALLKESEEIKRIKPKFNRALKRKRFTHGLYSFTDEDGYLNLRYEKILPQKTYITTFANWQSAKSFMDKMLEKYTLCQKLTGLSSTKSNCFNYTIKNCNGACLQEESAIDYNKRVQEFIDHNSYSDRNMAIVDQGRAIDERSVIYIKDGVFKGLGFTELNYQINNSSVLENIISPMENNRDTQHIIQSYLRKHSRVKIISIPTLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMH1</accession>
    <name>A0A5C6ZMH1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_06500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="151" mass="17666" checksum="500ED25733335C59" modified="2019-11-13" version="1">MPRNTRDIFQFIPCGLAPMLLIYDIKNRPWLYEPVPSGNSDFNKIGALIASLFKRKQYSSEIIYVKPEDLQSLFASNSFFTKKMISKELNIIEDYQFLFFEFCSAQQIDMQLISEKKSLELLELLMAYSRDFKSFLLENPKDGVVIFNGQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNL7</accession>
    <name>A0A5C6ZNL7_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Triosephosphate isomerase</fullName>
            <shortName evidence="3">TIM</shortName>
            <shortName evidence="3">TPI</shortName>
            <ecNumber evidence="3 4">5.3.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Triose-phosphate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">tpiA</name>
        <name evidence="5" type="ORF">ESY86_04285</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:18585"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="5.3.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the triosephosphate isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.1" evidence="3 4"/>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00189"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004807">
        <property type="term" value="F:triose-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00311">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00147_B">
        <property type="entry name" value="TIM_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035990">
        <property type="entry name" value="TIM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022896">
        <property type="entry name" value="TrioseP_Isoase_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000652">
        <property type="entry name" value="Triosephosphate_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020861">
        <property type="entry name" value="Triosephosphate_isomerase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21139">
        <property type="entry name" value="PTHR21139"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00121">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51351">
        <property type="entry name" value="SSF51351"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00419">
        <property type="entry name" value="tim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00171">
        <property type="entry name" value="TIM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51440">
        <property type="entry name" value="TIM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 3 4" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="3 4" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="2 3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="9"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="233"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="active site" description="Electrophile" evidence="3">
        <location>
            <position position="94"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="166"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="249" mass="27252" checksum="9B68576B5D588865" modified="2019-11-13" version="1">MRKHIVAGNWKMNNDLAETETLLSDLKKQSKTSNAEVMISPAFTNLWHAFQSTREDDIEVIAQNMHFAENGAYTGEVSASMLKSIGVKTVILGHSERRAYYNETDASLAKKVDAALANELRVIFCFGEELKDRKAGDQEKIVASQIKNALFHLDAAAFKNIVLAYEPVWAIGTGETASPEQAQDMHAFIRKTLDGKYGVNVANTMSILYGGSVKPANAREIFSKPDVDGGLIGGASLKAEDFYAIVNAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZP04</accession>
    <name>A0A5C6ZP04_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">HAD-IIIA family hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_03480</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the KdsC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010023">
        <property type="entry name" value="KdsC_fam"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006118">
        <property type="entry name" value="KDO8-P_Ptase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01138">
        <property type="entry name" value="C1.6.2:_Deoxy-d-mannose-octulo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01670">
        <property type="entry name" value="KdsC-phosphatas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="4">
        <location>
            <position position="19"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="21"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR006118-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="176" mass="19599" checksum="98E56BFF1BFDDBD4" modified="2019-11-13" version="1">MEDKSYKEYLEHISTFILDVDGVLTDGTVTIMTNGDMLRRMNIKDGYALKIAKDAGYNICIISGGNNLGVQKRLEGLGITDIYLGAHHKIDQFEIYLNEKSIKPENVLYMGDDIPDIPVMKLVGLPTCPQDAAIEVKGISKYVSHKLGGKGAVRDVIEQVMKVQDKWNGNFDAKYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZP18</accession>
    <name>A0A5C6ZP18_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">Elongation factor Ts</fullName>
            <shortName evidence="5">EF-Ts</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">tsf</name>
        <name evidence="7" type="ORF">ESY86_02040</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the EF-Ts family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.20">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00050">
        <property type="entry name" value="EF_Ts"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036402">
        <property type="entry name" value="EF-Ts_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001816">
        <property type="entry name" value="Transl_elong_EFTs/EF1B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014039">
        <property type="entry name" value="Transl_elong_EFTs/EF1B_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018101">
        <property type="entry name" value="Transl_elong_Ts_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11741">
        <property type="entry name" value="PTHR11741"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00889">
        <property type="entry name" value="EF_TS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="SSF46934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54713">
        <property type="entry name" value="SSF54713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00116">
        <property type="entry name" value="tsf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01126">
        <property type="entry name" value="EF_TS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 7" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="4 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF_TS" evidence="6">
        <location>
            <begin position="74"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="region of interest" description="Involved in Mg(2+) ion dislocation from EF-Tu" evidence="5">
        <location>
            <begin position="82"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD90766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="321" mass="34853" checksum="D7FA396A23D65A45" modified="2019-11-13" version="1">MVKVTAAEVNKLRQATGAGMMDCKKALVEAEGNFDKAIEVLRKKGQKVAEKRADRDSSEGAAVSKINADETAGVAIVLGCETDFVGKNENFVALAEQLGDIALNCKTKEELLDADFEGMTVSDKLTEQTGVIGEKLDITAFERLEAPFVGTYVHINKIAALVALSAKVDKAETLVKDVAMQVASMGATTLSFKDFDPGFIASETEARIAVIEKDNIELGRLGKTLKNVPSYISMAQLTPEVVAEAEAAAKAELKHEGKPEQIWDRILPGKMDRFISDNTTLDQEKALLDQKFIKDDKMTVAKYIETYGNVEVVGFRRVSVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZP51</accession>
    <name>A0A5C6ZP51_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">N-formylglutamate amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_01655</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007709">
        <property type="entry name" value="N-FG_amidohydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05013">
        <property type="entry name" value="FGase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="232" mass="26741" checksum="E1A218325ED0509B" modified="2019-11-13" version="1">MKLALTCEHGGNQVPKQHEYLFNANPEVLNTHRAYDLGALDLFKRLKPLAHFSKSSQTSRLMIELNRSLLHPQLFSEFSKNLSVSEKLQLVEDIYRPYRNSVEKWIGVQIEAGEDVVHISIHSFTPKLNHEERSCDIGWLYDPKRTAEKTLCVQLKALLLEADPQLNVRFNYPYLGTADGFTTYLRKTFPKHYIGIELEVNQKFFIKNVMDAKIKAALFSAISKISRIPIHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZP89</accession>
    <name>A0A5C6ZP89_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4870 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_01220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019109">
        <property type="entry name" value="DUF4870"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09685">
        <property type="entry name" value="DUF4870"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="148" mass="16918" checksum="08B7838E73BB8B9C" modified="2019-11-13" version="1">MLENNHKNIATFIHLSTFSRFVFPLGNFIAPILLWALNKGKSEFVDAHGKQAINFQISILLYTVIIGMLTIPFFIFKFMSGIDYIDFNGFENFHFNIHEPSPLLYFTGGLGILAVFGFLLELVFIVIASLKARDGELYRYPLTITFLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPW9</accession>
    <name>A0A5C6ZPW9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00025</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="121" mass="14087" checksum="5E561CB5A136A870" modified="2019-11-13" version="1">MMAKLPLKILHGYVLLSLLLFFTVQSLKFYAVVSPIWMLHHLNDFLVIPMVATLCLHGVWLIKKDTTIRLNLFTILSLVALFSLVFEYYLPQQSYRYTGDLWDVISYVLGGFMFYVFQKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZQ44</accession>
    <name>A0A5C6ZQ44_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">4Fe-4S dicluster domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_00130</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12838">
        <property type="entry name" value="Fer4_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="63"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD91043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="117" mass="12967" checksum="59A153BF92AE0C25" modified="2019-11-13" version="1">MAIIITDECINCGACEPECPNTAIYEGADDWRYKDGTSLEGKVVLPNGNNVDADEAQEPVSDEIYYIVPDKCTECKGFHDEPQCAAVCPVDCCVPDDEHVETEEELLGKQRFMHPPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZQ53</accession>
    <name>A0A5C6ZQ53_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Argininosuccinate synthase</fullName>
            <ecNumber evidence="2">6.3.4.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Citrulline--aspartate ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_02255</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.5" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00113"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004055">
        <property type="term" value="F:argininosuccinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001518">
        <property type="entry name" value="Arginosuc_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018223">
        <property type="entry name" value="Arginosuc_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024074">
        <property type="entry name" value="AS_cat/multimer_dom_body"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11587">
        <property type="entry name" value="PTHR11587"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00764">
        <property type="entry name" value="Arginosuc_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69864">
        <property type="entry name" value="SSF69864"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00564">
        <property type="entry name" value="ARGININOSUCCIN_SYN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD90803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="411" mass="45577" checksum="45B030660969995B" modified="2019-11-13" version="1">MKEATNSSSEAQSQSKKSGKLVLAYSGGLDTSYCAVSLSKAGYEVHSVSVNTGGFSSEEIEHIESNAYKMGVSTYKNIDAVASYYEKVIKYLIFGNVLKNNTYPLSVSAERIIQAIEIVEYAKSIDAQFIAHGSTGAGNDQVRFDMIFQTLAPHIEIITPIRDQKLTRQEEIDYLKQHGVDSSWEKSKYSINKGLWGTSVGGEETLTSEKPLPDSAYPSQLKHSDPEKVLLRFLEGELVAVNGVENSPEINIEVLNDMASAYAIGRDIHVGDTIVGIKGRVGFEAPAALVIIKAHHLLEKHTLTKWQLQHKDYLSSFYGMHLHEGQYLDPVMRNMEAFLESSQAQVSGEVIVTLKPYHFSLDGIRSEHDLMNAKFGAYGEVNSGWTAEEAKGFIKIFANQNKIYHQVNQTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZQV6</accession>
    <name>A0A5C6ZQV6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HDIG domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_01425</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006675">
        <property type="entry name" value="HDIG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011624">
        <property type="entry name" value="Metal-dep_PHydrolase_7TM_extra"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011621">
        <property type="entry name" value="Metal-dep_PHydrolase_7TM_intra"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07698">
        <property type="entry name" value="7TM-7TMR_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07697">
        <property type="entry name" value="7TMR-HDED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00277">
        <property type="entry name" value="HDIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="265"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="297"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="323"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="344"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="366"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="390"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="423"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="domain" description="HD" evidence="2">
        <location>
            <begin position="477"/>
            <end position="619"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD91273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="681" mass="77577" checksum="AAB24E729998149B" modified="2019-11-13" version="1">MKDLVNKWYKNHAFLYKILLFISTTILIVYLFPKSGKFKYDFDKGKPWQSENLYAPFDFAIKKSAEELEKEQLEVSENSPVYFEIDLAVKPQVYKAYDDKFKTAFTDSVLKANPELKNVGIAALDKIYAVGLLDENYDYVAYKEVIILEDQTQKTRTEFSKLTAFDGFKKFIGTELRSKNDLRFKTAFVSMFFDIVKPNLAINKSLTQSSIKEKLDAISLVRGSVEKGTLLISKGEIVEGNKYDVLKSLEAEYESQVWSASDYNLVIFAYALLVALVLLMLLLFLRKYRIEVFMDNTKVTFIFFNILLMILLTTLIVNYNAQYVYVIPLCILPLVLKAFFDARLGLFAHVLTILLLGFIVPKSNEYIFLQIIAGIVTILTVSELYKRANLFISVGQITLIYIISYFAFYVIHEGSLDNIDFTTFGLFVICGLATLFVQPLIYIYEKLFGLVSDVSLLELSDTNTKLLKELSNKAPGTFHHSLNVANLAEASANEIGANAMLIRVGALYHDIGKMKNPTFFTENQATGLNPHDELAPRESAKIIIDHVINGIETAKKNNLPDRVIDFIRTHHGTSLVYYFYMKEKGMDEDTTEDDFRYPGPQPFSKETAILMMCDSVEAASKSLKDPTSSKIDKFVETIIAKQMEDGQFLNANITFKEIQIIKKVLKSKLANIFHLRIEYPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZA97</accession>
    <name>A0A5C6ZA97_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_20060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000056">
        <property type="protein sequence ID" value="TXD86495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="78" mass="9219" checksum="F7DE91EC10C82045" modified="2019-11-13" version="1">MEIHFENIKEIIIQNLKHAKFNVFASVAWVGENFIIRELTNCLKRGIQVEIIVNDDDRFLNYKSKFTEFLELGGKLYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAB5</accession>
    <name>A0A5C6ZAB5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_19985</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000053">
        <property type="protein sequence ID" value="TXD86532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022723615" evidence="2">
        <location>
            <begin position="26"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="559" mass="61809" checksum="DB9A92226F34A85F" modified="2019-11-13" version="1">MKHKRIKTYLKFGILLFGISAIAIACQKDDNVSTEQNSELKIPQIETISYDDDNTTFNNLKSQYNLDRYRATKFTGNIQAKSTTDTLGLVIETDIIKQATLGDYTSYTIKIVHQNDSTVFYNLTIEYKNGESDLFITKYTPTEYWINNKDKPFQGKVQSKRATLTQYTDPEEAFEEGYTGNPELGSGPGGGGGAQYGSDYPVGCLGTVVVTTELVAYKCGCGDWPWDDCEGCSTSPQWPGYDQVTLYACEENWDIEDPYDPGDTGNPGGGSLPDPTDDDPSITVTIRPEECTEQITGDLDGDCALSPYEFCMLGDNSQEICDCVADDNTLAECIEEDELISDCNLLENLSLSADFATKMQELINNTTGNTEIAYFGSTDDNDDTTFPDRVESQPDQRGVNVSISSNVPVDVFIHNHFNNGLGSLSVFSGSDLYTLYQLYTNGNISDVDEYVMVVATPGSNASSTDDDTVYAITINDLNSFAEFGSKFLIDDFLIDALYQNIGNKIDTNISINLNEERFAKLLKDFSSGLTLHRGDRNDLTSWTKLKVKNDNTIKESNCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-02-10" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAF1</accession>
    <name>A0A5C6ZAF1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GNAT family N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000034">
        <property type="protein sequence ID" value="TXD86916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039533">
        <property type="entry name" value="Satl1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10545:SF60">
        <property type="entry name" value="PTHR10545:SF60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="159" mass="18117" checksum="B2B39D1DEE31AD43" modified="2019-11-13" version="1">MDISIRRATKEDMARVLELIYELALHENKPNAVELHVEDLEKAGFGDEKEFICFVAEVDGKIEGSALIYNRFSTWKGSVLHLEDLVVSKRMRGSGLGTTLLNEVVRFGQEIGVKRISWEVSEGNENAMKFYQNKGADIKRDWNVVHLDEEGIKTYLSQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAJ3</accession>
    <name>A0A5C6ZAJ3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">LacI family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_20595</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000091">
        <property type="protein sequence ID" value="TXD86113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001761">
        <property type="entry name" value="Peripla_BP/Lac1_sug-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00532">
        <property type="entry name" value="Peripla_BP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="5">
        <location>
            <begin position="3"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="4"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD86113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="345" mass="38789" checksum="8962C3287F36C103" modified="2019-11-13" version="1">MSKVTLKDISKILGISTSTVSKALKNYSDINVETKLKVQELAKKLNFTPNAFAQSLRSRETKIIGILVPELVHHFFSNVIDGAIHEAEKHGYLVIVLQTHECYEDEIKQLKLLVDKNIDGILLSLSDKTVKYDHIKNIIDEGMPVVLFDKITHLIDCPKVIINDRKAAFSATEHLIKTGCKKIAHITGPLKPKTTIDRFMGYKIALETYNMPFDKSLIYTSENLFFEDGYRLAGQMMAEHPDIDGVFAFIDLVAIGVLKGLREQKIKVPKQVAVIGFSNWLMSKTTTPSLTTIDQPGYDMGKQAFQLLLKNLNQKREGKVFTSEIVEIPTRVVVRKSTNAIIDNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAP8</accession>
    <name>A0A5C6ZAP8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_20300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000064">
        <property type="protein sequence ID" value="TXD86394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="521" mass="58032" checksum="76F0D3D0A9DD9BED" modified="2019-11-13" version="1">MRNAIATLPFLQQTLESCCDEPLDLYIKDSPDDNGTEPNTVTQNMWTSQDIWVRNSEDGGLEHQNPEYTTSDPFSSPNYIYVRVINNSCSTSSGNETLTVNWAKANTALAWPQNWNGDLTDNDDNNFDPTDGGGDPLGGVLPIVTIPLLQGGEETIVSIPWVVPNPNDYSDNDNPWHFCLIARIDSTDDPMGTYTSNPNVMVRNNNNQAWKNITVVDLVSDERSGSVLVANPSNTPRTFFLELQKETNEGGKPIFDEAEVTIKMDDVLFNAWERGGKLAEELDPTLEEKKKLVKGNNVILDNIAFEANEMGLLTLYFNFLTEELTDKTEYTYHVIQKDANTGEVIGGETYVIKKEDRSTFIADAGGDKEVDFNETIIISAEDINEPAAYNWYDNDGNLVYQGKDLTVTADVVKKYKLEVVATTDGFKDYVDVEVKFKPSLIESISPNPTSDNATINYKINDTNSAYLMVIGYYGSNTSNNYILDTNTQQTQIDTSNYSLGYYTVALVCDGEIVDAKTLIKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZB45</accession>
    <name>A0A5C6ZB45_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HNH endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20735</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000112">
        <property type="protein sequence ID" value="TXD85903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00085">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002711">
        <property type="entry name" value="HNH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01844">
        <property type="entry name" value="HNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00507">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNHc" evidence="1">
        <location>
            <begin position="9"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD85903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="239" mass="27862" checksum="8020B26EC0F9CCA8" modified="2019-11-13" version="1">MAFNKKVVEDSLISCGRHCSLCHKFCGTKIELHHIKQRKDGGEDSFDNCLPLCFDCHADVMQYNPDHPKGKKYTESELKRHRNNWYEKVKNSEGTVITNSSYLNLDKATFERLNELLDSKNLMYFIKQNGFLGGSFPDKIYEDIYKFLIECELPEFEFIDADLEGLKSELRQNMEKLDELVTKHTFGAGIGKQGIPREWEMQEPERLDKAIEDFTNLTPIVTENYESLIKLGRRKLYTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZB85</accession>
    <name>A0A5C6ZB85_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_20815</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000135">
        <property type="protein sequence ID" value="TXD85741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD85741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="91" mass="10732" checksum="D65D35619954174D" modified="2019-11-13" version="1">MIEYNTKRNQLKVKYYVGINKTAEKIIQVDKIVSNKLDTRIFDFGFDVLSIKYVDEQDLYDLLELRVSKKEDWIDILSSIKNSTEINKPAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBA6</accession>
    <name>A0A5C6ZBA6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20805</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000131">
        <property type="protein sequence ID" value="TXD85766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002686">
        <property type="entry name" value="Transposase_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036515">
        <property type="entry name" value="Transposase_17_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM01321">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143422">
        <property type="entry name" value="SSF143422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Y1_Tnp" evidence="1">
        <location>
            <begin position="8"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD85766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="176" mass="21238" checksum="68BB91A13A687E6F" modified="2019-11-13" version="1">MLLKPIKIEDCPQFFTATILDWKMLLRPDKYKLVIIESLKFLVDENRVIVYGYVIMDNHLHIIWKPTPLFSLKHTQLSLMKFTAQRFKRDLELNHPNVLQYFLVNSKDRDFQFWQRNALCVDLYSNRILEEKLQYIHRNPLKAGMGSDGNFYRFSSEKFYRELGDEFEFLTDFRQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBE6</accession>
    <name>A0A5C6ZBE6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">GntR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_19815</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000048">
        <property type="protein sequence ID" value="TXD86599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_006988392.1">
        <property type="nucleotide sequence ID" value="NZ_VORO01000048.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="4">
        <location>
            <begin position="5"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD86599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="202" mass="23320" checksum="EE861F87E70E8FCF" modified="2019-11-13" version="1">MITKITYRNQVRELILDKMKTGELKAGESLSLASIARDLEVSVTPIREALTQLEQSRIIKSAPNRGFIIPELNNVIAKDLYQLVATLESLAIENSVYSKSIIKKLKKQQEKIETSNNAIDRVNEDIIFHNILTSQYKNETAQQILLDLKTRIFFYELEFMSLDNSLNQQHNQIINYLENGQIKDAVKILKLNWLQVLDFLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBJ5</accession>
    <name>A0A5C6ZBJ5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Proline dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_20540</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000085">
        <property type="protein sequence ID" value="TXD86187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004657">
        <property type="term" value="F:proline dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006562">
        <property type="term" value="P:proline catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029041">
        <property type="entry name" value="FAD-linked_oxidoreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002872">
        <property type="entry name" value="Proline_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015659">
        <property type="entry name" value="Proline_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13914">
        <property type="entry name" value="PTHR13914"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01619">
        <property type="entry name" value="Pro_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51730">
        <property type="entry name" value="SSF51730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pro_dh" evidence="2">
        <location>
            <begin position="79"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="393" mass="45778" checksum="2951E601B1BED8AA" modified="2019-11-13" version="1">MTEHHLFENTKTAFSLKRDSELQRAYLLFKMIGYAPLVKIGTMVTHFALKLHLPVEGLIRYTVFDHFCGGINEEDCNDVIDAMYTKGVSSVLDYSVEGKAIESHFDAAAEKIMKIIKFADEKEAMPISVFKPTGFGRFYLYQKKGEGKTFTTEEQLEWERVIDRYDRVCKLAEERDVEVLIDAEESWMQDAADEICEEMMRRYNTKVPVVYNTLQTYLWDRLDYLKKVHQRAKQHNFKPGFKVVRGAYMEKERERAEEKGYASPICENKKATDDNFNACVQYILEHLEEISIFIGTHNEFSCYIAMDMMRTLNIDKKDNNVWFGQLYGMSDHISFNLAKEGYNVAKYVPFGPVREVMPYLIRRAEENTSVAGQTSRELNLITTEQARRKSENK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBK2</accession>
    <name>A0A5C6ZBK2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20575</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000089">
        <property type="protein sequence ID" value="TXD86142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022899925" evidence="1">
        <location>
            <begin position="19"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="219" mass="26327" checksum="7CF866F0939A2A96" modified="2019-11-13" version="1">MKKILIILLIGISNIAFSQTMKEIDSVSYVMCDYLKNLEIKNDTLKINSLYEKQLYPYLGKFEQSKTQKIGQQVYYRLQRNCVEFRNLLDRLEPPREEVIRITEKPKSEISKKQLKEFKKQREFYYFEVAGDTTKVIMENGKWTDSFSNKTFSKLTYNWINETEFELVFIESDNETRSNFSVIGDKYIYQILSKEDEFYLMTVNILGQKTFEKFKMYYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBM6</accession>
    <name>A0A5C6ZBM6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17785</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000028">
        <property type="protein sequence ID" value="TXD87166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase" evidence="1">
        <location>
            <begin position="42"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="550" mass="63101" checksum="A7A4D08732AEDEDF" modified="2019-11-13" version="1">MKNKNGMIIILLFIAGNIFGQTKLSENQLKKLDSIATQDVPKNAPGIATAIIKKGNLIFEKYAGIADFKDSLKIDKHTRFNIASNGKQFTALAILTLEDDNKIKLSDDIRQYLPDLYPEIKSKITIGNLLNHSSGIRDVYDLWSLKGLTWWEYSFNNNDVLELIKKQEALNFEPSSKYVYSNTNYILLAIIVEKISGKTFKEYTDGIFQKLNMPNTSFEADYSQIDGKIARAYFNFDKWTTYDWVWNVVGDGNLFSTLTDQIQWEKTIQGYGKSRIKNSIIQKSQELVNQDANDNYGFGLEFGEYKGLKYKFHEGATGAWKATVIRFPKDGISMLTLTNSGKSIPSMQTRQMADVVFDLKKDAKYLVTKPSNIGKYINEDEIIGTYITPNNFTFEFLKKDDGKLYLKRIGRSDIELIREFDNIFNQKFDKDFKQEFIENENGEMQVTAYYTNHSPYTLTRKKSDWKDYGYQALNGKYNNSETDVNIEISYLSNKDYKVLIGDQENSGLLIAPTKLMVNNYVFEFANGTNVVESLSLNTDRIIGVNFERLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBN3</accession>
    <name>A0A5C6ZBN3_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">1-deoxy-D-xylulose-5-phosphate synthase</fullName>
            <ecNumber evidence="8">2.2.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">1-deoxyxylulose-5-phosphate synthase</fullName>
            <shortName evidence="8">DXP synthase</shortName>
            <shortName evidence="8">DXPS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">dxs</name>
        <name evidence="10" type="ORF">ESY86_18360</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>D-glyceraldehyde 3-phosphate + H(+) + pyruvate = 1-deoxy-D-xylulose 5-phosphate + CO2</text>
            <dbReference type="Rhea" id="RHEA:12605"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57792"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
        <text evidence="8">Binds 1 thiamine pyrophosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Metabolic intermediate biosynthesis; 1-deoxy-D-xylulose 5-phosphate biosynthesis; 1-deoxy-D-xylulose 5-phosphate from D-glyceraldehyde 3-phosphate and pyruvate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 8">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the transketolase family. DXPS subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.7" evidence="8"/>
    <dbReference type="EMBL" id="VORO01000031">
        <property type="protein sequence ID" value="TXD87023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00064">
        <property type="reaction ID" value="UER00091"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008661">
        <property type="term" value="F:1-deoxy-D-xylulose-5-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052865">
        <property type="term" value="P:1-deoxy-D-xylulose 5-phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016114">
        <property type="term" value="P:terpenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02007">
        <property type="entry name" value="TPP_DXS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00315">
        <property type="entry name" value="DXP_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005477">
        <property type="entry name" value="Dxylulose-5-P_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020826">
        <property type="entry name" value="Transketolase_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43322">
        <property type="entry name" value="PTHR43322"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13292">
        <property type="entry name" value="DXP_synthase_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00204">
        <property type="entry name" value="dxs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00802">
        <property type="entry name" value="TRANSKETOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0784">Thiamine biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="4 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Transket_pyr" evidence="9">
        <location>
            <begin position="283"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Thiamine pyrophosphate binding" evidence="8">
        <location>
            <begin position="116"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Thiamine pyrophosphate binding" evidence="8">
        <location>
            <begin position="148"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="176"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="334"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD87023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="598" mass="65264" checksum="57F3553A07C65A29" modified="2019-11-13" version="1">MEKPYLKYIDAPEDLRTLPFEQLPELAAELRQFIIDIVSTKEGHLGASLGVVELTIALHYVFNTPEDLLIWDVGHQAYVHKILTGRKTVFETNRQKGGISGFPKITESAYDAFGVGHSSTSISAALGMAMASQLQGKDLCHIAVIGDASIASGMAFEGLNHAGATDANLLVILNDNAIGIDPSVGALKQYLTNVKKGKAKQDNIFEALNFNYSGPIDGHDLTELISALKHLKTVKGPKFLHVITTKGKGLKQAEEDQVKYHAPGKFDALTGDLLPKSGLKQPSKFQDVFGHTLVELARLNEKIVGITPAMPTGSSLKYMMQEMPNRAFDVGIAEQHAVTFAAGMATQGLMPFCNIYSTFLQRAYDQVIHDVALQNLAVIFCLDRAGFVGEDGATHHGIFDMAYLRCIPNLIIFAPSDEIELRNIMFTAQLGLESPIAIRYPRGRGQLMDWQVPFSKIEIGKARPLHEASDKKIALLSIGTMAFPSSKAVLKCSDAAVSHYDMRFVKPLDETLLHEIFKSYEAIISVEDGVIAGGFGSAILEFASKNEYHLPITCLGIPDVFIEHGSVEELHQAVGLDVESIANTLHALLLNLNQNQTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBS2</accession>
    <name>A0A5C6ZBS2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20440</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000074">
        <property type="protein sequence ID" value="TXD86288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="165" mass="19440" checksum="2C7E664AFA38BCDE" modified="2019-11-13" version="1">MESLFKKLKLIDSLEFEYDIEPKEFQKRIKLIVDEETPILLDELYRSKKIFCGKVGDKKFTLRKKRKFMNLNIQSSNAVGIISVVNQKTKLNVKIFGYDEISTLAIIVGPIFFLILFYVIITKEAYPALILFVPIATLILIFPYYIMKKNMKIFRIELKENLKFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBW9</accession>
    <name>A0A5C6ZBW9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">TerB family tellurite resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_17715</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000027">
        <property type="protein sequence ID" value="TXD87272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029024">
        <property type="entry name" value="TerB-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158682">
        <property type="entry name" value="SSF158682"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="133" mass="15743" checksum="D396218F489FBAC9" modified="2019-11-13" version="1">MINRVEKLSLLSEMISFAQTDDKIKSIEYKFLFSISKQLEIPKADFDYLFEHPVTYVHLKSHSERIVQFHRLVLLMNLDQAITNRELVKLHNFGLRMGLGHECINRVLYVMESFPNKIVPPDFLIDIFKVQYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC82</accession>
    <name>A0A5C6ZC82_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Carboxypeptidase-like regulatory domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19580</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000043">
        <property type="protein sequence ID" value="TXD86692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="875" mass="101549" checksum="29C0B623A0CFEE7F" modified="2019-11-13" version="1">MRNYICLMHILFNCFVFSQDYKINGNLYSVENTPITNAIIVVYQGGKIVAYTYSTSNGSYEATFKLNNVNLTNLKIVANGLGYQHQEKSVSIKKKSAVTVDFTLVKKIEQLDEVVIEAWEKIKVKRDTITYKVSAFRDGSESVVEDLLKNIPGIEVSSDGNIKVNGKSIDKLLIEGDDLFDDKYKLLTKNLDANNIEEVEVLNNFEDNPVLKQFQDSEKVALNLKLKADKKNVWFGNIDLGTGYNKRYNTTANIGLLKKKIKLFNLSNLNSIGNTAISQVKNTGIIDFNSLAADKKNEKTNNEFVNIDNLSSSNFSNNEDIFNNSFLNSLSFVTHLSKQTKLRSLTYFTYDDVNKQNNNLTEYFIEPETISFTEQNTIDIKDISFATELELKHYSKNETYFTYDFTFENNPTETRGNLIFNNDNINQLQDDKRHNLFNHLNITKKISDKTLLLTYAYLGINNTHQNYTIEPNIFSDIFNNNENSTIKQNSKTPLSYYGIISEFVAKGIKSEYGFEFSATVDKDKIESQFKFDNQTAIDTLTNNLDYKNSRLAITSKYNYNISRLFKISSSLKISQNYIKLNDSKQQFFFVNPKIRFHTKKTKIGNFGISYGFQNNLPQSKYLTENFILTNYRTFNRGLDNIQQINNHSFGFYYTFNNYKKQFLINSFLMHSFSDKSYGLNSLLSENANFNQYQIIDGGKLTNYNLSITRYLKALSSTLKLSTQQFWSRNPIILNNTISEVINYNSNYRIQGTTYFKIPLNFKFGFQYNYSKGEFDSQISSNNYIESNLDTTLKLSDKWFFKIENNFYSIIENNYLFVNANLNYNPENSRFSYRISANNLSNITEFKDVFISEFQRNETNFRILPRYLIMNVKYRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCD9</accession>
    <name>A0A5C6ZCD9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nuclear transport factor 2 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17625</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000027">
        <property type="protein sequence ID" value="TXD87254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022780075" evidence="1">
        <location>
            <begin position="24"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="172" mass="19318" checksum="793B5BBC8A520B7F" modified="2019-11-13" version="1">MKTLKTSAIVLFLIIGQITFAQAKSYKETVTENPTAEEDLKVVGDYLDALINNNMDKAASFIADSYVGTGPDYQETETKAEHIAGWKEAHKSRKNEKNDYISQTFRVIDGDLKGDWVSVWGTYTFTENDVTVNLPYQYTAMVDNGKIVQSVIYYNRLAVSTAMGYELTAKQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCF2</accession>
    <name>A0A5C6ZCF2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Class I SAM-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_16965</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000024">
        <property type="protein sequence ID" value="TXD87469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="256" mass="29202" checksum="5FB39128F5C20FE6" modified="2019-11-13" version="1">MFQYFQYLKFLSASTNQHGVHSPFVYDLVTKCFYDSSNYGAYEQLSAYRNALLSDQKSIAINDFGAGSKVFKSDTRVVSQMAKHSGSTLKRAKLVFRLVKYLQPKTTLELGTHLGIATQALALGASGNQVVSVEGCAQTSEMAKTQLKHFGIDNVSLKTGRFEDLLPQLKQQNYDLIFFDGNHSKSATLHYFEELLETTHNESVFIFDDIHWSKGMNEAWELIKRHPKVSVSIDTFFWGLVFFRSEQEKQHFKIRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCN2</accession>
    <name>A0A5C6ZCN2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CPBP family intramembrane metalloprotease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000028">
        <property type="protein sequence ID" value="TXD87201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="201"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="221" mass="24818" checksum="941FE17582093EC5" modified="2019-11-13" version="1">MLTILLGYVLFIIPDIFFGVTKINGGKIGINLLWIALFQFLSILALLYASLKILKKDFSYIGLKFVNVKKDFLLGLIFGTLWTILQFVLIIPNTGGINRPDINGMLEMYDGSLIGTLSFIALGVIGGGITEELFNRGYFISVLKDVFKKPKLGLWFSAILSIVLFSLGHMPVSALDWFDILIPTIMYTFLFITTKRLTASIVAHGIYNMTAIILTYYLYFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCQ0</accession>
    <name>A0A5C6ZCQ0_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ribonuclease Z</fullName>
            <shortName evidence="8">RNase Z</shortName>
            <ecNumber evidence="8">3.1.26.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">tRNA 3 endonuclease</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">tRNase Z</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rnz</name>
        <name evidence="10" type="ORF">ESY86_17140</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>Endonucleolytic cleavage of RNA, removing extra 3' nucleotides from tRNA precursor, generating 3' termini of tRNAs. A 3'-hydroxy group is left at the tRNA terminus and a 5'-phosphoryl group is left at the trailer molecule.</text>
            <dbReference type="EC" id="3.1.26.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8">Binds 2 Zn(2+) ions.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1 8">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the RNase Z family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.11" evidence="8"/>
    <dbReference type="EMBL" id="VORO01000025">
        <property type="protein sequence ID" value="TXD87394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042781">
        <property type="term" value="F:3'-tRNA processing endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07717">
        <property type="entry name" value="RNaseZ_ZiPD-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01818">
        <property type="entry name" value="RNase_Z_BN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013471">
        <property type="entry name" value="RNase_Z/BN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02651">
        <property type="entry name" value="RNase_Z"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6 8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 8" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="7 8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Lactamase_B" evidence="9">
        <location>
            <begin position="19"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="64"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="210"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="268"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD87394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="301" mass="33926" checksum="E3E8AA00DF2CB2A4" modified="2019-11-13" version="1">MKLTILGCHSATPRINSNTTSQVLEIKNHTFLIDCGEGTQVELRRNKIKFGKIMHIFISHLHGDHVFGMAGLISTLNLLTREKDLHIYAPKGLKEVITLQMKLAASWTSYQLVFHELSSNTSELIFEDDQVEVHTIPLDHRVYTNGFLFKEKPGERKLDINAVKKADIEVAYYQKIKQGFDVVNKKGQLIANNALSKAPNPPKSYAFCSDTAYSERIVPIVENVDMLYHESTFLEKNSDLATKTKHSTAKQAAQIALKAKAGLLILGHYSTRYGDFKVFQEEAQGIFKNVELAEDGKQFEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCS8</accession>
    <name>A0A5C6ZCS8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF262 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_19020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000036">
        <property type="protein sequence ID" value="TXD86869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004919">
        <property type="entry name" value="DUF262"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03235">
        <property type="entry name" value="DUF262"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF262" evidence="2">
        <location>
            <begin position="52"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="12"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="366" mass="43031" checksum="E3016E4E78DFC98C" modified="2019-11-13" version="1">MDDNITEEEKDLLELENEKSFEDDSSSDLPPNDIVAFNELRSCSDLVRMYRTKQLEIQPDFQRDIVWSKPSQTRFIDSLIKQLPIPSICISLDYKTNKRLVIDGLQRMQSIINFLTDEEWKLSKLTDIDDKISGKSVAVIKNKYSDIYERVENLTIPVTVLRCDYSKRSHMKYLFTIFHRLNTGGLKLNNQEIRNCIFNGKLNALLKETVKYENFRKLLNLQKDKTYRFNYEELILRFFALYDNLDEYNGKLAVFLNEYMDNNKNPDDEFLASKRHLFERTVDLLYIKILESEKIPNISKATIEGLLIGISKNIEQLEQLERDTVVERYRALRGDDLFSIDSLKEGLSQKDKVVNRLERAEEVFNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCW8</accession>
    <name>A0A5C6ZCW8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Endo/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_15915</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000021">
        <property type="protein sequence ID" value="TXD87646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="Endo/exonuclease/phosphatase" evidence="2">
        <location>
            <begin position="122"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="331" mass="37950" checksum="13BEFB9DCFDB38C2" modified="2019-11-13" version="1">MKTLKKILYIVLIVIAVFLAVCSILSVLRNTESRFLKILDFPRIQFFVASFICLLILVAAIKKWKWYDYLLSAGLLAGLIINGSYLIHYTQLVPVSVPAAINIKASDAQMSLLITNVKMTNRQAQPLIDLIELKDPDLILAMEVDEWWDNELQVFKKDYPYSQHTINELTYGMVLYSKLPLKKIEVDYLNNENVPSFESSITLPNGKNIRFHSIHPVPPTRFKNLPDNANQQETALIKLGTEITGRTSPTIVAGDLNDVVWSHVDKLTNTKNLLYDVRVGRGFFNSFNAENLLMRWPLDHIFVTEEFRLKKLERLTKIGSDHFPIYVELVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD55</accession>
    <name>A0A5C6ZD55_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Putative tRNA (cytidine(34)-2'-O)-methyltransferase</fullName>
            <ecNumber evidence="1">2.1.1.207</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">tRNA (cytidine/uridine-2'-O-)-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_16350</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Could methylate the ribose at the nucleotide 34 wobble position in tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>5-carboxymethylaminomethyluridine(34) in tRNA(Leu) + S-adenosyl-L-methionine = 5-carboxymethylaminomethyl-2'-O-methyluridine(34) in tRNA(Leu) + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:43088"/>
            <dbReference type="Rhea" id="RHEA-COMP:10333"/>
            <dbReference type="Rhea" id="RHEA-COMP:10334"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74508"/>
            <dbReference type="ChEBI" id="CHEBI:74511"/>
            <dbReference type="EC" id="2.1.1.207"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>cytidine(34) in tRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(34) in tRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:43084"/>
            <dbReference type="Rhea" id="RHEA-COMP:10331"/>
            <dbReference type="Rhea" id="RHEA-COMP:10332"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74495"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.207"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.207" evidence="1"/>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008175">
        <property type="term" value="F:tRNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd18094">
        <property type="entry name" value="SpoU-like_TrmL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01885">
        <property type="entry name" value="tRNA_methyltr_TrmL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016914">
        <property type="entry name" value="tRNA_cyt/urid_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42971">
        <property type="entry name" value="PTHR42971"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029256">
        <property type="entry name" value="SpoU_TrmH_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="SpoU_methylase" evidence="3">
        <location>
            <begin position="3"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1 2">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1 2">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1 2">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR029256-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD87603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="150" mass="17125" checksum="8402342DA8AAA50B" modified="2019-11-13" version="1">MPLNIVLIEPEIPNNTGNIGRLALASGSRLHLVKPFGFEISDARLKRAGLDYWKHLDIQYYDSSEAFFSKHKNANMAFFSSHGHKSHWEIPFAEEQFLIFGKESVGLPKSLLESQRDLLYKIPLFSEHIRSLNLANSVGIVVYEGLRQLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD73</accession>
    <name>A0A5C6ZD73_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000054">
        <property type="protein sequence ID" value="TXD86517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13304">
        <property type="entry name" value="AAA_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase_AAA_core" evidence="1">
        <location>
            <begin position="46"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="427" mass="49915" checksum="2A559BD3B01ADB95" modified="2019-11-13" version="1">MLLEFKIKNFRSIKDWQSFSMLGESKVKELENSLIDHNGYKVLSSAIIYGRNASGKSNLLKAFKMIQYMVIFSDDFKVDDKIDYYEPYKLDKNFRNEPVEFLIDFIGKDGIRYEYGLGYSSEEIVYENLRFYPKSQPAWLFRREKGEKIKYGESLTGNKKNIEELLYKNQLFLSKIGTEKNKQLAIPYSFFSKYLYVSDVHDTSYDNVLIQLFTNKMGKDNIPFFKENINKLMCVADTGIQSINIEESEINLDGLPKEMTDEDKNELRERYKYKIRTLHREFENGKEIGNIEFHLGDESTGTLKLLAVGGLILEALADGQTLVIDELDKSLHPKLTRMLIRIFRSPKLNPKNAQLIFATHDVSLLDNELFRRDQVWFAEKEFEGNSHYYSISDIPGVRGNVPYEKWYMTGRFGATPVINEHELDFHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDA1</accession>
    <name>A0A5C6ZDA1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF5103 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_16530</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000023">
        <property type="protein sequence ID" value="TXD87500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031345">
        <property type="entry name" value="DUF5103"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17116">
        <property type="entry name" value="DUF5103"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="416" mass="48473" checksum="238F34EFD0FD0E1C" modified="2019-11-13" version="1">MKLTFKILSLILIFPLFLAAQVFEVNPPDFIKTISFRGNTQVSKLPILNLGDPLFLEFDALNGEEADFYYIIEHYNFDWTPSQLVKMEYLSGFDNQRIRDYENSFNTFQIFSHYTLRIPNQQTRGLLKSGNYLISIYNDDQELMFSRKFMVVEELVAVGVDIKRSRDVKFIDEKQSVDIIINTNSINLNNPQNTIKTLLVQNNNLNTAIDYLKPQFILGNELVYRYVEKSTFWGGNEYFFFENKDVRASNVSVQFTDLRDLYHSFLFVNGARADRPYTYNPDINGNFLINALDVDDLRLEADYTVVHFGLQYPKFTDGSNIYVYGNFNNFGLEPMNKMIFNAAEGIYESQFKLKQGFYNYKYVVVDKSGELNEGHISGNFWQTENNYKVLVYYRDLGARYDRLIGFGEANSINISN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDN6</accession>
    <name>A0A5C6ZDN6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_17925</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000028">
        <property type="protein sequence ID" value="TXD87193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="220" mass="25405" checksum="F97F79C903A89857" modified="2019-11-13" version="1">MDNPSKITEGGVEYSLGKFDGKSVLYDFDQILIYLNAKGKLLFGKNFRIYDEDTVIIRKLCYYFIKDKENCQKEGIDPDKGILLSGPVGCGKTTLMKLLRHIVPMQRPYEMIPCRNVAFSFNHLGFKTIEEYGSTKFFCFDDLGVEPAGRFYGKDLNVMGEVLLSRYELYLKTKHKIKTHATTNLNAEELEERYGNRVRSRMREMFNLIAFDKGAGDKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDR4</accession>
    <name>A0A5C6ZDR4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Branched-chain-amino-acid aminotransferase</fullName>
            <ecNumber evidence="15">2.6.1.42</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">ESY86_17490</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>2-oxoglutarate + L-isoleucine = (S)-3-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24801"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:35146"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 15">
            <text>2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:18321"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:17865"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 15">
            <text>2-oxoglutarate + L-valine = 3-methyl-2-oxobutanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24813"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4 14">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 4/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 4/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8 13">Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.42" evidence="15"/>
    <dbReference type="EMBL" id="VORO01000027">
        <property type="protein sequence ID" value="TXD87229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00058"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00073"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00062"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052656">
        <property type="term" value="F:L-isoleucine transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052654">
        <property type="term" value="F:L-leucine transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050048">
        <property type="term" value="F:L-leucine:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052655">
        <property type="term" value="F:L-valine transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01557">
        <property type="entry name" value="BCAT_beta_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018300">
        <property type="entry name" value="Aminotrans_IV_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005786">
        <property type="entry name" value="B_amino_transII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033939">
        <property type="entry name" value="BCAT_family"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11825">
        <property type="entry name" value="PTHR11825"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006468">
        <property type="entry name" value="BCAT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="SSF56752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01123">
        <property type="entry name" value="ilvE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00770">
        <property type="entry name" value="AA_TRANSFER_CLASS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 15 16" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="15" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="11 14" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 15 16" id="KW-0808">Transferase</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="12">
        <location>
            <position position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00004931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00005072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00009320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR006468-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU004517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="TXD87229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="356" mass="39954" checksum="EA98FE79C229DABA" modified="2019-11-13" version="1">MSNTANAKLQIEKVKESRVSSIDFSDLAFGKTFTDHMFYCDYKNGAWQEPKIVPYQPMTIDPSARVFHYGQAVFEGMKAYKDDNGKVFLFRPDQNFKRINKSAARLAIPEFPENYFFEGLKTLVNMDKAWIQPGVGNSLYLRPFVIAIDSAIAAAPSESYRFMIICAPAKAYYKGTVRVLIAEKFSRSASGGVGFAKAAGNYAAQFYPTKLAQDRGYQQVIWTDADTHTYLEEAGTMNVFFRINDTLITAPISDRILDGVTRKSLIQLAADNDIPCEVRPIKVSEIVEASKDGSLKEIFGAGTAAVISPISAFEFQEQVYELPEVNEHSYSSRLKSKMLNIQHNLAEDKNGWRMEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDU6</accession>
    <name>A0A5C6ZDU6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4136 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_14445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025411">
        <property type="entry name" value="DUF4136"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13590">
        <property type="entry name" value="DUF4136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4136" evidence="1">
        <location>
            <begin position="29"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="194" mass="22446" checksum="1D2A588EAA6FC31B" modified="2019-11-13" version="1">MKLRLIYSILAIVMISCGPKVNTAKLVDKDLSNYNSFAYLPNSNFDDLKKFETDPTVGTAIIESVNRNMKQKGYELDRNNPDLLVLLSTMTDKERTVDQEPVYATYPNNYGRSYGVSPYYQNQYYYNYSSYSRIIGYERDIDRYKEGTLLIRLVDSDSKEVVWRGSASDAIFKQNETTAIAKFVDDMFDDFPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE16</accession>
    <name>A0A5C6ZE16_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Leucyl/phenylalanyl-tRNA--protein transferase</fullName>
            <ecNumber evidence="4">2.3.2.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">L/F-transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Leucyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Phenyalanyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">aat</name>
        <name evidence="5" type="ORF">ESY86_13840</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>L-leucyl-tRNA(Leu) + N-terminal L-arginyl-[protein] = H(+) + N-terminal L-leucyl-L-arginyl-[protein] + tRNA(Leu)</text>
            <dbReference type="Rhea" id="RHEA:50416"/>
            <dbReference type="Rhea" id="RHEA-COMP:9613"/>
            <dbReference type="Rhea" id="RHEA-COMP:9622"/>
            <dbReference type="Rhea" id="RHEA-COMP:12672"/>
            <dbReference type="Rhea" id="RHEA-COMP:12673"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:64719"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78494"/>
            <dbReference type="ChEBI" id="CHEBI:133044"/>
            <dbReference type="EC" id="2.3.2.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>L-leucyl-tRNA(Leu) + N-terminal L-lysyl-[protein] = H(+) + N-terminal L-leucyl-L-lysyl-[protein] + tRNA(Leu)</text>
            <dbReference type="Rhea" id="RHEA:12340"/>
            <dbReference type="Rhea" id="RHEA-COMP:9613"/>
            <dbReference type="Rhea" id="RHEA-COMP:9622"/>
            <dbReference type="Rhea" id="RHEA-COMP:12670"/>
            <dbReference type="Rhea" id="RHEA-COMP:12671"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:65249"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78494"/>
            <dbReference type="ChEBI" id="CHEBI:133043"/>
            <dbReference type="EC" id="2.3.2.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>an N-terminal L-alpha-aminoacyl-[protein] + L-phenylalanyl-tRNA(Phe) = an N-terminal L-phenylalanyl-L-alpha-aminoacyl-[protein] + tRNA(Phe)</text>
            <dbReference type="Rhea" id="RHEA:43632"/>
            <dbReference type="Rhea" id="RHEA-COMP:9668"/>
            <dbReference type="Rhea" id="RHEA-COMP:9699"/>
            <dbReference type="Rhea" id="RHEA-COMP:10636"/>
            <dbReference type="Rhea" id="RHEA-COMP:10637"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78531"/>
            <dbReference type="ChEBI" id="CHEBI:78597"/>
            <dbReference type="ChEBI" id="CHEBI:83561"/>
            <dbReference type="EC" id="2.3.2.6"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the L/F-transferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.6" evidence="4"/>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008914">
        <property type="term" value="F:leucyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3550">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00688">
        <property type="entry name" value="Leu_Phe_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004616">
        <property type="entry name" value="Leu/Phe-tRNA_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042203">
        <property type="entry name" value="Leu/Phe-tRNA_Trfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042221">
        <property type="entry name" value="Leu/Phe-tRNA_Trfase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30098">
        <property type="entry name" value="PTHR30098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03588">
        <property type="entry name" value="Leu_Phe_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00667">
        <property type="entry name" value="aat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD88176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="208" mass="23209" checksum="09B97406AF64A06D" modified="2019-11-13" version="1">MVFLDETLSFPHVSQASAEGILAIGGDLSPERLVLAYKSGIFPWFDSDEPILWWSPNPRFVLFPEQLKVSKSMKQVLRNANFELSVNHDFEQVIDTCSKMKRAGQPGTWITNTMKAAYLKLHELGYAKSVEVWQNGELVGGLYGVDVGNGLFCGESMFAKVSNASKVGFISFIQNSEYKLIDCQVYTNHLASLGAKDIPRAAFLKYLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE42</accession>
    <name>A0A5C6ZE42_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CHAT domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000025">
        <property type="protein sequence ID" value="TXD87383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008374">
        <property type="term" value="F:O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003386">
        <property type="entry name" value="LACT/PDAT_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02450">
        <property type="entry name" value="LCAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHAT" evidence="1">
        <location>
            <begin position="1169"/>
            <end position="1445"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1769" mass="199832" checksum="2418132AA2EB617C" modified="2019-11-13" version="1">MIKTAKLYGNDITLSHTETALPEGLNDKFRLKRSIEVAATRSENKPIIIEFEDDDLLAIHFTDNTEWIGHPEDIQELYGKSVLENRSGKQEDYLFETQITADNQTRGFVSRAVVKLFSVFSTKAVAKVSMTQLGKSYDQKVQPHPGLYQLNADFKLEPFKKTAKTHYLLFLHGTLSTTIDAFSGLKSTGVWQEMQLLYGSNIIALEHYTLSQSPLQNALDFLLACPDDCTLDILSHSRGGLVADILAKCDHRNFDTQVGFSENELSIVYKEDKVSHKLMLSINELVISKRIKIVKIVRVAAPASGTTILSRRVDHFFNLLLNAISLAFGIRNPMYEYVKSFLLELINQKEDPEVLPGLNSMMPESVFQNMMNAADTAVVSDLFAITGDADASGINLDSLKVILANLFYQAANDLVVDTRRMLHGVQRRDGIYAFPSKGSETNHFKYFSNSNTQNAILEALLASENKPALSYTKMVHSAADRGVVLDLFSMDGFSLKPKNITRDVVIIVPGIMGSTLATNNEDRWVSFSNLNKGTIASDLNISATNVEASGIIKKYYAKMGAHFEANHDVITLEFDWRKSVKSAAVALKELLDSLSQLSIGVNIVAHSMGGLVVRQCMMSHKPTWELFSKNKNNKFIMLGTPWLGSYLIMEVLTGHSKRVKQLAAIDFKNSKKDLLKIFWKYPGVFELMPIEMHSKRAFWETQFWDELNEKAKLEVMPPAEKNTRALKDFEDFRTEVISFLDHLDKEDNDGFFKNIFYICGKANETVFDYTFKSRFLSKNEKLVYKATSYGDGSVTWQSGIPKQLKGSKNLYYANTSHGDLANETYIFEGIADIITSGSTLKLSANSPASRSGEIISEVHEYAEPLGNKTAVLDAIFNVEQPTEPVAELITVTVVNGDLKVASYPVLVGHFYMDMILSAEKALDGYLNNRLSQRLDIGYYPGRVGESEVFFNLKTQPKGAIVCGMGDSDKLTTFLVAKTVKMATLKYAMFMRDNYTLPEAKRYANGISVILIGIGYGKLPIEDSIKGILLGVSAANTYIKEKGEGLKLIKDIEVINYYESIASQAYFSLNRIKDNDNRILINLKKGILRRTGAKKKQLFGDSQYNWWYNLHINSIVKQAETTTEPNKVVGFNYYATNGTARVEQEMIGIGLDRINLLLEDKAYQFIWNKRLSKTLFEMLIPNDFKDIFRNQTNMIIKMDRQSAQLPWELLHDPETDETPASVSSSFIRQLVAESPDDFDKVALSNNNAFVVGDPLYENENLPQLPAAKAEAEWLNGQLTRFGFTSNVLLNSTATTIMMELFNKDYKIMHFSGHGLYAPEKGEVGIAIGNGICIDPAMIKQLGYVPEFVFINCCYSGAVNAADDNYSKQRYKLAANVGTQLIEMGVKAIVISGWAVDDAAAKTFAEAFYNKMFEGYNFGMAVQKARMACYQLHKSTNTWGAYQCYGNQFYQFDSRMKTKKEDLEYVISSQVYTDLDNLLIAIRDQKYNTVATLTKLEFYLEKVQNANLLDASVLEKEAMIYNELGYSEIAYQKFKDLFQYTSGNFSIEALEQYCIIKTNRIQKETLLEDLHEIEFLTLIGKNPSRLNIVGNAYKIASKLLDTNKERIEYLKKAFTFYEDSYKASSDPYSGEALDAMSNLIFIGHILELLGDDKLLDRINKSNAFESIVDVKTYLQDFHQELESFDKTDLDVSVLIGMAEANYGLMLLDSKFKPSIEIEIIDRFKHVFRLLYSPRYIKYEIIQIEFLLFYIKDEVIKKQLEAIKLEVQQLLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE44</accession>
    <name>A0A5C6ZE44_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Response regulator transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_13995</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="7"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="133"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="133"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD88206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="227" mass="25745" checksum="3819E692A33C3C1A" modified="2019-11-13" version="1">MKKTDIKILLVDDEPDILEIVGYNLINEGYKVITAKNGLEAIKMAKAELPQLIILDVMMPKMDGIEACENIRKIPELAETLIAFLTARGEDYSQMAGFDAGADDYITKPIKPKVLVSKVKGLLRRLKEDVVKEDIIKVGNLVINREEYKIILKGKEIILPRKEFELLSLLATKPNKVFKREVILDKVWGNEVVVGGRTIDVHIRKLREKIGDKRFKTIKGVGYKFVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEI5</accession>
    <name>A0A5C6ZEI5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">4-hydroxythreonine-4-phosphate dehydrogenase PdxA</fullName>
            <ecNumber evidence="3">1.1.1.262</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pdxA</name>
        <name evidence="3" type="ORF">ESY86_13055</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.262" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050570">
        <property type="term" value="F:4-hydroxythreonine-4-phosphate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005255">
        <property type="entry name" value="PdxA_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30004">
        <property type="entry name" value="PTHR30004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04166">
        <property type="entry name" value="PdxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00557">
        <property type="entry name" value="pdxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="348" mass="38448" checksum="E72077926D14544F" modified="2019-11-13" version="1">MEKDKNIRVGISIGDLNGIGSEIILKTFEDSRMLEFCTPVIFASIKTMSFFKKHFNSSINFHGINHLNQIVDGKINVLNVWKENVSINFGEEDVEIGAYSVKSLETATAALISEDIDVLVTAPIHKHNIQSESFKFPGHTNYLAEKLGGKSLMFMVTETLKVGLLTDHVPLKDASAQITAALISEKIDTVYTSLIEDFAIERPKIAILGINPHAGDNGVIGTEDDSILKPELEKLRNKGKLVYGPYAADSFFGSKNYKNFDAIIAAYHDQGLIPFKTISFGHGVNFTAGLNKIRTSPDHGTAFEIAGKGEADHGSFKAAVFMAMDIFKTRTNYKIYSKNPLKKRQKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEK0</accession>
    <name>A0A5C6ZEK0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Restriction endonuclease subunit S</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_17760</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-I restriction system S methylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000028">
        <property type="protein sequence ID" value="TXD87162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.220.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000055">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044946">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01420">
        <property type="entry name" value="Methylase_S"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0680">Restriction system</keyword>
    <feature type="domain" description="Methylase_S" evidence="4">
        <location>
            <begin position="19"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="Methylase_S" evidence="4">
        <location>
            <begin position="240"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD87162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="425" mass="49256" checksum="344DEEB724D43453" modified="2019-11-13" version="1">MTKYETYKDSGVEWIGAIPEHWEVKKIKHFCYVKGRVGWKGLKSSDFLQEGYAYLVTGRDFKTNRIDWKKSYHIDKERYEEDPYIQLENNDLLITKDGTIGKLAIVENLDKPACLNSGIFVVRSLDEHLLTQYLYWVLFSDVFKKFNGYTTYGSTIQHLYQNVFVDFAYPLPSNISQEKIANYLDKKTAEIDDLIGQKKQLLKLYEKEKEVIINQAVTKGINPDVKLKDSGIEWLGAIPAHWEVKKLKYVLASRNHKRIPLSSSERGEMMSKKYDYYGASGVIDKVEDYIFDEPLLLIGEDGANLLTRSKRLVFIAKGRYWVNNHAHILKPKYGLIDYYSELLELYDFSIWVTGSAQPKLTSENLLNIPMVVPPIEEQNQISEFLMKKIWEITQKSENIKKLIALLKEYKTALISDVVTGKIKVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZET2</accession>
    <name>A0A5C6ZET2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_13545</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="445" mass="50280" checksum="30621A9092FA76FD" modified="2019-11-13" version="1">MKGYTHTFLVLSFILVIFPAMKGFSQNEFGNSNLRLYLDDNKEHWLQFSSFVQLWSRVTENNPGTTVNDVPEAVTSDISIRRFRLGLAAKPADKVFVFFQLGVNNLNYLSPRGTSIDLLDAYVQYELSPYIALGGGKSFWNGLSRFTSPSTSKLMGYDLNFVASPTLDSTDDLIRRLSIYAKGKIGAIDYRFIVAKPLSVQNSSAFNAEPIEGIASFNDKRPHPQFSGYAKYEFWEPESNLSAANVGTYLATKKVLNLGIGFTHQTDALWSLKQGKESYHNMSLFAMDAFMDLPINTDKKTALTTYLSYFNFNFGPNYIRLLGANNPANGVIAEESSFNGRGNAFPISGTGTSTFAQIGFLFESMGKQKNQGQLQPYVAAQYSNFDRFENAMFYYDLGINWYLNGHASKFTLNAENRPIFQDTDTVIRLDERKWMFVLQYQFRID</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEX4</accession>
    <name>A0A5C6ZEX4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">tRNA (Adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">tsaB</name>
        <name evidence="2" type="ORF">ESY86_14590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000905">
        <property type="entry name" value="Gcp-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022496">
        <property type="entry name" value="T6A_TsaB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735">
        <property type="entry name" value="PTHR11735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735:SF11">
        <property type="entry name" value="PTHR11735:SF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00814">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03725">
        <property type="entry name" value="T6A_YeaZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TsaD" evidence="1">
        <location>
            <begin position="36"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="222" mass="24368" checksum="0A20718ED876D4E0" modified="2019-11-13" version="1">MAYILSIETATTNCSVALSNKGETLVLKEDNDPNYSHAESLHSIIDAVLTEAEVSKSQLDAIAVSKGPGSYTGLRIGVSAAKGLCYALELPLIAISTLEALAHQVQAEDGLIIPMLDARRMEVYSAIFKTNYELLREIEAQILDETSFQAELNGSKVYFVGSGVEKTKRIISHENAIFIENKLPSAAQMGAMAYVKYKKSDIVDVAYFEPFYLKDFMVKKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF31</accession>
    <name>A0A5C6ZF31_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_15310</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="218" mass="24350" checksum="716790C2A763FC44" modified="2019-11-13" version="1">MKNLIMFIALSSIVWSCSHDQISDSPSSIDSNESIELKNSRDTLDVLTLEDIDNMFKEEFKDYEEVKISNKLEIDGLKNKSLLKDENLNRSPTLNGPFTVNAVQSLVFSNKKILFSGGQGGLATGIYICDIYKFQSVVSIPLNGAPAADLPTPSGYISASSQTVGINEYTNTTQTSKQYVIATWMINVKYNLNAQFINIDLPNTLQNGFDYTYYYFTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFB3</accession>
    <name>A0A5C6ZFB3_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AsmA_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_12400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032712">
        <property type="entry name" value="AsmA_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13502">
        <property type="entry name" value="AsmA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="AsmA_2" evidence="2">
        <location>
            <begin position="1084"/>
            <end position="1256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1318" mass="148714" checksum="B13F0B8CA16A4F3D" modified="2019-11-13" version="1">MQNPEPRQNKSTSLKWRKRILVALAVLILFPTALFTIGWFNRDTVIDALQDWYGENSSGTLTIGKVNASFISGFPKVGFTLKDIEQTSTDTILDKFSSINIEEAKIVIGAGNLLSGNIKIESIRLKNAVISSEVISKKSLGYHQQLKRDKANKKHKGIIMPEWLHADGVKFVLENITYVTKDSILNKYFNLDIHKIEGSYKGNKNQLLGNLFMDVTVNNLGFNTKKGSYFNGARVTGSPDFTIDLENDSISLPEFLFKVDAQNFDLSANFDFSSSNHYEFKLQNLKTNFNATKGLLPDSLAAKVAKFDIQKPFETKLQLRGKFTYGNNPDLEIHFSTDSNAVNVGQKIHLKNTSFSGNLTNDIYETDSLRDAKRTVKDLKVTFNNLNADLGAIKVDINNSYYKSTPETLNFIKAQINLNGSNEALAKLIEMDNFDFEGGTFQLNAVISGDINTPSEFINKATGHFNLANTRVVLKKNGLQLPLETIDVSLEREHSTLRQLIVNLPNGEDLVLKGSLKNIAGLLSKNPTTPTTSSISLNSKRLNINNIIALSKQFIPKSQKNRDDRKTLHEILNAVYKQFHPSFDINVDALTFNDFTINDLRSHIDLVDSKTILMRSFDFDYYGAFTSLKGSVVLPENNLKDAIYINAEATSRGNISVFEQLFDIQLFRFDAGDYQFHGNVKGNVKEFNEILNNAEGDFTLTNTKLHYPPANMDIDIDSLALFVDNADLHLKKFNLEIGELYPIKLSGKITGFPKFLMDDAQDSAAIFLKINAPFIDSNTWLTTLNSLKYDDKLKTPKGNSGMFRLFKDLNTFNPEIEIEIDSLKYKDLITDQLKAKVYFENDSILKLNNLSLNYKQTTANISGKVKAHIAQLDTLDTNPFDLDVLVSVDGKSEDLNDYLKTKNFIFKSGDFEFKWHYKAQSKNLEIVNPTGSGDLKISNTLVDYTAAGLQIPVDSLHIAIDNDVARLKTLDIDLPGKSSVFFSGAINQFSNFINNDRDEKVHSSNFLIYSPYLDDSDIKAFFANASSRTKKQNADEGALKTFKKALVGINSSFYPTATVKIDTLRHDDLQVTNFGIQLLFDHRGNFEIQDTHLNFYGGSLALNVDVGLQAKNDIPINMEMRADAINLNELVSQLNYFNDDALRNAEKIEGTLNFNIETIGKLNYDGKVDMNSLNGKLHLDLSNFKLYNYKPIVENSVLMKDERFEKLSFRPIVQTFEIRNGEIIIPRTEIQSSAIHFFAEGRFKLNEYMNVWLSLPWKNLKSNDGLTLPEKTTFANAGSKFYLQLVQDKTEEKEKNRDLKVKFRLSNRKLGKMKQAQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFH6</accession>
    <name>A0A5C6ZFH6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_16710</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000023">
        <property type="protein sequence ID" value="TXD87534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046138">
        <property type="entry name" value="DUF6140"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19637">
        <property type="entry name" value="DUF6140"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="69" mass="7885" checksum="222D155888C18377" modified="2019-11-13" version="1">MATFEIKTKEKMNVNGEFVDKGLSVQMSSMFSNPFDEADKIHKAFLRVHGIDLKPEGYLSLGYLEFKLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFJ7</accession>
    <name>A0A5C6ZFJ7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_16160</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023025249" evidence="2">
        <location>
            <begin position="23"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="217"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="244"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="221"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="256"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="279" mass="31389" checksum="F6EFDBE7E211E9E7" modified="2019-11-13" version="1">MNLKPFLFVLGCLLLFSASGFAQDNVHTLLKKNINPLADRLTEELSVSRDSLLLENDLLFSKIRFFNEEQKYDKTFYFKPAVKKGKIALTDLPLGSYSVMFYQIDRIIVFRVDRLSKFNNIIKTVDKIEDPAILADINFRPKAAAFKRADEKSLDPNQSSKFSDMAINASDFDLNTNAQNARPPGLMDTSTKGFGQSGDGDYDLASTGLSSKIIPMDSRFGTGSKGSQNGETFDSNSIYFESGRKGIQPYDLSNQDRDHVQTRDDYRSTHLRPNGKPYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFP6</accession>
    <name>A0A5C6ZFP6_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosome maturation factor RimP</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 6" type="primary">rimP</name>
        <name evidence="6" type="ORF">ESY86_14330</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for maturation of 30S ribosomal subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RimP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01077">
        <property type="entry name" value="RimP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003728">
        <property type="entry name" value="Ribosome_maturation_RimP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028998">
        <property type="entry name" value="RimP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028989">
        <property type="entry name" value="RimP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035956">
        <property type="entry name" value="RimP_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33867">
        <property type="entry name" value="PTHR33867"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02576">
        <property type="entry name" value="DUF150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17384">
        <property type="entry name" value="DUF150_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75420">
        <property type="entry name" value="SSF75420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="DUF150" evidence="4">
        <location>
            <begin position="30"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="DUF150_C" evidence="5">
        <location>
            <begin position="79"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD88061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="154" mass="17244" checksum="652B08DDF29F8FFB" modified="2019-11-13" version="1">MFKDTVKRLLEEGLEQRPDLFLIDFDVLSDNTIKVIIDGDNGVLVEDCMFISRAIENNLDREETDFSLEVLSAGATAPLSNQRQYKKNIGRTLSVQTKDGETIEGTLDEATDDHIILSWKSREPKPVGKGKVTVNKRAEVVYGTISKAQVVIKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFR7</accession>
    <name>A0A5C6ZFR7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_10655</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024187">
        <property type="entry name" value="Sig_transdc_resp-reg_cit/mal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45526">
        <property type="entry name" value="PTHR45526"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="13"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="337" mass="39222" checksum="22991225757A93B0" modified="2019-11-13" version="1">MPQRLPDYSEKLSVLIIEDNQGDFVLIEDYLLEKFKSIEIIHFTNFANSIDYLQNPKTKVSLILMDLHLPCLKGIELINTILAYNFHIPVVILTGYSDIDLAKKSLQIGVYDYLIKDEINPVILHKTIIYALNRSSFINQIEAEKSNYENLFNFSPQPTWLLDSKSLKIRNANDAAQKKYGYSLTQFLEMSFTQLFPIEEEELIKHKLISQEYELNSDHFTHFLSNGEEIKVDIYFREINGRSTHGLIVQSNDVSKTLQHISTIEVQNEKLRKIAWTQSHMVRAPLARILGIINVIEMEKMDADELLFYLKQLRVSGNEMDEIIRKIVNETNHIEKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFT4</accession>
    <name>A0A5C6ZFT4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribose 5-phosphate isomerase B</fullName>
            <ecNumber evidence="4">5.3.1.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpiB</name>
        <name evidence="4" type="ORF">ESY86_12710</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LacAB/RpiB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.6" evidence="4"/>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004751">
        <property type="term" value="F:ribose-5-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004785">
        <property type="entry name" value="RpiB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003500">
        <property type="entry name" value="RpiB_LacA_LacB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036569">
        <property type="entry name" value="RpiB_LacA_LacB_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30345">
        <property type="entry name" value="PTHR30345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02502">
        <property type="entry name" value="LacAB_rpiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005384">
        <property type="entry name" value="RpiB_LacA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89623">
        <property type="entry name" value="SSF89623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01120">
        <property type="entry name" value="rpiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00689">
        <property type="entry name" value="rpiB_lacA_lacB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="D-ribulose 5-phosphate binding" evidence="3">
        <location>
            <begin position="8"/>
            <end position="9"/>
        </location>
    </feature>
    <feature type="region of interest" description="D-ribulose 5-phosphate binding" evidence="3">
        <location>
            <begin position="66"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>D-ribulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>D-ribulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>D-ribulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>D-ribulose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR005384-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR005384-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="144" mass="15714" checksum="F873CF27974E623E" modified="2019-11-13" version="1">MTISIGNDHAGTEYKNAIVKHLKAKGHTINNYGTDSNDSVDYPDFVHPVAKDVAAKKVDFGIIICGSGNGANMTANKHQEVRSALCWTKEITTLARQHNDANILSIPARYTAVQQAIGMVDAFLETAFEGGRHQKRVDKIPAEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFW2</accession>
    <name>A0A5C6ZFW2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Acyl-ACP--UDP-N-acetylglucosamine O-acyltransferase</fullName>
            <ecNumber evidence="7">2.3.1.129</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">lpxA</name>
        <name evidence="7" type="ORF">ESY86_10395</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.129" evidence="7"/>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD89007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008780">
        <property type="term" value="F:acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03351">
        <property type="entry name" value="LbH_UDP-GlcNAc_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029098">
        <property type="entry name" value="Acetyltransf_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037157">
        <property type="entry name" value="Acetyltransf_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010137">
        <property type="entry name" value="Lipid_A_LpxA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43480">
        <property type="entry name" value="PTHR43480"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13720">
        <property type="entry name" value="Acetyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000456">
        <property type="entry name" value="UDP-GlcNAc_acltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01852">
        <property type="entry name" value="lipid_A_lpxA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="1" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Acetyltransf_11" evidence="6">
        <location>
            <begin position="173"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD89007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="262" mass="28759" checksum="6C0E011073B12163" modified="2019-11-13" version="1">MNQPLAYVHPGAKIAKNVVIEPFTTIYSNVTIGEGTWIGSNVTIMEGARIGKNCSIFPGSVISAIPQDLKYNDEDTLTVIGDNVTIRECVTINRGTTDKMKTVIGDNCLIMAYCHIAHDCIVGNNCIFSNSSTLAGHITVGDYVVLAGMTAVHQFCSIGNHAFVTGGSLVRKDVPPYVKAAREPLSYVGINSVGLRRRGFSAEKIREVQNIYRILYQKNYNNTQASDLIEAEMEATPERDEILQFIKNSHRGIMKGYFKSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFY5</accession>
    <name>A0A5C6ZFY5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Leucine--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Leucyl-tRNA synthetase</fullName>
            <shortName evidence="9">LeuRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">leuS</name>
        <name evidence="16" type="ORF">ESY86_13895</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu)</text>
            <dbReference type="Rhea" id="RHEA:11688"/>
            <dbReference type="Rhea" id="RHEA-COMP:9613"/>
            <dbReference type="Rhea" id="RHEA-COMP:9622"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78494"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 10">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.4" evidence="9"/>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004823">
        <property type="term" value="F:leucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006429">
        <property type="term" value="P:leucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.740.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00049_B">
        <property type="entry name" value="Leu_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007569">
        <property type="entry name" value="DUF559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002302">
        <property type="entry name" value="Leu-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025709">
        <property type="entry name" value="Leu_tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015413">
        <property type="entry name" value="Methionyl/Leucyl_tRNA_Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43740">
        <property type="entry name" value="PTHR43740"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04480">
        <property type="entry name" value="DUF559"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13603">
        <property type="entry name" value="tRNA-synt_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09334">
        <property type="entry name" value="tRNA-synt_1g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00985">
        <property type="entry name" value="TRNASYNTHLEU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="SSF50677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1g" evidence="14">
        <location>
            <begin position="38"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="DUF559" evidence="12">
        <location>
            <begin position="322"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-synt_1_2" evidence="15">
        <location>
            <begin position="455"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-synt_1" evidence="11">
        <location>
            <begin position="925"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_1" evidence="13">
        <location>
            <begin position="1015"/>
            <end position="1127"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="9">
        <location>
            <begin position="929"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="932"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF09334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF13603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="TXD88187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1163" mass="132759" checksum="7460919F3C011F59" modified="2019-11-13" version="1">MNYDFNNIEQKWQDYWAKNQTFKASNHSDKPKYYVLDMFPYPSGAGLHVGHPLGYIASDIYARYKRHKGFNVLHPQGYDSFGLPAEQYAIQTGQHPAITTETNIKTYRRQLDQIGFSFDWSREVRTSDPNYYKWTQWIFIELFESWYNLETDKAESVDTLITKFTSEGNADVKAVCDDDIATFSSEEWQQFSSEKQQEILLKYRLTYLAETEVNWCPALGTVLANDEIVNGVSERGGHPVVRKKMTQWSMRISAYAERLLQGLETIDWTESLKESQKNWIGKSVGSEVKFPILSFPQGEAKAGSDNRPGYMTGGNNSHLLLERAKEMRANPTQAEAALWECLRSKKIEAKFRQQHLIGDFIVDFVCLDKGLIIEVDGKIHENQIEEDQKRTERLENDFYKVVRFSNEEVLGNTDAVLKTIIAELEQLESVKDKKHESEQHWSEQVLPLGKDLGWDIAVFTTRPDTIFGVSFMTLAPEHDLVSQIVTEGQKAEVDAYIKSTAKRSERERMADVKSISGAFTGAYAEHPFTKEPIPIWIGDYVLAGYGTGAVMSVPCGDQRDYDFAKHFGIPIPNIFDKVDISEAAYSSKDNVVITNSDFLNGMNYKKAAKRAIFELEKLGQGTGKTNYRLRDAVFSRQRYWGEPFPVYYVNGMPQMIDPKHLPIRLPEVEKYLPTEEGEPPLGRADVWAWCTETNQVVSNDQVNDTTIFSLELNTMPGWAGSSWYFFRYMEPGLSADGESKREETFASEEALSYWENVDLYIGGSEHATGHLLYSRFWVKFLKDREFVSIEEPFKKLINQGMILGTSAFVYGFSVGIKNINPKLEVPLNKIQRYIIPRESYLKGIEGNYDELILSLVEKHLSHYKDAGNVNIEWDLELSPFVPIHVDVTMVNSSNELDIDKFKSWQENFKTLQFVTNENGKYIVGREVEKMSKSKYNVVNPDAICEQYGADSLRLYEMFLGPLEQAKPWNTAGITGVHGFLKKLWKLYHQGENASFSVISSPPLEGLEEVSAEAFKTLHKTIKKVEEDIENFSFNTSVSTFMIAVNELTAQKCNHKDILEPLLILLSPYAPHIAEELWNKFGHAESISTAPFPKFEEQYLVESSKNYPISFNGKTRFTLEIPLSLTKEEVEKIVMAHEKTQAQLDGRVPKKVIVVPGKIVNIVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGF2</accession>
    <name>A0A5C6ZGF2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">FtsX-like permease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_13370</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="301"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="344"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="391"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="439"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="692"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="736"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="778"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="20"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="329"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD88293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="815" mass="91832" checksum="3B909E5EB3078D24" modified="2019-11-13" version="1">MFRNYIKIAWRNISKNKGFSAINVISLAIGLSASFVIGLMVYYDFTFDKFHKDGDLIYRVTTVYNSPEGEDYNYGVSVPLIAEVKQKLTGIQQSTAFFTAEPSKVMNAGFSKAFNNPERVIYADPDFFGFLNYEWLAGNAISAIDAPNKVVLTENRAKKYFPNKSYNEILGETLVYDDSVAVAVTGIVANFKDRTDFTFEEIISLDTGKQSYMQDQITDDNWNSTSSSTQLFVKLNDKNARSKVQRQLDVFAKSNESENAVKYNEHRHFYLQALSELHFGGNYGVFDFTDYNANKTVLTSLIWIAAFLLILGCINFINLNTAQATQRAKEIGIRKTLGSSKKQLIFQFLWETFLLTLFAAFLSILLAAGLIKVFADFLPEGLHFGLFADPFIIGFGMLLLVIIAVLAGFYPAMVLSSFKPVSVLKNRIFITNSHLSLRKGLIVFQFIIAQVFIISTVAVGKQIHFLMEKDMGFKTEAITYIRTPWMDQSLQKREVFIQKLKAIPQIENISLGGSPPASFNTHATEVVYLNGKTEVRTDLELLYGDEAYLNLYDIELLAGRKLRNDTIHEYVINDACRKVLGFESPAEAIGKTLGQGKDAVPIVGVMEDFNQRSLKTQIQPMAFVGDWSRKRYSQFNTIHMQLNQQGSKNWPETIAKAETAWQTVYPESDFKMEFIDQTIAKFYQTESSMTKLLNWATGLSVLISCLGLLGLVIYTTERRVKEIGIRKVLGASLAQLNLLLCKDFIVLVLVAFIVAAPIAYYGLHNWLQDYAYKTRLNWWIFAASGFGIVALALIIMSVKTLSTASKIPVKSLRTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGY9</accession>
    <name>A0A5C6ZGY9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_11555</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1113" mass="130840" checksum="E8A180555E7469FB" modified="2019-11-13" version="1">MHNGFFITHDIYEEWTLDKIVSRKYANYSDIKDFFVDLGNSLPIRRAFRLWLSNQLSDNSQEIEGFIKEAFSDSSIVQFWKDELLIYVLLSDYSESFFKFFENEIIAQEFQILKRILFLLRIACTDISAFKSIDIIKPKGKGWQEVIAFIYEYKADFFDNNMNLVLPLLTDWCNYNKKGETTKYSGLLALSVIQKTETEQNFYIHDKAEENLLKVVYNSANEIKLELKETFDKVLKNKWLNHNDPYHGLCLKILVKPYLAKEVIEVLPLSVIDLCNIFWQKQDKKLDNFGYDRDSIENKYGLISRHRSFDYFPASANQTPVNWLLKTTFWDTLNFIIDFTNRAVVNYQQTNYDKDDFKEITLYIDEQEITQFTSWTLWSLYRGITGPSILQCIHMALEKFLLELSKIVPIEKFKPILIDILRKSKSASLTSIVCSVVLSNPDKFYDIAIILFKTIELYHLDMSRSSSEFQVKSTCSIGYGMNRAKDILYTDERLKACENEHRSSHLERLMLNYQLYGIKGFTEEENTEFIKKLHKILDEHKSNLSKFSKSEEDLYTILLARMDRRNLTAKVKEQVDNKLLIEFEPKELSDELREKSKQANIDFEETFKYSFLRSWSDFLIGGRSQNKNSKHEEYNKDPLLALSETKQLAGELEKGKRGIKMLDYSIPAFVCSKLIIEYGSKLSKKDKNFCKKIISSSLASLFSDDYAYQISDGVEASFHAIPRLIQEFPDEKEDYLSIMLMALFDKSSIGSYKRICDYVIESIHESKLWEENPKEAQAIFLGYIKLIPIYKSIESEKRKGIGFGRGKTKNAILEEFDKRTSDFTFSKLSFDIEDIDLLDIHDLEIVYQLIPSNTKDSIHLEIITKTLPLLVSRLLMDRRDYNREYGNETDIYFVRLHIFKKLTSFILLRETKEIDIYLEPIINYFEATEEAASFLGEFISAEDKLNKYDQFWHVWNSMYPKIITICGNPRNYQIKEVIINYLLAWRWWTDGIEEWHSLKSESLFLYTKAANDMGHIPSVLYSITRVLNSIGSHFKTEGIDWICNIASNNNLLKLEDLESHTLIYLERFMRKFIFINKQKIREEIRLKNKVIPILDFMIERGSIHGYLLRETIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH15</accession>
    <name>A0A5C6ZH15_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD family hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_12565</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="215" mass="23763" checksum="9759AEEB062463CB" modified="2019-11-13" version="1">MSIKKPKYKCIIFDCDGVLVDSEAIGNQVLVDMANGLGANIDLDYALTHFKGGSMNSGIEKISKLISEPMPANFEAQYREQSFENFKKHIQPIEGVVNIIKQLNLPFCVASSGPESKIRLNLEHTGLLPYFEGNIFSCYTIQKWKPDPAIYLWAAKTMGFKPEECAVIEDSLPGVTAAKAGGFPVLGYAAHDFNNELEGNADVVFQDMKDLEHLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH59</accession>
    <name>A0A5C6ZH59_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">IS630 family transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_08870</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038717">
        <property type="entry name" value="Tc1-like_DDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025959">
        <property type="entry name" value="Winged_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13358">
        <property type="entry name" value="DDE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13592">
        <property type="entry name" value="HTH_33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0814">Transposable element</keyword>
    <feature type="domain" description="HTH_33" evidence="4">
        <location>
            <begin position="100"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="DDE_3" evidence="3">
        <location>
            <begin position="172"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="177"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD89481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="344" mass="40675" checksum="10876D88E5D1BB3F" modified="2019-11-13" version="1">MTKTDFRSVSDQERGIIRRDAIKMIKRGDKKKEIALFYGVHVNTVRDWWKLYQKEGNTSLSYQKRGAKSENKKLLNLYQEKEIQEMITDVMPDQLKLDYALWTTRAVRDLIEREFQIVIGRRAVGNYLNAWGFTPQKPKKRAYEQCSKKVQKWLDEEYPAIKEKAKQEKATIHWGDETGVKNSNHHRRSCAPKGRTPVKKHLSKRFSINMVSTVTNQGLVQFMICKENMNSDILIQFLKQLIKYQENKVFLILDNLRVHHSKIVKKWVTEHIEKIELFYLPSYSPERNPDEYLNCDLKYGLSDKPAPKTQDEMKENLKNHMNMLRNDSARVAKYFKHESIKYAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH80</accession>
    <name>A0A5C6ZH80_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type 1 glutamine amidotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_15070</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C56 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006286">
        <property type="entry name" value="C56_PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42733">
        <property type="entry name" value="PTHR42733"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01382">
        <property type="entry name" value="PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51276">
        <property type="entry name" value="PEPTIDASE_C56_PFPI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DJ-1_PfpI" evidence="2">
        <location>
            <begin position="7"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="186" mass="20654" checksum="E2A285D4AE93CC62" modified="2019-11-13" version="1">MKDLNKKTVAILATNGFEESELREPMNALKKAGADVHIISEEKGKIKSWADGNWGPEYNVDKTLSEVDQKDYHALVLPGGVINPDVLRRNKHAVNVTRSFFEHKKPVAAICHGPWMLAEADVLKGRKITSFSSIKTDMINAGANWVDEEVVVDEGLVTSRTPNDLPAFCSKLVEEVYEGKHEEQVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHB7</accession>
    <name>A0A5C6ZHB7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_10070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="167" mass="19648" checksum="EA1219480E264699" modified="2019-11-13" version="1">MEELEHVPLYKKAKDIQNLVDSVVDVIMDSQLEYETEQEGQMIDDSLTYLGENSDLIPQKIALVHGEDIPYNEKMESACFIKNAAIEILTDLDHIELSGYKDIEYFDLLRNEIDDFRILFAEWVTTFDPWDYEIDRWGLFNPPGVKYDDYDPDDDLPFDIDDFFEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHC2</accession>
    <name>A0A5C6ZHC2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07215</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="13"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="270" mass="29873" checksum="50125F2D601CC25B" modified="2019-11-13" version="1">MEQKSPIAIIGCGWLGLPLAKQFVAEGHTIHGSTTSEEKLAVLALEGIRPFLLDVTSEGIAGQLKACLEGCKILVLNIPPRLRKNPEQDYVGEMQQLLPHIENSSVEQLVFIGSTSVYADDENMPVITEASTFSKSETAQKLVTAEGLFQQNNNFNATILRLSGLIGPNRHPATYLSGRNQIQNPEAPVNLIHRDDAIAIIKSIISQKLWNEAFNASFPSHPAKKEFYTKACEQQNLPLPQFDEQCASKGKTIASNKLLQRLKFQFEHQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHH4</accession>
    <name>A0A5C6ZHH4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8 9">Uroporphyrinogen decarboxylase</fullName>
            <shortName evidence="8">UPD</shortName>
            <shortName evidence="8">URO-D</shortName>
            <ecNumber evidence="4 8 9">4.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 12" type="primary">hemE</name>
        <name evidence="12" type="ORF">ESY86_07500</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>4 H(+) + uroporphyrinogen III = 4 CO2 + coproporphyrinogen III</text>
            <dbReference type="Rhea" id="RHEA:19865"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57308"/>
            <dbReference type="ChEBI" id="CHEBI:57309"/>
            <dbReference type="EC" id="4.1.1.37"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 8 9">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; coproporphyrinogen-III from 5-aminolevulinate: step 4/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8 10">Belongs to the uroporphyrinogen decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.37" evidence="4 8 9"/>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89622.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00321"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004853">
        <property type="term" value="F:uroporphyrinogen decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00717">
        <property type="entry name" value="URO-D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00218">
        <property type="entry name" value="URO_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038071">
        <property type="entry name" value="UROD/MetE-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006361">
        <property type="entry name" value="Uroporphyrinogen_deCO2ase_HemE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000257">
        <property type="entry name" value="Uroporphyrinogen_deCOase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01208">
        <property type="entry name" value="URO-D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51726">
        <property type="entry name" value="SSF51726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01464">
        <property type="entry name" value="hemE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00906">
        <property type="entry name" value="UROD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8 9" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="6 8 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 8 9" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Uroporphyrinogen_deCOase" evidence="11">
        <location>
            <begin position="20"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="25"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="318"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="8">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS00906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TXD89622.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="343" mass="38488" checksum="1E225D7F0146EC9D" modified="2019-11-13" version="1">MIKNDLFLRALKGETVERPPVWMMRQAGRYLPEFMEIKAKYDFFTRCQTPELASEITVQPIKRFGMDAAILFCDILVIPQAMNIEVQMKPNFGPYLPNPIRTQKDVDHVIVPDVKEALNYVYQAIKATKEKLNDEIPLIGFAGSPWTILCYCVQGQGSKNFDKAKEFCFTNPIAAHQLLQKITDTTIAYLKEKVKAGCDAVQVFDSWGGMLSPVDYQEFSWQYIQQIINALKDETPVIAFGKGCWFALGEMANSGASALGIDWTCSPRNARYLTGGNITLQGNFDPTRLFSSPSEIKTMVHQMINEFGKDKYIVNLGHGILPNIPVENAGAFIDAVKSYKSPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHJ2</accession>
    <name>A0A5C6ZHJ2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Gliding motility lipoprotein GldH</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">gldH</name>
        <name evidence="1" type="ORF">ESY86_07600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020018">
        <property type="entry name" value="Motility-assoc_lipoprot_GldH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14109">
        <property type="entry name" value="GldH_lipo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03511">
        <property type="entry name" value="GldH_lipo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="166" mass="18986" checksum="0F9E5B51E8D0E5CA" modified="2019-11-13" version="1">MQKSKFFILMFVSSLVFSCDDKRVFDEYKSVSGAWDKDSVVAFTVTAPDTTNAYNLYVNLRNTNDYKYSNLFLIVELNYPNGKAIKDTLNYTMTRPDGSFLGTGFTDVKENKLWYKGYEAPFMFEESGDYTINIQQAMRQNGMVNGIQKLEGITDVGFRVEQALTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHL4</accession>
    <name>A0A5C6ZHL4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Proline dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_12860</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004657">
        <property type="term" value="F:proline dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006562">
        <property type="term" value="P:proline catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029041">
        <property type="entry name" value="FAD-linked_oxidoreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002872">
        <property type="entry name" value="Proline_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015659">
        <property type="entry name" value="Proline_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13914">
        <property type="entry name" value="PTHR13914"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01619">
        <property type="entry name" value="Pro_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51730">
        <property type="entry name" value="SSF51730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pro_dh" evidence="2">
        <location>
            <begin position="78"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="392" mass="45761" checksum="E08F57593482ADA5" modified="2019-11-13" version="1">MEKIFDNTEAALALKSDSELERARFLFELIKRDTLVKIGAAVTKFALKFRLPVEGLIRSTVFDHFCGGITEDDCLPVIDRMFSKNVHAVLDYSVEGKEEEGQFDKAMFKILKTLEYARHNKAIPYIVFKPTGFGRFEIYEKLTAGKKLTQEEQVEWNRIKNRYDRVCGKAFEYDVPILIDGEESWMQDAADELAESMMFKYNKETAIVFNTLQLYRHDRLDYLKELHQQATEGRFKIGMKLVRGAYMEKERERAIRLGYQDPICKDKATTDALFNEVLIYMIKNLENMALFVGTHNEESTYLVLQIMQRCKIAENDKRIWFGQLFGMSDHISYNLANFGYNVAKYLPYGPVRDVMPFLFRRAEENTSVAGQTSRELYLIKNEMKRRKLVKSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHX8</accession>
    <name>A0A5C6ZHX8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_08275</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="81" mass="9393" checksum="D229F178C2C39F24" modified="2019-11-13" version="1">MKTTTHELSCSIFGHNLEPVYTTSEKSHHCRKFICTSCKTKVNMDANGEVQELPYKNEKISNALRQLFLLKRKSSERQFSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI50</accession>
    <name>A0A5C6ZI50_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_08295</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="146" mass="16487" checksum="7D49D7A40F98C2E5" modified="2019-11-13" version="1">MKKTLLIMLMILTIISCKDEAKSEAEKPSEANEQMSENAKTELQNDGLITVQGTFVYYDDAAVLQTPSGMIGVVVNEKMQDLNKKVQAYKKESTDMVPVTIRGRLFKKPENEIGWENRIEIKEILKVSPPKAGDNEVIRLENKESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI75</accession>
    <name>A0A5C6ZI75_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Big_5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_08470</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032812">
        <property type="entry name" value="SbsA_Ig"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13205">
        <property type="entry name" value="Big_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022996228" description="Big_5 domain-containing protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="domain" description="Big_5" evidence="2">
        <location>
            <begin position="34"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="535" mass="61242" checksum="938B9ACB402919C9" modified="2019-11-13" version="1">MRKIVIQLFVLLLMAIISINCASRGTPDGGPKDIDAPKIVNSSPENYSTNFKEKEIRIYFDEYVKVKDLQKQLIVSPPMDPEPTVTPLGSASEYIQITINDTLDDNTTYAFNFGRSIVDNNEENPYDYYRYVFSTGNYIDSLYVSGTILDAENRMPDSFVSVMLYEADSTYTDSLVFKQKPKYITNTLDSLTIFSIDNIKAGQYKLIALKEETPNNTYQQKTDKIGFTEGFITVPTDSFYTIKLFKETLDFNANRPRQVAGQKIAFGFEGDYESMEIEILGDSLKDLEQRITKDPKADSLFYWYKPKIEMDSALFVIRNKVYRDTLTHKFRDLEKDSLVITPSVSSVLNFTEAYGIRGSIPFVKFDEQQISILDKDSLNVPFTTSFSEIDNTYNLSFDKQEADKYSITILPNAFEDFFGNVNDTLNFRASTKKFSDYGNLRLNIQGNVSYPMIVQIVNAKAEVYASSYLTEGSKVDFRNINPGKYFIRVVLDANENGKFDTGNFLKNLQPEKIIYFDYTYEARANFDEVVELSLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI83</accession>
    <name>A0A5C6ZI83_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_12745</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="183" mass="20892" checksum="97C1A6B95286BE15" modified="2019-11-13" version="1">MNILYLDMKIICILIVSIMALNCKPTKSIDTQNKTHDQVKDCPEDGNCTFEVLTNSAFEIKKDEYGLSYGKLVVSDKTLLRFEYIPNTPENTADGQYNELIYIEIDPDTEMLDLKDEDLKKANVTFGRVCFCPGQNGYYPVTKGQLKLSKLKDNSFELSLNFRAKDLPQVITQINKSFKLEQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIB7</accession>
    <name>A0A5C6ZIB7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">FAD-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_07030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039650">
        <property type="entry name" value="HdrA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43498">
        <property type="entry name" value="PTHR43498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="558" mass="62426" checksum="8A85D19C747977AC" modified="2019-11-13" version="1">MKTNYTIATIILSITISLLAFNTTIEEKQASADLVIYGGTSAGISAAIQTARLGKSVILIEPTNRLGGLTTGGLGQTDIGNKQVIGGISREFYQNIKKYYEVDANWDWQKRSEYKDGGQTQTNKNEDAMWTFEPSAALQVYTDMMKDLDIEIVYNQRLNRSTGVVKSDNAITAITMESGNTYTGKIFIDATYEGDLLAAAGVSYTVGRESNAQYGESLNGVQANVTSQMLNGGLSSNARHHNFVKGVDPYRVSGDVSSGLIPGINPTIAKDGTGDKHIQAYCFRMCLTDHPENRIPFEKPKDYDESDYELLFRNYEAGYNRVPWINSQMPNRKTDSNNRDGFSTDFIGQNYDYPEASYAERERIVQRHRIRQQGLMWTLANHPRIPEKIREEVSRWGTSKDEFERADGWQQQLYIREARRMISDFVMTQKHCESIEVVPDGIGMAAYGMDSHHTQRYVNSEGHVSNEGNVEAYVQGPYPISYRSIVPKKEECSNLLAPICLSATHIAFGSIRMEPVFMVLGQSASVIACMAIEKDKAVQDIPYAELKTQLLELGQIVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIE0</accession>
    <name>A0A5C6ZIE0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08860</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="171"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="292" mass="34275" checksum="53A7D7E602910D1E" modified="2019-11-13" version="1">MENILACPVLAIPEDISYTTPKKIVFPTNYKISFKRRELKYLIDIAQLHNSSIQILHIKESRKLNEAQQGNKAFLETLFKDVDHSFHEMEGMSVHTGINAFIDLRKCDMVAFVNPNHSFFRSLFSTLLVEELGYHSKVPVLVLKDRNLKPKKMQNKPSVLDREIEKLHWHIQRWKADLQFTEHEINFMEQLLNADIYEQNIPDMFERIQQYLQQLKNHKIRTEKLKQLVGNHENLLGTVMKSDIDTIISDFDFKHANVESEVEESKNDFQHFKSEIFNFIGGTLKKNAAHLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIG1</accession>
    <name>A0A5C6ZIG1_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">30S ribosomal protein S15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 7" type="primary">rpsO</name>
        <name evidence="7" type="ORF">ESY86_09980</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="3 6">One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the universal ribosomal protein uS15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00353">
        <property type="entry name" value="Ribosomal_S15p_S13e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01343_B">
        <property type="entry name" value="Ribosomal_S15_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000589">
        <property type="entry name" value="Ribosomal_S15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005290">
        <property type="entry name" value="Ribosomal_S15_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009068">
        <property type="entry name" value="S15_NS1_RNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23321">
        <property type="entry name" value="PTHR23321"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00312">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01387">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47060">
        <property type="entry name" value="SSF47060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00952">
        <property type="entry name" value="S15_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00362">
        <property type="entry name" value="RIBOSOMAL_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 6" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD89091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="89" mass="10493" checksum="65ADB41C5ED7CBD3" modified="2019-11-13" version="1">MYLDQQEKENIFKKHGKDVKDTGSAEGQIALFTYRINHLTGHLKTNRKDYNTERSLVKLVGKRRSLLDYLTKKDVLRYRAIVKELGLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIH4</accession>
    <name>A0A5C6ZIH4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">INTRADIOL_DIOXYGENAS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_10790</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the intradiol ring-cleavage dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016702">
        <property type="term" value="F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006725">
        <property type="term" value="P:cellular aromatic compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000627">
        <property type="entry name" value="Intradiol_dOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015889">
        <property type="entry name" value="Intradiol_dOase_core"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00775">
        <property type="entry name" value="Dioxygenase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49482">
        <property type="entry name" value="SSF49482"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023098380" description="INTRADIOL_DIOXYGENAS domain-containing protein" evidence="4">
        <location>
            <begin position="23"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="INTRADIOL_DIOXYGENAS" evidence="5">
        <location>
            <begin position="60"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD88970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="208" mass="23711" checksum="DB54A23D136AF969" modified="2019-11-13" version="1">MKSILKYAALLLIFVNLQLVVAQELNDSPNQLPSNYMERHPIYDFGEKQLSATDSVPGYKSHEQPLKITGTVFRADGQTPAKDVIVFINQTNDKGVYTVEQENDKDYILHRAWVKTDENGKYTFYTFVPGTNFGSNEIKRIHTYIKQPGSPEYEIDGFLFDNDPYLSRFCRKRLKKAGSNAILNPIKTDDILVANRDIVLLETLQASN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIR7</accession>
    <name>A0A5C6ZIR7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07895</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="170"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="240"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="326"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="352"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="394" mass="45275" checksum="7C096FA5AE9CCACF" modified="2019-11-13" version="1">MIKKRISVEAFSDGFGKIAILLILLGFYLSFLVEGYTGNTSFRNIMMLCSFVFFFIKIALYPRLKIRSDFFAYILCGLIVAGISCWFWYSLAEINVYFTLVTLSLVIISGFEFFKKGLKWLILIILIIALYEYITKTYLFIVYRNTEWGLLPMDPKFFGGYAKIIRAKGLFEGPLALAQFAIGCALIFRKDLKILILTFLLAILANGRLGIIICASVLIFHFIEKYSLLKFLFSAKGLKFLLLGFVSLILAFNYFVTEKSIKRFKDIFDTTGDSGNSARLDYWAQAVDVYWNYDIIHKIFGDSGLYRHITGNSAENGWLMLLLNNGLLGFLYYFIPIVLIFVMSITKKTGHYLFVLLIIFAMFIQTFHLGASANLLYWVIIYTFYLELNQTNNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIY6</accession>
    <name>A0A5C6ZIY6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08255</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="19"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="257" mass="28726" checksum="7E2A6F0113728791" modified="2019-11-13" version="1">MILNYKNIEVHYKDEGKGKVLLLLHGFLENSTMWDSLKPELLKTRRLISVDLLGHGQTGCLGYVHPMGMMAETVAAVLKTLNVIRFSVIGHSMGGYVALALAEQQPNAIEGLCLMNSTFEADDEARKQIRKRSIELAQGNYEALVRMSYVNLFSSESAKKYLNEIEAGLNQALKTSKQGYVAAQEGMCLRSDKLEVLKNLKAKKWMLMGTKDAVIKADPLKNRIGQTDIVLKELGCGHMMHLESITELTYIIKHVIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJE3</accession>
    <name>A0A5C6ZJE3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07875</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="329"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="368"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="393"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="422" mass="48813" checksum="14039DFC10D9C20C" modified="2019-11-13" version="1">MIYLKNHALFFGSLGFGILIWILSYVCLPFYVNEPFHAETIFFVISSYGMLILGFSVLKPRLNSKELMVGHVHKILNILIGIIIISYLFRWIDLFYLRDLSFTNEPKYNRALNEMNSANSNLLLILLSVLKSLYFFPYVISIKTKQHRQRITTILAYLCLFLPLLEAVLKGTRKPLFEIFFIILLTTLVYNRKIITKLRIAITAVIVILLMSISMLVVFQRENLSHAFDTVFYEKLLESRYNEILEPKPSVISFFEDKQTSQVTKFYAMAAMQIGQYIAHGVFEFNHIIKFKALPITYGGYSFSPVTRFFNKIGILNNTKIENPSPREYVYLSSFGAMYIDFRWFTLMFMFLLGCLQKFVTFKSRENVFYAPILIYFSIINVFLPILNYIGGSGIYAILSAAVLLLILKLLGKALNEKSIST</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJI1</accession>
    <name>A0A5C6ZJI1_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">His_kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_09630</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010559">
        <property type="entry name" value="Sig_transdc_His_kin_internal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06580">
        <property type="entry name" value="His_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="His_kinase" evidence="2">
        <location>
            <begin position="147"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="335" mass="39893" checksum="6D720FD659A4F2E7" modified="2019-11-13" version="1">MKLSNKSIRSIKITFNVMFIAIITFELVRETFFSIPEDWLFFLTSDAVENFVFALIAYGLYYYVLKLKDLWKKIGLVSLFIFLLIGLAWLKDFRIHDRIEFEQSFEYFTSFLGQSLLFYLGIYFINRLEYLNRYKKLEKELYRAKEQLLRNQLHPHFLFNAFNSLYSLSLKNHPETSDYILKLSSMMRYLTDETHIKKVPLVKEIDFIKKYIDIEKMRFGKDSSIQLTNVGNINDEELIAPFLLITLVENAFKHGFYTNSKDAFVTINVNIENKELLFTVENSLFKKQHFQESNRKGKGLENLKQRLQLLYPKNSSLKFTNTEETYTAHLKIRLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJJ1</accession>
    <name>A0A5C6ZJJ1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_03180</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM86 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012506">
        <property type="entry name" value="YhhN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07947">
        <property type="entry name" value="YhhN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="33"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="87"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="202"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD90384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="233" mass="27091" checksum="7C78F225C5CDCC43" modified="2019-11-13" version="1">MRTLFVNILSFSLLYFTVVLLDLLAMYIVDLEMIRFITKPLLIVLLIVFYASNDKESTSGKFVFLIIALGFFLLANVATLFRTEPMIIMSASIFFILGKLFYIFRFANRRDFDIVKFLPFVAFYLLYMFVVLSFILDHLGSYLIPVLLFLFVSLMAMQFAFLRKDEVSEASYQLVLFGIFTMLFGDTIRVLDAFYFHWTYGSLSAMLLYAMSQYLIVMGLVKEKIDLKPLISE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJQ3</accession>
    <name>A0A5C6ZJQ3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_09640</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="27"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="59" mass="6818" checksum="9F64187E7686BF85" modified="2019-11-13" version="1">MNWTRQQKEGNSDGSMGSKSKIQIMKSYKINKKEAEQKSRKQKKENALDIISKSISKPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJZ3</accession>
    <name>A0A5C6ZJZ3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">M48 family metallopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_04415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002725">
        <property type="entry name" value="YgjP-like_metallopeptidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01863">
        <property type="entry name" value="DUF45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF45" evidence="1">
        <location>
            <begin position="21"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="233" mass="27549" checksum="5AC6393F629116D5" modified="2019-11-13" version="1">MHKIQYGSQEIFYELKRSNRKTLGIEVHPDSSVHIIAPTESSFQDIEQKVEKRAKWIVKQQAYFEQFLPRTPERNYVSGETHYYLGKSYLLKVTLGIENQVKLKGGKLEVVCKNEIKQEQVKKLLAHWYYVHAEKKFSSIAIDAYSKFKEYDFNMPEIEIRRMAKRWGSCNTIDKVILNPEIIKASSKCIEYVLIHEMCHLVVTNHNKEFYNTLGSIMPTWKKWKDRLEQKLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK31</accession>
    <name>A0A5C6ZK31_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_08955</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="145" mass="16429" checksum="5FBF14A64B246694" modified="2019-11-13" version="1">MKNKILIIISLLICCTCFSQKKITWHDLAQVEFSEKFFPAFGEYFLYPKFLPSVKDLEGKQVVITGYFLNIDPQGKLFILSKGPMSSCFFCGVGGPETAIELQFISKQHFKTDDIVTITGTLKLNADDVEHFNYILTDCKGQIIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK72</accession>
    <name>A0A5C6ZK72_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HipA domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_04345</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012893">
        <property type="entry name" value="HipA-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07804">
        <property type="entry name" value="HipA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HipA_C" evidence="2">
        <location>
            <begin position="53"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="312" mass="35650" checksum="A2E75387313765A1" modified="2019-11-13" version="1">MSKCLYCYKEVASGEDFHRECSLAFFGVENPPKIEYSLKEMSELALEVVERSVSVPGVQPKISMSLIEDNKKDKRLTVVGALGGNYIFKPPSEDYAEMPANEHLTMKMAELFGIEVVTHSLIKLASGELSYITKRIDRNEDGSKIHMIDMFQVVEAFDKYRGSMERIGKAIHEYADNTLLDLLRFYELTVFSFLIGNNDMHLKNFSMIKTSYGWALSPAYDLLNVAIVNPLDKEELALTIAGKKKKITKKILFDFGVGLGLSKKQIEGVFKRFKELQEVAIDLIKISFLSESMQRNYIELIENRYHLFNKTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKQ5</accession>
    <name>A0A5C6ZKQ5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MerC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015097">
        <property type="term" value="F:mercury ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004891">
        <property type="entry name" value="Mercury-R_MerC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03203">
        <property type="entry name" value="MerC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="117" mass="13253" checksum="B4085E441E3904CD" modified="2019-11-13" version="1">MTQTKKIYWADKLGAISAFLCIVHCLSVPAFLTMGIGFLENPVIAYLFIFVAFISIYNATKGKIFKGISIFLWVAFAGFVTSLLLEERAEIFEYLMFFFSASIVIGHIYNIRNCLKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKS7</accession>
    <name>A0A5C6ZKS7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_04405</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007421">
        <property type="entry name" value="Schlafen_AlbA_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038461">
        <property type="entry name" value="Schlafen_AlbA_2_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04326">
        <property type="entry name" value="AlbA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AlbA_2" evidence="1">
        <location>
            <begin position="26"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="421" mass="48510" checksum="A18B8E1034E78C50" modified="2019-11-13" version="1">MQSPLDNDIIVELMKTKANGRLYKRESTALEFKSDFDWDIRESRIKYLKSIASFANRLGGYMIFGVSDSPRLISGITKSFMEIDDYQISQFINLYLSPAPDFEREEFLINGKKIGVMFIHPIDRKPVVCIKSYGNIMSDSSIYYRYNSLSCIINSGDLIHLLEEAKQKENDKWMKLFTSASTVGVHNAGIFDIKSGKISTQKGNSYVLDENLLKRLKVLDKYSQQEDGAEAVRIIGEIDKTGTVINRPFAIHDDDIIIGFLGDKDINAPIEYLEAMCYQSSGFMPIYYYINKTDFNIEDILKKLKKVKTRSQAKKKLIARLEDDSNILNQRKSLIMENSTSVRTKRLRYHNQLINGEEIIYKNTGEVKRLLEAICNLQHGTFNFAYVKNVLIDVYNNYFNTDLSSFIRKTVCYLDLLENKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKY8</accession>
    <name>A0A5C6ZKY8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Trehalose-6-phosphate synthase</fullName>
            <ecNumber evidence="7">2.4.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Alpha,alpha-trehalose-phosphate synthase [UDP-forming]</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Osmoregulatory trehalose synthesis protein A</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">UDP-glucose-glucosephosphate glucosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">ESY86_03750</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-glucose 6-phosphate + UDP-alpha-D-glucose = alpha,alpha-trehalose 6-phosphate + H(+) + UDP</text>
            <dbReference type="Rhea" id="RHEA:18889"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:58429"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:61548"/>
            <dbReference type="EC" id="2.4.1.15"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Glycan biosynthesis; trehalose biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the glycosyltransferase 20 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the C-terminal section; belongs to the trehalose phosphatase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the N-terminal section; belongs to the glycosyltransferase 20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.15" evidence="7"/>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00299"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003825">
        <property type="term" value="F:alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004805">
        <property type="term" value="F:trehalose-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005992">
        <property type="term" value="P:trehalose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03788">
        <property type="entry name" value="GT20_TPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001830">
        <property type="entry name" value="Glyco_trans_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006379">
        <property type="entry name" value="HAD-SF_hydro_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012766">
        <property type="entry name" value="Trehalose_OtsA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003337">
        <property type="entry name" value="Trehalose_PPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788">
        <property type="entry name" value="PTHR10788"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00982">
        <property type="entry name" value="Glyco_transf_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02358">
        <property type="entry name" value="Trehalose_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01484">
        <property type="entry name" value="HAD-SF-IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00685">
        <property type="entry name" value="T6PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02400">
        <property type="entry name" value="trehalose_OtsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00018539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TXD90489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="732" mass="85427" checksum="DE559C658AFE2FD5" modified="2019-11-13" version="1">MNKTIIVSNRLPLQIKIENDQLEVTPSVGGLATGLKSVHNDGKSLWIGWSGLTEEELSEARSKEVKKLVTAAKCDSVSLTQDDLENFYYGFSNRTLWPLFHYFMEYTEFDNDYWESYKAVNQKFADKVLEHLEDGDTVWVHDYQLLLLPKLIKEKMPNTTIGFFLHIPYPSYEIFRTFPWREELLHGMLGADLIGFHTYDYERHFLSSVKRILRLEVNFNEVTYHDRIVKVDSFPMGIDYDKFHDSASKHKTDKKSELQQRLDDHIQSGSDAKMILSIDRMDYTKGIPNRIRAFEYFLNKYPEYKEKVRLIMLAVPSRSNVPQYQKLKRDTDELVGRINGQFSTVSWTPIWYFYRSMPFENLIDLYTSSHVAMITPVRDGMNLVAKEYVATRTEQDGVLILSEMAGASKEMNESMLINPNNFEHIADTIKYALEMPLEEQKSRMKILQKRLKRYTVEKWAEEFMKSLHATKHLGAVIVANRLEKEIENNMLTEFNSAERRLFLLDYDGTLVAFKDNPIEASPDEQLYQLLDTLSANNKNDVVLISGRDRETFTHWFANKEYTLITDHGVWLKEEGKDWEALERLKNGWMENIKPILETFVDRTPGTFIEEKKYSLAWHYRKADPELAQIRTIEIDTVLTSLISNNDLSVLKGNKVIEIKSSSVNKGRASSRLLANNDYDFIFCIGDDWTDEYMFQELPKSAYTVKVGFKKTSAKYYVKDTDEVREVLHKFMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL33</accession>
    <name>A0A5C6ZL33_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022977299" evidence="1">
        <location>
            <begin position="20"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="344" mass="39972" checksum="F114D25B2A9A06F0" modified="2019-11-13" version="1">MTKNILRLLVVILTFNSCASILNSSTTEVKLYAPIDTQVVYNNDTTVVSNAYVKITAQRSKDSLRVRVVKDAIVNDFAFKRKISGLFYLNLPYTYGLGFLVDLTNPKRFTYRKTINIKMDSMSNSFFISEEKLVPFKRNDFFLYTSPLMAIDAFSQPMLSLGGEYFFKDDVSISAEAGLKYTERLRSNSAVDLVEDRSHSFRMELKWYNIASLTGNGRINEYVGLEARFLRHQFTDDINYTISDGDIFYARNEDFIVQKKVNVFNIKYGLNFPIGKRLYFDLYTGFGIRYKTIKNPNRYYDPAKHRNYDDEDGFLFWPNTNNLEEEGKQKLFNFSLGFKFGVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL74</accession>
    <name>A0A5C6ZL74_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_04280</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045621">
        <property type="entry name" value="BPD_transp_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19300">
        <property type="entry name" value="BPD_transp_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="9"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="136"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="172"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="279"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="325"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="132"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD90592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="358" mass="40021" checksum="928C4D21B690D797" modified="2019-11-13" version="1">MLNYLLNKIFYALLTLFGVVTVIFFLFNVLPGDPAQMMLGQNEDSDQIAAVKAKYGFDKPLSTQYFYYLNDLSPISFHSTKTSDYTYLAEGKYSAITLFTIGEHTTVIKFPYLRESFTKQGKKVSEVIAETLPNTAILAVSAICIAIILGVILGIVSALFKDQWLDKTIQVFSTLGMSVPSFFSAILFAWFFGFVLHKYTNLEMTGSLYELDDFGEKMQLQLKNLILPAVVLGIRPLAVVIQLMRNSLLEVFNQDYIRTARAKGLSEIQIIRRHAVKNALNPVVTAISGWFASMLAGAVFVEYIFGWNGLGKEIVNALNTLDLPVIMGAVLVIALLFIIINIFVDVIYGWLDPKVKLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLA2</accession>
    <name>A0A5C6ZLA2_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="14 15">Dihydroxy-acid dehydratase</fullName>
            <shortName evidence="15">DAD</shortName>
            <ecNumber evidence="14 15">4.2.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15 16" type="primary">ilvD</name>
        <name evidence="16" type="ORF">ESY86_02290</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>(2R)-2,3-dihydroxy-3-methylbutanoate = 3-methyl-2-oxobutanoate + H2O</text>
            <dbReference type="Rhea" id="RHEA:24809"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:49072"/>
            <dbReference type="EC" id="4.2.1.9"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:24810"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>(2R,3R)-2,3-dihydroxy-3-methylpentanoate = (S)-3-methyl-2-oxopentanoate + H2O</text>
            <dbReference type="Rhea" id="RHEA:27694"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:35146"/>
            <dbReference type="ChEBI" id="CHEBI:49258"/>
            <dbReference type="EC" id="4.2.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="15">Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 15">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="13 15">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 3/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="12 15">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the IlvD/Edd family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.9" evidence="14 15"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00057"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00061"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004160">
        <property type="term" value="F:dihydroxy-acid dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00012">
        <property type="entry name" value="IlvD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042096">
        <property type="entry name" value="Dihydro-acid_dehy_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004404">
        <property type="entry name" value="DihydroxyA_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000581">
        <property type="entry name" value="DiOHA_6PGluconate_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020558">
        <property type="entry name" value="DiOHA_6PGluconate_deHydtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037237">
        <property type="entry name" value="IlvD/EDD_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00920">
        <property type="entry name" value="ILVD_EDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143975">
        <property type="entry name" value="SSF143975"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00110">
        <property type="entry name" value="ilvD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00886">
        <property type="entry name" value="ILVD_EDD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00887">
        <property type="entry name" value="ILVD_EDD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 15" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3 15" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 15" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="7 15" id="KW-0408">Iron</keyword>
    <keyword evidence="8 15" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9 15 16" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="15">
        <location>
            <position position="473"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" description="via carbamate group" evidence="15">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="447"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-carboxylysine" evidence="15">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00029437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00029490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="TXD90809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="559" mass="59765" checksum="11A40887F7E57050" modified="2019-11-13" version="1">MSQLNKYSKTVTQDPTQPAAQAMLHAIGLTKEDFYKPMVGIASTGYEGNPCNMHLNDLAKLVKQGTKNEDIIGLIFNTIGVSDGISMGTPGMRYSLPSRDIIADSMETVVQAMSYDGLITVVGCDKNMPGALMAMIRLDRPSILVYGGTIDSGCHNGKKLDVVSAFEAWGSKVAGTMDETEYQHIVEKACPGAGACGGMYTANTMASAIEALGMTLPFNSSNPALSDAKQQESVKAGEALRLLLEKDIKPSDIITRKSLENAVRLVTILGGSTNAVLHFLAIARAAQIDFTLKDFQEISDNTPFLADLKPSGKYLMEDVHRVGGIPAVLKYLLKNGLIHGDCLTVTGKTLAENLLDVDDLAEGQDVIKSIEEPIKISGHLRMLYGNLATEGSVAKITGKEGLHFRGKAKVFEGEYAANDGIRDGKVEKGDVVVIRYEGPKGGPGMPEMLKPTAAIMGAGLGKDVALITDGRFSGGTHGFVVGHITPEAQEGGNLALVKDGDMIAIDAETNTITMEVSEEELSKRRQHWKAPALKFKRGVLYKYAKTVSSASKGCVTDEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLC7</accession>
    <name>A0A5C6ZLC7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_08680</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="284"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="312"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="344"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="42"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="376" mass="42808" checksum="A8DE81B4573E7515" modified="2019-11-13" version="1">MLLIIILIITLLYVALIGSFVIGFDRVEIFKLTDKTPKTGFTIVIPFRNEAQHLPILLKSLLKLRYTKQLFEIILVDDDSSDASVAIIEKQLPRFKNVSITILKNTRKTDAPKKDAITEAIINAKHDWIVTTDADCQVPIFWLNCLDAFIQQRDSNCIVLPVAYVAQNSLLSRFQILDMLSLQASTIGGFGINKPFMCNGANLAYRKTAYHEVEGFEGNSHIASGDDVFLLEKMLKKAAHKVNYLRSSKAIVLTKSQQSLRHLISQRVRWAAKTSNYKNKFGKITGIIVLLMNALLLVFPFLLLLGIISLKLFIYILIIKFCLDFLLLFKSARFFEQESALSSYMWSCFIYPFFSVYVAILSVFNGYNWKGRAYLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLH0</accession>
    <name>A0A5C6ZLH0_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">tRNA dimethylallyltransferase</fullName>
            <ecNumber evidence="5">2.5.1.75</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Dimethylallyl diphosphate:tRNA dimethylallyltransferase</fullName>
            <shortName evidence="5">DMAPP:tRNA dimethylallyltransferase</shortName>
            <shortName evidence="5">DMATase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Isopentenyl-diphosphate:tRNA isopentenyltransferase</fullName>
            <shortName evidence="5">IPP transferase</shortName>
            <shortName evidence="5">IPPT</shortName>
            <shortName evidence="5">IPTase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">miaA</name>
        <name evidence="9" type="ORF">ESY86_00955</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 5 7">Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5 6">
            <text>adenosine(37) in tRNA + dimethylallyl diphosphate = diphosphate + N(6)-dimethylallyladenosine(37) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:26482"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10375"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74415"/>
            <dbReference type="EC" id="2.5.1.75"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 5 8">Belongs to the IPP transferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.75" evidence="5"/>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052381">
        <property type="term" value="F:tRNA dimethylallyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00185">
        <property type="entry name" value="IPP_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039657">
        <property type="entry name" value="Dimethylallyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018022">
        <property type="entry name" value="IPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11088">
        <property type="entry name" value="PTHR11088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00174">
        <property type="entry name" value="miaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 6" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="12"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with substrate tRNA" evidence="5">
        <location>
            <begin position="35"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with substrate tRNA" evidence="5">
        <location>
            <begin position="159"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="10"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Interaction with substrate tRNA" evidence="5">
        <location>
            <position position="101"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with substrate tRNA" evidence="5">
        <location>
            <position position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD91188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="301" mass="33980" checksum="DD1A7A3C25AFACC0" modified="2019-11-13" version="1">MSNYLISIVGPTAIGKTRLSIALARHFDTEIISADSRQFFKEMQIGTAAPTADELEAAPHHFIHHKSITDSYNVGAFEKEAMASLEQLFKNHDTVIMVGGSGLYVDAVTKGLDEFPKVDPEIRNSLNAKLKAEGLEALQLQLKNADPKSYATMAVDNPQRVIRALEVCISSGTPYSDFLTSENKQRSFKTISIGLTAERVKIYERIEARVDLMMAAGLLDEVETLLPQKHLNALQTVGYKELFNYLEGEWDLEFAISEIKKNSRRFAKRQLTWFKRDASTLWFDYETPQHQIIDAIESEIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLJ7</accession>
    <name>A0A5C6ZLJ7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Amidohydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_03985</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022661523" evidence="2">
        <location>
            <begin position="20"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydro-rel" evidence="3">
        <location>
            <begin position="289"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydro-rel" evidence="3">
        <location>
            <begin position="858"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="528"/>
            <end position="565"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD90535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1005" mass="111245" checksum="4C38D640239EC3FE" modified="2019-11-13" version="1">MSKIKLALVLCLCSFAIHAQEYFPKNDGVKTKNTNFTALTNAKIYVTPTQILENATLLIKDGKVVSSGKSVAIPKNTNVIDLEGKTIYPSFIDMYSSFGIEKPKQQGGGGRNPQYDPTRTGYYWNDHIMPEQKAISSFKYDDKAAKELMAAGFGVVNTHVEDGIVRGTGALVALNNEVGNGSRILDDNSAQYLSFEKSEASKQAYPTSTMGAMALLRQMYYDADWYAKGNIETKDLSLEALNKQKNLVQIFDAGSRANALRADKVGDLFQIQYVILGGGDEYERIADVKAMNATLILPVNFRDAYDVENSFLSASLSLSDMRAWSQEPANAKVLAENGISFAFTTNALKSPKTFLENVRKAIAYGLPKETALAALTTIPANVLGKSAEIGSLQNGAYANFLITSGDIFDEKSTLFENWVQGERTVLDDMMVKDIKGDYEFSLAGEAYKMSLKGEPSKLKVEITSEGKKRGSKINYSDDWLYLTMTTQDSTKQQFIRLTANLTKSDDLNGKAIFPDGNEMTFYAKKVEASETASAENPEKTDEDAEEDSEEKDKSDGPKTTAPLTYPNVAFGFDELPKQETLLFKNATVWTNETDGTLENTDVLIKNGKIAKIGKNLSDASAKTIDATGKHLTAGIIDEHSHIATSSVNEAGQNSTAEVTIEDVLDAEDIDIYRNLAGGVTSIQVLHGSANPIGGRSAIIKLKWGESPENLIYKESPQFIKFALGENVKQSNWGDEARNRFPQSRMGVEQLYIDYFTRAQEYAALKKSGKPYRKDIEMDVLAEILNSNRFITCHSYVQSEINMLMKVADQFDFNINTFTHILEGYKVADKMAAHGVGGSTFSDWWAYKYEVNDAIPYNAAIMHNAGVTVAINSDDGEMARRLNQEAAKSVKYGGISELEAWKFVTLNPAKLLHIDDRVGSLKVGKDADVVLWSDHPMSIYAKAEKTIIEGVTYFDLQRDQQMRTKLKAEKSDLINQMLIAKNKGLKTQPIKKDEKVQMHCDYIDQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLN3</accession>
    <name>A0A5C6ZLN3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Efflux RND transporter permease subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_05235</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004763">
        <property type="entry name" value="CzcA/CusA/SilA/NccA/HelA/CnrA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00914">
        <property type="entry name" value="2A0601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="336"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="362"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="445"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="475"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="536"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="865"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="890"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="918"/>
            <end position="939"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="960"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="995"/>
            <end position="1022"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="7">
        <location>
            <begin position="317"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD90151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1026" mass="112445" checksum="3864316476F0B3CE" modified="2019-11-13" version="1">MLNKILSISLHNRLLILLGAVALSVLGVYYARTMNVDVFPDLTAPTVTILTEAHGMESEEVEKLVTYQLETALNGSPNVRRIRSSSAAGISIVWIEFEWGTDIYRARQIVSERIPMVRENLPEGIGAPTMAPISSIMGEIMLLGVTSDSLSPMELRTLSDWTIRPRIKAIGGIANVVVIGGDYKQYQVFANPEKMKHYNVRLTELVEHVKEANTNAPGGVINQYGNQYIIKGSGRAYALEDLEEAVLKQVNGQSIKIKDVATVQIGAADKIGDGSLNAKPAVILTISKQPDVNTLELTDRLDEAIVDLQKTLLKGVDIKSQIFRQSDFIDASISNLNQTLLEGAFFVMIILLIFLMNWRTTLISLLAIPISLLVSIIILKWLGYTINTMSLGGMAIAIGALVDDAIIDVENVYKRLRENIRKPKEERESTLTVVRDASVEIRSSIIIATLIIIVSFIPLFFLSGMEGRLLQPLGIAFVTSVLTSLIVAVTVTPILCSYLLDNEKLLKKQSEGTKVERWLQKHYGNLLERATRIPKTIIGVTVIAFIISMLVLTQLGRSFLPEFNEGSMVISVVGPPGMSLEESNKTGNLIETILLDLPEVEVVTRRQGRAELDEHAQGVNASEIDVPFVLEDKTKEAFFEEVRNKLSIAPGVNITLGQPIAHRIDHMLSGTRANIAIKIFGPDLQRLYEVGKSVEQNIKDIDGLADVAVDQQIEVPQIRIQPKRQILSAYGMTVGNLMEQVDIAFAGEEAGEIYEGQKYFDLVVRYEKPFRDDIENIGNALISLPNGGQTTLGELATVASVSSPSKISREDVQRKIVVAANVQGRDLRGAVEEIKEVVANNVNMPEGYRIQYGGQFESEAKASQLLSITAIVAIAIIFLLLYYEFKDVKLAFVVLINLPLALIGGILIVYFTSGIISIAATIGFISLFGIATRNGILLVSRYEDLRKEGIKGFQLIKTGALDRLNPILMTACTTGLALIPLALKGGEPGSEIQSPMAVVILGGLLSATVLNLLVIPCVYMLVVKRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLS5</accession>
    <name>A0A5C6ZLS5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Four helix bundle protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_01920</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012657">
        <property type="entry name" value="23S_rRNA-intervening_sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036583">
        <property type="entry name" value="23S_rRNA_IVS_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05635">
        <property type="entry name" value="23S_rRNA_IVP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF035652">
        <property type="entry name" value="CHP02436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158446">
        <property type="entry name" value="SSF158446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02436">
        <property type="entry name" value="TIGR02436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="124" mass="13994" checksum="E0D90290A1884AFA" modified="2019-11-13" version="1">MANYKYDLEERLIQFAVEVILICGKIDGNFASQHLAKQLIRSATASALNYGEAQGAESSRDFLHKMKICLKELRESLVNLKIQKGANLIKDIERLDKLLSENNELIAIFVSSIRTAQSKNNIQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLY2</accession>
    <name>A0A5C6ZLY2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phenylacetate--CoA ligase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_07850</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="440" mass="50302" checksum="8A64B5652C9A81F3" modified="2019-11-13" version="1">MNLFDLTLKLNGFPLKAAKEALVAIHQKNEIDFAASLKAKKKAILAHHLKYNAYYRDFVSDANVSTWEQLPVMTKRDLQVPLKQRLSEGYSTASVYVNKTSGSSGDPFVFAKDKFCHALTWAVIQDRFSWYGLDFNHSKQARFYGIPLDKKGYYKERIKDYFGNRFRFSVFDLSDAAFEKCLHQFRTTAFDYINGYTSAIVQFAKYLQRRDIILKDLCPSLNVCVVTSEMLFEQDKILLESQLGLPIVNEYGASELDLIAFQNPNDQWQVNSESLFVEILDPNNQVLPYGEEGRIVISSLYNKAHPFIRYDIGDLGSLSKDSSTKKPILQKLVGRSNDIVLLPSGKQAAGLTFYYITKSIIENDGKVKEFVIEQHQIDQFKVAYVGTEILSEAQQQNIIKAMTRYLEPGLTVIFERQEQLQRSKSGKLKQFTSLLNQDKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM21</accession>
    <name>A0A5C6ZM21_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Septum formation inhibitor Maf</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_03465</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="321" mass="36708" checksum="357A4FEF7CE8D400" modified="2019-11-13" version="1">MLKSLFYQSENFGLTCLIVFFLVTSCKNSSENKNVNPLIPDSEATKMLQTLPKQTKFESSQAFVKYWQSGEAEISSYQLQQARYGELREGKAVLIFVTEPFLPQKQVKADLSAVSNVQVLKLNATKNFNTGIYPYSIMQSTFYPLSNTSHALKVSCSIQEWCGQVYSQLNNREQFEITSHSYFEMEADAQFNLEKTILENELWTQLRLDPSSLPVGDLKIIPSLEFISLKHMPTKAYDAVAQLTTGNYTVSYKVLQRQLSISFNPEFPYQILSWEETYPDGFGEDPTVLTSKATLLKSIKSDYWNKNDNTAIRFRDTLQLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM28</accession>
    <name>A0A5C6ZM28_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Zinc-dependent metalloprotease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_01775</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04276">
        <property type="entry name" value="ZnMc_MMP_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033413">
        <property type="entry name" value="DUF5117"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033428">
        <property type="entry name" value="DUF5118"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032534">
        <property type="entry name" value="EcxA_zinc-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034032">
        <property type="entry name" value="Zn_MMP-like_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16313">
        <property type="entry name" value="DUF4953"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17148">
        <property type="entry name" value="DUF5117"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17162">
        <property type="entry name" value="DUF5118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5118" evidence="4">
        <location>
            <begin position="32"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5117" evidence="3">
        <location>
            <begin position="89"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4953" evidence="2">
        <location>
            <begin position="411"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="13"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="812" mass="91811" checksum="F6B11A8E31FCB2AF" modified="2019-11-13" version="1">MVSCNTTKKAAASAEAEKSKSDSEKKAGKDDPKPYDKVITKEAISDSGLFTVHKLDEKYFYEIPDSLFDREMLMVTRIAKTASGLGFGGGKQNEQVLRWQKMDKKVVLRVVSYNVVASDSLPISEAVANSNFEPVLYTFPIEAFSKDSTSTVIDATPLFEKDVQSLGLPSFRRKPYKVTKLESDKSFIEAIKSYPRNIEARSVKTYAAGEPPSNSSTGTISIEINNSMILLPDSPMKRRYFDERVGWFTSSQTDYGLEAQRSKELEYLDRWRLEVKDEDIEKFNRGELVVPKKQIVYYIDRATPYKWREYIKQGIEDWQVAFEAAGFKEAIIAKDPPSAEEDPEWSPEDVRYSVVRYLASPIPNANGPHVSDPRTGEILESDINWYHNVMTLLRGWFFVQTAAINTEAQSPEFRDDVMGRLIRFVSSHEVGHTLGLPHNMGSSVAYPVESLRDAEFTKKNGTAPSIMDYARFNYVAQPGDEGVALMPDIGTYDKYAISWGYRPIFDKTAEEEKPILNEWIMKHAGDPMYRFGHQQAGDVVDPSSQTEDLGDDAMLASSYGIKNLKRIVPNLITWTTEDGEDYDDLEYMYGQVVAQFNRYMGHVSNNIGGVYEIYKTADQEGAVYTPVAKEKQAEAMQFIQDNLFTTPEWLLDETIFNRIEFSGSVERVRGLQERTLNNILDLGKMQRLTEAETFNGEDAYALTDMMSDLRNGVWSELQSGKTIDTYRRNLQRAYIDRMAFLMTAKDKSGRSNSTYVKATAVNASQSDIRPIVRAELKSLSRSLKAARGADTMSKIHIADALERVDMILNPNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM30</accession>
    <name>A0A5C6ZM30_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Thiol peroxidase</fullName>
            <shortName evidence="2">Tpx</shortName>
            <ecNumber evidence="2">1.11.1.24</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Peroxiredoxin tpx</fullName>
            <shortName evidence="2">Prx</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Thioredoxin peroxidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Thioredoxin-dependent peroxiredoxin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">tpx</name>
        <name evidence="5" type="ORF">ESY86_00725</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>[thioredoxin]-dithiol + a hydroperoxide = [thioredoxin]-disulfide + an alcohol + H2O</text>
            <dbReference type="Rhea" id="RHEA:62620"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:35924"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.11.1.24"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="2">The active site is a conserved redox-active cysteine residue, the peroxidatic cysteine (C(P)), which makes the nucleophilic attack on the peroxide substrate. The peroxide oxidizes the C(P)-SH to cysteine sulfenic acid (C(P)-SOH), which then reacts with another cysteine residue, the resolving cysteine (C(R)), to form a disulfide bridge. The disulfide is subsequently reduced by an appropriate electron donor to complete the catalytic cycle. In this atypical 2-Cys peroxiredoxin, C(R) is present in the same subunit to form an intramolecular disulfide. The disulfide is subsequently reduced by thioredoxin.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peroxiredoxin family. Tpx subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.24" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008379">
        <property type="term" value="F:thioredoxin peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03014">
        <property type="entry name" value="PRX_Atyp2cys"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00269">
        <property type="entry name" value="Tpx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013740">
        <property type="entry name" value="Redoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002065">
        <property type="entry name" value="TPX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018219">
        <property type="entry name" value="Tpx_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08534">
        <property type="entry name" value="Redoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01265">
        <property type="entry name" value="TPX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 5" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="2" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="18"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate" evidence="2">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="2">
        <location>
            <begin position="60"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD91146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="166" mass="18053" checksum="1630163C84B2AEA6" modified="2019-11-13" version="1">MAQVTLHGDKIHTQGTLPKKGSTAPNFKLTATDLSTKTLKDYSGHNVILNIFPSVDTGTCAQSVRSFNKKAGDVENTKVLCISKDLPFAFSRFCAAEGLDHVESLSDFKDGNFGKHYEVTFTDGPMEGLLSRAVVVIDPDGKVIYTQQVPEIADEPDYESALQALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM35</accession>
    <name>A0A5C6ZM35_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TolC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_02785</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="421" mass="47909" checksum="2852C29137CFBCF2" modified="2019-11-13" version="1">MQHQVSSVQVSASSFQFLITLTLALVAQNFASAQSLESYIEEATASNPEIQAFELRYNIAEEKVNEANWIPNTEVSAGYFLSETETRVGAQRARIGFKQMLPWFGTISARENYASSMAEAEFVEITIAKRKLGLSVAETYYKLYEIRAKQIVLVENIQLLETYERLALTSVEVGKASAVDVLRLQIRQNELVQDKKVLEQQAFGIQAAFNSLLNRDHDVPIETVTELALPEEETAFSYDGLSLNPELLKYDKLYESVAQSELLNQRESAPMIGFGLDYLPVSKRTDMDLFENGKDIVMPMVSVTIPIFNNRYKSISKQNELRQQEIETQKDQRLNVLESALAKAISQRNQARIKFEIQTKNLKQAQDAEEILIKNYETGTIDFNDVLDIQELQVKFQMNLIEAAQMYYVQSALINYLTKQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMB4</accession>
    <name>A0A5C6ZMB4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sodium:solute symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_04795</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="119"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="152"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="182"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="233"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="272"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="317"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="372"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="397"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="429"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="454"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD90073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="480" mass="54003" checksum="C3FC40EB7B7486B9" modified="2019-11-13" version="1">MSSTLIILLIASYFAVLILISLLTGRKSTNDTFFKANRQSPWFVVAFGMIGASLSGVTFISVPGWVEASKFSYMQVVLGYIIGYFVIGTVLLPLYYRLNLTSIYTYLEGRFGAYSYKTGASFFLISRVVGASFRLYLVANVLQIILFDDLGVSFWQTVTITVMLIWLYTFKSGIKTIVWTDTLQTLFMLVAVGVAIYFVSDELGLSGGGILGYVMDSDLSQVFFFDDYKSSDYFWKQFISGAFIAIVMTGLDQDMMQKNLTCRSLKDAQKNMFWFTIVLTITNFVFLSLGLLLTVYAQQNGIDAQKDDLFPLLAKNHFGIGVFVFFLLGLIAAAYSSADSALTALTTSFSIDIMEIEKNNSEAKQVRLRKRIHIAFSFVLIFVIVAFKYVIKDESVIAKLFVFAGYTYGPLLGLYAFGLFTKWNVKDKLVPFIAIASPILSYIISFYSQKWLGFEFGFFILILNGLVTFLGLILVRRQHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMX9</accession>
    <name>A0A5C6ZMX9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha/beta fold hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_02185</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008220">
        <property type="entry name" value="HAT_MetX-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32268">
        <property type="entry name" value="PTHR32268"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000443">
        <property type="entry name" value="Homoser_Ac_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="3">
        <location>
            <begin position="37"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="127"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="270"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000443-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD90790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="340" mass="38580" checksum="1C340F0E7EE4769E" modified="2019-11-13" version="1">MKDLKYIELKDFTTNSGFKSNIHLSYHSFGKVLNTAPIVLVNHALTGNSTVCGNEGWWTDLIGKDKCIDTQDYTVLAFDIPGNGYDGNPSHLIENYKAFTAVDIARIFSEAIDQLQIKTLFAVIGGSVGGGIAWELAAIRPKLIEHLIPIATDWKATDWVIANCHIQDSILNNSNNPLFDARLHAMTLYRTPESFTQKFKRTEREKGFFNVESWLSHHGTVLNKRFQVSAYKLMNQILRTIDITQGDNARFLEIASKIESNIHLVTINSDLFFKSEENWNTYVELKSVKDNVSISEIKSLHGHDAFLIEFNQLAKFLKPIFKKKQQTNQFEVHVEALKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN26</accession>
    <name>A0A5C6ZN26_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_01285</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="119" mass="12821" checksum="FA7C8545B8709DCD" modified="2019-11-13" version="1">MSVFNSISETTDKATDIGEKYYNASLQYFKLKLFKRVASVLSIVAKLAIVGILALLTILFLAVSAAIAIGQELDNLALGYLIVGGILLLLAIIVVSLGSVIDGKILKNLSDKFWDDDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNE9</accession>
    <name>A0A5C6ZNE9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Rhodopsin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_02475</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the archaeal/bacterial/fungal opsin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001425">
        <property type="entry name" value="Arc/bac/fun_rhodopsins"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01036">
        <property type="entry name" value="Bac_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00251">
        <property type="entry name" value="BACTRLOPSIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01021">
        <property type="entry name" value="Bac_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="110"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="142"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="165"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="206"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="245"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD90844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="280" mass="31771" checksum="D9FAA76EF947BF61" modified="2019-11-13" version="1">MTQELGNANFENFIGATEGFSEIAYQFTSHILTLGYAVMLAGLLYFILTIKNVAKKYQMSNILSAVVMVSAFLLLYAQAENWTTSFTFDGSRGRYFLNPEGDLFNNGYRYLNWLIDVPMLLFQILFVVSLTKSKFSSIRNQFWFSGAMMIITGYIGQFYEVSNLTSFFVWGAISTVFFFHILWVMKKVINEGKEGLSADAQKILSNIWVLFLVSWFLYPGAYLMPYLTGLDGFLYSEDGVMARQLVYTVADVCSKVIYGVLLSNLALKLSNSKEMVEVTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNK8</accession>
    <name>A0A5C6ZNK8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphoesterase</fullName>
            <ecNumber evidence="2">3.1.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_04235</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the metallophosphoesterase superfamily. YfcE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.-" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110165">
        <property type="term" value="C:cellular anatomical entity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024654">
        <property type="entry name" value="Calcineurin-like_PHP_lpxH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000979">
        <property type="entry name" value="Phosphodiesterase_MJ0936/Vps29"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11124">
        <property type="entry name" value="PTHR11124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12850">
        <property type="entry name" value="Metallophos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00040">
        <property type="entry name" value="yfcE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos_2" evidence="3">
        <location>
            <begin position="3"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD90583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="164" mass="18657" checksum="353E61DE2820C7C9" modified="2019-11-13" version="1">MTKILLLSDTHSYIDDAILKYVRQADEVWHAGDIGNLEVTDAIKKLKPLRAVYGNIDGKEARAEFPENNRFMCEGVDVLMTHIGGYPPKYNPRTRELIQANPPKLFICGHSHILKVMPDKRLNILHMNPGAVGKHGFHQVRTMLRFTIEGAKIENLEVVEFPTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNN7</accession>
    <name>A0A5C6ZNN7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">T9SS type A sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_06070</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003410">
        <property type="entry name" value="HYR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02494">
        <property type="entry name" value="HYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50825">
        <property type="entry name" value="HYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022955515" evidence="2">
        <location>
            <begin position="21"/>
            <end position="1168"/>
        </location>
    </feature>
    <feature type="domain" description="HYR" evidence="3">
        <location>
            <begin position="996"/>
            <end position="1077"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD90300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1168" mass="120817" checksum="7673443B4C2003D3" modified="2019-11-13" version="1">MKHVLLIFTLFCASYMTVNAQTNTWTGAGANTNWNTVANWSLNAMPTAANDVVIPTGFTVNLNVAGDTKSIVVQGNSTFNMSNTLSILNASSVAANATCAWTLGSLTGGGTLTNNGTFNLSSGNTKSIVGVTTFNNTGNFNILDGGDLNITDGIFNNLASGIIDLRGNEGNISYTGSASRILNNAGLIKSTATGGNVRIQTVLNNNGGAITVSNGNLIFDFLDKNLNGGVLNVSVGSVLRLTSTTNLTGTLTGALNGDLEWSGNVSSAGTSTFNFSGSSGVRWTAGNLTGGGTLVNKNLIFLSSGNTKSIIGVTTLNNEGDFNIPDGGDFNITDGIFNNQLTGTIDMQWAEGNISYTGSASRILNNAGLIKSTATGGNVRIQTVLNNNGGTITVSNGNLIFDTLDKNLNGGVLNVSVGSVLRLTSTTNLTGTLTGALNGDLEWSGNVSSAGTSTFNFSGSSGVRWTAGNLTGGGTLVKKNLIFLSSGNTKSIIGATTLNNEGDFNITDGGDFNITDGIFNNQLTGTIDMQWAEGNISYTGSASRILNNAGLIKSTATGGNVRIQTVLNNNGGTITVSNGNLIFDFLDKNLNGGMYNVSVGSSLQWNSNTVISGTLTGNLTGEIDWLNDITIPNATTGTFNFTGNSGVKWSSGNLTGGGTLVNKSLIFLRTANTKSIIGATTLNNEGDFNITDGGDFNITDGIFNNQSAGTIDMQGAEGNISYTGSASRILNNFGMLKRTTTAGNARIHTFLNNSGSIDAQAGTLVFSEFLAFTNDEEGVVKGVSTVTIANTANYTNNGTFSPGGSPGTLTFNGVFKSSTTSVLDVELNGLTSGTQYDVLAITGTNAIFDGDVNVTLGFEPVVGNTFTVATTTGTITTKSLATPFTSDYLGKRYTFNVTYPNDNVVRLTISNILDIEAPNVITQNATVQLNASGNGSITAAQINNGSSDNCSLVADLTYTLSKSTFNCSNLGANTVTLTVTDEAGNSANQTATVTVVDAINPTVTCGGDSTIDSNGNYALPNYVTNSTASASDNCSATVVQAPVAGTSLADGTYTISFVATDSSGNTANCSFSLTVVDTTLGIDDFELSESSIQLYPNPVGNVLTIKNVNNLELDNAQITDVTGKVITTFDLKNMGLTKEISLEDLSSGMYFLKINGLNSSVTKRVIKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNS5</accession>
    <name>A0A5C6ZNS5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_00490</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="855" mass="99324" checksum="17534B0858E0BD20" modified="2019-11-13" version="1">MTQTITDYPIFEADQVLSQKHLNQLVSYLEEQDRLSRVYLQGMGIVCGLEISKPNATTIHVNCGTAITSLGFLIPFEENDYTQYKESTISEDFLAADVSKHGYLGTIYQWADEYAALSPCVELLSRDSEDDERQPLTNSILQNKIVMLLLESPLIDEKNCVTIDCADKGKRLELNVRVLLVDSELLSKLQFNLSNCAFNYLSRLKLPRFNVPKTNLITGNHIFNAFKAVINQSKKTLSESIQTVHQHFEPFHGNLENFSQLQNALTIINSMHQKFDDTLYIQYVWDWLNDMAATYNEISHYHACQLSICCPKQNDFPFHVLLGSAEKETASINHNNNLYNYRTHFINTGINSTEEKEKHEVLKGLLQKLIYQLGSFWVMAAPNQQQVVRITPSNIGCKLHSERAIPYYYTNIPTLNEYWSPILTQKALHRNILSYHADTYNTSNLQVNQPLLYDLECYDFFRIEGHIGQDYAEAITEIVALQETYRLPFKVVALNAVEYANQEIDISNQSGIWDDMELDYDLAKEKIYNITEYVITWIKTNKKKIQEHYPVMNDQSITNLESILKESRNLLVDDLKDFIPNYEGFYEVFENLNELFIMHRLCISLINKDDMHPVMEDLIDHFDEINNLFLEDPFTIINEEVQRRWGNSVKELFLTNFLQKHQGIDHEAGVPKGGTFILIYADTNIFKKPKPSEKNNIFIDRIVSYKKLFDFNEQQLEQVEKNNVVKKRARLKGKGKPEPENDKWLEEKRQLGKKFKAAMSQDNSKLPFATRAFIENQMNDFFDRNLGRIQVTDNTENKIPQRVIIADFYLPYICCGNGDSINIIINQEVDNEPIVADFDHRDFDENDFFTNRDNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZP83</accession>
    <name>A0A5C6ZP83_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_00700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018170">
        <property type="entry name" value="Aldo/ket_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43827">
        <property type="entry name" value="PTHR43827"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000097">
        <property type="entry name" value="AKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00062">
        <property type="entry name" value="ALDOKETO_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00063">
        <property type="entry name" value="ALDOKETO_REDUCTASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="4">
        <location>
            <begin position="17"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="49"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Lowers pKa of active site Tyr" evidence="3">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000097-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD91141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="282" mass="32382" checksum="815A4850E9D4F03D" modified="2019-11-13" version="1">MSKHIILNDGNKIPMLGFGTYKSTDQEGTEAVRFALSNDYQLIDTAAIYKNEAAVGKGIKASGINRDELFVTTKLWRTHLGYESAKEQFAESLERLQLDYIDLYLIHWPANAKNYENWQQANADAWKAMEKLQAEGKIKSIGVSNFWQEHLEALFQTAKVRPSINQIEFHPGYWQKDLVAYCKTQNIAVESWSPLARGEVFENDLLKRIAATHQKSVAQVCLRWILQHNVIVIPKSTTNKRILENREVFDFELSAEEMDRIDHMPKMGFSGESPNMWPDSVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPF7</accession>
    <name>A0A5C6ZPF7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Biotin carboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_01615</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="3">
        <location>
            <begin position="228"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="33"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD91307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="572" mass="65019" checksum="0FB2584FCA5CA9E3" modified="2019-11-13" version="1">MDSKKPNTPKSKGTTDKKSKSPLKTGTDRTKVPIRGTADKEKKQTASNSKTAKAKPKPAAKKSKATAKPAKSSNKTTGNKKAVTSSTPGIKALKGVSDIRRSFHKNEEPLYFISATNFNLLGADEWIKGFKFITYIECFDGLHPNVFSPKQEIPHDDFDGIEDINNYLLQHPEVQDYLKTRSVDGRPGKAMFLMFNEETERLAEKLGLEIMFPSAEMRTFLDNKVNTNRIAERAGVPCVPYVLSKVNNYKHLTKVSKKLGTQLVIQTPFGDSGHTTFFISNEKEYKKYAEEIEAEDEVKIMKRIRCIGSAIEACVTRHGTIVAPLMTELVGFKELTPYEGGWCGNEIYPNAFTPELRQKAIDNTQLFGNQLREEGYKGYFELDFLIDQDNGEIYLGELNPRVTGASSITNHAVFALADAPLFVFHILEWMDIEYELDIEAINKRWSDQDNLDGWSQLIVKHTEDTIEYVTDAPKSGIWRMYDTGHIQYDRMDTHRRAVENENEAFFMRISKKGDYLYEGADMGILVTRGRMMTDDFELNNRAKHWIKAIRSQYKSEMVEDKKKPKLSGTLTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZQ42</accession>
    <name>A0A5C6ZQ42_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">2-isopropylmalate synthase</fullName>
            <ecNumber evidence="3">2.3.3.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_02200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the alpha-IPM synthase/homocitrate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.13" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003852">
        <property type="term" value="F:2-isopropylmalate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901566">
        <property type="term" value="P:organonitrogen compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002034">
        <property type="entry name" value="AIPM/Hcit_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00815">
        <property type="entry name" value="AIPM_HOMOCIT_SYNTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00816">
        <property type="entry name" value="AIPM_HOMOCIT_SYNTH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="2">
        <location>
            <begin position="6"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="391" mass="42857" checksum="CB7E65D09B9965A9" modified="2019-11-13" version="1">MSDNNIQIFDTTLRDGEQVPGCKLNTKQKLVIAEKLDFLGVNVIEAGFPVSSPGDFKSVSEISKLIKNATVCGLTRAVENDIKVAAEALKYAKTPRIHTGIGTSDSHIKYKFNSTQDKILERAYEAVKYAKTFVEDVEFYAEDAGRTDNAFLARICEAAIKAGATVLNIPDTTGYCLPNEYGAKMKYLMENVKGIEKAILSCHCHNDLGLATANSIEGVINGARQIECTINGIGERAGNTALEEVVMILKQHPYLNLDTSINTRHLYALSQLVSESMGIYTQPNKAIVGANAFAHSSGIHQDGMIKNKNTYEIIDPKDVGVTDSAIVLTARSGRAALAYRAKNVGYDLTKLQLDDVYANFLHFADEKKEIDDNDIHHIIESSKVYQQIISA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZQ73</accession>
    <name>A0A5C6ZQ73_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_00290</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_3" evidence="3">
        <location>
            <begin position="47"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase" evidence="2">
        <location>
            <begin position="600"/>
            <end position="950"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD91073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="972" mass="109785" checksum="B847132544AB31E2" modified="2019-11-13" version="1">MRYIMPFIFCCVVTMPIFGQTADHPLAAKDLFLQKKWVDSIYNGMSLEEKVGQLFMARAFSNQSKAEENRVAKLINENHIGGLIFSSGGPVRQANLNNLYQAISKTPLLIGMDAEWGLSMRLDSTYAFPWNMTLGAIRDLELVEKTGYQIGEHTKRIGVHFNFAPAVDINTNPNNPIIGNRSFGEDRENVTQKGDAFMRGMQAAGVLANAKHFPGHGDTDVDSHKALPTIDFNERRIDSIELYPYKELIKNGLSSVMVAHLSVPSLEPRPGLPSSLSKAIVTGILKERLGFKGLIFTDALEMKGVSNFGKDGEVDLAAFQAGNDVLLISEDVPVGIAKIVEAYKNKDITEERLALSVKKILMAKFKVGLENYQPIGTANLVEDLNRLKDDLLYSQLMEGAITVIKNKGEILPLRNLATKKIAYVELGDDSGSPFFDELKKYTKVHMVQDISLNAIMTKLQNYNTVVIGFHKNNENPWKDYKFTEKELTWIYEIARTNTVILDVFARPYALNDLLSFENIEGVVMSYQNSKISQEKSAQLLFGAIPALGVLPVSINDDFKVGQSVYYNAIQSLSYGLPEQVGMSSEKLNRLDSIAQYAIDGKMTPGIQLLVARKGKVVYNKNFGKHRYTGDEKVKFDDMYDVASLTKILATLPLLMELEEKNVVSLDTKLSKMLPEYASSNKRNITIKQMLSHYARLKPWIPFYVATLDPENKKPDPKYYRRVPSLKYNIKIAEEMYLRKDYPDTMQKIIKETDLLSSLRYRYSDLPYYILKEYIENYYDKPMDELVQDHFYQSLGANYTTYNPSPMFSNTNLVPTEIDDYFRFQEVQGFVHDMGAAMENGVGGHAGIFSNANDVAKIMQMYLQKGFYGGKRYLKPETIDKFNTCYFCSQDVRRGIGFDKPQLSESGPTCGCVSMTSFGHSGFTGTYAWADPEEEIVYIFLANRTYPNAGVNTLLKEDIRTDIQRLIYEAIIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZQP8</accession>
    <name>A0A5C6ZQP8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_01760</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="253"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="283"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD90953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="350" mass="40596" checksum="5A0338A6A0991C2E" modified="2019-11-13" version="1">MCFCCFGNLLYAQHCFNGYIDNERWHNEVYLSVIDDYRTLKGINDEQIISKAISNAQGYFEFHGNQLEGSNKIYKLHVDNCSDGDHEANHFEGYCKDSKDILFIAKSGDTINFPLGFEDQVFCNVKSTNAKTSAFIKIDSLKEDMRFDYAEYRSKANRNLNNNKWFKALHEYGKSLKEPLAELYIYAYLSDRSNNLHGYYLEDLKVNTYYEHLLERLKTAYPNSSYTKQYEAELNADKYIISAISSEKPAFKWMYLVLGLLLLSLITNAYFLYSAKKIKPKSKTDVKEQLTPQELNVLDLLLKEYSNKAIADTLFVSVSTIKTHINNIYKKLNVNSRDKVKSLFNSELTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6Z9C8</accession>
    <name>A0A5C6Z9C8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GRAM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_20820</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000136">
        <property type="protein sequence ID" value="TXD85737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004182">
        <property type="entry name" value="GRAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02893">
        <property type="entry name" value="GRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="domain" description="GRAM" evidence="2">
        <location>
            <begin position="74"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD85737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="182" mass="20846" checksum="62C33AC44C3BA250" modified="2019-11-13" version="1" fragment="single">MIKLNWKFRIVSAILTGLLFVGIMCLMDYLLGGEFQSMNSYLFQGIFFGIFMGIGFPYVTQKFGTKFTSKIGKNIKPELTQDENVEIEGPANLFRGMEGVGGKLFLTNKKVVFKSHEINIQKGQTDILYENITEIIKRKTAKIIDNGIRIKTNGGNEFDFVVNEREKWIEKLNEKITHYNTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZA71</accession>
    <name>A0A5C6ZA71_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">IS110 family transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_20660</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000100">
        <property type="protein sequence ID" value="TXD86018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003346">
        <property type="entry name" value="Transposase_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002525">
        <property type="entry name" value="Transposase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01548">
        <property type="entry name" value="DEDD_Tnp_IS110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02371">
        <property type="entry name" value="Transposase_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEDD_Tnp_IS110" evidence="2">
        <location>
            <begin position="9"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="158"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="330" mass="37209" checksum="32BECD24265B7722" modified="2019-11-13" version="1">MNKDIKYFGIDISHLVFDVTDSDGNYYQFKNNGSGFKKFVKLLSLDSHCVMEATGYYHYQLAYYLLESGIKLSVENPLAVKRFIQMKLSKIKTDKSDSKLICDYAQQVDLKLWKGNSKDEMECLQIVRALAIYTKQSTMLKNKLHGESVLGEPSKGVVRSLNRSLKQLEKEVKILEDKLIGLVNESHQDLLTRLRSIPGIGPKTAMMLVVLTGGFDRFTSAAELCSYAGLTPVIRQSGTSVNGRARISKIGNQKLRNLLFMCSFNACKVNKACRDLYERIVAKGKSKKLALIAVCNKLLKQAFAIAKSGLIYDDNYRSTCFDPYKTRVIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZA78</accession>
    <name>A0A5C6ZA78_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_20450</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000076">
        <property type="protein sequence ID" value="TXD86279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="155" mass="18001" checksum="CBAEABD86C277F92" modified="2019-11-13" version="1">MKTHIITGIISLIVLMTFSSWNSKQNLKTNEIAENRTENINSKMEENYRTLRLVVSYDFGENLKTISEKATPEIIKSTMESINWNEFHIVQLEDENENALHVSGSLYEDGLASGYVTENDHILIVNPPKSVKEMTEILIEFLKGEEIWRNKYEYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAF9</accession>
    <name>A0A5C6ZAF9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA-directed DNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_18850</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="1"/>
    <dbReference type="EMBL" id="VORO01000034">
        <property type="protein sequence ID" value="TXD86926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011708">
        <property type="entry name" value="DNA_pol3_alpha_NTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040982">
        <property type="entry name" value="DNA_pol3_finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029460">
        <property type="entry name" value="DNAPol_HHH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004013">
        <property type="entry name" value="PHP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003141">
        <property type="entry name" value="Pol/His_phosphatase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004805">
        <property type="entry name" value="PolC_alpha"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32294">
        <property type="entry name" value="PTHR32294"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07733">
        <property type="entry name" value="DNA_pol3_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17657">
        <property type="entry name" value="DNA_pol3_finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14579">
        <property type="entry name" value="HHH_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02811">
        <property type="entry name" value="PHP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00481">
        <property type="entry name" value="POLIIIAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="SSF89550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00594">
        <property type="entry name" value="polc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0235">DNA replication</keyword>
    <keyword evidence="5" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="POLIIIAc" evidence="7">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD86926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1016" mass="117434" checksum="838DCBCB0B0582E2" modified="2019-11-13" version="1">MYLNCHSYYSLRYGSIAPKQLLAIASANGVNTLALTDINNTSACLDFVRLSQDFKIKPILGVDFRNGAQQQFILIAKNNFGFLNINSYLSQFLHDQDLKIPERPEQPIEDCYVIYPYQSGKEYDLKSNEFLGIKPKDLNALKFSRWNKLQHKLVILKTVSFQNKKGFNTHRLLRAIDNNTLLSKLSKAEEGDPKNCMMPYQELCDTYQEFPKLIANTRELMADCSIDFDFSQKIPNNQKCYTNNEALDFRLLRKLTYKGLHYRYKKPGTRIFERIEKELKVIEQKNFVSYFLINWKILKYARSKNYFYVGRGSGANSIVAYLLRITDVDPVELDLYFERFINLFRQNPPDFDLDFSWKDRDDITEFIFKTFKHTALIAVYNTFKFRASVRELGKVFGLPKAEMDLLTRGKYNIDQLDKLSQLVIKYSTYIEGFPNYLGIHAGGILISEKPIHQYGATFMPPKGFATTQFDMVVAEDIGLYKFDILSQRGLGKIKEATEIVAYNHPEKPPIDIHDIKRFKKDERIKHLLRNAKAIGCFYVESPAMRMLLKKLQVDNYLGLVAASSVIRPGVAKSGMMREYILRYRFPEKRKEAPEVLLKIMPETYGVMVYQEDVIKVAHHFGGLDLGEADMLRRGMSGKFRSREEFMKVKQQFFDNCKADGKPDAMVADIWRQIESFAGYAFAKGHSASYAVESYQSLFLKAYFPLEYMTATINNFGGFYSTELYVHEARMHEGIIEAPCINTSFTQAIIKGKTIYLGFMFLQAFESKLMKQIVAERHKNGLFENLDDFIDRVPISIEQLSILIKINAFRFTGINKRELLWEARLKISKTPMEEHIMTLFKTEKITYKTPKLSSTDLENAFDEMELLGFPLCNPFDLLETEFSNERRASQLLEFQQKTITIEGYLVATKHTKTSNGKVMHFGTFLDYDGDFVDTVHFPPVATQFPFRGKGIYSITGKVMVEFDCVTIEVQSMVRAAIIEDPRYSVNSENPTFQNKKSFEDNKRRIKTASLSELSIET</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBS9</accession>
    <name>A0A5C6ZBS9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA polymerase III subunit epsilon</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18885</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000034">
        <property type="protein sequence ID" value="TXD86930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006054">
        <property type="entry name" value="DnaQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Exonuclease_RNaseT/DNA_pol3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035901">
        <property type="entry name" value="GIY-YIG_endonuc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01541">
        <property type="entry name" value="GIY-YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00465">
        <property type="entry name" value="GIYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82771">
        <property type="entry name" value="SSF82771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00573">
        <property type="entry name" value="dnaq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GIY-YIG" evidence="1">
        <location>
            <begin position="199"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="460" mass="52607" checksum="8218A238C68FD27F" modified="2019-11-13" version="1">MLNNQIYTIIDVETTGRGNKMTEISIFKYDGQHVIDEFTSLVNPNAFIPAHITALTGIDNAMVADAPVFAEIAEAILRITENTIFVAHNVNFDYNIIRNEFKAIGKDFRRKKLCTVRLSRSLIPGLRSYSLGKLCKSLEIHISDRHRARGDAEATVTLFEQLLAKTEAEAVFTKFLKRDSKEATLPPHLPSRIFDAIPNETGVYFFRNKKGKIIYVGKAKNLKKRVLGHFYDKSEKELDLCRETADIDFELSGTELIALLMEDAAIKHHYPQYNKASKRPTKSFAIFSYQDRGGVWHLAFNNFKSAPNPLITFYNLRDCRLYLEQLCALFELCPKYCHLQENVQECSHFWIDTCRGICKSDEAVETYNERVQLAIAHISSASQNVVIKQKGRHEEEEAFIVVKDGLYQGYGFVEKDIQIAHDDELEPHLIKQKNNGDVQRLLKKELLKRIGKVELMQPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBX9</accession>
    <name>A0A5C6ZBX9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD(P)H-quinone oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000029">
        <property type="protein sequence ID" value="TXD87131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05276">
        <property type="entry name" value="p53_inducible_oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014189">
        <property type="entry name" value="Quinone_OxRdtase_PIG3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02824">
        <property type="entry name" value="quinone_pig3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="10"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="327" mass="35304" checksum="6A30B25CF50F5CAA" modified="2019-11-13" version="1">MKAIQFKAAGGPEVIELVEREKPKAKDHDVLIKIKAAGVNRPDVMQREGKYNPPEGVTDIPGLEVAGEIETIGENVKNFKVGDKVCAILSGGGYAEFVSVHEAQVAVLPKGLSFAEGAGLMETFLTVWSHLFKFAKFEAGKSILIHGGASGIGTTATMLCKAVGATKIFTTVSSAADQKASEALGADVAINYKTHDFVAEVKKHSNDQGVDFILDIIGGSYVQRNYAAAAKLGTILQVGIMKGKVEELNLFPMLSKRLTHLGITLRSQSLEEKSALVKELQTQVWPLIESGKLKPQLDKSFKLSETQQAHEYLDEGEHFGKIVLLND</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCM5</accession>
    <name>A0A5C6ZCM5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_17915</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000028">
        <property type="protein sequence ID" value="TXD87191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="208" mass="24921" checksum="F910A66690438BA3" modified="2019-11-13" version="1">MNWRLIVKDKTKQPKEGSYSDWKEQIAKECNYQCIYCSINEAQFGGIDHYHIEHHKPKSISRFKSLEDDICNLFYCCPICNRFKSNDWPNDADDLNIACYPDPSEYDYSELFDISSDNYKVYGIYVSTKYMTERLYLNRPQLLYERRESFLRDREQKALEAIDELLEKLNNNEDFDMLKESSRAVIDLNKTIQKRSKIRPYKLAEIRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCN9</accession>
    <name>A0A5C6ZCN9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_15200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1130" mass="123392" checksum="8119BA9D373E9472" modified="2019-11-13" version="1">MTLTTTKFSTLTNSIRFTLVAVFLFLTSGVVAQITAAPNRVITDFVVIIKDPSGGFSSGDEDTILVQLYYKGESASHQNLYIGDETFISANEMSFKIKTSLNYDQFGDLWVNNADTEINIEYLKPIKKTLSNKSSENTVTRITEIFTDYNVGTSNNPTKPRTKGFWRSSQWKDDQGNEDLKPNSNHDLLAFTYDGITYSTGVKDSRLSDNEVTFTPQKFKAYSTNGVQGKIKREHYLITGDAVDGNISTNESATITSSTIKGFGIFKSIIDGVNGLDLGTGITNFNKDVTVKFFSGNGQVGAISDNIPDLVITQIADASDGSSDIYYYADEFGSIVGRPIRLDIKKNNNEDGDGLLARWRMDLFSYSSGNFQGAIPTVFATNQTATEKTLKMVGLRLEEFEINASNIDQVNNVNMGAGGNADIAFLAYNRDAFDIKSPVATRYPVSQFICKVPNTSSSITFNTIADIDGRNVPIESIPDNQTLTYEWFKENTATSSTGSLTPATVDAPFTLSGGITINDLGTYNLKISNSFGTIILPVSLEEGGTPAIWTGGPQFNFPPVYAAAGITPSDSDRNLIFAAEYNPTTAENLEGCNCRVQAGAKVTIPIGKTLKLYSEIIIEEEVPTEYDTDGNVIANSIPAGTFTLKDGASLIQTKAVTTNANSGTINKERTANNLNKYDYVYWSSPVENFNIDGISSNTPRYLWDPAASNTGVTGVSGNYISAAGSNMEAGRGYIVRVPNTMPAYPEAGISATSTLTGRPNNGNITIDIVPTSGTYDSTISNFNLIGNPYPSAIDADKFLTDHALTSQKIEGFVYIWTHNASPTALNSPYYQDYNLNYGNQYFTYNNTGSNPSQGSSFNGKIASGQAFFVQGIQSLTTSVPLTFENDLRFDSGPNYDNNDFYRNASADSEKQLVWLNLTNANNIATTALIGYVDGATYERDVLYDAHITDDTFSLHSVLNETVLSIQGRPLPFQESDLVPLGFTISENGIYKIGIDNLKGAVFVDQEQALYVEDLYLNLSHDLRQSPYSFTAIAGTVNDRFVLRYTAPTLSTNQVTSLDTFAFINNGVLKVQSSQDIEAVQIYDLTGKAIANYIPESLSKRFSKDFNFARGLYFAVITLENGFTVKKKLLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCQ1</accession>
    <name>A0A5C6ZCQ1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19045</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000036">
        <property type="protein sequence ID" value="TXD86853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045738">
        <property type="entry name" value="DUF6088"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19570">
        <property type="entry name" value="DUF6088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="241" mass="27381" checksum="4CC21D5DDFC654E8" modified="2019-11-13" version="1">MKVAQKIETQIKTLKEGTTFKYQQLSIELNEYSAAAKAMERLIEKGTIKRVSTGIFFKPKQSIFGALKPNEEELLKPYLFQSNKRIAYITGLSLYNRMGLTTQVPRTIKIASRDKRITVSLGNIKGNPVKSYVDVTDKNFVLLEILDALKDFKKIPDLDKSAGIKIISNQLKSLSLKEIKQLMDCALSYPPRVRAFLGALLEKMDLTIELKTLKKSLNPLSEYNYGIDKKTLPTLTNWNMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCQ4</accession>
    <name>A0A5C6ZCQ4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PorT family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_15315</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025665">
        <property type="entry name" value="OMP_b-brl_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13568">
        <property type="entry name" value="OMP_b-brl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022843750" evidence="1">
        <location>
            <begin position="19"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="OMP_b-brl_2" evidence="2">
        <location>
            <begin position="52"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="206" mass="23427" checksum="7F7196AC263CE87E" modified="2019-11-13" version="1">MIKHLSFLLVFVSFSSFAQTLKVKNGISISSMDLTESEAVISGFEILNQNIVTYSFSFGLDYFESKYFYLSSEVGYLQKGGKEENEFLPSDNGARIKESWSYIHLNTTARFPIRFRNNTHIFIGAGPKLDILIDSNKFDSSIYEGYIINSTVFGAKGELGFVKDFEKIRVGLDFSYLYDFNNTGGTEFLEFKNNAYQIMASLGYKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCT1</accession>
    <name>A0A5C6ZCT1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_16815</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000024">
        <property type="protein sequence ID" value="TXD87441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="537" mass="61802" checksum="7B6ECBAEDDED61F3" modified="2019-11-13" version="1">MITSVSTHSSKLQKDIPFNKIHDFKYEIYSGDFEQQSFSLEITFSQKIKRFRDHDCKWKTVESRGIATELSPKILQMANGQIIQANHKCGIWEVSPKFPNSLFWHFNAKLAQPIVNYTGPENSKLVTSAASDLHLDVPLALLLSPDAGIELSRSKFPFTAIACFTDHCDFDTLENLKIQRQFFKTHQIKITKGFFLNQFSTRADNASWELHKEELEKWVLDGHELAYHSLSQSIKTDLESLSDFFKFKAPLNAIKVWIDHGYQPYNFSLYKKMGLEEYDFSNQLSSQHIKTLWNYIDTGTSAKGVINQLNPNHFTLKSFWDGVEGLGLKKSISLMVKNMFFHYFNDDKKIQSYKLLAVDVKAFFINKKLSALGSLMKHAFNILPAFTSVLLFWNSKKTNTYPLAIYTPLLFNHDISGHTFKVFQTLEMVDFKASLCKANIDLLCEEKGVFIAHTYFSVPLSYHHGRLLKDQNTIDKYVNANFVYLSKKIAERSIWNPTLSEFQNYIDMYKKVSFDCDEKGLIFVNGDPAIGARKVSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCY5</accession>
    <name>A0A5C6ZCY5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4 6">30S ribosomal protein S12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpsL</name>
        <name evidence="8" type="ORF">ESY86_14810</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 6">Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.</text>
    </comment>
    <comment type="function">
        <text evidence="1 4 6">With S4 and S5 plays an important role in translational accuracy.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 6">Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 4 5">Belongs to the universal ribosomal protein uS12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_010181934.1">
        <property type="nucleotide sequence ID" value="NZ_VORO01000018.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03368">
        <property type="entry name" value="Ribosomal_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00403_B">
        <property type="entry name" value="Ribosomal_S12_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006032">
        <property type="entry name" value="Ribosomal_S12/S23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005679">
        <property type="entry name" value="Ribosomal_S12_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11652">
        <property type="entry name" value="PTHR11652"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00164">
        <property type="entry name" value="Ribosom_S12_S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002133">
        <property type="entry name" value="Ribosomal_S12/S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01034">
        <property type="entry name" value="RIBOSOMALS12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00981">
        <property type="entry name" value="rpsL_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00055">
        <property type="entry name" value="RIBOSOMAL_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 5 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 6" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="4 6" id="KW-0820">tRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD87937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="124" mass="13648" checksum="301FCB03AFBD6B07" modified="2019-11-13" version="1">MPTISQLVRKGRAKITKKSKSAALDSCPQRRGVCTRVYTTTPKKPNSAMRKVARVRLTNGKEVNAYIGGEGHNLQEHSIVLVRGGRVKDLPGVRYHIVRGALDTAGVAGRTQRRSKYGAKRPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD16</accession>
    <name>A0A5C6ZD16_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Zinc ribbon domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19835</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000050">
        <property type="protein sequence ID" value="TXD86582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="219"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="242" mass="27049" checksum="A20EB3534C49295E" modified="2019-11-13" version="1">MSLVNCLECNQKISDKAIACPHCGNPMNVSVTELENSSGLLSFPNLPENLELREKIEHTTFHGHYNNNENSDLTLTKSGDVIIYSFENGVEISVNHEYGIQKLEIHKEQIISIKQTSFSEIKEIDKSVMGRALVGGLILGPIGAIVGGISGVGSNKKNIEKYYLVINYWSIDTKTIQTLLFSADKMFITSFIRVFENDLKYIEISKKVHEETGKWTKDATYGLIALIIFVVLFVIIIIGIFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD19</accession>
    <name>A0A5C6ZD19_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">30S ribosomal protein S20</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rpsT</name>
        <name evidence="9" type="ORF">ESY86_17095</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Binds directly to 16S ribosomal RNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the bacterial ribosomal protein bS20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000025">
        <property type="protein sequence ID" value="TXD87387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00500">
        <property type="entry name" value="Ribosomal_S20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002583">
        <property type="entry name" value="Ribosomal_S20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036510">
        <property type="entry name" value="Ribosomal_S20_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33398">
        <property type="entry name" value="PTHR33398"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01649">
        <property type="entry name" value="Ribosomal_S20p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46992">
        <property type="entry name" value="SSF46992"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00029">
        <property type="entry name" value="S20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 7 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="8"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD87387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="84" mass="9613" checksum="FD2A0C1644F33F59" modified="2019-11-13" version="1">MANHKSALKRIRSNESKRLTNRYQHKTTRSAIKKLREMESGNEAKEYLPEVVSMIDKLAKKNVIHDNKAANLVSNLTKHVATLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD96</accession>
    <name>A0A5C6ZD96_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RDD family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_18390</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000031">
        <property type="protein sequence ID" value="TXD87028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010432">
        <property type="entry name" value="RDD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06271">
        <property type="entry name" value="RDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="64"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="RDD" evidence="6">
        <location>
            <begin position="14"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD87028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="169" mass="18833" checksum="FF51C5A1EEC2E0B5" modified="2019-11-13" version="1">MNSRSITITTDLLASKGKRFGNFIVDYIIQMIIGAGIGVVIALMAELTGDYALYDIVVESESRLMDYVFGFGILFVYYVIIESLTSKSIGKYITQTKVVLEDGSKPGFSDILLRTLCRLIPFEQFSFLGTDGKGWHDSLSKTYVVDEKKYEAKKDTVIGLEEIGRAVEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD99</accession>
    <name>A0A5C6ZD99_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA ligase (ATP)</fullName>
            <ecNumber evidence="1">6.5.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_15985</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.1" evidence="1"/>
    <dbReference type="EMBL" id="VORO01000021">
        <property type="protein sequence ID" value="TXD87658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003910">
        <property type="term" value="F:DNA ligase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026333">
        <property type="entry name" value="ATP_dep_DNA_lig_pp_1105_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012309">
        <property type="entry name" value="DNA_ligase_ATP-dep_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012310">
        <property type="entry name" value="DNA_ligase_ATP-dep_cent"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016059">
        <property type="entry name" value="DNA_ligase_ATP-dep_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012308">
        <property type="entry name" value="DNA_ligase_ATP-dep_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036599">
        <property type="entry name" value="DNA_ligase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04679">
        <property type="entry name" value="DNA_ligase_A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01068">
        <property type="entry name" value="DNA_ligase_A_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04675">
        <property type="entry name" value="DNA_ligase_A_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117018">
        <property type="entry name" value="SSF117018"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04120">
        <property type="entry name" value="DNA_lig_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00697">
        <property type="entry name" value="DNA_LIGASE_A1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50160">
        <property type="entry name" value="DNA_LIGASE_A3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="2 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_LIGASE_A3" evidence="6">
        <location>
            <begin position="303"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD87658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="531" mass="60853" checksum="4B762884F8AC96D9" modified="2019-11-13" version="1">MKHFSKLISAVEITNKTNDKIAAFVEYFQTAPDKDKLWLIAIFTGKRPKRPIKTTVMKQWCMEVAGIPEWLFLESYSTVGDLGETMALLLPEPTHHIEKTFSHWMQEIVDLKSKSDAEKEGFVRKAWSGLETQECLIFNKLIGGSFRVGVSKKTLVNALAKFSGIEANQLMHSIIGNWDINEISFDDLLQGEHINYDNSKPYPFCLAYALEKDLTDLGDVKAWQVEYKWDGIRGQIVKRNDEIFIWSRGEELVTEQFPELVAAIERLEGDFVIDGEILALKDNAILLFNDLQKRLNRKNVTKKLLEEVPIGFYAYDLMEWNGNDMREQALAERRSLLESLFTAENTSNKTLFISEIITAETWEELIPIRAGARAKDSEGLMLKQKNSPYHTGRKKGDWWKWKVDPLTIDAVMIYAQKGSGRRSAHYTDYTFAVRKDDGLVTVAKAYSGLTNEEILEVSRFVKKNSIEKFGPVRTVKPELVFEIAFEGIALSNRHKSGVALRFPRISRWRKDKPVEEIDTIETVKQLILSPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDD6</accession>
    <name>A0A5C6ZDD6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase s41</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_17845</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000028">
        <property type="protein sequence ID" value="TXD87177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022790353" evidence="1">
        <location>
            <begin position="24"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="domain" description="TSPc" evidence="2">
        <location>
            <begin position="248"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="479" mass="54288" checksum="0BE116AFEA766C6B" modified="2019-11-13" version="1">MKQSSNLALSLCLIIMNILSLTAQDCNCEDSFAKTVETYESNYSLFMYKVTDENRNLYRAHTDIMRTKASQTETVQDCRAVLGQWLDFFRDGHTRIGISAKSRINSEKIAISEELFKSEYKGKKYEQNPLLGIWQNGGYSVAVIPNPKGSDKKRDFVGVTLESSSEDWDKNDVKFELTTNFGSSYDANFMMRDHSPEPTKAQLLSKRKLSFEGLRVWTKIWPEADVEALDSEVIRKFGEFHYTELDGIPYLRFPDFYSVGEAHVDSIMKVNHEKLIAADFIIVDVRDNGGGNDDTYYPILPYILSGPVQVPNSGLWMSNDNIRQFLDNSDLKGKSVEDYSEEERQMYDYVMSLKGTAFFQEQDYANTYEPDTLYAGPKKVILLAGDAGSSGETFVYRANQSDKVVVYGQNTAGVVDGFNGLSKDIGCFKLTYPSSFRARDVDKNPIDPYGIAPDVYVDEKVDVLTYAIEHMKQLIKDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDG2</accession>
    <name>A0A5C6ZDG2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_14205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022809408" evidence="1">
        <location>
            <begin position="22"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="154" mass="17275" checksum="0F0EA8F8982CC95A" modified="2019-11-13" version="1">MKSIVMSFLILAIGLSTYAQNQNSEMSIMKAEKPIVIINDTIIGSIDLLDKVSSDNISALTIYKDRKLSATFLFIENKKSAGLIIATIKHEFELKSQKELNIFFGLNETNDVYVNGYLIENKKQNISSESIIGIELIKADNFKLKKAVLNIEIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDQ0</accession>
    <name>A0A5C6ZDQ0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">SDR family NAD(P)-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_17215</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000026">
        <property type="protein sequence ID" value="TXD87302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="210" mass="24026" checksum="0C864B0539A4EDEC" modified="2019-11-13" version="1" fragment="single">CRKSKTPCYQGNNLHHHNQLRAATKFSEIIRFLTWVSQRRKQVVIDTNISVDKRLMEVNYLGTVGLSKALLPHYVKHKSGHFVIVSSLMGKFSSPYRSGYCGAKHALHGFFDALRMEHEKDNIKVTLICPGFVNTEVSRNALTGDGSKLNSHDTATENGLSVEDFSKRMIKAIKKEKFEAYIGKFERFGVFVKRLSPRWLHCLVKRSEVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDU8</accession>
    <name>A0A5C6ZDU8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">rRNA pseudouridine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_14745</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120159">
        <property type="term" value="F:rRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042092">
        <property type="entry name" value="PsdUridine_s_RsuA/RluB/E/F_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S4" evidence="3">
        <location>
            <begin position="75"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD87925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="306" mass="33589" checksum="5E13539D538C12E3" modified="2019-11-13" version="1">MSRHQGTGGKGKSSGNRQSKPTNKKAGARQGKSSDKGTVRGNAPIKKTSSDKAAASPSKPASPSKPSRPSNPDEIRLNKYIANSGMCSRRDADMHITVGSVSVNGEVITEMGYKVKLDDEVRFDGARINPEKKTYVLLNKPKGFATTTSQSKGRTVMDLVANATSARIQPIGRLGRNSTGLLLFTNDDVITNKFTKSKNGVSRLFEIELDKALKYEDFKKIQEGFKVAGKLVAVEEISYIHDAPKSKIGLKIKNIGNIIIHTIFDELKYEIVRIDCVAIGHLTKKDLPRGHWKHLTTQEINTLKMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDY3</accession>
    <name>A0A5C6ZDY3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2809 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000035">
        <property type="protein sequence ID" value="TXD86892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021257">
        <property type="entry name" value="DUF2809"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10990">
        <property type="entry name" value="DUF2809"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="143" mass="16553" checksum="8BB0806401841005" modified="2019-11-13" version="1">MKLKFNPYYFTATLLLFATEVCLALFLKTGFIRHSFGDYLVVVVLYCFFRSFMQLRPMYLAIFVLILAFTVEVSQLFKLLDLLQLRQNKFAAIVSGSTFSALDLIAYTLGVLSIYSIDRSYCKKQLHYKTDKTLAAKLRKNQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDY4</accession>
    <name>A0A5C6ZDY4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">30S ribosomal protein S11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">rpsK</name>
        <name evidence="9" type="ORF">ESY86_14950</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the universal ribosomal protein uS11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01310">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001971">
        <property type="entry name" value="Ribosomal_S11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019981">
        <property type="entry name" value="Ribosomal_S11_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018102">
        <property type="entry name" value="Ribosomal_S11_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036967">
        <property type="entry name" value="Ribosomal_S11_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11759">
        <property type="entry name" value="PTHR11759"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00411">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002131">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03632">
        <property type="entry name" value="uS11_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00054">
        <property type="entry name" value="RIBOSOMAL_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 7 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD87965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="127" mass="13533" checksum="430D688F8EC6B6D1" modified="2019-11-13" version="1">MAKSSTKKRKVIVEALGEAHIAASFNNILISLTNKKGDVISWSSAGKMGFRGSKKNTPYAAQLAAEDAAGVAKEAGLKKVKVYVKGPGNGRESAIRSLHNAGIEVTEIIDVTPLPHNGCRPPKRRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE12</accession>
    <name>A0A5C6ZE12_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">LD-carboxypeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_15320</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S66 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027461">
        <property type="entry name" value="Carboxypeptidase_A_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027478">
        <property type="entry name" value="LdcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040449">
        <property type="entry name" value="Peptidase_S66_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040921">
        <property type="entry name" value="Peptidase_S66C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003507">
        <property type="entry name" value="S66_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30237">
        <property type="entry name" value="PTHR30237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02016">
        <property type="entry name" value="Peptidase_S66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17676">
        <property type="entry name" value="Peptidase_S66C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028757">
        <property type="entry name" value="LD-carboxypeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141986">
        <property type="entry name" value="SSF141986"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022676844" evidence="4">
        <location>
            <begin position="25"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S66" evidence="5">
        <location>
            <begin position="46"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S66C" evidence="6">
        <location>
            <begin position="208"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="144"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="3">
        <location>
            <position position="239"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="3">
        <location>
            <position position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR028757-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD87840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="337" mass="37371" checksum="D4DBBCB303B1C8E1" modified="2019-11-13" version="1">MSKIHHLSRLCALFLFFGIATAQAQPIQSENTALIQPPYLKAGDTVAIVAPSGILQNRSDEVAHAVKLLESWGLHAVIGEHVFSQANHFAGSDAERCEDFQQALDDPKIAAIWCARGGYGTVRILDKLDYTKFKKHPKWLIGYSDITALHNQFHNEGYQTLHALMCTSLPRDISEIEQTVGTFKSALFGMPENYTLKGSADNRIGKATGELVGGNLTILHTMLGSETSIDTSGKILFIEEIGEYKYHIDRMLQSLKRAGYFDDCAGVLVGDMTRLRTNTTLWGSSVEQLILDALAEYDFPIAFNMPAGHEDDNRAMIFGRVVELNVNKEKSSIRYAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEE9</accession>
    <name>A0A5C6ZEE9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">30S ribosomal protein S7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 10" type="primary">rpsG</name>
        <name evidence="10" type="ORF">ESY86_14815</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the universal ribosomal protein uS7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.455.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00480_B">
        <property type="entry name" value="Ribosomal_S7_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000235">
        <property type="entry name" value="Ribosomal_S5/S7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005717">
        <property type="entry name" value="Ribosomal_S7_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020606">
        <property type="entry name" value="Ribosomal_S7_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023798">
        <property type="entry name" value="Ribosomal_S7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036823">
        <property type="entry name" value="Ribosomal_S7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11205">
        <property type="entry name" value="PTHR11205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00177">
        <property type="entry name" value="Ribosomal_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002122">
        <property type="entry name" value="RPS7p_RPS7a_RPS5e_RPS7o"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47973">
        <property type="entry name" value="SSF47973"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01029">
        <property type="entry name" value="rpsG_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00052">
        <property type="entry name" value="RIBOSOMAL_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6 8" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="6" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_S7" evidence="9">
        <location>
            <begin position="2"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD87938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="158" mass="18311" checksum="401460128A4E8F13" modified="2019-11-13" version="1">MRKRAAKKRPLLPDPRFNDQLVTRFVNMMMWDGKKSVAFKVFYDAIDIVESKKTDEEKTALEVWKDALSNVMPHVEVRSRRVGGATFQIPMQIRPDRKVSTAMKWLISYSRKRNEKSMPQKLAAEIIAAAKEEGAAVKKRVDTHRMAEANKAFSHFRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEF0</accession>
    <name>A0A5C6ZEF0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Aminotransferase class V-fold PLP-dependent enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_16540</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4 5">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the group II decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000023">
        <property type="protein sequence ID" value="TXD87502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021115">
        <property type="entry name" value="Pyridoxal-P_BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00392">
        <property type="entry name" value="DDC_GAD_HDC_YDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="3 5" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="4">
        <location>
            <position position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR602129-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD87502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="468" mass="52208" checksum="19263EAD2E96BCEC" modified="2019-11-13" version="1">MLNDLKLFQELTEILLTEERETPVAKPIPSQHLYDSIDLSLPEDASIDNDFKATLTELIKRTPKTASTSFFNQLFGGRISRATLGDLLAVMLNNSMYTYKVAGPQVGVEKVLLRKICDMIGYTATSDGTFAPGGSMSNFMAVLMARDKYNPEAKTEGMSHKMTLYTSECSHYSIAKNAAFIGVGRNQVKAIKVNAVGEMIPSELDLQIKKDIAANLQPFFVNATAGTTVLGAFDDVEAISKVCKAHDLWLHLDGAYCGSVIFSDAYKHLVKGIALTDSFSVNAHKMLGTPLSCSIIVAKDKKHLYQSFSNDAEYLYQTNDDDYNLGKTSIQCGRRNDALKLWTLWKSVGSKGLEKIVAHQFMIADVARKYIKNHPDYTLYSFDDSISVCFNYKDIPAKTLCTQLYEQAALMVGFGKFKEQEFVRLVTINSLIQEQDMIAFFKTIEAFEFENKPENKELVGNSQVIDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEG2</accession>
    <name>A0A5C6ZEG2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_12940</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039426">
        <property type="entry name" value="BtuB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041700">
        <property type="entry name" value="OMP_b-brl_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30069">
        <property type="entry name" value="PTHR30069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14905">
        <property type="entry name" value="OMP_b-brl_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023090685" evidence="1">
        <location>
            <begin position="22"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="domain" description="OMP_b-brl_3" evidence="2">
        <location>
            <begin position="380"/>
            <end position="779"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="803" mass="91391" checksum="A1F9E44CE24B38C4" modified="2019-11-13" version="1">MFHLKTYFLFLTLSATLFCFSQEYSISGTVLDTNGQPIEFANVFLVSEDAETVIKGISTDDKGFFMLKNLPKNTYILKASFIGFDGHQETIVLTEDLKLEPIMLQESSENLDQVSITVKKPSLIREADRLIFNVQNTALVEGSMLDVLKNTPGVLVVDDAITIKSATPTIYINDKQVYLSSADLNQLLDGSSANSVTSVEVITNPSARYDAASGVVLNIKMSKNLIAGYRGSLSANYTQGVFPRYDFGSNNFFKNKKISFNINYNYSKDKINRDGDDTVNYLDDTNSLDQSWRSRTNRNTKSETHSLNANFDYFIDDTHTLSFSANTFYLPYFRYSIDNNTIITDENANFLSRFTADNLSRDDKYNLGFDLNFNRRLSKGQLLFNAHFTTYNYERNQGVLSNFYDGNNTFDNASAFNTNANQDTEIFTSKLDYNVPLNDKSSFETGVKYASTRTVSDLTQFDVNLNTGAESLNTLNSDVFDYDERIYAAYANYSLNTDKWSISTGLRVEQTNIEGVSAATSIENIQDYLEWFPNASVQYNLTDNYNVYTNYKRSISRPGYADLNPFRFFLNENYVVSGNPNLVPTFIDHVVVGAGLLNMFTVEAYYKNLDGAISEIPRQDNNTNIIEYINVNFDKTIEFGFDFATYFNVTDRWYLYAVTSFFNLEEETDFGNGVVNQNQWSNLSILQNSISFLEDNSLSATLSLTYYGNHLEAFQTVDERLFSELSVVKSVLDKKGVVSLSVGDIFNAQDIRTRVRYQNQFSFGKSDIDNRYIKVGFRYKFGNTRLETNERSIDLEELKRLDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEI4</accession>
    <name>A0A5C6ZEI4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17885</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000028">
        <property type="protein sequence ID" value="TXD87185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="94" mass="10808" checksum="F3CF25F40C6265A6" modified="2019-11-13" version="1">MKRFEIYKNIRKRAVIFGLPISLFALMMVAILVSLLVIIFSFSFGMVIGILIFNAGLYIALTRINQNPQLFQMAKAFPRIISNKRNSGFDYEQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEX7</accession>
    <name>A0A5C6ZEX7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="77" mass="8991" checksum="E374EDC4ECFAE0F1" modified="2019-11-13" version="1">MTKKTKLRILCYLAFFIIFITIWTILHFTFENLGAPYKGMISAVVSAIFAPRINEYKNQSGNQVQLKWFFSRKPVSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF09</accession>
    <name>A0A5C6ZF09_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">M28 family peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12930</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="PTHR12147"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="1">
        <location>
            <begin position="330"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="411" mass="45287" checksum="C9F040BC848C6DB0" modified="2019-11-13" version="1">MKNIVLILFLTVLIACKPNSEEKSKPVSIKEDVSFLADDKLEGRQTGTKGEKAAADYIAMRFETMGLEAKGTDGYFQQFLFKPKTDPHQEVKYNVKDGDSTITGINVIGFLDNNAKNTIIIGAHYDHLGYGAEGSLYRDKEQQIHNGADDNASGVAVMLNLAQKLKSANTGNNYLFMAFSGEEMGLLGSNYFTKNATIDFQNANYMINMDMVGRLKNNNTLAVYGLGTSPILKQVVKANNANFKIIENESGVGPSDHTSFYLADIPVLHFFTGQHEDYHKPGDDTEKLNIEGMALISGYIFDIISDLDDNGKLPFRKTKNESEDVPRFKVTLGVVPDYLFDGKGMRIDGISEDKPAQKAGLQKGDVVVKLGDSLVTDMMSYMRALSAFDTGDKTKVVVKRGEEEVEAALEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF26</accession>
    <name>A0A5C6ZF26_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">T9SS type A sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_13985</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022899646" evidence="1">
        <location>
            <begin position="20"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="domain" description="Por_Secre_tail" evidence="2">
        <location>
            <begin position="504"/>
            <end position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="574" mass="60139" checksum="F4F3A9C5AD0B48AA" modified="2019-11-13" version="1">MKKLYFLALTFMIGFASFGQNPIITSIVDGDCSGGNPKLLEIYANGTVDFADYSLENQTNANVTWGNAQDLSSFGEVTNDFVYISISSSTDAIATEFPSLASAPVLITNTMSVNGDDRVRIILTASTTVIDQYGVDTVDGSGESWEYADSYAKRVNGTGPDSSFNAANWTFGGAGALNGLGTCQGGADTFETLIGGVGTYTITQNTEPAINILSPANGATLAPGTTTVNVEFTTNNLSGTETVNITVNGSTTNGVTSPFEITATDGESYDVTVDLVDGGILDSDTISFSVLSSNTVANIAALRAGASGEVYELTGEVLLTYQQSFRNQKFVEDATGAILIDDPSGVMSTAYNIADGITGIVGTLSEFGGTLQFTPIEDSAAASSTANALTPQAVTLAMLSANAENYESELVTITAVTMDNTEPTFVTGTEYELTQGQGAETFNFRTAFFSADYIGANVPTMVTDITGILTERSGNAYYITARDADDFSVAVLSVSQFDATSVVVYPNPTSTGFVNITSANNDAISVTVFDILGKSVINQTLTHDRLNVSALNSGIYILKISQNKASVTKKLVIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF70</accession>
    <name>A0A5C6ZF70_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lauroyl acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_12170</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008915">
        <property type="term" value="F:lipid-A-disaccharide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011499">
        <property type="entry name" value="Lipid_A_biosynth_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07578">
        <property type="entry name" value="LAB_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01259">
        <property type="entry name" value="LAB_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="156"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="LAB_N" evidence="2">
        <location>
            <begin position="9"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="LAB_N" evidence="2">
        <location>
            <begin position="130"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="212" mass="25000" checksum="5661A9728246A6DD" modified="2019-11-13" version="1">MSNWMIYGIGFIAQILFSSRLIIQWIASEKQKRVITPTLFWALSLLASVLLFVYGYLRYDFSIMLGQSLTYYIYIRNLQLQKQWQKYPTAVRWFLLVFPALIVIYYFNNNKIDVNLLFKNEAIPFWLLGLGIIAQVIFTLRFVYQWFYSEIRKTSSLPFGFWLLSLVGSMLILTYAIIREDWVLILGHGLGSIIYTRNIYLIQKANAKEAIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF85</accession>
    <name>A0A5C6ZF85_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Gamma carbonic anhydrase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_14645</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="170" mass="18052" checksum="C5BD81959BFD2830" modified="2019-11-13" version="1">MPIIKSIKDKSPQIPSDCFIAENATIIGDVTLGNQCSVWFNAVIRGDVHFIKIGNKVNVQDGAVIHATYQKSPTTIGDNVSIGHNAIVHGCTIHDNVLIGMGSIVMDDCIVESNSIIAAGAVVTKNTVVASGSIYAGVPAKKVKDISAELISGEINRIADNYVEYSSWLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFF8</accession>
    <name>A0A5C6ZFF8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carboxypeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_13510</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018202">
        <property type="entry name" value="Ser_caboxypep_ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="PTHR11802"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00131">
        <property type="entry name" value="CARBOXYPEPT_SER_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022961351" evidence="1">
        <location>
            <begin position="21"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="498" mass="56395" checksum="49EB3DDF467A1EC8" modified="2019-11-13" version="1">MQLLKKFTFLLVLSSFAIQAQEIRIPADTTITTQHSAKINGNILEYTATTGMQPVWNSDHKAMATLHYTFYKKNVKNTSEEPQRPLLISFNGGPGSASAWMHIAYTGPKILKISPEGYPVQPYGLKDNPHSILDVADILYVNPVNTGYSRTLDIDGKAPDRDLFFGVNADIKYLASWLENFVSRNNLWLSPKYLIGESYGGTRVSGLALALQEQQWMYLNGVILVSPADYLSFDSDTALSSSLFLPYFTAAAWYHKALSPALQQQTLEAILPEVETYALDVLLPALAKGSLLSTSEKEKIAQQMATYTGISEKIILQHNLDLPSRSFWKELLRDKSGNTIGRLDSRYLGIDRKLAGDGPDYSPELTSWLHSFTPAINYYMREELNFKTDLSYNMFGSVRPWDNRGNNTREDLRQAMATNPYLNILFQTGYYDGATTYFHSKYSMSQIDPSGQLKDRMHFKIYHSGHMMYLRQEDLKTSNDDLRAFLKQTNQKGKTAKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFJ6</accession>
    <name>A0A5C6ZFJ6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11735</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="62" mass="6753" checksum="9EB1D8F910A48882" modified="2019-11-13" version="1">MIITITLILSFLVALNFLLLIFSCNRHSKVKKLSENGILSKPKELSVPTKELATAQLAPTGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFL4</accession>
    <name>A0A5C6ZFL4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">UDP-glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_16835</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000024">
        <property type="protein sequence ID" value="TXD87475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="463" mass="53960" checksum="0A414FFAE731E94D" modified="2019-11-13" version="1">MTSKKVFLLLPDGVGLRNFAYTDFNKVGKAAGFEITYWNNTPFDLASLGFEAIDITKPKTHPLTETYKNARKHVELNLFIKRFEDRTYDSYRFPFSNKTFKQKVKTFLTKRLISKHTTESGHRILVKKITDFESSTFYFRQCLETLKKEQPDFVFCTSQRSILAIAPIQAAKKLGIPTATFIFSWDNLPKATMVVDTDYYVVWSTLMKEELLKYYPDITSDQIVITGTPQFENHFNARLKDSKEDFYNKHRLDLNKRYICYSGDDITTSPNDPHYLKDTAQAVRLLNQKGFNLGIVFRRCPVDFSTRFDTVLKEYQDVIMPIAPLWKKLGTIWDTVLPTQEDMTLQTNTIAHTEFVINLGSSMVFDYACYQKPCVYINYDIPNPSSTWSVQKIYKYIHFRSMPSRDAVVWFNDVTEIEIKIRNILENKLSTTVNANAWFKTINQFPPEKASERIWDFIKNATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFM9</accession>
    <name>A0A5C6ZFM9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Polyprenyl synthetase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_14220</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00685">
        <property type="entry name" value="Trans_IPPS_HT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00723">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00444">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="325" mass="37041" checksum="878125A4EEE45D03" modified="2019-11-13" version="1">MKITEQIKQPIAYEMELFEQKFQLAMSSKVALLNRITHYIVNRKGKQMRPMFVFLVAKMVDNGQVSERTYRGAAVIELIHTATLVHDDVVDDSNRRRGFFSINALWKNKIAVLIGDYLLSKGLLLSIDNNDFDLLKIISVAVREMSEGELLQIEKARQLDITEAIYYDIIRQKTATLIAACCSLGAASVKPNAPDVETMRKFGELIGMAFQIKDDLFDYGTEAIGKPTGIDIKEQKMTLPLIHVLNNCTKKEKSWIINSVKNHNRDKKRVKEVITFVKANGGLDYAVNTMKRFQAEALELLRTYPASEFRSALELMVNYVIERKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFQ5</accession>
    <name>A0A5C6ZFQ5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DoxX family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15910</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000021">
        <property type="protein sequence ID" value="TXD87645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="124" mass="13877" checksum="56CA2CBDDB2BD233" modified="2019-11-13" version="1">MNTTFFLIIRVVFGLFLLFFGFDHFFSYIPFPAMAPEANAYFANLSATGAMQLVGIVEIVSALAFIFNKYGALMAVILMSVSINAVLFHVALDPAKIYGALLLLILNVAMLYFYRNKYKQLLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFW0</accession>
    <name>A0A5C6ZFW0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_10635</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="134" mass="15088" checksum="F88120CA88227E16" modified="2019-11-13" version="1">MIENLRKEFIQEAKAAPKLFKDLAKVEQYIAESYKTRALIELMQNADDAEASKFGIHSFNNGFIVGNNGKPFTQNDVEALCRSGSSNKHRGGETIGYRGIGFKSVVNIANVVNIISGNFKFSFERKKRYKHLII</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFZ4</accession>
    <name>A0A5C6ZFZ4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uroporphyrinogen-III synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_13945</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004852">
        <property type="term" value="F:uroporphyrinogen-III synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006780">
        <property type="term" value="P:uroporphyrinogen III biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06578">
        <property type="entry name" value="HemD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10090">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036108">
        <property type="entry name" value="4pyrrol_syn_uPrphyn_synt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003754">
        <property type="entry name" value="4pyrrol_synth_uPrphyn_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039793">
        <property type="entry name" value="UROS/Hem4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12390">
        <property type="entry name" value="PTHR12390"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02602">
        <property type="entry name" value="HEM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69618">
        <property type="entry name" value="SSF69618"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HEM4" evidence="1">
        <location>
            <begin position="27"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="250" mass="29077" checksum="FBDDBBCCA4751D90" modified="2019-11-13" version="1">MTKVKTILVSQPEPKIENSPYFDLQEKQKVKIDFRPFIHVEGVDAKEVRQQKVDLSHYTAIILTSRNSVDHFFRVADEMRFKVPDSLKYFCQSEAVAYYLQKYVVYRKRKIYVGKRTFSDLTSLIKKYKDEHFLLPTTDKLKPEVPETLDGLNVKWKQAVFYKTVISDLSDLENVTYDILVFFSPSGIESLFHNFPGFKQNETRIAVFGNTTIKAVEDHGLRVDIAAPTPETPSMTMALDKYIDKMNKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG81</accession>
    <name>A0A5C6ZG81_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005496">
        <property type="entry name" value="Integral_membrane_TerC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03741">
        <property type="entry name" value="TerC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="111" mass="12428" checksum="BD58CA5147E183F7" modified="2019-11-13" version="1">MTNGLHPNHNYTLVLMIIAVVISIVIMIAFANPIRRFIDKNPSIQMLGLAFLILIGFMLITEAAHLSNTQFFGNTVGAIPKGYLYFAIAFSLFVEFLNFKMSEKKSSKKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG88</accession>
    <name>A0A5C6ZG88_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyl hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_16005</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000021">
        <property type="protein sequence ID" value="TXD87662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000490">
        <property type="entry name" value="Glyco_hydro_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00332">
        <property type="entry name" value="Glyco_hydro_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="302" mass="34488" checksum="713C8224C9D370C6" modified="2019-11-13" version="1">MSYRRANDYVLKHADYSEQVGVDYSNYSEDKLKDLWRTTIKNGMHGLCFSMYEDGQTPGNIITEVQVERRIKIIKPYTQWVRSFSCIEGNEHIPRIAKRQGMKTLVGAWLSSDKKENEKEINGLIELGKAGVVDIAAVGNEVLYRKDLTLEELLGYIKRVKQALPDVTVGYVDAYYEFTVHPELVDVSDVVLANCYPYWEGCHIDHALSHMQQMYGQAIDAGRGKKVIITETGWPSQGGSLDAAMSSEENAMRYFINTQKWSANDNIDVFYFSSFDESWKTGDEGDVGAFWGLWDKHEKLKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGH0</accession>
    <name>A0A5C6ZGH0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RtcB family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_12770</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="3">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008452">
        <property type="term" value="F:RNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001233">
        <property type="entry name" value="RtcB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036025">
        <property type="entry name" value="RtcB-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01139">
        <property type="entry name" value="RtcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103365">
        <property type="entry name" value="SSF103365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="GMP-histidine intermediate" evidence="1">
        <location>
            <position position="367"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="225"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="309"/>
            <end position="310"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="309"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="343"/>
            <end position="346"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="367"/>
            <end position="370"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="467" mass="52282" checksum="AEFF44F7B3F1B637" modified="2019-11-13" version="1">MSTEKKITGNDLVAMGFRRGKWMKDAIAHINTNRLEAEAMLQYLEQFKLPAGIELHTKPIGFAVNIKADSDLEQDNVFKVVNSMKTLMKTPTLVNGALMPDACPTGPDGTIPVGGIAVAKNAIHPGMHSADICCSVMLTDFGKINPKTILDAAHAKTHFGPGGRDRDSQFQLPTALSEAFEHNNLLNDKQMISIARSHLGTQGDGNHFLFVGTSKKTGNTMLVTHHGSRGPGARLYDKGMKIAERFRKELSPDTMKQNAWIPFHTEEGKTYWEALQVIRQWTKTNHEVLHNSVAESLEITIENRYWNEHNFVFRDGDLFYHAKGATPLDAKFMPDITGPRLIPLNMSEPVLIVEGVTTGSNLGFAPHGAGRNVSRTQHRKNKTGTIMQIFKEETKGLDVRFFSKEIDITELPSAYKNANSVRQQMDEFSLGTVIDEVMPYGCIMAGDWQKNAPWRKKRDKRQKRRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGI2</accession>
    <name>A0A5C6ZGI2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">VWA domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_11330</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13519">
        <property type="entry name" value="VWA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="185"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="115"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="375" mass="42706" checksum="7BDC5C0584C375A5" modified="2019-11-13" version="1">MKKENKHKKGFVFKPYEAPNQSPFDKLFEIFKELITHTSGDFDEAIDWLKQLDKEYELTTAEYTIDDFIEDLKKKGYIKEEIDIDGKGGMAITAKTERAIRQQALNQIFGALRKSGRGNHQSKSPGIGDEHTGDFRDYQFGDALDKVSMTESLKNAQINHGIGDFSISEDDLVVEETMHKSQMSTVLMIDISHSMILYGEDRITPAKKVAMALAELITSRYPKDTLDIIVFGNDSWQIEIADLPYLKVGPYHTNTVAGLQLALDLLRRKRNTNKQIFMITDGKPSCLRLPDGQYYKDSNGLNPHITNKCYAMAGQARKLHIPITTFMIAQDPYLMQFVQEFTKANQGKAFYTGLKGLGEMIFEDYETNRKKRIRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGI3</accession>
    <name>A0A5C6ZGI3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_15850</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="126" mass="14914" checksum="706116F58E583C8C" modified="2019-11-13" version="1">MDSFIEIRFKKETAKRFQEFSRTHFKSHTETMATMLDFFFYNEISPKEKLGPTGRTIEAKLLKRINAVIAIMRDVEKTQTKPTVAMIQSLFQTEVPVKKPLILEKKYAEEKKEIRFREKQNPSNQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGK1</accession>
    <name>A0A5C6ZGK1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">T9SS type A sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_09700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022749892" evidence="1">
        <location>
            <begin position="19"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="Por_Secre_tail" evidence="2">
        <location>
            <begin position="199"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="255" mass="28171" checksum="6298228C87687E08" modified="2019-11-13" version="1">MKKITYFVLLLITTSLFAQNAAQDAAAITNFKLKLSNETQDYLTDIYFSEYSSLGLDPGYDAAFFGSPTTGFSLYTQLVESNEGIPFTIQAVGETDYNDVTIPLGVNAELGVEVRFSIQTSSIPETVAVYLDDTVANTSTLLTETDYVLTPSSDLMGVGRFYLRFVGENLATTHRSFSDLSIIMANNTKELIIKGQLKAATVCTVFDINGRLISKYALDIHQNENRLSLQTMNAGVYIIKIKDQKQENAMKVIID</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGL9</accession>
    <name>A0A5C6ZGL9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Prepilin-type N-terminal cleavage/methylation domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_09450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012902">
        <property type="entry name" value="N_methyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02532">
        <property type="entry name" value="IV_pilin_GFxxxE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="131" mass="14755" checksum="7FF419D2A3AC1D24" modified="2019-11-13" version="1">MKKLPAYNLQEILVVLVIIGILLLLALPNLMPLISKAKSTEAQLQLSHIYNSQTTYRYMYSKYSMDLSDIDFEAPKTVNNNGRSNYAYEILSATNNSFKARATAITDFDGDGIFNVWEIDENGAPKQIVKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGQ5</accession>
    <name>A0A5C6ZGQ5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Translocation/assembly module TamB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_09210</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007452">
        <property type="entry name" value="TamB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04357">
        <property type="entry name" value="TamB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1628"/>
            <end position="1659"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD89303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1659" mass="183037" checksum="5735375D11AE8A70" modified="2019-11-13" version="1">MVLFVRSPWGQGIIVDKVVNFVSDKTNTKVAIDRLFITFDGDVQLDGLYLEDTKGDTLIYSKSLEANIPLWATINGEAVGVEALDWEGLRANIIRKDSVNGYNFQFLIDAFVAADTTSVATDTTSTPLNLILKNLNLKDIDIVFNDAVIGIASKYKIGELKAGMETIDLEQMIFNASELELTNANIQFIQNPAVTDTTSTDVPLPKLSAESLKLQNVKAYYQSKPNQVIADLDIGQFYTEIPQINLANSEFILDQILLKDSKILFHTETETKLADKKPKPENQSKTEGSKAFEWPAIEVSVADIDFENNKLTYLVGDARPVSGEFNPNAVAIEDLSLQAKDLYLRDEAAGLELNQFDFKEFSGFNLKQLAFKFELTNQQLHFEDLKFQLNDNSIQGYVELNYSSISKLMQQPENTKVQLNLPSFSLSLKELFKFQPSLEENEYLKTLSKKQIRGNINAAGTLAAINFPNININWGKNTKISASGKVFNPTNPKKLAFDIPQFSAETTRETAQLFLNEQDMGITFPKNVRLAGTAKGNLEDLSAEAKLTTTQGVATIGGDFKNAANIAFDLNLTIDDYKVNELLNNPQFGALTLNVKAEGSGKTINTLDATLDANITSFQLKGYAINDLNINGKLKNGQGHVRSNYKDDNLNANLDALVVLDSIAPEATLELDVVGANLQALGLMNRDVRAGLKLYADFKGNAKNYDVSAIIEDGVVVYDNKSYLLGAFDALAHVTQDTTSVSIRNKMLDLKLESNTDPQTFSKALQLHVSSYFSRKTKRLDTLKNPVNLKIEAKIAESPLLNDVFLVNVKELDTINVAVDFNQKARKLKANITAPHINYSGNKLDSLVFAMDTDEDNFKFDFGFKNLSAGPLDIPSTRISGNQTNNELSLNISGSNKGTQLMNVNSKITGNSERLRFHVSPDSLILNKKKWTIPEDNEVIITQSKLEFNAFEISRDNQSINITNKLAGIDKNHIAIEFSNFNIQEVFNYLNPDSQLAKGELNGNFVIEAPFKETGIVADLNIQEFQVLKSDLGTLSLDAKSLGNNSYDFEADMKGGDVDLDLKGDYIASTGGGNLDLDLKINKFKMEALNDLSMGEIKNASGNFSGQFKLTGETSDLQYQGSLNFNEAKFNVAKLNTDFLLKDETLNIDNAGLSMSNFTVLDANNNALVVSGEIGTERFINPTFNLDLKATNFQVLDATKEDNEMIYGKAAFDVNAKLTGDLQLPKLNAKLSLNSSTDVTYVLPSSVANVETRDGVVVFVNRENPDAILTQTKEETATVRGFDVSALIKINKNATATIIIDEDTGDNFKIKGEGDLNLTMSPNGRINLTGAYEISDGHYELTLYNLVNRKFNIAPGSRVTWSGDPFDAKLDVRAIYNIETSASPLMAAGISGSDATVKSKFRQVLPFNVYLNIDGDLMQPKISFQLDMPEEEQGAVGGQVYSRVQQVNQQESELNQQVFSLLVLNKFYPNSGSDGSSGGFANVARDNLNDAVSDQLNTFSDQVLGSSGIDLDFGLDSYTDYQGESPTQRTQLDVAAQKKLFDDRLIVRVGSQLDIQGSGAPGEQAPLVGNVSLEYLLTENGRYRLKGFRKSEFENVIDGQTIVSGIALIFTQEFNQFKDLWDAMLRSQSKKDEAEAEQAKQEIEKKQEATEKSMENKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGU8</accession>
    <name>A0A5C6ZGU8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GTPase Obg</fullName>
            <ecNumber evidence="5">3.6.5.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">GTP-binding protein Obg</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">obgE</name>
        <name evidence="5" type="synonym">obg</name>
        <name evidence="9" type="ORF">ESY86_12455</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.-" evidence="5"/>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01898">
        <property type="entry name" value="Obg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.210.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01454">
        <property type="entry name" value="GTPase_Obg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014100">
        <property type="entry name" value="GTP-bd_Obg/CgtA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006074">
        <property type="entry name" value="GTP1-OBG_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006169">
        <property type="entry name" value="GTP1_OBG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036726">
        <property type="entry name" value="GTP1_OBG_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045086">
        <property type="entry name" value="OBG_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11702">
        <property type="entry name" value="PTHR11702"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01018">
        <property type="entry name" value="GTP1_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002401">
        <property type="entry name" value="GTP_bd_Obg/CgtA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82051">
        <property type="entry name" value="SSF82051"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02729">
        <property type="entry name" value="Obg_CgtA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00905">
        <property type="entry name" value="GTP1_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51883">
        <property type="entry name" value="OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Obg" evidence="8">
        <location>
            <begin position="4"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="OBG-type G" evidence="7">
        <location>
            <begin position="163"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="69"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="169"/>
            <end position="176"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="194"/>
            <end position="198"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="216"/>
            <end position="219"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="283"/>
            <end position="286"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="312"/>
            <end position="314"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD88544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="332" mass="36818" checksum="08E8E862AFE52548" modified="2019-11-13" version="1">MTEGNFVDYIKMHVSSGKGGQGSAHLHREKFIEKGGPDGGDGGRGGHIILRGNSNLWTLLHLKFKRHARAGHGGNGSKSRSSGADGEDVYLDVPLGTVVKDTETEEVLFEITEDHEERIVAQGGRGGLGNWHFKSSTNQTPRYAQPGEPLNESDITLELKILADVGLVGFPNAGKSTLLSVVTSAKPKIADYEFTTLKPNLGIVEYRDFQTFVMADIPGIIEGAAEGKGLGHYFLRHIERNSILLFLIPADAKDIRKQYDILLDELKRYNPEMLDKERMIAISKSDMLDEELQAELKQELDKTLPINYMFISSIAQKGIVELKDKLWKMLND</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH10</accession>
    <name>A0A5C6ZH10_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 8">Transcription elongation factor GreA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Transcript cleavage factor GreA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 11" type="primary">greA</name>
        <name evidence="11" type="ORF">ESY86_08560</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7 8">Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the GreA/GreB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070063">
        <property type="term" value="F:RNA polymerase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032784">
        <property type="term" value="P:regulation of DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00105">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036953">
        <property type="entry name" value="GreA/GreB_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018151">
        <property type="entry name" value="TF_GreA/GreB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006359">
        <property type="entry name" value="Tscrpt_elong_fac_GreA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028624">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001437">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023459">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022691">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036805">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30437">
        <property type="entry name" value="PTHR30437"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01272">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03449">
        <property type="entry name" value="GreA_GreB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006092">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46557">
        <property type="entry name" value="SSF46557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01462">
        <property type="entry name" value="greA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00830">
        <property type="entry name" value="GREAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 7 8" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="GreA_GreB_N" evidence="10">
        <location>
            <begin position="6"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="GreA_GreB" evidence="9">
        <location>
            <begin position="87"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD89425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="157" mass="16970" checksum="84DD508AA1042F66" modified="2019-11-13" version="1">MSKVSYYTAEGLKKLRDELSHLKDVERAKASQAIAEARDKGDLSENAEYDAAKEAQGMLEMKISKLDAQLSGARLIDESQMDVTKALVLSKVRLKNQNNGMEMTYTLVADGEADLAAGKISVNSPIGKGLLGKSVGDIAEVQVPNGVIKFDILEISR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH50</accession>
    <name>A0A5C6ZH50_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Alanine--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Alanyl-tRNA synthetase</fullName>
            <shortName evidence="9">AlaRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 11" type="primary">alaS</name>
        <name evidence="11" type="ORF">ESY86_12310</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala)</text>
            <dbReference type="Rhea" id="RHEA:12540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9657"/>
            <dbReference type="Rhea" id="RHEA-COMP:9923"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78497"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="9">Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.7" evidence="9"/>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004813">
        <property type="term" value="F:alanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006419">
        <property type="term" value="P:alanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00036_B">
        <property type="entry name" value="Ala_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002318">
        <property type="entry name" value="Ala-tRNA-lgiase_IIc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018162">
        <property type="entry name" value="Ala-tRNA-ligase_IIc_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018165">
        <property type="entry name" value="Ala-tRNA-synth_IIc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018164">
        <property type="entry name" value="Ala-tRNA-synth_IIc_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023033">
        <property type="entry name" value="Ala_tRNA_ligase_euk/bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003156">
        <property type="entry name" value="DHHA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02272">
        <property type="entry name" value="DHHA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01411">
        <property type="entry name" value="tRNA-synt_2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00980">
        <property type="entry name" value="TRNASYNTHALA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101353">
        <property type="entry name" value="SSF101353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="SSF55186"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00344">
        <property type="entry name" value="alaS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50860">
        <property type="entry name" value="AA_TRNA_LIGASE_II_ALA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 9 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 9" id="KW-0820">tRNA-binding</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II_ALA" evidence="10">
        <location>
            <begin position="1"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="572"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="576"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="674"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="678"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD88520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="880" mass="99760" checksum="240A85833FA9A774" modified="2019-11-13" version="1">MKSQDIRQTFLQFFKDKAHSIVPSASMVLKDDPTLMFVNSGMAPFKEYFLGNAQPKNKRITDSQKCLRVSGKHNDLEEVGYDTYHHTLFEMLGNWSFGDYFKTEAISWAWELLTEKFEIDKESLYVTVFEGDEGDKTPMDQEAYDIWKNLISEDRILMGNKNDNFWEMGDQGPCGPCSEIHVDIRSAEEKAKIDGKTLVNQDHPQVVEIWNLVFMQYNRKANGNLENLPDKHIDTGMGFERLCMVMQGVQSNYDTDVFTPIIREIETITDKKYIPVRTSRDLSVRDEKIAIAIRVISDHVRAVTFSIADGQLPSNTGAGYVIRRILRRAIRYGFTFLDQKEPFIYRLVDVLVKKMGHAFPELKSQRQLIENVIKEEEASFLRTLEQGLVMLDNIVKHAATKEISGAKVFELKDTYGFPEDLTELILREHKLSYNKTEFDQQLKAQRQRGKQASELKSDDWTVLMEDQIQEFIGYDALEAKVKLTRYRKVSSKKDGDMYQLVFNLTPFYAEGGGQVGDKGYLEDSQGDIVYIVDTKKENNVVVHFTKSLPKNLQETLKATVDAKQRYRTECNHTATHLLHQALREILGTHVEQKGSAVHSKYLRFDFSHFAKLTVEELSDVEDFVNARIYGKLDLQEQRNIPMQKAIDEGAMALFGEKYGDTVRTVRFGQSMELCGGTHVANTAHIWHFKITAESAVAAGIRRIEAITSDAVKGYFQEHDKAFMEMKHLLNNAQEPIKALQNLQDENSSLKKQIEGLLKEKAKSIKGDLKNELSEINGVHFLAKKIDLDASGIKDLCFELGSQFDNLFLLFAAENDGKAILSCYISKELVASKNLNAGTIVRELGKHIEGGGGGQPFFATAGGKNPAGIAEALRAAEGYLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH78</accession>
    <name>A0A5C6ZH78_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_14150</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023046029" evidence="2">
        <location>
            <begin position="23"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="51"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="220"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="289"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="378" mass="44621" checksum="3B9DEAC1B00DBC73" modified="2019-11-13" version="1">MRKRFFIRLLVLLLGYASQAQMGVMSTADSLYGHGNFTKAIYVYKTLEDQDLVADKIAKSYLAIGNYDAALNYYKQRVEAHPDDALSIYEYAKLLSRTKHYEASIAQFNTLMNIDFRNPNYHYEMGLALDRMDDSTAIDRFIAAYKLDDTHQKAIFKIGKYYLKKRKHEIANQYIDKGLESYANNLELISLKAQNYYYHYDYKNAQIWFEKLLEMGESSEFIHEKLSMVYAEFSEFEKAIEQRKLALKFNPLDATALFVIGTYYEKLEDFATAESYIQQSLKLKDVPLDFEYQKLGFVLNRQNKFKEAIKAFQTSIKEDPENVASEFYLLITKDKYYADYDAKVKLYEDFLKKHQDAMFSEFAKKRLKELKDERFMKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHB4</accession>
    <name>A0A5C6ZHB4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07155</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="160" mass="18961" checksum="56F03EF4F035950B" modified="2019-11-13" version="1">MKINYLFPNKFKKMGWFILIPSAILGLVALIFEYEPSFLDFNLPAIFIEDLNLFSDKRLFGIVNNNILNEILGILTIISSLFVAFSKEKLEDEYISKIRLESLVWAVYVNYGVLLFAFLFIFDFTFLWVMLFNMFTVLLFFIIRFNWQISKLKKSAHHEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHD2</accession>
    <name>A0A5C6ZHD2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">OmpA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_08365</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006664">
        <property type="entry name" value="OMP_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01021">
        <property type="entry name" value="OMPADOMAIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023023200" evidence="3">
        <location>
            <begin position="21"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="domain" description="OmpA-like" evidence="4">
        <location>
            <begin position="514"/>
            <end position="633"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD89393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="638" mass="71389" checksum="A413A681994E6E31" modified="2019-11-13" version="1">MKKIITLITIAALSSFSLIAQDANTKKADKHFNRFEFVDAAEDYQEIVDDGNANAYVYSQLAESYYNFFKTIEAEMYYAKALETSSEPEMVIKYSQMLKANGKYEESNVQMRKFAQMRPSDERAIAFIENPNYLPKILEKGKKFNIQNASFNTEYSDFGGTLQDGKLYITSARNTSRKTYGWNQQPFLDMYQLTKNTDGTFQEATLVEDKINTKYHEGLVSFSPDGNTMYFSRESYFEKEFEKDSTSNVKYGTLQLFTAKKDGNNWNNVQGFEMNNNNYSVKNPAVSPDGKTLYFASDMPGGFGLFDIYKASINDDGTLGEAVNLGQKVNTPGREMFPYVSSNQTLYFSSNGHLGLGGLDVFYTREIDGRMAPIRNVGIPISGNSDDFAFYLDEESGEGFVSSNREGGVGSDDVYLIKKLQPLCDVLITATITDDTTGDPIQGASVALSDKDGNQLLTKQTNAEGKVEFIVECDQESELQISMVDYDSKKVIVEASEEEEVEVSIQLEPIERLISAGSINLETIYFDFDKSNITSKAAFELDQLVQIMNKYPNLVIKATSHTDSRGSDTYNEDLSERRAKTTVQYVISKGIDASRISGIGKGETEPKVDCSAGCTKEQYQMNRRSEFIIVSGAAQEQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHL2</accession>
    <name>A0A5C6ZHL2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF1624 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_11080</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012429">
        <property type="entry name" value="HGSNAT_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07786">
        <property type="entry name" value="HGSNAT_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="185"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="214"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="254"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="294"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="324"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="HGSNAT_cat" evidence="2">
        <location>
            <begin position="5"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="364" mass="41852" checksum="8863183B3C0141CA" modified="2019-11-13" version="1">MKSDRLFFIDAVRAFAILMMLQGHFIDTLLNPIYRDESNMAYLVWSYFRGITAPTFFTISGLVFLYLLLKAKAAQKDKKRIKKGIYRGLLLIAIGYTLRADVFGWFQGKFQDYVLVVDVLQCIGLSLILLIGCYALLRNQLMILSVMLLSLGILSFLTEPLYRGLDLTFIPKVFANYMTKANGSIFTILPWFGFTALGGFLATVFFAQVHKPRFRLFTVILFFALGLFLIHYSSWCLMQVYRWSDVQVFKDVAYYNYLFTRFGNVLVLFGVFYAAEPLLKQSIISKIGQKTLSIYVIHFVIIFGSFTGLGLKHFFSESLTPTEAIVGAILFMFLVCLISFHYVKTNAFLYKSVRQLIKRIRTKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHW2</accession>
    <name>A0A5C6ZHW2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08075</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023080940" evidence="1">
        <location>
            <begin position="25"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="68" mass="7662" checksum="76655E59A53737A2" modified="2019-11-13" version="1">MKKTASARCVGFLFAVVLQLRNSAANPFNSFRKQPSVLELFSINEKNSICKMRRFFICSSVAASEQRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIE1</accession>
    <name>A0A5C6ZIE1_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">UDP-glucuronate decarboxylase</fullName>
            <ecNumber evidence="4">4.1.1.35</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_09860</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Nucleotide-sugar biosynthesis; UDP-alpha-D-xylose biosynthesis; UDP-alpha-D-xylose from UDP-alpha-D-glucuronate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.35" evidence="4"/>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00796">
        <property type="reaction ID" value="UER00771"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048040">
        <property type="term" value="F:UDP-glucuronate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042732">
        <property type="term" value="P:D-xylose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033320">
        <property type="term" value="P:UDP-D-xylose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044516">
        <property type="entry name" value="UXS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43078">
        <property type="entry name" value="PTHR43078"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="7">
        <location>
            <begin position="5"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD89071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="313" mass="35514" checksum="4B87EC80D3BC4D7D" modified="2019-11-13" version="1">MKRILITGGAGFVGSHLCERLLNEGNEVICLDNYFTGSKKNIEHLMDNKYFELVRHDVINPYMIEVDEIYNMACPASPVHYQYNPIKTIKTSVMGAINMLGLAKRVNAKILQASTSEVYGDPAVHPQPETYWGNVNPIGLRSCYDEGKRCAETLFMDYHIQNDVKIKIIRIFNTYGPNMNPHDGRVVSNFIVQALEGKDITIFGDGNQTRSFQYVDDLVEGSIRMMNSRDGFVGPVNIGNPTEFTMLELAEKIIELTNSKSKLVYMPLPQDDPLQRQPVIDLAKKELNGWEPKVQLDEGLRKTITYFDELLQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIS3</accession>
    <name>A0A5C6ZIS3_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6 7">Protein RecA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 7">Recombinase A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 11" type="primary">recA</name>
        <name evidence="11" type="ORF">ESY86_07625</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 8">Belongs to the RecA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00983">
        <property type="entry name" value="recA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00268">
        <property type="entry name" value="RecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013765">
        <property type="entry name" value="DNA_recomb/repair_RecA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020584">
        <property type="entry name" value="DNA_recomb/repair_RecA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023400">
        <property type="entry name" value="RecA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020587">
        <property type="entry name" value="RecA_monomer-monomer_interface"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45900">
        <property type="entry name" value="PTHR45900"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00154">
        <property type="entry name" value="RecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00142">
        <property type="entry name" value="RECA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54752">
        <property type="entry name" value="SSF54752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02012">
        <property type="entry name" value="tigrfam_recA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00321">
        <property type="entry name" value="RECA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50163">
        <property type="entry name" value="RECA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 8" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6 7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 6 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 6 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="RECA_2" evidence="9">
        <location>
            <begin position="38"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="RECA_3" evidence="10">
        <location>
            <begin position="202"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="68"/>
            <end position="75"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD89646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="334" mass="36021" checksum="940C9210BE20A2F1" modified="2019-11-13" version="1">MSSEKDAKLKALQLTLDKLDKAYGKGTVMKMSDQAVVDVEAISSGSLGLDIALGVGGYPRGRVIEIYGPESSGKTTLTLHAIAEAQKAGGIAAFIDAEHAFDRTYAQKLGVDIDNLIISQPDNGEQALEITDNLIRSGAIDIVVIDSVAALTPKAEIEGEMGDSKMGLHARLMSQALRKLTGSISKTKCTVIFINQLREKIGVMFGNPETTTGGNALKFYASVRLDIRRSTQIKETDGSVMGNKTRVKVVKNKVAPPFKMAEFDIMYGLGISKVGEILDVAVEQEIIKKSGSWFSYGETKLGQGRDAVKALIKDNPELMDELEAKVREAVKPEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIS9</accession>
    <name>A0A5C6ZIS9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08595</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="163" mass="18480" checksum="47BAFB8388FB6232" modified="2019-11-13" version="1">MRNSNLPADPTAMILGVIALILSLVGCCCGLFAFIPLILSIIGLVMAHKSLQTYRYNSELYNPQSRSNVYTAKILNIIALIISAGMTLVYVAYFAIYGVVFSEIIKEAYEHRNENGDFQFEWENDSLNEDYNRDLERDSIYMDSIIIDETEMLDDNEAIDTLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIZ8</accession>
    <name>A0A5C6ZIZ8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-grasp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_10285</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Might have a role in establishing the nucleoid structure of elementary bodies.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the histone H1/H5 family. HCT subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030261">
        <property type="term" value="P:chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009970">
        <property type="entry name" value="HC2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07382">
        <property type="entry name" value="HC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="5">
        <location>
            <begin position="96"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="321"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="321"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD89145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="446" mass="50194" checksum="F326738BDFCA36F1" modified="2019-11-13" version="1">MRKIGILFGQENTFPQAFIDRVNQRIKDENIKDMMAEAVSIETVEQAKSDEYAVIIDRISQDVPFYRAYLKNAAITGTAVINNPFWWSADEKFFNNALAEKIGVPVPKTFILPSSHRPPDTNENSFRNMKFPFNWEKMFDTIGFPAYMKPHDGGGWKSVYRVENPDDLWKKHGETENLVMMLQEEIDFKEYFRCYVLGTNKVHIMQYEPRNEHHLRYVIDGPKVDQKILDTVHDYCIKLNQALGYDFNTVEFAVRDGIPYAIDFCNPAPDADIHSVGQDNFDWIVENAATMAIEKAKQYKKGQMNLTWGSFVTDQVGSKKAAAKEAKPKKAETKKPVAKKTTDKKPSAKKATAKGDDKKTALKKVAAKKPVLKASEAKKAETKKPVAKKTTDKKPSAKKATAKGDDKKTALKKVAAKKPVLKASEAKKPAIKKAPAKSAAAKTKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ20</accession>
    <name>A0A5C6ZJ20_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_09660</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="126" mass="14847" checksum="D9EEC7686B6CAE67" modified="2019-11-13" version="1">MDSFIGIRFKKETAKRFQQFSRTHFKSHTVAMSTMLDFFFYNEISPKEKLGPTGRTIEASIKKRINAVIAIMRDMEKTQTKPTVAMIESLFQTEAPTKKPLILEKKYVDEKKEVRFREKENHNNEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ65</accession>
    <name>A0A5C6ZJ65_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aminopeptidase P family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_12085</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023129221" evidence="1">
        <location>
            <begin position="18"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M24" evidence="2">
        <location>
            <begin position="198"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="445" mass="51027" checksum="E40E865FD7F2737A" modified="2019-11-13" version="1">MKLICLLFLSLSFQLNAQQILSVEKQAQVIDEILADRFNNVLPELMDRAALDMWILISREYNEDPVLKTMLPAKWLNARRRTIIVFYRDSAKNTIEKLAVARYDFGDNIKSAWDKEQEPNQWKRLVAIIEERNPERIGLNYSKHFNIADGLDKTDFDEFMEILPKQLKPKVVSAEKLAVAWIETRTEREMVIYNQLVAITHDIIAEAFSEKVITAGITTTSDVEWWMRQKVSDLGLETWFHPTVDVQRTQNELQGHLYSFSDRPEQQIIMPGDLIHCDFGITYLRLNTDCQELAYVLKPNETKPPQFLTDALAEGNRLQDIFTANFETGKTGNDILLKSLSTAKEEGLKPSIYTHPLGSYGHSAGPTIGMWDSQQGVEGAGDYPLYPNTVYAIELNTTVNIPEWKRDIRIMLEEAGFYGTDGFRYVNGRQTKLLTIPRVKEQLGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJA7</accession>
    <name>A0A5C6ZJA7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">T9SS type B sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_08370</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026341">
        <property type="entry name" value="Bac_Flav_CTERM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="SSF49265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04131">
        <property type="entry name" value="Bac_Flav_CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022879320" evidence="1">
        <location>
            <begin position="19"/>
            <end position="1639"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="2">
        <location>
            <begin position="181"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1639" mass="175335" checksum="6A37546903155220" modified="2019-11-13" version="1">MKKVTLLLMFCSIFGMQAQIYLQENFDTAIPATWTVTDEGGATGDSWISGKQAGTNSFDGTNAALVNSDANGADTHLIETLTSPVFDASDASALFLDFKQYYLNIGPDFSKVEIFDGTNWIEVLNQTATVGSFATPNEQHIDITQYANANMQVRFIYDDGDVWAWYWMVDDVLVYNSTCNFPSALSVASITETTADLSWTPGGVETAWELINQEADGPVPTEGDTGTATSNNPYTVSGLTLGTNYEFYVRANCGAEDGNSNWAGPFAYRVSGVGEVCGNPILIDTALPYTTTDSTSDYGDDYSGSPGEACGSGFGYLNGDDVVYSYTPAADTSIDITLSALNSNYAGIFVYTDCANIGTQCDAGAVNGFASGNLVIDNYAVTNGQTYYIVISTWAAPQSTDYTLTLTENTCVDPQATFSVLSDCDNAPQFFIEADLTSLGSASAVTISDDQGSDAQTVSALGIVSFGPFPNNTPVEITIANNDDANCVITSTGLTQQYCLDTIVDCTAGPINAFYCYQNSDTNQFSYTSTDGSSLRLTINSGEVEGAPWDFLVILDSDGVTQLYNGEGNDGDISGLVFQSSGDTIYFQITSDTSVSCESGSFSEGIDYTVVCATCVNPTATYNVVSDCVNGPQFFVDVDITDLGSASALTVTDNQSSDPQPVTETGTVTFGPFANNTPVEITISNDDDNNCTIESNSLTQEFCFDTLIDCSAGPYTVSYCYIANDTNQFSYTSNDGTPLNLTINSGEVEGDPFDFLIILDSDGVTELYNGEGNNGDLAGLTFQSTGDTIYFQIESDFSVSCESGTFDEGINYTVSCATCINPAATYQIVDDCDNGEQFLIDVNLSTIGDASSVTISNNVNADTTTATEAGIYQIGPFPFLTDVIVTLSNDQDVNCVVNSSAFQLSACPPENDNPCNATTVAVNDDASCTLFASGTLLEATPSGIASGSCAGNPNDDVWFQFTASSEFQIVQMLNIDSTGFFENIDHAVYSGSCEAPVELYCSAGEASITPELTVGDTYFVRVFSAGNLPTDYTFDLCIKPGTGNVTVDQEEYTVEQLVTDVLINSPCAQVTNITFSTGTNFGSTNGIGYFEAEEGSFPFTEGLVLTTGNASRAAGPNFDNLSDGFEGDWVGDADLDAIVADETFNATIVEFDFVPLSNEISFDFIMASEEYDQGFFECEYSDAFAFFLTDEDGNTTNLAVLPGTNTPILVTNIHPDNGSCPAVNEEYFGEYIPTGLPPISFDGRTAVFTAFSEVNLGETYHIKLVIADARDTAFDSGVFLKAGSFDIGEIDLGADITVEAGTATCNGAPVTIQTTAVNVNHVWYKDGFEIVGETSNVLTVTEEGTYTVQIIFSAQCNVSDEIVIEYLPLPQIAETPPSLVGCSIGAGTAVFTLEDNNTEILAGVDDNSNYTISYHLSEEAATNGDNALQSPYTSVSNPQTVYALVTNNTTGCEETTSFDLILGIEPETTFTEDFDYEVCPDAVNPIIITATAVNYELSNVNIQWYRDGQPEPIAGQSGLTLPVLEGDIYTIVVTFNDTGCSASQDIEVITLESCVIPQGISPNNDGKNDRFDLSNFRVTSLEIFNRYGSSVYEKTGSYVDEWFGQAENGDELPVGTYFYSIQFEDGERVTGWVYIQREN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJU3</accession>
    <name>A0A5C6ZJU3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_04150</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="398"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="160"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="468"/>
            <end position="682"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="685" mass="77655" checksum="EB8D7EF8EF852A17" modified="2019-11-13" version="1">MKQLLTLAVLCATLFGFSQTDNIDSLTVQLAYQKQDSAKVETSLLLVNALYHNADYKKALLYIDKTERLANLLNHSKGVADANYYKALIYSDKNDYYNAIDGFNKSLKIYLQLGDTIGIAKVNNSIGIIEIKRGNYSVGLENSLSAIKIFEDKNLKTELSSAYNSLAEAYYRTHQTDKALEYNIKALRVRQDLLDSLGIKLSTKNIAMLYSERKEHRRAIEYYEDVLGLLNAAEDDTLKGEILPRIGVEYLEFKNYEKAGNYLAEGLKFNRNIKNSDGIVRSLNAMGSLNMQQGKTRLARIQINEAHDLAERITDKSQLLTNYRLQKEWDSINKNFQNAFFWQGKYYTLKTALDKENTPILPTITEDSQPDLLEDINYFKALAEKKEALNTNKETDGALLIVIAVLSVLLLIVGTMFLLYYIERRKKSQKHSVSTQPDASLVSQNKVYADKIKNLEEVNKVKDRLFSIVSHDLKDSISSIKAFIDLLKDDNLSREEFQDLIPELSENADSASDLLFNLLNWSKSQMQNLKPKPEIFNIQDVFHNKMSLVEQKVEQKRIAFIDESHRDFIYADKSMVEIVIQNLITNAVKFTSVGDVITISNTDHQGKSLICVEDTGVGISNENLSKIFLNSNFTTTGTNNEKGNGLGLTICKELVELNGGRIWVESKLNVGTKFYVELPKMKPVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJW4</accession>
    <name>A0A5C6ZJW4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">HAMP domain-containing histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_08575</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="182"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="384" mass="44195" checksum="B2D31CF16115A48B" modified="2019-11-13" version="1">MSIRINRNITRWLIIISSFFIITLILWNTYMFFQNFKEEERTKMQNWSFANETLIATTNDDEIKMTSRILESNTTTPMILVNADDEITSFRNIDTLRMRVPKLALEKLKSTFENENKPIPVYIEDELYSTIYYGNSPLLNKLKYYPLALLLIIFLFAAVAYFFYKSSKTADQNKLWTGMAKETAHQIGTPLSSLVGWTEILRSENVDPDYLIEIEKDISRLQTITDRFSKIGSVPTLKQADIVHETIETFDYLKARFSKLIEFNLVAPQEEILVALNKQLYSWTIENLVKNAIDAMKGKGTLHLTMTQDDSYVKIKVSDTGKGIPKSHFKTVFRPGYTSKKRGWGLGLSLAKRIIEDYHKGKIKVLSSELGKGTTMQISLKKVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJX2</accession>
    <name>A0A5C6ZJX2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CYTH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033469">
        <property type="entry name" value="CYTH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023577">
        <property type="entry name" value="CYTH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012042">
        <property type="entry name" value="NeuTTM/CthTTM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40114">
        <property type="entry name" value="PTHR40114"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01928">
        <property type="entry name" value="CYTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016487">
        <property type="entry name" value="CYTH_UCP016487"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01118">
        <property type="entry name" value="CYTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55154">
        <property type="entry name" value="SSF55154"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51707">
        <property type="entry name" value="CYTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CYTH" evidence="1">
        <location>
            <begin position="3"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="158" mass="18433" checksum="2AD31BF9DDA68656" modified="2019-11-13" version="1">MNTTEIERKFLVRSEDFKTEAHKYTRIIQGFLNTHPERTVRVRLKGDLGYLTVKGKSNDSGLSRYEWEREISKTEAEALLKLCEAGSIDKTRYEVQKGTHVFEIDVFHQSNEGLVVAEVELGHEEESFEKPIWLGEEVTGDKRYYNSQLAKHPFKHWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK70</accession>
    <name>A0A5C6ZK70_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF2141 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_07130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018673">
        <property type="entry name" value="DUF2141"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09912">
        <property type="entry name" value="DUF2141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="172" mass="18956" checksum="604CACF038820E61" modified="2019-11-13" version="1">MMNNILFKVFFQNTEHSEKPQIFRKFSQLLFCLAISLVWLPSSGFAQTECPAIHVKIQNISNNTGVIACAIFETGEGFPNKFLQFAPKIMITQISGTDASFEFSDILPGKYAIAVIHDKNRNGELDTNFLGIPTEGYGFSSGAEVTLSAPSFSDAEFIYDGGNLQMSISLSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKF1</accession>
    <name>A0A5C6ZKF1_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Isocitrate lyase</fullName>
            <ecNumber evidence="1">4.1.3.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Isocitrase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Isocitratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_03670</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>D-threo-isocitrate = glyoxylate + succinate</text>
            <dbReference type="Rhea" id="RHEA:13245"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
            <dbReference type="EC" id="4.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6">Can also use Mn(2+) ion.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.1" evidence="1"/>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004451">
        <property type="term" value="F:isocitrate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00377">
        <property type="entry name" value="ICL_PEPM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039556">
        <property type="entry name" value="ICL/PEPM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006254">
        <property type="entry name" value="Isocitrate_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21631">
        <property type="entry name" value="PTHR21631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00463">
        <property type="entry name" value="ICL"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001362">
        <property type="entry name" value="Isocit_lyase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="218"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00031022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00031921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001362-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001362-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD90476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="541" mass="60487" checksum="9284EC0F36B283E5" modified="2019-11-13" version="1">MKNFAQSKYSSALETVRDLKARYGTTWDAINPESAAKMLTQNRFKTGLDIAKYTADIMRKDMAEYDADSSKYTQSLGCWHGFVAQQKMIAVKKHHKTTSKKYLYLSGWMVAALRSEFGPLPDQSMHEKTAVPALIKEIYDFLRQADAIALNDLFHRLEKGEDVQDQIDGFETHIVPIIADIDAGFGNEEATYLLTKKMIEAGACAIQIENQVSDAKQCGHQDGKVTVPHEDFIAKLNAVRYAFLELGVDDGIIVARTDSEGAGLTQKLPVSQEPGDLASKYLGFVEAEAIAIADAKEDDVLLKRDGKLVRPVRLANGLYKFKDGSNIDRVVLDCITSLQNGADLLWIETPTPSVTQIAHMVNRIKEVVPNAKLVYNNSPSFNWTLNFRNQVFEEMMAEGENMTAYDRNNLMDAHYDGSELCHRADQKIKTFQVDSAREAGIFHHLITLPTYHTTALHMNDLTEGYFGNEGMLAYVKGVQRQEIRKNVSCVKHQRMAGSDLGDDHKTFFAGDKALKSGGKNNTSNQFEIKKNAPKLELVLDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKF7</accession>
    <name>A0A5C6ZKF7_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Recep_L_domain domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000494">
        <property type="entry name" value="Rcpt_L-dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01030">
        <property type="entry name" value="Recep_L_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Recep_L_domain" evidence="1">
        <location>
            <begin position="58"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="557" mass="61585" checksum="9A4FE526B416B0E0" modified="2019-11-13" version="1">MNYCIKNNYFFIIILSIFSCTTDDDNLEESLRLNSIEGNFLLETQQDVNDFGDLNYESIDGSLVIGNSTGMSNITSLEPINNLKAVFGFLSIQNNPQLTSLSGLENLRYMCHSEPSSIRIINNDGLTEISAISNINYCDMMSLTLKDNNSLSNIDAFSEIRNLSQIILQSNENLIDLSAFNNLEQVRYLALIDGNFSNVGFNNLNTCDTLHIVSCNNLTHVNSLSNLTNLRVLELGLPGAFLQYQYDPILSNQSLASLDGLSNVTNLEAIGIGGGSSDLRSLPNFKGTIGSIALHNTAIENLDGFSQGTQDYHTDLYIYDNYNLENVDGLLNYHVLGEIYLVNNTNLNNIDGFDTVSEIIAGYIFIDGNSIEQTNSVFENLTTINFYEINITNNSGFDHFSGFNVLNTENLSVNINNNTDLASIDAFNTLERVSLNFINNPNLTSILGFDNVIEADLTIGYSAISNPNQPVEIIDVFNPSAIINNLGIFNTNISNLDSFQNFSLNELIQIYNNGLLTDFCGISNQVVNSTTSTLIYDVRDNLFNPSRYDLVDGDCSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKI7</accession>
    <name>A0A5C6ZKI7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">OsmC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_04985</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003718">
        <property type="entry name" value="OsmC/Ohr_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036102">
        <property type="entry name" value="OsmC/Ohrsf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02566">
        <property type="entry name" value="OsmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82784">
        <property type="entry name" value="SSF82784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="152" mass="16997" checksum="A3D5AAB56F40D3C5" modified="2019-11-13" version="1">MDKHSYNVDISWTEARKGMMCSPELEHKDTQETNCIEVATPPEFPGGMPHIWSPEHLFTAAVASCLMTTFLAIAENSKIEFVSFKCGSKGILENVDGKFVISEVLLFPEVVITDESQRERVERVIEKSEKACLISNSITSKITMDIKVSVQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKI8</accession>
    <name>A0A5C6ZKI8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Alpha/beta hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_03210</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="222" mass="25856" checksum="43F09E68C3201068" modified="2019-11-13" version="1">MEPGIIHVYLMPGMAANPRIFEFIKLPKDQFEMHWLEWMLPDKNETLQSYAKRMINKIEHHNVVLLGVSFGGILVQEMSKHMQLRKLFVVSSVKSKHELPKRMKLMKFTKAYKILPTQLVGNIDLLAKYAFGETITKRIELYKKYLSVSDKHYLDWAIEHVIEWEQDAPNEDAIYIHGDKDIIFPNSCGGKCIVVKGGTHIMVITKFKWFNENLPKLILQDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKQ8</accession>
    <name>A0A5C6ZKQ8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03390</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PlsC" evidence="1">
        <location>
            <begin position="32"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="182" mass="21078" checksum="5B78F4A53A600DB9" modified="2019-11-13" version="1">MRWLAKLVYFKLLGWTVTGNLNFSKDTVKKAVIIALPHTSWHDFYIGLLLRKVTGVKTNFVGKKELFHWPFGYYFRAIGGAALDRTSGQNKVEAIAKLFESKEEFRLTLAPEGTRKKVTEWRTGFYYIAKAANVPIIMFTLDFKNKENHISEPFHPTHDRAADFKFMKAFYQGVEGKKPEYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKR0</accession>
    <name>A0A5C6ZKR0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Serine hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_02380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase" evidence="1">
        <location>
            <begin position="184"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="489" mass="56354" checksum="CD221BEE25917360" modified="2019-11-13" version="1">MEIQTIRKNNFKKTFPLLLMIVILAFGCSSPKEKSDYEKLLEYEGNYEYEYVDKTTLDIVASELDTTLYAIVDNAKYPLKHIALDSFTNIQDVPVVFERDKTNRVKGYRTDGLEFKLITSEIEKTEMFPRKELFHNPDSYVYHKPKKTEDGLETGSLEDEFKNPEPIIDMVKETIKGKFPDVHSILIYKNNKLVLEEYFYGYDENIPHQLRSATKPFIGGILGIAIDQGFIKSEKDKLLPYFNSTYSEIANLDDRKKEITIENFLMYRHGMDCENDNPKSKGNEQAMMASKDWVKYTLDLPMVKESGKSSSYCTGCALTLGSLVEMATSKNIEDFAKENLFNPLGVSNYDWTFEPNQASMTTFSQMYLTPRDLIKLAKLFKDGGKWKDKQIISESWINKTFDMDEGDYGYLWEHKYFVIDGQKYNSYLASGNGGQKINIWPELDMITVFTGGNYNSYALYGKSTPPNEMIPNYILKTGEKPADNNVYKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKU5</accession>
    <name>A0A5C6ZKU5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="61" mass="6716" checksum="4C1C95F7BA38DB81" modified="2019-11-13" version="1">MGFYKKIGLANLLILVLCAVIIIVAEYLFLTGDQLHGIFIGLWAPTILGIVIFINQITNGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKV5</accession>
    <name>A0A5C6ZKV5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_05775</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="96" mass="10723" checksum="DB7B80AAB93C7180" modified="2019-11-13" version="1">MKQISVESQSQFAVFRPSVFRLPSSVFCLLSPVSRLPSSVLRLPSSVFRPPSSASVFCLRLLSPVFCLPSSVFRLPSSIFRLLSSVFPISFQNLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL15</accession>
    <name>A0A5C6ZL15_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">3'-5' exonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Exonuclease_RNaseT/DNA_pol3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exonuclease" evidence="1">
        <location>
            <begin position="8"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="258" mass="29511" checksum="44629A19B3F74943" modified="2019-11-13" version="1">MQLNLTKPICFFDLETTGINISKDRIVEIAILKVHPNGKEERYTQRVNPEMPIPAEVTLVHGISDADVADMPTFLEISKEVHTMIKDSDLGGYNSNRFDIPLLAEELLRADVDFDMKNKVSIDVQTIFHKMEQRTLSAAYKFYCDKNLDNAHSAEADTVATYEVLKSQLDRYDELENDANFLADFSSRKKFADFAGFIIYNKKDEECFAFGKHKGKLVTDVLDKEPGYFGWLLNADFPRYTKKVLTAIKLRAFNNKLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL34</accession>
    <name>A0A5C6ZL34_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 8">Methionyl-tRNA formyltransferase</fullName>
            <ecNumber evidence="4 8">2.1.2.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">fmt</name>
        <name evidence="11" type="ORF">ESY86_06710</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 8">Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>(6S)-10-formyltetrahydrofolate + L-methionyl-tRNA(fMet) = (6S)-5,6,7,8-tetrahydrofolate + H(+) + N-formyl-L-methionyl-tRNA(fMet)</text>
            <dbReference type="Rhea" id="RHEA:24380"/>
            <dbReference type="Rhea" id="RHEA-COMP:9952"/>
            <dbReference type="Rhea" id="RHEA-COMP:9953"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:78530"/>
            <dbReference type="ChEBI" id="CHEBI:78844"/>
            <dbReference type="EC" id="2.1.2.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the Fmt family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.9" evidence="4 8"/>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004479">
        <property type="term" value="F:methionyl-tRNA formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd08646">
        <property type="entry name" value="FMT_core_Met-tRNA-FMT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08704">
        <property type="entry name" value="Met_tRNA_FMT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00182">
        <property type="entry name" value="Formyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005794">
        <property type="entry name" value="Fmt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005793">
        <property type="entry name" value="Formyl_trans_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002376">
        <property type="entry name" value="Formyl_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036477">
        <property type="entry name" value="Formyl_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011034">
        <property type="entry name" value="Formyl_transferase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044135">
        <property type="entry name" value="Met-tRNA-FMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041711">
        <property type="entry name" value="Met-tRNA-FMT_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02911">
        <property type="entry name" value="Formyl_trans_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00551">
        <property type="entry name" value="Formyl_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50486">
        <property type="entry name" value="SSF50486"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53328">
        <property type="entry name" value="SSF53328"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00460">
        <property type="entry name" value="fmt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Formyl_trans_N" evidence="9">
        <location>
            <begin position="7"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="Formyl_trans_C" evidence="10">
        <location>
            <begin position="208"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Tetrahydrofolate (THF) binding" evidence="8">
        <location>
            <begin position="113"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD89888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="317" mass="35435" checksum="B1AD6B2DBCBF887F" modified="2019-11-13" version="1">MKTDALRIVFMGTPDFAVANLKALVEAKHEVVGVITAPDKPAGRGRKLQQSAVKTYAQSQGLKLLQPTNLKDEAFLSELKALHANLQVIVAFRMLPKAVWDMPKYGTFNLHASLLPQYRGAAPIHWAIINGETKTGVSTFFIDDKIDTGAIIAQTEIGIEPTETVGQLHDRLMHLGSHLVLETVDKIAQGEVKTYIQPENEDLKTAYKLNKDNCKIDWTKDVATVYDKIRGLNPFPSAWSFLENGEEQQSVKFFDITKEAVSHKYDFGKIINSKTALKVAVKNGFIHIKELQLPGKRKMDINSLLNGYEFEENAKML</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLD4</accession>
    <name>A0A5C6ZLD4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_04425</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045738">
        <property type="entry name" value="DUF6088"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19570">
        <property type="entry name" value="DUF6088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="202" mass="22539" checksum="A1679910C0EC225C" modified="2019-11-13" version="1">MISIEDKIKRKIISQKDGTLLFPEDFNDIGSSEAVRLALHRLFKDSFITRIAQGIYVRPKNNSLIGGILPTAEEVAYGIAQRDRIKIVPTGIYALHALGISQQIPLKLTFLTDGAPREIQIGKQAIKLKRTTPKNLKAIGKISSLVIQALRSIGKGKVTHDEELKILELLQEESETNLKHDIKLAPVWIKKTMSKALNNDKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLG9</accession>
    <name>A0A5C6ZLG9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CPBP family intramembrane metalloprotease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06405</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="208" mass="24337" checksum="CD184A3B5A417F8B" modified="2019-11-13" version="1">MQSYVYKISELFIIFIFIPVSFAIDYAIWLKMTIGTIGFLYVLFVLMRVEKIKFEIAAQINWRSFLQRTFSQLVIIAVLTTLYMWFVDRQNLYMVVLNKPLLWLAILFFYSLFSVYPQELIYRTLFFKRYQSLVKNEMGFILLNAALFSLAHLFFGNVLVMVLTFVGGLLFALTYKKTKSTLLVSLEHAIYGCWLFTVGMGDMLGFPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLK8</accession>
    <name>A0A5C6ZLK8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_02945</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="3"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="125" mass="13892" checksum="2086C1824E23AF85" modified="2019-11-13" version="1">MNKVLLVEDDLNLGIMIHDLLELSGYEVKLLRLADQTIKCLQQDQFDLVIMDKLLNGMDGTVICSEIRKTDTISDTPVPMMSALDGAKTLCIKAGATNFISKPFEIEDLLAKVKDVIRHETDIGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLL6</accession>
    <name>A0A5C6ZLL6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_07195</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="116" mass="13732" checksum="4683B87A3CD0FF00" modified="2019-11-13" version="1">MQKQCPECGDKIVGRIDKKFCSDACRNSYNNTINKDHRNIIRNTNNRLRKNYRILETLNPEQKTKCSKAKLIEQGFDFNYFTSIYTTKVGTVYYFVYDQGYLPLEADYYALVKRES</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLM8</accession>
    <name>A0A5C6ZLM8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF3368 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_02150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021799">
        <property type="entry name" value="DUF3368"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11848">
        <property type="entry name" value="DUF3368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="164" mass="18997" checksum="28799679E24DA72D" modified="2019-11-13" version="1">MKNGLVILDSGPIFSLASVNRLEMLDSLFDKAVIPKAVWQEITFHQTTESYEIIERFLEKRVVEIEGFNELSFIMDYGDSEALILYRQLKADFLLIDDKKARSIAENSKINCIGTLGILIPARRRNFIKDLRPIFKGFLENKRYYSIGLLNEVLKTFDEELLND</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLN2</accession>
    <name>A0A5C6ZLN2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_01065</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="172" mass="19666" checksum="3CBFBDBC38C11C76" modified="2019-11-13" version="1">MILKAFKEKSNQKYINRLLNAASNRDKHAIVKSVGVVLNVDEFTDVEVFNRFFKELGLQEANTKIVSFAKDPKTSNELWGAYFNAKHIGWNGKIKHPDLQHFVNTAYDVLICFYNSKHVELDVIATSSKAHFKVGISSSDPRLYDLIIGVETSQFPIFKQELIKYLTVLNKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLV7</accession>
    <name>A0A5C6ZLV7_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Threonine synthase</fullName>
            <ecNumber evidence="5">4.2.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">thrC</name>
        <name evidence="12" type="ORF">ESY86_01495</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + O-phospho-L-homoserine = L-threonine + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10840"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57590"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="EC" id="4.2.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 9">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the threonine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.1" evidence="5"/>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004795">
        <property type="term" value="F:threonine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000634">
        <property type="entry name" value="Ser/Thr_deHydtase_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029144">
        <property type="entry name" value="Thr_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037158">
        <property type="entry name" value="Thr_synth_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004450">
        <property type="entry name" value="Thr_synthase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14821">
        <property type="entry name" value="Thr_synth_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00260">
        <property type="entry name" value="thrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00165">
        <property type="entry name" value="DEHYDRATASE_SER_THR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0456">Lyase</keyword>
    <keyword evidence="8 9" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0791">Threonine biosynthesis</keyword>
    <feature type="domain" description="Thr_synth_N" evidence="11">
        <location>
            <begin position="2"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="PALP" evidence="10">
        <location>
            <begin position="98"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="9">
        <location>
            <position position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR604450-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF14821"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TXD91284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="435" mass="48711" checksum="0381DE8960777333" modified="2019-11-13" version="1">MNYYSLNKKAPHTSFKNAVVKGLAPDRGLYFPEHIPALPASFFETIDDKSYSEIAFEAIKQFVTPDIPEPILKTIIEETLSFEFPIVRLNEHISTLELFHGPTMAFKDVGARFMARCLGYFNRNNTEEVTVLVATSGDTGGAVANGFLGVKGVHVVILYPSGKVSNIQEKQLTTLGQNITALEVDGVFDDCQDMVKQAFLDPELTDKMQLTSANSINVARWLPQLFYFMFAYKQLHKKHEDLVFSIPSGNFGNICAGMMAQQLGLPIKHFIASNNANNVVTEYLTTQLYNPKPSVATVSNAMDVGNPSNFIRIQEIYKNDFEELKRNLSSYSYSDDATKAALLEIYKQFNYIADPHGAVGYLGCKDYLKDHPDAHCVFLETAHPTKFLDTVEAVIDKKVDLPAQIKAVIDKKKIATKISSYEDLKRFLLAEQKQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLZ1</accession>
    <name>A0A5C6ZLZ1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_07900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="249" mass="27781" checksum="FC0F6678A55E8403" modified="2019-11-13" version="1">MKKILTGIITFFCPSFLMRFLLRCMGHKIGKNVKVGFSFLVIKKIELGDHVRIGHFNLFLNDRITLQSNVIIGYLNIFKGPFGLILSEKAAIGNKNYLTRARLGITYGESNLSLGELTKVTTGHHLDLTRSIRFGDFSILAGIRSQLWTHGYYHADQGKDRVRIDGQINIGHNVYIGSGCIFNPGVNVANAVHIGGGSVISKDLDQPGMYVGQGLRYLENNLETIKLKLDRIEDSDLIEEVYSKKANPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM16</accession>
    <name>A0A5C6ZM16_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Insulinase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_00610</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the peptidase M16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001431">
        <property type="entry name" value="Pept_M16_Zn_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="SSF63411"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00143">
        <property type="entry name" value="INSULINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023123424" evidence="3">
        <location>
            <begin position="26"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16" evidence="4">
        <location>
            <begin position="65"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_C" evidence="5">
        <location>
            <begin position="219"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_C" evidence="5">
        <location>
            <begin position="710"/>
            <end position="880"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD91126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="948" mass="108146" checksum="55D5EFCA217B63F4" modified="2019-11-13" version="1">MIRKSKQLQRLAFALCFVLTSSVFAQETLSKKASTNLSEEKIPFNPEVKMGKLDNGLTYYIKNNGKPENKVELRLVVNAGSILENDEQRGLAHFMEHMNFNGTKNFEKNELVDYLQSIGVKFGAHLNAYTSFDETVYILPIPSDDPEKLEKGFQIIEDWAHNALLTDEQIESERGVVLEEYRLGQGANERMMQEYLPKMLYGSKYADRLPIGQKEVLENFDYDTLRQFYKDWYRPDLMAVIAVGDVDVATLEAKIKEHFGNIPKPNNPKPRESFELPNHKETLVSVESDKEASFSQVQVMFKDTEDAQPDTTLEDYRKSIVENVFSQMINNRLDELTNGENPPFVFGSSYYGGTYAKTKNAYQSFAMTSETGQLKALQTLLEENQRVKQHGFYEGEFERAKKDIMARMEKSFKDRDKMESNRIVGEYIRNFLENEPMPGIEWEYNFYKEQLPKIDLTEVNALISDYIKDENRVIILTGPEKEGLTNATEAEVRSILEEVGEEELAPYEDTEVASSLITDVPKAGTVTDYKTNDVLGTTTLTLSNGAKVTYKVTDFKNDEILFDAYSYGGNSLYSLEDYKATANANGGLSEAGVNGFDKTEMGKMMSGKIVNVRPRISTYSEDISGNASPKDLEDLFQLVHLYFTALNKDEKAYNSYIDKQKSFLGNMMSNPQTYFSIKMGEWMYGDNPRYMGFPTPEMMDEANYDLAYEKYKERFADAGDFHFYFVGNIDEKKLVDFASQYIASLPGKNSNEMYEVNDFRPLTGQHEKIIEKGADPKSSVRITYHGPTTYDTKEDFALETLGEILTIKLVEQLREEEGGVYGVGARGNMSNMPYDWYSFTIGFPCGPENVDKLKNAALAEVDKLVANGPTQKDLDKVKETYLLDHKEDMKDNRFWLNSLKNADYLKKDANKLMDYNKNVEGLTTEYLHEVAKKYLSGDYLVGIHNPES</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM95</accession>
    <name>A0A5C6ZM95_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD family hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_03380</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="234" mass="26886" checksum="C8CBAE1ADBC31B8A" modified="2019-11-13" version="1">MKRKYSNIKVIGFDADDTLWVNETYFREAELEVAKLMAPYETANTIDQELFRMEIKNLPLYGYGIKGFVLSMIEMALEISNYSISNESISKILDIGKDMLNKPVELLEGVEDSLKELSQTHRLILITKGDLLDQERKLEKSGLLKYFHHIEVLSDKQESNYSRLLKHLEVKPSEFLMVGNSLKSDILPLVNLKAEAVHVPFHTTWLHEQVDAEQSNGKAYATLKSLKELKKLLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMD2</accession>
    <name>A0A5C6ZMD2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cadmium-translocating P-type ATPase</fullName>
            <ecNumber evidence="8">3.6.3.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">cadA</name>
        <name evidence="8" type="ORF">ESY86_04920</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.3.3" evidence="8"/>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00941">
        <property type="entry name" value="CDATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="122"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="271"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="303"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="601"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="627"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD90093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="654" mass="70872" checksum="677F166980538B86" modified="2019-11-13" version="1">MKKKKVNLRDLDKTQHAGEHGKDDGHNHSSAESVSNFKTYIPAIFSFVMLMAGIAVDYFEAFPFFEGSLRVVWYTLAYIPVGLPVIKEGWKSIKNAAFFTEFLLMSIATLGAFAIGEHPEGVAVMLFYAVGELFQSAAVNRAKSNIQALLDVRPNEALVYRNSDFISVAPETVNIGETIQVRVGEKVPLDGVLLSEKGAFNTAALTGESKPDSIQKGAEVFAGSINLDGVIEIETTKEFKDSSIARILDMVQNATARKSKTELFIRKFARIYTPIVVFLAIGLTLLPYFFVDDYVFRDWLYRALIFLVISCPCALVISIPLGYFGGLGAASRNGILFKGASFLDAMTKVNTVVMDKTGTVTKGVFKIKDVKSLGMDVAEFMKYLMAMEAQSTHPIAKAILAYKADGADYQATNVTEIAGKGLKGTVNGKMLLVGNKALMLSNQIQVPTETDTIVESIVMVGIDGKFAGFVTIADELKDDAHKAIKEIRELGISKIIMLSGDKDSITQQVANELGIDWAKGGLLPEDKLNEVEKLKQQPVTKVAFIGDGINDAPVLATSDVGIAMGGLGSDVAIETADVIIQTDQPSKIARAIKIGRSTRRIVWQNIGLAFGVKIVVLLLGAGGLATMWEAVFADVGVALLAILNAVRLQKMKWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMI4</accession>
    <name>A0A5C6ZMI4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_01440</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001440">
        <property type="entry name" value="TPR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="1 2" id="KW-0802">TPR repeat</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022870800" evidence="3">
        <location>
            <begin position="20"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="295"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD91276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="425" mass="47093" checksum="822896194094BA5A" modified="2019-11-13" version="1">MKNQLIIVMALLFGTFSFAQKSELRDADKAIGSGNYADAKSALAIAEPMIAGADEKTQAKYYFLKGQALFANGTGSNADIDKAIENFEKVKVIEKQSGKEKYSSEIDDLKLEMINGILSKANTALQSEEYIKSSSGFEQAYRMSSKDTLYLYYAASTAVTAQDYKTSLKLYEELRDLGYQGVAMEYYATNKESGEEEAFDNKNLRDMSVRSGSHIAAKDKKTESKKAEIVKNIALIHLSNGDDVKALGAMEDARAANPDDLGLLISEANVQLKMGNKKRFKELMEEATTKDPNNAELQYNLGVIAAEAGEKEAAQKYYERAIELEPSYSDAYTNLSVLMLSGEAELVEEMNSLGTSAKDNKRYDELRDQRVQLYKSAIPYLETALKLKPNNIEAAKTLMNIYSITSDTDKFKTMKAQVESMEAGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMK4</accession>
    <name>A0A5C6ZMK4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glutathione peroxidase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_06655</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the glutathione peroxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004602">
        <property type="term" value="F:glutathione peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00340">
        <property type="entry name" value="GSH_Peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000889">
        <property type="entry name" value="Glutathione_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029759">
        <property type="entry name" value="GPX_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11592">
        <property type="entry name" value="PTHR11592"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00255">
        <property type="entry name" value="GSHPx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000303">
        <property type="entry name" value="Glutathion_perox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01011">
        <property type="entry name" value="GLUTPROXDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00460">
        <property type="entry name" value="GLUTATHIONE_PEROXID_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51355">
        <property type="entry name" value="GLUTATHIONE_PEROXID_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 5 6" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="4">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000303-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD89877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="180" mass="20641" checksum="788DBA06DC3D4D5A" modified="2019-11-13" version="1">MNPMKLFFQTLFKNPKTETKMAVDSIYDIKIKSLQDQALDLSQYKGKYLLFVNVASKCGFTPQYKELQELYDAHKEHLVVIGVPCNQFGSQEPGSSETIAEFCEVNYGVSFPITEKIDVKGSQQHPLYQWLTQKINNGQMDSSVKWNFQKYLIDPKGDYVDYYLSTTSPASSKITKHLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZML9</accession>
    <name>A0A5C6ZML9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_02890</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="165" mass="16999" checksum="1C7C68E4DC92AA98" modified="2019-11-13" version="1">MKTFITTLIFISFLIGNAQVDGVGIGTTTPKSTLDINGNLSVKVVELMGGGANAATPIDDGVYISLTPSSGSPEFILPDATTVPGRVYVLRNISDTQEAVIYTFGGDSAANSGAGVEFYAGNSRVSSESVVMMPDATGTPGSGERTKTLIFMSDGSNWTYGALGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMX0</accession>
    <name>A0A5C6ZMX0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Cold shock domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_00960</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04458">
        <property type="entry name" value="CSP_CDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012156">
        <property type="entry name" value="Cold_shock_CspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011129">
        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002059">
        <property type="entry name" value="CSP_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00313">
        <property type="entry name" value="CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002599">
        <property type="entry name" value="Cold_shock_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00050">
        <property type="entry name" value="COLDSHOCK"/>
    </dbReference>
    <dbReference type="SMART" id="SM00357">
        <property type="entry name" value="CSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51857">
        <property type="entry name" value="CSD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CSD" evidence="2">
        <location>
            <begin position="1"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD91189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="63" mass="7057" checksum="051F0DD846CD3F6B" modified="2019-11-13" version="1">MNKGTVKFFNDSKGFGFITEEGNNKEHFVHISGLIDEVREGDEVEFELTEGKKGLNAINVKVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN41</accession>
    <name>A0A5C6ZN41_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_02610</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023065994" evidence="2">
        <location>
            <begin position="24"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="86" mass="8854" checksum="BA1E965F5577B7C8" modified="2019-11-13" version="1">MMKKLVLNSALALALLVSVSSCRETEESNDNAADAVENSAENAAEATEGALESAGKAIDNAVNETKEAGEAVGEAVDSLDKQDDNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNI0</accession>
    <name>A0A5C6ZNI0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_00205</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042953">
        <property type="term" value="P:lipoprotein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015854">
        <property type="entry name" value="ABC_transpr_LolD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24220:SF654">
        <property type="entry name" value="PTHR24220:SF654"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD91057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="220" mass="24284" checksum="D5FCC3FCE71CFA38" modified="2019-11-13" version="1">MIKATNIHKNYGDLHVLKGVDLDIKKGEIVSIVGASGAGKTTLLQILGTLDQIDKKSASTLVINNTSIPELGDKALARFRNAHIGFIFQFHQLLPEFSALENVCIPAFIFGKTKTQAETRAKELLDFLGLSDRYHHKPSELSGGEQQRVAVARALVNNPELIFADEPSGNLDSESAENLHNLFFKLRDEFGQTFVIVTHNTELADMADRKLTMVDGRVMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNR8</accession>
    <name>A0A5C6ZNR8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Riboflavin biosynthesis protein RibD</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="10">Diaminohydroxyphosphoribosylaminopyrimidine deaminase</fullName>
                <shortName evidence="10">DRAP deaminase</shortName>
                <ecNumber evidence="10">3.5.4.26</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="10">Riboflavin-specific deaminase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="10">5-amino-6-(5-phosphoribosylamino)uracil reductase</fullName>
                <ecNumber evidence="10">1.1.1.193</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="10">HTP reductase</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="15" type="primary">ribD</name>
        <name evidence="15" type="ORF">ESY86_01100</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)-pyrimidine + H(+) + H2O = 5-amino-6-(5-phospho-D-ribosylamino)uracil + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:21868"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:58453"/>
            <dbReference type="ChEBI" id="CHEBI:58614"/>
            <dbReference type="EC" id="3.5.4.26"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>5-amino-6-(5-phospho-D-ribitylamino)uracil + NADP(+) = 5-amino-6-(5-phospho-D-ribosylamino)uracil + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:17845"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58421"/>
            <dbReference type="ChEBI" id="CHEBI:58453"/>
            <dbReference type="EC" id="1.1.1.193"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10 13">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="10 13">Binds 1 zinc ion.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Cofactor biosynthesis; riboflavin biosynthesis; 5-amino-6-(D-ribitylamino)uracil from GTP: step 2/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Cofactor biosynthesis; riboflavin biosynthesis; 5-amino-6-(D-ribitylamino)uracil from GTP: step 3/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 10">In the C-terminal section; belongs to the HTP reductase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">In the N-terminal section; belongs to the cytidine and deoxycytidylate deaminase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.26" evidence="10"/>
    <dbReference type="EC" id="1.1.1.193" evidence="10"/>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00275">
        <property type="reaction ID" value="UER00401"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008703">
        <property type="term" value="F:5-amino-6-(5-phosphoribosylamino)uracil reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008835">
        <property type="term" value="F:diaminohydroxyphosphoribosylaminopyrimidine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016192">
        <property type="entry name" value="APOBEC/CMP_deaminase_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004794">
        <property type="entry name" value="Eubact_RibD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002734">
        <property type="entry name" value="RibDG_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01872">
        <property type="entry name" value="RibD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006769">
        <property type="entry name" value="RibD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="SSF53597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00326">
        <property type="entry name" value="eubact_ribD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00903">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 10 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="10 12" id="KW-0521">NADP</keyword>
    <keyword evidence="10 15" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0686">Riboflavin biosynthesis</keyword>
    <keyword evidence="8 10 13" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="14">
        <location>
            <begin position="2"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="11">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="293"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR006769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR006769-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR006769-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR006769-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TXD91215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="350" mass="39349" checksum="7D7BD748E57D9916" modified="2019-11-13" version="1">MKIHEKYINRCIQIGENGLGTTAPNPMVGSVIVHEHCIIGEGFTSPFGGNHAEVNAIHSVKDKALLKNATLYVTLEPCSHFGKTPPCSDLIIKHKIPKVVIGCLDENPQVAGKGIANLEAAGCRVTVGILEAECKQHHKRFFTFHNKKRPYVILKWAETQDGFIAPKHKEKQEPVWITNPYSRQLVHKWRAQEQAILVGTNTVWEDNPSLTVRDWTGRNPLRFVLDQKLKLPQTANIYNRDAETLIITSEASKNKTLNPDWNLKYINWNLKHSIAKQICSILFKNNINSVIIEGGAQTLQNFINENLWDEARVFTGTNRFGTGVAAPQFSAELISETQLLNDTLIIYANN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNX0</accession>
    <name>A0A5C6ZNX0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cell division protein ZapA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_00785</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007838">
        <property type="entry name" value="Cell_div_ZapA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036192">
        <property type="entry name" value="Cell_div_ZapA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05164">
        <property type="entry name" value="ZapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102829">
        <property type="entry name" value="SSF102829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="97" mass="10786" checksum="FE54710609F0ADFB" modified="2019-11-13" version="1">MAEQLKIKLSIANRVYPLTIAPGQEEGLRSAAKKIETMIGQFEQNYSVRDKQDVLAMCALQFASQVEQKTIDTADVSHEVETKLEALNQLLQAHISA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPH7</accession>
    <name>A0A5C6ZPH7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phage tail sheath family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_00535</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the myoviridae tail sheath protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035089">
        <property type="entry name" value="Phage_sheath_subtilisin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020287">
        <property type="entry name" value="Tail_sheath_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04984">
        <property type="entry name" value="Phage_sheath_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17482">
        <property type="entry name" value="Phage_sheath_1C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phage_sheath_1" evidence="2">
        <location>
            <begin position="376"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="Phage_sheath_1C" evidence="3">
        <location>
            <begin position="458"/>
            <end position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD91327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="569" mass="62324" checksum="F1C22F494DF6DD16" modified="2019-11-13" version="1">MLEFEVLFGGVSPPASMNIDLATNIYDVTESQFKLYNSLRLFYANGGGDCYIVSIGSFDSAPDFSASTPFEDGLALLESFDEPTLILFPDAINLTAENLGLVQKAALTHCSELMDRFTIMDVRIASDLGTDLAAFRDQVGNRDLKYGAAYYPYLQSSFGHQFRYRDIVNGGVDFRAAHSSNSEITTAIDKFDEYQSDLDTLATACHDAKLANAKIDITSESNVNDYNASLWNLLRPLGDVSGSGLLETEVENAITGSLQSLAQRIFDFATAFNGLDDNTDITLVTGASDFIAPWEVSSTGPVSTPNPYDNQLNQNSDSDAADFSKVKNLLDKLHNQIVQSLNSLVANLRDLELQEENNLVSMLSEYSGIITRLNGTMNTVPPSGAMAGIYAYVDANRGVWKAPANVSLNGIIGLTDDVNYKEQATMNVHETGKSINAIRKFTGKGLLVWGARTLDGNSNDWRYINVRRLANMIEESCKKAAFNFVFEPNVKQTWVAVNGMISNFLSVVWRDGGLSGAKPEDAFFVSVGLGQTMTAQDILEGRMIVKIGYAPSRPAEFIVLEFTQMQQRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPP1</accession>
    <name>A0A5C6ZPP1_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Site-specific DNA-methyltransferase (adenine-specific)</fullName>
            <ecNumber evidence="2">2.1.1.72</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_01635</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:15197"/>
            <dbReference type="Rhea" id="RHEA-COMP:12418"/>
            <dbReference type="Rhea" id="RHEA-COMP:12419"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90615"/>
            <dbReference type="ChEBI" id="CHEBI:90616"/>
            <dbReference type="EC" id="2.1.1.72"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.72" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012327">
        <property type="entry name" value="MeTrfase_D12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02086">
        <property type="entry name" value="MethyltransfD12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00505">
        <property type="entry name" value="D12N6MTFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD91311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="353" mass="41496" checksum="69A207C1DB1886EC" modified="2019-11-13" version="1">MSNYPKVNYIGNKEKIASWICDQFPKDAKTLFDAFSGGCSLSYEAKSRGLEVCTNDVLKVNYHIANALIKNNATRLTQSDIDILFSGEPFEGFMFANYSEVYFFSEECKTLDLYRKNIEKLDSEAKKSLAFALIRRAMIRKMPYSRFNLSWEQIVQLRDEDYSYKKYKRRRAYHNKSFKFHVLNNLEAYNAAIFSNNKTHNAHNDDVFNVLDRIKADIIYLDPPYTGSMNNYFGFYGLMDDFIASEKTKPFEHHFMDKKSAISLFDTLFSKLSNFKYWYLSYNNSSYPSKEELLNLLHKYADNIKVIERKHVYKITGKEKKEKNKEFLFIVENKHHDKNQSKRTGQAICETAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZQU7</accession>
    <name>A0A5C6ZQU7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_00010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="246" mass="29584" checksum="D60DBBCD449BA387" modified="2019-11-13" version="1">MHLSKEIQRILVGLKSAVKLAETMDGTLPDRYAFYDKKGRSFSAEFAQTDKDFSIVLFERTEKPNYEKCFARGIFNDLNKISKLIVFWVVEQKSISNLKTEFKELEIYQDFDFKNLNPDIEKAWNKVKNRFFNDTKFWNNIEWRNRYSEMLIRTKMHPEFQNLFPFTSHYWLRFSPKKDFITECWTLDTYIVPIMHTKELPKELGNYYVSESENIDGNYFAELNEALDFYSIILKKTEPIKWITNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZRW8</accession>
    <name>A0A5C6ZRW8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Methylmalonyl-CoA mutase</fullName>
            <ecNumber evidence="8">5.4.99.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">scpA</name>
        <name evidence="8" type="ORF">ESY86_00595</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.2" evidence="8"/>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004494">
        <property type="term" value="F:methylmalonyl-CoA mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006159">
        <property type="entry name" value="Acid_CoA_mut_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016176">
        <property type="entry name" value="Cbl-dep_enz_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006158">
        <property type="entry name" value="Cobalamin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036724">
        <property type="entry name" value="Cobalamin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006099">
        <property type="entry name" value="MeMalonylCoA_mutase_a/b_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006098">
        <property type="entry name" value="MMCoA_mutase_a_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02310">
        <property type="entry name" value="B12-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01642">
        <property type="entry name" value="MM_CoA_mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51703">
        <property type="entry name" value="SSF51703"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52242">
        <property type="entry name" value="SSF52242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00640">
        <property type="entry name" value="acid_CoA_mut_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00641">
        <property type="entry name" value="acid_CoA_mut_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51332">
        <property type="entry name" value="B12_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0846">Cobalamin</keyword>
    <keyword evidence="5" id="KW-0170">Cobalt</keyword>
    <keyword evidence="4 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="B12-binding" evidence="7">
        <location>
            <begin position="581"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="10"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD91330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="708" mass="78332" checksum="6DB682676E325ADF" modified="2019-11-13" version="1">MMRKNLQHIQLEPEGNNNSTEASSASFKTAENIELKLQYSKTDLEHLEHLNFVAGISPYLRGPYSTMYVRRAWTIRQYAGFSTAEDSNAFYRRNLAAGQKGLSVAFDLATHRGYDSDHERVTGDVGKAGVAIDSVEDMKLLFDQIPLDKMSVSMTMNGAVLPIMAFYIVAAEEQGVAAEALQGTIQNDILKEFMVRNTYIYPPTPSMKIVSDIFEYSSKHMPKFNSISISGYHMQEAGATCDIELAYTLADGLEYIKKGLEAGMDIDTFAPRLSFFWAIGMNHFMEIAKMRAARMLWAKLVSRFNPKNEKSLSLRTHCQTSGWSLTEQDPFNNVARTTIEAAAAAFGGTQSLHTNALDEAIALPTDFSARIARNTQIYLQSETQITKTVDPWAGSFYVEKLTHDIAEEAWKLIEEVEELGGMTKAIEAGIPKLRIEEAAARKQARIDSGRDVIVGVNKYRRAEEDPITTLEVDNQTVRNGQIERLEHIKATRDSKKVTSALSNLTKAAKSGTENLLELAIEAARHRATLGEISDALEVEFGRYKAEIKSFSGVYSKEIKDDSSFQKARELADKFAEQDGRRPRIMIAKMGQDGHDRGAKVVATGYADVGFDVDIGPLFQTPKEAAKQAVENDVHILGVSSLAAGHKTLVPQVIEELKNYGREDIMVIVGGVIPQQDYQYLFDAGAVAVFGPGTKISEAAIEILDILMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZA47</accession>
    <name>A0A5C6ZA47_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20705</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000106">
        <property type="protein sequence ID" value="TXD85966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD85966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="154" mass="18037" checksum="160A38E7FCC12A58" modified="2019-11-13" version="1">MSIEVPIIILILAIPTYFICKWIMKRLKIGNDNNRKFIAVIPTIILSPIIYFGLVMIWIFFVSYYPTSSFDQSEWKSNIEERYKMSEDIIESEMLIGKNRDEVINILGNNYSTNNENRLSYELGFVPGLFNIDPDYLDIKFENEIVISVNQYEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAG4</accession>
    <name>A0A5C6ZAG4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20235</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000061">
        <property type="protein sequence ID" value="TXD86426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Exonuclease_RNaseT/DNA_pol3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="SSF52113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exonuclease" evidence="1">
        <location>
            <begin position="3"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="286" mass="32011" checksum="4C10C504D6213256" modified="2019-11-13" version="1">MNEFYVLDVETANADYSSICQIGLAKFENGELTEKWESLIDPDDYFDGMNISIHGITEKMVKGSPTFEEIYPKLKNILENKIVGHHMPFDRIAINRACELAELDLIEINWLDSAKIVRRTWEEFAYKGFGLANIADHLDIEFEHHNALQDAIATGKVMLKAFEKSEMTLEDWFGRVKRPINIYANGSTTIKLDGNPEGLLYGENIVFTGALMIPRAEAGKIASELGCNVSNSITKKTTMLVVGIQDTTKLAGYAKSSKHRKAEELINKGIGIRILSENDFSAITND</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZB46</accession>
    <name>A0A5C6ZB46_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Helix-turn-helix domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_19745</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000047">
        <property type="protein sequence ID" value="TXD86604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019109">
        <property type="entry name" value="DUF4870"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09685">
        <property type="entry name" value="DUF4870"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="HTH cro/C1-type" evidence="2">
        <location>
            <begin position="4"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="183" mass="20956" checksum="839006161189FDFC" modified="2019-11-13" version="1">MNKVKYFRESKNITQSELAEQSRLSLRTIQRIESGIEPKGHTLKMLAKVFDVECFELFEIPESCSNETDVIKSIKTLNTSILTFLIIPYGNIVFPLIIYFKNKKKEFRKVASDIISLQILWTLITSVLLILSPFIQDKFGFDSPLILWIGLLCFIVNLTVNFLNANSLNKVGKLKISSPISFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBC2</accession>
    <name>A0A5C6ZBC2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_20645</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000098">
        <property type="protein sequence ID" value="TXD86036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="274" mass="32466" checksum="38730DB37E41CCB6" modified="2019-11-13" version="1">MTLPEKINEVSTNSEIEIGVYPPNGFLQFEEASLGNGDNFGFYWEFGKENQEPIICEMIHDEGIIIPRFSNLDKFLDWYKLNDYDWGEEEIEDEKFVFSLLNKGNEYLKQNDPKKAIEFYKESTESFGEISENWFKLASQYKRIGNELGFQKSIINSIISNWAIEFPSQNAIRMIKSLNPVEELKNHPLIKNRENLEFNFGGRKENKDYLVIRKIIEELNENGDVNKALIMEQNYALKMYWETSSFQERNNFKLEEWKKKFKEKTKERIKINVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBF1</accession>
    <name>A0A5C6ZBF1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000030">
        <property type="protein sequence ID" value="TXD87061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022838990" evidence="1">
        <location>
            <begin position="20"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="236" mass="26633" checksum="F09F9811A78FC91C" modified="2019-11-13" version="1">MKKNYRIIFALLLAGLVFSCETRFEDDIRVLARGSVVNESGAAVADAEIAVFTRRGTSSIFSGSSSSDEFLLGRNQSQSDGTFEVISLFDRDLDFSIQITLDEDHTNYAYLTSTVEYLPDDLVFDLETVTLKTIGTVLFNISRISEEGTSMAYSFNYKDTRCVAYFVDGELDPDQSYCLEPITINRVLNDNRPDIENSFRTPFGTEVEFTYSINDAAPITETFIVNQSTYEFNFTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBF3</accession>
    <name>A0A5C6ZBF3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD(P)/FAD-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18835</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000034">
        <property type="protein sequence ID" value="TXD86924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="1">
        <location>
            <begin position="2"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="200" mass="21473" checksum="8CD183E1A2BBE452" modified="2019-11-13" version="1">MYDTLIIGGGAAGMSCALVLGSAQPKPFAANKHIGIIMHQRASHLQTALFNNVLGLAAGTLGADILETGKTQLAQLYPHVTQIETEKVKSVLKAPEGFAITTNKNTYHSKTIVVAVGYTNLVNIHGLQDYLEPHPRAALEKDRIWLKNEDHLVAEGLYVAGTMAGWRSQFAIAAGSGAQVATDILTLWNDGKHAKIHDKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBG9</accession>
    <name>A0A5C6ZBG9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_18285</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000030">
        <property type="protein sequence ID" value="TXD87081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010290">
        <property type="entry name" value="TM_effector"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05977">
        <property type="entry name" value="MFS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="113"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="180"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="230"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="267"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="299"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="385"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="10"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD87081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="424" mass="46483" checksum="049E284780AB8935" modified="2019-11-13" version="1">MQKKKDPYAALRFKEFNTFLLVRFFLVFGWSMQFIVIEWEVYSITKDPLSLGLIGLMEIIPALTMALFAGHIVDQKEKRNLLLLTIAAFSLISLGLFLLTWPEVVGDWETNTILYSIYALVFFGGFVRSFFGPTIFSLIALIVPKKIYPNAATWSSSTWQMASVLGPAFAGFSINWIGVHWSLCIIFGLVVLAFLVLLRVKKKPILNPKIGEPVMKSLREGLKFVFSNKAILGALTLDMIAVLFGGAVALLPIFAQDILKVGPEGFGVLRAAPAVGAFITMLITAYIPISKNAGMKLLIAVFCFGICIIVFGVSTIFWVSVIALFLSGVTDGVSMVIRQTILQLKTPDHMRGRVASVNSMFVGSSNELGAFESGVTAKLMGTVTAVVFGGTMTLITVATTGFLSPAFRKLDLTKDMEEHEREES</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBL9</accession>
    <name>A0A5C6ZBL9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3 4">Single-stranded DNA-binding protein</fullName>
            <shortName evidence="2">SSB</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ssb</name>
        <name evidence="5" type="ORF">ESY86_19080</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000036">
        <property type="protein sequence ID" value="TXD86860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04496">
        <property type="entry name" value="SSB_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00984">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000424">
        <property type="entry name" value="Primosome_PriB/ssb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011344">
        <property type="entry name" value="ssDNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10302">
        <property type="entry name" value="PTHR10302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00436">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002070">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00621">
        <property type="entry name" value="ssb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50935">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR002070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD86860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="111" mass="12392" checksum="4D0E35398BCC2051" modified="2019-11-13" version="1">MSTLRNKVQLIGNLGNDPEIVKLESGKTLAKFSIATNESYKNAKGELVKDTQWHNVVAWGKTAEVIEKYLTKGKEIAIEGKLTSRSYDDKEGVKRYITEVVCNEMVMLGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBM2</accession>
    <name>A0A5C6ZBM2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000025">
        <property type="protein sequence ID" value="TXD87406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022705263" evidence="1">
        <location>
            <begin position="23"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="313" mass="33457" checksum="8FB0C9AFBA2668DE" modified="2019-11-13" version="1">MKISFTKIASALLCLVLFTAVACENESFEGDFNTDGVAGCEVASLNTTQAALNFTGANIDNYALVCPNYKSALQAQILACNDANGNLQAILDTLGDCTEFTQPDDCATATAAVGVTQSAFSNATAENYTQLCNAYKAALENLIVQCGNDGGTQSEIEALGDCFNSNQPNAEVEGTWKLTAWMGENPIDLNNDAQESTNFLDEIDCYTDETLVFNAGGTGVSMSTSYANFDVQLETDSTNTYDYTVDCIAEVENTDFTWTQSGNSLTLIIAEQSYNYTIDGNSLSTLVPNGFTVSNADATITVTEDLTFVFTKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC14</accession>
    <name>A0A5C6ZC14_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19855</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000050">
        <property type="protein sequence ID" value="TXD86586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="162" mass="19287" checksum="E7603A3B907CD602" modified="2019-11-13" version="1">MTLTDLTNKENELYLFTINLYNGKVNSGSKDLTLDKVYAEYKNVHKEYAKMANKDIESLKRGLFIQWYSMTEPNYLTGIAELDEKSELKIIAELKNRIDKNTTDNELNWMLNHYLEWNYVFEKFKNIADLRKKENLKNLTNKKPKMINRGQMGIYWNSIIEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC28</accession>
    <name>A0A5C6ZC28_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplJ</name>
        <name evidence="6" type="ORF">ESY86_16310</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the ribosomal stalk of the 50S ribosomal subunit. The N-terminus interacts with L11 and the large rRNA to form the base of the stalk. The C-terminus forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05797">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00362">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022973">
        <property type="entry name" value="Ribosomal_L10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043141">
        <property type="entry name" value="Ribosomal_L10-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001790">
        <property type="entry name" value="Ribosomal_L10P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11560">
        <property type="entry name" value="PTHR11560"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00466">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160369">
        <property type="entry name" value="SSF160369"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00362"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD87595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="173" mass="18551" checksum="0D2E303A12559EEB" modified="2019-11-13" version="1">MTREEKSQVIEALTAQLADNPNIYLADISGLNAGSTSDLRRACYKANVQLHVVKNTLLAKAMEASDKEFGDLPSVLKGNTSVMYSETGNAPAKVIKNFRKKSDKPLLKGAFIAEAIYIGDEQLDMLVEIKSKDEVIGDIIGLLQSPAKNVISALKSSGGKLAGILKTLSEKEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC44</accession>
    <name>A0A5C6ZC44_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_19720</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000046">
        <property type="protein sequence ID" value="TXD86625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007492">
        <property type="entry name" value="LytTR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04397">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00850">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50930">
        <property type="entry name" value="HTH_LYTTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="3"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="HTH LytTR-type" evidence="3">
        <location>
            <begin position="138"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD86625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="240" mass="27600" checksum="FA98B0BDB1B043AD" modified="2019-11-13" version="1">MKTVLVIDDEEDARDLLKYYISQHSELSIIGEASNGIEAVKLVNQLKPDTIFLDIQMPGLNGFEVLARLDELPEVIFSTAYDQYAIKAFEVHAIDYLLKPYGKARFENALSRILNNQEQLIPLAESLLKLENRFPNKIILHKGSRKLVINTSSIIYAEAYGDYTKVFTDKVEYLSLKGISNLIENLNPDSFIRVHRSHFINKNCFVEIKKIERYHYAILADNTSIKISETYLPEIKKMLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC51</accession>
    <name>A0A5C6ZC51_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19595</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000044">
        <property type="protein sequence ID" value="TXD86647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043869">
        <property type="entry name" value="DUF5829"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19147">
        <property type="entry name" value="DUF5829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="309" mass="36050" checksum="756D342F852C5516" modified="2019-11-13" version="1">MKLKYIQVAFLAIVFLVGCKQEKKLPEDLLIGKHKIQAMLNKNPNNVLFNHFYVVLDSSTYALLRSNTFLNEQYAGMDRGMPHFNKINDTVTNIYLRGETHYLEILGPNNSFKEPVGQIGIGFSLGEQQPFSLNKSPEFIEEGTKFLRAWDTASFTIKDKRQIWYKAFYTFGMKTNLYTWYSYYNPEFLEAIDGEKRNVYTREDFLKKAYVPEKLFKNVVSITLNCNLADQYRIGKELQLLGCTLEKKEGEDLIFKAGDIYIKLILTRYKEKSQLLQMETTLNREDNRTLKIGTITIKTTGKKSFWTFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCN3</accession>
    <name>A0A5C6ZCN3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GIY-YIG nuclease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000037">
        <property type="protein sequence ID" value="TXD86807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035901">
        <property type="entry name" value="GIY-YIG_endonuc_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01541">
        <property type="entry name" value="GIY-YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00465">
        <property type="entry name" value="GIYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82771">
        <property type="entry name" value="SSF82771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GIY-YIG" evidence="1">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="88" mass="10732" checksum="444E99220DECFEC4" modified="2019-11-13" version="1">MFYIYAISSAHRNYIYVGMTESLEERFERHQSGRERTTKAYRPFKLIFSEALDVERKVAKKREKYWKSGIGKEKLRQLRDQKYITFTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD20</accession>
    <name>A0A5C6ZD20_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023143686" evidence="1">
        <location>
            <begin position="20"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="283" mass="32715" checksum="3CD04DE36A27B86F" modified="2019-11-13" version="1">MKTLLIIIVLLFSTAASYAQISVFDLIGEATEEAEGAANEEAAKNEAKAKAKALGDKEAEELINNFFNGFEKFAHESLTGKCLNLMGEYVTLLAYCDKRAKEATDPCEKKDWLGMESMILLAGTSISYCPQEFYYEDRQYYEKDISEYFFGIDLQKPNLEHPISNYFYSYYQMQKKFLAELGVDKYADLTPEEKVIFQSKDDQFHKEFSDNNLAELDPHFSLYMKFFFANIQLDILNYDMIMQYGLFGIRNYVSFVGEIFTPQFQLKKLIEIASMNDQIKCNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE70</accession>
    <name>A0A5C6ZE70_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">OmpA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_15335</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039567">
        <property type="entry name" value="Gly-zipper"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006664">
        <property type="entry name" value="OMP_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13488">
        <property type="entry name" value="Gly-zipper_Omp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01021">
        <property type="entry name" value="OMPADOMAIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023088947" evidence="3">
        <location>
            <begin position="27"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="OmpA-like" evidence="4">
        <location>
            <begin position="105"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD87843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="235" mass="24893" checksum="A44D6138A678632B" modified="2019-11-13" version="1">MKMITNRITILAVTALLSIGFTSCKAVDNANNKQKGAVIGATGGAILGAIIGNNVGKGGNGELGAVIGGVVGGGAGVLIGNKMDKQAKEIENEIPGAQVERVDDGIVVTFDEKSGVYFDTAKYNINDKSQATLNKLSGVFKEYPDTNILVVGHTDSVGSEDNNMTLSKNRANAVTDYMTNQGLSRSRFTTNWFGESQPMHDNSTVDGRSKNRRVNVAIVPNQQMINEAKQQAGEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEG5</accession>
    <name>A0A5C6ZEG5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_17780</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000028">
        <property type="protein sequence ID" value="TXD87165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="228" mass="26132" checksum="4CFDA8E46E70A8DF" modified="2019-11-13" version="1">MNKVYGLLLIGLLVVACKEKTTKNKLEDNKVEFNQTLADELSKMVITDQLAAANAYPPESHSNLSLEEWKSFKDSVFTTHQKRVKQIFDEHGFAGFDLVGEEGSSDFWLIVQHSDHNPEFQLEVLEKMKIEVDEGNADSRIYGLLVDRVKLNTGEAQIYGTQVAYNMQICQAYPRKLADSINVNKRRKEIGLEPLEVYLNDMTKMNFKMNKEFFAKKGVTKPKLYLTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEP0</accession>
    <name>A0A5C6ZEP0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_17560</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000027">
        <property type="protein sequence ID" value="TXD87241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="111" mass="13549" checksum="952B8C320DD47E51" modified="2019-11-13" version="1">MTTKSNNWTKTELKIYMLLLCANADTKETEEELKFIKSKVDAPTFERIYMEFKADTEDERFEKIDDNIQIHDFENKELAQMRREMHEIFYSDCDFKMLERNLDRIMDNILY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZER5</accession>
    <name>A0A5C6ZER5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Peptidase domain-containing ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">ESY86_14435</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005074">
        <property type="entry name" value="Peptidase_C39"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03412">
        <property type="entry name" value="Peptidase_C39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50990">
        <property type="entry name" value="PEPTIDASE_C39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="283"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="311"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase C39" evidence="10">
        <location>
            <begin position="10"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="174"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="489"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="523"/>
            <end position="530"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD88082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="730" mass="83293" checksum="F8005A92E8C5111F" modified="2019-11-13" version="1">MKKAFPFYKQTESKDCGPTCIKIVAKHYGKIIIIQNLRVLAETTRTGSTLLGLSDAAESIGLRAIGVNIALEKLQDVPLPCILHWNKNHFVVLYKIARNKFHVSDPAHGLLDYTKDEFLKRWVGNNADEKTREGIVLLVEPTAKFYTSEFETKDQKFGFSFLSKYLFKYKRFLWQLVIGLIAASILQLIFPFLTQSIVDVGIKNQDIHFIYLILFAQLALFIGRTAIEIIRSWILLHLSTRINISLVSDFFIKLMNLPIAFFDTRMTGDILQRINDHKRIERILTTSSLNVLFSMVNLVVFSFVLAYYSMILFGIFLLGSFLYFLWIIIFLKKRKDLDYKRFSVVSQEQSKVIELINGMQEIKLHNAEKQKRWSWEFLQARLFKVSIEGLALEQYQSVGSSFINEVKNIFITVLSAKLVIDGEITLGMMLAISYIVGQLNSPIAQLINFIREVQDAKISLDRLSEIHNKDDEEQQDIEKITTIPLDVDIQLSKVSFRYIGSDKLVLKDLDLVIPPKKVTAIVGVSGSGKTTLMKLLLKFYEPNSGTIKIGNHNLQQVSQKTWRHECGVVMQEGYIFNDTIAQNIAVGEDYVDKKKLAHAEDVANISEFIETLPLSYNTKIGMEGVGVSTGQKQRLLIARAVYKNPNFLFFDEATSALDANNEKTIMEKLDTFFENKTVVVIAHRLSTVKHAHQIVVLDKGKIVEVGNHNELVKQKGEYYHLVKNQLELGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEZ6</accession>
    <name>A0A5C6ZEZ6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_15750</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026487">
        <property type="entry name" value="CHP04141"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04141">
        <property type="entry name" value="TIGR04141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="102" mass="12008" checksum="84D1D2B99167854A" modified="2019-11-13" version="1">MKKTHKLSVFLLKPYVKKFKDAIKEEVRDYYEYKIKKQTEADGLIIIGSTRSNSPSWEQLLQQGVEKKIITLQNASNRAVLFFRVKERIFVITFGYGKHIIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF14</accession>
    <name>A0A5C6ZF14_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_15820</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="270" mass="29675" checksum="58D83EBB5A7DE913" modified="2019-11-13" version="1">MANLKWFPINPLLKEDGSFYSLSLMDNADELKPLYLEDDENPFSLFSVTQSSLNVQTAADLGISFGSANVSYKSFCLSYEAMLFTEKITTNPIGGKIYGTRWGAGLRVVLKVTDIESNASFNFGAIAAAAELGLAKVEYEIRGIGISSPSILKILPGPGEFNFANYNKILEAADKVKDYMSKNEDKLKPQPFQVFMSDELGRDIFKDSQSVIFAARNVMTRNSLSEALASAGAKFSPEIIMGFYAKVGILDDKTTPTRDDKKEAQSFLDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF59</accession>
    <name>A0A5C6ZF59_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">T9SS type A sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15295</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030916">
        <property type="entry name" value="ELWxxDGT_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04534">
        <property type="entry name" value="ELWxxDGT_rpt"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Por_Secre_tail" evidence="1">
        <location>
            <begin position="477"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="547" mass="60097" checksum="38060FC8671A6A37" modified="2019-11-13" version="1">MIKTMKTLNLISKRSIFLTIALFYCLTVLGQGAELVKDINPGPNYSDPKSYVEHNGLLYFQAFHSDYGSELWVTDGTENGTHLVKDMNPGGGYGAPAYLISYNGKLYFFASDGIHGYELWVSDGTTDGTVMLKDINTTGDSSPIPFIIFNNLLYFSADDGINGRELWVTDGTSEGTQLFYDISPGISSSSPSYVTEYNGNLYFSADDDVLGKELWITDGTVAGTNVLKDINPGAIGSSPYVYGVFNNLLYFTASDGIHGRELWTSNGTEAGTELLKDINTTAGSSNTAAGSSDPTNFKILDNHLIFTANDDVHGEELWRTDATADGTILIKDINPGSAQSNIKRFAELNGRLFFAADNGADGLKMWRSDGTPEGTSFFVDVSPGGGMDPSYYFVHYADALYFFSNYQLWVTDGTQQGTNNIPDIVPTTINNGTFSFKPYKNSLYFSSLADSEIGNELYKYTKEGLSVDDVNSISISIHPNPVDNLLFINTLSSIERVLIYDISGKIVNEKDYNLSTFQMDTSYLKSGIYFFNFVTKDGAQTHKIVKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF65</accession>
    <name>A0A5C6ZF65_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MGMT family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_14020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06445">
        <property type="entry name" value="ATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014048">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036217">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNAb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01035">
        <property type="entry name" value="DNA_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46767">
        <property type="entry name" value="SSF46767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00589">
        <property type="entry name" value="ogt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_binding_1" evidence="1">
        <location>
            <begin position="8"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="112" mass="12720" checksum="C81C4314D6775AFC" modified="2019-11-13" version="1">MLPETPSFFERVYVVVRQIPYGKVTSYGAIANYLGAKQSSRLVGYAMNNSHGKDVPAHRVVNRKGLLTGKHHFEGTNLMQQLLESEGIVVVENQIQEFDKVFWNPSEELRNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFA7</accession>
    <name>A0A5C6ZFA7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyltransferase family 4 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_16855</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000024">
        <property type="protein sequence ID" value="TXD87448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="364" mass="42379" checksum="B0AA7B56BE05D824" modified="2019-11-13" version="1">MPKVILISQFPLPYSKIGSWTTLYKNYLEADHHLIDIIICEPPNYDFEDVTYKFVKNNFTSKIKKKLTKEPYLEYLTNLKSIIIPNENYVVQIVDNFGLVKPLVNFLRSHNLRKSVYIQFFYHGFVPFYGNFQSRWFYDNIDEMVLLTRDSYINHLSFYTELPVIFSILHNGIDTSQFFEVSKETKQDLKNRLGINAKSVFIWCSQDRPKKGLDFIVNVWKSLGERVYDCELLVVGASRVEAIQGVKFLGRIPNDDLPKYYQVADVYLFPTLCQEGFGMSLIEALHCGCFCIASALGGVLEVLDYGKYGKLIEDPHFPNRWKDAILEYLNGSYEQTKLPKDKYSMNEWNKNMNGLIVAAKERMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFF0</accession>
    <name>A0A5C6ZFF0_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">L-glutamate gamma-semialdehyde dehydrogenase</fullName>
            <ecNumber evidence="3">1.2.1.88</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">L-glutamate gamma-semialdehyde dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">pruA</name>
        <name evidence="9" type="ORF">ESY86_16550</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + L-glutamate 5-semialdehyde + NAD(+) = 2 H(+) + L-glutamate + NADH</text>
            <dbReference type="Rhea" id="RHEA:30235"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58066"/>
            <dbReference type="EC" id="1.2.1.88"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid degradation; L-proline degradation into L-glutamate; L-glutamate from L-proline: step 2/2.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.88" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000023">
        <property type="protein sequence ID" value="TXD87504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00261">
        <property type="reaction ID" value="UER00374"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003842">
        <property type="term" value="F:1-pyrroline-5-carboxylate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010133">
        <property type="term" value="P:proline catabolic process to glutamate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07123">
        <property type="entry name" value="ALDH_F4-17_P5CDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005931">
        <property type="entry name" value="P5CDH/ALDH4A1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01236">
        <property type="entry name" value="D1pyr5carbox1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0642">Proline metabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="8">
        <location>
            <begin position="60"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032259"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD87504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="541" mass="59737" checksum="8C9D79910A4D4425" modified="2019-11-13" version="1">MGKGFFNTPIAINEPVKTYAPGSPERDEVLKAYKDMFNSKIEIPLHINGKDVKSGNTKTLSAPHDHQHVVGSYHLAEKSHVEDAISTAMEARKAWSQLHWEQRAGIFLKAAELIAGPYRAKINAATMIAQSKTVHQAEIDSACELIDFLRFNVQYMTDIYHDQPESTSEAWNRLEYRPLEGFTYAITPFNFTAIAGNLPSCMALMGNVVVWKPSDSQIYSAKVIMDVFDEAGVPPGVINVVFGDPKMITDTILASPDFSGLHFTGSTDVFKALWKQIGNNIDNYKTYPRIVGETGGKDFIVAHKTADAKQVATAITRGAFEFQGQKCSAASRAYVPSNIWEEVKKYVVADVKSFKKGSPDNLENYTTAVIHEASFDKLAKYIDQAKADADAEIIVGGTYDKSKGYFIDPTVIVAKDPKYTTMHTELFGPIITIYVYDADKFSETLKLVDETSPYALTGAILAKDRYAIAEATTALQNAAGNFYINDKPTGAVVGHQPFGGARASGTNDKAGSVLNLLRWISPRMIKETFVTPTDYRYPYMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFI8</accession>
    <name>A0A5C6ZFI8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_11675</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pseudouridine synthase RsuA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140098">
        <property type="term" value="F:catalytic activity, acting on RNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034470">
        <property type="term" value="P:ncRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042092">
        <property type="entry name" value="PsdUridine_s_RsuA/RluB/E/F_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000748">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB/E/F"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018496">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00093">
        <property type="entry name" value="TIGR00093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01149">
        <property type="entry name" value="PSI_RSU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PseudoU_synth_2" evidence="4">
        <location>
            <begin position="10"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD88624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="191" mass="21688" checksum="6C89E6AAC45F18F9" modified="2019-11-13" version="1">MQHQHFKLFKPYGYLSQFQSNAKHERNKRFLGELHDFPEGTMAVGRLDKDSEGLLLLTTDGQLSYDICNLGIEKEYYVLVSGVPTEAALIQLKSGVILSHKGETYLTKPCKVKLLSTPPDFPERNKKIRDERHGKSTWISITITEGKFRQVRKMTSKVGFPTLRLVRVRVGNITLEALKMGEVKALNELLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFP8</accession>
    <name>A0A5C6ZFP8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Rhodanese-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_16415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="28"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="120" mass="13550" checksum="371CC3DFF2DFD45A" modified="2019-11-13" version="1">MALGISCTSNRSSEVKVVTTEEMQSLLEMEDVQLVDVRSPEEFKTGFIKGAQNIDYRSSTFEEDILKLDKNKPVILYCKEGGRSSKCAKKMAEAGFVKIYDLDGGITQWQFEELDVEIIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFU0</accession>
    <name>A0A5C6ZFU0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_16535</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cysteine dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000023">
        <property type="protein sequence ID" value="TXD87501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016702">
        <property type="term" value="F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010300">
        <property type="entry name" value="CDO_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12918">
        <property type="entry name" value="PTHR12918"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05995">
        <property type="entry name" value="CDO_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0883">Thioether bond</keyword>
    <feature type="binding site" evidence="3">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="cross-link" description="3'-(S-cysteinyl)-tyrosine (Cys-Tyr)" evidence="2">
        <location>
            <begin position="82"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR610300-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR610300-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD87501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="180" mass="20834" checksum="75027E191B4D9990" modified="2019-11-13" version="1">MLKTPRQIQAFIDALKQAGIADYNGIFNTFDFSEVNFKDFTSWSDKSYTRNCLYHDSDFELILLCWCEGQETSVHNHDGEDCWVRILKGEIEEEFFDFNAEGDLNLLRSQIVTASETTFINDEIALHRLKNNFEGRSMSLHLYAKPIEQCRSYNEANGEFVKKELRYDSEQDVLDGTGTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFX5</accession>
    <name>A0A5C6ZFX5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12540</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030802">
        <property type="entry name" value="Permease_MalE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30188">
        <property type="entry name" value="PTHR30188"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02405">
        <property type="entry name" value="MlaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="185"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="225"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="246" mass="27163" checksum="67742A7F8E601CC7" modified="2019-11-13" version="1">MTYLHNIGTYFMMIGQMFHKPTKWSVMRRLVFKDIEDLIIGSLGIVSFISFFVGGVVTIQTALNIDNPLIPKSLIGFATRQSIILEFAPTFISIIMAGKVGSYITSSIGTMRVTEQIDALEVMGINAVNYLVFPKFVALMLYPFVISIAMFLGIVGGLAAVIFGDFGTVDDFITGVQLDFIPFHIFYAFLKTIVFAFVLATIPSFYGFYMKGGALEVGKASTTSFVWTSVVIILLNYILTQLLLST</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG21</accession>
    <name>A0A5C6ZG21_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MATE family efflux transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006603">
        <property type="entry name" value="DinF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="219"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="254"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="296"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="340"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="371"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="399"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="443" mass="48878" checksum="623648F56F19BC37" modified="2019-11-13" version="1">MLGHTFVSFVDNVMVGQLGTAELAAVSLGNTFVFIAMALGIGFSTAITPLLAEADTSNNFKDGKSAFKHGLFLCTVLGIALFLVVLLAKPILYQMGQPLEVVDLAIPYLDLVAFSLVPLIIFQAFKQFSDGLSMTKYPMYSTILSNLVNVVLNYVLIFGKFGFPEMGLVGAAYGTLVARFVMLWHLWWILTKKERSRRFVTQIKFFVLDKLMLKKLIHLGAPSAMQMFFEVLIFTSAVWLSGLLGKNPQAANQIALNLSSMTFMVATGLSVAAMIRVGNQKGLHRYHELRRIAISIVFLAICMAMCFAILFAVFNEALPKLYVDYDDVVNFEDNMEVIKIASTLMLAAAIFQISDSIQVVILGALRGMQDVMMPTFITFVAYGLIGFPVSFFLGKEEAYGSFGIWMGLLAGLSSAAILLWIRFNYLTKALILKSSNLKQHGTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG41</accession>
    <name>A0A5C6ZG41_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA-dihydrouridine synthase</fullName>
            <ecNumber evidence="1">1.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_11585</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the dus family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.-" evidence="1"/>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017150">
        <property type="term" value="F:tRNA dihydrouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001269">
        <property type="entry name" value="DUS_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006621">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="1" id="KW-0288">FMN</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Dus" evidence="3">
        <location>
            <begin position="8"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR006621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006621-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="321" mass="36590" checksum="9122F1022AB874A8" modified="2019-11-13" version="1">MASTLLSSPLQGFTDFRFRNAFNQYFGGIDTFYSPYIRLNGKLKIKQSYQNDLLPENNSSLEVIPQIITNDADEFVYVAKYVQSLGYKELNWNLGCPYPMVAKSGMGAGLICNPNKINDVLHKAHNETDILVSMKMRMGYENAEEILDAFTILDQYPLKNIAIHARIGKQLYKGPVDLDAFEKCIGSTRHTLYYNGDITSVSAFKAIEARFPGIDHFMIGRGLIADPFLPSMIKNNTTEYPENRWAIFSEFHDTIYQQYDAFLSGPTPIKMKMLGFWEYFSQATSNPQKTYKAIKKASNPIKYKQAVAQILNTEMKVTRSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG47</accession>
    <name>A0A5C6ZG47_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 14">Undecaprenyl-diphosphatase</fullName>
            <ecNumber evidence="4 14">3.6.1.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13 14">Bacitracin resistance protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12 14">Undecaprenyl pyrophosphate phosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">uppP</name>
        <name evidence="15" type="ORF">ESY86_13875</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>di-trans,octa-cis-undecaprenyl diphosphate + H2O = di-trans,octa-cis-undecaprenyl phosphate + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:28094"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58405"/>
            <dbReference type="ChEBI" id="CHEBI:60392"/>
            <dbReference type="EC" id="3.6.1.27"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Cell membrane</location>
            <topology evidence="14">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="14">Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the UppP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.27" evidence="4 14"/>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050380">
        <property type="term" value="F:undecaprenyl-diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016311">
        <property type="term" value="P:dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01006">
        <property type="entry name" value="Undec_diphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003824">
        <property type="entry name" value="UppP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30622">
        <property type="entry name" value="PTHR30622"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02673">
        <property type="entry name" value="BacA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00753">
        <property type="entry name" value="undec_PP_bacA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="6 14" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="14" id="KW-0133">Cell shape</keyword>
    <keyword evidence="14" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="8 14 15" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="215"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="247"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00032932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TXD88183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="270" mass="29975" checksum="D0C49BD6E29550D0" modified="2019-11-13" version="1">MNLIEAIILAIIEGITEYLPVSSTGHMIIASSFMGIATDDFTKLFTIVIQLGAIIAVVVLYWKRFFQSLDFYFKLLVAFLPAVVLGLLLNDVIDELLESPITVAISLIIGGFILLKVDDWFKANEVEDPQNPEAHTQISYLTALKIGFFQCLAMIPGTSRSGASIVGGMTQKLNRKTAAEFSFFLAVPTMFGATAKKGYDYYQAGFVLTSNQINYLIIGNVIAFIVALLAIRSFIDYLSKKGFKIFGYYRIVLGVALLIIHFFIYRLTTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGA9</accession>
    <name>A0A5C6ZGA9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DNA mismatch repair protein MutS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_11745</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045910">
        <property type="term" value="P:negative regulation of DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005747">
        <property type="entry name" value="MutS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS_family"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="PTHR11361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361:SF14">
        <property type="entry name" value="PTHR11361:SF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005814">
        <property type="entry name" value="MutS_YshD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="SSF48334"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MUTSd" evidence="5">
        <location>
            <begin position="12"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_MISMATCH_REPAIR_2" evidence="6">
        <location>
            <begin position="335"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="541"/>
            <end position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD88710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="721" mass="82615" checksum="303C8A4C21CAC16F" modified="2019-11-13" version="1">MVNIHEKTLQDIEFHSVLNQVAALCITDLGRAEVNAIAPFKDHEETLISLGFTNEYLASFYNDNRIPNHGFDAISKELQLLKIENSFLETKSFQKIASISLSVNAILKFLKKFAEYYPSLAQKSAQIEMTTAVIEEIDSIVDRFGEVKDDASQELYQLRKAINSIRGKINQSFTSALNTYHNLDYLDDIRESVVENKRVLAVKAMYRRKVKGSIMGNSKTGSIVYIQPETTFQYARELNNLEYEEKEEVDNILKQLTEYARPFRPLFKAYQEFLTHLDLIYAKAKYAQSINAILPNINTEKIYEAIDAFHPLLYASNQKEKKTTFSQSIKLKKDNRIIVISGPNAGGKSITLKTIGLLQVMLQSGLLIPVHEKSNLCFFDRIMSDIGDNQSIENHLSTYSYRLKQMHYFLRKCNKNTLFLIDEFGTGSDPELGGALAETFLEEFYHREAFGIITTHYSNLKVLANELPFMQNANMLFDEKSLEPMFKLALGQAGSSFTFEVAQKNGIPFSLINRAKKKIERGKVRFDATIAKLQKERSKLEKTERSLKENEKKKQSEADKLEEVNAKVQKKLENFQELYDSNQRLIYLGQKVNDIAEKFFDDKKKRPLMDELFRLVQIENSKRQKVSAKQKKAVKTKEAQIKEEAEKKVDVIRKKKKATKLKSKAVEKPKPTLKLGDRVRMHDGKAVGSIDAIEKNKAIVNYGMFTTHVNMDLLELVEASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGC4</accession>
    <name>A0A5C6ZGC4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADP oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10930</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028939">
        <property type="entry name" value="P5C_Rdtase_cat_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03807">
        <property type="entry name" value="F420_oxidored"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F420_oxidored" evidence="1">
        <location>
            <begin position="2"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="208" mass="22937" checksum="430C616EB1720FE5" modified="2019-11-13" version="1">MKIGVIGSGNIGGNLGKHWAKAGHEVLFSSRHPEQLGDLVRECEGNAKAVSVAEAFEANADVYLLATPFKAIDELAELYAGEYGDRVIIDATNPYPERDGKMAKDVKESNRNASEYIAMKFNTAKTAKAFNTIHAEHLKNRAWRTNDKIAIPFAAQDADSSAKTKQLIEDIGFDSVYVGDLTKTKQMDPDQKLYGKSVGRQELEDLMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGE9</accession>
    <name>A0A5C6ZGE9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Translation initiation factor IF-1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2 5" type="primary">infA</name>
        <name evidence="5" type="ORF">ESY86_14935</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the IF-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_026753784.1">
        <property type="nucleotide sequence ID" value="NZ_VORO01000018.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04451">
        <property type="entry name" value="S1_IF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00075">
        <property type="entry name" value="IF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006196">
        <property type="entry name" value="RNA-binding_domain_S1_IF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004368">
        <property type="entry name" value="TIF_IF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33370">
        <property type="entry name" value="PTHR33370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01176">
        <property type="entry name" value="eIF-1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00008">
        <property type="entry name" value="infA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50832">
        <property type="entry name" value="S1_IF1_TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2 3" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="2 3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="S1-like" evidence="4">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD87962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="71" mass="8094" checksum="00EC8C30BBD22357" modified="2019-11-13" version="1">MAKQAAIEQDGSIIEALSNAMFRVELENGHIVTAHISGKMRMHYIKLLPGDKVKLEMSPYDLTKARITYRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGG4</accession>
    <name>A0A5C6ZGG4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">FtsX-like permease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_13390</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="282"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="335"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="373"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="421"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="689"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="738"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="772"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="20"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="311"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="463"/>
            <end position="603"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD88297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="809" mass="90366" checksum="3D5A39C896328FEC" modified="2019-11-13" version="1">MIRNHFKIALRYLFKNKLYSILNIVGLALGIAAFVIITLYVGYERSYDKFEGSDEVFRVYMDYAEGGNFVPGDAQTYNLSGPTLKKEFPEIIEQVRLYRLEKVTFVNGEKIIQQPNGSLADASYFKIFDHPLIEGNLSDFEKPNTIILTKTLAKKLFGKKQVLGKSLEVFDGNGIRLEIVGIINDIAQNTHYKTNFLISYPTMNTWDMGNNAKPNWSGNNFFTYLKVAPGIDKIALRKKIMMSDFEQDPDERHNIEAISDIHLHSDKPFEAETNGSLSRVRFLSAIGFIILILSWLNYVNLATAKSMERSKEVGIRKVAGAQRSQLIVQSLGESLLLNLFAVALAIGLAYVLLPLFNNFVGKELVLGLSNLGIILPYLAFILLGTLVSGLYPAMVISGFSPIRALKGKVVASRGGVNIRKGLIGVQFFATVVLIIGTLVVSQQISFLGEQPLGVDLSQLVALKGELLSNENDSITRQKSVVLESELSQLPFVKGVTQAKTYPGDGYDNLSSNVGITYPDGTSNERLLFYLYGAQPNYFEVLGIDFLAGKTYLRKNPGVHNFDIVINETFARIMGFTDMSEIIGKNVKFWDETWTVTGVFEDYHHFGLKSKIEPMFIGDINWAFGTGLQNVLVKMDATGLSLSVMDKNLDQIQQKWKTIFPQSTLDYTFLDKKFEAQYKEDTKFGAAFQLFTGLAIFIAGLGLFGLTSYTILQRKKEIGIRKVSGASVLQILTLLNRDFLKLVTISFILAAPIAWYVMNQWLQEFAYQTRLNWWVFALAGIAAFLVAIISVSFQAIKAAIANPVKSLRTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGG5</accession>
    <name>A0A5C6ZGG5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_15745</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="2"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="220" mass="24977" checksum="83D677A9958EDB52" modified="2019-11-13" version="1">MNILIIDDHPQIAESFKSALHKIALNNSRFKFEITEETTLDGSYALLTDSKKIFYDLIFLDIKLPSSKDGKLLSGEDLGLEIRKQSPKSKIIVATTYNDNYRINNIFRNLSPEGLLIKNDLTPKVLVNAIEEVLDDSLAYTKTVKKLLRILASNDISLDYVDRQILYQLSIGTKMMDLPNVITMSIGGIERRKRQLKEAFDIVGKDDKVLLKIARDKGFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGN0</accession>
    <name>A0A5C6ZGN0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_09535</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="187" mass="21604" checksum="32EE45032D0E6E8E" modified="2019-11-13" version="1">MKSFAIILLTFFSFSFNTSFYSNLEYVKTDTQEILKTFKLYSGRLYIKLPSEFGLMSEEIKKVKYPTSDPKAITVCTNKESTINILLELSKKPLNQNRLPVILNQIQSEFSRIPEIQLENAEIQSVNEKDILVVEFISEAVDGRIYNLMFITNIDGYTFTSNFNCTIENMPKWKPIGKQILNSLKEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGY7</accession>
    <name>A0A5C6ZGY7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidoglycan synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_12405</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016881">
        <property type="term" value="F:acid-amino acid ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000713">
        <property type="entry name" value="Mur_ligase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01225">
        <property type="entry name" value="Mur_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="2" id="KW-0133">Cell shape</keyword>
    <keyword evidence="5" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase" evidence="6">
        <location>
            <begin position="3"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_M" evidence="8">
        <location>
            <begin position="108"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="7">
        <location>
            <begin position="305"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD88536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="453" mass="50884" checksum="879EB0B975580178" modified="2019-11-13" version="1">MNVHFIAIGGAAMHNLAIALHHKGYQVTGSDDEIFDPSKSRLEAVGLLPERFGWYPEKISANLDAIVLGMHAKADNPELLMAQELGLTIYSYPEFLYEQSKHKTRVVIGGSHGKTTITSMILHVLHYHDRDVDYMVGAQLEGFDVMVKLTDDNDFIVLEGDEYLSSPIDRRPKFHLYKPNIALLSGIAWDHINVFPTYENYVEQFSIFVDSIVSGGSINYNEEDPEVKRVVEASDNAIRKIAYSTPDYHIEDGQTFLTTPEGDLPVAVFGEHNLNNLAGAKWICQHMGIDEDDFYEAIASFKGASKRLEKIAETKNTVAYKDFAHSPSKVEATTKAVKAQYNNRNLVACLELHTYSSLNAEFLKEYKGALDAADTAVVFYSPHALEMKKLEPISKSQIADAFERDDLIIYTDAEAFKDFLYAQDFKNKTLLLMSSGNYGGLDFDELRTFLESQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH07</accession>
    <name>A0A5C6ZH07_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_14770</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022780547" evidence="2">
        <location>
            <begin position="28"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="173"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="300" mass="34350" checksum="7BD87E3FA409B3C4" modified="2019-11-13" version="1">MSITLMKTHMKKSVLILIIAICTQFTAWSQEQINAYKYVLIPNQFEFLSAKDQYQINSLTKFLFNKYGYTAFLEDEELPEDLKRDRCLALKADVNKVSGGFLKTKLQMSLLDCNNKVVAASKVGETREKKYEVAYNLALREAFETFQNFDYAYQPTSDSNSKMDDTKADVAAIKDQKAAKKEIERLKNEVESLKNKEREAVSQVEKQVIKAESKTEVMPSAPKNTIVEDTADLLYAQPLDNGYQIVDTEPKKVMILLNTGVQNTFLVKGKDAIVYKRGNTWVYESYETEKLETKTLNLKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH31</accession>
    <name>A0A5C6ZH31_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="85"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="144" mass="16823" checksum="AC609C729706D1C3" modified="2019-11-13" version="1">MIWKNLIDFWCNEKGRYGLTVPFLVGAERLTRRTTIKSLLNEINESDSDFIISNCGDLDEYVVGTHKPEYAYINTLKRFDSLILNDNELAKAKTIKELIEKVENKYKYLIENGLYSKDYNSGKWTAFNNEDLELIKLNELSKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI07</accession>
    <name>A0A5C6ZI07_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="18">Polysaccharide biosynthesis tyrosine autokinase</fullName>
            <ecNumber evidence="18">2.7.10.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">ESY86_09905</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-tyrosyl-[protein] = ADP + H(+) + O-phospho-L-tyrosyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:10596"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:10137"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:82620"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the etk/wzc family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.10.2" evidence="18"/>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004715">
        <property type="term" value="F:non-membrane spanning protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045226">
        <property type="term" value="P:extracellular polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009103">
        <property type="term" value="P:lipopolysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005702">
        <property type="entry name" value="EPS_synthesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003856">
        <property type="entry name" value="LPS_length_determ_N_term"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02706">
        <property type="entry name" value="Wzz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01007">
        <property type="entry name" value="eps_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 18" id="KW-0418">Kinase</keyword>
    <keyword evidence="13 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 18" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="14" id="KW-0829">Tyrosine-protein kinase</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="493"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="domain" description="Wzz" evidence="16">
        <location>
            <begin position="28"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="AAA_31" evidence="17">
        <location>
            <begin position="581"/>
            <end position="726"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="TXD89079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="778" mass="86961" checksum="3BE0934AB7FB2EFB" modified="2019-11-13" version="1">MNQDQKSMTAQKNDQGEVIKSEIIKYLRYWYWFAICIVLALLGAYLYLRYTPNIYSSTAKIKILDKGKGLELPSSAFVFNRSNINLENEIEIIKSYRIIEQAVKQLDLTMGFYEVGNVLTTEINQFPFKFVKTIPNDSISNYRQYRIEVNKNGFNVFEGASENATLIGNYNSYNVAHDLPFELQFENGEAAKPYLGHSYLLRLSPLAGATRKLKGALNVSMLGKGSDLLKLSHSSQSWTRSERTLNAVIDVFNRDGINDRQQISKRTIDFIDERFKSLAMELDSIEVDIKDFKRSNNFINLESDAEVSLTQQTMAEGQVFDVENQLIITDLLEETLGADNAESDLLPANIGIGDNNINGLIDQYNELVLQRDNFAVSGGENNPTIKILNDKLKNVKSNINASIDSYKAQLNASKQQLVKRNQRYAGQVSSLPLKEKLMRSRIRQQEIKQTLYLFLLQKREEAAINLAITEPSIKVVEYALSSGGPISPNSRNIYLMALIAGLAVPFAAIYGFNLLNTKIKGKNDVVNSVGDIPILAELPRIKGDKLVFDNPTDRSVQSEAFRILSANVNYILPATDSDQGKVIYCTSTIKGEGKTYVGMNLSLALSSINKKVLLIGADLRNPQIHSYVAHEKNEVGLSNFLHDDSSDWKAAIIHGFEKHPNHDILLSGSIPPNPTQLLTNGRFEQLITEARAIYDYIIVDTAPTILVTDTLLISRLADATIYLVRADYTEKNLLEFSKGLNNAGKLKNMAYVINGVGSSKAYGYSYNYGYGYGYGGNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI14</accession>
    <name>A0A5C6ZI14_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Adenosylhomocysteinase</fullName>
            <ecNumber evidence="4">3.3.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">S-adenosyl-L-homocysteine hydrolase</fullName>
            <shortName evidence="4">AdoHcyase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ahcY</name>
        <name evidence="9" type="ORF">ESY86_08510</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 6">
            <text>H2O + S-adenosyl-L-homocysteine = adenosine + L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:21708"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
            <dbReference type="EC" id="3.3.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4 6">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
        <text evidence="4 6">Binds 1 NAD(+) per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 6">Amino-acid biosynthesis; L-homocysteine biosynthesis; L-homocysteine from S-adenosyl-L-homocysteine: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 7">Belongs to the adenosylhomocysteinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.3.1.1" evidence="4"/>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00314">
        <property type="reaction ID" value="UER00076"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004013">
        <property type="term" value="F:adenosylhomocysteinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00401">
        <property type="entry name" value="SAHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1480">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00563">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042172">
        <property type="entry name" value="Adenosylhomocyst_ase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000043">
        <property type="entry name" value="Adenosylhomocysteinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015878">
        <property type="entry name" value="Ado_hCys_hydrolase_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020082">
        <property type="entry name" value="S-Ado-L-homoCys_hydrolase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23420">
        <property type="entry name" value="PTHR23420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05221">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00670">
        <property type="entry name" value="AdoHcyase_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001109">
        <property type="entry name" value="Ad_hcy_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00996">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00997">
        <property type="entry name" value="AdoHcyase_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00936">
        <property type="entry name" value="ahcY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00738">
        <property type="entry name" value="ADOHCYASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00739">
        <property type="entry name" value="ADOHCYASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 4 6" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4 6" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AdoHcyase_NAD" evidence="8">
        <location>
            <begin position="197"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="163"/>
            <end position="165"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="226"/>
            <end position="231"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="249"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="284"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="305"/>
            <end position="307"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="352"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001109-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD89416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="438" mass="48545" checksum="8A8631AD50E72986" modified="2019-11-13" version="1">MNTKTTTYVPYKVKDMSLAAWGRKEIELAEAEMPGLMSLREEYGASQPLKGARIAGCLHMTIQTAVLIETLIALGAEVTWSSCNIFSTQDQAAAAIAEAGIPVYAWKGMNEEEFDWCIEQTLFFGEDRKPLNMILDDGGDLTNMVFDRYPELQEGINGLSEETTTGVHRLYERMKKGTLSMPAINVNDSVTKSKFDNKYGCRESAVDAIRRATDLMLAGKRVVVCGYGDVGKGTAASFKGAGSIVTVTEIDPICALQAAMDGFEVKKLENVVGKADIVITTTGNKDIVQGHHFEAMKDKTVVCNIGHFDNEIDMAWLKKNHGKSHVEIKPQVDKYTLGGKDVIILAQGRLVNLGCATGHPSFVMSNSFTNQTLAQIELWTNRDAYENEVYMLPKHLDEKVAKLHLEKIGVELTELRNDQAEYIGVEVEGPYKPEYYRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI67</accession>
    <name>A0A5C6ZI67_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10305</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="70" mass="8432" checksum="23E28D566D3D288A" modified="2019-11-13" version="1">MTEDGRKTGDGRRKTEDGRRKTQDARRNIEYRIENFERPMMKWFLVEVSTLRKTGEDGRRKTGDVRRKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIC7</accession>
    <name>A0A5C6ZIC7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleotidyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07705</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="1">
        <location>
            <begin position="7"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="339" mass="37133" checksum="74E73ED1C6118A7C" modified="2019-11-13" version="1">MKIIVPMAGRGSRLRPHSLTVPKPLIPVAGEPIVNRLVKDIAKVLKQPIEEIAFILGDPAWFGDDVVENLKALARSLGAKPSIYRQDQPLGTGHAIMCAEPSLSGPAVVAYADTLIRAEFDLDPEADSVIWTKNVKNPEAYGVVKLNDKQEIVELVEKPESFVSDQAVIGIYYFKDIEVLKNKLQEVLDENVMNGGEYQINDGIKRMMAEGKVFKTGTVDEWMDCGNKAVTLDTNAKMLGFLKADGEEQLISDSVTLNNSTIIEPCFVGDNVVLNNTTLGPNVSVGKHCVIENCTIKNSLIQTHTTIKNAHLDQAMIGNHVRYDGNFKAVSIGDYSVLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZID7</accession>
    <name>A0A5C6ZID7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">BrxA/BrxB family bacilliredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_07290</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009474">
        <property type="entry name" value="YphP/YqiW"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40052">
        <property type="entry name" value="PTHR40052"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06491">
        <property type="entry name" value="Disulph_isomer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04191">
        <property type="entry name" value="YphP_YqiW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="136" mass="15012" checksum="32E391A239732F0C" modified="2019-11-13" version="1">MYPAELVKPMREDLTKVGFEELHTSDEVKTALSKEGTTLIVVNSVCGCAAANARPGARMSLQNTKRPEHIVTVFAGVDKEAVDEARSHMVPFPPSSPCMALFKDGELVHMLERHHIEGRPAELIAENLMDAYNQHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIP5</accession>
    <name>A0A5C6ZIP5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Purine nucleoside phosphorylase</fullName>
            <ecNumber evidence="3">2.4.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Inosine-guanosine phosphorylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_09105</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 3">Purine metabolism; purine nucleoside salvage.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the PNP/MTAP phosphorylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.1" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00606"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004731">
        <property type="term" value="F:purine-nucleoside phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09009">
        <property type="entry name" value="PNP-EcPNPII_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011268">
        <property type="entry name" value="Purine_phosphorylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11904">
        <property type="entry name" value="PTHR11904"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000477">
        <property type="entry name" value="PurNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="SSF53167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01697">
        <property type="entry name" value="PNPH-PUNA-XAPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PNP_UDP_1" evidence="4">
        <location>
            <begin position="22"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD89206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="270" mass="29851" checksum="8C97EA93F43D2127" modified="2019-11-13" version="1">MQKYITETADYLKNKGFDTPEIGIILGTGLGQLVNELEILEEVSYNHIPNFPTATIEFHKGKLIYGILEGKKVIVMQGRFHIYEGYSLQDVTYPVRVMKALGIHTLLVSNASGAINLDFKKGELMLIDDHINLQGSSPLAFKGVEQLGERFVDMSAPYDLDINAKFKTIAKAHKIKLHEGVYASVVGPQLETRAEYRMLKIMGADAVGMSTVPEIIVANHLNLKAAAVSVLTDECDPNHLKPVNITEIIAMATKAEPDMIVLFKELIKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-02-10" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIR0</accession>
    <name>A0A5C6ZIR0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">BamA/TamA family outer membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_10000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000184">
        <property type="entry name" value="Bac_surfAg_D15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010827">
        <property type="entry name" value="BamA/TamA_POTRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039910">
        <property type="entry name" value="D15-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12815">
        <property type="entry name" value="PTHR12815"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01103">
        <property type="entry name" value="Omp85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07244">
        <property type="entry name" value="POTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="POTRA" evidence="3">
        <location>
            <begin position="107"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="Omp85" evidence="2">
        <location>
            <begin position="483"/>
            <end position="824"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="851" mass="97126" checksum="9B440CE669134B93" modified="2019-11-13" version="1">MLTFSGLKSHILNKFLIIALVALLSSCDVMKRVGKEQHLLVDNTILVDGKKTSNETTNSLLYQKPNGRLPLLGAPLRLHIYNLARPNIDSIIQAKVLDHPKKVAWKTKVLSEKQFLKELQSRKNFNNWLKKTGEAPVIYDEKRAEKTSTQLRKYYFSKGWFNASSAFEVDKDSSQKARVTYKVTKGVPYVLDSISSYIATPSIDSLYNASLSGNSLIKKGQQYDAVNYSKERDRLTERLRNSGYYHFAQDYISFDLDTINTNNKVHTELIIANRAIRTVDSIIRRPFKTYKVKEVNIFTDYSYENRALPISDSVQFKNYNLYSYDKLKFRPKAITDAIFITKDALFRDLDRSRTYRYLSELRAFRYPNIEYIENEQDSSLTANVYLIPRKKFELNSSFEVSQSNIQTVGFAFSGGLSIRNIFRGAETLEISALGAIGSSVDANNNSNQFFDINELGANIRLIIPRFFLPFNTEEIIPKFMSPGTRVNLSATSQTNIGLDKQSFTGTLNYNWYPSNEVTNNLDLFNIQFVKNLNVGNYFRVYNNSYESLNTIARRANYIPDDLELGYPEGADIFISEVINNNTSLQPTNPDFINVNNIKQRKDRLTEDNLIISSSFNYIKDRRENLYDRNFSILRGRVELAGNLLASLSGVFDLSANNNGQSTVFGVPFSQFTKLELDYVKHWDLGNKSEFAIRSFFGIAIPYGNSTNIPFPRSFFGGGPNDIRAWSAYNLGPGSSQSTDEFNEANMKITLSAEQRFNILGRFYGAAFVDAGNIWNVFDDVNEDARTFDSFGSLKDMAIGSGFGVRYDFSFFVLRFDVGFKTYDPSRALGSRWFKDYNFKNAVYNIGINYPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIU5</accession>
    <name>A0A5C6ZIU5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Magnesium transport protein CorA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 7" type="primary">corA</name>
        <name evidence="7" type="ORF">ESY86_10525</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Mediates influx of magnesium ions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015087">
        <property type="term" value="F:cobalt ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045861">
        <property type="entry name" value="CorA_cytoplasmic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004488">
        <property type="entry name" value="Mg/Co-transport_prot_CorA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002523">
        <property type="entry name" value="MgTranspt_CorA/ZnTranspt_ZntB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01544">
        <property type="entry name" value="CorA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143865">
        <property type="entry name" value="SSF143865"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="SSF144083"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00383">
        <property type="entry name" value="corA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="298"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="330"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD88922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="356" mass="41935" checksum="1E6095138DA38226" modified="2019-11-13" version="1">MNLKKKKKSYKVKNLSPGTMAYRGKKQTTAISIDIINYNGDSYKREHSNRVEDAFNHKGNDQVTWININGLNNIKEIETIGLHYELHPLTLEDIVNTHQRPKIDEFENHLYIVFKMLYFKDDDQLTKEHVSMIVGKDYILTFQEADGDVFDDLRDRINSTKGRIRMRGADYLMYAILDAIVDNYFSVIEAFGDKIEELERHIFESSTSSNETPNKIQALKQDVLKIRRAIFPLREVINRLDKTDINFLEIKTHDYLKDLHDHIIQVCESIDLYREMVWSLMDMYMTIINNKMNEVMKVLTIMASIFIPLTFIAGIYGMNFDHMPELHTKNGYYILLGAMAVIFVLMLFYFRRKKWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIX4</accession>
    <name>A0A5C6ZIX4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="174"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="202"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="263"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="289"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="312"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="335"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="363"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="398"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="587" mass="67418" checksum="75730D7E48E4D0F6" modified="2019-11-13" version="1">MTSNLYLTNNKFKITLGIIILIQILLAFQGFDMVDDGFVLTFYQQIFNHPETVEYNFMYWFSGIVGGLWYQLYPEGGVFWFRMLGLIVNTSTFILSYQLLKKHVPKTYLLFALVMVLFQNNYGFTTFYHNHLTALLCLLTVFTLLKAIEKESVILYVLTGIIIIFNTFTRLPNLVLLSLLLVIPFFFLLSKKPFVSKSIRPIALVVLGCLLGLLSVYGILMATGQFQVMKSMFVMLFDLGNTDGSAHNVGDILRSQVFNYKQIARTFFELAFILGLAVLIKHFLPKRRVLAVVLSVFFVSLLIVWYEKQGIGAAYTLSYIGCIWTLFSRKKAIHLRLIALCSFLILFTLTLGTTGGMKNSGYMAIWLGLPLFFLVLPEIFGCIQCILNKIFSTEKFKVSKPVFSLLWCFIIAFLLLKTYHISNEAYFDEGSRLEKTYAINNKFAKGIYTKQRRAEIVNDLLAGLSNYVQPNDYLFSYDHIPMIHFLTETRPYPYNSWVGIYDENSFRKKIAKAEQEISVLPIVVQQKFNTIHRFAEPDPNYMDASSANTILHAAASVSTMNSFLERHNYQIVWSNAYFNIYKAKQGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIX7</accession>
    <name>A0A5C6ZIX7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_05510</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="130" mass="14736" checksum="18012D95976B9344" modified="2019-11-13" version="1">MKNLKFIGIFLLFGICFSCSDNDELTQEQEEQNLIQMFSEIESSARSVNCNDSSEWDFTSYGSKNCGGFGPVGFIAYSINIDTQLFLEKIEKHKRAQQRFNEKWEIISDCSLASTPISIICEDGSPVFAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ14</accession>
    <name>A0A5C6ZJ14_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cell shape-determining protein MreB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">mreB</name>
        <name evidence="3" type="ORF">ESY86_05790</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Forms polymers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="2">Membrane-associated.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the FtsA/MreB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000902">
        <property type="term" value="P:cell morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd10225">
        <property type="entry name" value="MreB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02207">
        <property type="entry name" value="MreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004753">
        <property type="entry name" value="MreB"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01652">
        <property type="entry name" value="SHAPEPROTEIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00904">
        <property type="entry name" value="mreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0133">Cell shape</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="17"/>
            <end position="19"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="163"/>
            <end position="165"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="211"/>
            <end position="214"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="342" mass="37360" checksum="F7E26CB5F47C5B73" modified="2019-11-13" version="1">MGFFDFLTEEIAIDLGTANTLIIHNDKVVVDSPSIVARDRISGKIIAVGMEANMMQGKTHENIKTIRPLKDGVIADFDASEQMISMFIKNIPALKKKLFTPALRMVVCIPSGITEVEMRAVKESCERVNGKEVYLIHEPMAAAIGIGIDIMQPKGNMIVDIGGGTTEIAVIALGGIVCDKSVKVAGDVFTNDIIYYMRTQHNLYVGDRTAEKIKIQIGAATEDLDLPPEEMSVQGRDLLTGKPKQVQISYREIAKALDKSILRIEDSVMETLSQTPPELAADIYNTGIYLAGGGSMLRGLDKRLSQKTDLPVYIAEDPLRAVVRGTGIALKNLARFKSILIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ26</accession>
    <name>A0A5C6ZJ26_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_06860</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="66"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="101"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="306"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="265"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="346" mass="37026" checksum="B353078CD1F31790" modified="2019-11-13" version="1">MKNVSTHLNYAKNRISRISWGGVLAGALTAITISFLLNLLGLGLGLNSIDPLTEAQPFSGLGIGTIVWWVLSNLAALFVGGLIAARAAGLPSGADGGIHGFLAWGAYLLVSIFIVTSITGSIFSGMGSLVSSVFGGDSAKEVVVNMKKAQDATQSGTDTTIQGVKDEIYQILETAQEYNLIPEGSKSEVKAEYNEAKAETQKAIKELDLKDALTDFVNDVSVNLDRNGDLDISVEGNQEYIDKETLKDYLTENTALSDEEINGVITKWETKIDKAITEIEETYAEAKEQALKASEEVSDALGTASIYLFFMLLLGALAAFFGGATGAPKLGVIEERNQDLQDEQHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ30</accession>
    <name>A0A5C6ZJ30_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Tail-specific protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_09325</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the peptidase S41A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07560">
        <property type="entry name" value="Peptidase_S41_CPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004447">
        <property type="entry name" value="Peptidase_S41A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020992">
        <property type="entry name" value="Tail_Prtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040573">
        <property type="entry name" value="TSP_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11818">
        <property type="entry name" value="DUF3340"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00595">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17804">
        <property type="entry name" value="TSP_NTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00245">
        <property type="entry name" value="TSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00225">
        <property type="entry name" value="prc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0720">Serine protease</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022728160" evidence="5">
        <location>
            <begin position="23"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="6">
        <location>
            <begin position="273"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="178"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="178"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="205"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD89306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="735" mass="84811" checksum="E45764C228C3A8BD" modified="2019-11-13" version="1">MKRNYKLLLVGLLLAFASCSFTTKKFQDPNKDKLLIQLIKYVLEQGHFSPQDINDDFSKNVYNDYLKQLDPFKRYFYASDIKEFDAYKDKIDDQINDYDVSFFNITHERLLKRIEESKAIYKDVLSRPFDFSMDEDFSTDYEKLSYVSSKKEMTNRWRQQLKFSTIANYDDLLSQGKNAATKKQNQQTQNDLNGAIEESMDNTLAETSSEERKSDAEYEKEARETTERSLDELYDFIDDRQRKDWFGVYINAIVEEFDPHTYYFAPEDKDRFDVAMSGNFEGIGARLQKKMDAITVTEIISGGPAWRDNELEVGDQIMKVKQENEAESVNIVGMRLEDAIKFIKGPKGTVVMLTLKRVDGTIEDITITRDVVELEETYAKSSTVDKDNRTFGVINLPKFYVDFDDYKKRNAASDIKQEIERLKQAGVEGIVLDLRNNGGGSLQTVVDMGGLFIEEGPIVQVKTAGEPKEVLNDKDKSIVWEGPLVILVNELSASASEILAAAMQDYKRAIIIGSKQTYGKGTVQNVLDLNRMVKQNDNGDMGALKFTTQKFYRINGGSTQLEGVKSDVVVPDRYSYINIGEKDQENPLPWDKIDAVTFQPWENYYDYDSTIAKSKERMKNNEQLKLIDANAQWVKKIRDREIYSLNYYTYSSEMDVNEEESKRFEQISDYNTNLTFKSLPYENELMIQDSILKEKRDRWHSSLSSDVYMEEAINVLNDINSNYKIKNNVANAVKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ73</accession>
    <name>A0A5C6ZJ73_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SRPBCC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045736">
        <property type="entry name" value="START_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19569">
        <property type="entry name" value="START_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="START_2" evidence="1">
        <location>
            <begin position="1"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF19569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="130" mass="15219" checksum="EA6129FC101C248E" modified="2019-11-13" version="1">MEEKVKIEMEFVVHASPQLLYQYISTPSGLSEWFADNVNSRGEFFTFIWDGSEEKAKLLSKKSGERIRFRWMVDEEEGDAYYFEIRIQVDEITKDVSIIVTDHVEEDEVEEAKMLWDNQISDLKQVLGSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJH4</accession>
    <name>A0A5C6ZJH4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carotenoid biosynthesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07035</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007354">
        <property type="entry name" value="CruF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39419">
        <property type="entry name" value="PTHR39419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04240">
        <property type="entry name" value="Caroten_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="170"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="203"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="255" mass="28273" checksum="EC19BBBA8DA1F592" modified="2019-11-13" version="1">MDIKKIILVTLSILFFIIGFMMSSVPSKQFVETGSIIAVGIISMPAFYGMWKIYGRRGIAAIMALGVFALIIESIGIHTGFPYSPFEYTMPFGYKLLGTTPWTVFIAWSPLVFGAWLLAQTWFEHHWARYLAYLGILVGTDMILDPGAVARGLWEYTNGGLWFDVPLQNFIGWMISGTIAYLILKLVLKPVIVKGSVALSKHLWIGTLSLLVSIFLWTGVDAGYGLWAPMIVGIIIGTIIIKALFKTYATTSKNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJN3</accession>
    <name>A0A5C6ZJN3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">SDR family oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_05335</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="267" mass="28434" checksum="E30A37C2EF27A8C0" modified="2019-11-13" version="1">MMKLQNKVAAIFAANGAIAREVAIEMAKEGAIVYVSGRNLSEVESLSAEIIANGDFAKPFQVDATNENEIENFIKQIVEEEGKLDIVFNGIGIRAKDGGYGQPSTQIPFETFMKPIQVHLGSQFLTSRISAKHMQQTESKGTILLLTASLSRLKSPFMSGITAACAGIEGLTRTFATEFGMSGIKVICINPTAMPETRTIIETTIENAKTIGIPAEVMAEQMTNGGLLKKSLTTKDTGKVAAFLVSDAGAALNSHIVDVDFGTASVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJY6</accession>
    <name>A0A5C6ZJY6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TolC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_04970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="416" mass="46826" checksum="DBCA511631CBE337" modified="2019-11-13" version="1">MKRFTFILIVFASVPMLGQQNISLEECYELATTNYPLAKQSQLFEAQSKLDKAIISNSKLPQFSVDAQATYQSDVIEIPIPNTNIEALNNDQYRATLSVNQLIYNAGATDASIMVRAAQLKTQQKQVEVNLYQLKQNINQLYFSILLSQETQLLLAAKKELLQVKLSEVQSGIKYGVLLPTSDKVLEAELLKLHQQFSEVESNKASLIETLSSIIGKSLADYTSFENPLLENELNTNLNRPELQLFQLKKNEIESNEALIAKQNAPKLLGFATGGYGNPGLNMLDNSFQPFYTVGIKLNWNVFDWNSNKKQRESLSITKDIVDTETELFKLNTGIELNQQQQEIAKIESFITSDLEIIDLRKEVLKSADSQLKNGVITASAYITELTNLYEDENTLVTHKIQLQLAKANYNVIKGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKC8</accession>
    <name>A0A5C6ZKC8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">4'-phosphopantetheinyl transferase superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_09875</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008897">
        <property type="term" value="F:holo-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008278">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01648">
        <property type="entry name" value="ACPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="SSF56214"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="219"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="ACPS" evidence="3">
        <location>
            <begin position="87"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="244" mass="27060" checksum="AB1A78BFCD221072" modified="2019-11-13" version="1">MEEKIKSLYTKLSNQSIENSDSVISTDVFSSVLLDRFTAELSKLGVTWDKEPTSINMLIGNAARPVVATSVSMENTVKKENSKTLAIGTDIQKLDKFPKVKDFWEEPFYTDTFSATEIGYCLKKSNPIESFAGIFAAKEAVFKATGIARQDVIINHTDKGMPVCDYASISISHDGDYAVATAFIGNQTIVSVSDDENRSIETIKPSVANIPKQTSHSNRLLWSLCFILIVGYIIYKEFLEALIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKE3</accession>
    <name>A0A5C6ZKE3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_01715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022997778" evidence="1">
        <location>
            <begin position="21"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="246" mass="26587" checksum="11D9BFE3F8F502EB" modified="2019-11-13" version="1">MRKYFRIFMFICLVALFTNCETDDATQTELSNYVGFEIMNPMRVTVENNATQSFEVKVYASETSSADRTYGLAIDGGSSLATSYTVPASVTIPGGSNVGTFSVSITDDDNLQFVAQSLVINFEKEVGLDFSDAFELRVTESCLETIVTFSLTLDIYPDETRWELYDLSGAPTIIESFGPFNRPADNGQTVSYDFCLASGDYGIVVYDSYGDGIGDAGSDYNISVGGTVLVSGVVAGDSGQSEFTID</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKQ2</accession>
    <name>A0A5C6ZKQ2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">SusC/RagA family TonB-linked outer membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_02845</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023996">
        <property type="entry name" value="TonB-dep_OMP_SusC/RagA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023997">
        <property type="entry name" value="TonB-dep_OMP_SusC/RagA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04056">
        <property type="entry name" value="OMP_RagA_SusC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04057">
        <property type="entry name" value="SusC_RagA_signa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022748831" evidence="5">
        <location>
            <begin position="22"/>
            <end position="965"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="7">
        <location>
            <begin position="114"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="6">
        <location>
            <begin position="383"/>
            <end position="964"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD90911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="965" mass="106200" checksum="4B2958B01DED100E" modified="2019-11-13" version="1">MKTFLNGLFLLVFLMPALLFAQTQVSGTVTDEANAMPLPGVNIIIKGTSTGASTDFDGLYSITVTEGQVLVFSYLGYETKEITFTNGSQLNVALKPDAGKLDEIVLIGYGSTTKQDATGAIEKVSDEEFNRGAIVAPQQLIAGKAAGVRVTTGGGAAGEGGEIRIRGGASLSASNSPLIVIDGLPIDQSGAAQGSANALNAINPADIEDFVVLKDASATAIYGSRASNGVILITTKKGSVNQPLKIEYGLQISTRRVANTIDVLDADQYRDLASNPGFDSSSLGNANTDWQDEIYTTGVGAIHNITVSKGYERSNFRINFNHASQEGPLQDLYERNGINASFVQRLLDNDLKLTLVTKAVQDEFSYANRGAIGAATRFDPTQSVLDNNGNFTQYGSDANLAPANPLFLLEEYDNRQTIQRLISNFNLDYNFWFLRDLTLTVNAGIDYAENDGHRFEAGNPNNPDAFALNEISSGQNRNTSLDFYLNYKKEIESINTKMDITAGHAFQEFYRSSFFDRSTNISISQRDINRNALESYFARGSFDIADKYLISANIRRDGSSRFSEDNRIGYFPGVSVGWKVMNESFMENSLFSNLKLRAGWGVQGQQEIGPNYGYQGLYTPSRNQAANIQFGTQPNGDPRFISTIRPEPYDENLKWEETTQYNVAVDFGFFNNRLSGSIDAYYRETEDLLSLVPVPAGANLTDILLTNVGQVTSKGLEISLNGVIMKEEDFGWDTNFNITFQEQEITSLSLNDDPDYFIPTGGINGGVGNNIQILKPGFDPSTFFVFRQVYDNDGNAIEGAYVDVNGDNIITEADRQAYKKATPDAFIGFTNNFRYKNLDLNFTFRGNFGNYVYNNSASENGNLNNVLNQPGYQANAHASLLDTGFGNQNLFSDLYIQRADFIRLDNISFGYTIPFEKIIFRASLTANNVFVITEYDGLDPEISNGIENNFYPRTRDIVLGLNFTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKT4</accession>
    <name>A0A5C6ZKT4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Prenyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_03475</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="111"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="140"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="171"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="223"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="250"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="282"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="303" mass="34208" checksum="BD5ECBE0A9E4DDB4" modified="2019-11-13" version="1">MHLLNLIRYKNLLLIILAQVLIKYALLEPFAVLTALDGFHFSLLVLATLCLAAAGNVINDIYDVDTDRVNRPNKLIVGGHISEKIAYNLFFALNIIGVVLGFYLSNHIGKPPFFSIFVLISVSLYVYASFLKRTILFGNLLISALVGISLLIVGIFDVIPAMFPQNRQTQITFFNLIFDYAVFAFMINLLREIIKDIEDVDGDYKAGMNTLPIALGRERAKKIAFAVSMLPIAAVIYYVVTYLYHQQLVIAYFLILIVAPLIYATIKIFGAKQKQHYQHISLIYKLVMLFGVLSMLLYPFVLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKW1</accession>
    <name>A0A5C6ZKW1_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">CRISPR-associated endoribonuclease Cas2</fullName>
            <ecNumber evidence="9">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9 10" type="primary">cas2</name>
        <name evidence="10" type="ORF">ESY86_02650</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer, forms a heterotetramer with a Cas1 homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="9"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043571">
        <property type="term" value="P:maintenance of CRISPR repeat elements"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01471">
        <property type="entry name" value="Cas2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021127">
        <property type="entry name" value="CRISPR_associated_Cas2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019199">
        <property type="entry name" value="Virulence_VapD/CRISPR_Cas2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09827">
        <property type="entry name" value="CRISPR_Cas2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01573">
        <property type="entry name" value="cas2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="5 9 10" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 9" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD90877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="109" mass="12787" checksum="43D188E99328A4F6" modified="2019-11-13" version="1">MELNAYRIMWLFVFFDLPTNTAKDRRNAAGFRKNLLKDGFTMMQYSVYMRHCASSESADVHEKRIKRLLPPLGKVSVLRITDKQFGNIMNFWGRSEVPNEPQPSQLELF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKZ4</accession>
    <name>A0A5C6ZKZ4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_04695</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="74"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="275" mass="31193" checksum="203C201D02E3E5FE" modified="2019-11-13" version="1">MRRFLAKSIGFFTNVWSFVSAEAAGKIALKLFSSPRRVKIKELQKDFLDTAFIEDVDYEHLSIKTYRWLGKKETVILAHGWESNAFRWKNLIIKLRTLDYNIIALDAPAHGYSSGNKFNAILYAECINVVAQRFGAQIIVGHSVGGMSTAYFLSKYKMPSVKKIVLLGAPSNFEGVFGRYVEMMGYNKRVAKAINQLIFEQFSYMPEHFNAAKFAEGVTAEGLVIHDKFDKIIPYSDAEDFQNFYKTSKLITTEGLGHGLKTDEVNAHILEFITQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL09</accession>
    <name>A0A5C6ZL09_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_03850</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="127" mass="14575" checksum="A80911DBAE95067C" modified="2019-11-13" version="1">MNVLDKTNILNTIANKQAELRSTHKKLSLPLINRLYKKMARGIKFDAIKVCDSLIIDGHHRYISSLLADVDLETLKSPKTSATIAYDWTEVDFVAEDWDTEDDILHWNHLDAQSNILALEELLELTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL23</accession>
    <name>A0A5C6ZL23_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidophosphoribosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08115</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13537">
        <property type="entry name" value="GATase_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="1">
        <location>
            <begin position="9"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="632" mass="71801" checksum="A76AEAA7C95E5F43" modified="2019-11-13" version="1">MSDALKHECGIALIRLKKPLEFYKEKYGSAFYGVNKMYLMMEKQHNRGQDGAGFASIKLDTKPGERYISRVRSIAQQPIQDIFDQINERINEEFAAHPEYQDDVALQKRHIPYIGEVLLGHVRYGTFGKNSVESVHPFLRQNNWMHRNLIVAGNFNMTNVNELFDGLIALGQHPKEKADTITVMEKIGHFLDDAVSKIYKKLKKEGYSKSECSPLIAERLNVAKILKKSSKNWDGGFAMAGLLGHGDSFVLRDPAGIRPVYYYEDDEIVAVASERPVIQTVFNVNFEDVKELDPGHAIITEKSGVTTIKQIMKPLERKACSFERIYFSRGSDAEIYQERKTLGKLLMPKVLEAIDNDTKNTVFSYIPNTAETSFFGMIETVEQHLNEQKTKAILNGNGQLTSAQVTEILSERPRIEKIAIKDVKLRTFITEDSSRDDLVAHVYDVTYGVIKPTDNLVIIDDSIVRGTTLKKSIIKMVDRLNPKQIIVVSSAPQIRYPDCYGIDMANLESLIAFRAMLELLKENNKYHLVEEVYEKCKLQLTIADNEVRNYVKDLYSEFTADAISDKIAELISEDTVKAKVKTIFQPIANLHKACPKNLGDWYFTGNYPTAGGNRVVNRAFINFYEGNNERAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL53</accession>
    <name>A0A5C6ZL53_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03185</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002741">
        <property type="entry name" value="MppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SBP_bac_5" evidence="1">
        <location>
            <begin position="76"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="540" mass="61461" checksum="A55F2A744B3AB941" modified="2019-11-13" version="1">MNFSSKYLRLSSIYIATLGLLCCETDTKQNKDHLVFRYNEHKNIGSLDPAFAKDNADVWATNQLFNGLVQMDDNLEVQPCIAKSWTISEDGLTYRFNLRKDVYFHKDALFGRDSTRAVVAADFDYSLSRLTNKQLASPGSFTMNKVEGFEVLNDSVFQIKLKQAFPAFLGLLTMKYCSVVPREVVEHYNNTFRSHPIGTGPFKFKRWEENLKLVFRRNEHYFENDSVGNQLPYLEAVAITFLPDKQSEFLQFAQGNIDFVSGLDASYKDEILTASGELRAAYSEEVNMIRAPYLNTEYLAFYMEAEIPEIQSLLLRKAINYGFDKQKMMTYLRNGIGIPATGGFIPKGLPGYDASIGYSFKPDKARQLVAEFKAETGITRPEVTLTTISNYLSFCEYIQRELQKVGIAVNVDVIPAATLKEAKANGNLDFFRASWVADYPDAENYLSLYYSKNFAPNGPNYSHYKNNQFDSWFQDAFTETDAKKRTALYTKMDSLVMSSAPVVPLFYDEVVRFTRKEVSGLGINATNLLDLRRVKKSESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL57</accession>
    <name>A0A5C6ZL57_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Mechanosensitive ion channel family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_04105</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045275">
        <property type="entry name" value="MscS_archaea/bacteria_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011066">
        <property type="entry name" value="MscS_channel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30221">
        <property type="entry name" value="PTHR30221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82689">
        <property type="entry name" value="SSF82689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="58"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="88"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD90559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="376" mass="42386" checksum="24CB57CD82AF0B0C" modified="2019-11-13" version="1">MEQFLETYKPHLITAVVIIGAYLMLRLLTNLLHKWLLKKEFQKIPDASRRPINLVKRVLNVLWLILGCIALSSIFVDREKDAALTAYFKLAGYLGFLAVLTIVAATAVNVWFKVKIKEKIENEFDPTSYKFLRYVVVFIICFVGILFGLLAFPSLRGVAQTALGGAGVIALIAGVASQEALSNLVGGVFIISFKPFKIGDIVKVTDTMVGRVTDITLRHTVIRNFENKMIVIPNAIINKEKLINYDLGELKCCEHVEIEIAFDSDIDLAKKILQNECEKHPLIYDNRTLLEKKDGKAMVRTALIKLNDSSMTIRAWAWSENFTNSFALKCDVFESVVKRFAKEGVEIPYPYRSLVFKQTLANEGEDEQAETKAQTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLB3</accession>
    <name>A0A5C6ZLB3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DUF3526 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_05455</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032688">
        <property type="entry name" value="ABC2_membrane_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021913">
        <property type="entry name" value="DUF3526"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12679">
        <property type="entry name" value="ABC2_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12040">
        <property type="entry name" value="DUF3526"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="17"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="130"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="209"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="441"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD90187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="469" mass="53613" checksum="2B3DFBFD927834AA" modified="2019-11-13" version="1">MFQIIKNEWRFLLRSRIFLGISIGFIAILIVSVFLGNYQTQKQDQTQTNAKEHVRQQWVSIDEMNPHSAAHYGTYVFKPANLLSSLDEGVNSVTGNVLRVEGHVQNEIVHSEASQMQVVSRFGKLKSSLLLQYIVPLLLIFLAFNSVSSEKQSGRLKLLILQGAKPIQLILSKTFSVWLYGLLLLLFVIVVYGILNLQSLTSEILFRTGLFFLSYALYYFIISGLTVFFSARWQNATLALTSMLGIWILWTIFLPNVLMSSVEKWHQLPSRNEFQTAMDEDRSKGLDGHNPTDERTKALEEKVLKEYKVDSLSQLPINFDGLLMQADEDYGNKVWDKHFGNNRNVLQEQKQSFQLGGIVNPFISLQNTSMGFMASDNVHHQEFLLQVENYRRVFIKMLNDEHAFGGSKTGNWGKNADNAFFRSVPDFDYKPTQLSVVFSNYMLDLALLAFWSVLVFALILFGTKKIEIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLD2</accession>
    <name>A0A5C6ZLD2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta fold hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03615</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003718">
        <property type="entry name" value="OsmC/Ohr_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036102">
        <property type="entry name" value="OsmC/Ohrsf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02566">
        <property type="entry name" value="OsmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82784">
        <property type="entry name" value="SSF82784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydrolase_4" evidence="1">
        <location>
            <begin position="42"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="405" mass="44492" checksum="93834D77D9220736" modified="2019-11-13" version="1">MDQNSLTIKNKNGHQLNATLELPANGKPAAYAIFAHCFSCNSDYKAVRNISRALNNQGLGVIRFDFTGLGQSEGEFANSHFSANVSDLLAVNDFVTANYKAASLLVGHSLGGAAVIVAASKLDNIKAVATIGAPSHIDHVIHHFSHAIEEVEEKGDVEVSIGGRPFKINQEFVEDFSKTDLLAITKSLRKPILILHSPTDKIVGVDNAQELYQHAMHPKSFISLDAANHLLTNNADSLYVGNMIGNWVKHYLDSEKNQMLDIEGEQLVAHLNLLEDNFTTTIQTETHSFLADEPESVKGDDLGPSPYDLLSSALASCTAMTLKLYAQRKKWDLQEVFVYITYSKKHANDLMGQGTTGSKIDHLQKKLKFIGDLDASQKERLKEIASKCPVHKTLITETLIETEVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLH9</accession>
    <name>A0A5C6ZLH9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05835</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="40"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="259" mass="30010" checksum="0193A051CBC19ED6" modified="2019-11-13" version="1">MAKKAEASVEDRLRALYDLQLIDSRIDEIRNLRGELPLEVQDLEDEVEGLNTRLEKMGTSLELIDNDIKSKKNLIEEANALIKKYSEQQKNVRNNREYNSLTKEVEFQELEIQLADKHIKEFRVQIEQKKEVVTETKDRLKERKSHLKHKRGELDAILSETQKEEDALLGKSEDFQKKLDERLVNAYMRIRNNVKNGLAVVPIERGASGGSFFTIPPQVQVEIASRKKVITDEHSGRILVDAELAEQEQEKMKKMFAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLI7</accession>
    <name>A0A5C6ZLI7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="1">
        <location>
            <begin position="26"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="380" mass="43244" checksum="20ECCFAE80AF387E" modified="2019-11-13" version="1">MNISAKLNTTEASIFSVMSNLANQHDAINLSQGFPDFKCDQNLIDAVSFAMNAGHNQYAPMPGLMDLRVAIAKKFDLLYGTSYHPESEITITSGATQAIYTIISTFVKQDDEVLIFKPAYDCYEPSIKINGGKPISMALKAPDYKVYWDEVKKSINLKTKMIIINTPHNPSGTLMSKSDMLKLQELTNGTDIIILSDEVYEHIVFDDEQHQSVCRFPELKKRSFITASFGKTFHVTGWKTGYCCAPKALMQAFRNVHQFNVFSVNHPMQKGIADYMKDPNRYLELPEFYQQKRDLFLELIKDSRFKFSPSKGTYYQLLDFTDITTENDLEFAKRLTTEKGIASIPLSPFNDNARDDKVLRFCFAKTEDTLKKAADILNRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLM7</accession>
    <name>A0A5C6ZLM7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">UPF0175 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_02155</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0175 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005368">
        <property type="entry name" value="UPF0175"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03683">
        <property type="entry name" value="UPF0175"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="86" mass="9956" checksum="E876916A8E635B0E" modified="2019-11-13" version="1">METHNISIDIPNDILLALNETANDLKKRIKLTLAIELYKKQKLTIGKAAQLSEMSRLEFETELSNQKISISNLRKEDVFRDLEKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLM9</accession>
    <name>A0A5C6ZLM9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ESY86_04245</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="66"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="155"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="247"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="30"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="346"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="379"/>
            <end position="386"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD90585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="589" mass="66573" checksum="5F7A708ECED06160" modified="2019-11-13" version="1">MDTPKKKKAFDLSLFKRLLLYIQPYKSVFFVALICVIGLAVFGALRPLVLQKAIDEHIAIKEYDGFMLLIIAMAVLLVLEVVSQLLFIYYANWLGQSVVKDIRVKLYDHVLRFKMKYYDNSSVGVLITRTVTDMERIADIFGEGLFMIFSDLLKMLVVGGMMCFINWKLSLIAFITMPIVLFATKIFQKYMKRAFEEVRNEVSNLNSFVQERITGMKILQLFTREDTEYKNFKAINERHKKGWLKTVWYNSVFFPIADLLSSITLGAIIWVGGLMVVMGNTATEGELFAFIMYVPMLFRPLNQIANKFNTLQMGMVAADRVFRVLDTTSQIDDAGTEIASEFKGDITFKDVHFSYVADELVLRGISLEVKAGQTIAIVGATGAGKSTIINLLNRFYDIQRGSICIDGKDIKSLTLKSLRAQIAVVLQDVFLFADTILNNITLKNPNITEAEVIQAAKDIGIHSFIMSLPNGYKYNVKERGVMLSSGQRQLISFLRAYVTNPSILVLDEATSSVDSYSEQLIQDATEKITKDRTSIVIAHRLATVQNADQIIVMDAGKIVEKGTHQELLKLENGYYRNLYEVQFLKAEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLP9</accession>
    <name>A0A5C6ZLP9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GNAT family N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_01095</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="6"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="163" mass="18341" checksum="F53B1FF30574C5F5" modified="2019-11-13" version="1">MSQESIVIREIREADNAQLEQVIKGCFPEFEIPLKGTAYEDAETPKMFESYQGEKEVYYVVVKGDQVLGGAGIKKLKNYEGNVCELQKMYFSPEVRGRGFGKQLIIQCMEAAAAFGYAQCYLESAVQLKAAIHVYEQAGFKQRTEPLGNTGHYSCGVWMEKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLT2</accession>
    <name>A0A5C6ZLT2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF4230 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_01970</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025324">
        <property type="entry name" value="DUF4230"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14014">
        <property type="entry name" value="DUF4230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="211" mass="24433" checksum="88DD646780D20ADA" modified="2019-11-13" version="1">MRKIITGILLALVVLLTIKYCDDKNEDRIVLKEHSALIQEQIKNVGKLVVTEGHFSEVFSYKNSKAIFGNLFEVEKKALVVVNADVTVAYDLSKIEYEIDEATKTLRIISIPKEEIKISPDFEYYDVQADYLNQFQAKDYNNIKESVKKSLMKKINASDLKNNAENRLISELSKFYILTNSLGWTLEYNKQQVKSLEEVERFQNLKLLKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLW9</accession>
    <name>A0A5C6ZLW9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_02195</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="515" mass="60949" checksum="1BB9E2A533109049" modified="2019-11-13" version="1">MTKDQKDNLFLLVKSLTKSEKRQFKLYVGRLDVNQDSKFLNLFNVLDKASVYDETAILKTKIVKKQQLANVKAHLYKQILISLKLNPSHQNIRSQIREQLDFASILYHKGLYKQSLKILDKSKEVALQHEEKNLAYEIVELEKIIESQYITRSISTRADELAVQAKEISSLNVIASKLSNLSLQLYSVILKTGYVKNEDESRMVTSYFKERLPKYNIQELGFREKLWLYNANLWYSFLMQDFLNCYKYASKWVELFNEHPNMLRLNPVFLLKGHNYLLEALFYVQNKEKFQNALLKFQIITSEKSFPKDENVQALTFLYLNINSINLYFIDGSFDDGLKIIPKIEKELQNFKDRLDEHHLMIFYYKFASMHFGAGNNKECIFYLDKIISNKSLLMREDLQCFARVLNLVAHYEAGLDYHIETLLRSTYKFLLKINDLYEVQKEMIKFIRGLQDIYPQDIKKAFIGLHATLKTYEDHPYERRAFLYLDIISWLESKIQNKPVGQIIREKFHAKNKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLY5</accession>
    <name>A0A5C6ZLY5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_07005</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012318">
        <property type="entry name" value="HTH_CRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13545">
        <property type="entry name" value="HTH_Crp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00419">
        <property type="entry name" value="HTH_CRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51063">
        <property type="entry name" value="HTH_CRP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="4"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="3">
        <location>
            <begin position="161"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="HTH crp-type" evidence="5">
        <location>
            <begin position="276"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD89940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="351" mass="39910" checksum="0E4A9334C2935F60" modified="2019-11-13" version="1">MTKKVLLIEDDAVLRENTAELLELSNYEVLVAANGRLGLEKARQQKPDIIICDIMMPELDGYAVLELLSKEEHTKFIPFIFLSAKTERNDVRKGMELGADDYITKPFSEAELINAIESRLAKMAILREGLTQFETPNAETGSEIRTINDLKNFFIQNGEAFNHRQGQIIYREGQNSNYIYLLNKGVVKCHKLDEQGKELTTALHKEQELFGYTSFIQNIPYQETSTAIEAAQLVGISKDQLKFVLDHNPKITLELVQMLTEDLQGVKNQLLQMAYSSVKRKTATTLLKFAEKLNRKPEDPIIISRNDLASVAGIATETLIRTMSNFKKEGLIEIEGRNVRILDLKKLQEIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM12</accession>
    <name>A0A5C6ZM12_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF885 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_01510</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010281">
        <property type="entry name" value="DUF885"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33361">
        <property type="entry name" value="PTHR33361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05960">
        <property type="entry name" value="DUF885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023068696" evidence="1">
        <location>
            <begin position="19"/>
            <end position="599"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="599" mass="67957" checksum="92C9734090FFE9E6" modified="2019-11-13" version="1">MKHIFIACLVLLSLSACKNDKTETAEEPQKTNIQENMEFSNALDQYYEDGLQLDPLSATAAGDHRFNDQMPNYLAEDYKAKLQSYYSGYKSKINAFDDADLSESQQMSKAILNWECDINLEGLAFDQDLTPINQMWTLQLGIGQLASGAGAQPFKTVEDYQNWLKRLDGYLAWMASAEDKMKQGILSNQVLPKSLILKVLPQLEALTTNNLNAHLFYAPVLNFPKDFSEADKKQLTKAYQDKVKTEIIPAYTKLHDFMAGEYLEAGRISSGLADTPDGNAYYKHQIKRYTTTNMTADEIHELGLQEVARILTEMEKVKQQVGFEGDIMSFFDAVRNTPELMPYKTPAEIIDHFNKIHQIMQPHLEKMFDLKPNTPFEVRQTEAFREASASAEYNPGSLDGTRPGIFYVPIPDASTYNVFSSESLFLHEAIPGHHYQIALQQENKDLPKFRKTLWYSAYGEGWALYSESLGKELGLYTDPYQYFGMLSAEMHRAIRLVVDTGIHAKGWSRERAIKYSMQNEAESIAGITSEIERYMANGGQALSYKIGQLKILELRAKAEKTLGKNFNIAKFHNQVLMNGCVPLALLEDNINAWIDSERE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMF1</accession>
    <name>A0A5C6ZMF1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methylmalonyl-CoA mutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_00585</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016866">
        <property type="term" value="F:intramolecular transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016176">
        <property type="entry name" value="Cbl-dep_enz_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006099">
        <property type="entry name" value="MeMalonylCoA_mutase_a/b_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01642">
        <property type="entry name" value="MM_CoA_mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51703">
        <property type="entry name" value="SSF51703"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="METMALONYL_COA_MUTASE" evidence="2">
        <location>
            <begin position="143"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="380"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="383"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD91122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="454" mass="51570" checksum="4570D60FBD22F14D" modified="2019-11-13" version="1">MTKPLFEQFKAVSAKQWKQKIQADLKGADYNDTLIWHSNEGINVKPFYHADDFEHLPNTSEARASQFKICQTIFVANVQMSNKKALDAIERGAESIKFIIPAEDISIEQLLQNITLSSIPIYFELQFLSSDYVKNIPSENTVILNDIIGRLTSTGNWFKTLNEDFSKFETIVKQTASFSVDASIYQNAGANMTQQLAYCLAHAAEYLQVLDHKLTEAEKAKLEVHFTVAVGSNYFFEIAKLRALRTLWRSLASEFNVNPKCEIFAIPTKRNKTLYDYNTNMLRTTTECMSAILGAANTVCNLAYDAIYHKDNEFGERIARNQLLILKNESYFDKVDNPADGAYYIETLTTELATKALEIFKDIEANGGFLAQLKEGTIQRKSKESAQQEQQQFDQGKITLLGSNKHPNPEDRMSDDIELYPFVKTNPVKTLIEPIIAKRLAETIEKERLKAETE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMI5</accession>
    <name>A0A5C6ZMI5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">30S ribosomal protein S6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsF</name>
        <name evidence="6" type="ORF">ESY86_00105</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Binds together with S18 to 16S ribosomal RNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the bacterial ribosomal protein bS6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00473">
        <property type="entry name" value="bS6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00360">
        <property type="entry name" value="Ribosomal_S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000529">
        <property type="entry name" value="Ribosomal_S6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020814">
        <property type="entry name" value="Ribosomal_S6_plastid/chlpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035980">
        <property type="entry name" value="Ribosomal_S6_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014717">
        <property type="entry name" value="Transl_elong_EF1B/ribosomal_S6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21011">
        <property type="entry name" value="PTHR21011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01250">
        <property type="entry name" value="Ribosomal_S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54995">
        <property type="entry name" value="SSF54995"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00166">
        <property type="entry name" value="S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD91039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="112" mass="13438" checksum="59E24D38D5231CD4" modified="2019-11-13" version="1">MNHYETVFILNPVLSDDQVKETVQKYEDFLVSRGAKMVAKEDWGLKKLAYPIQNKKSGFYHLFEYTVDGEHINPLEVEFRRDERFMRYLTVTLDKHAIAWAEKRRKRDQQKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMI7</accession>
    <name>A0A5C6ZMI7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DNA mismatch repair protein MutS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_00815</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036063">
        <property type="entry name" value="Smr_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="181" mass="20930" checksum="B542CC8BBF6A1530" modified="2019-11-13" version="1">MEFKIGDLVSVLDDNISGRIVNIHADEISIETEDGFEMNFTKKELIKDKTLDSDLFKHSDMDTVLQEKEQSHKKKSVGVKPKERNLPAMEVDLHIHQLTTSHKNMSNHEMLNLQLDTARHKLEFAIKKRIQKLVFIHGVGEGVLKMELDYLFGRYENVKFYAADYQKYGLGATEVYIFQNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMJ2</accession>
    <name>A0A5C6ZMJ2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ATP-binding cassette domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_04465</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="5"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="277"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD90627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="306" mass="34132" checksum="697857F9B634844B" modified="2019-11-13" version="1">MESILSINNLTKKFGYLTAVKDLTFDIKKGNVYGILGPNGSGKSTTLGIVLNVVNKTSGSFNWFDGKVSTHNALKKVGAIIERPNFYPYMTAAQNLKLVCRIKGVEPAKIEEKLELVGLLDRKNHKFSTYSLGMKQRLAIASALLNDPEILILDEPTNGLDPQGIHQIRQIIKEIAATGTTILLASHMLDEVEKVCSHVVVLRKGEKLYSGRVDEMIASHGFFELKSQQHEALLKVLEEDPIFGTISVENELIKVILLEPMDASSFNRLMFDKGIVLSHLVKRKESLEEQFLQLTDNNNDQKLQSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMK6</accession>
    <name>A0A5C6ZMK6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">3-hydroxybutyryl-CoA dehydrogenase</fullName>
            <ecNumber evidence="6">1.1.1.157</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_00925</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.157" evidence="6"/>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008691">
        <property type="term" value="F:3-hydroxybutyryl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022694">
        <property type="entry name" value="3-OHacyl-CoA_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006180">
        <property type="entry name" value="3-OHacyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006176">
        <property type="entry name" value="3-OHacyl-CoA_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006108">
        <property type="entry name" value="3HC_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00725">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02737">
        <property type="entry name" value="3HCDH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000105">
        <property type="entry name" value="HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00067">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3HCDH_N" evidence="5">
        <location>
            <begin position="3"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="3HCDH" evidence="4">
        <location>
            <begin position="185"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="8"/>
            <end position="13"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="273"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="2">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000105-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000105-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD91182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="296" mass="32191" checksum="98AA474D24002CC5" modified="2019-11-13" version="1">MKNIAVIGAGTMGNGIAHTFAQSGFKVTLIDIREASLERGLDTISKNLDRMVAKEKISEADKTTTLEHISTTTSMESGVKNADLVVEAATENVDLKLKIFKQLDDICKPEAILASNTSSISITQIAAVTSRPQQVIGMHFMNPVPIMKLVEIIRGYSTSDDVTKSIMELSKTLGKVPTEVNDYPGFVANRILMPMINESIETLYNNVAGVEEIDTVMKLGMAHPMGPLQLADFIGLDVCLSILNVMYDGFKNPKYAPCPLLVNMVAAGKLGVKSGEGFYDYAESRKAEHVAKQFVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMP3</accession>
    <name>A0A5C6ZMP3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA-directed RNA polymerase subunit omega</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_01050</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006110">
        <property type="entry name" value="Pol_omega/Rpo6/RPB6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01192">
        <property type="entry name" value="RNA_pol_Rpb6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01409">
        <property type="entry name" value="RNA_pol_Rpb6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD91336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="109" mass="12828" checksum="972FB4237E6E335B" modified="2019-11-13" version="1">MDLKKTNAPVSTVTYNRNILDAPTDNIYEAIAVISKRAEQINTDIRRELVDKLEEFATYNDSLEEIFENKEQIEVSKFYEKLPKPHALAVQEWLDDKIYYRNTDDDVQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMV2</accession>
    <name>A0A5C6ZMV2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Membrane or secreted protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_05875</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="67" mass="7166" checksum="307B7223EAFD39B0" modified="2019-11-13" version="1">MKLIIITLILLGLGVAGIAIKIWAKKDGKFAGTCASQNPMLNKDGDACGFCGKTPEQYENCNEPQHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN53</accession>
    <name>A0A5C6ZN53_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="19"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="187" mass="21520" checksum="3F96C08176F49C51" modified="2019-11-13" version="1">MKQILSILSCLALLFLSSCDQRSSEKERLENAISEFNQKQTVLETQTFYPETYTEIKTDSIISDTFKVSISNYSNMQKTIVLNEKPSVKTEASKAHRVFESDVLVAVQNKVIFEGHFSAVDFKNNNTSEFWKDATLEHIWVNQDQSDETQLLLGVSIVNPKSKAYKYYEMRIDHFGKQSIQLIEETS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN91</accession>
    <name>A0A5C6ZN91_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="133" mass="14896" checksum="99662157A39BB35C" modified="2019-11-13" version="1">MECQNGKNLYASKKLVADGAEVKEGQEIALVTIDEDQVETVKALTNGTIKFLMEEGPFIFNSDSGKELIEQGAHYLAEIKYDTPVPLRHPNGDIRENQIPFIVVWLILGATFFTFRMGIIKISRGFTSNFLIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNG1</accession>
    <name>A0A5C6ZNG1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC-F family ATP-binding cassette domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_05645</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037118">
        <property type="entry name" value="Val-tRNA_synth_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="2"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="328"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="565"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="360"/>
            <end position="367"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD90220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="635" mass="72464" checksum="0065A7910186780F" modified="2019-11-13" version="1">MLNIHNLSISFQGEYLFEEITFKLSAGDRVGLIGKNGAGKSTMLKILSKEMEPDSGQIAADKNLSIGFLKQDIDFVLGRTVLEESYEAFQEIKDLEGKMEHINTQLAERADYESEGYNQIMIDLNDVQHQYEIIGGYNYQGETEKILQGLGFKREDFEKLTDTFSGGWRMRIELAKLLLQNNDILLLDEPTNHLDIESIIWLESFLKGYVGAVVIVSHDKMFLDNVTNRTIEISLGRIYDYPKPFTQFMVLRNELKAQQLASQKNQQKQIDQTEKLIEKFRAKASKATMAQSLIKKLDRMDRIEVDEDDNSVMTLNFPVSVIPGKVVVEANQIAKTYGKNHVLSNVNLMIERDSKTAFVGQNGQGKSTLAKIIVGELEYKGHLKLGHNVQIGYFAQNQAEYLNGNKTVLDTMIDAANETNRSKVRDILGSFLFRGDEVEKYVKVLSGGERNRLALAKLMLQPLNVLIMDEPTNHLDMKSKNVLKGALKKFAGTLVVVSHDRDFLQGLTNVVYEFKDQHIKEYLGDIDYYLQQRNVENLREVEKRTVIKEVPKETSKQSYEDQKKLKSLNNKLSNIESKIASLEKDIKKDDVDLATNYNKTIADNSFFDRYQSKKKKLKQLMSDWENVTLDLEGIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNP5</accession>
    <name>A0A5C6ZNP5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Gliding motility-associated C-terminal domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_04445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026341">
        <property type="entry name" value="Bac_Flav_CTERM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04131">
        <property type="entry name" value="Bac_Flav_CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022925447" evidence="1">
        <location>
            <begin position="21"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="592" mass="64503" checksum="9114EB93A220991E" modified="2019-11-13" version="1">MFLKQNLLCFLVLMSLYAEAQDIALYQQFNGRFDYTAIGNSFNLTENGTSIDCEIHTEASAELTLNANQSIVAAYLYWAGSGTGDFEIKLNGQAISAERSFNDSLDENRVFFAGFADVTSQLQLGGSGMYTVSDLDLSEVIAPYCSSGTNFAGWAIAVIYEEDSLPLNQLNVYDGLQSVPENLTITLNNLNVLDNQGAKIGFIAWEGDAALAVNEQLSINGNAISNPPLNPINNAFNGTNSFTGATNLYNMDIDVYDIQNNIDVGDSAATISLTSGQDFVMINNIITVLNSQTPDASIRLNDNAIACGDSNILLNYTVYNTNSTDPLPGQTPIAFYVDGVLVGQTTTQNEIAINASETGSIDIMIPETDATSIEITAVVDDDGTGNGIVTENNENNNSNTQVLELLILSPVIPIAGALACNEGLGTGTFDLEAILNAQVNTSLNITFYESLEDLAADTFEITNPSAYTSNSDMQMVYAKVANLPCYERYAFALTVENCPPFVPQGFSPNEDGANDWFNIQGLYDIFERHELKIYNRYGTLIFEGDNSLRWEGRINRGLNNHGNLVPVGTYFYILNLNDPNYKPIQGWVYVNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNV9</accession>
    <name>A0A5C6ZNV9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">S8 family serine peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_01710</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04842">
        <property type="entry name" value="Peptidases_S8_Kp43_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034058">
        <property type="entry name" value="TagA/B/C/D_pept_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022829558" evidence="4">
        <location>
            <begin position="21"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S8" evidence="5">
        <location>
            <begin position="116"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="Por_Secre_tail" evidence="6">
        <location>
            <begin position="578"/>
            <end position="656"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF18962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD90706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="658" mass="71827" checksum="C5F7E286CA357FB9" modified="2019-11-13" version="1">MKIKNITLFMFLFLSLTFFAQNRTDKTIENLSKENKILLEKLLIEESRIETRISTYLINNPDTKRRFVDSKGRVMEIRDIYDNKPIYVSTSNDNAAMATKTNTLQPGGVLNLNLTGSGMTVGVWDGGPVQASHPEFSNSNETASRITIIDNVVVDGDTGFSNHGTHVAGTISAKGVVSEAKGMAPDVLIKSYNWTNDNSEILLAINDIDAPIILSNHSYGTPILQNNEDLLPSWLMGAYNSSAANIDMIIKNNPQYLMVTSAGNSGTQSYPGGLFAGFDKLTTDKNAKNNLVIANANPSIAPFTNELTNLVINNSSSQGPTDDLRIKPDIAGDGTNLFSPIANDEYATYTGTSMSAPNVTGTLVLIQEYYQQLYSQYMLASTIKGLVCHTAIDDNMRSGPDPVFGWGFLNAFGAANVITSSTLGASQIEELNLYNNDEFSFTFFAQAGQRLSATICWTDMPGAAVIDELNSFSPKLINDLDLRITRNGETFFPYKLEYSQTGGFSNTNTGDNFVDNIERIDIEAPEAGSYTLTVTHKGTLRGNVGGPFDPQSQDFSLILTGNNVTLSSGNEDFTDFNIWPNPAGDYVNISLSTIKQSGRVDMSLFDIQGRLISEIALESSEFLSGSYMLNTSHLPEAIYLLEIKGVNQSAIKKIVIKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNZ1</accession>
    <name>A0A5C6ZNZ1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carboxypeptidase-like regulatory domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043741">
        <property type="entry name" value="DUF5686"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18939">
        <property type="entry name" value="DUF5686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023041324" evidence="1">
        <location>
            <begin position="20"/>
            <end position="820"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="820" mass="93340" checksum="58B2595547005288" modified="2019-11-13" version="1">MKQKLLLTLGLLSFAFSQAQIQGNITDQNDEALPFVNVFIENTYKGTTSNEDGFYELNIKTPDTYTVVFQFLGYKTVKKTVEISKFPFQLDAQLGEEQISLNEVVINSENNPADAIMRQAIAKRQENLEKIQSYKADFYSRGLIRIKDAPEKILGQEVGDLGGGLDSTRSGVIYLSETISKLEFMRPDRLKEKILASKVSGNSSGFSFNNAIDVDFDLYESTIELGNQIVSPIANNAFGYYRFKLEGVFYDDRGNLINKIKITPRRENDPVFEGFLYIVEDQWSIYAAELDITGTQARLTAVDKITITQNYSYSEADKIWAKISQNIDFKYGLFGITGDGRFTAVYSNYEFNLGLSKKDFSREIVSFADKANKKDSTYWKSVRPVPLTSEEMTDYIKKDSIQIVKDSKVYKDSVDLVKNKFKFGDLLSGYSYNNTYKEWSAGITSPIQTITFNTVQGWNANVGGFYRKSYDDFNRFFSINGSLNYGFSDERLRGSVSATYKFNNISRPFLTVSGGVTTAQFNASEPISQLLNTSFSLFAEKNYLKIYEKSFAQVAYSNEFFNGIRINSILAYERRQALFNTTDQVWYPQDDREYTSNNPQDESAFGIAPFATHNLMKFGLDARINFAQNYLSYPDGKFNLPNEKYPTLSVGYEKGFGSSNDNYNYDQVKLRVNQGFDVKDKGRFQYNLKAGKFFNADDIAFVDYQHFNGNQTQIGAGSYINVFNNLPYYAASTNDSYLEMHAEHDFNGFILGKIPLLQKLNFNLVLGAHALATPDNKPYQEYTIGLDNIGWGKFRFLRLDYLRSYQSGFQSDAIIFGLKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNZ3</accession>
    <name>A0A5C6ZNZ3_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">OstA-like_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_03430</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005653">
        <property type="entry name" value="OstA-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13100">
        <property type="entry name" value="OstA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022685674" description="OstA-like_N domain-containing protein" evidence="2">
        <location>
            <begin position="40"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="domain" description="OstA-like_N" evidence="3">
        <location>
            <begin position="73"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="571"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="571"/>
            <end position="608"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD90430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="618" mass="70579" checksum="DEF3468F59A42E42" modified="2019-11-13" version="1">MAQARVRLTIFEFKSFRLKTTIQYFLLLCCCFSAVQLHAQEPKKIRIEYSGFTVKDSLLGENITTFVRSDQSQIHVVHEGIDMYCDKAIYYQNEDFIEAFSNVRMNQGDTINMTSKYVEYSGITQLAFAAGNVVLTEPQSVLTTDTLYFDRTKQEAFYNSKGKVVRDSSGTITSQVGRYYMTDSKYRFLKDVVLINPEYTLKTNQLDFYSETGFAYMYGPSTIVGEASTVYCERGFYDTNNDIGYFIKNSRINYDNRIVEGDSLYFDRNKSFASATNNITVTDTINKSIITGHYAEVFREQDSVFITKRALAITIQEKDSVFIHADTLKVTGKPEHRITRAYYNAKMYKSDMSGKADSIHADHKTGLTQLINLKRFNTGDAFSVKRKPLIWNMGNQMSGDSIHLISNVKTEQLDSLKVFDNAFLVSKDTLSEGFNQISGQKLIGLFADNELYNVDIIKNSEVIFYTRDDKDSLVGINKSKSGSINLKFDGPYKIITLINQIDGDIYPESKFPQNARKFRNFDWRGDEQPQSVEDLFKDDPPLELVNIKGLDAFVPEEEFFDTALFERIDDARKKDKDEVNKAERNIPKEAQQSRLKRDATKKAGATKQNKSADKQNGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZP00</accession>
    <name>A0A5C6ZP00_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Four helix bundle protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_01940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012657">
        <property type="entry name" value="23S_rRNA-intervening_sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036583">
        <property type="entry name" value="23S_rRNA_IVS_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05635">
        <property type="entry name" value="23S_rRNA_IVP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158446">
        <property type="entry name" value="SSF158446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02436">
        <property type="entry name" value="TIGR02436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="61"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="113" mass="13075" checksum="B989C8FE30EA0687" modified="2019-11-13" version="1">MKQFDLDDRLEDFAASIIRFYSNNPKTFAADYLAKQLIRSSCSAALNFGEFLGAASDKDKANKLRIVLKELRESIRNINIQTKALIYKKEDLESLNKENDELIRIIVTILKRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPK4</accession>
    <name>A0A5C6ZPK4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chemotaxis protein CheB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_01400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000156">
        <property type="term" value="F:phosphorelay response regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008984">
        <property type="term" value="F:protein-glutamate methylesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035909">
        <property type="entry name" value="CheB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011247">
        <property type="entry name" value="Chemotax_prot-Glu_Me-esterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000673">
        <property type="entry name" value="Sig_transdc_resp-reg_Me-estase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01339">
        <property type="entry name" value="CheB_methylest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036461">
        <property type="entry name" value="Chmtx_methlestr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52738">
        <property type="entry name" value="SSF52738"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50122">
        <property type="entry name" value="CHEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CheB-type methylesterase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="13"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="40"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD91271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="332" mass="36592" checksum="76539EC28EE76EA7" modified="2019-11-13" version="1">MSTPKFIIVVGTSAGGLNALIEFVSQLKAEMDAAVFIVMHLSRASISDFLVHRLQPFTTLPCALAKEGAAVKKGHVYIAAPNAHLLVKKNKMILGHGPEENRWRPSIDVLFRSAAAAFSTRVIGVVLTGSLDDGTTGMIAIKRSGGTCIVQDPNEAEYPDMPLSVLNNMEVDHCVSLGQMGELIFQVTQTLPEEIPAPQDILIESQIAERVVVDYENVKQIGEKSIYACPDCGGGLWGIESEKGITNRYRCHIGHSYSEKDLVVKQGEVLESTLWVALRIMEERGTLLKKMETDNSKRGYSKMATSYREKFENIQLHVDQMKAVLYASQKII</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPN2</accession>
    <name>A0A5C6ZPN2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Acyl-CoA dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ESY86_01585</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025878">
        <property type="entry name" value="Acyl-CoA_dh-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12806">
        <property type="entry name" value="Acyl-CoA_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="8">
        <location>
            <begin position="39"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="162"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="282"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_C" evidence="9">
        <location>
            <begin position="473"/>
            <end position="593"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD91301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="603" mass="67200" checksum="F57AC4EFE6144879" modified="2019-11-13" version="1">MANTYIEMETLKFLLFNVHDLKGVLQQERFSEYDEESINMMLDSVKDFSDKEMYPYYKEMDENPAHFKDGEIIVHPQVTKYMKAGGEMGFLSGSFSYEAGGMQMPSMVVNASAFIQEAANNHLPGYIGLTVGAAELIEHFGNQSLKDTYVPKMMAGEWGGTMCLTEPQAGSSLSDIVTTAFPNGDSYKISGQKIFISGGDYKGAENIVHLVLARIKGAPAGTKGISLFVVPKNRLDDHGNLEDNNVTTVGDFQKMGQKGYCTTHLFFGDKEDCSGWLVGEPNKGLKYMFLMMNGARIAVGRGAAAIATGAYHASLNYAKERPQGRELQKTGKKDASQEQTMIINHPDVRRMLLLQKVITEGALSLVFLTSRYQDLSQSLPDAESREKYKLLLEILTPVVKTYPSEMGITSINNGVQVLGGYGFCSDYILQQYLRDIRISAIYEGTTGIQSQDLLGRKVTMENGKALQLLSEEIMNSIEESMAYETLRPLAEKLGSKLELTQKVLKSLMGYAKEGDYQRFLADATPFMEFFSTIVVAWQWLDIGREAQKAMISGDASFNAEFYENKIHAMQFYFKYELPKTTGLAEVLMDKQSLTLNTEKQVFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZQN6</accession>
    <name>A0A5C6ZQN6_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">DNA repair protein RecN</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4 5">Recombination protein N</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">recN</name>
        <name evidence="8" type="ORF">ESY86_01035</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">May be involved in recombinational repair of damaged DNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the RecN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004604">
        <property type="entry name" value="DNA_recomb/repair_RecN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11059">
        <property type="entry name" value="PTHR11059"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003128">
        <property type="entry name" value="RecN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00634">
        <property type="entry name" value="recN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMC_N" evidence="7">
        <location>
            <begin position="2"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="158"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="318"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00033408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR003128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD91203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="550" mass="61142" checksum="55F17E3B5DAB6CB0" modified="2019-11-13" version="1">MLTQLSIKNYALIDDLQVNFNNGLSIITGETGAGKSILLGGLSLILGKRADLSSIKDNSKKCVIEATFDIAKYNLKVLFKSEDLDYEAVTIIRREILPSGKSRAFINDTPVNLDSLQVLGEHLLDIHSQHQTLQLTNDDFQFQVIDALADNLKLLNGYQQELQSFKALDKELKALQAQKAEAIKELDYNLFLLKELTDANLVAGELESLEEEYETLNNVEEIKEKLAASHELMSNEEVGITLNLTEVKNQFAKLATMASQYKVMYERVSSSLIELADIFSEMESLQDQLEADPNRLELVNAKLQVLNNLSQKHSVASVEELIAIREDLKSKVEITENLDEAILAKEKQIASVEKQLNQIAKELHDKRLAVIPKLVSQLESILGNLGMPNAKFQVELQTRKGFLANGTDALAFLFSANKGGQFNELKKAASGGELSRIMLAIKSVLAKYTHLPTLMFDEIDTGVSGEISNKMGAIMQQMSKKMQVFSITHLPQIAAKGDTHYKVYKEDVNNVTQTQMKQLTAEERIVEIAQMLGGKDISSSAMAHAKELLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZR63</accession>
    <name>A0A5C6ZR63_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type II toxin-antitoxin system RelE/ParE family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_00335</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009241">
        <property type="entry name" value="HigB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05973">
        <property type="entry name" value="Gp49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="113" mass="13819" checksum="113D6A6BE1BCA7D3" modified="2019-11-13" version="1">MIKRFETILLEQAFEFIQKQNLKARKKIFQNIRRAEQLSDPKFFKKLTDEIWEFRTLYSGFQYRLLAFWDKENKAETLVLATHGVIKKTSKVDKKEIDKAERIRRNYFKNKQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6Z8M2</accession>
    <name>A0A5C6Z8M2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_20795</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000129">
        <property type="protein sequence ID" value="TXD85797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD85797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="83" mass="10050" checksum="E3B96CEF459881CE" modified="2019-11-13" version="1">MSNFKEIKSEIEKYANDSNLTELQIVEKLEKHYFDKKVNENLKLYKKGKKKVSEITKDLKISPRKFYAILEKKKIEHKIYKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6Z9N1</accession>
    <name>A0A5C6Z9N1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">2OG-Fe(II) oxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_20105</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000057">
        <property type="protein sequence ID" value="TXD86482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0847">Vitamin C</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="7">
        <location>
            <begin position="108"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD86482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="213" mass="24795" checksum="F11BBE616D0C9FDC" modified="2019-11-13" version="1">METLSNAMSFIENAMYEQIISDLAINQYSITDHFFSAETVSVLRASLLAKHDEDRFKKAAIGNRVNEVIVKSIRGDHILWIDENMANTAEALFFNQINDLVGYLNRTCFMGILHKEFHYALYPKATFYKRHIDTFKNDDRRKLSFVCYLNDEEWQPENGGELVLYLDENGREAPKIIYPLPGRVVIFESQIIEHEVKPVEVERLSITGWLKTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6Z9Z3</accession>
    <name>A0A5C6Z9Z3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Universal stress protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_19650</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal stress protein A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000044">
        <property type="protein sequence ID" value="TXD86658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="2">
        <location>
            <begin position="5"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="Usp" evidence="2">
        <location>
            <begin position="144"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="385" mass="43944" checksum="6FCB74E89F7B26AB" modified="2019-11-13" version="1">MILLEKILFPVDVNIDTKEQLNSAMKIAKLCDSKIFIMHVLPDEGLNDAIKQIVIDYATETLNKIKAIFEKEGVEVSEPIIEYGKPVDSILKMAAKEHVNLILTGCGNKNEKEKFKRGSTAAELMRQSDIPVWVVKSGKENKLDNILCPIDFSEPSKYALNNAILLSEFFDANLTILGVFEPYEHLSPRFKVDINEINSHRREETKNKMDEFIKDFDLKGINHKIDIKSGAAHIEILETIKEEGHDLLVMGTHGRSGINRFVMGSVTEKVTREVPCSFMTTRTDVIIQLKINNEITEITEIETHFKKANDLVHGNFYKEAIGKYLICLEINSMHIPSMFKLTKVFKIIGDHAKAEYYSAMAKDVLTRLCDEKIEKEIRKHYLLED</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZA66</accession>
    <name>A0A5C6ZA66_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_20495</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000080">
        <property type="protein sequence ID" value="TXD86224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="208" mass="24920" checksum="7B26E35B26BDBE33" modified="2019-11-13" version="1">MEELFNDFTNQTGIELPQSIIKYYLDGRNSNSQFVRLFKSNFDSVEKRKYPYLKVLLSEMFAREILTLIHEYSYDERINDLFYEIYNYHYKDKQIIFDTNKEDFVIDEIFYATIDYNYKKNQFKFPLIQNAYEKLDSNPEFLKVILILHGSCGGDGGIIVRGKNIGYDSGYIHGEKTEVEFNDKIFEYNGYSFENYEKIHKVIEEKFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAF7</accession>
    <name>A0A5C6ZAF7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19790</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000048">
        <property type="protein sequence ID" value="TXD86594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="112" mass="13030" checksum="7AD0EDAFA36C7D02" modified="2019-11-13" version="1">MNYKWNKTNNRGQSQTGFVDIYQSNLQKNAILIVNYLPQINGKNQIVMVTILLEGEKTDWSEGKINDILQDSGDYVKNNEHNYSVDFLNTQLFYLESLNDFSYLNHGDYTPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAJ4</accession>
    <name>A0A5C6ZAJ4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="10">UDP-2,3-diacylglucosamine diphosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ESY86_20095</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000057">
        <property type="protein sequence ID" value="TXD86480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016462">
        <property type="term" value="F:pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043461">
        <property type="entry name" value="LpxH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010138">
        <property type="entry name" value="UDP-diacylglucosamine_Hdrlase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34990">
        <property type="entry name" value="PTHR34990"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34990:SF1">
        <property type="entry name" value="PTHR34990:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="2" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="9">
        <location>
            <begin position="8"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD86480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="251" mass="29689" checksum="61C4F7A6EEA42736" modified="2019-11-13" version="1">MQIPKGKKIYFASDNHLGAPTKEESFPREKKFVAWLDEIKTDAAAIFLLGDLFDFWFEYSTVVPKGFVRTLGKLAEIRDSGIPIYFFVGNHDLWMNGYFEKELNIPVYHKPMEFTFNNKTFFIAHGDGLGPYDKGFKRMKKVFTNPVFKFLFKWLHPDIGMRIAQYMSVKNKLISGEHDAKFLGEDNEWLILYSKSKLEEQHRDFFIYGHRHLPMEIDLGQDSKYFNLGDWIQYFTYGVFDGEHFEMKTYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAQ3</accession>
    <name>A0A5C6ZAQ3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">KpsF/GutQ family sugar-phosphate isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_19370</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the SIS family. GutQ/KpsF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000039">
        <property type="protein sequence ID" value="TXD86768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901135">
        <property type="term" value="P:carbohydrate derivative metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05014">
        <property type="entry name" value="SIS_Kpsf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004800">
        <property type="entry name" value="KdsD/KpsF-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035474">
        <property type="entry name" value="SIS_Kpsf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004692">
        <property type="entry name" value="KdsD_KpsF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00393">
        <property type="entry name" value="kpsF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0129">CBS domain</keyword>
    <keyword evidence="9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="SIS" evidence="8">
        <location>
            <begin position="36"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="7">
        <location>
            <begin position="204"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="7">
        <location>
            <begin position="270"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3 4">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="216"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="268"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Catalytically relevant" evidence="5">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <feature type="site" description="Catalytically relevant" evidence="5">
        <location>
            <position position="106"/>
        </location>
    </feature>
    <feature type="site" description="Catalytically relevant" evidence="5">
        <location>
            <position position="147"/>
        </location>
    </feature>
    <feature type="site" description="Catalytically relevant" evidence="5">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR004692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR004692-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR004692-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR004692-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD86768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="321" mass="34637" checksum="E38267B92C2D19B7" modified="2019-11-13" version="1">MNIEASILKTARKTISLERDAIAHLLDLLTADFANAVSLIYNSKGRVIITGIGKSAIIANKIVATLNSTGTPAVFMHAGDAIHGDLGLILEEDVVICISKSGNTPEIKVLVPLIRRSKNKMIAITGNDTSFLAQQADFILNTYVAQEACPNNLAPTTSTTAQLVMGDALAICLLELRGFSSKDFAKYHPGGALGKRLYLRVNDLSSQNEKPEVSPTTSAKNVIVEISEKRLGVTAVVENHKIVGIITDGDLRRMLTKSDAFLHFTAKDIMSSNPKTIDEDAMAVDAMDLMETHSITQLLVEKEGNYAGVIHIQDLIKEGII</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAS5</accession>
    <name>A0A5C6ZAS5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_18200</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000030">
        <property type="protein sequence ID" value="TXD87065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004866">
        <property type="term" value="F:endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011625">
        <property type="entry name" value="A2M_N_BRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011626">
        <property type="entry name" value="Alpha-macroglobulin_TED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021868">
        <property type="entry name" value="Alpha_2_Macroglob_MG3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041203">
        <property type="entry name" value="Bact_A2M_MG5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041462">
        <property type="entry name" value="Bact_A2M_MG6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041246">
        <property type="entry name" value="Bact_MG10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001599">
        <property type="entry name" value="Macroglobln_a2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002890">
        <property type="entry name" value="MG2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00207">
        <property type="entry name" value="A2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07703">
        <property type="entry name" value="A2M_BRD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17973">
        <property type="entry name" value="bMG10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11974">
        <property type="entry name" value="bMG3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17972">
        <property type="entry name" value="bMG5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17962">
        <property type="entry name" value="bMG6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01835">
        <property type="entry name" value="MG2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07678">
        <property type="entry name" value="TED_complement"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01360">
        <property type="entry name" value="A2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01359">
        <property type="entry name" value="A2M_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="SSF48239"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="A2M_N_2" evidence="3">
        <location>
            <begin position="997"/>
            <end position="1139"/>
        </location>
    </feature>
    <feature type="domain" description="A2M" evidence="4">
        <location>
            <begin position="1204"/>
            <end position="1293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD87065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1861" mass="208821" checksum="C4DAD24295A4FB05" modified="2019-11-13" version="1">MNSKYIFTCLVCLTMLFSCKEKDSAASETDNLFKFRDYISYTSSGLQSVADPIAITLSTDVQGWEMGQEISDEIMSITPHVEGKITVANAHTLLFKPDENLEPATEYAVTLKLGAIYKDLPSEFENYSFHFKTITPNFSLSTNNLQSYSKKWQYLEAVIKSADVMSLSQAKQLVQATQNGEALKLQWNEINDNSKYFEFKIDSINRKIEDSEILVKWNGKPIKSNTTGENKLTIPGINNFTIVSVEAFKSPEQIVSINFSDPLKKQQNFDGLVTIQGVKSPKFIVNGNVLKVYPDGKLVGNIQVDVFQGINNSDGFKLKKPFSEAISFEEEKPMVRLISNGTILPNSEDLKFNFEAINLSAVDVRIIKIFEDNILQFLQDNTMNSDNGNEIRRVGRRIAKQTIQLQTAAENSGKWKAYSIDLSKLFKADAGAIYRVELSFKKMYSLYDCEANATTSVENQDDDYDDYYHEEDYYGSDYAETYTEDEELREEEYWDNRSYDYKNYRYNYRERDNPCHEAYYNQNRIVAQNVLASNLGVIVKQGANNNYYFAVTNILNTNPEAGAKITLYNFQQQEIGSVSTDGDGLAQYKSNKYAYFAIVEKGKNSSYLKLADGNSLSLSKFDVSGNQLQRGLKGYIYGERGVWRPGDTLFLTFMLNDKANKLPVGHPVKMEVTDPAGKLIYKAVTSDNLNNVFSFPVATTSEGKTGNYSAKVSVGGAQFYKALKVETVKPNRLKIKVDFEEEVLTSKTPLDGTLDVAWLHGAPAKNIKAEIKAKFSSSYTGFKNYKDYIFTDPTRTFDTEELIVFEGNVNAEGKANINKQLEVGKNAPGMLNVQFLVRAFENGGDFSLDAFTKTYSPYASYVGLRSPEGNAYGAYFTDTKQSFDLAVVDKAGKPVKRDNLEVKIYKIEWRWWWNSSYDNLSSYVSSTYHRPVMDQIVATDANGKATFDIKIPEDERGRYLIRVTDPVSGHATGRTAYFYKNWSNISPGNDKEAAKMLVFAADKEHYNVGETAKITFPSSSEGRALVSIENGSDVLDYKWVKTTQGESTVNIPVSSEMAPNVFVNISLLQPHAMTSNDLPIRLYGVIPIMVEDPKTILRPKLNMPDVLRPEQEFEVKVSEKNNKAMTYTIAMVEEGLLDLTRFMTPNAWDEFYAREALGVKTWDIFDDVIGAYSGSIDQVFAIGGDGSAMKGKNKKANRFKPVVTYLGPFELKAGGSKTHKLKMPNYIGAVRTMVVASNAEDEAYGNTDKSVQVKKPLMVLATLPRKLSPGEKVTLPVTVFAMEPKVKNVNISLKLSDGISVVGKSSATMTFAKPDEQMAYFELDVSKANGINTVEVIATGNGEKSIYKVELDVVNPNPISSRYENTKLEANASETLEFSTFGVVGSNSASVEFSTLPPMDFTRRLQYLIQYPHGCLEQTTSSVFPQLFLNDIFDLTYEKRQNIQSNIENGIKRLGNFQRPNGGMSYWMGENSVNDWSTSYAGHFMIEAEKKGFVLPLGFKSNWLNYQKQAARDWRPSYSNYNSDLAQAYRLYTLALAGSADLASMNRLREFSEISNEAKWRLAAAYALAGQKEASEQLSKGANIDFQAPKYNYYTYGSLDRNRAMALETMIITKNPKARALSETIAKQLSSKDWMSTQTTAFSLLAMAKMVEANGGKNMNLSYSFNGKSENIDTKNAIAERSLDIKEGSNSLKVMNNIGNLVYVRVLNSGKLQLGEELAEQRGLSISVNYKDLKGNTMNISNLKQGEDFVATVSVSNLTSEQVNDVALTQIFPSGWEIVNTRFTDFGDTTVSQARYTDIRDDRVNFYFDLPRKGKYGSKTFTVMLNASYLGTYYLPGTQVEAMYDHDYFVRTKGEWIKVTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAU4</accession>
    <name>A0A5C6ZAU4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_18125</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000030">
        <property type="protein sequence ID" value="TXD87085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023023199" evidence="2">
        <location>
            <begin position="21"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="328"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="538" mass="61305" checksum="1BF4C01F512608BD" modified="2019-11-13" version="1">MGSVAIWSLFFSLFSLFSFAQVSSSIDSTTIKIGEQITYKIQVEADSSDFVLFPDGQTFMPLEMIEAYKTDTTKTNAKFKLIKKYGLTQFDSGAYTIPRQKITIGETVFYTDSLKVRVNAIEVDTTKQQLYDIKPMIKVEKATSYFWLYVLLSVLIIALVAFALYWFIWRRKPLTEAEEIALLPPYDRAKLALQKLDETDYLQRSELKGYYSELTFIIRKYLDEKVYDRALESTTDELISRLHLLKDANKIILSKEDIRNIELILKRADLVKFAKSAPDLELAKLDRTTVDMEIDIVKDALPQPTEEEKLLDQRYKADEDRKKKREKIWLTVAASVLILAATFIGFGLKYGFPYVVDSIVGEDTKELLEGTWVSSEYGIPPVTIATPAVLERVEMQAIDSTQATRRSAFSYGSLEQTLDIEVSTTQYDPQKEQKIDVNAEAEQAIRGFENNGAKNLLVKREKFETPNAAQGLKVFGSLELPVEGSSNFKTGEYTILIFVSEDKSVLQKIVLAWDNQNPYANDIMERVINSIELKKAED</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAX2</accession>
    <name>A0A5C6ZAX2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20035</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000055">
        <property type="protein sequence ID" value="TXD86503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023107927" evidence="1">
        <location>
            <begin position="20"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="67" mass="6958" checksum="8EB441251839552C" modified="2019-11-13" version="1">MKNLFLTLAFVLGAASSFASDSTEEAVALERTCVPTTLSCGIEGWSCGDTTTEILENAIAADEALCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBD0</accession>
    <name>A0A5C6ZBD0_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Riboflavin biosynthesis protein</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="11">Riboflavin kinase</fullName>
                <ecNumber evidence="11">2.7.1.26</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="11">Flavokinase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="11">FMN adenylyltransferase</fullName>
                <ecNumber evidence="11">2.7.7.2</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="11">FAD pyrophosphorylase</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="11">FAD synthase</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="13" type="ORF">ESY86_18465</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2 11">
            <text>ATP + FMN + H(+) = diphosphate + FAD</text>
            <dbReference type="Rhea" id="RHEA:17237"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="EC" id="2.7.7.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + riboflavin = ADP + FMN + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14357"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57986"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Cofactor biosynthesis; FAD biosynthesis; FAD from FMN: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 11">Cofactor biosynthesis; FMN biosynthesis; FMN from riboflavin (ATP route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the ribF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.26" evidence="11"/>
    <dbReference type="EC" id="2.7.7.2" evidence="11"/>
    <dbReference type="EMBL" id="VORO01000031">
        <property type="protein sequence ID" value="TXD87041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00276">
        <property type="reaction ID" value="UER00406"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00277">
        <property type="reaction ID" value="UER00407"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003919">
        <property type="term" value="F:FMN adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008531">
        <property type="term" value="F:riboflavin kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006747">
        <property type="term" value="P:FAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009398">
        <property type="term" value="P:FMN biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02064">
        <property type="entry name" value="FAD_synthetase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015864">
        <property type="entry name" value="FAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023468">
        <property type="entry name" value="Riboflavin_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002606">
        <property type="entry name" value="Riboflavin_kinase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015865">
        <property type="entry name" value="Riboflavin_kinase_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023465">
        <property type="entry name" value="Riboflavin_kinase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22749">
        <property type="entry name" value="PTHR22749"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06574">
        <property type="entry name" value="FAD_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01687">
        <property type="entry name" value="Flavokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004491">
        <property type="entry name" value="FAD_Synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00904">
        <property type="entry name" value="Flavokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82114">
        <property type="entry name" value="SSF82114"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00083">
        <property type="entry name" value="ribF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0274">FAD</keyword>
    <keyword evidence="5 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 11" id="KW-0288">FMN</keyword>
    <keyword evidence="11 13" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Flavokinase" evidence="12">
        <location>
            <begin position="176"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR004491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TXD87041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="305" mass="34387" checksum="A8E1B80CAC628391" modified="2019-11-13" version="1">MAKEQKHPESVITIGTFDGVHIGHQKIINRLVSVSKKKGLKSVVLTFFPHPRMVLQPDFDLKLLHTIDERKKILSKFGLDQLVVKPFTKAFSNLSAHDYVRHILVDELNAKHIIIGYDHHFGKNRSANIEDLKIFGKEFDFQVEEISAQDIEEVSVSSTKIRTALTEGDVQTANAYLGYAYFLSGSVIKGKGLGKTINFPTANLFIEAAYKLIPKNGVYVVSAHIEGKTVYGMMNIGTNPTVETKDKPSIEVHFFKLDKDLYGQDLVVEILHRLRDEHKFESLEQLQAQLETDKLNAHNLLGIHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBD5</accession>
    <name>A0A5C6ZBD5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TetR/AcrR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17285</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000026">
        <property type="protein sequence ID" value="TXD87315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041673">
        <property type="entry name" value="TetR_C_23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17931">
        <property type="entry name" value="TetR_C_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TetR_C_23" evidence="1">
        <location>
            <begin position="84"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="218" mass="25548" checksum="3C5CA5F4D5E34A94" modified="2019-11-13" version="1">MAKKKNSSANDIISMYMDFVLEHNKQPSTVYAFAKANNFEESKFYEFFGSFEAVEEHVFKAFFDNSLVVLEKSPEYQNFDPRNKLLSFYFTFFENLTANRSYVIYALKEQKNDMKRLKVLTKLKGAFTHYIANLGIDLIDIKQAQLDKIQTRGLKETAWLQLLLTMKFWMDDTSASFEKTDIFIEKSVNTSFDVLDVAPVRSLIDFGKFIFKERVKMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBV5</accession>
    <name>A0A5C6ZBV5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">T9SS type A sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_19010</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000036">
        <property type="protein sequence ID" value="TXD86847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045474">
        <property type="entry name" value="GEVED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20009">
        <property type="entry name" value="GEVED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023133536" evidence="1">
        <location>
            <begin position="18"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="GEVED" evidence="3">
        <location>
            <begin position="87"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="Por_Secre_tail" evidence="2">
        <location>
            <begin position="197"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD86847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="267" mass="28290" checksum="64F61E39B155D755" modified="2019-11-13" version="1">MKKITLAIALLTLGAQAQDFPSPYCEMAAGTTVEEITSVSFAETTITNANATSVLIDKLSTTVNVAPNGTYAITVEGNTAGAFDNNIVAFIDWNQNDVLDDANEIYPIGTISNSTGSDGASVTMDITVPADAVLGSTRIRVTKTYTDDESIAEVNPCAIEMNVGGYGVYPGFGQALDFTLNIATLGTNSFETKALSVFPVPTQSVLNIAYTSEINAVKIYNLLGQEVHAENTATAKLQLDVSLLSAGAYIVKLVTARGQHQFRMLKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBY6</accession>
    <name>A0A5C6ZBY6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Carboxypeptidase-like regulatory domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_20330</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000066">
        <property type="protein sequence ID" value="TXD86379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="297" mass="34323" checksum="00CD9C1C89541DB3" modified="2019-11-13" version="1">MKKLLAIIFLLISNFGFSQIKAVIFDKETKEKISYVNIWIENENIGTTSNENGEFVIDSSKGEILILSSLGYETMKINLKKIPSKIFLLPKSYELDEVIVSTKKENKEKVIGAFKDSEIGFFYATEKNPEIKARLFDFDSTYLETPFLKSIKLRIYSDVKNSKFNIRFYSVGENGQPDKPIYEKNIIGISKKGTKNLEIDLSDLNISFPSDGLFVSYEWLILEENEFKVSFLIKDSKKRIEKTLYEPKVGLLPTTQNTNSWLYKNGKWEKSERFKGNSPKPYLDNYEILAIELKLTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC08</accession>
    <name>A0A5C6ZC08_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_16185</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="141" mass="15719" checksum="29369A9BEB43570A" modified="2019-11-13" version="1">MPKLTINRKSETNNKARKIGVYIDGIRVGSIANGESQSYEVLAGRHEVSAKIDWCGSQIKSIDLKDSQTQTLALAGFKYGSVAGIVMLLFFGSYLIGKYVFDLKLYFLIVGTVLTFCYPLYFITFGRNHYLKLSEVTAAEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC54</accession>
    <name>A0A5C6ZC54_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">S9 family peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_18220</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S9A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000030">
        <property type="protein sequence ID" value="TXD87069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002471">
        <property type="entry name" value="Pept_S9_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023302">
        <property type="entry name" value="Pept_S9A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002470">
        <property type="entry name" value="Peptidase_S9A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02897">
        <property type="entry name" value="Peptidase_S9_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00862">
        <property type="entry name" value="PROLIGOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00708">
        <property type="entry name" value="PRO_ENDOPEP_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S9_N" evidence="4">
        <location>
            <begin position="33"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9" evidence="3">
        <location>
            <begin position="493"/>
            <end position="708"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD87069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="717" mass="80484" checksum="6BC64C4C10B32101" modified="2019-11-13" version="1">MKKLAFLSVSILLMVSCEDNSKDTKKDMAITYPETKKVDTVNNYFGVEVKDPYRWLEDDRSAETEAWVKAENETTFEYLNKIPYRDALKERLSKLWNYEKIGAPYKEGDYTYYSKNDGLQNQYVIYRYKTGEDPSTASLFLDPNTFKEDGTISLGGMSFSKDGKTLAYAISEGGSDWRKILVMNAETKEIVEDTLRDIKFSGMSWYKNEGFYYSSYDKPEGSELSAKTDQHKVFYHKLGTPQKEDQLIYGGSADEKHRYIYGNVTEDNHYLILSPRESTSGNKLLIKDLTTPNSDFQTILDNTESDSYIIENEGSKLFLVTNRNAPNQKIVTVDAANPAPENWVDFIPETENVLSPSSAGGYFFANYMVDAVSKVLQYDYDGKLVREVELPGIGSAGGFGAKKEEKELYYSFTNYVTPGSIYKYDIAYGTSELFNKPAIDFNPEDYESKQVFYKSKDGTEIPMIITHKKGLELNGNNPTILYGYGGFNISLTPSFSIANAIWMEQGGIYAVPNLRGGGEYGKAWHDAGTKMKKQNVFDDFIAAAEYLIDNKFTSSKYLAIRGGSNGGLLVGATMTQRPDLMQVALPAVGVLDMLRYHTFTSGAGWAYDYGTSEDNKAMFEYLKGYSPVHNVKEDVQYPATLITTGDHDDRVVPAHSFKFAAELQAKQTGTNPVLIRIETDAGHGAGTPVSKTIEQYADIFGFTLYNMGFEKLPNETK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC62</accession>
    <name>A0A5C6ZC62_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Acyl-CoA thioesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_17015</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the acyl coenzyme A hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000025">
        <property type="protein sequence ID" value="TXD87372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016790">
        <property type="term" value="F:thiolester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040170">
        <property type="entry name" value="Cytosol_ACT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033120">
        <property type="entry name" value="HOTDOG_ACOT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11049">
        <property type="entry name" value="PTHR11049"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51770">
        <property type="entry name" value="HOTDOG_ACOT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HotDog ACOT-type" evidence="4">
        <location>
            <begin position="8"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD87372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="184" mass="20746" checksum="45A60CE666EE1645" modified="2019-11-13" version="1">MTDFKTVEASVINISELMQPSHSNFGGKIHGGYILNLMDQIAFACASKHSETYCVTASVDTVDFLNPIDIGELVTMKASINFVGHTSMVVGIRVESENIRTGKVKHCNSSYFTMVAKDDHGNSVNVPGLILNDKNEVKRFLKAIKRTQTKRMRKSEFDKASFSYENYMEELKQHNVKIELPDKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCE3</accession>
    <name>A0A5C6ZCE3_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA small subunit methyltransferase I</fullName>
            <ecNumber evidence="6">2.1.1.198</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">16S rRNA 2'-O-ribose C1402 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">rRNA (cytidine-2'-O-)-methyltransferase RsmI</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">rsmI</name>
        <name evidence="8" type="ORF">ESY86_18255</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>cytidine(1402) in 16S rRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(1402) in 16S rRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42924"/>
            <dbReference type="Rhea" id="RHEA-COMP:10285"/>
            <dbReference type="Rhea" id="RHEA-COMP:10286"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74495"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.198"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the methyltransferase superfamily. RsmI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.198" evidence="6"/>
    <dbReference type="EMBL" id="VORO01000030">
        <property type="protein sequence ID" value="TXD87076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070677">
        <property type="term" value="F:rRNA (cytosine-2'-O-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000453">
        <property type="term" value="P:enzyme-directed rRNA 2'-O-methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd11648">
        <property type="entry name" value="RsmI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01877">
        <property type="entry name" value="16SrRNA_methyltr_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008189">
        <property type="entry name" value="rRNA_ssu_MeTfrase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018063">
        <property type="entry name" value="SAM_MeTrfase_RsmI_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46111">
        <property type="entry name" value="PTHR46111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005917">
        <property type="entry name" value="MTase_YraL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00096">
        <property type="entry name" value="TIGR00096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01296">
        <property type="entry name" value="RSMI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TP_methylase" evidence="7">
        <location>
            <begin position="3"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD87076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="223" mass="25034" checksum="42767768776708E8" modified="2019-11-13" version="1">MSKLYIVPTPIGNLKDMTYRAVEVLKEVDLILAEDTRTSGKLLKHYEIGTQMQSHHMHNEHQMVDNLVQKIKNGMRIALISDAGTPAISDPGFLLTRACVENNIEVDCLPGATAFVPALVNSGLPNDKFVFEGFLPVKKGRQTRLLLLADEPRTMIFYESPHKLIKTLSHFCEYFGEDRALSVSRELTKLYEETIRGTAKVVLEHYTNKPPKGEIVIVVSGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCK0</accession>
    <name>A0A5C6ZCK0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Lacal_2735 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_16610</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000023">
        <property type="protein sequence ID" value="TXD87515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="75" mass="8681" checksum="0C66146E06B93AF0" modified="2019-11-13" version="1">MNTHFCKVGNVRPNLSKRFSLKDLEEKYIKFTEDAYNAMHNDANLSDTLYHEASKLRDQILNLKGTNPNDFDAAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCV7</accession>
    <name>A0A5C6ZCV7_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">Glutamate racemase</fullName>
            <ecNumber evidence="2 7">5.1.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 8" type="primary">murI</name>
        <name evidence="8" type="ORF">ESY86_14650</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Provides the (R)-glutamate required for cell wall biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>L-glutamate = D-glutamate</text>
            <dbReference type="Rhea" id="RHEA:12813"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:29986"/>
            <dbReference type="EC" id="5.1.1.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the aspartate/glutamate racemases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.1.3" evidence="2 7"/>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008881">
        <property type="term" value="F:glutamate racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00258">
        <property type="entry name" value="Glu_racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015942">
        <property type="entry name" value="Asp/Glu/hydantoin_racemase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001920">
        <property type="entry name" value="Asp/Glu_race"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018187">
        <property type="entry name" value="Asp/Glu_racemase_AS_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033134">
        <property type="entry name" value="Asp/Glu_racemase_AS_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004391">
        <property type="entry name" value="Glu_race"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21198:SF2">
        <property type="entry name" value="PTHR21198:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01177">
        <property type="entry name" value="Asp_Glu_race"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53681">
        <property type="entry name" value="SSF53681"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00067">
        <property type="entry name" value="glut_race"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00923">
        <property type="entry name" value="ASP_GLU_RACEMASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00924">
        <property type="entry name" value="ASP_GLU_RACEMASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0133">Cell shape</keyword>
    <keyword evidence="6 7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="5 7 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="10"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="42"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="74"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="184"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="7">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="7">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD87907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="260" mass="28636" checksum="045D27945FC65ACA" modified="2019-11-13" version="1">MSTQPIGIFDSGIGGTSIFKEIHELLPHENTIYLADSKNAPYGNKSQDEILQLSIKNTELLLHRNCKLIVVACNTATTNAIDYLRLNYGVPIIGIEPAIKPAALNTKTKAIGILATKGTLSSALFHKTTDLYKRDIAVIEQVGDGIVPLIEAGKTDTIEMKALLERYLKPMVAANIDYLVLGCTHYPYLIPMLSNLLPKEVTIIDSGRAVAKQTKSVLEQYGLFNTTSVTAKNHFYTNTNTEVLRHILDNNHAIVEVLDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCW2</accession>
    <name>A0A5C6ZCW2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA mismatch repair protein MutS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_17415</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000026">
        <property type="protein sequence ID" value="TXD87339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS_family"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="PTHR11361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="163"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="267"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_MISMATCH_REPAIR_2" evidence="4">
        <location>
            <begin position="360"/>
            <end position="546"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD87339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="555" mass="63570" checksum="FB310AC05C051B65" modified="2019-11-13" version="1">MNWFLGVLIILVVVVFLTNNIRIKKRRLKILNQFKRNWGKPKNLDEFHFSSIEEYFNNTANKDKAFHIISNRCAADLDINDVFEVIDRTASKIGQQYLYYKLRTIESRSRLLAFNDLTLLFEGNESLRLKIQLELTKINTNGSYCFEELVTSKPLEKPKYIGLIYALSMLSFLLSILGFFVPLFFIVLIPIFALNMVFHYKNKWNISSYLDGISQLSKTIEVSKNIAAFPEIKKKFTDTRFIKNVEQIKLKSAFISFDKDLGNEFAIVFWLVSEFIKVLFNLEYLIFYSFTDSIANKRAELKQMFHFIGEIDAAISTASLKASDHNICNPIFTDEKKMAFTEISHPLINNCVVNNLTLVSHSLLLTGSNMSGKTTFIRSIAINSILAQSLNICFAKSYTAPFFKVYTSIRISDDVLESTSYYLEEVLTIKKLIEASQSDQPCLFVLDEIFKGTNTVERISGGKAILSYLNKGNNMVLVSTHDIELTVMLSNKKFNLYHFSEQIASNELKFDHKLKAGKLKSRNAIRILELYDYPSEIIDDAKATESATFDPSPNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDP0</accession>
    <name>A0A5C6ZDP0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Diphosphomevalonate decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_14730</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD88003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005935">
        <property type="entry name" value="Mev_decarb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041431">
        <property type="entry name" value="Mvd1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18376">
        <property type="entry name" value="MDD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015950">
        <property type="entry name" value="Mev_P_decrbx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="SSF55060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MDD_C" evidence="4">
        <location>
            <begin position="209"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF18376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD88003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="362" mass="40855" checksum="84EF33151FF3C08A" modified="2019-11-13" version="1">MTVNEFLPKPYPIAIANGSITCAAPSNIALVKYWGKKKDQIPENPSISFTLSACKTITTLHYKKKKDQDQFSFDIYLDGIPKPDFKPKIETFFRRIEMYVPFLKTYHFEIETSNTFPHSSGIASSASGMGALALCLVQLEQKLNAENAEESNYKKASFLARLGSGSACRSLEGELIVWGEHAKIEGSSDNFGTKYPYEVHEHFKDYQDVILLVDKGEKQVSSTLGHNLMHEHPYAERRFEQAHEHLSKLIDIFKTGNLDRFVAIVESEALTLHAMMMTSMPYFILMKPNTLHIINAIWKFRQNTGSKVCFTLDAGANVHLLFPKQEKDSVLKFIESDLAKFCQNGHYINDQLGLGAELLGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDQ6</accession>
    <name>A0A5C6ZDQ6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Crp/Fnr family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_14185</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="1">
        <location>
            <begin position="36"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="190" mass="22385" checksum="494E2E315525B83C" modified="2019-11-13" version="1">MKIHKIKEAFDPYFQESLENWEKFASLGKLIHCHKGEILKRPHDIEKHFNLILSGSGSIHLWNKNNYKCVDLAYEFDFFGDYMSYMTQQPSPLETIMIEDSELLQFSYHNFQNMLAESKRGEKITRIMADFAFISKQQQQIDLLTKTAFERLQQLKIQVPKLLERTPKKYISSYLGITPQSLSRIIKAFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDY9</accession>
    <name>A0A5C6ZDY9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribonucleoside-diphosphate reductase</fullName>
            <ecNumber evidence="4">1.17.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_18400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Genetic information processing; DNA replication.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ribonucleoside diphosphate reductase small chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.17.4.1" evidence="4"/>
    <dbReference type="EMBL" id="VORO01000031">
        <property type="protein sequence ID" value="TXD87030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00326"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004748">
        <property type="term" value="F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009263">
        <property type="term" value="P:deoxyribonucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01049">
        <property type="entry name" value="RNRR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.620.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012348">
        <property type="entry name" value="RNR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033909">
        <property type="entry name" value="RNR_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030475">
        <property type="entry name" value="RNR_small_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000358">
        <property type="entry name" value="RNR_small_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23409">
        <property type="entry name" value="PTHR23409"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00268">
        <property type="entry name" value="Ribonuc_red_sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00368">
        <property type="entry name" value="RIBORED_SMALL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD87030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="326" mass="38150" checksum="6948F8ACDA4996DA" modified="2019-11-13" version="1">MSQITEPILQENKDRFVIFPIKHHDIWEWYKKSEASFWTAEEIDLHQDLSDWKNKLNDDERYFIKHILAFFAASDGIVNENLAENFVNEVQYSEAKFFYGFQIMMENIHSETYSLLIDTYVKDEEEKDLLFNAIENFPAIKKKADWALKWIDSPSFAERLIAFAAVEGIFFSGAFCSIFWLKKRGLMPGLTFSNELISRDEGVHADFAVHLHNKHLINKVPKARIREILVDALTIEREFITESLPASLIGMNAKLMSQYLEFVTDRLLVELECEKEYNTANPFDFMDMISLQGKTNFFEKRVAEYQKAGVMSKEDEKDKFSFDADF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE47</accession>
    <name>A0A5C6ZE47_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF3784 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017259">
        <property type="entry name" value="UCP037672"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12650">
        <property type="entry name" value="DUF3784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="104" mass="11800" checksum="789DF6184188B044" modified="2019-11-13" version="1">MLFVPIFFIILGIVIKYGKMHFLIAGYNTMTKAQQANYDIEGIATVFRNGMFGMALIMLLGIFCSALMEDESIKLYTFFIALAIGIPYLLIRSNSNKFKVKKDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE84</accession>
    <name>A0A5C6ZE84_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">KilA-N domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017880">
        <property type="entry name" value="KilA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018004">
        <property type="entry name" value="KilA_N/APSES_HTH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04383">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01252">
        <property type="entry name" value="KilA-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51301">
        <property type="entry name" value="KILA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KilA-N" evidence="1">
        <location>
            <begin position="5"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="295" mass="34062" checksum="C5021A0FCAF1117E" modified="2019-11-13" version="1">MAKRNSIIVEGTEINITSLKEEDYISLTDMAGSKDDDSRAADVIKNWIRNRSTIEFLGTWESLYNKDFKVVEFDHFRKEAGLPTFTMSVSNWVESTNAKGIFSVKGRYGGTYAHRDIAFEFGSAISPIFKLHIIKEYQRLKEIETDKYGLEWDVRRILSKTNYKIHTDAVKKHIIPKTRYSAAKEWLEYADEADLLNIALFGCTAKQWRELNPTKVLNGENIRDMASINELAILSNLESLSSTLINNNITKKNRLKILIDTVREQRETLDKIDIIKSLKKNSNRTFIDAKRKLKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE88</accession>
    <name>A0A5C6ZE88_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphate transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_18385</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the inorganic phosphate transporter (PiT) (TC 2.A.20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000031">
        <property type="protein sequence ID" value="TXD87027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001204">
        <property type="entry name" value="Phos_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11101">
        <property type="entry name" value="PTHR11101"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01384">
        <property type="entry name" value="PHO4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="41"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="153"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="189"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="255"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="316"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="467"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="497"/>
            <end position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD87027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="765" mass="84239" checksum="07B5CB93D67ADF87" modified="2019-11-13" version="1">MENVYIYMLIALAFLAVADLVVGVSNDAVNFLNSAIGSKAVSFRTIIIVASLGVALGAMSSSGMMEVARKGIFNPGEFMFDEIMIIFTAVMITDILLLDFFNTLGMPTSTTVSIVFELLGASVCVALLKISASDSETFLDLGNYINNEKAIEIIVGILLSVVIAFTIGAIIQFLSRLLLSFKFESKPDYYGAIFSGLATTSILYFILIKGIKNASFMNDTVQDFIGDHPLQLIGLSFLVLTILSYLFISFTKKSIYVVIIIIGTFALAVAFAGNDLVNFIGVPIAAFNSYEAWSVSGSLPSEYAMDALNQPVGTKPILLLIAGLIMVLTLWFSTKARAVVKTSVDLSRQDNVKERFEPNFLSRTIVRGSIAASEGFNKLFSKTGKTYIDKQFEKPTQVIASKTEDQPAFDLVRAAVNLMVASVLISVATSMKLPLSTTYVTFMVAMGTSLADRAWGSESAVYRVAGVLNVIGGWFFTAFSAFLAAAIMAVILYYGRAYALTGLLVLAILLLVKNYIGHRKETKEQKEVDSLERAESSSTQGVIIESAKNIANVVKRGNKIYTGAINGLATQNHKTLKKNKKQVAKLSNEIDDLRDNIFYFIKNLEEPSMSASNFYINILGYLQDISQSLEFISKMSYKHVNNNHKKLKFSQIKELKEIDEVMETLFANTKNAFDAESFEEIGIVLTEKQKVLNMVNQKITKQVERTRTEESSPKNTTLYFSLLLETKDLLNATMNLLEEYYTAHDSKVEPARLPDTNEDSTPSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEI6</accession>
    <name>A0A5C6ZEI6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cation transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_12715</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036837">
        <property type="entry name" value="Cation_efflux_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160240">
        <property type="entry name" value="SSF160240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="SSF161111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="86"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="152"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="180"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD88375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="303" mass="34083" checksum="7994B2AAAEBEBFE2" modified="2019-11-13" version="1">MDHSHNHGHSPSELSGRNLVISIFLNIIITIAQVIGGLLSGSLALLSDALHNFSDVLSLLISYIANRFSKKEASLKKTFGYKRAEILAAFINAVTLIIVAVLLIIEAIKRFQNPQIIDSNLVIWLAIIAILGNGFSVLLLKKDAKSNMNMKSAYLHLITDMMASVAVLIGGLLMKYYQMFWVDSVLTLAIAIYLIVVGYDLLKNSYKVLMLFTPDTIEIDDIVNVVQQIEVIKNVHHVHIWQLNEDEIHLEAHIDFNEDIQLSQFNEVLHEVEALVYKKFGINHLNLQPEFGKNDTKDIIVQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEQ7</accession>
    <name>A0A5C6ZEQ7_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Tryptophan synthase beta chain</fullName>
            <ecNumber evidence="11">4.2.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11 13" type="primary">trpB</name>
        <name evidence="13" type="ORF">ESY86_16360</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine = D-glyceraldehyde 3-phosphate + H2O + L-tryptophan</text>
            <dbReference type="Rhea" id="RHEA:10532"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.2.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 11">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 5/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 11">Tetramer of two alpha and two beta chains.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the TrpB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.20" evidence="11"/>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00044"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004834">
        <property type="term" value="F:tryptophan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06446">
        <property type="entry name" value="Trp-synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00133">
        <property type="entry name" value="Trp_synth_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006653">
        <property type="entry name" value="Trp_synth_b_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006654">
        <property type="entry name" value="Trp_synth_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023026">
        <property type="entry name" value="Trp_synth_beta/beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001413">
        <property type="entry name" value="Trp_syn_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00263">
        <property type="entry name" value="trpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00168">
        <property type="entry name" value="TRP_SYNTHASE_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 11" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="10 11 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="8 11" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="PALP" evidence="12">
        <location>
            <begin position="55"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="11">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TXD87628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="393" mass="43167" checksum="1DE669415B0754CE" modified="2019-11-13" version="1">MTYNINEKGYYGEFGGAYIPEMLYPNVEELRLNYLKIMAEPSFKEAFDQLLKDYVGRPSPLYFAKRMSAKYKTKIYLKREDLNHTGAHKINNTVGQILMAQRLGKTRIIAETGAGQHGVATATVCALMGMECIVYMGEIDIARQAPNVARMKMLGAKVVPALSGSRTLKDATNEAIRDWINNPVDTHYIIGSVVGPHPYPDMVARFQAIVSEEIQWQLKEKEGTEKPTYVVACVGGGSNAAGAFYHYLEDTDVKLIAVEAAGKGVDSGESAATSILGKEGIIHGSKTLLMQTKDGQITEPYSISAGLDYPGVGPMHAHLYKTGRAEFMAITDDDAMLAGLELSKTEGIIPAIETAHSLAIFKYKTFKPEDIVVINLSGRGDKDLQNYIEYFDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEU4</accession>
    <name>A0A5C6ZEU4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glycoside hydrolase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_16100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000021">
        <property type="protein sequence ID" value="TXD87673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036156">
        <property type="entry name" value="Beta-gal/glucu_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006101">
        <property type="entry name" value="Glyco_hydro_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006103">
        <property type="entry name" value="Glyco_hydro_2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006102">
        <property type="entry name" value="Glyco_hydro_2_Ig-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006104">
        <property type="entry name" value="Glyco_hydro_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021720">
        <property type="entry name" value="Malectin_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00703">
        <property type="entry name" value="Glyco_hydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02836">
        <property type="entry name" value="Glyco_hydro_2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02837">
        <property type="entry name" value="Glyco_hydro_2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11721">
        <property type="entry name" value="Malectin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00132">
        <property type="entry name" value="GLHYDRLASE2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49303">
        <property type="entry name" value="SSF49303"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_2_N" evidence="6">
        <location>
            <begin position="30"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_2" evidence="4">
        <location>
            <begin position="189"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_2_C" evidence="5">
        <location>
            <begin position="299"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="domain" description="Malectin" evidence="7">
        <location>
            <begin position="697"/>
            <end position="853"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF11721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD87673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="870" mass="99593" checksum="CEB31D27E94EDB86" modified="2019-11-13" version="1">MKAQITPIKKLSYLVLWFVLFSFFGHGQKKSINAGWQFKLDKDASVWETINIPHTWNLKDAFDDEAGYYRGIGHYKKQVFFAESDAAKVHYLRFKGVNQDAKITVNGNLVGTHQGGYTAFTFNISAFLNFGAYNLIEVIVDNSHNEDIPPLDADFTFFGGIYRDVELLSKPKQHLALTDFSSEGFYVNYPSVSEEKAQLEVTARIDNFEDAQSTSQLRLEVLDANDSLVLSENENFKFTAIGALEKSIKFSDLKNPRLWSPERPYLYQLKIVLLDDQGVVLDRKTQQIGFRWVSVDASKGFYLNGKPYKLIGVNRHQDYDAYANAVPMALQKQDIQLIKDMGANVLRFAHYPQAQELYKLCDQLGILVWTEIPIVNKITNTKAFFDTALKMQEEQIKQYYNYPSVVMIGYMNEIFLRMDFDKKTPQAEKDQMKTHTYDLAEQLEKLTREKAPHHITVMALHYNELYNETKIADLPMLVGWNLYFGWYYETIADLGVFLDEQHQRFPNRPIMISEYGPGADVRVSAAQPERYDYSQQYQLKLHSSYVEQVQARDFVAGMTAWNFADFASEFRGETIPHINQKGLVTNNRVPKEIYYWYQAVLLKNTPVVHIANYQTDLTLFDNAPYEMTLFSNQASAKLSVNNAFFKEVTFNAGIARVLVPFTDGLNTLSLETASVIDEATFQVRRIESLKNEELKSFAINIGASIDFKDLETGVTYLADRPYKDGLYGYDSQSGKCERKLLANNIKNSNLEAVYQHVLVDCSRYKVAIPDGSYKVTLYFVEPQQTNQEHVIFNLNRQAEASEEKEQRIFDVLLNGTVMVSSLNLAKEYPNKYGVQHSFEIDILNNEGLTLTLKPLEGAPVISGILIETLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEZ7</accession>
    <name>A0A5C6ZEZ7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Aconitate hydratase</fullName>
            <ecNumber evidence="7">4.2.1.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_17420</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.3" evidence="7"/>
    <dbReference type="EMBL" id="VORO01000026">
        <property type="protein sequence ID" value="TXD87340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003994">
        <property type="term" value="F:aconitate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047780">
        <property type="term" value="F:citrate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006250">
        <property type="entry name" value="Aconitase_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00415">
        <property type="entry name" value="ACONITASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="SSF53732"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01342">
        <property type="entry name" value="acon_putative"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aconitase" evidence="5">
        <location>
            <begin position="9"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="domain" description="Aconitase_C" evidence="6">
        <location>
            <begin position="511"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD87340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="656" mass="71649" checksum="560FDD8A48EE54A0" modified="2019-11-13" version="1">MKAYNVAQKLIDSHLVIGEMIPGSEIGIKIDQALLQDATGTLVQLELEAMGLKKAKTEVAVQYVDHNLLQTDFKNADDHLFLLSGAQRFGLWYSRPGNGVSHPVHMERFGKPGKTLVGSDSHSCAAGSLGMLAIGTGGLDVAAAIAGEPYFVTMPKVMGVKLTGKLPDWVSAKDIILEMLRRHGVKGGVGKILEYYGDGLKNLSAMDRHVIANMGAELGATTSVFPSDDETKRFLRSQAREEDWIELVADEGCNYDLHEEIRLDELVPLIAQPTSPGNVVPVSEVAGKPIGQVVIGSSANPGLRDFWMAGAIVKDRSIDNEVSFDINPTSRQIIQNMIDNRAFANLIKAGARFHQSGCMGCIGMGQAPASDTISLRTMPRNFPSRSGTEDDQVYLCSPETAAASALTGKITDPRGLEKLFGMSYPQYVSPEMEIINTQLLVAPLEDGSQIELKKGPNIKALPHIDPLEDNYEVPVLLKMGDNVSTDEILKAGAEVLPFRSNLPEISKYTFTVIDDSFYDRAMESKSQHGGHIVVAKENYAQGSSREHAALAPKYLGQVAVIALSYARIAWQNLANFGVLPLEFITIEDYDKIEQGDTVSFKNLRNDIKDRNPIKVKVSNDSGKKLEFEVKHTLSDRQINMLLKGGIINEFKAKLNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFA6</accession>
    <name>A0A5C6ZFA6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">T9SS type B sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03603">
        <property type="entry name" value="CLECT_VCBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026341">
        <property type="entry name" value="Bac_Flav_CTERM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001304">
        <property type="entry name" value="C-type_lectin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016186">
        <property type="entry name" value="C-type_lectin-like/link_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034007">
        <property type="entry name" value="CTLD_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044023">
        <property type="entry name" value="Ig_7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19081">
        <property type="entry name" value="Ig_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="SSF56436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04131">
        <property type="entry name" value="Bac_Flav_CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50041">
        <property type="entry name" value="C_TYPE_LECTIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C-type lectin" evidence="1">
        <location>
            <begin position="146"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="813" mass="88486" checksum="C3ACA51791FBE2F5" modified="2019-11-13" version="1">MFRKIKISIAILSTIFLSILNGKTQDTPPQIVVSGNQGYCADAPIPIVSSVSIADADAGDDTLDEVFIQIAEGYAINQDLLSLNGSFPNITASWSVAEGKLTLNGPASFNEFTNAIGNVLFETTQTEFAEDKFISINLSAANYLPTTGHYYLYVADPGISWTQAENAAENQEFFGIQGYLATLTSAEEAQLAGEQSPGLGWIGASDAEIENTWKWVTGPEAGTVFWIGQANGTPQNGEFSFWNAGEPNNFNGNEDYAHITDPSIGNVGSWNDLPNTGDGNPGDPYYPKGYYVEFGGMPGDPEINLSASTAIIMPRIEVSASSNCENSVSQLSVTANTPRVLWYASETANTVINEGLTYEVQLNETTTFWVLPLFESCNTGTRIPFPITIFPTPDAVDIGITQCDDQAQDGLAVFNLNAYFEDITNGVSANRDIQYFEDAAQTIPIDGDAYTSVSNPQTVYAKIIDTSSGCSANAEIVLETTSEAVSPAFLEACDGLDETGLVNFDLSLATSQLLEGLSQDFEVTYYESYQDALDEFNVLPTNYTNTTPYNQMIYGRITDNGFCYTIAEVQLRVTALPNLEPDATVYYCLNSFPETIRLSGGVVGDIPNNYYYNWSTGETTINIEVNEIGSYTVEVTPVDGCPKTRTISVLPSSIAVIDEVVVNDLVDLNAINIIASGDGTYEYALNTFNGPYQSSNVFSNLSAGFYTVYVKDVKNDCGIVSQLVSVVGYPKFFTPNGDGYNDRWQLRGVSEQFQPNSKVFIFDRFGKLLKTLNTADQSWDGSFDGALLPSSDYWFSATLQDGRSFTGHFSLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFH7</accession>
    <name>A0A5C6ZFH7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">YihY/virulence factor BrkB family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_13615</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017039">
        <property type="entry name" value="Virul_fac_BrkB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30213">
        <property type="entry name" value="PTHR30213"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03631">
        <property type="entry name" value="Virul_fac_BrkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF035875">
        <property type="entry name" value="RNase_BN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00765">
        <property type="entry name" value="yihY_not_rbn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="40"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="146"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="195"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="227"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="260"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="291"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD88335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="326" mass="35780" checksum="E384617526BADFA6" modified="2019-11-13" version="1">MGTTSTGDRGHKAEKPSQIPKKGWKDIALRVKDRLTRDHVSIVSAGIAFYFFLAIFPALAAALSIYGLIMEPAEVEQQIGQLANVLPEQAHQMISNILEKQSEKSESSLGWSLVLSILISLWSANKGTKAVFQGVNITYDEIDERGFFKLTALTLLFTIGGIIIGLIAIAMVVAFPAIIDKIGLPSTLETIIQLLRWPILALIVIFALAAVYKVAPCRKSPEFKWTSWGAIIATVLWLAGSLLFSLYVNNFGSFDETYGSFAAVIILMLWFFLTGFIILLGAEINSEMEHQTSRDTTIGEDKPMGQRGGYHADHVAGKDKGNNESR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFJ1</accession>
    <name>A0A5C6ZFJ1_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">ATP-dependent DNA helicase RecG</fullName>
            <ecNumber evidence="3 6">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">recG</name>
        <name evidence="9" type="ORF">ESY86_15005</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the helicase family. RecG subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3 6"/>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004609">
        <property type="entry name" value="ATP-dep_DNA_helicase_RecG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045562">
        <property type="entry name" value="RecG_dom3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033454">
        <property type="entry name" value="RecG_wedge"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19833">
        <property type="entry name" value="RecG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17191">
        <property type="entry name" value="RecG_wedge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00643">
        <property type="entry name" value="recG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5 6" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="284"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="465"/>
            <end position="632"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD87976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="700" mass="80371" checksum="61892D342EFC2926" modified="2019-11-13" version="1">MSVNLQTPIDYLKGVGPQRADLLRSELGIHTYQDLLNLFPNRYLDRTQYYKINQLQRNSAEVQIIGKVVGFQEIAQKRGKRLVAKFQDDTGIMELVWFRSQKWIRDNIKPNVPYVIFGKVNWFNGTFSMPHPEMEVLQEHENNLRSSMQAVYPSTEKLSNKGVTNKVLNKIMQSLFLETNGRFVETLHEPLLDELKLMRKSEALFNIHFPKNQELLAKAEFRLKFEELFYIQLQLILKNLIHKAKIKGFNFDSVGTYFNTFYKNHLPFDLTNAQKRVLKEIRQDLGSNAQMNRLLQGDVGSGKTIVAFMSMLMALDNGFQACLMAPTEILAIQHFQGLGELAAEMDISIKLLTGSSKTKQRKIIHETLENGELQILIGTHALLEDKVKFQNLGLAIIDEQHRFGVAQRSKLWEKNSIPPHILVMTATPIPRTLAMSVYGDLDISVIDELPPGRQAIKTVHRFDKNRLKVMRFMRDEIEKGRQIYVVYPLIQESEKMDYKDLMDGYESIVRDFPQPKYQISIVHGQMKPADKDFEMQRFVKGETQIMVATTVIEVGVNVQNASVMIIESSERFGLSQLHQLRGRVGRGAEQSYCILMTGHKLSQDSKVRLETMTRTSDGFEIAEVDLRLRGPGDIMGTQQSGILNLKIANIIKDKDILQSARFYAKRILSNDPSLVQPEHQAILNTYRALGKYKNIWNYIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFQ7</accession>
    <name>A0A5C6ZFQ7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF177 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_13050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003772">
        <property type="entry name" value="YceD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02620">
        <property type="entry name" value="YceD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="180" mass="21038" checksum="B55AC77F25DB8DE1" modified="2019-11-13" version="1">MKPLKDFTIPFVGLKVGTHHFDYQIDKKFFENFEYDDFQDVDIQADIVFEKKTTLLELLFKVKGMVTVNCDLTNEPYAQPINGEYKLVIKFGEDYNDEFEDILIVPHGEYEINVAQYIYETIILAMPAKRIHPGVEDGTLDSEILNKLEELRPKNLEEKEATSEEIDPRWNTLKKLLTDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG11</accession>
    <name>A0A5C6ZG11_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cupin-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15175</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="1">
        <location>
            <begin position="105"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="287" mass="34391" checksum="9A1AFFA8462B3E7D" modified="2019-11-13" version="1">MNLQLQDIPRVTNISKEDFIKHYFKPQKPVVIEHFIEDWPALNKWSLDYMKDIAGDKTVPLYDDRPVDYKDGFNQAHATMKMSEYVDLLKREPTKYRIFLWNVLKEIPELQKDYSYPDFGLRLMKSLPMLFFGGKNSHTFMHYDIDLANIFHFHFEGQKQIILFDQDQSKHLYKVPHSLITREDIDFSQPDFEKWPALKNAEGWECELHHGEVLYMPEGYWHYMKYLTPGFSMSLRAVARHPKTLGKAFYNVFVLRNFDNLMRRLKGQDWIDWKNEKAIARTNKQLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG32</accession>
    <name>A0A5C6ZG32_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">M61 family metallopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_13695</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024191">
        <property type="entry name" value="Peptidase_M61"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007963">
        <property type="entry name" value="Peptidase_M61_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040756">
        <property type="entry name" value="Peptidase_M61_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05299">
        <property type="entry name" value="Peptidase_M61"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17899">
        <property type="entry name" value="Peptidase_M61_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016493">
        <property type="entry name" value="Glycyl_aminpptds"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022854167" evidence="1">
        <location>
            <begin position="19"/>
            <end position="594"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M61_N" evidence="4">
        <location>
            <begin position="23"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M61" evidence="2">
        <location>
            <begin position="282"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="3">
        <location>
            <begin position="491"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD88237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="594" mass="67305" checksum="065C61B5AB8A880A" modified="2019-11-13" version="1">MRYFFGLVFIVFTLKLQAQVASNYTISFENAVQHEAQVKAEYSNLKSDTVTLSMSRSSPGRYALHEFAKNVYDVKVTNANGDTLTTTRPNPYSWQVTGHNGSINLSYTVFANHGDGTYAQVDETHAHLNMPVVFMYVPELSNQEIEVTFEPREDLNWKIATQLKQQQGNRYYARDLQYFFDSPTILANYKKRSFKVGDQNINLVLHDEEASEAQVDSYFEDLKKIVLEQRKVFGELPAYDYGEYTFLACYMPNATGDGMEHRNSTIVTSTTSLANGGIKDNIGTVAHEFFHCWNVERLRPQSLEPFDFSRANMSGELWFAEGFTSYYDDLSMVRSGVITPEAYIQGLVGTFNYVWTSPGRQFFNPIEMSYQAPFVDAAKSVDETNRENTFISYYSYGSSLGLALDLSLRAEGLNLDDYMKRMWQDFGKTNTFYTIEDLHQTLNTYAGTDFGDAFFSNSIYKSGMPDYEALLKQVGVVLETKDEIGFGAYVRDQVILSNPKMGTSAYSSGFQKGDTLLQLDAIRLDGSVSLNSVLSTFKVGDVIAIRYKRFGKEKKTNLTVQTERTYALSLIPSTDKAFTKKMEQGRGAWLKQSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG50</accession>
    <name>A0A5C6ZG50_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_16445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="17"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="169" mass="19387" checksum="777C6FAC14E1FEBB" modified="2019-11-13" version="1">MLPELAKVKGVHPGAILKRELKAQSLKGIELATSIGEHKQTISALLNKRRDINPKLSIKLSKHFNVEEDYFMLLQASHDVKKASQSELKKTPNIKTFRAVIFWDTTIDKIDWNKNKKAIIKRILERGNTNEIISFYGKKTISNAVKSIETRHMPAFEQNLIKHNVFVIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG56</accession>
    <name>A0A5C6ZG56_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sulfotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_09815</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000863">
        <property type="entry name" value="Sulfotransferase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00685">
        <property type="entry name" value="Sulfotransfer_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Sulfotransfer_1" evidence="1">
        <location>
            <begin position="27"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="329" mass="38800" checksum="EB4C411A9FCB3B34" modified="2019-11-13" version="1">MQYKTKVIEVFRFLNHIRFKRIEKNKNILIYGISRGGTTLLAETLVGLFNARLVWEPLFPFSDVRFDAINPFSINAYKKLGFGWSPHTNIANVSKLNTYFDRLFSLKVRNIRYLRFTNHKEFENSDHTVFKFCFANFMYPYFQERYKAKAIILLRHPFAIAASSLNFGDNFNWHKENYASWKYHDSQHSGKFFEGYDDKYELINSPFTLLVFQAVSQFAYAMENMDASNTIVVYYEDIVAQPEHVFEQLEHFFEIPLDESIFTRLVKKQSFSSQKGHTKKNPLDQLSKWKTKVPKEEIASALKIFEAFEFECYSDEILPLKHSTSSSIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG77</accession>
    <name>A0A5C6ZG77_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Calcium/sodium antiporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_15345</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004481">
        <property type="entry name" value="K/Na/Ca-exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10846">
        <property type="entry name" value="PTHR10846"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00367">
        <property type="entry name" value="TIGR00367"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="79"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="171"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="207"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="237"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="265"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="299"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="Na_Ca_ex" evidence="6">
        <location>
            <begin position="4"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="Na_Ca_ex" evidence="6">
        <location>
            <begin position="172"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD87884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="318" mass="34376" checksum="C4D6C36DE4696779" modified="2019-11-13" version="1">MILSACLVVLGFALLIKGADWMVNGSTMLAKKHRIPDLAIGLTIVAFGTSAPELVVNTVASFEGHSDIVLGNVIGSNNFNLFLILGVVGLIYPITVQSSTVQREIPISFLAAVVFLLLANGYLFYDNIGLSRVDGLVLLLLFFLFLYYIYKQMRADVEVTETPKMEASSKKIWMLIALGLLGLIVGGKLIVDNAVAIASDMGVSEKIIGLTIIAAGTSLPELMTSVVAALKKNSDIAIGNIIGSNIFNILLILSVSSLVNPINFSAIFNMDIYLLLGGTLFLFLAMFTGKKKRLDRWESAILLITFVGYTTFLISKEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG89</accession>
    <name>A0A5C6ZG89_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DEAD/DEAH box helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_10710</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005580">
        <property type="entry name" value="DbpA/CsdA_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03880">
        <property type="entry name" value="DbpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="1">
        <location>
            <begin position="28"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="2">
        <location>
            <begin position="220"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="437" mass="48886" checksum="487F9E443F977014" modified="2019-11-13" version="1">MIYSIKNQQDILDKLNIEALNPMQEEAVSMIAETTNTILLSPTGTGKTLAFLLPLLKVLDPDSQEVQALIIVPSRELAIQIEQVVRSMGSGYKVNAVYGGRPMSKDKIEIKHSPAILIGTPGRVLDHFDSDRFSKSSIKTLILDEFDKSLEDGFEEEMKAIIGQLPSINKRILTSATQGITVPGFVRLDKPYTIDYLKEKTESRLAIKTVVSADKNKLKTVLDLLQHLGSEQGIIFCNLRDSIEQVSGYLERNKVTHACFSGGMEQQDRERALIKFRNGSSQVLVATDLAARGIDIPEMNYIIHYELPRHEEEFIHRNGRTARVNATGTAYVLKWAKEALPEFIKQSKAVNISKKAPHKPQFWETLFISGGRKDKISKGDIAGLFIKQGGLEKDQLGSIELKQDCAFVAVPLKLAETLVEKLNNSRLKKKKVRIYVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGD3</accession>
    <name>A0A5C6ZGD3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_12080</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="76"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="105"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="145"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="183"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="236"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="277"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="303"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="330"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="361"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="402"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="11"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD88697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="436" mass="47777" checksum="1428CBB1B356DDA1" modified="2019-11-13" version="1">MKTKLKSTLTIILLILAGEAVFILPFVLQRIFRPTFLETFAINNTQLGSCFSVYGIVALFSYLFGGPLADKFRPHVLMSVALILTASGGFYLASYPSLLNLHILYGFWGFTTIFLFWAAMIKATRIWGGKNRQGIAFGFLDGGRGLVAALFGSAGVFVFSLYISKDIEFTTLQERQIAFKQVILYASIVISVIGVLVFFFLKNLQSSTADSDLSVETMAANSQTLTIDNFKAVMQYRAVWLLMIIILCAYFGYKMTDIFSLYANQVMLYDEIKSAKIGTYLLYMRPIIGVVIGGLADRTRATLWIVIGFVLMVLTSLLFASGIVNSNTTLLFVLSIGIMALGVYSARVLYFAVLEEAKIPLAITGTAVGFISVVGYTPDIFAGPLMGYFLDANPGAVGLEHTFGLMVGFSVVGLVASVVLWRRSGKATVITKQKSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGE6</accession>
    <name>A0A5C6ZGE6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">LysR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_13285</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_066434165.1">
        <property type="nucleotide sequence ID" value="NZ_VORO01000015.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="1">
        <location>
            <begin position="24"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="112" mass="12794" checksum="90CFCA7515D0C91B" modified="2019-11-13" version="1">MKQLKIKCWIEADGEKYYGPGPHELLKQIQKEGSLSKAAEKMHMSYKKAWAMVQRLNQFSEEALVILKKGGQHGGGAEVSPYALEIMKEYDTLQLKVKQLIDQEGKLLKFLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGQ2</accession>
    <name>A0A5C6ZGQ2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_12935</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="370" mass="41959" checksum="F4BC4AB4850BF694" modified="2019-11-13" version="1">MKYAYLLILSILFFNCKNEPKNSSEAKKDISEVVENTASDSLIYPEEKHFKSMRQVTFGGDNAEAYWSFDDQQLVFQSNNKDWGVNCDQMFLMDRDDTFKDGKPPMISTGMGRTTCAYFLPDNKHIIYASTHLGDKACPDTPLRKNGKYIWPIYDSYDIFVADLEGNIVNQLTNEVGYDAEPTVSPKGDKIVFTSTRSGDLELYTMNIDGSDVKQITNELGYDGGAFFSPDGTKLIFRSSRPKTEKEIKDYKDLLAEGLVEPTEMELYICNADGSEMRQLTYLGNANWSPFFHPSGNKILFSSNFEAERGFPFNLYLIDLDGKNLERVTHSETFDAFPVFSNDGKYLAFSSNRNNGGGRDTNLFIAEWQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGT2</accession>
    <name>A0A5C6ZGT2_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Methionine--tRNA ligase</fullName>
            <ecNumber evidence="16">6.1.1.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Methionyl-tRNA synthetase</fullName>
            <shortName evidence="16">MetRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16 20" type="primary">metG</name>
        <name evidence="20" type="ORF">ESY86_15325</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 16">Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 16">
            <text>ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl-tRNA(Met)</text>
            <dbReference type="Rhea" id="RHEA:13481"/>
            <dbReference type="Rhea" id="RHEA-COMP:9667"/>
            <dbReference type="Rhea" id="RHEA-COMP:9698"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78530"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="16">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="16">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 16">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 16">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 16">Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.10" evidence="16"/>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004825">
        <property type="term" value="F:methionine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006431">
        <property type="term" value="P:methionyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07957">
        <property type="entry name" value="Anticodon_Ia_Met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00814">
        <property type="entry name" value="MetRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02800">
        <property type="entry name" value="tRNA_bind_EcMetRS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00098">
        <property type="entry name" value="Met_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041872">
        <property type="entry name" value="Anticodon_Met"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004495">
        <property type="entry name" value="Met-tRNA-synth_bsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023458">
        <property type="entry name" value="Met-tRNA_ligase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014758">
        <property type="entry name" value="Met-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015413">
        <property type="entry name" value="Methionyl/Leucyl_tRNA_Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033911">
        <property type="entry name" value="MetRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029038">
        <property type="entry name" value="MetRS_Zn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002547">
        <property type="entry name" value="tRNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45765">
        <property type="entry name" value="PTHR45765"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19303">
        <property type="entry name" value="Anticodon_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09334">
        <property type="entry name" value="tRNA-synt_1g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01588">
        <property type="entry name" value="tRNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01041">
        <property type="entry name" value="TRNASYNTHMET"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57770">
        <property type="entry name" value="SSF57770"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00398">
        <property type="entry name" value="metG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00399">
        <property type="entry name" value="metG_C_term"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50886">
        <property type="entry name" value="TRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="15 16 18" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="12 16 18" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 16" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 16 18" id="KW-0436">Ligase</keyword>
    <keyword evidence="9 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 16 18" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14 16 18" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13 16 17" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7 16 17" id="KW-0820">tRNA-binding</keyword>
    <keyword evidence="11 16" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="TRNA-binding" evidence="19">
        <location>
            <begin position="595"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="16">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="16">
        <location>
            <begin position="345"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="348"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="RuleBase" id="RU363039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="PROSITE" id="PS50886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="TXD87841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="696" mass="78426" checksum="73EC6C89DCAD96CC" modified="2019-11-13" version="1">MCTFVPCKTIIKMSKRYTITAALPYTNGPIHIGHLAGVYVPADIYARYKRLTGNDVAFICGSDEHGVPITIKAKNEGVSPQDIVDKYHANIKKSFEDFGITFDNYSRTTAKIHHDTAQEFFKTLYDKNEFVEEVTEQLYDEEANQFLADRFVTGTCPKCGNEEAYGDQCESCGSSLNATDLINPKSAITGNVPSLKKTKHWFLPLNKHEQFLKDWILKGHKKDWKPNVYGQVKSWIDDGLRPRAVTRDLDWGIPVPVPGGEGKVLYVWFDAPIGYISSTKEWAAREGKNWEDYWKDENTKLVHFIGKDNIVFHCIIFPSMLKAEGSYILPDNVPANEFLNLEGQKLSTSKNWAVWLPDYLLDFPNQQDVLRFALTANAPETKDNDFTWKDFQARNNNELVAIFGNFINRVVVLTNKYYDGIVPEASEFSVIDNKTIETLKAYPAVIESSIERYRFREASQELMNLARLGNKYLADEEPWKLVKTDEARTKTIMFVALQIASALAILSEPFLPFTSAKLKGILNVNAENDTQWQDVSAKDVLLPQGHHIGKGELLFSKIEDEAIETQLKKLEASKKSNKAANMKVETQKETINFEDFTKLDLRVGTIVSAEKMPKTKKLLVLKVDTGIDTRTIVSGIAESFTPEEVVGKQVTVLVNLAPRSLRGVESEGMILMTESADGQLVFVNPDTTVKNGLQIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGV9</accession>
    <name>A0A5C6ZGV9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADP-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10905</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041694">
        <property type="entry name" value="ADH_N_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045010">
        <property type="entry name" value="MDR_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43205">
        <property type="entry name" value="PTHR43205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16884">
        <property type="entry name" value="ADH_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="17"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="332" mass="36479" checksum="D0C2CA71D039DDD9" modified="2019-11-13" version="1">MKTKTIILKHRPEGKPKSSDFEFIDEELADLKSGEIQLKLKYVSVDPYLRGRMRDEKSYMPPFELDAPIASMVVAEVIETKNDDFKKGDVVTGMLPWKKEQISDGKNLTKIDDKNVPLTAYLGVLGLTGLTAYLGFTEIGKPKKGETLVVSGAAGAVGSIVGQLGKIMGCHVAGIAGTDAKVEKLKSKFGFDAGINYKTTENMRKAIAETCKDGVDIYFDNVGGEISDAVLYNINKFMRTINCGAIATYNETSVPRGVSVRPFLIKNSALMQGFIVSNYEAKFDEARKQLGKYLKEGKLTHEETIKEGFENIPEAFMGLFEGENTGKMVVKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGW9</accession>
    <name>A0A5C6ZGW9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GNAT family N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12285</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="150" mass="17446" checksum="7BD059B4D3881223" modified="2019-11-13" version="1">MDNLHLRPATASDKEICYRIKQLSLKPYVNTIWGWDEMVQLKAHNDHFSRSATTIIIYKNKPIGYYELVETNAHFILKNILIENQFQNLGIGNFVMQLLIENANALEKSIQLKVFKVNGKAQKLYSKLGFNVVEITEYHLKMQKNFEAIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGX7</accession>
    <name>A0A5C6ZGX7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_09170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027020">
        <property type="entry name" value="YnjB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029172">
        <property type="entry name" value="UCP029172_ABC_sbc_YnjB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="403" mass="45922" checksum="C52185544BF6A689" modified="2019-11-13" version="1">MKYFITCSLVLLLFSCGNEKKQAQTDYTEASWETITKDAKGQTLTMIMWIGDSKINAYMKGFVKPMVKKNYDINLEIVGGQGGQIIQMLMTELQANAETSNVDMLWINGETFYQLRQLDGLYGPWTSKLPNSKYIDFNNPFIGMDFQQPIEGYELPWGNVQMAMIYDSAKVENPPMTREGLLAFVKANPGKFTFDNQFTGLTFLKALLIDIAGGDDVLKGDFDEAKYHKYSQELWTYINELKPYLWRQGEVFPESVAQMHQLFASGELWFSMSNNDAEVDSKTSEGLFPETARAYVPDFGTIQNSHYLGITKLSGVKPAAMLVANFMVSPEAQLEKMRPTVWGDGTVLDMETLSEDMKAKFQNLPSRKRAPKRSEIQQKAHLELAPEYMIRLSEDFRKEIIEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHC4</accession>
    <name>A0A5C6ZHC4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nucleoid-associated protein ESY86_11910</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11910</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the YbaB/EbfC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043590">
        <property type="term" value="C:bacterial nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1310.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00274">
        <property type="entry name" value="DNA_YbaB_EbfC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036894">
        <property type="entry name" value="YbaB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004401">
        <property type="entry name" value="YbaB/EbfC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02575">
        <property type="entry name" value="YbaB_DNA_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004555">
        <property type="entry name" value="UCP004555"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82607">
        <property type="entry name" value="SSF82607"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00103">
        <property type="entry name" value="DNA_YbaB_EbfC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="107" mass="12042" checksum="62851202589F9371" modified="2019-11-13" version="1">MFGDMMGMMGKLKETQKKVEETKARMDNVLLDENSSDNKLKVTITANRTLKSISIDDELLQDKEMLEDYLILTLNKAIERASTVNETEIAAVAKEGMPDIPGMDLFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHI5</accession>
    <name>A0A5C6ZHI5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">T9SS type A sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_07550</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd06263">
        <property type="entry name" value="MAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04275">
        <property type="entry name" value="ZnMc_pappalysin_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045474">
        <property type="entry name" value="GEVED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000998">
        <property type="entry name" value="MAM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008754">
        <property type="entry name" value="Peptidase_M43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20009">
        <property type="entry name" value="GEVED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00629">
        <property type="entry name" value="MAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05572">
        <property type="entry name" value="Peptidase_M43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00137">
        <property type="entry name" value="MAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50060">
        <property type="entry name" value="MAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023078956" evidence="2">
        <location>
            <begin position="23"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="domain" description="MAM" evidence="3">
        <location>
            <begin position="510"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="529"/>
            <end position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="800" mass="85527" checksum="35D9A5B5319ECB82" modified="2019-11-13" version="1">MKNKITLTLLLFVALFSVSAQERECATMANLELRKQLDPGLESRMQQIEIFTQNKIEELQTSRIDGSVITIPVVVHVLYRNSTENISVAQIQSQLDVLNEDFRRTNTDADNVWSQAADAQIEFCLVSVDPNGNATNGITRKSTNRRNWGLNDEMKSAATGGVDPWNTSEYLNMWIVPQMLRPTGETILGYAQFPGGDAATDGCVMSYNYFGNTGAVSAPFDGGRTTTHEIGHYFNLRHIWGDSNCGNDLVNDTPTAATANYGCATGNFSCGSTDMVQNYMDYSDDSCMNLFTSGQKNRMRAVLAAGGARRSLALSDKCGAVAQPTCNDGIQNGDETGVDCGGSCTPCQTGNQYCASQGNSVNDEYISRVQVGSINKASGAQLYSDFTSTASDLNKGGNYTLTITPTWTGSTYAEGYAAWIDYNDDGDFTDSGEQIFSKAASTATPATGSFTVPSGASSGNKRLRVAMKYNGIPTACETFGYGEVEDYTVNITTGSNPPAGCANAIAAFPYSEGFEAGFGAWSQATDDDFNWTRRSGATPSSNTGPSSASQGTQYAFMESSTPNNPNKRAILVSPCFDLTGQNQASFSFDYHLYGTNAMGNLKLAISTNDGASWTTVWSKAGNQGNAWNTATVDVSAYAGNTIKLRFDGTTGTTWQGDMAIDAISLTNGAADKCAGVSPYNGSQSYAVGDKVTYQGNLFERSNSGWTNLGACGTARAIVEGSVDHLGLEISIYPNPVKGELLFVKSSAENLSFNIKTILGQQVSKGASTENGVDVSKLKAGMYFINIQNGDEVITKKFIKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHI9</accession>
    <name>A0A5C6ZHI9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribonuclease R</fullName>
            <shortName evidence="4">RNase R</shortName>
            <ecNumber evidence="4">3.1.13.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rnr</name>
        <name evidence="6" type="ORF">ESY86_12705</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates.</text>
            <dbReference type="EC" id="3.1.13.1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RNR ribonuclease family. RNase R subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.13.1" evidence="4"/>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008859">
        <property type="term" value="F:exoribonuclease II activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01895">
        <property type="entry name" value="RNase_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011129">
        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040476">
        <property type="entry name" value="CSD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013223">
        <property type="entry name" value="RNase_B_OB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001900">
        <property type="entry name" value="RNase_II/R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022966">
        <property type="entry name" value="RNase_II/R_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011805">
        <property type="entry name" value="RNase_R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17876">
        <property type="entry name" value="CSD2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08206">
        <property type="entry name" value="OB_RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00773">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00357">
        <property type="entry name" value="CSP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00955">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01175">
        <property type="entry name" value="RIBONUCLEASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="S1 motif" evidence="5">
        <location>
            <begin position="659"/>
            <end position="740"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD88374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="745" mass="84977" checksum="A53B6BE86419A8AA" modified="2019-11-13" version="1">MTKRKTRKPSNNKISNLTNTILSILKKDRNQNFNYKQIAAKIGVNDASSRNQIIKKLQQLKAKEEIEEVERGKFAIVNNNEYHTGRVDMASRGSGYIISDDFEDDTYISSNNMNKALHGDEVEFYVYKRKNRGKQEGEVTNIIKRAKSEYVGVIQLHKNYAFVVVDGNKMYTDIFVPISKINNAENGDKVLVALEEWPEKADSPNGKILEVLGKPGEHNTEMHAILAEYGLPLDFPPEIEAFADKIDTSITEEEIAKRRDMRKDLTFTIDPKDAKDFDDALSFTVLEDGLYEIGIHIADVSHYLTPDNVLDDEAYERATSVYLVDRVVPMLPEILSNNACSLRPNEEKYTFSAVFKINDKAEIMDQWFGKTVTYSDARFAYEEAQAIIENNLGLKASEVIKNPGKIDTTIPQEVAISGKEYKTTQEVAQATLKLDELAKIMRSKRMSAGAISFDKVEVKFNLDEEANPIGVFFKTSKDANKLIEEFMLLANKKVAEFIGKQDPKKTFVYRVHDEPDESKLAALQNVVGRFGYKLNLQDRKSVSNSLNNLLKEVNGKKEQNLVDTLTIRTMSKAEYTTRNIGHYGLAFDYYTHFTSPIRRYPDVMVHRLLQHYLEGGKSANEDIYEDKCNHSSNMEGLATRAERDSIKYMQIRFMEDHKNEEFVGVISGVTDWGIYIEIIANKCEGMVSVRDMKDDHYQFDEDHYAVIGKKNNIMYQLGEEVVVKVKSTDLVKKHLDFTLIGKHEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHK0</accession>
    <name>A0A5C6ZHK0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">T9SS type A sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07665</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023039215" evidence="1">
        <location>
            <begin position="24"/>
            <end position="1092"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1092" mass="118516" checksum="1A0A705DF4F1593A" modified="2019-11-13" version="1">MKLKITQPMLCLGLFLVSTSLFAQIVVSSVFPRRVTTKTEVTITGGTSFTNATNVILSEIDFGSKTASNGGTQLTFEITRTNTSATGDVAPTPLMIGSQLVYTGFFSPDNQVFIEYIGPTDRTLQASGGTNPVTRITEVFTNWDYNGNGYYKSSWYSSGTTSTWPNDRHDLLAYTYNGTTYSTGVDDQLLTDKGIPFTPQTFKAYSTNGIKGNPHGANFLAMADKIDGVLGSRILNDLVKATVYDVIIDGSNDNGLDLGTGITNFNRNANIRFFSGNAIVGALGDAIPDLLLTQIAQAGGSDIYYYADIEGNVVGRPINLSIPEESNTILYKWFLDLYRMDLSLPYDQSLPNQLSFGNNENRPFRMIALELDEFEIVATPITSPNYIGKINNINMQAGGTADLAFMAYNRAAFDIKSPKVDQFPVSRNVCKVPNTDGITFNAAASIDGGGTGASGETLQYQWYKNFAAITGATSDSYNLAAINGGSLGTYKVRIFNDFGAVDLPVTLAEGGTPTFWDGANWVLPAALTAAGVNVSDADRNLIFSEDYSENSNLEGCDCRVVAGRTVTIPMGQTLKLYNTITVEPEILAVPLVNPYIPAGQFTLANNASLIQTKDLSLIGNENSGSIRVQRLADNLHVNDYVYWSSPVAGFNINGIPGSSAYEWDPTVGNPEGSSGNWVSASGLIMAAGKGYIKKVTPAAGTATAFTNTFSGIPNNGPVTAVVRMSNGTLPAADDQHWNLIGNPYPSAINAVKFLNLTENNSIEGAIYLWTHHAAISSIPNPADSPFYQDFVYNYGDQYLTFNELGETPSAPTGETFNGNIAAGQGFFVRAVSDGNVTFKNELRHDTNEDSYDNTNFFRTDSEHNTADNTEKQLIWLSLVADNAVAVSTLLGYAENATYARDRMFDAQTNSDDFSIYSMIANDKMSIQGRPLPFETSDTVPLGIEIPQNGIYKIGIDNLQGSVFVDQAQAIYLEDTYLNLVHDLRATPYGFTAVTGAVNDRFVLRYTQDETLAVNESIASETFAFIKNNELQVRSSQNIESIQIYDLNGKQIATYELKGNNSAFNANFQFARGVYLAVITLDTDLLVKKKLIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHK1</accession>
    <name>A0A5C6ZHK1_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Type III pantothenate kinase</fullName>
            <ecNumber evidence="6">2.7.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">PanK-III</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Pantothenic acid kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">coaX</name>
        <name evidence="7" type="ORF">ESY86_09235</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>(R)-pantothenate + ATP = (R)-4'-phosphopantothenate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16373"/>
            <dbReference type="ChEBI" id="CHEBI:10986"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29032"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.33"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>NH4(+)</name>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
        </cofactor>
        <cofactor evidence="6">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="6">A monovalent cation. Ammonium or potassium.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 6">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 1/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the type III pantothenate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.33" evidence="6"/>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00241">
        <property type="reaction ID" value="UER00352"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004594">
        <property type="term" value="F:pantothenate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01274">
        <property type="entry name" value="Pantothen_kinase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004619">
        <property type="entry name" value="Type_III_PanK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34265">
        <property type="entry name" value="PTHR34265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03309">
        <property type="entry name" value="Pan_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00671">
        <property type="entry name" value="baf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="4 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0630">Potassium</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="94"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="6"/>
            <end position="13"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="117"/>
        </location>
        <ligand>
            <name>a monovalent cation</name>
            <dbReference type="ChEBI" id="CHEBI:60242"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD89221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="242" mass="26398" checksum="4D45068A58FD9165" modified="2019-11-13" version="1">MNLIIDVGNTRVKLAVFSQNALLFQQAILLKEFEFELEATLKAYPALKKAIIASVGKLAASQVALVKARLTALELSQDLNFPFTNLYKTPHSLGVDRIALVSASVFKFPNKNVLIIDAGTCITYDFINAQNQYLGGAISPGIRLRYESLHNHTAKLPLLPTTRPVALIGNATNSAIHSGVVNGISMEIDGILNDYHNNYSDLTVILTGGDAEFLSNQLKNGIFATSNFLLEGLNFILEYNTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHM2</accession>
    <name>A0A5C6ZHM2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Universal stress protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_11145</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal stress protein A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="2">
        <location>
            <begin position="2"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="Usp" evidence="2">
        <location>
            <begin position="148"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="277" mass="30707" checksum="FD1C7BC30B3FF22D" modified="2019-11-13" version="1">MNKIIVPIDFSEHSEYALQSAALLAKRYDAELLALHMLDLESDRLTDSSDEQNEKMIFFLGLAKKRFHSFLDKDYLEGISVTPIVKHFRVFSEISNVAEEHKADLIVMGSHGASGLSEVFVGSNTEKVVRNSKTPVLVIKQKPSTLNFETVVFASDFNDEAVSAYQKVLQLFQGFGSKVHLLNVNVPGQGFRSSAELEKRLANFLQKADGNLDKINDIHYVSDYSVEKGIHNFSNLVGADLIAIPTHGRKGLAHLFSGSISEDIANHSSLPVITFKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHM4</accession>
    <name>A0A5C6ZHM4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">FtsX-like permease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_12915</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="273"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="320"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="366"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="25"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="307"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD88414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="400" mass="44051" checksum="24DF75D630C1646A" modified="2019-11-13" version="1">MNFALYIAKRYLFSKSSNNAINIMTIIAASGTVIAAAALFIVLSGFAGLKTFSLEFSSFVDPDLKLFPSEGKSFLFTDAEKSEIQKIDAIEVYSKTIEERVILEFDDKQQIVTLKGVDENFTKVTAIDSMVYYGSWLDPEASQVVAGGGISNKLGFGILDFSKSLKIYVPKPGKGQITSIRGAFNSVTAYNVGVFDINEDLNNEVIFSDIETASYLVNYKKNQLSSIEFKLKDGANQAEVAQQIASIFGNKVKVKNRNQLNDALYKMLNTENVAVYLIFTLVIIIALFNVVGALIMMILDKKESLNTLFNLGTTTKDIRLIFFFQGSLMTVLAGVFGLIIGFVIVYLQQQFALVMITPSLPYPVEIQGINFVIVLATICTFGILASKLASQRISKNLVKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHY7</accession>
    <name>A0A5C6ZHY7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Dodecin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_10600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1660.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009923">
        <property type="entry name" value="Dodecin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025543">
        <property type="entry name" value="Dodecin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036694">
        <property type="entry name" value="Dodecin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39324">
        <property type="entry name" value="PTHR39324"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07311">
        <property type="entry name" value="Dodecin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89807">
        <property type="entry name" value="SSF89807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="66" mass="7352" checksum="85A8182578DE20AD" modified="2019-11-13" version="1">MAVLKVIEIMANSEKSWEDATKKAVLHAGKTVKNIKSAYVREQSVAIKDNAVSEFRVNVKITFEVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI25</accession>
    <name>A0A5C6ZI25_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Demethylmenaquinone methyltransferase</fullName>
            <ecNumber evidence="4">2.1.1.163</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ubiE</name>
        <name evidence="4" type="synonym">menG</name>
        <name evidence="5" type="ORF">ESY86_10030</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a 2-demethylmenaquinol + S-adenosyl-L-methionine = a menaquinol + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42640"/>
            <dbReference type="Rhea" id="RHEA-COMP:9539"/>
            <dbReference type="Rhea" id="RHEA-COMP:9563"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18151"/>
            <dbReference type="ChEBI" id="CHEBI:55437"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="2.1.1.163"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Quinol/quinone metabolism; menaquinone biosynthesis; menaquinol from 1,4-dihydroxy-2-naphthoate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily. MenG/UbiE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.163" evidence="4"/>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00079">
        <property type="reaction ID" value="UER00169"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043770">
        <property type="term" value="F:demethylmenaquinone methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102094">
        <property type="term" value="F:S-adenosylmethionine:2-demethylmenaquinol methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102955">
        <property type="term" value="F:S-adenosylmethionine:2-demethylmenaquinol-7 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102027">
        <property type="term" value="F:S-adenosylmethionine:2-demethylquinol-8 methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01813">
        <property type="entry name" value="MenG_UbiE_methyltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004033">
        <property type="entry name" value="UbiE/COQ5_MeTrFase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023576">
        <property type="entry name" value="UbiE/COQ5_MeTrFase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01209">
        <property type="entry name" value="Ubie_methyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01934">
        <property type="entry name" value="MenG_MenH_UbiE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51608">
        <property type="entry name" value="SAM_MT_UBIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01183">
        <property type="entry name" value="UBIE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0474">Menaquinone biosynthesis</keyword>
    <keyword evidence="1 4 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4 5" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="4">
        <location>
            <begin position="115"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD89099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="243" mass="26666" checksum="1E3621401B287573" modified="2019-11-13" version="1">MASKVTPYKDSKLNKKQQVTQMFDNISKEYDGLNRVISFGIDVKWRKKVVAIVTNAAPETILDIATGTGDLAINLAKTNAKKIVGLDISDGMLEVGRQKIAKKQLGNKIEMVIGDSENLPFEDSSFDAITVAFGVRNFETLEKGLAEILRVLKPNGVFVILETSVPTKVPFKQGYTFYTKYILPAIGKAFSKDQSAYSYLCESASVFPYGEALNNILRKIGFINVAAKPQTFGVATIYTASKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIC5</accession>
    <name>A0A5C6ZIC5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphoenolpyruvate carboxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_07090</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>oxaloacetate + phosphate = hydrogencarbonate + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:28370"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="4.1.1.31"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008964">
        <property type="term" value="F:phosphoenolpyruvate carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015977">
        <property type="term" value="P:carbon fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021135">
        <property type="entry name" value="PEP_COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033129">
        <property type="entry name" value="PEPCASE_His_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30523">
        <property type="entry name" value="PTHR30523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00311">
        <property type="entry name" value="PEPcase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00150">
        <property type="entry name" value="PEPCARBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00393">
        <property type="entry name" value="PEPCASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="5">
        <location>
            <position position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD89955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="901" mass="103529" checksum="72A0B9A204DBC9CA" modified="2019-11-13" version="1">MNTKENPFQKISDDRIFIINCYTEMLSRIDELEIISLLNNTSQEFTLDENDISTEKIFQSFSIYFQLMTLVEENAATQYRRKMVNQKDFTSIRGSWAEAFKIWKDDSVNEDDMLKTISKTTVIPVLTAHPTEAKRVTVIEIHRELYLLLVQRENTSFSKLEQNVIKEKIINLLERWWRTGEIYLEKPDIRDERANAIHYLGKVFPTVLEKSDQQLKSSWVEFGLNPAKIKNPDLFPKINFGSWVGGDRDGHPFVTPTVTHETLLLHRKTALSLIKDQLLQLIIKLSVSAITNPVPFLLSDAIEKKSKALGEPGLKAVHRNPYEPWRQYVSLLLVQLENTRSEKFADSNSYYKSSTILEEDLKLLREILLQNGLKGLAEDLLFPVERTVKCFGFHLAKLDIRQNSAFHDKAISQILKTIGEKEYDFENWDEDKRVIFLNKLLASNSLITDVTVSYGTEADNVLDCFRVVRQHINQYGSDGIGSFIISMTRNLSDLLVVYLLMRETRLLNTNIRVVPLLETIQDLHNGPEILKKFLQHPVTKERAGKLSHKQEVMLGYSDSNKDGGTIASKWNVYKAEKELTAVGEQNNTEIYFFHGTGGTISRGGGKYHRFLESMPENTVSGIIKITVQGESVAQLFGNPLTATYNLNALSSGVARQTIKKTANAQETVFPLDTMEFLAQKSYEHYKNFIETPGFINFYSKATCIDVLEKSKIGSRPSRRTGARTLNDLRAIPWVFSWNLSRIAITGWYGLGEALKALKTERPEEYENLKKSIQNWSFLKFLIIQVETNLILSNVEIMKHYVALDEDTEERDMFLNKILRDHQNSFVLIEGLFDEPKTERRNGQYDNLKWRNDKLKILHQLHINYLKQWRSIKDENSSEKDKLLTKLLGLINALSSGLKSTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIF5</accession>
    <name>A0A5C6ZIF5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oligosaccharide flippase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07880</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="207"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="241"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="275"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="316"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="349"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="371"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="403"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="422" mass="48706" checksum="231F2F782AA7CED8" modified="2019-11-13" version="1">MIQKLTLYTKKYAIFGMVFSLAKATVYFVPLLLADVLSKSDFGILEYALAGLGMIVNTLINLGVPGAYPYFVLKDSQDHLTPTFRLHAIVLIIPLVINQILFFGFGLDASFYLAFNVSYIIANQVFYSTQLKSHERSTVAVIIDSGIYFFLLFYYIAYQLKIITSSLELINKFILAYAIIYVFFAIQRYLKHKTEVSFQHYKTILKFSIHLLISTFLIYLITSSGRILVELFFDFESVGIYAFYFRLAAIVVMIHQVINIAFFKKIYTFEPKILDKYYFLFFIFIFCLSIIIYFIAPFVVGHFSGYFNETFKEHKAIYFILSAQMVMWIASALNSNIIDRENLASKNNSKFLVLVVVGAGVLYTIKSSITLSMLTYVVYSIIFLACMIQYFSLSRKSIYFQKSALSLAVIYMLTSIYYFINF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIP7</accession>
    <name>A0A5C6ZIP7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type IX secretion system membrane protein PorP/SprF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019861">
        <property type="entry name" value="PorP/SprF_Bacteroidetes"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11751">
        <property type="entry name" value="PorP_SprF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03519">
        <property type="entry name" value="T9SS_PorP_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022773298" evidence="1">
        <location>
            <begin position="19"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="300" mass="33353" checksum="ACAAC1A31CB70E19" modified="2019-11-13" version="1">MKKLYIIIVLLAATQVYGQQDPQYTQYMYNMNVVNPAYAGSKESLSFGLLYRSQWAGIDGAPKTATFFGHTRVGEKVGLGLSVISDEIGPIKETNAYADFSYTLQLGGEHRLAFGIKAGATFHDIGLAGIDLIDQDDQFFQNISTTTPNIGAGIFYYTDNYYLAASVPNILNSVHLDADGNKLGSEERHYFLTGGYVFQLNENTKLKPSFLVKSAFGAPTSYDVNLNALFFEKFELGASYRMDDSFSGIVNFAITPDIRVGYAYDNVTSDIKRFAPASHEFLLLFDLNFSKKVSRSPRYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIT4</accession>
    <name>A0A5C6ZIT4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ACR3 family arsenite efflux transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">arsB</name>
        <name evidence="5" type="ORF">ESY86_04925</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the arsenical resistance-3 (ACR3) (TC 2.A.59) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015103">
        <property type="term" value="F:inorganic anion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004706">
        <property type="entry name" value="Arsenical-R_Acr3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002657">
        <property type="entry name" value="BilAc:Na_symport/Acr3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43057">
        <property type="entry name" value="PTHR43057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01758">
        <property type="entry name" value="SBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005508">
        <property type="entry name" value="Acr3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00832">
        <property type="entry name" value="acr3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="79"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="140"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="218"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="252"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="286"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="315"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR005508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="346" mass="38064" checksum="D63464609E1ACB1D" modified="2019-11-13" version="1">MASKRLSFLDSYLTLWIFVAMAIGVGLGYFIPSFPSIINTFNSGTTNIPIAIGLILMMYPPLAKVNYALLPKVFKNTRILSISLVLNWILGPVLMFVLAITFLRDYPEYMVGLILIGLARCIAMVLVWNDLAEGSSEYGAGLVALNSIFQVFAYSFYAWIFITVLPPYFGFEGAIVDISIQTIAESVAIYLGIPFVMGILSRLILVKLKGEAWYTEKFIPSISPLTLIALLFTIVVMFSLKGELMVEIPMDVLIIAVPLLIYFSLMFIIGFFLTKATGADYDKTTAVAFTAAGNNFELAIAVAIAVFGLNSGQAFAGVIGPLVEVPALIVLVRVSFWLRKKYFKTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIT9</accession>
    <name>A0A5C6ZIT9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_06250</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="HisKA_3" evidence="2">
        <location>
            <begin position="82"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="272" mass="30694" checksum="579FF0885A270527" modified="2019-11-13" version="1">MFFIRFYLFALQEQVIKEEEIALIGYMTIVVLLLSAMVIIFFVTFQKRKNKLLLDQIAQQKAYDVEIARTQSEIQEQTLMYVGRELHDNVGQMLVLAKMQLGMLNAKVDTSLSASFQETSQMVSDSLEEVRALSKSLNSEVLLNTSLVESLQNELDRLKRLVFSSAELIIKGDQTALPNRPHELVLFRILQEFFSNSMKYSEADGIKVILDYQETQLLITASDNGVGFDIASAEKGSGLINMEHRAQLIGAQFDLKSKPNEGVLLVIAYALE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIX0</accession>
    <name>A0A5C6ZIX0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleoside-diphosphate sugar epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10685</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="9"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="220" mass="24554" checksum="904B358607DA3E5A" modified="2019-11-13" version="1">MKKTAIILGATGLTGGILLQKLIDDERYEQIKLFSRSKMEGLPSKVTQYIGDLLELEQFRSDFIADEVFCCIGTTTNKTPDKTLYKQIDYGIPVNAAKLAKDNGISTFLVISAMGADQNSSVFYNKTKGEMERDVLQQQIKKTYILRPALIDGNRDEKRAMESIGLALFKLIDPLLLGPLKKYKMIAAETIAQTMLYLANHPNHSEAIISSTEIKVLSEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ35</accession>
    <name>A0A5C6ZJ35_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD family phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_11930</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="206" mass="23917" checksum="E8C1E4E897B816FB" modified="2019-11-13" version="1">MKTSINTIIFDLGGVLIDWNPEYVYLDVFNGDRKKMEWFFETVCTHDWNENQDAGYPLKQATEDRIAMFPEHEELIRMFYGCWEDMLGGAIEGTVSILKKLIDHPNYKVVALTNWSAETFPIALERFEFLHWFEGILVSGAEQTRKPFPEIYELTLDRFNITAENALFIDDNLRNIKAAEAMGINGIHFESPEQLETELLKNDVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ58</accession>
    <name>A0A5C6ZJ58_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="77" mass="8644" checksum="990CDE0633D3A41C" modified="2019-11-13" version="1">MNSFISLPNLILVSATQLTIVLIITATIFAIFIGAAVIKMFKLKAESKRLLDNSTFKKDVDKSYKDFTDSHLYDSNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJH0</accession>
    <name>A0A5C6ZJH0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Heavy-metal-associated domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_04935</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017969">
        <property type="entry name" value="Heavy-metal-associated_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="SSF55008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01047">
        <property type="entry name" value="HMA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMA" evidence="2">
        <location>
            <begin position="2"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="94" mass="10175" checksum="D1AEB268C0F0A385" modified="2019-11-13" version="1">MKTSIPVQNLNCGGCAHTISSNISSIEHRSNIYVDVETSSVSFEHKDDVNAVLVKARLKSIGYPSIENDNTLSSKAKSFVTCATGKFHSKNSQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJK1</accession>
    <name>A0A5C6ZJK1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_09430</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014717">
        <property type="entry name" value="Transl_elong_EF1B/ribosomal_S6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="147" mass="17080" checksum="C767E610748B614F" modified="2019-11-13" version="1">MAINKTFDQKREFTSLNNEAALLKNAPKQLSLLKLKQRYYDSILNKYQLDGSSIQNNLLSSINDFSNSNDLKVIHFLEPHIINKNDLAIKTYDFTIEGPFDAINRLIYKLEQETKFGEVVSIHYEKKKNFRSGKSYLQVRVLLKSFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJP5</accession>
    <name>A0A5C6ZJP5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_09585</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="113" mass="12576" checksum="DF68887F3F50B94C" modified="2019-11-13" version="1">MKNFILVRQTFSKKSFVFLVIIMHCIMGYSQIPLGQTSNEIETDLPTIIPPSPTVATLMRFEEVPVDHYTGIPDISVPLYSKKVSNNLNFNIGLSYNPVGIRVADRSGWTGTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJY9</accession>
    <name>A0A5C6ZJY9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03925</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="SSF75304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="1">
        <location>
            <begin position="106"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="549" mass="60572" checksum="0154473887F1C3EB" modified="2019-11-13" version="1">MRSLFLLSLFLIFLGCKSSEEEKNQNSESKKDANLSAISNKPFREFKVLDSKYLQSSEIWAAFDEDFRDFTEDTYNALKPLILEQDIPTIQQHIATKKLSYELLTKFYLYRIKTFDRENDLSLNAVIAINPDVINEARQRDKELMGTAERHPIFGMPILLKDNINTRNLPTTAGSVALQENNTETDAFITQRLIENGALILGKTNLSEWAYYFCGNCPSGFSAIGGQTLNPYGRKTLDTGGSSSGSGVAVAANFCVAAVGTETAGSILSPASQNSVVGLKPSIGLLSRSGIVPISSTLDTPGPISKNVIDNAILLDAMSGYDAADFKAYSSNAESRSYFQNLSDASVKSKRFGAFKNLMEDSLYVNAIAVLKSQGAEIIEISEVPVEFPAFLRLLNLDMKKDLPTYFSEYGNQQLNFKTVEDLMAFNEIDSLNTMPYGQNLFKAVAADSASKEEHEAIKQTLKTNGRRFFDIPMQEQNLDAVLSMNNYHAAEAAVAEYPALTVPMGYALDAAPEGLTFISKPKSEKKLLGWGYVYEQASKMRKAPKAYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK17</accession>
    <name>A0A5C6ZK17_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046166">
        <property type="entry name" value="DUF6168"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19665">
        <property type="entry name" value="DUF6168"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="130" mass="15066" checksum="1B61C33616A9F5A4" modified="2019-11-13" version="1">MINAVLKYALYFTLAFAVVYTFQKIVMRDNPEAMRYDYLSVNAFFALTSYVICVLFDVLSGKKILKQQLGYAYLPTLFVKVGLFYLLFKNSIFELANLTLIERLNLLIPLFLFLILEVILMARILAKNNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK43</accession>
    <name>A0A5C6ZK43_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Type IV secretory system conjugative DNA transfer family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_05515</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the VirD4/TraG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003688">
        <property type="entry name" value="TraG/VirD4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02534">
        <property type="entry name" value="T4SS-DNA_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="29"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD90199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="526" mass="59896" checksum="5CB08E381CDDEC40" modified="2019-11-13" version="1">MQIDNLITILSIIGLASTVFYAMFRVSRYAFLLNILLLSILVFYVSEGNELIKLLLYLVCPLLLINTGLYVFLHKTEQAQNGESKYQVNFATTKGNFKLDNIKRGASIIGSAGSGKTESVVYGFLKHFQKENFCGIIHDYKDFELTEMAYPLFKDSNIPFKVISFDKIIHRVNPIAPRYLENEESVNEVSRVLIENLLEQRESGTTGTTKFFNDAAEGLIGGLIWKLKTTYPQFCTLPHLIAIYQYLDTDSLIQFLETNKTSRAMADAFISGKDSDRQTAGVKSTLANALKRISTQRIFMALSADEVPLNINSPENPCVISIVNNPKFETSYSPVIATIIHTITKQMSVRNSEPSFLLMEEAPTIRLLNMHRIPATLRSYNISTIYVMQDKIQNDMMYGDKASKAILSNLSYQFFGKVNDPDTAKYYERFFEIIKDPTKSISRGHNLDFDTRITTGEKEIPKIRADVFFRLKQGEFITYADGKDKKVQFKLSKIQRELPKESNQFSPDDLAANFERVYDEARSIFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKB9</accession>
    <name>A0A5C6ZKB9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="11">RNA polymerase factor sigma-54</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">rpoN</name>
        <name evidence="11" type="ORF">ESY86_02070</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-54 factor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001216">
        <property type="term" value="F:DNA-binding transcription activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000394">
        <property type="entry name" value="RNA_pol_sigma_54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007046">
        <property type="entry name" value="RNA_pol_sigma_54_core-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007634">
        <property type="entry name" value="RNA_pol_sigma_54_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038709">
        <property type="entry name" value="RpoN_core-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32248">
        <property type="entry name" value="PTHR32248"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00309">
        <property type="entry name" value="Sigma54_AID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04963">
        <property type="entry name" value="Sigma54_CBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04552">
        <property type="entry name" value="Sigma54_DBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000774">
        <property type="entry name" value="RpoN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00045">
        <property type="entry name" value="SIGMA54FCT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02395">
        <property type="entry name" value="rpoN_sigma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00718">
        <property type="entry name" value="SIGMA54_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Sigma54_CBD" evidence="10">
        <location>
            <begin position="114"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma54_DBD" evidence="9">
        <location>
            <begin position="328"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD90771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="488" mass="56452" checksum="5E1A5CBD6139CEFD" modified="2019-11-13" version="1">MLKQFLQFKLSQKLSPQQIQLMKLIQLPTQAFEQRLKQEMEDNPALEGGKETSDEFEDNFEEFDNSEDDYNDNETIEAEDINVDEYLSDDDVPDYRTRANNYSADDEEKNVPYAAGTSFTQHLNSQLNTFRLSDEEREIAEFLVGSVDESGYIRRSLSDIMDDLAFTQNVFTSEEKIEKVLNKVHQLDPSGVGARNLQECLSIQLHRKEKNPDVELAIELIDKAFDPFSKKHYQKLIQKFDITEQQLKDAIDEIEHLNPKPGGSYAGNNRIVEHVIPDFAITIVDGELELTLNGRNAPELHVSREYSNMMKGYKEAKDKSKSQKDAVQFIKQKLDAAKWFIEAIKQRQQTLFVTMSSIMHYQKAYFLSGDERKLRPMILKDIADEIEMDVSTVSRVANSKYVDTPYGTKLIKEFFSESMTNDQGEEVSTREIKKILETVVEKENKRKPLTDEKLAKILKEKGYPIARRTIAKYREQLDIPVARLRKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKE4</accession>
    <name>A0A5C6ZKE4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_05065</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="129" mass="15179" checksum="C41B3DA680EA614F" modified="2019-11-13" version="1">MSKWVAISYSLLILAQSVNINFEDISKFKVLLKHANYHAEAYGHSFVDFMAAHYGEARYQHANTHEDHKDLPFKDNQQLLTQFNTSFTLNTIDYVIHQSYFVKIPFNFFYKDTHSLFEKPSVFQPPKLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKE7</accession>
    <name>A0A5C6ZKE7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CoA transferase subunit A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_07565</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 3-oxoacid CoA-transferase subunit A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008410">
        <property type="term" value="F:CoA-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012792">
        <property type="entry name" value="3-oxoacid_CoA-transf_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004165">
        <property type="entry name" value="CoA_trans_fam_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004163">
        <property type="entry name" value="CoA_transf_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13707">
        <property type="entry name" value="PTHR13707"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01144">
        <property type="entry name" value="CoA_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00882">
        <property type="entry name" value="CoA_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02429">
        <property type="entry name" value="pcaI_scoA_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01273">
        <property type="entry name" value="COA_TRANSF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="233" mass="25452" checksum="D8278D174F864BD3" modified="2019-11-13" version="1">MISKKVANVSEALEGIKDNMTLMLGGFGLSGIPENSISKLVELNVKGLTCISNNAGVDNFGLGLLLHKKQIDKMVSSYVGENAEFERQMLSGELEVELIPQGTLAERCRAAQAGFPAIYTPAGFGTEVAEGKETREFDGKMYVLEHAFKADFAFVKAWKGDAAGNLIFKGTARNFNPVMCGAAKITVAEVEELVPVGELDPNQIHIPGIFVQRIFEGKNYEKRIEQRTVRPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKJ0</accession>
    <name>A0A5C6ZKJ0_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">S-adenosylmethionine:tRNA ribosyltransferase-isomerase</fullName>
            <ecNumber evidence="5">2.4.99.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Queuosine biosynthesis protein QueA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 6" type="primary">queA</name>
        <name evidence="6" type="ORF">ESY86_02460</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>7-aminomethyl-7-carbaguanosine(34) in tRNA + S-adenosyl-L-methionine = adenine + epoxyqueuosine(34) in tRNA + H(+) + L-methionine</text>
            <dbReference type="Rhea" id="RHEA:32155"/>
            <dbReference type="Rhea" id="RHEA-COMP:10342"/>
            <dbReference type="Rhea" id="RHEA-COMP:10346"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:82833"/>
            <dbReference type="ChEBI" id="CHEBI:82834"/>
            <dbReference type="EC" id="2.4.99.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">tRNA modification; tRNA-queuosine biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the QueA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.99.17" evidence="5"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00392"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051075">
        <property type="term" value="F:S-adenosylmethionine:tRNA ribosyltransferase-isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00113">
        <property type="entry name" value="QueA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003699">
        <property type="entry name" value="QueA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042118">
        <property type="entry name" value="QueA_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042119">
        <property type="entry name" value="QueA_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036100">
        <property type="entry name" value="QueA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30307">
        <property type="entry name" value="PTHR30307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02547">
        <property type="entry name" value="Queuosine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111337">
        <property type="entry name" value="SSF111337"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00113">
        <property type="entry name" value="queA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 5" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5 6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD90841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="349" mass="40330" checksum="B0C1F150677D5539" modified="2019-11-13" version="1">MKLSHFSFKLPEELLAEHPSEIRDESRLMVLDRKNQTIEHKLFKDVIDYFKEDDVMILNNTKVFPARLFGNKEKTGARIEVFLLRELNEEQRLWDVLVDPARKIRIGNKLYFGEDETLVAEVIDNTTSRGRTLRFLYDGSYTEFRRKLTELGETPLPKYIQRDVEPEDAERYQTIFAKNEGAVAAPTAGLHFSKHLLKRLEIKGVHLPEVTLHVGLGTFNPVEVEDLSKHKMDSEEIFITKPAVDVINRGIREKRRVCAVGTTAMRTVESSVSSNGMLNEFSGWTNKFIFPPYEFSIANCMITNFHTPKSTLLMMVSAFAGHDFMKRAYEEAVKEKYRFYTYGDAMLII</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKK4</accession>
    <name>A0A5C6ZKK4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_07905</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043148">
        <property type="entry name" value="TagF_C"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="436" mass="50587" checksum="C516137BEC1CCE1B" modified="2019-11-13" version="1">MKLLFIENRYKTFLLDAVAKELSQTHDIYWLVQNHSFKPSYGDSYILPYPSAKQLKRVHINYDIDYDQIIQSDRQINFFEKTDTSYLYYYANQIGEQLLKLKPDFVFGEATAFHELLTIELCKKFDIQYLNPTTCRYPTGRFSFYNYASLDPYKGSDESLERATALELIKSITTRTIKPDYMKNAAISKEGSFKDKLKIMKSYYVGERFNTPSPIVKLKLERFRNDSIKRWYTFAKPSIDASKTAILFPMHMQPESNIDVWGRDYRDQFDTVKQIHSNLLNGQILYVKPNPKSKYELSTELMDFIEAHENVTALRHDVSMVEIFEDIDLVTTITGTIAIECILANKPVVTFVRTINNKAANCLYIESFDDLKAVFKLIETKSFPSICEDEKIEFLNMLNRLSFAGVISDPYHNPNCVSQENINSIKNAFESVISIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKM6</accession>
    <name>A0A5C6ZKM6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CBS domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_07210</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd04629">
        <property type="entry name" value="CBS_pair_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044729">
        <property type="entry name" value="CBS_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="27"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="96"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="156" mass="17765" checksum="445AD2576B50BC06" modified="2019-11-13" version="1">MGIKSFQGARKQQSTTEVAALKVSDYMTRELITFRPDQMVEEVIQALIKYKISGGPVVNENNELIGVISEGDCLKDLSESRYYNMPMEQHKVENRMVKNVETIDGDMNVFDAAKVFLDSKIRRFPIVENGKLIGQISQKDILKASLDLKGHNWRKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKX2</accession>
    <name>A0A5C6ZKX2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidoglycan DD-metalloendopeptidase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_07690</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022701106" evidence="2">
        <location>
            <begin position="24"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M23" evidence="3">
        <location>
            <begin position="308"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="84"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="169"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="406" mass="46280" checksum="59E1C57BC2D7C59D" modified="2019-11-13" version="1">MLNNTRLLFIMVCLLASTCIVNAQSPKQQALEAKRLKFKKELAQLNTLLFTDKKKEKSMLSSVEDLNYKVSVRRNLIRVTNDQANLLTREINANQNEISSLRDQLKELKATYAAMVVKSYKSKSEQSKVMFLLSSDNFKQAYKRLQYIKQYANYQKEQGELIKVKTVKLQELNTDLLRQKKDKDQLIVENRTAKAELEIELKQQEKLMASIRKNMSSYASKIKKTQQEIDKIDQEIDRIIKEAIAESNKKAGKSTTSSAFALTPEAKLVAQKFEANKGNLPWPVEKGVVKLGYGTQPSPIDPTVKIKNNGVRIATEKNAKVRAVFKGEVSKIILIKNSNPIVMLRHGNYLTIYKNLSKIYVKQGDIVETNQEIGEVFTDSNGESMLGFGIYKDSNSQNPAYWIYKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLF7</accession>
    <name>A0A5C6ZLF7_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein-L-isoaspartate O-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.77</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">L-isoaspartyl protein carboxyl methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Protein L-isoaspartyl methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Protein-beta-aspartate methyltransferase</fullName>
            <shortName evidence="2">PIMT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pcm</name>
        <name evidence="3" type="ORF">ESY86_00905</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>[protein]-L-isoaspartate + S-adenosyl-L-methionine = [protein]-L-isoaspartate alpha-methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:12705"/>
            <dbReference type="Rhea" id="RHEA-COMP:12143"/>
            <dbReference type="Rhea" id="RHEA-COMP:12144"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90596"/>
            <dbReference type="ChEBI" id="CHEBI:90598"/>
            <dbReference type="EC" id="2.1.1.77"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.77" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004719">
        <property type="term" value="F:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030091">
        <property type="term" value="P:protein repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00090">
        <property type="entry name" value="PIMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000682">
        <property type="entry name" value="PCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11579">
        <property type="entry name" value="PTHR11579"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00080">
        <property type="entry name" value="pimt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01279">
        <property type="entry name" value="PCMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="2">
        <location>
            <position position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD91178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="213" mass="23824" checksum="6FB0A28D4196225C" modified="2019-11-13" version="1">MKDTFKHQGMRQKLVAIVKDKGIKDDKVLTAIGKIPRHLFMDSGFLDHAYQDKAFPIAADQTISQPYTVAFQTELLKIKRSDKILEIGTGSGYQTAVLCELGAEVYSVERQHELYKKTSKFLPKLGYRAKKFVFGDGYIGLENEAPFDGIIVTAGAPFVPKALLGQLKIGGRLVIPVGESVQTMTLIIRKAATDFEQHEFGEFRFVPLLEDRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLI4</accession>
    <name>A0A5C6ZLI4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_02720</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="120" mass="14094" checksum="370A23B08427DA45" modified="2019-11-13" version="1">MLMTFGCQEDDEIEVENTSTNQPNFELQYYSWEHFKQRHKSLANKISSINQDAAFQRGASSSTYGFTIDETEVQVIAQEGFATYTFPVHRETEEMTVVENYVLKQFDDGTYQQYLLTYHY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLJ3</accession>
    <name>A0A5C6ZLJ3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">O-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_05955</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008171">
        <property type="term" value="F:O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002935">
        <property type="entry name" value="SAM_O-MeTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01596">
        <property type="entry name" value="Methyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51682">
        <property type="entry name" value="SAM_OMT_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD90277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="213" mass="24354" checksum="E53D71DC40FA5935" modified="2019-11-13" version="1">MHFLPEKLDHYIVSHSEPEPELLQQLTRETYQKVLQPIMLSGPYQGRVLSMISKLIQPKHILELGTFTGYATLCLAEGLQKDGAIHTIDVNEELFDFQRKYFDVSEYGTQIHQHLGNALDIIPELNMGFDLVFIDADKPNYVKYFHLIIEKLNPGGVILSDNVLWHGKVLAPVAEKDDSTKIVMAYNELLKQDERIETVILPIRDGLTISRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLV9</accession>
    <name>A0A5C6ZLV9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA polymerase sigma factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_03145</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="25"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="3">
        <location>
            <begin position="121"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD90377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="180" mass="21159" checksum="E1BB8C9AA576D6C3" modified="2019-11-13" version="1">MENEEELITRLIATSTKEKAFKELLSLYKERLYWHIRNIVKSHDDADDVLQNTFIKVYKNIHKFKGDSRLFSWMYRIATNESLTNLKQNAKRLKCSSEELQSHAINNLKADVYFEGNAIQLQLQKAIATLPEKQRLVFNMRYFQEVGYREMSEILETSEGALKASYHIATKKIEAYLTKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM88</accession>
    <name>A0A5C6ZM88_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">LacI family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_02850</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="5">
        <location>
            <begin position="5"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="228"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD90912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="353" mass="39924" checksum="F207ECBEF644B18F" modified="2019-11-13" version="1">MRKKVTLKQIAKELDVSISTVSKALRDSIEISEDTRQKVQAFAKLYNYRPNNIALSLKNRKTKTIGIIIPEIVQHFFSKVITGIEMVANRKGYNVIVALSNESFDKEVINMQMLANGSIDGFILSIAKETLQQQDYHHFTETINQGMPIVMFDRVVNEIKCDKVIVDDVKGAKKAVNKLIENGCKNIAIITTKDYVSVGKLRTQGYLEALDDHKINPESSLILKIEDKLLSEDHLDQLENDIEQLFKQNDKIDGIFAVNELYGVTAAKVARRYGYEIPEALQIVSFSDGVLSRHSTPSLSTISQHGQKIGESAAELLIKRLEMEDEEDFNEDEDEIFETVVIETNLIERESTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMJ1</accession>
    <name>A0A5C6ZMJ1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_01505</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="113" mass="12508" checksum="496E0F5975C78CE9" modified="2019-11-13" version="1">MEGILIPISLFLSVFGIFYLYLSTRNKERLALIEKGVDASVFMRGRQRTAPIWKVIILNLALLLMGIGVGVFLATILDHYTILDDAAYPASIFLTAGVGLFVGFKLTKNLDKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZML1</accession>
    <name>A0A5C6ZML1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_01610</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00615">
        <property type="entry name" value="Orn_deC_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000310">
        <property type="entry name" value="Orn/Lys/Arg_deCO2ase_major_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01276">
        <property type="entry name" value="OKR_DC_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="OKR_DC_1" evidence="1">
        <location>
            <begin position="289"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="domain" description="OKR_DC_1" evidence="1">
        <location>
            <begin position="535"/>
            <end position="740"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01276"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="915" mass="104901" checksum="959AADE54D7E6DAD" modified="2019-11-13" version="1">MPEKKQLRSYHYNVAQLRLESWNTLKSQSIKLEYCNRGASEAKDLKHSLRKLLTELEGVESYFAFPGRACLQGLNDMLERQEHTALAHKIADITKNLVSDKYRSNPDFIEDEELGVDASEKGEFQDGVKKNYFEVLFVEDISVQEENKLRNDLRGIRGANEQFNYGIVVQRSFEDALIALHFNYNIQAVVVRYAPPYHSKKITPTLKPFIQNVLKLDLASKPSSELGPILSNLVKKFRPELDTYYVTDTALGNLKDSTLKSFKRIFYRTEDLQELHLTILRGISERYETPFFSALKEYSKKPTGIFHAMPISRGNSIFKSRWINDFGSFYGRNMFLAETSSTTGGLDSLLQPTGSLKKAQEMASDAYGSQNTFFVTNGTSTANKIVVQALVKPGEVILIDRDCHKSHHYGLVLTGAYPVYLDSYPIEEYSMYGAVPLEQIKEKLLRLKEAGRLDLVKMLLLTNCTFDGLVYNVEKVMQEILAIKPDMIFLWDEAWFAFAGFTYTYKQRTGMFVAQKLCEKYRSSAYREEYDAHIKNLKKDEIPSLPNPDKVRIRVYSTQSTHKTLSSFRQGSMIHIWDEDFRRKSENTFMEAYMTHTSTSPNYQMLASLDAGRRQVQFEGYELVEKSIEMAMVLRAKINDHPRLNKYFDVLTVSDFIPKELRKSGLSEYYTPKEGWNRMETAWEQDEFVLDPTKITLHVGRTGVDGDTFKNKYLMDKFNIQINKTSRNTVLFMTNIGTTRGSVTYLTNALLKIADELDEELLSLSAKENKIRQDKIYSLTKDFPPLPDFSYFHHSFQAVPGVPGGDIRDAFFLAYNEENYEYMPLAECLPSMENDRTLVASSFIIPYPPGFPVLVPGQVVSKEIIKFLTALDVSEIHGYRADLGLRIFKDSVLNRQKTVTSMGSMGNNTKKKLIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMR8</accession>
    <name>A0A5C6ZMR8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_01795</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="156" mass="17601" checksum="7BDBE7721B75C868" modified="2019-11-13" version="1">MPDKMKLKQVNSAFLVTTGISVLVFVYLVFLGFDEINNLKDVIKIIASIVFPIPLLLFVRFLVIEHFLPKNTDAYKQKHQKPATILLIATIAIGLGVMQLIEWLTHQTLEDHLIFAHLINSTTISSYVLNFMLYNNLRVNGVLSGVLLALAIHVFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMR9</accession>
    <name>A0A5C6ZMR9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_01245</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ArsC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006660">
        <property type="entry name" value="Arsenate_reductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03960">
        <property type="entry name" value="ArsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51353">
        <property type="entry name" value="ARSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="136" mass="15514" checksum="795FC0FEA77FEC6D" modified="2019-11-13" version="1">MASISTHKNMIKIYYSSESSIGKQTYGYVNASFKELLGIDVTKDKVTGTQWKDIAEHLDIPISGLIDKEHPLFTENYDKDANLDQDGWIKVLNNHPEVLNYPIVIMGNKYMQIRNPSDIAKHLDPNSQGIDEKKYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMS6</accession>
    <name>A0A5C6ZMS6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_01845</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023004172" evidence="1">
        <location>
            <begin position="26"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="120" mass="13619" checksum="15335708396CE519" modified="2019-11-13" version="1">MKKQLLLLSFAVCLFLGSQSTFAQAASNVQNQAYSSEATPKMRAMRVIETFSRRTDVSAEQKDAIITLFNDNQRKYSAIATLEDPKQKVEKEAKMQVYIDKQLKGILTEDQFGLYTKSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMT5</accession>
    <name>A0A5C6ZMT5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chemotaxis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_00740</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024478">
        <property type="entry name" value="HlyB_4HB_MCP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12729">
        <property type="entry name" value="4HB_MCP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="4HB_MCP_1" evidence="2">
        <location>
            <begin position="8"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD91149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="202" mass="23912" checksum="FA06EC2E88BA57C2" modified="2019-11-13" version="1">MNFYNKVKWVLGILMVFILILSTNLIDRNNFARVKESVVTLYEDRLVANDLIFEMSRLIHEKDISLATNDSLYFSKRNRQVNEEINDNLAQFELTRLTRKEEQVFDELKSNIETLMTVETNLERLWPNQNTKASNRISKIRINLHELSKIQLNEGKRQLSISKKAMNTVELFTQIEIYLLIFLAIVIQIIVMYNPKRKEETE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN42</accession>
    <name>A0A5C6ZN42_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Universal stress protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_04960</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal stress protein A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="2">
        <location>
            <begin position="2"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="284" mass="32301" checksum="C9E010F20E42B8F4" modified="2019-11-13" version="1">MKRKILLPTDFSDNSSQAINYATELYKDVPCVFYLLNVFYIKSKDIESIINMDKGSPMYEASKANSESGLNKLLDHLDPKENGNPNHSFETVTVFNNIVEAIKTVVEEKDIELIVMGNRGETNSRSIVYGNTALDVMEKIRNCPVIVVPQSAKMGLPKEIVFPTSYKTHFKNRELSYLIDIAKKCDASIKVLHISNEDHLTEKQLKSKKLLEDIFKDVNHSFHYLSNMSVPKAINCFVESRESDMVAFINKKHTFFSSILSQPLVKGIAYDSKVPMLVMHDLRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN44</accession>
    <name>A0A5C6ZN44_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ZIP family metal transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="205"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="224" mass="24858" checksum="3E3A321EEA7D8FAC" modified="2019-11-13" version="1">MISYLLPILAVVFGFLIAIATKNTQKTATKLLLSFSGAFLLALTLFELLPEVYQHLDAKTTGLFIMCGILLQIILEFFSKGAEHGHVHIHKEETDFPWSLFVSLCLHSFLEGFPIHEHNDMVYGVLVHKIPIAVLITTFLLQSSFSKTKIASFLIVFMLMTPLGTLASNNLTIDTAYLSMINALVIGIFLHISTTILFESGEGHKFNLSKLVAIVLGIFIAYLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNA7</accession>
    <name>A0A5C6ZNA7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_00480</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045538">
        <property type="entry name" value="CIS_TMP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19268">
        <property type="entry name" value="CIS_TMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="390" mass="45692" checksum="36BCA4C9557E5928" modified="2019-11-13" version="1">MKQWKNEFLHKALAQIRLFLRQQPYTGLPQNSKNYYDDSIEKEIVFDSIGLIIDFLKTGNFKNSQDGKKLDQILKEIEWNSQNRAEVLKVICTDVQSILRFVFSMPVGIRENILGEKRLIFYQVHKKSDRYALPNPSKKLFVSELNDFLEVIYRAESLPNGIQQNFSQILKTNFEVTEKEYQKWLDTQTNPVKTKFKKLEALKNNMSIKADDVQIESDTNEESYYISNAGLIILHPFLQKLFEKLGYLTDDKNSFKSKNLQNRAVLLSQYLVTFEEQIFENDLVFNKVLCGVKMTDAINTKITFSIEEKEVCRDLLIATISHWKILKNTSPESLQSSFLQRKAKLKKDENNWGLFVEKQGLDVLLNHLPWGINTVRTPWMNRHLTCNWSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZND9</accession>
    <name>A0A5C6ZND9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_02420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="123" mass="14002" checksum="5EE2669D58C6320D" modified="2019-11-13" version="1">MNDICVSTAITIILISHLAAIAIGYKMQKTTLIISYLNTVIVIGIFVFWAITSPNLKQHNFELRELLVICLEACILIFAFYAIIGFHNKTYVKVINFIGFGNHLLATTGMLYYMLAFKFDRLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNJ2</accession>
    <name>A0A5C6ZNJ2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Rod shape-determining protein MreD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">mreD</name>
        <name evidence="9" type="ORF">ESY86_05800</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MreD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007227">
        <property type="entry name" value="Cell_shape_determining_MreD"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03426">
        <property type="entry name" value="shape_MreD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0133">Cell shape</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="51"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="114"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="145"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD90250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="168" mass="19392" checksum="29FFE80DB2977F20" modified="2019-11-13" version="1">MNSLNTNIILRFIVLILAQVLVFNHINFMGQINPYPYILFVLLYPVKNNRTLFLLLSFIFGLFVDLFSNSGGVHAAACVTIAYIRPGLLKFCFGMLYEHQSIKFNQTDLTNRMLYFSVLTVCHHLILFSLEIFNVSNVIMILQKTLFSSIFTILLCFLFTVLFSSKQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZP21</accession>
    <name>A0A5C6ZP21_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">EamA family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_01110</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="221"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="254"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="282"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="143"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD91217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="300" mass="32981" checksum="7E86DAB05387ABE8" modified="2019-11-13" version="1">MYLLLSIAASTFIFIIFKLLGKYNINTLHAIVVNYFVACLLGIVLYDGKIVLAEIVASYWFYGALVLGFLFISIFNVMALTAQRNGLSVASVASKMSVILPVVFGIYVYDEGVGFQKLLGIFIALIAVYLTSLRAKSSVSLTKGIWLPIILFFGSGTIDTMVKYLETTYVPDNGIPIFSATIFLFAFIIGIGLLAFNRFIKPRLMPTSEITSGEKKQKSDWRVLLGGSALGIVNYMSIYYLLKALDHETLESSTLFTVNNVAIVMISTLLGLLVFKEKISKINWLGISLAIVSIVLVTLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZP81</accession>
    <name>A0A5C6ZP81_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Polyphosphate kinase</fullName>
            <ecNumber evidence="6 7">2.7.4.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">ATP-polyphosphate phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Polyphosphoric acid kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">ppk1</name>
        <name evidence="6" type="synonym">ppk</name>
        <name evidence="9" type="ORF">ESY86_02375</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>[phosphate](n) + ATP = [phosphate](n+1) + ADP</text>
            <dbReference type="Rhea" id="RHEA:19573"/>
            <dbReference type="Rhea" id="RHEA-COMP:9859"/>
            <dbReference type="Rhea" id="RHEA-COMP:14280"/>
            <dbReference type="ChEBI" id="CHEBI:16838"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="PTM">
        <text evidence="6 7">An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the polyphosphate kinase 1 (PPK1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.1" evidence="6 7"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009358">
        <property type="term" value="C:polyphosphate kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008976">
        <property type="term" value="F:polyphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006799">
        <property type="term" value="P:polyphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1840.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00347">
        <property type="entry name" value="Polyphosphate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003414">
        <property type="entry name" value="PP_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041108">
        <property type="entry name" value="PP_kinase_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024953">
        <property type="entry name" value="PP_kinase_middle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036830">
        <property type="entry name" value="PP_kinase_middle_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025200">
        <property type="entry name" value="PPK_C_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025198">
        <property type="entry name" value="PPK_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036832">
        <property type="entry name" value="PPK_N_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30218">
        <property type="entry name" value="PTHR30218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02503">
        <property type="entry name" value="PP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13090">
        <property type="entry name" value="PP_kinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17941">
        <property type="entry name" value="PP_kinase_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13089">
        <property type="entry name" value="PP_kinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015589">
        <property type="entry name" value="PP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140356">
        <property type="entry name" value="SSF140356"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03705">
        <property type="entry name" value="poly_P_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 6 7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PLD phosphodiesterase" evidence="8">
        <location>
            <begin position="578"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphohistidine intermediate" evidence="6">
        <location>
            <position position="426"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="366"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="396"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="459"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="555"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="583"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD90826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="674" mass="78188" checksum="8E46CD89F4FD4465" modified="2019-11-13" version="1">MKLYNSKFYHRDLSWLRFNHRVLQEASDKLNPLYERIKFLAIFSSNLDEFFRVRVSDIRQIRQVEKPLRKKLITKPNKVLQEIKKQVDIQQTAFGKVFKEEIIPDLEKENIFLIDYHEFSDSQKAIANDYFEKTLKDLLALETTYHKNPDTIFVENEASYLCTMSGETLHLVKIPDSEPRFFSFPSEGGKHYISFIDDILKYNLAKIHPDDAVRYYALKISRDAELYIEDEFSGDLMKKIKASLPKRDKGQPTRVLIDERMPKSFQDILMKALDVYNADLILGGRHHNFKDFFSFPNPTENEKLHFEPLPPLPHPVLSKSKNIFDTIEEKDQLLNYPYEAFDPVITLLETAASDPTVTAIKMTLYRLANESRLNTAIAKAAKNGKEVILFIEVKARFDEQNNIKWGAIFKENGAKVIYSYADIKVHSKILYIERLVNEEIKRYAYISTGNFNSKTAELYADYGLMTAHKKITKDLNKVFMVLQGITLIPKTKCLLVSPFSTRHTLEQLVDQEMENARDGKEAYIILKMNSFQDHALIKKLYDANNVGVKIKLIVRGMCSLVAGIENQSEHIEVISILDRFLEHGRVYIFGNDGDEIMYIGSADWMTRNLKHRIEVLTPILDADIHKMLRELVDIQLKDNVKARIIDAEQTNTYVKNSKPKVRAQYATYAYFEGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZP96</accession>
    <name>A0A5C6ZP96_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_03695</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022722805" evidence="2">
        <location>
            <begin position="21"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="138"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="251" mass="28671" checksum="B6832653EE4976A7" modified="2019-11-13" version="1">MKQAYLIIFLFTFIFTTAHSQQSNTKNVRYNLGEVSKNVTSGIESYNLEDLKYHARICKEAIEVVEKLVEAEQCYNTLDLSNSIAIYLETALLAEELVTARTYLNKTEELILKAFYEYDICKSELSNAKSSKYGENALNTLQQKQADLKARQAGLEQQAKDIELQLAEQEKRESLLKKQQFIASNERAITRNINTYNDVLKSCDCQDTMSYASESVSVISAKNFQDIRMHYLDTIIGISENYTSKLKACKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPG6</accession>
    <name>A0A5C6ZPG6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ATP-binding cassette domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_01665</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="6"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD91317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="231" mass="26308" checksum="78E1ECC57263591A" modified="2019-11-13" version="1">MSEPILKLKDVAIYQGDSMVLSDVNFEMHKGDFVYLIGKTGSGKSSFMKTLYGDLELTEGEGHVVDYDLRNLKEKDIPFLRRKLGIVFQDFKLLPDRTINGNLEFVLKATGWKEKDKIKERIEKVLDKVAMKTKGFKFPHELSGGEQQRIAIARALLNDPELILADEPTGNLDPQTSIEVMEVLRDINKNGNTILMATHDYALLLKYPSKTLKCDDNKVFEVVQRRDSMVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZQ65</accession>
    <name>A0A5C6ZQ65_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ammonium transporter</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">amt</name>
        <name evidence="8" type="ORF">ESY86_02310</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ammonia transporter channel (TC 1.A.11.2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008519">
        <property type="term" value="F:ammonium transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029020">
        <property type="entry name" value="Ammonium/urea_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001905">
        <property type="entry name" value="Ammonium_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024041">
        <property type="entry name" value="NH4_transpt_AmtB-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00909">
        <property type="entry name" value="Ammonium_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00836">
        <property type="entry name" value="amt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0924">Ammonia transport</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="42"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="104"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="128"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="207"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="236"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="270"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="294"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="324"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="350"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="Ammonium_transp" evidence="7">
        <location>
            <begin position="9"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD90813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="410" mass="43826" checksum="77D1F478358B806D" modified="2019-11-13" version="1">MELLTINNVWMMMCTALVFFMHLGFALLEIGLTRQKNTLNILFKNVFIITIGLLLYCLVGFNLMYPGEFNGFFGFAGFGLDSPLTADGALDLTYNEGYTYWTDFLFQGMFAATAATIVSGAVAERMKILPFMIFTIIYVGLIYPIAGSWKWGGGFLQTLETPFHDFAGSTLVHSVGGWAAVVAVCLLGARIGKYKDGKPQAIPGHNIPLATAGVLILWLGWFGFNGGSVLSAEPGMTSLVLVNTSLAAAAGGVVCMLVSTVRYKNLDLTMFLNGILGGLVAITAGADQMAPTDAIIIGAIGGAIIVFAVSLIDRLKLDDPVGAIAVHLICGIWGTLAVGLFGNLAGGNQFLSQLIGVGSYALFCIVSSFIIIFFLKKTIGIRVSEAEELDGLDAHEHGMEAYPNFRLNEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZR27</accession>
    <name>A0A5C6ZR27_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="165" mass="19590" checksum="943E113CE09E73DB" modified="2019-11-13" version="1">MLEQFKTRWEIKENWQLLFPLLGVLGLGYSAYRLAAVLLKDLPPVLVLLTAGLIFWLLLKLVLFIFKKLKHKWVVDYRWEMIRIFIVFAITGSSSLFVGRPIIALLGITKENLNPIVYWVLFIIIGLIFYQMLLVSFGWLFGQFKFFWEFEKKMLRRFGFGKFLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAP5</accession>
    <name>A0A5C6ZAP5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Magnesium transporter MgtE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">mgtE</name>
        <name evidence="9" type="ORF">ESY86_18430</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Acts as a magnesium transporter.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the SLC41A transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000031">
        <property type="protein sequence ID" value="TXD87035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015095">
        <property type="term" value="F:magnesium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.60.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006668">
        <property type="entry name" value="Mg_transptr_MgtE_intracell_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038076">
        <property type="entry name" value="MgtE_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006669">
        <property type="entry name" value="MgtE_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006667">
        <property type="entry name" value="SLC41_membr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036739">
        <property type="entry name" value="SLC41_membr_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43773">
        <property type="entry name" value="PTHR43773"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01769">
        <property type="entry name" value="MgtE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03448">
        <property type="entry name" value="MgtE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00924">
        <property type="entry name" value="MgtE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161093">
        <property type="entry name" value="SSF161093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00400">
        <property type="entry name" value="mgtE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0129">CBS domain</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="293"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="320"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="367"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="394"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="432"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="8">
        <location>
            <begin position="147"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="8">
        <location>
            <begin position="211"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD87035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="457" mass="50782" checksum="A9239DB1E3413C9E" modified="2019-11-13" version="1">MIEEKENIQFELTDELVAQVEHLVETRNDEELKSLLEDFHHADIAEILDELDLDDSVYVIKLLDSETTADILIEMDEDNREKVLRNLSAKEIAEEIEELDTDDAADIIAELPEERQAEVISNIEDKEHRKEITELLAYDEDTAGGLMAKELVKVYETWTVAGCLRRIRVQAKDVTRVHSIYVVDKKNKLIGRLSLKDLIVAKAEHKIADIYIKTVDYVHVDDDAEDVARIMQKYDLEAIPVVDSNQKLLGRITIDDIVDVIREEADRDYQMAAGISQGVEADDSILKLTRARLPWLLIGMFGGLGAASIIEYFNGEMGDFIVLLSFVPLIQATAGNVGVQSSAIIVQGLANDSLDGKIFKRLLKEALLGLVNGLAIACIALVITHFLFGTPYIVSITVGIALISVIVMAAMIGTFIPIFLDKRGIDPAVATGPFITTSNDVFGILIYFVIAKLILQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZB74</accession>
    <name>A0A5C6ZB74_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_18530</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000032">
        <property type="protein sequence ID" value="TXD86991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="589" mass="67732" checksum="273434C6FF6273EB" modified="2019-11-13" version="1">MNQLWFEMKDLKKRKLDKSVWIPLRSDKSIRNNIEFGEVGYIDDFIGHGTLMLPVSKKPMTKDLDWMDVGINHAHSFNYLYGEYSQSEMFENSDFQGIHLVLNQNFDNNYDNNEWHLHQDLVINLGLKREKDIWVCPRRGYVEVAKLERNKEGSPILIQIKNQFLKDYLCARNCGLYITSYFCRDEIFSNREILSWRGDSKSTKEGKDVWECRVLEIHEGGFSFGEKIAISHASRTDVDEAEDIPDMTSFPTDSNIKSEFHEKSFKGKKLYRIIAEFWKYEWINPAKSSPVVLGEEQQIDMFYIVDAEGNKESGEELKKGGKWLWFSPELVSSLILKRGGFLSWYSKNTGSISCAPSFGVHFGMNDLGLITVYAKDVGNLPIWQQQIWVGHNISPEGGISKELYDSQVKAVPASTLAPEDFIEKVINQINEASKQNLNIDFFRGHHSINEIINSISRFRAVDDKGLFSLAKDIARIIVDDIDIESLQKIATPPKKTKWGSLKTVENLLAIKIPKEDARKILSSFVGVYELRHGDAHLPSSEIENSFKLILIDRNKPSIIQGYQMIFACVDNLHLILSIIRKWNVIEQEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZB92</accession>
    <name>A0A5C6ZB92_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Nucleotidyl transferase AbiEii/AbiGii toxin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000036">
        <property type="protein sequence ID" value="TXD86854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014942">
        <property type="entry name" value="AbiEii"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08843">
        <property type="entry name" value="AbiEii"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="327" mass="38153" checksum="296B675D0B97D5D9" modified="2019-11-13" version="1">MKLHENKELFQDAITATSQQKGIPEIYIEKDYWVTLALHSIFNNEIGKETVFKGGTALSKCNQLIDRFSEDIDLVVLRKDGETNNQLKSKLKKISKCVSKVIPEIEIDGITHKMGMIRKTAHSYEKSFDGDFEHVRDTIILESTWLGHFEQYTKGTVSSYIYEMMLKAYQQDIIVQYGMHPFEVLVLSTERTLCEKLMSLVRFSQTEQPITDLRNKIRHTYDIHMMLKDDELNSFFNSKAFDVMLLKVANEDVISFKNNNSWLSNHPINTILFSETENTWNQIKDTYETSFKELVFGEFPSENEIMNTLKLVAERLKTIEWNIETKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBC8</accession>
    <name>A0A5C6ZBC8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF3875 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_19910</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000051">
        <property type="protein sequence ID" value="TXD86574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043964">
        <property type="entry name" value="P-loop_TraG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024451">
        <property type="entry name" value="TraG_N_Bacteroidetes"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12991">
        <property type="entry name" value="DUF3875"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19044">
        <property type="entry name" value="P-loop_TraG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3875" evidence="1">
        <location>
            <begin position="4"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="domain" description="P-loop_TraG" evidence="2">
        <location>
            <begin position="396"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="478" mass="55088" checksum="EE1B5693FE1FDDED" modified="2019-11-13" version="1" fragment="single">MNKINLSAYQPIADIQDNIVFANNGNVVLCYEGNLPEIYSLSEKDFEDMHGSWFQALKSLPVGTVVHKQDIYLKKSYSSEQLPNKTFLEKATHEHFKGRGHIEHKCYLFFILTKNKALNNPKYVNPFRKISKGIVQELDDNIKSFANSVSDSVSFINNSRKMAFLPLNANEIQQLTNSYFNGFNEGFDTDILLDKKSVNIGENHFDALAINSELCFGESVQSSKTNEKFTSDDFVFHQGFVDGLGLTLNENHIINQILYLDDKQKWRKLLDKKIEELNKSSNFGSQNKVVLGKIQHILDQINADDNARIIRGHLNIVYWAKEAKELDKITSKIKTEFKELDIIPYYPRGEERKNYILNSYCCFSSNFSNNDLYVTDLKHALCLFINNTNYKSDNTGIIFNDREHNIPVLKDVWDEKKKRIKARNFAIFAPTGEGKSFLANNILRQYFESGVRLVIIDLGGSYTKFAKLYPEKYTVLRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBH0</accession>
    <name>A0A5C6ZBH0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Universal stress protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_18635</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal stress protein A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000033">
        <property type="protein sequence ID" value="TXD86947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="2">
        <location>
            <begin position="3"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="276" mass="31284" checksum="B5F69C01727C4375" modified="2019-11-13" version="1">MKNNILLPTDFSENAWSATEYATKLFANEDCNFYFLHASQPPSGRISVSSTKLARVMAENDLKSLSEFKTKAEKTFPNSKHKFNILLSQNDLFDAIEVTLSQHGIDLVIMGTKGASRSEDLFFGSNTVNVIKRIKSSAVLMIPDGFNFVKPKQIAFPTDFNRSYGKEIEYVKQMCGLYKAKISVVHISDNLELSEAQHEQQKVLESVLEHIPHSFNSVLDSGKKEHAIKDFIEEHDIDILAMIYYTHSFLEYVTKEPVIKRIGFQPTIPFLVIPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBN2</accession>
    <name>A0A5C6ZBN2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD(P)H-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000040">
        <property type="protein sequence ID" value="TXD86739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN_red" evidence="1">
        <location>
            <begin position="7"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="177" mass="19727" checksum="122A56CFECFD6945" modified="2019-11-13" version="1">MTEKKNIFIIIGSASRNSANEKLVENFVDLTKDVFNLTVFKDLKTLPHFDPELSADNAPAEVTEFRKNIENADGILICTPEYIFSIPSGLKNGIEWCVSTTVLSDKPIGLITASASGQKGHEELQLIMKTVLTKFTDETTLLIQGIKGKINEQGQITDDKTKENFMKFIDAFKKIIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBV7</accession>
    <name>A0A5C6ZBV7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_17665</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000027">
        <property type="protein sequence ID" value="TXD87262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="6"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="131" mass="14963" checksum="4D72A881391511AB" modified="2019-11-13" version="1">MNKINLTCIIDDDPIFIFAAKRILKVSNFCNNFTIFNDGEEAINKLKPIIESGDNVPDIILLDLNMPIMDGWQFLDEFIKMKTTKQIALYIVSSSIDPVDLEKAKTYETVTDFIIKPLSKAKLEKITADFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCA4</accession>
    <name>A0A5C6ZCA4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA small subunit methyltransferase A</fullName>
            <ecNumber evidence="6">2.1.1.182</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">16S rRNA dimethyladenosine transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">16S rRNA dimethylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">rsmA</name>
        <name evidence="6" type="synonym">ksgA</name>
        <name evidence="9" type="ORF">ESY86_18435</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>adenosine(1518)/adenosine(1519) in 16S rRNA + 4 S-adenosyl-L-methionine = 4 H(+) + N(6)-dimethyladenosine(1518)/N(6)-dimethyladenosine(1519) in 16S rRNA + 4 S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:19609"/>
            <dbReference type="Rhea" id="RHEA-COMP:10232"/>
            <dbReference type="Rhea" id="RHEA-COMP:10233"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74493"/>
            <dbReference type="EC" id="2.1.1.182"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.182" evidence="6"/>
    <dbReference type="EMBL" id="VORO01000031">
        <property type="protein sequence ID" value="TXD87036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052908">
        <property type="term" value="F:16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00607">
        <property type="entry name" value="16SrRNA_methyltr_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001737">
        <property type="entry name" value="KsgA/Erm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023165">
        <property type="entry name" value="rRNA_Ade_diMease-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020598">
        <property type="entry name" value="rRNA_Ade_methylase_Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011530">
        <property type="entry name" value="rRNA_adenine_dimethylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727">
        <property type="entry name" value="PTHR11727"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00398">
        <property type="entry name" value="RrnaAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00650">
        <property type="entry name" value="rADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00755">
        <property type="entry name" value="ksgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51689">
        <property type="entry name" value="SAM_RNA_A_N6_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="4 6 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="rADc" evidence="8">
        <location>
            <begin position="23"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD87036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="263" mass="30059" checksum="F87658D7D0818265" modified="2019-11-13" version="1">MTNQNQVRAKKHLGQHFLKDESVAEKIADSLSYKGYDQILEIGPGMGVLTKYLLNKDTTTHVIEIDTESVDYLKANYLNLSNRIIQQDFLKYDLNLVFNGEPFAIIGNFPYNISSQILFKTLEMRAQIPEFSGMFQKEVALRICSSEGSKVYGILSVLTQAFYDAEYLFTVPPHVFNPPPKVDSGVLLLKRKANFELPCDEALFFRVVKTAFQQRRKTLRNSLKTFNLSDNLKANTIFDKRPEQLSVPLFLELTSLIQEDSNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCI9</accession>
    <name>A0A5C6ZCI9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sodium:solute symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_17270</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000026">
        <property type="protein sequence ID" value="TXD87313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="117"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="148"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="181"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="231"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="271"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="455"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="480"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="509"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="533"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="566"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD87313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="591" mass="65865" checksum="6AC362A7403BF079" modified="2019-11-13" version="1">MQALDWIILITTLVAIVAYGTYQTRGSKNVQDYLKGGNTTPWWTIGLSVMATQASAITFLSTPGQAFNDGMGFVQFYFGLPIAMVVICIVFIPLYHRLKVYTAYEFLENRFDLKTRTLTAILFLIQRGLAAGITIFAPAIILSAVLGWNILVLNIVIGVLVIIYTVSGGTKAVNVTQKHQMVIIFTGMIIAFFIILNQLPDDITFTKALDIAGASGKMEVLDFSFDLNNRYTVWSGIIGGTFLMLSYFGTDQSQVQRYLSGKSVKEMQLGLIFNGLLKVPMQFFILLIGVMVFVFYQFNAAPVNFNPTATDVVLTSEYAEEYEDLQQKQQAIFEQKQGIINDFVSENNSENFKSIALANAQQDQIRVQAKTLIDKAGKSKSIKVESNDKDYVFIHFILNNLPKGLIGLLLAVILSAAMSSTSSELNALASTTTMDLYKRNVSEKTETQMLNSSKWFTLLWGIMAIGVACVANLAENLIQLVNIIGSIFYGNVLGIFLLAFFFKFVKGNAVFTAAIITQFLVIALFLLNEYDVIKLPFLWLNFVGCFIVIIIAMLIDFKKLGKLDKWILLGLSSILFYFGYLIYENSQILIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCL4</accession>
    <name>A0A5C6ZCL4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">T9SS type A sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_20280</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000063">
        <property type="protein sequence ID" value="TXD86405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013517">
        <property type="entry name" value="FG-GAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028994">
        <property type="entry name" value="Integrin_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13517">
        <property type="entry name" value="FG-GAP_3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69318">
        <property type="entry name" value="SSF69318"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022807062" evidence="2">
        <location>
            <begin position="20"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="domain" description="Por_Secre_tail" evidence="3">
        <location>
            <begin position="784"/>
            <end position="850"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD86405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="852" mass="96598" checksum="2D8ADF0ED360CF36" modified="2019-11-13" version="1">MKLKTLSLIAFIIFSNAFAQLDLDNLNIINDNYKIYDYVLSDIDNNGFKDLVSSGFICDRVGSSQTIIVWQANDNYGNFGIRNILYTGQAGEIDSKDIDNDGDNDIVFASGNVINVIKNNNNGTFSNVESFPLSTNGISDFYLMDMDNDSYVDIVYRDYWGVIKIKWNLTNGQFGNSNNTYGSSDLGYKIIDINNDDLPDFVFNNNTYFRFKLNQGNRIFNIGESFYISYGNAFDLGDFNNDNQKDLIVSSGGTLKIYYNQAIASPNNMFDSNNNIEIFSDGNINFTGIELADFNNDTFLDIAFNSSGSSASGNNLILENNNNIDFLNQYQFEGPSNTPEASDLNNDGLLDLFVFNPSFFYGNSGHYSTFSINNGNFDFQFQNYSNSTLKSTHTIADINNDNLKDIISFSYEDGYGYEIQYLINQGQDKFSRRAIALETPNISIRTNVKPLIFDMDNDNLKDIILIGNDNDSVDKILWIKNLGNDSFASVFSLSETGFYIIDPDKTKMFYGDFDNDNDNDLFLSYQFYENVNGVFQNATSFNTDGSHSAQHIFNSDNNSTINIIATKITIVGIDKYMSVKWFKYDSQGNLTSTNNVGYYDIGDYFSSASSNPNINNFTFIDFDNDGDKDIIYSLSCESLLCAPEFYILKNNGNDSFDNPDTLIPRTSFIDEGRSTDIEIVDIDNDNDVDIIETSYKENTSYDTTRSKIHFNDNGSFNRTETLFSYAVQNKCEELKIEISIEDMDNDGVLDLLKCNPYEYLIAGLDIYDSSLSIEENEFESQFNIYPNPTSDYIHIESKFNIALLTVYNQKGQLILENKNENKINISKLNEGLYFLKIIDKNGYIQTKKIIKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCX4</accession>
    <name>A0A5C6ZCX4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000026">
        <property type="protein sequence ID" value="TXD87336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="95" mass="10970" checksum="25296BE7FF8616F9" modified="2019-11-13" version="1">MRKRVKTFEVWTFKANHSGTYKLNLKNLEEFLEANPFLKSKKPFSNRKTETKKLKILIKQSISTKDRLISIIGLALGINGLFWGLILGINPSMFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD77</accession>
    <name>A0A5C6ZD77_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_18005</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000029">
        <property type="protein sequence ID" value="TXD87122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="129" mass="15031" checksum="82DD9F8E5F44EF81" modified="2019-11-13" version="1">MPYQDEFVLFWDQVRESIHDRRFAKLTMAKTIGKPNLKNIFVRPIYSEDGFKVLVKLRYASKETEDEEKELTLEDAFEFLKSHLKAPFSTVLLFTTTKDVTFKINKKGAGTITENVPTFRDVTQAKTDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDK7</accession>
    <name>A0A5C6ZDK7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Amidinotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_14990</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="304" mass="34938" checksum="C1CBF1D21425049D" modified="2019-11-13" version="1">MIKLNIKNETSRLRAVVLGTANSNGPTPKIEEAYDPKSLEHIKAGTYPVEADMVKEMEAVAKVFEKYDVTVYRPELIADCNQIFSRDIAFVIDDVFVKANILPNREEELDAIQYVIDQVDPEKVIRPPKEVHIEGGDVILWNDYIFIGTYTAEDYPDFIVARTNTQGVEFIKKTFPHKKVKSFDLRKSQTNAMDNALHLDCCFQPIGKNKAILHKEGFLNVEEFEWLLNVFGKENCFIIDKEEMYHMNSNVFSISESVIISERGFTRLNAWLRQQGFTVEEVPYAEISKQEGLLRCSTMPLIRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDM2</accession>
    <name>A0A5C6ZDM2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19405</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000040">
        <property type="protein sequence ID" value="TXD86740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="227" mass="26727" checksum="B30A154762BF8240" modified="2019-11-13" version="1">MKLFNFIQKKQSTDKTPNQIIKNLIDYLPADYNDQRQLKDSIEFLNQNELGLALDSLIELTEETGHYFSDKYWLDLADAADKMELIKERDFCHQQIRKTETELKFKVSFGSTVEKIDDNHFQDYTSEKIKDNWAKERREKDNVEQLMNNDGLHFKSHGRNGFFYFVDKGKLAEIEYELGVNGLIIWFNSTDNWAKPSKLPLTTDEKLTIKTEIEKWAAKTRNAIELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDZ1</accession>
    <name>A0A5C6ZDZ1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SDR family oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000026">
        <property type="protein sequence ID" value="TXD87318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021295">
        <property type="entry name" value="DUF2867"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11066">
        <property type="entry name" value="DUF2867"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="7"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="474" mass="54331" checksum="7728D902B0415CA3" modified="2019-11-13" version="1">MKILVTGGTGYIGKRLIPLLINDDHDVVCAVRDKLRADKSYLEEEHIEIIEADFLKPETLSNIPKDIDIAYYLIHSMSNSSKDFESLEEKCAINFKAYIEKTDVKQVIYLSGITNEKKLSKHLRSRKNVEHILESDQYGLTIFKAGIIVGSGSSSFEIIRDLVEKLPVMIAPKWLNTKSQPLSVRDVLFFLSRAAGDERLYNHSYDVFGPEILTYKEMLLRFAEVRGLKRYILTVPVMTPKLSSYWLYFVTSTSYKLASSLVDSMGVQIIGNPSNINEMLNVEPLSYKTAVKLAFEKIEQNSIVSSWKDSMVSSGRLRNSFHKYVNVPVYGCFKDYKERSVIDTEKTLDKIWSIGGTTGWYYGTILWKIRGYMDKMFGGIGLRRGRTHVSQLDAGDALDFWRVIFADRDMKKLLLYAEMRLPGEAWLEFKIEDGMLKQTATFRPRGLAGRLYWYAVFPFHGFIFNGMADKLVEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE63</accession>
    <name>A0A5C6ZE63_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA polymerase sigma-70 factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_18580</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000032">
        <property type="protein sequence ID" value="TXD86997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014327">
        <property type="entry name" value="RNA_pol_sigma70_bacteroid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02985">
        <property type="entry name" value="Sig70_bacteroi1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="17"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="3">
        <location>
            <begin position="116"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD86997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="177" mass="20947" checksum="2B6D20D79385B5AC" modified="2019-11-13" version="1">MYKGKQHPRSLEGFKSLFDTLYPPLCLFANKYLNDMDTAEDIVQEVFIKVWEQDIQYINFYAAKSFFYKSVRNRCLDYLKSKYHRSVIQSPDIDFEKIVTEEFFLTQLTIIDTYSQLETAIKQLPTKCERIIRLSLNEYTIKEIADELAISKNTVKSQKRIAYEKLRHSLGSLLNIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE85</accession>
    <name>A0A5C6ZE85_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Trehalase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_13195</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha,alpha-trehalose + H2O = alpha-D-glucose + beta-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:32675"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15903"/>
            <dbReference type="ChEBI" id="CHEBI:16551"/>
            <dbReference type="ChEBI" id="CHEBI:17925"/>
            <dbReference type="EC" id="3.2.1.28"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004555">
        <property type="term" value="F:alpha,alpha-trehalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005993">
        <property type="term" value="P:trehalose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001661">
        <property type="entry name" value="Glyco_hydro_37"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018232">
        <property type="entry name" value="Glyco_hydro_37_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011120">
        <property type="entry name" value="Trehalase_Ca-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23403">
        <property type="entry name" value="PTHR23403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01204">
        <property type="entry name" value="Trehalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07492">
        <property type="entry name" value="Trehalase_Ca-bi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00744">
        <property type="entry name" value="GLHYDRLASE37"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00927">
        <property type="entry name" value="TREHALASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00928">
        <property type="entry name" value="TREHALASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Trehalase_Ca-bi" evidence="4">
        <location>
            <begin position="40"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD88260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="650" mass="74579" checksum="5358CAA46CA25D1E" modified="2019-11-13" version="1">MKTELKVILFGALVMISCKNETKQQTANGTIFKANIEQTLERLLAQEDTDGDKKITIEDKGPKVFELPSESGNTYKVEDTYKLSNLLQELVMAKNKGETVATLEMTYINEAPVTRTSRLIKDYYWDGLTRHLDKAGIESLIKDTKNQDLISNELTIYVPHNDTIAYRYYKSLESELPVKAIQLPATVTPEYVKSINEQPGILSLKLVKKNNELKGVPFVVPGGRFNEMYGWDSYFESVGLIVDGKVELAKAMADNFQYEIDYYGKILNANRSYYLTRTQPPFYSSLIREVYEVTKDKQWLKSHLITAIKEYETVWMVPGKRLVNTGLNRYLAEGIGVPPETEKGHFNALLKPYAEKAGLSIDVYLSNYTSGVIKSPELDAYFVQDRTVRESGHDTSYRIEGNCADLNLVELNAMLYKYETDFAQLIKTEFNDAFQTKAKTYTSDYFSIKAKRRQELSDQFLWNEKKGLYFDYNFKTNTPSNYVAATTLVPLWSKMASQEQAKRLVETALPLLKERGGIAASTEESRGEISDDRPERQWDYPNGWAPHQMMIWKGLLNYGYKDEAQELIYRWLYMITKNAVDYNGTIPEKYDVVEATHKVFAEYGNVGTDFEYITNEGFGWMNASYQYGLSLLEDGYLKDLNELKDPESIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE96</accession>
    <name>A0A5C6ZE96_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF4286 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_18440</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000031">
        <property type="protein sequence ID" value="TXD87037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025563">
        <property type="entry name" value="DUF4286"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14114">
        <property type="entry name" value="DUF4286"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="114" mass="13314" checksum="3553898A9D45B434" modified="2019-11-13" version="1">MIIYNVTINIDDSAHDEWLEWMKTEHIPQVLATGKFEKATFSKVLVEEDLGGITYSVQYRCKSREALNAYYKEDAEKLRAEGLKKFGDKQLAFRTEMEIVHEYDAGDEDFGFRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEA3</accession>
    <name>A0A5C6ZEA3_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Na(+)-translocating NADH-quinone reductase subunit B</fullName>
            <shortName evidence="13">Na(+)-NQR subunit B</shortName>
            <shortName evidence="13">Na(+)-translocating NQR subunit B</shortName>
            <ecNumber evidence="13">7.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">NQR complex subunit B</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">NQR-1 subunit B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">nqrB</name>
        <name evidence="14" type="ORF">ESY86_16520</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:47748"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="7.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="13">Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cell membrane</location>
            <topology evidence="13">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the NqrB/RnfD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.1.1" evidence="13"/>
    <dbReference type="EMBL" id="VORO01000023">
        <property type="protein sequence ID" value="TXD87498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016655">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022904">
        <property type="term" value="P:respiratory electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00426">
        <property type="entry name" value="NqrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010966">
        <property type="entry name" value="NqrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004338">
        <property type="entry name" value="NqrB/RnfD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30578">
        <property type="entry name" value="PTHR30578"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03116">
        <property type="entry name" value="NQR2_RnfD_RnfE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01937">
        <property type="entry name" value="nqrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="2 13" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 13" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 13" id="KW-0288">FMN</keyword>
    <keyword evidence="11 13" id="KW-0406">Ion transport</keyword>
    <keyword evidence="12 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 13" id="KW-0520">NAD</keyword>
    <keyword evidence="4 13" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0915">Sodium</keyword>
    <keyword evidence="13" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="8 13" id="KW-1278">Translocase</keyword>
    <keyword evidence="7 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 13" id="KW-0813">Transport</keyword>
    <keyword evidence="13 14" id="KW-0830">Ubiquinone</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="52"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="106"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="142"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="245"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="279"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="317"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="347"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="371"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="modified residue" description="FMN phosphoryl threonine" evidence="13">
        <location>
            <position position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TXD87498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="407" mass="44619" checksum="E2DEC1B0DF593162" modified="2019-11-13" version="1">MGLKNNLHTLKEKYKGKKMAPAFNALHTFLYLPNETTHNGTHIKAADDLKRTMNTVILALVPCLIYGMFNAGYQHYLALGEIEASHGFFASSFWTLDNLVVGLWQVLPLVVVSYGVGLAVEFVFAIIKGHEVEEGYLVTGMLVPLIVPVDIPLWMLAVAVVFGVVIGKEVFGGTGMNILNPALTIRAFLFFAYPTWMSGDKVWVHGAVERDQAIAAGQNLDAMSGETVLGSYAQSQDVAYSYADMFFGLIPGSVGETSKLLIIFGALFLIFTKVGSWRIILSTLVGALVMGLIFNGVVDAGWIGDTSKFYGLMSVPFWQHLIIGSILFGAVYMATDPVTASQTNKGKYIYGFLIGFLSIMIRVFNPAYPEGVFLAILLMNVFAPTIDHYVIQSNVKKRRKRLKLATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEA8</accession>
    <name>A0A5C6ZEA8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type IX secretion system membrane protein PorP/SprF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_14620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019861">
        <property type="entry name" value="PorP/SprF_Bacteroidetes"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11751">
        <property type="entry name" value="PorP_SprF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03519">
        <property type="entry name" value="T9SS_PorP_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022813294" evidence="1">
        <location>
            <begin position="22"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="335" mass="37639" checksum="1217AE21FD93B903" modified="2019-11-13" version="1">MNLKKYCLIAIAALFTQIGTAQEGLPIYSDYLTDNYYLIHPSMAGVANCAKVRLTARAQWFGQDEAPNLQTLSVNSRIGDSPSAVGAIVYNDKNGYHSQTGAYFTYAHHLMFSRNEIDLNMLSFGLSAGFIQYKLDETDFLADGFDPIIAGIEQSATNFNVDVGFSYHFIDFYAHATVKNLLDNDGINFNEQGLSYNNLRTYLVSLGNTFSKYGSPFSFEPSVMFMYRDATQEASFDVNLKAYREMDFGKVWGGLSYRRSLDGAQFQDGSGVSSQKLQYFTPFVGVDYNNFVFAYTYSYQANSVVFNNGGFHQITLGFNFNCRREKFECNCPAVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEB5</accession>
    <name>A0A5C6ZEB5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_16970</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000024">
        <property type="protein sequence ID" value="TXD87470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="5"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="41"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD87470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="227" mass="24823" checksum="1E1E4B080394ED65" modified="2019-11-13" version="1">MGNVIEIRNIIRDFQLGQETVHVLKGINLDIKTGEYVAIMGPSGSGKSTLMNLLGCLDTPTSGSYILNGKDVSQMSDDDLADIRNTEIGFVFQTFNLLPRTTALDNVALPMVYAGKSKAQRIERATEVLKNVGLADRMDHKPNQLSGGQRQRVALGRALVNNPSIILADEPTGNLDSKTGDEIMKLFDEIHQAGNTVIMVTHEEEIASNAKRIIRLRDGLVESDTFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEC2</accession>
    <name>A0A5C6ZEC2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">OmpH family outer membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_14655</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Skp family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.910.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005632">
        <property type="entry name" value="Chaperone_Skp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024930">
        <property type="entry name" value="Skp_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35089">
        <property type="entry name" value="PTHR35089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03938">
        <property type="entry name" value="OmpH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00935">
        <property type="entry name" value="OmpH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111384">
        <property type="entry name" value="SSF111384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022772634" evidence="4">
        <location>
            <begin position="24"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="42"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD87908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="169" mass="18746" checksum="351AC9EB4F31324C" modified="2019-11-13" version="1">MKHFKTLLFTALLFVGTTSIATAQSKIAHINTTELVQAMPEMKTAQAEIERLTKTYEAQIKEMATEIQNKVKQYQAEVDTKTEEENTSRSKEVQQMEQGIRQFQGQAQEDLGSKEAALYKPIFEKAKAAIEKVANAQGIQYVLDSTQGGGVLVADGKDLMADVKKELGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZED6</accession>
    <name>A0A5C6ZED6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">GLPGLI family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_13795</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005901">
        <property type="entry name" value="GLPGLI"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01200">
        <property type="entry name" value="GLPGLI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="258" mass="29768" checksum="9C79693D61663FBE" modified="2019-11-13" version="1">MEKFSLIFLLSTFCAFGQNISGVIKYKETLNLGDPVERHWSLYFDDNQSIYLETNSFETNSLTPDFKEKSEKTSNKSDELVINVDIDEFYVASSKTQSLKSQQIIAAEPYKVVEILPKIEWKLTEEKKKIKNFNCQKAVGYFRGRSYIVWFTEDIPTRFGPWKLSGLPGAILEFQDKTGQIKSIALKVELTSDLNIENIINSKAFIGKSLSIEAYVEKKQDENVLMLKYAMAKLGREANIQNVAPYEREGFELKYEWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEE8</accession>
    <name>A0A5C6ZEE8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Patatin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_13590</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="1 2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="3">
        <location>
            <begin position="10"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXGXXG" evidence="2">
        <location>
            <begin position="14"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="2">
        <location>
            <begin position="53"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="2">
        <location>
            <begin position="193"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="362" mass="40332" checksum="A7F968AD0C69BDA4" modified="2019-11-13" version="1">MEINQPKRILALDGGGIRGALTLGFLERLESIIREKENNKDLLLCDYFDLIGGTSTGAIIAAGLSIGKTAGEIKDLYLSIGEKIFGQKNSFWRNPRKWYKASYSYAPLEEALEDFFGDITMGSDRIKTGLCVVTKRADTFSTWPILSNPNGKYFKYNKNMMLHKVVRASAAAPTYFNPKQIDVGGGQIATFIDGGLSLANNPAFQLFLIATLKGFPYRWPLGEDKITLVSVGTGSSKKYIDANKVAKFGMLDWAKEIPNMFMEDANYLNQTVLQYLSNSPTAVHIDGEVGDLRDDILTDKPALHYLRYNVMLEENELNGLGMNFSLDEIKSLQKMDAAENKNKLYEIGAKAAVKYMKAEHIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEF7</accession>
    <name>A0A5C6ZEF7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_16615</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000023">
        <property type="protein sequence ID" value="TXD87516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002491">
        <property type="entry name" value="ABC_transptr_periplasmic_BD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01497">
        <property type="entry name" value="Peripla_BP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50983">
        <property type="entry name" value="FE_B12_PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe/B12 periplasmic-binding" evidence="1">
        <location>
            <begin position="17"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="262" mass="30497" checksum="A5A9A5F133052C0E" modified="2019-11-13" version="1">MKDQLGNLFKLASTPKRIVSLVPSQTELLVDLGLESSLVGITKFCVHPEELRNTKVIVGGTKQVHLDEIRGLKPDVILCNKEENTEEMVKELKSIAPVHISDVHTFEDALELIKMYGEMFSAAQKAQHLIEGIQKEKQQFSKFLKERPRYKVAYLIWKKPWMVVAKQTFIDEMLSLNNFENSFKDFERYPEIELAEIGERHPDVILLSSEPYPFKEDHQQDLEAIFPKTKIVLVDGEYFSWYGSRLLKAFDYFRKLHQNHLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEH1</accession>
    <name>A0A5C6ZEH1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_14005</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007235">
        <property type="entry name" value="Glyco_trans_28_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04101">
        <property type="entry name" value="Glyco_tran_28_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_tran_28_C" evidence="1">
        <location>
            <begin position="216"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="355" mass="40051" checksum="5CA6B798C2AC343D" modified="2019-11-13" version="1">MTSTSQKRILIAPLNWGLGHATRCIPIIKALVSQGLTPIIASDGAALALLRKEFETLTCIALPSYQIRYSKNAGFFKLKMLQNTPKILRAIKKEHRLTSELVKAHQIDGIISDNRFGVYHEDIPSVFITHQLQVLSGNTTWLSTRIQHKLIKRFDACWVPDVEDSSNLSGRLGHGSTSGLNIKYVGPLSRFSKKNTDFVYDLLILLSGPEPQRTLLEEKLLKELANHEGQILLVKGKVEEAQEVSEEKNWTSYNFMTSSQLEQAINASKLVVSRSGYTSIMDLSKLDKKAFFIPTPGQFEQEYLARRMAKLGLAPFCKQSEFNVAMLVEVERYKGLSHLDCPTDFKSLFSLFERE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEJ3</accession>
    <name>A0A5C6ZEJ3_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 7">ATP-dependent Clp protease proteolytic subunit</fullName>
            <ecNumber evidence="5">3.4.21.92</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Endopeptidase Clp</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">clpP</name>
        <name evidence="8" type="ORF">ESY86_14110</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 7">Belongs to the peptidase S14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.92" evidence="5"/>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07017">
        <property type="entry name" value="S14_ClpP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00444">
        <property type="entry name" value="ClpP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001907">
        <property type="entry name" value="ClpP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023562">
        <property type="entry name" value="ClpP/TepA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033135">
        <property type="entry name" value="ClpP_His_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381">
        <property type="entry name" value="PTHR10381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00574">
        <property type="entry name" value="CLP_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00127">
        <property type="entry name" value="CLPPROTEASEP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00382">
        <property type="entry name" value="CLP_PROTEASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5 8" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0720">Serine protease</keyword>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD88228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="181" mass="19843" checksum="E0999C81407D1B4C" modified="2019-11-13" version="1">MSKQVKAQDIIDGKLLEDRKVFLWGQVDDKSAKHVVDRLMYLDSLETKDIHLYINSPGGYVTAGFAIYDCIKSLNSEVSTICTGLAASMGSILLSVGAKGKRFIQPNAKVMIHQPSGGARGPASDIEITAQEILKTKELSAKILAENCDQTYEKIMKDFNRDHWMDAEESVAYGIVDGVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEK1</accession>
    <name>A0A5C6ZEK1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_16170</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="278"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="323"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="377"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="30"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="305"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD87572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="412" mass="46445" checksum="92F242CFEAF871E1" modified="2019-11-13" version="1">MNFEFFLAKRIIGSKAYKSSVSAPIIKIGISAIAIGMVVMLIAIATGLGLQKKVREKVVAFNGHITISKYDGNISNESIKSISTNQDFYPKFTSVEGIKHIQAVATKFGVIRTETDFEGIVLKGVGADYDWSYLEDFLVEGQLPKYGKGYSGDVVISSYLANRLQFELGDSFQTVFGKESIEEIPFQRRFKIVGIFNSGFNTIDKTFMIGDLAHIQRMNKWGKDQVGNFEIFLDDFSQLFQKETEIRNAIPPLLNTQNIEEKFQTTFEWIKIFDNNTYGIIAIMIIVAGINMITALLVLILERTQMIGVLKALGSNNWSIRKVFLINATYLIGLGLFWGNLIGLALLFAQQYFEILKFPNPEQYYVSVIPVHIGWDYLLLLNLGTFVACLAMMLIPSYIITKISPVKAMRFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEP1</accession>
    <name>A0A5C6ZEP1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_12240</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="206" mass="23243" checksum="9B6CA2B01EE78E10" modified="2019-11-13" version="1">MKNLIVIVAVLISGIVTAQTNYEKGMEQAFALWQDNKTDAAKNLFERISSAELDNWLPHYYIAQINSLESWDETDAQILKAKLDKAQEHLDLAMSMSKDNAELLVLQAQVLTNWVAFDGMTYGMKYSGKITELYQKAMALSPNNPRVVLGNAEWNMGSARYFGKDTKPYCKDVEKAIELFANFKPESEFAPNWGKAHAEAVFKSCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZES0</accession>
    <name>A0A5C6ZES0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_13155</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="98" mass="11170" checksum="5D4FDEB6E95DB3E5" modified="2019-11-13" version="1">MAKTSISIFFSIIFLSFILAPLVLMAIDDTADISCFYTISEEENKNGQKIKQAKLLVSVTPIEVELLYLQKSSNKTVYHFKNYPKPHLNLFSPPPEFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEU8</accession>
    <name>A0A5C6ZEU8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NifU family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_14605</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.70">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014824">
        <property type="entry name" value="Nfu/NifU_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036498">
        <property type="entry name" value="Nfu/NifU_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001075">
        <property type="entry name" value="NIF_FeS_clus_asmbl_NifU_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08712">
        <property type="entry name" value="Nfu_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01106">
        <property type="entry name" value="NifU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00932">
        <property type="entry name" value="Nfu_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110836">
        <property type="entry name" value="SSF110836"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="SSF117916"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nfu_N" evidence="1">
        <location>
            <begin position="6"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="Nfu_N" evidence="1">
        <location>
            <begin position="111"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="302" mass="33967" checksum="EA3478571EC137AF" modified="2019-11-13" version="1">MTTHKISIKPTTNPAILKFEAETFLTQQESFEFNNIDEASASPLAQELFYLPFVKKIYISGNFIAIERFNIVEWVDVQNEVSQQIEDYLNKGGAAVNSEATSNKTKVPVSIYAESTPNPSVLKFVANKKLVTNSHEFTSIDEAKYAPMATELFHFPFVKSVFIDENYVSITKFDMAEWNDITIELRDFIRNYIADAKTIINEDAPQVQQKKTEALDKTYEQLDDTSKEIINILEEYVKPAVASDGGNIEFQSYDPVSKTVKVVLQGACSGCPSSTYTLKSGIENMLREMMKGRVETVEAING</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEW0</accession>
    <name>A0A5C6ZEW0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glycosyl hydrolase family 30</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_16015</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 30 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000021">
        <property type="protein sequence ID" value="TXD87683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004348">
        <property type="term" value="F:glucosylceramidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006665">
        <property type="term" value="P:sphingolipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033452">
        <property type="entry name" value="GH30_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001139">
        <property type="entry name" value="Glyco_hydro_30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033453">
        <property type="entry name" value="Glyco_hydro_30_TIM-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11069">
        <property type="entry name" value="PTHR11069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02055">
        <property type="entry name" value="Glyco_hydro_30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17189">
        <property type="entry name" value="Glyco_hydro_30C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00843">
        <property type="entry name" value="GLHYDRLASE30"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Glyco_hydro_30" evidence="5">
        <location>
            <begin position="41"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_30C" evidence="6">
        <location>
            <begin position="407"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF17189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD87683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="472" mass="54085" checksum="235FD188712DD25B" modified="2019-11-13" version="1">MKFEVYETSESGKKLEKVTHFSSEGDAVSIKLNPKQKFQTITGFGGSFTEASAYLLNQLSEAKRNEVLEAYFGNDGAKYSLTRTHMNSCDFSLSNYSYAPIEGDVNLEHFSVEEDREDLIPMIKDAMAISEDGFKILTSPWTAPPWMKDNNSYVGGKLLPKYYDTWALFFSKYLEAYKAEGIDVWGFTVENEPLGNSNNWESMHFTAEEMTDFVQNHLGPKLEEDGHDAKILGYDQNRGEELNHWVDVMYANEASSKHYDGTAVHWYASTYDVFPESLEYAHNKAPNKYLIQSEGCVDSEVPKWKDDQWYWSKEATDWGWDWATAENKHLHPKYAPVNRYARDIIGCLNNWVDGWIDWNMVLNKQGGPNWFENWCVAPVIVDPQTDEVYYTPLFYTMSHFSRFIRPGAVRIGIENSDDELMATAVKNPDGSYVVVAFNETDTPKQIELTLEDQTIGLQISQRAIQTIVIPNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEX3</accession>
    <name>A0A5C6ZEX3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">8-amino-7-oxononanoate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_13665</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00599">
        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="3">
        <location>
            <begin position="28"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="386" mass="43030" checksum="CFB63633C6CD7567" modified="2019-11-13" version="1">MFPKKLQDKLDQRTAESSFRHLGQPNTLIDFSSNDYLGFSREKSIFDQAHRYLLEHELNQNGATGSRLLSGNHKLYEDVEAILSDFHKSESALIFNSGYDANLGFFTAVPQRNDLIFYDEFCHASIRDGIGMSQAKANKFKHNDIADLEQKLKRQFNKAFETNTLYVVTESVFSMDGDTPDLLRLSALCDAYNALLVVDEAHAIGVFGVNGNGIIPQLELEAQVFARIITFGKALGCHGAAVLGSKKLQDYLINFCRAFIYTTALPPHSLATLKFAYTALSNPPANPSAKAQLAENIHFFKAELKRLKLEQQFLDSDSAIQSCVVPGNEKVKKLAQQLQQNGFDVKPILSPTVPKGQERLRFCIHAYNSRDAISKVLQLLAIFTSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF02</accession>
    <name>A0A5C6ZF02_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">tRNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_17350</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000026">
        <property type="protein sequence ID" value="TXD87327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008231">
        <property type="entry name" value="CsaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002547">
        <property type="entry name" value="tRNA-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11586:SF37">
        <property type="entry name" value="PTHR11586:SF37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01588">
        <property type="entry name" value="tRNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02222">
        <property type="entry name" value="chap_CsaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50886">
        <property type="entry name" value="TRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 3" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="TRNA-binding" evidence="4">
        <location>
            <begin position="9"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD87327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="111" mass="12369" checksum="4595DF57ED88B55F" modified="2019-11-13" version="1">MDKIVSFKDFTKVDLRVGTIIEVLDFPKARNPAYQLTIDFGAFGIKKSSAQITERYTKEELLQKQVVAVLNFPKKQIANFISECLVVGAVEGKDVILLHPEQCIENGASVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF51</accession>
    <name>A0A5C6ZF51_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_11915</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the threonine aldolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001597">
        <property type="entry name" value="ArAA_b-elim_lyase/Thr_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023603">
        <property type="entry name" value="Low_specificity_L-TA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48097:SF9">
        <property type="entry name" value="PTHR48097:SF9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01212">
        <property type="entry name" value="Beta_elim_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017617">
        <property type="entry name" value="Thr_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Beta_elim_lyase" evidence="5">
        <location>
            <begin position="4"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="4">
        <location>
            <position position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR017617-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD88666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="341" mass="37371" checksum="73A44AA15A5955F4" modified="2019-11-13" version="1">MIIDLRSDTVTQPTKGMLEAMMSAKTGDDVYKEDPTVNALEARIADMFGMDTALFFPTGTMANQTALKLHTNPGDQVICDSNAHIYHYEGGGASFNSGISCKLLQGQGGTFTAQQVVEAINPPDFYHSPLTALVEIENTANRGGGTCWDFAEIKKIKTVCDQHNLGLHLDGARFWNALVAKKEDAKAYGKVFDTISVCLSKGLGCPAGTVLVGTETIMKNAIRIRKILGGGMRQTGYLAAAGLYALDHHLDRLAEDHIKAKEIEAVLTQLECVKQVQKVETNIIIFELNQNTDETHFLKTMASNHIRVSGMGNGKLRLVTHLDYTDAMHERFLEILKQLDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF56</accession>
    <name>A0A5C6ZF56_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">BlaR1 peptidase M56 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_14145</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008756">
        <property type="entry name" value="Peptidase_M56"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037682">
        <property type="entry name" value="TonB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05569">
        <property type="entry name" value="Peptidase_M56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03544">
        <property type="entry name" value="TonB_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="103"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="272"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M56" evidence="3">
        <location>
            <begin position="159"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_C" evidence="2">
        <location>
            <begin position="458"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_C" evidence="2">
        <location>
            <begin position="604"/>
            <end position="674"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="677" mass="77345" checksum="07E347743170304A" modified="2019-11-13" version="1">MIHYILQVVAFQLFFLIIYDFFLRKETFFNGNRAYLLGTTVLSVVIPFIKIDGIKTMVSHQFVVQLPAVIIGNTRQAPIIDPEVANLAGISIAPEPISMWSPIFFVGMGIAAALLLFKVVKLLGLYLKHPKRWSGNLRIIDLINSSAAFSFFNYVFLGERIQQQDRSAILEHELVHVKEKHTWDLLFFELLRIVFWFNPLVYMYQNRVATLHEYIADAKAVKHQSKSQYYDQLLAQVFETQQFSFVNPFFKQSLIKKRILMLSQSKSKQINLLKYALLIPLVFGMLFYVSCSKQSLMDDDPAAFDLSQYSYSLEKGGEKSPEIQKVHDAYEDFLINHPEYVGWAEIDEQDDVVSYSVHSVDDEVPEGYTEMGYMFPNGSTYISYMNFRPIGNSKVEREISVNHDYDGAEEVPFSVIDEVPTTKDCFENNNSNEDRRHCLSDFVASHVNKNFNINLATQLGLTGRQRIHVIFKINTEGDVVNVMARAPHPALEKEAIRVLKSLPQFIPGKHKGKLVMVPYSLPILFQVNTDDINTAPEESNTNETMYVEKIRFNTDRDLVEVPFSVVEEAPRFEGCENLFDNQAVQDCTSDAISAFVNKNFNTKLAKTAGLTGKQRINVIFKIDTNGDVIGIRSRAQSPILEREIERVIKMLPRFMPGKQKGKPVVVPYSLPVIFVEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFB6</accession>
    <name>A0A5C6ZFB6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">T9SS type A sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_13460</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023054143" evidence="1">
        <location>
            <begin position="19"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="domain" description="Por_Secre_tail" evidence="2">
        <location>
            <begin position="359"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="427" mass="46579" checksum="4AF54DF7ED8B9C6B" modified="2019-11-13" version="1">MKKTLLILALSLSLGVFAQNYTEYTTGSSTDISTNHEAGICLMGGATENDEAMLWFLNKANGGDVLVLRATGSDGYNDYFYSDLGVTLNSVTTFVINNAAGATDPVVLAKVANAEAIWFAGGDQFDYVSYFKDNAMETALNEFINVKQGVIGGTSAGMAIMGSSYFSGEFGTVESDVALSNPYHPRVTMGYNDFLEVPFMENVIADSHFADRDRQGRQSVFLARFVQDNGTRSFGIACNDYTAVCVEPNGKAYVYGEYPDYPEYAYFLQANCVSDYAPETVEAGTPVTWNRNGEAMKVYKVPGTYGGPNYFDLSDWETGFGGTWENWSIDNGTLSMLEGTNPQCATLDVSEVVANTIKVYPNPFDNLIQLESVAPISEVLLYDILGNVLPIQLKNDTTIDTSNLSSGLYILRLKTASGQQTLKLLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFH9</accession>
    <name>A0A5C6ZFH9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_11180</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD88794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="235" mass="26116" checksum="9B0438A7641C19BC" modified="2019-11-13" version="1">MVTIEGLHKKFGKQQVLSGLDLSISEGGIFAILGPNGSGKTTLIKTILGMVIPDKGEISVLGKNIKVNSEYRHKIDYLPQIANFPSNLKVKELIKMIKDLRKSTKEDERLIELFRLTPFLDKKLGTLSGGTKQKVNLVLTFMFDSPIVILDEPTSGLDPISLIRLKDLIQAEKAKGKTILITSHIMSFVEEVSDEIVFILEGKIYFKGSILELKTKTNQPDFEHAIASILTENHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFJ9</accession>
    <name>A0A5C6ZFJ9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GIY-YIG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12855</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035901">
        <property type="entry name" value="GIY-YIG_endonuc_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01541">
        <property type="entry name" value="GIY-YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82771">
        <property type="entry name" value="SSF82771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GIY-YIG" evidence="1">
        <location>
            <begin position="52"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="147" mass="16755" checksum="23C25D2D7FD0DFA3" modified="2019-11-13" version="1">MDTSGECRPDASGEPVTSCLPESYGVQLPLVRAQVGPLENPSSEGFFYYLGPMCHCYILFSNSLNRFYVGACQDLNKRIHNHNKGKYGKSTFTSTANDWVLFLNIETKNFPNARRLELKIKSMKSKTYVLNLKKHLELLEKIKREST</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFK2</accession>
    <name>A0A5C6ZFK2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Polysaccharide biosynthesis tyrosine autokinase</fullName>
            <ecNumber evidence="9">2.7.10.2</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_16940</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.10.2" evidence="9"/>
    <dbReference type="EMBL" id="VORO01000024">
        <property type="protein sequence ID" value="TXD87465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004715">
        <property type="term" value="F:non-membrane spanning protein tyrosine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045226">
        <property type="term" value="P:extracellular polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005702">
        <property type="entry name" value="EPS_synthesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032807">
        <property type="entry name" value="GNVR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13807">
        <property type="entry name" value="GNVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01007">
        <property type="entry name" value="eps_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0829">Tyrosine-protein kinase</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="521"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="domain" description="GNVR" evidence="8">
        <location>
            <begin position="461"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="domain" description="AAA_31" evidence="7">
        <location>
            <begin position="608"/>
            <end position="765"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD87465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="830" mass="93109" checksum="64ED848DC96BA4D3" modified="2019-11-13" version="1">MSEFDYQDREQSEPSGTTFDFRGYLFKVLNLWKFVLVCIGVALIIAYLINVRKPNVYKLSSLISVESEQNPFFTANTSISFNWGGVSGKTGKVMTTVKTRTHNELVVDSLQYYMNYLKEGKYRLEDIYKNAPFVVSLDQTKGQLLGQPIGIRFLGENQFEVFMEFESEGIQLQSYGSKEKMSGKVALGPFSKRFSFGETINLPFFNATIKAREGSSVAKGEVYYVNFLNYDSVVNKYQNDVAIAASAGNASAVLVLSLAGSNKAKIVDYLNATSAILSRTELERKNLYATNTIKFIDSSLNAVNDNLKDVTTEMNQFRTENKLFDITAEMGMISDKLRAFDLSKEAEKAKLSYLNSLENYLRTKTDYTKIAAPSSVGIEETNILSSVMKITALSIERQSKEYTVQEGNLIFKDIDRQIDAEKNVLLETISTTQQTIGINLNTINNNIARLESELGEMPEDQQQFLKIQRKMDISQEAYNIYLTKRGEAAIVKAANVSDISTIDEAKDIGGGRIGPNHSLNYMMALMLGFFSPMFLIFVVFLLDNTIHGSDEIQRLSNIPILGLIGKYNYKNNLVVFEKPKSAVAESFRSIRSSLQFLYKKQGKEGVGKTLMVTSSVSGEGKTFTSINIATVYALSGKKTILLGLDLRKPKIFGDFGMTNDRGMVNYLIGESTFEEIRSDSQIANLDVIPSGPVPPNPSELLMSDQLKHLIAELRQQYDMIILDTPPMGLVTDALELTQYADATIFMVRLDYTKKGMLSLINAKYRIGEVKNISFVLNFYKHKTNHNYGYGYGYGYGYGYGYGVYGNAYHESNRKKSLWGKFRKFINQTGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFX4</accession>
    <name>A0A5C6ZFX4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022793229" evidence="1">
        <location>
            <begin position="25"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="155" mass="16782" checksum="D57D79FDC7691FBC" modified="2019-11-13" version="1">MKLFKKTLLILAIFAGFTFQSCSSDDDSGSQNDDTYIRFTAGGEDFNYADPATAGSQNLTINGQNGNDNTVSTYSSVSIWFPLQITTGTYDFSGDFFQDGDYKLNLESTALNLDGWSETGSVIITAISSDYIEGTFTGTIEGVAITNGEFRAFNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG15</accession>
    <name>A0A5C6ZG15_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="15">ATP-binding cassette domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">ESY86_11600</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88610.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041552">
        <property type="entry name" value="UvrA_DNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17755">
        <property type="entry name" value="UvrA_DNA-bind"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 13 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0228">DNA excision</keyword>
    <keyword evidence="12" id="KW-0234">DNA repair</keyword>
    <keyword evidence="11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ABC transporter" evidence="14">
        <location>
            <begin position="731"/>
            <end position="1207"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="774"/>
            <end position="781"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TXD88610.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1501" mass="166721" checksum="784384085ED3985A" modified="2019-11-13" version="1">MKITNAHQNNLKNIDLDIPENCLIVVTGLSGSGKSSLAMGVIANEGYRYFLESLPAYNQQNGQMIPTAEVDEIQDLPPVIKVEQSKRFQSINATFGTLSELAAVFRIIFARYSGEETMSKSLFSFNHPKGACEVCRGIGEAEYIDLNKLIGDTHKTLREGAITTTLPNGYIVYSQITVEELNKVCKAHGFNVDIPWKELSDEQKEVVLNGSDRLKVFYGKHGLESRLRWQGIKAKPREEGYYKGMLPIMQDILRRDRNPNILKFSSSQVCPSCKGGRIKAEQLTYQWKGLNFQAWMELSLNDLYDQLNRLDLNAGEKLLVDKISTQLMDLIRLGMGHYQLSTASTSISSGDGQRIKLINQVNSNLQGILYVFDEPSIGLSANYQSYLLHILDRLIKRGNTVMVVEHDLEFIQAADWIVELGPEAGIHGGEVVFNGSIQDFLKAKHLNSPTLSALKTANAQTPSKSIKKPKKGSVTSFQPQANQLSVVSRKTPEFLERLKRYCEQEHLNLITVTDQPIGKTPRSNPATYTGLADKIRDLLAKTTEANSLNLGKSAFSFNNKKGRCEACEGAGVITLSMSVMGSINQICPTCNGKRFKTEVLRVHWKGKTIAAIYNLSIEEAHDFFSAEKNISETLSLMMQLGLGYIKLGQPSNTLSGGEAQRIKLTKHFAKKSKQTLLVLEEPSIGLHQQNVGQLLEALNQLKPQTAGILCFENHPLFQSACDICVDNALEVQAMDVKEEAPQQRELISIRGARTHVLKDLDLDFPKNRLSVVTGVSGSGKSSLVIDTLHGYGLQEMTKQFSAYQQSRVGVNFQFEVDHIEGLTPSICITRKQKNDSQRSDIAKQTGIDKILRFAFSRKAQYEGKELSASHFSNNHELGKCAVCEGLGQELLPDLNKLVLNPDKSIANGLFAHNKAIGYYADPKGQHMAILKVVGHEYGFTLETPFKALTPEQNEILLQGTGDKVWEADWVYQTKTREGTQALSMPWKGLFQYLQDDYFKTRKNKNTGHLTALFSYRECNHCEGSGLKPERLVFRIAGKSIHAIKAMDFKALGKWLSKTASPTKGIDGKLLSKIEPHLHNTITRAKELHIDHLQLNRKSPTLSGGENQRVALIKQLNSPLKGVTYLLDEPSAGLSQENIPDLIRILKELIDKGNTVIVIEHDKSIIHAADHIVQIGPKAGKLGGYMTYQGSPEGLLKQADCHPFLKTPSKAVQLKDGPTHINIRKLAKHSLKKDALALPIGGITALTGKSGIGKTTLVKDILIPSINTGQPVNCAGLDLPKTYAGAQYFEPKKLRTYANTLLVSYLDLLKDICNIFASETKLKPKDFSYKTKKSQCPNCKGKGFVETSLDITANAIETCEDCNGQRYQQHILAHEVQSKHIAEVLAMTILELKAWLRDFKVSASRFEFIKSLEAIGLAHLSLEQTVQSLSSGEKQRLLLLNWLQDSPKNELFVLDEPSTGLHYADIDLLYDILEKLSSDNDILVIEHNPYLLEKIGVGLVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG97</accession>
    <name>A0A5C6ZG97_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF6089 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_14675</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045743">
        <property type="entry name" value="DUF6089"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19573">
        <property type="entry name" value="DUF6089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022953267" description="DUF6089 domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="DUF6089" evidence="2">
        <location>
            <begin position="4"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="229" mass="25949" checksum="D02C4729B6891C1E" modified="2019-11-13" version="1">MRYLFLFILTIAFVPSSHSQIYEVGVFAGGSNFIGDVGATDYISPNAAAFGAIFKWNRSPRHSWRISFIYADLEGMDSKSDDPRRVQRDYSFDNSLLEISAGMEFTFFDFDLHTPGLKVTPYLYSGISTALHSNYYFDGNGKYTDENVKSWAYGIPMVLGVKSNITNHFVLGFEVGARYTFSDELDGSVPDGDFRENFSFGNTNSNDWYVFTGFTLTYTFGQRPCYCNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG98</accession>
    <name>A0A5C6ZG98_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Crp/Fnr family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="1">
        <location>
            <begin position="31"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="189" mass="21990" checksum="9E40E4C97F3B7107" modified="2019-11-13" version="1">MQQIKAYLEQIATISSEDWAFFMSKLQRRVIPKKTVFLKLHAIENHISFIESGVVRLFIPKEDSEKEITFGFSFKNQFVSAYDSFLTRQPSAYQLQALNETTLLSINYEDLQAVYKTTQIGNLIGRLTAERLFLIKSSREQNLLNLSAEERYVKIFKERPELLKVIPLKYISSYIGVTAQALSRIRKRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGH1</accession>
    <name>A0A5C6ZGH1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_09090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02522">
        <property type="entry name" value="GT_2_like_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026461">
        <property type="entry name" value="Trfase_2_rSAM/seldom_assoc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="6"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="264" mass="30155" checksum="BED2FC843BC74D13" modified="2019-11-13" version="1">MNHKISIIIPVLNEAESIGQLIQHLLHHSSSDEQVLEIIVVDGGSCDGSLDIVNRFSSEVHSSNLKPKLSDSDTLVTKKTSKPKTCLSTQIKLITSEKGRAKQLNRGAKEALGNILYFLHADSFPPKDFDSLIISEVNKGNLAGCFRMQFDSTHWWLQLASSFTQFPWRACRGGDQSQFITRALFDSIGGYDESYIIYEDNILINELYARKQFTVINKKLRSSARLYRKHGVWKVQYHFLRIYVKKWFGASAEELFGYYKEHLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGQ1</accession>
    <name>A0A5C6ZGQ1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_14180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_003446047.1">
        <property type="nucleotide sequence ID" value="NZ_VORO01000017.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="45"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="110" mass="12829" checksum="EC9E75BD9AA7A2A4" modified="2019-11-13" version="1">MVTKNKKMKMMTLDQMKDKDIGKIGTVERDKYEFELRMEVLGDMIKSVRKERNLTQEQLGELIGVQKSQISKLERNTKNVTIETILKVFKALKANVRFSVEMNESEFKVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH74</accession>
    <name>A0A5C6ZH74_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DegT/DnrJ/EryC1/StrS family aminotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_09835</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the DegT/DnrJ/EryC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00616">
        <property type="entry name" value="AHBA_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000653">
        <property type="entry name" value="DegT/StrS_aminotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30244">
        <property type="entry name" value="PTHR30244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01041">
        <property type="entry name" value="DegT_DnrJ_EryC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000390">
        <property type="entry name" value="PLP_StrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="184"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="367" mass="41380" checksum="5A04D193BF51FE90" modified="2019-11-13" version="1">MNQFIPISQPSITQKEIDYVNDAVTSTWISSLGKYIDRFEAEFAAFCGSRYAICVSNGTVAIQLALTAYGIGEGDEVIMPNLSFIATANATLHCGAKPVFADIDPSNLCLDPNAIEALITPKTKAIMPVHLYGHPAQMDAILKIANKHGLWVIEDAAEAHGATVNGKRVGSWGNCATFSFYGNKNLTTGEGGMITTDDEDFYNRCRHLRDHAMSKEKRYWHTAPGFNFRMTNIQAAIGCAQLERVADFMAKRQLIFDWYKTYLGDFKGVSLNNTDAWATNAYWLICLENKSWNLESRDAFMVELKKRGVDSRPYFYPMSQMPYINEFPDTPVTNQIYQQGINLPTYFDLKEEQVKFICEILRQLLDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHL5</accession>
    <name>A0A5C6ZHL5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UDP-2,3-diacylglucosamine diphosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_11770</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallophosphoesterase superfamily. YfcE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024654">
        <property type="entry name" value="Calcineurin-like_PHP_lpxH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043461">
        <property type="entry name" value="LpxH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34990">
        <property type="entry name" value="PTHR34990"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12850">
        <property type="entry name" value="Metallophos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos_2" evidence="2">
        <location>
            <begin position="8"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="290" mass="33706" checksum="7DB7A54097FE49BB" modified="2019-11-13" version="1">MKAKRKVEIAVISDVHLGTYGCHAKHLLTYLNSIAPKKLILNGDIIDIWQFSKRYFPKPHLKVIKKIMDMASDGVEIIYITGNHDEMLRKFSDTHIGNISIVDKIVLEIDGKRAWFFHGDVFDASIQNAKWLAKLGGYGYNLLIVFNQFMNWCLERMGKEKYSLSKKIKNSVKGAISYINDFEKVVADLAIEKGYDYVVCGHIHQPKMMLRETKHGKTIYLNSGDWVENFTALEYQFKRWKIYNYNQDKLRPFFEDHDLKEMDMKDLIAAITIVKPEKKSKKAKKSKDSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHQ4</accession>
    <name>A0A5C6ZHQ4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_13970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="341" mass="38379" checksum="4AC667AF887A53BD" modified="2019-11-13" version="1">MILVTGGTGLVGSHLLYDLLSKNECVKAIYRREHTLERVKTVFAYYNENVAELYNRIEWIEADLNDIPLLELAFKDVTHVYHCAAFVSFEPDKYNQLRKINIKGTANIVNLCIANNIEKLCYVSSIAALGNAPHPETPITETSDWNPEQDNSVYAITKYGAELEVWRGTQEGVDAVIINPGVILGPGFWKSGGSGSLFTSIYNGLRYYPEGSTAYVDVWDVVSAMQQLMMSSIKNESFILIAKNQSIQIFQETVAAALNVKKPNKKASPFLLAVAWRLDWLNHKVFGKRRKLSRHMANSITSETLYDNSKIKEALGFEFTGLEDSIKNVGSYFLKDFKETH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHR2</accession>
    <name>A0A5C6ZHR2_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ATP synthase subunit b</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">ATP synthase F(0) sector subunit b</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">ATPase subunit I</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">F-type ATPase subunit b</fullName>
            <shortName evidence="11">F-ATPase subunit b</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">atpF</name>
        <name evidence="14" type="ORF">ESY86_07755</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).</text>
    </comment>
    <comment type="function">
        <text evidence="10 11">F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cell membrane</location>
            <topology evidence="11">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11 12">Belongs to the ATPase B chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045263">
        <property type="term" value="C:proton-transporting ATP synthase complex, coupling factor F(o)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01398">
        <property type="entry name" value="ATP_synth_b_bprime"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028987">
        <property type="entry name" value="ATP_synth_B-like_membr_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002146">
        <property type="entry name" value="ATP_synth_b/b'su_bac/chlpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005864">
        <property type="entry name" value="ATP_synth_F0_bsu_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00430">
        <property type="entry name" value="ATP-synt_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81573">
        <property type="entry name" value="SSF81573"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01144">
        <property type="entry name" value="ATP_synt_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 11 12" id="KW-0138">CF(0)</keyword>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 11 12" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7 11 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 11 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="46"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TXD89668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="166" mass="18821" checksum="195C99B642E1C651" modified="2019-11-13" version="1">MGDLFNDFSIGLFAIQTVLLIVLILLMAKFAWKPIMNSLTEREEGIQGALDAADKARREMENLQADNQRLLQEARLERDTMFKEAREIKAKMIEDAKGEAQEQANSMIKQAQEAIESEKRNAMAELKNQVAVLSVDIAEKVIREELSNKSKQLELVDKMLGEARLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI05</accession>
    <name>A0A5C6ZI05_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type II toxin-antitoxin system ParD family antitoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08455</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.10.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022789">
        <property type="entry name" value="ParD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038296">
        <property type="entry name" value="ParD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36582">
        <property type="entry name" value="PTHR36582"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03693">
        <property type="entry name" value="ParD_antitoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02606">
        <property type="entry name" value="antidote_CC2985"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="83" mass="9273" checksum="6FF1A2A0A0230501" modified="2019-11-13" version="1">MSKNTSISLGDYFDQFVQNRITQGRFKNVSEVIRAGLRLLEEEESKVIALKMAIQEGIDSGVAHDFDPKKHLASLKAKKHSNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI19</accession>
    <name>A0A5C6ZI19_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HNH endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044925">
        <property type="entry name" value="His-Me_finger_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13392">
        <property type="entry name" value="HNH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54060">
        <property type="entry name" value="SSF54060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNHc" evidence="1">
        <location>
            <begin position="68"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="183" mass="22121" checksum="9EA3714683B1CCD5" modified="2019-11-13" version="1">MIRNYYKEEWKVIQFDEKIAENQKFKISNYGRLLKCSGPEEILVKQYYINGYQNLPIKQKLNGKQTSRYVHKLVAQHFLDKNDGVCVIHRDYDKTNNHIDNLKWATKREKEIHQFTNPEYKNRKRRIPYNAKLTETKVKLIKRKLNDPNRRTRLKMIAKQFGISEMQLHRIKTGENWGYVDAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI36</accession>
    <name>A0A5C6ZI36_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">3-methyl-2-oxobutanoate hydroxymethyltransferase</fullName>
            <ecNumber evidence="5">2.1.2.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Ketopantoate hydroxymethyltransferase</fullName>
            <shortName evidence="5">KPHMT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">panB</name>
        <name evidence="9" type="ORF">ESY86_06235</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + 3-methyl-2-oxobutanoate + H2O = (6S)-5,6,7,8-tetrahydrofolate + 2-dehydropantoate</text>
            <dbReference type="Rhea" id="RHEA:11824"/>
            <dbReference type="ChEBI" id="CHEBI:11561"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="EC" id="2.1.2.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="5 8">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantoate from 3-methyl-2-oxobutanoate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 5">Homodecamer; pentamer of dimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the PanB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.11" evidence="5"/>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00028">
        <property type="reaction ID" value="UER00003"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003864">
        <property type="term" value="F:3-methyl-2-oxobutanoate hydroxymethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06557">
        <property type="entry name" value="KPHMT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00156">
        <property type="entry name" value="PanB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003700">
        <property type="entry name" value="Pantoate_hydroxy_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20881">
        <property type="entry name" value="PTHR20881"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02548">
        <property type="entry name" value="Pantoate_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000388">
        <property type="entry name" value="Pantoate_hydroxy_MeTrfase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00222">
        <property type="entry name" value="panB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3 5" id="KW-0566">Pantothenate biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 9" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Alpha-ketoisovalerate binding" evidence="5 7">
        <location>
            <begin position="52"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5 6">
        <location>
            <position position="190"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7 8">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>3-methyl-2-oxobutanoate</name>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000388-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000388-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000388-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD89801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="272" mass="30005" checksum="9D7FE0AD810934CB" modified="2019-11-13" version="1">MSTAKKDYKRITVKSLVEMKQNHEKISMLTAYDYTMAKIVDGAGVDVILVGDSASNVMAGHETTLPITLDQMIYHASSVVRATERALVVVDLPFGSYQSDPKEALRSAIRIMKESGGHAVKMEGGKEVKESIKRILNAGIPVMGHLGLTPQSIYKFGTYTVRAKEEEEAQRLKDDALMLEKAGCFALVLEKIPAKLAEEVAKSVSIPVIGIGAGNGVDGQVLVLHDMIGMTYEFQPRFLRRYMNLYDDMTTAISQYVDDVKTVDFPSDSEQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI77</accession>
    <name>A0A5C6ZI77_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phytoene/squalene synthase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004311">
        <property type="term" value="F:farnesyltranstransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016117">
        <property type="term" value="P:carotenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00683">
        <property type="entry name" value="Trans_IPPS_HH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002060">
        <property type="entry name" value="Squ/phyt_synthse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019845">
        <property type="entry name" value="Squalene/phytoene_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044843">
        <property type="entry name" value="Trans_IPPS_bact-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033904">
        <property type="entry name" value="Trans_IPPS_HH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00494">
        <property type="entry name" value="SQS_PSY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01212">
        <property type="entry name" value="Phytoene_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01045">
        <property type="entry name" value="SQUALEN_PHYTOEN_SYN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="279" mass="32650" checksum="DC6CEDE6D1407854" modified="2019-11-13" version="1">MKSIFDSVSHKCSKVVTNSYSTSFSLATKMLSDSIRQDIYNIYGFVRFADEIVDSFHDYDKEMLFAEFNRALEMALEHKISLNPILNSFQETYHKYSIDKHLVDSFMKSMRTDLHKNTYLTDAEYKQYIYGSADVVGLMCLKVFVKGNQEKYDELKESAMSLGSAFQKVNFLRDLKADFEDLSRTYFPNTDLNHLDEASKQAIITDIENDFYKGLQGIKNLPIEAKFGVFMAYRYYSQLLKRLKKTPALEIKSTRIRVPNYKKFELLTRSYVKYQLNLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI96</accession>
    <name>A0A5C6ZI96_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribosome-associated translation inhibitor RaiA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">raiA</name>
        <name evidence="2" type="ORF">ESY86_10570</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044238">
        <property type="term" value="P:primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00552">
        <property type="entry name" value="RaiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036567">
        <property type="entry name" value="RHF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003489">
        <property type="entry name" value="RHF/RaiA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02482">
        <property type="entry name" value="Ribosomal_S30AE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69754">
        <property type="entry name" value="SSF69754"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00741">
        <property type="entry name" value="yfiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0810">Translation regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="100" mass="11704" checksum="2CAD87A59CCE3F4E" modified="2019-11-13" version="1">MKTNFEYHDVTASERLESYTEEKLQPIFKRYEFVTRADIFFKTENTSSDETGMKCGIRLSAPGPRLFAESSHANFEHAVSETVTELLRQLEKRQDKMKSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIG2</accession>
    <name>A0A5C6ZIG2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CPBP family intramembrane metalloprotease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="205"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="232"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="274"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="327" mass="37319" checksum="72DD71757674B54D" modified="2019-11-13" version="1">MFIAQAFKAKHDFWRYLVGSLIIFAAALVGQAPLTLAVIYRVWQDGGDLMNMNEGTIYSILDSNMLLFLLLLSFAVGFIGLFLAVKYVHNQTMTAVATSRPKLDWKRIWFAFLFWGIISSSLVLVDYFYLNPEAYVLNFEPQRFLILFVIAVALVPIQTSLEEYVFRGYLMQGFGMLAKNKWFPLLMTSVIFGTLHIANPEVGKLGYSLMVYYIGTGLFLGILTLMDEGTELALGFHAANNLFTALLVTSDWTAFQTHSILKDIAEPKLEFMDLVLPVFIIFPILLFIFSKVYKWTNWKEKLFGKVHEPPNEDYKIIGNNPTEYNSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIH5</accession>
    <name>A0A5C6ZIH5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nitronate monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12195</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018580">
        <property type="term" value="F:nitronate monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04730">
        <property type="entry name" value="NPD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004136">
        <property type="entry name" value="NMO"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03060">
        <property type="entry name" value="NMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NMO" evidence="1">
        <location>
            <begin position="3"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="316" mass="34145" checksum="0D6191997B9DAE3C" modified="2019-11-13" version="1">MSTRITELFGIQYPIIQAGMIWNSGWRLASAASNAGALGLIGAGSMYPEVLREHIQKCKKATDKPFGVNVPMLYPNIEDIMDIIVEEGVKIVFTSAGNPKTWTSWLKDRGITVVHVVSSLKFALKAQEAGVDAVVAEGFEAGGHNGREETTTLTLIPMVKEQLEIPLIAAGGIATGQIMLAVMILGADAVQVGSRFVASAESSAHINFKNTVVDAKEGATQLTLKELAPVRLIKNKFFHEIQALYEKGTTKDELIQLLGRARAKKGMFEGDLEDGELEIGQIAGLIHDIKPAAQIVADLVKEFEQALISARQIKIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZII8</accession>
    <name>A0A5C6ZII8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">UDP-4-amino-4, 6-dideoxy-N-acetyl-beta-L-altrosamine transaminase</fullName>
            <ecNumber evidence="4">2.6.1.92</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">pseC</name>
        <name evidence="4" type="ORF">ESY86_07930</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the DegT/DnrJ/EryC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.92" evidence="4"/>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00616">
        <property type="entry name" value="AHBA_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000653">
        <property type="entry name" value="DegT/StrS_aminotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020026">
        <property type="entry name" value="PseC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30244">
        <property type="entry name" value="PTHR30244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01041">
        <property type="entry name" value="DegT_DnrJ_EryC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000390">
        <property type="entry name" value="PLP_StrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03588">
        <property type="entry name" value="PseC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="193"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="381" mass="42622" checksum="01856B89EDF8A412" modified="2019-11-13" version="1">MKAIPYGRQHIEQDDIDAVVAALKSDFLTQGPKVQEFEDAFANYIGANYAVAVNNATSGLHLAVLALDLKPGDRVITTPITFAASANCIRYAGAEVWFADIDPDTYLLSLEKTRELIESYPKGFFKGIIPVDFAGLPLNMEAFRDLAEAHGLWIIEDACHAPGAYFTDSKDQKQRCGNGVYADMGIFSFHPVKHIACGEGGMLTTNSEALYKKLASLRTHGITKENMAENHGGWFYEMQELGYNYRLTDIQSALGISQLAKNDAGVKRRIDIAEAYKNAFRGKIKYQSLPNGSYNAHHLFIIEVDDRKGLYDFLKAQQIFAQIHYIPVHTLPYYKKIGYESADLSNSETYYSKCISLPMYPSLTDDEQRFVIEKVLTFVNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIL4</accession>
    <name>A0A5C6ZIL4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_12425</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010559">
        <property type="entry name" value="Sig_transdc_His_kin_internal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06580">
        <property type="entry name" value="His_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="His_kinase" evidence="2">
        <location>
            <begin position="166"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="352" mass="40593" checksum="1B91A016200BC083" modified="2019-11-13" version="1">MKLITNYKYWILNFIGWIAFAFLMLTIDKISSSVGPDSNRFYYLISEGFLCGFLGFALSFIILFYVENYFDVGDFSKRNIVGLVLVFTVTQIIYNVLLWPILDIPTAYFLDSSFEISFFSKLTNIPHFAAYFVVWLFVIFTIKIYYHINIIKLRQAQLQTSLKESQLNTLKGQINPHFMFNSLNNIRGLMLEDVDKSRRMLTSLSETIRYSLTKTNVTSIALEDELEMVQNYVEISKIQFEDRLQFETEIDEASLTKQIPPMIIQMLVENAIKHGISNLKNGGEVRLTTEVSSEYLKIEVINSGQIQKHQNGTQLGLKNIEQRLDLLYSNQATFSLTENAHQVIATIKIPLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIW2</accession>
    <name>A0A5C6ZIW2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fasciclin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02469">
        <property type="entry name" value="Fasciclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00554">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="SSF82153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50213">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAS1" evidence="1">
        <location>
            <begin position="13"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="160" mass="16319" checksum="F217873508065303" modified="2019-11-13" version="1">MENSNDKKTGQDTPNIVGVAAGNDAFATLVAAVKAAGLVDTLSGQGPFTVFAPTNDAFDKLPNGTVESLLKPESKDKLTAVLTYHVVAGKFEAAAVMDAIAKNDGKFTVDTVQGGQIHLGLKDGKVILTDANAGTATVVIADVAASNGVIHAIDTVVMPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIX8</accession>
    <name>A0A5C6ZIX8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_10745</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="386" mass="44039" checksum="29CACAE04345C5F9" modified="2019-11-13" version="1">MKFFPLALMALFLLTGCDGTENEVPSTFIGRYRISDQLVPYPYLIQQKKDSVYFYNSRGDLLDKVEHESLSSSSELEFKTSKFKIFRVSKQGFMAYDLKDSLTFRRFRGRPKLKNAAQFEKIASVTNLNVEAIRTSLEDAIWSYDLVADENTTPNTDLDIKQLMHFSADSLSIITSYYYQGLKTVSEFETKAFSVFKVGESCFLSFQKEADNPQPIYQIIAAEDGSIQLKDFSSREIKTITFKKQAMDPTQFLALADEATSYADCFDGYQGEYYFGDDVTFNKGNQYLMDFLNVDLPKTDSASGYVIVHFNINCQAKLGKFGLIQMDRNYQKTSFSKALVSHILKKVSQLEDWPSSQSQLAHLDYQDVHAFLMFKIGNGKITDLCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIY5</accession>
    <name>A0A5C6ZIY5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10805</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="62" mass="6036" checksum="D265462CDB45E42B" modified="2019-11-13" version="1">MPIKNDNHTSSSSSSSSSSSSSSSSSSSSNSTSNSTSNSSSSSSSSSSSTSSALILNKVAFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ77</accession>
    <name>A0A5C6ZJ77_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_06375</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="197" mass="23100" checksum="2D98C1F7D9DD73A6" modified="2019-11-13" version="1">MKNALLNSIPNLKPFNHDLHLNSVFIGKHWVLVNGLSEKKSVYVFEDDNILKISEAESVSKTSWNIDIKDVFSIETEDGLITVKAYFKDDDVLVLDHQDKPDFALFINESNYEEELNTVGDVRKFLRDKYKQKVTRLIYAHKFYYIENFKEFGPFTVEELSEKVKAEDISAYCFVRDINEADYSNRLRIWDLIKELG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ98</accession>
    <name>A0A5C6ZJ98_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_07585</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89639.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89639.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="63" mass="6681" checksum="9A047D725F4F1AA1" modified="2019-11-13" version="1">MAAVLLVCSSLNANAVVKQDAGCFEGADLAASALGGLYGYSYYQEYLLFNALYDNCESNGGWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJA6</accession>
    <name>A0A5C6ZJA6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_07640</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="72"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="226"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="271"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="72"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="198"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="554" mass="60314" checksum="D31A48A831F2606B" modified="2019-11-13" version="1">MSEKKNIDKLFKEQFKDFEVTPDDAIWKNIEQELHKDKRKRRIIPIWLKIAGVAALLALLFTVGQGVFNNDNNAIKNNPIVDSKSNTDTNASEGRNASNANAQNDSDNSQNANPSEQSDFSSKNGTQERVATTETNSDSLKTIENASEAASNGNQQSSEETQGSTAVVSNKDGEASTTRNALANASEEKAEPKKSAGQSENAVAQQQTLPQKEARLKSAAINQTEAIAQSQKPMNPEAKLAVENSDAEDSKSNALVSKENTASKIRIAAFNPEAKNNLETLTDNLQNQEENAIETAIALANDPEDLEDEDEAQQSKWSVSPNVAPVYFNSLGNSGSSLDAQFANNSKQGDVNVSYGIKGSYAINKKLKIRAGMNKVDLGYRTNNVLIFDSANTLGRSQTSLSNIELNAAESNNSFLSAKNVTFASAPDILFSKEQVSLDQNLGFIEVPIEIEYSVLNTKLGLNLIGGFSTFFLNNNEIFSVETNGNQTLMGEATNVNDLSYSANFGIGLDYELSKKLKVNLEPTFKYQLNTFNNTSGDFQPFFIGVYTGLSFKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJB0</accession>
    <name>A0A5C6ZJB0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SET domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06595</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SSF82199"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="1">
        <location>
            <begin position="4"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="194" mass="22670" checksum="94D408B7D70F09B1" modified="2019-11-13" version="1">MIHPHTEVKFINKTVGYGLVATQLIPAGTITWALDDLDREFSPEQFESMAAVYQDILETYTYRNNKGNLVLCWDNGKFVNHSFDSNCLTTAYDFEIAVRDIQPGEQLTDDYGYLNISEPFEGIDEGTYRKIVYPDDLLNYHHIWDEQLKKVFHHILKVEQPLRTFISHALWDKVQRVSTNKEEMTSIVKNYFPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJC8</accession>
    <name>A0A5C6ZJC8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Dipeptidase PepE</fullName>
            <ecNumber evidence="4">3.4.13.21</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">pepE</name>
        <name evidence="4" type="ORF">ESY86_05990</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S51 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.13.21" evidence="4"/>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016805">
        <property type="term" value="F:dipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03146">
        <property type="entry name" value="GAT1_Peptidase_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005320">
        <property type="entry name" value="Peptidase_S51"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03575">
        <property type="entry name" value="Peptidase_S51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0224">Dipeptidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0720">Serine protease</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD90284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="235" mass="26431" checksum="520BEA90AA311DC3" modified="2019-11-13" version="1">MKNIIIASTSALHGGGPLEYLLDELKLFFKDTPEILFIPYARPGGISYDDYTEKVSVPFKSIDKTVKGIHEFEDPKEAIKQAKAIFIGGGNTFVLVNQLYKNGLWEPIKNEVKNGTPYLGTSAGSNICGLTMNTTNDMPIVYPPSFKTFGFVPFNINPHYQDPDLNSKHIGETRETRIKEFHEFNSQPVVGLREGSWLEVKDKSIVLKGNLDARVFEYHKAAYEVKVDTELNILK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJL0</accession>
    <name>A0A5C6ZJL0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">M28 family peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_03740</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="PTHR12147"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="SSF49265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023133537" evidence="3">
        <location>
            <begin position="18"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M28" evidence="4">
        <location>
            <begin position="108"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="443" mass="49577" checksum="2A2F60A16C6DE589" modified="2019-11-13" version="1">MTKAFFIFLIAMSSVSAQTNLKIYDIIDKVSEESIRNDVKTLTEFGTRNTFSDTLSDTRGIGAARRWIKTEFETMSKACNSCLNVFYQKDFVTQEGNRRVPHDAWVVNVVAIQKGSKYPNRYIIMSGDIDSRASDTMDFTTDAPGANDNASGMAGTMEAARVLSQYQFENSIVYVGLSGEEQGLFGGAGLAAYAKENDWDIIGVFNNDMIGNIEGVDGVIDNRSFRIFSEPVPANETEKERNARRFYGGEVDGISRQLARYVHKTTETYMPEMNPMLVYRLDRFGRGGHHRPFNDLGFAGIRIMEAHENYTQQHQDIRTENGIDYGDTFEHVNFPYAKKLTTVNAINLASLAWAPPAPTQVAIGGIVEPSAKLKWNAVEAAKGYKIYWRDTTSPTWDHSRYVENVTEFTLEGIVIDNYFFGIAAVGENGFESVVAFPNAILRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJL7</accession>
    <name>A0A5C6ZJL7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_08385</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0675">Receptor</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="945" mass="105984" checksum="76819E53EF2339A9" modified="2019-11-13" version="1">MLSIFISFAQDTVVKGSVLDGTSGDPIPDVTITIEETTQSTTTDAKGEFQFKTIIPLGEQILKVEKIGYKTKRYPIVVNKGKTVDISGITLDYDQSDKKDLFIISISDDNLNSEDDGLTDNVSGLLQASRDVYLNAAAFDFSATFFRPRGLDNANGKVLINGIEMNKQFNGRPQWGNWGGLNDVQRNQEFTMGSTANDYTFGDLAGTNNIVMRASKYSEGGRFSYASSNRSYTDRVMASYSSGLLKGGWAYTILASRRSGEEGFVDGSLYDSNSFFAAVEKQINDKHSLNFTAIYAQNRRGRSTAITQEVFDIKGNTYNPFWGAQAGEIRNSRTRDILEPILMLNHYWDISSKTQLNTNLAYQFGKIGNTRIDNGGTRLSNFNGQPSYIGGARNPDPAYYQNLPSYQLRFDNLTSYNYQQAYLAEQSFRNDGQLDWTALYGANTRLRSNGTRLGNSTYAIQEDRNDDKQISINTIFDTDLTDRIRLNASLRFRKLKSENFAMLKDLLGGTGFLDVDFFAEELGPNSTLGLEDIAQSDRNNPNRIVQEGDRYKYNYDINANVFTGFAQLQFKYNKIDFYVGAHISQTNYQRNGLYENGNFIGSGPEGSFGKSDKLNFTNYGVKAGGTYKITGRHLIDLNASYFTKAPTIRNSFSNARQNNKIVSGLDSEQIQAIDLSYIFRSPIVKARLTGFYSGFENGTDIGFYYTEDLAGLGLDTGDAFVQEVMTNIEIRNLGAELGIEAQVTPTIKLKAAASAGQYIYNNNPNLYLSSDDFQAELRFGDGSTKIKNLHVAGGPEIAYQLGFEYRDPDYWWIGATSNFFSNAYLDVSNLSRSANFSTDYDGQPIADYDPEIAKTLLKQEQFDNYMLVNIVGGKSWKIDDYFVGFFATINNVFDKTYKTGGFEQSRLATYDRVLEDETRDTGEVFGSRYFFGFGTTYYLNFYVRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJQ0</accession>
    <name>A0A5C6ZJQ0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC transporter permease subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="227"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="260"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="438" mass="51326" checksum="E4BFE46AEF3A4E5D" modified="2019-11-13" version="1">MRSLQIFIYEWKHFTRSPFKIVALILFIVASMYGLHNGADLYEKQNNEFERLTQETETEIKTTLSYFENGKKGPDERPWVDNTQPFWAIYNAPTYAFKTPSPTIVYAIGQTEQYGFYKRINTWSNPYDADMTQEISNPERIQSGTLDFSFSILFLLPLLLLVLLYNIKGKEEEQGFLPLIFVQTGSKNWWIVSRTAFYTLLLLLVLVGVMVYGATLTNVFKANADSFWSILIYVTIYLLFWVIIYFLILKYSKSTVSNTLLMIGVWLLFAFIIPATIQQWIAIEKPTNLMVDLIDVKRDKTSEINEQSKALINRQMFELYPKLKETKTFKDTTIVRKRGGYSTNALVTIEMKNATKSIEEDNNAKNKLVETTYWINPITFFQNKLNKLTNTHYEDYESYRNAIQKSVDERTKIMVFDIWNDVTVDKEKYLEYNKTFSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJR5</accession>
    <name>A0A5C6ZJR5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fe-S cluster assembly protein SufB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">sufB</name>
        <name evidence="3" type="ORF">ESY86_08290</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0051 (ycf24) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010231">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000825">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037284">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045595">
        <property type="entry name" value="SufBD_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01458">
        <property type="entry name" value="SUFBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19295">
        <property type="entry name" value="SufBD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101960">
        <property type="entry name" value="SSF101960"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01980">
        <property type="entry name" value="sufB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SufBD_N" evidence="2">
        <location>
            <begin position="130"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="481" mass="53789" checksum="5B5BBCC68E8E569C" modified="2019-11-13" version="1">MKYTEDDLREELKTKEYEYGFYTDIESDTFPVGLNEDVVRAISMKKEEPEWMTEWRLEAYRYWESMIEPEWANVNYKKPDFQGISYYSAPNKKPKYESLDEVDPELLDTFKKLGISLDEQKMLAGVAMDVVVDSVSVATSFKKSLGEKGIIFCSISEAIREHPALVKKYLGTVVPQRDNFYAALNSAVFSDGSFCYIPKGVRCPMELSTYFRINQAGTGQFERTLLIADEGSYVSYLEGCTAPSRDENQLHAAVVELIALDDAEIKYSTVQNWYPGNAEGKGGVYNFVTKRGICEKNAKISWTQVETGSAITWKYPSCILKGDNSVGEFYSIAVTNNYQQADTGTKMIHLGKNTKSTIISKGISAGHSQNSYRGLVHISARADNARNFSQCDSLLMGNACGAHTFPYIEAKNKSAKVEHEATTSKIGEDQIFYCNQRGIDTEKAIALIVNGFSKEVLNKLPMEFAVEAQKLLEISLEGSVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJT9</accession>
    <name>A0A5C6ZJT9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">7-carboxy-7-deazaguanine synthase</fullName>
            <shortName evidence="5">CDG synthase</shortName>
            <ecNumber evidence="5">4.3.99.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Queuosine biosynthesis protein QueE</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">queE</name>
        <name evidence="7" type="ORF">ESY86_04665</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>6-carboxy-5,6,7,8-tetrahydropterin + H(+) = 7-carboxy-7-deazaguanine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:27974"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:61032"/>
            <dbReference type="ChEBI" id="CHEBI:61036"/>
            <dbReference type="EC" id="4.3.99.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </cofactor>
        <text evidence="5">Binds 1 S-adenosyl-L-methionine per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="5">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Purine metabolism; 7-cyano-7-deazaguanine biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the radical SAM superfamily. 7-carboxy-7-deazaguanine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.99.3" evidence="5"/>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00391"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016840">
        <property type="term" value="F:carbon-nitrogen lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904047">
        <property type="term" value="F:S-adenosyl-L-methionine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00917">
        <property type="entry name" value="QueE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024924">
        <property type="entry name" value="7-CO-7-deazaguanine_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000370">
        <property type="entry name" value="QueE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3 5" id="KW-0408">Iron</keyword>
    <keyword evidence="4 5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="6">
        <location>
            <begin position="31"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="25"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="5">
        <location>
            <begin position="50"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="5">
        <location>
            <begin position="127"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="44"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD90052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="210" mass="24129" checksum="46C52A26818DC6AA" modified="2019-11-13" version="1">MTRSERQDLIDQGLLLPLMEEFYTIQGEGFHKGTAAYFIRIGGCDVGCHWCDVKESWNAELHPPTETAKIVENAVKYSETIVVTGGEPLTWDMTELTKQLKAKGLQTHIETSGAYELTGEWDWICLSPKKMKLPTQKVYDKAHELKCIIFNKDDFRFAEEQAAKVNGDCILYLQPEWSKRDKMVPLIVDYVMANPKWKVSLQTHKYLNIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK49</accession>
    <name>A0A5C6ZK49_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Conjugal transfer protein TraK</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_05370</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="204" mass="23404" checksum="77D06C7BFEE77C9E" modified="2019-11-13" version="1">MKTPYKNIYNVLKLNRFIVLAVIVLAFLSSTFSLWMAFSTNKKALNSAFAINTDGSIIPLKLITQKENFQVEALAHLDLFHNYFYNIDASNYERNLEKALWLGNSSVDNLYRQKKADGVYNRLLQYSLVQKVLSIDSQVEEQNGTYVFRTVTVFEINRGSIIDTYELVSSGNLIPVDRNFPNNPHGLLITNYFENSLKKLNNES</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKJ6</accession>
    <name>A0A5C6ZKJ6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">KTSC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05035</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025309">
        <property type="entry name" value="KTSC_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13619">
        <property type="entry name" value="KTSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="SSF46565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="1">
        <location>
            <begin position="6"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="149" mass="17473" checksum="C55D662E8CFC4A82" modified="2019-11-13" version="1">MKRINEYKKLFGVENQVELKTLKKSYRDLVKAWHPDKFQNGDALQEEAEIQSRKIIDGYHFLVSIAPETIEANLPNYTETITNSGIADYVHKGLLLEITFLDGSTYEYFGVTKPVYIKMINSDKLNRFAKRNIYPNYIYRKSKRVLEEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKR6</accession>
    <name>A0A5C6ZKR6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_09345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydrolase_4" evidence="1">
        <location>
            <begin position="22"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="254" mass="28648" checksum="0F1DE1297A708FE2" modified="2019-11-13" version="1">MAHRLKKERDYSYIEVGEGKPIVVLHGLMGGLSNFDAVTNYFSSRGYKVLIPELPIYGMSLLKTNVKSFAKYLRDFIEHKGLEDVILLGNSLGGHIGLYHTKLYPEKVKALIITGSSGLYESAMGGGYTKRGDYEVIKKKAQDVFYDPKVATKAIVDEVYETVNDRNKLIKTLAIAKSAIRHNMAKDLPNMDLPVCIIWGRNDTVTPPEVAVEFDELLPDSELYWIDKCGHAAMMEHPDEFNTILSGWFEKRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKZ7</accession>
    <name>A0A5C6ZKZ7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_06505</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="521" mass="57430" checksum="01FFBA5AFE92342C" modified="2019-11-13" version="1">MKRILYFLFTGFIILFWSSCRNDFDFSPSTGGLEFSKDTIYLDTVFSNIGSSTYNLKVYNRSNEDISIPTVRLGEGQGSRYRLNVDGIAGKEFNDVELLAKDSLYIFVETTADIQSLSQNSLQFLYTDVIAFDSGTNFQKVELVTLVKDANFIYPNKNAATGIIETLSFDVDGDGEIDQTNLQGRFLEADELTFTNEKPYVIYGFAAVNAGDVLTIDAGARVHFHANSGLLVTNNASLKVNGELSIDQELLENEVIFESDRLEPGFANVPGQWSTIYLFNGSVANEINYATIKNATVGILTEGNQDAPNPKLSIRNSQIYNSSAFGILATASSITAKNLVLNNSGQSSFAGTGGGRYNFTHCSIANYWNTGFRQFPSLFLTNYVTGSDGNDVGNNLAEANFNNCIIYGNDNPELTFDELNGFDLNFKFTNCLIRFQDTNGNFIGENYNFSNTDRYENCILNGEPDFKAPFENELMIGNASAANGQGNSDFANQVPFDILNTGRTASPDLGAYQHLTFEDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL28</accession>
    <name>A0A5C6ZL28_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CinA-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_03955</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CinA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00885">
        <property type="entry name" value="cinA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00226_B">
        <property type="entry name" value="CinA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036653">
        <property type="entry name" value="CinA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008136">
        <property type="entry name" value="CinA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041424">
        <property type="entry name" value="CinA_KH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008135">
        <property type="entry name" value="Competence-induced_CinA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02464">
        <property type="entry name" value="CinA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18146">
        <property type="entry name" value="CinA_KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006728">
        <property type="entry name" value="CinA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00852">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142433">
        <property type="entry name" value="SSF142433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="SSF53218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00200">
        <property type="entry name" value="cinA_nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00177">
        <property type="entry name" value="molyb_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00199">
        <property type="entry name" value="PncC_domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MoCF_biosynth" evidence="2">
        <location>
            <begin position="4"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="415" mass="45816" checksum="470113BD5D93AA3A" modified="2019-11-13" version="1">MLAEIITIGDEILIGQIVDSNSAFIAKQLNKIGVSVYQITSVQDDKNHILKALAEAEANADIIILTGGLGPTKDDITKKTLAHYFDDHLVEAVAVRKNIEHLWEHYIKRPLMQVNIDQALVPSKCSVLMNKLGSAPGMWMEKNDKIVIALPGVPYEMKALIDDEVIPKLRNRYQFPYIQHKTFLTYGLGESALAEHIETFENELPTFIKLAYLPSLGRVRLRLSAKGINRELIEKEMQIQTDLLLPQIKDIFTGFEEDGSIEDIVGKHLTEQGRTVATAESCTGGLIASRFTANAGASKYFKGSVVTYSKETKMQLLNIPEALIDAHSVVSIEVAEAMALNALKLFKTDFAISTTGNAGPTKDHTQEGLGDVYIAIANKDGVFSAKFSFGNSREKVINKAANKAFELLLKEILKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL42</accession>
    <name>A0A5C6ZL42_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF4974 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_06775</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006860">
        <property type="entry name" value="FecR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012373">
        <property type="entry name" value="Ferrdict_sens_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30273">
        <property type="entry name" value="PTHR30273"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04773">
        <property type="entry name" value="FecR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018266">
        <property type="entry name" value="FecR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="FecR" evidence="2">
        <location>
            <begin position="101"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="301" mass="34218" checksum="A06114E389662B48" modified="2019-11-13" version="1">MDKEYLIKKWLDNELSEAETQAFKALEDADFYKEIIQEAQRFGGEQHAKVKPFETIESKLYTKDVPARHWLKIASGIAAVFVLGIAVFMLLDKDKINMFDTNYAQSETITLPDNSIVKLNQLSHLEYNASNWDKNRIVVLKGEALFNVEKGQRFDVTTQFGKVSVLGTEFNVLSRDSIFKVSCYEGLVQVSYGTDSIKLPAGTEFVLKSGNAKTTEIAITEPYWLKNMSVFENASINAVIKEIETQFDIGILKEFDEKDVMFTGAFEHNNLENALKSITQPLNLTYEIINNKEVIIRNVKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL47</accession>
    <name>A0A5C6ZL47_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidoglycan DD-metalloendopeptidase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_08015</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M23" evidence="2">
        <location>
            <begin position="186"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="288" mass="32390" checksum="E4B6C6EFA4FF3798" modified="2019-11-13" version="1">MAKTEKNKKFKKKLLHKYRLVVLNEDTFEERFAIKLTRLNVFVIVAISSILLVAGTIFLIAFTSLKEFIPGYSSTALKKKATFLNYKTDSLQNVINLNEQYYGSIKKVLTGDIKAVNINKDSLIEAAKIDADNINLTPSKEDSILRELVDKEDKYNLFDAAKSTSNFVLFPPVNGQISEGYDIKNKHYAVDIVVPNNTPVKATADGTIIFAEWTIETGYVIIIEHSYELISVYKHNASLTKEQGDLVKSGEVIAMTGNTGELTTGPHLHFELWNRGYPLNPTNFIDFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLE5</accession>
    <name>A0A5C6ZLE5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Inorganic pyrophosphatase</fullName>
            <ecNumber evidence="5">3.6.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Pyrophosphate phospho-hydrolase</fullName>
            <shortName evidence="5">PPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ppa</name>
        <name evidence="6" type="ORF">ESY86_02500</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>diphosphate + H2O = H(+) + 2 phosphate</text>
            <dbReference type="Rhea" id="RHEA:24576"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="EC" id="3.6.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.1" evidence="5"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006796">
        <property type="term" value="P:phosphate-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00412">
        <property type="entry name" value="pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00209">
        <property type="entry name" value="Inorganic_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008162">
        <property type="entry name" value="Pyrophosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036649">
        <property type="entry name" value="Pyrophosphatase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10286">
        <property type="entry name" value="PTHR10286"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00719">
        <property type="entry name" value="Pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50324">
        <property type="entry name" value="SSF50324"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <position position="22"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD90849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="175" mass="20002" checksum="08A5D72BF39F53CA" modified="2019-11-13" version="1">MTANGKLTFDVLIEIPKGSRNKYEYDFDLKKIRFDRMLFSSMMYPADYGFIPETLALDGDPLDVLVLGGEPTFPMIVMEVKPIGVFHMADEKGPDEKVICVPVSDPIWNSLNDLADMNPHQIKEIEHFFQVYKDLEKKKVDVGGWGNADKAYEILNSCIERYEKSDKDKTGHFSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLJ5</accession>
    <name>A0A5C6ZLJ5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Phenylalanine--tRNA ligase beta subunit</fullName>
            <ecNumber evidence="14">6.1.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Phenylalanyl-tRNA synthetase beta subunit</fullName>
            <shortName evidence="14">PheRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">pheT</name>
        <name evidence="19" type="ORF">ESY86_00715</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) + L-phenylalanyl-tRNA(Phe)</text>
            <dbReference type="Rhea" id="RHEA:19413"/>
            <dbReference type="Rhea" id="RHEA-COMP:9668"/>
            <dbReference type="Rhea" id="RHEA-COMP:9699"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58095"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78531"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="14">Binds 2 magnesium ions per tetramer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 14">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 14">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.20" evidence="14"/>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006432">
        <property type="term" value="P:phenylalanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00769">
        <property type="entry name" value="PheRS_beta_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02796">
        <property type="entry name" value="tRNA_bind_bactPheRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00283">
        <property type="entry name" value="Phe_tRNA_synth_beta1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005146">
        <property type="entry name" value="B3/B4_tRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005121">
        <property type="entry name" value="Fdx_antiC-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036690">
        <property type="entry name" value="Fdx_antiC-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045060">
        <property type="entry name" value="Phe-tRNA-ligase_IIc_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004532">
        <property type="entry name" value="Phe-tRNA-ligase_IIc_bsu_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020825">
        <property type="entry name" value="Phe-tRNA_synthase-like_B3/B4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041616">
        <property type="entry name" value="PheRS_beta_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002547">
        <property type="entry name" value="tRNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033714">
        <property type="entry name" value="tRNA_bind_bactPheRS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005147">
        <property type="entry name" value="tRNA_synthase_B5-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10947">
        <property type="entry name" value="PTHR10947"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03483">
        <property type="entry name" value="B3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03484">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03147">
        <property type="entry name" value="FDX-ACB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01588">
        <property type="entry name" value="tRNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17759">
        <property type="entry name" value="tRNA_synthFbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00873">
        <property type="entry name" value="B3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00874">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00896">
        <property type="entry name" value="FDX-ACB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54991">
        <property type="entry name" value="SSF54991"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00472">
        <property type="entry name" value="pheT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51483">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51447">
        <property type="entry name" value="FDX_ACB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50886">
        <property type="entry name" value="TRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 14" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="9 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 14 19" id="KW-0436">Ligase</keyword>
    <keyword evidence="10 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12 14" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 15" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 15" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="TRNA-binding" evidence="16">
        <location>
            <begin position="42"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="B5" evidence="18">
        <location>
            <begin position="414"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="domain" description="FDX-ACB" evidence="17">
        <location>
            <begin position="715"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="468"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="474"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="477"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="478"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="TXD91144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="808" mass="90152" checksum="F388B468A5669B07" modified="2019-11-13" version="1">MKISYNWLKQFLKTDWPAERTGELLTNLGLEIEGIEPYQTVKGGLEGIVVGEVLTCVQHSNADRLKVTTVDIGAESPLQIVCGAANIAVGQKVPVATIGTTLYSAEGEPWTIKKGNIRGESSHGMICAEDELGLGNSHEGILVLDAKTKVGTPAAQLFEIENDQVFEIGLTPNRADAMSHFGVARDLKAGFVQQGLNTELITPSVSAFHVENRTLKIDIDVKNSDLAPRYCGLTISGIKVADSPKWLQNRLKAIGITPKNNVVDITNYVLHELGQPLHAFDAAKIVGNKVIVKTLPEGTKFQTLDGIERELSAEDLMICDAEKPMCIAGIFGGIHSAVNEHTTSIFLESAYFNPVSIRKTAKRHALNTDASFRFERGIDPKITEYALKRAAIMIQDIAGGDVTSDLLEYYPKKIEDFQVRVSFENARKLIGEDIPKETIKSILTSLEIKINNVTETGLGLTVPAYRNDVQREPDVIEELLRVYGYNKIKTTEKLNASISNTSKFEDYKLQNVIGNQLASQGFFEILSNSLTTPKYAALSDQLKAEHNVEMLNPLSHDLSVMRQSLLFSGLETVSHNLNRKREDLKLFEFGKTYHNYNGTHEENKHLSFLLTGDKTKQRWNSTASPSDFFYLKGTIEAVLMRLGLSNYKTAPVKNDVFSEGISLSLGKNHLVDFGIVQKRILKHFGIDQEVLFADFNWDSVIDMAKHNKVNFQNVTKYPEVRRDFALLLDHAVSFEQIDAIANKTEKRLLKDVDLFDVYQGENLPEGKKSYAVSFVFQDEQTTLTDKQIDKIMSKLQSNFERELGAELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLP0</accession>
    <name>A0A5C6ZLP0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FeoB-associated Cys-rich membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="48" mass="5273" checksum="EA3DD896E74B6609" modified="2019-11-13" version="1">MNTIIQNILVFSALAYAIWYLLRKFGILPKRKKASSKACGGDDGCGCH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLS6</accession>
    <name>A0A5C6ZLS6_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Abasic site processing protein</fullName>
            <ecNumber evidence="7">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_01255</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the SOS response-associated peptidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="7"/>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:cellular response to DNA damage stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018142">
        <property type="term" value="P:protein-DNA covalent cross-linking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1680.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003738">
        <property type="entry name" value="SRAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036590">
        <property type="entry name" value="SRAP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13604">
        <property type="entry name" value="PTHR13604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02586">
        <property type="entry name" value="SRAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143081">
        <property type="entry name" value="SSF143081"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0190">Covalent protein-DNA linkage</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD91244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="235" mass="27296" checksum="11D1E1D46C9284B0" modified="2019-11-13" version="1">MFYKLTNSSELETIEEEFSRKHNFPNLYKSKTILNGLKEVTVSIITAQDPDQINHAIWGLLPKDFDDDWKSYQSVDNTLNINLDKVDASDELYYNALTTNRCIVITSGFFTSRLHEGKLFPYHVHLKDHRPFGIAGVYNMLEDGFITCSILITKANRAFENIPNLSKNKPLVFKNGDFSKWLDTSKSYQDQMPLIQNHETLEFLSYPIKEEFYRDSGVYDTIIESADYYDILRTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLT1</accession>
    <name>A0A5C6ZLT1_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TSPc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_05580</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022704721" description="TSPc domain-containing protein" evidence="1">
        <location>
            <begin position="20"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="domain" description="TSPc" evidence="2">
        <location>
            <begin position="566"/>
            <end position="708"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="765" mass="88089" checksum="094C9A66D6416D31" modified="2019-11-13" version="1">MKHFLLSIVFLSFSLVSEAQTTGYFKHLVFRETPYSEIKGRIPLTEEEAQNVNHFKLSYDLSNRLIRIEYLYKEIRIDLNRSGILDGKRALAPKTEITYTTDTETRMFFDIDGKPTTNGMGVFKEVYSYNKKGKRIGLKFFDKNDEPINNSWNIFEYTWKHIDNNSVFETRKNVGGADVSMRPYYKFYNVLYKFDDDGLLLSMNNVDSKLKLLNDETGIAIDKATYDKNNNLVSFKFFNAENKPVVGSFLGSAGGFATYDKNGNCLKYATVDLDGNLKMSTRSNDAYSKYTFDSIGNLIERSSYDTNNKILKKRDVTSVKYVYETENPVQLLKTELYHTIPNKTAKDSILESLNKKTEKDKLVEDFNQLLETLKEHPAQFEFIDKTAYEKLVNYQREKIKDSMTVTEFYQVTSPIVASLGCLHTRIVDTRFFRTPQKYWLPLIVWFEDEKMYAINNCVENIEMNAGSEILEINGVSSNEIFKILKTTISADAYNQSFYRGDLNVNFLYYYHSYYGFDSEYRIKFKPYNSEKIITTSFLIDEPAPAYKEEINNKPILGIDINKENRTAIIKIKNFNFFPRGRQNIDYFKETIDAYMKQIKDENIPKVAFDLRGNRGGNPECTNHILSYITNTEIDFYEDNELNKSRDRTISVTPKSDNNISGKNIFILTDGRCASATAQMLAVIKHNQLATIIGEETGGTYSTHPGRGVTALKNTKLGLQIGTERESVNVPNLELDKGIIPHKEIELKLSDIINGEDPLLNYILKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLZ9</accession>
    <name>A0A5C6ZLZ9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_00560</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039426">
        <property type="entry name" value="BtuB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30069">
        <property type="entry name" value="PTHR30069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0675">Receptor</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="domain" description="Plug" evidence="6">
        <location>
            <begin position="83"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="5">
        <location>
            <begin position="250"/>
            <end position="729"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD91328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="734" mass="81835" checksum="54398105BFC6D4B0" modified="2019-11-13" version="1">MANETPLANAFIINTKTKDTLISNKNGNFNITDFGSYLLQKPGYFSKTVQFSQNDYRIVSLQINPQQLGEVVFNTNHVPKPLKKATAAINIVTSKDIERANNINFSPVLNRVPGVFMQSGTLSTNRIVIRGIGSRTLYGTSKIRAYFKDIPLTNGSGETNIEDFELGSISSFEIIKGAVSSIYGAGLGGTIHLKPESATFNQTSFSTELTLGSFGLVKSLNELNYGASKSNYKVVYSHTESDGYRDNNNYNRETLTLNSNHYLGEKDELSFLGSYVDLKAFIPSSINASDFENRPKTAALNWKQAQGYEAAKRGIFGLSWKHQYSSSLNQNTSIFTSFRDAYEPRPFNILTENSFAFGIRTRLLGDIKLLEKDLNWTLGAEVFREHYRSKTFENLYEAFPIGTGSVQGAKASDFKEKRDYYNLFFEGNYEFSEATTLSVGLNMNQTGYDLTDDFAVSEENPDQSGNFQFKTILSPKFGVSHLFSEAISAFASISHGFSPISSAETLLPDGQINTQLKPETGWNFELGTRGTSLDNRLNYSLNIYRLDVKNLLVARRVGQDQYIGVNAGRTQHDGLELSAEYQWFQSADFTLSSFANYSLNHYKFKEFIDDGQNFSGNELTGVPNGIFNAGVDVTSKIGFYGNINFQQVGKMPITDSNNLYSNAYSLTNLKIGYAPKLSEQLQLNLFFGLNNIFDTAYASQILINANSFGNAAPRYYYPGEPSNYFSGISLNYVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM80</accession>
    <name>A0A5C6ZM80_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF2147 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_00120</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019223">
        <property type="entry name" value="DUF2147"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09917">
        <property type="entry name" value="DUF2147"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022676845" evidence="1">
        <location>
            <begin position="20"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2147" evidence="2">
        <location>
            <begin position="24"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD91042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="141" mass="16296" checksum="A6904CE5DB376A0A" modified="2019-11-13" version="1">MNKPILSILAMCICSLTFAQEIFGNWKTIDDETGKERSIVNIYKENGKVYGKIVEIFDASKRDLNCVKCEGEDYNKPVLGLIIIKDMEKDEDAYREGTITNPDDGKVYDCRLKLTDDPNELQVRGYVAFFYKTQYWVRADK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZME0</accession>
    <name>A0A5C6ZME0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ATP-binding cassette domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_03645</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030296">
        <property type="entry name" value="MlaF/Mkl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43023:SF6">
        <property type="entry name" value="PTHR43023:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="11"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="43"/>
            <end position="50"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="250" mass="27977" checksum="FFF188B116DC11F3" modified="2019-11-13" version="1">MNSEKNIKPVLELKNLKKSFGDNHVLKGFNLKLFEGENLVIMGKSGSGKSVMVKCLVGLIQPDSGNITIKNQDITTMGQTELDLLRTEIGFLFQGSALYDSMTVRENLEFPLRRHKDKIENFQGTEFSVKEALENVGLANAIDLMPAELSGGMQRRVAMARALILKPKIIMYDEPTTGLDPITAKEIIQLMRSIQEKYNTSSIIITHDVDCARVISNRMILLVDGTNYAEGTFEELSNSKDEQIQAFFKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMJ4</accession>
    <name>A0A5C6ZMJ4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 14">Inosine-5'-monophosphate dehydrogenase</fullName>
            <shortName evidence="7">IMP dehydrogenase</shortName>
            <shortName evidence="7">IMPD</shortName>
            <shortName evidence="7">IMPDH</shortName>
            <ecNumber evidence="7 14">1.1.1.205</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 16" type="primary">guaB</name>
        <name evidence="16" type="ORF">ESY86_06600</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 14">
            <text>H2O + IMP + NAD(+) = H(+) + NADH + XMP</text>
            <dbReference type="Rhea" id="RHEA:11708"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="EC" id="1.1.1.205"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="7">Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7 14">Purine metabolism; XMP biosynthesis via de novo pathway; XMP from IMP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 13">Belongs to the IMPDH/GMPR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.205" evidence="7 14"/>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00601">
        <property type="reaction ID" value="UER00295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003938">
        <property type="term" value="F:IMP dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006177">
        <property type="term" value="P:GMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00381">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01964">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005990">
        <property type="entry name" value="IMP_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015875">
        <property type="entry name" value="IMP_DH/GMP_Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001093">
        <property type="entry name" value="IMP_DH_GMPRt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11911">
        <property type="entry name" value="PTHR11911"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00478">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000130">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01302">
        <property type="entry name" value="IMP_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00487">
        <property type="entry name" value="IMP_DH_GMP_RED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0129">CBS domain</keyword>
    <keyword evidence="3 7 14" id="KW-0332">GMP biosynthesis</keyword>
    <keyword evidence="2 7 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10 14" id="KW-0520">NAD</keyword>
    <keyword evidence="5 7 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 7 11" id="KW-0630">Potassium</keyword>
    <keyword evidence="7 14" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="15">
        <location>
            <begin position="97"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="15">
        <location>
            <begin position="157"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="IMP binding" evidence="7 9">
        <location>
            <begin position="341"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="IMP binding" evidence="7 9">
        <location>
            <begin position="364"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="region of interest" description="IMP binding" evidence="7 9">
        <location>
            <begin position="388"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="active site" description="Thioimidate intermediate" evidence="7 8">
        <location>
            <position position="308"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7 8">
        <location>
            <position position="404"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="251"/>
            <end position="253"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 10">
        <location>
            <begin position="301"/>
            <end position="303"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 11">
        <location>
            <position position="303"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 11">
        <location>
            <position position="305"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="306"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 11">
        <location>
            <position position="308"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="419"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="473"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="474"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="475"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="TXD89867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="490" mass="52384" checksum="62AE16F248A68238" modified="2019-11-13" version="1">MTAHENKIVGEGLTYDDVLLVPAYSEVLPREVNIQTKFTRNITINIPIVSAAMDTVTESKMAIAMAQEGGIGVLHKNMSIEQQAEKVRRVKRAESGMIIDPVTLPMTARVIDAKQNMAEHGIGGIPIVDENGRLKGIVTNRDLRFEHANDRPIVEVMTSENLITAAVGTSLKGAEKILQQNKIEKLLIVDDNYKLVGLITFRDITKVIQKPNANKDSFGRLRVAAAIGVTPDAVERASALVHAGVDAVIIDTAHGHTKGVVLVLKDIKKKFPELEVIVGNIATAEAAKYLVDAGADAVKVGIGPGSICTTRIVAGVGFPQFSAVLEVAAAIKGSGVPVIADGGIRYTGDIPKAIAAGADCVMLGSLLAGTKESPGETIIYEGRKFKSYRGMGSVEAMKQGSKDRYFQDVEDDIKKLVPEGIVGRVPYKGDLVESIHQFIGGLRAGMGYCGAKDVATLQNTGRFVKITSSGINESHPHDVTITKESPNYSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMW8</accession>
    <name>A0A5C6ZMW8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carboxypeptidase-like regulatory domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05985</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022920910" evidence="1">
        <location>
            <begin position="20"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="270" mass="30647" checksum="4168207B13F78BC5" modified="2019-11-13" version="1">MKLKLLLSIFLMTSMVAISQTVGRVQINGKIIVEDSDVEGITIFNTSSNKGEATDENGKFKIKAKLNDNLEVRALQYQNFDIKITQAMIDSRRIRVFLIEEINKLPEVLVLTSSLSGNLGTDVEKVKTFNPKLDALYFGIKKQDEYVFSDDYRSEVTNEAVHSQVPQMVNGLNIVNVVDQLLLPLFRSNAKAQEGVEMPPVPNAAIKYYMGSNFLVDNFGIPEHRVEEFIQYVEDENFDFNLLNYGNEMAFLEILNKKSKTFLNQASEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN57</accession>
    <name>A0A5C6ZN57_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Homoserine kinase</fullName>
            <shortName evidence="5">HK</shortName>
            <shortName evidence="5">HSK</shortName>
            <ecNumber evidence="5">2.7.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">thrB</name>
        <name evidence="8" type="ORF">ESY86_01485</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + L-homoserine = ADP + H(+) + O-phospho-L-homoserine</text>
            <dbReference type="Rhea" id="RHEA:13985"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57476"/>
            <dbReference type="ChEBI" id="CHEBI:57590"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.39"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 4/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the GHMP kinase family. Homoserine kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.39" evidence="5"/>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00064"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004413">
        <property type="term" value="F:homoserine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00384">
        <property type="entry name" value="Homoser_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000870">
        <property type="entry name" value="Homoserine_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000676">
        <property type="entry name" value="Homoser_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="SSF55060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00191">
        <property type="entry name" value="thrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0791">Threonine biosynthesis</keyword>
    <keyword evidence="5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP_kinases_N" evidence="6">
        <location>
            <begin position="78"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP_kinases_C" evidence="7">
        <location>
            <begin position="205"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD91342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="304" mass="32641" checksum="550E7D64733FBA3F" modified="2019-11-13" version="1">MKIFSPATVANVSCGFDVLGFCLESIGDEMVIRKTDEKGIRITKIEGFDLPFEAEKNVAGVSALALMEAAKPNCGFEIEIYKNIKPGSGVGSSSASAVGSVFGINELLGRPFDKTQLTNFAMKGEALASQCEHADNIAPAIFGGFTLVKSVTPLEVLQLPTPANLFAVIIHPQIEIKTSEARSILPKQIDLQKAITQWSNVGSLVHALHTSDYGLLSRSLSDVVVEPYRKQLIPHFDDLRESALKNGALGCGISGSGPSVFSLCHGRETAKNVARAIKTLFSKTDIPFEMYLSRINTEGIKVIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN85</accession>
    <name>A0A5C6ZN85_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NAD-dependent succinate-semialdehyde dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_01625</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004030">
        <property type="term" value="F:aldehyde dehydrogenase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07100">
        <property type="entry name" value="ALDH_SSADH1_GabD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044148">
        <property type="entry name" value="ALDH_GabD1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="4">
        <location>
            <begin position="3"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD91309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="452" mass="49720" checksum="9D9A07721C39FFC1" modified="2019-11-13" version="1">MQFQSVNPYNNEPVGKFTALTKDELDEKLNKSQNAFESWKKVPIAERCQLIRNAAQVLRDHVDQYAKMITLEMGKPISESRAEVNKCAWVCDYYADNAETFLAHESIATDASQSFVRHDPIGAVLAIMPWNFPFWQVFRYAAPTLIAGNTGLLKHAPNVFGSAQLIEEVFTKAGVPDGVFQNLIVHHDQTEKIIAHDAVQAVTLTGSEKAGAAVAEIAGKYIKKTVLELGGNNAFIVWEDADIDKAVKIAVTARMLNCGQSCIAAKRFILMEAIYDEFVTKFTKAVSELKSGNPLENTTQVGPLARRDLADQLNRQVKESINQGAKLLLGGHQKDCYHEPTILGNVTAGMPAFDEETFGPLAAMIKARDIADAFALSEASKYGLGVTVCTKNVEKALKYADEVSDAAYFINELVKSDPRLPFGGSKKSGYGRELAKDGIMEFVNRKTVYVKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN94</accession>
    <name>A0A5C6ZN94_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Formate/nitrite transporter family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_00420</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000292">
        <property type="entry name" value="For/NO2_transpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30520">
        <property type="entry name" value="PTHR30520"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01226">
        <property type="entry name" value="Form_Nir_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="49"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="128"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="175"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="208"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="248"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD91095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="282" mass="31235" checksum="96B6F362AF812A49" modified="2019-11-13" version="1">MKGEEKNQEEHQKDLEKKSNQVEESKVYTEILSRIIHEGEEIFKLKRKAVFLSACIAGLEIGFSYVLVCTLYYLLAGSIDESIIYKLFGFVYPLGFILVVLGKSALFTEQTSVLALPVLNGQRSILDLLQIWGIVIFGNVIGGILFVFFIGAMASELGLFEKETMVTIGTHILDHSYLTLLLSAIAAGWLMGLLTWLLNSTLEALTRILIITIITGTIGFVGFHHSIVGNIEVFGAFLYSEDISILDYLLFLLITLLGNGLGGAIVVGLFKYRIFESNHAKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNB6</accession>
    <name>A0A5C6ZNB6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phage tail protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_00530</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011747">
        <property type="entry name" value="CHP02241"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010667">
        <property type="entry name" value="Phage_T4_Gp19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38009">
        <property type="entry name" value="PTHR38009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06841">
        <property type="entry name" value="Phage_T4_gp19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02241">
        <property type="entry name" value="TIGR02241"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="143" mass="16517" checksum="719375BEB169F784" modified="2019-11-13" version="1">MKDFPLPNFHFRVDWGGTSIGFQEVSGLKKELEILEYREGSSPEYFKRKMPGMHTLSDISLKRGVFLNDDEFYKWYNTVALNTVEKRDIVISLLNEEHEPTLVWNVKECFITSIEFSSLNAEENGNAIDTMVLANHGFTVKYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNG4</accession>
    <name>A0A5C6ZNG4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">50S ribosomal protein L9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rplI</name>
        <name evidence="10" type="ORF">ESY86_00095</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Binds to the 23S rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the bacterial ribosomal protein bL9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.430.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.5.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00503">
        <property type="entry name" value="Ribosomal_L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000244">
        <property type="entry name" value="Ribosomal_L9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009027">
        <property type="entry name" value="Ribosomal_L9/RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020594">
        <property type="entry name" value="Ribosomal_L9_bac/chp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020069">
        <property type="entry name" value="Ribosomal_L9_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036791">
        <property type="entry name" value="Ribosomal_L9_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020070">
        <property type="entry name" value="Ribosomal_L9_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036935">
        <property type="entry name" value="Ribosomal_L9_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21368">
        <property type="entry name" value="PTHR21368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03948">
        <property type="entry name" value="Ribosomal_L9_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01281">
        <property type="entry name" value="Ribosomal_L9_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55653">
        <property type="entry name" value="SSF55653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55658">
        <property type="entry name" value="SSF55658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00158">
        <property type="entry name" value="L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 7" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="RIBOSOMAL_L9" evidence="8">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L9_C" evidence="9">
        <location>
            <begin position="63"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD91037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="153" mass="16801" checksum="71889705C9E9649A" modified="2019-11-13" version="1">MELILKQDVENLGFKDDVVTVKNGYGRNFLIPQGQAIMATISAKKVLAETLKQREYKEKTVIAEAQKTADALKQLDIKITSKAGTGATAGDKLFGSITNMDLSHALKQQGHEVDKKFISINGGNIKRLGQYEAVIRLHRAVTVDMIFEVIADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNY8</accession>
    <name>A0A5C6ZNY8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">DUF421 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_00280</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UPF0702 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.240.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007353">
        <property type="entry name" value="DUF421"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023090">
        <property type="entry name" value="UPF0702_alpha/beta_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04239">
        <property type="entry name" value="DUF421"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="44"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD91071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="169" mass="18602" checksum="F6BEA2D580B18177" modified="2019-11-13" version="1">MNDWFTYSAESLIAIILTALGIYLALVIYTRISGKRSFSKLSSFDFAITVAIGSIMATSILSKSVSLVQGAVGLGILYLIQMLVAHLRRYQAVRKLLDNKPTFLMKDGVVLEANLKKCKVTLSDVKAKLREANVIQVSEIKAVVFESTGDISVLHGAEDKSIDDWLIDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZP60</accession>
    <name>A0A5C6ZP60_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ketol-acid reductoisomerase (NADP(+))</fullName>
            <shortName evidence="7">KARI</shortName>
            <ecNumber evidence="7">1.1.1.86</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Acetohydroxy-acid isomeroreductase</fullName>
            <shortName evidence="7">AHIR</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Alpha-keto-beta-hydroxylacyl reductoisomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 11" type="primary">ilvC</name>
        <name evidence="11" type="ORF">ESY86_02275</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(2R)-2,3-dihydroxy-3-methylbutanoate + NADP(+) = (2S)-2-acetolactate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:22068"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:49072"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58476"/>
            <dbReference type="EC" id="1.1.1.86"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(2R,3R)-2,3-dihydroxy-3-methylpentanoate + NADP(+) = (S)-2-ethyl-2-hydroxy-3-oxobutanoate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:13493"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:49256"/>
            <dbReference type="ChEBI" id="CHEBI:49258"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.86"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="7">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 2/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 2/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7 8">Belongs to the ketol-acid reductoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.86" evidence="7"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00056"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004455">
        <property type="term" value="F:ketol-acid reductoisomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00435">
        <property type="entry name" value="IlvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013023">
        <property type="entry name" value="KARI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000506">
        <property type="entry name" value="KARI_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013116">
        <property type="entry name" value="KARI_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21371">
        <property type="entry name" value="PTHR21371"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01450">
        <property type="entry name" value="IlvC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07991">
        <property type="entry name" value="IlvN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00465">
        <property type="entry name" value="ilvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51851">
        <property type="entry name" value="KARI_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51850">
        <property type="entry name" value="KARI_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 7 8" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0521">NADP</keyword>
    <keyword evidence="7 8 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KARI N-terminal Rossmann" evidence="9">
        <location>
            <begin position="14"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="KARI C-terminal knotted" evidence="10">
        <location>
            <begin position="209"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="KARI C-terminal knotted" evidence="10">
        <location>
            <begin position="345"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="132"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="45"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="108"/>
            <end position="110"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <position position="217"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <position position="389"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <position position="393"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <position position="414"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD90806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="502" mass="55420" checksum="9F06CE11338D73EA" modified="2019-11-13" version="1">MSNYFNTLSLRQQLEQLGKCRFMDASEFEDGVTALKGKKIVIVGCGAQGLNQGLNMRDSGLDISYALRQAAIDEKRESYKNASSNGFTVGNYDDLIPTADLVLNLTPDKQHSNVVKTVMPLMKKGATLSYSHGFNIVEEGTKIREDLTVIMVAPKCPGTEVREEYKRGFGVPTLIAVHPENDPENKGWNQAKAYAVATGGDKAGVLQSSFIAEVKSDLMGEQTMLCGLLQTGAILSFDKMVAEGIDSNYAAKLIQYGWETITEALKHGGITNMMDRLSNPAKLKAFQLSEELKDIMRPLFEKHMDDIISGHFSKTMMEDWANDDVNLLKWRAETGETAFEKTKLTSEHISEQDYFDHGTLLVAFVKSGVELAYETMVSAGIVEDSAYYESLHELPLIANTIARKKLFEMNRVISDTAEYGCYLFDHACKPLLADFMKSVDTSVIGKSYSNSNSVDNIELIAANDAIRNHSIEKVGKRLRAAMTAMKVIKSDEVDAEASVLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPC9</accession>
    <name>A0A5C6ZPC9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Amidohydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_02590</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022664823" evidence="2">
        <location>
            <begin position="19"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydro-rel" evidence="3">
        <location>
            <begin position="74"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD90866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="428" mass="45912" checksum="9D6C6CF3DEA03DB2" modified="2019-11-13" version="1">MKKSLQILILLLSVSVTGQSTYLHCGKLIDTKTGKVLTEKTIIVSDGRITSVENGYVQPKSEQDEVVDLKMKTAMPGLIDLHVHIESETNPKAYLETYTLNEADKAFKAAHYAIVTLMSGFTTVRDLGGTGVNVALRNAIAAGTVDGPRIFTAEKALATTGGHADPTNGSKRVLMGDPGPKEGVVNGVDDARKAVRQRYKNGADLIKITATGGVLSMAKSGQNPQFTLEEIKAICETAKDYGFHVAAHAHGDEGMQRAIKGGVKTIEHGTLMSDETMELMKQYDVYLVPTITAGKSVSEKAKIPGYYPEVIVPKALDIGPKIQDTFGSAYKKGVGIAFGTDAAVFTHGENGKEFGYMVEAGMPAMETIQSATITNAMLLKMEQELGQIKEGFIADIVAVNEDPTQNISTMENVVFVMKAGKIHKNAIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZQA5</accession>
    <name>A0A5C6ZQA5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00470</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="213"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="425" mass="49105" checksum="678D22DA21948BEF" modified="2019-11-13" version="1">MPFKNLKQHIIHQVTSGKQGKAFDFSNTFSEVLNRKIKHEEAIVLLTAMAPHIQPGFFEEIIQILHPDGGEFPQWGGVKHTNYRGFLPTGETVQYILAGKNINKRGLVQKYFSEDHWFFSTQTVLLENVQEGVPKMSGQLIMPAETIDLLLFGEVSLPAFGSQFPAELVATKMAWVDLVLSKETFEQIHQIRLWLKHEKKLRHEYGLDKRLSPGYRALFHGSSGTGKTLTASLLGKEFNMPVYRIDLSQIVSKYIGETEKNLERIFTRAENKNWILFFDEADALFGKRTATKDSHDRYANQGVSYLLQRTENFNGLILLASNFKENIDEAFIRRLNQIIEFPKPEFEDRLALWQKTIPKQLKAKTEILEKIAKEYELTGAQIVNAVSFVCLHFLEHKSKKVEHIQFMEAIKREFKKEERMFTQLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZQC8</accession>
    <name>A0A5C6ZQC8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="219" mass="24963" checksum="F98C1E9D5CB3B286" modified="2019-11-13" version="1">MKLKITLIVFCLCVCTCQKDNKATLEYTYATDTSILDCGTTNTKLFEEALLSFENDIVAFYKPFNGQVGNAYKQFITATTNRRATYNDIISDHSKAVFEALKTDKSLWKEGQQGKAYNYSHPIFSCISEHITDEKLGTTYRALLSTNSMSPRMLEYEIQRRVFSLSTDKFFATHVALDLFYGKLHEVDFTKPKADLSGEIIDRKNNPKTEKDPHAGHNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6Z9J4</accession>
    <name>A0A5C6Z9J4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_20775</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000126">
        <property type="protein sequence ID" value="TXD85818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009241">
        <property type="entry name" value="HigB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05973">
        <property type="entry name" value="Gp49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD85818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="112" mass="13252" checksum="228D140D4B595748" modified="2019-11-13" version="1">MRDIDITEECLEFIDKQNDRVSLKFFQLIEIIGEIKIVNSNFLKKLQSTQFYELRFKSGNEYRIVIFAIDHLNFAECTKAVCLCGFQKKGTKDYKKAIKQAEKILEDYLKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZA02</accession>
    <name>A0A5C6ZA02_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_20615</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000094">
        <property type="protein sequence ID" value="TXD86092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="107" mass="12600" checksum="43915EB13E150145" modified="2019-11-13" version="1">MEQKRRLRIKPTLFFPFVENALKHGSLNDKESFINITLKETEDRQLSYCLVNSTEHQDDNRFKLKNSGQFGLQALQDLLDAYYPNSNIEHRTLPNKQYLSKLTLNLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZA26</accession>
    <name>A0A5C6ZA26_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20585</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000090">
        <property type="protein sequence ID" value="TXD86123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007069">
        <property type="entry name" value="Transposase_32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026889">
        <property type="entry name" value="Zn_Tnp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04986">
        <property type="entry name" value="Y2_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14319">
        <property type="entry name" value="Zn_Tnp_IS91"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Zn_Tnp_IS91" evidence="1">
        <location>
            <begin position="22"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="261" mass="30027" checksum="A39E62C6B35159C4" modified="2019-11-13" version="1" fragment="single">MRPRHTVADVLEMEQLQLKSLGLTSWHCRALQAIRRCRTKAMGGHIDKCDCCHALHISYNSCRNRHCPTCQGHKREEWIRAREGELLNVPYFHLVFTLPSEFNSYALSHGKIVYGSLFRAAWQTLRQFGDNPKHLGGRMGMIAVLHTWGQNMSLHPHLHCIVPGGGLNRSGQWKKAKSNGKYLFNVKSMSKVFRGKYVAELRKSGLKIPQEVYSAVFGKKWVVFAKQPFGSPRYVIEYLGRYTHKIAISNHRITDVDRKNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZA43</accession>
    <name>A0A5C6ZA43_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">IS1182 family transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_19690</name>
        <name evidence="3" type="ORF">ESY86_19990</name>
        <name evidence="2" type="ORF">ESY86_20255</name>
        <name evidence="1" type="ORF">ESY86_20345</name>
    </gene>
    <organism evidence="1 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000066">
        <property type="protein sequence ID" value="TXD86382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="VORO01000062">
        <property type="protein sequence ID" value="TXD86416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="VORO01000053">
        <property type="protein sequence ID" value="TXD86533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="VORO01000046">
        <property type="protein sequence ID" value="TXD86619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD86619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="52" mass="6198" checksum="5AE2E58BFBCD312C" modified="2019-11-13" version="1" fragment="single">MKYISGKDRRQTCLFPVSLEDSIDQFNSVRAIDQFVEQLDLEKLGFRRDFIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZA51</accession>
    <name>A0A5C6ZA51_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19445</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000040">
        <property type="protein sequence ID" value="TXD86748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05483">
        <property type="entry name" value="retropepsin_like_bacteria"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034122">
        <property type="entry name" value="Retropepsin-like_bacterial"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="SSF50630"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="177" mass="19585" checksum="0932764C682A3BFB" modified="2019-11-13" version="1">MKFRLLTYIILSFALTSCNGCSKSAQKFRNNEVDNTSSKRERIVRERSTGKTIIKMEKRNGVYYVPIELNGAKMDFIFDTGAGIISISETEATFLMKQGTLTKDDIKGTAKFSDANGDISEGTIINLKTVKIGNITLRDIEASVVHNSVAPLLLGQSAFEQFGKISIDYKKGEITLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZA72</accession>
    <name>A0A5C6ZA72_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type II toxin-antitoxin system RelE/ParE family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19210</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000038">
        <property type="protein sequence ID" value="TXD86785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="96" mass="11622" checksum="0743DACDD1D3D6F0" modified="2019-11-13" version="1">MYELYISDETVLDIAEAIFFFNNIQEGVGYRFKEDLKKEIAFLRKHPEIIQKRHHDLRISFLKKFPFGIHFLLDENAVRVIAIFHTSRDPKRWKIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAI5</accession>
    <name>A0A5C6ZAI5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Antitoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_20140</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Antitoxin component of a type II toxin-antitoxin (TA) system.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the phD/YefM antitoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000058">
        <property type="protein sequence ID" value="TXD86459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006442">
        <property type="entry name" value="Antitoxin_Phd/YefM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036165">
        <property type="entry name" value="YefM-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02604">
        <property type="entry name" value="PhdYeFM_antitox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143120">
        <property type="entry name" value="SSF143120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009981"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="84" mass="9627" checksum="5DF6EF860504312E" modified="2019-11-13" version="1">MQIATVSDFRKDIKSYLDRVSKNFETLIINRGKDSGIVVMSLQEYNSLMATNHELSSRKNELRLDSAIDKLKSGMTFNKDLIEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZB53</accession>
    <name>A0A5C6ZB53_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_20155</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000058">
        <property type="protein sequence ID" value="TXD86462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="69" mass="7798" checksum="8127360837127C38" modified="2019-11-13" version="1">MYKQWLVLAYLEIPAEFPMASTCLQLSVTNHATAHTLNVVKNGGIHSELDNRNSKNYSFHGRGIFISDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZB72</accession>
    <name>A0A5C6ZB72_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FtsX-like permease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000044">
        <property type="protein sequence ID" value="TXD86652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="123" mass="13765" checksum="3A760B8BA4C1D624" modified="2019-11-13" version="1">MVTFRNPLAQLQLPRQVNATTNMQAALTSYELKGLFNFTGVGVLIIGWIAVAILIISVFSIFMSLYRVVWDRHYELALMSVYGASRVQLLCCVFYEGFLLSILGYALGGFFEQSGALHFQGRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBI0</accession>
    <name>A0A5C6ZBI0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_18695</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000033">
        <property type="protein sequence ID" value="TXD86957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="77" mass="8604" checksum="C2A3E66D0BEE38BF" modified="2019-11-13" version="1">MALINELAFLLTIQSTWGALDLVENASNEIQKQKSIKVYQEKVPASAENGLGNAHFPKHNFIICLRAETLELFIFAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC05</accession>
    <name>A0A5C6ZC05_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_05345</name>
        <name evidence="3" type="ORF">ESY86_19900</name>
    </gene>
    <organism evidence="3 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000051">
        <property type="protein sequence ID" value="TXD86572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_026813281.1">
        <property type="nucleotide sequence ID" value="NZ_VORO01000051.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033477006" evidence="2">
        <location>
            <begin position="21"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD90168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="95" mass="10197" checksum="4FA83329BFAF1774" modified="2019-11-13" version="1">MKKSLYLASFLSLLSTSLFAQIGGIEDSVNDVGDTIRTIFPILLGVIFLVGFLFNAGHFFGENADLKKGITRVLVFVLIAGAVVGIFTYLIGIVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC78</accession>
    <name>A0A5C6ZC78_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pyridoxine/pyridoxamine 5'-phosphate oxidase</fullName>
            <ecNumber evidence="5">1.4.3.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">PNP/PMP oxidase</fullName>
            <shortName evidence="5">PNPOx</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Pyridoxal 5'-phosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 11" type="primary">pdxH</name>
        <name evidence="11" type="ORF">ESY86_17130</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>H2O + O2 + pyridoxamine 5'-phosphate = H2O2 + NH4(+) + pyridoxal 5'-phosphate</text>
            <dbReference type="Rhea" id="RHEA:15817"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:58451"/>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
            <dbReference type="EC" id="1.4.3.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>O2 + pyridoxine 5'-phosphate = H2O2 + pyridoxal 5'-phosphate</text>
            <dbReference type="Rhea" id="RHEA:15149"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:58589"/>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
            <dbReference type="EC" id="1.4.3.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5 7">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="5 7">Binds 1 FMN per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor metabolism; pyridoxal 5'-phosphate salvage; pyridoxal 5'-phosphate from pyridoxine 5'-phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the pyridoxamine 5'-phosphate oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.3.5" evidence="5"/>
    <dbReference type="EMBL" id="VORO01000025">
        <property type="protein sequence ID" value="TXD87392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA01068">
        <property type="reaction ID" value="UER00304"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004733">
        <property type="term" value="F:pyridoxamine-phosphate oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008615">
        <property type="term" value="P:pyridoxine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01629">
        <property type="entry name" value="PdxH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000659">
        <property type="entry name" value="Pyridox_Oxase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019740">
        <property type="entry name" value="Pyridox_Oxase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011576">
        <property type="entry name" value="Pyridox_Oxase_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019576">
        <property type="entry name" value="Pyridoxamine_oxidase_dimer_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10851">
        <property type="entry name" value="PTHR10851"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10590">
        <property type="entry name" value="PNP_phzG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01243">
        <property type="entry name" value="Putative_PNPOx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000190">
        <property type="entry name" value="Pyd_amn-ph_oxd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00558">
        <property type="entry name" value="pdxH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01064">
        <property type="entry name" value="PYRIDOX_OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 5 7" id="KW-0288">FMN</keyword>
    <keyword evidence="4 5 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0664">Pyridoxine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Putative_PNPOx" evidence="9">
        <location>
            <begin position="40"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="PNP_phzG_C" evidence="10">
        <location>
            <begin position="174"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="9"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5 6">
        <location>
            <begin position="193"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="142"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <begin position="63"/>
            <end position="68"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <begin position="78"/>
            <end position="79"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <begin position="142"/>
            <end position="143"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000190-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000190-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF10590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD87392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="215" mass="25352" checksum="8DCBB4BF016655AF" modified="2019-11-13" version="1">MKSDLGNYRKSYEKEQLLEKNVGYNPFDLFKKWFEEVETNFDVGEVNAMTLSTIGLDGFPKSRVVLLKEFSAEGFTFYTNYESEKGRGIMINSNVCLSFFWETAQRQVIIKGRADKIEESQSDAYFQSRPRGSQLGALVSHQSKVIESRKLLEDRLHNLENEYEDKVIERPDFWGGIIVKPVEIEFWQGRPNRLHDRLRYKLDSEYNWKRERLSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCD0</accession>
    <name>A0A5C6ZCD0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_16860</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000024">
        <property type="protein sequence ID" value="TXD87449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027791">
        <property type="entry name" value="Galactosyl_T_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02709">
        <property type="entry name" value="Glyco_transf_7C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="12"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_transf_7C" evidence="3">
        <location>
            <begin position="143"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD87449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="360" mass="42420" checksum="51B8C4FD277A977A" modified="2019-11-13" version="1">MSKALSVLYIYRNKDLHRVENSLNSLCQQSNNDFEIIFVDYGSTRNYKDGLSEFLKQYKNVKLIYSYHTDQPWSRPKAVNIGVKHCKSDYIFVADIDMIFRHDFISILHRIKHPNKSFFFKVGFLSEAESKKNIPFREYAISFESKYGAQGLSLFPRHALNEVNGLSEFIHFWGADNDVHNRLRNTGMETIFYDDKILILHQWHLIYRKTLEKFLTVEIQLSNVLRINMQHQINNDKGEISKVNVNPWGNIITKKQFDLLASAPVQRELVNIKSVVDYFLFYELPLHQTGVLSIQFYEDPFQKTLKYHAKKMLGKTVPLYYCLKEINDKLLLHIISFYNHFPYSYKVSGDLKTITFSILK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCF7</accession>
    <name>A0A5C6ZCF7_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Lipoate--protein ligase</fullName>
            <ecNumber evidence="4">6.3.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_19140</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(R)-lipoate + ATP + L-lysyl-[lipoyl-carrier protein] = (R)-N(6)-lipoyl-L-lysyl-[lipoyl-carrier protein] + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:49288"/>
            <dbReference type="Rhea" id="RHEA-COMP:10500"/>
            <dbReference type="Rhea" id="RHEA-COMP:10502"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.1.20"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein lipoylation via exogenous pathway; protein N(6)-(lipoyl)lysine from lipoate: step 1/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein lipoylation via exogenous pathway; protein N(6)-(lipoyl)lysine from lipoate: step 2/2.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.1.20" evidence="4"/>
    <dbReference type="EMBL" id="VORO01000037">
        <property type="protein sequence ID" value="TXD86809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00537">
        <property type="reaction ID" value="UER00594"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016979">
        <property type="term" value="F:lipoate-protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019491">
        <property type="entry name" value="Lipoate_protein_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004562">
        <property type="entry name" value="LipoylTrfase_LipoateP_Ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12561">
        <property type="entry name" value="PTHR12561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03099">
        <property type="entry name" value="BPL_LplA_LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10437">
        <property type="entry name" value="Lip_prot_lig_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00545">
        <property type="entry name" value="lipoyltrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="8">
        <location>
            <begin position="27"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD86809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="338" mass="38889" checksum="61CF728260E39417" modified="2019-11-13" version="1">MIFIENEGHTNPRLNLALEEYILRNLNPTNDYLLFYINEPSIIIGRNQNTLEEINQRYVEDNNIHVVRRISGGGAVYHDFGNLNFSFITNHDGKSLNNFKKFTAPVIKVLQSLGLNAELKGRNDIQVEEKKISGTAQFSTGKRMVSHGTLLLDTNLGEVAKALNVKMGKIESKGHKSVRSRVANISEYLDQPLKIEAFRQLVLEGLYEEREPFERYELTAVEWQSVKQLKEDKYDTWDWNYGRSPKFNIQRSKRFSIGELDLRIFVEKGHIQDLKIFGDFFGKEPLESLETLLVGTRYDKDAISSRLKATAIEDYFGDLPKNEFIDLVYGDNEVNAEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCM3</accession>
    <name>A0A5C6ZCM3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_16715</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000023">
        <property type="protein sequence ID" value="TXD87535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="220"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="262"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="165"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="288" mass="33333" checksum="8954ADB86053369B" modified="2019-11-13" version="1">MFRKLFILVLSLFILSCGDGLTYEQKINDYNLYISKADSLIQINNYEEAIKYANTAIAITDTLSVGFIKKGEACYALDWLDFAEENFDEAIEIEGKSSKVYKLRALVHLKNNDSDFLDDINVYIERHPDDDEALELRRDYYEQENKLDEAVEEYSNAITKDSDNVDLYIKRSELYFQNGNYEDALKDYNTILAFVPDNKPVEIKKTNLESLMSDNQNRNVFLILLIGIYILYLPLSFYVFKPLAARKAQNQIGGNFTMLKDPLVWALPIFLSIVFLTLYITDSVPNFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-02-10" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCN1</accession>
    <name>A0A5C6ZCN1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha-ketoglutarate-dependent dioxygenase AlkB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19335</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000039">
        <property type="protein sequence ID" value="TXD86775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006307">
        <property type="term" value="P:DNA dealkylation involved in DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035552">
        <property type="term" value="P:oxidative single-stranded DNA demethylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.590">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027450">
        <property type="entry name" value="AlkB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037151">
        <property type="entry name" value="AlkB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032854">
        <property type="entry name" value="ALKBH3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31212">
        <property type="entry name" value="PTHR31212"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13532">
        <property type="entry name" value="2OG-FeII_Oxy_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="1">
        <location>
            <begin position="101"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="200" mass="23210" checksum="122EC6CD7A017450" modified="2019-11-13" version="1">MDLFSEEKTLLQLPNAELLYLPHFFSKTEADAYFEILKATIAWQQDDIKVFGKIHAQPRLTALYAENETPYSYSNITMQPKPFTAELLAIKTKIEQEIQHRFSTVLLNLYRDGADSNGWHADNEKELGKNPVIASLSFGAVRPFHFKHRQIKAQRHKLDLEHGSLLVMRGEMQQYWLHQIAKTKKPIGSRINLTFRSLKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCU5</accession>
    <name>A0A5C6ZCU5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Vancomycin high temperature exclusion protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18965</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000035">
        <property type="protein sequence ID" value="TXD86893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06259">
        <property type="entry name" value="YdcF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003848">
        <property type="entry name" value="DUF218"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02698">
        <property type="entry name" value="DUF218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF218" evidence="1">
        <location>
            <begin position="47"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="209" mass="23431" checksum="AA2B868813E1282D" modified="2019-11-13" version="1">MKKLKLLLLAVVFVLLGVITTNYWVAFKASGHVYDDLDLIPTNKVGMVLGTSKYVSGGNINLFYTYRIEATVKLYQAGKIEFVLISGDNGSKYYDEPNTFKKDLIEKGIPEAKIFLDFAGFRTLDSVVRVKAVFGQDEVTIISQKFHNQRAIYLAQNYNIKAVGFNARDVSGKGGLKVQLREYLARAKASIDILFDVEPKFLGENVEIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCV6</accession>
    <name>A0A5C6ZCV6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">YtxH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000034">
        <property type="protein sequence ID" value="TXD86933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="91" mass="10446" checksum="53797BBC1561F3D1" modified="2019-11-13" version="1">MAIIAHITLIGWIIALVMNNEKKSEFASFYIRQVLGIMLLGFVCSFIPIIGWFAWIFVLVLWVMSLISALNGQKKPILLLGEQFQDWFKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCV9</accession>
    <name>A0A5C6ZCV9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Corrinoid adenosyltransferase</fullName>
            <ecNumber evidence="4">2.5.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Cob(II)alamin adenosyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Cob(II)yrinic acid a,c-diamide adenosyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Cobinamide/cobalamin adenosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_16975</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>2 ATP + 2 cob(II)alamin + reduced [electron-transfer flavoprotein] = 2 adenosylcob(III)alamin + 3 H(+) + oxidized [electron-transfer flavoprotein] + 2 triphosphate</text>
            <dbReference type="Rhea" id="RHEA:28671"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
            <dbReference type="ChEBI" id="CHEBI:18036"/>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="EC" id="2.5.1.17"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>2 ATP + 2 cob(II)yrinate a,c diamide + reduced [electron-transfer flavoprotein] = 2 adenosylcob(III)yrinate a,c-diamide + 3 H(+) + oxidized [electron-transfer flavoprotein] + 2 triphosphate</text>
            <dbReference type="Rhea" id="RHEA:11528"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18036"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:58503"/>
            <dbReference type="ChEBI" id="CHEBI:58537"/>
            <dbReference type="EC" id="2.5.1.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 2/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the Cob(I)alamin adenosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.17" evidence="4"/>
    <dbReference type="EMBL" id="VORO01000024">
        <property type="protein sequence ID" value="TXD87471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00148">
        <property type="reaction ID" value="UER00233"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008817">
        <property type="term" value="F:cob(I)yrinic acid a,c-diamide adenosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016030">
        <property type="entry name" value="CblAdoTrfase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036451">
        <property type="entry name" value="CblAdoTrfase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029499">
        <property type="entry name" value="PduO-typ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12213">
        <property type="entry name" value="PTHR12213"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01923">
        <property type="entry name" value="Cob_adeno_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89028">
        <property type="entry name" value="SSF89028"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00636">
        <property type="entry name" value="PduO_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cob_adeno_trans" evidence="5">
        <location>
            <begin position="3"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU366026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD87471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="191" mass="21653" checksum="BD5E6FCFA46C9405" modified="2019-11-13" version="1">MKIYTKTGDKGTTALFGGTRVPKHHIRIDSYGTVDELNSHLGLIRDQDMDQHYKDIIMKIQDRLFTIGSTLATDPKKALLKNGKERLNIPKISEADINILENEIDAMNDALPPMTHFVLPGGHQTVSFCHIARCVCRRAERLASALNDLEPFQPESLTYLNRLSDYLFVLARKLSHDLEADEVQWIPQKNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-02-10" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD06</accession>
    <name>A0A5C6ZD06_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Deoxyguanosinetriphosphate triphosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18365</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000031">
        <property type="protein sequence ID" value="TXD87024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008832">
        <property type="term" value="F:dGTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006203">
        <property type="term" value="P:dGTP catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023293">
        <property type="entry name" value="dGTP_triP_hydro_central_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027432">
        <property type="entry name" value="dGTP_triphosphohydrolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006261">
        <property type="entry name" value="dNTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020779">
        <property type="entry name" value="dNTPase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11373:SF32">
        <property type="entry name" value="PTHR11373:SF32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01353">
        <property type="entry name" value="dGTP_triPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="1">
        <location>
            <begin position="64"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="447" mass="51017" checksum="26CED3E6C1C6E9F0" modified="2019-11-13" version="1">MNWEQLLSLKRFGDKNKRLRKEQDETRLGFEVDYDRIIFSSEFRGLQDKTQVVPLSKTDFVHTRLTHSLEVSVVGRSLGRKVGQRLLEKHPHLRDAHGYQINDFGAIVAAAALAHDIGNPPFGHSGEKAIGQFFKSGDGRYFEDQLSEKEYQDLCDFEGNANGFKMLCESRAGRPGGLRLSYAVLGAFTKYPKESLPKKPTNHVADKKYGFFQSEKAEFQDLAEELGLLKRGHQDDISYARHPLAYLVEAADDICYTIIDFEDGINLGLIQEEFALEYLLNLVRHTIQTSTYNQLQSTQDRLTYLRALAINTLINEAVELFMEHEEAILNGEFPKSLMDCSQYEAQIKDIIKVSIENIYQSREVVNKELVGYKIINELLKVFTEAVINDHKNQSSHFDRLVLKVLEKQINLNQETTYELLLAVCFCISKMSDSNAILTFKKLNAAEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD81</accession>
    <name>A0A5C6ZD81_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">PorV/PorQ family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_16750</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000024">
        <property type="protein sequence ID" value="TXD87474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="346" mass="38382" checksum="459A7A0B2437EAEF" modified="2019-11-13" version="1">MISLLSTAQTTRKYSNEFLNIGVDAAALGMSNAVSSHTSDVNAGYWNPAGLVNLEDNQLALFHSSYFANIANYNYIAFAKPLDDKSAVGFSLIRFGVDDILDTTQLIDDQGNINYDRVSLFSTADYALTFSYARRLPLDGFSYGVNAKVVRRIIGDFASSWGFGLDAGIQFQSKNDWKFGIMARDITTTFNAWSFDDEKLADIQNAVEGQNQTVPESTELTLPKLQIGLSKKFVFHYDYSLLTSFDLNVRFAETNDIISTSVASINPALGFEFGYTDLVFLRAGAGNFQNELQLDNTESLSFQPSLGLGFKYRGIQIDYAFTDIGDQSAALYSNVFSLKLDFSIFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDA6</accession>
    <name>A0A5C6ZDA6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-acetylneuraminate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_16850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000024">
        <property type="protein sequence ID" value="TXD87447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016051">
        <property type="term" value="P:carbohydrate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006190">
        <property type="entry name" value="AFP_Neu5c_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036732">
        <property type="entry name" value="AFP_Neu5c_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013132">
        <property type="entry name" value="Neu5Ac_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03102">
        <property type="entry name" value="NeuB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51269">
        <property type="entry name" value="SSF51269"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50844">
        <property type="entry name" value="AFP_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AFP-like" evidence="1">
        <location>
            <begin position="279"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="336" mass="37242" checksum="78A7EC464571F30A" modified="2019-11-13" version="1">MIKKFPFIIAEIAQAHDGSLGMAHAYIDALAATGVDAVKFQTHIAEAESSVYEPFRIKFSRQDFTRFDYWKRMEFSLAQWKAIKTHCDAVGLEFMSSPFSNAAVDLLEQVGVKRYKVGSGEVTNFLLLEKIAQTKKPVILSSGMSCFEELDAAVSFLKDRNVPVSILQCTTSYPTGPEQYGFNVVQELKERYKVPVGYSDHSAKIETCIAASALGAEILEFHVVFDKAMFGPDVSSSLTLTETKQLVAAVKNIKLAMSHPIDKNNNSSFEDLKLIFEKSLSVNKTLPKGHLLQFEDLEAKKPANKGISASDFKSVIGKSLNCDKAQWEFLNIGDIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDA8</accession>
    <name>A0A5C6ZDA8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type IX secretion system membrane protein PorP/SprF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_18105</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000029">
        <property type="protein sequence ID" value="TXD87140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019861">
        <property type="entry name" value="PorP/SprF_Bacteroidetes"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11751">
        <property type="entry name" value="PorP_SprF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03519">
        <property type="entry name" value="T9SS_PorP_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="324" mass="37071" checksum="4B3B8B170964545B" modified="2019-11-13" version="1">MKNITRYIVFLFVVMNGYSQELNLPVFTQYLADNDFVISPTYAGIGDNFRIRANGLTQWVGIKDAPDNQSLYVDFRIADRSGVGISLYNDKNGNTLQKGVKLSYAHHLILDYRSRQYLSFGISYNLNSFRIDINNFEGTFEQPIVDPSITDDRSTSNNNFDFGMLYRNKGFFLSANANNLLEKDIDNFTGIEPNLLLNFQIYSGIKIKSASNNLVEFEPSVFYQLFSSDGRSSTDVNFKYKKYNTQGDYYWAGVSYRFLNDQFMKPLNIGPMAGIMKSKFYFAYSYQLTTNDLMGYNSGTHMITIGLDFLQGMSNCPCTTTLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDB3</accession>
    <name>A0A5C6ZDB3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000051">
        <property type="protein sequence ID" value="TXD86575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="221"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="250" mass="29406" checksum="BD6938160881D9C1" modified="2019-11-13" version="1">MNYIKLLNSAFEKFYFDDRLNPTHISLYMALFQEWNSSRFADELYVNRRDLMRCAKIGSKSTYHRCITDLDAWLYLSYFPSNNPYKGSKIKMAIIETSVEPVVGRYNPTLEQLAEHYHPIREPVVGQHHPINGQVVNQHRPIGGQALVSTINNNKQENNIKQPKGWQAVFIFFEEKGFDADEAKKFFEHYQTRNWQTSDGNDIRDWRAVATNWMDRTELFDEENKSNKKQASQIKDNLRTTKNKDYGQPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDC1</accession>
    <name>A0A5C6ZDC1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF1501 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_18165</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000030">
        <property type="protein sequence ID" value="TXD87058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010869">
        <property type="entry name" value="DUF1501"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07394">
        <property type="entry name" value="DUF1501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="396" mass="44344" checksum="27E58B183E5C2D82" modified="2019-11-13" version="1">MNRRHFIKQSSLASSLIFVPNFMRAFEQISPQHLGYKRLVMIQLSGGNDGLNTIVPFNDDAYYNSRPKIAIAKTDVLKMTDDLGFHSSLLPLKRLYDDGNLSVINNVGYPNPNRSHFRSTAIWQTASAADEYLQTGWIGRYLDAYGTSPHNAIEIDDSLSLALKGETNNGIATKNPNVLFRTSNDPYFKNILAHQNDTHLSEHNLGYLYKTMIDAQSSAKYIFEKNKTATNAVEYPQNAFANQLKTAARLINSGMETRVFYTSLGGFDTHANQVNSQKRLLSMYAEGIEAMVKDLKSQGSFNDTLIVTFSEFGRRVKQNAANGTDHGAASNVFIIGNQLKQQGFYNDLASLSDLDPNGDLKYTVDFRAIYATVLNKWLEVGKQNIINPSFENLNFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDD4</accession>
    <name>A0A5C6ZDD4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">T9SS type B sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_16685</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000023">
        <property type="protein sequence ID" value="TXD87530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026341">
        <property type="entry name" value="Bac_Flav_CTERM"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04131">
        <property type="entry name" value="Bac_Flav_CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1580" mass="171816" checksum="65F13C2696646BF2" modified="2019-11-13" version="1">MTDLVQNSLGQGCVEISNVSSAVNGSSTGIDSYGQFQQVNSNFPFVDGLILSTGSIASAANTFNATTLSEGDASWQTDSDLETVLGLSNTLNATSIEFDFISANNTVEFNYILASEEYFGTNPCNESDAFVILIKEVGSTGPYTNLALVPGTTLPTNSQNIRQEIFGFCEAQNPEFFEGYSIGDTNFNGRTTVLTATANINRNVSYHIKFAIADKQDSFFDSAVFIQGSSFEASVDLGEDITTCAESLTIDGSFPNNAAIYSWFKDGTLIPGETNPNLTVTESGTYSVAINIPFLSSSCSITDAVEIVLNAEQSAGVISDFIKCDDPSGDGVEVFDLSTKTDEALAAVPDSNYTISYHASAADASNNINPLPDNYTSLSNPQTIYVAIKDVFSGCLAFSTFDLVLISPPVVSAPTPIVVCDKDAPDGRTRIDLDDSTAEILGSNPNFTLTYHNSYVRALSGSNPINSPYNTRPFNDVLYIRVTDSETGCSAVTTLDITILEKPTLDSSITHYINACLSDGSQFADFNLNSVTAAVLDGLTGVDVSFHELETEAETGANPITNSSNYQNTNANFQTVYMRVVDNTIGCPSVEPIELHTNIFNTGLNLNTAFECDDASLDGIVDFDLTEVEADIVGDLEGFNLIFYESQSDQDSNSNAIDTSVPYTISTAPQAIYVSVSNGSCSGEVVLDLGINPPIEIQAFGTVDYCDNDQDGITNISLPSFNAIVNVGISSPSVRYYLTETDALNDENNLGNNFTNTANPQLLYVRVTNNATSCFDVAPLTIDIHPAPVTSEPSPIIICDNDQDGFFTVNLSSKISEIVSSTANLEIKFYESQINAENEEAPILSPSSYNASTQTIYTRVTIGATGCFSVVELPIFINTTPVFGDIADFENCEPDGSVVSEFFFNLKDEDVLDGQTGKDVLYFESEQDAIDRVNAIDKFSAYTSISIPQTIYVRVESITDVTCFGTSEFDLAIGFLPNFNEPTDLFICDDISNDGITSIDLNDKLIEITSGITDDLNIAFYESKADAINQVNQLPLNYTTSNNPQQVFARIDEGESCFSLVDILVNVIPVPSLNPSYELVQCDVDYDGLVNWDITSVVTQITEVRFSDVDITYHLSLEGAETDTQIIPTATDFDNTVNPQTIYLKVNNILSNCAAIVPVALIANGPPALSAIDTVEICSNDEGSTQLSSFNQQLLEQTANVLVSYYASESDAINQINVLDDTYFYASNNDTLFARVQFSTTQCLFIKEFNLKVNPTPIASPPMDLEACDDDYDGLLAFDLNQQNASILGSANPSDFFIYYYNDLVFAQEGFDPITYVSYAASNNETLYARLEHKFTGCYDITSFTVFVNPLPVVNIDDQILCLETSPLLVSANTNIPGDSYLWSTTATTPEIEISSIGNYSVTVTSALGCATTRSFEVTESEIASIEFTEVINFDDPNNVTVTVTGSGDYLYQLDNLPPQQFNVFQNVPLGYHTITIIDQNGCGEVSREIVVMDTPKFMTPNGDTYFDTWHITGVENLPGTIINIYDRYGKLLKQLSAFSRGWDGTYNGQAMPASDYWYVAKVRQGDQVFELKGHFTLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDE9</accession>
    <name>A0A5C6ZDE9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Efflux RND transporter permease subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19215</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000038">
        <property type="protein sequence ID" value="TXD86800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="348"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="374"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="401"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="445"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="476"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="516"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="540"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="591"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="952"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="979"/>
            <end position="998"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1004"/>
            <end position="1027"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1069"/>
            <end position="1095"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1115"/>
            <end position="1142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1177" mass="130960" checksum="2F5255A00444C7F6" modified="2019-11-13" version="1">MKKKKNTEKEFAWASWAINNKTTMYVLIAMFFYLGITAFFSMPRENFPEVNETKIYVSSIYPGNTAEDIEKLITDPLEDKLKTVSNVVEITSTSQEDFSMLVVEFDEHVSVEQAKQKVKDEIDSETSGEDWPTFNDAKVEPDVFELSLSEEMPILNINISGDYTVEKLKDYAEYLQDEIEDLQEIKKADIRGAQEKEVEIAVDIFKMMAAKVTFNDIISAINNGNVTMSAGNLVASGQRRTIRILGEIDSPSELENFVVKAENANPIYLKDVASVSFQEEDKTTFARKSGKPVVMLDVKKRAGKNMVAAAEQIQDIVSDAVANEFPPDLEVSITNDKSSVTIGQVDDLVNNIIFGVILVVTVLMFFLGFKNALFVGFAIPMSMFMSLMVLNLIGYSLNTMVLFGLIMGLGMLVDNGIVVVENVYRLMEDEGMSRIEAAKKGIGEIAFPIIISTATTVAAFIPLGLWPGIMGEFMKILPITLSIVLGSSLFVAIFFNSVLVSRYMTIEDKDMPLSQIIKITSIVAVIGLLILLFGGAYRGLGTIMIFTAIMLWAYRFFIRNWANNFQNKSLVKLENWYEVRLRNALSKKRPYILSIGTFLLLIAAFVAFGISLNAQRTKVEFFPDNKPNQIIVYIEYPQGTDINKTNAITKQIESRVYDVINQDQYMDGDRNFMVESAVSQVGEGAGNPRNDAGSAAEMPHKAKITASMREYKYRRGEDSELLRQKVQQALAGIYPGVLISVEKDANGPPAGSPINIELDGNNYNDLIATAEQMREFINSRNIAGIDELKIDVNKDKPTMQVEVDREKAGELGISASQVGQQLRNSIFGAKAGIYKEAGDDYDIYVRFNEANRYNTSALFNQNITFRDNTGVIKEVPLSAVAKQKNNSGFSAIKHKATKRVVTVYSALAPGFTDAGAIVTQIQNEMKSFKGLSEEIHIDYTGQIEEQNKQMTFLMGAFFIGLGLIFFILIFQFNSISKPAIIMIAIFLSFIGVFGGIVISGSAFVIMMTMVGIISLAGIVVNNGVVLLDYAQLLIDRRKNELNMEEEEFLETEDLFESIVKAGKARLRPVLLTAITTILGLIPLAIGLNINFFTLFADFDPNIYMGGDNVVFWGPLAWTVIYGLLVATFLTLIVVPILFFLSVKLKMWGRLKFTSTPLRHSEESEIDEIGARQVALDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDK5</accession>
    <name>A0A5C6ZDK5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HATPase_c_4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000028">
        <property type="protein sequence ID" value="TXD87163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025831">
        <property type="entry name" value="RecG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038475">
        <property type="entry name" value="RecG_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13749">
        <property type="entry name" value="HATPase_c_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HATPase_c_4" evidence="1">
        <location>
            <begin position="14"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="184" mass="20733" checksum="CE015536E6A4726C" modified="2019-11-13" version="1">MNLKFVFELLGLANIFTDRIEITSAGGLPEGLSKQEFFEGFSIPRNKELMRIFKDLELVKQLGSGIPRILEHYGKEGFSFSDNFLRMTLIAKEVTDEPTVKADDKEGGHITDLVIDAIAELTHRQKEILKLTNAKSRISRSGIGEVILSNESAIQKHLNNLKEAGFLKRKGGTRGYWQINLENK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDX0</accession>
    <name>A0A5C6ZDX0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_15845</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="65" mass="7942" checksum="D5FBE546EA3E7494" modified="2019-11-13" version="1">MIYLNFTDLSEEAQNRILENSKKDVERQFGDSIRKYVKENYTCFETMIQEEALRNLYSYKYIFNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDX1</accession>
    <name>A0A5C6ZDX1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DUF86 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_14270</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the HepT RNase toxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110001">
        <property type="term" value="C:toxin-antitoxin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008201">
        <property type="entry name" value="HepT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037038">
        <property type="entry name" value="HepT-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01934">
        <property type="entry name" value="DUF86"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD88114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="130" mass="15150" checksum="5656ED447E718C96" modified="2019-11-13" version="1">MLESAEKIQRYTANLNPSRGFYSPRLASKSKEHLSIHTRGLAPRLLIFDEFLKQEMVRDAVARNFEIIGEASNRISADFKTSNPHVEWTRMTGLRHRIIHDYFGIDHEIMWTIIQDNITPLIDDIKDLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDZ6</accession>
    <name>A0A5C6ZDZ6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CHAT domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_15640</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="828"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="domain" description="CHAT" evidence="2">
        <location>
            <begin position="570"/>
            <end position="817"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="854" mass="98633" checksum="94B1E16D5535A5E5" modified="2019-11-13" version="1">MLWIIDDLGYVSKTLYDFETSLNYYSKSMPLYEKYHPEKLADVGTNYNMMATGYKKLGLRKKEYTILKEAEFIWDNNSIEGYYVSKFTCYEQLAVWNIYYGNFNEAEVYLRKQEGLLPNLIDNFKVTERTYLSRNFRLRIYYNYIELYFKSEDYKKAENYLQLFKNQLPKNNLKPPLEPHFLSLYYSYLARLPNSSADEGIAHLKKAIEIIETYDGKIQLDATAIKRQLFQLQLQTKDYVAAEQSIDHLLKTSKNTNHNLQFFLLNTKANLLAQKGDHNQAENAFKKSISFLVAETDKPLQLETLGIAQLKPFYSFETVNGLILASKFYNKKHNTTQRGLALKISKNLVLLASKVFDNLYLGDRYNDNLYDSYKNIEQQTLSILSVNTDENDIKIHLEALENNATKFTWSKFMYSKTRPNLNIPDRIVNKETELKSLINYYQNELYKNKDERLNLDTLKTRLSESNVALHKLQAHIKKDYASYYNSNYNTFNLSEFQNELGTDQTVLKYSISEEKLYCFIISKSTIGFQSITQPKNFEKHIENYIIALKTFNSDIETNLNALQPIVPKGILENPKTKITIVPDGVLCYLPFETLDGTTEFLNSSVSFSYASSLSLLKDQYSFFNTSEAIKLAYFSAQYDEANQLPSAINEKINILNSLDGKSFYNLTSEALIEKAKQYDVLHFAMHSTINKENPDFSNFNLGNETLLMSNLYHESFKAQLAVLSACETGSGDFENGEGIQSASRAFTYTGIPSIVMSLWKVDDAATAKIMSAFYSNLKAGQTKDLALKNAKISYLETVEEEALKHPYYWAGFIISGNTTALINTDYSLYWYWGIGLCLLVILFYRKKWKTNPRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE51</accession>
    <name>A0A5C6ZE51_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF4974 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_13425</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006860">
        <property type="entry name" value="FecR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032508">
        <property type="entry name" value="FecR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012373">
        <property type="entry name" value="Ferrdict_sens_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30273">
        <property type="entry name" value="PTHR30273"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16344">
        <property type="entry name" value="DUF4974"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04773">
        <property type="entry name" value="FecR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018266">
        <property type="entry name" value="FecR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="FecR" evidence="2">
        <location>
            <begin position="153"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4974" evidence="3">
        <location>
            <begin position="292"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="369" mass="41543" checksum="38F42CFD7CD9D33A" modified="2019-11-13" version="1">MKLISLLLKSDMTQKNKNPFNSEPLSTKDKLHLRHRIFSSIYHYKRKKRVFRFGVGASVAVVLLLVTFSVLRGSGANASGIEHFVASQKDIPAGQEIQLILNDQHKVNVSEENAKISYSTTGKEVRIGDSKALNQNANPSEAIVYNTLLVPYGKRSEITLSDGSKVWLNSGSKLVFPAKFAAEKREVYLEGEAIFEVSHNENKPFHVQSKNHDLQVLGTVFNLSNYKDDAAIYTVLKSGSVQINYKTNALFNTQKSVKIKPGMLSAFNKNDREVQKSQVDVERYFSWRDGVFIFKNDALKSIMKKLSRYYNVEISIADDALANETFSGYLDVKDNIESVMETIKAAETPGFTYERTADHKLIISLKQNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE52</accession>
    <name>A0A5C6ZE52_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">2Fe-2S iron-sulfur cluster binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_14045</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140647">
        <property type="term" value="P:P450-containing electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001055">
        <property type="entry name" value="Adrenodoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23426">
        <property type="entry name" value="PTHR23426"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="2">
        <location>
            <begin position="42"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="111" mass="12443" checksum="892F2E8BA9D87493" modified="2019-11-13" version="1">MEEQDINITIIDREGIKHQIQAPTDMAMNLMEVVRSYELAPEGSIGICGGMAMCASCQCYVRSNHELPEMQDEEEAMLSEAFYVKDNSRLGCQIRITKDLEGLEVELAPES</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEA2</accession>
    <name>A0A5C6ZEA2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleotidyltransferase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_13300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025877">
        <property type="entry name" value="MobA-like_NTP_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12804">
        <property type="entry name" value="NTP_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transf_3" evidence="1">
        <location>
            <begin position="10"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="201" mass="22555" checksum="D645417A284E7A2E" modified="2019-11-13" version="1">MIKNAKIGVMILAAGSSSRLGYAKQLVEFKGKSLLQHAIAISEVMDFDSKVLVLGARKEEIERKIDLKGFEILINENWEEGMASSIRKGVLRSQELENNLDHIVILLSDQPFVSRESIEALIQVQLDKNSQATFSEYAGDIGVPAIFSAEVFHDLKELKGDQGAKKLIHDQKLDFEIVKFEMGNFDVDTSEDVELLKQMEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZED9</accession>
    <name>A0A5C6ZED9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Noncanonical pyrimidine nucleotidase, YjjG family</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_14765</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008253">
        <property type="term" value="F:5'-nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011951">
        <property type="entry name" value="HAD-SF_hydro_IA_YjjG/PynA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02254">
        <property type="entry name" value="YjjG/YfnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="229" mass="26736" checksum="1FA21BC7D722197F" modified="2019-11-13" version="1">MKLKGIKHIFFDLDHTLWDFDKNSSLTFQKIFGLHNVDINHEHFVKAYEPINLNYWKLYREEKINKENLRYQRLKDTFDVLNVFVEDALIDKLSSDYVVHLSSFTHLFEGTFELLDYLKPNYELHIITNGFDEAQHKKMNNSKIAPYFKTMTNAEIAGVKKPDPIIFNYALELAKASPGESIMIGDNYEADILGAKALGLEVILFNYHNSVVEANIKQVKLLQELRQYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEE7</accession>
    <name>A0A5C6ZEE7_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosomal RNA small subunit methyltransferase G</fullName>
            <ecNumber evidence="2">2.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">16S rRNA 7-methylguanosine methyltransferase</fullName>
            <shortName evidence="2">16S rRNA m7G methyltransferase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 3" type="primary">rsmG</name>
        <name evidence="3" type="ORF">ESY86_16560</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Specifically methylates the N7 position of a guanine in 16S rRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000023">
        <property type="protein sequence ID" value="TXD87506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070043">
        <property type="term" value="F:rRNA (guanine-N7-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00074">
        <property type="entry name" value="16SrRNA_methyltr_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003682">
        <property type="entry name" value="rRNA_ssu_MeTfrase_G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31760">
        <property type="entry name" value="PTHR31760"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02527">
        <property type="entry name" value="GidB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003078">
        <property type="entry name" value="GidB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00138">
        <property type="entry name" value="rsmG_gidB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="2">
        <location>
            <begin position="122"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="209" mass="23913" checksum="94FA7F52762E87FC" modified="2019-11-13" version="1">MELIQRYFPNLSEQQIKQFQDLDRLYQDWNLKINVVSRKDIEELYLRHVLHSLGIAKVITFKPGSKILDVGTGGGFPGIPLAILFPDSRFHLVDSIGKKLKVVDEVVAGLDLKNVKTTNSRVEEVDDQFDFIVSRAVAAMPTFVHWVKGKIAKKQNHELKNGILYLKGGDLSEELATYQTATIYELSDYFEEAFFETKKVVHLPIKFRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEW4</accession>
    <name>A0A5C6ZEW4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17695</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000027">
        <property type="protein sequence ID" value="TXD87268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022952626" evidence="1">
        <location>
            <begin position="21"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="192" mass="21316" checksum="71238E560814ADC3" modified="2019-11-13" version="1">MKPITFILMLALLFSCSEDATEAIDDLQESDVLMLKVDFTTHAFEGGTQIVVAEPSSDFDITSSYQAPGDFGGIQLYSANSNTLLFDGTIIWMGLGLMEYPASIKPASSFETLEEALPLPSAEAFSKVMYDEYAYYPEDMNLATIWSAIDKLAVVKDFRQSNPEAKIQLFLYTPSVGIGDPADWDWMLFLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEX8</accession>
    <name>A0A5C6ZEX8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PNPLA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_15830</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="1 2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="3">
        <location>
            <begin position="11"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="2">
        <location>
            <begin position="73"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="2">
        <location>
            <begin position="313"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD87780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="599" mass="69262" checksum="8D0DA9AA7FD66EFA" modified="2019-11-13" version="1">MGKENTFHLGITMAGAVSAGAYTAGFIDYLIEALELWEEQKLIITNKIFKNETLTNYEKKIPLHNVCIDVLGGASAGGMVGMITALSTYSKMPPVKKPTNDKTGNILYDSWVLLDDDIDVSLKNNVTTFQKMLYTDDFEVNPDGIPSLLNSKSIDRIADKVFNELVSLEKKRERPNYISEDLRVLVTLCSLRGIPFELNFERITSANFPYSPGHRMNEHMIIAHFKIKYDEKLDKDVYLKFDPYDKDSEELLKLCTKATGAFPIGLAPRHFEGKLSTEYIKNCILRNLEIKDEDKSAINIKLDDEYFDFTDIDGGTINNEPYSEVVQVLEEVSPNHDRKFPMFGTIMIDPFPNFYDQDEFKPKKNPLKDLVFQKSFWSVIPEAYFTFREQVRVKHSGSFYKDYFRLLIFPVKWEQNGVLKNHPPIACGALGGFGGFLDIEFRKHDFFLGRNNARNFLRGFFMLEYNEEKLHPLFSGLNQEAVDTFRRKIKNAEESETIYFPIIPDLNFISDKKGGHTNPYHYTIDEFPKLKPGYFDSIKPNLKNRVNKILTYEINKRFEKKWLLRNALKVVKGYVSKRIVNSVIKIMEKDFASRNMMPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEZ5</accession>
    <name>A0A5C6ZEZ5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA polymerase sigma factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_17370</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000026">
        <property type="protein sequence ID" value="TXD87330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="12"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="3">
        <location>
            <begin position="108"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD87330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="164" mass="19493" checksum="9AA961A10C9E86E0" modified="2019-11-13" version="1">MDKALEHQFVALLEKHQNIVHKVCRLYTNNQDAHNDLFQEITIQLWKAYPKFRGEAKFSTWMYRVGLNTAITLYRKSKRTIKTQEFETVSFKIKAEPYDDTQDQQLKLLYQAVYQLNDIEKALVFLYLEEKNYSEISETLGITEVNARVKMNRVKKKLRTVLNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF24</accession>
    <name>A0A5C6ZF24_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Succinylglutamate desuccinylase/aspartoacylase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_13815</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007036">
        <property type="entry name" value="Aste_AspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043795">
        <property type="entry name" value="N-alpha-Ac-DABA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04952">
        <property type="entry name" value="AstE_AspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039012">
        <property type="entry name" value="ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD88171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="336" mass="36693" checksum="F84D323FA507CDDB" modified="2019-11-13" version="1">MGKKEAKLEDALDILGVKVAKGSSATLSFNVAKLHTQNRIDVPIIIARSRKPGPTVLITAGIHGDEINGVEIVRQIIAKGINKPKIGTIICIPVINVFGFIHMDREFPDGRDLNRVFPGIQGGSLASRVAFQLVTEILPHADLVMDFHTGGAGRFNASQVRIVQDDPKLEELANVFGAPFILYSNNLSKSFRNTCQKLGIPILLFEGGKSFNIDNSITNTGVNGAKRVLNHLGMLGAKFKVSAPKNPCIKIKESKWVRAKFSGMFKSSVLINSYVEKGDVLGNITDPYGSFNHFVKAPNAGYVFNINESPIIYQGDAIFHLSLDVNNDQIRITENL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFB7</accession>
    <name>A0A5C6ZFB7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_13225</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="61" mass="6846" checksum="F4F4F029189075BE" modified="2019-11-13" version="1">MNSIVNVNVERTILFEIATSEPTTLIVLMLNRTNKVTILPLYSNSFRSTQNVLTVFNTGIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFK4</accession>
    <name>A0A5C6ZFK4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Alanine:cation symporter family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_16210</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015655">
        <property type="term" value="F:alanine:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001463">
        <property type="entry name" value="Na/Ala_symport"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30330">
        <property type="entry name" value="PTHR30330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01235">
        <property type="entry name" value="Na_Ala_symp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00175">
        <property type="entry name" value="NAALASMPORT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00835">
        <property type="entry name" value="agcS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0769">Symport</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="140"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="303"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="343"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="373"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="402"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="456"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="511"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="554"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="578"/>
            <end position="597"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD87580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="626" mass="67431" checksum="876858AFB7EFD1D6" modified="2019-11-13" version="1">MKKYLLSIFIAILPILIFSQETDLQKDELSTSQKIDATFKNYTGWFVDGIFAEIPFGEISEEISLDLTKEDPVKYIKTVENDTVHITGIRLPSNRIATLITIESGNDLTIRDENSLVIPISDMSSNPSVTLMAQAPYASIPWVLIVLIGGALFFTIYFKFINVTGFTTAFAVVRGKYEDIEKHGVDTLYGDQTENEGENIIETIRDDSADGEVSHFQALTAALSATVGLGNIAGVAVALSIGGPGATFWMIVAGLLGMASKFAECTLGVKYRDVGEDGTVYGGPMYYLTKGLKTKGMGGFGKVLAFLFAIFVIGGSFGGGNMFQANQAAAQFVKLFELEGSNAGLYFGLVMAGLVAVVIIGGIKRIAKVTEKVVPFMAGIYVLASLIILGANWHLIDDAFVLIYQGAFSGLGIAGGLIGVMIQGIRRGAFSNEAGVGSAAIAHSAVRTKYPASEGIVALLEPFIDTVVICTMTALVIVITNFDGQFMQYGVEITEGVEITAQAFDTVIPHFSIILTIAVILFAFSTMISWSYYGMQGWVYLFGKGKITDLVYKVLFLFFVVVGASISLGAVINFSDAMIFAMVVPNIIGVVLLSPVIKKELKKYYKAIETKREAIDDGATDFTDKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFK6</accession>
    <name>A0A5C6ZFK6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase M14</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11795</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M14" evidence="1">
        <location>
            <begin position="35"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="378" mass="42563" checksum="84E6198F2B28D352" modified="2019-11-13" version="1">MNISEQKSLFERYKEPSIFGRYLNNSSLKTWRDKLSPKIRLNHLGVSVEHRVIISLTIGSGSTKIFLWSQMHGNESTTTKSVIDLLNVLSAENEFAAKILSRCTIKVIPILNPDGAEAYARVNANTIDLNRDAQALSQPESRILRDVFDRFKPDYCFNLHDQRSIFGAGACNASATVSFLSPAEDAEISLTPNRKKAMTLIAQMNANLQQQIPGQVGVYDDAYNANCVGDTFQALAPTILFEAGQFKQDYQREITRQFIFQSLLVAMEHIATPEVSTNDFSSYLDIPRNEKCFYDVIIRNTKQQDIAIQYEERLVGQSVDFVPKVVKIGPLNSEFAHLELQANNQQVLSEKKEVLKVGSEIVCVMMNNEKIALKPKFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFQ2</accession>
    <name>A0A5C6ZFQ2_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Elongation factor 4</fullName>
            <shortName evidence="5">EF-4</shortName>
            <ecNumber evidence="5">3.6.5.n1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Ribosomal back-translocase LepA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">lepA</name>
        <name evidence="7" type="ORF">ESY86_12945</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>GTP + H2O = GDP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.n1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
            <orientation evidence="5">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.n1" evidence="5"/>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045727">
        <property type="term" value="P:positive regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03709">
        <property type="entry name" value="lepA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00071">
        <property type="entry name" value="LepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006297">
        <property type="entry name" value="EF-4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038363">
        <property type="entry name" value="LepA_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013842">
        <property type="entry name" value="LepA_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035654">
        <property type="entry name" value="LepA_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43512">
        <property type="entry name" value="PTHR43512"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06421">
        <property type="entry name" value="LepA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01393">
        <property type="entry name" value="lepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="6">
        <location>
            <begin position="2"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="14"/>
            <end position="19"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="130"/>
            <end position="133"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD88420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="598" mass="66909" checksum="020F670AEFECF01B" modified="2019-11-13" version="1">MKHIRNFCIIAHIDHGKSTLADRLLDFTGTVTEREKQDQLLDSMDLERERGITIKSHAIQMEYVHEGVNYTLNLIDTPGHVDFSYEVSRSIAACEGALLIVDAAQSIQAQTISNLYLALENDLEIIPVLNKVDLPSANPEEVTDDIVDLLGCNPEDVIHASGKTGFGVDLILKAIIDRIPPPKGNIDEPLQALIFDSVYNPFRGVETYFRVINGVIKKNQLIKFIATGNTYGADEVGTLKLKQFPRNEIRAGDVGYVITGIKEAKEVKVGDTITDAKNPTQNPISGFEDVKPMVFAGIYPVDTEDYEDLRSSMEKLQLNDASLVFLPESSAALGFGFRCGFLGMLHMEIIQERLEREFDMTVITTVPNVSYHAFTHKNPEEIVIVNNPTDLPDPSTLNRVEEPYIKATIITKADFVGNVMSLCIEKRGVITNQTYLTTERVELTFDMPLAEIVFDFYDRLKTVSKGYASFDYSPIGLRASKLVRVDILLNAQPVDALSALIHFDNAYHIGKKMCEKLKELIPRQQFDIPIQAAIGAKIISRETIKALRKDVTAKCYGGDISRKRKLLEKQKKGKKRMRQVGNVEIPQEAFMAVLKLND</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFR8</accession>
    <name>A0A5C6ZFR8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PKD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_16030</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000021">
        <property type="protein sequence ID" value="TXD87665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022409">
        <property type="entry name" value="PKD/Chitinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000601">
        <property type="entry name" value="PKD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035986">
        <property type="entry name" value="PKD_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00089">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49299">
        <property type="entry name" value="SSF49299"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50093">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022736753" evidence="1">
        <location>
            <begin position="25"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="domain" description="PKD" evidence="2">
        <location>
            <begin position="59"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="768" mass="82853" checksum="84575888BB77BD6C" modified="2019-11-13" version="1">MKNIIKGIKIVFMLSLAFSFSGCDDDDENLPKIEALFTHTINQEAGVVTFINASSNADSYSWDFGDGTASTENNPTKIYTSGVYTIVLTAKNVAGATDTFEDTITIQIPEDIALPITFDDPLVAYDATTFEGTSFAVVENPDASGANDLVSNVGAITNSGAVFEGLFFDLGLPLDLSTDKSVTMKFWSQIPINVLVKLEAGNGVDVETTASHGGSGWEDIYFTFDSAVSYSKFTMFVDGSGTTAGAFYMDDVEQLNSDDVPCLITELALPFDFDCESIDYSTKITGDVSFAVVDNPELSGINDQLTKVGQITNVGNQFENAFFNLDTPIDFATDKGVRFKLFSNQALPVLLKFEDGTDVDVEDTEMHGGTGWEELTFTLNSSASYNDMILFVDGAGNAVGTFYVDDFEQVFVNLGTPCTPEVSQSLNAADFNLTFLNDPTASITSDGAGFAWIDNPDFDNTVNTSCKVGQIDRTSAAQFANNQITLDAKLDFNTNSGFKLKVWSSTSETPVLLKLEDQNDAGIFKEVPVTTSAGSAMQWEELTFNFAAGDSNKYDKIVLFFALGTSTEAIYYIDDLALFSDGGGSTGGGGCDGDAVAATSLPVDFEDCESFISTFSSVESNPVLTSLVDNPASSGINTSDYVLRITKPSGINRWGGIQNSFPAGTIDFTTQTFKVKVYSSYSDVTYRFELALDPQTTPVTGNPAPQFRQVSGGANEWVEIEFTFINLPPSGSPTTYNQLVIKPDNPDGTDGDVTTEERVYYIDDLRLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFX9</accession>
    <name>A0A5C6ZFX9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">1,4-alpha-glucan branching enzyme</fullName>
            <ecNumber evidence="3">2.4.1.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_14525</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Transfers a segment of a (1-&gt;4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain.</text>
            <dbReference type="EC" id="2.4.1.18"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 13 family. GlgB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.18" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003844">
        <property type="term" value="F:1,4-alpha-glucan branching enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102752">
        <property type="term" value="F:1,4-alpha-glucan branching enzyme activity (using a glucosylated glycogenin as primer for glycogen synthesis)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043169">
        <property type="term" value="F:cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02855">
        <property type="entry name" value="E_set_GBE_prok_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006048">
        <property type="entry name" value="A-amylase/branching_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037439">
        <property type="entry name" value="Branching_enzy"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044143">
        <property type="entry name" value="GlgB_N_E_set_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004193">
        <property type="entry name" value="Glyco_hydro_13_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02806">
        <property type="entry name" value="Alpha-amylase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02922">
        <property type="entry name" value="CBM_48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000463">
        <property type="entry name" value="GlgB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aamy" evidence="6">
        <location>
            <begin position="125"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="5">
        <location>
            <position position="285"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000463-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD88097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="596" mass="67514" checksum="B48905A250AFF9B7" modified="2019-11-13" version="1">MAKKLSTAQGMGATVSDKTITFRVWAPNAKQVFVTGSFNDWDYKALKLKHEANGYWAIATHKARVGDEYKFVIINAESGNELLRNDPYAYQMTNSNGNSVIEDFHFDWEDEGFEIEDWNKLIIYELHVGTFHRSAKDKVGTFGNVIKKLPYLKKLGINVIELLPVAEFAGGISWGYNPAAPFSVENDYGGSEGLANLVNEAHKAGIAVILDVVYNHLGPSDVDLWQFDGWSNNDKGGIYFYNDHRSKTPWGDTRPDYGRPEVRQYFIDNALMWLDKFHLDGLRFDATAYIRYEEGGLGMGNAIDEGNLMIKEINREIMANHPKAITIAEDLKGDENVTKLFADGGLGYGSQWDSKFVHPVREVLEQPNDQDRDLQKIVDALCYSYNESAFQRVVYTESHDEVANGKARVPEEIQPGDANSEFALKRAILGIVLVMTAPGIPMIFQGQEFMVDKFFKDDEGLDWRQEKEHDTITQLFRQLCALRLGNFNSEGLTGQYMSVLHMNQDTKVLAYRRSQHEDFKNATLVVMNFSNTEYTDYEMGLSNADKSELLFNSVSKEYSPQFSELPVENLKIVNEAFDDQSHKAILNIPAYAALIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGB3</accession>
    <name>A0A5C6ZGB3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_13540</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="422" mass="47510" checksum="775B0809E8596789" modified="2019-11-13" version="1">MESTDWGHKPLRLNLNDNGTHWISFHTYAQFWMRGTENNPGSSLSEEPQSSTFDISIRRFRLGIQAQLTEQLFVYSQVGINNLNYLSPRGTPTDLLDAYAEYALSEALEFGAGKTAWTGLSRYSAPNTSKLLSHDIVLLALPTSDETNDLIRKLSVYAKGKLGALDYRIVYSKPFSPRNSANFDSELIENSAKFTDKSTGNIYSGYFKWAFLDSESNKIPFSDGTYLGKKKILNIGIGAEFQNMALASLQNGETQFHDMSLWAADVFLDLPINQKKTSVLTSYLGYFNYDFGPNYIRNTGVNNPIVSVNPDQASFNGAGNAYPVVGTGNSIYAQIGYLFPYLGATQKYGRLQPFVSYQYSDFEVLNDPMTTYDFGINWYLKGHLSKFTLNLQSRPIYGETSEGITLEDRKWSVILQYIIRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGG7</accession>
    <name>A0A5C6ZGG7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">4Fe-4S binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_09060</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12801">
        <property type="entry name" value="Fer4_5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13187">
        <property type="entry name" value="Fer4_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="93"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="179"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="299"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="332"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="363"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="397"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="444"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="475"/>
            <end position="504"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD89197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="530" mass="59476" checksum="2A5D2AE95660AB85" modified="2019-11-13" version="1">MNTPNPSMSLTKPEAFDLSTKQRIYVAMGMIGLIILALAAFNVTFPYRPLALTTALVLIALGAILFANDLYLGKMEGIKNDGVMFKSISSRGIWAWISGIAFTSFYILLYFRAEWLGLAKEGAENTGLVALFDPLSKLLNGNPASQWFVYGTLYTLAILVFGYKFLLKYRNNSYQRLRTFSVMFFQLSFAFLIPEFMSRLNSESFSLPYYDLKNIWPLNYYNFEQYRVDDFISAGNAGLALLIFGLLSIFVITPILTYKYGKRWYCSWVCGCGGLAETAGDSFRHLSDKRQFAWKIERWVVHSVVVFVTLMTTAVVYSYLGEDSSTYWLTKSTFLIGVGSLLTIVFALVMIFKREQLAKDAQYGAIGYFVIIMVLIGLHYFNGSDLFLFRAESLRQYYGFLIGAIFSGVIGTGFYPIFGNRVWCRFGCPMAAILGFQQRLFSKFRITTNGGQCISCGNCSTYCEMGIDVRAYAQKGENIVRSSCVGCGICAAVCPRGVLKLENDGLKGRINSNDILLGNDVNLMDLVNEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGL2</accession>
    <name>A0A5C6ZGL2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_09755</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="12"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="350" mass="39586" checksum="C37312CEED7ED568" modified="2019-11-13" version="1">MSSVNKDLPKTILVTGAAGFIGFHLCKALLERGHNVLGLDNINDYYDINLKYSRLEELGIDRLKAENFSEYTTSTIYGTQMTFVRMNLEDRMELPKIFKDFKISQVCNLAAQAGVRYSLENPEAYIDSNIVGFLNVLECCRNFKIKKLVYASSSSVYGNSEEVPFKETANVDHPISLYAATKKSNELMAHTYSHLYGFETIGLRFFTVYGPWGRPDMAMFLFTDAIMHDKPIKVFNNGELSRDFTFIDDIIAGVLATLLNSGKDQTKPMSKLYNIGNSQPVKLLDYVAAIENELNKKANKAMMPMQAGDVNQTFANIDALKADYKYQPKTSIKEGIASFVDWYNSYYNKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGN7</accession>
    <name>A0A5C6ZGN7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">SH3 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_13160</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003646">
        <property type="entry name" value="SH3-like_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08239">
        <property type="entry name" value="SH3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00287">
        <property type="entry name" value="SH3b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51781">
        <property type="entry name" value="SH3B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022688626" evidence="3">
        <location>
            <begin position="19"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="128"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="54"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="SH3b" evidence="4">
        <location>
            <begin position="187"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD88456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="252" mass="28514" checksum="153A56681D96A981" modified="2019-11-13" version="1">MKQFLIAMVLLLSALSFSQNDTLFEQANQLYSDANYTEALQKYKAIMDSGEQSAALYFNMANAHYKLNHIAPSIYYYEKASLLNPNDKDIKNNMAFAKNMTLDAIDTVPEVGLAKLMNSWTKTFYYEVWAKISVAFAILFVILFISYFFVSSTGKKRFAFVSSILCLLLVFASFGLAYHGHDLVANNQPAIVFAKEAQIKSEPNLRSTEAFKLHEGTKVQVLDSVDNWKKIKLADGKTGWVMNEDIKLVKTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGQ7</accession>
    <name>A0A5C6ZGQ7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12165</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="6"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="238" mass="27137" checksum="03854FAEF6ACEEFB" modified="2019-11-13" version="1">MDYTFTIIVPVYNEEDNLERVEQELLSYTKIATRITKILFVNDGSSDGSQSLIEAICKRQDHFSYILFAENRGLSAAIKAGFDYVDTELVGYIDSDLQTAPEDFNKLLEHVGDYDLVTGVRADRKDKFVKNMSSKIANNIRRAFTNDGMDDTGCPLKVIKTAYAKRIPMFKGLHRFLPAMILLQNGKVIQIPVQHFPRMAGTAKFGLWNRLFGPLMDCFAYLWMKKKYINYTVSKTSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGU0</accession>
    <name>A0A5C6ZGU0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_12390</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="60" mass="6807" checksum="191E3ADF503A8791" modified="2019-11-13" version="1">MKTTKKEKTTARPAGGFDAVKMMRDIRDNISAETQNMNFDELKAYMKAKIQDSKLKPVGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGU7</accession>
    <name>A0A5C6ZGU7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heavy-metal-associated domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08185</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="SSF55008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMA" evidence="1">
        <location>
            <begin position="53"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="138" mass="15139" checksum="92616CF2F5FD9DAE" modified="2019-11-13" version="1">MKSIKTLLVAVMTCTSILACKNEAQPEVKTVASSTGTETEVIQKLDPNATYAKAEFKIDGMTCAMGCAKTIEKKMAKMDGVKSAKVDFDRKLAMVEYDEAMVTPKTLEETVAKAGESYKVKEMHAVENFSTEEKPNKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHX6</accession>
    <name>A0A5C6ZHX6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_09695</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="384" mass="43016" checksum="AB4626711858A1A7" modified="2019-11-13" version="1">MNTDLSPKHIKSIDQSTILWFQCSNHFTIVSPANYELINRFLNAKTPAHFLRSLQEELGFEQAEAAELHKELEAFLKAANSNATTKIDRAIAEDINPPEQSIAIHYHFGNLGVQVNYGSEKIKGLFHPQLAHFSSNTSEAVGMILDIFQVDKLLYLFKNKTPAYAYDTISYHFIQGAFSLELTNYIHNKTASNWLASFHASTICNDQEAIMLVGESGNGKSTLSALLTAHGMDLLADDFTPMYADDLMLYRYPNAVSIKAGAFDMMAKTVRNFETLETHFKDAKQTNVKYLPSAVDYASAVKALPCKTIVYVKYSKDGDSNLKKASAEKILATLIPDSWISPQPEHAKLFLDWLEQVRFYELNYSDNDFAISAFKTLFDAAAAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHZ3</accession>
    <name>A0A5C6ZHZ3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11165</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="206" mass="23222" checksum="C74F71BC99652A21" modified="2019-11-13" version="1">MKTAGIIMIIGSLLLLGLFKFPLWNIMLGAPQYPDPLGMDIYITGIQGVDEFDLQNIDGLNHYIGMKTIPKPEEMWEFSVFPKVILGMAILGVIIGILGFFKKLNYKFFLGWFLLMTVLGVLGMYDFNNWLTDYGSNLDPNAIIKVTNPDGSPMSYKPPLIGYQKLLNFDVDSWPHIGGYLLFVGMILTLIAFWLGRRASLKKTTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHZ6</accession>
    <name>A0A5C6ZHZ6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_10650</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="12"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="136" mass="15543" checksum="F04AEACC46BA41E6" modified="2019-11-13" version="1">MKNNKFQNMKRELVIIDDDPIYRLIISKMVNTIDASVIIDECENCEMGLAKMESLGQLDHDVIVLLDINMPKLDGWGFLDEIEKSNILIQPQITIYMVSSSTDESDLLKSKKYKSLRGFFCKPLSKEVLKTIIGID</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI02</accession>
    <name>A0A5C6ZI02_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Formylglycine-generating enzyme family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11215</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005532">
        <property type="entry name" value="SUMF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042095">
        <property type="entry name" value="SUMF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03781">
        <property type="entry name" value="FGE-sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="SSF56436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FGE-sulfatase" evidence="1">
        <location>
            <begin position="43"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="259" mass="29803" checksum="20DA501CF2B85644" modified="2019-11-13" version="1">MKFQAISIVFVLLVFQTVLFAQSDGMVFIEGSRYLPLYGRDSTVVEVKDFLMDQYPVTNADYEKFVKDNPKWRKSKVIKLFADDSYLNNWKNDLELKHSERADSPVTFVSWFAAKAYCDCQDKRLPTVDEWEYVGMADETTKDARSKKAYNEQILAWYEAPRSNENSIGQTPKNAYGVYDLHGLVWEWTQDFNSVMITGESRKDKDLDNNLFCGSAAVNATDLMNYAAFMRYAVRGSLKAKYAMKNLGFRCVKDSAIDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI84</accession>
    <name>A0A5C6ZI84_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Thiamine_BP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_08525</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0045 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.930">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029756">
        <property type="entry name" value="MTH1187/YkoF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002767">
        <property type="entry name" value="Thiamine_BP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01910">
        <property type="entry name" value="Thiamine_BP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89957">
        <property type="entry name" value="SSF89957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thiamine_BP" evidence="2">
        <location>
            <begin position="5"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="86" mass="10039" checksum="EF5D1A089E944CE1" modified="2019-11-13" version="1">MNISVELTLTPLHDDYEPAIIHFIKKLRASKLKVLENPLSTQVYGDYDAVMQVLTVEIKEAFELIERGVLQMKIVKSDRYDYEPHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI89</accession>
    <name>A0A5C6ZI89_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GIY-YIG nuclease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12795</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035901">
        <property type="entry name" value="GIY-YIG_endonuc_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01541">
        <property type="entry name" value="GIY-YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82771">
        <property type="entry name" value="SSF82771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GIY-YIG" evidence="1">
        <location>
            <begin position="2"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="104" mass="12736" checksum="C4FC7F9CC5B873C2" modified="2019-11-13" version="1">MYFYYVYIIECSDKSYYTGITNDLDKRYKEHEFGKYKDCYTFKRRPLILKFQEPFNDVLQAIYFEKKLKGWTRVKKKALIEGDSDMLQILSECRNATHYKYYGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIA0</accession>
    <name>A0A5C6ZIA0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Deoxyribodipyrimidine photo-lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_06675</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the DNA photolyase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901363">
        <property type="term" value="F:heterocyclic compound binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097159">
        <property type="term" value="F:organic cyclic compound binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051716">
        <property type="term" value="P:cellular response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036134">
        <property type="entry name" value="Crypto/Photolyase_FAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036155">
        <property type="entry name" value="Crypto/Photolyase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005101">
        <property type="entry name" value="Cryptochr/Photolyase_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002081">
        <property type="entry name" value="Cryptochrome/DNA_photolyase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018394">
        <property type="entry name" value="DNA_photolyase_1_CS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006050">
        <property type="entry name" value="DNA_photolyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455">
        <property type="entry name" value="PTHR11455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00875">
        <property type="entry name" value="DNA_photolyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03441">
        <property type="entry name" value="FAD_binding_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00147">
        <property type="entry name" value="DNAPHOTLYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48173">
        <property type="entry name" value="SSF48173"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52425">
        <property type="entry name" value="SSF52425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00394">
        <property type="entry name" value="DNA_PHOTOLYASES_1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51645">
        <property type="entry name" value="PHR_CRY_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0157">Chromophore</keyword>
    <keyword evidence="3 5" id="KW-0274">FAD</keyword>
    <keyword evidence="2 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Photolyase/cryptochrome alpha/beta" evidence="6">
        <location>
            <begin position="4"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD89881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="435" mass="51804" checksum="E330369449CD2711" modified="2019-11-13" version="1">MKQPLNIFWFRRDLRLDDNLGFFEALKSDHPVLPIFIFDSEILDKLPKDDARLTFIFNTLQKMRSELQEKHDSSLAMYHGKPKAIFEQLLKDYEINTVFTNRDYEPYATERDETIEKLLLEADVKFNTFKDQVIFEKDEVVKKDGDPYVVYTPYMKVWKENFKGHDLKIYYTNEHLDNLVKNTRLPNLSLSDMGFESSKQAIADYEVTPTLIQNYEDTRNFPALDATSRLGPHLRFGTVSIRKMIKKAIAEKNEIFWQELIWREFFMQILWHFPRTADESFKTKYDRIEWRNNEAEFKLWCEGQTGYPLVDAAMRQLNETGFMHNRVRMLVGSFLCKHLLIDWRWGEAYFAEKLHDYEMSSNVGNWQWVAGSGVDAAPYFRIFNPSTQIDKFDKDRKFIKKYVPEFETANYPDKMVDHKEARERCLKVYKEAVSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIN7</accession>
    <name>A0A5C6ZIN7_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Endonuclease</fullName>
            <ecNumber evidence="6">3.1.30.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_12530</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the DNA/RNA non-specific endonuclease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.30.-" evidence="6"/>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.570.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018524">
        <property type="entry name" value="DNA/RNA_endonuclease_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001604">
        <property type="entry name" value="DNA/RNA_non-sp_Endonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044929">
        <property type="entry name" value="DNA/RNA_non-sp_Endonuclease_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020821">
        <property type="entry name" value="Extracellular_endonuc_su_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044925">
        <property type="entry name" value="His-Me_finger_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040255">
        <property type="entry name" value="Non-specific_endonuclease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13966">
        <property type="entry name" value="PTHR13966"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01223">
        <property type="entry name" value="Endonuclease_NS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00892">
        <property type="entry name" value="Endonuclease_NS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00477">
        <property type="entry name" value="NUC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54060">
        <property type="entry name" value="SSF54060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01070">
        <property type="entry name" value="NUCLEASE_NON_SPEC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 9" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease_NS" evidence="8">
        <location>
            <begin position="59"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="NUC" evidence="7">
        <location>
            <begin position="60"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU366055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD88559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="268" mass="30103" checksum="D86205A3AAE95C7C" modified="2019-11-13" version="1">MKRKTLYTIAAVLVLVGVFGYELVLNDDASAEVIQQGRTAKPKTNTYFLPTSTTGQIVYHDGYTLSYSEANEQAEWVAYELKRSDLSTTNFKRPYFEIDEAVETGAAHWRNYKNSGYDRGHLCPAADRKYSQQAHDETFLTSNVSPQLHNFNAGIWNSLEQKVRYWANTYNGVYVVTGGVLKGNLKSIGTEKVSVPNQFFKIVIDYNSGNPKMIAFLMPHENSNLPLYTFVVSVDSIETLTGIDFFPGLEDGIESSLEASSDHKAWSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIQ5</accession>
    <name>A0A5C6ZIQ5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_09950</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="124" mass="14597" checksum="99ED787E30BED310" modified="2019-11-13" version="1">MIHSDKEKYSDILSDSVTYLEQRGYENIKADMEGYETPKSYHKKGSDINITPDIVATKEGRKHYFDISLKSEEPKLLKSKWLFLNTLTSMRSQKFRLITTRGHYKFTNEMLDDINLTDKKLIKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIW5</accession>
    <name>A0A5C6ZIW5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sodium:proton antiporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_06420</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018461">
        <property type="entry name" value="Na/H_Antiport_NhaC-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03553">
        <property type="entry name" value="Na_H_antiporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="97"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="157"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="213"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="257"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="279"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="406"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="436"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="525"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="domain" description="Na_H_antiporter" evidence="7">
        <location>
            <begin position="182"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="domain" description="Na_H_antiporter" evidence="7">
        <location>
            <begin position="388"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD89833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="557" mass="59726" checksum="8BF21C33804AA8FF" modified="2019-11-13" version="1">MEDDKNSSEFEAGGQHIVENRELNLFEALIPVVILMGMLAYNIFFVEGQEWFGTYTNQIILLLGGGVAAVVGFFNKVRFKRMLKEIWENLQSVFVPIMILFLVGALAGTWLISGVIPAMVYYGLQVLSPAIFLPASVVIAAVISIATGSSWTTSATVGIALVGIGTALGINPGMIAGAVISGAYFGDKMSPLSDTTNLAPAMAGTDLFTHIKYMAFTTVPTILITLIVFGIISASLQTTGNADISQILETIAATFNITPWLFLVPIAVVGLILLKTKPLIALGTGVVLAGIFAFVFQPEVLENVTGSKTETIVKAVLTDTNIPIDDKSYTANLNEQDREAIANNADLAPLFKEGGIEKNFSDEELAKLFSETTYDQATLDEKVDSISKLLTIDKLKQLFGSGGMEGMIWTILLICCAMVFGGIMDAIGALARVTKALLSVASSIFGLFASTVASCIGLNIVASDQYLAIVIPGKMFKKAFEDRDLAPENLSRTLEDSGTVTSVLIPWNTCGAYQSGVLGVGVGEYFFYAIFNWLSPFMTLTFAALSIKIRMRSKTNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIW9</accession>
    <name>A0A5C6ZIW9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_05460</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="233" mass="25467" checksum="1D8E70D2ACE55188" modified="2019-11-13" version="1">MIQINELTKKYGDATALENLNLKVGKGEIFGLLGANGAGKSTTINTLLGFINPDSGSVQINEIDTVKNAQETRKLIGYIPENVNLYPYLSGLENLDYFCKLAGLKYTKSELEEFLSTCGLETKAHAKKVSGYSKGMRQKVGIAIAYAKKAQVYLLDEPASGLDPLASNELSVLLKKLAAEGATILMASHDIFRVREVCNRIGILKNGILVKELNSQDVSANELETLYLKFMQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ47</accession>
    <name>A0A5C6ZJ47_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_09130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026669">
        <property type="entry name" value="Arsenite_MeTrfase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43675">
        <property type="entry name" value="PTHR43675"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltranfer_dom" evidence="1">
        <location>
            <begin position="71"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="245" mass="26881" checksum="62F1C37EE045AF09" modified="2019-11-13" version="1">MLNDKITADYSKIVSSHELDAEAQRANACPAIFNSIRHRYPTFKGCIAEADLGLGCALPFEHANLKEGDLVADLGCAAGIDSFIMADLAGTKSQVFGFYITPSLIKRANAIKNNFGIEQVQFATADITEIPLEDDSVSVCTSNGVFSLIKDLEAVFKEIKRILRPGGVFCLSDINRKTNFSEVDYAQIKSYTGCLNGIRHQNSYLDHIKNAGFSSVELIGERLVEFPNHISKTQGVYISTFKITL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJD6</accession>
    <name>A0A5C6ZJD6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">VOC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06588">
        <property type="entry name" value="PhnB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028973">
        <property type="entry name" value="PhnB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06983">
        <property type="entry name" value="3-dmu-9_3-mt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3-dmu-9_3-mt" evidence="1">
        <location>
            <begin position="4"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="132" mass="15272" checksum="04B1A3F8CA642D96" modified="2019-11-13" version="1">MNVQAYLAFNGNCQEALNFYSKIFSAEIKNRQTYEDRKIDVPSSFRQKLQHAELKGKGLHFMAYDAAPDTPINHGNQIHMSVDLKNTEEAEDMFNQLSNGGQVHHNFREREWGHFGRCSDKFGINWMVNCDT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJG9</accession>
    <name>A0A5C6ZJG9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">GDP-mannose 4,6-dehydratase</fullName>
            <ecNumber evidence="3 4">4.2.1.47</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">GDP-D-mannose dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">gmd</name>
        <name evidence="6" type="ORF">ESY86_07975</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>GDP-alpha-D-mannose = GDP-4-dehydro-alpha-D-rhamnose + H2O</text>
            <dbReference type="Rhea" id="RHEA:23820"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:57964"/>
            <dbReference type="EC" id="4.2.1.47"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.47" evidence="3 4"/>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008446">
        <property type="term" value="F:GDP-mannose 4,6-dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070401">
        <property type="term" value="F:NADP+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019673">
        <property type="term" value="P:GDP-mannose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00955">
        <property type="entry name" value="GDP_Man_dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006368">
        <property type="entry name" value="GDP_Man_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43715">
        <property type="entry name" value="PTHR43715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01472">
        <property type="entry name" value="gmd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="5">
        <location>
            <begin position="7"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD89709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="372" mass="42642" checksum="1E4A4C7DC2086163" modified="2019-11-13" version="1">MQKKIALITGVTGQDGAYLSEFLLKKDYIVHGIKRRSSLFNTDRIDHLYQDPHVENQNFFLHYGDLTDSTNLIRVIQEVQPDEIYNLAAMSHVAVSFEMPEYTANADGIGTLRLLEAIRILGMEKKTKIYQASTSELYGKVQEVPQTETTPFYPRSPYAVAKMYAYWITVNYREAYGMYACNGILFNHESPIRGETFVTRKITRATSKIVLGLQDKIFLGNLDAQRDWGHAKDYIRMMWMILQADEPEDWVIATGVTTTVRDFVKMCFGHVGIELEFKGEGAAEKGYIKTCNNAEYNLEIGKEIVAVDEKYFRPTEVELLIGDATKAREKLGWIPEYDLAALVTDMMSSDLDLMHKQQYLKDGGYRIKNYFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJH2</accession>
    <name>A0A5C6ZJH2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Sec-dependent nitrous-oxide reductase</fullName>
            <ecNumber evidence="1">1.7.2.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">nosZ</name>
        <name evidence="1" type="ORF">ESY86_11160</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.7.2.4" evidence="1"/>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050304">
        <property type="term" value="F:nitrous-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001505">
        <property type="entry name" value="Copper_CuA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011045">
        <property type="entry name" value="N2O_reductase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026468">
        <property type="entry name" value="Nitrous_oxide_Rdtase_Sec-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041114">
        <property type="entry name" value="Nos_propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18764">
        <property type="entry name" value="nos_propeller"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50974">
        <property type="entry name" value="SSF50974"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04246">
        <property type="entry name" value="nitrous_NosZ_Gp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00078">
        <property type="entry name" value="COX2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="653" mass="72559" checksum="F90493E4B8AA1D1B" modified="2019-11-13" version="1">MKNILKTSVALVSILIGFTSCNNSGKSNGGSGALASNVAEKVYVPPGEYDSHYAFMSGGYSGNLTVYGLPSGRMFKEIPVFSQFPTNGYGYTEETTPMLETSYGFVPWDDSHHPDISQTDGVLDGRWIFINGNNTPRIARISLTNFETEEIIEVPNSAGNHSSSYITENTEYVVAGTRFSVPVPQRDMPIKDYKGNFKGALTFISVDPEEGHMDIKFQILMPGFNYDLSHPGRGKSHGWFFFTTYNTEEANSLLEVNASQNDKDFIAAINWKKIEEYVNNGGGTMMPANYAHNLYDEDTHMATSTMKKEVRVVNPSEVPGAIYLLPTPKSPHGVDVDPSGEYIVGNGKLSANLTVHSFTKMIDAIENKEFDGDAYGIPIIKFEDVLAGSVEQAGLGPLHTEFDGKGNGYTTFFISSEVVKWKLGTWEVLDRKPTYYSVGHLTIPGGNSREPFGKYMFAMNKITKDRYLPVGPEMEHSAQLYDISGDKMELLLDFPTHGEPHYAAAIPAEIIMNNVKKIYRLDENEHPRKATNESETKVVREGKNVHIYMTTIRSHFSPDNIEGVKVGDKVFFHVTNLEQDFDVPHGFAVIGANTAELLVMPGQTRTLTWEPKQVGVWPFYCTDFCSALHQEMQGYVRVSPADSNLDLSWSLGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJI5</accession>
    <name>A0A5C6ZJI5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 10 14">Catalase</fullName>
            <ecNumber evidence="3 10 14">1.11.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">ESY86_06895</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Serves to protect cells from the toxic effects of hydrogen peroxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 14">
            <text>2 H2O2 = 2 H2O + O2</text>
            <dbReference type="Rhea" id="RHEA:20309"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="EC" id="1.11.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10 12">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the catalase family. HPII subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.6" evidence="3 10 14"/>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004096">
        <property type="term" value="F:catalase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03132">
        <property type="entry name" value="GATase1_catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1370.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018028">
        <property type="entry name" value="Catalase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024708">
        <property type="entry name" value="Catalase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024712">
        <property type="entry name" value="Catalase_clade2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043156">
        <property type="entry name" value="Catalase_clade2_helical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011614">
        <property type="entry name" value="Catalase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002226">
        <property type="entry name" value="Catalase_haem_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010582">
        <property type="entry name" value="Catalase_immune_responsive"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041399">
        <property type="entry name" value="Catalase_large_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020835">
        <property type="entry name" value="Catalase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42821">
        <property type="entry name" value="PTHR42821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00199">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06628">
        <property type="entry name" value="Catalase-rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18011">
        <property type="entry name" value="Catalase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038927">
        <property type="entry name" value="Catalase_clade2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00067">
        <property type="entry name" value="CATALASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01060">
        <property type="entry name" value="Catalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56634">
        <property type="entry name" value="SSF56634"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00437">
        <property type="entry name" value="CATALASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00438">
        <property type="entry name" value="CATALASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51402">
        <property type="entry name" value="CATALASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10 13" id="KW-0349">Heme</keyword>
    <keyword evidence="9 10 14" id="KW-0376">Hydrogen peroxide</keyword>
    <keyword evidence="8 10 12" id="KW-0408">Iron</keyword>
    <keyword evidence="6 10 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 10 14" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Catalase" evidence="15">
        <location>
            <begin position="28"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="75"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="358"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="12">
        <location>
            <position position="362"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="369"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR038927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR038927-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR038927-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR038927-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="TXD89919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="710" mass="80572" checksum="D111A3C552B17C00" modified="2019-11-13" version="1">MSKTSNDKNKKTADLKKFEKDYENKTLTTNQGLKVNDTNNSLKSGERGSTLLEDFLLREKISSFDHERIPERIVHARGSGAHGYFELYDSIEQYSKAGIFTDTTRKTPVFARFSTVAGSKGSTDLARDVRGFAVKFYTEEGTWDLVGNNMPIFFIQDAIKFPDLIHAVKPEPNKEIPQAASAHDTFYDFVSRTTETMHNQIWLMSDRAIPRSLRMMEGFGIHTFRLINDKGESHFVKFHWKPKLGVHSVTWDEAVKISGADSDFHRRDLWDAIESGQFPEWELGIQIVPQEDEHKFDFDLLDPTKLIPEEMVPVQLIGKMTLNRNPENFFAETEQVAFLPGHIVPGIDFTNDPLLQGRLFSYRDTQLSRLGSPNFHQIPINRPVVDVHNNQRDAQMQMEIPKGQTAYFPNSLGGGCPHLAKMEEGAFHSYEERIDAKKIRGRSASFSDHFSQPALFYQSLAKWEQEHLKEAYIFELGKCTHQHIQERMLYIIDKINKDLAKKVAKGLGIAIPKSIEEPLNQAIGADADVAKFQPSKKIHYLDDAPTLSQANTKFDSIATRQIAVLVGDGFSMSDFKKMTAVLKNEAAVIKIIAPHGGQIKCDEGMEHKVDASIATTESVLYDAIYIPGGKASIDALMKEKKFIKFINEAFKHCKAIAVDHEAKQLLEETYVLDFEEDEAIFIDAKPQDFKKAIAKHRNWNRMENAKKIPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJK8</accession>
    <name>A0A5C6ZJK8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">S-adenosyl-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_09360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045755">
        <property type="entry name" value="FtsL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19579">
        <property type="entry name" value="FtsL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="107" mass="12182" checksum="DEFFD637BB38A4F3" modified="2019-11-13" version="1">MRNNIYSILRGKFLVSDDAFKNWRVIIFISVLAIVMIASSHSADQKVYEIAKMKNEVKELRSAFVDGRSKLMRLKMESSIIEKVAEDGIVISEIPPRKIKVKSSIPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJR1</accession>
    <name>A0A5C6ZJR1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_05500</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039426">
        <property type="entry name" value="BtuB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30069">
        <property type="entry name" value="PTHR30069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023141048" evidence="5">
        <location>
            <begin position="21"/>
            <end position="799"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="7">
        <location>
            <begin position="125"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="6">
        <location>
            <begin position="346"/>
            <end position="797"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD90196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="799" mass="90280" checksum="07028C7FF8AA40EB" modified="2019-11-13" version="1">MRTYAFLILLLCSISSISQNCDNTLSGTVTDLHDGSLLVGAILIVAGSEKAVQTDINGKFTISNLCNDTYSIQVSHPYCLAKGFTVKIAGNTTKNFKLEHHLEELNQVTVEGKAFSNKSKTILENTISKEELERFSSGTLGDALNSLSGVSSLNTGNTVIKPLINGLHSSRVVIINNGVRMEDQEWGAEHAPNVDINSVGNLTLIKGAGALQYSGDALGGVIIAEASKVPVKDSLYGKTLFTAASNGRGSSITSQLTKSYQSGWYGTVQGTLKRFGDFEAPDYVLSNTGIFERNASLLFGFNHFDYGIEGYYSFFKNEIGILRASHLGGAQDQIRAINSDRPLIINDFTYDIDAPKQDVTHHLARIKGFKRFDSFGKLSLQYDFQRNNRLEFDIRRGDDRDKASLDLELDTHTLLLDLDSDLTDEINLKTGLMARYQNNFADPNTGVRRLIPDYDKYDLGIYAIADYRWNDNLLLEAGGRFDYTYMDAFKFYRTSFWESRNYDELFPEIVVEELANQILTNPQLNFYNASATLGATYDFDDEYKLFFNYSLASRAPNPSELFSEGLHHSASRIELGDLRFNSEIGHKIALTFQRDNDVFGFSINPYINTINDFIIIEPTEIQQTVRGNFQVWEYRQTNAQLLGVDVDASYAFAKAFRFNHQFSFIKGYDRTRDEPLISIPAINTKNEVVYQNPDLKNLRLALQSEYVFRQNEFPDNNFEVFIPQTETMETVDVSTPPDAYHLLNFNSSIDFNINKKSKLTVGFSVANLFDTSYRNYLNRLRYYADDLGRNFLLNLKINY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJX7</accession>
    <name>A0A5C6ZJX7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_06575</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="78" mass="9241" checksum="974492FC2AE7C532" modified="2019-11-13" version="1">MSKLKLIWDFRGPDALKIAEHHVKHLNEYIAIQKTDLNITDFQQVHEMHSIAYMVVTQEEMKPIRDALKPHRGEIYND</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKI6</accession>
    <name>A0A5C6ZKI6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF2059 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_07800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018637">
        <property type="entry name" value="DUF2059"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09832">
        <property type="entry name" value="DUF2059"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022983152" evidence="1">
        <location>
            <begin position="19"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2059" evidence="2">
        <location>
            <begin position="73"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="135" mass="14948" checksum="DAB819B015776F1B" modified="2019-11-13" version="1">MKKLLVAIAFVCAFSVQAQEENSVFKNQTIEFIKLTGTADAFDNAIAQIGAQVPEAKMADFKKEANGTLDELYSKIADLYMKEFTEEDIAELVVFYKTDLGEKLASKQTTLTQSAMMVGQTWGMKVGQIAQKYAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKP3</accession>
    <name>A0A5C6ZKP3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">DUF421 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_06920</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UPF0702 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.240.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007353">
        <property type="entry name" value="DUF421"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023090">
        <property type="entry name" value="UPF0702_alpha/beta_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04239">
        <property type="entry name" value="DUF421"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="25"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD89924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="186" mass="20742" checksum="9588E7A0E3DDAE95" modified="2019-11-13" version="1">MIHSIFFSSDTSNLLDKLFATTSKTLILIAVSTLGIYSVIILYTRLFGKRSFSKISSFDFAMTVAVGSMTATVILSDSVSFLEGATGLASIYAFQLLAAIMRRYKWFRKLIDNQPTLLMDGRNILTENMKAVRVTEGDLRSKLRESNVTALSQVKAVIFETTGNIVVLHNSGNDEIEDWLLKDVQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKP4</accession>
    <name>A0A5C6ZKP4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Efflux RND transporter permease subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_02795</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="366"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="390"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="415"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="470"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="509"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="540"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="562"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="586"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="617"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="650"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1059"/>
            <end position="1078"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1085"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1126"/>
            <end position="1146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1187"/>
            <end position="1205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1211"/>
            <end position="1239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1255" mass="140110" checksum="DB42AF7E4C2460A1" modified="2019-11-13" version="1">MLNKSIKFLIENKLVAVLLLALFVGWGIVNAPFNWDTGILPTDPVSVDAIPDIGENQQIVFTKWQGRSPQDIEDQITYPLTTSLLGIPGVKTIRSSSMFGFSSIYIIFEEDIEFYWSRSRILEKLNSLPSGLLPNDVNPALGPDATGLGQIYWYTLEGRDKDGNVTGGWDLHELRSIQDYYVKYGLSSASGVSEVASIGGYVQEYQVDVDPEKMRQYNIDLSAIVKAVKESNQDIGAQTLEINQAEYLVRGLGYVKSIEDIENAVVTSENFTSLRIKDIAKVHLGPQTRRGILDKEGAEVVGGVVVARYGANPLEVINNVKEQIAELSTGLPTKVLEDGRISQVTIVPFYDRTELIQETLHTLNEALTLEILITILVIIVMVFNLRASILISGLLPVAVLMVFIAMKLFDVDANIVALSGIAIAIGTMVDVGVILAENMIRHLEDEKLRFQENGVEYTTNEIIYNATAEVSGAILTAVLTTIISFIPVFTLMGAEGKLFRPLAFTKTMALTAALIIALFLIPPFAAYLFRKTNIRERSKYILNGVLIMLGIAAIIYGYWLGLTLIGFGVVALLSVRKIVTAKRANLIHIIISCIAIVFLLAEYWRPLGFDRSIIMNLIFVSIICFGLLGIFSVFRRYYDDILRWALHNRLLFLIIPTTVLILGILIMRNTGKEFMPALNEGSFLLMPTSLPHAGVEENKRVLQQLDMAVASIPEIETVVGKAGRTESALDPAPLSMYENMIQYKSEYMRNENGGRQRYRVNDDGLFILKNNKFIINPNNEIDDDANYEASQLKTSASHDDLIADDDGEYYRNWRPDINSPDDIWNEIVKVTKFPGVTSAPKLQPIETRLVMLQTGMRAPMGIKVKGPDLKTIEAFGLELEDILKQAEGVKKQAVFADRIVGKPYLLIDIKRDQLARYGISVMDVQEILQVAVGGMPLTQTVEGRERYGIRVRYPRELRENPEDLKSIYVPVEKGSPVPLGELVDIRYEQGPQVIKSEDTFLIGYVLFDKLDGFAEVDVVENAQALIQQNIDNGDLIVPQGISYRFTGTYENQLRAEKTLSVVVPLALIIIFLILYFQFRSVSTSLMVFSGIAVAFAGGFIMIWLYGQDWFFNFSFFGENMRDLFNVKTINLSVAVWVGFIALFGIATDDGVVMATYLTQSFDRENPTDKKGIRHATLEAAGKRIRPCLMTTVTTILALLPILTSTGKGSDIMIPMAIPIFGGMIIDITSYFLVPVLFSWREEMKLKKKRRIEARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKR8</accession>
    <name>A0A5C6ZKR8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05545</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000801">
        <property type="entry name" value="Esterase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00756">
        <property type="entry name" value="Esterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="363"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="407" mass="47588" checksum="E7E731F46BD901F3" modified="2019-11-13" version="1">MRKSKIVITIITVFLCFKGIAQFNQNDEKQIVIGKVDSLYSKILQEQREIWVHIPEDFDNTKQYPVIYVLDASQNFYVITGMLKQLLPWQIPNSIVVGIINTDRTRDFTHTNVPFQRGHESETSGGASNFIKFIDEELKPFINNKYPTENNSTIIGHSTGGLFVLYSFLHHENSFDNYLAIDPSLWWDKENLVKETQELLNKGNRKEKSLYVAVANSIGKAMDTVKVRKDKTEPTEQIRANLKFHDLLVKNNKELNFKWEYFNNEDHGSVVIPAQYNGLRSIFSWFPFPEMWRFNTPKEFTSKQLTEPFQTHYKKLSIRMKREVKPDWELLNQVGFFMLDGHNLPKKALAYLELNAEFYPNQSKSFVALGNYYLSQKNKSEAIKHYKKAVEMDDNQEAQTKLKEIDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKV1</accession>
    <name>A0A5C6ZKV1_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 8">UDP-glucose 4-epimerase</fullName>
            <ecNumber evidence="5 8">5.1.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">galE</name>
        <name evidence="10" type="ORF">ESY86_02595</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>UDP-alpha-D-glucose = UDP-alpha-D-galactose</text>
            <dbReference type="Rhea" id="RHEA:22168"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:66914"/>
            <dbReference type="EC" id="5.1.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 8">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Carbohydrate metabolism; galactose metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the NAD(P)-dependent epimerase/dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.2" evidence="5 8"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00214"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003978">
        <property type="term" value="F:UDP-glucose 4-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006012">
        <property type="term" value="P:galactose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd05247">
        <property type="entry name" value="UDP_G4E_1_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005886">
        <property type="entry name" value="UDP_G4E"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01179">
        <property type="entry name" value="galE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7 8" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="9">
        <location>
            <begin position="5"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD90867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="340" mass="37253" checksum="8CFA5715EF0759D5" modified="2019-11-13" version="1">MKKILVTGGLGFIGSHTVVELQNEGFEVVIIDDLSNSSEAVLDGIASITNTTPIFEKLDMKDKNALHSFFEKHHDIAGVIHFAASKAVGESVNNPLLYYENNINTLVYVLQELLNLDASNLIFSSSCTVYGQADEMPITESAPVKPAESPYGNTKQIGEEIIADTCKVTEKLNAIALRYFNPIGAHPSAKIGELPIGVPQNLVPFITQTGAGLRDCLSVYGKDYPTSDGTCVRDYIHVVDLAKAHVIALKRLINKNNDANFETFNVGTGVGSTVLEVIESFERVSGKHLNYKFVSRREGDVISAYANTKKANNDLGWKAKSSLDDAMRSAWDWEQKIRNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL32</accession>
    <name>A0A5C6ZL32_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DUF3365 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_04940</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021796">
        <property type="entry name" value="DUF3365"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11845">
        <property type="entry name" value="DUF3365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0349">Heme</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome c" evidence="5">
        <location>
            <begin position="34"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD90097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="336" mass="37546" checksum="CD700D3861F07BD7" modified="2019-11-13" version="1">MKKTILLSMLLVSFLSCKNSEKTEYVAAEEIEDAQPHPGKKLMETNCYVCHSPSASQADRIGPPMIAVKKHYINESSTKAAFISDLQAWIKNPTAAHAKMYGAVKRFGVMPKTVYPEETIALIGDYMFDNAIEQPEWFEAHFNGAKGKGKGAKNGMGKAKSKQMQKQQAAIDFENLSYAERGLKYAMTTKAVLGKNLMQAIQNEGTLGALAFCNEEAYPLTDSMAVVLHASIKRVSDKPRNQNNQANDEELEYIETFKQVIANQEEPNPIVKELDDKVQVYYPITTNTMCLQCHGKPNKTMQAATLQKISLLYPKDNAIGYDVNEVRGIWRISFDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLG1</accession>
    <name>A0A5C6ZLG1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_08845</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014942">
        <property type="entry name" value="AbiEii"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08843">
        <property type="entry name" value="AbiEii"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="260" mass="30092" checksum="6A49A69CA34FDD69" modified="2019-11-13" version="1">MYRYSNDKTKCALLFNCASAVALELLKGGIKPSRGTKDIDFAIMVSSIQEFESIVKELSNYGFNKVEAPWTLYNDKFNIVIDLMPFGEIEEKFTVNFNERYTDLHVLGFSEVLEKPETVQIEEKSLQIPSLAGMVILKLIAWSDRPEDRDNDLYDVLRIIEHYFDLNYDNILEHHNDTFTEVEIFDQLKISARVLGRNSSEFLNVSEAIKERILNTINDNVDDAENSAIAKEWVKNKDWDLEYAVQLLKEFRAGLMDNLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLK0</accession>
    <name>A0A5C6ZLK0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">M15 family metallopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_06005</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009045">
        <property type="entry name" value="Hedgehog_sig/DD-Pept_Zn-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003709">
        <property type="entry name" value="Pept_M15B"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02557">
        <property type="entry name" value="VanY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55166">
        <property type="entry name" value="SSF55166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023021111" evidence="1">
        <location>
            <begin position="27"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="VanY" evidence="2">
        <location>
            <begin position="50"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="243" mass="28311" checksum="D6FCD874AF4F441B" modified="2019-11-13" version="1">MDRKKFIQASLLGSLGIALMPQLSFAVNTEISYEELIGKGQPELFGTGYQLRKETNEAFIKMAAEALKSDIKIQVVSSYRSFEHQNRIWERKYKRYQNQGLSPEAGIAKIIEYSTIPGTSRHHWGTDLDIIDAHVRQPSSVLQAQHFEENGCYRKLKLWMETHAKSFGFFLVYTKEPSRKGFKYEPWHYSYRALSQGYLQTYKTFDLKTIISKEQLMGHDYFSEAFINAYLKEHMLDINPDLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLR4</accession>
    <name>A0A5C6ZLR4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transferase hexapeptide repeat family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_01860</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="198" mass="21842" checksum="521A614B7440C909" modified="2019-11-13" version="1">MIYSFKDFIPVIHESSFVHPLAAVTGNVIIGKNCYIGPGAAIRGDWGQIILEDGVNVQENCTVHMFPGKSITLKESAHVGHGAIIHGANLGRNCLIGMNSVIMDDAEIGDESIIGAMSFVKAETKIPKRSLVVGNPAKVIKQVSDDMIAWKTKGTQLYQQLPTDCHESLREVQPLRTVPENRKLQEDVYKTLRDFMKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMA2</accession>
    <name>A0A5C6ZMA2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">bshA</name>
        <name evidence="3" type="ORF">ESY86_00285</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071793">
        <property type="term" value="P:bacillithiol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023881">
        <property type="entry name" value="Thiol_BshA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03999">
        <property type="entry name" value="thiol_BshA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="11"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="195"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD91072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="378" mass="42361" checksum="80EC31CA9708AE59" modified="2019-11-13" version="1">MKIGIVCYPTFGGSGVVATELGLELSKRGHEIHFITYSQPVRLDLLGNNVHYHEVNVPEYPLFLYQPYELALSSKLVDMVKLHQIEVLHVHYAIPHAYAAYMAKQMLKEEDINLPIVTTLHGTDITLVGSHPFYKPAVTFSINKSDAVTSVSQSLKEDTERLFNIKKDIKVIPNFIDLSKYEPKFTDCQRGMMATEDERIITHISNFREVKQIPDVIKIFNEIQKQMPAKLMMVGEGPERIPAEELCEKLGISNKVVFFGNSNEIDKILCFSDLFLLPSRTESFGLAALEAMASGVPVISSNTGGIPEVNIDGVTGFLSDVNDVESMSKNAIYILSDPKRLQEFKDHAKKASSKFAIAEVVPMYEAIYKETIRKSLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMG1</accession>
    <name>A0A5C6ZMG1_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">Cysteine synthase</fullName>
            <ecNumber evidence="5 11">2.5.1.47</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">cysM</name>
        <name evidence="13" type="ORF">ESY86_05080</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>hydrogen sulfide + O-acetyl-L-serine = acetate + L-cysteine</text>
            <dbReference type="Rhea" id="RHEA:14829"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:58340"/>
            <dbReference type="EC" id="2.5.1.47"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 9 11">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine from L-serine: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the cysteine synthase/cystathionine beta-synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.47" evidence="5 11"/>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00136">
        <property type="reaction ID" value="UER00200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004124">
        <property type="term" value="F:cysteine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005856">
        <property type="entry name" value="Cys_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005858">
        <property type="entry name" value="CysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001216">
        <property type="entry name" value="P-phosphate_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10314:SF100">
        <property type="entry name" value="PTHR10314:SF100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01136">
        <property type="entry name" value="cysKM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01138">
        <property type="entry name" value="cysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00901">
        <property type="entry name" value="CYS_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8 11" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="7 9 11" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PALP" evidence="12">
        <location>
            <begin position="7"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="9">
        <location>
            <begin position="173"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="10">
        <location>
            <position position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR605856-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR605856-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TXD90123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="292" mass="31791" checksum="C23A189F3D0042F1" modified="2019-11-13" version="1">MNKTIIDLIGNTPLVKSMVLNTNPNVSLYFKLEGNNPGGSVKDRAAYNMIKTALDTGQIDKTSKLIEATSGNTGIALAMIAGIFKLEIELVMPVNATKERVQTMKAYGAKVTLHPDGIEGARDYVIEKVENEGYYTFDQFANENNWKAHYKTTGPEVWRDTNGEVTHFVSSMGTTGTIMGTSSFLKEQNKNIQIVGVQPTDGSSIPGIRKWAEAYLPKIFNASKVDRTIEVSEDEAVAMTKRLAKEEGIFAGMSSGGATTAALKLANELESGVIVSIICDRGDRYLSSDLFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMG8</accession>
    <name>A0A5C6ZMG8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Carboxypeptidase-like regulatory domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_00005</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="197" mass="23143" checksum="745465D70B9E1EBF" modified="2019-11-13" version="1">MKKLILTILFLNSIIGFSQNEKSNEIVIKGIVLSEVNGKPLENVYLSYKSRYRYSATDEKGKFEYKYKIREKDSLETIELTALGYENIDTIVRVDKPKEYVFEFVMKPRFGLNREKAIEDIKNGKVNILESSGIAPVFYKSDTKFAKKYNVNFVEYGCEAVAWESLYEYNRAVFEYLDKKYGKKWRKKIRKDIVGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMS4</accession>
    <name>A0A5C6ZMS4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043165">
        <property type="term" value="P:Gram-negative-bacterium-type cell outer membrane assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007485">
        <property type="entry name" value="LPS_assembly_LptE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04390">
        <property type="entry name" value="LptE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="168" mass="18915" checksum="B6E3D6DCD0C1FC5B" modified="2019-11-13" version="1">MKLIKYILAFCSLPMFLGCGAYSLSGISIAPNIETFQVNYFQNSAILVEPGLDRDFTLALQDLILNQTNLSLTNTNGDLVYEGEITEYRISPTTAQANSTAAQSRLTIAVRVRFYDQSKPEEEFEQSFSFFYDYTGSAQLVGNLKDTAIEEIFERLTQDIFNATLAQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN47</accession>
    <name>A0A5C6ZN47_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA mismatch repair protein MutS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">mutS</name>
        <name evidence="10" type="ORF">ESY86_02675</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the DNA mismatch repair MutS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00096">
        <property type="entry name" value="MutS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005748">
        <property type="entry name" value="DNA_mismatch_repair_MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007695">
        <property type="entry name" value="DNA_mismatch_repair_MutS-lik_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017261">
        <property type="entry name" value="DNA_mismatch_repair_MutS/MSH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007861">
        <property type="entry name" value="DNA_mismatch_repair_MutS_clamp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016151">
        <property type="entry name" value="DNA_mismatch_repair_MutS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007860">
        <property type="entry name" value="DNA_mmatch_repair_MutS_con_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036678">
        <property type="entry name" value="MutS_con_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS_family"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="PTHR11361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01624">
        <property type="entry name" value="MutS_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05188">
        <property type="entry name" value="MutS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05192">
        <property type="entry name" value="MutS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05190">
        <property type="entry name" value="MutS_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037677">
        <property type="entry name" value="DNA_mis_repair_Msh6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="SSF48334"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53150">
        <property type="entry name" value="SSF53150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55271">
        <property type="entry name" value="SSF55271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01070">
        <property type="entry name" value="mutS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00486">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 7 8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 7 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_MISMATCH_REPAIR_2" evidence="9">
        <location>
            <begin position="692"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="618"/>
            <end position="625"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD90880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="870" mass="97569" checksum="15AB3DDAF2350387" modified="2019-11-13" version="1">MAKKAKKETPLMKQYNAIKVKYPDALLLFRVGDFYETFGADAVKASKILDIILTKRGAGSETETELAGFPHHSLNNYLPKLVKAGCRVAICDQLEDPKQTKTIVKRGVTELVTPGVALNDDILHSKTNNFLASVYFGVNQVGVSFLDVSTGEFLISQGNAEYVDKLLQNFRPSEVLVAKPNKNKYKAEFGNDFHAFFLEDWVFQEDYANEILLKHFNTKSLKGFGIDDLFEGIGAAGAILHYLSETQHHKLAHITSIQRLTKGEHVWMDRFTIKNLELYHSNNQNAVTLVDVIDKTISPMGGRLLKRWLALPLVNLEQIKDRHDVVSFLKSETILLSKFQLQLKQIGDIERLISKVATGKICPREVVQLKNALEAIVPIKSLATASKNSALNAIGETMDACEGLRQRIKATLNEEAPVNILKGNTIASDFSSELKELRGLSASGKSYLDKMLARETERTGITSLKIASNNVFGYYIEVRHTHKDKVPADWIRKQTLVSAERYITEELKEYETKILGAEERILLIEQQLFAELINDMVAFIKPVQQTSTLIAKLDALCGFAQLATENNYSRPKLTETYALDIKNGRHPVIEKQLPHGEPYIANDVYLDREKQQIIMITGPNMSGKSAILRQTALIVLLAQMGSFVPAEAATIGLTDKIFTRVGASDNISMGESTFMVEMNETASILNNISDRSLVLLDEIGRGTSTYDGISIAWAISEYLHEHPSRAKTLFATHYHELNEMTETFDRIKNFNVSVKELKDNVLFLRKLVAGGSEHSFGIHVAKLAGMPQQVIHRANKILKQLEKSHSSEELTNKVKTLSNDMQLSFFNLDDPLLEQIKEEIINIDINTLTPVEALMKLNEIKRMLVKKKQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN65</accession>
    <name>A0A5C6ZN65_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00245</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="111" mass="12464" checksum="920A75E5E60A5E8E" modified="2019-11-13" version="1">MKYTNAAEEGKTRAIVAYITLIGTLIAYFLNKENNNPFVYFHVRQALGLWLLQLILGYFIGAFDSWMVTTAFWIAFISLFIYGIIGAANGQKNEVPIIGPFCQKLFSSIGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN73</accession>
    <name>A0A5C6ZN73_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">RagB/SusD family nutrient uptake outer membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_02840</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SusD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012944">
        <property type="entry name" value="SusD_RagB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07980">
        <property type="entry name" value="SusD_RagB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="SusD_RagB" evidence="5">
        <location>
            <begin position="384"/>
            <end position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD90910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="544" mass="61178" checksum="7C41285702252123" modified="2019-11-13" version="1">MNINYINNKAMMLRTIKNLLVVLTVAIFMQSCEDRLDLQPEDARLTADAAFENPEAYKEFLAKIYAGISLSGQEGPAGAPDLAGLDEGFSNYLRLYWKMQQLTTDEALIAWNDGTIQDLHGQVWTSGNEFIRTMYSRLMYQVALTNEFLRQTTEGKLNERGVNADLREEIQTYRAEVRFMRALTYWHAMDLFANPPFITENDAVGAFLPPQIQRADLFDYIESELLDIEDELVAPRQNEYGRADRAAAWMVLAKLYLNAEVYTGTSRYTEVITYSNNIINAGYTIPSTPYFYSFLADNDSNGAQSEVIFTIPFDGLRTQAFGGMTFMTHAPVGGSMDPANFGINGGWFGVRTTPTFVEQFPNEANSADGRELLYTDGQTKNIADVSTFTDGYAVAKYRNVDVNGDPGSDSSGDHTDIDFPMFRLADVYLMYAEAALRGGGGSMDLARGYINEIRERAYGDTSGNISQSDLTLDFIIDERSRELYWECHRRTDLVRFNQFSNNGVWQWKGGVQQGTTTEAFRNVMPLPATDLGINTNLEQNEGYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNB8</accession>
    <name>A0A5C6ZNB8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_01280</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="71" mass="8405" checksum="E75EF8D757598BAB" modified="2019-11-13" version="1">MTKSNKPQYTNFKQVDHDLKRLNLERKIAVEELKIVKSDYIEALSPYNWLQTGLKFAGKYGVFVLLKKLFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZND0</accession>
    <name>A0A5C6ZND0_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GTP cyclohydrolase 1</fullName>
            <ecNumber evidence="5">3.5.4.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">GTP cyclohydrolase I</fullName>
            <shortName evidence="5">GTP-CH-I</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">folE</name>
        <name evidence="7" type="ORF">ESY86_05470</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>GTP + H2O = 7,8-dihydroneopterin 3'-triphosphate + formate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17473"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58462"/>
            <dbReference type="EC" id="3.5.4.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homopolymer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the GTP cyclohydrolase I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.16" evidence="5"/>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00848">
        <property type="reaction ID" value="UER00151"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003934">
        <property type="term" value="F:GTP cyclohydrolase I activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035998">
        <property type="term" value="P:7,8-dihydroneopterin 3'-triphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.286.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00223">
        <property type="entry name" value="FolE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043134">
        <property type="entry name" value="GTP-CH-I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001474">
        <property type="entry name" value="GTP_CycHdrlase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020602">
        <property type="entry name" value="GTP_CycHdrlase_I_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11109">
        <property type="entry name" value="PTHR11109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01227">
        <property type="entry name" value="GTP_cyclohydroI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00063">
        <property type="entry name" value="folE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 5" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="GTP_cyclohydroI" evidence="6">
        <location>
            <begin position="39"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD90190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="218" mass="25190" checksum="6A31F7D9241A9C7F" modified="2019-11-13" version="1">MKKELIEEIGDNHILTNIETPLLSNAFEKSDEEKIENIQRYFSKIMQELGLDLKDESLSGTPYRFAKMYVKELFYGLNPINKPKLSTFPNKYGYKKMLVEQDITIDSSCEHHFLPITGHAHIGYVPNEKVIGLSKINRLVDYYSHRPQVQERLCLQILNDLQETLNTKNVIVVLNAKHLCVSSRGIKDKDSSTTTIEFGGCFEDIENRNEFFLTLNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNF8</accession>
    <name>A0A5C6ZNF8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PAS domain S-box protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_00770</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016772">
        <property type="term" value="F:transferase activity, transferring phosphorus-containing groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="2">
        <location>
            <begin position="19"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="3">
        <location>
            <begin position="95"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="1">
        <location>
            <begin position="162"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD91155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="381" mass="43378" checksum="7058D94E3D9EBAB3" modified="2019-11-13" version="1">MNQAEIEESDKEYSDLLHNKLIYKYALENSSIGVWDFDISKNHIHHSKESKSIYGYSISEFDYSQSDWRLRIHPDDLEELSKLVDAHLKGETTEYSSEHRIRCKDGSYKWILDRGKIIAFDINGNPTRFIGTTLDITKKKAEEEESVQNLMIISNQNKKLNNFAHIVTHNLKEYAGNFESLLTFYDEAQTNAEKSDLVEHLKTVSKSLSNTIKNLNEIVQRQSKTNIDCELLNVNAYIDKISKLLDLEIASKNATINNNVSDQLFLYSNPAYLESIIFNLASNALKYAHPDRAPIIDIDSKISQSEVLITIKDNGLGIDLEKHGESLFGLYQTFHGNENSEGIGLYITKNQIETLGGMIDVESQVGIGTTFKISIKEKKQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNI3</accession>
    <name>A0A5C6ZNI3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcription elongation factor GreAB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_04125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070063">
        <property type="term" value="F:RNA polymerase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032784">
        <property type="term" value="P:regulation of DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036953">
        <property type="entry name" value="GreA/GreB_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001437">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023459">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30437">
        <property type="entry name" value="PTHR30437"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01272">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GreA_GreB" evidence="1">
        <location>
            <begin position="54"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="139" mass="15825" checksum="29FD96885A294F0E" modified="2019-11-13" version="1">MKYGSLILEKKEYVYLKRILNISGYVGDHETQKSLVKLAEELKTAHIVDEEKMPKDVVRFNSHVKVSSDKGWERAFQVVIPVDKDFKLNKISVLTPMGSVLLGYSESDTVDWNLPGGNEKLKITSVRHEETYNGIDITL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNM8</accession>
    <name>A0A5C6ZNM8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2254 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_02920</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018723">
        <property type="entry name" value="DUF2254_membrane"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10011">
        <property type="entry name" value="DUF2254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="441" mass="50211" checksum="814EB701C44CBACC" modified="2019-11-13" version="1">MRQYYFSFLKTLERLESNIAFYPTLISLGGVTFAFFMIYLESIGISRYLVEAAPILVVNNTETARSLLTTFIGGLISIMVFSFSLVMILLNQASANFSPRVLPGLISNKRHQVILGIYNGTLLYSIFTLVSIAPHGDKYQMPGFSVLLGIIFMTMSLGAFIYFIHSISQQIQVGTIMDKIFKKSQARLLKLVESEKHLETDFEDTANWNEIMASQTGYMQDVSLNVLGTLAEEHQLKIEIVPIKGAYVLKGIPILKYKGDVDDELKEKLLDAVMFSKSELIEDNYVLAFKQITEIALKAMSPGINDPGTCINAIDYLTELFALRMTKKNKSFYFSEDDEALIYVRTVSFEQLLYNVMAALRTYCKHDIIVVQKLFTMLQYLLQNREVLRENYKESIISEIRNLKIDALANHENEADIKVINNIIKHLEDLNPSDYKFDSNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZP86</accession>
    <name>A0A5C6ZP86_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_03640</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the MlaE permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003453">
        <property type="entry name" value="ABC_MlaE_Proteobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030802">
        <property type="entry name" value="Permease_MalE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30188">
        <property type="entry name" value="PTHR30188"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02405">
        <property type="entry name" value="MlaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00056">
        <property type="entry name" value="TIGR00056"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="84"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="146"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="235"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD90470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="260" mass="28361" checksum="DD89AF62B1249DDB" modified="2019-11-13" version="1">MNTENAILSKTKSFFAEIGDMTLFAGRFFREVFSPPFEFKELMRQCYNMGNRSLLLVSVTGFILGLVFTLQSRPTLMQFGAQSWMASMVSLSIVREIGPVIIALICAGRIGSGIGAELGSMRVTEQIDAMEVSGTNPFKYLVITRIVATTLMLPLLIIMGDAIALLGSAIVENLKGNVSFLLYFNQVFDALKFSDLLPATVKSVFFGFAIGLVGCYKGYNCAKGTVGVGEASNSAVVYISMLLFIIDFIAVFVTDIFFDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPC0</accession>
    <name>A0A5C6ZPC0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_01380</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="7"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD91267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="146" mass="16403" checksum="F2F56FC1861F9692" modified="2019-11-13" version="1">MVNNTAEILLIEDNMNDAELTIRAFRKGNIKNTLIHLKNGVEALEFLFGTGQFEGRDISKKPKVILLDLKMPKVDGLEVLTQIKANELTKAIPVVVLTSSNEHPDIKRAYSLGANSYIVKPVEFDEFSKVVTDLGFYWLLKNQAQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPE5</accession>
    <name>A0A5C6ZPE5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_01080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="181"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="208"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="246" mass="29007" checksum="8A9A4C07DE107062" modified="2019-11-13" version="1">MSLNKFLVSLLITLSIVFVGLQYFQLEYEATLVRTVAMMSLAILYIRKVEKKHLFFYWFLMLFTIGDIFNLITWSYSVYIDSAYELPFYFIGNIIYIIAYTFLVLRMIASLNFVKAIKKFPLQVLILIILGVFCVYFVSDTTKRELETSQYLLEFAYNAVIMFLMCLALINYMYHDDKKSINLLIGSIFIVFSEVIQLAYFYVAEFRILNVLCSLFLVMAFIFFYLQSLLKHEPAGIYKYDKIHTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZQC1</accession>
    <name>A0A5C6ZQC1_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CIS_tube domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045361">
        <property type="entry name" value="CIS_tube_prot_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19266">
        <property type="entry name" value="CIS_tube"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CIS_tube" evidence="1">
        <location>
            <begin position="9"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF19266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="255" mass="29375" checksum="6D365786E04D09DB" modified="2019-11-13" version="1">MIKGILGIIDKMRIEVFPSSKYSEREILKTIFVQINPESYSETKNIEYYEDDVIGGSNTITTFKWVGQKRLSFDFIFDSSGVLPPARIEEGQADNFPVGDAVIEALKPAVTNPFDTPDSIHEKLTKFQEALVHYHGDAHEPRYLRLLWGKLLFECRVSNMQINYSLFRNDGQPIRATVTCEFIQSTSFNEILNQRNDASPDVTHEFTFKLQDRFPLLAEKVYENNNYYIDAARSNGLLSFRNVRVGEHIHFPPLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZQF1</accession>
    <name>A0A5C6ZQF1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Outer membrane beta-barrel protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_00760</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="185" mass="19711" checksum="438BF4B716387E4B" modified="2019-11-13" version="1">MASFVMNILKLFIMKKLILVAVVAVFGLANVNAQNFNAGISAGLPIGDFSDLYSFSVIVDVNYLWEVSEQFDAGVTVGYSHSFGKDEDLNLDLGDFGSFDIETEDFGYIPIGAAGRFNASEDFTIGLDLGYAIAVSPSGSDGGFYYAPKVQYGITQSLDIVAAYRGVSLDGGSFDIVSLGIEFGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZQN9</accession>
    <name>A0A5C6ZQN9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DoxX family membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_03030</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032808">
        <property type="entry name" value="DoxX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07681">
        <property type="entry name" value="DoxX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="9"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD90943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="137" mass="15676" checksum="C9144C38D8D1AA98" modified="2019-11-13" version="1">MKTTRVQNIFRILLALFMIYAGFSHLTFNRIEFQSQVPDWLPVSKDLVVILSGIVEMGLGLALLFWKKQRATIGWALALFFVLVFPGNIAQYLDGKDAFGALNSDTARLIRLFFQPVLIAWALWSSGAWQTWRHSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZRK1</accession>
    <name>A0A5C6ZRK1_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 9">Chromosomal replication initiator protein DnaA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 14" type="primary">dnaA</name>
        <name evidence="14" type="ORF">ESY86_01125</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 9">Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8 10">Belongs to the DnaA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006275">
        <property type="term" value="P:regulation of DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06571">
        <property type="entry name" value="Bac_DnaA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1750.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00377">
        <property type="entry name" value="DnaA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001957">
        <property type="entry name" value="Chromosome_initiator_DnaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020591">
        <property type="entry name" value="Chromosome_initiator_DnaA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018312">
        <property type="entry name" value="Chromosome_initiator_DnaA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013317">
        <property type="entry name" value="DnaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013159">
        <property type="entry name" value="DnaA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024633">
        <property type="entry name" value="DnaA_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038454">
        <property type="entry name" value="DnaA_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010921">
        <property type="entry name" value="Trp_repressor/repl_initiator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30050:SF2">
        <property type="entry name" value="PTHR30050:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00308">
        <property type="entry name" value="Bac_DnaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08299">
        <property type="entry name" value="Bac_DnaA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11638">
        <property type="entry name" value="DnaA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00051">
        <property type="entry name" value="DNAA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00760">
        <property type="entry name" value="Bac_DnaA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48295">
        <property type="entry name" value="SSF48295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00362">
        <property type="entry name" value="DnaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01008">
        <property type="entry name" value="DNAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7 8 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="12">
        <location>
            <begin position="172"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="Bac_DnaA_C" evidence="13">
        <location>
            <begin position="383"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="180"/>
            <end position="187"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TXD91220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="475" mass="54227" checksum="2AC9F61F5A9E7D1F" modified="2019-11-13" version="1">MELTAETVWKNCLSFIKDNIQPQAYKTWFEPIVAVKLTDNALSIQVPSKFFYEWLEEHYVKILKVSLTKELGETAKLVYVIKMENTYGNKQPFTEKIPSSNRSAMKSQDVDVPLNNKNPELRNPFVIPGIRNVKIESQLNPNYSFENFLEGDSNRLARNAGLAVANKPGGTSFNPLLIFGGVGLGKTHLAHAIGVDIKDKYPEKTVLYISAEKFTQQYIDSVKKNNRNDFIHFYQIIDVLIIDDVQFLSGKSGTQDVFFHIFNHLHQNGKQVILTSDKAPVDMQDIEQRLLSRFKWGLSAELQSPDFETRVSILKNKLYRDGVEMPDDIIEYVAKHIKTNVRELEGAIISLIAQSSFNKKEITISLAKEIVEKFVKNTKREVSIDYIQKVVSDYFQMDVSTLQSKTRKRHIVQARQLAMFFAKKYTKASLASIGSQIGKRDHATVLHACKTVDNLSSTDKQFRKYVEDLSKKLSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6Z9X3</accession>
    <name>A0A5C6Z9X3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sensor histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_19725</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000046">
        <property type="protein sequence ID" value="TXD86626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010559">
        <property type="entry name" value="Sig_transdc_His_kin_internal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06580">
        <property type="entry name" value="His_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="His_kinase" evidence="2">
        <location>
            <begin position="170"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="355" mass="41731" checksum="13378B841E5F1C3E" modified="2019-11-13" version="1">MDLDKKIVRVLNNKETKLFVLFYIVSAFIYYTATWISWGTYKKGFLSYFDVEEFFAAAGTQFMVSFLITIPIWYVTEVILREYTLKVRLLSHVFFLPIFILACYFGQLGVTKLFGWAMFWGGKYIVWTLYNLMLFYLVQFGFIHAYNYWIKLKNEELEKSELRELALKSEMTAMKAQLTPHFLHNLFNSINATIPPENERTRELIVQLSDLFRYLNYASQHEYVTIQEELSFIENYLQLMKIRLKERLKYSFEVPNHLKEYKIAPMLFQPIVENAVIHGISPKIEPSTLIVRIKKSSEKLLISIEDTGLGILDKENLFQKGLGLSNTKLRLNKIYDSDLKIDDNIPLGTIISFEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZA31</accession>
    <name>A0A5C6ZA31_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20720</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000108">
        <property type="protein sequence ID" value="TXD85941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002514">
        <property type="entry name" value="Transposase_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01527">
        <property type="entry name" value="HTH_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0814">Transposable element</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD85941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="103" mass="12078" checksum="84DB8E1119AEFFAA" modified="2019-11-13" version="1">MKYKKWTLEQKLEILSTSDEIGIVESCRKHGVSTGTFYSWKKKFEHNGEAGLKVTYDTKSKELKASEEENRVLRKLLSDREIELEVQRELLKKKFGTSDPRKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAK6</accession>
    <name>A0A5C6ZAK6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_18495</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000032">
        <property type="protein sequence ID" value="TXD86985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1264" mass="148238" checksum="BAE2613DD0E4692B" modified="2019-11-13" version="1">MVTTIIEKYLSSVDQATFQKLMNHLLHLEGYKFISSPGAVTGKNKTSKGSPDSFFEEEDNFIFCEYTTQERLATGETFFKKLKKDVDHCFDVKKTKVDKSKVSKVLLAFTEKIKPNEHKELQRKVKKHNPKAELIIYSIQEIPFRLVYYPGLADKYIAGVTTTKGTLYTLPDFLKTTEKGLQPSLINPFAGREVEIKQAKESLLSNDILIITGGQGVGKSKLAVHLAEIFERELSYEPRVIASSPVPLWEDLNNFILPSNKYFIFFDDANKALPNLDYLLQFINGREKGTTKIVITVRDYVRNDLNKYLLDALYNELIVKPLEDKQITEIINKSLPKDISLDPLVLERILSLSKGNSRLALMAVSSILKNNDIGILNDAFTLYDQYFQKVKTDLLFLDKPENLKALGILSFFGVLDRGNEEIKQILTKHFGIDWNELWETYLELEKVELVDIFHNEAAKISDQVLATYVFYKTFVDENSASINYSDWLNYFIAKYDKKINKTLIDIINTFGFVELKDRVTSLISNFHKQIESDEAKLFKFYEIFWFYREMDTLLFIRKWIDNLEIENTELEDIKYTYEVNDFVLAPEYLRLLINFWNHNTPFTKEAIELGLKLMFKQPSQVPEVLKHLKEHLAFHRYDFRYGYPRQLTLLNVLNKDSFSEREKAMAEKLFLSIVPSYLGWEFHQTEGKSGGQMMIYNFALVKNNSLMELRKIVLERMFCLFVKNEATVLATLHKYAWTVKSFDSTIYADEQSDITAFFQTNLKPENYAHCKLVHEYVNTLKEHNIEPLMDWDLFLNSDSMGIAKIFSSKFDDEKLKFEERDVKKKAEIKTFVADKDINFIETVFNRLDSIYQDAAKSRDTFWIDSSLSLLFQVLAESDSKIYYKSLELIMLGKHSFELNYGSVIQYPIRKELVKHKELYKHINRYEYKQKQFWKQIFFDAIDENAIDEFYLQEFIGFLFSVSNRFYIYEFDKKIKFEKQFHLSKSLLPPSALNHENVITYITEILLSKVDSIDITFDRQTCEKCVNHFNKKIGLLKQVFYLHKKRDPHYDHDGKEMAAVSSLDHFFLVEYLTEVTKDVSFIQFKFDSSNLTFVWGLPEYVDILDKSLEIIIAKAPIFSNFEHQANALFKGLKLDEKQLEKVYTYISRFISKHYGSKQHIHIILNVVTYSFNDQVLRFLKGFLQLNKDIEFMKCLWLEKNGAFSGSRVPRIEGHINFSNSIIEMIKTLPNPLDYAEHIKNFEQEIEWARQDKQVEMKRDFIGWTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAM0</accession>
    <name>A0A5C6ZAM0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Helix-turn-helix transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_18620</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000032">
        <property type="protein sequence ID" value="TXD87005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="94" mass="11112" checksum="45E61747D0519BB8" modified="2019-11-13" version="1">MDFPSLKDFALQIGTNEFKLKYGFKELYGTTVYRFLVQERLRKAQMMIQYSDLPLKSIAYMTGFKSMPHFSRTFKKRYGYSPSALRNNSIEDND</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAM7</accession>
    <name>A0A5C6ZAM7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19470</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000041">
        <property type="protein sequence ID" value="TXD86721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046219">
        <property type="entry name" value="DUF6252"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19765">
        <property type="entry name" value="DUF6252"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023017886" evidence="1">
        <location>
            <begin position="22"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="185" mass="20314" checksum="F3871995D5D1DDCD" modified="2019-11-13" version="1">MKKLKSMCLAILIIFPLWGLGGCNNDDDNNNNDTLPPATQIGANTVGCLVNGEVFLPKSEGINPAVVVNYEFINGEFYFSLTLNDLRGTGVKTVSVRTSEIDLETGGVYILDKDNTIFESFIGGGGVYGVDASNYFYTNSIKTGELTITRLDLSNSIISGTFWFDAINEESEIVEIRDGRFDYVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAS1</accession>
    <name>A0A5C6ZAS1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Alpha-ketoglutarate decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19245</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000038">
        <property type="protein sequence ID" value="TXD86791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="177" mass="20057" checksum="F519E4AC40BB5FD8" modified="2019-11-13" version="1">MEFLRLPAILKLSTVSVFLLLSHFIGAQDLRQNTDFWSHVRFGGGVGLNFGDGFFSGTLAPSAIYDYNRQFSMGIGLNATYSSQKNVFNATVLGGSLIGLFNPIDEIQVSAEFEQLNVSQNFDDPVFRDDNYWYPALFMGVGYRSRNVTIGVRYDLLYDDNKSIYANAWAPFMRFFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAZ3</accession>
    <name>A0A5C6ZAZ3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19975</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000053">
        <property type="protein sequence ID" value="TXD86530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="78" mass="9203" checksum="76AAE36D8B92317B" modified="2019-11-13" version="1">MKDKKESFLTTPTKKHLIIFGLLWFISIALLTLSITDLFTESFFQKNYIMMYFLMIGSTVATGKLYFNYWKNKTLDSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBN7</accession>
    <name>A0A5C6ZBN7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Alpha-hydroxy-acid oxidizing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_18915</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FMN-dependent alpha-hydroxy acid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000035">
        <property type="protein sequence ID" value="TXD86884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02809">
        <property type="entry name" value="alpha_hydroxyacid_oxid_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012133">
        <property type="entry name" value="Alpha-hydoxy_acid_DH_FMN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000262">
        <property type="entry name" value="FMN-dep_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037396">
        <property type="entry name" value="FMN_HAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008259">
        <property type="entry name" value="FMN_hydac_DH_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01070">
        <property type="entry name" value="FMN_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000138">
        <property type="entry name" value="Al-hdrx_acd_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00557">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51349">
        <property type="entry name" value="FMN_HYDROXY_ACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0288">FMN</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN hydroxy acid dehydrogenase" evidence="6">
        <location>
            <begin position="4"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="281"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="83"/>
            <end position="85"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="257"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="279"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="281"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="284"/>
        </location>
        <ligand>
            <name>glyoxylate</name>
            <dbReference type="ChEBI" id="CHEBI:36655"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="312"/>
            <end position="316"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="335"/>
            <end position="336"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000138-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000138-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD86884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="383" mass="42587" checksum="40F9A34DB05A8943" modified="2019-11-13" version="1">MALDFNTKYPSIDDLRNRAMQRIPRFAFEYLDGGCNDDVNIVRNTSELRDVQLKPNYLRSHHGSSMKTKLFGIEYDAPVGVAPVGLQGLIWPNAAEILAKSAFEHNIPFILSTVTTTNIERASELTEGKAWFQLYHPTEDRLRDDIINRAAAAQCPVLVILCDVPSFGYRPRDIRNGLAMPPKMSLSNILQVMGKPNWAIQTLKHGQPGFANLLPYMPKGLDLKQLGKFMDQTFSGRLNADKIKPIRDMWKGKLVLKGVANEVDVEEAIRLGIDGVIVSNHGGRQLDAGESSIRPLERIAKKYGDQIEVMMDSGLRSGPDIARAMASGAKFTFMGRSFMYGVAALGAKGGDHTISIIKTQLQQVMDQLCCERVEDFPNHLITK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBN9</accession>
    <name>A0A5C6ZBN9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19450</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000040">
        <property type="protein sequence ID" value="TXD86749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="190" mass="21838" checksum="AA53D4C72C9F8159" modified="2019-11-13" version="1">MNRLIQFFFVVSFLIQFSCESRSSKNSKLKNIESTTLNAQETISKKSDKNSIKILTWNIQDLGQSKDDDEILTIAKIIKPYDIIAVQEVVGKDPRGAQAVARIADNLNRMGNKWDYSISDPTKSPSTNMSERYAYFWKTSKVKLISKPYLDTELEDKCIREPYIAEFILKNGKDSFFIVNFIVYPQTALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBX6</accession>
    <name>A0A5C6ZBX6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_20365</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000067">
        <property type="protein sequence ID" value="TXD86361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="95" mass="11122" checksum="582F39DA9730EA3F" modified="2019-11-13" version="1">MQTHHIRFIDNSYDLEIAEQLLSRIISQKIAFLEDRIKETDPDDEDELNQLKLRISDLNAECRSLDLLIKEHDGEYVEMEIGCTIVMSIKKIETT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC29</accession>
    <name>A0A5C6ZC29_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000028">
        <property type="protein sequence ID" value="TXD87188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="24"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="67" mass="7567" checksum="19188E179B58DDD1" modified="2019-11-13" version="1">MSASSNYNRIKQVLVENNKSNKWLAEKLKMSETTVSNWCTNNRQPSLPTLFKIASALEISPKNLINA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC66</accession>
    <name>A0A5C6ZC66_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20475</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000079">
        <property type="protein sequence ID" value="TXD86231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045584">
        <property type="entry name" value="Pilin-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54523">
        <property type="entry name" value="SSF54523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="201" mass="23692" checksum="E36A49895AB65FA2" modified="2019-11-13" version="1">MKNLLPFIISFFLPGAGQFILKDFRKGGIILLLDIVSTYLILNLDFLNLIPFWFPHIIIMIWAIFDIYDKIEQRDGKKSATRYLAFSLLIVIILFPLSLTLFTTGLFKGVEFVTDEYLNEDRTKTEMNEISTELSLYENYYGVFPKNYESFIRQKPIWGSWKSDNWKNPYKYELIDSINYKLISAGKDGIYFNKDDIIRKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCA5</accession>
    <name>A0A5C6ZCA5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Gliding motility-associated C-terminal domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000029">
        <property type="protein sequence ID" value="TXD87137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026341">
        <property type="entry name" value="Bac_Flav_CTERM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04131">
        <property type="entry name" value="Bac_Flav_CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023003805" evidence="1">
        <location>
            <begin position="28"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="487" mass="52074" checksum="FD54329111622D22" modified="2019-11-13" version="1">MQKTTNLNRLLCVLCLIAVSITAQLNAQIVIGAPNLGFSQACASSTFNSYSATFVFSPASALGDTNQFIIEMSNEEGDFTDPTIVFTSQPNVFTTSPATINFSLPSTTSGEAYKIRVKSTAPAATSSRSAAFAAYYKIQDSPFSINNLVETGAFCSGGSYLLTIDNPGSGENDSPLNYPSLTYNWFKETGPTTSVFVAEGNTLNVTQEGTYFVKTNYGTCTSSSFSNRVSISEAVSGEASASITSSLGSPFCPDQGMTTLSTISGLGYQWFKDGVAIPDAIEQTYQTDASGLFAVQVDLGSCQASGAIDLVSESFEGSLNVSEVNEIEEGESLEVTVSTTAQNPTYVWYFNDTLIPGATSDTYTASAFGAYSVLVSQSAGCVATNTFPFEITEAMDPFPEVANIPNLISPNGDGINDTWVIPLQYVDGTDTEVMIMDNRGKIVLQTKAYLNNWPEDQLDLNSINQVYYYILTTPDNKTKKGSITLVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCC7</accession>
    <name>A0A5C6ZCC7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000045">
        <property type="protein sequence ID" value="TXD86644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0675">Receptor</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023141047" evidence="1">
        <location>
            <begin position="23"/>
            <end position="889"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="889" mass="102558" checksum="5000055267622986" modified="2019-11-13" version="1">MTKKIKFLWLITLLFFSFNGLAQIQGNVLDINKQPIEFVTVVLKKAVDSTFVTYTRTDSDGFYSLKSKTIGTFLLSFSSLGYAKKEQNIVVTDVSKTIKINITLQEEIVSLDEVVVRAELDITQKKDTITFNAKAFAQGNEEVVEDLLKKIPGLTVESDGTIKVGNQEVEKVMIEGDDFFERGYKLLTKNMPAQPIDKIELLQNYSNNRLLKGIEESERVALNLKLSDDAKRIWFGNMTIGYDAFANEDRYHIKGNLMNFGKKNKYYFLSNANNIGFDATGDINHLIRPIRFNEPASLGDNQSITSLINLAVNTPNFKRSRITFNNAEMASLNAIFNPTEKLKIKTLGFLNWDELDFFRNRVDNVSVNGLDFTNTEDYQLQNKKRIGFGKVDLIYNLSKTKMLEATSKYQNANFSSASDLVFNNQSTVENLNNPVELFDQKITFTNKFKENKVLLLTGRFIDETAPQNYSVNQFFFNDLFPNTTANNVNQNLVQKMTFAGIEAHLLDRKENKNLFEFKIGNTFRKDNLNSQFSLLENNTEISEPIGYQNNLSYSVNDLYLTTKYQYSLNKVKFIGNLSVHQLFNRLEQNNQSSSQQPFFINPSLGIDYKINGNNRIRTSYAHNRTNATVLNVYNDFVLTGFRNFNSGAGDFNQLDASAFLLSYQLGNWSDRFFANTTFSYTKNHNFFSTNTIINQNFTQEEAIIIKDREAFDTKASFDYFLKKLSSNIKINLGFTQSEFKNVVNNSELREVSSINYEYGIEFRSAFDSFFDFNIGTKWLNNEIKTTVTNEFTDNVSFLDLNFYVNDKFNMDLQTERYFFGNLQSDNTYYFLDFNARYTIKENKLTLMLSGKNLFNTDTFRNFTISDIGNSTTEYRLLPRYVLLKMEYRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCK9</accession>
    <name>A0A5C6ZCK9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Acylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_18945</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <text evidence="5">Binds 1 Ca(2+) ion per dimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S45 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000035">
        <property type="protein sequence ID" value="TXD86889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017000">
        <property type="term" value="P:antibiotic biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.439.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014395">
        <property type="entry name" value="Pen/GL7ACA/AHL_acylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043147">
        <property type="entry name" value="Penicillin_amidase_A-knob"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023343">
        <property type="entry name" value="Penicillin_amidase_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043146">
        <property type="entry name" value="Penicillin_amidase_N_B-knob"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002692">
        <property type="entry name" value="S45"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34218">
        <property type="entry name" value="PTHR34218"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01804">
        <property type="entry name" value="Penicil_amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001227">
        <property type="entry name" value="Pen_acylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0865">Zymogen</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023124413" evidence="6">
        <location>
            <begin position="23"/>
            <end position="693"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="249"/>
        </location>
        <ligand>
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR001227-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001227-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD86889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="693" mass="78172" checksum="93DF753671EF946F" modified="2019-11-13" version="1">MKNLFISSLLILSLILNGFSQNNPSTTIIWDTWGVPHIKSDNLEDLFFAQGWAEMHNHANHIIELFGVSRGRGAEYWGKDKLMDDMLIHTLGFSELADTWEKTQDPTTKKIYDSFVRGLNAYADAHPEAIEEANKKLLPLTSKDAKMHSMYIVFTRFIGGGDLGRVQEWPDMGSNAYAIGPSKSASGNAMLVQNPHLPWFGEFLFFETHFNLNGKNMYGANLVGLPGIAIGFNDHLGWSHTDNTIDNADTYELDLKDGGYLIDGERNDFEVSSKTIKIKQEDGTLIEQDIPIMKTRYGPVVKKSEDKVLAIRMVGMDRPDMALQWWKMINAATFDEFETALKMAQIPFWNVMYADDAGNIFYLFNGLVPKRSSGDWKYWNRFIPGGKSADLWTEVHSYSDLPKVKNPETGWLQNSNDPPWTSTLPMILKPSDFPSYMAPIYMSYRSQRAARMLMEDNSITFDELVDYKLSTHLEFADRILDDLQIAVENSNSDRAKVAMKVLNAWDREADNDSRGTLLFYNWARKFNLRKDGNYAQAWSFDSPGTTPDGISDPKNAVSSLENAANEIEAGFGKLDVAWGDYYRITYGDKDLPANGMDGALGTFRVAWPGRVDATHAYVGGGDSWVGVIEFGETPRAKVLLSYGNATQKDSPHFGDQLELFSKKELREAWFTDSEIEANTNYVEVLTGNTFVKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCM6</accession>
    <name>A0A5C6ZCM6_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Fructose-1,6-bisphosphatase class 1</fullName>
            <shortName evidence="7">FBPase class 1</shortName>
            <ecNumber evidence="7">3.1.3.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">fbp</name>
        <name evidence="11" type="ORF">ESY86_18775</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>beta-D-fructose 1,6-bisphosphate + H2O = beta-D-fructose 6-phosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:11064"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="EC" id="3.1.3.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="7">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 8">Belongs to the FBPase class 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.11" evidence="7"/>
    <dbReference type="EMBL" id="VORO01000034">
        <property type="protein sequence ID" value="TXD86915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042132">
        <property type="term" value="F:fructose 1,6-bisphosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016051">
        <property type="term" value="P:carbohydrate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00354">
        <property type="entry name" value="FBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01855">
        <property type="entry name" value="FBPase_class1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044015">
        <property type="entry name" value="FBPase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000146">
        <property type="entry name" value="FBPase_class-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033391">
        <property type="entry name" value="FBPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028343">
        <property type="entry name" value="FBPtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020548">
        <property type="entry name" value="Fructose_bisphosphatase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11556">
        <property type="entry name" value="PTHR11556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00316">
        <property type="entry name" value="FBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18913">
        <property type="entry name" value="FBPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500210">
        <property type="entry name" value="FBPtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000904">
        <property type="entry name" value="FBPtase_SBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00115">
        <property type="entry name" value="F16BPHPHTASE"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00124">
        <property type="entry name" value="FBPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 8" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FBPase" evidence="9">
        <location>
            <begin position="6"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="domain" description="FBPase_C" evidence="10">
        <location>
            <begin position="204"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="120"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="262"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="117"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="274"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="280"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF18913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD86915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="339" mass="38000" checksum="BC5594C517E75382" modified="2019-11-13" version="1">MVTQTKTLGEFIIENQEYFKYSSGELSRLINSIRLAAKVVNHEVNKAGLVDIIGAAGDTNIQGEHQQKLDVYANTKFIQTMTKRNIVCGIASEEEDDFIAVNSQDENHQNKYVVLIDPLDGSSNIDVNVSVGTIFSIYRRVTPVGTPVTIADFLQKGNQQVAAGYIVYGTSTMLVYTTGHGVNGFTLNPAIGTFYLSHPDMQFPEDGKIYSVNEGNYIHFPQGIKNYIKYCQMEEGDRPYTSRYIGSLVSDFHRNMIKGGIYLYPKSSKMYEGKLRLLYECNPLAYIAEQANGKASDGFTRILDIEPTELHQRVPFICGSKNMVEKAEEFMKDARNLNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD25</accession>
    <name>A0A5C6ZD25_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Acyl-CoA dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_15650</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00072">
        <property type="entry name" value="ACYL_COA_DH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="8">
        <location>
            <begin position="6"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="122"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="229"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD87747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="380" mass="41740" checksum="F4038756A793B638" modified="2019-11-13" version="1">MDFSLTEEHKMVRDAAREFAQNELLPGVIERDEKQKFPKDLVKKMGELGFMGIMVDPKYGGSGMDAISYVLVMEELSKIDASASVIVSVNNSLVCYGLETYGNEEQKQKYLTKLATGEFVGAFCLSEPEAGSDATSQRTTAIDRGDHYVINGTKNWITSGGRADVYLVIAQTDKHKGSHGINAFILEKGMAGFDVGPKENKLGIRGSDTHTLQFNDVKVPKENRIGEDGAGFLFAMKTLSGGRIGIAAQALGIAAGAYELALKYSKERKAFGTEICNHQAIAFKLADMYVEIEAARHLVMKSAWDKDQGNNYDMSSAMAKLYASKVAMEQTVEAVQIHGGNGFVKDYHVERLMRDAKITQIYEGTSEIQKIVISRSLIKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD37</accession>
    <name>A0A5C6ZD37_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_15765</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036440">
        <property type="entry name" value="Peptidase_C15-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53182">
        <property type="entry name" value="SSF53182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1066" mass="119318" checksum="47ADF43145EC2418" modified="2019-11-13" version="1">MSFYFFTEPLKLTNQTEYQSFGAIDENNYRLGNMFSISSDAKAFAITDGLILVQQIGTTDRYNIILKPSVEPDLNLPKISYIIYKGIKKSSLISGDKVAAPINNDLTKFIHASAEQWYAADGVPVPDTEPAASTSLGLEYSASNPDTEFTTEDPDELDKVFYSSDSLTLPFAFASNYIGDFDSSGDIGLTIIFEKIGYRPTFKIARELDSIMTFDPLSGSPTQAESFALKDKKEVVLSYIDSSAFFGAFNGLGLKVFNGTGFTNKNGDALFNDVISKHFNKNSIYLDIRNESNDSFNYLENYGDTIKLSLDNSTTFIPLDYTRNNKWPILLINDTAPDSEFSENNTNKIIKVNLPRGDNEIPLVYYKRAFKNDLGLVLPDGKKQFLTPAIEDEETSFEEIIPYVTNGSANSNYFQLRYIRRVRNNENPINNFPTKGFSIFQNGYLDGLFPIFDMAIPFEQDSGKSYSKIYYDVKFIDKANINGNQFTANLGIGKDSVYTTFISYPSNYNLNIRQNNDDKIPLSGFEGPVSSLFLLELNNQIQSIKIVKSEFKINGSVQEYIRFENQTTFSDTETENYTFEDVSILALTNQEFQDLEQLKNQEFPVDYKVNLGVTNIEVGTDDEGKAYTKFEYVLRGLKEDGSGNIVRHSASPSPAMVVYTDEKVLGSEYVRNYEEAIGYDNFQDAAAGLRYEDFFINKQPGIKRVVDDFINELYNSESSSTLFFDAIKSLVSITGKTLWNTAVNSVQANLNSPDDRPLYWARLKIAVFIKQHPLFKGDIDVNSRVIEDSDLSQIISLFEETSRNYTGVNFSSAGTAKKILVVGFDPFFLDENNPVLSGSSNILHSNPSGISVLSMNSINTANGIGYIQSMIVPVRYTDFDSDLNPSMGEGKGIIENYIGKLLNNVDMIITLSRDGAPSDYNIDKYATQNRVGNVPCNLNFVREPDSDSITDTSKWIESNLPNELVLSPEVEFDFTYVDSTGITKDGSVDEPDPNEKMTRGSGGSYLSNEIFYRVARLREMISIDKPKTGHFHVSKFQEANEDLIFSRAKALVDIVKKAIDDGATGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD82</accession>
    <name>A0A5C6ZD82_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Probable nicotinate-nucleotide adenylyltransferase</fullName>
            <ecNumber evidence="6">2.7.7.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Deamido-NAD(+) diphosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Deamido-NAD(+) pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Nicotinate mononucleotide adenylyltransferase</fullName>
            <shortName evidence="6">NaMN adenylyltransferase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">nadD</name>
        <name evidence="8" type="ORF">ESY86_15285</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 6">Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>ATP + H(+) + nicotinate beta-D-ribonucleotide = deamido-NAD(+) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22860"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57502"/>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
            <dbReference type="EC" id="2.7.7.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 6">Cofactor biosynthesis; NAD(+) biosynthesis; deamido-NAD(+) from nicotinate D-ribonucleotide: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the NadD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.18" evidence="6"/>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00332"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004515">
        <property type="term" value="F:nicotinate-nucleotide adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02165">
        <property type="entry name" value="NMNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00244">
        <property type="entry name" value="NaMN_adenylyltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005248">
        <property type="entry name" value="NadD/NMNAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00482">
        <property type="entry name" value="TIGR00482"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4 6" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CTP_transf_like" evidence="7">
        <location>
            <begin position="5"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD87835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="192" mass="22907" checksum="FA50E52C3F28A1E8" modified="2019-11-13" version="1">MKIGLFFGTFNPIHVGHLTIANHLAEYSDLEKVWFVVTPHNPFKKKKSLLDNRQRYEMVYQATKDYLKLEPCDIEFNLPQPNYTINTLVHLKEKYPQHEFSLIMGEDNLKNFHKWKNYELILEQYELYVYPRISEGSIETQFTGHNRIHKIDAPIMELSSTFIRKGIKAGKNVRPMLPEHVWAYLDEMLFYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDB8</accession>
    <name>A0A5C6ZDB8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">T9SS type A sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_15525</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022995073" evidence="2">
        <location>
            <begin position="27"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="domain" description="Por_Secre_tail" evidence="3">
        <location>
            <begin position="654"/>
            <end position="729"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD87875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="733" mass="78226" checksum="67E465BE4AB10351" modified="2019-11-13" version="1">MKTKITKVLRSWCLLPLLLMSLIVQGRENSAIEIALGINDVTLISGVENFSISFEKERIWEVSPASISDLGGHEGDDNGPKITICHYPPGNPENVQTIEIAASAWPAHEAHGDTQGACSNDDDDDEGDDDDEDEEGCYAMEVIDYSPTVQSNGNAIANNRTDATVTLGEPDRANEAGGFASLGIGGQLTLRFSGAVYDTAGDDILIYETSFSGDNCSGANDERAMVEVSQDGTNWYDAGEICRDGAIDLDGIPVVYVTHIRITDITTGSGDGYDVDGVEAVNGCQDVPSDENDPCYGAFVVDNSYMPGLKKNGQPITDPERLDPSKALGVPQVDNTSNFVSLGYGGEITIGFDGLVLNQVGDDLVVVETTYGNATFASYPESADVYVSQDGFNFYFIGSVLTNESASLDISNASVALSYITQVRVVDTTPEGSVSPDGFDLDGIISLPGCTVLEDPNTCFSEIVNGGFEDDNTFAGSWKYVPQDEVPGWSTTSPTGTIEIQRSGMVDGNASNSGGFHFELNGDALNNIYQEICTTPGSNIEVSFSYMKRRNSGVDEMELYFSDAIETITDGTAYPFMATPGAGWETKSFVYAVPAGQESTIIFFKAVSGTSATIGNLLDDISVATTLASPTSLEELFAALSTKDQVLATTEVTMYPVPARDRLNVKLRSQLGGKVSYEIVSIMGQSLGRGSLDNYSGQGEIHADVSNLADGAYFLMIHLNGETISKKFIKATR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDI2</accession>
    <name>A0A5C6ZDI2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Polysaccharide deacetylase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_14310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51677">
        <property type="entry name" value="NODB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NodB homology" evidence="1">
        <location>
            <begin position="28"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="261" mass="29777" checksum="9EDD804C36708A45" modified="2019-11-13" version="1">MKLIPVKTPWLFRKIFPNYVWNVKTDEKIIYLTFDDGPTPEVTDFVLDTLNAHQAKATFFCIGNNVEKHPKLFQRILAEGHRVGNHTQNHTKGWETTTAAYLQDVAAAEGIIQDSKFKVQGLGFEVQDSGFNTEISRQNSKAKNTSKVSLEDLGDNQQSSIDNLQSSIPKLFRPPYGLIKPAQSKQLMQLAYKIVMWDVISFDWEQELSEEKCLQNVISNTESGSIIVFHDSIKASKNMMYALPRMLAYFSEKGFRFESLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDP2</accession>
    <name>A0A5C6ZDP2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">T9SS type A sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_16000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000021">
        <property type="protein sequence ID" value="TXD87661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Por_Secre_tail" evidence="1">
        <location>
            <begin position="350"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="420" mass="44867" checksum="15AB88CE004936AF" modified="2019-11-13" version="1">MTFANIENPDPTGINTSARVLQVDKPSGADAGGGFGFEAPSFTGIDLANGTVFTLKIWSTKANLQLRFQMQTGAPTYQRDVIVADAGVWTEVTFNFTGQTGLTGTEQYSVLVIQPDLDPPCGGNPCPPIEVSGTYYIDDITQSEASEPTCNDGIQNGDEEGIDCGGSCPDACDTGDNTVSDFLVDFETPSDFTGGDLTVTEVTNDNPDAVNSSATVLQVENINVAPFANAQFLLSNNSVLDLSTNDRGFALKVRGPRAIPILFKAEDAGNGGINREVPGNYTDVGNWQTVFFDFSAFADPTTLGRIVIFFDITGAPSADGADDLFYIDDVKFGEFTTLSSNQFVASDFKVFPNPTNNAWTIKAKKELTQVQVFDVLGKSVMTLNPNALNVELDASTLNRGIYFAKISTVSGSESVKLIKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE04</accession>
    <name>A0A5C6ZE04_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Site-specific integrase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_15700</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035386">
        <property type="entry name" value="Arm-DNA-bind_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025269">
        <property type="entry name" value="SAM-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17293">
        <property type="entry name" value="Arm-DNA-bind_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13102">
        <property type="entry name" value="Phage_int_SAM_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="3">
        <location>
            <begin position="220"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD87755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="409" mass="47124" checksum="F49C506F1C94C72B" modified="2019-11-13" version="1">MSFAISILFHIRKTKTDSNDLANIYCRITVDGTRSEMSISRKIPVTKWDAAAERVRGTSVKAQEINSLIRSIENFFFENHQELSKSGQSFTAKDLRDKYHGKNQIYKLALELFREHNNKILRLIPAGDYALGTYKRYDTVCNHLENYIISSYSIPDIPIKDVDYKFIEGFAFYLKTEKNCANNTALKYIRNFKKVIHIAQAHGYIQIDPFINWKMKKKVVNREILSDAEIKRLAEKDFEMNRLNQVRDIFIFACFTGLAYIDVQKINQDDIFLGDDGGQWIKIKRTKTDTPSSIPILAEAQRILDKYANYSRVENDNRLLPVASNQKVNAYLKEIAVICQIKKTLTFHMARHTFATTVTLSRGVPIETVSKMLGHTNLTTTQHYAKVLDLKISKDMQALKEKGSLLIDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE53</accession>
    <name>A0A5C6ZE53_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Metallophosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_14300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="Metallophos" evidence="2">
        <location>
            <begin position="162"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="409" mass="46545" checksum="86E803C17D2176E5" modified="2019-11-13" version="1">MLRWILFVSIYILLSIYGFQAIKTLTKVTWIHYLFLGISLVVVGNFIYQFSIGSEGRVLNPAKSYAFGFLLAFMALNLILVPFLLGEDIIRAAIGIFEKRVTSEEGFHLPSRRKFISGLALGLAAIPFAGLLYGMYKGKYRFRVLDYTLHFEDLPEAFDGYRITQISDIHSGSFDNHKKIQYGVDLIKAQKSDVILFTGDMVNNKTTEMLPWVDMFSQLKAPDGVYSVLGNHDYGDYIDWPSPAAKAQNIADLVQLQKDLGFDILLNESRFIERDGQRIAIMGVENWGKGGFKKAGDLQKTKENVASNDFKILMTHDPSHWEEEVLPDDYHFHLTLSGHTHGMQFGIEIPGWIKWSPIKWRYKQWAGIYKELGQYINVNRGFGYLGYPGRVGIWPEVSVITLKKGTKEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEA4</accession>
    <name>A0A5C6ZEA4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_18410</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000031">
        <property type="protein sequence ID" value="TXD87047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010559">
        <property type="entry name" value="Sig_transdc_His_kin_internal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06580">
        <property type="entry name" value="His_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="396"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="158"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="198"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="318"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="domain" description="His_kinase" evidence="3">
        <location>
            <begin position="430"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD87047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="646" mass="74002" checksum="4424FB1E405DCA84" modified="2019-11-13" version="1">MLLCGLMCPLGSGAQDDKDQNTVFKTAVDQLLANTPRDYTSINDVLYPYRGDSIKLKQFISKAKNENYLEGESYALNVLGVLYRNISQYERSIKLHKKARELAQVADNVELRVISLNNVGVAYRRMNLVKPALDFHTKALDISSALKNPSQEIQHNIAVSHNSIGNIYLVLEQYDLAMKQFQKSLIIEKKEGNQLGLAINYQNIGYAYEQKGDLENALRNYKLSLDFNNQINSNLGRVICYNSIGAVYIKQKKYIDAKMIIEKALEKVLIIGDQFYVAESYINLGWVQEEMGQLEASERNLNKGLNIAKAHNLNFYIVEAGKHLSDLYAKKGNYELALQHFTEAITIEKNINNDRNLRYVNDVIIQYENEVKNREIKALANENELVKFKLERNKTIFWYSILGLAIIAASLIAVYRNRQLQQEKQILTLEQDMLRNQMNPHFIFNSLNSIKLYIINNEKENAVYYLNKFSKLIRKILVASTEKETTLADELDTMQLYMTIENIRFDDQILFNIKVEDTINTASIKIPSLILQPFLENALWHGLSSKADDKKIKLHVYRTSEDMVDIAITDNGIGRKEAAKIKSGKYLKRKSMGIAITKARLANFSKSYTEDYQINIEDLYDNSGNKAIGTRILVRIPTRTTAMRTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEB3</accession>
    <name>A0A5C6ZEB3_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminotransferase</fullName>
            <ecNumber evidence="1">2.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_16570</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.-" evidence="1"/>
    <dbReference type="EMBL" id="VORO01000023">
        <property type="protein sequence ID" value="TXD87508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="2">
        <location>
            <begin position="32"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="395" mass="43660" checksum="A31A2F7E7A901E86" modified="2019-11-13" version="1">MTQLSERVLNMATSATLAMAAKTRELKEEGKDIIGLSLGEPDFNTPDYIKEAAKQAIDDNYNGYTPVDGYTELKDAIITKFKRDNQLNYKRSQIVVSTGAKQSLANIAAVLLNKGDEVILPCPYWVSYSDIVALNEGVPVEVKTAIENDFKLTPEQLKAAITPKTKMIWYSSPCNPSGSVYSKAELRALADVLKDYPEIIIVSDEIYEHINYLGGGHESMAQFEDMYDRTVTVNGVSKAFAMTGWRIGYIGASEQIAKACTKMQGQITSGANCIAQRATITALNESPSKIQFMVDQFKERRDLILDLLNEVEGFKTNVPEGAFYVFPDISYYFGKTIKGQTINNAEELSLFLLEHALVATVTGEAFGSPNCIRLSYAASKEQIIEAIKRIKEALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZED5</accession>
    <name>A0A5C6ZED5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Rhomboid family intramembrane serine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_14780</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="SSF144091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="67"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="92"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="114"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="139"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="Rhomboid" evidence="6">
        <location>
            <begin position="51"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD87931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="255" mass="29906" checksum="05411B6BCC59AC7D" modified="2019-11-13" version="1">MEQQAQFRYSTSVILYPLIFVLSIWMVFWLQVRFFPSIKHMGIRPQEWQGLFGIFTSPFIHADIEHLFHNSLPLFILSVALFYFYRNISWKVLVYGILLSGLITWLIGRPSNHIGASGLVYVLVSFIFFKGIFARYFRLVALSLVIIFLYGSLIWYVFPVKEGMSWEGHLGGLITGLLFALIFRKSVAKPERYVWQEPDYIEDDDPFLRHFDADGNFIENLEPEKPEIEIESEAKIEETQISLKVNYIFKENPDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZER4</accession>
    <name>A0A5C6ZER4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">M23 family metallopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_17660</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000027">
        <property type="protein sequence ID" value="TXD87261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022886729" evidence="1">
        <location>
            <begin position="23"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M23" evidence="2">
        <location>
            <begin position="195"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="371" mass="41528" checksum="872143B196D81359" modified="2019-11-13" version="1">MKWNIKLLLILFVFASCTQVQKLSDAITNPSARDLFERDLKPEDSLYRHYEITYSEAKQNALRLDLPSAVSTKTDSASIKILAYTLELKRGERFKVFTKNEADSLQLLIDVYAFENDSVVSKKPLFSNMPNENALEFEVIKNGRYKLVIVSRIQKMRDYVMIIFTEPTYLFPVSGKENSAIQSFWGASRSGGARSHEGVDIFAERGTAVIAASDGYVSSVGNRGLGGEQVWLRDRRFGQSQYYAHLDSIAVKSGAKVRLGDTLGFVGNTGNARTTSPHLHYGIYTFAGAIDPLPFIARKTIPENDFQQLPQIGSTKLRVNELRTGAGVKNEKITDLKGEKPLVILAQTGQWYHARVNDSLEGFIHESLVKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEV4</accession>
    <name>A0A5C6ZEV4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">J domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12570</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="SSF46565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="SSF49493"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="1">
        <location>
            <begin position="5"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="299" mass="33776" checksum="A73AEF4BE6B54F29" modified="2019-11-13" version="1">MAFIDYYKILGLDKGASTAEIKKAYRKQARKYHPDLNPNDKEAEVKFKQVNEANEVLSNAEHRKKYDKYGENWKHGDAYAQAEQQQRQQQGSRQYAGNAQGFEGFGDGEYSDFFESMFGGGFSNRGSNVKYRGQDFNAQLQLNLKDVYTAEKRVLTVNGKNIRLTIPAGITNGQIIRIKGKGGAGQNGGPHGDLLIEFQILNNTDFKRDGANLYKDVELDLYKAVLGGELTVNTFDGKAKLNIKPLTQNDTKVKLKGKGFPKYKKENQHGDLYINFKVQMPKKLNDKEKALFEELAKLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEW1</accession>
    <name>A0A5C6ZEW1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Glutamine--tRNA ligase/YqeY domain fusion protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ESY86_12665</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004819">
        <property type="term" value="F:glutamine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006425">
        <property type="term" value="P:glutaminyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.240.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004514">
        <property type="entry name" value="Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020058">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020059">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_codon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020061">
        <property type="entry name" value="Glu_tRNA_lig_a-bdl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020056">
        <property type="entry name" value="Rbsml_L25/Gln-tRNA_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011035">
        <property type="entry name" value="Ribosomal_L25/Gln-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00749">
        <property type="entry name" value="tRNA-synt_1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03950">
        <property type="entry name" value="tRNA-synt_1c_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50715">
        <property type="entry name" value="SSF50715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00440">
        <property type="entry name" value="glnS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 6 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1c" evidence="8">
        <location>
            <begin position="27"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-synt_1c_C" evidence="9">
        <location>
            <begin position="345"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="126"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="549"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="552"/>
            <end position="571"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF03950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD88367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="669" mass="77279" checksum="FBDDAFDDB72572DA" modified="2019-11-13" version="1">MSEEPKSLNFIEHIIEEDLKAGLSKDKLRFRFPPEPNGYLHIGHTKAIGISFGLGEKYNAPVNLRFDDTNPAKEEQEYVDAIKRDIAWMGYEWANELYSSDYFQTLFDWTIQLIKDGKAYVDSQSSEAMATQKGTPTEPGVDGPYRNRTVDENLELFLSMKAGKFDEGKHILRAKIDMQHPNMLMRDPIMYRVLKKEHHRTKANWCIYPMYDWTHGESDYIEQISHSLCSLEFKPHRELYDWFKEHVYQYASNELPMQPKQREFARLNLSYTIMSKRKLLQLVQNGVVSGWDDPRMPTISGLRRRGYTPKSIRQFIDKVGVAKRENVIDVSLLEFCIREDLNYSAPRVMAVLDPVKLIITNYPDGKEEWLEAENNQEDDSAGFRKVPFSKALYIERDDFKEEASSNFFRLKLGGQVRLKNAYIIKGETVVKDSNGNITEIHCTYSTDTEQKVKGTLHWVSIKHAIKVEVREYDRLFRDEAPDSHPETDFMEFLNPNSLKIIEAFVEPSLAEAKVGERFQFQRLGYFNVDDDSTEDLLVFNKTVGLRDSWAKQKPKPQQQQNTPQAQQQQKRPAIDEIKKLGKKYANLPEDKQQKTKTVILKLAEDVSYDEVQDLFNTSVKKTGTRIATVLMLSVLLKNGQERNTEIEEFLASAKADSNTTLVVEANAVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF10</accession>
    <name>A0A5C6ZF10_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF3098 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_13880</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021448">
        <property type="entry name" value="DUF3098"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11297">
        <property type="entry name" value="DUF3098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="89" mass="9893" checksum="E9FEE6ED3A104C8B" modified="2019-11-13" version="1">MGEQKRKETLKNDFIFGAKNYKFMLIGLGCIALGFALMAGGGSDDPNVFNPEIFNWRRIRLAPTLVLLGFGIQVYAILLNPNKDADSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFC1</accession>
    <name>A0A5C6ZFC1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MarR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01047">
        <property type="entry name" value="MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="145" mass="16528" checksum="CE6DBDDF1545BE01" modified="2019-11-13" version="1">MGDLAKDIHSRFTSHRVKALLNILYTANWISSAQTSYLKSYGISPQQYNILRILRGSAEPLKVQTIKDRMIERSPNTTRLMDKLCAKQLISRIASEADRRVVKIKLTNKGDELLTSIPSDLNQELLKNLSEIEAEQLSTLLDKMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFD0</accession>
    <name>A0A5C6ZFD0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">SLC13 family permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_13525</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004680">
        <property type="entry name" value="Cit_transptr-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031312">
        <property type="entry name" value="Na/sul_symport_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03600">
        <property type="entry name" value="CitMHS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02080">
        <property type="entry name" value="TrkA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01271">
        <property type="entry name" value="NA_SULFATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="25"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="91"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="132"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="169"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="418"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="467"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="497"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="529"/>
            <end position="547"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="553"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="590"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="8">
        <location>
            <begin position="317"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD88318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="612" mass="66120" checksum="5BA9465D122DC373" modified="2019-11-13" version="1">MVVLLVILFITIALFIWGKFPPDVVALMSMIALFLSGILDLSETLSGFSNPTVLMIAALFIIGEGLSRTGWTALAGQKFVAWAGKSVPKLLVLITLGSGVLSGFVSNTGTVAALLPVTVSAAWKAGTVPSKLLMPVAFGSNTGGLLTLTGTPPNIIVSNTLTEKGMESFSFFEFGLIGLPLLIIAILYFKYIGYRLLPNHKTQNQPVNIDSEVHKWISNYSIGNNMYRLRIRSMSQLIGTKIGDWEFEQKHNVSVMRLRRRHPSILKATPQFVELPQPDTEMRYHDIITVKGSATDVDKMILEFQLGLIPRDFKPSEIKKEFINQEIGMAEMIVTPTSFFVGRTLPLGKYLQKSGIQLLGASRDGKPLADKNITIKAGDAFVIRGSWKNIEALHEVYENLVISGSPEAMAKDVDDITIKSYIALGTLLLMIVLLVFEILPGAIAALICAGIMMLSGCVPIKKAYTGISWTSVVMIAAMIPMGIALQKTGTAELVSNGLVSTLGSIHPIMLLGGIFLTTTIFSQTINNSATAVLMAPIAFMAAVSLGVSPEPFMIVVAISASTAFLTPVGTTTNAMVMGSGGYKFIDYVKVGAPLLLLFFVITMLVVPVFWPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFJ3</accession>
    <name>A0A5C6ZFJ3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lactate utilization protein B/C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15095</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024185">
        <property type="entry name" value="FTHF_cligase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003741">
        <property type="entry name" value="LUD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02589">
        <property type="entry name" value="LUD_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LUD_dom" evidence="1">
        <location>
            <begin position="36"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="203" mass="23577" checksum="1247C307B40BFF8C" modified="2019-11-13" version="1">MSLFRKIFGLKNTPEETIKNEERGKYMPEVKLPIDEQFTINFKANGGKFLYCENMQEIQQNLKFILSENNWQNEKVFIYDEQLNQLFKAMDFDATKKVSESTYFFSTCEYLIADDGSLLISSNQIAEKKLKELPDHLIIFATTSQFVQNIGEGLRGIKHKSKQNSKIPTNITTIKHFKTIEDKDFLSYGSSSKNLYLLLLEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFP0</accession>
    <name>A0A5C6ZFP0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SH3 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_13080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022757186" evidence="1">
        <location>
            <begin position="39"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="246" mass="27250" checksum="36DED5E0AF46B355" modified="2019-11-13" version="1">MKTLKNSTATVETLITPTKILKSCLAIAILLMASFSFAQEEVEFDVYSNSAEKASQYLMGDDVALRDCASAHCEQLTTITIGTNVRLLAKSETAQTINGVKSRWYKIKMGPQIGWIWGGLISQKTLVSHVNPEVKFVFGEAGLDYKGYKRFQMRAVKNGVEIDKIFIKSDSLHFSKVRLLDSDTVGNKDVISLGDSTNEDTAINATAKYILFKNDKFEQASSFLTATQAEYENANYAYACGFEAQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFR2</accession>
    <name>A0A5C6ZFR2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Metal-dependent hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15965</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000021">
        <property type="protein sequence ID" value="TXD87655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007404">
        <property type="entry name" value="YdjM-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04307">
        <property type="entry name" value="YdjM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="156"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="332" mass="38017" checksum="66DF389FDA6FD6E9" modified="2019-11-13" version="1">MDSLTQIVLGAAVGEAVLGRKVGNKAILYGAIAGTIPDLDIFASYFTDTVNALAIHRGFTHSIVFSLVFAPIFGWLVSRYETYKSFKDWSWLFFWAFFTHPILDAHTTWGTQLFWPLDLRLAFKTIFVVDPLYTVPFLIFLILCMFQRRDSKKRRLYNNLGLIISSTYLALTFLLKGLAFTQFEAALKDQNIAYRQIDTRPSPLNTILWSANVETADAYLIGNYSFFDSQAIRFESYPKNRELLGDLIKHPKVQQMIGISEGWFTISQIEGKLYYNDLRFGLLSLQPGSQKFVFRYEINQNDSGEVTFEEAPKSGRDGKQLIIDLWARIKGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFT7</accession>
    <name>A0A5C6ZFT7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">M23 family metallopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_12315</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M23" evidence="2">
        <location>
            <begin position="200"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="323" mass="37201" checksum="7CB94063128DFEB8" modified="2019-11-13" version="1">MAKVKYYYDPETLSYRKIERKKRKTLQYAMIFLLGSALFGFLFVFIASQFVQSPRERALKRELSNLQLQYDILDKHVDDAFAALENVEDRDNNIYRLYFEANPIPNEQRRAGFGGVNRYRKYEGYDNSKLIIESNKRLDLLQKAIVVQSKSLDEIAVLAADKEKFLSSIPAIQPVKNEDLKRMASGYGYRTDPFTKVRKFHFGMDFTAPRGTPIYATGDGEVIRADNRSTGYGNHIRIDHGYGYQSLYGHLFKYNVKANQKVKRGDLIGFVGSTGRSEAPHLHYEVFKDGERINPINFYYGNLSAEEYALLLEKASLENQSLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG46</accession>
    <name>A0A5C6ZG46_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_09765</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03220">
        <property type="entry name" value="ABC_KpsT_Wzt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10147">
        <property type="entry name" value="Wzt_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015860">
        <property type="entry name" value="ABC_transpr_TagH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029439">
        <property type="entry name" value="Wzt_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14524">
        <property type="entry name" value="Wzt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="45"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="82"/>
            <end position="89"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD89052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="426" mass="46846" checksum="7885369704231B3E" modified="2019-11-13" version="1">MSKDAIIKVENLGKQYRLGSVGTGTLSHDINRWWQKVRGKEDPYLKIGDVNDRTSTGGSDYVWALKDVNFEVQAGEILGIIGKNGAGKSTLLKLLSRVTAPTTGMITCHGRIASLLEVGTGFHPELTGRENIYLNGAILGMTKKEIANKFDEIVDFAGCAKYIETPVKRYSSGMYVRLAFAVAAHLEPDILVVEEVLAVGDAEFQKKAIGKMKQVSEGQGRTVLFVSHNMASIQNLCNRVMVLENGTTVFRGDVASGIDFYMNANLKKSSIALVDREDRAGKKGVQFQDITIMDGKGEAIAEAFSGKPLYVDVTVKINRKLEQPIFRIMFIDTKGVIRFLCNNQFSMKSKMNLIDSGNQIIRCIIPEFPLPKGIYSVQLTCYSLEGVEDDIEAAMELTVAGGDFFNTGKEQVLKEGVLVKNTFEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG78</accession>
    <name>A0A5C6ZG78_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4350 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15945</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000021">
        <property type="protein sequence ID" value="TXD87652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="268"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="398" mass="46146" checksum="04984032B6FDF492" modified="2019-11-13" version="1">MSKTLKIYLALLCFLFIAIIAVEFSAPTPINWQKTYNETQKIPYGTFVYFNELNSLFPDSKVQEVKVSPYEYFDDYYSWADSSYLTTGTYISIDENNGIDDTSAQELLDFASHGNDIFISSSYFPPKFQDSLNFHLQNGYDFKGKAELSFTNPRLKSDSISAEKGLSNIYFSEIDTLKTTVLGYQKFGDSSYVNFTRTPWGEGAIILHAQPIVFTNYYMLKKKNAKYAAGVMSYLSDDTIYFDSKSKLVNVLGNSPLRFVLNNPPLRWAWYLALISTLLFMIFNAKRKQRIVRVIEPVKNTTVEFTKTIGNLYYETKDHDNLIEKKITYFLEYIRRVYFLDTEYLDEKFIKNLAQKSGKEYIDVKKLINQIAYLRSKASCNEADLLRLNSAIEHFYTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGC3</accession>
    <name>A0A5C6ZGC3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_13595</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.101.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036366">
        <property type="entry name" value="PGBDSf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="SSF47090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="417" mass="47807" checksum="BA3A888EB27F43A5" modified="2019-11-13" version="1">MSTLKLGLHDTGKAPSNPKEFLNILHAGDIKDVSSFKDEDRSTTLKFQAVSGSEITELQTFLYNAGFMPRGQYESVINGIFDYSTQASLRLFQEYVRTLDPEGDKNMKPDGIKGSGTQKHIDRWKLQNIKADWVNTSADQPSEEYSKWIGVLIAAKNHYLNNMNDILIEVEEFRKDTDTRKVSNWDYSTDEIHLVGIRRNQEKDDKIRRNDDLFILLINGMVFKFWGSTDPSQAMAYNDKKKRGRFDEPFLVEGQHKYRFGWHKSTYRALKPYKYGVLVFRDRDNDNALTESDIQKGLDPTPNGTINIHWSGVGSYNFSAGCQVIAGESYINHHNLNIDCSSFAGRNKSRLTNEFKETKGAYNVLADLVVCFSKPSKLGEKNHLYYTLGREKSFGLEEKFGKDYVIKTLRKMKSDIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGT0</accession>
    <name>A0A5C6ZGT0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NERD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011528">
        <property type="entry name" value="NERD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08378">
        <property type="entry name" value="NERD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50965">
        <property type="entry name" value="NERD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NERD" evidence="1">
        <location>
            <begin position="35"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="212" mass="24510" checksum="CDAB750F785D01F4" modified="2019-11-13" version="1">MIVWTIFALIACGLAVYIFGIRDYQDFRKVTSPSRGSRTERALVYKLLKYGIPYQTIFQDLSLKKYNGTYAQIDLVVATKVGLIVFEVKKYSGWIFGSGNQNQWTQVLNYGKIKHRIYNPILQNKNHIHQLKKKLSKENIPFFSVIVFYGDCELKNINYIPNGTYLVKSNKVFFVLRKILKDNKPATFTNKRELVSILNEAVMNGADYGIKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH25</accession>
    <name>A0A5C6ZH25_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_09545</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="61" mass="6950" checksum="5B5296CBF342DE72" modified="2019-11-13" version="1">MTTKLQTDSTDQLIYKNEILQLTVLGGIKLEGLDRMRITVKVQLQESSRPPVRPPLPLVYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH27</accession>
    <name>A0A5C6ZH27_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Gliding motility lipoprotein GldJ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">gldJ</name>
        <name evidence="3" type="ORF">ESY86_12620</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1580.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019865">
        <property type="entry name" value="Glid_motil-assoc_lipo_GldJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005532">
        <property type="entry name" value="SUMF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042095">
        <property type="entry name" value="SUMF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03781">
        <property type="entry name" value="FGE-sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="SSF56436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03524">
        <property type="entry name" value="GldJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022888088" evidence="1">
        <location>
            <begin position="23"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="domain" description="FGE-sulfatase" evidence="2">
        <location>
            <begin position="60"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="557" mass="63680" checksum="F45570B00EC675C7" modified="2019-11-13" version="1">MNMKHILNLRILLALMASLTIVGCSRNSSDGNSRATGWKINDKNGGFQYNDKFQEQEAGPGLVFIEGGTFTMGRVADDPMHDWNNAPSQQHVQSFYMDETEVTNKMYLEFLDWVKRTYPPEEENYRLIYHGVLPDTLVWRNRLGYAETMTENYLRHPGYGEYPVVGVSWIQAVEFANWRTDRVAEMTLQEAGYLERDSHLTSTGESNFNVDTYINAPTETYGGNDSIINPDRSRRRVQTTAAGDTINVYANRESGLISPDYRLPTEAEWEYAALGMSELRSFNVYRGRKKYPWDGQYTRSGARKTKGDQLANFKQGKGDYGGIAGWSDDGADITAQVMSYEPNPYGLYDMAGNVAEWVADVYRPIVDDEFNDFNYYRGNVYTKNAITEDGTVKIVTPEEIVYDTLSNGKVVARNLPGEILQVGVDENDTYLRTQFDQSDNRNFRDGDARSSRQYADSFEESEEDVITHKMYNSPLHNVERDSLGKIVKEYDESNQRTSLINDEVRVYKGGSWRDRAYWLDPAQRRYFPQDMATDYIGFRCAMSRVGSKTQGSGKKRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH70</accession>
    <name>A0A5C6ZH70_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_14095</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045944">
        <property type="entry name" value="DUF6364"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19891">
        <property type="entry name" value="DUF6364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="82" mass="9438" checksum="35D1A978A0410050" modified="2019-11-13" version="1">MDTKLTLKLNQEIIEKAKKYASDKKISLSRIVEFYLQALTTENKKDDFEISPFVKSISTGTSIPADLDHKKGYSDYLLEKHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHB6</accession>
    <name>A0A5C6ZHB6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Crp/Fnr family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_14165</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="193" mass="22984" checksum="451C707BE696BACE" modified="2019-11-13" version="1">MNIIEKTENIFEHFEKFIELSEKLKSELSQRIKPIEFKKGELVLDANHICTKSYFINKGILRTYFLKDGKEISEYFSGINEWVNSPKSFILRKKDIYYIDAIESTQAYFINVNDLVYLFDNFPEMERYARLSMGSVFGHFMERIISMRFTTAKEKYDHFRKTYSDIYHRIPLGMVASYLGITQETLSRIRAEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHJ6</accession>
    <name>A0A5C6ZHJ6_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Biosynthetic peptidoglycan transglycosylase</fullName>
            <ecNumber evidence="11">2.4.1.129</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Glycan polymerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Peptidoglycan glycosyltransferase MtgA</fullName>
            <shortName evidence="11">PGT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11 13" type="primary">mtgA</name>
        <name evidence="13" type="ORF">ESY86_12760</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>[GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate = [GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23708"/>
            <dbReference type="Rhea" id="RHEA-COMP:9602"/>
            <dbReference type="Rhea" id="RHEA-COMP:9603"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58405"/>
            <dbReference type="ChEBI" id="CHEBI:60033"/>
            <dbReference type="ChEBI" id="CHEBI:78435"/>
            <dbReference type="EC" id="2.4.1.129"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="11">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cell membrane</location>
            <topology evidence="11">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the glycosyltransferase 51 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.129" evidence="11"/>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009274">
        <property type="term" value="C:peptidoglycan-based cell wall"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016763">
        <property type="term" value="F:pentosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008955">
        <property type="term" value="F:peptidoglycan glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3810.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00766">
        <property type="entry name" value="PGT_MtgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001264">
        <property type="entry name" value="Glyco_trans_51"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036950">
        <property type="entry name" value="PBP_transglycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011812">
        <property type="entry name" value="Pep_trsgly"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30400">
        <property type="entry name" value="PTHR30400"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00912">
        <property type="entry name" value="Transgly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02070">
        <property type="entry name" value="mono_pep_trsgly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1 11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 11" id="KW-0133">Cell shape</keyword>
    <keyword evidence="10 11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3 11 13" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 11" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="Transgly" evidence="12">
        <location>
            <begin position="52"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TXD88384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="232" mass="26786" checksum="E6A9A6EFB30F8906" modified="2019-11-13" version="1">MIKRFFKLIFKILFWGFVASVFTVVVFKWLPVPITPLMVIRNTQATSTQKNRGWKHDWVPIENISTNLQLAVISSEDQLFVKHNGFDIEAIEKAYDNNQKGKKIRGASTISQQTAKNVFLWPSRSWLRKGLEAYFTFLIELIWSKERIMEVYLNSIEMGPGIYGAEAASQYWFKKSAAKLSRQEAAAIAAILPSPLRYRANPATAYIQGRKAWIVKQMYFYGPLNYENTDDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHL3</accession>
    <name>A0A5C6ZHL3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07480</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022763414" evidence="1">
        <location>
            <begin position="24"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="198" mass="22739" checksum="B7ED3723A0D912F6" modified="2019-11-13" version="1">MKNSLILILALMMSVSVASQAYKADIKKEAQTYYDHLTNKNFDAIFDYMYPKIFELASREQMRAGMEQMFNGKDMKIEFIANDVVSVTDTMEVKGVTYAAVFYNSKMRMTFLSEKDKPEAERKEFLKLMQSTMETQFGQANVISELENMALVINMDANMFAIKDPQYEGWKFIGNDDSMKPLVDSVIPETVRTGLMEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHV6</accession>
    <name>A0A5C6ZHV6_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Superoxide dismutase</fullName>
            <ecNumber evidence="2 6">1.15.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_08110</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2 H(+) + 2 superoxide = H2O2 + O2</text>
            <dbReference type="Rhea" id="RHEA:20696"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:18421"/>
            <dbReference type="EC" id="1.15.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the iron/manganese superoxide dismutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.15.1.1" evidence="2 6"/>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004784">
        <property type="term" value="F:superoxide dismutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.55.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001189">
        <property type="entry name" value="Mn/Fe_SOD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019833">
        <property type="entry name" value="Mn/Fe_SOD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019832">
        <property type="entry name" value="Mn/Fe_SOD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019831">
        <property type="entry name" value="Mn/Fe_SOD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036324">
        <property type="entry name" value="Mn/Fe_SOD_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036314">
        <property type="entry name" value="SOD_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02777">
        <property type="entry name" value="Sod_Fe_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00081">
        <property type="entry name" value="Sod_Fe_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000349">
        <property type="entry name" value="SODismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01703">
        <property type="entry name" value="MNSODISMTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46609">
        <property type="entry name" value="SSF46609"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54719">
        <property type="entry name" value="SSF54719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00088">
        <property type="entry name" value="SOD_MN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sod_Fe_N" evidence="7">
        <location>
            <begin position="3"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="Sod_Fe_C" evidence="8">
        <location>
            <begin position="93"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000349-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD89346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="202" mass="22914" checksum="BA86CE5F044E7AE4" modified="2019-11-13" version="1">MAFELPKLKYAYDALEPKIDARTMEIHYTKHHQGYTNKLNDAIKGTDHDGKSIENILSNLDMANTAVRNNGGGFYNHSLFWEVINPNDKGHLSGDLKEAIMDKYTSFEAFKAEFSKAAATQFGSGWAWLCVHEGGKVEICSTPNQDNSLMPGVGCGGHPILGLDVWEHAYYLNYQNRRPDYIDAFFDLINWNEVERRYAKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHZ7</accession>
    <name>A0A5C6ZHZ7_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF5689 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_08380</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043744">
        <property type="entry name" value="DUF5689"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18942">
        <property type="entry name" value="DUF5689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022761768" description="DUF5689 domain-containing protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5689" evidence="2">
        <location>
            <begin position="43"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="463" mass="50619" checksum="C23F4CB67FBDCB7C" modified="2019-11-13" version="1">MKTINLTQVLLLFLGMAVFNSCVQDDDFDTPDTSITEPQLDGNIVSIASVKGNVAQSGGLHLFEFENGPSDYMEGYVISSDEGSNFFEELVLQDKLENPTVGIKIMIDNSPLFTRYEVGRKVYVKLKDLSAVDDDGVLTLGIIPNANNIQKIPAFSETETLRRSSETGILVPMPLSISEFSDDKTNLWIRLDNVQFNRNLVINGNQTTFAAEIDDSFDAERRLESCNSNASTIFTTSTFADYKSLHLPSNSGSMNAILTKNFFGDAFNVTVNAPEDIFFDNDQRCDPNVLDCNGASGGGQDLYFENFEGFGSYTIEGWTNVNISGTNTNWLINGFGGNNYSRISAAFSGNQEADVWLVTPVIDLNVTTGEQLSFDIQASYDTGTNLTVLVTTNYTGDPTTTEWQPLDAIIPVGPSAAFGDFETIGPINISCLDGNINVGFFYEGSDPTATTRYHLDNIKVTGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI41</accession>
    <name>A0A5C6ZI41_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08675</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022858286" evidence="1">
        <location>
            <begin position="20"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="293" mass="33187" checksum="500AE76B6AACF27D" modified="2019-11-13" version="1">MKKLAFFFCFIVCSISLQAQETHLVDGESVELEIEANGKLDLLWKIINREYRYFVKTESNELIELKNTESNDGDFQYEYRTTLNQLTQDETLDTGAVNFTLSSLKAFVDAYNAASDNSYQSVPTEKRITTRLGVFGGITNSPFISNPDNLKSGLFGAELEVLDARGLMRSALFMQVRHVLEHDDLAYSTTEIALGYRFRVVNKRAFNLYVQTKFATLNFSDATIVSTDENDILTQNNIKETSFDIPLIFGIGVDIRVSENSFITLGYDQLFAILIDNQGNFSTDFTLGYKFNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI43</accession>
    <name>A0A5C6ZI43_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phytanoyl-CoA dioxygenase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_10145</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008775">
        <property type="entry name" value="Phytyl_CoA_dOase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05721">
        <property type="entry name" value="PhyH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="282" mass="32499" checksum="261A93E39A6F97F9" modified="2019-11-13" version="1">MHKTCELFLDGESYQFEVEGHFFWGENELLFKAEDNVISKMPWKGEGYAVVDAFSEAEFERLKASITKNITDAISESLPDFEPKNFKLEHYHKIVTSKELHNKVIDRTRNLENKDFDFDIDALAKRFGKILGYELTSWVEELQKSHIQIRLSRPNSLDINPPHRDGYLSYWENIINVWIPIVGCDKNSSLPVYPKSHLIPEHHILRTASKGAKINGNTYYVPCVLETKEGKIKMIRPNPSQGKALIFSPFLIHGAAVNKNEDVTRIALELRFPKVRNGLKMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI51</accession>
    <name>A0A5C6ZI51_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">M1 family metallopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10195</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022949418" evidence="1">
        <location>
            <begin position="21"/>
            <end position="945"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="945" mass="109722" checksum="84B5B5B6D806D55C" modified="2019-11-13" version="1">MKLKFALIITVFICSSVVGAQNRIDLKADFDVSKKTIQIAQKIRYENTSNDTLNFIYLNDWNSAYATKKTPLAERFTEEFNDKFHFAKSDQRGYTVLTVLKDSLGNSLDYSSEREHPDVIKVALQTPLAPNGFYELFLNYTVVVPDATFTGYGVDDLNNYHLKYWYLTPAVYDGAWQTYSNKNLDDLYIPPSDINLEISFPLEYQLISELDTEDIQQTILRQTYKLSGKQRVNTSLILSKFSEYKFVQTDDFTIVSNMATKGISIEEKALATDKITQFITENLGTYPHKRLLITKNDYKKDPLYGLNQLPDFIRPFPDRFQYELKLLKTALNNYLENTLLINPRKDYWLRDGVQIYYLMKYVEGFYPDTKLIGTLADIWGIRSFHAADLEYNDQFNLFYMQMVRTNRDQPLTMSKDSLIKFNANIANKYKAGIGLRYLDDFVNSEVVEGTISDFLKNNKVEITSSKKFENQLKKNTPKDVNWFFTDYVATSKKLDYKIQDLKKTKDSVTLTIHNKRDNSMPVSLFALNNDSILSKTWIENIDHKKTITIARDSIDRLALNFDNSIPELNLRDNYKSLKGFPFNNKPFQFRVIQDIEDPYYNQVFLMPLVEFNNIYDGLTLGAKFYNKTLLRKRLNYKLSPQYATKSKSLTGGGSVSFTHNVENTSLYYINYGFGGKYNAFAEDAFVTVFTPSLSFGFRNKDDFRSNESSYLNFRYLSISRTIGENAIIEDLDEPDYSVLNIRFVKSDPGLVNFSKWYYDVQFAQKFGKVAINYEYRKLSESNRQLNLRFFAGTFLYNNTDLSSNYFSFALDRPTDYLFDYNYLGRSEDSGIFSQQIIIAEGGFKSRLETPFANQWMVTGNASTTIWKYIEGYGDIGLVKSKGDNPAFVYDSGIKLDLVTDYFELYFPIYSNLGWEIGQPNYDQKIRIKFTLDPGALLGLFRRKWY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI70</accession>
    <name>A0A5C6ZI70_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Zinc metalloprotease</fullName>
            <ecNumber evidence="9">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">rseP</name>
        <name evidence="11" type="ORF">ESY86_07375</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the peptidase M50B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="9"/>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004387">
        <property type="entry name" value="Pept_M50_Zn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008915">
        <property type="entry name" value="Peptidase_M50"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42837">
        <property type="entry name" value="PTHR42837"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02163">
        <property type="entry name" value="Peptidase_M50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00054">
        <property type="entry name" value="TIGR00054"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 11" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="11" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6 9" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="103"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="371"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="416"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M50" evidence="10">
        <location>
            <begin position="10"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD89600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="441" mass="49886" checksum="E6B2F53F523DDE9D" modified="2019-11-13" version="1">MEFVIKISQFLLSLSLLIVLHELGHFIPAKLFGTRVEKFYLFFDVKFSLFKKKIGDTVYGIGWLPLGGYVKIAGMIDESMDKEQMAQEPQPWEFRSKPAWQRLIIMLGGVTVNFILAYFIYVGLAFAYGDKTTSLASLKDGYWIENQLLQDIGFKTGDKILKVNDMEVVNDYDVRSNIIGAENFTIDRDGETKVIALPEDFLGQFTSADSRQLFERRIPFMVGEIADSSFNKSSDLKVEDIITSIEGQELKYFDQLNSIMANYKNKTVQVGVLRGNDEFTATLKVDENGKFGIFPGMDRDRFAELGYFDITLQTYTFGESFAEGGRDFVETMQKYGAQLKAIFNPSTGAYKGVGGFKAIFDIFPPFWSWQAFWVLTAFLSVMLGVLNLLPIPALDGGHVMFLLYEMVSGRAPSEKFLERAQLVGFIILIVMVLSANINDWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI87</accession>
    <name>A0A5C6ZI87_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">N-acetylglucosamine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_10515</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="287" mass="32663" checksum="5304A4025F85E381" modified="2019-11-13" version="1">MVLIVDSGSTKCDWIAVDTSGKQLQEKIRTHGLNPAILTEKQLKKIIKESEELKQIKGEVTHLFFYGAGCGTDKPKATMLQVLQAFFEKAMIDVQEDTMAAVRATLSHDDEAAVVCIMGTGSNCSYYDGNVLHQRVKSLGYSLMDDASGNYFGKELIKDYYYNNMPEDIRVAFEHKYNMEADFIKHNLYKQPNPNAYLANFAEFMFLNKESKYMDGLIKSGFRVFVKNMIFQYKEELKTVPVHFAGSIAFFSKKQILQVADEMGFKVGNFARRPIEGLLKYHTKNLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZII3</accession>
    <name>A0A5C6ZII3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">YihY/virulence factor BrkB family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_10900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017039">
        <property type="entry name" value="Virul_fac_BrkB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30213">
        <property type="entry name" value="PTHR30213"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03631">
        <property type="entry name" value="Virul_fac_BrkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF035875">
        <property type="entry name" value="RNase_BN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="34"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="95"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="146"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="181"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="217"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="252"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="303" mass="33507" checksum="3F82D5DFF1F24389" modified="2019-11-13" version="1">MVSKALSLKNIPKLMGKTAKVWFNDEPFRLSAIIAYYAILSLPALIIIIMNVVGGIWGKEIVQGELLGEISEAIGTEAAESIRMMIVDQGDKSTSLFATIVGIGTLLYGATGVFFQLQESFDKIWKTKPKYTNGIIATIMSRLKSIGFILILGFLLLVSFVLTSLLSTFSNRLELFLPEKLLKYVFIFDILISLGFIYVLFGAMFKFLPSKPISWKAVRVGAAITAILFIIGKYLLAIYFSTMQPGSTYGAAGSIILVMLWVSYSSLILFYGAHFTKVYADEYGLSIDNNDDEALDEALEEIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIJ4</accession>
    <name>A0A5C6ZIJ4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GSCFA domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12305</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014982">
        <property type="entry name" value="GSCFA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08885">
        <property type="entry name" value="GSCFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GSCFA" evidence="1">
        <location>
            <begin position="22"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="320" mass="37009" checksum="78B15ABF2D14BE29" modified="2019-11-13" version="1">MNLQTKLLLQPSTANPIDYNSKVLLLGSCFSEHIGDKFGYFKFQHLQNPFGILFHPLAIERLISKASAEKRFTKNDVFQHNEQWHSFDAHSRLSHTSAEKLVEILNVQIEQTHQYITAATHIIITLGTAWAYKLKATQQTVANCHKLPQNDFDKHLLSVDAISEALERISETIYSHNKKVSLIFTISPVRHLKDGFVENTQSKAHLITAVQQVLRTKDKGRPVSFYFPSYELMMDELRDYRFYAADMIHPNSTAIDYIWERFNEQWISKDTQAVMEDVQSIQKGLAHRPFNPKSEAHQTFLQNLKGKQEALRTRFPHLGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIK8</accession>
    <name>A0A5C6ZIK8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Putative membrane protein insertion efficiency factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">yidD</name>
        <name evidence="2" type="ORF">ESY86_04590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Could be involved in insertion of integral membrane proteins into the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0161 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00386">
        <property type="entry name" value="UPF0161_YidD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002696">
        <property type="entry name" value="Membr_insert_effic_factor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33383">
        <property type="entry name" value="PTHR33383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01809">
        <property type="entry name" value="YidD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01234">
        <property type="entry name" value="Haemolytic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00278">
        <property type="entry name" value="TIGR00278"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="78" mass="8864" checksum="98386053FC8A8389" modified="2019-11-13" version="1">MKKLLTYPFLFLIKVYQSLISPFFPASCRFQPTCSQYAKEALLIHGIWKGGKLAVIRIFSCHPWGGSGYDPVPKKDDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIN8</accession>
    <name>A0A5C6ZIN8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase family 4 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_09830</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="210"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="389" mass="45066" checksum="0CABAA19B422242B" modified="2019-11-13" version="1">MHKILFLQSHPIQYHSPLYDKLEQNELVEFKIYYCSDYGLSQDGKRFHPEFGELPNWDVDLVNGHTYEILKNSALKKGIFNGFFGLMNFGIYAKLKSDRPDVLVINGWNYFTMIWAVFCCKFLKVKVYARGDNSIDGDKQLSNLKLIMKHFLYGKLLFPLFTKIGYVGKKNKEFFESYGVKYAKLINLPHAIDNERFIKYYERHRNNKIEIRRQLGISSAFNVLFIGRLHQEKRIFDLIEAVGKIPEKVQLTIIGDGKLQDKVRQACEAYPNHTFNLIGFQNQEELLEYYITGDLMVLPSQLETWGLVVNEAMNFDLPIILSDTVGCAEDLCQEKNGYIYKMGDVNSLSSHIDYLTKNSNIAKKMGVKSGEIVKDYSYESIIKNLIQSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIR4</accession>
    <name>A0A5C6ZIR4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_11510</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="116" mass="13507" checksum="E1969D9EE3726CEB" modified="2019-11-13" version="1">MNKKEPLTKLKHVKGLGKDEKAYLTNLINTKKKYGLVLEHKAEGVEEDLRHKLPILKEVKEHAMMNDIERKKNPNYILIEVDNYHILTSLSFTHYNSMDVIYLDLPYNAGAKEMPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIV4</accession>
    <name>A0A5C6ZIV4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Mechanosensitive ion channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_10580</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045275">
        <property type="entry name" value="MscS_archaea/bacteria_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011066">
        <property type="entry name" value="MscS_channel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011014">
        <property type="entry name" value="MscS_channel_TM-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008910">
        <property type="entry name" value="TM_helix"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30221">
        <property type="entry name" value="PTHR30221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05552">
        <property type="entry name" value="TM_helix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82689">
        <property type="entry name" value="SSF82689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82861">
        <property type="entry name" value="SSF82861"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="73"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD88932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="299" mass="34461" checksum="CA1ACD4ABE0EF2A2" modified="2019-11-13" version="1">MIRFLEIGIYMDKLKDKLLGWYEELILRLPNLILAIFTLFLFYFIAKGVASLVSKILRARMDNISVRHIIKKLIFLVILLIGFFISLNVLGLDKALATILAGAGVIALAFGLALQGTLNNTFSGVLLSFLPRIRIHDYIETENHKGFVEEISLRNFVLRQPDNHIVVMPNSLIVDKPFVNFSLTERSRITVKCGVAYSSNLREVRDMIMKLMTDNFPQEAGEKIEFYWLEFGDSSINFMTRFSCVYQRPGQMFDRQSEAIMLIKEEFDRNNINIPFPIRTLHMGTNVEIAKEREPKNEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIZ0</accession>
    <name>A0A5C6ZIZ0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_10855</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022922577" evidence="2">
        <location>
            <begin position="21"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="389"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="584" mass="67219" checksum="3E51F98150FCA2CE" modified="2019-11-13" version="1">MLKSIYLFTMALFWFSIAVSQDNAAKSKKALAEFKAITAAMNAEFPEDKANTFRRSSFTDKQLQSYLSQHFQRLDLLPKIEGQHALKLNAYNYSGNWFLQIGFPRESIKCYDKFFKYYEGSKTALTATELVSLANKITYSYASLAKNLAEIGDLASAQKIHKDNIAYAEKNKDVYYPSALNNYGLYFYWYKKDLDSAAIYFNTAYEITKQNFTEHTIIGSIRDNIADLNLDKGRLRDALSLYEINFEFYKRAINENTLEKDYPRLISAGSQVVSTSAKLGDLGKAEKAFDELRIIVEGAKNAALGSASSTLGFLEAKEQLLFHSNKLAEAYQTTKTIRRFSDSLNRVAEKAEEIWRQELNDVTLDRVALNFEIDKLQTENKIKKQRSRLWISGLLSSVFIIILLFLFLSRRQRLINAKNEKLLAEHKFENSVLKVKQLNSEIESKKRDLTDFAISLTQNQDWIKDISTQFEQIKASQTSQKEELLMQLEHDIANKINYDDETKIFFERLAKLSDTFYKKLNAAFPNLSKNEINLCSLIRLKIESRSIATLQNITLASLNTSRYRLRKKLDLSEATDLDIFIQNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ06</accession>
    <name>A0A5C6ZJ06_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DUF4968 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_10335</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032513">
        <property type="entry name" value="AGL_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033403">
        <property type="entry name" value="DUF5110"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030458">
        <property type="entry name" value="Glyco_hydro_31_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025887">
        <property type="entry name" value="Glyco_hydro_31_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16338">
        <property type="entry name" value="DUF4968"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17137">
        <property type="entry name" value="DUF5110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13802">
        <property type="entry name" value="Gal_mutarotas_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00129">
        <property type="entry name" value="GLYCOSYL_HYDROL_F31_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4968" evidence="4">
        <location>
            <begin position="25"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="Gal_mutarotas_2" evidence="3">
        <location>
            <begin position="144"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5110" evidence="5">
        <location>
            <begin position="692"/>
            <end position="759"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD89155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="803" mass="93589" checksum="B7FF5621364B7AAD" modified="2019-11-13" version="1">MITNTELEHKGNLTPSKIIGFRKDVDRLYFSTDNDVVLQVTVLRDSVLRFRYTTTGTFTKDFSYAITKYASTGYNHLEIEELKTFYKITTSKLECHISKLNLGVQIYDVLDKRLINQDEIGFHWEESYVHGGNFVKMSKVSNDGESYYGLGDKPSHINLKGKRFENWVTDSYAYGKDSDPIYKSIPFYTGLHHNKAYGIFFDNSFRSFFDFAQERRNVTSFWAMGGEMNYYFIYGPKMTEVVESYTDLTGKPHLLPPMWALGFHQCKWSYYPEKKVKSIANNFRKLKIPCDAIYLDIDYMDGFRCFTWNKDYFPDPKRMVKELLDDGFKTVAIIDPGIKIDKEYSVFREALENDYFCKRADGPYMKGKVWPGECYFPDFTNPKVRDWWAGLFQELIEDIGVKGVWNDMNEPAVMEVPNKTFPDDVRHEYDGNRCSHRKAHNVYGMQMARATYQGLKKFAYPKRPFVITRAAYSGTQRYTSTWTGDNVATWEHLWIANVQAQRLAMSGFSFAGSDIGGFAEQPQGELFTRWVQLGIFHPFFRVHSSGDHGDQEPWAFGKNVTDVVRKFIEIRYQLLPYLYTTFWNYVEDGTPILKSLVLYDQEDVHTHYRTDEFVFGNQILVCPILEPNAKGRRMYVPNGNWYSFWDDSIIEGGLELWVDADIEEMPIYIKEGAVIPKYPIQQYVGEKKIETVTLEVYYKEGKEVSQLYDDAHDGYDYTKGRYSLRTFKLTGKPNELIIQQHKEGKFDAEYGNFEIKLHGLPFEIEEIQVDNVVIPVKELIKNGNSEMTIDKEFSQLHLIGKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ41</accession>
    <name>A0A5C6ZJ41_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF2853 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_06150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021274">
        <property type="entry name" value="DUF2853"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023154">
        <property type="entry name" value="Jann4075-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11015">
        <property type="entry name" value="DUF2853"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158587">
        <property type="entry name" value="SSF158587"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="113" mass="12549" checksum="783059C6493D3F65" modified="2019-11-13" version="1">MSKRDDLIAKYAEDLKDKCGVNPDMDLLKKVTIGCGPSIYNADAAVVSGTTESELATVKNNFLIKKLGLKDGPELDKAISAVIEKYGQSNRNKYRVVVYYLLATHFKKESVYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ61</accession>
    <name>A0A5C6ZJ61_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3 4">Single-stranded DNA-binding protein</fullName>
            <shortName evidence="2">SSB</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_05540</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_026813265.1">
        <property type="nucleotide sequence ID" value="NZ_VORO01000004.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04496">
        <property type="entry name" value="SSB_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00984">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000424">
        <property type="entry name" value="Primosome_PriB/ssb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011344">
        <property type="entry name" value="ssDNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10302">
        <property type="entry name" value="PTHR10302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00436">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002070">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00621">
        <property type="entry name" value="ssb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50935">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR002070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="114" mass="12805" checksum="28A453E339F53F5F" modified="2019-11-13" version="1">MSTIKNHVQLIGNVGQEPTITNLESGKKVARFSLATNEYYKDKEGNKQTDTNWHTVVAWGKTAEIVEKYVVKGKEVGISGKLKTRSYTNDDNEQRYVTEVVADEILLLGSKDDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ74</accession>
    <name>A0A5C6ZJ74_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">3-oxoacyl-[acyl-carrier-protein] synthase 2</fullName>
            <ecNumber evidence="3 10">2.3.1.179</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">fabF</name>
        <name evidence="14" type="ORF">ESY86_08150</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Involved in the type II fatty acid elongation cycle. Catalyzes the elongation of a wide range of acyl-ACP by the addition of two carbons from malonyl-ACP to an acyl acceptor. Can efficiently catalyze the conversion of palmitoleoyl-ACP (cis-hexadec-9-enoyl-ACP) to cis-vaccenoyl-ACP (cis-octadec-11-enoyl-ACP), an essential step in the thermal regulation of fatty acid composition.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>(9Z)-hexadecenoyl-[ACP] + H(+) + malonyl-[ACP] = 3-oxo-(11Z)-octadecenoyl-[ACP] + CO2 + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:55040"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10800"/>
            <dbReference type="Rhea" id="RHEA-COMP:14074"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:83989"/>
            <dbReference type="ChEBI" id="CHEBI:138538"/>
            <dbReference type="EC" id="2.3.1.179"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a fatty acyl-[ACP] + H(+) + malonyl-[ACP] = a 3-oxoacyl-[ACP] + CO2 + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:22836"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:14125"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:138651"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10 12">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.179" evidence="3 10"/>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00834">
        <property type="entry name" value="KAS_I_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017568">
        <property type="entry name" value="3-oxoacyl-ACP_synth-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000794">
        <property type="entry name" value="Beta-ketoacyl_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018201">
        <property type="entry name" value="Ketoacyl_synth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712">
        <property type="entry name" value="PTHR11712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000447">
        <property type="entry name" value="KAS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03150">
        <property type="entry name" value="fabF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00606">
        <property type="entry name" value="B_KETOACYL_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10 14" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8 10" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 12 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_KS" evidence="13">
        <location>
            <begin position="6"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00014657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR000447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000447-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TXD89354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="416" mass="44310" checksum="3758B15344608238" modified="2019-11-13" version="1">MELRRVVVTGLGALTPIGNTKDEFWEALISGKSGAAPITYFDTEKFKTKFACELKNFNATDFLDRKEARKMDKFTQYAMVASDEAIADAKLNLDVVDKLRVGVIWGAGIGGLETFQEEVLNFAAGDGTPRFNPFFIPKMIADIAPGNISIKHGFMGPNYTTVSACASAANAMIDALNYIRLGHCDVVVTGGSEAAVTIAGMGGFNAMHALSTRNDSPETASRPFDATRDGFVLGEGAGAIILEDYEHAKARGAKIYAEVLGGGLSSDAYHMTAPHPEGIGVIAVMRNCLKNAGIEPEEVDHINTHGTSTPLGDVAELKAITEVFGKHAKNININSTKSMTGHLLGAAGAIESIASILAMEHGIVPPTINHKVVDENIDPQLNLTLNKAQKRDVKVAMSNTFGFGGHNACVLFKKLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJG7</accession>
    <name>A0A5C6ZJG7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06785</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023137610" evidence="1">
        <location>
            <begin position="24"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="358" mass="40268" checksum="B8F354F86B39E130" modified="2019-11-13" version="1">MKTFKPILLLALGLLLTTTSCRTEDDLSIDPPQETTLAANSALASQMQRIAMNDGSVDNIVYNANCFTIQLPITVTINSVVITINDIGNYDDIEDLLDEFDDDDDTVDIDFPISIILADYTEIEINSLDELEDYADDCNDENEDDDDIECIDFVYPITASVFNSNNEVIATVTFNSDSDLYGFIDDIEDDDFVGFNFPVSIVISDGSVLVINNFNELEDAIDIYEDDCDDDDDYDYNDDDCNNCTPDQLESVLTACSDWYIDELERNDQDLEDNYSGYLFNFFADNTITVSWDGNTADGTWSASGTGNNITVTFNIPGFEDINDTWNLYEIENDDDEVEVKFEIGDDDELDFKNDNCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJK2</accession>
    <name>A0A5C6ZJK2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetyl-CoA carboxylase biotin carboxyl carrier protein subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_03235</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001882">
        <property type="entry name" value="Biotin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00188">
        <property type="entry name" value="BIOTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0092">Biotin</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="2">
        <location>
            <begin position="83"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="161" mass="17779" checksum="9D803654D84CBB97" modified="2019-11-13" version="1">MSQSFKVNVNSTFDFDITAAESEQLDSVKTASQQSHILKDQKSYSTEILKSNFLKKTYQVKVNNNSYHVAIANDLDQLITAMGFELGSSKVINEIKAPMPGLILDIPIKVGQEVEENDTLLILEAMKMENVLSSPRAGVIKSISVKKGDAVDKNALLLEFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJU8</accession>
    <name>A0A5C6ZJU8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MBL fold metallo-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_04950</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022712">
        <property type="entry name" value="Beta_Casp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011108">
        <property type="entry name" value="RMMBL"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10996">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07521">
        <property type="entry name" value="RMMBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01027">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="17"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-Casp" evidence="2">
        <location>
            <begin position="251"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="457" mass="52030" checksum="C130D8DECCA9E7EE" modified="2019-11-13" version="1">MDHHVKINFLGAAGVVTGSKFLIETSEKTILIDCGMFQGLKELRELNWCDLPIDVNAIDLVLLTHGHLDHVGYLPRLLKQGFQGKIVGTAPTLAIAEIILRDSAKIHEEEAERANKEKYTKHHPALPFYTVKDAETTIQLFEVEMEDKWIHLSEHISYRFQYNGHIIGATFIELDINSKRLVFSGDIGRSNDYLLEDPKRPEWADFLFVESTYGNKLHSEEDVEQILTDIILETIHKKGNLIIPSFAVERLQTLMYILWKLYQKNKIPNIPIFVDSPMGSNVLDVFSRFPKWHKLPMAEYNAMCNHVNSVQSYKETWETIDDKRSKIVIAGSGMVTGGRVLTYLQQLIDEPSTTVLLVGYQAEGTRGRQLFDGAHEIKFSGKYYPVKATVKHIESLSAHADQNGLLNWMSAIKNIPEKVYLIHGEPAALDAFRVKIKDTYNWNVTIPKLSDVETLVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK63</accession>
    <name>A0A5C6ZK63_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="165" mass="18857" checksum="74E5D1754250C282" modified="2019-11-13" version="1">MTKNNLHSIKNSGFKVPDGYFDQVETAICNDISLREKIEASGFTTPKGYFEHFEDHLLGQLPKEENDKAIPLYNRTKVIFAIAIAACLVLMLSILFNTTQELTFDTLETAAIENYLEEEDYTDDDLATLFMENELSTFDFIEVKISEDTANEFIDSIDIEDYILN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK66</accession>
    <name>A0A5C6ZK66_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 10">Phosphoglycerate kinase</fullName>
            <ecNumber evidence="2 7 10">2.7.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pgk</name>
        <name evidence="12" type="ORF">ESY86_08035</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7 10">
            <text>(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:14801"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57604"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7 11">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 10">Belongs to the phosphoglycerate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.3" evidence="2 7 10"/>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004618">
        <property type="term" value="F:phosphoglycerate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00318">
        <property type="entry name" value="Phosphoglycerate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1260">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00145">
        <property type="entry name" value="Phosphoglyc_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001576">
        <property type="entry name" value="Phosphoglycerate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015824">
        <property type="entry name" value="Phosphoglycerate_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036043">
        <property type="entry name" value="Phosphoglycerate_kinase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11406">
        <property type="entry name" value="PTHR11406"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00162">
        <property type="entry name" value="PGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000724">
        <property type="entry name" value="Pgk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00477">
        <property type="entry name" value="PHGLYCKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53748">
        <property type="entry name" value="SSF53748"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="5 7 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 10" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="7 8">
        <location>
            <begin position="19"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7 8">
        <location>
            <begin position="58"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="292"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="323"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <begin position="352"/>
            <end position="355"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000724-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000724-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TXD89721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="395" mass="42513" checksum="7303ED1E5484FCD5" modified="2019-11-13" version="1">MKTINDFNFKNKKALIRVDFNVPLNDAFEVTDANRIESAKPTIMKILEDGGSCILMSHLGRPKGVQDKFSLKHIVKKVEDVLGVEVKFATDSVGEAAQKAVANLQPGEIVMLENLRFHEEETSGDAEFAEKLSKLGDIYVNDAFGTAHRAHASTTVIAQFFPDKKCFGKLLAQEIESIDKVMKTGEKPVLAILGGAKVSSKITIIENILDKVDHLIIGGGMTYTFIKAQGGKVGDSICEDDKMELALEILNEAKAKNVKIHLPVDVVAADDFANDANTQIVEVDKIPDGWQGLDAGPKTNQMFHDVVLKCKTILWNGPLGVFEMENFAKGTISLGEAIAEATKNGAFSLVGGGDSVSAVKQFGFENKVSYVSTGGGAMLESLEGKTLPGIAAILD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKA8</accession>
    <name>A0A5C6ZKA8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF5606 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_04560</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041218">
        <property type="entry name" value="DUF5606"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18347">
        <property type="entry name" value="DUF5606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5606" evidence="1">
        <location>
            <begin position="3"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="143" mass="16459" checksum="A7DD794ED5F49049" modified="2019-11-13" version="1">MSLDKVLSISGKPGLFKILTQTRNGFVVESLLDKKKVNVTMQNNISVLSEIAIYTLTEEVPLRQVLNNIMEKEDGKPTSISPKDSKIKLEEYFFEILPDYDEDRVYASDIKKIMQWYNLLQQHDMLDVLEAPSEEKEASSEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKB6</accession>
    <name>A0A5C6ZKB6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Exosortase F system-associated protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026414">
        <property type="entry name" value="ExosoTase_F-assoc_pro"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04127">
        <property type="entry name" value="flavo_near_exo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="145" mass="17638" checksum="5F232F1EA352925B" modified="2019-11-13" version="1">MRNPIRFIVLLVLFGLLVLVRVFENELFYDPYLLFFKNDYLYMDFPNREILKLTLFTSLRYVLNSALSLGIIYLFFKDVSILKFSTLIFSIAYVLLILVFLYFVIHPRQEDYYLFFNVRRFLIQPLPLLLLLPAFYYHKLRHDKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKK2</accession>
    <name>A0A5C6ZKK2_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">dITP/XTP pyrophosphatase</fullName>
            <ecNumber evidence="6">3.6.1.66</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Non-canonical purine NTP pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Non-standard purine NTP pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Nucleoside-triphosphate diphosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Nucleoside-triphosphate pyrophosphatase</fullName>
            <shortName evidence="6">NTPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_10330</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>H2O + ITP = diphosphate + H(+) + IMP</text>
            <dbReference type="Rhea" id="RHEA:29399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>H2O + XTP = diphosphate + H(+) + XMP</text>
            <dbReference type="Rhea" id="RHEA:28610"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:61314"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>dITP + H2O = dIMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28342"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61194"/>
            <dbReference type="ChEBI" id="CHEBI:61382"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the HAM1 NTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.66" evidence="6"/>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035870">
        <property type="term" value="F:dITP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036220">
        <property type="term" value="F:ITP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017111">
        <property type="term" value="F:nucleoside-triphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036222">
        <property type="term" value="F:XTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009146">
        <property type="term" value="P:purine nucleoside triphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00515">
        <property type="entry name" value="HAM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01405">
        <property type="entry name" value="Non_canon_purine_NTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020922">
        <property type="entry name" value="dITP/XTP_pyrophosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002637">
        <property type="entry name" value="Ham1p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11067">
        <property type="entry name" value="PTHR11067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01725">
        <property type="entry name" value="Ham1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
        <property type="entry name" value="SSF52972"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00042">
        <property type="entry name" value="TIGR00042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="7"/>
            <end position="12"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="148"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="176"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="68"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD89154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="191" mass="21101" checksum="2D51F36D6BAC88F3" modified="2019-11-13" version="1">MKIVFATNNPNKLKEVQSLIPKKIQLLSLEAIGCTEDVPETQSTIEGNAKQKADYIKTHYGYDCFADDTGLEVEALHGEPGIYSARYAGKQRDANDNMDKLLNNLEDKPNRNAQFKTVIALHLSGKTKTFTGICKGAITTAKRGKDGFGYDPIFKAEGFDQTFAEISLAEKNEVGHRGKAVRQLVAYLTKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKR5</accession>
    <name>A0A5C6ZKR5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">PorT family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_07025</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="412" mass="48255" checksum="AF4CCDC96B5678B5" modified="2019-11-13" version="1">MSFKTKLKPNLLVYFLTFTCIINAQTQYEKGYFIDNNQNKVECLIENVDWKNNPEDITYKFSETSEQKVADLSSISKFEIYDIAIYTREEVDLDINSTKANKLDYSEKLDLKKQTVFLKFLVGGKANLYVYQDANLKRFYYQIDDGEIAILIQKEYITSSNKVAENENYKGQLYYDLKCNSLDMSTIRSTDYVQSDLMALFEAYNSCKNQSLYTFKEKTRKNPFHLKIRPGINFAYVKYDAPGDNFVILTDFEFNQEMSFRLGIELEYILPFNNDKWAILFEPTYQYYNTEKTFDISPDSPVARIKTATVEYSSIEFPIGFRHYSHLNDNSRLFFNVSFLFDRPFKSNINYFDEDYEINSVSNLAFGAGYSYKNTYSIEARLFSTREILNTDVTNAGYKNVSVIFGYTILQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKT1</accession>
    <name>A0A5C6ZKT1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MgtC/SapB family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_02490</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MgtC/SapB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025105">
        <property type="entry name" value="DUF4010"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003416">
        <property type="entry name" value="MgtC/SapB/SrpB/YhiD_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13194">
        <property type="entry name" value="DUF4010"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02308">
        <property type="entry name" value="MgtC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="33"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="96"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="141"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="174"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="199"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="233"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="263"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="305"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="332"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="366"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="397"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4010" evidence="8">
        <location>
            <begin position="180"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD90847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="422" mass="45833" checksum="1789A9538562BD77" modified="2019-11-13" version="1">MNYQDLTTLGIALGLGLLVGLQRERTDNHMAGVRTFMLISILGVMAGFLAKVYDNPYILPVLGLAIAGMLIMANYIKLKKFDEADVGQTTEVAVLLMFVIGAYLVLGNRIVGVLVGASMAILLYIKEHLHGFIEKLKPKDLSAIMTLVGISLIILPILPDKTFGPFDVLNPRNIWLMVTLIVGISVFGYFIYKFFGRKVGVISNGILGGLISSTATTVSYARKTSEASSISKLAVFVITTASAVSFVRILFEVGVVIPDKFGVIALPIAAVIFVMALICVVLFYFINTEDTKDEEMPEPENPAQFKSALIFGLLYGFILLAVAFTKETFGNNALYIVSIVSGLTDVDAITLSLSQLIKEGSLEASFGWKLILLAGLSNMLFKGIMAIVLGAKSIAKWIAVSFGITIATGLLILWLWPESWYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKV4</accession>
    <name>A0A5C6ZKV4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptide methionine sulfoxide reductase MsrA</fullName>
            <shortName evidence="4">Protein-methionine-S-oxide reductase</shortName>
            <ecNumber evidence="4">1.8.4.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Peptide-methionine (S)-S-oxide reductase</fullName>
            <shortName evidence="4">Peptide Met(O) reductase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">msrA</name>
        <name evidence="6" type="ORF">ESY86_03585</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>[thioredoxin]-disulfide + H2O + L-methionine = [thioredoxin]-dithiol + L-methionine (S)-S-oxide</text>
            <dbReference type="Rhea" id="RHEA:19993"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58772"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 4">
            <text>[thioredoxin]-disulfide + H2O + L-methionyl-[protein] = [thioredoxin]-dithiol + L-methionyl-(S)-S-oxide-[protein]</text>
            <dbReference type="Rhea" id="RHEA:14217"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12315"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:44120"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the MsrA Met sulfoxide reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.11" evidence="4"/>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033744">
        <property type="term" value="F:L-methionine:thioredoxin-disulfide S-oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008113">
        <property type="term" value="F:peptide-methionine (S)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01401">
        <property type="entry name" value="MsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002569">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036509">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01625">
        <property type="entry name" value="PMSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55068">
        <property type="entry name" value="SSF55068"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00401">
        <property type="entry name" value="msrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PMSR" evidence="5">
        <location>
            <begin position="9"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD90459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="183" mass="19989" checksum="3D7A9D104F1B1671" modified="2019-11-13" version="1">MAKTQLEQLIVGGGCFWCIEAVFNELKGVTKVVSGYAGGSVPGTPTYREVGSGLTGHAEVVQVTFDANSISYRDLLHIFMSSHDPTTSNGREADFGSQYRSVIYYGNAIQKEIASVIVNEFSAYVERPITTEISPAEKFHAAEAYHQNYYANNSSASYCKAIIAPKLATLRSRYADKLKSIPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLE7</accession>
    <name>A0A5C6ZLE7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_08790</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="116" mass="12520" checksum="33E28463C34AF6DA" modified="2019-11-13" version="1">MKNLKNLTRATLFSVCLSIPFMGLMGCSSSDDSDDINTNCGNWSDLFLSQANLYSQASQAYADDPSPANCQNFKSAGLNYIDALEGAIDCVPTANVQGFNAELDQYRAEVNALDCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLF9</accession>
    <name>A0A5C6ZLF9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2911 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_04660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021314">
        <property type="entry name" value="DUF2911"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11138">
        <property type="entry name" value="DUF2911"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023010506" evidence="1">
        <location>
            <begin position="25"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="181" mass="20101" checksum="9C0503569BAF7E1F" modified="2019-11-13" version="1">MNIKSIISRLSFAMALLFAVSMSAQDFKGLDKSPMDGAAFPSDYKDANKLIRITYGRPQLNDRKIEDLAPSGKVWRTGANEAAELTLYTPMTLGGTQIEPGTYTFYVIPGEKEWTAIINKDLNVWGSYFYKEDQDVARISVPVTEGKESLEAFSIAFEKAEGGVDMHLGWGTMRVAVPFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLH1</accession>
    <name>A0A5C6ZLH1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022994678" evidence="1">
        <location>
            <begin position="20"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="302" mass="35555" checksum="93CB9052B53B2447" modified="2019-11-13" version="1">MKTPLYTLLALLFSISAISQTSKKQEDREAIKNMCGCYEVTFNFAETFNYSNDSLYKPSKTKVDKALEWAQLVTDEDDKISIQHLLQVGNPAEPQVVKHWRQDWLFENRDLYTYNADNEWTFEKLPAPEVIGQWTQKVYQVDDSPRYEGSASWVHVDGKSYWENTTPAPLARREYTTRSDYNLLMRGNRQEITDYGWLHDQDNTKIIRETGKEDIVLAKEKGYNTYVKVDDSICAAASQWWKDNDQKWALVRTKWDEVYGRNKDLVLEEKVDNKPLYKFLFEEEGYEKEAQIDEVIESFVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLK7</accession>
    <name>A0A5C6ZLK7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Na(+)-translocating NADH-quinone reductase subunit F</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_06055</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="125" mass="14306" checksum="F2EEFBBA22DFA6DD" modified="2019-11-13" version="1">MGKALTKQELHNLAMNHVGKDLEQRGFEFIAVNSKLKRHPQFVCIDKTSQYFFVIVKAVLLPANPNNYDLIWMETFKKHAFEKDAKVLYAGVGIGNPSGEHLPVYLNEEYLIEYNGIQVIEPNLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLM0</accession>
    <name>A0A5C6ZLM0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_02095</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="147" mass="15854" checksum="13114EBC6A749EAA" modified="2019-11-13" version="1">MTIQKIIKIIALVIGLIAIFFLVRIMMIGDEAIEADVANQSVLSNFATLAYIVLAIATFSAVVFSLINLVSNPDKLKKSLLSFAVFAVILVVAYFISSGEARQLSDGTTLTAGQSQLIEAGIKAFYILILLAAFLMLAFGVKKMFSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLM1</accession>
    <name>A0A5C6ZLM1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Iron-containing alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_03065</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the iron-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990362">
        <property type="term" value="F:butanol dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08187">
        <property type="entry name" value="BDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018211">
        <property type="entry name" value="ADH_Fe_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044731">
        <property type="entry name" value="BDH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43633">
        <property type="entry name" value="PTHR43633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00465">
        <property type="entry name" value="Fe-ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00913">
        <property type="entry name" value="ADH_IRON_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00060">
        <property type="entry name" value="ADH_IRON_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-ADH" evidence="3">
        <location>
            <begin position="9"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD90949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="386" mass="42439" checksum="CBBAB479FF1F4FD3" modified="2019-11-13" version="1">MKNFEFKNPTKILFGKGQIENIKNEIPNDAKVLMLYGGGSIKKNGIYEQVSTALSNHEVVEFGGIPANPEYSVLMEALKVIKEQKTTFMLAVGGGSVIDGTKFLSSAALYDGKEPWDILSKNIPTLKGMPFGTVLTLPATGSEMNSGAVITRADTKEKLAMGGAGLFPVFSVLDPEVIQSIPHRQLVNGITDAFTHVLEQYLTYPAGAKLQDRISESILQTLIEVAPKVLEDPTDYSAASNFMWSCTMALNGLIQKGVPTDWAVHAMGHELTALFGIDHARTLAVIAPSHYEYNFETKKEKLAQYAERVWNITEGSTESKAKAAIKRTEAFFNEMGIATKLSQYTNDYEGTAEEISKRFKARGWEGLGEHQNLKPEDAEQIVKMAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLM3</accession>
    <name>A0A5C6ZLM3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_07245</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023107401" evidence="2">
        <location>
            <begin position="22"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="206" mass="23353" checksum="835EDF10809E60F8" modified="2019-11-13" version="1">MKTIKIPLLALFLLNALFIFAQQSKQNINMKIDSIGNAKVTISMTMNASQWQQWNGSYGNNPSALKREIERGMPAFFVDDFKLDKDDMNRSFALSLNAYGACRIDKRGKWIMNTDQKDAQLTALTKHKYMLVSSPPEYGGSLQQIYTIELPEAAHQIKTDKDAFGKSTFEFKMDQPSGPFNYMRWSGVFLIVIGGAWFGKNAVTRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLN6</accession>
    <name>A0A5C6ZLN6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phytoene desaturase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">crtI</name>
        <name evidence="5" type="ORF">ESY86_06515</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1 3">Carotenoid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the carotenoid/retinoid oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00906">
        <property type="reaction ID" value="UER00895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016117">
        <property type="term" value="P:carotenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014105">
        <property type="entry name" value="Carotenoid/retinoid_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02734">
        <property type="entry name" value="crtI_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0125">Carotenoid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amino_oxidase" evidence="4">
        <location>
            <begin position="15"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD89850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="487" mass="54923" checksum="D9C63DE7C8263FF1" modified="2019-11-13" version="1">MKTSIGIIGSGFSALSAACYLAKAGNHVSMYEKNDTLGGRCRQFKKEGFTFDIGPSWYWMPDIFEKFFNDFGKKVSDYYELDKLDPAYKIFFDDDTITIGDTLEKISAEFERIESGSSVALNKFIAKAASNYDIAINKVVLKPGISPFELVTKDTITRVDQFFKTISSEVRKNFKNPKLISTLEFPVLFLGAKPGNTPAFYSFMNYADFGLGTWHPKGGMYEIVKAMTALAKSLGVEIHTESPVSQINVSDKKATSVVVNGKTLQFDVVLSGADYHHSETLLEEQHRQYSEAYWSKKTFAPSSLLFYVGYDKKLKNIEHHNLFFDTSFETHAEAIYDDPKWPEAPLFYANFPSKTDASMAPEGCETGFFLIPIAPDLEDTPELRETYFKKIMERFERLTGQSIEKNIIFKESFCVKDFISEYNSYKGNAYGMANTLSQTAFLRPKLKSKKIKNLYFTGQLTVPGPGVPPALISGKLVSELIKKHHNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLT4</accession>
    <name>A0A5C6ZLT4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2459 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_02480</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011727">
        <property type="entry name" value="CHP02117"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09601">
        <property type="entry name" value="DUF2459"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="215" mass="25037" checksum="DFBEA26220FC53F3" modified="2019-11-13" version="1">MKIAKKIFKYILYFLLIPVTYIIISLILSVITIDRKANDENFNKSIYLSTNGVHLDIVIPKEDIDSLVLSGMKHSETENYLSFGWGDENFYLNTPTWGDLTFSNAFKAMFLKSSTLMHVTRYKQKRTDWIEIKVNEFELQKLNTYLFSTFQSDENGMKILLKNKGYSPTDDFYKSKGSFSCFNTCNSWVNRGFKESGLKSSLWTPFDFGLLNKYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLU8</accession>
    <name>A0A5C6ZLU8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Acetyl-CoA C-acyltransferase</fullName>
            <ecNumber evidence="7">2.3.1.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_01430</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.16" evidence="7"/>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003988">
        <property type="term" value="F:acetyl-CoA C-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020610">
        <property type="entry name" value="Thiolase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00098">
        <property type="entry name" value="THIOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00099">
        <property type="entry name" value="THIOLASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase_N" evidence="5">
        <location>
            <begin position="5"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase_C" evidence="6">
        <location>
            <begin position="269"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="3">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="348"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD91274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="392" mass="41374" checksum="EE1D6433F55F84A8" modified="2019-11-13" version="1">MSREVVIVSAARTPIGSFLGSLSTVPAPRLGAIAIKGALDKIKLDPTLVNEVIMGNVVQAGEGQAPARQAAIYAGLPETVPCTTINKVCASGMKALMQAAQSIALGDTDIVVAGGMENMSLIPHYYYARTSNKFGPATMEDGMQKDGLVDAYDNNAMGVCADACATEYKFSREDQDNYAIQSYKRSAEAWANGKFDDEVVPVEVPQRRGDAIIVSKDEEFTNVKLEKIPSLRPAFTKDGTVTAANASTINDGAGAMVLMSREKADELGLKPLATIRSYADAAQEPKWFTTSPSKALPKALDKANLKLEDVDFFEFNEAFSVVGLANMKILGLDDSNVNVNGGAVSLGHPLGCSGVRIMITLLSVLQQNNAKIGAAAICNGGGGASAMVIERN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLX1</accession>
    <name>A0A5C6ZLX1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">RNA polymerase sigma factor RpoD/SigA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_02700</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009042">
        <property type="entry name" value="RNA_pol_sigma70_r1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007624">
        <property type="entry name" value="RNA_pol_sigma70_r3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00140">
        <property type="entry name" value="Sigma70_r1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04539">
        <property type="entry name" value="Sigma70_r3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000770">
        <property type="entry name" value="RNA_pol_sigma-SigE/K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r1_2" evidence="5">
        <location>
            <begin position="17"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r2" evidence="7">
        <location>
            <begin position="56"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r3" evidence="6">
        <location>
            <begin position="135"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4" evidence="8">
        <location>
            <begin position="222"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD90885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="287" mass="32626" checksum="4FAA6E47104D524E" modified="2019-11-13" version="1">MRQLKITKQVTNRESKSLDKYLQDISKLPMITAEEEVELAQRIREGDQQALDKLTTANLRFVVSVAKQYQNQGLTLPDLINEGNAGLVKAAKRFDETRGFKFISYAVWWIRQAILQALAEQSRIVRLPLNKIGSINKINKAFSYLEQAHERPPSAQEIAKELDMTLSEVKQSLKNSGRHLSMDAPLKEGETSSLYDVVKSGESPNPDAELMLESLNVEINRALDTLSQKESDVIRLNFGLSNEPPMTLDEIGLTFDLTRERVRQIREKGIKRLRQESKSKILKTYLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM02</accession>
    <name>A0A5C6ZM02_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Sulfate adenylyltransferase subunit 2</fullName>
            <ecNumber evidence="2">2.7.7.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">ATP-sulfurylase small subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Sulfate adenylate transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_07950</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PAPS reductase family. CysD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.4" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004781">
        <property type="term" value="F:sulfate adenylyltransferase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019419">
        <property type="term" value="P:sulfate reduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01713">
        <property type="entry name" value="PAPS_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002500">
        <property type="entry name" value="PAPS_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011784">
        <property type="entry name" value="SO4_adenylTrfase_ssu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01507">
        <property type="entry name" value="PAPS_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002936">
        <property type="entry name" value="CysDAde_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02039">
        <property type="entry name" value="CysD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PAPS_reduct" evidence="7">
        <location>
            <begin position="29"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="270"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00030256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD89704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="301" mass="34834" checksum="793A71D10ED11BDB" modified="2019-11-13" version="1">MSKYFLNYLDELESEAIFVLREVWAQFENPVILFSGGKDSILITHLAKKAFYPAKIPFPLMHVDTGHNFPETIKFRDDIISELGIQLIVGSVQEAINGGRVSEEKGKNATRNALQITTLLDAIESNKVDCAIGGGRRDEEKARAKERFFSHRDDFGQWDPKNQRPELWNIFNGKHFEGEHFRAFPISNWTEMDVWNYIKRENIAIPSLYFAHEREVVWRQDSWIPNSEFLVLESHEEVVTKKIRFRTLGDITITGGIESDADTLEKIADEVSGMRQTERGNRTDDKRSESAMEDRKRQGYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM91</accession>
    <name>A0A5C6ZM91_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyltransferase family 4 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_03840</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="412" mass="47359" checksum="DAF86BCC3B90FF53" modified="2019-11-13" version="1">MNKKLLIIGFVWPEPKSSAAGSRMLQLIYFFKAQDYQITFATACAKSNNAFDLEQIGVDKIGIKLNDASFDEFILKLKPDVVLFDRFMSEEQFGWRVADQLPEALRILDTEDLHFLRKAREAAFKSNAKNENDFLISDTTKREIASMYRCDLSLIISEAEVQLLRQRFEISSDLLFYLPFLVETPSEASKIELPKYQDRAHFMTIGNFIHPPNYNALLYLKETIWPKIRQQLPKAELHNYGAYAPQKVSELHNEKEGFLIKGWAEDVNEVMQDSRMLLAPIRFGAGLKGKIFDALQNGTPLITTTFGAEGIMTPEIANGFICDSPDAFSEAAVKLYENETLWLDKQAKGFEILSTKFSKSHFETEFAARLSRLVQNYKRERQQNFIGQLLQHHSLQSTKYMGKWIEAKHKKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMK1</accession>
    <name>A0A5C6ZMK1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">SDR family oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_01560</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="251" mass="26741" checksum="7EB3BAD16176F428" modified="2019-11-13" version="1">MNLKDKVVVITGAGSGIGKAAAKLFGKHKAIVVVSDINLEHAEKVANDIRNDGGKASAMETDVTQFEEVEELIKTVIKNHGSLDVMVNNAGIGGKQQAKTAEHSLDDWHNVIAVNQTGVFYCMKLALGQMRKQGYGNIVNVASLAGLKASGNNLSYSASKFAVVGMTKSAALEYGRKNIRINAVCPGFTHSALLEQLLSVSPDMGDKLKRFIPMGRFGEAEEIAEAICWLASENSKFITGQTITLDGGTSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-02-10" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMR4</accession>
    <name>A0A5C6ZMR4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">YqaE/Pmp3 family membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_06935</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0057 (PMP3) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000612">
        <property type="entry name" value="PMP3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01679">
        <property type="entry name" value="Pmp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01309">
        <property type="entry name" value="UPF0057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD89927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="51" mass="5619" checksum="02F921ECB90A2685" modified="2019-11-13" version="1">MPVYSVVLCILFPPLAVYLNKGSGRALVFSIVLTLLLWFPGMIHALITTDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMR7</accession>
    <name>A0A5C6ZMR7_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF5683 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_00625</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043738">
        <property type="entry name" value="DUF5683"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18935">
        <property type="entry name" value="DUF5683"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022977094" description="DUF5683 domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5683" evidence="2">
        <location>
            <begin position="55"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD91129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="200" mass="22648" checksum="F202A731246D59FD" modified="2019-11-13" version="1">MPNKSIYSFALLCFWSLLSFSQEDKPPEDVSTKNEVQTNLIRIQDSVKTEPLNVLAPAKAAFYSAVLPGLGQAYNKKYWKIPLVYAAIGIPAYFYVSNDKEYKRVRDAYKDRLAGVDQSGTEFANVSNDGLIRAQRGYRRNKELALLLSIVGYALNIIDANVDAHLMQFNVDENLSLRPHIQYNQRENASDVGLTLNFKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMU4</accession>
    <name>A0A5C6ZMU4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">M23 family metallopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_00795</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023087021" evidence="1">
        <location>
            <begin position="19"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M23" evidence="2">
        <location>
            <begin position="47"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M23" evidence="2">
        <location>
            <begin position="133"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD91159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="561" mass="64025" checksum="5D8E87A3E8F231E5" modified="2019-11-13" version="1">MKYLIFPILCLQFVLAHAQYPQDYFRSPLDIDLVLAGTFGELRSNHFHSGMDIKTQQRTGLNVYAVAEGYVSRIDVSNYGYGKALYITHPNGYVSVYAHLEKYAPEIEKYVKACQYAKESYEVEEFPAASELPVSAGDLVALSGNTGSSGGPHLHFEIRDNAERPINPMLFGFEVPDKKLPYISSVYAYPKDRNSHVNESKKRVELRLIPKSDGDYTVAPIEAFGEIGFGIESNDELDGANNKNGLGSIETFFNGNKNFQIDFKRFSFAETKHLNRYIDYELYKDKSARVQKLFIQPGNTLSMFKDVENDGYVKIEDSTDSVYKIRILDFKGNDTWLSIPIVAKPAKEILEAYELNPNTYINASTANELEQENVSVNFRPNTFYEDFNIDFSVRSDTLRLHKDVVPLMNYYSIQYDISNYADDDKQQLFIAQLYGYYQRPSYISTKRIGDKLSASTKTLGTFALARDTVNPSIRPVNFKDKQWLSKSSSLVLKISDDLSGISNYRATINGKWILMEYEYKRNTLTYDFSDNINTDTENNFKLIVTDNVGNSATFEATFYRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN29</accession>
    <name>A0A5C6ZN29_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phenylacetate-CoA oxygenase subunit PaaJ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">paaJ</name>
        <name evidence="2" type="ORF">ESY86_01930</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002744">
        <property type="entry name" value="MIP18-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011883">
        <property type="entry name" value="PA_CoA_Oase4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01883">
        <property type="entry name" value="FeS_assembly_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="SSF117916"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02159">
        <property type="entry name" value="PA_CoA_Oxy4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FeS_assembly_P" evidence="1">
        <location>
            <begin position="13"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="166" mass="18246" checksum="C38DD2B78A802AA2" modified="2019-11-13" version="1">MTTTEQNIDKKLIEILEAVSDPEIPVLSIMDMGVVRSAVIKNNKVKVEITPTYSGCPAMDVIGDDIKTALEDAGYEAEVELILHPAWTTDWITPRGRKALEDYGIAAPLGAEADIDVLLNGKRIVKCTNCGSQNTRLVSQFGSTACKAQFQCDDCQEPFDYFKCLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN55</accession>
    <name>A0A5C6ZN55_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Efflux RND transporter periplasmic adaptor subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_02725</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021782">
        <property type="entry name" value="DUF3347"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045800">
        <property type="entry name" value="HMBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11827">
        <property type="entry name" value="DUF3347"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19335">
        <property type="entry name" value="HMBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMBD" evidence="4">
        <location>
            <begin position="46"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="3">
        <location>
            <begin position="112"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3347" evidence="2">
        <location>
            <begin position="439"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF19335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="572" mass="62730" checksum="C8911F1C01AAAB80" modified="2019-11-13" version="1">MKKYIIYIALLIAGLVLGYVFFGTSSEGSANTKNVSDTSETQIQMWTCSMHPQIMQPEPGDCPICGMDLIPAESSAEGLAMNEIKMTENAMALANIQTTVVGNAAASDADGMISLSGKIAANEENNSVQASYFDGRIERLNVNYEGQQINRGQLLATIYSPNLVAAQQELLTTASLKESQPALYKAVRNKLKNWKLSDQQIDAIESSGNVRDNFPIYATVSGTVSEVMAREGDYVKQGQPILKVSNLNSVWAEFDAYENQISNLKDGQKIKVVANAYPNKEFDASVSFIDPLLNNATRTVTVRATLKNTEDLFKPGMFVTGKLKGAMKTTAETLTVPASAVMWTGERSLVYIKTNPNLPVFEMRGVTIGNRNGEFYTITQGLQNGDEIVTNGTFTVDAAAQLQGKKSMMNQGKTVKETMPMADMKIELSASFQKNFTKVFSPYLQMKDAFVDSDAAQVSIFAKATSKSLKSIEIDALGKMEQSHIIKSIEMLDAIAINDKLENQRAHFVILNENIIPIAVNLKDVNPILYVQKCPMANNNKGAVWLSTEEDIRNPYYGEQMMTCGSVIDSVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNG5</accession>
    <name>A0A5C6ZNG5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="15">T9SS type A sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">ESY86_04025</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011096">
        <property type="entry name" value="FTP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025711">
        <property type="entry name" value="PepSY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023612">
        <property type="entry name" value="Peptidase_M4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001570">
        <property type="entry name" value="Peptidase_M4_C_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013856">
        <property type="entry name" value="Peptidase_M4_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07504">
        <property type="entry name" value="FTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03413">
        <property type="entry name" value="PepSY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01447">
        <property type="entry name" value="Peptidase_M4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02868">
        <property type="entry name" value="Peptidase_M4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00730">
        <property type="entry name" value="THERMOLYSIN"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0732">Signal</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022735716" evidence="9">
        <location>
            <begin position="21"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="domain" description="FTP" evidence="13">
        <location>
            <begin position="92"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="PepSY" evidence="12">
        <location>
            <begin position="175"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M4" evidence="10">
        <location>
            <begin position="269"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M4_C" evidence="11">
        <location>
            <begin position="338"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="domain" description="Por_Secre_tail" evidence="14">
        <location>
            <begin position="778"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="328"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR623612-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF03413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF07504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF18962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TXD90543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="852" mass="93536" checksum="49C8D3ADA40FE8DD" modified="2019-11-13" version="1">MKKIALLFCCFLVINFASFGQNGNKTIQKLKSETKAQVTINPSNGIVEFIKFPAQQPFALKGNTLQQKAFTFLDAFADLYAIENSELQFTSQEIKTDNYGFKQLILKQVHEGVPVYDGQLRFHFDKNLKLTAINGTVIPNIKTEATAVLSSSAAGQIAVQLVEKQQINYSKQALEIFDTKRYIFPKGLAQGYVGNTYLVYEVEIRNNADVREFLYIDANTGKLVEQFTGIAHALNRQVYEENYSNLVWQEGDALPGDLDIFQQTEVLASGHMYHLFNNAFNYDSYDGAGRTMRTINNNPNIDCPNASWNGVTANYCTGTASDDVVAHEWGHAYTQFTSNLIYAYQAGAINESYSDIWGETVDLLNNYSDDLEDLSVRTFCNSSDRWRIGEDASAFGAPIRDMWNPNCNNDPGKVSDLQYRCGEGDSGGVHSNSGVPNHAYVLLVDGGSYNGQIIEALGFTKAAHVFWRAQSSYLTATSDFVNLADALEASATDLIGINLKGLSVTDVDAGLSGQSISANDLLQVVKAMLAVEMRLDPEACEYQPLLADSEALCNAATTGRVFFEDWETGTEGWNFEELPENAETWNTRFWTVEGNLPDGKPGQAVFAEAGLIGDCVNDFENGIMRLESPVINLPNIESGNFDLSFDHYLATEANWDGGNLKYKLNGGLWAIVPSEAFTVNPYNGVLNTAAAGNDNPMEGQAAFNGTDGGSLLGSWGTSVIDLSVLNASANDTVQFRWEMGTDGCNGRIGWFVDNIAVYNCSAETLSVSSSTLQNEIQVYPNPSNGLFKLKKMNNISLLKASVYDINGRLIQQVNLSEMTTEASIDMTNASTGMYFMKVQSASAEATFKLIKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNU8</accession>
    <name>A0A5C6ZNU8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PA2169 family four-helix-bundle protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_01260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011971">
        <property type="entry name" value="CHP02284"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019052">
        <property type="entry name" value="DUF2383"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016920">
        <property type="entry name" value="UCP029477"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09537">
        <property type="entry name" value="DUF2383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029477">
        <property type="entry name" value="UCP029477"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02284">
        <property type="entry name" value="TIGR02284"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2383" evidence="1">
        <location>
            <begin position="9"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="152" mass="17114" checksum="66B7D606E8F3E9F5" modified="2019-11-13" version="1">MSTYTEEVGKKLNELLEKTYDAEKGFKNAAEQIEHPALKSYFNQKAQERYNFGHELKTEIKSFGQEVDKGGSLTGSAHRAWMNVKALFSGDNEESMLEEAITGEKASVEEYNEVLQETSLPSSTRSILNSQKQTIETGLSNIKNLEDLRDSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNV3</accession>
    <name>A0A5C6ZNV3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Aquaporin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_01320</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015267">
        <property type="term" value="F:channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022357">
        <property type="entry name" value="MIP_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="SSF81338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00861">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00221">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="134"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="164"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="221"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD91255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="242" mass="25007" checksum="22C2CFD76F2EF454" modified="2019-11-13" version="1">MTPFIAEIIGTGLLILLGGGIVANCVLKGTKGSGSGWIEITTAWGLAVFVGVVVAGPYSGAHLNPAVSIGLAVGGLFPWADVPMYILAQMIGAMIGSALVYAMYKDHFDATEDAGLKRAVFCTDPAIPNNFRNILSEILGTFVLVFCVFYFSEASLNDGANTTVGLGSIGAIPVAFVVWGIGLSLGGTTGYAINPARDLGPRIVHALLPIKGKINSGWSYAWIPIVGPILGAVLAALLFLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPB2</accession>
    <name>A0A5C6ZPB2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Glycerol-3-phosphate dehydrogenase/oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_01330</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009331">
        <property type="term" value="C:glycerol-3-phosphate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004368">
        <property type="term" value="F:glycerol-3-phosphate dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006072">
        <property type="term" value="P:glycerol-3-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.870">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031656">
        <property type="entry name" value="DAO_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038299">
        <property type="entry name" value="DAO_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000447">
        <property type="entry name" value="G3P_DH_FAD-dep"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11985">
        <property type="entry name" value="PTHR11985"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16901">
        <property type="entry name" value="DAO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01001">
        <property type="entry name" value="FADG3PDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="6">
        <location>
            <begin position="22"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="DAO_C" evidence="7">
        <location>
            <begin position="413"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD91257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="525" mass="58654" checksum="80B7CF37EADEC3D5" modified="2019-11-13" version="1">MKMDRFKRETLIAQMKTNETWDAIIVGGGATGLGIALDCATRGYKTLLLEQVDFAKGTSSRSTKLVHGGVRYLAQGNIDLVREALHERGLMMKNAAHLVSNQSFIIPNYSWWDHFFYTVGLKVYDFLSGNLSFGKSTRIGKKETMARLPTIETAHLRGGVVYQDGQFDDSRLAVNIAQTAIEQGATLLNHFEVKQLLKNDAGIVNGVVAVDQETNETYQLKSKVVINATGVFTDEVLQMDNPSAKDQIKPSQGIHLVLDKSFLAGNDAIMIPKTDDGRVLFLVPWHNRVVVGTTDTVLDSHSLEPRALEAEINFILTTANRYLNKDVSRDDVLSMYAGLRPLAAPKDDSEKTKEISRSHKIIVSDSELITITGGKWTTYRKMAEDTVNRAIKMNKLPQKECRTKDLLIHGSSKPIAESNHLYVYGSDIMGIEALQQEHPELKERLHERVPFTKAEVVWAVRHEMARTIDDVLARRVRVLFLDAGAAIAMAPEVAALIAKELGRDKQWEAEQVKDFLKIADHFVCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZQW4</accession>
    <name>A0A5C6ZQW4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Bifunctional NAD(P)H-hydrate repair enzyme</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Nicotinamide nucleotide repair protein</fullName>
        </alternativeName>
        <domain>
            <recommendedName>
                <fullName evidence="16">ADP-dependent (S)-NAD(P)H-hydrate dehydratase</fullName>
                <ecNumber evidence="16">4.2.1.136</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="16">ADP-dependent NAD(P)HX dehydratase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="16">NAD(P)H-hydrate epimerase</fullName>
                <ecNumber evidence="16">5.1.99.6</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="14" type="primary">nnrD</name>
        <name evidence="15" type="synonym">nnrE</name>
        <name evidence="19" type="ORF">ESY86_01475</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 16">Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.</text>
    </comment>
    <comment type="function">
        <text evidence="14">Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.</text>
    </comment>
    <comment type="function">
        <text evidence="15">Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 15 16">
            <text>(6R)-NADHX = (6S)-NADHX</text>
            <dbReference type="Rhea" id="RHEA:32215"/>
            <dbReference type="ChEBI" id="CHEBI:64074"/>
            <dbReference type="ChEBI" id="CHEBI:64075"/>
            <dbReference type="EC" id="5.1.99.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 15 16">
            <text>(6R)-NADPHX = (6S)-NADPHX</text>
            <dbReference type="Rhea" id="RHEA:32227"/>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
            <dbReference type="ChEBI" id="CHEBI:64077"/>
            <dbReference type="EC" id="5.1.99.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 14 16">
            <text>(6S)-NADHX + ADP = AMP + H(+) + NADH + phosphate</text>
            <dbReference type="Rhea" id="RHEA:32223"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:64074"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.2.1.136"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 14 16">
            <text>(6S)-NADPHX + ADP = AMP + H(+) + NADPH + phosphate</text>
            <dbReference type="Rhea" id="RHEA:32235"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.2.1.136"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15 16">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="15 16">Binds 1 potassium ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="14">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the NnrD/CARKD family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the NnrE/AIBP family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 16">In the C-terminal section; belongs to the NnrD/CARKD family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 16">In the N-terminal section; belongs to the NnrE/AIBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.136" evidence="16"/>
    <dbReference type="EC" id="5.1.99.6" evidence="16"/>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052855">
        <property type="term" value="F:ADP-dependent NAD(P)H-hydrate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052856">
        <property type="term" value="F:NADHX epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052857">
        <property type="term" value="F:NADPHX epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046496">
        <property type="term" value="P:nicotinamide nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01171">
        <property type="entry name" value="YXKO-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01965">
        <property type="entry name" value="NADHX_dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01966">
        <property type="entry name" value="NADHX_epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017953">
        <property type="entry name" value="Carbohydrate_kinase_pred_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000631">
        <property type="entry name" value="CARKD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030677">
        <property type="entry name" value="Nnr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004443">
        <property type="entry name" value="YjeF_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036652">
        <property type="entry name" value="YjeF_N_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01256">
        <property type="entry name" value="Carb_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03853">
        <property type="entry name" value="YjeF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017184">
        <property type="entry name" value="Nnr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64153">
        <property type="entry name" value="SSF64153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00196">
        <property type="entry name" value="yjeF_cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00197">
        <property type="entry name" value="yjeF_nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01050">
        <property type="entry name" value="YJEF_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51383">
        <property type="entry name" value="YJEF_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51385">
        <property type="entry name" value="YJEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 14 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 15 16" id="KW-0413">Isomerase</keyword>
    <keyword evidence="12 14 16" id="KW-0456">Lyase</keyword>
    <keyword evidence="15 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 14 16" id="KW-0520">NAD</keyword>
    <keyword evidence="9 14 16" id="KW-0521">NADP</keyword>
    <keyword evidence="7 14 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15 16" id="KW-0630">Potassium</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YjeF N-terminal" evidence="18">
        <location>
            <begin position="9"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="NADPHX" evidence="15">
        <location>
            <begin position="58"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="NADPHX" evidence="15">
        <location>
            <begin position="131"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="504"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="326"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="377"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="412"/>
            <end position="416"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="440"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="441"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00009524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00025153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR017184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="TXD91283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="523" mass="57823" checksum="E6955BF54A366919" modified="2019-11-13" version="1">MKIFSKQQIYEGDKLTAKKQNITSTELMERAGIQIFNWLNVRMQGAQVPVHVFCGIGNNGGDGLVVARHLIAHGYNVNTYVVNYSSTRSKDFLNNYDRIKESTKKWPHMLDKDSDHPEIHKDDIIIDAIFGIGLNRSVDAWVKQLFQHFRKSEAFTLAIDIPSGLNVDKVPKDENDLVWANYTLSFQAPKLVFFLPETAKYIGQWEVLDIGIDIEYLSNTETAAELIGKNEVLSIYKPREKYSHKGTYGHSLIIGGSHGKIGAVVLSSRAALSIGAGMVTAFVPECGYQIVQTAFPEAMVLTDATETKITNITFDIEPSVIGIGMGMGTDAETTNALKQFLKHNTIALVIDADALNILSKHKELLEALPAKTVLTPHPKELERLIGKWKGDFDKLKKVKAFSEKYDCIVVVKGANSITVYKDKYFVNTTGNPGMATAGTGDVLTGVITGLISQGYEPLKAAIFGIYLHGKSADIAIENLGYQSMIASHIIESLGKAYIDLFQQPEPQQTEAEHAQEESPKQKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6Z9H4</accession>
    <name>A0A5C6Z9H4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">TSPc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000065">
        <property type="protein sequence ID" value="TXD86386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TSPc" evidence="1">
        <location>
            <begin position="250"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="486" mass="55475" checksum="F93D016F5284D15F" modified="2019-11-13" version="1">MKIRSIITIILLLPLSVFGQKELSNEQILEDYTIFKEILTVGHPSFYEYTSQVAWDSIFSSFEQKEIKGVKTPNDLFKSISSIAENVKDGHLNILHPKIDTLPTMFPILIKFIGGKLYTDTDDFGITVGSEIMSIDSKSTHTILKDMLKYAPSDGFNLTKKYLQIEKEFGILHYYEYGVKESYSVKYTTPEGKVKTIEISPKSFESIGNRYPNRNSHFASYHQNVNRVEYFKNRIAEEWPFVYYIDSLNTAVLTVNSFGLDPQEFKSKLIDLFKEIKKKKAKSLIIDIRQNIGGYRINAINLYSFLTNEPFKQRILESAITNVLPHEKYVVHTISNYTDFFGMYFTSAKKEDGRWMLTEDHAQAEMVPYKKTFNGNMYVLIGGNTFSAASAFALSAKNDKNITLVGEETGGGYYFHTAQYSALYELPNSKIMVRVPFVKIDKYVSDKSVPKGSGILPDKEVILTVEDLIKGTDSQLDYVVKHISNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAB6</accession>
    <name>A0A5C6ZAB6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AAA family ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_19110</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000036">
        <property type="protein sequence ID" value="TXD86866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="18"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="590" mass="67224" checksum="939C19323C465B40" modified="2019-11-13" version="1">MNKPNYILSKGQTIDEKYKVTFFLKKGSYAETYRVKDQEGKTKLLKLFAYSKLDRTQFNDKGDILEIEILKQITHPNLVKYSNNGKLLLENQKYAFVILDFISGETLAEKMKREQTFNTYEAKDIISGVLNGLNYLHNLENPIIHNDITNLNIMTDLSGKVTVPKIIDFGYARYLSQSNKDFLKEGLNPFYQANENFNKVFSVQSDVFSVGALYYHLLFGLPPWFVEISKYKSDKIKLEDAVLEERKKPLKFEKNIDEQTQNIITKALQPNSENRFKSIKVFIQAINGELGVQQLSSPQEKTKPKLKEIKNGQGFSAIAGMQELKDTIQLDVIDALNEKERYAEYGLTIPNGMLLYGPPGCGKTFFAERMAEEIGFNFYQIKPSDIQSKFVNASQENIKNLFDEARENAPSIIFIDELDALVPNRDNSSVNHMNTSAVNEFLAQMNNCGDDGVFIIGATNRPNSIDPAILRAGRLDKVIYLPPPDFEARELMFKLYLDKRPREVGLDYSVFAKATENYVSSDIKFLCDEASRKALKMKSRISKEILLETITNNRPSISLKELNSYIAIKAKMEGLAENTNERPSIGFKNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBQ1</accession>
    <name>A0A5C6ZBQ1_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 2">Peptidyl-tRNA hydrolase</fullName>
            <shortName evidence="1">PTH</shortName>
            <ecNumber evidence="1 2">3.1.1.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pth</name>
        <name evidence="4" type="ORF">ESY86_18475</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 2">
            <text>an N-acyl-L-alpha-aminoacyl-tRNA + H2O = a tRNA + an N-acyl-L-amino acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:54448"/>
            <dbReference type="Rhea" id="RHEA-COMP:10123"/>
            <dbReference type="Rhea" id="RHEA-COMP:13883"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59874"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:138191"/>
            <dbReference type="EC" id="3.1.1.29"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the PTH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.29" evidence="1 2"/>
    <dbReference type="EMBL" id="VORO01000031">
        <property type="protein sequence ID" value="TXD87043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004045">
        <property type="term" value="F:aminoacyl-tRNA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00462">
        <property type="entry name" value="PTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00083">
        <property type="entry name" value="Pept_tRNA_hydro_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001328">
        <property type="entry name" value="Pept_tRNA_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018171">
        <property type="entry name" value="Pept_tRNA_hydro_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036416">
        <property type="entry name" value="Pept_tRNA_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17224">
        <property type="entry name" value="PTHR17224"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01195">
        <property type="entry name" value="Pept_tRNA_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53178">
        <property type="entry name" value="SSF53178"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00447">
        <property type="entry name" value="pth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01195">
        <property type="entry name" value="PEPT_TRNA_HYDROL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01196">
        <property type="entry name" value="PEPT_TRNA_HYDROL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD87043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="188" mass="21017" checksum="4D24EC22137C579B" modified="2019-11-13" version="1">MKKFLIVGLGNVGAEYANTRHNIGFKILDALAEAESLSFTTEKLGDIGTYKFKGRTFILLKPSTYMNLSGKAILYWMNKEKIPLENLLIVTDDLNLPFGTIRLKTKGSDGGHNGLKDTQDKLQTTNYNRFRFGISDEFSKGSQVNYVLGEWSEDEEKDLKDRLEKSIALIKSFGTAGINNTMNAFNGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBQ5</accession>
    <name>A0A5C6ZBQ5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19395</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000039">
        <property type="protein sequence ID" value="TXD86773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="99" mass="11713" checksum="BF7855515C6F557C" modified="2019-11-13" version="1">MKHNPSQREDVGGKHQYRQLNHEQNSTQIYVFKTYCLENKQAFFNRDSRFSTAIVGVFHQQSQQSEEKAHIKYQMQIQTAKPLLVFSTNNPSRVRRKLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBT8</accession>
    <name>A0A5C6ZBT8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17565</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000027">
        <property type="protein sequence ID" value="TXD87242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="6"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="312" mass="34732" checksum="2F6048AE8A1ADCB1" modified="2019-11-13" version="1">MKKVGIIGGSGFIGSHITQRFLENGFEVKVSATDITKQEKYEHLMELNHSDHLYISELNVENKAQLKEFVKDCDIVVHGGTPFQLDVKDAKSELFDPTIKGTENFLEVINETPTVDKVVLIASVAAWNTNFPFPAGGRISSDTFSEKNTAFMSDESHPYAQAKFIANQTVNDYIKTHPDLDFEITSVSPVGVFGKSLSQREDSVSTGLQYLIKNNLAPNPYIQMFYDTDVEMAIVNVQDVATAIYKAATISGLHGRNYLLSSETYTISDVSLMLNGKPPKHPAKIIYQNQKAERELGQSFQSVMDTLNQYSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBU8</accession>
    <name>A0A5C6ZBU8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">Peptidylprolyl isomerase</fullName>
            <ecNumber evidence="2 4">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_18675</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="2 4"/>
    <dbReference type="EMBL" id="VORO01000033">
        <property type="protein sequence ID" value="TXD86953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0697">Rotamase</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023050318" description="Peptidylprolyl isomerase" evidence="6">
        <location>
            <begin position="21"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase FKBP-type" evidence="7">
        <location>
            <begin position="130"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="248"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="255"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD86953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="318" mass="34654" checksum="47290EEAD2B54C5C" modified="2019-11-13" version="1">MKYLKYSLVLFLTLAMGSCANDDDAPIPVVPPRDRGEQQIEDDMALVNYLESHYYNASLFETPGDYEITDIEIMELPKDADGNYLALPNPDTNKILKDVVETKNTTFAETSYKYYILRINQGGGDSVNFTDALRLNYAGSLEDGTVFDSAINPILINLVGNGSTTFGAIQGWKEVMPSFGTAEGDAVINDDGTVSYNNYGFGVMFLPSGLGYFNSSVASIPGYSNLIFKFAIFEAIADDLDRDGVPSHLEDLNDNGDLMDDDTDGDGIPNFADVDDDGDGVQTQFEDLDNDGDPTNDDSNGDGIPNYLDPESTETNQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBY4</accession>
    <name>A0A5C6ZBY4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">WYL domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_16735</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000023">
        <property type="protein sequence ID" value="TXD87539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026881">
        <property type="entry name" value="WYL_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13280">
        <property type="entry name" value="WYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WYL" evidence="1">
        <location>
            <begin position="118"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="298" mass="34845" checksum="3525108539968592" modified="2019-11-13" version="1">MSLDIRRYLVILELLKNADGLLTSQQIAAGLKREGIIFKSSTFSRDYQFLVGLGFKIHNPKTKGYKIEIEDTEEFSFLTNLFKRIALSNLLNKSITLENETHKYLSLDDTSLVKNFQYFDLILEAIKNRKELSFEHSSFYHTGRKEPKTHTIKPQLLKEYQNRWYVVGETENGFRVFGLDRLSDLQVLDNKPFRNKTEEANEKLSHTVGLNFSDYEPRHIVLRFDVSQKPYLESLKLHRSQEELTNGSNGFYTVKLFVSYNFELKQQLLKYGSLVQVLEPDFVRADIKAELEKAFKAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC11</accession>
    <name>A0A5C6ZC11_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Deoxyribodipyrimidine photo-lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_17320</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the DNA photolyase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000026">
        <property type="protein sequence ID" value="TXD87321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901363">
        <property type="term" value="F:heterocyclic compound binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097159">
        <property type="term" value="F:organic cyclic compound binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051716">
        <property type="term" value="P:cellular response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036134">
        <property type="entry name" value="Crypto/Photolyase_FAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036155">
        <property type="entry name" value="Crypto/Photolyase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005101">
        <property type="entry name" value="Cryptochr/Photolyase_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002081">
        <property type="entry name" value="Cryptochrome/DNA_photolyase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018394">
        <property type="entry name" value="DNA_photolyase_1_CS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006050">
        <property type="entry name" value="DNA_photolyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455">
        <property type="entry name" value="PTHR11455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00875">
        <property type="entry name" value="DNA_photolyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03441">
        <property type="entry name" value="FAD_binding_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00147">
        <property type="entry name" value="DNAPHOTLYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48173">
        <property type="entry name" value="SSF48173"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52425">
        <property type="entry name" value="SSF52425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00394">
        <property type="entry name" value="DNA_PHOTOLYASES_1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51645">
        <property type="entry name" value="PHR_CRY_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0157">Chromophore</keyword>
    <keyword evidence="3 5" id="KW-0274">FAD</keyword>
    <keyword evidence="2 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Photolyase/cryptochrome alpha/beta" evidence="6">
        <location>
            <begin position="7"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD87321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="490" mass="57826" checksum="504FC7771DE25741" modified="2019-11-13" version="1">MNTDKEHINVVWLKRDLRLEDNEAIVNALQSNKRTLLLYTFETMLMEDEHYSARHWDFVRESIRDLNVLLKDYNSKILAVEADIISAVNQLLTQFHITDIFSHQETGILLTYNRDKSFKRFCKNNLITWHENLNNGVQRGLQNRDQWMAQCNAYFEIEPLTFAPKDAQLVTTEAIEAVEFLFTIPSLETSAASPFQKGGRSMGLKYLNSFFESRYVNYMFHISKPELARTGCSRISPYLAWGNLSIREVYHRAYHLKKTSQNKQALEAFMSRLRWQSHFVQKFEMEHTMEAESVNKGFQKLKKEISESYQEAWRTGQTGFPLVDACMRCLNETGYLNFRMRALVVSFFTHNLWQPWQDASKHLSRMFLDFEPGIHYPQLQMQAGETGTNMLRIYNPVKNSLEHDPEANFIKKWVPELADLDTPFAHEPYLMTEMEQQFYNFELGKDYPYPIVDLDSTRKKASDTLWNLRKNKKVREESQRILKKHTLRNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCE0</accession>
    <name>A0A5C6ZCE0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Addiction module protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19205</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000038">
        <property type="protein sequence ID" value="TXD86784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013406">
        <property type="entry name" value="CHP02574_addiction_mod"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09720">
        <property type="entry name" value="Unstab_antitox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="75" mass="8702" checksum="4BED5BCEA5073CDF" modified="2019-11-13" version="1">MDIKAEKIELMKLLLDVENEGSLAELRAVLIADNEAHKLSSAQETELDYRLKRYESGETKFYSWEEVEEKLKAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCI1</accession>
    <name>A0A5C6ZCI1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Toxin HipA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18015</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000029">
        <property type="protein sequence ID" value="TXD87124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017508">
        <property type="entry name" value="HipA_N1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13657">
        <property type="entry name" value="Couple_hipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03071">
        <property type="entry name" value="couple_hipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Couple_hipA" evidence="1">
        <location>
            <begin position="5"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="104" mass="11666" checksum="D290930D7D451056" modified="2019-11-13" version="1">MRRAIVFVHGKRAGILTELSANDYSFNYDEHYESAAVSLTMPTSHKKYSYKSFPPFFEGLLPEGVMLEGLLRIGKIDKKDYFSQLIATGNDLVGSVTVKLSDNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCI8</accession>
    <name>A0A5C6ZCI8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">T9SS type A sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_18075</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000029">
        <property type="protein sequence ID" value="TXD87134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1064" mass="114655" checksum="83FF2F47301B9FC3" modified="2019-11-13" version="1">MIMNSKITYQTFLKFKGLTIILLLLSTTGLIAQTVTNVFPTRVTTKSTIIVSGAGFTSGTTVNLTGIAINNFSVVNANEIKFEVSFTGSADVVANLIVGGTDSNIDIEYVAPTPKTLRNGPTSNVTKVTEIFTTYNGFWRSSQWKADPNNQDLKPNTRHDLLAFTYDGVTYSTGVDDALLTTNGVAFSTQLFYAYTTNGVDGITQSQNYIAMADLIDGQENEGNTITSPEILGATIYDVLIDGVNGLDIGTGVTNFNQTSDVQFYSSGGQLGAINDDIPDFLISQIASAGSTDIYYYADSQENVVGRPIKLTILQENESDGDALLAEWRLDLYNLTSGTNYGVATPQSLAFSNSEERPLRMAAFTFENFEITPANIEAINNINMVAGGTADLAFLAYNRGSFDIKTPVVTQFPVSRNVCKIPSAADITLVATAAVSGGATGNPEEDLSYQWFKYNDPIPGATSNSYTISGAVNLEDLALYRLKVTNDFGALIVPATITQGGTPVFWNGTDWELPPAYTAAGITTVADEERGLVFTENYNQAGDLEGCDCTVPAGNQVIIPSGSTLKLYNTVKVANGASLTIKDNANLIQTKEVSTNANTGNIRVEREATDLHENDFVFWSSPVNGFDVSGITSPYASTAFQWDVNAANTEGTVGDWVPTSGVMTAAEGYVVQVPTEYVASGFTATFLGVPRNGTIAVEVSKSVGNTQPSLETRHWNLLGNPYPSAINADQLLDENGNLEGHVRLWSHDTEISNSSNPFYTGVVYNYDNDYVTYNATGATPPNTFEGNIASGQGFYVQVLESAAATSNVTFSNALRYDANEEAYDNSTFFRNTDASAAAMDDTDKELIWLSLVDASNVSSSALVGYVNGATEGKDRLYDTYSEDAAFSLFSLIGSSKMNIQGRSLPFSAEDTVPLGANIPQDGTYSIGIDMLQGATFVGQEQGIYLEDSLLDLEHDLRASPYSFTAEAGTISNRFALKYVAAPLSVNDNTYADTFAFVIHNELQIKSAVSIKAVQIYDISGKNLKSYAPERNTTHFKDEFQFSKGVYLAVITLDNEVKLTKKLIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCK4</accession>
    <name>A0A5C6ZCK4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Class I SAM-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19315</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000039">
        <property type="protein sequence ID" value="TXD86759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="60"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="231" mass="26226" checksum="8A25E536D41ABF52" modified="2019-11-13" version="1">MKDLFGNALRDYHNNNYTEDLVTSTNISDKDDLPLPYLFRSFVEMPKLEQKALQLAKGQVLDVGCGAGSHSLYLQQKGLKVKAIDYSKGAVEVAKARGVLTVELKALLDETETFDTILLLMNGTGIFQELKQLSTYLKHLKSLLKPNGQILIDSSDIQYMYEDDDGGLWIDTNAEYYGELDYFLSYKGEEELPMKWLYLDFERLNLACESVGLTCEKSTEGEHFDYLARLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCR0</accession>
    <name>A0A5C6ZCR0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Hsp70 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_19095</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000036">
        <property type="protein sequence ID" value="TXD86863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="PTHR19375"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="SSF100920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="707"/>
            <end position="746"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD86863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="840" mass="93620" checksum="392967BE81DC20F3" modified="2019-11-13" version="1">MTRTKIDYGIDLGTTNSAISRMENGEATIKKTDTLKDTMPSAVYINKKKAIQVGDSAYNALKRDKLRAMKTWNDSDSNSYIEFKRTMGSDKSYSSSNLEKDLTSEELSAEVLKTLKSFVKDESVNSIVITVPAAFKNNQKEATREAAKLAGFDHIELLQEPVAASMAYGLDSDKKDGFWLVFDFGGGTFDAALLKVEEGIMKVIDTEGDNYLGGKNLDFAIVDVIIIPYIQETFVIDSVLADDTKKQILRNAMKFFAEETKVALSFKETHNILSDLGDLGEDDEGEEIELDITVTQTDISNALSPVFQKAIDVSKNLLERNNLKGSSLDSLILVGGPTFSPVLREMLEIQICKPDTSADPMTVVSKGAALYASTVDVSEEVREQTRDKTKIQLEIANESSTVETEEFVPIKILADKTKGEIPKKVFAEVTRGDKAWSSGKIEINTIGEIVEIQLNEGKTNIFYVVLYNDKGDILESEPSNFSVIQGSKIGSATLPYNFGIELKDKSTGKVRFKTIKGLEKNQTIPAVGTLNGLKTQNQIRPGMDSDFIKIPVYEGEHASEGTRAIYNEHVTDILISGADLPSLLPENQDVDLTVNIDRSEKITVTAYFPYLDYTTEIEVDSTKTSIETTWLANEIRKAKGSVTELMQEGNSDVGKLQKIESELKKLEKSFENNKNDVDGKQEVLTNLRKSLKAIDELSETTEWPKLEEELKEEFYKLEKANSDLGNEKTNQLVNQLRSQLEEVIKAKDVKIGNILLEEINRLFFDLTFIYQLIGMLRNFNENFGNYSWKDSNKARQLINSGISKISENPDAEELRQILISLFNLLPQDEVPSGDNNVLVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCU0</accession>
    <name>A0A5C6ZCU0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Erythromycin esterase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_15545</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007815">
        <property type="entry name" value="Emycin_Estase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05139">
        <property type="entry name" value="Erythro_esteras"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="383" mass="44852" checksum="59E47CB1D25774A8" modified="2019-11-13" version="1">MKKTTALLFIVFGLNSILAQVEKNIYELNPIENLLTKDVKDILDSNLNGKKVVFLGESNHYFGSDLLAKTEFVKYLVLEKGYKDIAFEGDFLGLYFDHNKRNLYPFWSNSVQCKALFEFLKAHDVSIWGFDNQMNATYTYTDFTIKLNGFLNDNSISVDKRFIELTETFFKNTARSKSVEIVGKSNLEYLIVEIDKLLKNDTLIQDKLWTRFLESYKSYIMISSAHKSSKGITAIRDNQMAKNLDFLFKTMPEKKFIVWLHNAHMIKDDYGTQPGQTMGFQFVKANPNLSYHIAFSSIHMPYRKPKWIEKYSKDEGNLLHFLPTTEKNYFIDAQQIIRERPEYEAQEYDGMFIVENKDIKTNWFMHYDALVFISKGEDVKFIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD95</accession>
    <name>A0A5C6ZD95_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_16795</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000024">
        <property type="protein sequence ID" value="TXD87437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="12"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="177"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="357" mass="39802" checksum="A7EBE91E890D37A4" modified="2019-11-13" version="1">MRVLQLIDSLEAGGAERMAVSIANTLSESIERSYLCATRQEGLLKASLKPEVSYLFLNKTAKIDSAAIMKLKRYIKQEQISIIHAHSTSFFMATLMKLLRPGLKIVWHDHYGNSDYLEARQYKMLRLCSQYFSLILSVNSVLETWAKNHLKCERVSYLSNFATADAAQVLQTELKGTPGKRILCLANLRPQKDHPTLLKAFEIVNSHHPDWSLHCVGQDFEDAYAHSVYELVSQLQLQEQVFFYGSCPDSSAIIHQADIGVLASASEGLPLALLEYGLGGLPIVATNVGDCSSVLPKTLHEFLVPANSPEPLAKQLMVLIADADKRQQIAKLVKGYVLKEFSALAVRDKLMTFYDSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDE0</accession>
    <name>A0A5C6ZDE0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uracil-DNA glycosylase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18265</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000030">
        <property type="protein sequence ID" value="TXD87078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005122">
        <property type="entry name" value="Uracil-DNA_glycosylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03167">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00986">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="SSF52141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDG" evidence="1">
        <location>
            <begin position="25"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="190" mass="21973" checksum="18E51FBBC5AFEC1A" modified="2019-11-13" version="1">MESLIQEIRQCRICKAHLPLGPKPILEAEKNSKIILLSQAPGRVAHQSGIPWDDAGGKRLREWLNVSEEQFYNTKNFGIMPMGFCYPGKGKSGDLPPRPECAPQWHDLLWKEFKQVELVILIGMYAQKAYLKKQAKRTLTETVATYEEYLPRYFPLPHPSPRNRFWLSKNPWFEEEVLAVLRARVKGLVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDN0</accession>
    <name>A0A5C6ZDN0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17225</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000026">
        <property type="protein sequence ID" value="TXD87304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022753233" evidence="1">
        <location>
            <begin position="19"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="496" mass="56192" checksum="3D853061212ECDC4" modified="2019-11-13" version="1">MKKFLLLACFIAVSAAYSQTTTKLSVSESEEYKDEVKAKDILAIHTTNSGLTGIIRDSKRDFLFDVFDTGLNKVFNMVVESDRNETFVGELFSGEEMKFFTVDSPKKTERIIYCHIFNLAQKSVKKVKLFETTVEKKQALFSGGNKRETSFAISPSGNYFAVTTDNSKKHANAYTIRVFDASNLSLLFEKVYQEHEERYYEHNDLSIDDEANVYALGKLFVKGRSQKKDGEANYEFVLNKISKSDMKAISIGMDEEHIQSLNISVTENQLNLLGFYSEERAGRIKGGCNFTIDKKELAITSKKHQDLPIAVYEDLYGDKRADRKKDKELTSFYVDYVLTDDDDNTYMLAEEFYITTTYVSMGMNGGHIQTVNHYDDVLVFKFDNSGNLAWGRSIFKRATAPSYNAFVKNNQLHVILNSGKNLLEKNDGRTKVSKGFLESSSLYDIVYSADGDVSYDKIQDNKGNTDYVPFFGTFETGTFIMSSAGGGRNNQFMILK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDN7</accession>
    <name>A0A5C6ZDN7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TlpA family protein disulfide reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_14585</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="17"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="156" mass="17885" checksum="5822BDA7DEA2260C" modified="2019-11-13" version="1">MFSSEGFAQDKQLWARSYINKKAPALKLDKWLTEKPDTEGKFIMLDFWATWCGPCKREIPQMNAYSEKFKESLVVIGISAETEEKVKRMTTPKINYYSALDTSKIMNTVYGIQGIPHVVLIDPEGFVRWEGFPTLANHKLTAGVISKIIKDYKTKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDP1</accession>
    <name>A0A5C6ZDP1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hydroxyacid dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_18810</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000034">
        <property type="protein sequence ID" value="TXD86921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2-Hacid_dh" evidence="2">
        <location>
            <begin position="29"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="2-Hacid_dh_C" evidence="3">
        <location>
            <begin position="105"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD86921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="311" mass="34584" checksum="41C1E54161D2AA64" modified="2019-11-13" version="1">MKILHLDTNHPLLIQQLNALGFENDEDYTSTKALIQEKIHLYDGFIIRSRFKIDSDFLDAAKNLKFIGRVGAGLENIDTLHAEKKGITLIAAPEGNRNAVGEHSLAMLLSLFNKLNKADAEVRQGHWLREANRGIELDGKTIGLIGYGNTGKAFAKKLRGFEVNVLCHDLKPNLGDEHAKQVSLNELQERAEVLSLHTPETDLTVNMVNSHFINAFKKPFWLINTARGKSVVTANLVAALKSGQILGAGLDVLEYEKSSFEHLFSSEMPEAMRYLIEAENVILTPHVAGWTVESKEKLAQTIVDKIKSSFC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDQ1</accession>
    <name>A0A5C6ZDQ1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000034">
        <property type="protein sequence ID" value="TXD86931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012544">
        <property type="entry name" value="PHb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037063">
        <property type="entry name" value="PHb_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08000">
        <property type="entry name" value="bPH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="bPH_1" evidence="1">
        <location>
            <begin position="2"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="91" mass="10484" checksum="E88CEF8EC464BFD9" modified="2019-11-13" version="1">MGFTLFRDVFMFTDKRLIIIDVQGLTGSKIEYKSMPYKNTSRFSLETSGAFDLNAELKIWISSEDLPLVSKKCNKSSDVYEVQRYLAARVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDV1</accession>
    <name>A0A5C6ZDV1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_16025</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000021">
        <property type="protein sequence ID" value="TXD87664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1148" mass="130604" checksum="E32AC9EF2F40843F" modified="2019-11-13" version="1">MKQEIQDKKPVELKNVKIDGQSYFKITNHDEMRPFFMSIVSDANHWLFVSSNGGITAGRKNSEYALFPYYTDDKITESVEVTGSKSIFAIETKEGRKTWEPFSIRNEGLYKITRNLYKNTFGNKVIFEEENHDLNLTYSYQWSSSNTYGFVKTSKLINTSASEQKVSVLDGLQNILPFGVPSETQMRVSNLVDAYKRSELVEEAGLGIFALSAIIVDKAEPSEALKANVAWSLGLDHVKYLLSSKQVADFRQGKAITQETDIKAEKGAYFINTEMSLQPNAEKEWMIIGNVNQNHSAIAALVQDIKSNKQLAANVRSDIEKGTENLYKLNAGADALQLTADKLRDTRHFANTLFNIMRGGIFDHNYQIEKWDFKNYISKANQEVYSNVSDVLNDLPETFDLSKLKGMAGSSDDMDFKRLCLEYMPLKFSRRHGDPSRPWNKFSINTTNEEDGSKILDYEGNWRDIFQNWEALAHAYPEFIESMIHKFLNASTFDGYNPYRVTKEGFDWEIIEPDDPWSYIGYWGDHQIIYLLKFLEFIESHEPGKLESYFNRSLFVYANVPYRIKPYQEILKNPKDTIDFDMDAQEQIEADRLKLGADGALLKSKENTIYKVNFIEKLLATVLAKLSNFIPEAGIWLNTQRPEWNDANNALVGNGVSMVTLYYLRRFLHYFEGILAKADVQEVHISEELLIFFNGVYAAFKNHESLLNAAFNDTQRKAVLDQLGASASDYRMAIYKDGFSGKKQSLKLDELSALVMISLKYLEHSIDANQREDKLYHAYNLMTVESEQSISISHLEEMLEGQVAALSSGYLDSKTCLDVLDAMKSSKLFREDQYSYLLYPNKGLPGFMVKNTIPKEAVDQSQLIKKLDEKGNTSIVEKDVNGDFHFNGNFNNADSLKKALSKLKSTEFKELAEQETQLLLTTFEKVFNHKAFTGRSGTFYGYEGLGSIYWHMVSKLQYAVQEVCLRAIREKQSDAVVGSLLEHYYEINEGIGVHKSPELYGAFPTDPYSHTPAGKGAQQPGMTGQVKEDILSRIGELGVFVNEGKLNFNPCLLRTNEFLTSSRVYSYIDVAQNTNEIKLNAHMLAFTYCQVPIIYHLGNKIGIELVLVDGASKTYDSLSLDEVMSSHIFKRNHKVKQVNVYVTEGICN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDV6</accession>
    <name>A0A5C6ZDV6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">SusC/RagA family TonB-linked outer membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_14800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023996">
        <property type="entry name" value="TonB-dep_OMP_SusC/RagA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023997">
        <property type="entry name" value="TonB-dep_OMP_SusC/RagA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04056">
        <property type="entry name" value="OMP_RagA_SusC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04057">
        <property type="entry name" value="SusC_RagA_signa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022982112" evidence="5">
        <location>
            <begin position="23"/>
            <end position="1067"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="7">
        <location>
            <begin position="115"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="6">
        <location>
            <begin position="449"/>
            <end position="1066"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD87935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1067" mass="117061" checksum="CE3326B17520FCA1" modified="2019-11-13" version="1">MKTKFSGILTLLLVFVVQISFAQEVSVTGKVTDENGMPLPGATVVIQGTTTGASTDFDGNYAINASQGEVLEFRYVGYSTKSITVGASNVINASLALDNTLDEVVVTALGISREKKSLGYSTQQIAGEELTETRNATALNALSGRVAGVQISTPSGNLGGSTRILIRGIGSITQNNRPLIVVDGIPLDNSNYNSNSAQTGGGGTDFGDTGFDINPDDIASMNVLKGGPAAALYGNRASNGVIIITTKTGKKGKGEIVLNSGVSFETINVVPQVQKLYGGGGGIASTFEQSDFNSVNINGQPFDIVDYATDESWGPRYDPTRSVLHWDAFDPEFPNEFLQPRAWVYPKNDREDFFNTGVSVNNGVSFSSGTEKGQMRLSINNTQQTGIVPNSELDKTSFNFNGSSKITEKLEVSAGINYTVTNGFNRPAIGYTGAGVIQQFFQFGQTSVDMERLKQYQLPDGTQRTWNRIAYDNPNIRYSDNPYWTINKNVTTDKRTRYFGDVGMKYNFTDELYVTAKIYSDTYDDRRSSRTAQGSAEQSLYTEVDRDFSETNYEAILFYDTDIANDRISINSFFGTNKRVSSFQSLDGSTNGGLVVDGIYNLNNSVANPFVNDFDSRRQIESVFASASFGFDDTYYLTVTGRNDWSSTLPEANNSFFYPSLSGSVVFSEFFEADWFTFGKIRGGYAEVGGDTEPYNLRNAFASNPAFFDGIRFTQPSQNNNPNLRPENKKTWEVGLEMGFFKNRVNMDLTYYNERTEDLITPVQVDPSTGYTSTVANAGVLENKGFEALVNITPIRTDDFDWTVTWNFAKNDNELLELLPGVNSLELARFPFNGVTLNAIVGQPYGIIRGTDFVYDDNGNKVIKANGLYAETVTQQNLGSVLPDYNMGFRNSISYKNFDFSFLIDVQKGGKYRSLTNIWGHYSGILESTAANNIRVEGVVLEGVTGTIDYNDDGSYTVTNTAENTQAVPAQRWGQDHFFGADALNVFDADYVKLREVALGYTFPKKWTGDVASIRLSAFGRNLFVWGLDNENFDPEVATSGSGNIQGSEGGSLPSTRTYGLNLEIKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDV7</accession>
    <name>A0A5C6ZDV7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000036">
        <property type="protein sequence ID" value="TXD86858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022700110" evidence="1">
        <location>
            <begin position="20"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="298" mass="33861" checksum="7AF227AAADA33EBD" modified="2019-11-13" version="1">MLKTLSILVLVSVCEMSFAQDEALFNRLRAIENGGITFFNVDGIDFTKETLYSNFNEKNLKKAYRKYKIKKKDEKEIDRALDFDNYRVITRETFDEGLVSVSVNYFVKNKDNFIDVFWFGYYEAQNPAFERKMIALISNDKIPKSCFSAMQTDTINFAGRAIALGGNCNWMNINNIQCPYYGQMNWSVHDTKASADLFIQNQLKATKIKNGGKVISEVVVDIVFEGVPTQAKKVYYDFTGVTSLLASMSGGKNLTIYYVSEKIRGNYLSCVLSFWNNDSINPSGLPALLEKVMTIAEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE20</accession>
    <name>A0A5C6ZE20_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15375</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022867039" evidence="1">
        <location>
            <begin position="21"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="492" mass="55147" checksum="2D26C2466F40610B" modified="2019-11-13" version="1">MKATKFFLLCMITLALTACSKEENKRFSNADGPFVRFFLLVNNNNEALEFPEINGGLQPVSVFDKTDIKILKIPVALTYEALSENITVNFESTSSINMSNFNISPNNLSFTPERLIDTIYVGFNERWNPNANTELNFRLTNVSDQNIQIGMPNNDASNETLLVTLGEVNPTYLFETPNQQEIIGTNGEVINFSVLFPKGYLPSELENFNLIEAINSDFNYTLERLPLTNTSTIDYKLTLNEAITIDELEFSAQFKLADLSGYTLSGSSTYSIKKPIVIDRDLSVFTANNFYDLSDPFYRTFGENWIDNSDDGVCEWRSFNAFTFPVVVTADNPNAVLYDDMGNSDSSDDIYHHAFRIGFVSPNDGNTTNSFNLKRWFNNEASNSSNSPGFNIPQALEFFPTNGNSSSDGFVKVIEQDLSISSLEGASYVISISGSGTYTEIATGIFEIQLELNTFNLELFGGTRTVYYHIYNTNEYEELEPISESCFAPIDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE50</accession>
    <name>A0A5C6ZE50_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_17135</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000025">
        <property type="protein sequence ID" value="TXD87393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="143" mass="16792" checksum="BF7DC497AE81C41A" modified="2019-11-13" version="1">MTFEDSKYSKLIPYKKVQFPFGTFYLTKHFTISEFNEGVHVDYAIASDIISHFSEEIKRGFKIGYIANRINSYSFDLQLWKEVSDDYDFLVASAVVSYTNFNHLNASLEKHFSEKSLKRCKSLDEAIKWILDLKEFKNKCKTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEV1</accession>
    <name>A0A5C6ZEV1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">LuxR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_16070</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000021">
        <property type="protein sequence ID" value="TXD87687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011110">
        <property type="entry name" value="Reg_prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07494">
        <property type="entry name" value="Reg_prop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="728"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="4">
        <location>
            <begin position="871"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="769"/>
            <end position="808"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD87687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="931" mass="106827" checksum="A864F752FE2123C8" modified="2019-11-13" version="1">MLTLFLIFIGLASVTGQELPPIESFSTEDYRAENQNWAISQTANKFIYVANNKGLLEFTGADWKLYPSPNQTILRSVHAVGNRIYTGCYMEFGYWQPSADGHLRYTSLSENLALGMVEDEQIWNIVSLDNYVVFQSLNRIYSYNLDSQTFSKIEAETTLTKMIKADRTLYFQKYNQGLFKIESGVEKLVSNDAILKSNIIVNIFSRSGKLIIQTKTKGFFVLEDGQLSKWDIPANDYISGLTVYSSICLNDGSLAIGTISNGIVHLSASGEFDYRLNQDQGLLNNTVLSLFEDSDENLWLGLDNGINCINSASPYRIYKDKNGRLGSIYTSRIYKDILYLGTNQGLFFKPFDSDQPFELIEATKGQVWCLTVIDDRLFCGHDSGTFEVEGTSVRQITFSEGTWDLKPIPNHDDLILQGNYNGLNVLERKNGKWSFRNKLTGFDMSSKYVEILDADHIFVSHEYKGVFRLEVDGTYHKVENFKNMESVSKGLHSSLSTYENDIFYASNRGVFKYKLEENVFLKDSILSESLNTETYKSGKMVTDGTGKLWFFSENNIFYVTPGHLSETPKVTKIALPSTIRNSISGYESIMHTQGQNYLFGTSSGYIMIDLDKVKEQVYNIKINSVHNYTTDTDANKNLVAINETNEFTIKSNNFAFAYSIPEFDKYLESEYQYRLNGDYDQWSNWSKSYSELFKNLAFGDYTFEVRGRVGNTPTENTATYSFSIAKPWYISNLLIFIYILAVLLFSILMHNVYKRYYKKQKSKLIFANKRDLELKELETEQQLMQLKNEKLQQDIENKNRELAISTMSLIKKNEFLNSIKEELKSSETGKGLKSVVKIIDKNINNTDDWKFFQEAFNNADKDFLKKVKSIHPKLTPNDLKLCAYLRLNLTSKEIAPLLNISSRSVEVKRYRLRKKMDLPHEASLTNYILEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF22</accession>
    <name>A0A5C6ZF22_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15880</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="1">
        <location>
            <begin position="2"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="312" mass="36821" checksum="0CCBAA396D024F90" modified="2019-11-13" version="1">MIDLIGDVHGYADELEELLTKLGYSKKDNYYSHPNPNRTVLFVGDYIDRGPKIRETLEIVKQMVDNDSAIALMGNHEYNALTFHFKDPKGGHLREHSIKNILQHYETLYQFRNRVEVPDGEKEYEEYMEWFKTLPLFYETETFRAVHACWDYKSIDYLKKHLQNNRLTDDLIRESAKKETELYEAIEDTLKGKEIKLPEGGEFKDKDGNEREEMRIKWWVDPSGMTYKTISMPTNDKLPEEAVYLKDKDYYKKDDKSVFFGHYWLKGKPSLYQDNICCLDYSVAKDGILAAYSFDDELILDEQKFTSVEKIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF61</accession>
    <name>A0A5C6ZF61_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipocalin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024311">
        <property type="entry name" value="Lipocalin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13648">
        <property type="entry name" value="Lipocalin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipocalin-like" evidence="1">
        <location>
            <begin position="29"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="156" mass="17452" checksum="5EDFB1638C79CE3A" modified="2019-11-13" version="1">MKNALLAVTLVCLFSCGGSKVVRESEKTIKGNWNLNSITYSKTGDYDVTLLNDTSKDCFENSTWQFVPNNNTGTYSIINADCNTGDRYFNFDIEEADATTGLYDFMLKPTNEKGKSETDAGFRMKLTAISENSMQWQQTVISNGAPFIINMNFTKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFB8</accession>
    <name>A0A5C6ZFB8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6 9">50S ribosomal protein L22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rplV</name>
        <name evidence="10" type="ORF">ESY86_14855</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="5">This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="6 9">This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6 8">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the universal ribosomal protein uL22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00336">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01331_B">
        <property type="entry name" value="Ribosomal_L22_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001063">
        <property type="entry name" value="Ribosomal_L22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036394">
        <property type="entry name" value="Ribosomal_L22/L17_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005727">
        <property type="entry name" value="Ribosomal_L22_bac/chlpt-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13501">
        <property type="entry name" value="PTHR13501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00237">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54843">
        <property type="entry name" value="SSF54843"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01044">
        <property type="entry name" value="rplV_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 6 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 8" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD87946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="135" mass="15196" checksum="88D737F927A4C5B7" modified="2019-11-13" version="1">MGSRKKQMADAIKEERKHIAFAKLNNCPTSPRKMRLVADLVRGKEAEKALQILRFSSKEASRRLEKLVLSGIANWQAKNEDASIEDADLFIQEIRVDGGAMLKRLRPAPQGRAHRIRKRSNHVTVVIGAKNNTQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFC6</accession>
    <name>A0A5C6ZFC6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">CBS domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_14685</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="218" mass="24906" checksum="3249591A998F927B" modified="2019-11-13" version="1">MPLEQYLINDIKPLDYSAKVSDLKMMFNELTYSHIPITKEGIYMGCISETDAHCFEGKQAIEECSHSLEGFYVRDTSNWLDALEAFAQNSCNIMPVLNAQNQYLGYYELNDVIGIFNETPFFAEPGGVLIIETTTQDYSFSEISQIVESNDAKLLGAFISKMESDIIQITLKIGETGLNDVIQTFRRYSYNIISGHEDDTYVENLKERSEYLKKYLDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFD7</accession>
    <name>A0A5C6ZFD7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_13575</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018297">
        <property type="entry name" value="A/G_cyclase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00452">
        <property type="entry name" value="GUANYLATE_CYCLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="368"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="3">
        <location>
            <begin position="438"/>
            <end position="568"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="620" mass="70065" checksum="3884F36D8E4967B8" modified="2019-11-13" version="1">MDKRRHLIWLRLLIAVICVHSFNAQDKSKIDSLETSYLTQNLSIPEQMAILSELANKHPNPSQSLLYSDKLLVLAQSQNSTKNIINALQQKGNALTIKGNLSQALEIFMDGVQLAKEEKEIEMLGGFYISIAGVYSVMDNKSHTILYYKKAIEVLKDLDDKSNYAAAIENLGDEYNLNMAKPDLALVYFEESGKLWEQLGRKAGLAYNIGNKGLAYAQLKRSEEAESNITEAIRMLEELGDYYGISVYLTYMSDIYIEKGDYEAAISYANNSLALAKKYGLKDQIADAYLKLSELNEFKGRLRPSLDYYKNYITYRDSVKSISEAQAIAEIKRDRDLAQAEFTRERDLAVKDQELALSEEKVHNKQNVAIGIGVALFLIALLALGLYRRTMYISKTKKIIEIERNRSDKLLLNILPEQTAIELKNSGTVEAKKHELVSVLFSDFKGFTHFAEDMTPEMLVKSISYYFSEFDNIIEKNGLEKIKTIGDAYMCAGGLSFPDKEHAKKLTLAAQEMIDFVTTAKNDVSRDYANFEIRIGINSGPVVAGVVGSKKFAYDIWGDTVNVASRMESMSEVGRINISEMTYNLIKSDFECEYRGEFEIKNHGKLNLYFVNSVLTQVFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFE3</accession>
    <name>A0A5C6ZFE3_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">30S ribosomal protein S10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">rpsJ</name>
        <name evidence="6" type="ORF">ESY86_14825</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in the binding of tRNA to the ribosomes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00508">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001848">
        <property type="entry name" value="Ribosomal_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018268">
        <property type="entry name" value="Ribosomal_S10_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027486">
        <property type="entry name" value="Ribosomal_S10_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036838">
        <property type="entry name" value="Ribosomal_S10_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11700">
        <property type="entry name" value="PTHR11700"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00338">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00971">
        <property type="entry name" value="RIBOSOMALS10"/>
    </dbReference>
    <dbReference type="SMART" id="SM01403">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54999">
        <property type="entry name" value="SSF54999"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01049">
        <property type="entry name" value="rpsJ_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00361">
        <property type="entry name" value="RIBOSOMAL_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_S10" evidence="5">
        <location>
            <begin position="6"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD87940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="101" mass="11379" checksum="DCA14A29DC24D22F" modified="2019-11-13" version="1">MSQKIRIKLKSYDHSLVDKSAEKIVKTVKSTGAVVTGPIPLPTHKRIFTVLRSPHVNKKSREQFQLSSYKRLLDIYSSSSKTIDALMKLELPSGVEVEIKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFF4</accession>
    <name>A0A5C6ZFF4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RagB/SusD family nutrient uptake outer membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_13435</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SusD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033985">
        <property type="entry name" value="SusD-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012944">
        <property type="entry name" value="SusD_RagB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14322">
        <property type="entry name" value="SusD-like_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07980">
        <property type="entry name" value="SusD_RagB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="SusD-like_3" evidence="6">
        <location>
            <begin position="20"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="SusD_RagB" evidence="5">
        <location>
            <begin position="324"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD88305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="442" mass="48826" checksum="13E8A467047410C1" modified="2019-11-13" version="1">MKNILYIVITCMAVYSCDVLDVEPQNSISAAEAFKTKEDIDKGILGAYASFQSLSYYGRTYSIFADLAADNLSHPLDATALEYAEVDNNNLLPENGSSSNMWAIMYDGINVANNVIAKVPSIADMSAEEQDEALAELYFIRAMNHFDLTRYYGAIPLKLTPTVGVTGLDAPRAPLDAVYAQLISDLTFAAENMPSSGTKTRGSKYAAKALLARVYLYQKNYAQAASMASEVIDEGGYSLLPNYADIFAEENTAESIFEISFSQLERNRIAEYNFPRSLNGRREVQPSADLLEAYEAGDTRFDTSIAFAEILAYAIKYDDLSLGADNFIVLRLADLYLIRAEALAKGTAPEVTQIKADLNTIRARAGLSNITSNNVGQLISAIEKERRVEFAFEGHRWFDLVRTDRAVDVLFNVTSVNQTLFPIPFDEIQTNNDPAMVQNPGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFF7</accession>
    <name>A0A5C6ZFF7_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Isocitrate dehydrogenase [NADP]</fullName>
            <ecNumber evidence="1">1.1.1.42</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Oxalosuccinate decarboxylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_11015</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-threo-isocitrate + NADP(+) = 2-oxoglutarate + CO2 + NADPH</text>
            <dbReference type="Rhea" id="RHEA:19629"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.42"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="4">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="4">Binds 1 Mg(2+) or Mn(2+) ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the monomeric-type IDH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.42" evidence="1"/>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004450">
        <property type="term" value="F:isocitrate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006097">
        <property type="term" value="P:glyoxylate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004436">
        <property type="entry name" value="Isocitrate_DH_NADP_mono"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36999">
        <property type="entry name" value="PTHR36999"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03971">
        <property type="entry name" value="IDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009407">
        <property type="entry name" value="IDH_monmr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00178">
        <property type="entry name" value="monomer_idh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0329">Glyoxylate bypass</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 5" id="KW-0521">NADP</keyword>
    <keyword evidence="1 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="133"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="83"/>
            <end position="88"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="548"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="585"/>
            <end position="586"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="590"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="601"/>
            <end position="603"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="650"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="site" description="Critical for catalysis" evidence="2">
        <location>
            <position position="256"/>
        </location>
    </feature>
    <feature type="site" description="Critical for catalysis" evidence="2">
        <location>
            <position position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR009407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR009407-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR009407-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR009407-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR009407-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD88764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="740" mass="81738" checksum="B92C9EA80EB69BB5" modified="2019-11-13" version="1">MAKTPSIIYTKTDEAPALATHSLLPIIQAFTKSSNINVESRDISLAARILANFPDFLTDEQKVHDALAELGDLAKRKEANIIKLPNISASIPQLKDALLELQSKGYKLPNYPDEPKNEAEKSIKSRYDKIKGSAVNPVLREGNSDRRAPKAVKNFAKRHPHSMGKWAADSKTHVATMSHGDFAHNEISITLPEATSVNIVHTDASGNTTVLKENLNLLKGEIIDATVMSKKALIEFLKAEVKDAKDKNVLFSLHLKATMMKVSDPIIFGHAVRVYFQDLFKKYDTLFDEISFDPNNGFANLIDKLDQLPSEKRKQLEKDIEASFENAPSVAMVNSDKGITNLHVPSDVIVDASMPAMIRTSGKMWNAQGKLQDTKAVIPDSSYAGVFSATIDFCKKHGAFDPTTMGTVPNVGLMAQKAEEYGSHDKTFEIASDGKVEVMDANGEILTKHDVEQGDIWRMCQVKDAPIEDWITLAVSRARASKIPAVFWLDDERAHDVELIKKLNIYLPKLDTSGLEIKILSPVEATNYTLERVKAGLDTISVSGNVLRDYLTDLFPILELGTSAKMLSIVPLMNGGGLFETGAGGSAPKHVQQFLEENHLRWDSLGEFLALAMSLEHFGNVNDNEKAIILSETLDAATEKLLLDGKSPSRVVNEIDNRGSHFYLAMFWAEALANQTKNEALKHEFAQVFRDLQAHEAKISEELIVVQGKSLNIGGYYEPTEDLVSQAMRPSDTFNKIING</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFG0</accession>
    <name>A0A5C6ZFG0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Iron-sulfur cluster repair di-iron protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ric</name>
        <name evidence="5" type="ORF">ESY86_11250</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012312">
        <property type="entry name" value="Hemerythrin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019903">
        <property type="entry name" value="RIC_family"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36438">
        <property type="entry name" value="PTHR36438"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01814">
        <property type="entry name" value="Hemerythrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04405">
        <property type="entry name" value="ScdA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03652">
        <property type="entry name" value="FeS_repair_RIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hemerythrin" evidence="4">
        <location>
            <begin position="87"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD88808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="243" mass="27944" checksum="7F4C03D866F3C824" modified="2019-11-13" version="1">METLQRDTQKQIGQFVAEDFRTAAVFSKHKIDFCCRGNRTLAEVCEKNDIDCDQLLGELDASMNSKSDQSIDYKSWPLDLLAEYIEKKHHRYVEEKTPVLRQFLDKLCKVHGERHPELFKINELFTASAGELAAHMKKEELMLFPFIKNMVKAKLANTEVKAPGFGTVKNPIATMMQDHDNEGVRFREIAALSDNYTPPADGCNTYQVTFAMLEEFEKDLQLHIHLENNILFPEAVKLEQQFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFG2</accession>
    <name>A0A5C6ZFG2_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5 7">50S ribosomal protein L15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplO</name>
        <name evidence="10" type="ORF">ESY86_14925</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Binds to the 23S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uL15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01341">
        <property type="entry name" value="Ribosomal_L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036227">
        <property type="entry name" value="L18e/L15P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030878">
        <property type="entry name" value="Ribosomal_L15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005749">
        <property type="entry name" value="Ribosomal_L15_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001196">
        <property type="entry name" value="Ribosomal_L15_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021131">
        <property type="entry name" value="Ribosomal_L18e/L15P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12934">
        <property type="entry name" value="PTHR12934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00828">
        <property type="entry name" value="Ribosomal_L27A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52080">
        <property type="entry name" value="SSF52080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01071">
        <property type="entry name" value="rplO_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00475">
        <property type="entry name" value="RIBOSOMAL_L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L18e/L15P" evidence="9">
        <location>
            <begin position="28"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD87960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="150" mass="15970" checksum="470BEF9AFD23A445" modified="2019-11-13" version="1">MDLSNLKPAEGSNKNQGKRIGRGQGSGKGGTATRGHNGAKSRSGYSKKVGFEGGQMPLQRRVPKFGFTNRNRVVYQGVNLDKLQQLADDKKISDVVDFQTLVELGLAGKNEMVKILGRGELKSTLKVTAHKFTASAKAAIEAAGGEVVTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFM1</accession>
    <name>A0A5C6ZFM1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">M1 family metallopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_11340</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="2">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034015">
        <property type="entry name" value="M1_LTA4H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45726">
        <property type="entry name" value="PTHR45726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="SSF63737"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022696093" evidence="3">
        <location>
            <begin position="19"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M1_N" evidence="5">
        <location>
            <begin position="50"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M1" evidence="4">
        <location>
            <begin position="271"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="339"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="413"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="338"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="342"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="361"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR634015-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR634015-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD88824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="548" mass="63028" checksum="4264900F858E83A4" modified="2019-11-13" version="1">MKHFIIGILLLAFDLSIAAQGLMADKQAQFTHQDSLRGSITPERAWWDLTYYHLEVQINPDDKSIKGKNTVQYTVLNPKKTLQIDLQSPLTISKIVQDGKELQFKSDGNAHFVTLEHPQPKGSTQNLEVYYEGHPKVAVRAPWDGGFSWKKDDNGNDFIATSCQGLGASVWWPCKDHMYDEVDSMLISVTVPKDLMDVSNGRLRSKEQHKDGTSTYNWFVGNPINNYGVNVNVGDYVHFAEDYAGENGNLTMDYYVLPANLEKAKVQFKDATRMMEAFEYWFGPYPFYEDGFKLVEVPYLGMEHQSSVTYGNQYMNGYLGRDLSGTGWGLKFDFIIIHESGHEWFANNITNKDIADMWIHEGFTAYSENLFLDYFYGKEASSAYVIGTRRIIENDKPIIGPYGVNQEGSGDMYYKGANILHTLRQLINDDQKWRQILRGLNEVFYHQTVTTKQIEDYISQESGMDLSAFFNQYLRDIRIPTLEYSVENNQLKYRWANVVADFKMPVQVSIADEAIWLYPTSAWKNMKLESNIKTIDLDADFYVFSKRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFN4</accession>
    <name>A0A5C6ZFN4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aldehyde dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_14295</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3 7">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006081">
        <property type="term" value="P:cellular aldehyde metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012394">
        <property type="entry name" value="Aldehyde_DH_NAD(P)"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43570">
        <property type="entry name" value="PTHR43570"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036492">
        <property type="entry name" value="ALDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="8">
        <location>
            <begin position="24"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="active site" evidence="4 5">
        <location>
            <position position="216"/>
        </location>
    </feature>
    <feature type="active site" evidence="4 6">
        <location>
            <position position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR036492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR036492-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD88055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="470" mass="52918" checksum="46E03646610A6F63" modified="2019-11-13" version="1">MTDFSDNPFIELFKSQEQHQFLIGNATYKQRITKLKALRKAVEHTYKQEIRDALYKDFKKPSLEVDLTEIYPIVDEIKFVSKHLKSWLKKQKVETPMALLGSSSWIKNEPKGVCLIISPWNFPINLTFGPLVSAIAAGNTVIIKPSEMTPNASAIMAKIVNRVFDEHEVALVEGEVEVSTQLLKLPFNHIFFTGSPQVGKIVMEAASKNLSSVTLELGGKSPVIVDDSSNIDKAVQRICFGKFVNAGQTCIAPDYVFVNASVKDAFVTSFKKQIKEWYGEDISKSESFSRIVNQKHFKRLQSYIDDAQANQTEIFRGGASDEKDNFIAPTLVLNPGDDSKLMQNEIFGPILPVKTYVNIKEAVHYINQKEKPLALYIFSKNKQNTNYIINNTRAGGTCINHNLLQYLNHNLPFGGSNNSGIGKSHGYFGFLEFINQRAVLKQHTLGAVDLLLPPYTNFKQKLVDLTIKWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFU3</accession>
    <name>A0A5C6ZFU3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidoglycan DD-metalloendopeptidase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12135</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M23" evidence="1">
        <location>
            <begin position="94"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="227" mass="25722" checksum="2DFBB8A39C2A4864" modified="2019-11-13" version="1">MKKTLEQLIKALPDCSVLEPSIPKNQFVAIDLSRDSDVLNHIDVSSSQILAAYIDDYIAEKKARYAYGGYMEVRNIYQRSTYFKNNMPSNERYIHLGLDIWAPSETSIFTPLDATLHSFKNNINFGDYGPTIILRHEIEGTGFYTLYGHLSLESLAHLEIGQTFKQGEQIGALGDASVNGDYPPHLHFQIMADIQDYFGDYPGVSSKQDFEFYKQNCLDPSFLLGLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGG0</accession>
    <name>A0A5C6ZGG0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_09035</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="146" mass="17576" checksum="97FDCBBFED76764D" modified="2019-11-13" version="1">MVFFRIASGQKDYVRNYDPNGILQAEGWMLNNEKVDFWTYYHNNGSIAKKGNFNHGKKHGYWYFYSENKMLLKEGRFKNDKASDWWIFYSEKGTQKVQFENGMKEGYALVYRDSRLRKAERYSSNQKTGEWTSYFSFKKDNPNLKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGJ8</accession>
    <name>A0A5C6ZGJ8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycogen synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">glgA</name>
        <name evidence="3" type="ORF">ESY86_11435</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009250">
        <property type="term" value="P:glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011875">
        <property type="entry name" value="M1P_synthase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02149">
        <property type="entry name" value="glgA_Coryne"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="15"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="197"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="401" mass="44848" checksum="6D04A365727A4409" modified="2019-11-13" version="1">MKVLFYTREFPPYVYGGAGVHVEYLAEELAKLMPMEVRSFGDQDAHAENLKVKGYDFESEDFKTADAKLKAVLQTLRTCVNMNIDPVDADVVHCHTWYAHFAGIVSKLCYGTPLVITTHSLEPLRPWKREQLGRGYDASSWVEKTAIEMADAVIAVSKETKEDVLKHFDVDEAKVKVIYNGINLVEYNVTDKTDTLVAHGIDPTKPYVLFVGRITRQKGIIHLVNAIKHIHGETQIVLCAGAPDTPEIAQEMKDSVEAVQKTRDNVIWIDKMLPKPEVIQLYSHADVFCCPSIYEPFGIINLEAMACETAVVASAVGGIKEVVVNDETGILVSVEQQTEAPFEPLHPEKFSQDLADSINYLVNNPTIRKQMGLAGRQRVESTFDWAAIAKQVQELYQTLKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGN4</accession>
    <name>A0A5C6ZGN4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PKD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_12830</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001070">
        <property type="term" value="F:starch binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022409">
        <property type="entry name" value="PKD/Chitinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000601">
        <property type="entry name" value="PKD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035986">
        <property type="entry name" value="PKD_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032187">
        <property type="entry name" value="SusF/SusE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16411">
        <property type="entry name" value="SusF_SusE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00089">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49299">
        <property type="entry name" value="SSF49299"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50093">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023032496" evidence="1">
        <location>
            <begin position="21"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="PKD" evidence="2">
        <location>
            <begin position="54"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="domain" description="PKD" evidence="2">
        <location>
            <begin position="138"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="304" mass="33127" checksum="764114BFD11DB0F3" modified="2019-11-13" version="1">MNTILKYLSLAVIFMCFACSNDDSDIIEYQQPVVDFSNEAIEGNSQLLSFTNLSENATSFQWDFGDGSDNSYEKHPSHLYNPGGAYMVTLKGFNGDKATVISKEIMVAGNPVANFSYTTDAIVLYQLNFENLSQNADSFQWDFGDGEGTSTVENPSYTYTSAGTYSVTLLVQGAGGTNSTSIDVIITEPQPSYDALYIVGDASPSGWNIGSPEAFTQSNTDAFIFTYQAVLTAGEFKISTFQGDWCDGDWLNPPNNGDDLSENSFITTSGCEGPDNKWMLTSANEGTYLITVDLSDQTIVFELQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGP4</accession>
    <name>A0A5C6ZGP4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_09615</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="2"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="103" mass="11873" checksum="D21BA9068B21DCA0" modified="2019-11-13" version="1">MVVELRKKQGISQTDLASQLGIHKNVFGRYERNEVLPSIEIARKIADILDVSLDYLTGKADVQMDKNTRERILEVSKFEEEDKQHIFSVIDAFIAKRKIQSIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGT1</accession>
    <name>A0A5C6ZGT1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08085</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Abhydrolase_3" evidence="1">
        <location>
            <begin position="87"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="280" mass="31948" checksum="CD024772185A1074" modified="2019-11-13" version="1">MIKKNQVLDRKTEKPIVYDTFFKEDQTKKPIVIFCHGYKGFKDWGSWDLVAKAFMASDLFFVKFNFSHNGGTIEEPIDFPDLEAFAENNYTKELNDLESMLDVLVSENFEFKNEINPHDITVIGHSRGGGIAVLKASEDARITKLISWASVSDFGKRGTMTSDLEQWKKDGVKYVINGRTKQQMPHNYQFYEDYKANEARLSIPSAAKKIEIPYLIVHATDDPSVSFAEAEDLHRFNDKSELSPVQNSNHVFGSSHPWKEEVLPKALKDVVKKSVQFITA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGX1</accession>
    <name>A0A5C6ZGX1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sterol desaturase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_09100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008610">
        <property type="term" value="P:lipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006694">
        <property type="entry name" value="Fatty_acid_hydroxylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04116">
        <property type="entry name" value="FA_hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid hydroxylase" evidence="2">
        <location>
            <begin position="122"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="295" mass="35210" checksum="DD49AB257A0E12A9" modified="2019-11-13" version="1">MEKYLDIILNSYSGYWRYLKNELIDIYHWDNYFYGLIGLSLLVWGLEILFPWRKNQPVFRKDFWLDTFYMFFNFFLLNLIVLIALSNTAAEIFNDILGFSGLHVSNFELFDIDVLPRWLGLFIFFLISDFVQWNTHRLLHRVPMLWNFHKVHHSVKEMGFAAHLRYHWMEPVVYNSLLYIPIAIIGGFDAQDVAIVHFFAIAIGHLNHANLGWDYGKLKYIFNNPKMHIWHHAKELPEHTKYGVNYGITLSTWDYIFRTDHIPSDGRDIELGFDEDENFPKDFLRQSIYPLKTKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGX2</accession>
    <name>A0A5C6ZGX2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SUF system Fe-S cluster assembly protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08325</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002744">
        <property type="entry name" value="MIP18-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014291">
        <property type="entry name" value="SUF_FeS_clus_asmbl-assoc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01883">
        <property type="entry name" value="FeS_assembly_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="SSF117916"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02945">
        <property type="entry name" value="SUF_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FeS_assembly_P" evidence="1">
        <location>
            <begin position="12"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="107" mass="12162" checksum="C12359E61DB3DCFB" modified="2019-11-13" version="1">METKIDTNALGEKIVRILKTIYDPEIPVDIYELGLIYDVFVNEDYDVKILMTLTSPNCPVAESLPAEVEEKVRSLNDVKTAEVEITFDPPWTQELMSEEAKLELGML</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGY6</accession>
    <name>A0A5C6ZGY6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF819 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_13010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008537">
        <property type="entry name" value="DUF819"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34289">
        <property type="entry name" value="PTHR34289"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05684">
        <property type="entry name" value="DUF819"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="183"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="245"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="293"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="322"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="347"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="376"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="406"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="436" mass="46686" checksum="40500352110853E5" modified="2019-11-13" version="1">MDNSPIFTDDTIIFGLLMLSLGFVFFTESIKTGFWPKFYKIVPGLFMAYMIPAILTTSGLIAPEWETVSESGEIIKNKTSLYYMASRYLLPAALVLMTLSIDLKGVFNLGWKALVMFFTGTIGIVIGGPIAILLISSVSPDTVGGVGPDAVWRGLSTLAGSWIGGGANQTAMLEIYGYNQAKYGGMVFVDIVVANIWMAIILIGIGKRDRINKWLKADTASIEALKKRMSEFSENVKRNPTLTDLMIIAAIAFGTVSIAHLCANFLAPFFKKVVSGITSQTTRNIFTFLDSEFFWMISIATIIAIVLSFTKAKNMEGAGASKYGSVFIYILVATIGMKMDLKLIFDNVGLIAIGVVWMSIHALSLIGMAKLIKAPYFFLAVGSQANVGGAASAPIVAAAFHPSLATVGVLLAVFGYAVGTVAAIGCTILMQLAAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHC3</accession>
    <name>A0A5C6ZHC3_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3 4">50S ribosomal protein L19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rplS</name>
        <name evidence="5" type="ORF">ESY86_11020</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 4">This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the bacterial ribosomal protein bL19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00402">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038657">
        <property type="entry name" value="L19_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001857">
        <property type="entry name" value="Ribosomal_L19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15680">
        <property type="entry name" value="PTHR15680"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01245">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002191">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00061">
        <property type="entry name" value="RIBOSOMALL19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01024">
        <property type="entry name" value="rplS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD88765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="116" mass="13409" checksum="B528D023B1F8F4E9" modified="2019-11-13" version="1">MSSLVDFVQDEFVTRKEFPAFGAGDTITVYYEIREGEKVRTQFFRGVVLQRKGTGTTETFTIRKMSGTIGVERIFPINLPALQKIEVNKKGKVRRARIFYFRGLTGKKARIKEVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHR1</accession>
    <name>A0A5C6ZHR1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Exosortase/archaeosortase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11985</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="567" mass="65078" checksum="9C1F4384A3015C61" modified="2019-11-13" version="1">MFANYWRRGVKQKIISVLVIAALIIALFVLRDDYQPVLLFVRKYIFVILLSLIVLFFGLRAFRNSASTGRRLGILALLITFFALIYLVGWHLKFYDYMKTYNVFNDLNKVEINELPLTQNERIQPLRNIYSMANESVGETKDVSLPHLVRVDNENKWTMAIQPSEKYSLQQIRDDIEEVFSVSSTSPFPRFSAENRIPVIFSIGESLKFSRNTYNAVVQRFNPWMLINYEPGDTFYMKNDSGEWVEVVSLIKWKGFFFPYPSFGGVMVIESGEHDFNDYLERIAIGKGKYISPDELKNYPYLTKQNTLAQKVSRLQAESLKFLGGFSDPLPWNMETAVKIPNLASDQNQQPFVTDFDFAGSASDAYSGLYHWFGLEPIGAERTSLSFSVFVPADGTDKLYYYDHAAKKQGYAGVSAMPLKVIESRKEFDWSVNKPVEFRPYIKDIAGRRRLFFLGTISAIRESNAGQFDGAATPDLALIDSEYRDVVWIDVKHPSTWDQAIYDQLNEAWRASEGIGYFYENAETDEDLMIQNAVDSIMAVPSTNRNTEEIDRLQKRLDSLKSAEPKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHS6</accession>
    <name>A0A5C6ZHS6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">VWA domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_12090</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023112117" evidence="1">
        <location>
            <begin position="20"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="273"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="478" mass="52834" checksum="95A3A2417A4F9D80" modified="2019-11-13" version="1">MKQLFKMAFVLLIGMHVNAQDIRIKGTVSSSNDGAPLPGANVTIKGTTKGTQTDFDGKYSIETAIGKTLIFSYVGFEIQEIKVANSTKLDVVLKEDSAALEEVVVTAYGSRASKSSSSSIAIRGASSISGKVSGVSVNNQPSYGQLTAGEINDIEKWDEWLKALRKSEYKYIQKNWEFSLEDRVVVDVRDAEGHAINNVPVSLYNNAREKIMSSRTDMTGKAVLFKDFSHKCKDEYFTVQIQQDGKVTGQKITSSYDEVRFVLDQKQQSNDIDIMFTIDATGSMGDEIDYLKAELQNIISRLDQSIAKKRVALTFYRDHGDDYVVKDFDFNEDVKSVQDILANQHAGGGGDYEEAVEQGLATSMSKSWNENAKSKLLFLLLDAPPHLTQENVTIIKEQIKLAQAKGIKIIPIVASGANKNVEFLMRFFSVSTNGTYVFLTDDSGIGNAHIDPTTDKFKVEKLNDLIVRLIEKYAGVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHU6</accession>
    <name>A0A5C6ZHU6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Toxin-antitoxin system YwqK family antitoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011652">
        <property type="entry name" value="MORN_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07661">
        <property type="entry name" value="MORN_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022873972" evidence="1">
        <location>
            <begin position="23"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="236" mass="27109" checksum="8931AD39B9C0AD5C" modified="2019-11-13" version="1">MIKQKKYCLTLIVIFLTLITNAQSLVNQYDEAGKRDGLWSKNFDNTTQPRYEGEFDHGKEIGLFKFYTLKQGKSVLSATKQFNKNNDNADVTFFSSKGKKISEGQMDGKLYVGKWLFYHNKVDAVMSEDFYNDEGQLEGKKTIFYPIGKIAETSHYKAGKLNGVTEVYAETGVLLKQYTYQNDELHGAAKYYDANGKIAAEGVYQHDRKHGIWTYYLDGELEKTIDHTRRSQNPKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI15</accession>
    <name>A0A5C6ZI15_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Acyl-CoA desaturase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_10765</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016717">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03505">
        <property type="entry name" value="Delta9-FADS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015876">
        <property type="entry name" value="Acyl-CoA_DS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11351">
        <property type="entry name" value="PTHR11351"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="157"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="FA_desaturase" evidence="8">
        <location>
            <begin position="5"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD88966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="246" mass="29222" checksum="7DB19758B8866774" modified="2019-11-13" version="1">MIIILFVLVLWYGGLFFQSFFLHRYAAHQVFTMSKSMERLTFVLTWIFQGASYLSAYGYGIMHRMHHAYTDTEQDPHSPSHDANVFAMMWKTKNVYQDINQQRIVVDQRFTKNVPQWKSFDSFASSRLSRLLWIGLYILFFAFFATAWWQWLLLPVTLFMAPIHGVIINWFGHIYGYVNFKMKNTSKNLFPFDFLMMGEGYHNNHHKYASRANFGVKWHEIDMTYLIIKVLDALGFIQLKPIPVRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZID1</accession>
    <name>A0A5C6ZID1_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase</fullName>
            <ecNumber evidence="7">6.3.2.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Meso-A2pm-adding enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Meso-diaminopimelate-adding enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">UDP-MurNAc-L-Ala-D-Glu:meso-diaminopimelate ligase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">UDP-MurNAc-tripeptide synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">UDP-N-acetylmuramyl-tripeptide synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">murE</name>
        <name evidence="12" type="ORF">ESY86_09370</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + meso-2,6-diaminoheptanedioate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate</text>
            <dbReference type="Rhea" id="RHEA:23676"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
            <dbReference type="ChEBI" id="CHEBI:83905"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="7 8">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="7">Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the MurCDEF family. MurE subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.13" evidence="7"/>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008765">
        <property type="term" value="F:UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diaminopimelate ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00208">
        <property type="entry name" value="MurE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000713">
        <property type="entry name" value="Mur_ligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035911">
        <property type="entry name" value="MurE/MurF_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005761">
        <property type="entry name" value="UDP-N-AcMur-Glu-dNH2Pim_ligase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01225">
        <property type="entry name" value="Mur_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63418">
        <property type="entry name" value="SSF63418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01085">
        <property type="entry name" value="murE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7 8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 7 8" id="KW-0132">Cell division</keyword>
    <keyword evidence="3 7 8" id="KW-0133">Cell shape</keyword>
    <keyword evidence="6 7 8" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 7 8" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase" evidence="9">
        <location>
            <begin position="24"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_M" evidence="11">
        <location>
            <begin position="110"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="10">
        <location>
            <begin position="326"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-MurNAc-L-Ala-D-Glu binding" evidence="7">
        <location>
            <begin position="154"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Meso-diaminopimelate binding" evidence="7">
        <location>
            <begin position="403"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Meso-diaminopimelate recognition motif" evidence="7">
        <location>
            <begin position="403"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="112"/>
            <end position="118"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="379"/>
        </location>
        <ligand>
            <name>meso-2,6-diaminoheptanedioate</name>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="456"/>
        </location>
        <ligand>
            <name>meso-2,6-diaminoheptanedioate</name>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="460"/>
        </location>
        <ligand>
            <name>meso-2,6-diaminoheptanedioate</name>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-carboxylysine" evidence="7">
        <location>
            <position position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TXD89244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="487" mass="54330" checksum="920217F093F0A702" modified="2019-11-13" version="1">MAQLKDILYKVTINAVTGSTSIDVNNIDFDSRNIKDNDVFVAIKGTTVDGHDFVEVAIKNGAKAVVCETLPLELADGITYIEVESTSKALAFMAANFYGNPSENLKLIGVTGTNGKTTVTTLLYDLFKKAGFKVGLLSTVRVMVDNKEYKATHTTPDSLTINKYLKLMNDEGVEFCFMEVSSHGIHQNRTFGLQFEGGVFTNLSHDHLDYHSSFAEYRDVKKSFFDHLPKQAFALVNIDDKNGLVMLQNTQAKTYTYALKTYADYKAQVLENEFSGLLLKLNDNELWSKLIGSFNAYNITAIYGVADLLGLEKVEILRLISELESVSGRFQYVISEGRITAIVDYAHTPDALKNVLETINSIRTKNEELITVVGCGGNRDKTKRPTMGQIASALSTKVIFTSDNPRNEVPETIIEAIEKGVEPQNFKKIISITDRKQAIKTACQMANSKDIILIAGKGHETYQEIKGERFDFDDYKLVTEFLKQMEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIE8</accession>
    <name>A0A5C6ZIE8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06955</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="237"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="339" mass="38950" checksum="46C95B7E1F90D997" modified="2019-11-13" version="1">MKICKVNSLPLKEVIESLAVYFETEAQEKCGEYIFNIPSGFGEGQIRGLNFDNGLGVIIYSCRFHNDVRIDFTVDDVHPVKYIYSVQGTIEHSFANEDEMHLIEQYQCAIIASKSKSGHILFFKKDTNIEVVSLEIDRKTFLVHTECEVEDLAAELQELYQDTTAKKEFYHKGFFGLDFKNLLDNMSKYSDKMLIRKYYLESVALQIFVNQLLQFEDDLLKDSESSILRINELKRIEDISQYIKDNLTGDLSINSISKKTGLNPNKLQLGFKYIHGSTVNEFVTGAKLDKALQLLQDPNLNVSDVVHQVGFDSKSYFSKIFKKKFELTPSVYQQICLTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZII6</accession>
    <name>A0A5C6ZII6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">T9SS type A sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_07070</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023034520" evidence="1">
        <location>
            <begin position="21"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="Por_Secre_tail" evidence="2">
        <location>
            <begin position="288"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="355" mass="40276" checksum="C3EFD9E0AEC88AF3" modified="2019-11-13" version="1">MTKLFTQIFLLILFSLQINAQTVFTDSFGGELPNSIEIVGNNMFVSTFSTQKLYKLNLDNIDDIETVTNFNGPLWKIRFDSTNNDYYCIVLDNPNSLSVVDLDSNIPITSNILENVTNSNGITINNGVVYVSDNNNLYGYVINSGNYSLVYQESDGNIRNPTVYNNEIYFQVYDTDSNDIYKIDISSQNPTKTLVSTDNNFGILQASLVVNNYIYLGFESPNKIVRINLSELNLPIEPTTIFENLGGGVIGLTNKEDQIYYTTGQQIIYEFSDQVLNNQEFVLSQEKLYPNPAENYITYQSNVNYDLYEIYSITGSLVGNGKFNNSINIEKLVGGLYFIIFKNEQKTKTFKFIKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIJ2</accession>
    <name>A0A5C6ZIJ2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lmo0937 family membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043727">
        <property type="entry name" value="DUF5670"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18919">
        <property type="entry name" value="DUF5670"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="55" mass="5922" checksum="FD8CBF45C7C4B6D6" modified="2019-11-13" version="1">MRSILWLVAAVCIIVWLLGLLGVIPGLGSSNLIYILLVIAVIIILYNIISGRSAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIQ9</accession>
    <name>A0A5C6ZIQ9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">Phosphoribosylamine--glycine ligase</fullName>
            <ecNumber evidence="2 7">6.3.4.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">GARS</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Glycinamide ribonucleotide synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Phosphoribosylglycinamide synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">purD</name>
        <name evidence="10" type="ORF">ESY86_07845</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>5-phospho-beta-D-ribosylamine + ATP + glycine = ADP + H(+) + N(1)-(5-phospho-beta-D-ribosyl)glycinamide + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17453"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:58681"/>
            <dbReference type="ChEBI" id="CHEBI:143788"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 7">Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the GARS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.13" evidence="2 7"/>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004637">
        <property type="term" value="F:phosphoribosylamine-glycine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009113">
        <property type="term" value="P:purine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00138">
        <property type="entry name" value="GARS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020561">
        <property type="entry name" value="PRibGlycinamid_synth_ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000115">
        <property type="entry name" value="PRibGlycinamide_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020560">
        <property type="entry name" value="PRibGlycinamide_synth_C-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037123">
        <property type="entry name" value="PRibGlycinamide_synth_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020562">
        <property type="entry name" value="PRibGlycinamide_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43472">
        <property type="entry name" value="PTHR43472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01071">
        <property type="entry name" value="GARS_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02843">
        <property type="entry name" value="GARS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02844">
        <property type="entry name" value="GARS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01210">
        <property type="entry name" value="GARS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00877">
        <property type="entry name" value="purD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="9">
        <location>
            <begin position="111"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD89683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="423" mass="46390" checksum="82A5B83FC323B651" modified="2019-11-13" version="1">MTILILGSGGREHTFAWKIVQSTSCEKLYVAPGNSGTAQIATNVDLKVTDFEAIKKLVIEKQINMVVVGPEDPLVQGIHDFFLNDEQLKNVAVIGPQKAAAQLEGSKEFAKEFLIKHKIPTAAYQSFDASTVANGYEFLETLKPPYVLKADGLAGGKGVLILQDLEEAKVELKNMLVDAKFGAASSKVVIEEFLDGIELSCFVLTDGEHYKILPTAKDYKRIGEGDTGLNTGGMGAISPVPFATESFLNKIEERIVKPTVLGLQKDNLPYKGFIFIGIIKVGDEPKVIEYNVRMGDPETEVVLPRLKNDLVEIFEAIANERLHEIELQIDERTAATVMLVSGGYPEAYEKDKEITGLDELSGSIAFHAGANSKEGKIVTAGGRVMAITSFGDSYQAAIKKSYQNIEKLHFDKMYYRKDIGFDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ46</accession>
    <name>A0A5C6ZJ46_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_05435</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="179" mass="20557" checksum="B011030C3DF9F57F" modified="2019-11-13" version="1">MSIDSENTKSRLFLVCPNGFMEVPVREKFGDNSYFFTAMAVFFEWDEASQHNLMEFVQRRNISEIYFVGNLDNPLYVKFIDNPVIPLRVPWERQLALGYTDLKTEIEGLAGAKMKNKMLLADYLERQMSFLKALPVLGSYLLKEDIKINAVVYDPADHSFQSATKVSFQGKLLSGICYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ88</accession>
    <name>A0A5C6ZJ88_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Methylated-DNA--protein-cysteine methyltransferase</fullName>
            <ecNumber evidence="7">2.1.1.63</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">6-O-methylguanine-DNA methyltransferase</fullName>
            <shortName evidence="7">MGMT</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">O-6-methylguanine-DNA-alkyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_07535</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>a 4-O-methyl-thymidine in DNA + L-cysteinyl-[protein] = a thymidine in DNA + S-methyl-L-cysteinyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:53428"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:10132"/>
            <dbReference type="Rhea" id="RHEA-COMP:13555"/>
            <dbReference type="Rhea" id="RHEA-COMP:13556"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:82612"/>
            <dbReference type="ChEBI" id="CHEBI:137386"/>
            <dbReference type="ChEBI" id="CHEBI:137387"/>
            <dbReference type="EC" id="2.1.1.63"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 7">
            <text>a 6-O-methyl-2'-deoxyguanosine in DNA + L-cysteinyl-[protein] = a 2'-deoxyguanosine in DNA + S-methyl-L-cysteinyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:24000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:10132"/>
            <dbReference type="Rhea" id="RHEA-COMP:11367"/>
            <dbReference type="Rhea" id="RHEA-COMP:11368"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:82612"/>
            <dbReference type="ChEBI" id="CHEBI:85445"/>
            <dbReference type="ChEBI" id="CHEBI:85448"/>
            <dbReference type="EC" id="2.1.1.63"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="7">This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the MGMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.63" evidence="7"/>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89629.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003908">
        <property type="term" value="F:methylated-DNA-[protein]-cysteine S-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006307">
        <property type="term" value="P:DNA dealkylation involved in DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06445">
        <property type="entry name" value="ATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00772">
        <property type="entry name" value="OGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001497">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014048">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036217">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNAb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023546">
        <property type="entry name" value="MGMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036631">
        <property type="entry name" value="MGMT_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01035">
        <property type="entry name" value="DNA_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46767">
        <property type="entry name" value="SSF46767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53155">
        <property type="entry name" value="SSF53155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00589">
        <property type="entry name" value="ogt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00374">
        <property type="entry name" value="MGMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4 7 9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA_binding_1" evidence="8">
        <location>
            <begin position="70"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; methyl group acceptor" evidence="7">
        <location>
            <position position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD89629.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="157" mass="17587" checksum="228893A202748C73" modified="2019-11-13" version="1">MESCIINTPLGFTKILGDTEGISEVTVLNSVEKETDVIPDELEDAVIQLREYFEGVRQNFDLKLNPQGTDFQKSVWQLLEAIPFGKTISYLELSKQLGDIKAIRAVANANGKNPLWIVVPCHRVIGSDGSLTGYAGGLHRKKWLLEHEDPYKQQSLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJC3</accession>
    <name>A0A5C6ZJC3_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Malate dehydrogenase</fullName>
            <ecNumber evidence="2">1.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">mdh</name>
        <name evidence="8" type="ORF">ESY86_04635</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the reversible oxidation of malate to oxaloacetate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>(S)-malate + NAD(+) = H(+) + NADH + oxaloacetate</text>
            <dbReference type="Rhea" id="RHEA:21432"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.37"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the LDH/MDH superfamily. MDH type 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.37" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030060">
        <property type="term" value="F:L-malate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01339">
        <property type="entry name" value="LDH-like_MDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00487">
        <property type="entry name" value="Malate_dehydrog_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001557">
        <property type="entry name" value="L-lactate/malate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022383">
        <property type="entry name" value="Lactate/malate_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001236">
        <property type="entry name" value="Lactate/malate_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015955">
        <property type="entry name" value="Lactate_DH/Glyco_Ohase_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011275">
        <property type="entry name" value="Malate_DH_type3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02866">
        <property type="entry name" value="Ldh_1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00056">
        <property type="entry name" value="Ldh_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000102">
        <property type="entry name" value="Lac_mal_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00086">
        <property type="entry name" value="LLDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56327">
        <property type="entry name" value="SSF56327"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Ldh_1_N" evidence="6">
        <location>
            <begin position="1"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="Ldh_1_C" evidence="7">
        <location>
            <begin position="147"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2 3">
        <location>
            <position position="175"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="7"/>
            <end position="12"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2 4">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="118"/>
            <end position="120"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2 4">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2 4">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD90046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="308" mass="32585" checksum="D7991275D824C2B2" modified="2019-11-13" version="1">MKVTVVGAGAVGASCAEYIAIKNFASEVVLLDIKEGFAEGKAMDLMQTASLNGFDTKITGVTNDYSKTADSDVCVITSGIPRKPGMTREELIGINAGIVKTVSSSLIENSPNTIIIVVSNPMDTMTYLVHKTTSLPKNRIIGMGGALDSARFKYRLAEALEAPISDIDGMVIGGHSDTGMVPLTAHATRNSIKVSEFISEARLEQVKEDTKVGGATLTKLLGTSAWYAPGAAVSSMVQAIACDQKKMFPCSVLLDGEFGLKDLCIGVPVILGRNGIEKIVSIKLSDAEQKHMEQSAEGVKKTNALLEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJH1</accession>
    <name>A0A5C6ZJH1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_09570</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="110" mass="12709" checksum="C269C697E8724D85" modified="2019-11-13" version="1">MALLKKIKASTLMETLVATVLIVIIFMLSSMILNTIFSSSIKNNTQSISTYLNELHYLQKHKKIELPYYEDFENWRISIVKFSEDNKKSLEFEAVNSETEKTITIIVDEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJR9</accession>
    <name>A0A5C6ZJR9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Histidinol dehydrogenase</fullName>
            <shortName evidence="4">HDH</shortName>
            <ecNumber evidence="4">1.1.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 11" type="primary">hisD</name>
        <name evidence="11" type="ORF">ESY86_10445</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>H2O + L-histidinol + 2 NAD(+) = 3 H(+) + L-histidine + 2 NADH</text>
            <dbReference type="Rhea" id="RHEA:20641"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="ChEBI" id="CHEBI:57699"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4 9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="4 9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 9/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 5 10">Belongs to the histidinol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.23" evidence="4"/>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00014"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004399">
        <property type="term" value="F:histidinol dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06572">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01024">
        <property type="entry name" value="HisD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001692">
        <property type="entry name" value="Histidinol_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022695">
        <property type="entry name" value="Histidinol_DH_monofunct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012131">
        <property type="entry name" value="Hstdl_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21256">
        <property type="entry name" value="PTHR21256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00815">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000099">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00083">
        <property type="entry name" value="HOLDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00069">
        <property type="entry name" value="hisD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00611">
        <property type="entry name" value="HISOL_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="1 4 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 7" id="KW-0520">NAD</keyword>
    <keyword evidence="3 4 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 9" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton acceptor" evidence="4 6">
        <location>
            <position position="322"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4 6">
        <location>
            <position position="323"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 7">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 7">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 7">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 8">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 8 9">
        <location>
            <position position="255"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 8 9">
        <location>
            <position position="258"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 8">
        <location>
            <position position="323"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 8 9">
        <location>
            <position position="356"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 8">
        <location>
            <position position="410"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 8 9">
        <location>
            <position position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR000099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000099-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000099-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000099-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000099-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD88909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="430" mass="46647" checksum="A35A4FCE9D6D88C6" modified="2019-11-13" version="1">MNKVFNPDKSTWSALLKRPTQSLENIEQTVNDIFSDVQRNGEAAISKYTEMFDAVKVETLLVSEAEIIEASTKVSEALKQAIQVAKQNIEVFHTAQKTERISLETTKGVQCWQEKRPIQKVGLYIPGGTAPLFSTVLMLAIPANIVGSKEIVLCSPPNKQGKIANEILYAAQLCGVTKIAKVGGIQAIAGLTFGTENIPQVYKIFGPGNQYVTVAKQLATKHGVAIDMPAGPSELLVVADDSANASFVASDLLSQAEHGADSQVILVSTSKQLIEDVSEAVAQQLQQLPRKDMAQKAIDNSKLIFVASHEMALELINAYAPEHFIICTENEAFYTENIINAGSVFIGNYTPESAGDYASGTNHTLPTNGFSRAYSGVNLDSFTKSITFQKITKEGIKTIGHSIELMAEAEGLRAHKNAVSLRLKDLEKEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJS5</accession>
    <name>A0A5C6ZJS5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">YifB family Mg chelatase-like AAA ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_06295</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032508">
        <property type="term" value="P:DNA duplex unwinding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045006">
        <property type="entry name" value="CHLI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004482">
        <property type="entry name" value="Mg_chelat-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025158">
        <property type="entry name" value="Mg_chelat-rel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000523">
        <property type="entry name" value="Mg_chelatse_chII-like_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32039">
        <property type="entry name" value="PTHR32039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32039:SF7">
        <property type="entry name" value="PTHR32039:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01078">
        <property type="entry name" value="Mg_chelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13335">
        <property type="entry name" value="Mg_chelatase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00368">
        <property type="entry name" value="TIGR00368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="2">
        <location>
            <begin position="213"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="512" mass="56550" checksum="007DB95A2F1E7687" modified="2019-11-13" version="1">MLKKVFGSAVFGVEATTITVEVNVDSGIGYHLVGLPDNAIKESSFRIAAALQNNGYKIPGKKIIINMSPADLRKEGSAYDLTLAIGILVATDQIKAEELEKYLIMGELALDGNLQPIRGALPIAVKAKEEGFKGFILPKQNAKEAAIVDGLEVYGVENISEVIGFFDRNEPMEQTIINTREEFYKNLDFPEHDFSDVKGQESIKRCMEIAAAGGHNIILIGPPGAGKTMLAKRLPSILPPMTLHEALETTKIHSVVGRVKAHTGLMAQRPFRSPHHTISNVALVGGGSYPQPGEISLSHNGVLFLDELPEFKREVLEVMRQPLEDREVTISRAKFTVTYPSSFMLVASMNPSPSGYFNDPGSPVTSSPAEMQRYLSKISGPLLDRIDIHIEVTPVPFEKLADERKGESSVDIRKRVTAARELQTLRFEDSETVHYNAQMNTKQIRKHCKLDDASMQLLKTAMERLNLSARAYDRILKVSRTIADLEAANDINGSHISEAIQYRSMDREGWLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJX1</accession>
    <name>A0A5C6ZJX1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">PAS domain S-box protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_10665</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="4">
        <location>
            <begin position="125"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="4">
        <location>
            <begin position="247"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="4">
        <location>
            <begin position="368"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="5">
        <location>
            <begin position="445"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="4">
        <location>
            <begin position="664"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="5">
        <location>
            <begin position="1228"/>
            <end position="1280"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="4">
        <location>
            <begin position="1277"/>
            <end position="1320"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="5">
        <location>
            <begin position="1348"/>
            <end position="1402"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="4">
        <location>
            <begin position="1399"/>
            <end position="1469"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="5">
        <location>
            <begin position="1472"/>
            <end position="1524"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="1542"/>
            <end position="1756"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="1264"/>
            <end position="1291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD88949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1759" mass="201147" checksum="2DE780D651111374" modified="2019-11-13" version="1">MTPSQLNSLYNDQSKDPIWMIDLDFQLIYANKRWLDLVKEVTGKELKLYESAFAGGFGEGYIEKWKTYYSRALKGEYFEIEEHYSHPETNEIHYGQITLEPLRGDDGKIFAIACQSRDITSIVKHRSEANQLIDASLDIFCTINEQGNFVFVSAAASTHWGYLPKELIGKAYVDFILEEDLPKTSDIAASILRGQDVKSFVNRYKKKNGGIAYNLWSVTWDNTSKLMYCTIRDAKELIDQEEKIKQSEQRFKALVQEGSDLISILNPDGKYIYTSPTSISVLGITPEELKGRNAFEFIHPDDAERVLASLQKISTENKLIIGPFRYKNKKDEWRWLETVLTNMLDNPAVNGIVANSRDITHGIEEKHQLKLLESVITNTNDAVLITEAEPFDEPGPKIIYVNEAFTKMTGYEAEEVIGKTPRMLQGPKSNGEELAKLGRSLKKWEPYEITTINYKKSGEEFWINFTVTPVADEKGCYTHWIAIERDVTEQKNKEREKNLISTISDIFNQSAANDLTKCLTEVCEYITQFGHFDFAEIWLPAIDAKTINRVSKYVEGKAGSVFYDTAKNKDSFALGEGIPGHIWLNEMTEIWEDIDEEWHFFKRKVAAEKAGIKAMMGVPLKHKNEVVGVLLLGTAKTKSAIGLHLELFEKLESTIGAELSRKKTEIELAQIFNFTPDMICVSGFDGYIKRINPAGLELLGYSLEEMRSRPIKSFIHEEDKLKTQEKWKHLYNGGSLRNFENRYITKRGDSVWLSWTASPAPEHGIVYSVAKNITEEKKLRELDRQVRSITKIGSWELDLLNQSLFWSEEVHLLHETDPKSFVPDLKKAINFYRADFREMVRSSIKKCIANKEPYDFEAVLVTANKKELWVRTNGTAEFVDGVCTRIYGSFQDIDERKQIEIRLLSLADNLPAVVYQYIFYPDGTDALKYVTKGSQQVWGFAAEEVIENNQLVWERMAVAGAFETVNKSIADAMETKTKWTARWQYAMPNGETRTHLGYGSPIFLADGSVVFNSVILDVTNEAKNEALLEQITKIARIGSWEMDLVNQDGDNMYWSPMLFEIVEVDDSYNPTLTGGIEFHIGESKERIQKALDLLINEGVEFDEEILLRTAKGNERWSRAIGKSEIVDNKCIRIYGSYQDIHERKVAALELEKSLKALKDYKFSLDQSAIIAFTNEKGVITSVNANFCKISKYNEEEIIGKTHRLINSKHHAKAFFKELWKTIASGNVWRGEIKNKAKDGSYYWVDTTIVPFLDKKNKPTQYLAIRFDITERKNAEQEKNSLQETLENSLNEIYTFNAETLKFSYVNKGALLNMGYSEQEIKALTPVDIKPDFTAASFEQLVIPLVSNEKNKIIFFTNHKRKDGSLYPVVVHLQLITQENNKRFLAIVLDITERKKAEEENRFKANLLSMIGQAAIATNLDGVVNYWNNAAETIYGWKAEEALGKNIMDLTPFKATEVQAKQIMEELKKGERWSGEFEVRKKDGTNFPAQVTNSPIYDEHHKLSGIIGISSDITQEVKNKELLKQYTHELERSNEELEQFAFVTSHDLQEPLRMISSFMTLLQRKYGDQLDDKAHQYIHFATDGAKQMKQIILDLLEYSRANASTEGKEDVDLNEVLSEFKQLRRRLISEKSASITSSDLPSLTTYSATITQIFHCLLDNALKYSKDGTAPIIEIKASEHEKEWEFSIKDNGIGIDPQFYDKIFVIFQRLHNKDEYSGTGIGLSIVKRHIEFLGGRIWLDSKPGEGTVFYFTISKIKQHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK12</accession>
    <name>A0A5C6ZK12_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_04530</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027791">
        <property type="entry name" value="Galactosyl_T_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02709">
        <property type="entry name" value="Glyco_transf_7C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="8"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_transf_7C" evidence="3">
        <location>
            <begin position="183"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD90638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="274" mass="31178" checksum="15A40AB2A6C5B98B" modified="2019-11-13" version="1">MSTYLKASVIISTYNKPECLAMVLYSYGLQTEQQFEIIVADDGSDTRTEKVIADFSEAHHLKISHVWQEDDGFQKTKILNKAILAASANYLVFTDGDCIARKDFVETHLKLRRENCALSGGYFKMNSNVSEAITKEVISNQSCFDKDWLLKQGQAKSFKLNKLTKSTTKAKLLNSLTPTKATFDGMNVSCWKADILRVNGFDERMAYGAEDREVGERMMNNGVKFLQIRYSAICVHLHHERPYKNEVVLEKNKGIRANTKTKKLTYTQFGIKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK77</accession>
    <name>A0A5C6ZK77_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_05530</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="65" mass="7867" checksum="5DE5866852B3B631" modified="2019-11-13" version="1">MIYIKFQDLSMEKQEELLQVSREHVTHLFGDSIKKYVEETGANYENLIDEEMIKNLYNYNFVFNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK84</accession>
    <name>A0A5C6ZK84_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">AAA family ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_05585</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="179" mass="21232" checksum="C31213D54C9F56D0" modified="2019-11-13" version="1">MKILLFGASGCGTTTLGREIQKSTDFVHLDVDDYYWKKSETPFQEKIPLKERNKNLKKDFETFQNVIVSGSMVSWGKEWETAFDLVVFIRLENDERMKRLGERERKRYGKKLYRDKNVQQSSKAFLEWANQYENPNFNGRSLKTHNDWMKSIDCKVLKMDGETKLEHKVEIIIKEIKIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKC0</accession>
    <name>A0A5C6ZKC0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_08625</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039426">
        <property type="entry name" value="BtuB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30069">
        <property type="entry name" value="PTHR30069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0675">Receptor</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022959895" evidence="1">
        <location>
            <begin position="23"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="2">
        <location>
            <begin position="117"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="847" mass="93020" checksum="4087EE5BAA7260BE" modified="2019-11-13" version="1">MKKVSQCLTILVLTMFCSFAFAQSTVSGTIIGSDMNQPLPGVNVIEKGTSNGSATNFDGQFIINTKSATGELVLSFVGYTSKTIAFSGDMDLGKIMMDPSEVGLQEVQIIASVAVDRKTPVAVSTIRASEIELKLGSQEFPEILKSTPGVYVTKTGGGFGDGEIRLRGFNSENVAVMINGVPVNDMENGRVYWSNWAGLGDVTSSMQVQRGLGASKVAVPSIGGTINIISKTTDVEEGGNFYTTLGNDGFKKFGVTYSTGLMDNGLAVTVSGSKTDGDGYVDGTPFNAISYFLNVSKEINDKHKIALTAFGAKQTHGQRQNPYLVETFRESESGRKYNSDWGYKDGQFTSVEDNFYHKPQISLNHYWNISQASSLSTAAYVSVGSGGGGGFSGVNKFRFDDDEYRIGNLGTVDFDKIVSENETAGVEGSESILRASRNDHIWYGVLSTFKTDLTDDLVLLTGLDLRGYEGFHFTEVTDLLGGQYFSDASDVNNPNNQAQVGDKILYDNDGKVGWLGGFVQAEYDIQENFNAFVSVSASNTSYQRVDRFLYLDSDPLQESDVYNFFAYGAKGGANYRLDDRNNVFFNLGYFERAPFFNSIFANRNNTDVNGDAPNQRITSFEVGYGHRAEKLSANINLYHTTWKDRTEFASFQAQDGTRNFANILGVNALHMGVELDFNYRVSSTFSVTGMASIGDWRWQNNVEDVIIFDEENNAVGDPINLFIEDLHVGNAAQTTFGLGTIYKLTPKTTFTIDYLYNGDIYADYDPSNRTTKRPDAFKLPDFGLFDSAIRHGFKFGSLDAELTGRINNIFDTEFIADARDGAESDVFTTRVFYGFGRTFSLGAKLNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKC9</accession>
    <name>A0A5C6ZKC9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminotransferase</fullName>
            <ecNumber evidence="1">2.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_02125</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.-" evidence="1"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="2">
        <location>
            <begin position="32"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="381" mass="42805" checksum="71A7E70CE8F77CD0" modified="2019-11-13" version="1">MIAVANRLAHVEEYYFSKKLREVAALKAKGKPIINLGIGSPDLAPPERVLNGLVEAFEEPSAHKYQSYQGIPELREAIAKFYRTQFKTYLNADNEILPLMGSKEGIFHVSLAFLNPGDEVLIPNPGYPTYASVTNLVGATPVFYDLTETNDWHPDLLALEKRGLKKVKLMWVNYPHMPTGATASNKLFEDLIGFAKRNDILLVNDNPYSFVLNPKPRSILKYKGAKDVCLELNSLSKTFNMAGWRVGMLLGHETYLKAVLKVKSNMDSGMFLGIQRGAIEALDCSELWYGSLNSVYQERREVAWKIADVLKCTYDKNATGLFIWAKLPEHIDAEDYVDTILKERSIFIAPGTIFGSNGKGYIRISLCAELEEMEEALARLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKF4</accession>
    <name>A0A5C6ZKF4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">CPXCG motif-containing cysteine-rich protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_05640</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025990">
        <property type="entry name" value="Cys_rich_CPXCG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14255">
        <property type="entry name" value="Cys_rich_CPXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="60" mass="6951" checksum="CE2ECDB01F8C9E23" modified="2019-11-13" version="1">MEEQFFQCPYCWETISMLVDVSQSHQSYIEDCEICCNPIQLIISSQNNEIVGFDALSIEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKH0</accession>
    <name>A0A5C6ZKH0_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">3-hydroxyacyl-CoA dehydrogenase</fullName>
            <ecNumber evidence="2">1.1.1.35</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ESY86_03785</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>a (3S)-3-hydroxyacyl-CoA + NAD(+) = a 3-oxoacyl-CoA + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:22432"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57318"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:90726"/>
            <dbReference type="EC" id="1.1.1.35"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; fatty acid beta-oxidation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.35" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00659"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003857">
        <property type="term" value="F:3-hydroxyacyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006635">
        <property type="term" value="P:fatty acid beta-oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006176">
        <property type="entry name" value="3-OHacyl-CoA_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006108">
        <property type="entry name" value="3HC_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00725">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02737">
        <property type="entry name" value="3HCDH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="4" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3HCDH_N" evidence="9">
        <location>
            <begin position="8"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="3HCDH" evidence="8">
        <location>
            <begin position="209"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD90496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="802" mass="89441" checksum="31416D3876E62557" modified="2019-11-13" version="1">MSKRRIKKIAIIGSGIMGSGIACHFANIGVDVLLLDIVPRELNDKEKAKGLTLEDKEVRNRLVNDSLTESLKSKPSPIYDKAFASRIKTGNMEDDIAKVKDVDWIMEVVVERLDIKQQVFEKLEKYRTPGTLITSNTSGIPIHFMSEGRSEDFQKHFCGTHFFNPARYLELFEIIPGPKTDQEVLDFLNEYGEKFLGKTSVIAKDTPAFIGNRIGIFSIMSLFHAVKDMDMTVEEVDKLTGPVIGRPKSATFRTVDVVGLDTLVHVANGIYENCPKDERHELFKLPGFIDTMMEKKWLGSKTGQGFYKKIRKDDGSSEILTLDLETLDYRDSKRAKFGTLEQTKTIDKVEDRFEVLVNGKDKAGDFYRKTFAALFAYVSHRIPEITDELYKIDDAMRAGFGWEHGPFQIWDAIGVEKGLKMIKDEGHEVDSWVAGMLESGSDSFYSVKDGNSYFYDIPSKKQEKIPGQDSFIILDNIRKTKEVFKNSGVVIEDLGDGILNIEFQSKMNTIGGDVLAGVNKGIELAEKDFAGLVVGNQAKNFSVGANIGMIFMMAAEQEYDELNAAIKYFQDTMMRMRYSSIPTVAAPQGMSLGGGCELSMHADKVVAAAETYMGLVEFGVGVIPGGGGSKEMTVRAQDTFRTGDVELNTLQEYFLTIGMAKVSTSAYEAFDLGLLQKGKDIVVVNKHRQLAVAKQQAKLMADIGYTQPVKRTDIKVLGKQALGMFLVGTDSMEDSNYISEHDKKIANKLAYVMAGGDLSEPTLVSEQYLLDLEREAFLSLCTERKTLERIQHMLKTGKPLRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKH3</accession>
    <name>A0A5C6ZKH3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribbon-helix-helix domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_01890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013321">
        <property type="entry name" value="Arc_rbn_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038733">
        <property type="entry name" value="Predicted_DNA_bind_prot_RHH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12651">
        <property type="entry name" value="RHH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RHH_3" evidence="1">
        <location>
            <begin position="4"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="81" mass="9384" checksum="0196BE167B49335D" modified="2019-11-13" version="1">MATFTSSLPDDLLEKLANEAKNLHIPKNKLIEKALTMYLQELKKARYAKSFRRASEDKDVMAMAEEGMADYFEMLQKHDTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKR4</accession>
    <name>A0A5C6ZKR4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP-dependent Clp protease adaptor ClpS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_04300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003769">
        <property type="entry name" value="ClpS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014719">
        <property type="entry name" value="Ribosomal_L7/12_C/ClpS-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02617">
        <property type="entry name" value="ClpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54736">
        <property type="entry name" value="SSF54736"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ClpS" evidence="1">
        <location>
            <begin position="21"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="91" mass="10317" checksum="0686EE960B0B3A39" modified="2019-11-13" version="1">MSTKEKIQEESQVDTLEQHLNEIVLFNDDVNSFDHVIDTLMYVCNHTPEQAEQCSILVHYKGKCTVKTGTYDELEPKCSKLLEAGLSAEIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKW4</accession>
    <name>A0A5C6ZKW4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">M28 family peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05825</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="PTHR12147"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M28" evidence="1">
        <location>
            <begin position="95"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="296" mass="33018" checksum="F43646AA26EA1F50" modified="2019-11-13" version="1">MKHLLIYFFFSITSFAQSTYDATSIASIKHCIYTLANDSLYGRAAGSAEELKTLAYIEHSITKFTDLKMQRQAFDIKTATYETLIANNGYYFLDNNSDTTLLLSAHYDHIGLGGDLSTAFTAGQIHNGADDNASGVALTISLFQAIIERKLTDFNYVVAFYSGHELGLHGSSAFAEVLQHQTKMDHTISAVINIDMVGRFDPELKSIRIYSNKAADSYFENFTEIDPNLLVLKGSEKKLELLDTKTFHAQNLPCLSMTTGVHLDYHKPSDDAQYINYEGIVTIRDYILQLIVGLSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKZ2</accession>
    <name>A0A5C6ZKZ2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GNAT family N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05995</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="141" mass="16642" checksum="0ED19F085426FFCB" modified="2019-11-13" version="1">MDFQFKILDASEIFQIIPMIQKLSNAKNSEAILRERFSEMVNQNYECAVIYHQKQLVGMSGLWFSTRHYVGKTVELDHVYIETDYRNQGLGKQFLAWIYAHVKAKGCNSAELNTYVQNYPSHKLYYNEGFEILGYHFLKHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL35</accession>
    <name>A0A5C6ZL35_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">Pyruvate kinase</fullName>
            <ecNumber evidence="4 12">2.7.1.40</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">pyk</name>
        <name evidence="15" type="ORF">ESY86_08165</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + pyruvate = ADP + H(+) + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:18157"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.40"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the pyruvate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.40" evidence="4 12"/>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00188"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030955">
        <property type="term" value="F:potassium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004743">
        <property type="term" value="F:pyruvate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.33.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1380.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001697">
        <property type="entry name" value="Pyr_Knase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018209">
        <property type="entry name" value="Pyrv_Knase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015793">
        <property type="entry name" value="Pyrv_Knase_brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015795">
        <property type="entry name" value="Pyrv_Knase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036918">
        <property type="entry name" value="Pyrv_Knase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015806">
        <property type="entry name" value="Pyrv_Knase_insert_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11817">
        <property type="entry name" value="PTHR11817"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00224">
        <property type="entry name" value="PK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02887">
        <property type="entry name" value="PK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01050">
        <property type="entry name" value="PYRUVTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="SSF50800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52935">
        <property type="entry name" value="SSF52935"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01064">
        <property type="entry name" value="pyruv_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00110">
        <property type="entry name" value="PYRUVATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10 12" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="7 12 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="9 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11 15" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PK" evidence="13">
        <location>
            <begin position="5"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="domain" description="PK_C" evidence="14">
        <location>
            <begin position="361"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TXD89357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="480" mass="53363" checksum="E01EB7056E0B6360" modified="2019-11-13" version="1">MLRKKKTKIVATLGPATSTREVLKGMLEEGVNVFRVNFSHADYKDVKERVEMIRSLNEEFGYNASILGDLQGPKLRVGVMKGEVIVNAGDEVVFATGERFEGTKERVYMTYDKFPQDAKPGERVLLDDGKLIFEVISTDGISEVKTRVIQGGPLRSKKGVNLPNTNISQPALTEKDIEDAIFACSIQVDWMALSFVRHAEDLMQLEQLIKQHSKHKIPIIAKIEKPEAVENIDKIVAYCDGLMVARGDLGVEIPAEEVPLIQKQLVLRAKRARIPVIIATQMMETMITSLTPTRAEVNDVANSVMDGADAVMLSGETSVGNYPVQVIRQMANIIRSVEDSDLIKVPQSPPHIRTKRYITKAICYHAAHMANEISAKAISTLTNSGYTAFQISAWRPKAHILVFTSNRRILTQLSLLWGVEAFYYDKFVSTDETIEDVIAIACKKGYLEVGDMQISLAAMPIQEKGMVNTLRVSEITSCSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL37</accession>
    <name>A0A5C6ZL37_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_04070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="160" mass="18865" checksum="7445FFC8A3AF745B" modified="2019-11-13" version="1">MELSHHKKQLIEDVGVLLEERANLSPLASRIYALLILSCYEGMSFEDVVTSMQASKSSVSSNLNVLLQLHYVDYYTKPGDRKRYFRTSQFYIKNTMEQQVHLIDKELKIVQKVNQFNKEHNPEKFKNEKSLGLLFQEHLEDQRTKINQKIEEINQFEKQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL60</accession>
    <name>A0A5C6ZL60_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">YqcI/YcgG family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_06890</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014988">
        <property type="entry name" value="Uncharacterised_YqcI/YcgG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40045">
        <property type="entry name" value="PTHR40045"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08892">
        <property type="entry name" value="YqcI_YcgG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="219" mass="25874" checksum="876B8D50EF7B55F4" modified="2019-11-13" version="1">MKIENEQDIEKEFREFIIKQKHPCIMANTVFKLKKYHLKIYEDITSNEIITPILKDISEYLEHYDFNSNEFESLMVCFKTNNFDCEKAFETALWTFLQKLHNADDVGWDNRVSNDSGSPHFSFSLKGTAFYIVGMHPNSSRIARRAPYCTIVFNMHWQFEKLREMGTYQTVKKRIRSRDKKLQGSINPVLRDFGSDSEARQYSGRTIEADWSCPFHLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL62</accession>
    <name>A0A5C6ZL62_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MMPL family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_02060</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004869">
        <property type="entry name" value="MMPL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000731">
        <property type="entry name" value="SSD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03176">
        <property type="entry name" value="MMPL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50156">
        <property type="entry name" value="SSD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="225"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="251"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="277"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="318"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="354"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="409"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="613"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="639"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="667"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="708"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="738"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="domain" description="SSD" evidence="8">
        <location>
            <begin position="251"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="SSD" evidence="8">
        <location>
            <begin position="639"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="780"/>
            <end position="804"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD90769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="804" mass="91687" checksum="AE101002472166DF" modified="2019-11-13" version="1">MTTGFWKVVARLILRNKISILIFIILATLLFSSQWKHMRFTFSEANLLPDDHEVNLIYNDFLKIFGEEGNLIVLGVKDSTLFSVEKLNAWNQLSEDFKKFNAVESVVSIKDLQKLVKNDEEQKFDLEPFIKDSLSSMAQINRLKKQLFEQYPFYDNFLFNKKTETVRTAIYIKKDIVNTEARKDFIINELEPLIQDFETATEMDVRVSGMPYIRTLNSQYIVDEIGLFIGGALLVTSFIFFLFFRSFRATFISLIVVCIGVMWTFGILGLLGYEITVLTALIPPLIIVIGIPNCIFLINKYQREVKLHGNKVRSLQRVITKVGNATLMTNITTASGFATFILTESTLLKEFGVVASLSILSIFLLCLLIIPIIYTFLPYPKERHLEHLNKRWIGGFVNWIEHMVKNQKIAIYGTSLLLIILSIIGIYQIKVSGSLIEDMPQDAEFFQDIRFFEEEFNGIMPLEIMIDTKRKKGVMKLNTLERMERLEELINDIPELSRPISVVSLVKYSKQAYYNGNPKYYQLPTRQENSFILSYAKNSSGNADMLKNFVDSTGQYARITTFMKDIGTDNMQRIEEDLLTKINKEFPKDRYDVILTGKALVFQKGTNYLVKNLVISLSLAIFLIALFMAYMFRSFRMIIVSLIPNLLPLLITAGLMGYLGVPIKPSTILVFSIAFGISVDDTIHFLAKYRQELQANHWKIRKSVFGALRETGVSMFYTSIVLFFGFSVFTISSFGGTVALGALVSATLLFAMLSNLLLLPSLLLGLERSIANKDTLREPSINIIPGENDEEDDEEDDSAKKIKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL88</accession>
    <name>A0A5C6ZL88_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Histidine--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Histidyl-tRNA synthetase</fullName>
            <shortName evidence="8">HisRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">hisS</name>
        <name evidence="10" type="ORF">ESY86_00080</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-histidine + tRNA(His) = AMP + diphosphate + H(+) + L-histidyl-tRNA(His)</text>
            <dbReference type="Rhea" id="RHEA:17313"/>
            <dbReference type="Rhea" id="RHEA-COMP:9665"/>
            <dbReference type="Rhea" id="RHEA-COMP:9689"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78527"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.21"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3 8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.21" evidence="8"/>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004821">
        <property type="term" value="F:histidine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006427">
        <property type="term" value="P:histidyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00773">
        <property type="entry name" value="HisRS-like_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00859">
        <property type="entry name" value="HisRS_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00127">
        <property type="entry name" value="His_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015807">
        <property type="entry name" value="His-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041715">
        <property type="entry name" value="HisRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004516">
        <property type="entry name" value="HisRS/HisZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033656">
        <property type="entry name" value="HisRS_anticodon"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13393">
        <property type="entry name" value="tRNA-synt_His"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001549">
        <property type="entry name" value="His-tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00442">
        <property type="entry name" value="hisS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="9">
        <location>
            <begin position="1"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD91034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="456" mass="51078" checksum="D185776424DBE4DC" modified="2019-11-13" version="1">MAQKPSIPKGTRDFNPTEVAKRNYIIHTIKAHFERFGFQPIETPSFENSETLMGKYGEEGDRLIFKILNSGDFLNKADAKAYDSKDSNKITASISEKALRYDLTVPFARYVVQHQNEIEFPFKRYQIQPVWRADRPQKGRFREFFQCDADVVGSSSLWQEVEFVQLYDTVFSALKLEGCSIKINNRKILSGIAEVIGAQDKLIDFTVALDKLDKIGEEKVKAEMLEKGIPQSGIDKLQPLFSIEGDFGSQIDQLKSILNTSEEGKKGIEELEFINNGIATLGLKTATLQLDVTLARGLNYYTGAIFEVSAPEGVAMGSIGGGGRYDDLTGIFGLKDVSGVGISFGLDRIALVLEELNLFPETITNTVKVLFINFGEREAMASMKAIKQLRERGVSAELFPDNKKTIKQFNYANKRNIPFVVLLGESELESETYTLKNMISGEQDQLSFEEMLQQLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLA5</accession>
    <name>A0A5C6ZLA5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="23"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="95" mass="11093" checksum="1DCFD4FDFDC24054" modified="2019-11-13" version="1">MNSKKTILLPKYKKIFEQIGENIKLARKRRKLTTEQVSERAGIHRATLYRIEKGDPAVSIGLYFNVFRVLNLQDDFLKLAVDDEFGRKLQDLDLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLF5</accession>
    <name>A0A5C6ZLF5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_03685</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="187" mass="21610" checksum="8144954AFF2624F8" modified="2019-11-13" version="1">MEDEKFIFCLEAVPDIESDTTTDVVKILENIALKQGVASIYKACDSIEGLEESLSNLLYDDHNFKDYEIIYLVMPGESNNILLNDYYYSIEEIAELFEGKMNGKVIHFANKKVLDLTDEESQYFLDVTGARAISGYGSELQEISSANTIDRVFFSMYQENDDLKEVVESMFQKHYNLCKLLDFRLYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLH6</accession>
    <name>A0A5C6ZLH6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_04785</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="109" mass="12720" checksum="E64DE265735BAEDD" modified="2019-11-13" version="1">MAIIVFAVGWTYFITRMPQEKFNETIWVNDIQERNKMIKDLLESDYLIGQKSSHIKAVFGKPEAVNHEEGVLTYTLIGHTALDWKIISLKLFMKDSIVKKFTYDTRIAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLN5</accession>
    <name>A0A5C6ZLN5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Iron ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_02970</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="73"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="154"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="252"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="301"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="339"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="378"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="421"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="479"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="531"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="69"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="342"/>
            <end position="547"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD90969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="554" mass="62123" checksum="85C73548BA92A168" modified="2019-11-13" version="1">MRQGGNKNKAFSLKTRLKRLKRDSNRWSVFTLAIVLFLALPIVFIGVELFSGPGETWGHIVEYLLPDYIWNSLYLVFFCSILVLVLGVSSAWFVSRFDFLFRKQMEWLLILPLAIPSYIVGYAYAGIFDYGGSMDLIFRQLNLDFVRIDIMNRAGLAFVLSISLFPYVYVSARAFFLNQANNLLEASKMLGVGEAKTFFKLMLPLARPAIVAGLVLVLMEVLNDYGAAKYYGVNTFTTGIFRSWFSLEEPQTAVYLSALLILIIFALILFEKWQVRKVKFTSAKSNSTQIQRKEPKGAIKWGIFSVVLLPILLGFILPVAQLIYWAILTASTVFDFRFIVLSLQSFGIAITSAIITVFFALLLIYFSKWSALRFIKNVARVGVLGYAIPGAVIAIGIMIPTLALDKWLIKMLGNFGIDSGLIINGTLIALFYAYAVRFLAVAYNPIDSTALKVDNSIPDSSKVLGVGNLKTFFKIEFPLIKTGVFSAVILVFIDVMKELPLTLILKPYHVDTLAVKAFEYASDEMVMEASIPSLFIIFTAMIPVIFLNKLLIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLQ7</accession>
    <name>A0A5C6ZLQ7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">HTTM domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_06615</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008488">
        <property type="term" value="F:gamma-glutamyl carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017187">
        <property type="term" value="P:peptidyl-glutamic acid carboxylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011020">
        <property type="entry name" value="HTTM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007782">
        <property type="entry name" value="VKG_COase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12639">
        <property type="entry name" value="PTHR12639"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05090">
        <property type="entry name" value="VKG_Carbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00752">
        <property type="entry name" value="HTTM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="58"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="88"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="111"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="150"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="204"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="231"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="304"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="HTTM" evidence="6">
        <location>
            <begin position="10"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD89870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="455" mass="54347" checksum="217693529EB6FA9F" modified="2019-11-13" version="1">MKFNLKTYFSKTTNAAPLAVFRIGFGLMMLVSIIRFWWHGWIETIYIQPTFHFKYYGFDWVSSLGAYNYVLFFICGLSALFIALGFKYRWAMLAFFLSFTYIELIDKTTYLNHYYFITVLSFLMLFLPANAKFSIDNLLRKKSYDTIPRWCIDSIKLLLAMVYFYAGLAKINSDWLFRAMPLKIWLPSKYDLPFIGNSLMQQEWFHFAMSWSGMFYDLTIPFLLLYKRTRLFAFALVVFFHIFTRVLFPIGMFPYIMIVATLVFFDASVHEKIIAFIKRLLKPFRSHFSEPKLVSNYSIANQKWILPVLTVFLAFQMLFPFRYAFYKDELFWTEEGFRLSWRVMLMEKMGLTTFKIVDAKTGDYFYVDNSDFLTNFQVKQMSFQPDFILEYAHYLGDHFKEQGHKNIQVFVESYVALNGRLSQQYVNPEVDLYQEKESFKRKNWILPFKDEIKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLW5</accession>
    <name>A0A5C6ZLW5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_00305</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005182">
        <property type="entry name" value="DUF304"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03703">
        <property type="entry name" value="bPH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="bPH_2" evidence="2">
        <location>
            <begin position="89"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD91076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="171" mass="19021" checksum="B260CE00988C9CCF" modified="2019-11-13" version="1">MFTNTQIDTNALPQIDQVELHPIDKAYLKIIVINKLLVYGVIVLALILAKLFLVDVLIQSYFWLLAAAVGLLCLSNFMLALLAFKKRMYALRDKDVIYAHGLLIHRLTTVPISRIQHIETSRSWLSRQFGLATLNIYTAGESGSDLSIKGLSEAEATRINDFLSTTVNGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM05</accession>
    <name>A0A5C6ZM05_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF3822 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_03355</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024213">
        <property type="entry name" value="DUF3822"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12864">
        <property type="entry name" value="DUF3822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="290" mass="33653" checksum="32A03B6ECEB6D997" modified="2019-11-13" version="1">MPPKPFGKTVTSVILLINPKPLKTLSKKALSIQISLNGLSFCILDTSEKTVHYLKSVTFEKKKAPHELLEKLKAAIETQSLLQQPFDAVYCVYQNELSCLVPEPLFDEENLAEYLKFNAKILKTDYLAYDAIPCIKSMNVFIPLVNINNYIFETFGKFTYKHASTVLIESLIQRQHQTIGTALYLNVNSSSFEMLAIKNKQLQFYNSFNYHSKEDFIYYLLFTVEQLKLDPEAVKLYLFGHIDEQNELFQIAYRYIRHVELFEPEQQFKLDRSITTTNLSAYFSLLNSFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM96</accession>
    <name>A0A5C6ZM96_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA polymerase sigma factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_03890</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000838">
        <property type="entry name" value="RNA_pol_sigma70_ECF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01063">
        <property type="entry name" value="SIGMA70_ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="3">
        <location>
            <begin position="24"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="4">
        <location>
            <begin position="124"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="196" mass="22889" checksum="82993388E681E1A6" modified="2019-11-13" version="1">MTINKDQILINQIVKGDTSAFTVLVDNYKDLVFTLALRMLKNREEAEEVAQDTFIKAYKSLANFKGDSKFSTWIYRVAYNTCLDRIKKNKKHLNDVPIDEFTEHELKTIDNALQQLMTAEKNETIKKCIAQLPSDDAFLLTLYYFDDLSLEEISKVVDLTPNNIKVKLFRFRKKLASILKVQLEPEIIATYERERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMA1</accession>
    <name>A0A5C6ZMA1_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 10">Adenylosuccinate synthetase</fullName>
            <shortName evidence="8">AMPSase</shortName>
            <shortName evidence="8">AdSS</shortName>
            <ecNumber evidence="8 10">6.3.4.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">IMP--aspartate ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">purA</name>
        <name evidence="11" type="ORF">ESY86_03435</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 10">
            <text>GTP + IMP + L-aspartate = GDP + 2 H(+) + N(6)-(1,2-dicarboxyethyl)-AMP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15753"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57567"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="6.3.4.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8 10">Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1 8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8 10">Belongs to the adenylosuccinate synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.4" evidence="8 10"/>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00075">
        <property type="reaction ID" value="UER00335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004019">
        <property type="term" value="F:adenylosuccinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044208">
        <property type="term" value="P:'de novo' AMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03108">
        <property type="entry name" value="AdSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00011">
        <property type="entry name" value="Adenylosucc_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018220">
        <property type="entry name" value="Adenylosuccin_syn_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033128">
        <property type="entry name" value="Adenylosuccin_syn_Lys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042109">
        <property type="entry name" value="Adenylosuccinate_synth_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042110">
        <property type="entry name" value="Adenylosuccinate_synth_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042111">
        <property type="entry name" value="Adenylosuccinate_synth_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001114">
        <property type="entry name" value="Adenylosuccinate_synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11846">
        <property type="entry name" value="PTHR11846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00709">
        <property type="entry name" value="Adenylsucc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00788">
        <property type="entry name" value="Adenylsucc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00184">
        <property type="entry name" value="purA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01266">
        <property type="entry name" value="ADENYLOSUCCIN_SYN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00513">
        <property type="entry name" value="ADENYLOSUCCIN_SYN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8 10" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 8 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 8 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 8 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 8 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 8 10" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="IMP binding" evidence="8">
        <location>
            <begin position="13"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="region of interest" description="IMP binding" evidence="8">
        <location>
            <begin position="38"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="299"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="13"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="41"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="140"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="12"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="40"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="303"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="305"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="331"/>
            <end position="333"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="412"/>
            <end position="414"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD90431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="423" mass="46816" checksum="F9BE987808B53E5D" modified="2019-11-13" version="1">MAVDLLLGLQWGDEGKGKIVDVLTTKYNIIARFQGGPNAGHTLEFDGIKHVLRTIPSGIFRKDSMNVIGNGVVIDPVVFVQELEGLDKFNLDYKSKLIISRKAHVILPTHRLLDAASETSKGKAKIGSTLKGIGPTYMDKTGRNGIRIGDLELDNWKDKYRALANKHEGMIAFYDVKVQYNLAEMEAEFFAAVERLKELQFIDSEEYLNQALKDGKSILAEGAQGSLLDIDFGTYPFVTSSNTTASGACTGLGVPPNKIGEVFGIFKAYTTRVGSGPFPTELFDQVGEDMARIGHEFGAVTGRARRCGWLDLVALRYACQVNGVTQLSMMKGDVLSGFTSLKVCTAYHYKGKEIKHFPFNIEAENVTPIYTEFKGWKADLTKMTEASQFPKELNDYIDFLEKELELPITIVSVGPDRTQTINR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMJ7</accession>
    <name>A0A5C6ZMJ7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00165</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046144">
        <property type="entry name" value="DUF6146"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19643">
        <property type="entry name" value="DUF6146"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022747013" evidence="1">
        <location>
            <begin position="22"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="142" mass="16769" checksum="0F9B57C347133778" modified="2019-11-13" version="1">MKKFAFLMSAILILSCVSSNSVTETIGGKTVPKDDVVRIANDDIEYEIIIIEPGFNTWLRSIARPEGYYSQNYMESRNILYVQAWNARVLQGFSYDPNLYIMQIDYQPNIDYGYEVNYQLYNYFIYFQLTYNQRLSTFIPRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMK2</accession>
    <name>A0A5C6ZMK2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF2461 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_05320</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012808">
        <property type="entry name" value="CHP02453"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015996">
        <property type="entry name" value="UCP028451"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36452">
        <property type="entry name" value="PTHR36452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09365">
        <property type="entry name" value="DUF2461"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028451">
        <property type="entry name" value="UCP028451"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02453">
        <property type="entry name" value="TIGR02453"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="221" mass="25636" checksum="C5146B9AE44B0893" modified="2019-11-13" version="1">MLQDKTLAFLTKLKKNNTTEWFKDNQNNYKKSRADFENFVSDIINGLASIDSDIEKQDLQAKKCIKRINRDIRFSNDKSPYKTNYFANFNPNGRKSEHASYYLHLEPNNCFVGGGVYMPQTPTLNKFRKEIEHDLKEWESLLNSKSFKETFPNGIESPSELKTAPKGFDKESPAIEYLRKKGFYTMRKLTDKEITSENAVSKIIEHFGEVKPVIGFLNRAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN18</accession>
    <name>A0A5C6ZN18_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">3-oxoacyl-[acyl-carrier-protein] synthase 3</fullName>
            <ecNumber evidence="7">2.3.1.180</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">3-oxoacyl-[acyl-carrier-protein] synthase III</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Beta-ketoacyl-ACP synthase III</fullName>
            <shortName evidence="7">KAS III</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">fabH</name>
        <name evidence="10" type="ORF">ESY86_04780</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>acetyl-CoA + H(+) + malonyl-[ACP] = 3-oxobutanoyl-[ACP] + CO2 + CoA</text>
            <dbReference type="Rhea" id="RHEA:12080"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9625"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="ChEBI" id="CHEBI:78450"/>
            <dbReference type="EC" id="2.3.1.180"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">The last Arg residue of the ACP-binding site is essential for the weak association between ACP/AcpP and FabH.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the thiolase-like superfamily. FabH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.180" evidence="7"/>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004315">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033818">
        <property type="term" value="F:beta-ketoacyl-acyl-carrier-protein synthase III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01815">
        <property type="entry name" value="FabH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013751">
        <property type="entry name" value="ACP_syn_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013747">
        <property type="entry name" value="ACP_syn_III_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004655">
        <property type="entry name" value="FabH_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08545">
        <property type="entry name" value="ACP_syn_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08541">
        <property type="entry name" value="ACP_syn_III_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00747">
        <property type="entry name" value="fabH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4 7" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2 7" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACP_syn_III" evidence="9">
        <location>
            <begin position="109"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="ACP_syn_III_C" evidence="8">
        <location>
            <begin position="247"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="ACP-binding" evidence="7">
        <location>
            <begin position="264"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="263"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD90070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="336" mass="36796" checksum="615EE347ED6CA53D" modified="2019-11-13" version="1">MYNSKIIGLGHYVPDNVVTNEALSEMMDTNDAWIQERTGIKERRWAVEGSGDTTATMGVKAAKIAIERAGIDKDDIDFIVFATLSPDMYFPGPGVQVQHALDIKTVGALDVRNQCSGFVYAISVADNFIKTGMYKNVLVIGSELHSHGLDKTTRGRGVSVIFGDGAGAAVLSREEDNNKGILSTHLHSQGEHAEELVVKAPGMGTRWVTDILEDNDPNDESYFPHMNGQFVFKNAVVRFSEVIMEGLQKNNLGVDAIDMLIPHQANLRISQFIQKKFKLSDDQVFNNIQKYGNTTAASIPIALTEAWEAGKIKEGDTVVLAAFGSGFTWGSVIIKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNA8</accession>
    <name>A0A5C6ZNA8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Methionine synthase</fullName>
            <ecNumber evidence="5">2.1.1.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">5-methyltetrahydrofolate--homocysteine methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">ESY86_02170</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>(6S)-5-methyl-5,6,7,8-tetrahydrofolate + L-homocysteine = (6S)-5,6,7,8-tetrahydrofolate + L-methionine</text>
            <dbReference type="Rhea" id="RHEA:11172"/>
            <dbReference type="ChEBI" id="CHEBI:18608"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
            <dbReference type="EC" id="2.1.1.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5 7">
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-methionine from L-homocysteine (MetH route): step 1/1.</text>
    </comment>
    <comment type="domain">
        <text evidence="5">Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the vitamin-B12 dependent methionine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.13" evidence="5"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00081"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008705">
        <property type="term" value="F:methionine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042558">
        <property type="term" value="P:pteridine-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02069">
        <property type="entry name" value="methionine_synthase_B12_BD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1240.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.196.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003759">
        <property type="entry name" value="Cbl-bd_cap"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006158">
        <property type="entry name" value="Cobalamin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036724">
        <property type="entry name" value="Cobalamin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011005">
        <property type="entry name" value="Dihydropteroate_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033706">
        <property type="entry name" value="Met_synthase_B12-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011822">
        <property type="entry name" value="MetH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036594">
        <property type="entry name" value="Meth_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000489">
        <property type="entry name" value="Pterin-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004223">
        <property type="entry name" value="VitB12-dep_Met_synth_activ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037010">
        <property type="entry name" value="VitB12-dep_Met_synth_activ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02310">
        <property type="entry name" value="B12-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02607">
        <property type="entry name" value="B12-binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02965">
        <property type="entry name" value="Met_synt_B12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00809">
        <property type="entry name" value="Pterin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000381">
        <property type="entry name" value="MetH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01018">
        <property type="entry name" value="B12-binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47644">
        <property type="entry name" value="SSF47644"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51717">
        <property type="entry name" value="SSF51717"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52242">
        <property type="entry name" value="SSF52242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56507">
        <property type="entry name" value="SSF56507"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50974">
        <property type="entry name" value="ADOMET_ACTIVATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51332">
        <property type="entry name" value="B12_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51337">
        <property type="entry name" value="B12_BINDING_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50972">
        <property type="entry name" value="PTERIN_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5 7" id="KW-0846">Cobalamin</keyword>
    <keyword evidence="4 5 6" id="KW-0170">Cobalt</keyword>
    <keyword evidence="5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="5 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 5 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Pterin-binding" evidence="9">
        <location>
            <begin position="41"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="B12-binding N-terminal" evidence="12">
        <location>
            <begin position="360"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="B12-binding" evidence="11">
        <location>
            <begin position="457"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="domain" description="AdoMet activation" evidence="10">
        <location>
            <begin position="607"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="region of interest" description="Methylcob(III)alamin binding" evidence="7">
        <location>
            <begin position="467"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="7">
        <location>
            <begin position="900"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="404"/>
        </location>
        <ligand>
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="6">
        <location>
            <position position="470"/>
        </location>
        <ligand>
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </ligand>
        <ligandPart>
            <name>Co</name>
            <dbReference type="ChEBI" id="CHEBI:27638"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="515"/>
        </location>
        <ligand>
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="519"/>
        </location>
        <ligand>
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="571"/>
        </location>
        <ligand>
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="657"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="845"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR000381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000381-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000381-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TXD90960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="935" mass="104352" checksum="2041269C12218E5B" modified="2019-11-13" version="1">MLEEDAIKTKVDVAGLRETAVQKYLTLSGLEPLVVTPESNFINVGERTNVTGSKKFLRLIKADNYDEALSVARDQVEGGAQILDVNMDEGMLDGKEAMVKFLNLIASEPDIARIPLMIDSSKWEIIEAGLQVAQGKCVVNSISLKEGETEFKRQATLVKRYGAAVIVMAFDENGQADTYQRRIDICKRSYDILVNEVHFAPQDIIFDPNIFPVATGMDEHRLNALDFFKATKWIRKNLPYANVSGGVSNVSFSFRGNTVVREAINSAFLYHAIQHGMNLGIVNPAMLEVYDEIPKDLLQLVEDVLFDRGEEATQKLLDFAEELMDAPVGTGRDLSVRASAGGFGRVGGRASGRNADRMQLANAWRDASLQERISHALVKGIDGFIIEDVEEARLASGKPIEVIEGNLMIGMNVVGDLFGSGKMFLPQVVKSARVMKKAVAYLQPFIEAEKGGKQEFAGKILMATVKGDVHDIGKNIVSVVLGCNNYEIIDLGVMVPPEKIVETAIRENVDIIGLSGLITPSLDEMVYVSKSLEKQGFKIPLIIGGATTSRAHTSVKIAPNYSNTVVHINDASRAVTVVGDLLNKNNKVYKEQIREEYDKFREQFLKRGKKKDYRTIEDARKRKFEIDWNTSELIKPKHLGIQVLEDFDLKKLEEFIDWSPFFRSWDLHGKYPDILEDEVVGEQAVELFKDAKVLLNRIFDEELLEAKAIFGLFAANSINDDDIEVYGQDGKHDVRFLTLRQQLQKRDGVPNIALADFIAPKSSGKEDYMGCFCVTTGFGCEALAKEFQTNLDDYNSIMIKALADRLAEAFAEYLHKEVRTNHWGYAKNESLSNADLIKESYKGIRPAPGYPACPDHLEKSTIWKLLNVEERIGVKLTESLAMWPSASVSGYYFGNPEAKYFGLGKITDDQLKDYAKRRGISNEEAEKWLSPNLAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNQ4</accession>
    <name>A0A5C6ZNQ4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_05755</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="124" mass="14149" checksum="BAE9FB971FC06445" modified="2019-11-13" version="1">MAFFVLLSTVSFTIGKHFCGDELIDVSVFVQADHCGMAMESDKNLVPEKKSCCNDEFEVVKGQDKLKITKYDDLQFDQQFFLSSFAYPYNKLFEGVPLQIIPHKNYSPPNLIADIQVLDQVFLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNZ0</accession>
    <name>A0A5C6ZNZ0_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">mRNA interferase</fullName>
            <ecNumber evidence="1">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_01885</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Toxic component of a type II toxin-antitoxin (TA) system.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PemK/MazF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="1"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003477">
        <property type="entry name" value="PemK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011067">
        <property type="entry name" value="Plasmid_toxin/cell-grow_inhib"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33988">
        <property type="entry name" value="PTHR33988"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02452">
        <property type="entry name" value="PemK_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF033490">
        <property type="entry name" value="MazF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR033490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="110" mass="12492" checksum="582AB3289ABB556B" modified="2019-11-13" version="1">MRQREIWNVYFDPVQGSEQAGNRPAVIVSGNNLNKNLDVVWVCPLSSSIHKFEGNPILEPDAENGLKLKSEIMIFHLRSISKERFKKKIGSISSKEMDAVFVTINDLMVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZP65</accession>
    <name>A0A5C6ZP65_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Transcription antitermination factor NusB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">nusB</name>
        <name evidence="7" type="ORF">ESY86_00975</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NusB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.940.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035926">
        <property type="entry name" value="NusB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011605">
        <property type="entry name" value="NusB_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006027">
        <property type="entry name" value="NusB_RsmB_TIM44"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11078">
        <property type="entry name" value="PTHR11078"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01029">
        <property type="entry name" value="NusB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48013">
        <property type="entry name" value="SSF48013"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01951">
        <property type="entry name" value="nusB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0889">Transcription antitermination</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="NusB" evidence="6">
        <location>
            <begin position="195"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD91335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="303" mass="35402" checksum="74E02E9F22EB3E9C" modified="2019-11-13" version="1">MQALYASQGSESDDIRVNEKFLLQSLNSMYDLYIAQLSLLLELQKKAEDHLEKSQKKHLATKDEKNPNLKFVNNEVLQLLKNNEALDDVLDNQKVNLWYLDFEYVDILFKALLESDLYKEYMSTKTSTFHEDKLFVIDIFTEIIAPNDKLYDFFEDKRLTWLDDLPVVNTTILKLLKKVKPKSTGKLFTPELFKDLEDRDFGVELLKKTILNQALFMEAIFNKTKNWDADRITLIDRVLMQMAICEFNKFPSIPVKVTINEYLEIAKEYSTPKSSNFINGILDKIVKEYKAEDKLNKIGRGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPV9</accession>
    <name>A0A5C6ZPV9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GreA/GreB family elongation factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_01745</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070063">
        <property type="term" value="F:RNA polymerase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032784">
        <property type="term" value="P:regulation of DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036953">
        <property type="entry name" value="GreA/GreB_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018151">
        <property type="entry name" value="TF_GreA/GreB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001437">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023459">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30437">
        <property type="entry name" value="PTHR30437"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01272">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006092">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00830">
        <property type="entry name" value="GREAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GreA_GreB" evidence="2">
        <location>
            <begin position="91"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="168" mass="18496" checksum="EC8AF6826055C77E" modified="2019-11-13" version="1">MSRGFVKEDDQEEIPMVPPRADLPEGLKNYVTQTGMDQLLAEKEALLSEIKALDSTNEKDKRIAHNLINSKLDLLNERIVSATIIDLSAQPQEEVRFGASITLKIGSNSKTQQFQIVGVDEADIAKGKISFVSPIAKALVNKKVGDTAVLKRPSGDLRYEILGISYED</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZQ54</accession>
    <name>A0A5C6ZQ54_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type 1 periplasmic binding fold superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00185</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023006809" evidence="1">
        <location>
            <begin position="23"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="190" mass="20315" checksum="35DA25B338B0A225" modified="2019-11-13" version="1">MRNYKFLLVAFLSLGLFMGCSNDDDNPEPVNQEEVVTTIRVTLTPAVGGTPIIFEKQDLDGDGPDEPVTTVSGDLMASTIYTGSILLLNETVNPPEVVSEEVQEEDEDHQFFFTFSEESGSVVTYADADGNDNPIGLAFVLTTAQAGSETLTVVLKHEPNKSAAGVSEGDITNAGGETDVEATFNFEVVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZQS7</accession>
    <name>A0A5C6ZQS7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DUF1328 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_01250</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01361">
        <property type="entry name" value="UPF0391"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009760">
        <property type="entry name" value="DUF1328"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07043">
        <property type="entry name" value="DUF1328"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036466">
        <property type="entry name" value="UCP036466"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD91243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="52" mass="5498" checksum="4EF3B93621C13215" modified="2019-11-13" version="1">MLRWTITFIIIAIIAAVLGFGGIAGAAAGIAKIVFFIFIVLFVLSLLKGAFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6Z9Y3</accession>
    <name>A0A5C6Z9Y3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000044">
        <property type="protein sequence ID" value="TXD86648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="268" mass="29679" checksum="898F063F0181B283" modified="2019-11-13" version="1">MKTKMLSIVALSFVLSIGCKENKKTETQTSMATEMENDSTAASITIEKLEGSPKYADASLKMTKPTKMEIDKAGEIDFAFEVNNYELGEQTDSPLAAKLANSDKGQHIHFILDNQPYSAHYESDFKKEMPSGTHYLVAFLSRSYHESVKNENSLVTKKIILGGATDDMNVNFEEPTLIYSRPKGEYSGADTENLLLDFFLLNTTLSDSGNKVRATINGKEFMITEWAPQVIKGLPKGEVTIKLELLDAEGNLLPGGFNEVTRTVTLKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZA56</accession>
    <name>A0A5C6ZA56_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_20285</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000063">
        <property type="protein sequence ID" value="TXD86406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="150" mass="17150" checksum="A492D445EF380EBD" modified="2019-11-13" version="1">MRKIFILKGKSETGKTTKINQIAEWIINNYGCANTIGLNTTNYLKDTHGILTVNKLTIGINSSGDNEWEVKKIDNLSLPNDERPDIILCTCRTKGKGRKHIRDNYNRTNGWLSVFIGVEEFPILDIKNQTTRDTRVIEELKTWLTGLEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZA91</accession>
    <name>A0A5C6ZA91_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4886 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000096">
        <property type="protein sequence ID" value="TXD86055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="96" mass="10738" checksum="347D347CDECEC7F2" modified="2019-11-13" version="1" fragment="single">MKNLLLILITLTTISCKSQNTETTDEINVLFIGNSLTYLHEMPQTVQKMLNETNPNIKIEQSTFPGQSLSGHLSDIITSRTENGISTRKKEDGEKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAL6</accession>
    <name>A0A5C6ZAL6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Group II intron reverse transcriptase/maturase</fullName>
            <ecNumber evidence="2">2.7.7.49</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ltrA</name>
        <name evidence="2" type="ORF">ESY86_20565</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.49" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000088">
        <property type="protein sequence ID" value="TXD86162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003964">
        <property type="term" value="F:RNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030931">
        <property type="entry name" value="Group_II_RT_mat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013597">
        <property type="entry name" value="Mat_intron_G2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000123">
        <property type="entry name" value="Reverse_transcriptase_msDNA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08388">
        <property type="entry name" value="GIIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00866">
        <property type="entry name" value="RNADNAPOLMS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04416">
        <property type="entry name" value="group_II_RT_mat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0695">RNA-directed DNA polymerase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="1">
        <location>
            <begin position="44"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="420" mass="49011" checksum="9244141BC2A7BA8B" modified="2019-11-13" version="1">MIKQLTSKKNLNDAYERVYRNKGSAGLDGVHITGLKSILQSQGKRYIGEIERETFQVSPILGVEIPKSNGKKRLLGIPTVVDRVFQQALHQVVQPIFEPDFQQHSYGSGPERSAHQAIAQSLENINSGYRDIVDIDLKSFFDEVEHYILLELIYKKVKCKPTMKLLRSFLKAPILINGKLHKRKKGVPQGSPLSPLLSNILLNELDKELEKRGHRYVRYADDFSIYVKSEKSAKRVGNSIYKFLKDKLRLPINREKSGIRKPLSFQVLGFGFVPTYKKGEKGTYQLVVKPSKWKEFKAKLKYLTKKTIPASFEERIDRINLLIRGWINYFRPASIQAKLKKLEEWLRNRLRYCIWHHWKKLERKRKNLIRLGIDQEHAYAWSRTRMGGWAVAQSPILRTTITIKRLKMKGYVSLIEYYKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAM8</accession>
    <name>A0A5C6ZAM8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Chloride channel protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_18320</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000031">
        <property type="protein sequence ID" value="TXD87015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005247">
        <property type="term" value="F:voltage-gated chloride channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014743">
        <property type="entry name" value="Cl-channel_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001807">
        <property type="entry name" value="Cl-channel_volt-gated"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00654">
        <property type="entry name" value="Voltage_CLC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00762">
        <property type="entry name" value="CLCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81340">
        <property type="entry name" value="SSF81340"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="62"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="159"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="191"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="233"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="271"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="320"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="350"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="384"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="414"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="7">
        <location>
            <begin position="469"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="7">
        <location>
            <begin position="536"/>
            <end position="593"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD87015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="595" mass="65440" checksum="55E95235EEE5BBBD" modified="2019-11-13" version="1">MPKNPLFKRFLIWRAKHISQKQFVYLLSIVVGFTSGVGAVVLKNATHFIQHLLENKLVQYYHTAFYFVFPIIGFTLVYLIMKYVIRQKVSHGIPSTLFAIAKRKGLMKRYQMFGSILTAPITVGFGGSVGLEGPTVATGAALGSNISRLFHMNQSTRNLLVSCAAAGAMSSIFKAPIAAIIFAIEVFSLDLTIASMLPLLLASLSAILTSFFFFGDDVLLPFKLVDEFNASDAPFYALLGLVAAAVSIYFTEVYDRIQRFFDKIGSPFKRVAFGGICIGILVYLIPPLYGEGFEVINNLVAGNPEKALQNNFLNLDLSSFWVVIALLVGLVFFKIIASALTFGAGGVGGIFAPTLFMGSIMGNCIAKIINHSGWVSTPVSESNFTLVGMAGLLAGVLQAPLTAIFLIAELTGGYDLFIPLMITAAIAFSVTKYFVPHSVYTMELGRKGDLITHNKDHAVLTFMDIDSVIETNFQAISSKMNLGEIVREAVTKSNRNIFPVISEKTKRLEGIILLDDIRSIMFDQTLYDEVKASDVMHNPPDIIDIEKDKMTVIMKKFQDSNAWNLPVVRDGVYIGFISKSKLLTAYRRKLIALTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZB66</accession>
    <name>A0A5C6ZB66_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">IS1595 family transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20745</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000116">
        <property type="protein sequence ID" value="TXD85878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024445">
        <property type="entry name" value="Tnp_ISXO2-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12762">
        <property type="entry name" value="DDE_Tnp_IS1595"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01126">
        <property type="entry name" value="DDE_Tnp_IS1595"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS1595" evidence="1">
        <location>
            <begin position="125"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD85878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="305" mass="35669" checksum="F4424CF4F2964F52" modified="2019-11-13" version="1">MNIFDFGVHFTDEKSCRTHFKEERDKIGVICNRCQGTQHYWLKNKWSYECKSCRSRQSLRSGTIMQGSKLSFLVWYKTIFLLSTTKKGFSSKEIQRQLGLKRYEPVWAMVHKLRKAMGQRDDRYTLEGMIEMDEGYFTIEASQQAHETQKAGRGSKTKSNVMVMAESTVLEDIDTGKVERQCRYFKAKVLDDHKAEGTDQTFVDAIDGERTIVFTDKSTSYVNIADYVEIHVTEKSNEQTTKETLKWVHIAISNAKRNFTGTYHKIKKKYLQLYLNEFVYKLNRRYFGERIFDRLVIASITANGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBC6</accession>
    <name>A0A5C6ZBC6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alanine dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_18940</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000035">
        <property type="protein sequence ID" value="TXD86888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004754">
        <property type="term" value="F:saccharopine dehydrogenase (NAD+, L-lysine-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009085">
        <property type="term" value="P:lysine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007886">
        <property type="entry name" value="AlaDH/PNT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027281">
        <property type="entry name" value="Lys1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05222">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018250">
        <property type="entry name" value="Saccharopine_DH_Lys"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01003">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AlaDh_PNT_N" evidence="3">
        <location>
            <begin position="4"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="90"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR018250-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR018250-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD86888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="401" mass="45067" checksum="61FBF050910B9B8F" modified="2019-11-13" version="1">MKFAIIKERKNPPDRRVVFSPEKLAEAQLQFPNAVFQVEASNIRVFPDAAYEEKGFEVLEDVSDCDVMIGVKEVPIEALVPNKTYFFFSHTIKKQPYNRALLKAILEKNIELYDHETIVAKNNARLIGFGRYAGLVGAYNGFRALGLRDGLFTLPKVETLADLNALKQELDKIKLPNLKILLSGTGKVAHGAKEILDYLNIIEVNDALYLTSEFTEPVYCMVDVMEYNKRKDGTVGDKYEFYADPTGYESNFMPYAKVSDFFIAGHFFGNAAPYLFTRDDAKHPDFKINLIADISCDIDGPVASTIRASTIAAPFYGYDPQSEKEVPFDAKNAITVMAVDNLPCELPKDASEGFGDSFVDEVLPAFFNKDNDGILKRARITKNGKLTKRFKYLQNFVDGKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBF9</accession>
    <name>A0A5C6ZBF9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 12">Aspartate-semialdehyde dehydrogenase</fullName>
            <shortName evidence="12">ASA dehydrogenase</shortName>
            <shortName evidence="12">ASADH</shortName>
            <ecNumber evidence="7 12">1.2.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Aspartate-beta-semialdehyde dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">asd</name>
        <name evidence="14" type="ORF">ESY86_18230</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the NADPH-dependent formation of L-aspartate-semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl-4-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>L-aspartate 4-semialdehyde + NADP(+) + phosphate = 4-phospho-L-aspartate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:24284"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57535"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="1.2.1.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 12">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 2/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 2/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 12">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6 12">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 12">Belongs to the aspartate-semialdehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.11" evidence="7 12"/>
    <dbReference type="EMBL" id="VORO01000030">
        <property type="protein sequence ID" value="TXD87071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00016"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00463"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00464"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004073">
        <property type="term" value="F:aspartate-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071266">
        <property type="term" value="P:'de novo' L-methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019877">
        <property type="term" value="P:diaminopimelate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02121">
        <property type="entry name" value="ASADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012080">
        <property type="entry name" value="Asp_semialdehyde_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005986">
        <property type="entry name" value="Asp_semialdehyde_DH_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000534">
        <property type="entry name" value="Semialdehyde_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012280">
        <property type="entry name" value="Semialdhyde_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01118">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02774">
        <property type="entry name" value="Semialdhyde_dhC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00859">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01296">
        <property type="entry name" value="asd_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 12" id="KW-0220">Diaminopimelate biosynthesis</keyword>
    <keyword evidence="10 12" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="11 12" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="12" id="KW-0521">NADP</keyword>
    <keyword evidence="12 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0791">Threonine biosynthesis</keyword>
    <feature type="domain" description="Semialdhyde_dh" evidence="13">
        <location>
            <begin position="2"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="12">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="12">
        <location>
            <position position="234"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="9"/>
            <end position="12"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="37"/>
            <end position="38"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="307"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TXD87071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="329" mass="36207" checksum="E7549AFF62E55020" modified="2019-11-13" version="1">MKIAVVGATGLVGQVMLKVLEERNFPLTDLIPVASERSVGKIIQFKGKDYKVVSLQTAIDLKPNVALFSAGGDTSLEWAPKFAAAGITVIDNSSAWRMDHNKKLVVPEINASQLTKNDKIIANPNCSTIQMVLALAPLHKAYKIKRVVVSTYQSITGTGVKAVKQLENEMAGIKGEMAYHYPIHQNAIPHCDVFEENGYTKEEMKLVRETQKILDDKTIAVTATAVRIPTAGGHSESVNVEFEKDFDLNTVRKLLNDSPGIVLQDNIDVNMYPMPIYANGKDDVFVGRIRRDGSQPNTLNMWIVSDNLRKGAATNTVQIAEYLLEKGLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBN8</accession>
    <name>A0A5C6ZBN8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_16775</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000024">
        <property type="protein sequence ID" value="TXD87433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="77" mass="9119" checksum="3208FF13CF49774A" modified="2019-11-13" version="1">MNLETRKIEFVQEFLKLQSEDAIARLEKLLEQQKMTPDQKRVAPMTQAELNKRIDQSESDFLNNRYKSSAELLAKYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBR7</accession>
    <name>A0A5C6ZBR7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Isoaspartyl peptidase/L-asparaginase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_18190</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000030">
        <property type="protein sequence ID" value="TXD87063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000246">
        <property type="entry name" value="Peptidase_T2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10188">
        <property type="entry name" value="PTHR10188"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01112">
        <property type="entry name" value="Asparaginase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="252"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="275"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="224"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage; by autolysis" evidence="3">
        <location>
            <begin position="223"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600246-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR600246-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600246-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD87063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="358" mass="38009" checksum="B2A3A3817771A236" modified="2019-11-13" version="1">MRNPIFFLALFSLCLSCGEMDSNANTTAKASDDKPSEVTQKAEFAIIIHGGAGNILKKNMTSEDEAAYKAKLEEAIRVGYEILKNGGSSLDAVQKTINVMEDSPLFNAGKGAVFTNAETNELDASIMDGKTLNAGASAGTTTVRNPINLARAIMDNSPHVMMAGTGAETFAKEQGLDIVSPSYFYTENRFKSLQRIKASEKTEGDHDNNQAFYDPTIKDSKFGTVGCAALDKDGNLAAGTSTGGMTNKRYGRVGDAPIIGAGTYANNNSCAVSSTGWGEYFIRAMVAHDISALMQYKGMSLAEAAREVIQKKVPDLGGDGGIIAVDKNGAMVAEFNTAGMYRATMNDKGELEIGIYGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBZ0</accession>
    <name>A0A5C6ZBZ0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18955</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000035">
        <property type="protein sequence ID" value="TXD86891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038489">
        <property type="entry name" value="SUFU_C_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="78" mass="9098" checksum="AC3F7E9D70577624" modified="2019-11-13" version="1">MEPLKILIFNRFKILSILFAAMALSMLLLMIRMKLNQSFHFLFLVWNLFLALIPFAITTALASGKKPYKLYFLVVFLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC57</accession>
    <name>A0A5C6ZC57_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Sulfotransferase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_18735</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000033">
        <property type="protein sequence ID" value="TXD86970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="221" mass="25672" checksum="046876DD1CBDAE34" modified="2019-11-13" version="1">MYSFAQRLDTKVFDEPLYAYYLRNSNAKAYHPGAKDILATMENDGNSVVDMMLKSNEKPVLFFKNMSHHLLNLDYSFMKQMTNVILTRDPLEMLPSFAKVIENPSLDDVGYKLHVDLIAYFETHQIKYVVLDGKNLLLNPEGVLRQLCEKIDIPFDHAMLSWAPSKREEDGIWEKYWYKSVHESSGFGVYESKSEIFPKHLNPLLLQCQSYYEQLKALALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC76</accession>
    <name>A0A5C6ZC76_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">RloB domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_20015</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000054">
        <property type="protein sequence ID" value="TXD86518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025591">
        <property type="entry name" value="RloB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13707">
        <property type="entry name" value="RloB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="209" mass="24461" checksum="DEFC38A129A7FBB1" modified="2019-11-13" version="1">MKRGFRKSRVTIKFSRRGLILCEGETEENYFTGLVTQEKYRRKFSSIDVQIVKPKDHSPLGLVNEAKLKIKEAKREKNPYDFIWVIFDRDGHAKIPEAFETARTSTPEIKIVYTKPCFEFYVLLHFEKTTKPFTKCDDVISYINKKYQVDYKKASNLFDLLLTQKETGLSNGDWVVNQFEDEIASGKKIYELSAFSNVHVLVEYLYSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC98</accession>
    <name>A0A5C6ZC98_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidoglycan glycosyltransferase</fullName>
            <ecNumber evidence="1">2.4.1.129</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">ESY86_16425</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>[GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate = [GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23708"/>
            <dbReference type="Rhea" id="RHEA-COMP:9602"/>
            <dbReference type="Rhea" id="RHEA-COMP:9603"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58405"/>
            <dbReference type="ChEBI" id="CHEBI:60033"/>
            <dbReference type="ChEBI" id="CHEBI:78435"/>
            <dbReference type="EC" id="2.4.1.129"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.129" evidence="1"/>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008955">
        <property type="term" value="F:peptidoglycan glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3810.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001264">
        <property type="entry name" value="Glyco_trans_51"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036950">
        <property type="entry name" value="PBP_transglycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00912">
        <property type="entry name" value="Transgly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="domain" description="Transgly" evidence="10">
        <location>
            <begin position="70"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="9">
        <location>
            <begin position="415"/>
            <end position="661"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD87615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="764" mass="86191" checksum="93D0893FE2F095F6" modified="2019-11-13" version="1">MKFKLKRSWLKWFFGIIGSGFLLLLLFWFSVYVGLWGKLPSKENLADIKQAEASILLDANEKLLGKYFIFDRQMVHYEDLPKHLVNALVATEDARFYEHGGVDYTSLFRVLFKSILLQDDSAGGGSTISQQLVKNLYGRPSHGWFTMPVNKIKEMIVAKRIEAVYSKKDILTLYLNTVPFSENTFGIESTSQKFFSTSTRNLSLSQAATLVGSLKASHSYNPRLFPERSQLRRDVVLQQMAVNGYIDETLQKKTNSEPLEINYRIFKHDDGMAAYFREKVRLDVVKILDSIKGPGGKTYDLYKDGLKIQTTLDIDMQRYAENAMQQHLEKLQKQFEDSYGSNAPWLKNEDLVTSRIQELDLYKALKKQKYSEAKIMDSLNTKGQYKLFRWEGDTIVNCTVIDSIKHGLQFLNTGFIALQPQTGAIKAYIGGIDYEYYKYDHVYKAKRQVGSTFKPIVYTAAIENGMDACSYLPVKAMTYTNEKDWKPTNSGTAETDEHLNYSLEYGLSNSVNTIAVKVLEEVGIAKTIAQAEKMGISSELPKVPSLALGTAELSLLELASAYTSYVNNGRASVPFYITKIKDKNGNIIYAPEAKAALPEAFSEETRQIMVEMMKATVNKGTAQRLRSTYGLQNDLAGKTGTTQNNKDGWFVGVSPNLVMATWVGNDEHRIGFKSTGLGQGANSALPMVALFLKQMNGDSKFNAITQAKFENPSEAVIAALDCDPEKRDGFLKRLFTKERDQKEFDEADKKDEDKGFFSFLKKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCB6</accession>
    <name>A0A5C6ZCB6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19440</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000040">
        <property type="protein sequence ID" value="TXD86747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="212" mass="24837" checksum="75BEADDF17A3147E" modified="2019-11-13" version="1">MSKKHKDFFWMSFSDLMTSLFFVVLVLYVLTYVMLKDALQKANTTIEEQNKILQLKEQFKPLQEDKDFIYLADCKKYISKELNSIEIFEPNKSAILEKYESSTIKVGNKLEELLKNLNAANVNFSYLIIIEGNMANSWDKRFSSDSEYGYKKSYERALAVYNLWSNNNIDLRKYNSEILISGSGFNGLCRDKVEENNKRFSIQIIPKIEYSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCB9</accession>
    <name>A0A5C6ZCB9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cell filamentation protein Fic</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_19825</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000049">
        <property type="protein sequence ID" value="TXD86590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003812">
        <property type="entry name" value="Fido"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036597">
        <property type="entry name" value="Fido-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040198">
        <property type="entry name" value="Fido_containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13504">
        <property type="entry name" value="PTHR13504"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02661">
        <property type="entry name" value="Fic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140931">
        <property type="entry name" value="SSF140931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51459">
        <property type="entry name" value="FIDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fido" evidence="3">
        <location>
            <begin position="322"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="396"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="400"/>
            <end position="407"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD86590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="493" mass="56063" checksum="092A59D53FAC2735" modified="2019-11-13" version="1">MEKNGQLHLQEIIYGSADSTISRQISKLEKEGKIRKIASRIYTSNFEDTPENIIQRNIFPILGNQYPGAVLSHRSAFEFEPTSSGQVFVTYKYTKKIKLPGITIRFMDGWAATDGDTSFSGELMVSQRERALLENLQVSRQVGADSKTLTYPQIEEKLEKIIRVNGEKELNLVRDRAREISEEIGMQKEFEKLNKIIRALLATHPSSALKSSVAAARAQGLPFDPARMQLFETLFRALKQEEFKYREEQNTTTSAYRNFAFYESYFSNYIEGTVFELDIAKQIIATQQPLPARNEDSHDVLGTYQLASSKQEMKIVPYSGENFLDILQYRHAILFSAREDKKPGKFKDKNNQAGNTSFVDMELVKGTLLQSFNFYNALVHPFAKAAYIMFVISEVHPFLDGNGRMARIMMNAELSSAGQTKIIIPTVYREDYLGGLRRLTRQNDPSVYIRMLERAQAFSHTLQGVDMEAIENVLRQSEAFKEGNEGVLKIIAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCE8</accession>
    <name>A0A5C6ZCE8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000045">
        <property type="protein sequence ID" value="TXD86640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022759888" evidence="1">
        <location>
            <begin position="20"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="268" mass="31930" checksum="8451CE135E418CF5" modified="2019-11-13" version="1">MKKILLILTFFTLMTKLSAQECEYSEYYPLVELASKYYSQKNYKESEINFKLAFDKTEFPLGKDLHLAFLIAEKIKDAEWALQIATQLAKGGVPLSYFRYYKKTQWYSQLNAEYKTYSDYYITNFKPELRDKFNSLIERDATFTRQIMDWYYGTIEITSENAYNEANAIYSELKQMTEKYGFPSEHNMGYNYVSRLNKIEDYHTLALMIHIYKYGERIYENEIPNYICSGILHPNSKQILKQSMGFGNSMGIEHEMKVREEMYKKKKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCF6</accession>
    <name>A0A5C6ZCF6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19615</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000044">
        <property type="protein sequence ID" value="TXD86651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022751222" evidence="1">
        <location>
            <begin position="21"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="147" mass="16579" checksum="747F08314F1852F7" modified="2019-11-13" version="1">MKTNLIIAILLCWFSATALGQQKITWKTLSDVSFADEYFPEEDTYFLTPTFGASLHKLQNVEIIIKGYILNIDPSSRVYLVSENPMASCFFCGMGGPETIMEVRFTKKLSFKTDDIVTITGTFKLNGDDINHCNYILENATGRLENN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCJ8</accession>
    <name>A0A5C6ZCJ8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_15735</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007492">
        <property type="entry name" value="LytTR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04397">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00850">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50930">
        <property type="entry name" value="HTH_LYTTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="3"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="HTH LytTR-type" evidence="3">
        <location>
            <begin position="139"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD87761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="241" mass="27766" checksum="5E644F1EE9D899DC" modified="2019-11-13" version="1">MNSYFVIDSDGKIAKDLKKVMADYPMFLSIGNSNSYEQSMNIILKRKPDLVFLNLDNVIESPFELVTELNSYLEIIPDFVAVSSSNENSYKALKHGFIDYLMTPLVELEIRKLALKFKKKQSSKTNRTLCLQSYKDFQYLNTDEILFLKADNNTTDFYLNDGSVISAFKTLKIFENALPNNFLRIHKSYVVNKDYVSRINYGNLKCSVINTVQKIPFTKTYLSNIEFIKDSLSDLSIQSQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCX5</accession>
    <name>A0A5C6ZCX5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_14760</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="440" mass="51587" checksum="C78A460A38791061" modified="2019-11-13" version="1">MLLVYTHKITPRVQYAFKHLCTRILGIPVSFTTTIEEFIAHDSIKMSYTKKALSNEIFVKSHELLFEQGLSDVEINVQEWYGTKCFFPAGENSALPYDIFAAAFYLISRYEEYLPHVKDDYGRFTATESLAFKEGFLHQPVVDIWAYRLKTVLEQKFENFKFPKQIYKVQPIIDVPVAYLFKQKGLMRIIGGTLNEVFNLKLKQLSQRFLVLFGFKRDPYDTFKWIINKQKQYKFKFIVFFLIGDFSTYDKNVNVNKKEFVSLIKSVGDYCKVGLKVSFLALEDILRLKKEKKKMESITNYELEATRNSFSKINLPHSYRNLVELEIKQDYTMGYLNYMGFRAGTCTPFLYYDLDYEIRTPLIINSFHCIDHALLKHQSQLDKSEALERMIKEVKKVNGTFTPVFHNYSFGDEPTWKGYRKLFTQILNSVEGGNIPKKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCX9</accession>
    <name>A0A5C6ZCX9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_18555</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000032">
        <property type="protein sequence ID" value="TXD86994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="216" mass="24958" checksum="3CCDCE14D0499B25" modified="2019-11-13" version="1">MKTFKDLIIKNNSQTELEDILNKVILSSPPEWIFLEELASDYSKNVSKPKEQISCFESPEINGVKGYVWFVIWENELKVNNIVPTKSGSLSFDEYNGILDEFYEKCIKPITIGADSSLTISEGKFNIEIIAGTTVFESLKKWEKSCNHSTGNTHPMDFERWANFLCISFKEKSKLTPDLLQRWLFEACDWNDDELVSKIVIDYEYGISILEHYVNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCZ5</accession>
    <name>A0A5C6ZCZ5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA recombination protein RmuC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rmuC</name>
        <name evidence="4" type="ORF">ESY86_17005</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in DNA recombination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RmuC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000025">
        <property type="protein sequence ID" value="TXD87370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003798">
        <property type="entry name" value="DNA_recombination_RmuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30563">
        <property type="entry name" value="PTHR30563"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02646">
        <property type="entry name" value="RmuC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="70"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="157"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD87370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="463" mass="53094" checksum="F3A679E3CB00B875" modified="2019-11-13" version="1">MTDSIILLLTILISAALGAYLGMRFNALKSKSEQSTLEERNINLSQQLQENKVQHATESQSQEANYKAKMAEYAEAISKIELDREDIRREKEFLGNELARKTTEFNNLQNRYTQREEEVELRQIQLRKDFELLATKILDEKSEKFTLQNKENIKNILSPLQEKIQTFEKKVDDTQKESISMHSALKEQLLGLKDLNQQMSKETSNLTKALKGDSKMQGNWGELVLERVLEKSGLEKDREYFVQQSFTRPDGTRVLPDVVLNLPNNKKMIIDSKVSLTDYERYVNADEDQRPLFLKAHINSLKRHVDQLSEKNYHDLYDMESPDFVLLFVPIEPAFAIAINAENALYTSAFEKNIVIVTPSTLLATLRTIDTMWNNEKQQRNAIEIARQAGALYDKFEGLVKDLTGVGKKMDDAKKDYSSAMNKLVEGRGNLISSVQKLKRMGAKAKKSLPETIIDQAMDDEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCZ7</accession>
    <name>A0A5C6ZCZ7_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Aspartate--tRNA ligase</fullName>
            <ecNumber evidence="7">6.1.1.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Aspartyl-tRNA synthetase</fullName>
            <shortName evidence="7">AspRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">aspS</name>
        <name evidence="9" type="ORF">ESY86_18315</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + L-aspartate + tRNA(Asp) = AMP + diphosphate + L-aspartyl-tRNA(Asp)</text>
            <dbReference type="Rhea" id="RHEA:19649"/>
            <dbReference type="Rhea" id="RHEA-COMP:9660"/>
            <dbReference type="Rhea" id="RHEA-COMP:9678"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78516"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.12" evidence="7"/>
    <dbReference type="EMBL" id="VORO01000031">
        <property type="protein sequence ID" value="TXD87014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004815">
        <property type="term" value="F:aspartate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006422">
        <property type="term" value="P:aspartyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00044">
        <property type="entry name" value="Asp_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004524">
        <property type="entry name" value="Asp-tRNA-ligase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004115">
        <property type="entry name" value="GAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029351">
        <property type="entry name" value="GAD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22594:SF5">
        <property type="entry name" value="PTHR22594:SF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02938">
        <property type="entry name" value="GAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55261">
        <property type="entry name" value="SSF55261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00459">
        <property type="entry name" value="aspS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="8">
        <location>
            <begin position="144"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Aspartate" evidence="7">
        <location>
            <begin position="198"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="220"/>
            <end position="222"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="445"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="479"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="486"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="531"/>
            <end position="534"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD87014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="584" mass="66430" checksum="A98D75BA7583EE2F" modified="2019-11-13" version="1">MYRSHNCGELSASHIDTEVTLAGWVQKSRNKGFIVWVDLRDRYGITQLVFDEDRTPKEMMARAEELGREFVIQVKGKVIERASKNPNMATGDIEILVSELTILNESKLPPFTIEDNTDGGEELRMKYRYLDIRRNPVKNNLIFRHKVTQAVRNYLSTEGFIEVETPYLIKSTPEGARDFVVPSRMNEGQFYALPQSPQTFKQLLMVGGMDKYFQIVKCFRDEDLRADRQPEFTQIDCEMAFIDQEDILNAFEGLTRFLLKEINGVEVEKFPRLLYDDAMRLYGNDKPDIRFGMKFGELNAVAQHKDFNVFNAAELVVGIAVPGGNTYTRKEIDKLIEWVRRPQVGALGMVYCRYNDDGSYKSSVDKFYDQEDLAKWAEATGAQPGDLICVLSGDKHKVRAQLSALRMELAERLGLRNPKEFAPLWVMDFPLLEWDEDTKRYHAMHHPFTSPKPGQLDLLKTNPGEVKANAYDLVLNGNEIGGGSIRIHDKETQALMFEYLGFTEAEAKAQFGFLMDAFQYGAPPHGGLAFGLDRLVAILGGQETIRDFIAFPKNNNGRDVMIDAPAKIDEAQLKELSLKLDLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD29</accession>
    <name>A0A5C6ZD29_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MoxR family ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_18135</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000030">
        <property type="protein sequence ID" value="TXD87054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011703">
        <property type="entry name" value="ATPase_AAA-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041628">
        <property type="entry name" value="ChlI/MoxR_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07726">
        <property type="entry name" value="AAA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17863">
        <property type="entry name" value="AAA_lid_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_3" evidence="1">
        <location>
            <begin position="53"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="AAA_lid_2" evidence="2">
        <location>
            <begin position="258"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="333" mass="37439" checksum="CEFB1C3FA443B5FE" modified="2019-11-13" version="1">MEEHATIDINAINQKIEKESAFVDLLMMEMNKVIVGQKHMVERLLIGLLGRGHILLEGVPGLAKTLAINTLSQAVDASFSRIQFTPDLLPADVVGTMIYNMKLNDFSIKKGPIFANFVLADEINRAPAKVQSALLEAMQEKQVTIGDETFILDKPFLVMATQNPVEQEGTYPLPEAQVDRFMLKTVIDYPKLAEEQLIMRANLKGAWEKVNPVISVSQILRAQEVVREVYMDEKIEKYILDIVFATRYPEQYKLSALKPLISFGASPRGSINLATAAKCYAFIKRRGYVIPEDVRAIVYDVLRHRIGLTYEAEAENVTSEDIISKIINEIEVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD60</accession>
    <name>A0A5C6ZD60_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Sulfotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_16885</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000024">
        <property type="protein sequence ID" value="TXD87454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="325" mass="38166" checksum="D7BDCF3F1F497A36" modified="2019-11-13" version="1">MDESKLIFIISQPRSGSTYLQNLLSNNNQVNTCSEPWILLNFSSLIKPELIQATYNHKLANEAFKDFIGKYPSIKFTTGLKEMILDMYQPMAEGFDYVIDKTPRYWEMMDEIVEWFPKSKIIILKRHPVDVATSIIKTWNIKKLTMLSRFQRDLLLAPEHLHLFSNKHQSNPQVFTLKYEDLQNNKVVEIRNLYSWLGLDYHEAVLNAETNKKHKGMFGDPFQNKLEKSEETVQLIKSAKLSKDFEEFIIGYKHYLTPEFMESYGNYKLDKGRETKIFGKFLLFSNDVNALNNKFLQIKYSTSYKVGKMILYPIVTFKRFLSGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD89</accession>
    <name>A0A5C6ZD89_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Type I site-specific deoxyribonuclease</fullName>
            <ecNumber evidence="3">3.1.21.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">ESY86_17990</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endonucleolytic cleavage of DNA to give random double-stranded fragments with terminal 5'-phosphates, ATP is simultaneously hydrolyzed.</text>
            <dbReference type="EC" id="3.1.21.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HsdR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.21.3" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000029">
        <property type="protein sequence ID" value="TXD87120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009035">
        <property type="term" value="F:type I site-specific deoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007409">
        <property type="entry name" value="Restrct_endonuc_type1_HsdR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040980">
        <property type="entry name" value="SWI2_SNF2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04313">
        <property type="entry name" value="HSDR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18766">
        <property type="entry name" value="SWI2_SNF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 13" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0680">Restriction system</keyword>
    <feature type="domain" description="HSDR_N" evidence="11">
        <location>
            <begin position="8"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="domain" description="SWI2_SNF2" evidence="12">
        <location>
            <begin position="249"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF04313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF18766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TXD87120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="353" mass="40344" checksum="B283290866679166" modified="2019-11-13" version="1">MAWLTDKQLDDLYNETIAAEKANLSLLEANKQVFEKLIGVTKTTVAKNEVTGEENPLVKLIDFKHWDNNEFVAINQFRIVTPGGPREGIIPDIVLFVNGLPFSVVECKDVDVADPISSSVEQLMRYANTRGDDFGFTDGEERLFHYNLFSVATHGEEARAGSISGDFEYYLNWKDIFPEVYKNIDVERYAAEETARYQNNGLQSDPRVRQEVLIQGLLNKEILLDVLQHFTLFMEIKEGVEFKIVCRYQQYRAVGKIIDRLRNETTGKTRSGVVWHTQGSGKSLTMVFFVRKLRSQDDLKDYKVIMMVDRKDLEKQLSATARLTNEFKLLFPAVECTGTHTVFTAALNDPYLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD91</accession>
    <name>A0A5C6ZD91_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RDD family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_15925</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000021">
        <property type="protein sequence ID" value="TXD87648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010432">
        <property type="entry name" value="RDD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06271">
        <property type="entry name" value="RDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="RDD" evidence="6">
        <location>
            <begin position="19"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD87648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="247" mass="28578" checksum="F7ED7ADF88859F90" modified="2019-11-13" version="1">MVELQINTTQNVNINFIAASVGERILAFIIDLIIKVAYAVVTYQIMFKLFQIDEMVMEMDQWSQMAVYGIFFLPIVFYSLVFETWLDGQTPGKRIMKIKVVKIDGYQASLADYMIRWFFRIIDLNMFSGVVALIAIVTSKKSQRLGDMTAGTSVITLKNKININHTILEELDDDYVPTYPNVIKLSDNDARIIKETFIKAKASRDYETLVKLRKKVVEVVGIKDYNDHDIKFIDVILKDYNYYTQSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDC9</accession>
    <name>A0A5C6ZDC9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18215</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000030">
        <property type="protein sequence ID" value="TXD87068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="145" mass="16662" checksum="F1BC765D72DBE66F" modified="2019-11-13" version="1">MYTTVNFIHSYWAYLVLLMLVVATFNALIKYFGKKEFQPQDFRIALFTLIVTHIQLLIGIVLFFAADYISVISNLGMGGLMKNDTLRSNIIEHPLTMIIAVVLITIGYSKHKKKLTSTPKFKMLAIFYTLALILVLAKIPWKVWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDH7</accession>
    <name>A0A5C6ZDH7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_16240</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="214" mass="24999" checksum="D08F9961DEBBC605" modified="2019-11-13" version="1">MKTNFCFSACLFVLILSCNSKPKSFFWKGVVSDSTQVYIAYRGTNTKQGFLANDFNMKDSLSSHVGLLLSKNNNWQVYNVIETKDSLSDFKEQSLEQFYDVDKEKIFYASFWKIKHIDSLNLSKLKELIGIYEAKNIIFDKSISLNDSTKLYCSEFIRNILYETDSTLFDINPVKIGLKGLYKAYFRSDTLEYYPVDIFQQDSNFSKVKEWNFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDH9</accession>
    <name>A0A5C6ZDH9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000027">
        <property type="protein sequence ID" value="TXD87245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022973337" evidence="1">
        <location>
            <begin position="24"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="245" mass="27917" checksum="AC554A1D7551ECF5" modified="2019-11-13" version="1">MKTLKTSFFALSLLLMLPMISQSQEQESFIMNLTEFTIKYGHDGNFKEGVKKWNKCYKDNNGTDTWNVWHRLQGKGNVYVLSGNMANWAEMDKEDAAGKACRAVGLEYITPHIESTAFNMARPMPEISRKAPLGDMSIVWVTSFKVQNDAAFNEVIKDVMSTMSSKEGESKSYWYSVMGGEDSDYFVSTPFKDFAALDVESDGVWKIYESVHGKAKTKETRTKLRASVDNIWDYTYTLDKEISMQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDY0</accession>
    <name>A0A5C6ZDY0_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Nicotinate-nucleotide diphosphorylase (carboxylating)</fullName>
            <ecNumber evidence="4">2.4.2.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Quinolinate phosphoribosyltransferase [decarboxylating]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">nadC</name>
        <name evidence="13" type="ORF">ESY86_17245</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in the catabolism of quinolinic acid (QA).</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from quinolinate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the NadC/ModD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.19" evidence="4"/>
    <dbReference type="EMBL" id="VORO01000026">
        <property type="protein sequence ID" value="TXD87308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00331"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004514">
        <property type="term" value="F:nicotinate-nucleotide diphosphorylase (carboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01572">
        <property type="entry name" value="QPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004393">
        <property type="entry name" value="NadC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027277">
        <property type="entry name" value="NadC/ModD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036068">
        <property type="entry name" value="Nicotinate_pribotase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037128">
        <property type="entry name" value="Quinolinate_PRibosylTase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002638">
        <property type="entry name" value="Quinolinate_PRibosylTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022412">
        <property type="entry name" value="Quinolinate_PRibosylTrfase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32179">
        <property type="entry name" value="PTHR32179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01729">
        <property type="entry name" value="QRPTase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02749">
        <property type="entry name" value="QRPTase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006250">
        <property type="entry name" value="NadC_ModD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51690">
        <property type="entry name" value="SSF51690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00078">
        <property type="entry name" value="nadC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9 13" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9 13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="QRPTase_N" evidence="12">
        <location>
            <begin position="23"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="QRPTase_C" evidence="11">
        <location>
            <begin position="114"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="135"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="247"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="268"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR006250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR006250-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TXD87308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="286" mass="31340" checksum="E9E1EFF404D48DFB" modified="2019-11-13" version="1">MISKAQFNTEIELIIANAIREDVGDGDHSSLACIPATAQGKAKLLVKDKGIIAGVEFAKQVFAHIDKDLKVETLINDGDQVKQGDIVFYVEGASQSILKAERLVLNAMQRMSAIATKTKSFVALLEGTGTKILDTRKTTPGIRALEKWAVKIGGGENHRFALYDMIMLKDNHIDFAGGISKAIEKTKQYLKDTGRDLKIIVEARNLEEIKAILKAKGVYRILIDNFNYEDTRAAVKLIGDQCLTESSGGINEKTLRTYAECGVDYISSGALTHSVYNMDLSLKAVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE59</accession>
    <name>A0A5C6ZE59_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA polymerase sigma factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_17185</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000025">
        <property type="protein sequence ID" value="TXD87403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="27"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="3">
        <location>
            <begin position="125"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD87403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="187" mass="22040" checksum="0327732CAACDD171" modified="2019-11-13" version="1">MTLTHQDISQLILHCKNGDQQAQLEVYNRYYRAMFNTAFRIVKDRFEAEDIMQDSFLSAFTKLESLKELSTFGAWLKRIVINNSIYHYKKNSKYRDVPLDEVIYKIEDDSQGFCEDHDFSNLKAQQVLATMKSLKANYQMSLSLHLIEGFDYEEICEIMDISNANCRTMISRAKEKLRQKLEEMADF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEA7</accession>
    <name>A0A5C6ZEA7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_13635</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="71" mass="8147" checksum="5B07636B36CF1BE4" modified="2019-11-13" version="1">METLSINILNPKAKKLLKDLADLKLIKINNVSKKSDFSKLLEKLRTKSEESLSIAEITKEVEAIRTSRYEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEI8</accession>
    <name>A0A5C6ZEI8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Patatin-like phospholipase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_15015</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="1 2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="3">
        <location>
            <begin position="4"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXGXXG" evidence="2">
        <location>
            <begin position="8"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="2">
        <location>
            <begin position="36"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="2">
        <location>
            <begin position="182"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="38"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD87978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="303" mass="34206" checksum="622B3A4AA2C0325E" modified="2019-11-13" version="1">MRALVISGGGSKGAFAGGVAQYLMEKKGHKYDLFIGTSTGSLLVSHLALQKVEKIKRVYTNVNQNSIFNVCPFYIKRKKGVETIGINHFNVLLNLLRGSKTFGESYNLKALIKDTITIAEFETLKQMDVDIVVTVSNLSLNEVEYKSINDFDYEDFCEWVWISCNYTPFMSLVTKNGCEYADGGLGSMVPIEEAIKRGATVVDAIILQTEVTQFNRMPSLNAFSLMTNMFAFMVDRIENSNIRIGKFVATNNDAIINFYYTPTVLTTNSLVFRKDKMTQWWERGVNYAKLKDQESSQINTNLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEU2</accession>
    <name>A0A5C6ZEU2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Energy transducer TonB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_14480</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037682">
        <property type="entry name" value="TonB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03544">
        <property type="entry name" value="TonB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_C" evidence="3">
        <location>
            <begin position="197"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="267" mass="30316" checksum="38F32CF4188E738F" modified="2019-11-13" version="1">MRNPKETHNIADQSNDKVRKSQKHDANLQKNSALYFQVGLILCLLATYGLFELKFEKSTYNPDYVLSALPNDTMVDAVNIIPEESIATKKKDIISEPIVEDPNLKIVDNATPIIDENEFLYESQPNSDPVDPNSLGKIEKPNDINSDELFDMHDVEIVPIYPGCEKMMTNETRVKCMSEKLTRLIQNKFDTGLALELGLTGTQRINVQFKIDKQGRITDVLTRAPHPELEKEAKRLTAKIPTMEPGLQRHKPVSVLYNLPIVFRVQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEV2</accession>
    <name>A0A5C6ZEV2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribosome-associated translation inhibitor RaiA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">raiA</name>
        <name evidence="2" type="ORF">ESY86_17255</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000026">
        <property type="protein sequence ID" value="TXD87310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044238">
        <property type="term" value="P:primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00552">
        <property type="entry name" value="RaiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036567">
        <property type="entry name" value="RHF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003489">
        <property type="entry name" value="RHF/RaiA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02482">
        <property type="entry name" value="Ribosomal_S30AE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69754">
        <property type="entry name" value="SSF69754"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00741">
        <property type="entry name" value="yfiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0810">Translation regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="99" mass="11655" checksum="E6EB65DDC20F70DB" modified="2019-11-13" version="1">MTVNFQYVDVDVSESLSAFTEEKLDKLFNRYEFIVGADVFFKKDTNEPEKNKICNIRLSLPGPRLFATSSEKQYEVAVRETICDLERQLKKRKEIFKTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEV3</accession>
    <name>A0A5C6ZEV3_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_12270</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Responsible for synthesis of pseudouridine from uracil.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a uridine in RNA = a pseudouridine in RNA</text>
            <dbReference type="Rhea" id="RHEA:48348"/>
            <dbReference type="Rhea" id="RHEA-COMP:12068"/>
            <dbReference type="Rhea" id="RHEA-COMP:12069"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pseudouridine synthase RluA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120159">
        <property type="term" value="F:rRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd02869">
        <property type="entry name" value="PseudoU_synth_RluA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006225">
        <property type="entry name" value="PsdUridine_synth_RluC/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluC/D_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00005">
        <property type="entry name" value="rluA_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S4" evidence="5">
        <location>
            <begin position="30"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR606225-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD88513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="344" mass="39418" checksum="FA0B75E04D0E14D2" modified="2019-11-13" version="1">MTTEDSTIDEQDDELFEHHSFTADKGQSPLRIDKYLMNRIENATRNKIQSAAKDGSIFVNDIPVKSNYKVKPKDHIRVLLEYPPYENLLTPENIPLDIVYEDEVLLVVNKPAGMVVHPGHGNYSGTLINALVYHFDNLPNNSSDRPGLVHRIDKDTSGLLVIAKTEQAMAHLAKQFFNKTSEREYVAIVWGNMTDDEGRIEGNIGRHPRNRLQNTVFENDEDEKGKPAVTHYKVIERLGYVTLVGCKLETGRTHQIRVHMKYIGHTIFNDERYGGERILKGTTFTKYKQFVDNCFKILPRQALHAKTLGFKHPVTGEQLSFDSPIPDDMQQCIEKWRNYATHVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF19</accession>
    <name>A0A5C6ZF19_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Saccharopine dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_13930</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032095">
        <property type="entry name" value="Sacchrp_dh-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005097">
        <property type="entry name" value="Sacchrp_dh_NADP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16653">
        <property type="entry name" value="Sacchrp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03435">
        <property type="entry name" value="Sacchrp_dh_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sacchrp_dh_NADP" evidence="1">
        <location>
            <begin position="4"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="Sacchrp_dh_C" evidence="2">
        <location>
            <begin position="126"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="454" mass="51626" checksum="F89C21210FD084BE" modified="2019-11-13" version="1">MRKILIIGSGKSTSYLLKYLLDKSEEEDLHIIVADKDIQNAKNLLNDHKNSQAIALDVFDRSAREKAIENADIVISMLPARYHIEVAKDCISFGKNMVTASYVSSEMADLDKAAKNKGLVFMNEIGVDPGLDHMSAMDVLDRIREKGGKIILFESFAGGLVAPESDNNLWNYKFTWNPRNVVVAGQGSAAKFIQEGTYKYIPYHRLFRRTEFLEIDGYGRFEAYANRDSLKYQSIYGLDSIKTLYRGSMRRVGYSRAWNMFVQLGLTDDSYTIDDSENMSYRDFMNAFLAYSPTDSVELKFRMALKIDQDDIVWDKLIELDIFSNKKMVALKKATPAEILQKILMDSWQLGPDDKDMLVMYHKFGYELDGKEYQIDSTMVTIGEDQTYTAMAKTVGLPVAIATLAILNEKITTPGVQIPINKEVYQPILKELQEFGIVFTEKEVPYLGYNPLNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFC3</accession>
    <name>A0A5C6ZFC3_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ATP-dependent Clp protease ATP-binding subunit ClpX</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">clpX</name>
        <name evidence="9" type="ORF">ESY86_14715</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Component of the ClpX-ClpP complex. Forms a hexameric ring that, in the presence of ATP, binds to fourteen ClpP subunits assembled into a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the ClpX chaperone family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.20.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00175">
        <property type="entry name" value="ClpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004487">
        <property type="entry name" value="Clp_protease_ATP-bd_su_ClpX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046425">
        <property type="entry name" value="ClpX_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010603">
        <property type="entry name" value="Znf_CppX_C4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038366">
        <property type="entry name" value="Znf_CppX_C4_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06689">
        <property type="entry name" value="zf-C4_ClpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00994">
        <property type="entry name" value="zf-C4_ClpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00382">
        <property type="entry name" value="clpX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51902">
        <property type="entry name" value="CLPX_ZB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6 7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="ClpX-type ZB" evidence="8">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="11"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD87920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="410" mass="45568" checksum="7F5A6F87E8EB9481" modified="2019-11-13" version="1">MAKEVLECSFCGRKKPETSLLIAGLDAHICDRCIEQAHGIVLEESKQSDNAELSSELMLKKPQQIKAFLDEYIIGQDYSKKVMSVAVYNHYKRLLQPANDDDIEIQKSNIIMVGQTGTGKTLMAKTISKMLNVPLAIVDATVLTEAGYVGEDVESILTRLLQAADYNLEKAEKGIVFIDEIDKIARKSDNPSITRDVSGEGVQQALLKLLEGTTVNVPPKGGRKHPDQKFIEVDTEHILFIAGGAFDGIDKKISKRLNLAAIGYKAAHDNDVLDMDHLLQYVIPKDLKDFGLIPEIIGRLPVLTYMDPLDAKTLRAILTEPKNAIIKQYKKLFEMDDIEFTITDGALDYIVTKAIDYQLGARGLRSLCEEILTDAMFELPSGKEKKLHVTKSYAEDKLSKTTLKKLKAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFE4</accession>
    <name>A0A5C6ZFE4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">SprT domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_12560</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="198" mass="23140" checksum="66CF3E47F22E67E8" modified="2019-11-13" version="1">MQQALEQFVPKQAITPLMTLLDHEHLTIKVKKERKSKHGDYRSLPNGFHQITINGNLNPYRFLITTVHEIAHFEAYKNYGKHIKPHGKEWKRTFQHLMLPFLSPSIFPSELLPLLARHFKNPKASSDTDIDLAYALKQFDAPNDKTYVFEVPEGTAFKLYNGRVFRKGNKRTKRYECLELKTGRLYLFNPNAEVEVLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG65</accession>
    <name>A0A5C6ZG65_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pyruvate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_09865</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016624">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transket_pyr" evidence="3">
        <location>
            <begin position="323"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="648" mass="72281" checksum="E483CE59631E7220" modified="2019-11-13" version="1">MEKNTISHKLIKTLIRIRNVEQTFLDLFSQGHLNGTVHTCIGQELSALAFAGQLKKTDFVFSNHRCHGHFIAYTNEWKPLMLELLGKKDGVCGGVGSSQHLQLYNFFSNGIQGGIMPMAAGFALGNKLKQNDAIGVVYIGDGTLGEGVVYETLNFISKKEIPVIVVCENNKYAQSTPIEYNLAGSIELRAKAFGIEFRNSSTSGETANIIDEAKASIDWVRANKKPIFHLVDTYRLKAHSKGDDDRDQSEIETNAKNDFLNILAENDPEYFKKENDKIQAEIDKFIETALTEDELSIEDYNYAEQEEKYREDVEFSPYETKKGRLVQKMNASFKKLLEDKKVIFIGEDIMDPYGGAFKVSKGLSDTFPEQVIGTSISEGLIAGVSNGLALNGFKPFAEFMFGDFTALAFDQMINHASKIYNMYNKKVTCPVVFRTPMGGGRGYGPTHSQSIEKHYIGMDAFEICASNRYLDPDIILNYLYERKHPSLLIENKVDYAKNSTISLPNGYEMLQSIEALPSILIRPTSDHAKTTIITYGGSADVVINNIENYFYEYDNLVQVLLLTKIDPIPKRLLKTVLQNASSVLFVEEGNSGGTVGDYFISYLAQNFNNLNLKAIASERISIPSAKSLEDTVLINKANIYSNLNGVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGD8</accession>
    <name>A0A5C6ZGD8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">50S ribosomal protein L24</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rplX</name>
        <name evidence="6" type="ORF">ESY86_14885</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.</text>
    </comment>
    <comment type="function">
        <text evidence="3">One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the universal ribosomal protein uL24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06089">
        <property type="entry name" value="KOW_RPL26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01326_B">
        <property type="entry name" value="Ribosomal_L24_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041988">
        <property type="entry name" value="KOW_RPL26/RPL24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003256">
        <property type="entry name" value="Ribosomal_L24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005825">
        <property type="entry name" value="Ribosomal_L24/26_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12903">
        <property type="entry name" value="PTHR12903"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17136">
        <property type="entry name" value="ribosomal_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01079">
        <property type="entry name" value="rplX_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01108">
        <property type="entry name" value="RIBOSOMAL_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 4 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="KOW" evidence="5">
        <location>
            <begin position="5"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD87952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="103" mass="11260" checksum="36394DFED8B007A9" modified="2019-11-13" version="1">MTKFKIKSGDIVKIIAGDHKGSEGKIIKILKDKNKAIVEGVNMVKKHTKPTAQSPQGGIVEKEAALHISNLSLLTAKGETTRVGYKMEGDKKVRYSKKSNEVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGG9</accession>
    <name>A0A5C6ZGG9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_13500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="70" mass="8397" checksum="D7FB36B89E51F478" modified="2019-11-13" version="1">MLVTRQDILSLKTFSTTKEAVAIDSIPNTFKKDFQLFFFGKTFFKKDNTLFAYPHDIKRWTRFMFNKYNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGJ7</accession>
    <name>A0A5C6ZGJ7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Carbohydrate kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_13200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00583">
        <property type="entry name" value="PFKB_KINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00584">
        <property type="entry name" value="PFKB_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="3">
        <location>
            <begin position="17"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="320" mass="35612" checksum="B2E23E338B8B7809" modified="2019-11-13" version="1">MKDLELKNNKRNSRTIDILCVGEVLIDFIGHQSGVGIDETRDYHRYLGGSPTNVAMNSARLGLKSLMVATVGTDGFGDYIFKRFSEVGVNTNHMLGHEDKATSVIFVSKSEGTPDFIPYRDADCCIQESQIPKAILSDTKIFHTTCFALSKKPAQSTILKKAAEAFHLGCQLSIDVNYAKKLWDSKKEALDVIKAYCKFNPLVKISEDDMERLFERHLPHNDIFEFFHAEGVEIVCLTLGSKGVKLSQKDQPIIELPAIKVEKVLDTTGAGDAFWSGFLFAFIKEKPVEECLKVALQLAALKLQNVGRLPDNITILSKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGN9</accession>
    <name>A0A5C6ZGN9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF559 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_09910</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007569">
        <property type="entry name" value="DUF559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04480">
        <property type="entry name" value="DUF559"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF559" evidence="1">
        <location>
            <begin position="12"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="124" mass="14668" checksum="84697DFCA18D0DC7" modified="2019-11-13" version="1">MRKIIKYNSYLVAFAKKLRNNMTLGEIILWREIKGKKTGVRFSRQIPIDQYIVDFYCKNLHLAIEVDGSIHFEEGQQEKDAIRQKRLEDLGVVVIRFSDLDVRNNLSWVLLNIEETIKEMKTHC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGQ6</accession>
    <name>A0A5C6ZGQ6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AAA family ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041682">
        <property type="entry name" value="AAA_14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13173">
        <property type="entry name" value="AAA_14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_14" evidence="1">
        <location>
            <begin position="31"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="396" mass="46030" checksum="BAD76AA1BE751721" modified="2019-11-13" version="1">MEQLLEKSAALVQRISTKKKRYLYHEINWNNRLIGIKGARGTGKTTLLLQKLKELRLAPTQGTYWSLDDFYFTTHSLVETAEEFFKKGGVYLFLDEVHKYENWSIHIKNLYDFYPDLKIVFTGSSIIDISREEGDLSRRMLMYTLPGLSFREYLAFNDLYDFEPISLEHMLSVDRKWTELFSSDFRPLAYFKDYLQYGYYPFSMEDKQGYATRLQQLLRLIVEYDMAELKGFDIRNAKKMLQLLNVVAANVPFQPNITNIASKSDIHRNSVVTYLHFLEQAKLIRLLYASGISLATLQKPEKVYLDNPNLAFSFSTADPNKGNLRETYFISQVAVRHKVSYPNQGDFLVDDMFTFEVGGKDKTNKQISGIKNAFVVADDAAYPITKLPLWLFGFLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGV2</accession>
    <name>A0A5C6ZGV2_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 7" type="primary">rplU</name>
        <name evidence="7" type="ORF">ESY86_08210</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">This protein binds to 23S rRNA in the presence of protein L20.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit. Contacts protein L20.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the bacterial ribosomal protein bL21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01363">
        <property type="entry name" value="Ribosomal_L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036164">
        <property type="entry name" value="L21-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028909">
        <property type="entry name" value="L21p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001787">
        <property type="entry name" value="Ribosomal_L21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018258">
        <property type="entry name" value="Ribosomal_L21_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21349">
        <property type="entry name" value="PTHR21349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00829">
        <property type="entry name" value="Ribosomal_L21p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141091">
        <property type="entry name" value="SSF141091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00061">
        <property type="entry name" value="L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01169">
        <property type="entry name" value="RIBOSOMAL_L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 5" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="108"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="108"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="125"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD89365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="254" mass="27918" checksum="FBC09FF6D85756E2" modified="2019-11-13" version="1">MYAIVEIAGQQFKVEKDQKVFVNRLGSDEGSKIDFDSVLLIGDGDNITLGAPAIDGALISAKVLRHLKGDKVIVFKKKRRKGYRVKNGHRQALSEIVIESIVGSGAKKAEKTEKAKPAKTEQAAPVKDTKTSTSPAAKTTPKKETKKEADISENLVTRAEHRADEAQIEINIDKVLHNVGTALKADADDLKMINGIGPAYEERLNELGIYTFEQISKLKAADREELSAVDGITRDKIESEEWVKQAKALLKDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGV3</accession>
    <name>A0A5C6ZGV3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022912716" evidence="1">
        <location>
            <begin position="20"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="170" mass="19241" checksum="79FD1DB452A4EAF2" modified="2019-11-13" version="1">MKTIIMGLIVSLITTAVLAQHENVMVTSFETSNHKVYEKSAANSNYINAALEKTVAKRIATLEDIVANYDIKQESIYSPNKKTTYTVDFKQNSDHIKAIYDQEGLIIKTEEAYNNVRMPYSISGKLAQNYPGWSFENVKCLITYSNGDKRIAYHVELAKGRDSKLVELIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGX4</accession>
    <name>A0A5C6ZGX4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">T9SS type B sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_08355</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026341">
        <property type="entry name" value="Bac_Flav_CTERM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="SSF49265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04131">
        <property type="entry name" value="Bac_Flav_CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022739233" evidence="1">
        <location>
            <begin position="20"/>
            <end position="1531"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="2">
        <location>
            <begin position="200"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="2">
        <location>
            <begin position="469"/>
            <end position="561"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1531" mass="163948" checksum="2A05AE62620599DD" modified="2019-11-13" version="1">MKKITLVLVLLLAVSGAYSQIVNEPANWPNTAWLVEGTGLDDADVFEADPTLTANFAYDDDDAGSGTDNEVSAASPIIDLSAAASAGETWMTVSGNYVHRFLSSDFLIFQYWDADAETWNDWGSPFVTTTTAAPFDNFCSVAGVPYTTEVLNIFSFTATQLSGFKYRIYYNDDLDGSGWNYGFCFESPTLTSETPPTCPVVSGISVSNIGATTADIAWAAGGSETQWEVAVQPAGTGEPAGSGEATSNNPYTATGLTAVTDYEVYVRANCDADGFSNWQGPVNFLTACDVFVPFYSEDFATIIPNCWDEANNGTAATGPLELGAGSWGADGYLNNGFSGAYKINLWVTGKSDWILSPQFDLTGGPYQVDFDFAIMEWGSSSAAGTLGSDDIVQLLISADNGATWTVLITYDKDSVIPASGIQVVYDLSAYAGQIVQFGILGSEGTVNDEEDNDVFVDNFRVRDIPSCQEPSDLAVANITETTADLSWTANAGETSWEIINQDAGGAAPTESDSGIATSDNPYQATGLVEGGNYEFYVRAVCGTNDVSLWVGPSSYRISGPGEVCEDPIIVTTPLPYITSDDTANYLDDYNGSAGENCGSTFGYLNGDDVVYAYTPDVDTSVDIELSELTDNYAGVFVYTDCADIGTNCQAGALNSFSSDDLAIDDFIVTGGTTYYIVISTWASPQSTGYTLTIRENTCINPTAGFQVVNDCENGEQFLVDVNVTSFGDAESLTISTDFNATTVEVTELGTYQVGPFPFLTDVTISINNDQDSNCFLNETFQLLACPPDNDNPCDAIEVAVNTDSSCDLTTSGSLIEATPSGVPNGSCEGNPDDDVWFQFVAENEVQVISILNNTGTFNIDHGLYEGSCEGLVELACTNGDASVSPQLVVGNTYYLRVFSGGSNPETNTFDICIKKAPSNLICENAVNFCAEDGGALISSNIIGVPSIGEIACLSSTPNPTWNIIQIGSDGLIEIQIDQIDDQGEGLDVDFALWGPFDSLANACGNLDTGCPDPDDCPNNNGFFGNPDFYPFGNIIDCSWSAETTENLTIDNALSGEIYVLLVTNFSGDPGTISIAQTNGGTADGTITAEIEVELGADQEFCGFPDYVLNAESPFADSYVWYADGFVIEGETEATLTVTETNIYTVIAFDEQCGSQAEDSISITFGQEAIANPVEDIVTCDDATGDEVENFDLEMQTATILGEQDPAVFNVTYYVTLQDAQTSTNPLTSPYNNVSNPQTIFVRVEDTNANFCFATTSFDLVISGPTPTAASVDIEACDEAEGNASFDLAAHDVNILDGQSQEEFTVSYYENEADAEAGTNAIDDSTLYGSNSQTLYARVESNISFDCYSTTAFDLIVKPLPNTTFAEDFDYEVCPDATVPIMINATAGNYEASAVTIQWYRDGGLITGETNLSLAVLEAGTYEIQVSFNDASQCSSSAAIEVIELENCVIPEGISPNGDGKNDTFDLSSYDVSKLEIFNRNGTRVYQKRNYTNEWFGQSDDGEDLPVGTYFYTMEYQNGKQRAAWVYIQRLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH23</accession>
    <name>A0A5C6ZH23_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Winged helix-turn-helix transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_11790</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00033">
        <property type="entry name" value="HTHASNC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="4">
        <location>
            <begin position="6"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD88643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="159" mass="18174" checksum="485589C3623C527A" modified="2019-11-13" version="1">MAKFKLDEVDHQILDMLIDNTRIPFTDIAKKLVISAGTVHVRVKKMEEAGIIQGSTLTLDYKKLGYSFIAYVGIFLNNTSQTKFVLERIAEIPNVTVAHITTGKFNVFCKVRAKDTSHAKDIIFKLDDIEGIYRTETMISMEESLNDKKRLMHTIFNEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH30</accession>
    <name>A0A5C6ZH30_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">S8 family serine peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_12200</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017317">
        <property type="entry name" value="Pept_S8_subtilisin_bacteroid-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037903">
        <property type="entry name" value="Subtilisin_rel_GFO_2223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Peptidase_S8" evidence="5">
        <location>
            <begin position="166"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="domain" description="Por_Secre_tail" evidence="6">
        <location>
            <begin position="462"/>
            <end position="532"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF18962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD88500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="534" mass="57997" checksum="61F161973A9FF749" modified="2019-11-13" version="1">MKRSVLIIFVLCCHNLIAQEDAWVYLTDKPNVEASINNPISILTQQAIDRKTDQGIAIDVRDVPVNEAYITQLKNAEGITVYAKSKWFNSVYVRGSETDISALMTDFDFVATIDFADAELNALSRSTISYNKFEIEETLVNFNYGNTQNQVEMIGVDDLHLSDFTGEGIIVAVMDSGFPNVNTMGAFQRLRDNADLLGGYDFVDRTENVYDFNQNDHGTKVLSDMAGFIQDQFVGTAPDASYYVFRTEDIFSETPVEEAYWVEAAERADSLGVQVINTSLGYKTYDNPNYSHSDADLNGSTTFITRGANVANEKGILVITSAGNSGQAGVGAPADATGVLSVAAVDAEGNYVAFSSQGSAFQATQKPDVAAQGFAAAVINLNNATVYNNGTSFSSPILAGGIASLLQALPNTSHEDIKALVRMSASQYENPDFLLGYGIPDLSQALAIGLSVENEAFYGLKVFPNPVGNTLHITQQSRSETTKFRLLDVLGKTILKQNSNTLETQLDLSSLNAGIYVLQIQSEKASKTFKIIKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH41</accession>
    <name>A0A5C6ZH41_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_09655</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="65" mass="7886" checksum="3B2849E04D979727" modified="2019-11-13" version="1">MYYLNFSDLSEEAQERLLAISKKDVERKFGDDMRKYVDKNFANFDVLIEEEAQRNLYSYSFKFLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH98</accession>
    <name>A0A5C6ZH98_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alkaline phosphatase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_12535</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004035">
        <property type="term" value="F:alkaline phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16016">
        <property type="entry name" value="AP-SPAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026263">
        <property type="entry name" value="Alkaline_phosphatase_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002591">
        <property type="entry name" value="Phosphodiest/P_Trfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01663">
        <property type="entry name" value="Phosphodiest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF031924">
        <property type="entry name" value="Pi-irrepressible_AP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022731314" evidence="4">
        <location>
            <begin position="20"/>
            <end position="554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="170"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphothreonine intermediate" evidence="2">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR031924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR031924-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR031924-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD88560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="554" mass="62101" checksum="1824E15D06E23D9D" modified="2019-11-13" version="1">MKYLIKLMLVLLVVASSKAQTLNESNASTTKIAQDSRPKLVVGIVVDQMRYDYLTRFYDRYGDGGFKRMMTEGFNCKNNHFNYVPTYTGPGHASVYTGTTPKYHGIIGNDFYDRERKEMVYCAGDDSVQSVGTQDDAGKMSPHRMKTTSFTDENRLFTQMKGKTIGIALKDRGAILPAGHTANAAYWFHGRDEGAWITSTFYRNDLPKWVSDFNDSNAAEYYFKVWDTFYDMSTYTQSGLDENDFEGGFRGQEKATFPYDLSKLSKDNREFDILKATPYGNSLTTDFAMAAIKGEQLGKDDVTDVLTLSYSSTDYVGHNFGVNSKEIEDTYIRLDLDLERFFKFLDAEVGKGEYTVFLTSDHGAIEVPSYLASVKIPAGYLDNNLRKEQFNTFLQNTYGTTEIMENYSNSQIFLDRKKVMDMGLDLQDVQQAIANEQLTYEHMAKVYTATTMSTNDFTSGVEELLQNGFNQKRSGDVILVNDIGYISYGKTGSTHGSALNYDTHVPLLFFGKGIKQGATFDKTVISDIAPTMSALLGISFPNGSTGQPLGYVID</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHA1</accession>
    <name>A0A5C6ZHA1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_09935</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="12"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="76" mass="8190" checksum="D466BA7EA22886FA" modified="2019-11-13" version="1">MQVKFYFTTYFSTSTSTSTSSSSSSSSSSSSSSSSSSPVSRLPSSVSLFFPLFSALIREICGISQVSLYSSRRSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHC8</accession>
    <name>A0A5C6ZHC8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Class I SAM-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_10110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="254" mass="29194" checksum="19CB3103FDD4D2A6" modified="2019-11-13" version="1">MDKAYETHYHDLERSHFWFKARRNYILQLLKDVPKTANILDIGCSSGLLLTDLKNQGFNPNNLYGIDISKKAIANCKQNGLQNCAVMSADTIKLDLKFDVLIASDCLEHLQNDEKAVRNWRHLLKADGKLYIFVPAFQALWSQHDVINMHYRRYTEKQLLNLVTNNGFEQLKSGYWNALLFIPIYIARKLGKLKATKNETSKSNSSGDLETLPSLNPIFLGLLNFENRILKYVRFPFGVSTYCILAKAEKDSTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHF4</accession>
    <name>A0A5C6ZHF4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lipocalin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_11645</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024311">
        <property type="entry name" value="Lipocalin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13648">
        <property type="entry name" value="Lipocalin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022875350" evidence="1">
        <location>
            <begin position="20"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="Lipocalin-like" evidence="2">
        <location>
            <begin position="36"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="140" mass="15569" checksum="5DF3BF5552A4AF41" modified="2019-11-13" version="1">MKKLILLLTAVTLTFTSCSSDDDNPPIQEVEEDAFVGVWSLSKALLNDNELPIDDCDVQSNFTIKSNGTFVESSYTTTAAGTCESDFADAGTWENLGNNTYKLKYDADEDGDTYQEDVAVNTESFSIFYDDPYIYVFTKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHK2</accession>
    <name>A0A5C6ZHK2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2834 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021362">
        <property type="entry name" value="DUF2834"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11196">
        <property type="entry name" value="DEP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="114" mass="13340" checksum="3E115FE306DB4C90" modified="2019-11-13" version="1">MKFKHLYLLLAIIGLIYTWYFNIQFYQTATDTSILNFIDLTKTTIPAQSIVADITVVGITFLVWMVHESLKLKIKYWWLIIPLSFLVALAFSFPLFLYMRANRLEKIGTLEARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHL9</accession>
    <name>A0A5C6ZHL9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA small subunit methyltransferase H</fullName>
            <ecNumber evidence="6">2.1.1.199</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">16S rRNA m(4)C1402 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">rRNA (cytosine-N(4)-)-methyltransferase RsmH</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 7" type="primary">rsmH</name>
        <name evidence="7" type="ORF">ESY86_09355</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>cytidine(1402) in 16S rRNA + S-adenosyl-L-methionine = H(+) + N(4)-methylcytidine(1402) in 16S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42928"/>
            <dbReference type="Rhea" id="RHEA-COMP:10286"/>
            <dbReference type="Rhea" id="RHEA-COMP:10287"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74506"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.199"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the methyltransferase superfamily. RsmH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.199" evidence="6"/>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071424">
        <property type="term" value="F:rRNA (cytosine-N4-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01007">
        <property type="entry name" value="16SrRNA_methyltr_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002903">
        <property type="entry name" value="RsmH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023397">
        <property type="entry name" value="SAM-dep_MeTrfase_MraW_recog"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11265">
        <property type="entry name" value="PTHR11265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01795">
        <property type="entry name" value="Methyltransf_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004486">
        <property type="entry name" value="MraW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81799">
        <property type="entry name" value="SSF81799"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00006">
        <property type="entry name" value="TIGR00006"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6 7" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="6">
        <location>
            <begin position="32"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD89241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="298" mass="33643" checksum="AE82EA1A3999DCEA" modified="2019-11-13" version="1">MNYHNPVLLEETVDGLTIKPDGVYVDVTFGGGGHSKEILKRLGSKGKLYAFDQDKDALSNTIDDERFTLINENFRFVKRFLRFYGVKEVHGVLADFGVSSHQFDVAARGFSTRFEADLDMRMNQADKISAFNVVNHYSEERLKDVLAQYGELRQAPAMASAIVAERKNGELKTSEQFKAALSSFLNHQKENKVLAQIYQAIRIEVNQEIEALKEFLQQTPDILVKGGRLSMISYHSLEDRLVKRFIRNGLFEGEPERDVFGNFEVPLKKVGGLIVPSKAEIAANSRARSAKLRIAKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHR0</accession>
    <name>A0A5C6ZHR0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF4412 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_11355</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025524">
        <property type="entry name" value="DUF4412"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14371">
        <property type="entry name" value="DUF4412"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022843317" evidence="2">
        <location>
            <begin position="23"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4412" evidence="3">
        <location>
            <begin position="98"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="291" mass="32592" checksum="AE53D50D539A49F3" modified="2019-11-13" version="1">MKSRFSVVIIMIAFLAGGSANAQFFKKLKKKAEQAAERTILNRADEEVSKGTDKTIDKAIEGDANKQKDSSKSRDAMNKRAMSVYGGDMNDIPETYKFQYIMDMKMTTNKDDMRINYYIQPNASYFGTAVPSGQDNNSVVVYDLAKEAMVTFIDANGQKMAMKVNMPLDEKMQESIKNGQLGQDGSAEDVEVTPLASKTILGYHCKGYQIKNEDGSTKVYITNEAPVSFVGMFANMKDMQKNMGSSAIPFDENSMMLEMEYNSSTRKKERMHMICTAIKEQSFSISKADYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIB8</accession>
    <name>A0A5C6ZIB8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tryptophan--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">trpS</name>
        <name evidence="9" type="ORF">ESY86_07655</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.2" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004830">
        <property type="term" value="F:tryptophan-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006436">
        <property type="term" value="P:tryptophanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00806">
        <property type="entry name" value="TrpRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002306">
        <property type="entry name" value="Trp-tRNA-ligase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01039">
        <property type="entry name" value="TRNASYNTHTRP"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00233">
        <property type="entry name" value="trpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD89650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="322" mass="36124" checksum="A15938847E9FC996" modified="2019-11-13" version="1">MARILTGIQSTGTPHLGNILGAILPAIEISKTDKNDSFLFIADLHSLTQIKDADTLKQNTYSTAATWLAFGLDIEKTVFYRQSDVPQTTELSWYLSCFFPFQRLTLAHSFKDKSDRLEDVNAGLFGYPMLMAADILLYDAEIIPVGKDQMQHIEITRDVASRFHAKMGDTFVIPEGKIQESTMLIPGTDGAKMSKSKGNYINVFLPEKQLRKQIMSIETDSTPLEAAKNWSTCNCFAIYSLLASEAEVGSMKANYENGNYGYGHAKQALYELILTKFETPRERYTHFMNNHHEIDEALAIGAEKAKLVANAVLERVRKKLGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIN1</accession>
    <name>A0A5C6ZIN1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sulfite exporter TauE/SafE family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_11275</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039447">
        <property type="entry name" value="UreH-like_TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13386">
        <property type="entry name" value="DsbD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="DsbD_2" evidence="2">
        <location>
            <begin position="4"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="234" mass="25642" checksum="0424756858E5F795" modified="2019-11-13" version="1">MLWTAFIFGLLGSFHCVGMCGPIAFMLPVDRSNSTRKVFQIFTYHFGRLLAYSLIGLAFGLVGKGLYLFGIQQYLSIFIGILMIVVVLTPVQTFNKYNFSKPLYRLIGKVKSSMGKAFKKKSADTFLTIGFLNGFLPCGLVYMAVFASLAMQNAVYGSLYMTLFGLGTIPLMTTAIYIGKFLNVSVKKRIQKAIPVFVVVIAVLFIIRGLGLGIPYLSPAPMVDMASSAIDCSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIQ1</accession>
    <name>A0A5C6ZIQ1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_12580</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="72" mass="8428" checksum="C51BBBC48D0BCBD0" modified="2019-11-13" version="1">MDIQASKIELAKIILNSENDSFIKRLKEFISNEDADFWNRLNPSERSEIQEGIEQLNLGKRTKFNEVLENLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIT7</accession>
    <name>A0A5C6ZIT7_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ATP synthase gamma chain</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ATP synthase F1 sector gamma subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">F-ATPase gamma subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 10" type="primary">atpG</name>
        <name evidence="10" type="ORF">ESY86_07740</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the ATPase gamma chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042777">
        <property type="term" value="P:proton motive force-driven plasma membrane ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12151">
        <property type="entry name" value="F1-ATPase_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00815">
        <property type="entry name" value="ATP_synth_gamma_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035968">
        <property type="entry name" value="ATP_synth_F1_ATPase_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000131">
        <property type="entry name" value="ATP_synth_F1_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023632">
        <property type="entry name" value="ATP_synth_F1_gsu_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11693">
        <property type="entry name" value="PTHR11693"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00231">
        <property type="entry name" value="ATP-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00126">
        <property type="entry name" value="ATPASEGAMMA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52943">
        <property type="entry name" value="SSF52943"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01146">
        <property type="entry name" value="ATPsyn_F1gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00153">
        <property type="entry name" value="ATPASE_GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0139">CF(1)</keyword>
    <keyword evidence="4 9" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="5 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD89666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="286" mass="31736" checksum="FC29B85DA9E53E5F" modified="2019-11-13" version="1">MANLKEIRNRISSVSSTMQITSAMKMVSAAKLKKAQDAITAMRPYSDKLTELLQNLSATLKEDAGSELAEQREVNKVLLVAITSNRGLCGAFNSNIIKAVSKRATTAYANQEVSYVAIGKKAYDAFKKTKQVIANKSEVYDDLTFDHVAEIAEMLMEKFVSGEYDRVEIIYNSFKNAATQELMIEQFLPIVPLEGDANLSTDYIFEPSKLEIVEELIPKSLKTQLYKAIRDSFASEHGARMTAMHKATDNATELRDQLKLTYNKARQASITNEILEIVGGADALSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIT8</accession>
    <name>A0A5C6ZIT8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">OmpH family outer membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_08045</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Skp family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.910.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005632">
        <property type="entry name" value="Chaperone_Skp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024930">
        <property type="entry name" value="Skp_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35089">
        <property type="entry name" value="PTHR35089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03938">
        <property type="entry name" value="OmpH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00935">
        <property type="entry name" value="OmpH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111384">
        <property type="entry name" value="SSF111384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="79"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="172" mass="19650" checksum="277D22ADB7ABDC34" modified="2019-11-13" version="1">MRKLVGLFSVALILASCQEQQKIAFVNNGEVINAYTEKIEIEAKYEKMDADFQKRTDSIGQAFQTEAQDFQTKAANMSQQEQQEQYQVLGQKQQRLQQQIQQEQQQLGQKFNVEIDSAMSHVKQFVTDYGKENGYTFILGKNEAGSVMYGEEAKDISKEIIEALNADYKKAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIY1</accession>
    <name>A0A5C6ZIY1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10175</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0675">Receptor</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022799566" evidence="1">
        <location>
            <begin position="23"/>
            <end position="573"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="573" mass="64695" checksum="8025DCB755320DBB" modified="2019-11-13" version="1">MPNRLQHKLLALILVVSATTFAQEREKDSIDTETVNVVKAYTPTISDAFKIKETPNLNDSTNLKKKDIKYNIFSIPVASTFTPAKGKAAGVNKEKSVKLYDNYASVGLGTYATILGEVYLNHQLSRNERVGGYFSHHSSQGDIDGINYDNNFRETELGANYTQQQRDFTWKLEGGYELQRYNWYGLPDQTLPFFDVGHSFYNANIGGNIDFEDGIFNKATVLFRRFGDSRNSAENRFLVTSEFDVPVNDQTITTEVNIDYLSGGFDHTYFSETELNYGNFQLGVAPSYQFIQDDLTLNLGVRLVYFNDTEASQSKLHFYPNVTASYRLVDELLIGFGGIEGGLQQNSYFGFADENRFVAPTLFVQPTDQSYDVSAGIKGKLSNSMSYIVTGHYLSENNRALFKANPDLLTERKNYQFGNSFGVVYDDLKTFSFEGELNVDLNRNFKLGAKAAFFAYSTDSEAEAWNLPDLKASVFMDYQIDAHWFAGANLFFVGERKDQISEGRNPQLSLNQPQTVTLDSYFDANVHAGYKISDRLSAFVKGNNLVGTNYQRWLNYPVQGIQFLAGATYQFDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIY7</accession>
    <name>A0A5C6ZIY7_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Aminopeptidase N</fullName>
            <ecNumber evidence="3">3.4.11.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">ESY86_06580</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal amino acid, Xaa-|-Yaa- from a peptide, amide or arylamide. Xaa is preferably Ala, but may be most amino acids including Pro (slow action). When a terminal hydrophobic residue is followed by a prolyl residue, the two may be released as an intact Xaa-Pro dipeptide.</text>
            <dbReference type="EC" id="3.4.11.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.2" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09599">
        <property type="entry name" value="M1_LTA4H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038502">
        <property type="entry name" value="M1_LTA-4_hydro/amino_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034015">
        <property type="entry name" value="M1_LTA4H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015211">
        <property type="entry name" value="Peptidase_M1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45726">
        <property type="entry name" value="PTHR45726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09127">
        <property type="entry name" value="Leuk-A4-hydro_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01263">
        <property type="entry name" value="Leuk-A4-hydro_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="SSF63737"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Leuk-A4-hydro_C" evidence="12">
        <location>
            <begin position="474"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="311"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10">
        <location>
            <position position="398"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="310"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="314"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="333"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR634015-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR634015-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TXD89863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="621" mass="70717" checksum="895AC22B25C9CEA5" modified="2019-11-13" version="1">MKSQISLLAILLLSLSCQTEQKPEKTVTKYVEEPHSYAQPNDAVITHLDLDIKVDFESKTIAGVATYDIDTNDASEIILDSKYLDIEKVEANGNATTFSMGDFNEDLGQALKIAITEDTNKISVFYKTTSQTEAVQWLAPQQTLDKEQPFLFTQGQAILTRSWIPIQDSPQIRITYDATVKVPNNLMAVMSAENPKQKTEDGVYQFKMKQPIPPYLIALAVGDLEYKPISDRTGVYAEKSMVDKAQEEFSDMEKMVAAAEKLYGDYAWEQFDVIVLPPSFPFGGMENPRLTFATPTVIAGDKSLTSLVAHELAHSWSGNLVTNATWDDFWLNEGFTVYFENRIMEALYGKDRANMIALIGRQDLADEIENFKDAPEMTRLKLDLEGKNPDDGMNSIAYDKGFLFLRTLEEKVGRDKLDSFLKAYFSKNAFKTMTTEKFVDYLNLNLLEPNNIDFNVEEWIYEPGIPDNQVVIVSDKFEQTETVLNTFLDSKSIDASKTKDWTTDEWVHFIRNFPESISTEDLQRLDNAFDFTNASNSHIAMVWYEQAINHDYHGNDVDAKIEDFLTHVGRRWYVATLYKAFERNDKTEAALAIYKKARPNYHSVTANTIDDLLGFEAEEFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJD1</accession>
    <name>A0A5C6ZJD1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_08555</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="SSF50022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="141" mass="15711" checksum="613FA9E81FEC5F28" modified="2019-11-13" version="1">MKKLMLLLSFLILNSCSDDNRINNCNYLQNLGINRTLNLNLPSNGQLLFPLSPVYIPNEGNAGIYVIRTVSGQYRAWDAADPNHPQENCSFMERDGIVVTCGCVDENKYDLVTGQSRNEPLPCGLKEYRVTVSGNNLLVSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJD4</accession>
    <name>A0A5C6ZJD4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF4254 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_07825</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025350">
        <property type="entry name" value="DUF4254"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14063">
        <property type="entry name" value="DUF4254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="202" mass="23665" checksum="CD883C43BE1FAF50" modified="2019-11-13" version="1">MFSDKANTIFQDVILTYHKLNNVGQPFTNLYDKDKQLIEHLLYRKSWIDTVQWHYEDIIRDPQIDPDAALKLKRQIDASNQDRTDMVEYIDSYFLEKYKDVTPKPDATINTESPAWGIDRLSILALKIYHMNDEAIREDASDAHRTACKTKLDILLEQRKDLSTAIDTLLEDIGKGDKYMKVYKQMKMYNDDELNPVLRSGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJI7</accession>
    <name>A0A5C6ZJI7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_09240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022831650" evidence="1">
        <location>
            <begin position="20"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="433" mass="47597" checksum="9F0C78191455FC0C" modified="2019-11-13" version="1">MIRKLVIVLIACYAVQTHAQEGTASPYSFYGIGSLKFKGTVENRSMGGLSIYTDSIHVNLKNPAAYVGPNLKIWNNEARPVKFSIAGSQSSINLKANSGEAKVSTTTFDYMALSLPLGDFGVGFGLVPYTSVGYKLEDFDDSALRNRYKGEGGVNRAFLGLGYRITDKLSAGIDVNYNFGNIQNSAIEFVYDGEGRLVQYQTRENNRSDLSGINFNLGLTYKTMINEKLEMQAGLTYSPKSNITSKNQRAFSTISVNTAGQEFLVNGFDADLASLGLEETDLTLPSRFSIGAGIGAPRNWFAGLEYSRQNTSEFANPIVSINNANFVNASSVALGGFFVPDYNSFSSYWKRVTYRAGVHYENTGLEINEQSINEFGISFGVGLPVGGIFSNTNLGAEIGRRGTKDLNLIQENFFNLQISLSLNDRWFEKRKYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJK4</accession>
    <name>A0A5C6ZJK4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Universal stress protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_07000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal stress protein A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="2">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="281" mass="32805" checksum="5A8732387E81DA3A" modified="2019-11-13" version="1">MKTILLPTDFSENSWNAIVYALDFFKQSTCTFYLLHVNSLNYLDANDLPYDDSKDFVENTFTKPSKKKLRTLLKRILTEFPDHKNHHFFTLTDYNFFVESVRNHVDEKKIDMIVMGTKGATGLQKVIIGTNAADVIKKVKCTTLVVPEHATFSDLDEIVFPTDYYLTYGVDLLKPVYTILQNHKASLQVLHITNQPEALNMSQQDNKDLLMDYFSNFETKFHNLTHRKVEDAIEFFVKSRDIKMVAMVAKNLNYFQRVLFHSKVEEITYHTRVPFLVLHDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJZ7</accession>
    <name>A0A5C6ZJZ7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NAD-dependent succinate-semialdehyde dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_10840</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004030">
        <property type="term" value="F:aldehyde dehydrogenase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07100">
        <property type="entry name" value="ALDH_SSADH1_GabD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044148">
        <property type="entry name" value="ALDH_GabD1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="2">
        <location>
            <begin position="3"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="460" mass="50533" checksum="EB97CBAA06188013" modified="2019-11-13" version="1">MSDKTFDTINPFTEEKIKSYTYMTEKEAVSAVEKCHEAFLKWKHKSLDERGKVVAAIGKELNKNKEALAKLMTNEMGKLIKQGHQEVELCAGICEYTATEGKKSLQDEERIMANGGKGVIQYAPIGVIYGIQPWNFPTYQVIRYAVVNLMAGNGVLLKHANNVTGSALMLKDIFESAGLPKDLFTVLIMDHDTSDKVIEHELVRGVTLTGSSGAGKVIAKKAAEFLKKTVLELGSNDAYLVFEDADIELAAKTCVQGRIYNNGETCVAAKRFVVAEKVYDQFKEAFVKGMKAINHGDPTKDDSKMGPMARKDLREILHDQVEKSVNKGAKILCGGEMPKEKGYFYPSTVLENVKPGQPAYDDELFGPVASLIKAKDNDDAMRIANDSRFGLGGGIFSKDEEKAVEFAKSHFDTGIVNINSFGLAHPSMPFGGVKNSGYGREHGGFGIKEFVNVKSIMRSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK24</accession>
    <name>A0A5C6ZK24_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Iron-containing alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_03385</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039697">
        <property type="entry name" value="Alcohol_dehydrogenase_Fe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496">
        <property type="entry name" value="PTHR11496"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00465">
        <property type="entry name" value="Fe-ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-ADH" evidence="2">
        <location>
            <begin position="4"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="353" mass="39290" checksum="A4C1B3CD42D32C4A" modified="2019-11-13" version="1">MVSRVVFGRGSFDQLQDILAPKRLNVKAPFIFLVDDVFKGDSWITSRIPLAYKDQILYISANEEPTTAQVDELVDQIILNHNDGPSGIIGIGGGSLMDLAKAVSIMLNNKGGAKDYQGWDLVKSAAVYHVGIPTISGTGAEVSRTTVLTGPDKKLGINSDYTPFDQVILDPELTRDVPRDQWFYTGMDCYIHCIESLNGTYLNAFSESYGEKAYELCKNIFVDDKLSDEEAQDQLMMASWHGGMSIAYSQVGVAHAMSYGLSYLLGTKHGIGNCIVFDHLEDYYPEGVQLFKKMKQKHNIVLPKGICADLSDEQFDVMIKVALSLEPLWENAIGKNWKNVITYDKLKALYQKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK55</accession>
    <name>A0A5C6ZK55_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Iron ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_03085</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000522">
        <property type="entry name" value="ABC_transptr_permease_BtuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30472">
        <property type="entry name" value="PTHR30472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01032">
        <property type="entry name" value="FecCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="61"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="90"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="124"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="152"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="204"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="245"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="285"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="312"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD90366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="340" mass="36562" checksum="6F4AB6FBE057B25C" modified="2019-11-13" version="1">MKTKTSNSFLLLSAVLLLCFLMNISLGSVSIPLEEVFKSIFGNSENESWQYIIQDYRLPKAFTAILVGSGLGVSGLLMQTLFRNPLAGPYVLGISSGASLGVAMVILGSGLFGGIFGTLLMSKWSLVIAASLGSFIVLLAVMLVSSKVRDTMAILIIGLMFGSITTAIVSVLSYFSSAEELQRYIFWGFGSLGNLSWHELLIFFGIYVVGMFISIGSIKALNTFLLGENYAKSLGLNIKKSRMLIIIATSLLAGTITAFAGPIAFIGLAIPHLTRQIFKSANHKILLPAVLLFGAIVMLVCDSIAQLPTSDYTLPINAITSLIGAPVVVWLLVRQRKMVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK58</accession>
    <name>A0A5C6ZK58_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_05620</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007492">
        <property type="entry name" value="LytTR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04397">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00850">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50930">
        <property type="entry name" value="HTH_LYTTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="8"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="HTH LytTR-type" evidence="3">
        <location>
            <begin position="139"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD90219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="238" mass="27712" checksum="1C5E5A1EF854381B" modified="2019-11-13" version="1">MSKDQTISCLIVDDEDIAREIIETHLSKIDNIQVVASCSNAIEAFEQISNQQIDLIFLDINMPGISGISFAKSINTHIKIIFTTAYRDYAVEGFELKAVDYLLKPFSFERLKKALDTYFEIYGNTPETERSSDEKSDFIFVRSDRKMIKIDYDSIIFIESYSDYLKMHLDQNTIVTRETITTIEAKLPIQKFLRIHRSYIIAVNHIESFKNERITINNKILPISRTYKKKVLQFLENI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKJ5</accession>
    <name>A0A5C6ZKJ5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycosyltransferase family 4 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_07855</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13579">
        <property type="entry name" value="Glyco_trans_4_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="3">
        <location>
            <begin position="17"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="2">
        <location>
            <begin position="240"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="401" mass="46040" checksum="35772A08975C5CBB" modified="2019-11-13" version="1">MKEIAIITSYFPPEPGAASNRIHHLAEGLQHLDYKVSVITPLPNYPTGRIFEGYRSRFKQVSEENGVTIHRLWIFASNSKNKFFRLFAMLSYSFSLIWFFLWNKLPKTVIVQSPPLLVAFTCMLFLRSKKRKLILNVSDLWPIAGLELGAFKKNFSYRILERIEKFNYANADLAMGQSMEILEHIGSICPKKALFLYRNFPNFNLPELPKQHSETRKLSIVYAGLLGIAQGIYSMCEQLNFEGIELHIYGSGAEQSKLEAFIADHAYLPIVYHGQVSRQELHRVLQAYDVTVIPLLNRIYGSVPSKIFEYARLGLPMLYFGGGEGETLIKKHELGWVAKAGNYAHLNTVISTIQKEQITGQMRTEIQETARIHFDFDKQLLELERVILEKSIKNQESRTET</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKT8</accession>
    <name>A0A5C6ZKT8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Gliding motility protein GldL</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">gldL</name>
        <name evidence="2" type="ORF">ESY86_05670</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019852">
        <property type="entry name" value="Motility-assoc_prot_GldL"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03513">
        <property type="entry name" value="GldL_gliding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="212" mass="22881" checksum="08C2A5D75A6F5C55" modified="2019-11-13" version="1">MAQKGKLSQMNMVYGLGAAIVILGALFKIQHWPYGSLILTIGMVVEAIVFTISAFERQQSDLDWSLVYPELAGGANFGKKQIKGEDPKDAEGLLSKKLDSLLKEAKIDGELMASLGTSIKNFEGAAKGISPTVDAMTAQKKYSEEMSLAAAQMESLNSLYRVQMESANRQATINEESVESATKLKEQMKSLASNLSSLNGVYGGMLSAMNKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKU8</accession>
    <name>A0A5C6ZKU8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">GLPGLI family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_07575</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005901">
        <property type="entry name" value="GLPGLI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09697">
        <property type="entry name" value="Porph_ging"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01200">
        <property type="entry name" value="GLPGLI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="234" mass="27199" checksum="E15FBDC0EC1552C7" modified="2019-11-13" version="1">MIRNSIFILILLHFSNSYSQQIEGKIIYKSKIEKVTDKENSALNALNRVIENNDYADFELSFKNNETLFKIAPNLEQGDNELNLSKILLGARYIFYSNNQKHEMFYQLEAYGAFFLISYESIKWELTKDSKKIGDYNCYKATTTKKVRNSRGVFEHKVTAWYTPEIPISIGPKGYHGLPGLVLELREKNKVYVAKNINLNNLEENITIPTKGRKISQYDFDNIGIEMDEARQRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKV0</accession>
    <name>A0A5C6ZKV0_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pyrroline-5-carboxylate reductase</fullName>
            <shortName evidence="2">P5C reductase</shortName>
            <shortName evidence="2">P5CR</shortName>
            <ecNumber evidence="2">1.5.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">PCA reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 5" type="primary">proC</name>
        <name evidence="5" type="ORF">ESY86_02245</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>L-proline + NAD(+) = 1-pyrroline-5-carboxylate + 2 H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:14105"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15893"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="EC" id="1.5.1.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>L-proline + NADP(+) = 1-pyrroline-5-carboxylate + 2 H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:14109"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15893"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="EC" id="1.5.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-proline biosynthesis; L-proline from L-glutamate 5-semialdehyde: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the pyrroline-5-carboxylate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.2" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00361"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004735">
        <property type="term" value="F:pyrroline-5-carboxylate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01925">
        <property type="entry name" value="P5C_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028939">
        <property type="entry name" value="P5C_Rdtase_cat_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029036">
        <property type="entry name" value="P5CR_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000304">
        <property type="entry name" value="Pyrroline-COOH_reductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11645">
        <property type="entry name" value="PTHR11645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03807">
        <property type="entry name" value="F420_oxidored"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14748">
        <property type="entry name" value="P5CR_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000193">
        <property type="entry name" value="Pyrrol-5-carb_rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00112">
        <property type="entry name" value="proC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F420_oxidored" evidence="3">
        <location>
            <begin position="2"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="P5CR_dimer" evidence="4">
        <location>
            <begin position="157"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="266" mass="28798" checksum="71B7361BB76D8DAA" modified="2019-11-13" version="1">MKIAIIGTGNLGKSIAKGLVTTNAITTLWLTKRNLESISDFEGYKNVSLTSDNLEAVQKSDILILAVQPSHLESILNDIKLSLTERHIIISTVTGFSIAKIEAIVGQEQFIIRAMPNTAIAVGKSMTCLCSNGQGSKRIKVAEAIFNRLGHSLVIPETQMQAATVVCASGIAFWMRLIRASTQAAIQLGFDAKEAQELAMYTSEGAASLLIQNKKHPEEEIDRVTTPKGCTIEGLNEMEHKGLSSSLIQGMVASFNKISNIKKEQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKW9</accession>
    <name>A0A5C6ZKW9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_02710</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="196" mass="22988" checksum="D58EF6F3373E1BE9" modified="2019-11-13" version="1">MKKLIIITLIVCFSCQKKRTIDPCVEIEKKYDSILSSNETFKNDPIYKFYSILEKETGKSTDSLLIQDYRDLAGKDSLINLYVWDRIHSINQNITTNNVYELFKGTFLLKPNHNKKYAQATKIIVDRDSVYIYKYDKLIISDKFTLINSSNKYIKGKIILKNYRLYLDGAIKSKLLIQIDDNGCMDCEQLQFYKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL48</accession>
    <name>A0A5C6ZL48_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GNAT family N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_04055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017255">
        <property type="entry name" value="AcTrfase_GNAT_prd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037663">
        <property type="entry name" value="Acetyltransf_GNAT_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="150" mass="16838" checksum="1249B3A2693E4D0A" modified="2019-11-13" version="1">MIKIAKAQLEDLAGIIAIEQDVFDTDSYPPFVVRQLFDISGDYFLVAKEKDKILGYALGGLNTKKQQGWVLSLGVHRDARGKGLGKQLTAQLIELLKAEYAEEIALTVYPDNTSAIKIYKDLGFVGETVLDNYFFDHEERVVMTLKISHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL66</accession>
    <name>A0A5C6ZL66_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF2480 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_08335</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018914">
        <property type="entry name" value="DUF2480"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10652">
        <property type="entry name" value="DUF2480"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="168" mass="19310" checksum="3E43E3C363490448" modified="2019-11-13" version="1">MQDEIVNRVALSKLMVVDLEDYYPEGERVPFDIKDWLYEGFVLREKEFRQQVKAHDWSQYDNQFVALSCSSDAIIPAWAFMLITMELQPFARKICVGNMEALETSIYQDIINGLDVLPYQDQALIIKGCAHKPVPLNAYILLSNKLRPVAKSIMYGEACSSVPLFKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL79</accession>
    <name>A0A5C6ZL79_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">O-succinylhomoserine sulfhydrylase</fullName>
            <shortName evidence="2">OSH sulfhydrylase</shortName>
            <shortName evidence="2">OSHS sulfhydrylase</shortName>
            <ecNumber evidence="2">2.5.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">metZ</name>
        <name evidence="5" type="ORF">ESY86_02180</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the formation of L-homocysteine from O-succinyl-L-homoserine (OSHS) and hydrogen sulfide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>hydrogen sulfide + O-succinyl-L-homoserine = L-homocysteine + succinate</text>
            <dbReference type="Rhea" id="RHEA:27826"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:57661"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 2 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homocysteine from O-succinyl-L-homoserine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the trans-sulfuration enzymes family. MetZ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.-" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00449"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071266">
        <property type="term" value="P:'de novo' L-methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071268">
        <property type="term" value="P:homocysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00614">
        <property type="entry name" value="CGS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02056">
        <property type="entry name" value="MetZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006234">
        <property type="entry name" value="O-succ-hSer_sulfhydrylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808">
        <property type="entry name" value="PTHR11808"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="2 3 4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2 3">
        <location>
            <position position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="387" mass="43020" checksum="B4ABF44FE5625D3A" modified="2019-11-13" version="1">MKHFETEAIRTQTERSQFQEHSTPLYLTSSFVFEDAEDMRASFAEEKQRNIYSRFINPNTSEFVEKICKMEQAEAGYAFATGMSAVFSTFAALLNAGDHIVSARSVFGSTHGLFTKFLPKWNIETSYFNVNKIDTIEGLIQPNTKILYAESPTNPAVDILDLEHLGAIAKKHKLLLVIDNCFATPYLQQPIKFGADLVIHSATKLIDGQGRVLGGVTVGRADLIREIYLFSRNTGPALSPFNAWVLSKSLETLAVRVDKHCENALKVAEYLETQDKVKLVKYPFLKSHPKYEIAKKQMKLGGNVVAFELKGGVETGRNFLNKLEMCSLSANLGDTRTIVTHPASTTHSKLSEEELLEVGISGGMVRISVGLEHVEDVIADLKQALEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL81</accession>
    <name>A0A5C6ZL81_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Fic family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_04215</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003812">
        <property type="entry name" value="Fido"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036597">
        <property type="entry name" value="Fido-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040198">
        <property type="entry name" value="Fido_containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13504">
        <property type="entry name" value="PTHR13504"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02661">
        <property type="entry name" value="Fic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140931">
        <property type="entry name" value="SSF140931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51459">
        <property type="entry name" value="FIDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fido" evidence="4">
        <location>
            <begin position="106"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="185"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="189"/>
            <end position="196"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="221"/>
            <end position="222"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for autoinhibition of adenylyltransferase activity" evidence="3">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="313" mass="35432" checksum="4B3807FCF129F451" modified="2019-11-13" version="1">MWEVDVSYRDTLQTTFNRLFEKANLLKTSRPLPQIALQKLKEALSIEWTYNSNSIEGNSLTLRETQLVLQEGITIKGVSLREHFEAKNHETAIDLLYNLLQPNYVLNSKDILALHALVLRSIEDDHAGRLRNGGVRISGANFIPPNASKVSQLLDDLVQFVVENPLGLNVIELASVFHHKFVYIHPFFDGNGRTVRLAMNLILMAQGFPPAIILTNDRQKYYKALNQANTGNYEKLMLLMCQALERTLNIYVSALPDSDLEYQPISSVVEDPSVPYGQEYVSLLARQGKIDAHKEGRNWYTTKAAVIAYMKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL96</accession>
    <name>A0A5C6ZL96_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-acetylmuramoyl-L-alanine amidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008745">
        <property type="term" value="F:N-acetylmuramoyl-L-alanine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02696">
        <property type="entry name" value="MurNAc-LAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002508">
        <property type="entry name" value="MurNAc-LAA_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01520">
        <property type="entry name" value="Amidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00646">
        <property type="entry name" value="Ami_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MurNAc-LAA" evidence="1">
        <location>
            <begin position="92"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="210" mass="23378" checksum="81B3C2D8DAFA67CE" modified="2019-11-13" version="1">MKKVLKNVSFVFLLLQLCIIFGQEASTQKRIIIDVGHGGKDSGAIGVNGIQEKDVVLDIANAILELNNDLEKPLNIYLTRYKDTLISLSDRTKLAKILKADLFVSLHCNHSDNPDARGIEVYTSRTQGKYSKQSVFMGFQIEKTLCKTIGFESRGVKFANFQVIRGTINFCPSLLLELGFLSNRDEGSYISDAINIQFIASTILLSIKNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLB1</accession>
    <name>A0A5C6ZLB1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_04370</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90609.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90609.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="79" mass="9322" checksum="4883A5EDC29104E3" modified="2019-11-13" version="1">MTYNISIYHENVKKVRYFTTGIGLTEKEFDTIWLNPENKKLRGTNKEIILKLKAIEKRANDEAKAMSVFDFSKFESKLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLS0</accession>
    <name>A0A5C6ZLS0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GNAT family N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07510</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="27"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="181" mass="20818" checksum="829B260960DB6CBA" modified="2019-11-13" version="1">MKIATFDSFEIAAIHDGDAWKICDFMVANADRLKRFFPKTLEQNLNPSLSKLFVAQKVEQFISNQEFVFTLKHSETRELAGLFYIKELDWKKKQGEFAYCIGYSFEGKGLTSKTVNALTLYAFDTLKLETLQIITHKTNLPSVSVAKNCGFEWIKTLKNEFTPNGGTALDMELYELKNKRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM10</accession>
    <name>A0A5C6ZM10_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">MotA/TolQ/ExbB proton channel family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_06360</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the exbB/tolQ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002898">
        <property type="entry name" value="MotA_ExbB_proton_chnl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01618">
        <property type="entry name" value="MotA_ExbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="64"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="102"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="MotA_ExbB" evidence="8">
        <location>
            <begin position="68"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD89960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="138" mass="15011" checksum="16EE26603CD5F063" modified="2019-11-13" version="1">MSITSLQSHFLIVNIFNDGGPIMMSLILICLLIALFFLVRGFLNAKKNPMLAHKMRELASDASLLGLVLGFLGSILGMISAFDSIEMLGDISTGMMASGLKVSFLTVLFGAFVFLLSRLGILILRAMLKQKSELEVKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM38</accession>
    <name>A0A5C6ZM38_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="143" mass="16688" checksum="0BF578631CCF4783" modified="2019-11-13" version="1">MTLELLRILLDFGLVVLIWMVQLLIYPSFIHFSSTNLIAWHKVYTKNMALVVMPLMLGQLVVYSASFIQEQNSFNTLGFVLTLILWASTFFQFVPLHNAISKNQFTADHLKLLVKRNWIRSFLWSVLFVLSLLEYASLLPKFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMC5</accession>
    <name>A0A5C6ZMC5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Biotin-dependent carboxyltransferase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_06270</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003778">
        <property type="entry name" value="CT_A_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02626">
        <property type="entry name" value="CT_A_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00797">
        <property type="entry name" value="AHS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AHS2" evidence="4">
        <location>
            <begin position="23"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD89807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="280" mass="30951" checksum="29A7FD85C3AC7175" modified="2019-11-13" version="1">MIELLKAGLYDSIQDLGRFSLQQFGVPYSGAMDQYSAKLANLILGNHHDAAVLEWTLLGPNLKCHSNALICVTGAVSDLKINKHAVKQNMALRIQAGDTLTFGAAQKGCRGYLAVLGGFQTELVMGSRSQYANITAEFRLKKGTRLPIKEQTLPKQLQKASVKTPTAHFDTKLIEVFKGPEYDALSETQQRALTSKTFTVSKDSNRMAYQLNEHFENELEPIFTSLVLPGSVQLTPSGQLVILMRDCQTTGGYPRVLQLSEQAIDRLAQKNIGAELRFEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMT0</accession>
    <name>A0A5C6ZMT0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Exosortase family protein XrtF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">xrtF</name>
        <name evidence="10" type="ORF">ESY86_05765</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026392">
        <property type="entry name" value="Exo/Archaeosortase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019127">
        <property type="entry name" value="Exosortase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026323">
        <property type="entry name" value="Exosortase-related_prot_XrtF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09721">
        <property type="entry name" value="Exosortase_EpsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04178">
        <property type="entry name" value="exo_archaeo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04128">
        <property type="entry name" value="exoso_Fjoh_1448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="84"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="116"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="150"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD90243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="183" mass="21342" checksum="DD193E9A09D725EC" modified="2019-11-13" version="1">MKSLFLKYKSVVVFILTFLAVYFVLSFAYNLYLEFSNGSIYYPDYITNLVAKQSDELLNTFGYDAKVLPHPDEPSMKVIVNGKYLARIIEGCNSVSVIILFVSFIIAFAGKLKTTFFYMLSGSVLIYVVNLMRIVILTIGLYNYPWRRDILHTVIFPMIIYGMVFLLWMFWVNRFSKLKKRHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMT7</accession>
    <name>A0A5C6ZMT7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">T9SS type A sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_01355</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022725739" evidence="1">
        <location>
            <begin position="20"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="domain" description="Por_Secre_tail" evidence="2">
        <location>
            <begin position="480"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD91262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="537" mass="57622" checksum="8447864DE690B5F2" modified="2019-11-13" version="1">MKKLYSFLLFTALCFTANAQLSKTMTVSGGTSVSIATGTTVTADNVNLKSTSDKFSSLMLDGDLLKDDAVTPTVVNYDRYVNVVGSASNNGGNDLISLPVKTADATFGDLLTYSADGGTTPNSSIIVNNPDPSFDTVYAFGPYSNSAGAYINYDEIIDGTVLLERGMGYRAATNNGETIRFTGTVSKADETVAITTTFTGADYNYWNTVGNPYPTYINAQVFYSENKDQLDVDAQAIYAYNSGTGSVSGFGTFGNFTIINDLTNETVNIAPGQGFLVAVDRDAIGNEIVFTQAMRVFSGTDDFILGRSDNQSQKLRLKAEQGSTNFATEIYFNDNATLGLDPGYDAGTFNGISSNFMIYSHLVEGNTGRNMAIQSLASTDMNDVIIPLGLKTAQGQQVTISIENSTLPAETQVYLEDNQSNTFTLLNSGDYTFTANTAISGTGRFFLRMGTATLSTPVTEANALKLFTTEQTLFIKGQLLAETQVSVYDIQGRLVLTSILAQGSDSNNIDASGLNTGIYIVKLNNEKQELTKKVIIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMU7</accession>
    <name>A0A5C6ZMU7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_01405</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="6"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD91272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="133" mass="15465" checksum="CC605AA442D51016" modified="2019-11-13" version="1">MRTEKTLMIVDDDEDDRFFFRSAVRKYNPSYKCVEAENGDDALQQLRKAEQLPDFIFLDLNMPKMDGRECLIELKKDSSLAKIPVVIYSTSEYKVDKELTVELGADYFLTKLSNLYELPEELLKAMNIVARKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMZ2</accession>
    <name>A0A5C6ZMZ2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GIY-YIG nuclease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05285</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035901">
        <property type="entry name" value="GIY-YIG_endonuc_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01541">
        <property type="entry name" value="GIY-YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82771">
        <property type="entry name" value="SSF82771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GIY-YIG" evidence="1">
        <location>
            <begin position="2"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="84" mass="9811" checksum="4B38EA6E58F317CF" modified="2019-11-13" version="1">MLDFVTYILASEKTANLYKGHTSNLIGRFKSHNGLSKKGWTVRYRPWRVVYVRFFATKSEAMGHEHWLKSGAGREWIKCHLKAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNI1</accession>
    <name>A0A5C6ZNI1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_05745</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0675">Receptor</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="domain" description="Plug" evidence="6">
        <location>
            <begin position="118"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="5">
        <location>
            <begin position="313"/>
            <end position="744"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD90240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="746" mass="85122" checksum="7A2BF9D6F8FACDD3" modified="2019-11-13" version="1">MKYILYIFCLLPITMSSQDKIEGIITEKTSDNTMFPLAGANVFWMGTSVGTVTDIDGKFSIPYQENYKKLIVSFIGFKTDTLTIESVKYIKHELKATSDLDEITLTARKQASSRSYMQAQNILTVSSDELLKAACCNLSESFETNPSIDVNFTDALTGARQIKMLGLTSKYILITTENIPSIRGASQAFGLSFIPGTWVESIQITKGAGSVVNGFESIAGQINTELRKPSTDDRLFVNFYGANSERMELNTHINTKVSEHWDTGFYIHGNSHKKKHDVNNDGFMDMPLYEQINVMNRWQYTNPEKGLVSFINVRYLNDSKQSGQLDFDPDTDKFTTNSWGSEIDTERFEMTSKLGYVNPELPWQILGAQLSFSSTNQISYYGLNLYDINHNSWYSNVIYNTIISDSRHKIKTGLDFTYDHYDELAINRDFERSERSFGGFFEYAFDDLSNFSMTAGLRFDTHNLLGEFVTPRLHVRYTPWEKSAFKASVGRGKRSANIFAENQSIFATSRSINILDSGGRIYGLDPEIAWNYGISYLQGFNLFGRKADITLDFYKTDFKNQVVVDWENANELNFYNLQGESYANSFQVELNYDMFERFAFRTAYKYYDVQTQYQVGKRSKPLTPEHRFFANASYETDVSQGQTTQWKFDATYNWLSEQRFSSTAANPEAFQLPEESPTVGTLNAQITRVFSPRFEVYLGGENITNVRQNNPILGAEDPFGPNFDTSFVYGPIFGSLYYAGLRFRIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNL2</accession>
    <name>A0A5C6ZNL2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_05915</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="228" mass="26410" checksum="D536475C65145016" modified="2019-11-13" version="1">MIRTLTCIALFSVMLGCKSETKKTDDTSANPSEEKVELTAFENIAKAYGIDKWKDVKEIDFTFNVDTDGKHFQRAWQWQPKTNDVVMMTEKDTVRYNRASVDSLSLKADQAFINDKFWLLSPFQLVWDEDVHISVPVKEAAPISKTQLNKITLTYLGDQGYTPGDAYDFFYDDDYMIKEWNYRKGNSETPTMSTTFENHEDFDGIKIAKDHKKADADWNLFFSDIKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPH5</accession>
    <name>A0A5C6ZPH5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha-amylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_02880</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043169">
        <property type="term" value="F:cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006048">
        <property type="entry name" value="A-amylase/branching_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02806">
        <property type="entry name" value="Alpha-amylase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aamy" evidence="1">
        <location>
            <begin position="46"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="628" mass="72195" checksum="B0ED97844ACA629C" modified="2019-11-13" version="1">MKHTTVLIAIVMSSLFGCKTEKTLQEPNEAKMETKMETNRKEVVYQVFTRLFGNTNTTNKPWGTLEENGVGKFNDFTDKALNEIKDLGVTYIWYTGVPHHDVITDYTEYGISNDDPDIVKGRAGSPYAVKDYYNVNPDLAENVENRLAEFEALIERSHKAGLKVIIDIVPNHVARNYQSLTNPEGVTNFGAEDDTTVVYDVNNNFYYNPGEAFKVPNWKNGYQPLGGEKQPLADGKFEENPAKWTGNGSRASQPDMNDWYETIKVNYGVSPDGDKDFDELPQAFENKDYQAHYAFWNGKTVPSSWKKFKDIALYWTQRGVDGFRFDMAEMVPVEFWSYMNSAIKTENPDAFLLAEVYNPSMYREYIKKGKMDYLYDKVQLYDTLKHVMQGRGKTDYIPPIQEDLKDIEHHMLHFLENHDEQRIASPDFAGSAEKGKPAMVVSATISSSPTMIYFGQEFGEAAKEDLGFGDPTRTSIFDYGSVPSVVRWVNDNKFDGGKSTEDEKQLRDFYKRLLNFTINSSALVGQYEDIHSFNRQNTEWYNDQVLSYVRWSDDEKLVVISNFNAENTYGFELQIPSAIIEKWNLEAGEYEMKDQLYKSYKTTLKVEAEKAYLRIDIKPLESFILKLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZQR7</accession>
    <name>A0A5C6ZQR7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">LysR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_01200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LysR transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005119">
        <property type="entry name" value="LysR_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000847">
        <property type="entry name" value="Tscrpt_reg_HTH_LysR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00126">
        <property type="entry name" value="HTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03466">
        <property type="entry name" value="LysR_substrate"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00039">
        <property type="entry name" value="HTHLYSR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50931">
        <property type="entry name" value="HTH_LYSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH lysR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD91233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="312" mass="35300" checksum="94E0BF0954C4897A" modified="2019-11-13" version="1">MTITQLRYVLAIAEYKNFTNAAEKCHVTQPTLSTQIQKLEDELDILIFDRSKKPIELTDVGRKIVQQAKNIVNESDRIKDIVDQQKGFIGGEFKLGIIPTIMPTLLPMFLKTFIKKFPKVILKIEEMTTDDIITKINDGHLDAAIVATPLKIENIKERVLYYEPFVGYVPDDHALSSLKKLTVSDLNLDDILLLEDGHCFRDGVLNLCNSIKDGTIDKFQLESGSIETLIKLSNEGLGMTLLPYLHTIDLNENMQSKLRYFSPPPPAREVSLIYHKSELKMQIIESLHKVISSIIRGAIAFQNVQIISPLPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZR12</accession>
    <name>A0A5C6ZR12_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="142"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="161" mass="17920" checksum="6DB3EC7350381A1D" modified="2019-11-13" version="1">MLQNKTSAKICGIRGKQTEACEALKPVNRADERRENVESQGMLQNKTSAKICAICGKQTEACEALKPANLADERRENVESHGILQNKTSAKICAICGKQTEACEALKPANLADERRENVESHGMLQNKLRENLRHLRETNRNAFNSKPVVQEPSSRSFKTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZRE0</accession>
    <name>A0A5C6ZRE0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cysteine desulfurase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_00805</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016454">
        <property type="entry name" value="Cysteine_dSase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005572">
        <property type="entry name" value="NifS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotran_5" evidence="4">
        <location>
            <begin position="4"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD91160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="384" mass="42470" checksum="F6D4F0A693C876FB" modified="2019-11-13" version="1">MKSVYFDSAATTQMRDEVIERMANVMKDYYGNPSSTHGFGRHAKSLLETSRKTIASFFNVSAAEIIFTSGGTEADNLVLRSAVKDLGVTEIISSKIEHHAVLHTLDELQKEFPISVNYVNVLKNGHIDMDHLEQLLQSPKKTLVSLMHINNEIGNLLNIERVANLCKAHQALFHSDTVQSVGHYQMDLQEIPIDFMAASAHKFHGPKGVGFAFLRKNSGLRASIYGGEQERGLRAGTESIHNIVGMADALSLAYKHLEAEQEYTLSLKTYFIDQLQDAFPDIQFNGDCANPEGSTYTLLNVCLPFTADKASLLSFQLDLKGIACSRGSACQSGSSQNSHVLTAILEDDYLKRPSLRFSFSSFNTKEDIDYVVEVLKEFSGNGMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAH7</accession>
    <name>A0A5C6ZAH7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Universal stress protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_18645</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal stress protein A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000033">
        <property type="protein sequence ID" value="TXD86949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="2">
        <location>
            <begin position="4"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="282" mass="32649" checksum="B4FD0E2996DE4AD8" modified="2019-11-13" version="1">MLSILMPTDFSENSMNAIKYALEFFKYQKTDFYFMHAYRNEFYDDEQLVSREVFDTVLESVKKQSKSNMDELLQKVEAIATNTRFNYHGISAFNTLVEEANQISDEHNIDLIVMGTKGKSDDRSIVFGSQTFQVLKYVQCPVLAIPTNYTNTQPKRILFPTNYLIPYKRRELKLLSVLAKSYRSTIDVLYVSKSKGLSMRQEDNQSFIKDTLEGNTLNFIQERNKSVSETIKAHLKDNSVDLLTMVNTQHSFLEDMLFPSTIDKVSLGLDIPLLAMQNTRRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAP6</accession>
    <name>A0A5C6ZAP6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19305</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000039">
        <property type="protein sequence ID" value="TXD86758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022815789" evidence="1">
        <location>
            <begin position="23"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="299" mass="34960" checksum="A43DACDF5F229C66" modified="2019-11-13" version="1">MKRLILFVAIFCSSLGVLQAQAWMNNLDFAKRLALTQNKMLFVMWESSTMYPLPVRINDAKGQTYLVENLFESEELNRLIWEHFVPVSINEDNYEAMYDAIESRRSQDYLDKFNDDSIKIMDANGMILNMSVQNDIYLNLSEFIARYALDTSFLSLEQHSYAAEANFYNAFYLSSKYLDYTMFANEALRPELMALSMVYLNEARAKIKDEDQQEQAAMQQRSDLLELESFLLKDKPRKVLRKLRRLDADEIAAVNTEFVAFLYYTAYRLIKDIESSKAWMGQVSSVNLKKSDMIVRVFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZB38</accession>
    <name>A0A5C6ZB38_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycoside hydrolase family 65 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_19830</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000049">
        <property type="protein sequence ID" value="TXD86591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005195">
        <property type="entry name" value="Glyco_hydro_65_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005196">
        <property type="entry name" value="Glyco_hydro_65_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037018">
        <property type="entry name" value="Glyco_hydro_65_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03632">
        <property type="entry name" value="Glyco_hydro_65m"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03636">
        <property type="entry name" value="Glyco_hydro_65N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022943723" evidence="1">
        <location>
            <begin position="21"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_65N" evidence="3">
        <location>
            <begin position="36"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_65m" evidence="2">
        <location>
            <begin position="307"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_65m" evidence="2">
        <location>
            <begin position="529"/>
            <end position="645"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD86591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="676" mass="76067" checksum="D0715D20ACBC61C6" modified="2019-11-13" version="1">MKTALSLLVCLIFVSINAQNEGWNIETTTSSNYTGVAMANGRIGILPSERLFKTEQIILNNVYDKESPLGVSRILKGMNFGNLEIEIDNEKLTAQNIENWSQTLHMKEAYFETSFTYKDKADISYKIYALRNVPYSGYFDFNITAKKDISVKVTGSIETPEEYLEPLSTYRVLKDNEVTMPILQTVAKSRLGRHVVGTSATFVWHQLNSGDEHQRPTLVHEKISEYNNQLSFVETVKKGTSLDFAWTAAQCTTQDFNDPQSESERFVIFNLLTPRNDLINQHTEMWKQLWEGDIIIEGDLQSQLDVRLALYHLYAFARGDSNLSIAPMGLSSQNYNGHIFWDTELWMFPPLLVLNQDIARSLVNYRSDRLDKAKQKAINFGYKGAMFPWESDDTGEEATPAWALTGTFEHHITADVAIAFWNYYLVTKDKSWLKERGYPMLKEVADYWVSRATLNADGSYSIKNVVGANEFAPNVDDNAFTNGAAITALNYAEKSAKELGLAANPLWAEVASKIRIHKFPDGTTMEHSNYKGERIKQADVNLLTFPLDIISDEATILKDLKYYEPKLAEEGPAMGKSVFAIIYARLGDADNAFRLFKESYEPNKRPPFGALSETATGHDPYFATGAGGMLQTVLFGFGGLHLTEDGIIQKGAILPKQWTSLTIKGVGIDKKVYVIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZB52</accession>
    <name>A0A5C6ZB52_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000121">
        <property type="protein sequence ID" value="TXD85848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD85848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="96" mass="10527" checksum="F4988315F1F450CD" modified="2019-11-13" version="1">METESKSEKRTLLNGIGINIFAIFIGIIITLIIASNTSSDMPASSNHGAIFPFFNAILFGIITLIAYLSLKNIFKNYSWVITLIGILITIFASTKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZB97</accession>
    <name>A0A5C6ZB97_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_20675</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000102">
        <property type="protein sequence ID" value="TXD85991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD85991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="123" mass="15520" checksum="9DF5D384220A3119" modified="2019-11-13" version="1">MLFWKTENRIEPKRDFYSKIKEYYIGFSDNQIPIELLNEIISKVTDEIYSDYKRFWKQYPKSRKRYSTLKMEDVEHPFIHYLITDYLITKKVKECRDFSKILFRMNNLEFEEYEKQKHWYETK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBE4</accession>
    <name>A0A5C6ZBE4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_17340</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000026">
        <property type="protein sequence ID" value="TXD87325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="75" mass="8798" checksum="C8DB940843E34C9E" modified="2019-11-13" version="1">MEKVIDKAKEFENQNMKSLSTSDRVKISREAKRLILALNTIYKEKKDEKIMDLMKSLTKMKRKVEKRLNGKPLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBI9</accession>
    <name>A0A5C6ZBI9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L35</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">rpmI</name>
        <name evidence="6" type="ORF">ESY86_18760</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the bacterial ribosomal protein bL35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000033">
        <property type="protein sequence ID" value="TXD86967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.410.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00514">
        <property type="entry name" value="Ribosomal_L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021137">
        <property type="entry name" value="Ribosomal_L35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018265">
        <property type="entry name" value="Ribosomal_L35_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001706">
        <property type="entry name" value="Ribosomal_L35_non-mt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037229">
        <property type="entry name" value="Ribosomal_L35_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33343">
        <property type="entry name" value="PTHR33343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01632">
        <property type="entry name" value="Ribosomal_L35p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00064">
        <property type="entry name" value="RIBOSOMALL35"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143034">
        <property type="entry name" value="SSF143034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00001">
        <property type="entry name" value="rpmI_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00936">
        <property type="entry name" value="RIBOSOMAL_L35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD86967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="65" mass="7513" checksum="8A9F220EDDD6256D" modified="2019-11-13" version="1">MPKMKTKSSAKKRFKLTGTGKIKRKHAFKSHILTKKSKKRKLALTHDALVHDADMNNVKIMLRLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC21</accession>
    <name>A0A5C6ZC21_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_18855</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000034">
        <property type="protein sequence ID" value="TXD86927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="67" mass="7823" checksum="164A9D04CF0FB70E" modified="2019-11-13" version="1">MVALLKRGADKKTIKNVLKILSRDSKSKGVDVYSFVGRINLKEGALKLQKELRDEWERFFRDISDRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC22</accession>
    <name>A0A5C6ZC22_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19805</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000048">
        <property type="protein sequence ID" value="TXD86597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase" evidence="1">
        <location>
            <begin position="42"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="365" mass="42542" checksum="7A199CB9D7E46BEA" modified="2019-11-13" version="1">MIKKIQNLLIFLVLVISFTSCHSQKKIINLAGFDVKTDSINTFLKSRMDSLNIPGLSIAVINDSKVVYHETFGFANLEKKIPITEKTIFEGASISKSVFAFFVMKFVEEGKLDLDKPLFEYLPYEDIAYDDRYKKITARMVLSHRSGFPNWRENEEDKKLKIKFEPDTDYEYSGEGYQYLAMVLKQIEDTDWNGLEMLFQKKVAKPLKLEHTVFIPTSYTNEHKAEPYNNQCEWIDLKNNYWYKKDKGVFVSSSSIHSEPIDFSKWMIGVMNKEILSKESYNELFKHRSTISTSSTGINVYYTLGYITADKPYNSTYFHGGSNDGFTCYYLMDISKKWGYVLFTNSENGERLGNEVWNYFEKESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC94</accession>
    <name>A0A5C6ZC94_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18375</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000031">
        <property type="protein sequence ID" value="TXD87026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022878185" evidence="1">
        <location>
            <begin position="28"/>
            <end position="640"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="640" mass="65359" checksum="83489D9C9BDC0362" modified="2019-11-13" version="1">MKIMKSLSKLLGLSIMAALLITSCSNDDDNEPITPTGPETTLTGVITADRILDPTKQYTISGPVSVASEVKLTIPAGTVIVSEVGVENYLAVLQGGEIDVQGTATSPVVMKSNGASGSWGGLLLCGNSTTTEGANASAEVAGLIYGGNNAGDSSGNIDYLIIRDSGAQINANSQFNGLTLYAVGSGTTIDNVAVINGTDDGVEFFGGTVNVNNFYAENLEDDAVDWTEGWSGTLTNTYVFNSTASFSTAIEADGVNNNPTLINFTAISATGGVAVQIKNNSGATINGLTITGFDTSFDFRDDAPASNLQVDDADADTADDAVFASSSTNASLFAWVTNASASSGNQLPSNITASVTLDASVEYTVAGPVLVNSGATLTIPAGTQIVSQSGTANYIAVLKGGKLDIQGTAANPVEMRSGDGNAWGGLLLCGNASTTEGVNAIAEVGGLIYGGTNDADDSGAINYLILRNTGAQINADSQFNGLTLYAVGSETSIQNVAVIGGADDGVEFFGGTVSMTNFYAENLEDDSVDWTEGWNGTLTNTFVKLTISGFSTAIEADGVNAEPTLVNFTAVSTTGGTGIQIKNNSGAIINGLTLTGFDTQFDFRDGAPSSNLPIDGVNAAEEGTFATSTSVEADFAWINN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCG1</accession>
    <name>A0A5C6ZCG1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19570</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000043">
        <property type="protein sequence ID" value="TXD86690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="104" mass="11609" checksum="17A4190F4E8E37D2" modified="2019-11-13" version="1">MKKILFILLCSFVSFGFTNERIEPISENESAEITLPVKVETYNFPYENGTITLTIFDNGICEQGTVTGTLSTHCDDDGIADYVWSGTICREHIDALIMQFNASC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCS5</accession>
    <name>A0A5C6ZCS5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HupE/UreJ family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18840</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000034">
        <property type="protein sequence ID" value="TXD86925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032809">
        <property type="entry name" value="Put_HupE_UreJ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13795">
        <property type="entry name" value="HupE_UreJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="193" mass="21867" checksum="EAFDBE34EA6ED807" modified="2019-11-13" version="1">MIDLFLSNFKDGVYHVLNINAYHHILFLIVLTVPYLFKDWKRVLVLITIFTLGHCVALALTVYNVINVNSKLIGFLMPMTIFVIALYNIFTAGKKAQNEKIGLLFFISLFYGLVHGLGFEATFNSMITASENKPIALLEIALGLEVGQFVVAFIVVFLSFLCQTIFRFSKRDWVMVISAIVLGFVLPMLLRHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCV8</accession>
    <name>A0A5C6ZCV8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AarF/ABC1/UbiB kinase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17290</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000026">
        <property type="protein sequence ID" value="TXD87316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004147">
        <property type="entry name" value="ABC1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03109">
        <property type="entry name" value="ABC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="1">
        <location>
            <begin position="122"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="436" mass="49917" checksum="F84DF3E1232C48AA" modified="2019-11-13" version="1">MKTIDKIPTSKIQRASKLVTTGAKIGVNYLKYYGDKLSKTELEAKDRLNNNNATDIYDGLKQLKGSALKVAQMLSMEKSIMPQAYVEKFSLAQFSVPPLSPPLVLKTFKKYFGKLPSEIYDTFNATSVNAASIGQVHLAEKDGKKLAVKIQYPGVAESIASDLAMVKPIAMSMFNIKGKGSDKYFKEVENKLREETDYILEVKQSKEISKACKHIPNLKFPEYYEDLSSERIITMDYMDGEHISEFVAHNEDQDMSNKIGQALWDFYMFQIHNLKKVHADPHPGNFLISKTGELIALDFGCMKIIPDEFYTPYFDLAKEEHMADPAYFKNKLYELEILREDDNAEEVKFFTAMFHEMLSLFTQPLHSEVFDFSDPSFFGKIAALGEKYSKNSELRKMNANRGSQHFIYMNRTFFGLYNLMFDLKAKGIKINNFHTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCY0</accession>
    <name>A0A5C6ZCY0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000053">
        <property type="protein sequence ID" value="TXD86531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023138587" evidence="1">
        <location>
            <begin position="20"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="180" mass="20629" checksum="484C9C119D9CB887" modified="2019-11-13" version="1">MKKIIILLAVTVSFYICKAQTVYSFDVEPENMTSDNYYIKDLNNEHDAIIGTWKWEEGNSTFEITLQEFQMYNYPENSTRYYDAIFGKYKYIENGNLIAEVNSIQPFPNSKLVFNFKSSTEYSIVIKDMVSLKSMVGEFQIISGNTATLNLWRSEGVRVNSPGDNGIEFSLPTSISLTKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD49</accession>
    <name>A0A5C6ZD49_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">50S ribosomal protein L11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 11" type="primary">rplK</name>
        <name evidence="11" type="ORF">ESY86_16300</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 8">Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.</text>
    </comment>
    <comment type="PTM">
        <text evidence="6 8">One or more lysine residues are methylated.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the universal ribosomal protein uL11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00349">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00736">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000911">
        <property type="entry name" value="Ribosomal_L11/L12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036796">
        <property type="entry name" value="Ribosomal_L11/L12_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006519">
        <property type="entry name" value="Ribosomal_L11_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020783">
        <property type="entry name" value="Ribosomal_L11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036769">
        <property type="entry name" value="Ribosomal_L11_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020785">
        <property type="entry name" value="Ribosomal_L11_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020784">
        <property type="entry name" value="Ribosomal_L11_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661">
        <property type="entry name" value="PTHR11661"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00298">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03946">
        <property type="entry name" value="Ribosomal_L11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00649">
        <property type="entry name" value="RL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46906">
        <property type="entry name" value="SSF46906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54747">
        <property type="entry name" value="SSF54747"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01632">
        <property type="entry name" value="L11_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00359">
        <property type="entry name" value="RIBOSOMAL_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0488">Methylation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6 8" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L11_N" evidence="10">
        <location>
            <begin position="9"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L11" evidence="9">
        <location>
            <begin position="71"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD87593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="146" mass="15505" checksum="D3DB08CAD63F34E8" modified="2019-11-13" version="1">MAKELSKVVKLQVRGGAANPSPPVGPALGAAGVNIMEFCKQFNARTQDKAGKILPVVISVFKDKSFDFVIKTPPAAVQLMEATKVKKGSGEPNRKKIAKVTWDQVKAIAEDKMQDLNAFNVHAAMKMVAGTARSMGITVKGGEAPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDI6</accession>
    <name>A0A5C6ZDI6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">WD40 repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_15885</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="G-protein_beta_WD-40_rep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037783">
        <property type="entry name" value="Taf5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013979">
        <property type="entry name" value="TIF_beta_prop-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19879">
        <property type="entry name" value="PTHR19879"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08662">
        <property type="entry name" value="eIF2A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="SSF50978"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="11"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="eIF2A" evidence="4">
        <location>
            <begin position="132"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="179"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="221"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="268"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD87789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="307" mass="34626" checksum="A6F4E3E68FEBAC84" modified="2019-11-13" version="1">MKIEVNKVAQLTGHNAPIYALDKGTAEHLIFSGGVDKVIAQWDLETFQSEKFVARFLAPLYSICHIHQKQWLLAGTSNGMDHIFDLEKNEDIAILNNHTSQVFNISYSIETNCIYTSGGDGYLAIYALDTLVLIKMIKLSDEKVRHLDFNYATSEIAVATGEGNISIFDLKTFLEKKIFVGHQLSSNVVRFSPDGKLLLTGGRDGHLNIWQVESYELIKSIPAHDWAVYDIAYSPDATLFATASRDKTLKIWDSKTFQLLNVVDRENNDGHQFSVNKLIWSAYNNYLISASDDKTIIVWEVNQNESL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDN5</accession>
    <name>A0A5C6ZDN5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4129 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000021">
        <property type="protein sequence ID" value="TXD87651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="245" mass="28606" checksum="01FE9D610D240FA2" modified="2019-11-13" version="1">MCLIFFGIALLSNAYVVKQEIPEALIAQETIKKDRAPLDIREYQDLSEKYEGSDFIYERSTANSGWWTRFKQWLSDFFSSLFDFQSDAQASDFTDIVLKIFYVVIFLLVVFFIVKAIINKEGNWVFGKSSDKSIIPVSDIENNIYATDFKTIIAEAEANGNFRLAIRFYYLWLLKQLAEMELIDYDVEKTNSDYHNEITSEVTKKEFSYTSYLYNYIWYGEFAIDQIQFNKAKHAFSKLLNSLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDW0</accession>
    <name>A0A5C6ZDW0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Beta-glucosidase BglX</fullName>
            <ecNumber evidence="6">3.2.1.21</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">bglX</name>
        <name evidence="6" type="ORF">ESY86_16105</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="6"/>
    <dbReference type="EMBL" id="VORO01000021">
        <property type="protein sequence ID" value="TXD87674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102483">
        <property type="term" value="F:scopolin beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019800">
        <property type="entry name" value="Glyco_hydro_3_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="SSF52279"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00775">
        <property type="entry name" value="GLYCOSYL_HYDROL_F3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023037125" evidence="4">
        <location>
            <begin position="22"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="domain" description="Fn3_like" evidence="5">
        <location>
            <begin position="659"/>
            <end position="728"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD87674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="739" mass="81471" checksum="8B03B237DA130D02" modified="2019-11-13" version="1">MKRITLYFCFLFVLWAGSGFAQNNEAKVDSLMNLMTLEEKIGQTVMYGGGWSVTGPTTKTDYVKYIKAGSVGAMLNVYTAKATRDLQKTAVENTRLGIPLLFGYDVIHGHRTIFPINLGLAASWDINLIEQTSRIAAEEASAEGLHWTFAPMLDIARDPRWGRISEGSGEDVYLASVMAKAYVRGFQGDDLSKNNTILATAKHFVGYGAAQAGRDYHTVNMGEGELRNVYLPPFKAAVDAGVETFMTAFNELNGVPSTGDKFIFRDILRGEWGFEGFVVSDYTAINELIPHGFAKDSTDAARLAMLAGTDMDMMGHVYRKHLKELITDGKIDVNLVNESSRKILLAKFKLGLFDDPYRYSDEKRQTETIYKPEFLKVARESAAASSVLLKNDNKSLPLDRTKTIALIGPLAKDDYHINGNWGGAGDRQGKSISVFEGLQDYLKANQILYAKGCDILSDDESGFEEAIAAAKKADVVVLVMGEDHGMSGEAASRTNLKIPGLQPKLIQKIREAVPNKKIVLVLMNGRPLNLSDEVDQVDAILEAWFPGSMGGSGIADLLYGAYNPSGKLTVTFPRNVGQVPIYYNMKNTGRPIPESNPTEDYKSNYIDAPNTPLFVFGHGLSYTSFEYSDFKLSSESIGFEDTLTASVTVSNTGDVDGHEIVQLYIHDKVGSVTRPVKELKGFEKIWLKKGERQTVSFTITAEDLKFYNNSMQFTVEPGAFEIAIAPSSDFKFEHGFILN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE03</accession>
    <name>A0A5C6ZE03_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DMT family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_15255</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="185"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="216"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="247"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="273"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="6"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="154"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="297" mass="32791" checksum="642A5AFFD74B04ED" modified="2019-11-13" version="1">MNSRAFGIFAVIMVQVLYGLNYTFAKNVMNENYVKPFGFVVLRVIGAAALFWLLSLFLKSEKIEKKDFISIFAAAVFGVGLNMLFFLKGLEYTTPIHASVITTITPIVILILSAIFLSEKLTKLKIIGVFLGFCGGVLLTAFGESTRVGDNVALGNTFIFLNAISYSIYVILVKKLTAKYHPFTFIKWMFLFGIVLVLPFGYAQATEIEWNTFSPYIWFSVAFVVVGATFGTYFFNPISIRLLKASTVGVSIYLQPVFAGLFALLMGADSIDAVKIMAMCLIFAGVFLVTKKSKASV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE93</accession>
    <name>A0A5C6ZE93_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">2Fe-2S iron-sulfur cluster binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_13250</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002888">
        <property type="entry name" value="2Fe-2S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036884">
        <property type="entry name" value="2Fe-2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01799">
        <property type="entry name" value="Fer2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47741">
        <property type="entry name" value="SSF47741"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="2">
        <location>
            <begin position="19"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="172" mass="18708" checksum="4DAE27DF3164809E" modified="2019-11-13" version="1">MHDKNSSNTANFSSNSNATKVQLHINKTTLHLHVMPWVSLLDAIRDHGKLTGTKKGCDHGQCGACTVICDGKRILSCLTLAVMKDGSEITTIEGIANGEVLHPLQTAFIEHDAFQCGYCTPGQICSAIAMLEEGKADTRDEVKEQMSGNLCRCGANTNIIDAIMEFKDKRNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEQ6</accession>
    <name>A0A5C6ZEQ6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cytochrome c oxidase subunit I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_14385</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the heme-copper respiratory oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070469">
        <property type="term" value="C:respirasome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004129">
        <property type="term" value="F:cytochrome-c oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009060">
        <property type="term" value="P:aerobic respiration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.210.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023616">
        <property type="entry name" value="Cyt_c_oxase-like_su1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036927">
        <property type="entry name" value="Cyt_c_oxase-like_su1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000883">
        <property type="entry name" value="Cyt_C_Oxase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023615">
        <property type="entry name" value="Cyt_c_Oxase_su1_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10422">
        <property type="entry name" value="PTHR10422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00115">
        <property type="entry name" value="COX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01165">
        <property type="entry name" value="CYCOXIDASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81442">
        <property type="entry name" value="SSF81442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50855">
        <property type="entry name" value="COX1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00077">
        <property type="entry name" value="COX1_CUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5" id="KW-0349">Heme</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0679">Respiratory chain</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="88"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="139"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="222"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="283"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="316"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="348"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="385"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="419"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="457"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="504"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="domain" description="COX1" evidence="7">
        <location>
            <begin position="22"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD88072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="597" mass="66630" checksum="2E3D28A026618AB2" modified="2019-11-13" version="1">MSAHADIEAHDDQAHHHHKETFITKYIFSQDHKMIAKQYLITGTIMGVIGVLMSMMMRMQLAWPEEPNVLFEALLGKWAPDGVMDADIYLALATIHGTLMVFFVLTAGLSGTFSNLLIPLQIGARDMASGFLNMVSYWLFFLSSVIMIGSLFVEAGPAAAGWTIYPPLSALPMAQGGSGLGMTLWLVSMGIFIASSLMGSLNYIVTVINLRTKGMSMTRLPLTIWAFFVTAIIGVVSFPVLLSAALLLIMDRSFGTSFFLSDIFLQGEVLHYQGGSPVLFEHLFWFLGHPEVYIVILPAMGLVSEIISTNARKPIFGYRAMVMSILAIAFLSTIVWGHHMFVSGMNPFLGSVFTFTTLLIAIPSAVKAFNWITTLWRGNLQLNPAMLFAIGFVSTFITGGLTGIILGDSALDINVHDTYFVIAHFHLVMGISALYGMFAGIYHWFPKMWGRMLNKNMGYLHFWVTAICAYGVFFPMHFIGMAGLPRRYYTNTNFPLFDDLQNTNVVITVFALVGGAFQLVYLYNFFASMFIGEKAVQNPWRSNTLEWTTPVEHIHGNWPGAIPHVYRWSYDYSKPGHDEDFVPQNVPLKEGEEELQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZET5</accession>
    <name>A0A5C6ZET5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_14550</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023132015" evidence="2">
        <location>
            <begin position="21"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="74" mass="8372" checksum="E4B7E9DC2867DA5F" modified="2019-11-13" version="1">MKRNLLFLLFSFVFFLQTNAQCAMCRAVLESEEGQVTAVGVNDGIMYLMAVPYILVAGIAFAIYWQFIRGKKTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFA8</accession>
    <name>A0A5C6ZFA8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">T9SS type B sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_14615</name>
        <name evidence="1" type="ORF">ESY86_18630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000033">
        <property type="protein sequence ID" value="TXD86946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026341">
        <property type="entry name" value="Bac_Flav_CTERM"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04131">
        <property type="entry name" value="Bac_Flav_CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="37" mass="4455" checksum="75734FB5223498D1" modified="2019-11-13" version="1" fragment="single">TYNGGQVPTSDYWFVVEYQEQQAQTTREFKAHFTLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFS4</accession>
    <name>A0A5C6ZFS4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4258 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10355</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="126" mass="14411" checksum="0704F61B30274B72" modified="2019-11-13" version="1">MRFIHRLGYYLGGFAIGLLLLAFFLSGKRTSCSYGPDARTIKNINLKKRLYSEEARLNMSQFQLDTLQVSELINSGDVNFSESDTKGDACHTYLIENEFENQDMELWIENCDSVATVQSIVLRKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFU6</accession>
    <name>A0A5C6ZFU6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="68" mass="7638" checksum="9B661FC366C210DB" modified="2019-11-13" version="1">MRKFAMMLVFLFTLSTVFTSCRDEKTPDEQVEDAMDDAGDAIEDASEDVQDAAEDLEEEIDEAAEENN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFV7</accession>
    <name>A0A5C6ZFV7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">S9 family peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_12435</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022776970" evidence="2">
        <location>
            <begin position="26"/>
            <end position="762"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9" evidence="3">
        <location>
            <begin position="548"/>
            <end position="762"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="762" mass="86923" checksum="5AFE95410DEA7253" modified="2019-11-13" version="1">MKNCITKLRYIISVVSLLCTVVSGAQNIEGTWTGELEVQGVTVEMSFNVSETDGVYSSTFDMPLQGAIGIPLENTEFENSVLTIESEKYKLKYIGELNEGQLKGTYTQLGKAYVFNLNKTEKSLPGDTALPSSEEELRKIAALETEQFKYSVEDFFEKPSLSMFRISPDGNYISYRKKDENGKNNVIVKDLRTQKEMVAIYEKEDLVRSYFWKGNDRLIYLQDKGGNENYHLFGANPDGSNNVELTPYDKTMVQLANVLQNDPNHMVITMNKDNEQLFEPYKININTGKLEKLFDNTDPTTPISGYTFDNDGVLRAYSKLQEGKYFENFYKNSETNEFEFRNQTDFENNDGILAFDYTTNNPDDVYLVSNLDSDKYEVYKYDMKTNKKLATVFKNDTYEISSMVISSKNRNYEIDYYSYQGAKNTMVPVSKLYKNIYERLTKEFGDKEISILSYDKNETQFIVHISSDKLRGIYYLYNIETNAIEELANMLPHLEEKDMAEMRPISFISRDGKTLHGYITLPKAALNGKSVPLVLNPHGGPFGVRDSWTFSDEAQLFASRGYATLRVNYRGSGGYGKAFQISGHKQIGRAMIDDLEDGVKYVINQGWIDEERVAVYGASYGGLATLQSLIKTPGMYVCGVDYVGVSNLFSQLENFSGVRKSYIQWYKDRYYDPENTIEHKIMTDASPALNADKISQPLLVIQGANDPRVKIEQADQIVKNMRARGIDVPYMVKYDEGHGFAHEANRIELYETILGFFAQHLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG16</accession>
    <name>A0A5C6ZG16_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_13690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13443">
        <property type="entry name" value="HTH_26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="13"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="69" mass="7575" checksum="92C06523A3BBEA13" modified="2019-11-13" version="1">MPILINLDVMLAKRKMQSNELADLVGITAANLSILKTGKAKAIRFSTLEAICKALDCQPADILEFHEHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG19</accession>
    <name>A0A5C6ZG19_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Restriction endonuclease subunit S</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_11525</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-I restriction system S methylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.220.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000055">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044946">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01420">
        <property type="entry name" value="Methylase_S"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0680">Restriction system</keyword>
    <feature type="domain" description="Methylase_S" evidence="4">
        <location>
            <begin position="26"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="Methylase_S" evidence="4">
        <location>
            <begin position="237"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD88856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="441" mass="50371" checksum="13EBA31BD73ED161" modified="2019-11-13" version="1">MEAVVERTKRYENYKNSGVEWLGEIPEHWEVRRIKYLFNEINERSENGSEDLLSVSQYTGVTNKTDKVEDGGMLTNALTLEGYKKVQKGDLVSNIMLAWNGSLGFSPFDGITSPAYSIYRLYDGNVKRYFHYLLRTELYKAEYKRNSSGVIESRLRLYTDDFFNILSILPPLEEQTAIAEFLDDKTTKIDQAIAIKQQQITLLKERKQILIHKAVTRGLDDTVALKDSGVEWIGEIPEGWEAKALKYFCFITKLTGFEYTNVWKTDSEGQIIALRGFNIQSGELDLSETEAISEKLSNSLQRTKLYKNDIVYPCTGTIGNAALIKEDNKFHINQNIARICLQSKEMFPEYFLKSLLSYATKSQIDFNNSSQMQPVILIGSLRNIKISFPPLLEQKKISDYIETASQKFETAICLKQQEISTLKEYKGSLINSVVTGKVKVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG35</accession>
    <name>A0A5C6ZG35_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Lipoprotein signal peptidase</fullName>
            <ecNumber evidence="6">3.4.23.36</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Prolipoprotein signal peptidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Signal peptidase II</fullName>
            <shortName evidence="6">SPase II</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">lspA</name>
        <name evidence="7" type="ORF">ESY86_13825</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">This protein specifically catalyzes the removal of signal peptides from prolipoproteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>Release of signal peptides from bacterial membrane prolipoproteins. Hydrolyzes -Xaa-Yaa-Zaa-|-(S,diacylglyceryl)Cys-, in which Xaa is hydrophobic (preferably Leu), and Yaa (Ala or Ser) and Zaa (Gly or Ala) have small, neutral side chains.</text>
            <dbReference type="EC" id="3.4.23.36"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Protein modification; lipoprotein biosynthesis (signal peptide cleavage).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase A8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.23.36" evidence="6"/>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00665"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00161">
        <property type="entry name" value="LspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001872">
        <property type="entry name" value="Peptidase_A8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33695">
        <property type="entry name" value="PTHR33695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01252">
        <property type="entry name" value="Peptidase_A8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="2 6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="100"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="179"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="150"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD88173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="218" mass="24634" checksum="64E0E7BD9EBA608B" modified="2019-11-13" version="1">MSLKKATILIFVILLIDQISKFYIKTHFALHDKIVVFNWFQILFVENEGMAWGTKISDFIPGISDRTAKVCLTVFRIFAVFGIGYWLVRSVKNQSSRILIFAIALILAGALGNIIDSAFYGIIFDSSQGQIATFLPAHGYDTLFHGKVVDMLHFPMWSGFLPEWIPLFGGKYFTFFEPVFNVADMAISSGIGILIFFNRKAFQEDEEEAVKQPNVAPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG48</accession>
    <name>A0A5C6ZG48_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Restriction endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_11830</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025745">
        <property type="entry name" value="Mrr-like_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007560">
        <property type="entry name" value="Restrct_endonuc_IV_Mrr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04471">
        <property type="entry name" value="Mrr_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14338">
        <property type="entry name" value="Mrr_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mrr_N" evidence="2">
        <location>
            <begin position="9"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="Mrr_cat" evidence="1">
        <location>
            <begin position="127"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="268" mass="30495" checksum="39DDCFA800E91EB6" modified="2019-11-13" version="1">MKSFPKREYFFNYTIQALTELGGSGSNDEINNKVIDILQLPEELLNKMHKNTNQTEFEYQMAWVRTMLKNQGSIENSKRGVWAIKANQEINLPKYKIAFDKSLAKKIDEEITDDEEWRQKLLNVISDNLSPNAFERLVQRILREKGFSQVEVKGRTGDGGIDGVGIAKINGILSFHIIFQCKRYKGKVGAKDMRDFRGAMVGRTDKGLFITTGMFTRDAIAEASRDGAPVIDLIDGDLLVEKLKELGLGVSVEFKEEVTIDEDWFKNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG67</accession>
    <name>A0A5C6ZG67_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Tyrosine--tRNA ligase</fullName>
            <ecNumber evidence="7">6.1.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Tyrosyl-tRNA synthetase</fullName>
            <shortName evidence="7">TyrRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">tyrS</name>
        <name evidence="9" type="ORF">ESY86_13975</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + L-tyrosine + tRNA(Tyr) = AMP + diphosphate + H(+) + L-tyrosyl-tRNA(Tyr)</text>
            <dbReference type="Rhea" id="RHEA:10220"/>
            <dbReference type="Rhea" id="RHEA-COMP:9706"/>
            <dbReference type="Rhea" id="RHEA-COMP:9707"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78536"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.1" evidence="7"/>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004831">
        <property type="term" value="F:tyrosine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006437">
        <property type="term" value="P:tyrosyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00805">
        <property type="entry name" value="TyrRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02006">
        <property type="entry name" value="Tyr_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002307">
        <property type="entry name" value="Tyr-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024088">
        <property type="entry name" value="Tyr-tRNA-ligase_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024107">
        <property type="entry name" value="Tyr-tRNA-ligase_bac_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11766">
        <property type="entry name" value="PTHR11766"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01040">
        <property type="entry name" value="TRNASYNTHTYR"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00234">
        <property type="entry name" value="tyrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="short sequence motif" description="'HIGH' region" evidence="7">
        <location>
            <begin position="39"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="7">
        <location>
            <begin position="238"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>L-tyrosine</name>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>L-tyrosine</name>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>L-tyrosine</name>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD88203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="434" mass="49057" checksum="9B2EEBED8A8DA240" modified="2019-11-13" version="1">MNTNFVEELRWRGMLHDIMPGTEEQLNKEMTTAYIGFDPTSDALHIGSLVPIILLVHLEKAGHKPIALVGGATGMIGDPSGKSDERNLLDEKTLNHNVAGIKAILSRFLNFDGTTENAPVLVNNYDWMKDFSFIDFARDVGKRITVNYMMSKDSVKKRLSGEEGNIGMSFTEFTYQLIQGYDFYHLYKHHNCVLQMGGSDQWGNITTGTELVRRMHVGEEAKAYAMTCPLITKADGSKFGKTEGGNIWLTADKTSVYKFYQFWLNASDADAEKYIKIFTFLDRDSIESFIATHNENPHLRLLQKRLAQEVTTFVHSQEEFENAEKASQILFSKSFKADIKTLDEQTFLDVFEGVPLVEISRETFSSLDMIGALAAETNFLGSNSEARRALKENAVSVNKEKVTEDYQLSEDDLINNKYIILNKGKKHTYIIKVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGA3</accession>
    <name>A0A5C6ZGA3_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">50S ribosomal subunit assembly factor BipA</fullName>
            <ecNumber evidence="2">3.6.5.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">GTP-binding protein BipA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">typA</name>
        <name evidence="2" type="synonym">bipA</name>
        <name evidence="4" type="ORF">ESY86_10105</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>GTP + H2O = GDP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="2">Binds to ribosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.-" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03710">
        <property type="entry name" value="BipA_TypA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00849">
        <property type="entry name" value="BipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035651">
        <property type="entry name" value="BipA_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042116">
        <property type="entry name" value="TypA/BipA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006298">
        <property type="entry name" value="TypA_GTP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908:SF8">
        <property type="entry name" value="PTHR42908:SF8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01394">
        <property type="entry name" value="TypA_BipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="2" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Tr-type G" evidence="3">
        <location>
            <begin position="2"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="14"/>
            <end position="19"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="127"/>
            <end position="130"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="599" mass="67217" checksum="7DAF4D4F1212B891" modified="2019-11-13" version="1">MTKIKNIAIIAHVDHGKTTLVDKIMYHCHLFRDNENTGDLILDNNDLERERGITITSKNVSVIYKDTKINIIDTPGHADFGGEVERVLNMADGVLLLVDAFEGPMPQTRFVLQKALDLGLKPCVVINKVDKENCTPEEVHEKVFDLMFELGAEEWQLDFPTVYGSAKNNWMSDDWKNETENIEPLLDMVIEHIPTPVFKEGTTQMLITSLDFSSFTGRIAIGRVQRGNVVEGQQISLVKRDGSVTKSRIKEVFIFEGLGRKKVQSVETGDICAIIGIEGFEIGDTICDLDNPEGLKAIAIDEPTMSMLFTINDSPFFGKDGKFVTSRHIKDRLEKELEKNLALRLGETGSADKFMVYGRGVLHLSVLIETMRREGYELQIGQPQVIIKEIDGVKCEPIEELTIDLPESVSGRAVEFVTMRRGEMLSMVAKGERMVCEFLIPSRGIIGLRNQLLTATAGEAIMAHRFKEYQPIKGAIPGRISGSLVSMENGVAIPYSIDKLQDRGKFFVEPGENIYEGQVIGENSRQDDMAVNITKAKKQSNVRSSGADDKAKIVPAIKFSLEEALEYIQKDEYVEVTPKHIRLRKIYLTEVDRKRFKNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGA4</accession>
    <name>A0A5C6ZGA4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_13485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="35"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="124" mass="14161" checksum="77D7574DFC3FCCEB" modified="2019-11-13" version="1">MKFPQNNIIDNWLNENGNPEIARLVEKNLALTEKINSILKERDIKKGEFAEMLGKKPSEVSKWLSGTHNLTMKSINKMEFVLGVDLINIEPITEVKYVYLGLIQGGEIENAMNDYEDSNYNIAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGN5</accession>
    <name>A0A5C6ZGN5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fibronectin type III domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_09555</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="SSF49265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fibronectin type-III" evidence="1">
        <location>
            <begin position="31"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="218" mass="24169" checksum="E61CC012E7F5B4A8" modified="2019-11-13" version="1">MKKILFVLAIILCYGCEDIIGVEDISNTLVIPLAPSNEAVLTEDSVVFSWDAVAEAEGYRIQVARPNFENATQIVVDSLVGSTSFLQVLASGDYEWRIRAENSDYQSTYTTYSFTINSINDDISSDQVQLLAPAEGLSFTETEIINFSWEALPGANGYTIQIASPNFESAIEIVEDVNLTATSFSVSNLDANTYEWRVRAKNSEYQTAYTTQTFTVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH33</accession>
    <name>A0A5C6ZH33_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_13885</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="219" mass="24835" checksum="9C6036B94BA15DDB" modified="2019-11-13" version="1">MLKKLACVLALVSILGCKQDQKLPNNFDYGSISNGVYTNAYFDMRFAFDDSWNVQTPEEMNDIANLGTELITNEGTKQAVKANEINTANLFAAYRYEMEAAVAYNYSIIIVAENTNMYPKVKRGRDYLDEAKKMMQQTVVNYTFEDDYSSKNIGGKDFDVMTVSGNYMDASFSQKYMTTIYRGFSVSIIISYDSNEQLQTLENLIDQIAFTEGSSKNKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH52</accession>
    <name>A0A5C6ZH52_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">T9SS type A sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_13990</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023149647" evidence="1">
        <location>
            <begin position="23"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="Por_Secre_tail" evidence="2">
        <location>
            <begin position="41"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="111" mass="12384" checksum="EE7A569B1B2480C8" modified="2019-11-13" version="1">MKNYVFIIFFTFTLGFSSIGFAQSSDLQQSPKTETIEGLSIYPNPVSNGKLYITTKSNLIKSVDIFDVLGKRIVSTSLFGKELNISKLTPGVYIIKIEENNVTATRKLVVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHA8</accession>
    <name>A0A5C6ZHA8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta</fullName>
            <shortName evidence="1">ACCase subunit beta</shortName>
            <shortName evidence="1">Acetyl-CoA carboxylase carboxyltransferase subunit beta</shortName>
            <ecNumber evidence="1">2.1.3.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">accD</name>
        <name evidence="4" type="ORF">ESY86_09990</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetyl-CoA + N(6)-carboxybiotinyl-L-lysyl-[protein] = malonyl-CoA + N(6)-biotinyl-L-lysyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:54728"/>
            <dbReference type="Rhea" id="RHEA-COMP:10505"/>
            <dbReference type="Rhea" id="RHEA-COMP:10506"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:83144"/>
            <dbReference type="ChEBI" id="CHEBI:83145"/>
            <dbReference type="EC" id="2.1.3.15"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the AccD/PCCB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.15" evidence="1"/>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00655">
        <property type="reaction ID" value="UER00711"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009317">
        <property type="term" value="C:acetyl-CoA carboxylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016743">
        <property type="term" value="F:carboxyl- or carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001295">
        <property type="term" value="P:malonyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01395">
        <property type="entry name" value="AcetylCoA_CT_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034733">
        <property type="entry name" value="AcCoA_carboxyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000438">
        <property type="entry name" value="Acetyl_CoA_COase_Trfase_b_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011762">
        <property type="entry name" value="COA_CT_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01039">
        <property type="entry name" value="Carboxyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01070">
        <property type="entry name" value="ACCCTRFRASEB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00515">
        <property type="entry name" value="accD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50980">
        <property type="entry name" value="COA_CT_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="1" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="1" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CoA carboxyltransferase N-terminal" evidence="3">
        <location>
            <begin position="24"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="285" mass="31621" checksum="7B7E95C3F58BB520" modified="2019-11-13" version="1">MSWFKRKEKGITTTTSEKKDTPKGLWYKSPTGKIIDTDELEANFYVSPEDDYHVRIGSNEYFEMLFDENKFKEFDANLTSKDPLNFEDTKKYPDRLKAAQEKTKLKDAVRTAVGKSKGRDLVVACMDFAFIGGSMGSVVGEKITRAADYALKNEIPFMIISKSGGARMMEAALSLMQLAKTSVKLAQLADAGIPYISLCTDPTTGGTTASFAMLGDINISEPGALIGFAGPRVVKDTTGQDLPDGFQTSEFLLEHGFLDFITHRKHLKDKVNLYLDLITNQPVRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHC9</accession>
    <name>A0A5C6ZHC9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07235</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="318" mass="35983" checksum="0A00C130D6121E4B" modified="2019-11-13" version="1">MSKILIIGAAGQIGSELTYKLRELHGDDNVIASDITYENTALVNSGIFEIVDAQDQASVRICVDKHKIDTIYLMAAMLSATGEKYPMKAWDLNMNSLFHVLNLAKEGIIKKVFWPSSIAVFGPTTPKVDTPQHSIMEPSTVYGITKQAGERWCDYYHKNYGVDVRSLRFPGIISWKTMPGGGTTDYAVEIYHQAILDKSYECFLKEDTELPMMFMDDAINAMVELMDAASETVKIRSSYNLAAISITPKEVSEAIKKHIPDFRISYSPDFRQKIADTWPKSIDDSEARTDWGWNQKFDLDKMTEEMLKNLSEKYAKVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHD3</accession>
    <name>A0A5C6ZHD3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07265</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022689268" evidence="1">
        <location>
            <begin position="22"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="190" mass="21948" checksum="78C5C6551BE0B24B" modified="2019-11-13" version="1">MKTVKQVLAVVFMLTIVTGYANDVKNEPTSSSATFRFLNVKKGHQVSIKNDEGRVIHRETVKRNGDYAKRFDLSDLEDGNYTIELDKDFEIIIKPFKMVSNEVILLSKLQTSIFKPVVRTKKNHLMISKLALNNESLNIELYYNDELIHKDELKGAKILERIYTLSPSEEGIYVLRMSSGDRTFVERFRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHE9</accession>
    <name>A0A5C6ZHE9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Very short patch repair endonuclease</fullName>
            <ecNumber evidence="5">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_08495</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">May nick specific sequences that contain T:G mispairs resulting from m5C-deamination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the vsr family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="5"/>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00221">
        <property type="entry name" value="Vsr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004603">
        <property type="entry name" value="DNA_mismatch_endonuc_vsr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03852">
        <property type="entry name" value="Vsr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018267">
        <property type="entry name" value="VSR_endonuc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00632">
        <property type="entry name" value="vsr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4 5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR018267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD89413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="157" mass="18885" checksum="21068A0AB5F0020E" modified="2019-11-13" version="1">MAIYDEPKIIVPKFNEESGFYTTKKRSKIMGKIRGKNTKPELLFRKALWKKGIRYRINSKTIIGRPDVSIKKYKLAIFIDGEFWHGHDWETRKNRIKSNRGFWIPKIERNMQRDREVNMRLEDLDYTVFRFWETEIRTNLNTCVNDVMVFLDTGGFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHH3</accession>
    <name>A0A5C6ZHH3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">YjgP/YjgQ family permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_11395</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005495">
        <property type="entry name" value="LptG/LptF_permease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33529">
        <property type="entry name" value="PTHR33529"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03739">
        <property type="entry name" value="LptF_LptG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="56"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="102"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="371"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="398"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="429"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="526"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="550"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="594"/>
            <end position="611"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD88835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="623" mass="70827" checksum="9A00CC6E26C81D12" modified="2019-11-13" version="1">MKILDRYILTTYLKTFLSVFLILMFIFVLQAIWLYIGDLAGKDLDSYVIVKLLLYITPTLIPLILPLTILLVSIMVFGSFAENYEFAAMKSTGISLQRAMRGLSFFIVLLGIVTFVFSNNVIPWANYNVYNLRKNIAQVKPALAISEGQFNEIGTYNIKVDKKTGENDEFLETVVIHEKSGRSTANRKIIIAKRGELKSNENSPILQLVLYEGNRYEEIFSNQNPKQNKKRPHAKSYFDEYTINVDIEGLNDVDIDDKSYDNRYNMLDVSALNFTIDSLQEKKVETLKNFSNTLYRRTAITSLPLNIKPKKDSLYTGAILDLFNDKTKIQLLNLASNSISSTKQIVSSNKQSITGNTKWMNKHIVALHEKYVLGIACIILFFVGAPLGALIRKGGIGLPLVIAILLFLSYHFIGIFAKNSSLDGTFSSVIATWLSTAIMLPLSIFLTTRATKDRGLLEFDHIIEPIKKLLKIKPKAEKEASNARKSTLDDTIIENLNLIGHEDRVKIKDSAAFETKLVDYKFNAKCTMVFYCIAIPLLVFHFIFKNNKLPAMASASLELFTIAGVILLIYFMLATRNLHQMYHYLEAKKLSKNPIWWVLGFVFYPLAFYIRRNKVSDDFSLDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHJ7</accession>
    <name>A0A5C6ZHJ7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_13655</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="SSF47473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="75" mass="8481" checksum="8B54E67BDB2D5F6A" modified="2019-11-13" version="1">MKSINLQITDFEFNQLGLNKNTLTFSELIEIIGKKITKQTLEKSIKLADKSGLSKISMEEINDEIKAHRNAKSNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHL7</accession>
    <name>A0A5C6ZHL7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">4-hydroxyphenylpyruvate dioxygenase</fullName>
            <ecNumber evidence="7">1.13.11.27</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">hppD</name>
        <name evidence="7" type="ORF">ESY86_08600</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="5">Binds 1 Fe cation per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the 4HPPD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.27" evidence="7"/>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003868">
        <property type="term" value="F:4-hydroxyphenylpyruvate dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009072">
        <property type="term" value="P:aromatic amino acid family metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07250">
        <property type="entry name" value="HPPD_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08342">
        <property type="entry name" value="HPPD_N_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005956">
        <property type="entry name" value="4OHPhenylPyrv_dOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041735">
        <property type="entry name" value="4OHPhenylPyrv_dOase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041736">
        <property type="entry name" value="4OHPhenylPyrv_dOase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11959">
        <property type="entry name" value="PTHR11959"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009283">
        <property type="entry name" value="HPP_dOase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01263">
        <property type="entry name" value="4HPPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="4 5" id="KW-0408">Iron</keyword>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="VOC" evidence="6">
        <location>
            <begin position="27"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="VOC" evidence="6">
        <location>
            <begin position="184"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="354"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR009283-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD89433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="386" mass="44138" checksum="ABC3B18188D6038D" modified="2019-11-13" version="1">MAKEVKNVEYGLEKIFDKAQDFLPLLGTDYVEFYVGNAKQAAHFYKTAFGFQSYAYRGLETGSKDSVSYVLKQDKIRLVLTTPLSSKSPINDHIVKHGDGVKVIALWVDDARKSYEETTKRGAKSYLEPVVEKDEHGEVVRAGIYTYGETVHMFVERKNYKGKFLPGFRAWESDYNPEPVGLKFIDHMVGNVGWGQMNVWVKWYEDVMGFVNFLSFDDKQIHTEYSALMSKVMSNGNGRIKFPINEPAKAAKKSQIEEYLDFYEDSGVQHIAVATDDIIKTVAQLKARGIEFLPPPPQSYYDMIPERLGEHREMMTEDIGRLQELSIMVDADEEGYLLQIFTKPVEDRPTLFFEIIQRMGAKGFGAGNFKALFESIEREQEKRGTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHM5</accession>
    <name>A0A5C6ZHM5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AbrB/MazE/SpoVT family DNA-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007159">
        <property type="entry name" value="SpoVT-AbrB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037914">
        <property type="entry name" value="SpoVT-AbrB_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00966">
        <property type="entry name" value="SpoVT_AbrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89447">
        <property type="entry name" value="SSF89447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SpoVT-AbrB" evidence="1">
        <location>
            <begin position="6"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="81" mass="9693" checksum="C77A7E208F637578" modified="2019-11-13" version="1">METAIIKIGTSKGLRLSKTILETYNITDKVEMILEKDRIILKPIDSPRKNWEKAFEKMRKNNDDQLLFNDVFEDEDFEEWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHP8</accession>
    <name>A0A5C6ZHP8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF2237 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_10640</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018714">
        <property type="entry name" value="DUF2237"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37466">
        <property type="entry name" value="PTHR37466"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09996">
        <property type="entry name" value="DUF2237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="123" mass="13563" checksum="458479DBABFA75C2" modified="2019-11-13" version="1">MTTKKQTLNVLGEPLENCSCDPMTGYLRDGFCNTTPDDFGTHVVCAIVTEAFLEYSLSKGNDLITPVPQWNFPGLKPGDKWCLCVSRWKQAEKANVAPPVDLKATHALALKFVSLELLKAYSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHQ7</accession>
    <name>A0A5C6ZHQ7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Beta-ketoacyl-[acyl-carrier-protein] synthase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_13095</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00834">
        <property type="entry name" value="KAS_I_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000794">
        <property type="entry name" value="Beta-ketoacyl_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712">
        <property type="entry name" value="PTHR11712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_KS" evidence="3">
        <location>
            <begin position="6"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="425" mass="44866" checksum="B6D95CAC497DF008" modified="2019-11-13" version="1">MNKNRVVITGLGVVAPNGVGLDAFSEAIKTGTSGITFHQKLKDLNFSCCIGGIPQISEEKKLEYLSPLQLRGFNSAGILYGCMAGIDAWKDAGFEVDANSDLDTDTGLIFGAGTSGIEKFREAILKVDKGQVKRMGSTVVVQTMASGISAFLGGILGLGNQVTTNSSACTTGTEAILMGYERIKNGQAKRMLVGSCSDDGPYIWGGFDAMRVMTYKHNDSPEAGSRPMSATASGFVPGSGAGAFVLESLESALERNASIYAEVLGGNVNSGGQRNGGTMTAPNAEAVQRCITDALKNAKIAAQDIDAINGHLTATSKDSLEIANWTQALGRSGNDFPYINCLKSMVGHCLPAAGSIECVAAVLQLKEQFVFPNINCEDIHPEILELISEEKIVRELLKTKLEIVAKASFGFGDVNGCVIFKSYSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHS7</accession>
    <name>A0A5C6ZHS7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF479 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_11465</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008770">
        <property type="term" value="F:[acyl-carrier-protein] phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007431">
        <property type="entry name" value="ACP_PD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38764">
        <property type="entry name" value="PTHR38764"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04336">
        <property type="entry name" value="ACP_PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF011489">
        <property type="entry name" value="DUF479"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="1" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="2" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="199" mass="23771" checksum="1260432FD66A5481" modified="2019-11-13" version="1">MNFLAHIYLSGEHEAITIGNFIADGIRGKHYTKYPINLQKGILLHRQIDTFTDAHPTVRLSTKKLHKNYSHYSGVIVDILYDHFLAKNWHRYSNVPLELYIERFYDSLEDHYELLPARIQKMMPYMIADNWLLSYAKIEGIQKVLNGMNRRTKNISGMNHATNELKEFYTEFEREFTSFFEELRDFSQQKLLEIERKFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHU7</accession>
    <name>A0A5C6ZHU7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_14135</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044260">
        <property type="term" value="P:cellular macromolecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043412">
        <property type="term" value="P:macromolecule modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044238">
        <property type="term" value="P:primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="5"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="222" mass="25031" checksum="73441E4109B6916B" modified="2019-11-13" version="1">MKNIYILMVDDHPIIIEGYQNTLMATKNEDQTLIIDTANNCDAANVLLQKAAAEKPYDICFFDISLPPSADGEIKSGEDLAMICRDLMPNTKVVVLTMFNESYRIYSIVKDIKPDGFLIKSDLTSMELAEAFQVILTNPPYYSTTVNNVLKTSVIDKTYIDEHNRKILFLLSQGVKTKNLVEHLDLSLSAIEKRKKQLKMLFSVSDARDETLIEAARAKGFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHZ4</accession>
    <name>A0A5C6ZHZ4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="10">M13 family metallopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ESY86_07225</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08662">
        <property type="entry name" value="M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1380.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000718">
        <property type="entry name" value="Peptidase_M13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018497">
        <property type="entry name" value="Peptidase_M13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042089">
        <property type="entry name" value="Peptidase_M13_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008753">
        <property type="entry name" value="Peptidase_M13_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11733">
        <property type="entry name" value="PTHR11733"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01431">
        <property type="entry name" value="Peptidase_M13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05649">
        <property type="entry name" value="Peptidase_M13_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00786">
        <property type="entry name" value="NEPRILYSIN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51885">
        <property type="entry name" value="NEPRILYSIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase_M13_N" evidence="9">
        <location>
            <begin position="50"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M13" evidence="8">
        <location>
            <begin position="482"/>
            <end position="684"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD89570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="687" mass="77328" checksum="36B9EB79B6F071E2" modified="2019-11-13" version="1">MNTKISTIFMVSVIGISSFTGCKDDSKKDTAMAEQTPGIELESMDTSVDPKDDFYNYVNGNWIKNNEIPEDETRWGGFNVLRKSTRQDVLDIVNTAKELNKYEDGSDQKKALLVYQTELDTVARNEAGIKPIEPLLSKIDGINTLKDLQTVIAQNNGISAPFVGIGANADLNDSSTNIAWVYPGGLGLQRDYYLDMDSKSKEIRGQYLAHVSRMLQFINYSKADADAAAKRIMEMETQLAEPRLDKVAMRDARNYNNMSAVSDLDKMTPAIDWSKMISDLGIKSEIDTLNIMQPKYMAALNSFLKNTSIKDLKSLVDWSTLNRASGYLTTEIEMANWDFYAKTLTGAKKMKPADERALGTVDGSVGEAIGKLYVEAKFPPEAKEKAEKMIANIITAFQNRIEKLDWMTNDTKKKAIEKLNKFTVKIAYPDEWEDYSELEVKEGNSFADNMMAVINWSSRKNLDEIGQPVDRTEWGMAPQTVNAYFNPSNNEIVFPAAILQPPFYNYKADEAVNYGGIGAVIGHEISHAFDDSGARYDAEGNLKNWWTDEDLEKFTTRANALADQYSAIEVMDSLYINGKFTLGENIGDLGGVLGAYDGLQLFYENNERPGEIDGFTPEQRFFMSWATVWRTLTREDALRTQIKTDPHSPGIYRATQPLKNVDAFYEAFNIKEGDSMYIAPEDRVRIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHZ8</accession>
    <name>A0A5C6ZHZ8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Molybdopterin molybdenumtransferase</fullName>
            <ecNumber evidence="7">2.10.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_13330</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenylyl-molybdopterin + H(+) + molybdate = AMP + H2O + Mo-molybdopterin</text>
            <dbReference type="Rhea" id="RHEA:35047"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:36264"/>
            <dbReference type="ChEBI" id="CHEBI:62727"/>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.10.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 7">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 7">Belongs to the MoeA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.10.1.1" evidence="7"/>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061599">
        <property type="term" value="F:molybdopterin molybdotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032324">
        <property type="term" value="P:molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00887">
        <property type="entry name" value="MoeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008284">
        <property type="entry name" value="MoCF_biosynth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038987">
        <property type="entry name" value="MoeA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005111">
        <property type="entry name" value="MoeA_C_domain_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036688">
        <property type="entry name" value="MoeA_C_domain_IV_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005110">
        <property type="entry name" value="MoeA_linker/N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036135">
        <property type="entry name" value="MoeA_linker/N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10192">
        <property type="entry name" value="PTHR10192"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03454">
        <property type="entry name" value="MoeA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03453">
        <property type="entry name" value="MoeA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00852">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="SSF53218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63867">
        <property type="entry name" value="SSF63867"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63882">
        <property type="entry name" value="SSF63882"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00177">
        <property type="entry name" value="molyb_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01079">
        <property type="entry name" value="MOCF_BIOSYNTHESIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="6 7" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MoCF_biosynth" evidence="8">
        <location>
            <begin position="170"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD88286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="388" mass="42767" checksum="B767DAAE41123306" modified="2019-11-13" version="1">MVTIEEAHKIIKDQKVKLKTETRKLSDCLGFSISEDINAPFDMPSFDNSAMDGYALCGISQEYKIVGEVAAGDKKEFELKEFEAVRIFTGAKVPKNTSAVMMQEKTSVAGNKLTLEQMPKEGQSIRRKGEELTQGQLVFEKGYSITPAGIGLIGSLGIQNVEVFRKPLINLITTGNELIEPGKPKAVGQIYESNSYALASACEQFGFKCGNKKQIEDDFEAIKSGIKKSLETADVLILSGGISVGDYDFVKQALEENGVEEQFYKVFQKPGKPLYFGRKEERFVFALPGNPASSLSCFYVYVLHFLYQLSGSEKRGLPRYAFLISHDFENRGDRPSFLKAKISNGEVEILDGQGSSMILSMAQGNALAFIDAETSLKKGEQVQCLLIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI06</accession>
    <name>A0A5C6ZI06_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="10">DEAD/DEAH box helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ESY86_10715</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6 10" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Q_MOTIF" evidence="9">
        <location>
            <begin position="3"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="35"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="230"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="5">
        <location>
            <begin position="3"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD88956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="445" mass="49495" checksum="C5C3C8C3315F8866" modified="2019-11-13" version="1">MSNQFSDLGIQEQFQQSLVDLNISVPTAIQKKTIPMVLNQKEDVVVLAKTGTGKTAAFGLPLLQLIDLEKDNIQALILAPTRELGQQIYVNLLAFASANPKITIVSLCGGTPVKPQIERLKSTTHIVVATPGRLVDLIERDAIQLNKLNYFVLDEADEMLSALKDEVDAILKVIPKSRRTLLFTATMSGTIKQLVQNYMSKHVVHLEADMETLGHLGIDHQYVVVEPIEKLEVLLHFLSSKAGERGIIFCKTKAAVNKLAKNLAINKFSSGAIHGSLTQGIRDRIMGQFREGHIDILVATDLAARGIDVKEVSYVVNYHLPDTYDAYVHRSGRTARAGAKGLSLTVLQQEEVADIADFEKELGIVFKTFKKADAQSIEENNGLLWARKIFKTKPNRDVSEDFKAKIKTIFHHLTKEELVDKLLTNYLAQNSIDNSKLETPKKRKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI64</accession>
    <name>A0A5C6ZI64_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF493 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_06695</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007454">
        <property type="entry name" value="UPF0250"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027471">
        <property type="entry name" value="YbeD-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04359">
        <property type="entry name" value="DUF493"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117991">
        <property type="entry name" value="SSF117991"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="97" mass="10906" checksum="BC90A190FCECBB66" modified="2019-11-13" version="1">MSTEKKTEAFYNKLRSQLYDTSSWPAEYLYKFIVPSDLSKIDQIENLFNNLGAVISTKESKKGTYTSVSVNVTMADPDAVIKKYKEVGDKIDGVISL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI90</accession>
    <name>A0A5C6ZI90_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8 13">Glutamyl-tRNA reductase</fullName>
            <shortName evidence="8">GluTR</shortName>
            <ecNumber evidence="4 8 13">1.2.1.70</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 17" type="primary">hemA</name>
        <name evidence="17" type="ORF">ESY86_07490</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8 13">
            <text>(S)-4-amino-5-oxopentanoate + NADP(+) + tRNA(Glu) = H(+) + L-glutamyl-tRNA(Glu) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:12344"/>
            <dbReference type="Rhea" id="RHEA-COMP:9663"/>
            <dbReference type="Rhea" id="RHEA-COMP:9680"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57501"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="EC" id="1.2.1.70"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8 13">Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; 5-aminolevulinate from L-glutamyl-tRNA(Glu): step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="domain">
        <text evidence="8">Possesses an unusual extended V-shaped dimeric structure with each monomer consisting of three distinct domains arranged along a curved 'spinal' alpha-helix. The N-terminal catalytic domain specifically recognizes the glutamate moiety of the substrate. The second domain is the NADPH-binding domain, and the third C-terminal domain is responsible for dimerization.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="8">During catalysis, the active site Cys acts as a nucleophile attacking the alpha-carbonyl group of tRNA-bound glutamate with the formation of a thioester intermediate between enzyme and glutamate, and the concomitant release of tRNA(Glu). The thioester intermediate is finally reduced by direct hydride transfer from NADPH, to form the product GSA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8 13">Belongs to the glutamyl-tRNA reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.70" evidence="4 8 13"/>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00316"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008883">
        <property type="term" value="F:glutamyl-tRNA reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006782">
        <property type="term" value="P:protoporphyrinogen IX biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00087">
        <property type="entry name" value="Glu_tRNA_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000343">
        <property type="entry name" value="4pyrrol_synth_GluRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015896">
        <property type="entry name" value="4pyrrol_synth_GluRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015895">
        <property type="entry name" value="4pyrrol_synth_GluRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018214">
        <property type="entry name" value="GluRdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036453">
        <property type="entry name" value="GluRdtase_dimer_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036343">
        <property type="entry name" value="GluRdtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006151">
        <property type="entry name" value="Shikm_DH/Glu-tRNA_Rdtase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00745">
        <property type="entry name" value="GlutR_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05201">
        <property type="entry name" value="GlutR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01488">
        <property type="entry name" value="Shikimate_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000445">
        <property type="entry name" value="4pyrrol_synth_GluRdtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69075">
        <property type="entry name" value="SSF69075"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69742">
        <property type="entry name" value="SSF69742"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01035">
        <property type="entry name" value="hemA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00747">
        <property type="entry name" value="GLUTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 11" id="KW-0521">NADP</keyword>
    <keyword evidence="6 8 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7 8 13" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GlutR_N" evidence="16">
        <location>
            <begin position="15"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="Shikimate_DH" evidence="15">
        <location>
            <begin position="181"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="GlutR_dimer" evidence="14">
        <location>
            <begin position="320"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8 10">
        <location>
            <begin position="57"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8 10">
        <location>
            <begin position="118"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8 9">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 11">
        <location>
            <begin position="193"/>
            <end position="198"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for activity" evidence="8 12">
        <location>
            <position position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000445-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000445-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000445-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000445-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF01488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF05201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="TXD89620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="420" mass="46823" checksum="5169053951F6AA8D" modified="2019-11-13" version="1">MEHYTRSKGTTFYAIGLSYKKADAEVRGHFSLDETAKLAVLNQAKASGIESLIITSTCNRTEIYGFAQHPFQLIQLLCDNTKGTVEEFQKVAHVYKNAEAISHIFRVGSGLDSQILGDFEIISQLKVSARLSKKMQLFNPFLERLINAVIQASKRIKTETEISSGATSVSFASVRYIMNHIEAVSEKNILLFGTGKIGRNTCENLVKHTKNSHITLINRTKDKAEAIAGKFNLLVKDYSNLQEEINASDILIVATGAQNPTVDKHCIQTGKPLLILDLSIPKNVHSNVTELDNVTLVHLDDLAKITDNTLEKRKAQIPVAEAIIEEIRLDFHAWLTTRKFAPTIKALKLKLNDFATAELDTQRKKMSDFNEVQATLISNNIIQKITNHFAHHLKGDDVSTDDSLELIKKVFQLEAAIDNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIB9</accession>
    <name>A0A5C6ZIB9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transport permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_09760</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ABC-2 integral membrane protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00164">
        <property type="entry name" value="ABC2TRNSPORT"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="129"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="165"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="255"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="7">
        <location>
            <begin position="35"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD89051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="287" mass="32904" checksum="0BBE2BE6F0D0A6EF" modified="2019-11-13" version="1">MNTIDKTHEYTLVIEPKTKLLDFDLKELWRYRDLLLLFVRRDFVSVYKQTIFGPLWFFIQPILTTIMFMVVFGGIAKMSTDGLPQAVFYLAGIVSWNYFAEALKTTSETFVTNAGIFGKVYFPRVITPLSIVVSKLLTFAVQFFLFLLVYFYYLWFTDATLEPNLMLLLLPVLIVITAGLALGLGLLITALTTKYRDFRFLIGFAVQLAMYATPIIYPLSEIDNEKLRFAVLANPMTSIIETFRYAFTGSGEFSWFNLGYSFVVMIVLLIVGTLSFNKVEKTFMDTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIC3</accession>
    <name>A0A5C6ZIC3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_08750</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="196" mass="21786" checksum="6341377C4201FA65" modified="2019-11-13" version="1">MKNLKHISKQLKTTIKVGVIVILLLSIVACDKDNEPNIDQTSFQPQSDQGNNLVLTYPDESKEYINGDAVFGWGKGQLLGDNYWKQVMGGSSERGFVVRINIPKGTPKDSIIGLELELDGARLYLQNSTEIPLRPELWIRGDGFDESVNAYGKIKIIETDSYDIIGEVTAGVTDTNGETVRISGFFWKKNADSWSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIF1</accession>
    <name>A0A5C6ZIF1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_11995</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="90"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="178" mass="20092" checksum="E005CDBA2F6C7A65" modified="2019-11-13" version="1">MGLEIITFIAAILFGIFIYWRESNGNGAYRLVNRMVNSKKLQMKPNSKKGFIFQQAFLPRLIFLVAVFLFAAVVIEFLTPLQVLVNYQGLSLFSSAIFGTLIGTYLASFIIKSTQAVGAQSDSLEDKFDVAVDRGRDFFDDLKHKDNNAVEQAKEDIKEEPDPNKKSARERLKDKGLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIQ4</accession>
    <name>A0A5C6ZIQ4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glucose-1-phosphate adenylyltransferase</fullName>
            <ecNumber evidence="7">2.7.7.27</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_11440</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.27" evidence="7"/>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008878">
        <property type="term" value="F:glucose-1-phosphate adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011831">
        <property type="entry name" value="ADP-Glc_PPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005836">
        <property type="entry name" value="ADP_Glu_pyroP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43523">
        <property type="entry name" value="PTHR43523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02091">
        <property type="entry name" value="glgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00808">
        <property type="entry name" value="ADP_GLC_PYROPHOSPH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00809">
        <property type="entry name" value="ADP_GLC_PYROPHOSPH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00810">
        <property type="entry name" value="ADP_GLC_PYROPHOSPH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2" id="KW-0321">Glycogen metabolism</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="6">
        <location>
            <begin position="8"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD88843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="421" mass="47390" checksum="C8D5C56243A9D4E2" modified="2019-11-13" version="1">MINDSVLAIILGGGQGSRLYPLTQKRSKPAVPIAGKYRLVDIPISNCINSDIKRMFVLTQFNSASLNRHIKNTYHFSFFSSAFVDVLAAEQTIGSEEWFQGTADAVRQSMHHFLSHDFEYALILSGDQLYQMDFNDMIERHKKSGAEISIATLPVNAKDATSFGILKTDDNSMISSFIEKPNTEALQGWESVVSEEMFKDGRHYLASMGIYIFNKDLLVKLMDEPDTVDFGKEIIPQSIDKYKTFSYQYEGYWTDIGNIDSFFEANLGLTDDIPQFNLYDSHKRIYTNARILPTSKITGTLLYKAVIADGCIIHADKIERSVIGIRSRIGKESVVINCYMMGSDDYESLKFIDDNNIEIYMGIGERCFIKNAILDKNSRIGDDVVIDGSKHHEDVETDSYVIRDQIVVVKKGATIASGTII</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIR2</accession>
    <name>A0A5C6ZIR2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">GxxExxY protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_05000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026350">
        <property type="entry name" value="GxxExxY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13366">
        <property type="entry name" value="PDDEXK_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04256">
        <property type="entry name" value="GxxExxY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="128" mass="14560" checksum="9825BAE38C714192" modified="2019-11-13" version="1">MEQKTENDISYLIRGAIFKIYNELGPGLLESVYETVLSFELRKQGLEAKNQVPLPVFYEGNKLGLGFRLDLLVNEKVVVEIKSVENLAEVHHKQVLTYLKLSNLKLGILVNFNVDNIEKGIFRKVNGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ23</accession>
    <name>A0A5C6ZJ23_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">GTP cyclohydrolase 1 type 2 homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_05840</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the GTP cyclohydrolase I type 2/NIF3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002678">
        <property type="entry name" value="DUF34/NIF3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017221">
        <property type="entry name" value="DUF34/NIF3_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036069">
        <property type="entry name" value="DUF34/NIF3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13799">
        <property type="entry name" value="PTHR13799"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01784">
        <property type="entry name" value="NIF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037489">
        <property type="entry name" value="UCP037489_NIF3_YqfO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102705">
        <property type="entry name" value="SSF102705"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00486">
        <property type="entry name" value="YbgI_SA1388"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR037489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD90258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="364" mass="39842" checksum="232572AC1FE86248" modified="2019-11-13" version="1">MKIQEVIDFLEELAPLDYAANFDNVGLLVGDKNQKLTGILVTLDTLEEVVDEAIAKNCNLIVSFHPIIFKGLKNLTGKDYVQRTVIKAIQHNIGIYAIHTALDNAYKGVNAIICDQLKLINKRILIPQQGTIKKLTVFVPSSNAKALRTALFESGAGNIGNYDACSFNSEGIGTYRGNEDSNPKIGKKGELYEAAETKISVTFNKHVEAKVLKSLLQAHPYEEIAYEVTTLENSNQHIGIGMVGELVQAQETRSFFKDLKSLMHVGCIRHSALTTENVKKIAVLGGSGSFAIAAAKAAGADVLITADLKYHDFFAAEGQIILADIGHYESEQFTKTFLVDYLSKKITNFAIVLSTTITNPVKYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ53</accession>
    <name>A0A5C6ZJ53_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Metal ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_07320</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="22"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="54"/>
            <end position="61"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD89589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="260" mass="28849" checksum="329218950A022994" modified="2019-11-13" version="1">MKSHNSDQHEKTVTAAETVFAVKVDDLTVAYNYKPVLWDIDLEIPEGVLMAIVGPNGAGKSTLIKSILGILKPIAGSVSIYGKPYKEQRSLVAYVPQKGSVDWDFPTTALDVVMMGTYGSLGWIKRPKQREKKLALEALEKVGMLSFKGRQISQLSGGQQQRIFLARALVQDASIYFMDEPFQGVDASTEIAIINILKALRKAGKTVVVVHHDLQTVPEYFDWVTFLNVKKIATGPVKDIFNDDNLTKTYGINYKVSIQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ90</accession>
    <name>A0A5C6ZJ90_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="144"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="203"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="328" mass="37263" checksum="93EF4D935130B382" modified="2019-11-13" version="1">MNKEQFTYLLQQPQHISVDQTTALHQLLATYPFVQSARALYLKGLMAKGSPQYNQELKVTAAYTTDRSVLFDYITSEVFNQNEISQRIKQNSEQLRDIEVNAHDDITVAKKVTIDDALKQQIANTEGVLDPELFEKKAGNIPESLASQKQSPQPTASKISDNNSPDAPEKTLKMGQPLEFDQNETHSFAEWLNITGFKPIERKAEELSSEESEPSTSEKEEVKDDEIPQKNSAAIDEKFKLIDKFLKNNPKIVPSKESPKIELVKNDHTSNDGLMTETLARIYLEQNNYEKAIQSYKVLSLKYPEKSGFFADQIKAVKQLQEHNPKNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ99</accession>
    <name>A0A5C6ZJ99_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SufE family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_08320</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SufE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003808">
        <property type="entry name" value="Fe-S_metab-assoc_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43597">
        <property type="entry name" value="PTHR43597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02657">
        <property type="entry name" value="SufE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SufE" evidence="2">
        <location>
            <begin position="12"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="140" mass="16097" checksum="79C88BD99AAA1119" modified="2019-11-13" version="1">MTITEIQNEIIDEFDMFEDWEERYQYMIDLGKSLPLIAEQYKTEDNIIKGCQSRVWVHADLEGDKVLFTADSDAIITKGIIAILIRTFSDQHPKAIIEANTDFIDKIGLKEHLSPTRANGLVSMIKQLKMYAIAYQTQLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJB4</accession>
    <name>A0A5C6ZJB4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GTP cyclohydrolase 1</fullName>
            <ecNumber evidence="5">3.5.4.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">GTP cyclohydrolase I</fullName>
            <shortName evidence="5">GTP-CH-I</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">folE</name>
        <name evidence="7" type="ORF">ESY86_04580</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>GTP + H2O = 7,8-dihydroneopterin 3'-triphosphate + formate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17473"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58462"/>
            <dbReference type="EC" id="3.5.4.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homopolymer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the GTP cyclohydrolase I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.16" evidence="5"/>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00848">
        <property type="reaction ID" value="UER00151"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003934">
        <property type="term" value="F:GTP cyclohydrolase I activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035998">
        <property type="term" value="P:7,8-dihydroneopterin 3'-triphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.286.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00223">
        <property type="entry name" value="FolE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043134">
        <property type="entry name" value="GTP-CH-I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001474">
        <property type="entry name" value="GTP_CycHdrlase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018234">
        <property type="entry name" value="GTP_CycHdrlase_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020602">
        <property type="entry name" value="GTP_CycHdrlase_I_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11109">
        <property type="entry name" value="PTHR11109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01227">
        <property type="entry name" value="GTP_cyclohydroI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00063">
        <property type="entry name" value="folE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00859">
        <property type="entry name" value="GTP_CYCLOHYDROL_1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00860">
        <property type="entry name" value="GTP_CYCLOHYDROL_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 5" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="GTP_cyclohydroI" evidence="6">
        <location>
            <begin position="42"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD90036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="225" mass="25436" checksum="97FB040637C1521D" modified="2019-11-13" version="1">MSIEKNIEELDLLGNDHIGTSADTPLRENAFELSDSEKIKIIRKDVHHILETLGLDLNDDSLKGTPNRVAKMFVNEIFSGLHPNNKPSASTFDNKYKYGEMLVEKNINLYSTCEHHLLPIVGKAHIAYISSGKVVGLSKMNRIVDYFAKRPQVQERLTIQIVKELQQVLKTEDVACVIDAKHLCVNSRGIRDVDSSTVTSEFGGQFKNKDTKREFLDYIKLDTAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJS0</accession>
    <name>A0A5C6ZJS0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">RHS repeat-associated core domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_09610</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022385">
        <property type="entry name" value="Rhs_assc_core"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03696">
        <property type="entry name" value="Rhs_assc_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1039" mass="115214" checksum="4479ABE29B497683" modified="2019-11-13" version="1">MEASISTISAINGQLNELGYQYKYDHRNRLVEKKIPGKGKAASWEEIVYNKLDQPILTRDPNLKLQSKWLFTKYDAFGRVAYTGFMSGTSSRAALQTAANGTAAQYVTKGAAAITVAGTALYYPNNASVYPTSGITELHTINYYDDYTFDRDDLTLPGIADGQPVINHNDANKPLTKGLATGGKVRVLGTSSWITTLTGYDVKGRPIYSVSKNSYLSTTETATSKLDFVGKVDRATATHSKTGHATITTVDTFTYDDSGRLLAQKQKLDNILPEEFIVQNTYDALGQLTAKGIGGKTTQSRLQTVDYTYNIRGWLKNINDTDNLGSNLFGFRLNYNTASHGGTALFNGNIAETEWKTQSDNALRWYSYGYDALNRITVGTANSSNYDLTSVAYDKNGNIVNLLRKGHTAMDGNGIVTQYGTMDNLTYSYQPNSNKLMIVSDTGNDTFGFKDDHIGSGTDTSNDYTYDANGNMLKDLNKGIGTSTANGILYNHLNLPTQVKFNNSNTQKIDYFYDATGTKLEKVVTEGTNPVKRTKYAGNYVYEKTGSAADVLKFFSQPEGYVEPKIPGNYSLGFDYIYQYKDHLGNIRLSYMDAIGNYQNILDSDFETDFDGWVESGTVSYSRDNGRIKANVNAAWEGIRHNLTGIVTVAGETLKIKLDFDKGNTQSSVRLYLPEYDANNVLVRYNQLHSDLQTGYGDHTLTMQDSGNTIGSIRIDKDNTNTGIETYFYVGHVSLTFGELEIVEENNYYPFGLEHKGYNNIVSANSNSAASKYRYNGKEIQDELGLNMYDFGARNYDPALGRWMNIDPLAEQMRRHSPYNYAFNNPIYFIDPDGMAPLDWYQNIENSNYEYFEGSAEREGYTNIGASTDLAVGGGDNYSLNEDGSFQNNDTGESYKKGDELVVQESTGTEIISNLNTTEKASRFVSDIVAPFLELPQDIGAAIINQTNVVINEGFHEGTANDYDNVLIKNTYKFENWSFEKGRNTQSRGLSFEEGQEVINNTVSVVATPVKVVKNAVGNTVVKSAIKKGIKEALKRLED</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJS2</accession>
    <name>A0A5C6ZJS2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_05550</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="202" mass="22995" checksum="BE51FA88BF148F88" modified="2019-11-13" version="1">MKQIHLWFFSIYFLIFMVHQNYGQDIQMEIGLAIGKVNGKGHNLGKGEIHFNILKTYKFGQIGLDFSNGGNFIPGTRAIEEDNIETLSSSDSKFGAIAILFRLKIKKHFFIEPRFGYASLYSFVNTVDRNSISQDNITAGLGVGSKINRFTISLRYQYFGTTDNYEGFRNSTLIKSNSETLEIIFLRMSYSFGLDKLFKSKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJS8</accession>
    <name>A0A5C6ZJS8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptide-methionine (S)-S-oxide reductase</fullName>
            <ecNumber evidence="3">1.8.4.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_03610</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[thioredoxin]-disulfide + H2O + L-methionine = [thioredoxin]-dithiol + L-methionine (S)-S-oxide</text>
            <dbReference type="Rhea" id="RHEA:19993"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58772"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>[thioredoxin]-disulfide + H2O + L-methionyl-[protein] = [thioredoxin]-dithiol + L-methionyl-(S)-S-oxide-[protein]</text>
            <dbReference type="Rhea" id="RHEA:14217"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12315"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:44120"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.11" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008113">
        <property type="term" value="F:peptide-methionine (S)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002569">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036509">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01625">
        <property type="entry name" value="PMSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55068">
        <property type="entry name" value="SSF55068"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PMSR" evidence="5">
        <location>
            <begin position="6"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD90464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="167" mass="19000" checksum="F1221E08889E7D07" modified="2019-11-13" version="1">MKNLVKIAFGGGCHWCTEAVFQALKGVEKVEQGYVASVAGNSSFSEAVIVHFDEDVIKVEVLMEIHLLTHNSASNHAMRTKYRSAIYIFSEAQKFEVNLALNRIKANASEKIITSVLEFSAFEPSREAIQNYYQKNPSKPFCERYIAPKLKMLQQQFSEVYQIRTIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJW0</accession>
    <name>A0A5C6ZJW0_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Hydroxymethylbilane synthase</fullName>
            <ecNumber evidence="5">2.5.1.61</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">hemC</name>
        <name evidence="11" type="ORF">ESY86_07495</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H2O + 4 porphobilinogen = hydroxymethylbilane + 4 NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:13185"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57845"/>
            <dbReference type="ChEBI" id="CHEBI:58126"/>
            <dbReference type="EC" id="2.5.1.61"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>dipyrromethane</name>
            <dbReference type="ChEBI" id="CHEBI:60342"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the HMBS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.61" evidence="5"/>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004418">
        <property type="term" value="F:hydroxymethylbilane synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004852">
        <property type="term" value="F:uroporphyrinogen-III synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018160">
        <property type="term" value="P:peptidyl-pyrromethane cofactor linkage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006779">
        <property type="term" value="P:porphyrin-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06578">
        <property type="entry name" value="HemD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10090">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036108">
        <property type="entry name" value="4pyrrol_syn_uPrphyn_synt_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003754">
        <property type="entry name" value="4pyrrol_synth_uPrphyn_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000860">
        <property type="entry name" value="HemC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022419">
        <property type="entry name" value="Porphobilin_deaminase_cofac_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022417">
        <property type="entry name" value="Porphobilin_deaminase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022418">
        <property type="entry name" value="Porphobilinogen_deaminase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036803">
        <property type="entry name" value="Porphobilinogen_deaminase_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11557">
        <property type="entry name" value="PTHR11557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02602">
        <property type="entry name" value="HEM4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01379">
        <property type="entry name" value="Porphobil_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03900">
        <property type="entry name" value="Porphobil_deamC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00151">
        <property type="entry name" value="PORPHBDMNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54782">
        <property type="entry name" value="SSF54782"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69618">
        <property type="entry name" value="SSF69618"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00212">
        <property type="entry name" value="hemC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00533">
        <property type="entry name" value="PORPHOBILINOGEN_DEAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Porphobil_deam" evidence="8">
        <location>
            <begin position="5"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="Porphobil_deamC" evidence="10">
        <location>
            <begin position="221"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="HEM4" evidence="9">
        <location>
            <begin position="352"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD89621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="527" mass="59153" checksum="E194712C03F4A281" modified="2019-11-13" version="1">MPKLIRIGTRDSELALYQATTVQQQLETLGHRTQIVPIKSVGDLMLDRPINELGITGVFTKTLDLALINGDIDIAVHSFKDVPTVLPEQIVQAAVIKRGNHNDCLVFNDNEEFISQREAVVATGSLRRRAQWLNRYPTHTVVGLRGNVNLRLQKLEDSDWNAAIFAAAGLGRLDKTPENSFNLDWMLPAPAQGTIMVAALEADTETREICAEINHEETQICTSIERKFLNLLEGGCSAPIGALAYIKNEEVNFKGVLLSLDGSKKIEVERKEILGRHHNIAAYCANFIIDRGGKRLMDELKKASKEVNVYSTKTLSDEQKQHFHDDVISDSSDFVKINFNRMTQTVLRPFPKNVVLTSKNAVESLLNNFSAEELKFENIYCVGRRTKRLVERKIGKVKHTENSAKKLAEHLIEYIDGTEVTYFCSDIRLDELPNLLAENHIDVKEVIAYETKHDAQKIEDSVKGVMFYSPSTVQSFKKENVAADDMVAFCIGETTALEASKHFEDVRIAKMPSVESVIDLVNEHFGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJW1</accession>
    <name>A0A5C6ZJW1_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transport permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_05005</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ABC-2 integral membrane protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00164">
        <property type="entry name" value="ABC2TRNSPORT"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="171"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="222"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="250"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="285"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="340"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD90109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="368" mass="41645" checksum="B0544BF43EFD71B9" modified="2019-11-13" version="1">MKRFIGFIKKEFYHIFRDKRSLFILFGMPIAQILLFGFAITNEINNVDIAILDHSKDATTKEIINKIAASKYFSIKQMIEREADIASVFQKGHVKAVLNFERDFSKNLIKDRKATIQIITDATDPNTANTISNYVNAILQQYQKQLNKDITIAYQIVPQTRMVYNPELKSVYMFVPGVMTIILMLVSAMMTSISITREKELGTMEILLVSPLKPFQVIIGKVFPYIFLSIINAVVIVLLSIFIFKMPVQGSLFLLALESILFIISALALGILISTISATQQTAMMISLMGLMLPVILLSGFIFPISSMPMPLQIISHIIPAKWFIIIIKGIMLKGVGLEYLWKETVILLGMTVFFIALSVKKYKIRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJZ8</accession>
    <name>A0A5C6ZJZ8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_06680</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="130" mass="15343" checksum="9A6061B7CBC89A6D" modified="2019-11-13" version="1">MKKYIILVVFVLLQIGLYAQSQDKTYLRQGYSHDGNGYNVCELIIHSDSSYTFKKYKLENRKSRTEYRNYEPETAYGIIEKVGDFYEHTKIVNDSIPDKQWISQITNKKVILFTEKANGSLKRLEAYKRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK44</accession>
    <name>A0A5C6ZK44_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ferritin-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_06910</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010287">
        <property type="entry name" value="DUF892"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05974">
        <property type="entry name" value="DUF892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF892" evidence="2">
        <location>
            <begin position="3"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="39"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="161" mass="18451" checksum="582BFC13219E86A6" modified="2019-11-13" version="1">MKTLEDLFEHQLKDLYSAETQLIEAIPKMVKHAKDSKLKKAFEDHLEETKQQKTRLEEVCKALDIDPKGETCKAMEGLVKEAEGFIKEKKDDDVTNAGLIAEAQRIEHYEISGYGTAIRYAKELGHKEIAKKLKKTLDEEYGADDKLNKMAEQRLNREAID</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKK5</accession>
    <name>A0A5C6ZKK5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_05095</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="101" mass="11466" checksum="36AE4AB1C262A583" modified="2019-11-13" version="1">MKTKELAQTEKVSQKIQLVKGEFTPSEASDIIINLINEKINFHKLQRLQMWEGNHTCKTDELDGRIGELEKEKATAREFINSKRGSGQNLKINGILEITVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKL8</accession>
    <name>A0A5C6ZKL8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">50S ribosomal protein L31</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_03170</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the bacterial ribosomal protein bL31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.830.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034704">
        <property type="entry name" value="L28p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002150">
        <property type="entry name" value="Ribosomal_L31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042105">
        <property type="entry name" value="Ribosomal_L31_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33280">
        <property type="entry name" value="PTHR33280"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01197">
        <property type="entry name" value="Ribosomal_L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01249">
        <property type="entry name" value="RIBOSOMALL31"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143800">
        <property type="entry name" value="SSF143800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00105">
        <property type="entry name" value="L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01143">
        <property type="entry name" value="RIBOSOMAL_L31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD90382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="83" mass="9532" checksum="E4DACC6A6941F5A1" modified="2019-11-13" version="1">MKKGIHPENYRLIAFKDMSNEDVFLSKSTAETNETIDVDGVEYPVVKLEISRTSHPFYTGKSKLVDSAGRIDKFKNKYAKFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKN8</accession>
    <name>A0A5C6ZKN8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Radical SAM protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_09125</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="5">
        <location>
            <begin position="14"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD89209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="316" mass="35823" checksum="EF6BC9135510843A" modified="2019-11-13" version="1">MNQNFNHIQSVYWVFTQLCNDDCDHCYNDSSPFGKRISKDDCMAIIDNMPDKIDRIILSGGEPMADIKLLHAILDKIQARYKGETQIMLQTNGDLMKPKKLQVLIDKGVTRFDIASIDRYHKKAGGRLMELADIFESCGVNGTEKDPLLEGGHYLTENPLSWGYWGANEDMWLGGNWARGKALKHDNWLKDPDHNFCTILSGARNFLGGHEDIPQEISIQLWRINPCCPGTHFPMGDARKQKVADVLERASKSAVFKMLNDGDPLKMGESLGVTQEEASEKNQELKNICLYCDHFMKCHKDEIFDENGVKPSEQLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL75</accession>
    <name>A0A5C6ZL75_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Mechanosensitive ion channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_00445</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045275">
        <property type="entry name" value="MscS_archaea/bacteria_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30221">
        <property type="entry name" value="PTHR30221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD91098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="163" mass="18378" checksum="E9FEAED067F4590A" modified="2019-11-13" version="1">MDHTQIKLIETAVVIAVFVMILFVTNKFVDKTVSTHLLKKVRGKIIKKVINLITILICLVILLIIWGVDQSELVVFIGSVLTVLGIALFAQWSILSNITSSIIIFFNHPVKLDDTIKIVDKDFETEGRVSDIGVFFIILKTKEGEQITIPSNVFIQKMIKKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL89</accession>
    <name>A0A5C6ZL89_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_08460</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="112"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="294" mass="33147" checksum="B4666F989D8302F3" modified="2019-11-13" version="1">MIVNPQFFNYRLIIGSLIIAVAVLTVFSFTSYQSISAQQQFIEQEKNLIAGELSQMIDRYDDVSLSNNLIASNLALAKAKAKTTLDSLKMLRSDLSTLANFRQQLSHLRFKNKSLFASLDSVEQKNEELEKEKRLAYSSLDQKNHTISYLKNKNENLSKVLEKGALMTANSFKANGFQNIFGNRKVSTKAKQVNSFNVCFTLAENALTTKGLKNIYIQILNPKNNVIADKGVVKFGQHSLIYSQKEAVYYNNKVLELCIDVAAENNEQPLLEGTYNISVFQDHRKLGNAQVDLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL94</accession>
    <name>A0A5C6ZL94_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Site-specific DNA-methyltransferase (adenine-specific)</fullName>
            <ecNumber evidence="2">2.1.1.72</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_04385</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:15197"/>
            <dbReference type="Rhea" id="RHEA-COMP:12418"/>
            <dbReference type="Rhea" id="RHEA-COMP:12419"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90615"/>
            <dbReference type="ChEBI" id="CHEBI:90616"/>
            <dbReference type="EC" id="2.1.1.72"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.72" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022749">
        <property type="entry name" value="D12N6_MeTrfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003356">
        <property type="entry name" value="DNA_methylase_A-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004546">
        <property type="entry name" value="Restrct_endonuc_T1M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038333">
        <property type="entry name" value="T1MK-like_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12161">
        <property type="entry name" value="HsdM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02384">
        <property type="entry name" value="N6_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00497">
        <property type="entry name" value="hsdM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HsdM_N" evidence="5">
        <location>
            <begin position="13"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="N6_Mtase" evidence="4">
        <location>
            <begin position="161"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="474"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD90612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="507" mass="57845" checksum="4450DD02240F8476" modified="2019-11-13" version="1">MSNKLKPTQDQINAALWNACDTFRGAFDSSEYKNYILVFMFIKYLSDVWKDHYNALKEQYGDNEELIQRKLKRERFVLPPNCSFDFIFDHRNDTDIGEKIDKIFAQIEERNIEKLDGVFRNISFNSDKLGQTKDRNRRLKNLINDFAKPELDFRPSLWDDKEDILGEAYMYLLEKFASGAGKKGGEFFTPKEVSGLLAKLVSPKEGDRIFDPTCGSGSLLIKVAEETKDKEGNSTNNFAIYGQESNGDTWALSKMNCFLHKMDSAQIEWCDTINNPKLIEGDALMKFDIVVANPPFSLDKWGHENAEADRYKRFLRGVPPKSKGDYAFILHMIETTSPKGKVGVIVPHGVLFRGGAEQKIRQKLIEENLLEAVIGLPTNLFYGTGIPAAILIFNKAKTTKDILFIDASKGFEDGKKQNVLRTKDIDRIVATHKDFKTIEKFSTVVKPKEVAENDYNLNIPRYVDTFEEEAPVDIAEVQKNIVQLEAELVEVRAEMNKHLKELGFFPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL97</accession>
    <name>A0A5C6ZL97_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_06170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="161" mass="19240" checksum="475C6D42585666D5" modified="2019-11-13" version="1">MYLFIFTLLLVVFQYVNSKKVLEDYDQRLNRFMDTNEVYKDSIRNMNDREQPNIYSFNFDTNDDAMTYIENEGYVISEFIPFIKDQLMSLNIYEGAEHPLVPFASMTENKMLIDEIKLLNHKWIIASFTDGSYWGEMLLQYDITDRKELKFKVLDSVLYAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLD6</accession>
    <name>A0A5C6ZLD6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleotide pyrophosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_02450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11531">
        <property type="entry name" value="NTP-PPase_BsYpjD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012359">
        <property type="entry name" value="MazG-related_YpjD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004518">
        <property type="entry name" value="MazG_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42692:SF1">
        <property type="entry name" value="PTHR42692:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03819">
        <property type="entry name" value="MazG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029904">
        <property type="entry name" value="UCP029904_pph"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MazG" evidence="1">
        <location>
            <begin position="23"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="108" mass="12610" checksum="5367FB2AFA6CC417" modified="2019-11-13" version="1">MNIENSQKAVDHWIKEHGVRYFNELTNMAQLTEEVGEVARIIARRYGEQSEKESDKDKDLGEELADVVFVVLCLANQTGIDLQQAFDKKMDEKTKRDHDRHHNNKKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLK2</accession>
    <name>A0A5C6ZLK2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">GAF domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_02895</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="794" mass="92663" checksum="CACD6EF008134110" modified="2019-11-13" version="1">MKDINDSTELPFKLKISFDKLLQHYETLAKSDDQFLSKNASRILKIQEPIPILREGFTDIKYLKQYEQEINVILQESFSEVLTHNEIKTASVPFHSLRFNSSERFKKIIATAGTDFELEVLNLPENDKYILACTIILNAVYGYQLDFRRPFFYEIPDAKGIMRRYKILYNADFTEIIKTPEAPEITQEDYDMLLDNFGNMDLWREKFPPNSYVFKGFVVSNLFDTTNDAAISEIKSTLLVSGKRQSDNFIGDFQDTFRALFGVNDIEVGFVIYNKEDVTFERVIGKGIKSFLLFNSDVENCETALCHGSYDAILKDNRYFSISDVDKYFELTNGEAQFGSLHEQHIQSAIFAPIFGNNELLGVLELVSKTPKALNSINANKLEDVMPFIVMSVLRSKEEEANLIQAIIQQECTSIHPSVSWKFRDAARQFIKDKQELGNEAVFGEIVFKDIYPLFGQMDVKGSSDARNIATQKDLALQLNYVSKIFNAILNTEMLPIYEQMQFQMEAFSEELKTDFKVDTEQRVVNFLKNEIEPVLKFQSKKNKALQPEIDKYFNKIDKSLNLLYYYRKNYDDTIALINRNMTQLLDQKQQEAQKMYPHYFERYKTDGVEHNMYIGETITKMDSFNKVYLYNLRLWQLQVMCEMENNYYQNRNIYPMALDVASMILVFNQPLSIRFRMDEKQFDVDGTYNARYEVLKKRVDKAFIKGTEERVTKNGKITIVYSQKEDEQEYLQYVRFLQAKNLLDEKCEVFELENLQGVTGLKAISVDVLYHTDKADSDQKLYTYDDLIKQLDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLU6</accession>
    <name>A0A5C6ZLU6_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 9">tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase</fullName>
            <ecNumber evidence="8 9">2.8.4.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">(Dimethylallyl)adenosine tRNA methylthiotransferase MiaB</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">tRNA-i(6)A37 methylthiotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 13" type="primary">miaB</name>
        <name evidence="13" type="ORF">ESY86_05700</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>[sulfur carrier]-SH + AH2 + N(6)-dimethylallyladenosine(37) in tRNA + 2 S-adenosyl-L-methionine = 2-methylsulfanyl-N(6)-dimethylallyladenosine(37) in tRNA + 5'-deoxyadenosine + [sulfur carrier]-H + A + 2 H(+) + L-methionine + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:37067"/>
            <dbReference type="Rhea" id="RHEA-COMP:10375"/>
            <dbReference type="Rhea" id="RHEA-COMP:10376"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="ChEBI" id="CHEBI:74415"/>
            <dbReference type="ChEBI" id="CHEBI:74417"/>
            <dbReference type="EC" id="2.8.4.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="9">Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the methylthiotransferase family. MiaB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.4.3" evidence="8 9"/>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035596">
        <property type="term" value="F:methylthiotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01864">
        <property type="entry name" value="tRNA_metthiotr_MiaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005839">
        <property type="entry name" value="Methylthiotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020612">
        <property type="entry name" value="Methylthiotransferase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013848">
        <property type="entry name" value="Methylthiotransferase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038135">
        <property type="entry name" value="Methylthiotransferase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006463">
        <property type="entry name" value="MiaB_methiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01938">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00919">
        <property type="entry name" value="UPF0004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00273">
        <property type="entry name" value="(dimethylallyl)adenosine_tRNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01061">
        <property type="entry name" value="methylthiotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00089">
        <property type="entry name" value="TIGR00089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51449">
        <property type="entry name" value="MTTASE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01278">
        <property type="entry name" value="MTTASE_RADICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0408">Iron</keyword>
    <keyword evidence="7 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 9 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="MTTase N-terminal" evidence="11">
        <location>
            <begin position="29"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="12">
        <location>
            <begin position="169"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="domain" description="TRAM" evidence="10">
        <location>
            <begin position="418"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TXD90231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="481" mass="54742" checksum="E0555BB1AEFAF3F3" modified="2019-11-13" version="1">MQETTKEKPIDESKQGEQLVLEQKQGNTRKLYIESYGCAMNFSDSEIVASILLNQGYNTTPHLEDADLVLVNTCSIRDKAEQTVRKRLEKYNAVKRINPKMKVGVLGCMAERLKTKFLEEEKIVDLVVGPDAYKDLPNLLAEVDEGRDAINVILSKEETYGDISPVRLNSNGVTAYVSITRGCDNMCTFCVVPFTRGRERSRNPQSIIEEVNDLWDKGYKEITLLGQNVDSYLWYGGGLKKDFVKASDLQQATAVNFAALLELCAKAQPHMRIRFSTSNPQDMTLDVIETMAKFDNICKHIHLPVQSGSDRILKAMNRLHTREQYFELIDNIKRILPECSVSQDLISGFPTETEADHQDTLSLMDYVKYNFGYMFTYSERPGTTAERKFKDDVPEETKKRRLAEIVQRQREHSEIRTKEYLNSIVEVLIEKESKKSDAQWSGRTSQNIVAVFPKEHYKVGDLVKVKVMDCTSATLIGEIAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM14</accession>
    <name>A0A5C6ZM14_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF368 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007163">
        <property type="entry name" value="DUF368"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37308">
        <property type="entry name" value="PTHR37308"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04018">
        <property type="entry name" value="DUF368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="156"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="201"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="306"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="331" mass="36513" checksum="C66B11F4BD35A84D" modified="2019-11-13" version="1">MQRQLKDYIVLSLKGVAMGAADAVPGVSGGTIALISGIYEELIGTIGAVNFSLLKTLKNQGFKAFWQQLNGNFLLALLSGIAVSFVLFMRLAKYLLEQHPVLIWSFFFGLIIASIYFVGKQIKKWNVLNVFLLIIGAIAAYYITTLPSMGANSNPFFLFFAGALAICAMILPGISGSFILVILGAYKTLSDALHDFDLKKIIIFMTGAVIGLLSFSKVLKWLFKNYHNPTLALLTGFIIGSLNKVWPWKKTISVLNETTGEVANFIEVSDVGTLSIFQQQTNDFETYKTVIEESISPFSYAGNPQLLWAILLMVFGFLLIFILEQIGTKQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM46</accession>
    <name>A0A5C6ZM46_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF3108 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03575</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021457">
        <property type="entry name" value="DUF3108"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11306">
        <property type="entry name" value="DUF3108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022688215" evidence="1">
        <location>
            <begin position="19"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="259" mass="29185" checksum="8C93F59EF55272E6" modified="2019-11-13" version="1">MKRIILSLVLLISAKALSQNTSIAIGEKLTYSASYVMSGLLTDLAEVTMETSEVNTSKSKLMKLKCTAATYTKWDSFFKIRDLYESYVSPSSLTPYLYNRDINEGGYNKFMKYKFDHKTNTVASLKRKLKKDGSTVEEKKTVKIGNATRDLVTTLYYIRNMEIHKAKIGDNQNFTIIFDNKEMVINVKYLGKETLNSVLGKTECYKLAISLKNSDVLKGNNDNLIWLSADANKIPIYAKFKIAVGSGELKLKRASGMLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMH6</accession>
    <name>A0A5C6ZMH6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="64" mass="7064" checksum="761300F89B45875D" modified="2019-11-13" version="1">MLQNKISAKICAICGKQTEACEALKPADFADERRENVESHGMLQTKRLRKSAPSAGNKQKPAKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMM2</accession>
    <name>A0A5C6ZMM2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Carbohydrate binding family 9 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_05430</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010502">
        <property type="entry name" value="Carb-bd_dom_fam9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045670">
        <property type="entry name" value="DUF5916"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06452">
        <property type="entry name" value="CBM9_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19313">
        <property type="entry name" value="DUF5916"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022999407" evidence="1">
        <location>
            <begin position="20"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="domain" description="Carb-bd_dom_fam9" evidence="2">
        <location>
            <begin position="45"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5916" evidence="3">
        <location>
            <begin position="248"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD90183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="735" mass="84235" checksum="A2C4C6380B0FF052" modified="2019-11-13" version="1">MKEHIVLFIFLACYSVVYAQETANFPPPQTPLEVTVIKATSSIKIDGILDETDWENAPITDDFFRIEPNQGGANKYKTEVRFLYDDKNLYVGAFCKDSVGLKGIRVQDLRRDFLFGENDIIAIQLDAQNTKQYAVSFQTTPYGNQRDAQIFNDNNTDNDWNALWFVKTTRTEDGYYAEFAIPFKSLRYDKPEDGKPVEWGLTMFRLARREYEQTVFPAIPQAYSPYRMTYAAKLTGLEVPEPSANIRIEPYSLYQFDESKSGDAVTASDNQLKVGGDVKWAINPNAVLDLTINTDFAQADVDRAVNNLERFNIFFPERRQFFLENSGIWAGASDFAVVPFFSRRIGLQGGFNAEPAPLDVGARFTDKDENRTLAGLYVHQRETDNSAAANFGIFRYAQNYGKENNVGVMLTHRLDESFSELGLDRANNTTLTVDGLIRPKNELTLEYLGSGSYDEATNIKGIAGKVFAGYQANNFYAGWLTNFVSRDYLSGTGFVFQNDVIQHNPGGYYIWRPEKIKWIRRWDPGVFVDFYHDFENPENFQQASINIFPIFTWFKDNSFVQASLTPTWQNINFDFSPLGLAIAQGNYRYTRYLLSYNTDQSKKLSASMKYRFGNFYDGSLNTVEAGLRYAPIPHIALSGSYEHNTLKNIGILDADLETDLYTASLRLALNPKVQLSTFYQYNSFDEQGRWNVRYSWEYMPLSFIYLVFNDTQTDAFDPIQRNTQFISKITFLKQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMM6</accession>
    <name>A0A5C6ZMM6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_02940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="77" mass="9180" checksum="FCD512A25E351C86" modified="2019-11-13" version="1">MKIPAMAYVVFTTLLLLTLTIAVAMDMPFNWVFYLTCIGQVFVVIMVYKVLRDKYTTTKTFEDFYEDFPITERKNYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN24</accession>
    <name>A0A5C6ZN24_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF3124 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_04830</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021471">
        <property type="entry name" value="DUF3124"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11322">
        <property type="entry name" value="DUF3124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="169" mass="18926" checksum="2C5F2BDAE7BA9973" modified="2019-11-13" version="1">MKQVLLLCALIAIMCSCEQPRALSSTNPVNWEKRMVKTALPDSLETGSTFLSIYSQIHVRNENEFSTLTATVSLHNPNRIGDLFIDAAVYYDTKGAPIRTYFEKTIRIKPMETVQIIIDDKDDTGGTGANFVFDWQKLPKQNAPIFEAIMISTYGQQGISFVTVGKELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN78</accession>
    <name>A0A5C6ZN78_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">HD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_02900</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043760">
        <property type="entry name" value="DUF5706"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18967">
        <property type="entry name" value="DUF5706"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="247"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="273"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="370"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="HDc" evidence="8">
        <location>
            <begin position="25"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD90920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="421" mass="48979" checksum="A0A719209B461B45" modified="2019-11-13" version="1">MASDLIKKTEAFVFELFKNELDPSYLYHNYKHTERVLKSTKEIIEHSEISEEDILILKLAALLHDTGYIDGTKNHEERSVEIGTKFLNEQNVDQAVIEKVNACIMATKFNDSPKTELDKIIRDADSSHFGKDYFEEASEFLRKELELREIKSFTGKEWRDENIKMLSKKHQYYTDYALKNWQESKEENLTDLLKAKKKQKRKYDKEKIKAKYKAQYKNESPERGIQTFFRVALRNHIKLSDIADTKANILLSVNAIIISLVLANMIAKLDNNAYLIYPTAIFTLFCVVSMILSIIATRPNITSGEFTKEDVKNKDVNLTFFGNFHKMKLEDFEWAITELLKDKNYVYSSLTKDLYFLGVVLERKYRILRITYTVFMIGIIVSVITFAVALKTNGKNIDDVLPQPLAPTSYIQQDKTQSFWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN82</accession>
    <name>A0A5C6ZN82_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 10">Phosphoenolpyruvate synthase</fullName>
            <shortName evidence="10">PEP synthase</shortName>
            <ecNumber evidence="6 10">2.7.9.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9 10">Pyruvate, water dikinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">ppsA</name>
        <name evidence="14" type="ORF">ESY86_05170</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 10">Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP + H2O + pyruvate = AMP + 2 H(+) + phosphate + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:11364"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.9.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 10">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 10">Belongs to the PEP-utilizing enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.9.2" evidence="6 10"/>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008986">
        <property type="term" value="F:pyruvate, water dikinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006090">
        <property type="term" value="P:pyruvate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008279">
        <property type="entry name" value="PEP-util_enz_mobile_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006319">
        <property type="entry name" value="PEP_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018274">
        <property type="entry name" value="PEP_util_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000121">
        <property type="entry name" value="PEP_util_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023151">
        <property type="entry name" value="PEP_util_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036637">
        <property type="entry name" value="Phosphohistidine_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002192">
        <property type="entry name" value="PPDK_AMP/ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43030">
        <property type="entry name" value="PTHR43030"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00391">
        <property type="entry name" value="PEP-utilizers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02896">
        <property type="entry name" value="PEP-utilizers_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01326">
        <property type="entry name" value="PPDK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000854">
        <property type="entry name" value="PEP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52009">
        <property type="entry name" value="SSF52009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01418">
        <property type="entry name" value="PEP_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00742">
        <property type="entry name" value="PEP_ENZYMES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00370">
        <property type="entry name" value="PEP_ENZYMES_PHOS_SITE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PPDK_N" evidence="12">
        <location>
            <begin position="17"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers" evidence="11">
        <location>
            <begin position="381"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers_C" evidence="13">
        <location>
            <begin position="479"/>
            <end position="778"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00021623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00033470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR000854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TXD90140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="803" mass="88940" checksum="1B250291B78BCC6A" modified="2019-11-13" version="1">MKSRIKKFSEIGIRDVASVGGKNASLGEMYNELTSKGVRIPNGFATTSFAFWEFLKENNIQTKLETILTQLDRDAYANLKDIGKQARALILSATFSEAFSEEIKNEYTLLCGKDLKEVAVRSSATAEDLPDASFAGQHETYLNVKGGTALLEAVKKCFASLYTNRAIKYREDKGFKHDDVALSVGVQIMVRSDKGCSGVGFTIEPESGFENVILLSGVWGLGENIVQGTVSPDEFYVFKPSLAHNKYPIIQKKLGDKKLTMIYAEADQEKTITNIETPKDKQEQFVLTDNELITLAKWATLIEDHYQKPMDIEWAKDGITSELFITQARPETVHNTRNKNIHIAYKLINKGKLLSQGNAVGSKIAIGKARLLTSPKEADQLTPDTIIVTDTITPDWDPLLKQVAGIVTNKGGRTSHAAIVARELGVPAIVGCGDATQTIKNGDAITLSCAQGKTGYIYQGACAFEEEEIDFSNIILPKTEVKLILADPESAFQLASYPNNGVGLLRMEFIITHHVKVHPMALVKFDQIKDDSVKKAIEKITVTYTDKKDYFIDKLSQGIATIAAAFYPKEVIVRLSDFKTNEYANLIGGKDFEPHEENPMLGFRGASRYYNDLYKDGFVLECKAIKKAREDMGLTNLKIMVPFCRTLEEGRTVVAAMAENDLKRGDKGLGIYTMVEIPSNVILAEQFAEIFDGFSIGSNDLTQLTLGIDRDSELMKDLFDENNDAVKQMIKMAIHSAKKTNTKIGLCGQAPSDSPEFASFLVKEGIDSISFNPDALLQGIENINKAEKDLKKVDEHDDFIFYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNF5</accession>
    <name>A0A5C6ZNF5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GTP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00045</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="169" mass="19493" checksum="B6888A770EE04C36" modified="2019-11-13" version="1">MELSNKIALRPRFSLELDQDPELLLSAFENAGRAKEGFVTSRVDDHVFIRFPKSKQTFWSPQLHLEISKMEAQPTVLKGLYGPNPTMWTLFMFLHFFVATLFISAGIWLYTNTRLGAATTLPLVALILLFILWFVLYFVGRLGRKFGKDEMLLLQDFMYKILNATINPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNY2</accession>
    <name>A0A5C6ZNY2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_01825</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="108" mass="13083" checksum="C42A41AB9E222330" modified="2019-11-13" version="1">MKVVVSKSMLPKGYLGITLCPFIVLKYKYLKSDAVFMNHERIHLQQQLELLILPFFIIYVMEFFLRLLFLRNWSQAYRSISFEKEAYANDGNLDYLKSRPFWRFIKFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZP78</accession>
    <name>A0A5C6ZP78_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Gliding motility-associated ABC transporter permease subunit GldF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">gldF</name>
        <name evidence="7" type="ORF">ESY86_01170</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032688">
        <property type="entry name" value="ABC2_membrane_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019860">
        <property type="entry name" value="Motility-assoc_ABC_perm_GldF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12679">
        <property type="entry name" value="ABC2_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03518">
        <property type="entry name" value="ABC_perm_GldF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="95"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="165"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="219"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD91227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="242" mass="27078" checksum="BF13BC921BCFB654" modified="2019-11-13" version="1">MFAILKKEINSFFASPIGYLVIAVFLLLNGLFLWLFKGEFNILDNGFADLSSFFLLAPWILIFLVPAVTMRSFADEKKQGTLELLLTKPISLFKIVLGKYFAALLLIIIAIIPTLLYVFTISKLGMPEGNLDLGSILGSYFGLLFLIAAYTAIGIFSSSVTDNQIVAFIVAVFICFFLYFGFEGLTNYNLFGDSLYIERLGMASHFNSMSRGVLDTRDIVYFLSVTTLFIVFTKVMLKRASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPB7</accession>
    <name>A0A5C6ZPB7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Gfo/Idh/MocA family oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00920</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="3"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="319" mass="35505" checksum="F4A5F770BB5E02A5" modified="2019-11-13" version="1">MLKAGVLGAGHLGKIHLRLLKQSENYELVGFHDADAENGKAVEAELGYKYYSSMEDLIEAVDMVDIVTPTLSHYECAKKAIAKGKHIFIEKPITNTVEEAEHIRELLAEHDIRGQVGHVERFNPAFIAVKDQINNPMFIETHRLAEFNPRGTDVPVVLDLMIHDIDIILSVVKSKVKNVSASGVSVISDTPDIANARIEFENGCVANLTASRISLKNMRKSRFFQKDAYISVDFLEKKCEVVKMKDAPTTPGDFDMILQNAEGVKKQIYFDNPEVSKNNAILDELDSFAHAINTNTTPIVTLHDGTEALRVATMVINQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPC7</accession>
    <name>A0A5C6ZPC7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NYN domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03855</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041966">
        <property type="entry name" value="LOTUS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021139">
        <property type="entry name" value="NYN_MARF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025605">
        <property type="entry name" value="OST-HTH/LOTUS_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01936">
        <property type="entry name" value="NYN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12872">
        <property type="entry name" value="OST-HTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51644">
        <property type="entry name" value="HTH_OST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH OST-type" evidence="1">
        <location>
            <begin position="170"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="248" mass="28074" checksum="7B6489F91D9B9331" modified="2019-11-13" version="1">MKDKNLAVLIDADNVPYAHVKEMLNEIAKYGNPTIKRIYADWTMPTVSGWKNILLENAITPIQQYSYTSGKNSSDSALIIDAMDLLYSKKVDGFCIVSSDSDFTRLATRLREAAMFVIGIGEKKTPQPFITACDKFIYIEILKKAQDSDSTEKPKKQPNAKTETSSVSKIDKNLIKLMKESIDEISDENGWAFLGTLGSYIIKKKPDFDPRNYGFPKLYPLIKKIGVFKIEEKETGVNNIKHIYIKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPJ1</accession>
    <name>A0A5C6ZPJ1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Lipid A deacylase LpxR family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_04165</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018707">
        <property type="entry name" value="LpxR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037107">
        <property type="entry name" value="Put_OMP_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09982">
        <property type="entry name" value="DUF2219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="320" mass="36481" checksum="2DB4EF611DD711D2" modified="2019-11-13" version="1">MQRLILTIGLALFFFGIGRAQKIQHLEAFRSINSERYFRFHYDNDFFAATDEIYTQGYHFEFVAPVFSKNPLNFMLLKPEGFKTKFGLSLEHIGFTPNHYELPEIQYGDRPFASAIMLKSFSVSTHTQQKLRWHSSLSLGLIGPGAFGEEMQVGIHKWTGNKTPLGWRHQIKNDVVINYQVGIEKQVFQFNDILFLQAQSTLDVGSLFTNISAGANLVVGQFENVFSSEAKEGRFQIYAYAQPVVTAVGHDATLQGGLFNTRSPYTISNGNLERFTAQFNFGLVIQTKRLYFEYSRSSISKEFETGETAKWGGFRVGYRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPK6</accession>
    <name>A0A5C6ZPK6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_03050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017996">
        <property type="entry name" value="Royal_jelly/protein_yellow"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10009">
        <property type="entry name" value="PTHR10009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03022">
        <property type="entry name" value="MRJP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="349" mass="39330" checksum="28E336B3C9EC2662" modified="2019-11-13" version="1">MNKLIFLLGFISIIGCKSNPAPIASEKEITVVKTFTGQQVTGVSISDQGRLFANFPRWSAGVEQSVVEIEENGDSNTFPDKKWNSWNMEQPINDSLFIGVQSVIAMEDHLYVLDTRNPLFKGVLDNPRVFVFDLKNNKLTRTYIFQEDSFHKDSYINDLRIDKKKQKAYFTDSGHAGLVVLDLVSGTTKRVLNDHPSTLAETDHLVIDGKRWDNTVNSDGIALDTKNNLLYYHALSGYSLYAVPTDILINGTEATIQKNVKLIKKTPAPDGMILDEKGNLYFADLENHSIMKLEVSTGAMTVFAKDPKIRWADTFSIYKNVLYYTNSRINEVTGPITEMTFDIHKISLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPR9</accession>
    <name>A0A5C6ZPR9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="21">Bifunctional aspartate kinase/homoserine dehydrogenase I</fullName>
            <ecNumber evidence="21">1.1.1.3</ecNumber>
            <ecNumber evidence="21">2.7.2.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="21" type="primary">thrA</name>
        <name evidence="21" type="ORF">ESY86_01480</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-aspartate = 4-phospho-L-aspartate + ADP</text>
            <dbReference type="Rhea" id="RHEA:23776"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57535"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>L-homoserine + NAD(+) = H(+) + L-aspartate 4-semialdehyde + NADH</text>
            <dbReference type="Rhea" id="RHEA:15757"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57476"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="1.1.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-homoserine + NADP(+) = H(+) + L-aspartate 4-semialdehyde + NADPH</text>
            <dbReference type="Rhea" id="RHEA:15761"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57476"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="1.1.1.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 1/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 3/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 1/5.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 3/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">In the C-terminal section; belongs to the homoserine dehydrogenase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">In the N-terminal section; belongs to the aspartokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.3" evidence="21"/>
    <dbReference type="EC" id="2.7.2.4" evidence="21"/>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00015"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00063"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00462"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004072">
        <property type="term" value="F:aspartate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004412">
        <property type="term" value="F:homoserine dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005106">
        <property type="entry name" value="Asp/hSer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001341">
        <property type="entry name" value="Asp_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042199">
        <property type="entry name" value="AsparK_Bifunc_asparK/hSer_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018042">
        <property type="entry name" value="Aspartate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011147">
        <property type="entry name" value="Bifunc_aspartokin/hSer_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027795">
        <property type="entry name" value="CASTOR_ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001342">
        <property type="entry name" value="HDH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019811">
        <property type="entry name" value="HDH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43070">
        <property type="entry name" value="PTHR43070"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13840">
        <property type="entry name" value="ACT_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00742">
        <property type="entry name" value="Homoserine_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03447">
        <property type="entry name" value="NAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000727">
        <property type="entry name" value="ThrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00657">
        <property type="entry name" value="asp_kinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00324">
        <property type="entry name" value="ASPARTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01042">
        <property type="entry name" value="HOMOSER_DHGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="15 21" id="KW-0418">Kinase</keyword>
    <keyword evidence="19" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="17" id="KW-0521">NADP</keyword>
    <keyword evidence="14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18 21" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13 21" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACT" evidence="20">
        <location>
            <begin position="399"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00005056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00005062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00005139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00007952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00010046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="TXD91341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="814" mass="89624" checksum="E2BD8954AC9E1087" modified="2019-11-13" version="1">MNVLKFGGTSVGSAENINKVISVLDKYAKEDRLICVVSAVGGITDRLLKAGNFAQAKNENYISEFDAIKQIHSSILLELIPSKNEVILKQLEAKLQLLRSLLDGIFLINELSPKTSDKLVSFGELLSSYIITETMKSRGMEALRKNSQELIVTNSNFTKADVVYEQTNTNIKTYFEQATQRITIMPGFISKSLTGEITTLGRGGSDFTAAIAAAALKVNRLEIWTDVSGMFTANPKLVKQAYPIESLSYQEAMELSHFGAKVLYPPTVQPVLKLNIPIHIKNTQHPEAAGTTISNDAGKSTSPVKGISNINNVALLTLQGNGMVGIPGFSKRLFETLAQERINVIFITQASSEHSICFGIDDKDGVLAKAAIDFTFENEISLNKIDPIIMESQLSIIALVGDRMKSHQGISGKMFSTLGKNNINIRAIAQGASERNISAVIAEKDVKKALNTLHERFFETETKQLNVFITGVGNVGQKLVAQIAQQKSYLKEHLKTRMKVVGLSNSRTMVFDETGLDLKNWKDQLANGETASLEGFLDRAKDFNLRNSIFVDVTANDAIPKLYPAYLKQNIAVVACNKIACSSDFENYRELKDLSRKYNAPYLFETNVGAGLPVIDTLNNLIASGDRITSIQAVLSGSLNFVFNHFDDSTKFHDVVKQAQKEGYTEPDPRIDLSGVDVARKILILARESGTKMNLEDIENDAFLTKNNLESDSVDAFYETLIEDEAHFQKLYASAKANDSQLKYVAEFNEGKAKVGLKEIPRGHPFYNLEGKDNIVMFYSLRYPEQPMIIKGAGAGADVTASGLFADIIRAGNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZQG6</accession>
    <name>A0A5C6ZQG6_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Malonyl CoA-acyl carrier protein transacylase</fullName>
            <ecNumber evidence="3">2.3.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">fabD</name>
        <name evidence="6" type="ORF">ESY86_02575</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>holo-[ACP] + malonyl-CoA = CoA + malonyl-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:41792"/>
            <dbReference type="Rhea" id="RHEA-COMP:9623"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78449"/>
            <dbReference type="EC" id="2.3.1.39"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the fabD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.39" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004314">
        <property type="term" value="F:[acyl-carrier-protein] S-malonyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.366.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001227">
        <property type="entry name" value="Ac_transferase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014043">
        <property type="entry name" value="Acyl_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024925">
        <property type="entry name" value="Malonyl_CoA-ACP_transAc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004410">
        <property type="entry name" value="Malonyl_CoA-ACP_transAc_FabD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016036">
        <property type="entry name" value="Malonyl_transacylase_ACP-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00698">
        <property type="entry name" value="Acyl_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000446">
        <property type="entry name" value="Mct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00827">
        <property type="entry name" value="PKS_AT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55048">
        <property type="entry name" value="SSF55048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00128">
        <property type="entry name" value="fabD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_AT" evidence="5">
        <location>
            <begin position="5"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000446-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD90863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="293" mass="31230" checksum="13488688FC131ECE" modified="2019-11-13" version="1">MNAYIFPGQGAQFTGMGLYLYENSHLAQDLFEKANSILGFHITDIMFEGTAEALKETKVTQPAIFLHSVILAKTLGGTFMPDMVAGHSLGEFSALVANGTLTFEDGLKLVSQRAQAMQKACEAQPSTMAAVLGLEDAIVEKICAQTEGLVVPANYNCPGQLVISGEVAAIERACEALKNAGARRAMILPVGGAFHSPLMEPAREELAAAIENTTFSKPNCPIYQNVTAYEVTDANSIKKNLMSQLTAPVKWTQSIQQMVADGATHFVEVGPGNVLQGLVKKIHKAAETSSANL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZR39</accession>
    <name>A0A5C6ZR39_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GAF domain-containing sensor histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_00220</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="186"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD91060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="395" mass="45127" checksum="34D125245E61BFD0" modified="2019-11-13" version="1">MITPELTRTEEERINSLRTYKILDTLPETDFDNINKLVAMICDVPISLIALMDEKRNFFKSHLGIPFNESPREISFCNHTILEDDLLIVNDAREDERFHDNPLVTENKVVFYAGAPLINKEGLALGTICVYDFKPRDLDDHQKEALRILAVQVVNLFELRKKNILQEDAERELKQRYEHLNDFAGHVSHDLKSPLANIESLTNLLRADESNVFSEESLEFLNYIEESTNILKDYIDGILMYYKADELLKRNTEDFSLSELTEDIENILIQKNDELILTEDAIMKNVNKAALSQILINLVDNALKYNDKQRKVVEISYTSDLFHHKFTVSDNGIGIPKDKQEFVFKIFKTLKKDSGKTSTGIGLSTVKNLVEKLGGTISIESEKGNGSAFSFTIAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZR84</accession>
    <name>A0A5C6ZR84_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_00455</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD91100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="228" mass="26208" checksum="1A936BC439AD4F0D" modified="2019-11-13" version="1">MEEKSNKPNNPNNQRKPGKKPYYKKRPTPKPVKKKFWNADKIVSLSAMAIALFTLAVLLYQSYILDRQYELTVKQQKASVLPYLQLGQSYGSKYYTVFVSNQGLGPAFIDGLYVKELDSTTKISDIYNYYHKNTNNASDSLVSDYYSSLTKGMVLSPGETLELYSSKGEKSGIRPVYDFFNRYFDDDDSEIIMVEYRSVFDDSWIVESTLENIPKEDYGEIQVSSKQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6Z9E2</accession>
    <name>A0A5C6Z9E2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000068">
        <property type="protein sequence ID" value="TXD86338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023078955" evidence="1">
        <location>
            <begin position="19"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="188" mass="20819" checksum="B8DA1A82912A0012" modified="2019-11-13" version="1">MKTLFFFLVLATSLSLNAQITKGNWLVGGNFRFYSENSENTSNDFTTTQKGFGFNLSSNLGYFLKDRLAIGLVPTFGYGNPEGSGNSGYGFGIGPFARYYFLETDKRINIFSHLEYQFGNGYSNGDKVTENRNFNIKAGPSIFFNSSVAIEITLEYAYGKVTSLSGIGSESKINNFNIGIGFQIHLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6Z9P0</accession>
    <name>A0A5C6Z9P0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">IS91 family transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_20080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000056">
        <property type="protein sequence ID" value="TXD86499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007069">
        <property type="entry name" value="Transposase_32"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04986">
        <property type="entry name" value="Y2_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="159" mass="18603" checksum="436026B1E61B316A" modified="2019-11-13" version="1" fragment="single">WVVFANQPFGSPKYVIEYLGRYTHKIAISNHRITDVDRKNRSVTFTAKDYRRAGKKVNLTLSSQEFVRRFALHVLPKGFTRIRHYGILSSSWKKEKLPKLQAELATVKIEPVRTKEPLLHRRCPVCKKGRLHTILLFNDRGPPENWRVLLKDRKLNGSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6Z9U7</accession>
    <name>A0A5C6Z9U7_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase</fullName>
            <ecNumber evidence="2">2.5.1.145</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2 3" type="primary">lgt</name>
        <name evidence="3" type="ORF">ESY86_20520</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + L-cysteinyl-[prolipoprotein] = H(+) + S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[prolipoprotein] + sn-glycerol 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:56712"/>
            <dbReference type="Rhea" id="RHEA-COMP:14679"/>
            <dbReference type="Rhea" id="RHEA-COMP:14680"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57685"/>
            <dbReference type="ChEBI" id="CHEBI:64716"/>
            <dbReference type="ChEBI" id="CHEBI:140658"/>
            <dbReference type="EC" id="2.5.1.145"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; lipoprotein biosynthesis (diacylglyceryl transfer).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the Lgt family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.145" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000083">
        <property type="protein sequence ID" value="TXD86204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_006987059.1">
        <property type="nucleotide sequence ID" value="NZ_VORO01000083.1"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00664"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008961">
        <property type="term" value="F:phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042158">
        <property type="term" value="P:lipoprotein biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01147">
        <property type="entry name" value="Lgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001640">
        <property type="entry name" value="Lgt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30589">
        <property type="entry name" value="PTHR30589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01790">
        <property type="entry name" value="LGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00544">
        <property type="entry name" value="lgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01311">
        <property type="entry name" value="LGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="23"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="104"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="187"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="245"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)</name>
            <dbReference type="ChEBI" id="CHEBI:64716"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="276" mass="31511" checksum="66DF730C50D5FC6B" modified="2019-11-13" version="1">MNDRIINWNLDPVIFWITESFPLKYYGLFFMIGILLAFYVEKRIYAKENIPIENLDKLFIYVVVGILLGARLGHCLFYDPSYYFANPLEILLPIKKIGDSYQFIGFQGLASHGGTIGVLIAIGIYCKKYKTNFLSVLDKISIVAPIVAAFIRFGNFMNSEIYGKPTNGNWGVVFQRDDLIPRHPTQLYEAFSYLLIFGILVLIYKKKKEKSNGLILGLALVLIFLARFIIEFFKENQVDFESGMLINMGQILSVPFIIIGLILILARKKPSVQHSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6Z9W7</accession>
    <name>A0A5C6Z9W7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000098">
        <property type="protein sequence ID" value="TXD86037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023151676" evidence="1">
        <location>
            <begin position="23"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="117" mass="13801" checksum="82EAAA7AE0AA9B08" modified="2019-11-13" version="1">MKRNFKYILIILTFGLFQNLLAQENKVGKVKVVKYRDTSDRFTESTTDSTLAYLNKREHDILITNKKDTTRLKTNSLGIFEIPKKYFNYCSITVNPKTKDLREEFLFMEGLGKKDMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAG9</accession>
    <name>A0A5C6ZAG9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_20190</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000060">
        <property type="protein sequence ID" value="TXD86437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="405" mass="47792" checksum="1443BCFBCC2FCAAD" modified="2019-11-13" version="1">MNKDNIPNNIQSVIHRIKFIDMLYSNRVNFQGPLNYNLEYDFHPFQHFYSTINYLLLTCLDTLSEKEKFEDFDIWVKKENNLERDQILENFDSNKLNYKELTQNLYSKYKEKHGIVKSIRNFVFNELKTETRVKLFNSISVIKYSKIKGKEVKQEIIDDNKIFKYLLDVRNKFTHSAFIFAGWDDNSPMIGAPTNFMLWDGKIGNVSQNWTKVEQTKFTYKNVTLKGWPYIIREVLADYIYDKYKIDISLKTIKLKEYRGEYNFDLLWSEYDKILLAKREDGKNIFVGGSAFKSAKEAIYFMDCKVGDAIKLDNPSKYGIKSGDVYLLEFSKYKYLNPVNDLIGTVISESGKKYFVRYNKPERMFLFSQVFGSTWACREIEDTDYLTILDRALLAINDNEKAEGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBV6</accession>
    <name>A0A5C6ZBV6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_20695</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000105">
        <property type="protein sequence ID" value="TXD85974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD85974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="182" mass="21629" checksum="C3347823D3668CD7" modified="2019-11-13" version="1">MNKVLIIFLIIGLYSCGEKQKSEKKAEIVEVEKTASKLKDFELVQDFEQNKAEFRIDKFELNDHSADGGELTVFHNKNFDYVVLDFWLYGETGKLNYTFWTEKEGNMKFKFVKQLKYEYDKPYYVENYKTDSIIRYLTYSDSRIKLFDINKTEITESEQIEKSKSELESFFTDVTKGIEIIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCM4</accession>
    <name>A0A5C6ZCM4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19355</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000039">
        <property type="protein sequence ID" value="TXD86765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="95" mass="10639" checksum="CACBD1E9D767572B" modified="2019-11-13" version="1">MKLNLKNQRLVKLEPSLLIVFLAHSSQLTAHSSQLTAHNPQPTTHNPIFGVLAPFGPDIYRQGQEHDAENPINFALTLKGIIGFSRIETTQNIWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCP6</accession>
    <name>A0A5C6ZCP6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17480</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000027">
        <property type="protein sequence ID" value="TXD87227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="61" mass="7125" checksum="E48695BDE0ED44D0" modified="2019-11-13" version="1">MFSTGQLVFGILFAIVFIIALIYAYRKDSKLHRKYYKGSVWILIAFISFLLMIAAIKFIFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCP7</accession>
    <name>A0A5C6ZCP7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ArsC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006660">
        <property type="entry name" value="Arsenate_reductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30041">
        <property type="entry name" value="PTHR30041"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03960">
        <property type="entry name" value="ArsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51353">
        <property type="entry name" value="ARSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="119" mass="13657" checksum="0652B0FB27FFDEA7" modified="2019-11-13" version="1">MKKFYFLSTCSTCKNIIAALNLDASVTFQDIKSKPLTAEQLDALKKLAGSYEALFSKRAQLYKTKNLKDQTLSETDYKKYLLEHYTFLKRPVLVYDDQIFIGNSKKTVEAATAFIRSHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD15</accession>
    <name>A0A5C6ZD15_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18425</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000031">
        <property type="protein sequence ID" value="TXD87034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="65" mass="7005" checksum="8EB8897425574AA8" modified="2019-11-13" version="1">MKILSIILSVLAIAIVVFNVTKLDFNNLFAGDSLTALICITASLCAILLLQILSVSKKIEQKVKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD48</accession>
    <name>A0A5C6ZD48_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type II toxin-antitoxin system RelE/ParE family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_16780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000024">
        <property type="protein sequence ID" value="TXD87434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007712">
        <property type="entry name" value="RelE/ParE_toxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05016">
        <property type="entry name" value="ParE_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="105" mass="12417" checksum="EFD98D81119A919E" modified="2019-11-13" version="1">MAFKIIWSEFAEIQLDEIYEYYEKKASSKIAAKLVKGIISAPGKLITSPYIEQAEDLLKERKIQYRYLVFKNYKRIYAVDKENGFIKIADVFDTRQNPPKMKRTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDA2</accession>
    <name>A0A5C6ZDA2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ImmA/IrrE family metallo-endopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_17745</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000028">
        <property type="protein sequence ID" value="TXD87159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.680">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007044">
        <property type="entry name" value="Cyclodeamin/CycHdrlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036178">
        <property type="entry name" value="Formintransfe-cycloase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010359">
        <property type="entry name" value="IrrE_HExxH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04961">
        <property type="entry name" value="FTCD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06114">
        <property type="entry name" value="Peptidase_M78"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101262">
        <property type="entry name" value="SSF101262"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FTCD_C" evidence="2">
        <location>
            <begin position="10"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M78" evidence="3">
        <location>
            <begin position="318"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="193"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD87159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="472" mass="53184" checksum="DEA4055B98C8CF02" modified="2019-11-13" version="1">MEVNLLDITTEELLEKFGAGNHKPGSGSAAAFQGMLSAKLLVTVISLTNEEKRRHKYKIILPQLLVKDNDIQERIFPDLTRLFHEDAIQFGRTITAREERDNEVDLFKNNKLGRTALDELKVSIEIPLSIGKLCIELAEISELVFESGFQSARGDSQVALSGSIAGLAGCLSIIQLNLLSFGSDEYFWTSKIIVEAKKLKSRYQELNESATAKIESLEKEVDSKAKLYNKVDKLLKRVKSKSKLNNTDIQEVVSELQNLMWIHKNTIWPSNTPGDPTKVLMPSTVFRKALGFKYSLTSDIGVLERDNEYTEIAGLIDQKDKIVLISSGYDDNIQNFTAAHELGHAVLHTQTIMHRDRPINGTTITGKRSLQEIQADKFATYFLMPSKLVQQIFRELFLTNKFVINDNTAFLLTNDSSADKLKNRCKNLRGLALKLASTERYNDQSFLSIAKLFNVSTTAMAIRLEELELIEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDC5</accession>
    <name>A0A5C6ZDC5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC-F family ATP-binding cassette domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_16950</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000024">
        <property type="protein sequence ID" value="TXD87467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032524">
        <property type="entry name" value="ABC_tran_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037118">
        <property type="entry name" value="Val-tRNA_synth_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16326">
        <property type="entry name" value="ABC_tran_CTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="4"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="313"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="528"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="554"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="537"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="345"/>
            <end position="352"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD87467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="622" mass="72054" checksum="5C117AA345718647" modified="2019-11-13" version="1">MNYINVESISKSYGELELFSNLSFSIHKDDKIAFVAKNGSGKTSILNILSGADVPDDGQIVIRNGIRLAFLSQNPEFEPELTIEQAIFNSDLPVLKIIENYEKALQNPENADAYQKAFEQMDMNNAWEFETQIKQILFQLKLDDLSQTIKTMSGGQVKRLALAHALIINPDVLILDEPTNHLDLEMIEWLEQYFAKAQFTLFMVTHDRYFLERVCNEIIELDHGQLYTYKGNYTYYLENKETRIAQEEVETGKAKQLFKKELDWMRRQPKARTTKSKSRIDDFSDIKKRAHQRRKDHNIELEINMERLGSKIVEFHKVSKSFEDKVILDNFEYTFKRGERIGIIGKNGTGKSTFLNMLTNSVQPDGGKIVIGETVKFGYYTQGGIKIKPGQKVIEVIKEFGEFIPLTKGRQISAKQLLERFLFDGKKQHDFVEKLSGGEQKRLYLCTVLIQNPNFLILDEPTNDLDIVTLNVLEDFLLDFPGCLLVVSHDRYFMDKIVDHLFVFKGEGKVKDFPGNYSDYREYEDSNASEALSETQNESVSEEKEEQNKAEKLSYNEQKEYKNLESKIRALELDKKELEAKFLDSSLSQDKINELSKKLQRIIDDMAKKEKRWFELAERLGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDF5</accession>
    <name>A0A5C6ZDF5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_17945</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000028">
        <property type="protein sequence ID" value="TXD87197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038740">
        <property type="entry name" value="BioF2-like_GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13480">
        <property type="entry name" value="Acetyltransf_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="1">
        <location>
            <begin position="46"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="Acetyltransf_6" evidence="2">
        <location>
            <begin position="675"/>
            <end position="769"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="799" mass="91163" checksum="542267A5A98CC656" modified="2019-11-13" version="1">MAKIKHNNFLDTVNDVFTDAIDEGVLHLYADGESFSGRTIGVNGKNLFHFGTTGYLGLEQDPRLKAAAISAIERFGTQFPLSKSYISNPLYRELEEKVTQMYNNPVVITKNSTLGHLGVIPSAVKDQDAIILDHQVHWSVQSAAKMLKTRSVPVDMVRHNDLNMLEDKIKSLSGTRKRIWYMADGIYSMFGDYAPIKDLKALSEKYPQLYLYFDDVHGMSWIGKNGTGYVMSEINELSENMLLFGTLSKTFGASGSVLVCSNKKLYREIKTFGGPLTFSAQLEPASVAAATASAKIHLTPEIYTLQNDLKERTQYFNKLLRETDLPLIDKNDSPVFFIGTGMPNTGYNFVNRLMKDGFYVNLGLFPAVPVKNTGVRITISRHNQYEEIKALVDAMVYHLPKAIEETNTSLNRVYQAFKLETKQKTALDSNNDLTIQLVDSISKIDKNIWNTLVGTCGVQDWDGLKFLEETFSNNKLEENNWKFWYVIINDNKNVPVLASFLCACLWKEDMLASVSASKTIEDERKTDPYYMTSKVLSLGCLFTEGDHLYINTKHALKQEALNLFLHSTEKLEVESNSKMIVLRDFDGNEDLHTYFQGRGFIRLQMPDACQIQLHPEESIEQYINNLSARNKRHFRNDILKHESELDVAIVQKLNGSQIKQAQNLYNNVRENNLGLNTFKYPAKLFENMSHHPNWEFIIINTLENNDRMIGIMFCYKNNNLTYVPSLIGLDYDYIKNHQTYRQLLYQTIKRAIQLNLRHIDLGLTASFEKRKLGANINEKFAYIQTSDNYGLELLGLLEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDI1</accession>
    <name>A0A5C6ZDI1_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3 4">Single-stranded DNA-binding protein</fullName>
            <shortName evidence="2">SSB</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ssb</name>
        <name evidence="5" type="ORF">ESY86_19035</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000036">
        <property type="protein sequence ID" value="TXD86851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04496">
        <property type="entry name" value="SSB_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00984">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000424">
        <property type="entry name" value="Primosome_PriB/ssb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011344">
        <property type="entry name" value="ssDNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10302">
        <property type="entry name" value="PTHR10302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00436">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002070">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00621">
        <property type="entry name" value="ssb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50935">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR002070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD86851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="104" mass="11718" checksum="EE1B47697821D6D6" modified="2019-11-13" version="1">MSRLRNKVQLIGNLGKDPGIMKLESGKTLAKYSIANNESYKNAKGELVKDTQWHNIVAWGKTAEIMEKYLIKGKEIAIEGKLTSRSYDDKEGVKCYFTEVVCCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDL1</accession>
    <name>A0A5C6ZDL1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18920</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000035">
        <property type="protein sequence ID" value="TXD86885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015209">
        <property type="term" value="F:cytosine transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030191">
        <property type="entry name" value="CodB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30569">
        <property type="entry name" value="PTHR30569"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="182"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="267"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="310"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="352"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="378"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="420"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="442"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="471" mass="51446" checksum="590DBB72859353BA" modified="2019-11-13" version="1">MSQYNIEEEIEEIAGGEFERIPVPQSKLKSWKSFLGMYAGEHAAGTEFMIGPLFLTAGVSAFDLIIGLLLGNLLAVLSWRFLTAEIAIKNKLTLYFQLEKICGKKLVTFYNLANGVLFCFLAGAMITVSATAVGIPFDMEMPKLTDTMPNGATWEIIVIVIGAVISLIASRGYDTVSKAANWMSPAIVLAFLACGIVALNQLGVASFSDFWNIWGEGSEPFPGQIKFTFWHVVIWSWFANAAMHVGMSDLSVFRFAKKASSGWTTAAGMYVGHYMAWIAAALLYAVYLKSPEALNFLANGEAPPVAPGPLANNAIGVFGIIAVVLAGWTTANPTIYRAGLAFQAIIPKASTFWVTILAGSIATIAGLFPAFAMQLLGFVALYGFILAPFGAIIVFEHFFHKKYGIIKNYAEVANIKFNKAVIFAWAISFGLFYFISIQFDVFLSFVTLPSWLLCGVLFLVFSKYFQNKNSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDR2</accession>
    <name>A0A5C6ZDR2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_15535</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="241" mass="28987" checksum="FAB1AAC330B96AC1" modified="2019-11-13" version="1">MLKNLIYTIICLTSILSFSQTIKSIVEFKKVGDSLVENRLSEFDDSENLIKEVKYGNYDSRLKTFRNKIRTIEYSNGHRVSDYFCEHFVSEDTCVVRSFSTFEFDEKTGIEKQIKYESDSLIRFIRDTKKTKQMKSSKTFSWELSPVEKPDFEKAIVFMDTIFYDQEQRKIKRVSYNNRKQKPLIELYDYSDKKYTYQTIGRFRDTTLTFQYGKLRKLADKKSLNYIFQDPQNYSYEIEYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDS5</accession>
    <name>A0A5C6ZDS5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="10">30S ribosomal protein S6--L-glutamate ligase</fullName>
            <ecNumber evidence="10">6.3.2.-</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">rimK</name>
        <name evidence="10" type="ORF">ESY86_13810</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.-" evidence="10"/>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013651">
        <property type="entry name" value="ATP-grasp_RimK-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041107">
        <property type="entry name" value="Rimk_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004666">
        <property type="entry name" value="RpS6_RimK/Lys_biosynth_LsyX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08443">
        <property type="entry name" value="RimK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18030">
        <property type="entry name" value="Rimk_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00768">
        <property type="entry name" value="rimK_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="10" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="ATP-grasp" evidence="9">
        <location>
            <begin position="104"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD88170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="290" mass="31491" checksum="F7E27FE1C32A3B4E" modified="2019-11-13" version="1">MNIVILSRNPHLYSTKRLVEAAKQRKHTVEVIDPLKCEIIIEKKNPAVLYKGKPLEGVDAIIPRIGASVTFYGTAVVRQFEMMKVFSTVESQALVRSRDKLRSLQVLSRAGLGMPKTVFSNYTKDVAEVIKYVGGAPLVIKLLEGTQGLGVVLAETNNAAESVLEAFNGLHARVIVQEFIKESKGADIRAFVVDGNVVGAMKRQGKEGEFRSNLHRGGSANIIQLTDEEENAALKAAKSLGLGICGVDMLQSARGPLILEVNSSPGLEGIEAATKKDIAKTIIRFIERNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDS7</accession>
    <name>A0A5C6ZDS7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15575</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022880838" evidence="1">
        <location>
            <begin position="24"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="318" mass="35207" checksum="F81F5B0790AB311E" modified="2019-11-13" version="1">MKKLLCFRTLAILMIMLSIIGCKTEKKKDTTTEDQSTENSKNDTISIITRGMEFQSVDTIPSGWNTFKYQNLSNETHFFLLDKYPEGKTVENALTDVVPVFEEGMDLINEGKAEAGFAAFSKLPKWYSEIVFSGGSGLIAPKHTAITTVKLAPGYYMMECYVKMPNGKFHSAMGMAKPLIVTEEDNGNSPPEATINITLSGEEGITYDTSITKGEQLFSVFVKDQKPHENFIWHDVNLVKLDKNASEDALEAWMDWSDPKGLITPVPNGVTFLGGVNDMAAGSTGYFMADLKPGNYALISEVPNTKSKNLFKVFEVLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDW2</accession>
    <name>A0A5C6ZDW2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_14560</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="286"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="331"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="377"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="21"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="316"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD88104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="414" mass="45959" checksum="FA81E4D89C7DD77A" modified="2019-11-13" version="1">MFDLERWQEIFETLSKNKLRTFLTGLSVASGIFILVILLGFSKGIENGVKSQFEQDATNEISVRTSRTTKSYKGLNPGRYVQLTNESYDAVERKFDPYLEYRSKTFMVWGGTVSYGNESGNYRISGVLPDNQFIENADIGTGRFVNHSDVVESRKIAVIGNKMKQDLFKDESPIDKNISVYGVNFKVVGVFFDPGGEREESQLYIPITTAQRVFNAGQDIRNMSFTMKMEDNFDKAVKKSEAISQGIESQLKEIHIVAPDDVSAVRVNNTLEEAQKIYSLVATIQAVFWFVGIGTIIAGVVGVGNIMLIIVKERTKEIGIRKALGAMPMSIVGMILQEAVFVTMFSGLFGLVFGLGLLELVGPQIENDFIKYPQVDFNIALTTVFLLVLAGAIAGFIPAYRAAKIKPIVALRDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE62</accession>
    <name>A0A5C6ZE62_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Acyl-CoA thioesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_15270</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="158" mass="18017" checksum="4234C0A6959870FE" modified="2019-11-13" version="1">MYKKEFEIRWSDVDGNGHMANSAYLNFMSHTRVGFLNENGFSMKELIAHGVGPVVFSEHIHYFKESFLEQKLTVSLDVSGLSDDGKFFKFEHNFYNGKGRHLATCDILGGWIDLKTRQLVSLSEPLLTKIKAFPKSADFKTLTKEDTRASGKRPKHLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE64</accession>
    <name>A0A5C6ZE64_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">LysM peptidoglycan-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17165</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000025">
        <property type="protein sequence ID" value="TXD87399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="SSF54106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LysM" evidence="1">
        <location>
            <begin position="73"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="126" mass="14192" checksum="F3CFDE47D71B490A" modified="2019-11-13" version="1">MVKSKYQSVLDLGEQLNIQHGDVKVENGVLKMHGTAPTQYEKDLLWDEIKSVGGENPSDIMADIKVADTSVYHRHTVKKGETLGKIAKHYYGDASKYQKIFKANTDVLKNPDMIHPDQELVIPNKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE75</accession>
    <name>A0A5C6ZE75_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphoenolpyruvate carboxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_15390</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>oxaloacetate + phosphate = hydrogencarbonate + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:28370"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="4.1.1.31"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008964">
        <property type="term" value="F:phosphoenolpyruvate carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015977">
        <property type="term" value="P:carbon fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021135">
        <property type="entry name" value="PEP_COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30523">
        <property type="entry name" value="PTHR30523"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00311">
        <property type="entry name" value="PEPcase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00150">
        <property type="entry name" value="PEPCARBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD87853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="860" mass="98008" checksum="FB0404ACFD91567F" modified="2019-11-13" version="1">MPTQPKLTRFNQNVLSKYQIYNSIFMTLPFDSITKTGVLLPLFHETCKKGFQDGDNPTTIVETFFKKYQARRSKESQTNLLFRFIQYIERQVVLFDAIEDAAFPIVNNMDGVGTLRSLTESASSENKLQELQQYLKEFKVRIVLTAHPTQFYPGSVLGIITDLTAAIKANDLLTINDLLAQLGKTPFFKHEKPTPYDEAVSLIWYLEHVFYFSFGSIYDYIQQNIFEGQHIDNDIINIGFWPGGDRDGNPYVTPETTLKVAARLRESILKNYYRDIRRLKRKLTFKGVEERLSALETGLYDAFVFPGKESITLEHFVMELGAIKATIIKDHQSLYLEQINSLLNKTRLFGFHFGALDIRQDSRAHAAVFNTVVDKVIASGSEVFPKDYQTLSEAEQIKTLSAIKGTIDISLFEDEMVLKTLNSMKAIKTIQQENGEKAANRYIISNNQSTLHVMQLFAMLKIVAFEDDLTVDIGPLFETIVDLENAPAVMEELYTNSHYAAHLKKRGNKQTIMLGFSDGTKDGGYLMANWGIFKAKERLTAVSRKYDVTVIFFDGRGGPPARGGGKTHQFYASLGPTIEDKEVQLTIQGQTISSNFGTMDSSQYNLEQLISSGILNRLNDTNTAMSKENTEVMEDLAQLSYKTYSDFKSHKMFVPYLERMSTLKYYAKTNIGSRPSKRGNSDKLVFEDLRAIPFVGSWSQLKQNVPGFFGVGTALKHYEDNDEFEKVKHLYESSNFFKTLVENSMMSLSKSFFDLTKYMADDEEFGDFWNIIHNEYETSKRLLLKLTDAEVLMQEEPTGKASIDVRESIVLPLLTIQQYALKKIQELERAEVRDQEQIDIYEKIVTRSLFGNINASRNSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEA6</accession>
    <name>A0A5C6ZEA6_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transport permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_16915</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ABC-2 integral membrane protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000024">
        <property type="protein sequence ID" value="TXD87460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006648">
        <property type="entry name" value="DrrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="54"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="254"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="7">
        <location>
            <begin position="34"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD87460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="288" mass="32675" checksum="B07ECB05DC7B6BF2" modified="2019-11-13" version="1">MSATNSDDWLYTISSKNKLIDINFKEIWRYRDLLLLFVKRDIVTVYKQTILGPLWYVIQPLFTSVIFTLVFNNLGSISTGGVPPFLFNLAGITAWNYFNACLTGTSDTFKQNAGIFGKVYFPRVIMPMSVTISNLLKFFIQLFIFAGFYIYYYSSGAEVAVNSNVLLFPVYVIMMALLGLGAGMILSSMTTKYRDMTVVIGFAVSLLMYMSAVPYPLSEARKKFPTLVADFVEYNPVTQIIEGFRYMLLSTGSFSWSGFFYTLVFSMVLFLVGIVVFNRTEKTFIDTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEB9</accession>
    <name>A0A5C6ZEB9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sugar transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_16945</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000024">
        <property type="protein sequence ID" value="TXD87466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015159">
        <property type="term" value="F:polysaccharide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003715">
        <property type="entry name" value="Poly_export"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02563">
        <property type="entry name" value="Poly_export"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="264" mass="29626" checksum="5AAE1876C09B2F23" modified="2019-11-13" version="1">MKRLLLLTGLVLCVLSTSCIPHKDIVYLQNKSTATDSMQVMVEQQKPYRIQINDILNIRIKVLDQDDVTIFNPIGEGSMNASASERAYFDGFTVDVHGNIRIPELGDMNVLGFTTEAIETRIKDKLLEEQFKETANIFITVKLAGLRYTAFGEVGSPGSTVLFMERVNIYEAIANVGEIPITGNRKEVKIIRQYPQGQKIHELDLTDVNVMQSPYYYIQPNDMIYVMPLKQKTYGTGTTGRESLATIVGILSLVTTTILLIDRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEQ2</accession>
    <name>A0A5C6ZEQ2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Sugar MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">ESY86_16450</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Intake of glucose and galactose.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the major facilitator superfamily. FHS transporter (TC 2.A.1.7) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87618.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005354">
        <property type="term" value="F:galactose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005355">
        <property type="term" value="F:glucose transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005964">
        <property type="entry name" value="Glc/Gal_transptr_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01272">
        <property type="entry name" value="gluP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="9 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="102"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="140"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="193"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="244"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="281"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="309"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="334"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="366"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="414"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TXD87618.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="442" mass="47149" checksum="76BC7B01523C9B42" modified="2019-11-13" version="1">MTTSNSKNNLVPILIIAGLFFIFGFVTWINGALIPFMKTINELSDAQSYLVASASYISFVVMALPASYILTKIGYKKGMSLGLFVMGIGALVFIPAAEARTYWVFLAGIFIQGMGMTILQTAANPYATILGPIESGAKRIAIMGIANKTAGALGSLIFGAILLSGIDAVQDQLKDASETEKALLLDTMADSVFVPYVIMAVVLFILGILIRKAPLPHVEPVEVEADLAIDGAGAKKSIFSFPHLWFGVFALFVYVGAEVIAGDTIINYGISLGISGDEAKFFTTFTLMAMVATYALGVFLIPKYLKQRTALIGSAILGVILSVCILLTTGYTSVLLVAALGIANAMVWPAIWPLTLDGLGRHTKTASALLIMAISGGAIIPPLYGRLVDSNKNEMIASGINDADALATASTGSYWILIPCYLIILFFALWGNTLKSWKRVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZES9</accession>
    <name>A0A5C6ZES9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyl hydrolase family 16</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_16040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000021">
        <property type="protein sequence ID" value="TXD87667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008964">
        <property type="entry name" value="Invasin/intimin_cell_adhesion"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49373">
        <property type="entry name" value="SSF49373"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="468" mass="49896" checksum="A61007D080E28560" modified="2019-11-13" version="1">MTKINNVFSKNHWAVLLLFFAITSCERELSDEAVFAEFPANGDVFTDAFSAGLDYFPFVGEGADPEAFSVVTDEVFEGNAAMRFDVPSFGNGFVGATFNTTVKRNLTGYDALTFYAKASQAATLNDVGFGIDGDINNKYLTTLSGLEISTNWKKYVIPIPDASKLIGEAGLFWLAEGASFDGDEGGYTLWFDEVRFENLGTIAQSDPAIFSGQDLTQQSFTDSSIIISGLTQTYNLASGINQTVTTAPSYFTFSSSDTGVAIVDELGVISVIGEGTALITAIIDGVEARGSIQINATGGLQSAPAPTLPQANVKSIFSDAYTNATEIDFAPGFGGSTTETALVGGAGDSFLSYANNNFTGIIFNDTVDASALTFMHIDVYVQEAGTEVGIQIRDIGANQEIETNQFTGFPDGDDKDYRTDLTNLSVGQWTSFEIPLAGGIANQKNNLGAIIITGGPNFILDNIYFYTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF45</accession>
    <name>A0A5C6ZF45_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_13915</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the BI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006214">
        <property type="entry name" value="Bax_inhibitor_1-related"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23291">
        <property type="entry name" value="PTHR23291"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01027">
        <property type="entry name" value="Bax1-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="18"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="82"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="146"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="169"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="199"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD88191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="225" mass="25069" checksum="A07B425EBA7EA223" modified="2019-11-13" version="1">MVSQLATDARVAFYKKTYAHVAGGVLVFILFEWLLLQSETIVDFTLSLTQGWRWLIMLGGFMFITNYAEGMALKTKDKNKQYLAFGLYILAEAFIFVPLIYIAAYYMESGPEILNQAAIVTLALFSGLTAVVFVTKRDFSFLKTGLTIGFFIAIGLIVAGSLFGFNLGLWFSVGMCLLAGAAILYQTSNLINKYAVDEYIPASLGLFASLMLLFWYVLSIFMSRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFA9</accession>
    <name>A0A5C6ZFA9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">FtsX-like permease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_13395</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="286"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="332"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="378"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="423"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="679"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="728"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="760"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="20"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="318"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD88298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="799" mass="89110" checksum="364AEE192D7A0BAF" modified="2019-11-13" version="1">MIRNYIKIAFRNLKKNKVYSFINIFGLALGLAVTMIIGLWIVDEFNYNDHFESKDQIAQVMQNQTINGSVETNEGLPLALEFQLRDHFGDAFESIVMSSRPDERYLSLKDKVISSSGRFMQVDAPDLLELDMLEGTRKGLKETNAILLSETTAQTLFGSESPLGKSIVSDNEHTMVVTGIYKDIYKNNSFNGMHFIMPFKHWMSTRWGWLENQDSNWSYNPFFIYVKFSENADLAAVNARIVNLKKDNLPVGDVFNSQLFLFPMADWYLHSNFENGKQVGGRIENVWLFGIIGLFVLLLASINFMNLSTARSEKRALEVGIRKSIGSTRRQLIYQFLSESFLVVLVAFILAIGLVLVSLPAFNTIAGKDVIFPWSSSLFWMVSLGFIGFTALVSGSYPALYLSSFKPIKVLKGTFKMGKFAALPRKVLVVTQFTVSIALIIGTLIVKDQIDYSKNRPVGINSAQLIQLPTSSQDFSGKYDLIRNAFLSSGSVAKMGWGTSPATSIWNYSSGFEWDGKPVDFNESFAQMAISFDYIDAVGMKIIEGRSFSRDFATDSNAVVLNKTAVDYMGIKNPVGKYIRGTAAGPNDVPMQIVGVVEDVINESAYEPVSPQMYQFGHGTGGFYYLRLNPNQATSKSLASVEKIFKTNFPNLPFSYDFVDEEYAQTFAAEERIASLAKVFTLLAILISCLGLFGLASFMAEQRKKEIGVRKVLGATVTNLWLLLSKDFILLIAISICIAAPLAYYFMSDWIEKFFYRTDISIGVFLIAGLGALLLTVITVSFQAIKAAIANPVKSLRTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFK9</accession>
    <name>A0A5C6ZFK9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FixH family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008620">
        <property type="entry name" value="FixH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05751">
        <property type="entry name" value="FixH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="148" mass="17465" checksum="85A1B8D107274C3D" modified="2019-11-13" version="1">MKINWGTGIVLAFIGFISFIMYFVIQMNVDEKLSYDLVTEDYYGKELEFQEDLDKQEHAKSLTTDVTWTRTKEGLLISFPLDKDIKDITGKVFLYRPSNKQLDYETTISLSNHNLLIPDKRLVDGRWNISVDWQYHGNSYLYKKEISY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFL5</accession>
    <name>A0A5C6ZFL5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">S8 family serine peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_12965</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase S8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07483">
        <property type="entry name" value="Peptidases_S8_Subtilisin_Novo-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.200">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017308">
        <property type="entry name" value="Pept_S8_subtilisin_bacteroid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000209">
        <property type="entry name" value="Peptidase_S8/S53_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036852">
        <property type="entry name" value="Peptidase_S8/S53_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023827">
        <property type="entry name" value="Peptidase_S8_Asp-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022398">
        <property type="entry name" value="Peptidase_S8_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023828">
        <property type="entry name" value="Peptidase_S8_Ser-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015500">
        <property type="entry name" value="Peptidase_S8_subtilisin-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034080">
        <property type="entry name" value="Protease_P7-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00082">
        <property type="entry name" value="Peptidase_S8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037892">
        <property type="entry name" value="Subtilisin_rel_SRU_0565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00723">
        <property type="entry name" value="SUBTILISIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52743">
        <property type="entry name" value="SSF52743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00136">
        <property type="entry name" value="SUBTILASE_ASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00137">
        <property type="entry name" value="SUBTILASE_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00138">
        <property type="entry name" value="SUBTILASE_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0720">Serine protease</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022810804" evidence="7">
        <location>
            <begin position="21"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S8" evidence="8">
        <location>
            <begin position="81"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S8" evidence="8">
        <location>
            <begin position="267"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="258"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="258"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD88423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="537" mass="58211" checksum="E114E44341CB6415" modified="2019-11-13" version="1">MKHIFKPFIYSIFAASILFACGGGSSFVSTPIENIDTSPIKEKELTTTELNSWSHLDLAKDTIPGMSVDRAYSELIKNKKGKTVIVAIVDSGVDIDHEDLNGVIWTNKDETPNNGKDDDNNGYVDDIHGWNFLGDGYDEQLEYVRLIAAGDKNAPRYDEAEALYNSEYQKWLGRKTQYDQIYQQITVANDVLTKHFGKSDYTKAEVAAIKSDDEELMQAVQVAQFIYGNNMDSMAIAIEEIKGGVESINDRLNADLNKDLKGRKTGDDPNDFDDKPGYGNNNPRPSTKSESHGTHVAGIVAAERNNGKGMNGIASNVEIMAVRTVPNGDEYDKDVAKAIRYAVDNGAKVINGSFGKSFSPHSDWVRDAIKYAAENDVLFVHAAGNDSDDIDVASNYPNDAIGTGPEISDNVITVGALAPNYGSSMVSSFSNYGLVNVDVFAPGTDIYSTMPENEYDLNSGTSMAAPNVAGVAAMIRSQFPSLNASQVKKAILDSGLPIQAEVVIGKDKESKSLSEISKTGRIVNAYNALILAAKMAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFQ9</accession>
    <name>A0A5C6ZFQ9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_10605</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032808">
        <property type="entry name" value="DoxX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13564">
        <property type="entry name" value="DoxX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD88937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="117" mass="12542" checksum="197CC9054A74A429" modified="2019-11-13" version="1">MIGALTVVTLFSAASFVFYGISCLTSKRMLLEFERFGLAKQRALTGVLQLIGGFGLAIGFYASFKLAAFSAAGLAILMLSGFVVRLKIKDSVVASAPALMYALLNGYLALRFFGVWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFS7</accession>
    <name>A0A5C6ZFS7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">CvpA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_13125</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009403">
        <property type="term" value="P:toxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003825">
        <property type="entry name" value="Colicin-V_CvpA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02674">
        <property type="entry name" value="Colicin_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="61"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD88450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="177" mass="19403" checksum="160D35E8E9DCC86D" modified="2019-11-13" version="1">MAIIDIVLVVLLLFGLIRGFMKGFFVEVASLVALIAGVYGAIHFSDFAAEFLDSKVDWDEKYINIVAFAITFIVIVLIIAMAGKALTKLADFAALGILNKLLGGVFGLLKIGLILSVLLIVFDTMNATIPLTKKEDLKDSILYEPVKSLAPMIFPELLKKGKEQLEEIDEEEPNTEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFZ3</accession>
    <name>A0A5C6ZFZ3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Toll/interleukin-1 receptor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12395</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003953">
        <property type="term" value="F:NAD+ nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019677">
        <property type="term" value="P:NAD catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13676">
        <property type="entry name" value="TIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="SSF52200"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0675">Receptor</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TIR" evidence="1">
        <location>
            <begin position="99"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="313" mass="36012" checksum="450CD674CFE6315B" modified="2019-11-13" version="1">MKKLQKIELIDKIGRELQERMKFNEIDGYFESYGIPTDHQPSYNSKYVYVKEVLPKVNDEIVLEIASELGIEHEAVFSIPVIVKESEATFWKPGHFKLFVSHLASFKKTIGILKAELEKYGISSFVAHEDIEPTKQWQDEIEKGLFSMDAFCAVLMEGFKESNWTDQEVGVAVGRNVLIIPIRRGLDPYGFIGKYQGFQAIGKNVGQVAEGVFEIISCHKKTKSKYLNTLVELILLSNTANQGIERLKALKKVKDLPKEKVEYLQDKITDNENLKETRFLNPFNEIAWRYKLEGLSLESFEKVIEEDYDDLPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGI7</accession>
    <name>A0A5C6ZGI7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_09245</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023014159" evidence="3">
        <location>
            <begin position="22"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="335"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="172"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="461" mass="52493" checksum="B569BF44F6B430E3" modified="2019-11-13" version="1">MKTKITVIIAALLMATNFSFAQQNENCMLNLTLMNDYVKNKKYDQAYEPFMSVRKECPKFNLIIYKFGEKVLNHKIDNSSGAEKEAFIEDYIALLNEAGEHFPSKYAKGEVLEGIGILLYDNQELLNKSDMDVYNAFDNAFKQDLKNFTSTKGLYVYFTKTVDLFKAKEIELQQVFDKYDDVSEQLENLNEGYTKSVNELIEKEEAGTALKDKEALYKKYYLDKLEANGKISGSLDSYLGQLANCENLIPLYKKQYEEKYNDAVWLKRAVSRMYNKECTEDPLYIELVKKYDEVDPSADTKYFVSTILREQGKIKEADQYVRQSFDLQTDKFKKARLAKRIAAGFKNRGDYSTARNYYRDALELNPSDGTPHLHIASMYAKSANSCGDDNFNKRAVFWYAAQEARKAGQVDPNLRSNSSQAAASYEANAPTRSEIFTKGNGGSTINIGCWIGGSVVVPKVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGL7</accession>
    <name>A0A5C6ZGL7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_11365</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="92" mass="10575" checksum="A60107FCB1A22628" modified="2019-11-13" version="1">MDTLFTKEPTFSFSEMNQTYYNYNSKELNERLFSNINSIENTYIDHETFLRGCGYLENGVTNPIDSAGLMLSLILNNFLNNVLLTNGIFSKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGM3</accession>
    <name>A0A5C6ZGM3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_11415</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="173" mass="19550" checksum="637F83753CFCABCB" modified="2019-11-13" version="1">MGTFKFEVKQVMKKRLILVIVTLTLTNLLAFSQVKKVDFGIKGGLNLTFFNVEQADFGPNARSETGYYAGAYVDFEIDEFLSIQPELLYVGLNDFRFLNAPIYAKYEVADKFNLMVGPSLNYFFDFFTDKFKVRGDLSAAYQITPALNAHIKYTLGFEVLAPNGLFFGLGLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGP6</accession>
    <name>A0A5C6ZGP6_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3 4">Single-stranded DNA-binding protein</fullName>
            <shortName evidence="2">SSB</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_09645</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04496">
        <property type="entry name" value="SSB_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00984">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000424">
        <property type="entry name" value="Primosome_PriB/ssb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011344">
        <property type="entry name" value="ssDNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10302">
        <property type="entry name" value="PTHR10302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00436">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002070">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00621">
        <property type="entry name" value="ssb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50935">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR002070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD89293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="118" mass="13143" checksum="0C295819E6A1E0DE" modified="2019-11-13" version="1">MSTLRNKVQLIGNVGNEPEITNLESGKKVARFSIATNEFHKNPNGEKEQNTQWHNIVAWGKIAEIVEKYVGKGKEVALEGKLTSRSYETKEGEKRFITEVVIDEILLLGIKGDDSSNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGR6</accession>
    <name>A0A5C6ZGR6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">SLC13 family permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_10575</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004680">
        <property type="entry name" value="Cit_transptr-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03600">
        <property type="entry name" value="CitMHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02080">
        <property type="entry name" value="TrkA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="29"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="57"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="91"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="139"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="173"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="412"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="455"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="486"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="517"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="541"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="575"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="8">
        <location>
            <begin position="206"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD88931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="602" mass="66057" checksum="F5AD70DA20C529B8" modified="2019-11-13" version="1">MDVQIILIFAIIGVSVVLFVTEIMPIDKIAFFIIVALALTGVTTPEDAISGFSNPAAITVLMLMIIAIGLEDNGVIGFLSKSIKRLSTLPLLLMVPVFMVVSASISSVISTTAVVIIFLKIFTTISEKFNFPTSKLLMPISFAGILGGSCTLMGTSTNLLVNSVASKYGVERFSFFEFSLYGLVFLAIGVVFMTIASRFLPKNTKDKLSEYSENSNFLFTLIVRPESKYVGAAFSEVPFYNNPNISVLKLVRQNTVNTAPGKNTTLRANDELVLMSDIQDFSLISEDDFILSLESDEIENQKVLDKNMKFTYLELLILPGSEFIDKSLQEIKFLFNSIGQPIGIQKKKMLQLDEHLYLPKAFKKLVVKAGDRILLKINKKQLENIYNYTNVVVLRHHEDDFKVDPYKRLWCVIVLLAVIALAATSVLSILTSTIAGVGALLLADCINLSKIYKRVNWQIFFLLAGMIPLGVAMGNTGADLWISGKLLYLLSGQGSTIVLGSLFAMTMIMSGFISNNATAVIVTPIAIALATSLQLPVKPFVLAVMFGANFSFFTPMGYQTNALIYGTGIYRFKHFLIIGGLLSIILLIAGTLLLSTMLNTQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGS4</accession>
    <name>A0A5C6ZGS4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_10625</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="154" mass="17589" checksum="EA481D5E3B025247" modified="2019-11-13" version="1">MVPVKEAINSGSWLHCECNDYDRLIKFRLKISSFRKLVLTEIDNPDKIGTIDEGAMLWLMQIEFINLTKDPIHPRYGPPYLLLIDQDGFRFHIFEDGHLESGSQFSKTSGMHRFGYTELIPKIKAVGSIVFQLPDDADAEYSISIKNNGVVQEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGT5</accession>
    <name>A0A5C6ZGT5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_13170</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023064560" evidence="3">
        <location>
            <begin position="19"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="105"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="154"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="154"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="230"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="258"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="277" mass="31864" checksum="FBC848052BBB5D66" modified="2019-11-13" version="1">MKFTLSLLCFSLTFLLFAQDKDELKQEQLSLKKANGFVYHANELVDADNYVSAEKEYRKAISEQPTNVAGTYNLGNSYYEKGNYDEALFRLAQAAKNGKTKTEKHKAFHNIGNILMKNKKCKEAVEAYKDALRNDPSDDETRYNYALAKVCADKQEDQKKDKDDDKKDESKDDKKDKEDKKDDKGDDKGDDKKEDQKEGDDKKEENGKPKDDKKDEGKNDKKDEKENQGQPKQQPGQLSPQQIKNILEAMNNQEQKVQEKMNAEKQKGTPVKSEKDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGV0</accession>
    <name>A0A5C6ZGV0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15435</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="67" mass="7831" checksum="7F0988287B5D758B" modified="2019-11-13" version="1">MQIERTNKEILIRVSSGTDLVGLQRILDYLKFREIASKSKASQKQIDELSSESKSSWWNKNKSRFVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH39</accession>
    <name>A0A5C6ZH39_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">T9SS type A sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_08730</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001434">
        <property type="entry name" value="DUF11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01451">
        <property type="entry name" value="B_ant_repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022936564" evidence="2">
        <location>
            <begin position="24"/>
            <end position="1278"/>
        </location>
    </feature>
    <feature type="domain" description="Por_Secre_tail" evidence="3">
        <location>
            <begin position="1206"/>
            <end position="1274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1008"/>
            <end position="1032"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1278" mass="143053" checksum="60F08E38624679B0" modified="2019-11-13" version="1">MRVMKTKLYLILLLFFGFQAIEAQVQKVETYLVGTKVTYYPNQCGNTIPEAQGKLSFCDSQNNLGVVETSYGLNYRGISQMAPNYYNTDEVFVTEAGVSIRKTDGSWDNIPEFTAPRTNPYGNSPQMREVIVNNQGYMFFYHGSNWGLHYLDLNTKTYSTVSYATSTGGSNGNFTHSFAYDEEGDVTYIMVQSGGNSGFKVYKFESNTLSFLGNLPVEVTGENSSSKLIFANDALYFGTTTGLYKLNKTSIALEASYVTDASAFISNVKDIAEDTAGNLWLANQNNNDGAIYKLNMSNEVITTFQLARNTTTNYSFNNLDIDNNGTVWATANNLSGFAELEPTENNPTWTVRSLDDIRDLGFNMTYSPLEVNKFNNKIYIMVTNNSSSSQDVNYEAIINDNGVWSGVSDDEPNNLSNKMLNRYYFAYPDANGVWWFNDNDGGIMSHISNTDEFKKQYSLGNSESFTLDYDGNPIINGGSPYTRMQKIYMPYVADLPSIGTNAITQFHKYKDQIWVFSNTTRKIFVFKHNQLIQTFNLDDTTYNTWYDFTPDIYGNAFFAKRLGGNELELRKFDTNTQTTTSYINSTYLGNIKQMIPLPNGNVAVICSSGIFLFDGTGLSAIGSSMYADLFNVATGISDLNGKIYLLSTSGKLIGIENPEAPTPIFSTIQVSGTSGLVPYNAFYGPTTLAIDANGAFWSHASIKWFKITTDNTVAQFLNEGITFGITGSVYVDVNENNQFDANEGYPNQKLTLKTSSGAIFELYTKPDGSYYFPYFEGLGTYEIILPVLSPYVVAPERQHILNVANLDADTNVNDIKLQPKDIESLLVKSSSKQGAWGFTRSNFENTFTTAIGNISFSKTFNNVTMDYVFFNKTAGSNNSLPAVENVKVSRLQPVQPFHIIHKLTIEPRSHKWNTNVNPDSYTSTILSLTPTITTLTDTTKVSFTLPVISPLDTYILEVETQLFTPSSNGTVISYGVAKTSSEDYGDGVPEMNVVELIPRNPVDGQGFPELSGPFSTPEEIYGEPPYRPRKDVYADGPYDTPIRSSYDPNDKLVNPGVPDALNEIPLNEKWLTYTIRFQNEGNFSAKDVIVVDSLDQKFDRYSLTMLESSHPLTIETLKSNEQNIVIFSFNDIYLDYTANDEVASQGYLKYIIKAKEDVELNDIMENRAAIYFDQNPPIITNLTQNKYVQVTLNVEAFRNEGKAIKLWPNPVDRFVTITTKQKAFFKVNVYNLLGQKLQSNLNFQEEHQLDVSQLKSGIYVLESILQNGKTQTIKFIKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH75</accession>
    <name>A0A5C6ZH75_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045057">
        <property type="entry name" value="Gcn5-rel_NAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031165">
        <property type="entry name" value="GNAT_YJDJ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31435">
        <property type="entry name" value="PTHR31435"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14542">
        <property type="entry name" value="Acetyltransf_CG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51729">
        <property type="entry name" value="GNAT_YJDJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="6"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="93" mass="10447" checksum="801F8F020FFD939A" modified="2019-11-13" version="1">MEIKTEINAKGGRFYIEKQGNEVAKMTFQQETDAKMNIDHTEVDESLQGQGVAHKLLDAAVAYAREHNLKVRATCSYAKSALKKNTDYNDVLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHB3</accession>
    <name>A0A5C6ZHB3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">XdhC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_13295</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003777">
        <property type="entry name" value="XdhC_CoxI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027051">
        <property type="entry name" value="XdhC_Rossmann_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13478">
        <property type="entry name" value="XdhC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02625">
        <property type="entry name" value="XdhC_CoxI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="XdhC_CoxI" evidence="1">
        <location>
            <begin position="17"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="XdhC_C" evidence="2">
        <location>
            <begin position="207"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="384" mass="42804" checksum="FC59E7CCF520A2A3" modified="2019-11-13" version="1">MRELDFIISQYENLSSQGIGCVLATVVHVEGSSYRRAGARMLVDEFGNIAGAISGGCLEGDALRKALHALHQQKNKLITYDTSDEDDAVIGAQLGCNGIIQVLFEPLDYEDSLNSCELLKSVLAQKNSLAIAVQFNLDRSKEQTGTILVIDENSEYTGRKPENEVLDLILQQAQLTLENKRSHFAEFSINGETHHLFIQNYQPPIKLIIVGAGNDAQILAQQGDLLGWEVIVTDGRPTHANKERFTSSCQVIVTKPEKTLENIEIDQRSCFVLMSHNYNYDLAVLKLLLTEDQIPYIGILGPLKKYERMQNDLESEGIRLFEEIAKKIHAPIGLEIGAETPAEIGLSILSEIQSVLTQTSARPLREKSEPIHEKKNNHFKEIKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHB5</accession>
    <name>A0A5C6ZHB5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Excinuclease ABC subunit A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">uvrA</name>
        <name evidence="15" type="ORF">ESY86_07110</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009380">
        <property type="term" value="C:excinuclease repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004602">
        <property type="entry name" value="UvrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041552">
        <property type="entry name" value="UvrA_DNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17755">
        <property type="entry name" value="UvrA_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00630">
        <property type="entry name" value="uvra"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0228">DNA excision</keyword>
    <keyword evidence="12" id="KW-0234">DNA repair</keyword>
    <keyword evidence="11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ABC transporter" evidence="14">
        <location>
            <begin position="495"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="529"/>
            <end position="536"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TXD89552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="845" mass="92115" checksum="16FD056178D7719E" modified="2019-11-13" version="1">MKQPNQDKTQKEGFVAIRGARQHNLKNVTLDIPRDALVVFTGVSGSGKSSLAFGTLYAEAERRYLESVSPYARRLFHQMPIPEVDAIEGLPPAVALQQQRGSGTSRSSVGSVTTLSNLLRMLYSRAGDYPAGQPLLYADSFSTNTPEGICPKCHGLGKVYEVTEKSMVPDDSLTIRERAIAAWPSAWQGKNLRDILTTLGYDVDIPWKELPKKDRDWILFTNDRPQVPVYRDLNLAAVQLAIENKTKPSYQGTYTGAKRHVLHTFANTQSALMKKRVSQYMLSSECPSCNGKRLRRESLSVTFAGYDIADISRLPLKKLLSIFTPYADGSAPALAKLNKHHQEKAMVAQRIAEDLVARATVLLELGLGYLSLERSTPTLSPGEHQRLRLATQVRSNLFGVVYVLDEPSAGLHPADTEALLKTLDRLKASGNSLFVVEHELDVIRHADWIVDVGPDAGDGGGEILYSGPPAGLKNTPRSKTRAHLFNELPFQKPTARKPSGWLKLSGVTRNNLTNLGVSFPLGVLTSVTGVSGSGKSSLVSQVLVELMSTKLGKGLASEEDEDTLQKDNVVTLGGEITSGSEPIKRMVVVNQKPIGRTPRSNLATYTGLFDVVRKLFAATKLAKARHYSAGRFSFNVGKGRCPNCDGEGFVMVELLFLPSVYAPCPVCEGARYNAETLEVTYHEKNITQVLDMTVDEAAVFFEQEDRVGRPLKVLQEVGLGYLRLGQPATELSGGEAQRIKLATELQRVNRGNTLYILDEPTTGLHPTDVEKLQVQLAKLVDAGNTVIVVEHDMQVVAGSDWVIDIGPGAGNEGGKVVAEGTPEEVATNKLSKTAIYLSKTLNGHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHE2</accession>
    <name>A0A5C6ZHE2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_13475</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="109" mass="12172" checksum="5FADABFDEA476BE0" modified="2019-11-13" version="1">MPSTLNARLGNDVSHNYSQIWLSSDALHEKGVQFGLESFSGKGNTGGRMFVGVLDKQREYDAIVDGDRRLNSSWPIIRDLKTTEANPLNLSSTAILGKLRTKLIILRLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHE4</accession>
    <name>A0A5C6ZHE4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Universal stress protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_14325</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal stress protein A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="2">
        <location>
            <begin position="1"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="Usp" evidence="2">
        <location>
            <begin position="151"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="274" mass="30764" checksum="BEF582CAE2E49861" modified="2019-11-13" version="1">MKKILVPTDFSKEAENALKVASHIARKNNSEIYLLHLLEIPLTNVDAINANADVPEVMFFMKMAHRKFKEILASEFLEGLTVNEVVKPDVSFSSIAEIAKEQDIDLIVMGSHGSSGFEEVFIGSNAEKVVRSSHVPVLVIKNEHEDFSVEDIVFASDFKKDNKETYRQATEFAMSFGAQIHLLMVNTPGNFTTTTKAKERIDEFIKDYSFRNYTITVYNDDSVEKGILNFAKDIDADLIGISTHGRQGIAHFFNGSISEDLVNHAKRPVITFKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHG1</accession>
    <name>A0A5C6ZHG1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_13585</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="99" mass="11456" checksum="1FCFFBCDA8B3EE2B" modified="2019-11-13" version="1">MTSEKSYGNSNMSCFDPHFAIVYYLQEKRVGTISICLECNYLIASEKITATELKIIEIPDEYSYPAKGFSKATRKEIYDYIKHIGFTKYLKPLTSYLDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHM7</accession>
    <name>A0A5C6ZHM7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_09455</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="5"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="220" mass="24565" checksum="E2347D1FCAEF7FF1" modified="2019-11-13" version="1">MKLTRVLLVDDHPIIVESYRNSIKAYEFQNKGHEFTVDSALGCESALVLINKKEYDIAFLDIRLPASKDGKYKCGEDLAKLIKSKHEATKIIIITGHYDALLLGKLLQNLNPDGLLFKGDVGSQMVSNALTSVLTNYPFYSPTVLNLLRKKMSSDIVLNKNDKLLLYELAKGTKTKDLIKCLPLSIGGVESRKRYLKGLFETKGKDDSELIIAAKKKGFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHN3</accession>
    <name>A0A5C6ZHN3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">GLPGLI family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_07580</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005901">
        <property type="entry name" value="GLPGLI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09697">
        <property type="entry name" value="Porph_ging"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01200">
        <property type="entry name" value="GLPGLI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="250" mass="28632" checksum="B17B85D3CE8F57BB" modified="2019-11-13" version="1">MKEKLIILILLITHCSIGQSLSGYADYNKKSIVNDSLLKNNDDIDPEIVRTIQKASNNLEKTNYRLYFNDLIGKYEKIKSLSSDSESKLSINMSKLLSGFIGNSAFYSKKDRIIIITEEIYGEKILIKTSFDSLNWKLTNDTKIISNLTCYKAKTKKSVEGRSGKKVIEIIAWYAPEINLPYGPDGYGGLPGLIVQLQKENIITFLKKIEFQDEMMKLKLPNKGRVMTETEFNALMKDAVINRRKHYRKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHY3</accession>
    <name>A0A5C6ZHY3_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">UDP-glucose 6-dehydrogenase</fullName>
            <ecNumber evidence="3">1.1.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">ESY86_09750</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Nucleotide-sugar biosynthesis; UDP-alpha-D-glucuronate biosynthesis; UDP-alpha-D-glucuronate from UDP-alpha-D-glucose: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.22" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00038">
        <property type="reaction ID" value="UER00491"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003979">
        <property type="term" value="F:UDP-glucose 6-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006065">
        <property type="term" value="P:UDP-glucuronate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017476">
        <property type="entry name" value="UDP-Glc/GDP-Man"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014027">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036220">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014026">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001732">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028356">
        <property type="entry name" value="UDPglc_DH_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11374">
        <property type="entry name" value="PTHR11374"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00984">
        <property type="entry name" value="UDPG_MGDP_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03720">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03721">
        <property type="entry name" value="UDPG_MGDP_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500133">
        <property type="entry name" value="UDPglc_DH_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000124">
        <property type="entry name" value="UDPglc_GDPman_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00984">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52413">
        <property type="entry name" value="SSF52413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03026">
        <property type="entry name" value="NDP-sugDHase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDPG_MGDP_dh_C" evidence="10">
        <location>
            <begin position="334"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="163"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="222"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="269"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="340"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="278"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="11"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="92"/>
            <end position="96"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="133"/>
            <end position="134"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="262"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="278"/>
            <end position="281"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="348"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="444"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR000124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR500133-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR500133-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR500133-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD89049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="464" mass="51489" checksum="20D174048081E6E9" modified="2019-11-13" version="1">MHNIKNICCIGAGYVGGPTMAVIAQKNPDIKVTVVDINEARIAAWNDADLDKLPIYEPGLDKVVAEARNRNLFFSTAVDEAIEAADMVFISVNTPTKTYGKGKGMAADLKYIELCARQIARVAKTDKIIVEKSTLPVRTAQAIKSILHNTGNGVKFQILSNPEFLAEGTAVQDLMAPDRVLIGGEQTEDGLNAIQALVDIYATWVPNENILTTNLWSSELSKLTANAFLAQRVSSINALSELCEVTGADVNEVAIAIGKDSRIGPKFLKASVGFGGSCFQKDILNLVYIAKSYGLNEVADYWEQVIIMNDYQKRRFAAKIIQTLYNTISGKKIAFLGWAFKKDTNDTRESAAIYVADQLLEEQANIVVYDPKVNAHQMQSDLNYLNTRSEEDNNQYLTTVSNPHQACKDSHAIAVLTEWDEFKTYDWQRIYEEMQKPAFVFDGRGILDKEKLETIGFQVYVIGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI18</accession>
    <name>A0A5C6ZI18_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PKD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_13440</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032485">
        <property type="entry name" value="DUF5050"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000033">
        <property type="entry name" value="LDLR_classB_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022409">
        <property type="entry name" value="PKD/Chitinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000601">
        <property type="entry name" value="PKD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035986">
        <property type="entry name" value="PKD_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16472">
        <property type="entry name" value="DUF5050"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00135">
        <property type="entry name" value="LY"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00089">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49299">
        <property type="entry name" value="SSF49299"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51120">
        <property type="entry name" value="LDLRB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50093">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022985397" evidence="1">
        <location>
            <begin position="24"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="PKD" evidence="2">
        <location>
            <begin position="53"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="PKD" evidence="2">
        <location>
            <begin position="137"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="448" mass="48002" checksum="C8162FF9A6C69B5A" modified="2019-11-13" version="1">MKTILYRYAILSLMVLAIFSCQNDDDTLPPQSQAEFTVSASEVAIGETIQFTNNSENATAYKWSFGDGTTSMQVSPTKSYTSSNVFLVSLVSTGSGGSTISNMEITVTPASSFSVEDEENLSAGLPVQFTNTSVGATSFSWNFGDGAGTTSAEENPAFTYASEGSYTVSLTATSAFGSNTSTKEITLAMAPEAPASLYYISLGDEFIRNLTLDGSGTTTDLVDLVGKGGVGLAYDATNEKIYFSDFDTYPFGNIWRADLDGANPETIVSGIGDPYAVQIDEVNAKVYWVDDDGNVSRANLDGSSPENVLNLPSAQWRALALDVENGKMYAYEVNNEDLYEANLDGSNPQIIISGIYGYAIAVDTVNDKVYFDDQNAGTFNVANLDGSNIQTVDTDGTRIYGIQIDNEDNKLYWSGRDSGELYRANLDGSEREVLASGLASPRGIVLIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI38</accession>
    <name>A0A5C6ZI38_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="10">DEAD/DEAH box helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ESY86_10935</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6 10" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Q_MOTIF" evidence="9">
        <location>
            <begin position="3"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="35"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="235"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="5">
        <location>
            <begin position="3"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD88996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="373" mass="42379" checksum="820B98484248EA65" modified="2019-11-13" version="1">MANTFSDLGIKNQFIKGLKELSIKTPTDIQEQAIPTLLKNNTDFIGLAQTGTGKTAAYGLPILQNIDPKNDEIQALILAPTRELVQQIQKQLFKFTKYCEHQIFAEGIYGGEKMDIQLKRIQRTTHIVVATPGRLLDFIERGEIDIKNIRTLVLDEADEMLSMGFKQDLNKILNYTTGTRYTWLFSATFPEDIQSMVKTYMHKDAVTVEIDKNSLVNANISHHYIVTSIKEKTNVIARLLDKYDDDRGIIFTRTKAGAMQLTENLKAEGFAVEALQGDMQQKERDKVMRAFKNQSLQYLISTDVSARGIDVNNLAFVIHHQLPDQQEYYTHRSGRTARAGKTGESIALIISGEEQEIQKLQKDLDIKFKQLTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI82</accession>
    <name>A0A5C6ZI82_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Agmatinase</fullName>
            <ecNumber evidence="5">3.5.3.11</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">speB</name>
        <name evidence="5" type="ORF">ESY86_08990</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the arginase family. Agmatinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.3.11" evidence="5"/>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008783">
        <property type="term" value="F:agmatinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901564">
        <property type="term" value="P:organonitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005925">
        <property type="entry name" value="Agmatinase-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006035">
        <property type="entry name" value="Ureohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020855">
        <property type="entry name" value="Ureohydrolase_Mn_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11358">
        <property type="entry name" value="PTHR11358"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00491">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036979">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="SSF52768"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01230">
        <property type="entry name" value="agmatinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01053">
        <property type="entry name" value="ARGINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51409">
        <property type="entry name" value="ARGINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD89184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="314" mass="35599" checksum="F1ED5AA7AA627813" modified="2019-11-13" version="1">MNTKTYAGIEDQYSKLDTSKIVLIPVPYDGTSTWQKGADKGPEAFLNASENMELYDIETKTEVYKQGVFLADAIIENTSAEAVVDAVHKTVKKYIKRNKFVTTFGGEHSISIGTIRAFNECFDDLTVLQIDAHADLRKTYHGSKCNHACAVYEASQTTNLIQVGIRSMDVMETTVMDEEKTYFAHEMAMDETWMDSAIDQMTDNVYITFDLDALDPSIMPSTGTPEPGGLFWYETLDFIRQVFEEKNVVGFDIVELCPNPEEKSSDFVAAKLYYKMLTYKFLNDNAADDYENNFKESKGNTNKISKFNNEEDHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIF9</accession>
    <name>A0A5C6ZIF9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Enoyl-CoA hydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07455</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="260" mass="27886" checksum="888B86B2D8E925BD" modified="2019-11-13" version="1">MAYNNLIAQTNNGIATITINRPKKLNALNMETIQELHEAFKDANKDTQVKVIILTGSGEKAFVAGADISEFADFDEKEGGELAAKGQKLLFDYIEALSTPVIAAVNGFALGGGLELAMACHFRVASINAKMGLPEVSLGVIPGYGGTQRLPQLVGKGRAMEMVMTAGMIDANQALEYGLVNHVTSEDELMALTEKIAGKIMRNSSVAIKAVIKAINANYKDGVDGFKTEIKQFGKCFGTEDFKEGTTAFLEKRKADFPGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIM7</accession>
    <name>A0A5C6ZIM7_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH-type transcriptional regulator</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_12480</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GbsR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026282">
        <property type="entry name" value="MJ1563"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12802">
        <property type="entry name" value="MarR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006707">
        <property type="entry name" value="MJ1563"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH marR-type" evidence="2">
        <location>
            <begin position="27"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR006707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="167" mass="19069" checksum="A920C07797BD06AB" modified="2019-11-13" version="1">MNYDEAKHKFVSTWGSLGTLWGINKAMAQIQALLFISTEPLSMEDIMAGLQISRGNTSMNLRQLMDWGIVTKEIIPGERKEFFTTEKNVQELARIVAKERSRREIKPVIKVLNEVSSIEDDGNPKTKELIKQTKDLHDLTETMDALINKLVNQKQNWITKSLLKLIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIN0</accession>
    <name>A0A5C6ZIN0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ferrous iron transport protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_07355</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007167">
        <property type="entry name" value="Fe-transptr_FeoA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038157">
        <property type="entry name" value="FeoA_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008988">
        <property type="entry name" value="Transcriptional_repressor_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04023">
        <property type="entry name" value="FeoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00899">
        <property type="entry name" value="FeoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50037">
        <property type="entry name" value="SSF50037"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FeoA" evidence="2">
        <location>
            <begin position="3"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="77" mass="8449" checksum="08A93D4205E09196" modified="2019-11-13" version="1">MQITLAQLKRGQHGIIADVSSIHIPLKLLEMGCLPGNLVELVQVAPFSDPMYLNINGTHLAIRKETALHIIIDLPDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIX1</accession>
    <name>A0A5C6ZIX1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glutaminyl-peptide cyclotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_06480</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016603">
        <property type="term" value="F:glutaminyl-peptide cyclotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017186">
        <property type="term" value="P:peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007788">
        <property type="entry name" value="QCT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011044">
        <property type="entry name" value="Quino_amine_DH_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31270">
        <property type="entry name" value="PTHR31270"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05096">
        <property type="entry name" value="Glu_cyclase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50969">
        <property type="entry name" value="SSF50969"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="343" mass="38921" checksum="91D3669026E56797" modified="2019-11-13" version="1">MISFKSFILISLSLLFINCGNQVANKSRFEIKTNAKEDVISLGETLNLSLKNPKNVEISAVSYQLNGKSVGESITLANEKLGQQTLTAIINTGDSEEKINTQITILNNKTPEIYGFKIINEYPHDITSYTQGLEFHKGELYESTGQYKESKLRKVDYKTGEVLKNIDLADQYFAEGITILDHKIYQLTWQENTGFVYDVETFEKINSFKYGKSEEGWGLCQDGKVIYKSDGTEDIWTLDPETLEEISKTQVYTNKGKIVGINEMEWINGKIYANRYQKNGVAIINPVNGAVEAVIDFSPLHNMVTQHKDLDVLNGIAYNPETKTIFVTGKRWDKLFEVEVFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIZ4</accession>
    <name>A0A5C6ZIZ4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hydroxymethylglutaryl-CoA lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_06630</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HMG-CoA lyase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016833">
        <property type="term" value="F:oxo-acid-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043594">
        <property type="entry name" value="HMGL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42738">
        <property type="entry name" value="PTHR42738"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="3">
        <location>
            <begin position="4"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="287" mass="31681" checksum="501591D91177B19F" modified="2019-11-13" version="1">MNQPVKIIECPRDAMQGIKAFIPTEKKVQYIQSLLRVGFDTIDFGSFVSPKAIPQMVDTAEVLAQLDLSKTSSKLLAIIANTRGAADACQHPEIDYLGYPFSISENFQMRNTHKTIAESVVTLGEILELANKHNKEVVVYISMGFGNPYGDPWNVDVVGKWTETLSNMGVKILSLSDTIGSSEPESIAYLFSNLIPKYPAIEFGAHLHTTPTTWHEKVDAAHKAGCLRFDGAIQGFGGCPMAKDELTGNMPTEKLLSYFTTHHKNELNALSFESAYNEATKVFTAYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJK7</accession>
    <name>A0A5C6ZJK7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DUF3526 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_08935</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032688">
        <property type="entry name" value="ABC2_membrane_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021913">
        <property type="entry name" value="DUF3526"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12679">
        <property type="entry name" value="ABC2_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12040">
        <property type="entry name" value="DUF3526"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="17"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="209"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="353"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="441"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD89494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="469" mass="53478" checksum="F4CF47C8887CB553" modified="2019-11-13" version="1">MFQIIKNEWRFLVRSRLLIAISIAFVSILLLSIFLGNYQTQKQEQTYQKATEHLRQQWVSIDAMNPHSAAHYGTYVFKPANLLSNLDEGVNSVTGNVLRVEGHVQNEIVHSEASQMQAVSRFGKLKSALLLQYIVPLLLIFLAFNTISSEKQSGRLKLLVLQGAKPLEIILSKTLSVWLYGVLLLIFVVVVYGILNFQNLTAEILTRTGLFFLSYALYYFIISGLTVFLSARWQNATLALTSMLGIWILWTIFLPNILMSSAEKWYPLPSRNEFQSAMTEDRSKGLDGHNPSDERGIALEEKVLKEYGVDSLSQLPINFDGMRMQADEEYGNSVWDKHYGSNRNILHQQKKSFQLGGIINPFIALQNTSMGFMASDNLHHQDFLLQVENYRRVFIKMLNDKQTFGGSKTGNWGWKIDNAFFKSVPDFEHRPTQISVVLSNYIMDVSLLILWSIVVIALIFFGTKKIKIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJP8</accession>
    <name>A0A5C6ZJP8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Esterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003140">
        <property type="entry name" value="PLipase/COase/thioEstase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02230">
        <property type="entry name" value="Abhydrolase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Abhydrolase_2" evidence="1">
        <location>
            <begin position="28"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="216" mass="24689" checksum="45FAFFCED0822414" modified="2019-11-13" version="1">MNSTEKDIYYTINNSYSTLNTLTEHTKNIWFVCHGLGYLSRFFLKYFKGLNPDENYIIAPQAQSKYYQSSKFEHVGASWLTKENTGAETENVMAYFDAIFAEEAILKHLSTTTIKLNVFGYSQGVSVAMRYVAKRQLQCSQLILHSGGIPSELLRSDLAFFKGKVTFIYGDQDQYINPKRLEIETEKANSLFGNQVKMIQFEGKHEVNVDLIKSLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJS9</accession>
    <name>A0A5C6ZJS9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_04615</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="208" mass="23295" checksum="3AEBF8A07466785F" modified="2019-11-13" version="1">MNSKWYISTLILVLCVLGISKQQRTIVPNQEIVLQFSNDEVDASLTEHAIANVKKQLHALGVLKINVSKPEAGLLKISYFSQLDVSAIKCLLSKEQHAKNGYAFPSEKTSRGNGFPSEDNDTTYYELKVFELHQANEMDASINGKLALESRSDKDRFFNPNDFVAVQVQIQDLQLPIKDNRLQTKLVNAIAFDDLFQKIPEVRAGPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJV1</accession>
    <name>A0A5C6ZJV1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Serine hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_04735</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021860">
        <property type="entry name" value="Peptidase_S12_Pab87-rel_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11954">
        <property type="entry name" value="DUF3471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023063656" evidence="1">
        <location>
            <begin position="26"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase" evidence="2">
        <location>
            <begin position="41"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3471" evidence="3">
        <location>
            <begin position="460"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD90062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="551" mass="60624" checksum="7596810E74D0E65C" modified="2019-11-13" version="1">MKHVAHILKLSLILGFILSASFTNAQDLEQQINSYVASEYNADTPGVSILVAKNGKIIYENAFGMANLELDVKAQPNNVFEIGSITKQFTAVAILMLEEQGKLKVSDDIVKYIPEYPTQGKTIRIHNLLNHTSGIKSYTNMPSFMSSARTDMTPVELIDVFKNEPSEFDPGTQYNYNNSGYILLGHIIEVVSGMSYSDFIQANIFDKVGMENSYYGSMTQLIQNRASGYSETETGYRNSDYLSLTLPYAAGSIMSTTADLLKWQNAISANTLIERSSLDKAINGSELNAGDAIPYGYGWQKGDINGSKTVEHSGGIFGYSSNGIFLPEENVYVIGLSNCDCGSVGGITANIAAMAIGKPFPKKEDAITLTEAQLQKWVGAYAFNNDVIRHVSLKEGQLYSLREGSRTMEIYPMTEVNFIFDGGATTYEFYTEDGNRMVKFTANGNTEIGKGIDKALPSEKESITLPTETLKQYPGKYELQPTFHIVIEVKDDKVFATATGQQQFEVFASAKDEFFLKVVPAEIVFNRTADGTVESLTLKQGGNNMLGKKLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJW7</accession>
    <name>A0A5C6ZJW7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_04840</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="81"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="140"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="170"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="222"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="256"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="288"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="311"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="348"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="374"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="14"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD90082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="404" mass="44645" checksum="00C1F6C492455644" modified="2019-11-13" version="1">MKQLFHFLKSNASDVSFGWVLTFLSSFGQTFLISLYVPKIIEKFALTEGSFGGVYAIATIISSVILLSVGHTIDHKSVKKVTAFTLLGLACSTFLLGFSHYHIALLIISLIGLRLCGQGLLSHISLTVMSRHYQRDRGKALSIASLGYAMGEAIFPIGITTLIALYGYEIAARVSSVVIILYLIRLYFIDTSHFDNKASIAQKHSFRVLFSNLKAVIKDKRFLIIMPSSFTLSFTATAVFFYQYVFVQDKGWSAPLYATFFTAYALTRFVMSIFGGLWVDKFSARKLFRFYLIPMALGLLPFAFMEGIIGALLFLLFAGVTTGIAGTVKTAVLAEVYGVEKLGTIRSLFTMFMVLSTALGPLIIGMLIDYGVPFYGLMLFLLGMLVLATLNAQRIKKVAMVVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK20</accession>
    <name>A0A5C6ZK20_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Chromate efflux transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">chrA</name>
        <name evidence="8" type="ORF">ESY86_05410</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015109">
        <property type="term" value="F:chromate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014047">
        <property type="entry name" value="Chr_Tranpt_l_chain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003370">
        <property type="entry name" value="Chromate_transpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02417">
        <property type="entry name" value="Chromate_transp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004810">
        <property type="entry name" value="ChrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00937">
        <property type="entry name" value="2A51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="80"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="114"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="143"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="207"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="270"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="304"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="335"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD90179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="373" mass="40537" checksum="7FBD599BEFBCC033" modified="2019-11-13" version="1">MSNKKELIEIAKLFFKLGSIAFGGPAAHIAMMEDEVVKKRKWMTQEHFLDLVGATNLIPGPNSTEMTMHCGHERAGWKGLFVAGFCFIFPAVVITSIFAWLYQQYGQLPKVEPFIYGIKPAVIAIIIMAAFRLGKKAVKNTELAILGVITLVACLFGVNEIIALFGCGLLGLIIYFFKKNTRSLKSFIPLLLFQVVDPSKIGTLKMFLTFLKVGAILYGSGYVLFAFLDTELVANGWLTRQALIDAVAVGQITPGPVLSTATFIGWQMNGITGAIVATLGIFLPSFLLVLILNPLIPKMRKSKIIGAILDAVNVAAVALIIAVCVEMAKDTLTDWRTILIAVASLIVVFVFKKVNSAFIVLGGAIIGYVLTFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKA7</accession>
    <name>A0A5C6ZKA7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF368 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007163">
        <property type="entry name" value="DUF368"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37308">
        <property type="entry name" value="PTHR37308"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04018">
        <property type="entry name" value="DUF368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="221"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="255"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="312"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="339" mass="38146" checksum="AB8C97AA5219C715" modified="2019-11-13" version="1">MQQSTRTFTDRFFLIIKGLGMGAANKVPGISGGVVAFVAGFYEEFIYSLKQVNKKAFKLLIAGRFKSFYRYINGRFLGLLFFGMIVSYFSVSKILDYFLSHYELYVWSLFFGMILGSIYYINKSFDDWHYKSIISLIIGAGLGIGISFLNPAKENDNLIFVFFCGIISVSGMTLPGFSGSFILILLGNYVLLLVDSVNSLYDTFAELIVGDFSFIQNTARIRLLKVLAVFTLGSVVGLVTFSHVLSYVLKYYRSITTASIIGFIVGSLGVVWPWKNTIFKTDDDGGLLYDSVGKKIIENYERFLPELNAETYLAFAYIIFGILLVLVLEWYGQKTRTNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKD6</accession>
    <name>A0A5C6ZKD6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Oxygen-dependent coproporphyrinogen oxidase</fullName>
            <ecNumber evidence="6">1.3.3.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">hemF</name>
        <name evidence="6" type="ORF">ESY86_07515</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="4">Porphyrin-containing compound metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.3.3" evidence="6"/>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00660"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004109">
        <property type="term" value="F:coproporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006779">
        <property type="term" value="P:porphyrin-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1500.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001260">
        <property type="entry name" value="Coprogen_oxidase_aer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036406">
        <property type="entry name" value="Coprogen_oxidase_aer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002686">
        <property type="entry name" value="Transposase_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036515">
        <property type="entry name" value="Transposase_17_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10755">
        <property type="entry name" value="PTHR10755"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01218">
        <property type="entry name" value="Coprogen_oxidas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01797">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00073">
        <property type="entry name" value="COPRGNOXDASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01321">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102886">
        <property type="entry name" value="SSF102886"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143422">
        <property type="entry name" value="SSF143422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Y1_Tnp" evidence="5">
        <location>
            <begin position="7"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD89625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="515" mass="59858" checksum="B5BF11D1F9FFE576" modified="2019-11-13" version="1">MKLEKLEKDFYYHIYNRGIHSETIFKNDDNKSYFLNLVGKHISHKVQIIAFCLMNTHFHLVVKVSDENKITEAFSNLFNAYAKAFNKQQHRTGSLFEKHFKRKRLISEDYLKNAILYVHSNPTHAIKEYPFSSYFYYVNGNNPAPFTLDHSEIERVFDSVENLRTLQQASNITSADLQGFENLAGQSSNLHQDHPQDDHNLQGLEDLVGLNEKSTMKTKFYTYIQNLQDRICDKLEAIDGTAKFREDLWDRTEGGGGRTRVIENGKVFEKGGVNISGVHGALPESMQSYFGVKDANFFACGLSLVLHPKNPMVPTVHANWRYFEMYDQDGNIVDQWFGGGQDLTPFYLFDEDARHFHQVCKTACDKHDESFYPHYKNRCDTYFYNTHRNESRGIGGLFFDYCKKTDAMSMQDWYDFVTEVGDSFLDAYAPIVEKRKDLPYTETQRNWQEIRRGRYVEFNLVHDKGTLFGLKTNGRIESILMSLPPHVQWVYDHHPAPGSAEEKLLEVLQNPVDWV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKD7</accession>
    <name>A0A5C6ZKD7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">T9SS type A sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_06065</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010620">
        <property type="entry name" value="SBBP_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007159">
        <property type="entry name" value="SpoVT-AbrB_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06739">
        <property type="entry name" value="SBBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51740">
        <property type="entry name" value="SPOVT_ABRB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022836022" evidence="2">
        <location>
            <begin position="21"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="domain" description="SpoVT-AbrB" evidence="3">
        <location>
            <begin position="168"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD90299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="568" mass="61314" checksum="BB33EE50B07CC645" modified="2019-11-13" version="1">MKKSTTFFAILLLTISTGFAQTIDFVNSFGSLGFERPTGLALDSDKNIYNTGLFLQTVDFDPGSGVFELTSNGSEDIYITKSTPDGTIIWAKQIGGTQSDESSQLTLDDQGNIYLTGTFSGTADFDPSSAVTELTSAGFFDGFILKLDTDGNFIYVKQFSSPISSLRTSTITIDASGDLIVSGRFRDTVDFDPGAGVFELTASTASDGIFILKLTSDGNFVWAKGILGNGQGRIAAIDTDQTGNIIASGEYNNGSRDFDPSSNVFVLATRGIEWAMFVLKLDTNGDLVWAKQITGTAENYGGDVVVDSVGDIYLNGFYQGTLDFDPGSGIFELTSNGSFDIYTMKLNANGDYIWATSVGGPSFDLGINLDITPDNELLNIGIFRGTVDFDSSNDVNEFTALGNQDVFVSRTDANGNYIDTFIYGGPDFDHGFIILTDDVGDYYITGFFGGTSDFDPGMGEVFLTSNGNADGYVLKLNKPTLDITKSNYDNEIQLYPNPVRSVLTIINTSNLELDTAQITDITGKVIMFFNLETMGLTKEISLENFASGLYFVKINTLSGALTKRILKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKG7</accession>
    <name>A0A5C6ZKG7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thioredoxin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="102" mass="11652" checksum="ECE5CE4578800ED5" modified="2019-11-13" version="1">MVQELEKDNLKEIISENDIVMVQYSATWCGNCKIMKPKFKKLATEHENASFVIADAEKFPESRTLAKVDNLPTFALFKNGELVNQVQTNKFDVLKELVAEMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKN2</accession>
    <name>A0A5C6ZKN2_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Argininosuccinate lyase</fullName>
            <shortName evidence="5">ASAL</shortName>
            <ecNumber evidence="3 5">4.3.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Arginosuccinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">argH</name>
        <name evidence="7" type="ORF">ESY86_02220</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>2-(N(omega)-L-arginino)succinate = fumarate + L-arginine</text>
            <dbReference type="Rhea" id="RHEA:24020"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:57472"/>
            <dbReference type="EC" id="4.3.2.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.1" evidence="3 5"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00114"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004056">
        <property type="term" value="F:argininosuccinate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042450">
        <property type="term" value="P:arginine biosynthetic process via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01359">
        <property type="entry name" value="Argininosuccinate_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00006">
        <property type="entry name" value="Arg_succ_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009049">
        <property type="entry name" value="Argininosuccinate_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43814">
        <property type="entry name" value="PTHR43814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00838">
        <property type="entry name" value="argH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4 5" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lyase_1" evidence="6">
        <location>
            <begin position="24"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD90797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="429" mass="48788" checksum="4086781257117EFB" modified="2019-11-13" version="1">MKLWDKGISIDKKIEQFTVGNDREVDLHIAKYDVRASMAHAKMLHNIGILDASELEQLQTGLKVLAEDISEGTFYIDAQFEDVHSKIEFELTKQYGEVGKKIHTARSRNDQVLVALQLYYKDSLNLIQDKTEAFFNSLLKLAETHKEQVLPGYTHLQVAMPSSFGLWFSAYAELLVDDVYLLNAAFKTVDQNPLGSAAGYGSSFNIDREFTTKELQFATLKYNVVAAQMARGKSERTLSMALGSLCNTLSRFAMDICLYMSQNFGFISFPDELTTGSSIMPHKKNPDVFELIRGKCNKIQALQTEMLLITNNLPSGYHRDYQLLKEHMIIAINDVVDILDIFDYAIQQIEVKTIDLNDEKYQYLFTVDNINTLVEEGMSFREAYQIIGKQVQDGTYEPDRSKQHTHAGSIGDLCLEQIKAKFPKREKHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL46</accession>
    <name>A0A5C6ZL46_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA mismatch repair protein MutS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_08220</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS_family"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="PTHR11361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="SSF48334"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_MISMATCH_REPAIR_2" evidence="4">
        <location>
            <begin position="415"/>
            <end position="587"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD89367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="590" mass="66931" checksum="A965B20ED993A2DE" modified="2019-11-13" version="1">MKNPKTYYQQQLEFNTQQATGLKKRLLGLSTLRLIVFMATAIAIYFAWGNYVIMAGIAFVGIALFIVLLVNYNKFKSKKILHEALADINQEELLIIESKFHHRKDGMAYQDTQHFYSWDIDLFGRGSFFQYMNRTATAEGGLQLAQALKANDIKSITERQLAITELSEMADWSQLYAATASLVKTETSAKAIMDWLKNHKPFIPKFMLWFPQVFSVFSIVLFGLCVAELIDFNYFGYWLFVGLLITGRFLKNINTLANNSDKTKNTFKQYASLLDQIEQRSFSSQLLQAKQAQIQSQGKKASAIFKSFSKKLDALDNRSNLISALFGNGYLLLDIKNAYQVERWIGSYAQTVEHWFEAVAFFDAYNSLGTYAYNHQDHVFPELMHNKSAIEAKGLGHPLLNKTKRVTSDLKIDQQQFFIITGANMAGKSTFLRTVSLHIVMANVGLPVCASASKYAPIKLITSMRTSDSLTDDSSYFYSELTRLKFIVDAIVEEPYFIILDEILKGTNSTDKAIGSKKFVEKLVAGKATGIIATHDLSLCSISEALDEVENYYFDAEIIEDELYFDYKLKIGVCKNMNASFLLRKMEIVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLA1</accession>
    <name>A0A5C6ZLA1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">YeeE/YedE family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_04315</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0394 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007272">
        <property type="entry name" value="Sulf_transp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04143">
        <property type="entry name" value="Sulf_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="104"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="Sulf_transp" evidence="8">
        <location>
            <begin position="29"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD90599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="137" mass="14912" checksum="C7639077FE2682CB" modified="2019-11-13" version="1">MKSLKFLLVGIIFGIVLVKSEAVSWYRIYEMFKFESFHMYGIIGTAVLTGILLLLISKKFQFKNIKGAQMQVPAKESGITNYLVGGSIFGLGWALSGACPGPMYILVGTGVFSMLIVIAAAILGTYVYGVLKPKLPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLB8</accession>
    <name>A0A5C6ZLB8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_08630</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="560" mass="61114" checksum="3A6B42FFCCD48F9E" modified="2019-11-13" version="1">MKKVIYLLVMAAAFVGCNPLDDLNDQVDALPEQPNIGEFEYTLTDADYSAFDLGFGSFNSQDQAKDSIPQLLSDLYPLYGQGSSVLVNYKLFVGAAEGVSAYTSAETYPLSNDDYALTGSDAFGFYPNVDPTALIPDVLDAQIAAPVEGQIALVTYKQYTETPDVGLAIVGGGNFPDIYPTFENVDVDMDGIGWSEGAAHANASAFVNGSEIAGEDWLVSPEIDLSGETDLKFQINQRISFLNGNEAADFVNILVSTNYTTGGDPIAATWDVITLTTVPSGNTSEFILSEDYDFSAYDDTVIHVAFRYNSTSTVAPLWRIDYFNIKTLGVTGNTDSKGEYFVYEGGSWNDAENVYYLSNADYDSMGESSGQPGAFNNFSSSTPADSYLPTFLDLKYPFAQEENKIIVIYKYFSSNSGAGIRGNEYTFTSGQWMAHESTIETSLKFGFDEGQWVPDNTIRYIIAQADIDYIATNYASADGFSAAVSSMANFGNFDRRSSNAAFWSVEMLNTVFTDLLTNFLAPNAEEGQKYVLTFDIYDGSSGTEELKYIKTGGVWVPNVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLK9</accession>
    <name>A0A5C6ZLK9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="140" mass="16307" checksum="DFBBE85DDC5F1FE1" modified="2019-11-13" version="1">MVIAIKPPTSFWVVAVFALIWNIVEIYFSSFEIDFLQENLTVEEFENVQSIPFWYAIVFIVTLFSELLGSFMLFMRRKIATTFFAVALIALLFIESYWLFVIDIKKTSMVFALLIPVVVIAVAAFLYFYSKRATKKGWLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLL5</accession>
    <name>A0A5C6ZLL5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">GTPase Era</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">era</name>
        <name evidence="12" type="ORF">ESY86_04135</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 8 9">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070181">
        <property type="term" value="F:small ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04163">
        <property type="entry name" value="Era"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00367">
        <property type="entry name" value="GTPase_Era"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030388">
        <property type="entry name" value="G_ERA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005662">
        <property type="entry name" value="GTP-bd_Era"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004044">
        <property type="entry name" value="KH_dom_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42698">
        <property type="entry name" value="PTHR42698"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07650">
        <property type="entry name" value="KH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00436">
        <property type="entry name" value="era"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51713">
        <property type="entry name" value="G_ERA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50823">
        <property type="entry name" value="KH_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4 6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Era-type G" evidence="11">
        <location>
            <begin position="4"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="KH type-2" evidence="10">
        <location>
            <begin position="201"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="G1" evidence="8">
        <location>
            <begin position="12"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="region of interest" description="G2" evidence="8">
        <location>
            <begin position="38"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="G3" evidence="8">
        <location>
            <begin position="59"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="G4" evidence="8">
        <location>
            <begin position="120"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="G5" evidence="8">
        <location>
            <begin position="149"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="12"/>
            <end position="19"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="59"/>
            <end position="63"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="120"/>
            <end position="123"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TXD90565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="293" mass="33731" checksum="DABE59119E783F14" modified="2019-11-13" version="1">MAHKAGFVNIIGNPNVGKSTLMNAFVGEKLSIITSKAQTTRHRILGIVNGEDFQMILSDTPGIIKPAYELQASMMDFVKSAFDDADILVYMVEIGEQELKDEAFFVKITNSKIPVLLLLNKIDKSNQEQLESQVQLWTQKVPNAEIFPISALEGFNVKEVFERIVELLPESPAFYPKDQLTDKPERFFVNETVREKILMHYKKEIPYAVEIDTEEFFEEETIIKMRSVIMVERETQKGIIIGHKGAALKRVGVEARKDLEKFFGKQVHLELYVKVNKNWRSDQRQLKRFGYNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLS1</accession>
    <name>A0A5C6ZLS1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_01275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="233"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="347" mass="40340" checksum="8AB3AFCCBBC886D8" modified="2019-11-13" version="1">MIEIDIVPEDNKNSLKQILKSIGGELKEDWHQSCLTVDNHLAKGKITCMPFDWGVELIDFEIKFFDDVMIRTKTDTINPLCFMYNLRGHFTHRFGVNNEEKQVEHFHSLIFTNKAEGENFLHFPASEPLDINMIQIKRKDFLKKRTSNVSTLNKRLHEVFVDTDHELRFAHYGSLNLKLGDFIKKIKKTKGQGMVKSLKIEALVYEILSYHIQQHNTFSRGVPLPTSLSQSELKLIRSLGNKIIKEPSFDYSLDQLSSESGLSQAKLQEGFKFLYTRTVTEYVRHIRLQRARDLLNQANLNISEVVYSIGFTSRSYFSKIFKEKYAITPNEYRKKVLKNLVLEKVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLT5</accession>
    <name>A0A5C6ZLT5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleoside triphosphate pyrophosphohydrolase</fullName>
            <ecNumber evidence="2">3.6.1.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">mazG</name>
        <name evidence="2" type="ORF">ESY86_04565</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.9" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036218">
        <property type="term" value="F:dTTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035529">
        <property type="term" value="F:NADH pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004518">
        <property type="entry name" value="MazG_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011551">
        <property type="entry name" value="NTP_PyrPHydrolase_MazG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30522">
        <property type="entry name" value="PTHR30522"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03819">
        <property type="entry name" value="MazG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00444">
        <property type="entry name" value="mazG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MazG" evidence="1">
        <location>
            <begin position="31"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="MazG" evidence="1">
        <location>
            <begin position="162"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="257" mass="29981" checksum="12CBFC2E77217B4A" modified="2019-11-13" version="1">MADKIQQLKAFERLLNIMDELREQCPWDKKQTMESLRHLTIEEVYELGDAILDDDQEEVKKELGDVLLHIVFYSKIGSETDAFDMADVCNGICDKLIERHPHIYGDVKVENVEDVKRNWEQIKLKEGKTSVLQGVPKSLPAMVKALRIQDKVAGVGFDWEQPKQVFEKVQEELQELQVEIDAGDQEKMESEFGDVLFSMINYARFLKIDPESALERTNKKFIKRFQYLEQKSKDSEKKISEMSLAEMDVFWEEAKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLU9</accession>
    <name>A0A5C6ZLU9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="11">ATP-dependent Clp protease ATP-binding subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">ESY86_01450</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the ClpA/ClpB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036628">
        <property type="entry name" value="Clp_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004176">
        <property type="entry name" value="Clp_R_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018368">
        <property type="entry name" value="ClpA/B_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028299">
        <property type="entry name" value="ClpA/B_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001943">
        <property type="entry name" value="UVR_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17871">
        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02861">
        <property type="entry name" value="Clp_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81923">
        <property type="entry name" value="SSF81923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51903">
        <property type="entry name" value="CLP_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00870">
        <property type="entry name" value="CLPAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00871">
        <property type="entry name" value="CLPAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Clp R" evidence="10">
        <location>
            <begin position="1"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="UVR" evidence="9">
        <location>
            <begin position="448"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="158"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="444"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="158"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="175"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD91278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="851" mass="95520" checksum="35BD45984B79EA7B" modified="2019-11-13" version="1">MDDNFSPRVKDVIAFSKEEALRLGHDFIGTEHLMLGLLRDGNGKAIDILAALEIDLNHLRRKVEILSPANSNVVVSSNDKKNLHLTRQAERALKTTFLEAKLFQSSSINTAHLLLCILRNENDPTTKLLNKLKVDYDNVKEQFKFMITNDNDFIDLPKAESFSEDDGRDGDDAKQNPFGQTSTKSTKKSKTPVLDNFGRDLTVMAEDGKLDPVVGREKEIQRVSQILSRRKKNNPLLIGEPGVGKSAIAEGLALRIVQRKVSRILFNKRVVTLDLASLVAGTKYRGQFEERMKAVMNELEKNEDIILFIDEIHTIVGAGGATGSLDASNMFKPALARGEIQCIGATTLDEYRQYIEKDGALERRFQKVIVEPTTVEETIEILNNIKGKYEEHHHVDYTQEAIEACVKLTNRYMTDRFLPDKAIDALDEAGSRVHITNIEVPKQILELEQKLEDVKETKNSVVKKQKYEEAAKLRDDEKRLEKELAIAQEKWEEDTKLHREVVSEDNVADVVSMMTGIPVNRIAQTESNKLAQLPELIKGKVIGQDEAVSKVVKAIQRNRAGLKDPNKPIGSFIFLGQTGVGKTQLAKVLARELFDSEDALVRIDMSEYMEKFAISRLVGAPPGYVGYEEGGQLTEKVRRKPYAVILLDEIEKAHPDVFNMLLQVLDDGYLTDSLGRKIDFRNTIIIMTSNIGARKLKDFGQGVGFGTAAKIAQVGDNTRSVIENALKKAFAPEFLNRIDDVMVFNALEKEDINKIIEIELSQLIARIKDLGYELKLTNEAKEYIADKGFDKEYGARPLKRAIQKYVEDALAEEIINSKLHDGDTILMDTDPDAENEKLKVTIVGSEKESKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM25</accession>
    <name>A0A5C6ZM25_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">1,2-phenylacetyl-CoA epoxidase subunit A</fullName>
            <ecNumber evidence="2">1.14.13.149</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">paaA</name>
        <name evidence="2" type="ORF">ESY86_01950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.13.149" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097266">
        <property type="term" value="F:phenylacetyl-CoA 1,2-epoxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010124">
        <property type="term" value="P:phenylacetate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011881">
        <property type="entry name" value="PaaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007814">
        <property type="entry name" value="PaaA_PaaC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05138">
        <property type="entry name" value="PaaA_PaaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02156">
        <property type="entry name" value="PA_CoA_Oxy1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="318" mass="37044" checksum="9F648A2624B9630B" modified="2019-11-13" version="1">MSEEQVRSLEKQFDERIERDEKIEPKDWMPEKYRKTHIRQMSQHAHSEIVGMLPEGNWITRAPSLRRKVALLAKVQDEAGHGLYLYSATETLGISREEMYEQLHTGKAKYSSIFNYPTVTWADMGTVGWLVDGAAIINQVPLCSTSFGPYARAMVRVCKEESFHQRQGYEIMLKLCKGTPEQKDMAQDALNRWWWPSLMMLGPTDAESVHTEQSMKWKLKRKSNDELRQQFIDQTVPQADILGLSIPDKDLKWNEERQSYDFGEINWDEFWQVVKGHGPMNKERIKARVNAWEGGEWVRDAAMAYASKNQERKEKQAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMA3</accession>
    <name>A0A5C6ZMA3_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L33</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 5" type="primary">rpmG</name>
        <name evidence="5" type="ORF">ESY86_03945</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00294">
        <property type="entry name" value="Ribosomal_L33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038584">
        <property type="entry name" value="L33_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001705">
        <property type="entry name" value="Ribosomal_L33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43168">
        <property type="entry name" value="PTHR43168"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00471">
        <property type="entry name" value="Ribosomal_L33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="SSF57829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01023">
        <property type="entry name" value="rpmG_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="60" mass="7066" checksum="FA9B09E37E5C20B7" modified="2019-11-13" version="1">MAKKGNRIQVILECTEHKESRQPGTSRYITTKNKKNTPGRMEIKKFNPILKRMTVHKEIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMG9</accession>
    <name>A0A5C6ZMG9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF721 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_00705</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007922">
        <property type="entry name" value="DUF721/UPF0232"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05258">
        <property type="entry name" value="DciA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="98" mass="11053" checksum="EEB8344E62752501" modified="2019-11-13" version="1">MARRNNDNQSISDILKEFVDSNRLQSGLNKVDVQDAWAKMMGNGVNNYTTAVQLDKDTLYVSLSSSVLREELSYGKQKIIDMLNESLGKEVISKLVLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMH0</accession>
    <name>A0A5C6ZMH0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DegT/DnrJ/EryC1/StrS family aminotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_02600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the DegT/DnrJ/EryC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00616">
        <property type="entry name" value="AHBA_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000653">
        <property type="entry name" value="DegT/StrS_aminotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30244">
        <property type="entry name" value="PTHR30244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01041">
        <property type="entry name" value="DegT_DnrJ_EryC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000390">
        <property type="entry name" value="PLP_StrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="192"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD90868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="384" mass="42407" checksum="BC7DC4A7016F2DEF" modified="2019-11-13" version="1">MKTIQMVDLKGQYSKIKEDVDASVLEVLDSTAYINGPKVHQFQKNLEAYLGVKHVIPCANGTDALQIAMMGLGLKPGDEVITADFTFAATVEVIALLQLTPVLVDVDEVTFNIDIDAIKKAITPKTKAIVPVHLFGMCANMEAIMAIAKEHNLFVIEDNAQGIGADYTWSNGKKSKSGTIGHVASTSFFPSKNLGCYGDGGAIFTNDDDLAHIIRGIVNHGMYERYHHDVVGVNSRLDSIQAAILDIKLKHLDTYNKKRQNAARAYNKAFKNEEHIVIPTGRDVCSGICDTCDCHVFHQYTLRILNGKRDALVKHLNENGIPCGVYYPIPLHLQKAYTDSRYIESDFTVTNRLIAEVISLPMHTELDDEQIAFIAATLKNFINA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMN4</accession>
    <name>A0A5C6ZMN4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Crp/Fnr family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03005</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="1">
        <location>
            <begin position="8"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="188" mass="22080" checksum="607133600859A8C9" modified="2019-11-13" version="1">MITDFLINFVPFSHDELNDILPYFKKEKVKKNEVLIKEGQVCSKLYFVDQGIGRSYYLKKDGKEVTQWFFGVNNFMSSVDSFFQQSPSFYYLEVLEDSILYSITKKNMDALLAKYHNMETFIRLLTIDTLAKFVHKLNAIQFQTAKERYTYMLAEFPDISHRVPLGHIASYLGITQETLSRIRKNDSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMP8</accession>
    <name>A0A5C6ZMP8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Baseplate_J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006949">
        <property type="entry name" value="Baseplate_J-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04865">
        <property type="entry name" value="Baseplate_J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Baseplate_J" evidence="1">
        <location>
            <begin position="792"/>
            <end position="966"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1052" mass="120975" checksum="FC1CD4B3409B1D9A" modified="2019-11-13" version="1">MANCNTQIEIHRQPGATQASRFPKGLSTDFVLLDERSIQDLIVSTIQLSKHIHFYGAENVIDGNWSALFSWESTSLFAELSTLNVKALQQELKLKLRKLLFIADEADRKSEMRVFFQAIQNQLTEYHSRMVKLPEAISIKEYYLSFYIRVNELMVYIMDQIDLSTDALQLFHDHLFNKQVRNLFGMLLDLKTKSGSSFQEQIDSYPKHSPQYTLFLTFLKLFSEAQKEANQFTTRHLDFYYKKILRLEANSAEPDFVHCIVQSHKNIDPFLLEKNAVLLAGKTDDGKAKYYAATSDLAVNHAKIDQVFGGFLENKTNFDQYYFHDFTELITAGEAWKPFEKHTASHTIGFALASPLLFLKGGDRKIKLSFENGWTNFNYQSLKDKFNFYLTAEEEWIEVNEYVGVNNMVIITLPAEISPIIPFNSDFHDGVTIDTTFPILKIIAKNGQLIQKAINAFILEVEVNNYKEFSLFSDFGEIDHSKKFEAFGPIPRKESSIYFSSNEFFQKKNAIGNFEIKMDDLSWNIFEHTTINLLNKGTWGTIDLDNPITNTNEIKEREFTYDENPAFNKKTVHGIARIKFINYDFSDSKSGTNSYLEIFIDAGKDKVNTNLPYLPIITDFSFRYSADSNDNEVQTFHLYPKGYEAKSLRELLPKFENEGELIVGIKDVKAGQPLSLLIQVEEGSADPTLAPAEINFRYLDQQNVWSEFDEDIAGDETNGLTQSGIIFFKVPKEFQFSGQTIFTESIFWLRIAVPQRTAAVCNLVGLHLQAFKAVLTDYENTGVLFTKHLESKTITKLLRPKNQIKKIEQPYSSFGGRAKDTDSDFYKRTSERLRHRTRAISKWDYETLVLDEFPQVHRVKCLPHYQVKSDRVNNTSAGNVTIVPVAASTNENLPVAWRPLVDLNTMKRIKLFLQNHATPHAKIDVIPPNLEHVRFSFQIKYHDAINADTRLYQESLNGIINAYLSPWAYKTQENVQFQNEIYTSKLIQIIESQNFVDYIFDFKAKHYDEDLTDAAKASKTFKAMDKIVPLTDYSLFLPGEHLIQESNSLCCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMT2</accession>
    <name>A0A5C6ZMT2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_07045</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="282" mass="31897" checksum="48734164A1B5EADC" modified="2019-11-13" version="1">MRTELFRDRKLVIATKHSKEKVIAPLLEQALGVFCFVQDGFDTDTLGTFTGEIERELDPISTARQKCLMAMEASNCDLGIASEGSFGAHPSMFFVSADDEFLIFIDKKNNLEIIARELSVETNFNGSEINNEQELMDFADLIKFPSHGLILRKSKTDNSDIIKDITNLQDLKKAFHLLIEKFSPVYAETDMRAMYNPSRMNVIENATRKLVDKINSCCPQCDIPGFGVTDVKKGLECNLCGSPTNSTLSYSYVCQHCQFIKEDMYPHKKTTEDPMYCDYCNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMU2</accession>
    <name>A0A5C6ZMU2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">T9SS type A sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_05815</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022920064" evidence="1">
        <location>
            <begin position="19"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="Por_Secre_tail" evidence="2">
        <location>
            <begin position="81"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="156" mass="17031" checksum="0FCD72E2C00B96DD" modified="2019-11-13" version="1">MKNLLPLFIFLLVTMSYAQKDIVSSGGNAIGTGGSVDYTVGQVAYQTKSNTNASMLEGVQQPVEIYALSVTGVETAINATLYPVPATTLVNLKLNLTKFSGTPRFEIVDINGRILSQSSISANHTQIDISHLETANYFFNIVLNKKRIKTFKLIKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN10</accession>
    <name>A0A5C6ZN10_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_02395</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="74" mass="8630" checksum="84B49C02844B0170" modified="2019-11-13" version="1">MKLNKEIKNRIDQYFENISSEELYFKAIGKYGFNEDIDFEIDNQFFDNAGQNFYCPNSDNSLDANDMESLLLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN25</accession>
    <name>A0A5C6ZN25_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_01640</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="164" mass="19045" checksum="C92975BDE457CDC6" modified="2019-11-13" version="1">MIKIKVSEQDKLFAKQQIEAFQKIDAGSWRYANVEAWRGIVCELLASQWFEQHFKIDKPAKGLDNSGIVDDCDMIINAKKIEIKSATKNFFRYLMPKIHDVRNHPKDIYIGVKYNETVEPNEIQILGHIKRAQILEFPIKKNKGAPYYEVPLSQLAPIDQHTFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN37</accession>
    <name>A0A5C6ZN37_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_01690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="81" mass="9369" checksum="DE4F8F3F0FF20B28" modified="2019-11-13" version="1">MKFTKYKRTQIAEMRPATKEEIELGRLIVTKTHSRKAISVSEADLQNGSPKSGDMIARNPKNHDDQWLVAKQYFEDNFESL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNL0</accession>
    <name>A0A5C6ZNL0_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Na(+)/H(+) antiporter NhaA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Sodium/proton antiporter NhaA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 8" type="primary">nhaA</name>
        <name evidence="8" type="ORF">ESY86_02810</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>2 H(+)(out) + Na(+)(in) = 2 H(+)(in) + Na(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:29251"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015081">
        <property type="term" value="F:sodium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006885">
        <property type="term" value="P:regulation of pH"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01844">
        <property type="entry name" value="NhaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023171">
        <property type="entry name" value="Na/H_antiporter_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004670">
        <property type="entry name" value="NhaA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30341">
        <property type="entry name" value="PTHR30341"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06965">
        <property type="entry name" value="Na_H_antiport_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00773">
        <property type="entry name" value="NhaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0050">Antiport</keyword>
    <keyword evidence="3 7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0915">Sodium</keyword>
    <keyword evidence="7" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="153"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="183"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="216"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="302"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="332"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="372"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="406"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD90904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="442" mass="49624" checksum="138ACA829DB330A5" modified="2019-11-13" version="1">MANLTQSFNNFFKKDSAPGILLIVATIAALIVANTPLKHFYTELMHIKFSMGFDEIYLSKSLHHWVNDFLMALFFLLVGLEIKSELKFGGLRTFKSAIFPVVAAISGALFPALIFIAFNQGTDYIKGWAIPMATDIAFVIGIIAMLGSRMPSWAKVFITTIAVVDDLIAVLVIAFFYTDDIRWQALGIAGICTLVLLFLNYKNVNRLTPYLAVGFILWWAVLASGIHATIAGVILAMTVPLRREWRLGRIKAFARKGFKLFKRAKDSTLAMTTPEVHRYLENTQREMESPLKRLERKLHAPVYFFIMPVFAFVNAGIVFNSEILNEAFHLPITWGTILGLSVGKPFGVLLAIWILLKFFYKNMPQTPEIWKLLMGISLLCGIGFTMSLFIVNLSFMDEVVREEAKIGILLASLLNGVLGYWVLHDATKKPEAITADKINITR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNY3</accession>
    <name>A0A5C6ZNY3_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ornithine aminotransferase</fullName>
            <ecNumber evidence="3">2.6.1.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Ornithine--oxo-acid aminotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rocD</name>
        <name evidence="7" type="ORF">ESY86_00840</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-ornithine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.13" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00358"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050155">
        <property type="term" value="F:ornithine(lysine) transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004587">
        <property type="term" value="F:ornithine-oxo-acid transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010164">
        <property type="entry name" value="Orn_aminotrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11986:SF18">
        <property type="entry name" value="PTHR11986:SF18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01885">
        <property type="entry name" value="Orn_aminotrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4 6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD91167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="426" mass="46784" checksum="F7E7B9856976289C" modified="2019-11-13" version="1">MAVTDQITSQQAIDLENKYGAHNYHPLPVVLNRGEGVHVWDVEGKQYYDFLSAYSAVNQGHCHPKIVNAMHEQAKTLSLTSRAFHNDILGKYEKYAAEYFHFDKLLPMNTGAEAVETALKICRKWAYEVKGIHENEAEIIVCENNFHGRTTTIISFSNDTVARKHFGPYTEGFIKIEYDNLEALKQALEGNKNIAGFLVEPIQGEAGVYVPSDNYLIEAKALCEKHNVLFIADEVQTGIARTGRLLATCGNCDCADKNCSGTPDVKPDILILGKALSGGAYPVSAVLANDAVMNVIRPGNHGSTFGGNPIAAAVAMAALEVVRDEDLAENAFQLGELFRSEINKYIETSNIVNLVRGKGLLNAIVINDDEDSDTAWNICIALRDNGLLAKPTHGNIIRFAPPLVMTKDELLDCVSIITKTLKDFEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZP63</accession>
    <name>A0A5C6ZP63_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type VI secretion protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_00510</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008727">
        <property type="entry name" value="PAAR_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05488">
        <property type="entry name" value="PAAR_motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="97" mass="9258" checksum="026460A5B310A497" modified="2019-11-13" version="1">MSLAARLNDMHVCPMANPNGSPHVGGPILPGSNATVLIEGLPAACMGDQCTCAGPPDVIVAGSGSVLIGGKPAARMGDSTAHGGSIVIGAGTVLIGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPC8</accession>
    <name>A0A5C6ZPC8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DNA gyrase subunit A</fullName>
            <ecNumber evidence="8">5.6.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 12" type="primary">gyrA</name>
        <name evidence="12" type="ORF">ESY86_01445</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP-dependent breakage, passage and rejoining of double-stranded DNA.</text>
            <dbReference type="EC" id="5.6.2.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Heterotetramer, composed of two GyrA and two GyrB chains. In the heterotetramer, GyrA contains the active site tyrosine that forms a transient covalent intermediate with DNA, while GyrB binds cofactors and catalyzes ATP hydrolysis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="8">Few gyrases are as efficient as E.coli at forming negative supercoils. Not all organisms have 2 type II topoisomerases; in organisms with a single type II topoisomerase this enzyme also has to decatenate newly replicated chromosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the topoisomerase GyrA/ParC subunit family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the type II topoisomerase GyrA/ParC subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.2" evidence="8"/>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034335">
        <property type="term" value="F:DNA negative supercoiling activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00187">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.268.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.199.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01897">
        <property type="entry name" value="GyrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005743">
        <property type="entry name" value="GyrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006691">
        <property type="entry name" value="GyrA/parC_rep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035516">
        <property type="entry name" value="Gyrase/topoIV_suA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013760">
        <property type="entry name" value="Topo_IIA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013758">
        <property type="entry name" value="Topo_IIA_A/C_ab"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013757">
        <property type="entry name" value="Topo_IIA_A_a_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002205">
        <property type="entry name" value="Topo_IIA_dom_A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03989">
        <property type="entry name" value="DNA_gyraseA_C"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00521">
        <property type="entry name" value="DNA_topoisoIV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00434">
        <property type="entry name" value="TOP4c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101904">
        <property type="entry name" value="SSF101904"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56719">
        <property type="entry name" value="SSF56719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="TOP4c" evidence="11">
        <location>
            <begin position="10"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="826"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="434"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GyrA-box" evidence="8">
        <location>
            <begin position="523"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-tyrosine intermediate" evidence="8">
        <location>
            <position position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TXD91277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="854" mass="96241" checksum="6E5CEF19E51EBD11" modified="2019-11-13" version="1">MQQEEKLIPINIEDEMKSAYIDYSMSVIVSRALPDVRDGLKPVHRRVLFGMHELGVRSNTAHKKSARIVGEVLGKYHPHGDTSVYDAMVRMAQEWSLRYMLVDGQGNFGSIDGDSPAAMRYTEARMHKISEEMLADIDKETVDQKLNFDDTLHEPTVLPTRIPGLLVNGASGIAVGMATNMPPHNLTEVIDGTIAYIENNDIEIDELIQHIKAPDFPTGGIIYGYDGVREAFKTGRGRVVMRAKAIIEEVQGKECIIVTEIPYQVNKADMIKKTADLVNDKKIEGISLIRDESDRNGMRVVYILKRDAIPNIVLNMLYKYTALQSSFSVNNIALVKGRPQLLNLKEMIHYFVEHRHEVVVRRTKYELRKAEERAHILEGLIIASDNIDEVIALIRASSNAEEARGKLIARFELSEIQAKAIVEMRLRQLTGLEQDKLRTEYEELMKTIEDLKDILDKQERRYDIIKEELLVIKEKYGDERRSVIEYAGGDLSIEDMIPDEQVVITISHAGYIKRTSLAEYKTQNRGGVGQKASTTRSEDFLEYLFVGTNHQYMLFFTQKGKCFWMRVYEIPEGSKTSKGRAIQNLVNIEQDDKVKAFICTQDLKNEDYINSHYVIMATKKGQVKKTSLEQYSRPRTNGINAITIKEDDELLEAKLTTGNSQVMLALKSGKAIRFEEAKTRPMGRNASGVRGIRLANDKDEVIGMIAIEESQEESVLVVSEKGYGKRSYIDDPEDGEAVYRITNRGGKGVKTISITEKTGHLVAIKSVTDEDDLMIINKSGIAIRMAVNELRVMGRATQGVKLINLKGNDSIAAVAKVMKDEEEIEDDILIDDTIDTTDSQDDGTDVDDSSNEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPM4</accession>
    <name>A0A5C6ZPM4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Long-chain fatty acid--CoA ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_01535</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020459">
        <property type="entry name" value="AMP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00154">
        <property type="entry name" value="AMPBINDING"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="23"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="607" mass="67707" checksum="422F4636B94E8AA1" modified="2019-11-13" version="1">MTRLFDLLDYQLKNNPLEASISGRNKDGNWESYSTQKLKDTAEQAAAGLLKLGLVPGDKVAIVAYKNRPEWVVMDYAVQLAGMISIPLYPTISVLEYEYILNEAEVKAVFCGGLDLYDKLSKSQKEVATLKHIYTFDGLNGNPYWEAIFDTNGISSLESIKSNIKGDDLVTIIYTSGTTGRPKGVMLSHANVMHVVTATAKLLVAGPNEKVLSFLPLCHIYERAVSFCYCYKGVSVFLCGTDNLSGPDGDLAAVGPVAFTTVPRLLEKIYEAIYNKGLALEGTKRKLFFWALDLTDDYELDQQLSFVEKLKWKLADTLIFSKWRAALGGNIKQIVTGAAPCPVKILRVFCAAGIPIREAYGLTETSPTLTANSLEPNAAMIGTVGYAIDGVELYIDKTSGEYKEDEGEILAHGPNVMLGYYKKPEINEQVFQTIDGKKWFCTGDIGKLIKGVDGREFLKITDRKKELLKTSGGKYVAPAPIETRIKEDFLVEQMMVIGDKQKFISALILPSEEALKNWCLHKKMEWTSLAEMIQHEKVIKKYQKVIDSYNPEFGHIEQIKKFKLIATPWLPIHEDGALAELTPTLKLKRRVIREKYSAEIAAIYAKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZQ82</accession>
    <name>A0A5C6ZQ82_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">(Fe-S)-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004017">
        <property type="entry name" value="Cys_rich_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02754">
        <property type="entry name" value="CCG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CCG" evidence="1">
        <location>
            <begin position="22"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="CCG" evidence="1">
        <location>
            <begin position="148"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="263" mass="28951" checksum="B3E1D89AA51BE75D" modified="2019-11-13" version="1">MSEQLNVPTMAEFMAAGKKPEVLFWVGCAGSFDDRAKKITKAFVKLLHRSKVEFAVLGTEESCTGDPAKRAGNEFLFQMQAVTNIEVLNAYEIKKIVTACPHCFNTIKNEYPGLGGSYEVMHHTQFLKSLLDEGRLTIEGGQFKGKRITFHDPCYLGRGNGVYEAPRELIRKLDAELVEMKSCKSRGLCCGAGGAQMFKDAEPGDKEVNIARTEQAIDVKPEIIAAGCPFCNTMMTDGVKNKEREADIAVMDIAELIANAQDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZQH5</accession>
    <name>A0A5C6ZQH5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF1015 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_00930</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008323">
        <property type="entry name" value="UCP033563"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36454">
        <property type="entry name" value="PTHR36454"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06245">
        <property type="entry name" value="DUF1015"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF033563">
        <property type="entry name" value="UCP033563"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="412" mass="47924" checksum="02D9FF80F70A87EB" modified="2019-11-13" version="1">MATIIPFRAVRPTRDKVSLVAARSYQSYTLEQLEARLRDNPFSFLHIVNPGYKYDKVISGQERYNLVRNRYLEFKEDHIFVQDAQPNYYIYKIVDRDRQEFNGIVAAASALDYEKDTIKKHEDTIEPREVVFKDYLKTVGFNAEPVLLTYPDNTIIAEVIEATQTERAEFEFTTTYRDTHYLWKVSDAATVAKIREEFKAMPTIYIADGHHRSSSSFLLYKDEKERNPNHKGDESYNFFMAYLIPESDLKIHEFNRIVKDLNGLTKEEFLIELDTIYRIENRGNMPYKPTQKHHFSMYLDGEFYSLYLRKTGYTIETSLDALDAQILYKTILQPILGIEDLRDDARIAYVNGKKDVINVKSSIDSGSYAVGFGMVPVDIEEIKQIANEGLKMPPKSTFIEPKLRSGVTIYEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZQH6</accession>
    <name>A0A5C6ZQH6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_02630</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="273" mass="31945" checksum="FE135140098EB3B1" modified="2019-11-13" version="1">MAITKVLITVKTYPSLSARYGELVCTAGFLEDGTWMRLYPIPFRKLKYDEKYKKYQWIELDIVKNNKDFRPESFRPATIDTPITLLDTIDTKGNWYKRKQIALKNVHKDIKALIDEAHDKEICTSLAVFKPTKVLDFKIEKVSSEWDKKKIDQQKALNDQGNLFEMEELPFEVVEKLPYKFSYVIEDENGVSSTMMIEDWEIGQLYRNTLAAAEGNEAIAVQKVKEKYFDYFALKRDLYLYLGTTKAFHYRSKNPFMIIGTFTPNIETQTSLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZQZ2</accession>
    <name>A0A5C6ZQZ2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RimK family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_01645</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013651">
        <property type="entry name" value="ATP-grasp_RimK-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025839">
        <property type="entry name" value="RLAN_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08443">
        <property type="entry name" value="RimK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14401">
        <property type="entry name" value="RLAN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="2">
        <location>
            <begin position="286"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD91313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="481" mass="55234" checksum="3D8CDC29401D1CC8" modified="2019-11-13" version="1">MKKFIVVNKLENWNFSTHNIKVITSQDYLTNPEFSTLKKARVFNLCKDYSYQSKGYYVSLLAEARGHLPIPNIRNIVDLKALKLVRIVSDEFDDVIQQSLKNIKSQEFILSIYFGQNVAQKYRELSALFYKHFQVPFLRVKFVHTTKWNVQHIKAISEAEIPKEHVESIQIFADEYFSKKRYDTPKITATDFDLAILVNPNDPAPPSNPKALKRLMDIAEKMNIYTEILEPKDLSRLSSFDALFVRQSTEVNNEAYTFVRKAQQEGLAIIDYPDAILKCCNKVYMAEALENIKVKTPKTLIVHKENKSSALEKVGLPCVLKSPDSTFSFGVKKAKTAAEFDTLVSEMLKESDLIIAQEFCPSDYDWRIGILDNEPFFACKYYMAKDHWQIYNWGSEKKDDQLGNADCLPIEDVPKKVMKMALKSAKLMGLGLYGIDIKVIDDEPMVIEINDNPNIDAGVEDAFYGDEIYIKILNAFKKRLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZRF9</accession>
    <name>A0A5C6ZRF9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_00915</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="412" mass="48281" checksum="B284E63195331E53" modified="2019-11-13" version="1">MFADKNSGICVNQFNQRYQRSIFGTQMTQIWQMFADKNSGIHANQFNPRHQRSVFGTQMTQIWQMFTDINSGISINQFDTHHQRSIFGTQTTQILQMFADINSGISVNQFNPRYQRSVFGTQMTRIFQMFTDINSGIRANQFDPRHQRSVFGTQTTQIFQMFTDINSGIRVNQFDPRYQRSIFGTQITQIWQMFADKNSGICANQFDPRYQRSVFGTQMTQIWQMFTAKNSGISVNQSHLRYQRSMVGTLMMQIWQMFADINSGISVNQFDPRYQRSIFGTQMTQIWQMFTAKNSGIHANQFNPRYQRSVFGTQMTQIWQMFADKNSGIRANQFDSRHQRSIFGTQMTQILQMFTDINSGISVNQFDPRYQRSIFGTQMTQIWQMFTAKNSGIRANQFDPRHQRSIFGTQIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6Z9T4</accession>
    <name>A0A5C6Z9T4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Pyridoxal phosphate-dependent aminotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_20535</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000085">
        <property type="protein sequence ID" value="TXD86186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000653">
        <property type="entry name" value="DegT/StrS_aminotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01041">
        <property type="entry name" value="DegT_DnrJ_EryC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="81" mass="9208" checksum="FC00B01FCF21D3CE" modified="2019-11-13" version="1" fragment="single">VLTPSEEVREGLRKHLESLNIESRPFWRPMHLQPVFKDAPAYVNGVSKNLFKKGLCLPSGSNLSEADLNRVINGIKDFFRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6Z9T7</accession>
    <name>A0A5C6Z9T7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19905</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000051">
        <property type="protein sequence ID" value="TXD86573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="92" mass="10471" checksum="1152588B125FE7A2" modified="2019-11-13" version="1">MKKFEVYKNIRKRAVIFGLPISLFALMMVAILASLLIIIFSFSFLMIIGVMVFNAALYIALTRMANNPQLFQSAKAFPKIISNKRNSGFNYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAI1</accession>
    <name>A0A5C6ZAI1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GLPGLI family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19675</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000045">
        <property type="protein sequence ID" value="TXD86643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005901">
        <property type="entry name" value="GLPGLI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09697">
        <property type="entry name" value="Porph_ging"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01200">
        <property type="entry name" value="GLPGLI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022800760" evidence="1">
        <location>
            <begin position="21"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="280" mass="33116" checksum="A75EE9F0FA41C6E4" modified="2019-11-13" version="1">MKIYKYLIIGLFSIPFFLFSQENQINNSNDVGSVEYIFKIPAEKTIYKTAFLKFNDSISNFIYNKIGMESSRKTGIDSDGSSINVNFSVSDEQGAIVHRNFKSKEIRTRIATIRKLFESYYYDDNWIEIEWEIKGKIKKIGEFTAQKAIGKFRGREYTVWFTEEIPLPYGPWKLFGLPGLILEAEDSEKMFEIKFVSIKYPCNDCELDVSKPTAKEEKTLKEYVEFRDNYNDYVYRKMKSRLPRNLAKNFRKGPQKNNGRKYRDEKVFEWETETIDDKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAW1</accession>
    <name>A0A5C6ZAW1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Toll/interleukin-1 receptor domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000036">
        <property type="protein sequence ID" value="TXD86852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003953">
        <property type="term" value="F:NAD+ nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019677">
        <property type="term" value="P:NAD catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13676">
        <property type="entry name" value="TIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="SSF52200"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50104">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0675">Receptor</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TIR" evidence="1">
        <location>
            <begin position="121"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="281" mass="32671" checksum="E397860E967D9A22" modified="2019-11-13" version="1">MNIQTERKIELLNKLIEKSQEIQSESDSNPKFKSWKNLVERTFVKLFGDKSVEVKQLNTLEFHYQGMRIGGQDYSQTHRNYYKRSFDTLIQSIENYLEEFKEELGTIPEIKENNELEDNNTITKVFISHSSKDSAIVEEVIEILESIGLNSTQIFCTSFNGYGIDYGDNFLERIKNELDNNVLVLFILSENFYQSPVCLCEMGATWMKTNTHIPILIPPMSFKDIKGVIPLTQGFVINDSSALTQFKGQIENVFNIENILNNSTWERKRDRIVNRINKEIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZB05</accession>
    <name>A0A5C6ZB05_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_17810</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000028">
        <property type="protein sequence ID" value="TXD87170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase" evidence="2">
        <location>
            <begin position="458"/>
            <end position="748"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="761" mass="87429" checksum="1BEA470402C2DDAE" modified="2019-11-13" version="1">MDSVFYRENRKSIIRISTLILVFIISHSIFGQNIVIEGVIKGSEQKEALPYANVFLQKNYFGTVSNQNGKFKIIIPEEKSSDSLVISYIGYKTQKFSISNIKNPLVVFLIEDLATLNEVVITGYTAESIIKKAIEKIPSNYFIKPYLSEGFYRATAQKENSFIHLSEAVFEIYQSKIDKPRQQFKLEKMRAIKDEKMLKGVYVGAKPNGIYGFDIVNNLDDMDLLNKKGFRRHNFEVEGSELINGKEAYKISFDQKDIKKAGYKGYMLIDKESFAFVYFNYGFSQKGISYHKYGDVATRLLMKIAGVDIGLNSNSVSITYKKIKNKYYLNNVGYAETITMKSEREHYNFTTDTRVDYLITKIKTDSISPFSDDETLGNGKLIEDQTSIYDTAYWKNYNILLPTNDFTEIARKLEANNKANDFKVELEDKIYKLPKDKTIRIDSILSFYNQKDLFNGNALISYEGQTIFQKSYNNDLTSNNVNSQFRIGSLSKTFTSMIIAQLENENKLNYSDEIEKFLPTYPNGNVTISQLLSHQSGIPNFLSNKSYLPQILTNKYSIEEVVTLFCSDTLEFESGSKFEYSNSNFVILSLIAEKIIEKKYKEILNQYIFKPLNMKNTYFGKSTDSINLVTGFMYGNPEIKYDAQNVGGAGGITSTTSDLLKWSNAFSDEQLLPQSKLENLFKPQAEYTDWDAYYGYGWMIDRFMFSSSKKNKINYHPGTDFGFYSMFVKQPDLGITIILLNNTGEFPRFEMTELILNELNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZB35</accession>
    <name>A0A5C6ZB35_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19320</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000039">
        <property type="protein sequence ID" value="TXD86760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="152" mass="17073" checksum="3040A8B91E721B8F" modified="2019-11-13" version="1">MKFGLNKLKSVFGAKSATEEVAHEVNTDAIIDEIKNVPFGVSENNVLYAGLNELGGYYFFQTVVVGSFRIKTKKGATLKVIGTNFEMTLRGDMDEFESEAAGVPNRYVTNIDFQIDEKDTAKLEKSMLQQLTLNCKKQQLVFKVLETMDEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZB63</accession>
    <name>A0A5C6ZB63_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19665</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000045">
        <property type="protein sequence ID" value="TXD86641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="165" mass="18849" checksum="792272C2788CA6F0" modified="2019-11-13" version="1">MNNNKFKITVILTLIPTLVMANAGSPMMWFGILHSLILNSLIGFYESNYLEKREISNRMWLIIIGNYFSMFIGLYFIAPYFSSISGNIDFWGGKTSYGNYELNGFIFGMLASFIAALILEFPFYYLSVKDKTKRKKGTWIFIEANAISNTVMFLIYLMIVVGGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBQ0</accession>
    <name>A0A5C6ZBQ0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Carboxypeptidase-like regulatory domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_20480</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000079">
        <property type="protein sequence ID" value="TXD86232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="299" mass="34597" checksum="14D576024DC27555" modified="2019-11-13" version="1">MKKLPPLIILLISNLGFCQLKAVIIDSETKEKVPYVNIWVENENIGTTSNEIGVFSIDTSIGKFLILSSLGYENKRIEISTISDIILLQPKLTELDEVVLSSIKKQNEIVIGKFNDSDIGYYYASLDKPEMKARFFPFDSTYYKTPYLKKLKFRIYSEIRNAKFNIRLYSIGNDGKPKNPIYEKNIIGTVKKGTNNVELDLSNLEIIFPETGFFISYEWLIIKDNSYKTTFPIKDSKKRIEKIMYEPKVGFLPSEIDENSWTYKDGNWERVESFTEESNSPQRYINKFGLLAIEMTLTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBU4</accession>
    <name>A0A5C6ZBU4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Abhydrolase_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20075</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000056">
        <property type="protein sequence ID" value="TXD86498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Abhydrolase_3" evidence="1">
        <location>
            <begin position="102"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="303" mass="34860" checksum="55018E23F7926CD5" modified="2019-11-13" version="1">MQKYIIILALITMSCKGQNEKPKSTEKSTPEIIKTSEFELIKPENQKGLLILFPCFPCDADNTLNEFKISEISVKNGFSVLAMNLNELLFLKPKEKQKLAEQLTKIVSEYDLPKKNIFVGGFSSGGNVSLTICDYLVKTKSQIQPKGVFIVDSPVDLLGLYRTAEKNLKLNFSESSVAESKWIKEMLDSEFGNPENGIANYELKSPFTLETQNIENLKGLEKLKIRFYTEPDLKWWKEHAKNDYKDLNAFYIQKLSEQLKTEFGKNNVELIKTENRGYRKNGERHPHSWSIVNEKDLVNWMTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC83</accession>
    <name>A0A5C6ZC83_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19970</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000053">
        <property type="protein sequence ID" value="TXD86529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="179" mass="19471" checksum="AF14EA3F11B40860" modified="2019-11-13" version="1">MKNLLLLLTITLTLSCCKKDDDQSENPIDQLPPATQTGEQTFGCLINGEAFVPPSFGSNSPSAFYQFVDGAYTLSIYGSISGGPNLKSINIGCLDMPLIQETNYTLRERITNNYFGNYNIGGGITYSGSSSTEYPGTLVITNFDPDNFIISGTFEFTVLDSDGGEINITNGRFDMNYTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCB7</accession>
    <name>A0A5C6ZCB7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000046">
        <property type="protein sequence ID" value="TXD86623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011652">
        <property type="entry name" value="MORN_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07661">
        <property type="entry name" value="MORN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023048366" evidence="1">
        <location>
            <begin position="18"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="151" mass="17088" checksum="F6DBD3BA375E8793" modified="2019-11-13" version="1">MKIIILLVCFFPFIACAQSDSISVPPESEMVSMNDTKVKYGGQYGQRYFANGSKVPYTGFLYASYDNGKLESVQQFVDGIGNGIWIDYAPDGKKVGQGTLIDNRVEGPVTFFYEDGSIKSKGKYLDWKRPIGLWTFYDRKGNIVSTRRYTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCP1</accession>
    <name>A0A5C6ZCP1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_17605</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000027">
        <property type="protein sequence ID" value="TXD87250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="112" mass="11947" checksum="EBE37DD35D22429C" modified="2019-11-13" version="1">MKTIHTILISGASGKFSAISGLDDHAKKSGSVILKNVVFQPQTNLWAGYGTPLDNEGTVLIEEKNEAGESLKTWKLSNAKATKFSTGDSIDGAGPSFESIELSYDGIEVETR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCQ8</accession>
    <name>A0A5C6ZCQ8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_17590</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000027">
        <property type="protein sequence ID" value="TXD87247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011495">
        <property type="entry name" value="Sig_transdc_His_kin_sub2_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07568">
        <property type="entry name" value="HisKA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="510"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="domain" description="HATPase_c" evidence="2">
        <location>
            <begin position="662"/>
            <end position="759"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="761" mass="87243" checksum="C9BCF883D8E4EED6" modified="2019-11-13" version="1">MHRIQNLNRFNVTTLKNLRTNRLLFRDFIVKIINVQINGTRKTIPCTCIKSIILCAVILFYSNGFSQSSHIENNTPKNALALSDNYSKKASWFTNMLQFNTNSSLFYAHKALKVLESGEPLHQSKPYGLQFKKKNIEQNLSSEQVAALSKAYQDKALWFKEMPHFNRDSTVFYFDMAALLLQNSQPLQYDGLAELYRDITDRANRSHNFNIVDSLAPIGWAYYEKIPESKKDKVLGYDLLINWALIKIIRGEPKPGLELFEKALDLLKDDSRPEIQLKIMKDKARFYYQYGLPEEEEIAIQYLKESMIGYQKSDYPEKKESLVMAYKLLTYHFGDSNPDSTDYYMNQFQQLLPQLTNPFHHTWYYYSMGNNLIKRENYEEAKSYLIKTIQLLEEYDLTTIDTYQFAHSRIGDIAKAEGSYGEAIAYYEKAKNSSMAINTKANTAYFIKKLFSIYELKGDYKTALEYHIEWAEANQIIEVERNERSLRESELQVNVLKKDQELAANQQRQIIYIVALVIGALLLALLYRNYRLKQRGNQKLKALNGELADKHVLLDKRNAENELLLKEIHHRVKNNLELVKSLLALQSAQMEDSTTKDAMIASQNRVQSMGIIHQKLYQGENLGSIEMKDYFLNLGEGILDTFDAEDKVKIECAMENLELDVDTAVPIGLIVNELVTNALKYAFPNDGKGNILISLSQSTPETLTLKVADNGVGKVIGLPPKGTGFGTQLIQLLTQQLDGKMLEEHDNGTSVSFQFKTKPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCS3</accession>
    <name>A0A5C6ZCS3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lipocalin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000027">
        <property type="protein sequence ID" value="TXD87267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023068695" evidence="1">
        <location>
            <begin position="21"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="132" mass="14164" checksum="99242AEC979C3616" modified="2019-11-13" version="1">MKRLLVGVMSLLLINSCANDDDASQNDLTLVGQWQLVAFYGDPGDGSGDFQPLTSSKTITFEADGSLSSNANLCLVFSDVGEPSAGTYSETDASISIADCSDFNLVFEISATNLIIDYPCIEACREKYVKLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD04</accession>
    <name>A0A5C6ZD04_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycoside hydrolase family 16 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_16050</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000021">
        <property type="protein sequence ID" value="TXD87686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002126">
        <property type="entry name" value="Cadherin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="GH16"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50268">
        <property type="entry name" value="CADHERIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cadherin" evidence="2">
        <location>
            <begin position="23"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="GH16" evidence="3">
        <location>
            <begin position="329"/>
            <end position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD87686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="562" mass="60599" checksum="D2FF2C783E59A138" modified="2019-11-13" version="1">MGNFRNYVGILAVLLLCAGCQDDDSTFGAIVAPSNIVITTEIVGVDADNPNGDGSGQVIFKATADQALGYSFAYGDGTDGVVPSGETVHRYSVVGLNTYTVVVNALGAGGLSSSATLDVEVFSSFDDLEAKQLLSGGEVSSKTWYPKLDENGHLGVGPTLAQDIGDDGTLNGHWFPQYDSTDAFGKCAAADSDCFCDLSLTFELDATGNLTFNQNNNGSTFFNWAHGAVVGQQLDEFADACFEFDTMAESAVTLVPSSTDWSQVADPEFPVPRGTVMNFTNDGFMGYYTGVSSYEILQIDSNYLYVRFFDNVNPDLAWYQMFTTTPATSDFTSTFNDLVWSDEFDTDGAPDPANWTYDIGTGSNGWGNGEAQVYTNDAENVTIENGILRIIAKANGDGYTSARLKTQNLYEFTYGRVEIRAKLPAAQGTWPALWSLGADIEVNPWPGCGEIDIIEQTGQDKNTVLATIHHPAVSPGAGDTGTKALPTATTTFHNYSLDWTAETITFLIDDEVFRSIPNTPDLPFKSDFFLIMNVAMGGSLGGVIDPAFTEDQMEVDYVRVYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD07</accession>
    <name>A0A5C6ZD07_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19880</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000051">
        <property type="protein sequence ID" value="TXD86568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="68" mass="7622" checksum="14AE25FAC60AD588" modified="2019-11-13" version="1">MEIELKSEITCPNCGHKKVEEMPTNACQFFYECVNCKTVLKPNEGDCCVYCSFGTMACPPIQENKSCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD41</accession>
    <name>A0A5C6ZD41_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">VWA domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_18120</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000030">
        <property type="protein sequence ID" value="TXD87052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01467">
        <property type="entry name" value="vWA_BatA_type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024163">
        <property type="entry name" value="Aerotolerance_reg_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033881">
        <property type="entry name" value="vWA_BatA_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07584">
        <property type="entry name" value="BatA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="311"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="93"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="334" mass="37522" checksum="B0DC0E0E446F4F0E" modified="2019-11-13" version="1">MLEGVEFVNKGFFWLLLLLPIAMLWYALKRKRQTAELKVSSIKGFKVGSSVLPKLRPILFILRLLALAFIIVALARPRTSDESTKIKTTKGIDIVMAIDVSASMLAKDLLPNRLEALKNVASEFIKGRPNDRIGLVEYAGESYTKTPITSDKAIVLRSLRDIKYNEIIEGGTAIGMGLATSVNRLKDSKAKSKVIILLTDGVNNSGFIDPKIASELALEYGIKVYTIGLGTNGMALSPYSILPNGNFQYRRMQVEIDEDLLKSIADMTEGKYFRATDNEKLKEIYSEINKLEKTEVDELKFTTYDEKFRPLVLIALGLLMLEFLMRFTLFRSFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDA7</accession>
    <name>A0A5C6ZDA7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_16055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000021">
        <property type="protein sequence ID" value="TXD87668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022409">
        <property type="entry name" value="PKD/Chitinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035986">
        <property type="entry name" value="PKD_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00089">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49299">
        <property type="entry name" value="SSF49299"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKD" evidence="1">
        <location>
            <begin position="40"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="PKD" evidence="1">
        <location>
            <begin position="123"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="694" mass="73749" checksum="2654A19179DD192F" modified="2019-11-13" version="1">MKIFKYTLGLCLVMTAFFGCEKDDDNTDFVNGINAPSNVSALVTVTQDNSGLVKITPLAEGVTTFTIDYGDNSEAASNIQPGAFVEHTYAEGTYQASIQAFGLNGRSTSVTQEIMVSFNAPENLVVTITNDAAVSRKVNVTAVADFALSYEVDFGQAGSEPVMINDGDTASFIYDEAGTYTITVTAFSAAIETVQYTEDFLVTEILQPLTGAPTPPSRQDSDVISMFSNAYEQDVNVSSWRSDWSTSTLTDLQIAGNDTKFYADADFVGVEFYGDAAVDASQMDSFHMDFWSVNATTFRVKLVDLGGEATEAEIVFTDLPQNEWVSIEIPMSDFTDAGMTSINSIQQMIFSGLPTGTFDFFIDNVYFYRAATAAGEGLEGTWKMAPEAGALGVGPSIGDVSFFSCDAVCVDSRACYYDDNYIFGADGTFTNDLGAESWIEGWQGGGDSCGTPVAPHDGSNPASYTYDEAAGTVTVNGVGAYIGLAKANNQGELPNVAVPSSITYNVSFIDANTINVNVDIGGGVYWQYRLIREGATNPLAGTWQMAPEAGALGIGPAIGDVSFFSCDAVCVDSRACYYDDNYIFGADGTFTNDLGAESWIEAWQGGGDSCGTPVAPHDGSNPATYTYNGSAGTITLNGTGAYIGLAKANNQGELPNVAVPSSITYNVSFVDANTINLNVDIGGGVYWQYKLVRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDE3</accession>
    <name>A0A5C6ZDE3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15610</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="117" mass="13071" checksum="C5D4221E8E81B807" modified="2019-11-13" version="1">MEKTETNTNTNTTTSEGKTIAIIAYLTIIGLIIAYVMNNEKKNAFAKYHIIQSLGIALTAIALSIVGLIPILGWIINLIGILVLLYMWIMGLINAINEKQQPVPILGKHYEEWFKNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDJ6</accession>
    <name>A0A5C6ZDJ6_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Diaminopimelate decarboxylase</fullName>
            <shortName evidence="2">DAP decarboxylase</shortName>
            <shortName evidence="2">DAPDC</shortName>
            <ecNumber evidence="2 3">4.1.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2 6" type="primary">lysA</name>
        <name evidence="6" type="ORF">ESY86_17680</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 3">
            <text>H(+) + meso-2,6-diaminoheptanedioate = CO2 + L-lysine</text>
            <dbReference type="Rhea" id="RHEA:15101"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
            <dbReference type="EC" id="4.1.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 2 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 3">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; L-lysine from DL-2,6-diaminopimelate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.20" evidence="2 3"/>
    <dbReference type="EMBL" id="VORO01000027">
        <property type="protein sequence ID" value="TXD87265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00027"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008836">
        <property type="term" value="F:diaminopimelate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06828">
        <property type="entry name" value="PLPDE_III_DapDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02120">
        <property type="entry name" value="LysA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002986">
        <property type="entry name" value="DAP_deCOOHase_LysA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022643">
        <property type="entry name" value="De-COase2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022644">
        <property type="entry name" value="De-COase2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000183">
        <property type="entry name" value="Orn/DAP/Arg_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02784">
        <property type="entry name" value="Orn_Arg_deC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00278">
        <property type="entry name" value="Orn_DAP_Arg_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01181">
        <property type="entry name" value="DAPDCRBXLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01179">
        <property type="entry name" value="ODADCRBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50621">
        <property type="entry name" value="SSF50621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01048">
        <property type="entry name" value="lysA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 3" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="2 3 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 3" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orn_DAP_Arg_deC" evidence="4">
        <location>
            <begin position="18"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="Orn_Arg_deC_N" evidence="5">
        <location>
            <begin position="24"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="298"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="302"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="329"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="356"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD87265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="401" mass="45386" checksum="15B9384037111B3E" modified="2019-11-13" version="1">MEGNTLLQIAKDFGSPVYVYDAEKIQFQYKRLTSAFNKVKHLKLNYAVKALSNISILKLFNQMGSGLDTVSIQEVQLGLKAGFKPEQIIYTPNGVSLDEIEKAAKLGVQVNIDNLSILEQFGTKHPKTPVCIRINPHVMAGGNTNISVGHIDSKFGISIHQIPLLLRIVENTKMNINGIHMHTGSDILDIDVFLYASEILFDTAKHFTQLEFIDFGSGFKVPYKPGDIETNIEELGEKLSKRFNDFCKEYGRELTLAFEPGKFLVSEAGYFLTKVNVVKQTTSTVFAQVDSGFNHLIRPMLYGSQHEISNISNPEGRERFYSVVGYICETDTFANNRRISEIKEDDILAFKNAGAYCFSMASNYNSRYRPAEVLWYKQKAHLIRKRETFEDILNHQIAIEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDL0</accession>
    <name>A0A5C6ZDL0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_16440</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87616.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="39"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87616.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="96" mass="10956" checksum="2F5F2C7DF5D79BF5" modified="2019-11-13" version="1">MKNVTDFEDILIGTYGKKGTEKRNKYDADSLAFRLGIMLKEARKEANLTQEELAERTGTKKSYISRIERGLSDIQISTYYKLIELGLGKHLNIEIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDS6</accession>
    <name>A0A5C6ZDS6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TetR/AcrR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_19155</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000037">
        <property type="protein sequence ID" value="TXD86812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="24"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="227" mass="26261" checksum="469C01D014CE3E49" modified="2019-11-13" version="1">MQELLKNLKIKVNNKTYLKDPETSELGKKILQRSIILISEIGFEAFTFRKLGAAISSNESSVYRYFENKHKLLLYLTSRYWAQIEYEIVVKTFSIPDPVEKLETIIAIVTEKIETDTDHSHIDEKLLNQIVISEYPKSFLTKEVDVENKEGYYTIYKRLISRIKDAIIAVDKDYPFPVTLASTLVEGSMHQHFLSDHFPTLTDCGTVTTPTKFYSHLIFNTLKKPSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDZ2</accession>
    <name>A0A5C6ZDZ2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_13980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047474">
        <property type="term" value="F:long-chain fatty acid luciferin component ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008218">
        <property type="term" value="P:bioluminescence"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007534">
        <property type="entry name" value="LuxE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04443">
        <property type="entry name" value="LuxE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="LuxE" evidence="1">
        <location>
            <begin position="16"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="LuxE" evidence="1">
        <location>
            <begin position="154"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="326" mass="36716" checksum="F87C7E83CD04ACE4" modified="2019-11-13" version="1">MIEPTRIFSIASEAEFTRTALDVFKFQFEHNKVYRSFCDLLCKHPSDVKTVADIPFLPIQFFKSHEIKSSTLPIQATFSSSGTTGSSTSKHGVTDLTVYEASFRKAFQQFYGNITDYVILALLPSYLERQGASLIYMVDDMIKHSQHPESGFYLDTINKLKSKLLALDREGKKVLLIGVSFALLDLVEQYQFSLKHTIVMETGGMKGRRKELVREELHQILKNGFGVDTIHSEYGMTELLSQAYSKGDGIFECPNWMRILTRDPEDALTLQQAGKTGGINVIDLANVNSCAFIATQDLGRVHEDHSFEIIGRFDTSDIRGCNLMVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE13</accession>
    <name>A0A5C6ZE13_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_15755</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026487">
        <property type="entry name" value="CHP04141"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19614">
        <property type="entry name" value="DUF6119"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04141">
        <property type="entry name" value="TIGR04141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="428" mass="49457" checksum="568A7ECD462390FA" modified="2019-11-13" version="1">MERDFGLRTALNLVDSEKFISVDKANLSDMGLLTKMQSSRKSKPEAFNLDVVSDLLKGVTGGLAKGSNDLGTMITGNEGVYLSPKVNFKDIPEKLRKLLKAYKSNKYKTNFDWIDNLKEEKNPSTVEELRALLIAALKKQDTTNIHLASPNIIDWESYEGYAYSEVADDLKMDLDISDFYAYKNDKLEDLDWNTLKRLSIYLKYANNEFRISAPLWRFINFEVNRKGSTYVFTLGKWYHINKNYIESIREYVKNVEESNLVFLKCPKNFSEGDYNESLAKSKKDYLLFDKNLVKSDYFNRSHIEVCDVLSILNKEFIHVKPRSSSSTLSHLFAQGRVSSIAILRDNSFRKNLRAKLKALGAEMDFIPLDRKKLKPSDYTITFALIDKRDRSFIDALPFFSLINFRLTLENLQEQGFKVKIKNILRESS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE32</accession>
    <name>A0A5C6ZE32_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF2807 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_17200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000025">
        <property type="protein sequence ID" value="TXD87405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021255">
        <property type="entry name" value="DUF2807"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10988">
        <property type="entry name" value="DUF2807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022891211" evidence="2">
        <location>
            <begin position="18"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2807" evidence="3">
        <location>
            <begin position="41"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="221"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD87405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="240" mass="25170" checksum="28E5EFBC13E2CCEE" modified="2019-11-13" version="1">MKSLILALASLATFSCAQGKWGNNAIKGNGNLKTITRTTSDYDAIHCAGSFDYILVEGTEGDIKIEGEENLLEYIITEVQNGTLSITTENNVNLNTSTNKGIKITIPFKEITEVSLSGSGDLWNTDVIDTNNLSASISGSGDVVLEIKTTSAKARISGSGDLTFTGTTEKLEANVTGSGNFHGFDIRSQDVNVSVTGSGDAAVFSTNKLIARVTGSGDIEFRGNPKTEDTKVTGSGSIGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE86</accession>
    <name>A0A5C6ZE86_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">SRPBCC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_13580</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="105" mass="12502" checksum="BA41495BAEBF2FF9" modified="2019-11-13" version="1">MHESVTWRAKHFGIYQNLTSKITEFDRPNYFTDEMQSGIFKAFKHEHHFAELNGGTLMTDIFDYKSPFGILGKLADKLFLEKYMTEFLTKRNRIVKEFAETDKWP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEA1</accession>
    <name>A0A5C6ZEA1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">UDP-N-acetylglucosamine 2-epimerase (Hydrolyzing)</fullName>
            <ecNumber evidence="2">3.2.1.183</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">neuC</name>
        <name evidence="2" type="ORF">ESY86_16845</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.183" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000024">
        <property type="protein sequence ID" value="TXD87446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008761">
        <property type="term" value="F:UDP-N-acetylglucosamine 2-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006047">
        <property type="term" value="P:UDP-N-acetylglucosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020004">
        <property type="entry name" value="UDP-GlcNAc_Epase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003331">
        <property type="entry name" value="UDP_GlcNAc_Epimerase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029767">
        <property type="entry name" value="WecB-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43174">
        <property type="entry name" value="PTHR43174"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02350">
        <property type="entry name" value="Epimerase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03568">
        <property type="entry name" value="NeuC_NnaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase_2" evidence="1">
        <location>
            <begin position="24"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="384" mass="42246" checksum="26880C4C4ADBB894" modified="2019-11-13" version="1">MIKRKICVVITARPSYSRVKTLLQAIQTHPDLELQLIVAASALLDRYGSAVNYIKNDGFDIAAKVFNVLEGENLTAAAKTTGIGILELSTVFDNLKPDIVITVADRFETMATAISASYMNIPLAHLQGGEVTGNIDEKVRHAITKLADYHFVASEGAKERVIKLGENPEMVFNTGCPSIDLAYLVKDCTMDFDPYQKYGGVGAKPDLSNGYLVVMQHPVTTEYSDSRKHIEQTLKAIAELEIPTLWFWPNVDAGADGTSTGIRAYREQHKIEHIHFFKNMEGTDFLKLLNNAKALIGNSSVGIRECAYLGVPVVNIGSRQHRRDRGHNSIDVGYHQNEIKQAIQSHLTNGKSAASSIYGGGNAGEQIADLLQKLTLQFHKTISY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEE2</accession>
    <name>A0A5C6ZEE2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type IX secretion system membrane protein PorP/SprF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18095</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000029">
        <property type="protein sequence ID" value="TXD87138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019861">
        <property type="entry name" value="PorP/SprF_Bacteroidetes"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11751">
        <property type="entry name" value="PorP_SprF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03519">
        <property type="entry name" value="T9SS_PorP_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="379"/>
            <end position="745"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1064" mass="114770" checksum="FA963466592A43E9" modified="2019-11-13" version="1">MKNGVLTIVFLFCAIQMFYSQEEDGVVSLALPTRNSLTFNRFLINPTFSFVREQHRYVSMTNKREWVQFDDAPTTYLASYSGRFRENMGIGIAVFQQNYGVLTTFGGTLNFAYNAQLQRDSNLTFGLNLGIYSSGIDAGRVVTNFEDPSLNTIPSNTLISVNPGINYGLAFLDFGVSIKNLALYNMSTSTLIEDNPEQSIQAHMMHTGYVRSNGFFDESKFSGLLRGELGKDNSIISAIAMLTVPKGIWAQVGYNTLYGVSGGLGLNITKSIAIEYNFEKALGDLTNFGPSHEVTLAYRFNTDRRYDYSGNDEVGSLISSEKRVKRPVSKIDKAQAEANRQQAIADRAQAKLDQEAKLKADEAANAKAKETAAAEAILVTEAKAEAEAKAEQVAELKSAAEVEAQASAEAQLAAAEAARLKAEAEAEAETQRVAQAEAAARQEAAAQAVLAAAETARLKAEAEAKAETQRIAQTEAIARQEAAARVKLAAAETARLKAEAEAEAETQRVAQAEAAARQEAAAQAELAAAETARLKAEAEAEAKAETQRVAQAEAAARQEAAAQAELAATETARLKAEAEAKAETQRVAQAEAAARQEAAAQAELAATEAARLKAEAEAKAETQRVAQAEAAARQEAAAQAVLAAAETARLKAEAEAEAETQRIAQAEAAQEAAAQAELAAAETARLKAEAEAEAEAETQRVAQAEAAARQEAADQAVLAAAETARLKAEAEAKAETQRVAQAEAAARQEAAAQAVLAIAEQQKTDSENNSLPNASDEMAKTMNALAESTASSGQSQQALIAELAAAVASKDKDLQDLKKENDLSEQGIFLAPKPFKSITAENNAIEALKVNLDNSIQARSNEIDELQTLYDQRVKIATMRNDEVTLFYKKNLDRLKAEQLTALSTRERLTASLKSIKIATEFERKRRIKRAAFDNEQDRFIQDKATLDRIKQNTNLSAVPLTAADFDFGEAQSANIQILKNVKNVENGFYVILAVHTDVSKRDAFLKNTVASGNTDVNFFYDVNTSKYYIYNEKINNVELANDALKSKGSEPYKGRLSIVKIEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEH6</accession>
    <name>A0A5C6ZEH6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF1761 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12655</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013879">
        <property type="entry name" value="DUF1761"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08570">
        <property type="entry name" value="DUF1761"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="160" mass="17954" checksum="CE39BFF552FF864E" modified="2019-11-13" version="1">MEFNYLAILAASAVPIVISLLWYHPKTLGILWMRESGMTEEKFRSSNVAVIYGVSLLLAIVLAFSVQLLVIHQMGVYSLMGGNPEAALPSYQAFMDDYGTAFRTFKHGALHGFLSALFLFFPVIAINALFERRSWKYIFINTGFWTLSLTIMGAIICGWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEI0</accession>
    <name>A0A5C6ZEI0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000029">
        <property type="protein sequence ID" value="TXD87135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023109012" evidence="1">
        <location>
            <begin position="22"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="150" mass="17248" checksum="DE9F8E7C3D41EC6A" modified="2019-11-13" version="1">MKTKLILCSLVLLMMTSFSFAQNKDDALNIISGNVSISKYHDRNDLDRMNKGELLKLYMERIEVIVKILPNIAFATKPGVTMTSLGIPDTKDHRNALEDNIKASNDYFDSTIEYQKKILPYSDKSNLIAAILFYEQTLKSLHTYNEFNRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEK4</accession>
    <name>A0A5C6ZEK4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RagB/SusD family nutrient uptake outer membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_12815</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SusD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033985">
        <property type="entry name" value="SusD-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012944">
        <property type="entry name" value="SusD_RagB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14322">
        <property type="entry name" value="SusD-like_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07980">
        <property type="entry name" value="SusD_RagB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="SusD-like_3" evidence="6">
        <location>
            <begin position="20"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="SusD_RagB" evidence="5">
        <location>
            <begin position="262"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD88395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="490" mass="54721" checksum="D4750234DB98AB90" modified="2019-11-13" version="1">MKNLIYLIVVAILCIGCSDDFLDKQPLDTINTENYPQTAEELVTVVNGAYQPLQRPKLYNLRMWTSDIMAGNSIVGAGGGTDGIETQDMSNFITQPDNAGVLDLWRGPWPGILMSNIVLETAPTLDIDEAIKNRSMGEAYFLRAHYYFILARYFGDVPIVTVPLNADDDLFPPRDPVNAVYDLIISDLNKAIQFLPPKSSFGQSDLGRASKGAALGMLAKVHLTLGNYDEVITLTTQVEGQGYALNINYYDNFNINDENSQESMFEVQYASDGGFGFFSDENQASWTSPFMGPRSSNFVGGAFGWNQPTQEFMNQYEAGDLRKDISVLYPGGPDFDGNAYQSSYSTTGYNVRKFLVPLSVIPGYDNSPMNFPVLRYADVLLMKAEALNELGQTNEAQNYLNMIRNRAGLDDIETGLSQVQFREAVLKERRLELAFEGQRWFDLIRVNNGQYGLDFLQSIGKDNAAQKHLLFPVPQIEIDRNPNLTQNLGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEQ1</accession>
    <name>A0A5C6ZEQ1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RagB/SusD family nutrient uptake outer membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_16060</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SusD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000021">
        <property type="protein sequence ID" value="TXD87669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033985">
        <property type="entry name" value="SusD-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012944">
        <property type="entry name" value="SusD_RagB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14322">
        <property type="entry name" value="SusD-like_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07980">
        <property type="entry name" value="SusD_RagB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="SusD-like_3" evidence="6">
        <location>
            <begin position="25"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="SusD_RagB" evidence="5">
        <location>
            <begin position="335"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD87669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="486" mass="54340" checksum="B9B8EFC7F0197213" modified="2019-11-13" version="1">MKNKLTYSFIVVFTIFGLSGCTDDFVERTPVYSIDSENYFNSESDYYNALIGAYDLLQSTYLNTILGEIASDNTLAGGESATDVIGWQQVDDMIHTPVNSEIKRIWDFMYAGVNRANYILEFQDKTDFEGKAIIIAEARFLRAYYYFELVKWFGPVPLKETRFTLGDETSIPRSPVEDVYALIEADLTFASNTLSYTAPQIGRATKGSAQALLGKAFLYQDKFTEAANVFETLINNGPYDLVSDYNTLFESQGENGIESVFEVQYTDVEGASFLCLQCSEGNVAVGFSGVRNYSGPIFTSGFSFNVPTQEVVDAFEAGDIRKDVAILDIEAWAAETGATFGTGYEHTGYFNRKYLPRKRSADAAGDLNLTNPNNYRAIRFADVLLMAAEAYARGGLNEDKARLYLNRVRTRANLSDVTASGNALIDAIYAERRTELVGEGHRFFDLVRTNRGSEIDGFSANRHELFPIPFEEIQFSNGNWQQNQGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF25</accession>
    <name>A0A5C6ZF25_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 5'(3')-deoxyribonucleotidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008253">
        <property type="term" value="F:5'-nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009264">
        <property type="term" value="P:deoxyribonucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010708">
        <property type="entry name" value="5'(3')-deoxyribonucleotidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06941">
        <property type="entry name" value="NT5C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="143" mass="16314" checksum="632EB82418E87C40" modified="2019-11-13" version="1">MDGVLVNFQSGIDRISEEESVKYAGNLDEVPGIFSLMEPNEGAIEGYKWLCKNFDTYILSTAPWENPSAWQDKLHWVKKYLPELAYKRLTLSHNKNLLNGDFLIDDRTANGAGKFVGKHIHFKEEGKGFEDWKAVVAYMKNLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF88</accession>
    <name>A0A5C6ZF88_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">CTP synthase</fullName>
            <ecNumber evidence="9">6.3.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Cytidine 5'-triphosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Cytidine triphosphate synthetase</fullName>
            <shortName evidence="9">CTP synthetase</shortName>
            <shortName evidence="9">CTPS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">UTP--ammonia ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">pyrG</name>
        <name evidence="12" type="ORF">ESY86_12225</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + H2O + L-glutamine + UTP = ADP + CTP + 2 H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:26426"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + NH4(+) + UTP = ADP + CTP + 2 H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:16597"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>H2O + L-glutamine = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="9">Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Pyrimidine metabolism; CTP biosynthesis via de novo pathway; CTP from UDP: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="9">CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the CTP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.2" evidence="9"/>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00159">
        <property type="reaction ID" value="UER00277"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003883">
        <property type="term" value="F:CTP synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044210">
        <property type="term" value="P:'de novo' CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03113">
        <property type="entry name" value="CTPS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01746">
        <property type="entry name" value="GATase1_CTP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01227">
        <property type="entry name" value="PyrG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004468">
        <property type="entry name" value="CTP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017456">
        <property type="entry name" value="CTP_synthase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033828">
        <property type="entry name" value="GATase1_CTP_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11550">
        <property type="entry name" value="PTHR11550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06418">
        <property type="entry name" value="CTP_synth_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00337">
        <property type="entry name" value="PyrG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="4 9 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 9" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CTP_synth_N" evidence="11">
        <location>
            <begin position="5"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="GATase" evidence="10">
        <location>
            <begin position="304"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Amidoligase domain" evidence="9">
        <location>
            <begin position="1"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="region of interest" description="L-glutamine binding" evidence="9">
        <location>
            <begin position="384"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; for glutamine hydrolysis" evidence="9">
        <location>
            <position position="383"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="509"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="511"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="15"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="16"/>
            <end position="21"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="150"/>
            <end position="152"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <note>allosteric inhibitor</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="190"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="226"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="356"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="407"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="464"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF06418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TXD88505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="545" mass="60732" checksum="8EB527B547D304B0" modified="2019-11-13" version="1">MTTTKYIFVTGGVSSSLGKGIIAASLAKLLQAQGYRTTIQKLDPYINVDPGTLNPYEHGECYVTDDGAETDLDLGHYERFLNVATSQSNNVTTGRIYQSVIEKERRGEFLGKTVQVIPHITDEIKQRIQILGNSGDYDIVITEIGGTVGDIESLPYIEAVRQLKWDLGEHNAIVIHLTLVPYLSAAGELKTKPTQHSVKTLMESGVMADILVCRTEHELPSDLRDKLAKFCNVRREAVIQSIDASTIYDVPNLMLEQGLDTVVLKKLELDSSEPDLTRWNQFLQRHKNPKGEVVIGLIGKYVELQDSYKSILESFIHAGAENEVKVKVQSIHSEYISEKNVAKKFAHLDAVLVAPGFGERGIEGKIAAVKYVRENNIPFLGICLGMQMAVIEFSRNVLGIADANSSEMDENTNNPVIDLMASQKMVTDKGGTMRLGAWECELVEGSIAYKVYQNKTIKERHRHRYEFNNKYKAQIEEAGMKATGINPETGLVEIIEIPANNWFVGVQYHPEYKSTVANPHPLFVAFVKAALDYKNRVIDANMAQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFD2</accession>
    <name>A0A5C6ZFD2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ubiquinone biosynthesis protein UbiA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_14740</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0830">Ubiquinone</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="103"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="143"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="172"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="218"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="244"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="276"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD87924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="300" mass="35073" checksum="6F049358A0CAAFA5" modified="2019-11-13" version="1">MLSRKQKHILLKFFSMFSVVRGYNILIVVIAQYLTSIYILAHDKPLKAVLFDLNLLMLVLASSAVIAGGYIINNFYDSEKDQINRPHKSRLDRLISQNTKLSFYFVLNFSAAIMASYVSFRAVVFFSIYIFGIWFYSHKLKKLPFIGNLTSAILMITPFFVVFLYYKNFEQVIFVHAFFLFLIISMRELTKDLENIKGDLLLNYKTIPVVYGEKASKIMLTVLTLLTLIPTQLLLFKYQIGHMYLFFYMSIFLLFIFMLLLWYSKTKTHYLILHNILKFIIVVGVFSIVLIEVSVVLNRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFI2</accession>
    <name>A0A5C6ZFI2_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">30S ribosomal protein S4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 10" type="primary">rpsD</name>
        <name evidence="10" type="ORF">ESY86_14955</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.</text>
    </comment>
    <comment type="function">
        <text evidence="6">With S5 and S12 plays an important role in translational accuracy.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the universal ribosomal protein uS4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01306_B">
        <property type="entry name" value="Ribosomal_S4_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022801">
        <property type="entry name" value="Ribosomal_S4/S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001912">
        <property type="entry name" value="Ribosomal_S4/S9_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005709">
        <property type="entry name" value="Ribosomal_S4_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831">
        <property type="entry name" value="PTHR11831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831:SF4">
        <property type="entry name" value="PTHR11831:SF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00163">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01390">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01017">
        <property type="entry name" value="rpsD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_S4" evidence="9">
        <location>
            <begin position="3"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="S4" evidence="8">
        <location>
            <begin position="93"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD87966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="201" mass="22789" checksum="5C6213FD5074826C" modified="2019-11-13" version="1">MARYTGPKTKIARKFGEAIFGDDKAFEKRNYPPGQHGNNRRRGKKSEYAIQLMEKQKAKYTYGILEKQFRNMFKKATSAPGITGEVLLQLCESRLDNVAYRMGLSPSRSGARQLVSHRHITVNGEIVNIPSYQLQAGDVVAVREKSKSLEAIQSSLANSSSVYEWITWNNDTKQGTYVSIPERVQIPENINEQNIVELYSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFM6</accession>
    <name>A0A5C6ZFM6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">S9 family peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_11905</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023302">
        <property type="entry name" value="Pept_S9A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002470">
        <property type="entry name" value="Peptidase_S9A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02897">
        <property type="entry name" value="Peptidase_S9_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00862">
        <property type="entry name" value="PROLIGOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S9_N" evidence="2">
        <location>
            <begin position="7"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9" evidence="1">
        <location>
            <begin position="469"/>
            <end position="680"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="686" mass="79377" checksum="D4D1DEFFA09F0ABA" modified="2019-11-13" version="1">MKTILNPPIARKIPKELSIHNDSRIDNYYWLNQREDQEVLDYLHAENEYYEQETAHTRDFEVNLFDEMKARIKEDDSSVPYKYNGYWYIVRYEKGKDYPIYSRKKETLEAAEEILFDCNAMAKDQSYFRLVGLSISPDNSMVAFGIDTTGRRQYKLQIKSLITDEIFSDAIENTTGSSTWASDNSTLFYTIKDEQTLRSNQIFKHKIGHAEAEDTLVFTEEDHTFGVAVYKSKSRKYIIIACYSTMTNEFHFILADEPDAKFKLFQERVRGLEYSISHYEDSFYILTNLDDAINFKLMKTPENKTSIKNWTEVLAHRAHVLLEDIDIFKDYLVISERSNGLNHIRIKRWDLKADYYLPFDSETYTAGTGSNVEFDTQILRYSYNSMTQPAAVIDFNMETKLKDIKKEQEVLDPHFDKDNYVSERLWATANDGSKIPMSLVRRKDTKINGEAPLLQYAYGSYGSTMDAYFSTIRLSLLNRGFIFVIAHVRGGEYLGRSWYEDGKLLTKKNTFSDFIDCSRFLIENKYTSAAHLYAMGGSAGGLLMGVIVNDAPELYHGVVAQVPFVDVVTTMLDETIPLTTGEYDEWGNPNDKLYYDYIKAYSPYDQVKKQAYPNMLITTGLHDSQVQYWEPAKWVAKLRTYKQDTNRLYLLTNMEAGHGGASGRFEALKEVAKEYAFLLDMEGITV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFX0</accession>
    <name>A0A5C6ZFX0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="153" mass="17493" checksum="9004933365478A32" modified="2019-11-13" version="1">MMRTQYSIIVMMMFSIFLFNCKTENKKRAPIDSAAQELSMADNLELKLNNGEKWVANTETHEGLKSMDSIMQAFVNSNATDYLELGKQLSKQTSYIIEKCSMKGESHDQLHVVLVPMLDEISILKESNNAEASNVAVSRLEQLIQQYFKHFSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFX6</accession>
    <name>A0A5C6ZFX6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF2490 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_13845</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019619">
        <property type="entry name" value="DUF2490"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10677">
        <property type="entry name" value="DUF2490"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="200" mass="23792" checksum="DB699526BA0DFBEB" modified="2019-11-13" version="1">MFTENIFSINHDFSDTYSTNFELGTRAFLYTNQETLFKTRQLELSHFSTLRLNLKSSISLGLKLRNRDWFEDSSSEIRLTQQFNTKTLLSTLRFGHRFRSEQRFYEDETVFRYRYRLALDVPLQGLKLDVGETYFVLYNEALWSISKISKPEFEYRISPSIGILLSKDLNLELGLEYRLDKLNMNTDHELFFNTSLDLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFY3</accession>
    <name>A0A5C6ZFY3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="376" mass="41052" checksum="3525DC7D0AA05CF2" modified="2019-11-13" version="1">MEKSRETIKTYFEIGDKPTEEQYQDTWDSFVHKDDQIPAEKIDGQDLQKTTDAGNSTTNDIQMVGGNLTITDGDTPENPFEGNLNINYTDEKSGNSFSIYNAIIKTKSAISQFFYGFSNLITHDAPEDISQVRGIYNRVRTMNSGTPGELMGTYNDVSYRNTGSGSINLLSGSENYVRVEDFGGTGTIANTIGFRSQIIHDNANVVSSRMWGGIFSLTHKTGNISNWTGVLIDLNQSSGTTVEAGEYLRLDSGIKLPNLNMKAINSVVNLPSYFKGLLESDITVEQIDTADGKVLPTKEWVQTNSASKFSSPIGDGALTTINVLHNLGSEDVIIRVRDSNTKTVVECTKTIVDSNTISLTFDAAPSADAYRVVVIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG43</accession>
    <name>A0A5C6ZG43_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_09795</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="249" mass="27714" checksum="C5C7D2683F852802" modified="2019-11-13" version="1">MTIILSYIKYWVNSFIRNLYWLYRLMNVKFDRNSNLSFPIIVEGRGKIAFGEYAQVQKGVNLGVGDNGSLVIGNECKLEKDALIRVGADKNFKIGHKFHLGHGVRLYVQDDWEFHNHTSIHSLCSISSREPGLAGKFIMHDNSHIGDNCIIDVSDDITIMENVAIGPNCTFYSHDHKYEDFSKAAWAGKTYTAKIFIGKNSWIGSNVTILPGVTIGSHVVVAAGSVVTKDLEDNSVYAGVPAKKMKTIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG55</accession>
    <name>A0A5C6ZG55_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">Alanine dehydrogenase</fullName>
            <ecNumber evidence="2 5">1.4.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">ald</name>
        <name evidence="11" type="ORF">ESY86_13905</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>H2O + L-alanine + NAD(+) = H(+) + NADH + NH4(+) + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:18405"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="EC" id="1.4.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the AlaDH/PNT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.1.1" evidence="2 5"/>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000286">
        <property type="term" value="F:alanine dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042853">
        <property type="term" value="P:L-alanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05305">
        <property type="entry name" value="L-AlaDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008141">
        <property type="entry name" value="Ala_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008143">
        <property type="entry name" value="Ala_DH/PNT_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007886">
        <property type="entry name" value="AlaDH/PNT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007698">
        <property type="entry name" value="AlaDH/PNT_NAD(H)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42795">
        <property type="entry name" value="PTHR42795"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01262">
        <property type="entry name" value="AlaDh_PNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05222">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000183">
        <property type="entry name" value="Alanine_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01002">
        <property type="entry name" value="AlaDh_PNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01003">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00518">
        <property type="entry name" value="alaDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00837">
        <property type="entry name" value="ALADH_PNT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 8" id="KW-0520">NAD</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 5 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AlaDh_PNT_N" evidence="10">
        <location>
            <begin position="4"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="AlaDh_PNT_C" evidence="9">
        <location>
            <begin position="149"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="6">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="6">
        <location>
            <position position="270"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="239"/>
            <end position="240"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="267"/>
            <end position="270"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="298"/>
            <end position="301"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR000183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000183-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000183-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000183-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD88189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="360" mass="38700" checksum="E7E97AEF04AF7B7D" modified="2019-11-13" version="1">MIIGIPKEIKNNESRVGMTPGGVFELTKKKHSVFIQSTAGEGSGFPDKLYTEVGAVIVDSIEEVYAKSDMIVKVKEPIAYEYPLIKSNQLLFTYFHFASSQTLTEAMIKSNSVCIAYETVEDEDGTLPLLTPMSEVAGRMAIQQGAKYLEKPIKGRGVLLGGVPGVPPGKVLILGAGVVGVQAAKMAAGLGAHVTIMDINMKRLRYVNDVMPSHVTTEFSSEYNIRKHIQTHDLVVGGVLVKGGKAPKLITRDMLKLMRPGTVVVDVAVDQGGCFETTKATTHEDPIYIIDDVVHYCVANMPGAVPYTSTLALTNVTLPYVLKLANTGWEAACEADATLAKGLNIVHGEIVYDGIAEAFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG92</accession>
    <name>A0A5C6ZG92_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Response regulator transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_10045</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="174" mass="20141" checksum="6F5A99CAB2AF9F37" modified="2019-11-13" version="1">MKQLQRFKQDLVFLDLSLPVSKDKKFLSGDDIGLWLREKSPETKILIFTFISDSERIRSIIKTIKPDGFINKSDFEPSNLSNVVKTILAGGSHYSQIIKNHETDQIVDRYITDEMDRKIVYHLSMGEKTKDLPALVHLSLRSIEERKVKLRDLFGITKDSDSNLIKEAKKRHII</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGE4</accession>
    <name>A0A5C6ZGE4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Molybdenum cofactor biosynthesis protein MoaE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_13315</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00756">
        <property type="entry name" value="MoaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036563">
        <property type="entry name" value="MoaE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003448">
        <property type="entry name" value="Mopterin_biosynth_MoaE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02391">
        <property type="entry name" value="MoaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54690">
        <property type="entry name" value="SSF54690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="147" mass="16634" checksum="051F8C783B6A4482" modified="2019-11-13" version="1">MDKKKPKKVFVQGAIPPEKIANSIANHQSKTNIGAHSIFLGQIRADEIDGKMVSAIEYSAYEDMAERVFHEIREAAFSKFDITCAHIYHSLGQVKTGELCLFVFTSSAHRKIAIEACNYFVEEIKANVPIFGKEIFEDETHQWKVNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGM0</accession>
    <name>A0A5C6ZGM0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">OmpA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_12730</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006664">
        <property type="entry name" value="OMP_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01021">
        <property type="entry name" value="OMPADOMAIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023142631" evidence="3">
        <location>
            <begin position="20"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="OmpA-like" evidence="4">
        <location>
            <begin position="16"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="OmpA-like" evidence="4">
        <location>
            <begin position="162"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD88378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="287" mass="33010" checksum="EEBBFD107B4424DC" modified="2019-11-13" version="1">MKMKVLPILLILSSQVFFAQKDMTHEVYFETDKYEVLSTEHSRLLLFISEIEGMDIAKVSIYGFTDDRGSDTYNMNLSQERANAIKTIFSNNEFDESIITNVDGKGKILLKLIQEDDIHKIRSLNRKVEIVVSPVFPPKPKKTETELANDKQDLKKLLDEQLKAGDKFTLENILFKTGYSKLLAESKPTLEELAEVLLKRKDIYFTIQGHVCCTQNSRDAIDRQTKKRNLSVARAKFIYDYLAKKGIAKERMKYVGMRRKFPLGGDPKLDRRVEILVTYANDSLNKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGR5</accession>
    <name>A0A5C6ZGR5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Membrane protein insertase YidC</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 13">Foldase YidC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11 13">Membrane integrase YidC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Membrane protein YidC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13 16" type="primary">yidC</name>
        <name evidence="16" type="ORF">ESY86_12220</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Interacts with the Sec translocase complex via SecD. Specifically interacts with transmembrane segments of nascent integral membrane proteins during membrane integration.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cell membrane</location>
            <topology evidence="13">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the OXA1/ALB3/YidC family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032977">
        <property type="term" value="F:membrane insertase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01810">
        <property type="entry name" value="YidC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019998">
        <property type="entry name" value="Membr_insert_YidC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028055">
        <property type="entry name" value="Membr_insert_YidC/Oxa1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028053">
        <property type="entry name" value="Membr_insert_YidC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001708">
        <property type="entry name" value="YidC/ALB3/OXA1/COX18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038210">
        <property type="entry name" value="YidC_periplasmic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038221">
        <property type="entry name" value="YidC_periplasmic_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12428">
        <property type="entry name" value="PTHR12428"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02096">
        <property type="entry name" value="60KD_IMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14849">
        <property type="entry name" value="YidC_periplas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00701">
        <property type="entry name" value="60KDINNERMP"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03593">
        <property type="entry name" value="yidC_nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03592">
        <property type="entry name" value="yidC_oxa1_cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 13" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 13" id="KW-0143">Chaperone</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 13" id="KW-0653">Protein transport</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 13" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="383"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="456"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="505"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="544"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="569"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="domain" description="YidC_periplas" evidence="15">
        <location>
            <begin position="103"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="605"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="14">
        <location>
            <begin position="612"/>
            <end position="633"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00033245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF14849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="TXD88504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="633" mass="72954" checksum="6978605EB93C6611" modified="2019-11-13" version="1">MEEKKFDVKSIIGFVLIFGILLFMMWRNQPTPEELAEQKRLEQVEASRQADAAEKEDDTKVITEEDFSSGNAIDSLQLENLKNKLGAFAYSSTLASASQDETVVETDVLEVTFSNKGGFISEVKLKNFVDYDSVPIYLIKNGNQYFNINFGTSDNRILNTKDLFFEPSVTKNGDNTVVSMRLKSSEDQYLEYRYELQPDNYMMDFSIESNGLGNVINSSQDVNLDWRLKTFRHDQSITYENRYTRLTYMHEGDKISKLNQSGEEEEIIEDARWLSYRQHFFSSILVADQLIKKARISTEDLVEDEEVDSVFTKQFASKFPLTFNNGEASNDFQLYFGPTDSKILKQYDYELDESIPFGWGIFGWINKALFIPLFGFLSSFLPYGIAIIVMTILIKLVMSFVQYKQFLSQAKMKVLKPELDAIREKHKDNKMKAQQETMALQNKAGASPLAGCLPGLIQLPVFYALFMFFPTAFILRQKSFLWADDLSSYDVIAQLPIKIPFYGDHVSLFPILAAIAIFFYMKMTTGQQMAAQPTQEGMPDMSKIMKYMIYFSPILMLVFFNQYASGLSLYYFVSNMISIGIMLVIKNYILDEDKIHAQIQVNKKKPKKQNKFQKKMAEMMEQAEQQKQSQKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGR7</accession>
    <name>A0A5C6ZGR7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_15210</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071702">
        <property type="term" value="P:organic substance transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039426">
        <property type="entry name" value="BtuB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010917">
        <property type="entry name" value="TonB_rcpt_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30069">
        <property type="entry name" value="PTHR30069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01156">
        <property type="entry name" value="TONB_DEPENDENT_REC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0798">TonB box</keyword>
    <feature type="domain" description="Plug" evidence="7">
        <location>
            <begin position="112"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="6">
        <location>
            <begin position="326"/>
            <end position="800"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD87821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="804" mass="90704" checksum="A8E7B1D2886920D1" modified="2019-11-13" version="1">MKYITSVILFLVITTMYAQTITVLERDTQEPISGVLIYAAKKNKTVTSNLSGRANLEVFSASEALFFQALGYKILKLRKADITKANNLVYLQPKLEGLDQVLISASKFEQRKRDIPQTIVNINAGDIAFDNPQTSADLLESSGNVYIQKSQLGGGSPIIRGFSANRLLITVDGVRMNNAIFRGGNLQNVISVDPFTIQNTEITIGAGGVAYGSDAIGGVMSFYTKKPNFAQNDTLQFSANAVVRYATANQEKTGHLDLNFGLKKWAFLSSVSYTDFDDLRMGRHGPDDYLRPEYVVTENGEDVIVQNNEPRVQKPTGYDQINLLQKVRYQPENDLNFDLGLFYTSTSKYPRYDRLIRSRNNELLAAEWNYGPQGWFMANLQITKTNANRQFYDKVQTTVAYQNFQESRFDRDFQSAIRNSREEAVNAYSMNLDFEKQLTQQHYLFYGLEYVYNGIHSEGETENIETNVTLPAVSRYPDGSSWQSIAAYASYKFKPSENFVLQTGLRYNHILIDADFTENNLFLNLPFDKTEIDTGALTGTAGISWSPNDMLQWRLNGSTAFRAPNIDDVGKIFDSEPGSVVVPNQNLKPEYAYGGELGLRLNFNEFLRFDMATYYTYLDNALVRRDFSLNGETQIEYDAELSTVQAVQNASEAKIYGFEVGMEAHFTEDLRLTSQYNVIGGKEQDENGMEVPARHVVPYFGNVHLIWKHTDVKADAFLEFNNELSFSQLSPSETAKDYLYASNANGNPYAASWYTLNLRTQYQISNTARISATLENITDQRYQTYSSGIAAPGRNLILALLYSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGU2</accession>
    <name>A0A5C6ZGU2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="11">DEAD/DEAH box helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">ESY86_10310</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005580">
        <property type="entry name" value="DbpA/CsdA_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03880">
        <property type="entry name" value="DbpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Q_MOTIF" evidence="10">
        <location>
            <begin position="2"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="34"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="228"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="534"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="5">
        <location>
            <begin position="2"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="551"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="573"/>
            <end position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD89150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="615" mass="69103" checksum="744FE2D5A8063F58" modified="2019-11-13" version="1">MSTFKELGLREDLLNAVNDLGFETPSDVQAQAIPILLEKDTDLVALAQTGTGKTAAFGFPMLQKIDIDSRTTQGLILSPTRELCLQITNEIKLYGKYCKGLNVTAIYGGASISDQARQVKRGSQIIVATPGRMKDMINRNMVDISKIEYAVLDEADEMLNMGFYEDITDILSHTPKEKNTWLFSATMPKEVSRIAKDFMRDPIEITVGNKNESTNQVSHEYYLVTARDRYQALKRLCDANPDIFSVIFCRTKRDTQKVAENLIEDGYSAGALHGDLSQNQRDLVMKSFRNKQIQMLVATDVAARGIDVDDITHVINYQLPDEPEIYTHRSGRTGRAGKTGISMVIVSKSEVRKIKSIERIIKKQFEKKEIPSGIDICEVQLMSLANKIHTTKVNNEIDKYLDSINALFVDTDKDELIKKFFSVEFSRFFNYYQKTKDLNSIATSSRDSEGGRDYGGSGNESRFFINVGKKDGFDWMQLKDFLKEQLQLGRDDVFKVDVKDSFSFFNTEKANEEKILAFFTDFKYEGRFVNVEVSEDKGGRSGGGRRNSGGGGGKRRRDDSPRGERRSGGRRSDSGSGFGSGNRKDRRSASGSGAGSRRTETSSASDRPRRSRRRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGV1</accession>
    <name>A0A5C6ZGV1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ESY86_12175</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038731">
        <property type="entry name" value="RgtA/B/C-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13231">
        <property type="entry name" value="PMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="116"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="139"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="162"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="209"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="258"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="295"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="317"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="349"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="381"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="410"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="domain" description="PMT_2" evidence="9">
        <location>
            <begin position="63"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD88496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="542" mass="62178" checksum="01608D39A2E8B521" modified="2019-11-13" version="1">MLRKLYNKPILSLSILLLLMLGLHLDVLPVSIMEARNFITAREMITDGNWLLTTMNGEARYQKPPLPSWITAIFGLIFGIKNLVAFRFPAVLFVLITGVYVFLLSKRLTQNKSQSFNTALISISSLYVIVIAFEAPSDIFTHGFMLMGIYHLFVLFKDHTHYLKRSLLAGLFIGCSILSKGPVSFYVLLLPFLLAFGFSYRYRFSKKLLLSFLGSLLLAVIIGGSWYLYVRLEDPETLLAIAETETGNWTSYNVRPFYYYWSFFTQSGIWTIPAFVSLLYPYLKTRVSNLKAYKFSLYWTIFAVILLSVIPEKKSRYLMPVLIPLALNTGFYIEYLIRQFKTMRDKRETIPVYFHFGLIAVIALAIPVVVYLFLAEDLSGLWIWYVLLSVASVSIGFVLLLQLKQKQIKTVFYLSILFFVSLLVFGLPLSEAIKSDNYKSIANLAEDMEAKQIPVYGYNSSPELLWQYGAKLLPLKDDTGFVFPKNNTLALVATNLSETDRKSLEIVYTIEKIDRYDLNLPAPETRGYNNRLQAELFLLHRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGW1</accession>
    <name>A0A5C6ZGW1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_12235</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025698">
        <property type="entry name" value="2TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010559">
        <property type="entry name" value="Sig_transdc_His_kin_internal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13239">
        <property type="entry name" value="2TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06580">
        <property type="entry name" value="His_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="372"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="397"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="His_kinase" evidence="2">
        <location>
            <begin position="159"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="2TM" evidence="3">
        <location>
            <begin position="361"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="449" mass="52577" checksum="A3E3DF82F7EFBA6D" modified="2019-11-13" version="1">MVKAFKSIIITFIMGCIVYAIAKLISGGFAYKTINAFLIDFSFYQLYTFVLRYANSLFFNYMEQRQWRKQDTLKRIVLGILGSTIITLICLFFLRVGVEVYFFGMPFEKFIANESWQGYSFGLWITLSIVSVFHVIYFYNKYQKNKIKEQKVIAGTASAKFDALKNQLDPHFLFNSLNVLTSLIEENPDNAQKFTTSLSKVYRYVLEQKNKDLIPVDEELDFARTYMMLLKMRFEDSIIFEIPDRASNPESKVVPLSLQLLLENAVKHNMVTSTKPLHIKIYEQGGMLVVDNNLQTKQIVKKSSGVGLENIKQRYKLLTHKTLSIAENAGRFTVAIPMLTKQTSIMRTIEPITAYDDSYVRARKRVEELKEFYYSLLSYCVVIPFLIFIYYQYTPGIIQWFWFPMLGWGMGLAFHAYKVYVNDGMLGKNWEKRQIEKYLREEEEQQPWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGW7</accession>
    <name>A0A5C6ZGW7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methylmalonyl-CoA epimerase</fullName>
            <ecNumber evidence="3">5.1.99.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">mce</name>
        <name evidence="3" type="ORF">ESY86_12905</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methylmalonyl-CoA epimerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.99.1" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004493">
        <property type="term" value="F:methylmalonyl-CoA epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07249">
        <property type="entry name" value="MMCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017515">
        <property type="entry name" value="MeMalonyl-CoA_epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03081">
        <property type="entry name" value="metmalonyl_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="2">
        <location>
            <begin position="5"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="136" mass="14955" checksum="E3C87863F42883B3" modified="2019-11-13" version="1">MGLTKIEHIGIAVKDIEASNELFAALFGKKHYKTEAVESEQVTTSFFEAGPNKVELLQATSAESPIAKFIEKKGEGIHHIAFAVDDIEAEIKRLTAEGFKMIHEIPKKGADNKLIAFLHPKSSNGVLIELCQEIKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGZ4</accession>
    <name>A0A5C6ZGZ4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">ATP-dependent Clp protease proteolytic subunit</fullName>
            <ecNumber evidence="2">3.4.21.92</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Endopeptidase Clp</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 4" type="primary">clpP</name>
        <name evidence="4" type="ORF">ESY86_14710</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2 3">Belongs to the peptidase S14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.92" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07017">
        <property type="entry name" value="S14_ClpP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00444">
        <property type="entry name" value="ClpP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001907">
        <property type="entry name" value="ClpP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023562">
        <property type="entry name" value="ClpP/TepA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381">
        <property type="entry name" value="PTHR10381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00574">
        <property type="entry name" value="CLP_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00127">
        <property type="entry name" value="CLPPROTEASEP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0720">Serine protease</keyword>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD87919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="224" mass="24966" checksum="D51B82888461E1BC" modified="2019-11-13" version="1">MDYGKEFEKFAIKDQGISSTYYNNIINSMYPTNLTPNIIEERQMNAVSMDVFSRLMMDRIIFMGTGINDQVANIIQAQLLFLESTDSAKDIQIYINSPGGSVYAGLGIYDTMQLIKPDVATICTGMAASMGAVLLCAGTKGKRSGLTHSRVMIHQPLGGAQGQASDIEITAREIVTLKKELYDIIAKHSGQDFDKVYEDSDRDYWMKADKAKEYGMIDEVLKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH28</accession>
    <name>A0A5C6ZH28_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF4230 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_08710</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025324">
        <property type="entry name" value="DUF4230"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14014">
        <property type="entry name" value="DUF4230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="202" mass="22941" checksum="7CA6FE67E9FAE3D9" modified="2019-11-13" version="1">METFFIIIISVLLTLGAVTLLSQLSIKRRSNTQSVILLDKIKKVCKFITVEGDFAEIYHYEDVKSRFLKLVSSRKKALVVIKAKAHVGFDLSKIKMDADVKTKTVKLHHFPEPEVLSIETDLNYYDKKDGMFNRFVASDLTELHNEAKLHIMNKVPESGLFNIAKKEALESVLLIEGIVETIGWKLDYSALEIGSETQKLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH76</accession>
    <name>A0A5C6ZH76_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Sulfotransferase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_09770</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008146">
        <property type="term" value="F:sulfotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016051">
        <property type="term" value="P:carbohydrate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018011">
        <property type="entry name" value="Carb_sulfotrans_8-10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005331">
        <property type="entry name" value="Sulfotransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12137">
        <property type="entry name" value="PTHR12137"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03567">
        <property type="entry name" value="Sulfotransfer_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="239" mass="28918" checksum="B2EEF48D86601E8C" modified="2019-11-13" version="1">MKNILKKIMPSPFKERLLEYNRRRFCKNLYVTREQSNPGEYYSFNEFDYYKCIFIHIPKAAGISFNMSLFGNYGGGHRDLKFYEDKYPKWTFDSYYKFTVVRNPWDRLYSAYTFLKKGGFDHIDKQWAEENLSQLNSFEDFVMTWVNKENVYSKIHFMPQFEFLTDSDGKVYMDYIGRFEAIEDSFEVIARYLKIDTSLEKRNLTNNKASYHKHYTDVMIQIVADVYERDIEEFGYTFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHF7</accession>
    <name>A0A5C6ZHF7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Abhydrolase domain-containing 18</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_10290</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000801">
        <property type="entry name" value="Esterase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00756">
        <property type="entry name" value="Esterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="234" mass="27474" checksum="4F6CAEA85E248388" modified="2019-11-13" version="1">MKEDYHKWYSPTLSKDIEMLIFGHAGYPVILFPTTSGRFYECRDFKLIDSARWFLEAGIIQIYCPDSINELSWYDKNMHPADRVKNHMWYDKFILDEVVSSICIEKGLDKVAVAGVSFGGYHAANFAFKHPEKVSHMFSLSGSFDIKSFMDGYYDDNVFFNNPVDFLPGSNHPDLWNMNIILGVGEWDICLEANQRLAKILSDKNIPFWFDERKWAEHDWPIWRQMFPHYLSTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHF8</accession>
    <name>A0A5C6ZHF8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GMP synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GATase" evidence="1">
        <location>
            <begin position="34"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="272" mass="31410" checksum="CF0BBD93B5669EF5" modified="2019-11-13" version="1">MKKAHVKLAILDMNNGEPNQGLRCIKEIVTLFEEDVDYQIFDVRSKQELPDSSFDIYISSGGPGSPLDKGAWRKPYLHLMQELWDFNKQSDYQKKHVFFICYSFQVMCDYFELGSIKPRRSTSFGILPIHKTKAGLKDTLLEGLSDPFFAVDSRDWQLIQPRLKVFKEHGASILSLEKLRSHVEYERAIMAVRFSKEFVGTQFHPEADPIGMKAYFLAEENKRKVITNFGEEKYENMMTQMDDPEKITLTYNTILPKFIGKAIKQVSASLIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHM9</accession>
    <name>A0A5C6ZHM9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Integration host factor subunit beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial histone-like protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030527">
        <property type="term" value="F:structural constituent of chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000119">
        <property type="entry name" value="Hist_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010992">
        <property type="entry name" value="IHF-like_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33175">
        <property type="entry name" value="PTHR33175"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00216">
        <property type="entry name" value="Bac_DNA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01727">
        <property type="entry name" value="DNABINDINGHU"/>
    </dbReference>
    <dbReference type="SMART" id="SM00411">
        <property type="entry name" value="BHL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47729">
        <property type="entry name" value="SSF47729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="96" mass="10500" checksum="C23B3C57E91CF13C" modified="2019-11-13" version="1">MTKADIVAKISDRLGMEKGDVQATVETFMEEVKSSLEGGDNVYLRGFGSFIVKTRAEKTGRNISKNTTIKIPAHNIPAFKPAKVFVEGVKTNVEVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHN2</accession>
    <name>A0A5C6ZHN2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11195</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="130" mass="14981" checksum="9FA79F064C5F3E9B" modified="2019-11-13" version="1">MNFALFHKITAYILVFMLCFQNVNTLFIVGDFMVNQALIAKTLCVQKENQQGCNGKCQLRKELSENTQTSKPEAPAQDYKRLTLDVFYLSENLHDSQVFCLRSRKENIKLATPKLCKLYLDIDTPPPNFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHN6</accession>
    <name>A0A5C6ZHN6_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA pseudouridine synthase B</fullName>
            <ecNumber evidence="4">5.4.99.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridine(55) synthase</fullName>
            <shortName evidence="4">Psi55 synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridylate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA-uridine isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 7" type="primary">truB</name>
        <name evidence="7" type="ORF">ESY86_13870</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>uridine(55) in tRNA = pseudouridine(55) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:42532"/>
            <dbReference type="Rhea" id="RHEA-COMP:10101"/>
            <dbReference type="Rhea" id="RHEA-COMP:10102"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="EC" id="5.4.99.25"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.25" evidence="4"/>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106029">
        <property type="term" value="F:tRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02573">
        <property type="entry name" value="PseudoU_synth_EcTruB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01080">
        <property type="entry name" value="TruB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002501">
        <property type="entry name" value="PsdUridine_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014780">
        <property type="entry name" value="tRNA_psdUridine_synth_TruB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032819">
        <property type="entry name" value="TruB_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13767">
        <property type="entry name" value="PTHR13767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16198">
        <property type="entry name" value="TruB_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01509">
        <property type="entry name" value="TruB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00431">
        <property type="entry name" value="TruB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TruB_N" evidence="5">
        <location>
            <begin position="36"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="TruB_C_2" evidence="6">
        <location>
            <begin position="186"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD88182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="229" mass="25620" checksum="30BBB82E5DE81D6F" modified="2019-11-13" version="1">MSTAEDFQNGQVLLIDKPLHWTSFQAVNKLRWEIRQAFNIKKIKVGHAGTLDPLATGLLIICTGKMTKQIDSFQGQDKEYTGTFVLGSSTASYDLETEIDKTFPTEHITEDKIHATTKKFIGDIDQFPPVFSALKKDGKRLYEYARAGEAVEIKSRRVHISAFDITHIEGNAVDFKVVCSKGTYIRSLAHDFGKALDSGAHLSALRRTKIGEFDVKDAVLPEDFIARLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHQ6</accession>
    <name>A0A5C6ZHQ6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">BlaI/MecI/CopY family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BlaI transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005650">
        <property type="entry name" value="BlaI_family"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34134">
        <property type="entry name" value="PTHR34134"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03965">
        <property type="entry name" value="Penicillinase_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019455">
        <property type="entry name" value="CopR_AtkY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="121" mass="14322" checksum="84D174261450B7D7" modified="2019-11-13" version="1">MQLSKTEEQLMQYLWKRERAFMKDLLDAYPNPKPATTTVATLLKRMIGKGFVAYKLYGKSREYYPLVQKKDYFSKYVNAMIKTFFNDSASQFASFFTKETDLSKEELEDLKRLIDSEIKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHR5</accession>
    <name>A0A5C6ZHR5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">SulP family inorganic anion transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_13150</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008271">
        <property type="term" value="F:secondary active sulfate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001902">
        <property type="entry name" value="SLC26A/SulP_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11814">
        <property type="entry name" value="PTHR11814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="9"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="34"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="58"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="82"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="157"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="192"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="255"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="337"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="387"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="Sulfate_transp" evidence="6">
        <location>
            <begin position="5"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD88454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="530" mass="57083" checksum="56296F5060C4E457" modified="2019-11-13" version="1">MFKTLKSDFPASVVVFFVALPLCLGIALASGAPLFSGLIAGIIGGIVVGALSGSKVGVSGPAAGLAAIVLTAIGTLGGYENFLVAVVLGGVIQLVFGILKAGIIGYYFPSSVIKGMLTGIGIIIILKQIPNFFGYDEKSAWDLGFFENDGGNTFSEILAIVNNITPGAALIGIVSLLLLILWDKVLTKKSKVFQIIQGPFVVVVLGILFYTITQNSETLFLGEKHMVNVPIPDDIQSFMGQFSFPNFAVITNMEVWIVAFTIALVASLETLLCVEATDKIDPEKNVTPTNRELLAQGTGNILSGLIGGLPITQVIVRSSANIQSGGKSKLSPILHGFLLLIAVVLIPRLLNMIPLSVLAAILLVVGYKLAKPALFKKMYKLGWKQSVPFAVTVGGIVFTDLLIGIGLGLGVGIVVILIKSYQNSHFLHVEDKSNGKHKIKMTLAEEVTFFNKGAILKELDSLPRDSYLEFDVTKTRYLDHDIIEILEDFAFKAKERNIDIKLISKRGVIENPESFTEFFKLRPKSKISLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHV9</accession>
    <name>A0A5C6ZHV9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetylmuramic acid 6-phosphate etherase</fullName>
            <shortName evidence="3">MurNAc-6-P etherase</shortName>
            <ecNumber evidence="3">4.2.1.126</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">N-acetylmuramic acid 6-phosphate hydrolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">N-acetylmuramic acid 6-phosphate lyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">murQ</name>
        <name evidence="5" type="ORF">ESY86_11000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D-lactate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>H2O + N-acetyl-D-muramate 6-phosphate = (R)-lactate + N-acetyl-D-glucosamine 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:26410"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16004"/>
            <dbReference type="ChEBI" id="CHEBI:57513"/>
            <dbReference type="ChEBI" id="CHEBI:58722"/>
            <dbReference type="EC" id="4.2.1.126"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-sugar metabolism; N-acetylmuramate degradation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="3">A lyase-type mechanism (elimination/hydration) is suggested for the cleavage of the lactyl ether bond of MurNAc 6-phosphate, with the formation of an alpha,beta-unsaturated aldehyde intermediate with (E)-stereochemistry, followed by the syn addition of water to give product.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GCKR-like family. MurNAc-6-P etherase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.126" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00342"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016835">
        <property type="term" value="F:carbon-oxygen lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046348">
        <property type="term" value="P:amino sugar catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097173">
        <property type="term" value="P:N-acetylmuramic acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd05007">
        <property type="entry name" value="SIS_Etherase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00068">
        <property type="entry name" value="MurQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005488">
        <property type="entry name" value="Etherase_MurQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005486">
        <property type="entry name" value="Glucokinase_regulatory_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040190">
        <property type="entry name" value="MURQ/GCKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10088">
        <property type="entry name" value="PTHR10088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10088:SF5">
        <property type="entry name" value="PTHR10088:SF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00274">
        <property type="entry name" value="TIGR00274"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01272">
        <property type="entry name" value="GCKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="1 3 5" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SIS" evidence="4">
        <location>
            <begin position="53"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD88761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="274" mass="29817" checksum="7D14D061B11EF66E" modified="2019-11-13" version="1">MTFIKTTEQASNYDHLEKMTVNELLGHINKEDQCVPIAVEKALPQIKALVAQIVNKLKNAGRLFYIGAGTSGRLGILDASECPPTFGVAPEMVIGIIAGGDLAIRNAVEFAEDSTTQGWLDLQFHKITAKDVVIGLAASGTTPYVVSALEACNQHDIITGCVTCNQDSPLAKTSNFPIEVIVGPEFVSGSSRMKAGTAQKLVLNMISTSVMIQLGRVKGNRMVDMQLSNTKLVERAVTMLMQELNIEKEEAQTLIKRHKNVRTALMNYKDGRDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHW0</accession>
    <name>A0A5C6ZHW0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">VWA domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="677" mass="77590" checksum="9E4B7C1BF936A707" modified="2019-11-13" version="1">MQTQTLIYIILAILVALALALFQYIYKSKKQGKIYWFLAALRFMTVLSILLLLINPKFDSVTYYNEKPNLLIAVDNSESVAYLKQDTKAKALLETLRQDEALNERFDLEFYSFGKELIPLDTLAFNEKQSNLAKVFERFSEVFNNAVSPTVLISDGNQTYGSDYVYLAKKYKHPIFPVILGDTTRFADLKIEQLNVNRYAFLKNKFPVEIIANYSGTSAINTQLKVSSGTATVFSKPLSFSKDNTSQIVNFNLPANRVGIGTYKAELLPMDNEQNTINNVKNFAVEVIDQKTNVAIVSEIIHPDLGTFKKAIERNEQRQASILNVQEFLKQSNDFQLVIAYQPTNDFKLLFEEVDRLKLNKIVVAGTNTNWSQLNKIQTNYKQQITNQTEEFQPTLNQNYGAFIVDDLNFEDFPPLKSEFGETNFLVPTETILYKTINGIQIDEPMIATFEVNERREALILGEGIWRWRAQTYFDEGSFNNFDDFVGKLVQYLSSNKRRSRLNVNYESFYNGNENVILSAQFFNKNYEFDANANLEILLDNKDTDKTTRIPFVLNTTNYQVDLSGLEAGDYSFKVNVASENISKAGDLKILDYNVEQQFLNANVSKMETIAMDTDGRSYFIDQTNAFTSDLLNDSRFAIVQKSSKNVVPLIDIKYLLALMMFCLFAEWFIRKYNGLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIE5</accession>
    <name>A0A5C6ZIE5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uracil phosphoribosyltransferase</fullName>
            <ecNumber evidence="1">2.4.2.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_07830</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.9" evidence="1"/>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004845">
        <property type="term" value="F:uracil phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="219" mass="24504" checksum="9C233ADC37FCCD0F" modified="2019-11-13" version="1">MHIHDLSKHNSILNSFIADLRDVNIQKDRMRFRRNIERIGEVLGYEMSKTLQYKDKTVVSPLGEKQTSLYQNEIVLCSILRAGVPLHNGLLNYFDDAENAFISAYRHHKQTPETFEIIVEYLACPSLEGKTLILADPMLATGQSMVATFEALRPFGKPKNIHIVSVIGAQPGVDLISKHFSQDTHLWIAAVDEDLSDKGYIVPGLGDAGDLAFGNKLQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIF0</accession>
    <name>A0A5C6ZIF0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2271 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08910</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014469">
        <property type="entry name" value="DUF2271"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10029">
        <property type="entry name" value="DUF2271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022828139" evidence="1">
        <location>
            <begin position="21"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="161" mass="18396" checksum="3C8A35A426ADE936" modified="2019-11-13" version="1">MKTIFKIIPAILLTGFLLTAFTTTENKAVKCLIQMTNYTGEGAYVIVSLLNPSGDYEETLYVQGKDSEWYSEIPEWWKFYGKYRPNIDAISGATISGGERTVTVLQIPEDKIDKGYSLRFETSVEDQDYYAADIQFELTTENLKAKKEGKGFIRYIRMLPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIG8</accession>
    <name>A0A5C6ZIG8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Dicarboxylate/amino acid:cation symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_11760</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046942">
        <property type="term" value="P:carboxylic acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001991">
        <property type="entry name" value="Na-dicarboxylate_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018107">
        <property type="entry name" value="Na-dicarboxylate_symporter_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036458">
        <property type="entry name" value="Na:dicarbo_symporter_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00375">
        <property type="entry name" value="SDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118215">
        <property type="entry name" value="SSF118215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00714">
        <property type="entry name" value="NA_DICARBOXYL_SYMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0769">Symport</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="43"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="239"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="279"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="387"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="412"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD88711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="480" mass="52092" checksum="92780B59F2DB3F13" modified="2019-11-13" version="1">MKKLALHWKIIIGMVLGIIWALLSSTMGWSAFTINWIDPFGTIFINLLKLIAVPLVLFSIIGGVANIGDPSSLGRMGGKTLGIYLLTTIMAISLGLLLVNTFKPGKLIDEQSRIDNRISYEIWADSQGYEIKDGISYLKDPAFMKRAQEISDLSNAELKDAAVQDKMESAEKGKETTPLQPLVDIVPDNFFHSLSTNGLMLQVIFFAVFFGVCLLFIPTEKSQPVLNIVDGINEVFLKMVDLVMQAAPFFVFALLAGVVSKMAGDDIGKVVEIFKGLSWYSLTVLAGLLLMIFVIYPVILKVFVKKIPYGGFFKSMGPAQTLAFSTSSSAATLPVTMECVEQNLGVNKKVSSFVLPIGATVNMDGTSMYQAVAVIFLAQLHMIDLTIGQQVTVVLTATLASIGSAAVPSAGLVMLIIVLDSVGLNPAWIAIIFPVDRILDMFRTVVNVTGDATVCSIIADGENMLDYKEKDPTETFDLDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIJ5</accession>
    <name>A0A5C6ZIJ5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peroxiredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_06425</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024706">
        <property type="entry name" value="Peroxiredoxin_AhpC-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019479">
        <property type="entry name" value="Peroxiredoxin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10417">
        <property type="entry name" value="1-cysPrx_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000239">
        <property type="entry name" value="AHPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="5">
        <location>
            <begin position="3"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate" evidence="4">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000239-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD89961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="215" mass="24189" checksum="87A48A008AACA7D8" modified="2019-11-13" version="1">MMALVGKQFPDINVNAMNDMGDTFKLNVLEEAVNNKKKVVLFWYPKDFTFVCPTELHAFQSAIKEFEKRNTLVIGASCDTPEVHFAWLSTAKDNGGIEGVTYPILADSNRNLSSVLGILDIQNEVYDEKTDSMQVEGDNVTYRATYIIDEEGKIVHESVNDMPLGRNVNEYLRLIDAYTHVQEKGEVCPANWEDGQAAMQPNANSTKEYLKAQLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIK4</accession>
    <name>A0A5C6ZIK4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">dTDP-4-dehydrorhamnose reductase</fullName>
            <ecNumber evidence="2">1.1.1.133</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rfbD</name>
        <name evidence="4" type="ORF">ESY86_07980</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>dTDP-beta-L-rhamnose + NADP(+) = dTDP-4-dehydro-beta-L-rhamnose + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:21796"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57510"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:62830"/>
            <dbReference type="EC" id="1.1.1.133"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate biosynthesis; dTDP-L-rhamnose biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the dTDP-4-dehydrorhamnose reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.133" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00124"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008831">
        <property type="term" value="F:dTDP-4-dehydrorhamnose reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019305">
        <property type="term" value="P:dTDP-rhamnose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005913">
        <property type="entry name" value="dTDP_dehydrorham_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029903">
        <property type="entry name" value="RmlD-like-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10491">
        <property type="entry name" value="PTHR10491"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04321">
        <property type="entry name" value="RmlD_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01214">
        <property type="entry name" value="rmlD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="2 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RmlD_sub_bind" evidence="3">
        <location>
            <begin position="4"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU364082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="283" mass="31700" checksum="14ED694126D62DB5" modified="2019-11-13" version="1">MATKILVTGATGQLGQTFQEKSKATPDHLEFVFVSRADLDITNSEAINAFFSTHDFDYCINCAAYTNVELAESEPDQAYKINAEAVKSLAEVCEIHNTILVHISTDYVFDGSKTSPYNETDQTNPLNAYGASKLKGEQYIAELLSNYFIIRTSWLYSPYGKNFAKTIASKLQNNEPLKIVTSETGTPTSCADLAEFILFLITNKTEDFGLYHFSASGETTWYGFAQQIAKKLNKTELVSPVDSFPVKAKRPRYSVMDNQKANNLMQKSFDWRNSVDAVIDQLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIR3</accession>
    <name>A0A5C6ZIR3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_04745</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="267"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="353" mass="41467" checksum="1D9921175C3F391B" modified="2019-11-13" version="1">MEEKLILKKKPVYPITDALSKYLTVEGRNINIPVFYDDLLRFQGGVNILDDNDKDTLWLSCYYSEFEREELELSLKQMYSILHSDGSDSILPYLSIDSIDFCTFGNTKPFRVKVRNILNDNYMFIYVKKADASRIYGLELEHILSPNHINFLVHKDTLIEDHILGIPGDIFIEEHLDTISEQDKRALAKEFVKFNERCFVRLLADMRSYNYVIVITHDFDRIQYRIRAVDFDQQSYEGNPKVYRLQFLKENNALVKMSLDVLAKESIEQYKKEERSLLAKRATSEKERLQELIKCMSEDSISSLEKVKELRRGLYQLTNDVNFKKAVNMGELLNAALDFIIRNYQSENPYIIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIU6</accession>
    <name>A0A5C6ZIU6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_05030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="121" mass="14040" checksum="66215DE91827AC36" modified="2019-11-13" version="1">MKKETINIDHRKKIFKAQLNGVGFKEGDAHIIYLPSLQISSYGECIEEANEMMKISLNEFSENLLQLDELKINSILKQLGWEKAKFFDKRLVHLSETTFEDIKKEFNLPDDTQVQKIPIAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIX9</accession>
    <name>A0A5C6ZIX9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Lycopene cyclase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_06530</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="383" mass="44710" checksum="21A104CC3107DF33" modified="2019-11-13" version="1">MTKTSKHYDYVIIGNGLSGLQLALKMAKDVYFNSMRIALIDPSEKDENDRSWSFWEIGKGQWDAIIHKSWDHAIFQSSQQKALLDLAPYHYKTIRSIDFYEHAKTKLSAKANFNFILEKVLSVVESETSLITTDKNQYTANHIFDSRMPEAYFSTEANKSIKILQHFKGLVIKTERPKFETSAITMMDYRLKDGEQTTFTYVLPFSETEALVEFTYFTAETVPESTYDKYLEHYISEYLKIEDYQILEVETGVIPMTNFPFDSYSTKHLTKIGTAGGWVKGSTGYSFKLTEKKVTRIIENIKASRNPSEGLFRNKYKVYDKIFLKVLSEENEKGEWIFERFYTKNKVQTMFRFLDEESTFAEELSIMSSLFSWSFIKAFFKTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ05</accession>
    <name>A0A5C6ZJ05_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_09550</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="210" mass="23935" checksum="B14316CF5D10A6BD" modified="2019-11-13" version="1">MILGSLGEHDDFLLQSDYNGVAFPMYSNPIKLSATLVNFGKESENAFLKAQERQSKELAINFNDSIQNKSQYVKLQISDRLELITSLNNSDNEDVFEFIKNNKDVHAITSLAIALNQEDLDKIAKTDELFLEASGIKTYSLNLYNDGKFQQKINFNDGVVFAYQTSKCCWKENDRHQVEIVDLVEGNDNCPNGSYTSAKRAKKKINYYKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ28</accession>
    <name>A0A5C6ZJ28_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2029 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_09020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="235"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="291"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="352"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="385"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="417"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="446"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="474" mass="54659" checksum="0BAFB233680A4F89" modified="2019-11-13" version="1">MFKYDTLKLYKFPILIALSSMAFYFSFAYDLERSNHTKLLTLYVGLWVAFYFLLKFAKHNLKLLTLLAFLFRALFILAIPNLSQDFYRFIWDGRMILAGINPYLFTPESVMNASNLPIAEAQQLYDGMGQLSATHFSNYPPLNQLCFSIAALFAGHSILGSVVVLRLLIIAADFGTLYFGRKLLRKLKLPEHHIFWYILNPFIIIELSGNLHFEGLMVFFLIWSLYLLHAGKWRWAAVLFACSISVKLIPLLFLPLFYGYFRKPEKRAQLENQVDKTIPVLKIRAISLKKLIAFYGSVGAVTLLLFSPFFSWEFVHNYSETVALWFNNFEFNASLYYLARQLGFWLSGYNEIAVIGKIFAVLVFLSVMSLAALRSRKDTKVLIGQMLFAFAIFLFFSTTVHPWYLATLLLLSVFTTYKFPLIWSAVVMLSYFAYSTGSESGSSENLLIIAIEYIVVFGVLIWELFFKRVKEGFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJK6</accession>
    <name>A0A5C6ZJK6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_05150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="119" mass="13418" checksum="EAFB6A25F485C083" modified="2019-11-13" version="1">MELLIYSRTYAEADAMRNFIDFYYSLHMTHLASDLLAKGLSPKQISDAVLKATKIANALGVEVHKHFRPVFSGIRQDIIQDCKLSDLGFGLVLMNADTSLSVVGEFQMNVLKKYLDSRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJQ6</accession>
    <name>A0A5C6ZJQ6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF3307 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03505</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021737">
        <property type="entry name" value="Phage_phiKZ_Orf197"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11750">
        <property type="entry name" value="DUF3307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="239" mass="27170" checksum="77A4F052BB7CF256" modified="2019-11-13" version="1">MLSLFIKLILAHLIGDFLLQPEKWAKHKAKHKLGSKYLYWHLLVHAIALLVVLQFNVEYWLAFCIIISSHFFIDVAKAQFKTKKNSRLLFALDQLAHLSVIALVVEVYTPYLNKISAIDYNQALLLTASIIAVTSTSSIIMKTIISKWNIDEDAGKEHSLEHAGAYIGILERLFVFLFVVLQFWEGIGFLLAAKSIFRFGDLSRSKDRKLTEYVLIGSLISFGLAMLIGLLYLKIAREL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJQ7</accession>
    <name>A0A5C6ZJQ7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Succinate dehydrogenase cytochrome b subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011138">
        <property type="entry name" value="Cytochrome_b-558"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034804">
        <property type="entry name" value="SQR/QFR_C/D"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81343">
        <property type="entry name" value="SSF81343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02046">
        <property type="entry name" value="sdhC_b558_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="222" mass="25124" checksum="A3A9FF95401F68DF" modified="2019-11-13" version="1">MAINQHFFRKTIIAGSGLFLCVFLVVHLSANLILVLPAAIARGLYNSYSTVLRESLFIQIIAYLLYASILLHVIYALLITLKNRKAKPQKYALNHYKQNSTWTSQNMGFLGTMILLFIVVHLANFWARIKLGLGAPVGLDAAGYQDVYEITNSLFHNIYFVCFYTLMAIPLGFHLHHGFKSAFKTLGFYHKKGLRIIANVALWYALIIGIGFGIIPFIVYFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJU0</accession>
    <name>A0A5C6ZJU0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GIY-YIG nuclease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07385</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035901">
        <property type="entry name" value="GIY-YIG_endonuc_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01541">
        <property type="entry name" value="GIY-YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82771">
        <property type="entry name" value="SSF82771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GIY-YIG" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="74" mass="8975" checksum="803913758EF5ADF8" modified="2019-11-13" version="1">MNHCVYILYSEKLDRFYVGYTSNLDLRLIFHQNPEQRKYTHNAKDWALYHKIDCSSKRQGLSIETHIKRMKSKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK04</accession>
    <name>A0A5C6ZK04_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Deoxyuridine 5'-triphosphate nucleotidohydrolase</fullName>
            <shortName evidence="4">dUTPase</shortName>
            <ecNumber evidence="4">3.6.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">dUTP pyrophosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">dut</name>
        <name evidence="6" type="ORF">ESY86_07715</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>dUTP + H2O = diphosphate + dUMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10248"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61555"/>
            <dbReference type="ChEBI" id="CHEBI:246422"/>
            <dbReference type="EC" id="3.6.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4">Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the dUTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.23" evidence="4"/>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00610">
        <property type="reaction ID" value="UER00666"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004170">
        <property type="term" value="F:dUTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006226">
        <property type="term" value="P:dUMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046081">
        <property type="term" value="P:dUTP catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07557">
        <property type="entry name" value="trimeric_dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00116">
        <property type="entry name" value="dUTPase_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008181">
        <property type="entry name" value="dUTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029054">
        <property type="entry name" value="dUTPase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036157">
        <property type="entry name" value="dUTPase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033704">
        <property type="entry name" value="dUTPase_trimeric"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11241">
        <property type="entry name" value="PTHR11241"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00692">
        <property type="entry name" value="dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51283">
        <property type="entry name" value="SSF51283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00576">
        <property type="entry name" value="dut"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 4" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="dUTPase" evidence="5">
        <location>
            <begin position="11"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="63"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="80"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD89661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="143" mass="15495" checksum="C542869D744046B2" modified="2019-11-13" version="1">MKIKIINKSNHELPKYETAASAGMDLRANLSESRTLKPLERSIVGTGLFIELPLGYEAQVRPRSGLAAKNGITVLNAPGTIDADYRGEIGVILVNLSNDAFTIQNGERIAQMVIAKHERAQWDNVDELSETDRGEGGFGSTGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKH6</accession>
    <name>A0A5C6ZKH6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase family 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="3"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="296" mass="34466" checksum="42D60015D4472BA4" modified="2019-11-13" version="1">MLSVLIPVYNYDVRALVTRLHKQLALAAIRFEIICIDDFSDPEMSQINAEIVQLPHTTYEISNRNAGCDATRQTLAIWANYDWLIFLDADVMPVSEDFISNYLKFTTSEYDAIYGGITYKPEKPESNLMLRWEYGNAKENVPASARNRKPYKMLVTANFMIRKTIFLKLNSKIEYKGYGYDIYLGALLKSNSFKVFHIDNEVYHLGLEPNATYLNKVEEAVDNLLKLNQEGKLKKTENSLLNTFERLKYCKLNHYVAWTFRRSKKQLTINLLSARPNITLLQYYKLGYICEQDLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKU0</accession>
    <name>A0A5C6ZKU0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter permease subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_04460</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90626.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032688">
        <property type="entry name" value="ABC2_membrane_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12679">
        <property type="entry name" value="ABC2_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="60"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="111"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="177"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="246"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD90626.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="274" mass="32064" checksum="1710C4A77BFB589B" modified="2019-11-13" version="1">MLRLLKLELQKLLLNRASKILIFISFILPFFVIILSSLRINFFGLFVLELGHYGLFNFPIVWHITTFFAAQFKFFFAIVVVSMIGNEYSNKTIKQNLIDGLSKKEFILSKFYTIVFFSAVATVLIFIICLSIGLYYSSISEVALIFRETEFLLAYFVKLVGFFSLCLFLGMLVKRSAFALAFLFMLFIVEWILYGLMAWKLDENTADRIQNFFPLKSMWKLIDQPFQRIAISKMPDSKALIYDFAVHWYEVAIVLGWTAIFIFLSYRLLKQRDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKX4</accession>
    <name>A0A5C6ZKX4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">MurNAc-LAA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_03765</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008745">
        <property type="term" value="F:N-acetylmuramoyl-L-alanine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02696">
        <property type="entry name" value="MurNAc-LAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002508">
        <property type="entry name" value="MurNAc-LAA_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008756">
        <property type="entry name" value="Peptidase_M56"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01520">
        <property type="entry name" value="Amidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05569">
        <property type="entry name" value="Peptidase_M56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00646">
        <property type="entry name" value="Ami_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="MurNAc-LAA" evidence="2">
        <location>
            <begin position="352"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="470" mass="53360" checksum="4125567457E2AAF1" modified="2019-11-13" version="1">MMDYAIYTILSLGLSFLVFQLVLRQQKTFGFNRFFLLASLLCCLLAPLTELNVFNSVPRIHDITSQFSEEKIIIAEDLEGITVETLTANSFGFFDALLGLYIAISLCFLFRLLGNLYRIAKHTKSTHVQYAGLKLIKTEEDQEASSFFKYVFIPSEVWNNKELFNNIIQHESAHYKQAHVLDIICVELLLCVFWFNPFLWFYKSAILQNHEYLADVHVINSGIAAEAYSKSIIYSTVQKYRMPLASGFNFKPIKNRILMLQKSKSSVLKRSLKISAALLLLSGIFMISSFETSTKPLLVVVDVAHGGHDSGNSMEKDVVLSIANYLAAYSNDDLKIVFTRTSDQFLSLKERVDFINQQKPDVMISLHCNAHSNVETSGVEAFYYPDNKHQETAYNYSKILIANQLGLFSQRGEIKNAGFYVLKNTDAPSVVLELGFITNAKDRATLTDKKQQQAIAKNLYESLLNIQKNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKY6</accession>
    <name>A0A5C6ZKY6_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 13 14">UDP-N-acetylmuramoylalanine--D-glutamate ligase</fullName>
            <ecNumber evidence="5 13 14">6.3.2.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">D-glutamic acid-adding enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13 17" type="primary">murD</name>
        <name evidence="17" type="ORF">ESY86_09380</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 14">Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13 14">
            <text>ATP + D-glutamate + UDP-N-acetyl-alpha-D-muramoyl-L-alanine = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</text>
            <dbReference type="Rhea" id="RHEA:16429"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29986"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83898"/>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 13 14">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 13 14">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the MurCDEF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.9" evidence="5 13 14"/>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008764">
        <property type="term" value="F:UDP-N-acetylmuramoylalanine-D-glutamate ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00639">
        <property type="entry name" value="MurD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005762">
        <property type="entry name" value="MurD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01087">
        <property type="entry name" value="murD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 13 14" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="8 13 14" id="KW-0132">Cell division</keyword>
    <keyword evidence="9 13 14" id="KW-0133">Cell shape</keyword>
    <keyword evidence="12 13 14" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13 17" id="KW-0436">Ligase</keyword>
    <keyword evidence="13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10 13 14" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase_M" evidence="16">
        <location>
            <begin position="108"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="15">
        <location>
            <begin position="307"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="110"/>
            <end position="116"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00015655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="TXD89309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="445" mass="49634" checksum="0789EA80AD1A833E" modified="2019-11-13" version="1">MGFYLGILGAGESGIGTALLAKANGYEVFVSDKGSIKEKYKQVLIQHEIEFEEGKHSEEKILNANLIMKSPGIPDKADLVKQIRAKGIPVISEIEFASRFTNAILVGITGSNGKTTTASLTHHLLKQELEVGLAGNIGESFAKQILDKDYPNYVLEISSFQLDDIESFKPHIAVLLNITPDHLDRYDYQFENYIASKFRIAENQTAEDYLIYDADDEVITTWLEAHPVQSTLIPFSLKKTIENGAFLDNNNTIIITVDNNQITMSAANLALEGKHNIKNAMAASTVAHLLKIRKQTIRESLENFQGVEHRLENVLKINKVQYINDSKATNVNATYYALDSMDGPTVWIVGGQDKGNNYQELFQFVNEKVKAIICLGVDNQKLMENFGNMVDTIVETQFMSEAVKIAYKIAESGDSVLLSPACASFDLFENYEDRGRQFKDAVRNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKZ5</accession>
    <name>A0A5C6ZKZ5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PadR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005149">
        <property type="entry name" value="Tscrpt_reg_PadR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03551">
        <property type="entry name" value="PadR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PadR" evidence="1">
        <location>
            <begin position="15"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="113" mass="13021" checksum="67E5ED64D9E063A5" modified="2019-11-13" version="1">MANSKLYKGSLVTIILRLLKENEKMYGYEITQKVKQITQGELQITEGALYPALHKLEAQGLLDVDVQKVGNRLRKYYKLTPQGQKETHSKLQELQAYIKTMQVLVNPKWSLES</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLG6</accession>
    <name>A0A5C6ZLG6_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">3-deoxy-D-manno-octulosonic acid transferase</fullName>
            <shortName evidence="8">Kdo transferase</shortName>
            <ecNumber evidence="3 8">2.4.99.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 8">Lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ESY86_02605</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP-Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>CMP-3-deoxy-beta-D-manno-octulosonate + lipid IVA (E. coli) = alpha-Kdo-(2-&gt;6)-lipid IVA + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28066"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58603"/>
            <dbReference type="ChEBI" id="CHEBI:60364"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:85987"/>
            <dbReference type="EC" id="2.4.99.12"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Bacterial outer membrane biogenesis; LPS core biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell inner membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the glycosyltransferase group 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.99.12" evidence="3 8"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00958"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043842">
        <property type="term" value="F:Kdo transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009244">
        <property type="term" value="P:lipopolysaccharide core region biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11720">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007507">
        <property type="entry name" value="Glycos_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038107">
        <property type="entry name" value="Glycos_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039901">
        <property type="entry name" value="Kdotransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42755">
        <property type="entry name" value="PTHR42755"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04413">
        <property type="entry name" value="Glycos_transf_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0448">Lipopolysaccharide biosynthesis</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycos_transf_N" evidence="9">
        <location>
            <begin position="42"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR639901-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU365103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD90869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="411" mass="46604" checksum="AFA4E0A15009AC5C" modified="2019-11-13" version="1">MYTFGIYIFRFILKSLSFFNEKIKKGVVGRRDTFAILEAAISKTDQTLWFHCASLGEYEQGLPVFELLRKDFPDHKIVLSFFSPSGYEIRKNSAIADVVVYLPIDTPVNAKRFMDLVRPSLSIFVKYDIWPNYLKALKKDHRSAVLISARFRKKQIYFQFYGSVLRKALFAFEHIFVQDEQSKQLLKAINYNQVSISGDTRYDRVSNQLQINNQLDFIAAFKAQSTCVVIGSSWPEDEAVLLPYINDNASEALKFIIAPHEIKKNHIRDILKNLKVKTLLFSEKEGKNLSEYSVLIIDSIGLLTKIYSYADLAYVGGAMGKTGLHNILEPAVFGTPIIIGHNHTKFPEAAAMIAEAAVTSVKNKHDLKTVLDRFLSSKPVMASEGKKNAHYIEAHSGAVEQIMAYLRLEGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLG8</accession>
    <name>A0A5C6ZLG8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Bifunctional purine biosynthesis protein PurH</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="8">Phosphoribosylaminoimidazolecarboxamide formyltransferase</fullName>
                <ecNumber evidence="8">2.1.2.3</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="8">AICAR transformylase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="8">IMP cyclohydrolase</fullName>
                <ecNumber evidence="8">3.5.4.10</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="8">ATIC</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="8">IMP synthase</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="8">Inosinicase</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">purH</name>
        <name evidence="10" type="ORF">ESY86_05785</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(6S)-10-formyltetrahydrofolate + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide = (6S)-5,6,7,8-tetrahydrofolate + 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:22192"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:58467"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="EC" id="2.1.2.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>H2O + IMP = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:18445"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:58467"/>
            <dbReference type="EC" id="3.5.4.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Purine metabolism; IMP biosynthesis via de novo pathway; 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide (10-formyl THF route): step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Purine metabolism; IMP biosynthesis via de novo pathway; IMP from 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide: step 1/1.</text>
    </comment>
    <comment type="domain">
        <text evidence="8">The IMP cyclohydrolase activity resides in the N-terminal region.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the PurH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.3" evidence="8"/>
    <dbReference type="EC" id="3.5.4.10" evidence="8"/>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00133"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003937">
        <property type="term" value="F:IMP cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004643">
        <property type="term" value="F:phosphoribosylaminoimidazolecarboxamide formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00139">
        <property type="entry name" value="PurH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024051">
        <property type="entry name" value="AICAR_Tfase_dup_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011607">
        <property type="entry name" value="MGS-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036914">
        <property type="entry name" value="MGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002695">
        <property type="entry name" value="PurH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11692">
        <property type="entry name" value="PTHR11692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01808">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02142">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000414">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00798">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00851">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52335">
        <property type="entry name" value="SSF52335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51855">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="5 8" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MGS-like" evidence="9">
        <location>
            <begin position="1"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD90247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="510" mass="55941" checksum="58BDADA0A0B3A5B7" modified="2019-11-13" version="1">MSNNKTIKSALISVFSKEGLEPIVKALDSQNVKIYSTGGTEKFIKDLGIEVIPVDEVTSYPSILGGRVKTLHPKVFGGILNRQENDSDQKELMEFDIPQIDLVIVDLYPFEKTVASGASNQDIIEKIDIGGISLIRAAAKNYADVVCVSSMEDYAEFLELLKSGNGSISEETRKHFAAKAFNVSSHYDSAIFNYFNKNHEIASFKISENQGQVLRYGENPHQKGYFFGDFDAMFDKLHGKELSYNNLLDVDAAVNLINEFKGEKPTFAILKHNNACGFAQRDSIHQAYVDALAGDPVSAFGGILIANTEIDKATAEEIHNLFCEVVIATSFSSEALEILKGKKNRILLILKDAPLAETTVRTCLNGVLVQEKDSKTDAPEDLTYATTSKPNASELDDLIFASKLCKHTKSNTIVLVKNKQLCASGTGQTSRVDALNQAIHKALSFKFDLQGAVMASDAFFPFPDCVENAHKVGISAVIQPGGSIKDQLSIDYCNDNEVSMVMTGIRHFKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLJ2</accession>
    <name>A0A5C6ZLJ2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phenylacetic acid degradation bifunctional protein PaaZ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">paaZ</name>
        <name evidence="5" type="ORF">ESY86_01880</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002539">
        <property type="entry name" value="MaoC-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011966">
        <property type="entry name" value="PaaN-DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01575">
        <property type="entry name" value="MaoC_dehydratas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02278">
        <property type="entry name" value="PaaN-DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="3">
        <location>
            <begin position="53"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="domain" description="MaoC-like" evidence="4">
        <location>
            <begin position="540"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="463"/>
            <end position="488"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="833" mass="93435" checksum="03F9BF1314AB9F38" modified="2019-11-13" version="1">MNKIQHYIQGNWTTGTEEGTPIHDAITGEAFTSIAIEGLDIPEILNYGRTKGGEKLRKMTFQERGNMLKSLAFYLTKRKEEFYELSYRTGATRKDSWVDIEGGFGNLFANASLRKLFPNQAYHVEGEPIDLSRGGRFMAHHIMVPKKGVAVHINAFNFPVWGMLEKCAVNWMAGVPAVVLPAPSSSYLAEAVARSIIASGILPEGALQIINGTVKNILDTVESQDVVTFTGSAKTGRLLKAHPRLIQESVPFTMEADSLNASVLGEDAVPGTPEFDLFIKEVRNEMTSKCGQKCTAIRRVIVPEHLVEDVQISLGKALDKVTIGDPRLKEVRMGSLVSQQQVQAVRDSVADLAKEAQIVYGDLDTIETIGADAKKGAFISPILLRADHPFQNSIIHEREAFGPVSTIMPYKNLDEAIQLAQMGKGSLVSSIATNDDKIAKDYVINAASHHGRILVLNRESAKESTGHGSPLPYLVHGGPGRAGGGEEMGGMRGIKHYLQRTAIQGSPSTITEITGIYQQNSKYKEAEQHPFKYHWEDIEPGMSLKTHNRTFTDTDIINFANLTWDHFYAHTDITSLDGSIFEHRTAHGYFIISAAAGLFVYPNKGPVAANYGLEECRFLRPLYHNDTVYVRLTCKQKVDRDVASAEHPSGIVKWYVEVFDALTDEKVAFATVLTMVQKKQEIFVELTSEKIEECLDNLFQDTKPKWGIMTPQHMIEHLEFTYKIASGEIQDFEVATPEKYLEKVHHSLYNYEKFPKGTNFPLLEKDKLEDLKYPDLQTAIDKFKAQREKYLEFFKENPDAKLKNLVFGELNRYESYLLERKHLSHHFEQFGLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLQ0</accession>
    <name>A0A5C6ZLQ0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05365</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="204"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="246"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="280" mass="31671" checksum="B8E93A9E2A68F3CA" modified="2019-11-13" version="1">MTATILLGIGLEYIDTVFQTIQNSSFSQYTIAGMKTLAVLFFLVNILKKYNEGIADKDGYTWGLSPGELMKNFAIVILVIFSTQVLGFFDSILVSVEAQYRGTAPALLPLQMQDIPIEEDIGLMDAAKNAMTLLYEALVTPLYGFKIFAFIIGIILWILDLFIYPLFLAERFFLLGIMQAFFPLVISLAVFEKFRSLAYTFFKLYAAVYMLVPAFFLVNIFVNALYTEINTNFWVNLFGTDVGEGFFAPVVQLGSVCFIVFLKFKLYKRATSFTLRLFTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLQ3</accession>
    <name>A0A5C6ZLQ3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_01175</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="162" mass="19094" checksum="B08853B6593E87C5" modified="2019-11-13" version="1">MIITVALVIMMCLVFVLVFLFVKTIDNRKWLTILVSLVITPFAYFYGAYPMINIFTNYHHQKYYSAEAWKEKPNLRYELSDDMIASKRLLGSSKAEIKQQLGPYEWLSWNNDNKAKNNNKWNYSLGIEPGAFNTQKECVEITFENQKLIRIQAFKEDIKFDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLR6</accession>
    <name>A0A5C6ZLR6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">T9SS type B sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_04455</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90625.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026341">
        <property type="entry name" value="Bac_Flav_CTERM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011041">
        <property type="entry name" value="Quinoprot_gluc/sorb_DH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50952">
        <property type="entry name" value="SSF50952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04131">
        <property type="entry name" value="Bac_Flav_CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023057824" evidence="1">
        <location>
            <begin position="21"/>
            <end position="1145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90625.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1145" mass="124929" checksum="074C0A0F4B229906" modified="2019-11-13" version="1">MKKIAALLLLTLLTTASTFSQQEASYWYFGKNAGLRFYAGAGTVIALTDGQIDTLEGCTSISDTEGNLLFYSDGQTVWNANHQIMDNANYFGGNGLLGDPSSTSSGLIVPKPQDPSKFYVFTVDEPHHQNANAYPNQFSGTYDGGGSVPQQDDGFNNGFNYSLVDMTLDGGLGDVDPTEKNVPLVSYDINDSEEIKYKCSEKITAVKADDCYSFWVITHFTNKFYAFKVDTDGVETTPVISTVGPNVPISGYRRNALGYLKASPDGTKLAVAHLGFATTQGANAPGGVYLFDFDNDTGIVSNALELYGPENNDSPYGVEFSAENKKFYASINAGPNGIGASQVIQWDLESDDVPASAIVIHQSNIFNAGALQLGLDKRIYRAQIDFSNSNSGRFLGVINNPELTGNAANYDETGVLLDVTGSSQNLGRIGLPPFIQSLFNSQIDIIKNGLSTTELNLCTGDNYMLIAEDIAGATYIWTQDGNPLAETSYQLMVDTPGFYEVFIEPNNGECPIEGNAVVGVFDIPTATQPDDLLVCADANTNNFDLSVKDLEILDGQAPEDYVVKYFTTEAQALLGQDEIMGNFYTTEALQTIYARVENRDNPNCYALTSFTFSVAEQAQIINLEDLTLCDTDFSGDAMDGFTSIDLSALAEGILGTQDAADFGITFHNSQADADNNVAAIAEVYANSNPNAEVIFVRVENTQKPKCYVTSSFTLTINNAPEAIDSTIIQCDEDGIPEGYTIFNLNEVFDAITNNAANRQIQFYETRADLENDNDEINADAFENYVSPQIIYALVTNTQTGCSNTAEVTLETSSTASNDTGLDACDDDGTEDGFYNFNLQDAEAAILFGLPTNLDLSYYETYDNALTETDALGNSFTNSTPYNQTIYTRVENANACFGISKIELIVYELPNLLPEETVYYCLNTFPQPITLSGGLIEGIPNNYYYEWSTGETTSEIEINAAGTYSVRVTTTDGCFKDRTISVLPSNIATITNIEITDASSNNSISVLVSGEGSYQYALDNPNGSYQDSNVFENVPFGFHTVYVRDVKNDCGIVDELVSVIGFPKYFTPNGDTHNPYWQVKGISSNFQPDSQILIYDRMGKLLRELDPLGPGWDGTWNGNNMPSSDYWFVVKLQDGRTFKGHFSLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLU4</accession>
    <name>A0A5C6ZLU4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carbohydrate binding family 9 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045670">
        <property type="entry name" value="DUF5916"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19313">
        <property type="entry name" value="DUF5916"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5916" evidence="1">
        <location>
            <begin position="229"/>
            <end position="810"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF19313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="818" mass="94045" checksum="0F8A1C06797005A4" modified="2019-11-13" version="1">MKTSIVFYIFFIWFSITIQAQQKKQLHIDRTSNPPKIDGVLDDSVWQTAEKAQDFTQFKPNAGIKDSIENRTVVQMTYDDEAVYLAAYLYDDPTKIMSQLTSRDDFGQTDFFGLILNPNNDAQNDTEFFVFSSGVQADATLTPSNGEDFGWNAVWDSAVKITEEGWVLEMKIPYRSLRFANREVQTWGIQFHRQFRRYRSQYTWNPIDISKGNTGLYHGELVGLKNIKPPTRLSFYPFTTGIVNSFEGRTETNLRFGMDVKYGISENFTLDMTLIPDFTQAGFDNLSLNLGPFEQTFSEQRQFFTEGVNLFNKGNLFFSRRVGSAPTGDTNLNANEIETNYPTTVKVLNAAKISGRTKNGLGIGFFNAITEKTFASLKDTLSGNSREQLVEPLSNYNILVLDQQFNQNSSVSIINTNVSRSGHFRDANVTAVIADITNKRNTYNLYAETKMSSVNRLDGTSTGYSSRFVASKIYGNYRYSFDHSFADTKFDINDLGLIYRNNYNNFGVDFGYRTFKPTKHFNSYNWSTYINYTRLDNPGVYTGNGLGASFNAATKETLHNFGARINLLPGKQFDYFEPRREGRYFIYENKMDARIYISTNYNNTFAIDANIGASVFFEDHRDTKQYSFGLEPRVRFNDKFFLVYEIDYDRISRDRGYTNNSNDLDNEIVFGQRDQETIINSIRGSYSFNPMHSLELTFRNYISTVDYDNQVYLLQDNGRLLKTTNSFSDLGLQSSNVNFSTWNLDLNYSWQFAPGSFLTALYRNQLLRRDAASDRAFDETISTLFQQPTLHSFSLRLQYFIDYNTAKNLFKRGTKSNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLY1</accession>
    <name>A0A5C6ZLY1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">M42 family metallopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_03250</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="8">Binds 2 divalent metal cations per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase M42 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008007">
        <property type="entry name" value="Peptidase_M42"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023367">
        <property type="entry name" value="Peptidase_M42_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05343">
        <property type="entry name" value="Peptidase_M42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001123">
        <property type="entry name" value="PepA_GA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="217"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="240"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="327"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR001123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001123-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001123-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD90397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="362" mass="40720" checksum="547A956BAA333094" modified="2019-11-13" version="1">MTKQSILNEKSLDFLEKYLNNASPTGYEWEGQKLWMDYLKPYVDEFITDTYGSAVGVINPKAKYKVVIEGHADEISWYVNYISDEGLIYVIRNGGSDHQIAPSKIVNIHTKHGIVKGVFGWPAIHTRDKTKEEAPKQENIFIDCGCNTKEEVEALGVHVGCVITYPDTFHILNKDKFVCRALDNRMGGFMIAEVARLLKENKKELPFGLYVTNSVQEEIGLRGAEMIAERIKPNVAIVTDVTHDTSTPMIEQKKEGDLQLGKGPVVAYAPAVQQKLRDLITETAEKKMIPFQRSALSRATGTDTDAFAYSNAGVASALISLPLRYMHTTVEMVHRDDVENVIRMIYETLLNIKGDETFSYFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM52</accession>
    <name>A0A5C6ZM52_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sigma-70 family RNA polymerase sigma factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_03115</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="10"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="3">
        <location>
            <begin position="106"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD90371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="169" mass="20068" checksum="1DC22149E88C20DA" modified="2019-11-13" version="1">MTQTDFTKLVLPFKDKVFRLAKRLLVSREEAEDATQEILIKLWKNNEKIKEYRNVEAFSMTMTKNFCLDRLKSKQAQNLKIVHSNYQDHNVSLQKDLENRDSVDWVSKIIEELPEQQKIILQLRDIEEYDYDEIAKVVDMNPTAIRVALSRARKTIREKLINTHQYGIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZML0</accession>
    <name>A0A5C6ZML0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SusF/SusE family outer membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_02830</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001070">
        <property type="term" value="F:starch binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025970">
        <property type="entry name" value="SusE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032187">
        <property type="entry name" value="SusF/SusE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14292">
        <property type="entry name" value="SusE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16411">
        <property type="entry name" value="SusF_SusE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023106953" evidence="1">
        <location>
            <begin position="20"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="domain" description="SusE" evidence="2">
        <location>
            <begin position="23"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="SusE" evidence="2">
        <location>
            <begin position="142"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="599" mass="64482" checksum="FF504A8FF1E469B4" modified="2019-11-13" version="1">MKITKFSALILSLFFVFMACETDDNVILTKPEAQFKLLSPGASNINLNYNLPDNPALTIVWEDELTAGSGGYMVELSSDNDFESPMVIGSSPSDSFTMTVAEFNSTVLGAGADAFEPFTVFLRVTSGSLVSNSVSFSVSSYSEAAPVVTSPDGSFNLVLLETTPTDTAISMSWDDPDFGENSSVAVNYEVQFAAGGTNFETIVAENAGAETTLEYTHEAFNEVVLNAGLAAEEAGDLDFRIKASIMMEGGNMERFSEPVNITVTPYSVELAPILYVVGAGAVDAGWSWDNPIELPLQGTVYSGNINLINDAFRFFTEATNWGSGLNYPYYTSVGYTIDSNLVNAMDGDSNFQFTGTPGEYFIQIDTEAKTITLSPPVVGPNCNFDQLWLVGAGTDAGWSWDNPVALPCTGNGTYSGNVTLSNDAFRFFSENTNWGSGTNYPGYQGNGYTIDPDLIDAMDGDSNFFFDGTPGTYLLTVDDINKTITLDPEQLTCEFEQLWIVGAGAVDAGWSWDTPVMLPCTGAGIYSGDVALTNDAFRFFTVNSAWDSGINYTTYEGLGYTIDSVLLNAMDNDLNFFFDGTPGTYTITVDTVGLTITVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMQ5</accession>
    <name>A0A5C6ZMQ5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Urea carboxylase-associated family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06885</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018959">
        <property type="entry name" value="DUF1989"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09347">
        <property type="entry name" value="DUF1989"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1989" evidence="1">
        <location>
            <begin position="6"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="202" mass="22467" checksum="CE40FCA018A8EEF1" modified="2019-11-13" version="1">MSTAKIIEPQTGAAFKMNKGDILTVIDPMGQQVSDMVLFNSDDQREKISAGKTMDFEECILLTEGNFLWSNRSHKMMEIIEDTNGRNDILLAPCSAETFRIMYKNPEEHPSCLTNLHQNLESYGIDMDAIPTAFNIFMNVQFSALGKLKVLPPTSKAGDLVRFKAHMDLIVGLTACSAEDSNAGTFKPIHFLVTKEQATTTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMQ7</accession>
    <name>A0A5C6ZMQ7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PQQ-dependent sugar dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_00565</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012938">
        <property type="entry name" value="Glc/Sorbosone_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011041">
        <property type="entry name" value="Quinoprot_gluc/sorb_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07995">
        <property type="entry name" value="GSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50952">
        <property type="entry name" value="SSF50952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022968532" evidence="1">
        <location>
            <begin position="23"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="domain" description="GSDH" evidence="2">
        <location>
            <begin position="41"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD91119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="370" mass="41363" checksum="FC5914317DEDCDA6" modified="2019-11-13" version="1">MNHRCTLSVLASLLLWSLLACAQDKNPINTKNSHEVVVPDLSIPWGFCFLPDGAMLITEKEGELIHFKDGKKTQISGIPEVYNRGQGGLMDIKLHPDYKDNDWIYLTYASSEGEEEGGNTALMRAKLKDNALVEQEILYKATPNTTRGQHFGSRIVFDDDGYLFFTIGERGNRDENPQDISRDGGKVYRLNDDGSIPDDNPFVNTPNAKKAIYSYGHRNQQGMVINPTTQAIWAHEHGPKGGDEINIVEAGKNYGWPVITYGVNYSGTTITDETSRPNMAQPLYYWVPSIAPSGMEFISSDVYEGWKGNLLVGSLKFQYLDNCYIKDNKVVKQERLLDGLGRVRSINQGPDGFIYVGIENLGIVKLIQTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN70</accession>
    <name>A0A5C6ZN70_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2807 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_02145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021255">
        <property type="entry name" value="DUF2807"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10988">
        <property type="entry name" value="DUF2807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2807" evidence="1">
        <location>
            <begin position="41"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="250" mass="28088" checksum="CAEC1EEC16AB9DE2" modified="2019-11-13" version="1">MRNFFYLLMPIFLLSCNGENVPNCFQNAGDLIQKEFAVEPFTQITVFERIELIITQAPEQKVTVETGEYLMNDIEVKVENGRLKLYNNNACNITRDYGLTKIFVSVPNLTEIRNSSGLAVRNEGVLNFDRLALISEDANGEDTFHTDGDFRLEVNCIDFSVVVNNLSSCYISGQTTNATIGFFSGDARFEGRNFIAQNVTIFQRSSNDMIINAQQSLKGEIRSTGDVILVNTPPIVAVEQFYTGKLIYEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNQ8</accession>
    <name>A0A5C6ZNQ8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF305 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_02730</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005183">
        <property type="entry name" value="DUF305"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03713">
        <property type="entry name" value="DUF305"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="DUF305" evidence="3">
        <location>
            <begin position="101"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="130"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD90964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="157" mass="17845" checksum="D8DA81BDCCDAB170" modified="2019-11-13" version="1">MNHDSKKQNNYTKFVGMLAASFVAMYITMYLNTYAIDHVYFSLTRFYMSCLGISAMAIIMYVAMRGMYQNKKKNIAIIVGSIALFASALGLVRAQAPIIGDVLWMKAMIPHHSIAILTSERADIQDPEVKQLAEDIIKAQKKEIEEMKQMIKRLEDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNS1</accession>
    <name>A0A5C6ZNS1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carboxyl-terminal protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_03110</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041613">
        <property type="entry name" value="Pept_S41_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18294">
        <property type="entry name" value="Pept_S41_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="PDZ" evidence="2">
        <location>
            <begin position="99"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="498" mass="55208" checksum="03969C67EEF41411" modified="2019-11-13" version="1">MKLLKHILILCTCLSLTSCFEDNDDNLISSIDINDFVWKGMNAFYLYKDEIPDLANDRFASDEGYSSYLNSFSAPEALFESLIFQRETTDRFSVIVRDYIALEQQFQGTSVSNGMEFGLFRFNASDSQIYGYVRYVLPNTSAEANNLKRGDIFYAVNGTALTIDNFRNLLLASNSYSINLGNYNDNGTPIIADDSITPTETTIALTKAAYTENPVYLHTVLDVGNETVGYLMYNGFTGTDAFDSQLNAVFSEFQSAGISDLVLDLRYNGGGSVNTAIWLSSMITGQFTGDLLVREEWNSDIQAEILANNPESLLNPFVDQMIKTNGNGEVVFQENINHLNLNKVYVLTTENTASASELVINGLNPYITVIQIGTKTRGKYQASTTLYDSPNFRRTEANPNHTYAMQPLILKSINSVGFTDFDNGLLPQIGLEENFGNLGVLGNENEPLLAAALADIQGLGRFNQTINDVSPTLEVQFEADPFENEMYVAPNDFLNGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNV8</accession>
    <name>A0A5C6ZNV8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">6,7-dimethyl-8-ribityllumazine synthase</fullName>
            <shortName evidence="7">DMRL synthase</shortName>
            <shortName evidence="7">LS</shortName>
            <shortName evidence="7">Lumazine synthase</shortName>
            <ecNumber evidence="4 7">2.5.1.78</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ribH</name>
        <name evidence="8" type="ORF">ESY86_00680</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>(2S)-2-hydroxy-3-oxobutyl phosphate + 5-amino-6-(D-ribitylamino)uracil = 6,7-dimethyl-8-(1-D-ribityl)lumazine + H(+) + 2 H2O + phosphate</text>
            <dbReference type="Rhea" id="RHEA:26152"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15934"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58201"/>
            <dbReference type="ChEBI" id="CHEBI:58830"/>
            <dbReference type="EC" id="2.5.1.78"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Cofactor biosynthesis; riboflavin biosynthesis; riboflavin from 2-hydroxy-3-oxobutyl phosphate and 5-amino-6-(D-ribitylamino)uracil: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the DMRL synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.78" evidence="4 7"/>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00275">
        <property type="reaction ID" value="UER00404"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009349">
        <property type="term" value="C:riboflavin synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000906">
        <property type="term" value="F:6,7-dimethyl-8-ribityllumazine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09209">
        <property type="entry name" value="Lumazine_synthase-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.960">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00178">
        <property type="entry name" value="Lumazine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034964">
        <property type="entry name" value="LS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002180">
        <property type="entry name" value="LS/RS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036467">
        <property type="entry name" value="LS/RS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21058">
        <property type="entry name" value="PTHR21058"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00885">
        <property type="entry name" value="DMRL_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52121">
        <property type="entry name" value="SSF52121"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00114">
        <property type="entry name" value="lumazine-synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0686">Riboflavin biosynthesis</keyword>
    <keyword evidence="6 7 8" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="5-amino-6-(D-ribitylamino)uracil binding" evidence="7">
        <location>
            <begin position="65"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="5-amino-6-(D-ribitylamino)uracil binding" evidence="7">
        <location>
            <begin position="88"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="1-deoxy-L-glycero-tetrulose 4-phosphate binding" evidence="7">
        <location>
            <begin position="93"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>5-amino-6-(D-ribitylamino)uracil</name>
            <dbReference type="ChEBI" id="CHEBI:15934"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>5-amino-6-(D-ribitylamino)uracil</name>
            <dbReference type="ChEBI" id="CHEBI:15934"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>(2S)-2-hydroxy-3-oxobutyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58830"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD91137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="161" mass="17634" checksum="5F0D40A3A9A40AB8" modified="2019-11-13" version="1">MATANHNLSNYDKSTLPNAEHFRFGIVVSEWNDTITNGLFQGAYDALIDCGANEDNIIKWNVPGSFELIYGAKKMIEHRVDAVIAIGSVIQGETKHFDFVCEGVTQGIKDLNVISDTPVIFCVLTDNTMQQSLDRSGGKLGNKGTEAAIAAIKMAHLRRTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNZ9</accession>
    <name>A0A5C6ZNZ9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="13">Ion transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">ESY86_00950</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008076">
        <property type="term" value="C:voltage-gated potassium channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005249">
        <property type="term" value="F:voltage-gated potassium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028325">
        <property type="entry name" value="VG_K_chnl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027359">
        <property type="entry name" value="Volt_channel_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11537">
        <property type="entry name" value="PTHR11537"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0407">Ion channel</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0630">Potassium</keyword>
    <keyword evidence="5" id="KW-0631">Potassium channel</keyword>
    <keyword evidence="3" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="92"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="154"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="Ion_trans" evidence="12">
        <location>
            <begin position="27"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TXD91187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="293" mass="32784" checksum="1BE15AD8D3C4E11A" modified="2019-11-13" version="1">MNKNKPNKTWRSKLHEVIYEADTPAGKTFDVILLVAILASLAFVMLESVSHIDAKYHEFLFVAEWVITILFSIEYIARIITVKQPLRYIFSFYGIIDLLSTIPMYLSFFIAGSHALIALRSLRLLRVFRVLKLARYLGASNMLSMSLKASRAKIFVFLFAVLILSIIFGTLMYLIEGADSGFTSIPVSVYWCIVTLTTVGFGDIAPVTPIGQFIAAIIMIMGYGIIAVPTGIVSAEYSAQNKKDGKAEEQADHKSKPAEIQMNSQSCFNCNATEHKDKAEYCYKCGHRLHPNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6Z956</accession>
    <name>A0A5C6Z956_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF4886 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_20560</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000087">
        <property type="protein sequence ID" value="TXD86171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="106" mass="12229" checksum="376704EB61339A51" modified="2019-11-13" version="1" fragment="single">SIEKDKCCSPVLENLEQEFNVINESYNLVAKENDLIESNNGTKYFEVRTKFPEIELYEDESHPNENGAFLNACIFYQMLTDKKASDLIYNGEIEPKTAEKLKKIAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAC7</accession>
    <name>A0A5C6ZAC7_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NAD(P)-bd_dom domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000089">
        <property type="protein sequence ID" value="TXD86143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="5"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="127" mass="14353" checksum="8D8009EE80D3DE2C" modified="2019-11-13" version="1">MLTFKIVENRKEKNIKRIISLSGGGLPFPEKDKPKFADKLIRTIMKIVVPKILNDAIKHHEILKSSGLNWTIVRGPRLTNDAKTGTYRVGWVGVNAGMKVSRADLADFILSQVDDEKFNFQMPFVSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAQ1</accession>
    <name>A0A5C6ZAQ1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">N-acetylmuramoyl-L-alanine amidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_19895</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000051">
        <property type="protein sequence ID" value="TXD86571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008745">
        <property type="term" value="F:N-acetylmuramoyl-L-alanine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02696">
        <property type="entry name" value="MurNAc-LAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002508">
        <property type="entry name" value="MurNAc-LAA_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01520">
        <property type="entry name" value="Amidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00646">
        <property type="entry name" value="Ami_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022731782" evidence="1">
        <location>
            <begin position="23"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="MurNAc-LAA" evidence="2">
        <location>
            <begin position="92"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="209" mass="23325" checksum="5877A5AFA8508A2E" modified="2019-11-13" version="1">MKKVLKNVSFVFLLLKMCIIFGQETSAQKRIIIDVGHGGKDSGAIGVNDIQEKDVVLGIANAILRLNNELEKPLNIYLTRYSDTLISLSDRTKLAKILKADLFVSLHCNHSDNPDARGVEVYASKKQGKYSRQSVFIGFQIEKALCKTIGYESRGVKFGDFQVIRETVNYCPSLLLELSFLSNRDEGSYISDALNIQFIASTILLSIQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAT9</accession>
    <name>A0A5C6ZAT9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19175</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000037">
        <property type="protein sequence ID" value="TXD86816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="227" mass="26039" checksum="62E72B6D4B3D9233" modified="2019-11-13" version="1">MYSTVTKYAEVTDITVSSYPESESINNAIKEAAATLEVNAGRYNDEIVTSRLWTSFTFPSTSKELFSESFATMQQDKNPEFENYERLIFDASQYLFSNPVNPNGTEFKAAAQIVGFWMNRDTGMNIPTFGDFFSVLTNKNQQQFLYTIAMINYGLDQKINHNRILKCEKIEGQKYSELDDVREVQLGGAKVLLEFIGNQKNNVPMTTKTKTYYKAYKKKKLGEELFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAY7</accession>
    <name>A0A5C6ZAY7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_18110</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000029">
        <property type="protein sequence ID" value="TXD87143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022964200" evidence="4">
        <location>
            <begin position="16"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="717"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="5">
        <location>
            <begin position="863"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="762"/>
            <end position="796"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD87143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="924" mass="104631" checksum="3E5ADC269270B495" modified="2019-11-13" version="1">MFCLCALLLSTKAYAQYTPYFQNFDLSEYNAGNQNWGVSKAKDGKLYVANNKGLLEYDGLNWKLFTIPNKTTLRSVLAKDNKIYIGSYEEFGYFETDAKGKLNYTSLSQMLDGEQFLNEEFWQILAFEDTIIFRSFRNIYVYKAGKITKIRPSSTVISCEVVDGEVYVATLKDGIYKLEGSALVPFLDNAVLDGAKVVSIIKYAEGLLIATDLSGNFLYNGSSLKAWNAPINAILKKYQLNALSTQKSGNLVFGTIQNGIYITNSDGSIVFHINHENGLINNTILSQYIDEDNQLWVGLDNGLAHVDLKSKSAFFNDVTGKLGAVYDVIDYKGRIYIGSNTGLYYLSSDGKLIFIENSQGQVWSLKIVDGDLLCGHNNGTYLVEGDQIELISAFTGGWVIKKVPEINDTYIQGTYSGLVRLKKVKGEWEAKHLGKTTIPIRFLVFEDASTAWAAHAYKGLFKVKFSNTYDTITSIQNYENKGLSSTYNVRVHKIKNTICIKTNTGWQRYEPILDSIVPHDLLNKNFGKNSYIISDDEVNVLALKRGDLIHLKPFDTENSSTTLESSHIKDRLIVGYENVSQLDNTHFGLNLNDGFMRIDKNLPRSVYQVYKPSIDGISVNGAPIAIPNDTPIEIPNKNQSLLIELSSPKSHAHAFQYALTNVDPNHWYKIENGALELSNLGQGEYALAFRTVNESGTTSESTRLYITILPAWYRSNLGLLGFTLLAFLLILLFYVLHKRKILKEQLILKHQFEKDQEILLKDKTIENDKRIVELKNESLENELELKSKQLANTAMAIVKKNETLLELKDELLDHKSAFDNYYAYKKLIKKIDTSIGHEDEWAIFEHNSNQVHEAFFKQLVEKHPDLTPKDLKVCAYIKMDLSTKEIAPLLNISVRGVETQRYRLKQKLQLESEISLTDYLLNFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZB15</accession>
    <name>A0A5C6ZB15_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Conjugative transposon protein TraM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">traM</name>
        <name evidence="2" type="ORF">ESY86_17860</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000028">
        <property type="protein sequence ID" value="TXD87180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022187">
        <property type="entry name" value="Conjug_transposon_TraM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12508">
        <property type="entry name" value="Transposon_TraM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="304" mass="34515" checksum="175AFB5BFCD366C8" modified="2019-11-13" version="1">MKIEKNKIVFGSVMGVILIFLVSYTFMVMGDDESEDESLKQTLVPALEENQKIYDSKLDAINDLKEVRQANAPSIYDEKLMDSLGFYDADYTEKEKKRIVDSIYSSGRISYSETPSENSVSRKPRLIPDEKVDMEPVLEIKELGFEHQLFFSSAPKENKLISVGSTDDIIYVTVDGTQIVKTNSRLRMRLTKEAIINNILVEKNTSVYGFVNFQPNRATIEIENIQHQPTHLKAFDLQDGSEGLYVENNFRAEATNEVVDGVIQDINIPSVPQIGGITRVLKRNNRNIKVTILNNYKLILKPTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZB23</accession>
    <name>A0A5C6ZB23_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_17910</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000028">
        <property type="protein sequence ID" value="TXD87190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="3"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="219" mass="25707" checksum="012906C6010D41BF" modified="2019-11-13" version="1">MSKIAIIDDDKSQRETLKSILKSHLYNLESNLEVIDTFPFPDDLIYEYNEWIEQNEIVCLIFDEQMHNDSEENSEPVGYRGNQLVMEIRKTYKDIPIYVITSHKNDDDLQAKFSEFEDIIGREEFILDGEKYVKRFLRASQGFLEEHISELSELKELSELVASGKSSDEDLVKLKALQLKLNITLDSSLGERKDWLDDYESKIQFLEKLQKKIENKITE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBK1</accession>
    <name>A0A5C6ZBK1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000029">
        <property type="protein sequence ID" value="TXD87129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023031224" evidence="1">
        <location>
            <begin position="23"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="529" mass="61393" checksum="78AF81CCAD032F43" modified="2019-11-13" version="1">MKVYNQLILYLFFLIASIQLNAQDASQVFKNDSITLAQAYINLSLTKDYFDKLSDERLSKILPFETDELKSIKDSIFISENSTLFNFTYSLLYFNEAKLLFRSKSKTLERDILIQWHDHLKKAIAHYNLSNYFTNGENVFYQLINFDEKLYDELRWNINALKKEFTPYFNTDIYPDFKRLFYKAKRSKTYDFDKLTYFASLYDLSLDLSIIETEPSYEGFNFNSIAQNYQLDLKLDLIARYLQLKYMASNQYTKELSPTEILRLYKAYDSFYYDIVDNKNQFEEDAFITKELNPEVCDALYKELQKKFALDDITDTDLDGVIDASVGQNIAAPRQYFFPNPAPLPSASATFKNFKPELVTLGKVDTYISNLFTSAGYKNRLHYYYDLDGFAMTTSLEKFNKDGSAIEDSKRWVKNLGGDGKFSYYEIFKSLFFEIESEFRMFAIIIASEEVRISSVALTPGGAETLLKNSHPALPDALKNKTLPNKNLTVLVYHFHQNDVGQVPMLDLSGNVKVQDHLKKAGLSKLIRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBR9</accession>
    <name>A0A5C6ZBR9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF1801 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18805</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000034">
        <property type="protein sequence ID" value="TXD86920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014922">
        <property type="entry name" value="DUF1801"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08818">
        <property type="entry name" value="DUF1801"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1801" evidence="1">
        <location>
            <begin position="20"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="151" mass="17349" checksum="EF45BCB2E2F5E5F0" modified="2019-11-13" version="1">MKKQIPTAAAYIDQLPEDRKTAVTNIRQCILEHLPKGMTEVMSHGMLSYVVPHSIYQKGYHCDPKSALPFMGLASQKNYIALHHMGLYANKELLDWFVAAYTQHSKYKPDIGKSCIRFKRMDDIPLQLIGELCSKINTLQWIETYESAFIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC96</accession>
    <name>A0A5C6ZC96_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_18030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000029">
        <property type="protein sequence ID" value="TXD87127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="568" mass="65204" checksum="408014DF47B9FC2C" modified="2019-11-13" version="1">MKTIRIFIASSSELKDDRDQFRKFISMENDRLHTKGVYLEIVQWENFLDAISDTRLQDEYNNAISNCDIVLCLFFTKVGKYSSEEFDTAYQVFKDKGKPKIWTYFKDAQINTGSITDEINTLLAFKKKIGSLGHFYTKYTNIDNLINQYRSQLDKYLPAFETNFGAQKELPHNADAPQPAEKPIENTFNDVLTKSLIQAIKPYDRKANDFLSTYADWEKNKDLVPTVKRIIISGYVGVLGMQLRKLMSIGEEDFSDYKMKRYLENCHLTALRALQLICYALISSLWDNHLKNKLKLSNDQNSVLIKFFKNATDESIKGLTALSKTLITVFLDNQLEFPIAELKDFLPKLQAGNDLSTACADLNTVAELLDGTSYTLVDCANAEKNLAILLESLNFLVAYKMISIKDIDYSFQRNDKEGFYLHHYTLLDGDSQASTNKYGKIRKDSTPVTSYAVLLFKDNYQKNINLVPFVIDYNGLADAGGSKICFYSFCNTFDDMNLNYNFIEDNSKVTIKKSGNMKPDDTDVRAINNWLSDKENRKDMNFDNVFDLFYKAKKALVGIEEDTEMDEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCE4</accession>
    <name>A0A5C6ZCE4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TraG family conjugative transposon ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">traG</name>
        <name evidence="2" type="ORF">ESY86_17880</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000028">
        <property type="protein sequence ID" value="TXD87184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022509">
        <property type="entry name" value="Conjugation_ATPase_TraG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043964">
        <property type="entry name" value="P-loop_TraG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19044">
        <property type="entry name" value="P-loop_TraG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03783">
        <property type="entry name" value="Bac_Flav_CT_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="P-loop_TraG" evidence="1">
        <location>
            <begin position="396"/>
            <end position="797"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF19044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="799" mass="92284" checksum="2CFAFD36621A4A90" modified="2019-11-13" version="1">MNKINLSAYQPIADIQDNILFANNGNVILCYEGNLPEIYSLSEKDFEDMHGAWFQALKSLPVGTVVHKQDIYLKKSYSSEQLPNKTFLEKATHEHFKGRDHIEHKCYLFFILTKNKSLNNPKYINPFRKVSKGIIQELDDNIKSFANSVSDSVSFINNSRKMAFLPLIAEQIQQLTNGYFNGFNEGFDTDIILDKKSVTIGENHFDALAINSELCFGESVQSSKTNEKFTSDDFVFHQGFIDGLGLTLNENHIVNQIIYLDDKQKWRKLLDKKIEELNKSSNFGSQNKVVLEKIQHILDQINADDNARIIRGHLNIVYWAKEAKELDKITSKIKTEFKELDIIPYYPRGEERKNYILNSYCCFSSNFSNNDLYVTDLKHALCLFINNTNYKSDTTGIIFNDREHNIPVLKDVWDERKKRIKARNFAIFAPTGEGKSFLANNILRQYFESGVRLVIIDLGGSYTKFAKLYPEQYTVLRYESGKNLGINPFYISNQNDLTPERLEDLSVFLFELFASDLEVTKAQSVSVKKILRCYYDSTSENHSLEGFYNFIETNQDDLLDNLKIHPDYFNVTSFLHVMSEYVGDGLYSFLFEVSEDQTYKIEDKRLIVFELDEVKDNKEILSVMLKLIKSAIQRTIWKNRAEKGIILFDEFAKQLKFENVLESVEFYYQAIRKQNGAIGIILQSINQLPNNSTSASILENTQVIYSLNNEKGYDELVKRLNLSSHDLNQLKSIKNNLSGPRKYTEMFIKIGRESNVFRLEVPKEVYAAYLTDGKENDAIMAIYKKTGSMEEAIKIFINS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCI0</accession>
    <name>A0A5C6ZCI0_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidase S74 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_15620</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008640">
        <property type="entry name" value="Adhesin_Head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030392">
        <property type="entry name" value="S74_ICA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13884">
        <property type="entry name" value="Peptidase_S74"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05658">
        <property type="entry name" value="YadA_head"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101967">
        <property type="entry name" value="SSF101967"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51688">
        <property type="entry name" value="ICA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022814380" description="Peptidase S74 domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase S74" evidence="3">
        <location>
            <begin position="528"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD87741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="651" mass="71313" checksum="47826D6C9C6FE770" modified="2019-11-13" version="1">MKIRHLILLALLPLFSVNAQNFEDNFANESINDVPTQWRNVKGLGRIGELDGQKVLNLDRYTVVSPIVNGQDNNYLGDQFTIEFDAFFYDASSPNRQYYIIHLWEGTGVYGENGKHTDPYLIYKHGITVTGSFVNRKKLEPLAELERKWRHIKIEFAQKTLKIYINSRLTHIQPDLFYDPPMVSFSARNASGATSGITNVTITDQVDSIGPTTDEEPDDNSTSDQNLPYTFPPNDGNANQILQTDGQGTLSWVDFLADSSAGDSSTGLEAIDQGNGIGWRLVNGNEEYYGNIGKNAIDLSIESRSNRKNNEKGAMGEHAFASGNSTTASGRFSTAMGQNTIASGTNSMTMNSNTTASGLSSTAMGNSTWASGTNSIVAGNNTRAFGDNSVAMGGGVIADANNSFAIGRYNIGGGHPKEWREIDPIFEIGNGKSYPDKGTKEKSNALTVLKNGNIGIGTHTPQVKLHIQDGLDANNSKGGYLIIGDKQKENIVFDNNEIIARNNVQPAILYLQSDGGDVYVGRAVVHSSDRRLKQDIENLNYGLNEILQLRPVSYHWKSNPDATNKSLGLIAQDVQPILKELITANTNNGNDTLGVNYTELIPILIKAIQEQQTVIENLKSSATHKDEALVQLNERIEKLETLYSTHKISQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCI5</accession>
    <name>A0A5C6ZCI5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000036">
        <property type="protein sequence ID" value="TXD86855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="60" mass="6400" checksum="4531AAC4C7BDCD54" modified="2019-11-13" version="1">MNKSKIGIVMSIVGLFIIGLSIGYGLANGETNLGFTFAGVFVVFIGVFVLLFSNKKKLNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCZ8</accession>
    <name>A0A5C6ZCZ8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Orotidine 5'-phosphate decarboxylase</fullName>
            <ecNumber evidence="4">4.1.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">OMP decarboxylase</fullName>
            <shortName evidence="4">OMPDCase</shortName>
            <shortName evidence="4">OMPdecase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">pyrF</name>
        <name evidence="6" type="ORF">ESY86_16620</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>H(+) + orotidine 5'-phosphate = CO2 + UMP</text>
            <dbReference type="Rhea" id="RHEA:11596"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57538"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="EC" id="4.1.1.23"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 4">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the OMP decarboxylase family. Type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.23" evidence="4"/>
    <dbReference type="EMBL" id="VORO01000023">
        <property type="protein sequence ID" value="TXD87517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004590">
        <property type="term" value="F:orotidine-5'-phosphate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01215">
        <property type="entry name" value="OMPdecase_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011995">
        <property type="entry name" value="OMPdecase_type-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001754">
        <property type="entry name" value="OMPdeCOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43375">
        <property type="entry name" value="PTHR43375"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00215">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00934">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02127">
        <property type="entry name" value="pyrF_sub2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="3 4 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OMPdecase" evidence="5">
        <location>
            <begin position="16"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD87517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="270" mass="29821" checksum="68875B50ACA9D3B7" modified="2019-11-13" version="1">MTTQELIAQIKKKKSFLCIGLDVDLEKIPKHLLNDEDPIFAFNKAIIDATHNLCVAYKPNTAFYEAYGLKGWRALEKTVNYLNEKHPEIFTIADAKRGDIGNTSTRYAKAFFEDLGFDSVTVAPYMGRDSVEPFLAFENKHTILLALTSNEGAFDFQTKLVDGKSLYNQVLETSKAWKNAKNLMYVVGATKAEYFKDIRKIIPDAFLLVPGVGAQGGNLQDVCKYGLNAQIGLLVNSSRGIIYASEGVDFAQAAATKAEALQQEMAAILS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD09</accession>
    <name>A0A5C6ZD09_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">T9SS type A sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_16670</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000023">
        <property type="protein sequence ID" value="TXD87527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038081">
        <property type="entry name" value="CalX-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007346">
        <property type="entry name" value="Endonuclease-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044925">
        <property type="entry name" value="His-Me_finger_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33607">
        <property type="entry name" value="PTHR33607"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04231">
        <property type="entry name" value="Endonuclease_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141072">
        <property type="entry name" value="SSF141072"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54060">
        <property type="entry name" value="SSF54060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022709375" evidence="1">
        <location>
            <begin position="20"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="domain" description="Por_Secre_tail" evidence="2">
        <location>
            <begin position="591"/>
            <end position="658"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="659" mass="73179" checksum="1B545604637B04C6" modified="2019-11-13" version="1">MKQLLLIVSALIFMPYSFAQVVINELDCDTPSTDDREFVELLTATPEAALDGYVLVFFNGSNSGGNSSYFALDLDGYVSDVNGLLLIGSNDVSPVPQVLISANTIQNGPDAVAIYQADDLDFPEFTVATIDNLIDVLLYDTSDPDDQDMIAIFSADPRFTSIEQINEGPGNNTNSIQRFEDASGNVTYTSTVPTPRQLNDGSGIVLNGIRIDLEQRQYDEDASFNITFTSETPVVETLDFNILFDNDTFDTNDFTGNTSLSIPMGTTSTMTSINLIDDALDEGDEVTRLRFESLPSGYLALNNNIAIRIVDNDYTASGFGTPVNPTFGNVSSTQPSGYYNSLDALGDTNLRQALQDIIADPSIVREQSYADVIDILKEADQNPEHSNQVWLVYTEQGRPKLDFQVNNQITGKWNREHTFPRSRGGFFSIEEDEIADGKDLFWTTSADSLRHGNSDAHALRAADGIENSTRNNQFYGQYTGPAGTQGSFYGDVARSVFYMAIRYNGLEVVNGYPEGNLGQMGDLATLLDWHRNDPPDDFEMNRNNLIQTWQFNRNPFIDQPDLVEYIWGNNTGDLWSQALGVTDFNANNIFIYPNPAGNSIYVKGLVAETTIAVFSMEGRKIKTFRRDANCKLDLDLPPGIYLLHFYSENKQRVKKLVIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD66</accession>
    <name>A0A5C6ZD66_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022971855" evidence="1">
        <location>
            <begin position="20"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="164" mass="18012" checksum="B398024F6EBC6F42" modified="2019-11-13" version="1">MKKITLALIAIISISFVNAQAFKGQGDQKFQVAANIQDEATGVNISYDYGLGQNISVGFSSSYALGVSDFLDADFGDRFDLKARFNANLGNVINIDENFDFYPGLSLSLKNFGGHVGARYFFTEGFGIFTEANFPLAKYDENKLDPANYIHNQFTLNIGASFNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD88</accession>
    <name>A0A5C6ZD88_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_18335</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000031">
        <property type="protein sequence ID" value="TXD87018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="161" mass="18105" checksum="80868343E350ACD3" modified="2019-11-13" version="1">MTKTYPYDITFKVQMTDKKGSEIIDNGIIPWISIDDPKLEIVNLHDRDEIVISENKVVFVIEYPLTKPAEINIDAKTNLGFTRAELVSAVSAAYHRIYKEELETSIIKTIPVEEREGTVNRNETNGSYGIWGHDIGDLVLVAVEARKTESGELKLELIVAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDB1</accession>
    <name>A0A5C6ZDB1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_16580</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000023">
        <property type="protein sequence ID" value="TXD87510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="131" mass="15399" checksum="CC9273FAB8E517CD" modified="2019-11-13" version="1">MYYNLPSHLSDLPIYRKAMDILMLSRNISTYLSQDLSYLNPDGSEDAHIYFSGDIIQQSESLVPEIEKAQAGRYSEKKDQHLASIERLTQRLHINCNRLERCNSNGSEYLPILRSELRKFRKLQRHWVLTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDQ2</accession>
    <name>A0A5C6ZDQ2_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Sodium/proline symporter</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Proline permease</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_15470</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the sodium-dependent uptake of extracellular L-proline.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>L-proline(in) + Na(+)(in) = L-proline(out) + Na(+)(out)</text>
            <dbReference type="Rhea" id="RHEA:28967"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005298">
        <property type="term" value="F:proline:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031402">
        <property type="term" value="F:sodium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015824">
        <property type="term" value="P:proline transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd11475">
        <property type="entry name" value="SLC5sbd_PutP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1730.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038377">
        <property type="entry name" value="Na/Glc_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011851">
        <property type="entry name" value="Na/Pro_symporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001734">
        <property type="entry name" value="Na/solute_symporter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00474">
        <property type="entry name" value="SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00813">
        <property type="entry name" value="sss"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50283">
        <property type="entry name" value="NA_SOLUT_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0915">Sodium</keyword>
    <keyword evidence="8" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="8" id="KW-0769">Symport</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="120"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="158"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="188"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="232"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="273"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="327"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="376"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="405"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="436"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="470"/>
            <end position="489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD87867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="497" mass="54578" checksum="ADFE7F8EEFE64296" modified="2019-11-13" version="1">MITKLIVLSVYVAILFLIGILASRRVKSMSDYYLGGKKMGFWAVAFSARATGESGWLLIGLTGMGAIAGYSGYWVVVGEVLGVFLSWQFMAKKFKRRSDDYNSITIPDYLQSHFKSSTNTLRILSASVLVVFVVIYVASQMDVTGIAFESMLNIDYRIGALVGFGIVLLYIFVGGFVAAVWSDMFQGILMFFGLVLIPIVVWFSMDHGAGVTAGLNAIDPTLTQIMGRSEDGWMNFFTILGFSMIGLGFLGSPQVYVRFMSIKSEKEIDKGKWVALIFTLLTDAAAVTIGILARIYFTKEGQDPEAILGTGGEDVLSMITHEFLPTILVAIFIAIVLSAIMSTIDSLLILASSAITRDFYQKIFRPDLKDKDLTKLSRLVTVAMAMAALGIAILLYNLYPDRQVFWIMIFGWSGIAATFCPVIILSLFWKGYSEQGAIVSMITGFASVILFKFVFAKIEGIGAYLQELDVLAPSFALAMITGYIASKIYPPKHDGIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDT3</accession>
    <name>A0A5C6ZDT3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SPOR domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_14345</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042834">
        <property type="term" value="F:peptidoglycan binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1070">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007730">
        <property type="entry name" value="SPOR-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036680">
        <property type="entry name" value="SPOR-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05036">
        <property type="entry name" value="SPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110997">
        <property type="entry name" value="SSF110997"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51724">
        <property type="entry name" value="SPOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022946791" evidence="1">
        <location>
            <begin position="25"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="SPOR" evidence="2">
        <location>
            <begin position="46"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="126" mass="14626" checksum="607DE52FCE8BCDE0" modified="2019-11-13" version="1">MIYNKFKISLLALTFFAFLGNALAQQGNVTVDQHSDITKLLEYKKDVKTVNLYKIQLDFGSRAEAESLKIEFQNEFSEWPAEMVYETPNYKVWVGNFSTRLEADIALQKIKKSFTKAMVFEPKKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDU9</accession>
    <name>A0A5C6ZDU9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3 4">Single-stranded DNA-binding protein</fullName>
            <shortName evidence="2">SSB</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_19015</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000036">
        <property type="protein sequence ID" value="TXD86848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04496">
        <property type="entry name" value="SSB_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00984">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000424">
        <property type="entry name" value="Primosome_PriB/ssb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011344">
        <property type="entry name" value="ssDNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10302">
        <property type="entry name" value="PTHR10302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00436">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002070">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00621">
        <property type="entry name" value="ssb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50935">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR002070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD86848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="111" mass="12530" checksum="C12386D8FFC6D78B" modified="2019-11-13" version="1">MSRLRNKVQLIGILGKDPEIMKLESGKTLSKFSIATNESYKNAKGELVKDTQWHHVLAWGKTAEVIEKYVTKGKEIAIEGKLTSRAYDDKEGVKRYITEVVCNEMLMLGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE02</accession>
    <name>A0A5C6ZE02_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">OmpA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_15050</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022740451" evidence="2">
        <location>
            <begin position="22"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="OmpA-like" evidence="3">
        <location>
            <begin position="146"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD87985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="287" mass="31784" checksum="0C4402CCCB4BACA2" modified="2019-11-13" version="1">MKKLMLLSVVGMLIMSSCVSKKEFTALEAKQKETQDLLNTATVKLNSCLTDKAASDARVSGLQDQLADMRSTNLDLINTKGNLTTLTQKGAENLEKSLESLKERDLKITRLQDALTRKDSVTLAIVSSLKRDVGLNDPDIQINVEKGVVYISIADKLLFQSGSYNVTSRAREILAKVAKVVNSKPDFEAMVEGHTDSVPYNKGGVLVDNWDLSVKRATSIVRVLEDLGVNPKQLVAAGRSEYVPLVPNDSVENRATNRRTRILVLPKIDQFYEMVEKEMKNLAESEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE58</accession>
    <name>A0A5C6ZE58_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_13505</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="103" mass="11612" checksum="35B69C20D2F883C3" modified="2019-11-13" version="1">MSIHIVNIFVLMCIHKLKVNQPFLILEVQALFEIKKNDFEDKVKQDDGSYLVAKGPAFHFALLAVGSARGILHTKTEGTAYSGYLLPTIDVKQLVEQDVVFRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE91</accession>
    <name>A0A5C6ZE91_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Efflux RND transporter periplasmic adaptor subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_14570</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="3">
        <location>
            <begin position="52"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="386" mass="41975" checksum="F461D17E2EC4ECBA" modified="2019-11-13" version="1">MKRTKTAILLISIVVVFAAALIYLWKKNQEDPVTYTTESPTMETITVKTVATGNIVPKEEILIKPNISGVIEKVFIDAGQYVKSGDLIAQIQVIPNVSSLTSAKNNIASNRTSLETAKINLQTQQANYDRQKALFDKGVISANDFEGVRNTYLQTKQAVEQAKINVNSATQNYDIIKTGTTSGVGNSAQTQVRATVSGMVLDVPVKAGNQVIEANNFNEGTSIASLADVKQMIFEGKVDESEVGKIKEGLPLEITVGAIENQKFEAVLDYIAPKGVAENGAIQFEIKGSIKNIDSTFIRAGLSANASIILDKAENVLAIKEALVQYDQETKKPFVEIAVGDQEFERRDVELGISDGIFVEVKSGISKDDKIKVWNQVQGIPTYAQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEH0</accession>
    <name>A0A5C6ZEH0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Calcium/sodium antiporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_16645</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000023">
        <property type="protein sequence ID" value="TXD87522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004481">
        <property type="entry name" value="K/Na/Ca-exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10846">
        <property type="entry name" value="PTHR10846"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00367">
        <property type="entry name" value="TIGR00367"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="76"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="101"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="129"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="158"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="201"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="237"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="269"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="292"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="Na_Ca_ex" evidence="6">
        <location>
            <begin position="2"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="Na_Ca_ex" evidence="6">
        <location>
            <begin position="170"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD87522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="313" mass="32986" checksum="E37A15A53F8C0584" modified="2019-11-13" version="1">MSILLLVLGLILLVIGGEFLVRASVALSFKMNISKMVIGMTVVSFATSAPELLVSLNAALTGSPAIALNNVIGSNIANIGLVLGITAIVSAIGVDKSFYKINWPAMMLFSIALYYFLYNDNELSRIEGGILFLGLIAFMIFLIKVARKDVETDEVDDSLAVVSSFKIATWLLIGAAALYFGSVWLVDGAKELAISLGVSDAVIAATVIAIGTSVPELAASVIAAVKKEKALSLGNLIGSNIFNIGSVLGLTSIIKAIPVTDPSILNSDILWMLGFSAVLIPLIVIPKKFEIGRLKGILLVACYAAFLFLAFKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEJ0</accession>
    <name>A0A5C6ZEJ0_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">50S ribosomal protein L1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rplA</name>
        <name evidence="10" type="ORF">ESY86_16305</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.</text>
    </comment>
    <comment type="function">
        <text evidence="8">Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 9">Belongs to the universal ribosomal protein uL1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00403">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01318_B">
        <property type="entry name" value="Ribosomal_L1_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005878">
        <property type="entry name" value="Ribosom_L1_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002143">
        <property type="entry name" value="Ribosomal_L1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023674">
        <property type="entry name" value="Ribosomal_L1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028364">
        <property type="entry name" value="Ribosomal_L1/biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016095">
        <property type="entry name" value="Ribosomal_L1_3-a/b-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023673">
        <property type="entry name" value="Ribosomal_L1_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00687">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002155">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56808">
        <property type="entry name" value="SSF56808"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01169">
        <property type="entry name" value="rplA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01199">
        <property type="entry name" value="RIBOSOMAL_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0678">Repressor</keyword>
    <keyword evidence="7 8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6 8 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 8" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="4 8" id="KW-0810">Translation regulation</keyword>
    <keyword evidence="8" id="KW-0820">tRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD87594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="228" mass="24668" checksum="0A91A5B2BD404C65" modified="2019-11-13" version="1">MAITKKQKESRAKVEKNKLYTLDEATTLLKDITYTKFDASVDLAVRLGVDPRKANQMVRGVVSLPHGTGKDMKVLALVTPDKEEEAKAAGADYVGLDEYLEKIKNGWTDVDVIVTMPAIMGKLGPLGRILGPRGLMPNPKTGTVTMDVAKAVAEVKAGKIDFKVDKTGIVHAPIGKASFTADKLKENAMELLTTLNKMKPTASKGIYMRSIYMSSTMSPSIAVDPKLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEJ5</accession>
    <name>A0A5C6ZEJ5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_13120</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="118" mass="13905" checksum="D68A7A812194BEE9" modified="2019-11-13" version="1">MARDEQLKERWELVVHKLSAKFADGDPLDLDAIIYLIGVQELGQLDRKFKKDHKLDLMHIAICKLLMPYGYYEFDYVDEEGWPHYIVKEELPPLKAGEQSILMKDAIVNYFLETDFIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEN1</accession>
    <name>A0A5C6ZEN1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphatase PAP2 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_12180</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxi_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="SSF48317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="acidPPc" evidence="2">
        <location>
            <begin position="60"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="190" mass="21965" checksum="837A081653C81CAD" modified="2019-11-13" version="1">MIDQIIQYDQDLFLYLNGLGNVYWDAFWLAYTAKFYWIPAYAILAYLLFKQLSLKAFFLLLVVVALMITFTDQITNVFKHGFERFRPCHEPGVMEVMRLVRDGCGGRFGFFSGHASNTMALAIFIGATLHSKYKFLIYVMVVWALGMGYSRIYVGAHYPMDILCGAIFGAFSGTLFFQLQRFLQKRFQLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEP6</accession>
    <name>A0A5C6ZEP6_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transcription termination/antitermination protein NusA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">nusA</name>
        <name evidence="8" type="ORF">ESY86_14335</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Participates in both transcription termination and antitermination.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Monomer. Binds directly to the core enzyme of the DNA-dependent RNA polymerase and to nascent RNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the NusA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1480.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00945_B">
        <property type="entry name" value="NusA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025249">
        <property type="entry name" value="KH_dom_NusA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030842">
        <property type="entry name" value="NusA_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036555">
        <property type="entry name" value="NusA_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013735">
        <property type="entry name" value="TF_NusA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010213">
        <property type="entry name" value="Tscrpt_termination_fac_NusA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22648">
        <property type="entry name" value="PTHR22648"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13184">
        <property type="entry name" value="KH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08529">
        <property type="entry name" value="NusA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69705">
        <property type="entry name" value="SSF69705"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01953">
        <property type="entry name" value="NusA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="6" id="KW-0889">Transcription antitermination</keyword>
    <keyword evidence="4 6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1 6" id="KW-0806">Transcription termination</keyword>
    <feature type="domain" description="KH" evidence="7">
        <location>
            <begin position="233"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="KH" evidence="7">
        <location>
            <begin position="307"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD88062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="410" mass="46892" checksum="28F947C579BC6136" modified="2019-11-13" version="1">MENIALIDSFSEFKDDKLIDRVTLMAILEDVLRNALKKKYGDDDNFDIIINPDKGDLEIWRNRIVVADDEVEEPNQEISLSEAQKIEPDFEVGEDVAEEVKLIDLGRRSILALRQNLISKIHEHDNTNIYKHFKELEGEIYSAEVHHIRHRAIILLDDEGNEIILPKDRQIPSDFFRKGENVRGIIESVELKGNKPSIIMSRTSPVFLEKLFEQEIPEVFDGLITIKHVVRIPGEKAKVAVDSYDDRIDPVGACVGMKGSRIHGIVRELGNENIDVINYTNNLQLFITRALSPARVTSVKINEETKRAEVVLKPEEVSKAIGRGGHNIRLAGKLTGYEIDVFREGAEEDVELKEFSDEIEDWVIEEFKKAGLDTAKSVLEQEIEDLVKRTDLEEETIKDVMRILKEEFEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF18</accession>
    <name>A0A5C6ZF18_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type IX secretion system outer membrane channel protein PorV</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">porV</name>
        <name evidence="3" type="ORF">ESY86_12610</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045741">
        <property type="entry name" value="PorV"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19572">
        <property type="entry name" value="PorV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022848201" evidence="1">
        <location>
            <begin position="20"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="domain" description="PorV" evidence="2">
        <location>
            <begin position="31"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="412" mass="45584" checksum="1DCE5758B75EC594" modified="2019-11-13" version="1">MKKYILPLILLTIYSTSNAQQEGQTITFPNQSSVITTAVPFMLIAPDARSAGMGDMGVATSVDAYSQQWNSAKYAFSEAKSGIAVSYTPYLSKLVNDISVGYLTYFNRINEQSAFGFSFKYFGLGEIEIRPDEFSQPTIEKPNEFTVDVSYSLRLAQQFSMAVALRYLRSDLRIQAVDANAQAAGSFGVDISGFYQSEEQAYDSFNGRTRLGFAIQNLGPKIKYDDGGRENFLPTNLRLGGGFDFIFDEYNKLAVTAEVTKLLVPTPPLFGFVDTNGDGAQTNDDPATPDINEAEQTIITQGQSTDVSFLSGVFQSFGDAPGGFSEELKEFTWALGAEYLYQDSFAFRAGYFNESDDKGARKFFALGAGFKYTTINIDLSYLFSASQIQSPLENTLRFSLSFNFGEGEYREY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF52</accession>
    <name>A0A5C6ZF52_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Putative mRNA interferase YoeB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_15265</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the YoeB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009614">
        <property type="entry name" value="YoeB_toxin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38039">
        <property type="entry name" value="PTHR38039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06769">
        <property type="entry name" value="YoeB_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143011">
        <property type="entry name" value="SSF143011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02116">
        <property type="entry name" value="toxin_Txe_YoeB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00030388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD87832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="91" mass="10649" checksum="E928DA419C07A442" modified="2019-11-13" version="1">MNADVTPNGWEDFYFWLDIDPPTALKIRELIKSIKQNPFKGIGKPEPLKHRLKGFWSRRITGEHRLVHRVSGTKGADQKCSIIQCRFHYDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFB9</accession>
    <name>A0A5C6ZFB9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase family 4 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_16785</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000024">
        <property type="protein sequence ID" value="TXD87435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="162"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="338" mass="37283" checksum="26F8881C235B5DE2" modified="2019-11-13" version="1">MKNLLYLGNNLNRANANVSVMGTLGPLLEQEGFGLIYASSKSNKVLRLWDMVWTLISKRKHVDLILIDTYSTQNFYYALVTSQLARLFGLGYLPILHGGNLPARLENSPRLSRMLFANAKVNVAPSLYLKSAFEAQGYTNISYIPNSIALDQYPVIKKEYAQPKLLWVRSFAALYNPNMAVQVLAGLRAKGYEASLCMIGPDKDGAFQNTKDLATQLQVEVAFTGKLTKPEWIEKSKAYNIFINTSTVDNMPVSVIEAMALGFPVVSTNVGGMPYLIADGENGILVDNGDVAGMVNAIVGLFEDEGRLELLSANARAFAGQFDWFEVRGRWMSVIEGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG04</accession>
    <name>A0A5C6ZG04_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase family 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12525</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="5"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="283" mass="32291" checksum="848EC76AD2D98D42" modified="2019-11-13" version="1">MNFHIIIPAHNEEDSIAKTLESLANQSLLPKKVVVVNDHSSDGTQGIVEAFASKYAWLSLVNNASSNAHLPGSKIINAFYKAYGTLDEDYDVICKFDADLIFPKQYLEQLAAHFSSNPKLGMAAGFCYIEKDGTWVLENLTRKDHIRGALKAYRKQCFLDIGKLKPSMGWDTVDELLAQFYGWELMTDDSLKVKHLKPTGMSYNKASKYLQGEAMYKMRYGFSITLISAVKLAYKKNSFKLFKDYLAGYFRAKNQNVERLVTEAQGKFIRKLRWDGMKEKFRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG09</accession>
    <name>A0A5C6ZG09_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF885 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_10970</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD89003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010281">
        <property type="entry name" value="DUF885"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33361">
        <property type="entry name" value="PTHR33361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05960">
        <property type="entry name" value="DUF885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="609" mass="69746" checksum="EB528ED4F1EB84D4" modified="2019-11-13" version="1">MKQLFLKSTLLLCTLTLLISCKEEKTEKAYTDVEIMAESKKVNDFFQKSFDARVDLSPEFQTRLGIKKDYGKLDDNSPEASERDLKINKEELVWLTDSVNAAALSKDALLSYKLYKQNVENSIDDYKYRLHNYPVNQMFGAQSGMPAFLVNMHRIDSVADAEAYISRLNGFNKYFAQVVENLKEREAIGIAPPKFVYDKVVQDSENILVGQPFDTSKTQSTLLEDFMNKVNKLEIDDEAKTTLEKQANQALLTSVKPAYEGLISFIKEQKERANTDDGAWKFPDGEAFYNNALKRTTTTDLTADEIHKIGLAEVARIHGEMDAIRQQVGFEGSLQDFFQFMRTDKQFYYSADQKGKDAYLKQAVHLIDSMKTRLDEIFISKPKADIVVKAVEPFREKSAGKAFYNRPAADGSRPGIYYANLYDMESMPNYQMEALAYHEGIPGHHMQLAIQQELEEVPMFRKFGGYTAYTEGWGLYSEFIPKEMGFYEDPYSDFGRLAMELWRACRLVVDTGIHSKNWTREQGIKYYTENTPNAEMDAVKMVERHIVMPGQATAYKIGMMKILELRQKAKDALGENFDIREFHEVVLSHGAIPLNVLEDFVDEYISSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG61</accession>
    <name>A0A5C6ZG61_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DEAD/DEAH box helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_11690</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="1">
        <location>
            <begin position="32"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="2">
        <location>
            <begin position="237"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="504" mass="58326" checksum="B78E9A5376F0C0EF" modified="2019-11-13" version="1">MANTVEIQSKKATKKQLYDYQIADLKRIFDVMENAPDNYNLLYQLPTGGGKTVVFSEIVRRYINNKKKKVVILTHRIELCKQTSKVLKGFGVNNKIINSKVKELPDQDQYQCFVAMVETLNNRLNDGKLRLEDIGLVIIDEAHYNSFRKLFKFFENCFILGVTATPLSSNIKLPMKDNYKELIVGDDISTLIGNGFLASAEMYNYDVSLSALKVGINGDYTVKSSEALYSNANMLGKLLFAYEELSKGKKTLIFNNGINTSRDVYYTFKRAGYNVRHLDNTCGKQERRDILKWFKNTPDGVLTSVSILTTGFDEPSVESIILNRATRSLTLYFQMIGRGSRINGDKTKFKVIDLGNNSIRFGPWSQPVDWQHIYKNPDYYLENLRHDEDIERDFVYEMPDSLKKRFKKNPNDDFDIQEEYKNVIRDGKKSMQAIENSIAQHSELVIANSEDIFEARALAKLLHDDICYRIKKYCHCIMNSTKNYKEWLLEEYIRKLRLSFNGKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG72</accession>
    <name>A0A5C6ZG72_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DoxX family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_10595</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032808">
        <property type="entry name" value="DoxX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13564">
        <property type="entry name" value="DoxX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="44"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="105"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD88935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="124" mass="13764" checksum="DB1213C7B79A769E" modified="2019-11-13" version="1">MDILITIFKLIVGLSLINVWILQRNKPTRWRGGDAQNITEEFQVYGLPLWSCYVIGSLKVLLGIALIISIWVPVLVAPAAIGLAVLLLGSIVMHLKIKDPLYKSFPAFLFMVLCISIAFQGQLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG82</accession>
    <name>A0A5C6ZG82_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="97" mass="11367" checksum="302795A81D1C2FEC" modified="2019-11-13" version="1">MTKPFENQKIKKRKFQRYFSYFLLGLALLLMLVQIAIINFKNGWNFDTILPLAVIFAVVLALLGHIIYNKRMRSRRKALKKIKKMSNSKVSAESSFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG96</accession>
    <name>A0A5C6ZG96_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF58 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_14115</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002881">
        <property type="entry name" value="DUF58"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01882">
        <property type="entry name" value="DUF58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF58" evidence="1">
        <location>
            <begin position="42"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="309" mass="36168" checksum="D59E9B647D69F7C4" modified="2019-11-13" version="1">MDLQAELNKTGGFKNLDLLAKQVVEGFVAGMHKSPFHGFSAEFAEHKIYNQGESTRHIDWKLFAKTDKLYTKRYDDETNLRCHLIIDNSSSMHYPDLKAFSISNLNKIAFSALASAALMQILKKQRDAVGMSIYSDAYDYYAPEKGSERHHQMLLSQLSAMASTKVENKQTETYTYLHQIAEKIHKRSLIFYFTDMLQTTSNDAKLYEALRHLKHNKHEVVLFHVFDGQKELKFDFDNRPRRFIDVETNEFINVYPDTIKEGYETAVKDYFKTIRLKCSQYQIKYVEADINKSFDRILTTYLVERQKFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGB6</accession>
    <name>A0A5C6ZGB6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GNAT family N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11975</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13508">
        <property type="entry name" value="Acetyltransf_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="155" mass="18395" checksum="36CAC2CC2CB9EFCE" modified="2019-11-13" version="1">MQMIEIIPYKKQYRSDFYKLNIEWLQTYFYVEPYDEEVLSKPETYILNKGGHIFFIKNDERILGTFALMPTANPACFELTKMAVLPAYRGQKIGQQLLQFAIDFAKRQSYESLMLYSNTKLENAIYLYRKYGFKELPVEPNAPYKRGNIKMELIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGH4</accession>
    <name>A0A5C6ZGH4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_15795</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="293" mass="33964" checksum="2491CB86233B6C19" modified="2019-11-13" version="1">MRIIHSLWTKPMLKNRWFLEGQIEPSIWLYALSFLYAKKVSTEVVLHTDTIGKTHLSCIPYDKIHLSLDELEDEHEKFWAFGKIKALENEPLGSIHIDGDVFFKSKAVIPYLNFKDHDVICQMVEGGHLFNEGYENQLPYFDNALKNTHIPGYGNVRKAFNCGVLGFNDLELKNQFLINFRTMVKCAKLDKAIMFKMDGKYEPNIIIEQYQLAGLCELNNYKVKFILDPVEVDKKNSLNMVAEELGFVHAWGKAKYTAAFQNKVKEKIKQVDSHLYKIIERHINMLNGQMILS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGL1</accession>
    <name>A0A5C6ZGL1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cbb3-type cytochrome oxidase assembly protein CcoS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ccoS</name>
        <name evidence="2" type="ORF">ESY86_11310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004714">
        <property type="entry name" value="Cyt_oxidase_maturation_cbb3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41532">
        <property type="entry name" value="PTHR41532"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03597">
        <property type="entry name" value="FixS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00847">
        <property type="entry name" value="ccoS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="61" mass="6927" checksum="4B8A893D9D6022BC" modified="2019-11-13" version="1">MSVIYILLSISIIVAVVFFIAFIMAVRSGQYDDSYTPSVRMLFDDELVKEDSKTKTDNSKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGN6</accession>
    <name>A0A5C6ZGN6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">T9SS type A sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_12750</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001590">
        <property type="entry name" value="Peptidase_M12B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50215">
        <property type="entry name" value="ADAM_MEPRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022792686" evidence="1">
        <location>
            <begin position="25"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase M12B" evidence="2">
        <location>
            <begin position="210"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50215"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="908" mass="97836" checksum="49D69FE3FFCB4DAA" modified="2019-11-13" version="1">MKNNYLKCISNFVFCILVSAPTFAQNPRSFWTEATPKQKLVAPVNADDFATMPSAKHYVQNIDQLKSALEDAPSRKGNSNPSNVILDFPNSRGSFDSYRILEASIMEEALQNKYPNMRSYVGQGVKNPSSLIRFSVTPKGLNTVAFTDQGIELIDISENGADNEYLVYNRRDVNNSQEEWICDFVDDVEDNTTFDESGLASRNANDGQMREFRLAIACTVEYAQFHGGTVPDVMAAMVEVMTSVNGVYEKDLSVTMVMVDNESIIFLGPDVESDPYTNSNSNAMLNQNQTTVDANIGVANYDIGHVFTTGGGGIAELRSPCTGSKARGVTGLPNPIGDRFALDFVAHEMGHQFGSPHTFNGNAGSNCLNQRTQSTAYEPGSGSTIMSYAGICSPQNVQLNSDGYFHQKSLQVMFDNITSGLSQCATLTPTGNSAPTADAGTNYTMPKSTPYKLTGSSTDPDGIASHTYTWEQYDLGPTGAPTETTLLGPIVRSRQGTVNPVRYIPRLEDIAVNGGVSAAWEKLAAISRPLNFRLTVRDNVIAGGQTATDIMTATVNADAGPFQVTSQSTNQIVWTPGDTETITWNVAGTTGNGINTANVNILLSTDKGVTYDTVLASNVPNDGSQDITVPNVSAAFCRVMVEAVGNIFFNVNEEFLAIGDYTYIPGNACQDYFFTADIQLEENASQFSGYTLPIPDSKTITDINVSVDVTTSNNAELVIGIRGPYNSPSGITYLLQNVNRCPGLPDVIVTFDDEGVVNPCTDTSNNIAIQPAQPLSAADGSNSQGDWVFFIGDVVVNNNFATWNNVTLTICEEGGFEPVLSTTNVGLDASFSVFPNPNNGEFTVKFNGTSGNVDLQVFDIRGRSVFNNSYDSAGEFNQTINLGNVQSGMYLLNVNTDAGKVTKKLIVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGP1</accession>
    <name>A0A5C6ZGP1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF3883 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11540</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024975">
        <property type="entry name" value="NOV_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13020">
        <property type="entry name" value="DUF3883"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3883" evidence="1">
        <location>
            <begin position="1368"/>
            <end position="1446"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1479" mass="174066" checksum="BA9716B430E320AF" modified="2019-11-13" version="1">MSIKKQVEKIITKRWEELRNPKNLIGLNNIEKQTNQGYNGRQLLELFQNCEDEGASKVKIYLDTEKRLLEISNDGDKPFSIKGYDSIFYPGLSSKVSSGYIGNKGLGFRSIINWADKISIISNDFKVVFDETLKKDIILNKIGYTESELSQIRRERKLNADVYPLPLLNCCRIEDVIDNSDFTTTISIRYKSEYEYRIKEQLESISEKTLLFLQNINTIEIDGNVLNKTISITRKKISENNSEISHNGQIYYVISDDGIVDENLIEDKESSQPKRYSVKIAYSNDLSFKDKVLYNYFKTQIPFELPFVAHASLELDQNRNHSTKSEVNPFILDKLFKLHLKFIEILKSKHFKSWLPYQTINNDKFSVYEPYSNVIDNYWENFEVYPILSGNYVNSSIAKNLGNRIAEFIQKNNLETYFGEQLVYCALPIEPQQYVSKPGNYKAIIESFAIHLNVAQRAELVSLLLEIYPNEKFCVLIDEKDNLIKTVDYVYTDKTTENKDLKVPYYSKIRFLNPELYIELLDKLQLQSETHKSRGLKDKLEKISDVHSFEPQTVIKKIISETTEYLKENENDKNKIIREFYQKLFYNYKLRAENPFLDYETEIPCLNQNDELLHIKSLALSDEFEIGKLSNQVFGDLYGNEYTITSLESLGLENENLIQVEEFLEWLGVNPFSIVEMVRAKIETEFINYSNHIHNTAISSYSLYNIRLFNKITNNGDITINHIIAWLSLDEKIKSIFKNYTEFYSSEEKLNYSHYGIKAIRPFKNFLYFKLSKQYDIQDYLITTKKQEWFNPFTIDYEYLFNINKDLDKEKVDGILSFFGAKKDFNDLDINYLKIKTQELAVRNNDKGSQVFYKNLVGHYKKNGQSMLGVDLYAKEGKDIVVKNSSQIYFSDRIQLPETLTNKFPLLYYPSRSGGARAIKMFGLMNLNNLDLKIETEERNLTISDDFEIMFKEIKPFILAFRLDKISKEDVKNDQVLLLNKLKIICCQELTCRLEDEIFAIEPYNYAYSKNQFYINIPIGSSMSQLKLNKQFRDNLSDIFLKVFDTLDEKKTFESIIMQSKEDNMYDVKNELAEGILEEANILLGELSVRLSIWKTIFRIKGLHVSSELNENNIDNCIFENFPELAEQKLFQSDDNLEELFRIRRVFTLLRIDLKDYNDVSDYKITFEKLFSNEIHRFYDERKKNIKNQLWFYLSSKEKDEQSNFIKYLHIIEHLLDTFHFTQNENKYNLELTLANLLKEKVPIMKFNLESEAYPEYDSIESENIKHFSDDEILDIRRSKTFNSLSYFKGHIDYIKAQLNKKEQQQKEEGHPVDFDLDIDQPSELIEEFEVVINPNGGWKQEGNGLWLGNKTELSSNQKKTLGNTVEEIVKKYLTERPLLYNKVELIAKTNESEHYDIKYYDVTQKQMRYVESKYYNGSSFILSRDEMEYGLKNAKQYEIWLVNKDSKIFVINDINKLGQLQPLKYRVEIKLQEYAIQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGP9</accession>
    <name>A0A5C6ZGP9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">SDR family oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_12800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="265" mass="29069" checksum="B6925B00E4534815" modified="2019-11-13" version="1">MTQEFKDKNYWALILGGSSGLGLATAKTLAKHGMNICIVHRNSRAKEAEIASEFEEIKAEGVAFKAFNTDAFKAEKRQQVISELKALFGPNGSLRTLVHSVAKGNLKPMWSEDKPMLKNDDFSLTINAMAISLYDWTKAIFEADLFSEDARIISFTSEGNTKAWKNYAAVSAAKVTLEAISRNIALEFAPFGIRANCIQAGVTDTASLRMIPGSEKLKAHSLLRNPFARLTQPEDVANAVYLLSKDEARWINGCVIPVDGGEHIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGR1</accession>
    <name>A0A5C6ZGR1_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Probable GTP-binding protein EngB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">engB</name>
        <name evidence="10" type="ORF">ESY86_09335</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Necessary for normal cell division and for the maintenance of normal septation.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01876">
        <property type="entry name" value="YihA_EngB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00321">
        <property type="entry name" value="GTPase_EngB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030393">
        <property type="entry name" value="G_ENGB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019987">
        <property type="entry name" value="GTP-bd_ribosome_bio_YsxC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03598">
        <property type="entry name" value="GTPase_YsxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51706">
        <property type="entry name" value="G_ENGB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="8" id="KW-0132">Cell division</keyword>
    <keyword evidence="6 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0717">Septation</keyword>
    <feature type="domain" description="EngB-type G" evidence="9">
        <location>
            <begin position="22"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD89307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="202" mass="23118" checksum="B3C9735DB8397B98" modified="2019-11-13" version="1">MIIKTAEFLMSNSDVDKCPKNQIPEYAFIGRSNVGKSSLINMITNHKNLAKTSGRPGKTQLINHFLINKEWFLVDLPGYGYARVSKTAKQKFQSFITDYFEKRQQLISAFVLIDIRHTPQPIDLEFMEYMGVSGIPFSIIFTKADKLKPMAIERNVNAYTEELLKTWEETPNYFVTSSSKNIGRDAVLEFIAATNTEIESMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH84</accession>
    <name>A0A5C6ZH84_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TIGR01777 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_12485</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAD(P)-dependent epimerase/dehydratase family. SDR39U1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013549">
        <property type="entry name" value="DUF1731"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010099">
        <property type="entry name" value="SDR39U1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08338">
        <property type="entry name" value="DUF1731"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01777">
        <property type="entry name" value="yfcH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="2">
        <location>
            <begin position="4"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1731" evidence="3">
        <location>
            <begin position="249"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="298" mass="33096" checksum="1CEC713D0DE0029F" modified="2019-11-13" version="1">MKTITIAGGSGFLGQVLVQHFTKKGHEVFILSRNPKRENDTLWNAKDLGAWTKILEKTDVLINLTGKSVDCRYTEANRKLILASRIDATEVLGLAINLCENPPALWLNSSTATIYEDSQIKQMTEEHGDLGDDFSMNIAKSWEHSFYKITNPKTRKIALRTAIVFGKNGGALIPLKNLVTFGLGGKQASGKQKVSWIHEQDFARAVEFLMENESLNGNFNLSVAKPTNNKTLMKTLRSVMHMPIGLPQPKWLIKLGAKLIGTEPELVLKSRNVIPQRLSGKGFVFLQGDLEPTLKSLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHC6</accession>
    <name>A0A5C6ZHC6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">T9SS type A sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_14215</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Por_Secre_tail" evidence="1">
        <location>
            <begin position="308"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="379" mass="40126" checksum="C5A4ED58C3F4C063" modified="2019-11-13" version="1">MKKITFLFTMVIATSSIFGQVLSEDFESGLAVPSGWTVEDVAMNTPPEIWTIETGGEAGGFTAGNTAVYDNGGDGNYATFDSDGYGNNGTAEESTLTSPVFDCSSLSSVTLSFATVYNGNFGGQGVIEVYNGTAWVNLITYATEAGGAPSTTLTGIQILDVPQLVGVSNAQIRFVWTGNWSISWTIDNISVFECTETESPSTVSAPSPADGAEDVSISAVNNGLTFSWTEGSVTSASFTLNFGTANPPAQSFEGFSNGGTITGLQENTQYFWSVDPVNCFGTTTGTVYSFTTGTVLSVDKKEVTQFTVFPNPVNDKVEIITKANIDHIIVTNQLGQQMMSVNASALNGNMLDMSSLTAGMYFISVSSENKTETIKIIKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHE0</accession>
    <name>A0A5C6ZHE0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08425</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022966141" evidence="1">
        <location>
            <begin position="19"/>
            <end position="1136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1136" mass="129644" checksum="92AB139CF41ABF60" modified="2019-11-13" version="1">MRLVLFFMSFIVASSAFAQEPSSNYRTQKMAARDSIRVDSVSINPSWFLLKRKDGSSIDTAFYKIDFSKALLTFKKPVATDSVEIAYLRYPDFLTRKYFLLDDKIIVNNTNDLQRLYKLNQSNLENAFTPFDGLSTSGSISRGVTIGNNQNSVLNSELDLQISGKLSDKVSLRASIQDANIPLQESGYSQRLDEFDQVFIELFSDRWNIRAGDIDLVNNDSYFASFTKRVQGLLVNVNLGDEDAKTNIFASGALVRGQFTTSQFIAQEGNQGPYKLRGPNNELFVLIVSGSETVYVNGIALERGENDDYIIDYNAGEIIFNATYPITSEMRITVDYQYSERNYSRFIVFGGGSHTTEKFKLGVSVYSETDAKNQPLQQNLSSEQVGLLSEAGDDQALMVAPSAVEQAFSENRILYTKELINGAEALVFSNNPEDQLFSVKFSLVGDNQGDYILISNNAVENIYEYVAAIDGIPQGNYAPIVKLIAPEKLQVAVVNGRYAPSEKTELYFELVGSKNDINLFSSLDDADNDGFAGKIGVKQNIIQTDSLWNLNVYADADVIHENFKTVQRLYRAEFDRDWSLEDPLGNQMLLTSGAELVHPQKGIANYKFEHLNYSENFNGNRHNLLANLFLKRWSIYTHSSILNNSTSLSNTRFLRSYNRVTYSFNKQWVGTKIALEDNEQREKETDLLTNLSQRFHSYEAFTGYGDSTGVFVEVGYKYRVNDSLRANRVERVNKSNTYYLDSKLIQNQNTNLGIYVNYRTLKSDDPAFEDERSLNSRLNYNQQLFNNGISFNSIFETNSGSLAQQDFTYVEVEPGQGAYTWIDYNDNGIQELNEFELAQFADQGSFIRVLLPNQVFVKTHQNRFSQTLTLNPQQWSESENAWRKSLSHFYNQTSFLVDRKNKRDGNTFDLNPFSSNDDNQLALNKSIRNVLFYNRGKQRYTTSYTFLNNKTRNVLSIGFQQNNLRSHQLQFNHKFATSWLMNLKSSVEKNTSESENFSSRNYELEELRLQPKLSYIFNENARFDIFYQYTSKDNGIGEMEQLLQNNYGMSFTYNSTNQVALTGEVNFFKNEFTGNANTPVSYQILEGLQPGNNFTWSLLAQKKLTQFLDLNLNYFGRKTETSKTIHTGTVQLKAYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHG6</accession>
    <name>A0A5C6ZHG6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023098870" evidence="1">
        <location>
            <begin position="25"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="346" mass="36879" checksum="B84CBEF5ECE8430F" modified="2019-11-13" version="1">MKTLKITILCSLLSLFSFSQTVHTVDNRDQSGAQFTNLQTAIDAASAGDIIQVYPSEDSYGAVDVGKSLTLMGFGHNPANTDGEVATISTITFRNNSAGSEIKGLSISSIRCSSSTTSPDQDNIRIINNRINAGVTGSTTDNLSDNWVIEGNYFTSTGDNVNPQNGTNNWQIKNNFMRGYLISLNNTCIVTNNIFLSTSSSAIFFYNSDGPLVNNNIFLATGTLTEIGTSPSTITFVSNITYSFYGATIAALAGSNNLNNTNPLFVNVPSDAVTDFYNNNYDLTSGSPGINAGSDGTDIGLFGNNFLFDPNGRPNLTPYPESITITNSVVAPGQTLNVNFTATQKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHI6</accession>
    <name>A0A5C6ZHI6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycoside hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_09080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022838444" evidence="1">
        <location>
            <begin position="21"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="334" mass="38938" checksum="08293A8E9F263DF4" modified="2019-11-13" version="1">MTYFKWFVCCLLLTACFAKIETTEKIDAVSFVASRHPIDSSHTKALQPLNANYAALMPFGFIKDLAHPDIIYNTDRQWFGETEAGVKQYAETLRKANIKIMVKPQIWVWRGEFTGNIKMTTEADWQLLEAAYTKFILEYAHVAKDIHAEVFCIGTELENFVVERPEYWEQLIAKIKTIYHGKLTYAANWDEYRRTPFWDDLDYIGVDAYFPVSQMKTPTVADCRAGWQKHKTLLKSISEDKNKPILFTEFGYRSMDFAGNEHWQSDHNIKTLNLEGQANATEALFEEFWTEPWFAGGFVWKWHQDHHERGGDVDNQFTPQNKPAQEVIARFYGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHP2</accession>
    <name>A0A5C6ZHP2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">RNA polymerase sigma factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_07635</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="22"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="3">
        <location>
            <begin position="117"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="180" mass="20872" checksum="370785579601364A" modified="2019-11-13" version="1">MSLKQLIDDCKRNDTQAQSQIYKLYASKLFSICLKYSRNYAEAEDNLQDAFITIFKKIDQFKAKGSFEGWLKRITVNTALQRYRSVGVFDIVNEDQIEEVTIEMDDDNISLDFLLGIIQELPDRYRLVFNLYVMDDYPHKEIASLLEISTGTSKSNLARARSILKDKIEQYKAKSNSQSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHP5</accession>
    <name>A0A5C6ZHP5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Arsenate reductase (Glutaredoxin)</fullName>
            <ecNumber evidence="3">1.20.4.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">arsC</name>
        <name evidence="3" type="ORF">ESY86_11935</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the ArsC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.20.4.1" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008794">
        <property type="term" value="F:arsenate reductase (glutaredoxin) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd03034">
        <property type="entry name" value="ArsC_ArsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006659">
        <property type="entry name" value="Arsenate_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006660">
        <property type="entry name" value="Arsenate_reductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30041">
        <property type="entry name" value="PTHR30041"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03960">
        <property type="entry name" value="ArsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00014">
        <property type="entry name" value="arsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51353">
        <property type="entry name" value="ARSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="113" mass="12844" checksum="BA08A6D3CA8D65B3" modified="2019-11-13" version="1">MITIYHNPRCSKSRQGLEILKNSGQEFEIINYLKDPLSEEKLRQILALLNIAPIALVRQNETIWKSDYKGKTLTEDEIISAMAKHPKLIERPIVINQDKAIIGRPPALIASLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHU8</accession>
    <name>A0A5C6ZHU8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bifunctional response regulator/alkaline phosphatase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_10375</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013973">
        <property type="entry name" value="PglZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08665">
        <property type="entry name" value="PglZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="5"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="517" mass="59798" checksum="2A59587D1B8430D7" modified="2019-11-13" version="1">MNTINILWVDDEIDLLKPHILFLEKKQYKVTTCQSGTEALEIIDDTNFDIVFLDENMPGLTGLETLNEIKSRRANLPVVMITKSEEEYIMEEAIGNKIADYLIKPVNPNQILLSLKKNLDHSRLVSEKTTSNYQQEFRKIAMDLSMVNSYKEWIDLYQKLIYWELQLEDIEDVGMTEILESQKTEANTQFGKFIEKNYPHWFDKDSDAPILSHTLFKEKVVPELSDDQPTLLVVIDNLRYDQWRAFEPIVSNYYKKTDETPFFSILPTATQYARNAIFSGLMPSDMEKQHPEFWKNDTDDGGKNMHEADFLQAQLKRLGLQNLKTEYHKITNLKAGKKLVENFKTLKSNDLSVIVYNFVDMLSHSKTEMDVVKELASNDKAYRSLTQSWFKNSPLLEMIQQAQHLGFKLILTTDHGTINVKNPSKVIGDRDTSLNLRYKTGRSLTYEGKDVLVAKDPKSIKLPSLTMSSSFIFAKGDYFLAYPNNYNHYVGYFRNTYQHGGVSLEEMIIPFVVMSPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHV5</accession>
    <name>A0A5C6ZHV5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GDP-L-fucose synthase</fullName>
            <ecNumber evidence="2">1.1.1.271</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">fcl</name>
        <name evidence="4" type="ORF">ESY86_07970</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>GDP-beta-L-fucose + NADP(+) = GDP-4-dehydro-alpha-D-rhamnose + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:18885"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57273"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57964"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.271"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Nucleotide-sugar biosynthesis; GDP-L-fucose biosynthesis via de novo pathway; GDP-L-fucose from GDP-alpha-D-mannose: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.271" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00128">
        <property type="reaction ID" value="UER00191"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050577">
        <property type="term" value="F:GDP-L-fucose synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070401">
        <property type="term" value="F:NADP+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042351">
        <property type="term" value="P:'de novo' GDP-L-fucose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05239">
        <property type="entry name" value="GDP_FS_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00956">
        <property type="entry name" value="GDP_fucose_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028614">
        <property type="entry name" value="GDP_fucose/colitose_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="3">
        <location>
            <begin position="7"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="2">
        <location>
            <position position="137"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="11"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="106"/>
            <end position="109"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="164"/>
            <end position="167"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="239"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="311"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="2">
        <location>
            <position position="108"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="2">
        <location>
            <position position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="348" mass="39482" checksum="735B6D335AC786D6" modified="2019-11-13" version="1">MEKKSKIYIAGHRGLVGSAIFENLQQKGYSNIVTRTHAQLDLSNQMAVQEFFELEIPEYVFLAAAKVGGIIANNVYRADFIYENMMIQNNVIHQSHLHNVKKLLFLGSTCIYPKNAPQPMKESYLLTDTLEYTNEPYAIAKIAGIKMCESYNLQYGTNFISVMPTNLYGPNDNFDLEKSHVLPALIRKLHLAKLLSENNEDAILKDTGFKTLAEAKNYLSEFGVSSESVEIWGSGAPKREFLWSKDMADACVFIMENRDFKDTYSEADKETRNTHINIGTGEDISIKDLAEMIKTIVGFEGKLVYNTNKPDGTLRKLTDVSKLNALGWKHKMNLKNGISEVYDWYKNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHY4</accession>
    <name>A0A5C6ZHY4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07165</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="208" mass="23556" checksum="E6999465D500951F" modified="2019-11-13" version="1">MKKISPYKQIDEALLALDNGGRFYNILTKSNDGIISQSELGKIGGLFNDKQKMILFLEMSMISFEDEEKEIILSKLDGDLKQTYLKYKSQKLLPSEANEKGILASNAILTGVPKLVDKKSDFNGFIMVPIMAGKAMIFVMIPIIDNYNIYELRDEKTSDTFIIAHSRNSEKLPNKKIIIAGLLKELKSEKNEDSKTVKFLEANYYISN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHZ2</accession>
    <name>A0A5C6ZHZ2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sigma-70 family RNA polymerase sigma factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_12495</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="12"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="3">
        <location>
            <begin position="123"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="183" mass="21361" checksum="99987D0821EDB304" modified="2019-11-13" version="1">MLDHTIDPNTWISNYADYMFNYAITRVNDREMAKDLVQDTFVAGLKSMENFKGEASERTWLISILKRKIIDYYRKKNSKKGQAEVRVGYMNEDQEGDWLEERVADPFSKDAQDIIENAELGKAISECMAKLPKKQKQVFEMKTILDYETKAICNELGITSSNLWVIIHRARITLADCMKKNWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI58</accession>
    <name>A0A5C6ZI58_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Translation initiation factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_11715</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SUI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd11567">
        <property type="entry name" value="YciH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001950">
        <property type="entry name" value="SUI1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005872">
        <property type="entry name" value="SUI1_arc_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036877">
        <property type="entry name" value="SUI1_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01253">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55159">
        <property type="entry name" value="SSF55159"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50296">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0810">Translation regulation</keyword>
    <feature type="domain" description="SUI1" evidence="5">
        <location>
            <begin position="43"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD88631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="111" mass="12696" checksum="B8EF68C790488880" modified="2019-11-13" version="1">MDLQDQLKNLFPDHEPDENPSEEKKSEKQGIWLQEDPILCKYEKRKGKPITILEGYTGADQDFKKLAKELKTTLGVGGSFKNDKIIIQGDYRVQIMEILKDKGFNVKRVGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI63</accession>
    <name>A0A5C6ZI63_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glutamate--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Glutamyl-tRNA synthetase</fullName>
            <shortName evidence="8">GluRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">gltX</name>
        <name evidence="12" type="ORF">ESY86_12635</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu)</text>
            <dbReference type="Rhea" id="RHEA:23540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9663"/>
            <dbReference type="Rhea" id="RHEA-COMP:9680"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.17"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.17" evidence="8"/>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004818">
        <property type="term" value="F:glutamate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006424">
        <property type="term" value="P:glutamyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00808">
        <property type="entry name" value="GluRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00022">
        <property type="entry name" value="Glu_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045462">
        <property type="entry name" value="aa-tRNA-synth_I_cd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020751">
        <property type="entry name" value="aa-tRNA-synth_I_codon-bd_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008925">
        <property type="entry name" value="aa_tRNA-synth_I_cd-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004527">
        <property type="entry name" value="Glu-tRNA-ligase_bac/mito"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000924">
        <property type="entry name" value="Glu/Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020058">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020061">
        <property type="entry name" value="Glu_tRNA_lig_a-bdl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033910">
        <property type="entry name" value="GluRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19269">
        <property type="entry name" value="Anticodon_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00749">
        <property type="entry name" value="tRNA-synt_1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00987">
        <property type="entry name" value="TRNASYNTHGLU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48163">
        <property type="entry name" value="SSF48163"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00464">
        <property type="entry name" value="gltX_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1c" evidence="10">
        <location>
            <begin position="5"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_2" evidence="11">
        <location>
            <begin position="360"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="8">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="8">
        <location>
            <begin position="260"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF19269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TXD88361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="503" mass="57502" checksum="4EC368FFCEAD4A12" modified="2019-11-13" version="1">MNKPVRVRFAPSPTGPLHIGGVRTALFNYLFAKKHKGTFVLRIEDTDQTRYVAGAEDYIVKALNWCGIPFDEGPNKNEKFGPYRQSERKDLYKKYADQLIESGHAYYAFDTAETLDFHRKDHEAKGKTFIYNWHNRQKLDNSLSLSAEAVQQKLDANEDHVVRFKSPQDETLHLTDMIRGDIEIDTNILDDKVLFKSDGMPTYHLANIVDDHLMQISHVIRGEEWVPSLALHYQLYDAFGWDIPQFAHLPLILKPTGKGKLSKRDGDKMGFPVFPLEWTDAETGAVSAGYKENGYFPEAMVNFLALLGWNPGTEQEIFTLEILSNVFELERVNKGGARFDPDKIKWFNHHYMQEQHDADLAKAYKASHKALADIDIQYIELVVALIKERATFVSDFWELSSFFFVAPKDFDDKAYKKAIKDDTPELMTQLIQKVTTNAEFTIESLQEDIKSWITDNNIGFGKVMMPLRLALVGALQGPDVFDIMFMIGKAETVKRIDTLLASI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIM1</accession>
    <name>A0A5C6ZIM1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Metal ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_07305</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ABC-3 integral membrane protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001626">
        <property type="entry name" value="ABC_TroCD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30477">
        <property type="entry name" value="PTHR30477"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00950">
        <property type="entry name" value="ABC-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="37"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="60"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="175"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="204"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="231"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="257"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD89586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="386" mass="42190" checksum="02598BE3BA66F71E" modified="2019-11-13" version="1">MSSAQFEIQLIASIVAIACAIPGTFLVLRKMAMISDAISHSILPGIVVGFFITQDLNSPWLILLAAFTGVITVVLVENIQKTGLVKEDTAIGLVFPVLFSIGVILIAKNANDVHLDIDAVLLGELAFAPFDRIYMGGVDVGPKSLWVIGSILLITITLLILFFKELKLSTFDKGLSASLGFSPIVIHYGLMSVASVTTVGAFDAVGAILVVALMIAPAASAYLLTTDLKKMLLLSIGFGILSAISGYWMAYWLDASIAGSITTMLGILFLVVYLFAPSKGIIAVLYREKQQRTEVSLLTFLLHLKNHEEESERHVKHLNEHINWQKVRSRTVLDLALKNNMIAIDNKIVSLTPKGDEFTTQAIDYIITNEDAQIEDMKDDFFLFRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIS5</accession>
    <name>A0A5C6ZIS5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_10350</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the DegT/DnrJ/EryC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00616">
        <property type="entry name" value="AHBA_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000653">
        <property type="entry name" value="DegT/StrS_aminotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30244">
        <property type="entry name" value="PTHR30244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01041">
        <property type="entry name" value="DegT_DnrJ_EryC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000390">
        <property type="entry name" value="PLP_StrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="334" mass="36966" checksum="D243295BBCC356E2" modified="2019-11-13" version="1" fragment="single">MDSKIWLSSPHLGTKERAFINEAFQSNWIAPSGKLVDGFESDISNYLGNEQHVAALNSGTAAIHLALVLLNVAAGDEVLCQSHTFAASANPIIYQGATPIFIDSEALSWNLCPELLEQAIKDRIKKGKTPKAIIAVHLYGMPYQVDEIQAIAAHYNIPIIEDSAEAFGSRFENKMCGTFGSMAILSFNGNKIITTSAGGALITKDKFLRDKAVFLATQAKDDHAAYTHSNIGYNYRMSNVLAGIGRAQMEVLDSRVTARRNNFKVYSEALAHLSELKFQQEPKNCVSNRWLTCVLTPSEEVREGLRKHLESLNIESRPFWRPMHLQPVFKDAPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIY2</accession>
    <name>A0A5C6ZIY2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">GH3 auxin-responsive promoter family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_08010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004993">
        <property type="entry name" value="GH3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31901">
        <property type="entry name" value="PTHR31901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03321">
        <property type="entry name" value="GH3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="500" mass="56675" checksum="AFA8DA696212ED93" modified="2019-11-13" version="1">MLSIKPFLAKLFAKSVKRSVLKWVNTPLETQQKVFEKLIEEASHTVFGQDHGFSEIKTYQDFAKRVPIRDYEDLKPYVDRVVAGEEDVLWKGKPLYFAKTSGTTSGAKYIPLTKESMPTHVEAARNAILLYIAETGNSGLVDGKMIFLQGSPILNEKNGIQLGRLSGIVAHYVPKYLQKNRMPSWETNCIEDWETKVEAIVEETLPEDMTVISGIPSWVQMYFEKILEKTGKKVGEVFPNFNLFIFGGVNFEPYRSKFENLIGRKVDSIELYPASEGFFAYQDKQHEKGMLLQLNSGMFYEFVEAETFFEEQPERLTIANVKTGVNYVMLISTNAGLWAYNIGDTIQFTSIKPYRIIVSGRIKHFISAFGEHVIGSEVEQALKIATEVSKIQVSEFTVAPQINPSAGLPYHEWFIEFENEPENPSALAKDIDQSLQNQNSYYKDLILGKVLQPLKITAVKKNGFQDYMKSIGKLGGQNKLPRLANDRKIADALLQEDLLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIY4</accession>
    <name>A0A5C6ZIY4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4386 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05560</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025495">
        <property type="entry name" value="DUF4386"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14329">
        <property type="entry name" value="DUF4386"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="206"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="240" mass="27066" checksum="3DA81BBC9FB1DEEC" modified="2019-11-13" version="1">MEEISRNKKARLAGILYLLLVISGFIYLVYIPLELIDLNNAAKTLENIQSSELLFRLGIVTAICSSLIFMLLPLALYSLLKSVNKVSAKFMVLFALISIPISFINILNKFSVLTLINKSEYAEKLGQTELQTQVILYLENYNNGVQLSQVFWGLWLLPFGYLVYKSGFLPKILGIFLMAGCFGYLITFFGGFLYPDFNKTIVSDIVGFPAPIGEIGICLWLLIMGTNKLNIRRKPLIDNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ48</accession>
    <name>A0A5C6ZJ48_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="163" mass="18789" checksum="EE740C40593FDD18" modified="2019-11-13" version="1">MGYMGFGMANWVFKQRSRKAFAKRSTKPTSNTLPLYKRQFKLQPSKKSSRLHSIFTWMLIVLVSVGLFVKIPEFMAHSRAIAIQNQERMQRLDAEAFSFLMRAGQAQLMRDDLLAAYHEFLLAQKIKPKDEHLNQLILETLSSLCENENQFCGKLDNAMSKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJC0</accession>
    <name>A0A5C6ZJC0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Aldehyde dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_05935</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="5">
        <location>
            <begin position="19"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="249"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD90274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="480" mass="52557" checksum="A3AF07F92D65355E" modified="2019-11-13" version="1">MANIKNYINGSFQNPINNEWIDNYNPSNGEVYGQIPSSSQEDVEQAYQAAKSAFPKWSQTTLDERSRILIKISELLEAHLQAFAEAESKDNGKPISVAKSVDIPRAASNFRFFGNAITQFASESHESIGQNAINYTLRQPIGVVGCISPWNLPLYLFTWKIAPAIAAGNCVVAKPSEITPMTAFLLGDLCNKAGLPKGVLNIVHGLGGTTGQAIVEHPNIKAISFTGGTATGAHIARVAAPMFKKLSLELGGKNPNIIFADCDYEDMLDTTVRSSFANQGQICLCGSRIFVEAAIYEQFKTDFVAKVKQLRVGHPSEATTDIGALVSKAHLEKVKQYIKIAKEEHGSILCGGNEVTIEGFESGYYLEPTVIEVQTNDCRVNQEEIFGPVVSIMPFETEADVLTMANDVKYGLSATLWTNDLKRTMRMSNQLQAGIVWVNTWMMRDLRTPFGGIKASGVGREGGFEALRFFTEAKNVCIKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJE2</accession>
    <name>A0A5C6ZJE2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Tryptophan 2,3-dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_08610</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004833">
        <property type="term" value="F:tryptophan 2,3-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037217">
        <property type="entry name" value="Trp/Indoleamine_2_3_dOase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004981">
        <property type="entry name" value="Trp_2_3_dOase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10138">
        <property type="entry name" value="PTHR10138"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03301">
        <property type="entry name" value="Trp_dioxygenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140959">
        <property type="entry name" value="SSF140959"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="311" mass="37391" checksum="C4C5500AB4A85B07" modified="2019-11-13" version="1">MDDLHKFDGIVKQLQKKFTDIDQDTDDHLHGLLYSKPITYWDYIQTDALLNLQIQRTTLPDEMVFIAYHQINELIFKMILWEIDQLAQKENLEVSFFENKLMRISRYFDMLTTSFNIMREGMDVEQYMKFRYTLTPASGFQSAQYRMIEFASTELINLIDYRFRKTIDRNTPFEHAFEHLYWQAAGKDYNTGKKSTLLVNFEKRYKGDFIRFMQTYNTKNLWSRFKELPKKDQENTDLIKAMRHYDYTVNITWVIAHYNAAKHYIESGTGDGEATGGSDWKKYMHPKYQKRIFFPELWSENEIDNWGDDLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJH5</accession>
    <name>A0A5C6ZJH5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08775</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022727813" evidence="1">
        <location>
            <begin position="23"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="205" mass="23090" checksum="3A7198CF43E2930E" modified="2019-11-13" version="1">MKNMLRLTLVAMLLIACKDANQAKTMEGAVNEAIGNNEDVNQKYDHLLKELNKITPLTNAQLLKAFPEKLGNLSLDASGKGSNETRITSSETVVGSFGDNKVRMEILDAAGKNAYGAIIPLKMLQLNKVTSESNNTIRYSKKERNALLIFGTDRDEDTKADYQSELRLLYDNRFYITLEGKQMQVDELWGAINMDDLTRFKDYNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJQ5</accession>
    <name>A0A5C6ZJQ5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L28</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpmB</name>
        <name evidence="5" type="ORF">ESY86_03950</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.170.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00373">
        <property type="entry name" value="Ribosomal_L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034704">
        <property type="entry name" value="L28p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026569">
        <property type="entry name" value="Ribo_L28/L24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037147">
        <property type="entry name" value="Ribo_L28/L24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001383">
        <property type="entry name" value="Ribosomal_L28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13528">
        <property type="entry name" value="PTHR13528"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00830">
        <property type="entry name" value="Ribosomal_L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143800">
        <property type="entry name" value="SSF143800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00009">
        <property type="entry name" value="L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="78" mass="8740" checksum="C26AEAD5592B7A80" modified="2019-11-13" version="1">MSRVCELTGKKAMVGNNVSHAMNKTKRKFDANLIKKRFYIPEEDKWITLKVATSALKTINKIGISAALKEAKSKGFIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJR3</accession>
    <name>A0A5C6ZJR3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2207 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_04705</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="61" mass="6501" checksum="C0203866D23A7ADD" modified="2019-11-13" version="1">MIRILALILTIGGMIALVLGVLGIFGNNLVALSPWALAILGGIFFISGVSMLKYRKDEPTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK27</accession>
    <name>A0A5C6ZK27_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07835</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045625">
        <property type="entry name" value="DUF6427"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19992">
        <property type="entry name" value="DUF6427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="239"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="264"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="307" mass="35305" checksum="3764BCA3F396D922" modified="2019-11-13" version="1">MLSNFFSKSKPIHYLILGFSLLFIFAAAKFSVLEPNLSLLMVSKQLGLFLVCLGSVFIFDFFVTKNKLTQKNSFKMLLFVLFIAVLPETILNTRILLANFFLILALRRMLSLRTHKMVKKKLFDAAFWIAVATLFYFWCILFFILLFTALLVYSFTDIKNYIIPLTGIATVAILAVSYQLVLGYDLSAYYESQTDFSFDFTALNSKRLIIGATLLFSFGLWSLFYYLRNIKSKTKSYRPTFKLIVVTALLAVVIIVLAPSKDGSEFIFLFAPLAIIMTNYLELISEKWFKETFLWILVLTPIFISLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK28</accession>
    <name>A0A5C6ZK28_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_04130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="141" mass="16572" checksum="3B87C6900F968CF4" modified="2019-11-13" version="1">MKAKPLEVFDHDTDVDTTHKNNSIELDHWINHLSSIKKELFNLVELCSADLNLGKAENDVLKRLQKKEDENENLLNAMLSYSTSRTNIIECEDTQCDIFYIAEHETYRSSYDYQIDKYQGLKDRFFKEEHGKISLIEVPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK46</accession>
    <name>A0A5C6ZK46_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UDP-N-acetylglucosamine 4,6-dehydratase (Inverting)</fullName>
            <ecNumber evidence="3">4.2.1.115</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pseB</name>
        <name evidence="3" type="ORF">ESY86_07935</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the polysaccharide synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.115" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05237">
        <property type="entry name" value="UDP_invert_4-6DH_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003869">
        <property type="entry name" value="Polysac_CapD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020025">
        <property type="entry name" value="PseB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02719">
        <property type="entry name" value="Polysacc_synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03589">
        <property type="entry name" value="PseB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Polysacc_synt_2" evidence="2">
        <location>
            <begin position="9"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="339" mass="37932" checksum="FFC9195EC731AB36" modified="2019-11-13" version="1">MLNLKGKSLLITGGTGSLGKALTEHILNKYPDIRRLVIYSRDEQKQFQMAQEYPSETYPQIRYFIGDVRDKDRLERAFQGVDFVIHAAAMKHVHIAEYNPDECIKTNIGGAENVVAACFKTKVERVVALSTDKACAPINLYGATKLTSDKLFVAANNIKGENPIRFSVVRYGNVMGSNGSVIPFFINKKKESNTLPITDPNMTRFNISLQGGVDMVMHALEHAWGGELFVPKIPSYRITDVAEAIGPNCEKPVVGIRPGEKVHEEMITASDSFYTYDLGKYYTILPATHKWSIEEFIATFNAKKVPMGFSYNSGDNENLETVEGLRELIKKHVDPNFEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKB2</accession>
    <name>A0A5C6ZKB2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase family 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_04525</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="1"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="246" mass="28893" checksum="BA1EF7E2BCD791CA" modified="2019-11-13" version="1">MITYNEIGHIKEAISNLEFADEIIVIDSFSTDGTFEALSTMNHVKIVQRAFQNFADQRNFAIDQATRDWIFFMDADERLTQASQEEIVETVKHNNGIEAFKIPRRFMFNDKMMRFSGLQTDRVFRLFKRGVTKYRKDKLVHEVLDFTGEFAVLTHEMLHYSFSDYESYKKKTEHYGCLKAQELFKKGKTPNAFHFYIKPAYKFLANYVFRLGFLDGREGYTICSLNAYGVFFRYKVLEKLLSGAPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKG0</accession>
    <name>A0A5C6ZKG0_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Recombination protein RecR</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">recR</name>
        <name evidence="9" type="ORF">ESY86_04805</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the RecR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01025">
        <property type="entry name" value="TOPRIM_recR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00017">
        <property type="entry name" value="RecR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000093">
        <property type="entry name" value="DNA_Rcmb_RecR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023627">
        <property type="entry name" value="Rcmb_RecR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023628">
        <property type="entry name" value="Rcmb_RecR_C4-type_Zn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034137">
        <property type="entry name" value="TOPRIM_RecR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30446">
        <property type="entry name" value="PTHR30446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02132">
        <property type="entry name" value="RecR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13662">
        <property type="entry name" value="Toprim_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111304">
        <property type="entry name" value="SSF111304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00615">
        <property type="entry name" value="recR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5 7" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6 7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Toprim" evidence="8">
        <location>
            <begin position="81"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="7">
        <location>
            <begin position="58"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD90075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="205" mass="22856" checksum="205788EBE663C717" modified="2019-11-13" version="1">MEFSSKLLENAVNEMSQLPGIGKRTALRLMLHLLRQPKEQTSDLSKALSNMRNDIKLCKNCNNISDNDLCEICANPNRLEDIVCVVEDIRDVMAIENTSSFRGLYHVLGGKISPMDGIGPNDLNIQPLVKKVKSGKITELIFALGSTMEGDTTNFYIYKQIQEFKVKTSTIARGISVGNELEYTDEVTLGRSIINRIPFEASLKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKG5</accession>
    <name>A0A5C6ZKG5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Methionine aminopeptidase</fullName>
            <shortName evidence="2">MAP</shortName>
            <shortName evidence="2">MetAP</shortName>
            <ecNumber evidence="2 3">3.4.11.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Peptidase M</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 5" type="primary">map</name>
        <name evidence="5" type="ORF">ESY86_06030</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 2">Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 3">
            <text>Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides.</text>
            <dbReference type="EC" id="3.4.11.18"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="2 3">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="2 3">Binds 2 divalent metal cations per subunit. Has a high-affinity and a low affinity metal-binding site. The true nature of the physiological cofactor is under debate. The enzyme is active with cobalt, zinc, manganese or divalent iron ions. Most likely, methionine aminopeptidases function as mononuclear Fe(2+)-metalloproteases under physiological conditions, and the catalytically relevant metal-binding site has been assigned to the histidine-containing high-affinity site.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.18" evidence="2 3"/>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070084">
        <property type="term" value="P:protein initiator methionine removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01086">
        <property type="entry name" value="MetAP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01974">
        <property type="entry name" value="MetAP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001714">
        <property type="entry name" value="Pept_M24_MAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002467">
        <property type="entry name" value="Pept_M24A_MAP1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00599">
        <property type="entry name" value="MAPEPTIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00500">
        <property type="entry name" value="met_pdase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 5" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 3" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M24" evidence="4">
        <location>
            <begin position="11"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="105"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="267" mass="29335" checksum="54E20E9846B2E433" modified="2019-11-13" version="1">MIIAKTREEIELMRQSALVVSKTLGMLAKEVKVGMTTKKLDTLAEDFIRAQGAIPGFLGLYDCPSTLLCSINEAVVHGLPTNVPLKEGDIVSIDCGAILNDFYGDHAYTFEIGEVAPETKKLIQTTKESLYMGIRALKLGNRVGDVGFAIQNHCEAEGYGVVRELVGHGLGRKMHEDPEMPNYGRRGRGKKFIEGMVVAIEPMINLGTHKVKQLSDGWTIVTLDGKPSVHFEHDVAIIDGKPEILSTFGYVHEALGISSLEEDEFRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKJ9</accession>
    <name>A0A5C6ZKJ9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">T9SS type A sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_06640</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008754">
        <property type="entry name" value="Peptidase_M43"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022409">
        <property type="entry name" value="PKD/Chitinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000601">
        <property type="entry name" value="PKD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035986">
        <property type="entry name" value="PKD_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05572">
        <property type="entry name" value="Peptidase_M43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00089">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49299">
        <property type="entry name" value="SSF49299"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50093">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022972868" evidence="1">
        <location>
            <begin position="28"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="domain" description="PKD" evidence="2">
        <location>
            <begin position="329"/>
            <end position="375"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="582" mass="63709" checksum="A01771707F7F9A56" modified="2019-11-13" version="1">MLKKLLHSVPKMSVFVMIMCCVSLMSAQDEAQCGTLETPESETIFQDMLPRLRNIESNYMQSSMSRTPSSKSFVPIKAHILRRSDGTGGLTQSQLDDAIAEMNVFYANASMEFFICDAINYIDDTDFYDFEPSEEYSLTNSRDVDNVVNIYFANSVASNTGNSLCGYAYYPGGPERILMKNSCTTNGSTLAHEMGHFFSLRHTHGAGTSTNELVNGSNCSASGDYICDTAADPRLGYSNVSSSCVYTGTSTDANNDTYAPDPNNVMSYSRKQCRTLFTQQQYARIQATYQTSRSNLTCPSFNIAFDSDLSMDCSNSLTVNFSDDGVGATAWEWDVNGDGTIDYTTQNPEHTYDAAGKYDVALTISNEQSTTITMTKPEFINVGVNQFETSSIELSLTTDNFPEETTWNFKDGDGNILYSGGPYIEGQDENTIFTQVMNINGSGCYSFEIEDSFGDGICCSEGSGSYELKDTTGNVIISGADYGSGEVTLLSNAVLSTQSFFTTNHIAVFPNPASSVLNVKLSDQTELPDAFKIYNILGQTVLQKAVRSNADLKIDISSLSNGMYFIKLSQSDRLISIPFVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKM7</accession>
    <name>A0A5C6ZKM7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">STAS/SEC14 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_04090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038396">
        <property type="entry name" value="SpoIIAA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="108" mass="12015" checksum="2A98B0658635CF74" modified="2019-11-13" version="1">MFIIAKDLPKNSIGIKASGETTALNYDGINPVLEIRDEFNRKAKLFIEISDFDASASQFFEDVKSSFNHLDDICAMAVVADKIGLHKDSDLFSFLFPGLLIKEFGAHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKU6</accession>
    <name>A0A5C6ZKU6_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein-export membrane protein SecG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">secG</name>
        <name evidence="11" type="ORF">ESY86_05720</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in protein export. Participates in an early event of protein translocation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the SecG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015450">
        <property type="term" value="F:protein-transporting ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004692">
        <property type="entry name" value="SecG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34182">
        <property type="entry name" value="PTHR34182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03840">
        <property type="entry name" value="SecG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01651">
        <property type="entry name" value="SECGEXPORT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00810">
        <property type="entry name" value="secG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="58"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="92"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD90235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="119" mass="12160" checksum="5927891B9DA15608" modified="2019-11-13" version="1">MSTFTIFLILIILVSFLLVVVVMVQNPKGGGLSSSFGGGGTQQMGGVKKTTDFLDKSTWALATLLLALILISNFAIPGAGGNTESKIISGEQTIESAPATPMATPAQADDTATPADSTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKW0</accession>
    <name>A0A5C6ZKW0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022932607" evidence="1">
        <location>
            <begin position="19"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="136" mass="16033" checksum="03B2DB0A1EF35F75" modified="2019-11-13" version="1">MKKIFLLVVLSMSLFACSLDDDTPNFYQEILPIESVTIPEEFEFGGIYEISMTYFRPSSCHVFHNFYYEINENERTVAIINNVYTEQNCEELEDEEVEVSFNFEVTRTDPYVFRFYQGTDESGDDTYYIVEVPVVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKZ6</accession>
    <name>A0A5C6ZKZ6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha-amlyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_02885</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aamy" evidence="1">
        <location>
            <begin position="52"/>
            <end position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="563" mass="63150" checksum="73BB20739C684309" modified="2019-11-13" version="1">MKKLILLTLIATSLSCKNSVSDAEKEMKETSKEKTTASLETPFIWEAANLYFLMTDRFNNADPSNDVNFGRDKKTAKLRGFEGGDIKGVTQKIEDGYFSDLGINAIWLTPVVEQIHGGTDEGTGTTYAFHGYWTKDWTALDPNFGTKADLKALVDAAHKKGIRIVLDAVLNHTGPVTAKDPVWPDAWVRTGPTCTYEDYESTVACTLVDNLPDIRTESDEAVELPPQLVQKWKDEGRYDEEIAELDAFFEKTGHPRAPRFYIMKWLADYITDFGIDGYRVDTVKHTEESVWQEFRSISDAAFAEFKANNPEKVLDDNGFYMVGEVYNYGISAEKAFDFGDKKVNYFDKAFNSIINFELKYDAAKQTKEAIFKRYSKVLNGDMQGYGVLNYLSSHDDGSPFDAKRENPYETATILMLTPGAAQVFYGDESARILEVEGTEGDAKLRSNMNWEAIKNDAKTQKILAHWQKLGTFRSEHPAIGAGVHQMITQKPYVFYRSFSKGDFKDLVVVGLDLKAGSKTLKVSSVFEDGTLLHDAYSGQDVAVKNGNVSINSEFSIVMLELKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL31</accession>
    <name>A0A5C6ZL31_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hotdog fold thioesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_01905</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003736">
        <property type="entry name" value="PAAI_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00369">
        <property type="entry name" value="unchar_dom_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4HBT" evidence="1">
        <location>
            <begin position="48"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="136" mass="15065" checksum="C93A67FD7ECDC83D" modified="2019-11-13" version="1">MPINESNISHKMLSQDAFSSWLGIQILESEIGRCKVGMTIRKDMLNSMGKAHGGISYALADTACGFAANSHGKYAVSIETSINHIEALEEGDYLVAESVIEKVKNKLGFNIVEVKRDNELVALFKGIVYRTNKEWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLH3</accession>
    <name>A0A5C6ZLH3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_01755</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023026894" evidence="1">
        <location>
            <begin position="23"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="256" mass="28618" checksum="462C32913797D997" modified="2019-11-13" version="1">MNRFLTLLVVSLSLLFTSCEFSEDVYINEDGSGSMTFSVDASAIMEMAANMGAEGEKKGLDKTMDSTIVLKQLLEEKKDSISKLPTEDQEKLKALEDFKMHISINPETKKMLFDMSTEFKKIGEIQKMFKGLNAMSSMNTEVNQDGNGAGSPFNTLGGDASTEVSYAFDGKTFKRSAKIVDQQKHQQAMDSLGDSAMMFGSSRYKLNYHFPRAIKSVSKEDVTFSEDRKTVIMDLSFMSVLRTPEILDFEVVLEDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLL2</accession>
    <name>A0A5C6ZLL2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">CusA/CzcA family heavy metal efflux RND transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_05070</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2090.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027463">
        <property type="entry name" value="AcrB_DN_DC_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004763">
        <property type="entry name" value="CzcA/CusA/SilA/NccA/HelA/CnrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32063">
        <property type="entry name" value="PTHR32063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00873">
        <property type="entry name" value="ACR_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82714">
        <property type="entry name" value="SSF82714"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00914">
        <property type="entry name" value="2A0601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="340"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="366"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="392"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="452"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="484"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="542"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="878"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="904"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="929"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="977"/>
            <end position="996"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="1008"/>
            <end position="1034"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="1046"/>
            <end position="1063"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1437" mass="159253" checksum="FAA7FA2901DBD6A6" modified="2019-11-13" version="1">MLRKIIQFSLKNKLIILLLIAFVVGFGIYSLTRISIGAVPDITNNQVQVITTSRNLSTQDVEQFITYPVELEMANLPGVKEIRSVSKFGLSVVTIVFDEDLGTYLPRQLIAEKIKSASEKIPEGFGSPEMGPITTGLGEIYQYILDVRPGFEDRYTVTELRTIQDWVVKRQLSGIPGVVEVNTWGGFLKQYEVAINPQKLKAMNIAILDIYTALQKNNSVAGGGYIEKTNKAFFIRGEGLISSLEDIENIVVKNEGLPIYIKDIANVGFGSATRFGAITGNGQGEKVLGQVMMLKDANSKEVIDAVKERVATIQSALPEGVYINAFLERSELIGKTTFTVAENLILGSLIVIFVVVVLLGNLRSGLVVASVIPLSLLFAISMMNIFEIDANLMSMGAIDFGIIIDGAVIIVEFIAFQITAQVTKIKSLSKEDRQEKVDAITLNSASTMMNSAIFGQLIILIVFIPILSLSGVEGKMFRPMALTFSFALIGAMLFCLTYVPVISSLVLKPSKQGDKNISVRLMKFLNKGYKPIINWALGNKKTVISLSILLLATSFWIFSRMGGEFVPTLDEGVFVIQPILKTGTSLSKTIEITTKIERVLLDKFPEVDQVVSRIGAAEVPTDPMSMEESDVIIKLKPKKEWTSAESKNELAAKFKEALTVIPGMEVEFTQPIEMRFNELITGVRADVAIKIFGQDLSVLASKADEIKNLIEHVEGAADISVEKVEGLPQMSVTYNRSKIARYGLNIADLNQVISMGFAGGTVGSIFEGEKRFDLVIRLDEAHRKNLESLQNLYIDTPNGTKIPMSELAEIKYTTAPAKISRDDTKRRIVVGINVRNRDLQSVVDDVQAIIESKVKLPTGYTISYGGQFENLQSAKARLLVAVPVALVLIFILLYFAFGSVKEALMVYSAIPLSAVGGILLLWLRDLPFSISAGVGFIALFGIAVLNGIVLIEHFKELKERGFANIEERIKKGTSERLRPVILTAAAAALGFLPMAISTSAGAEVQRPLATVVIGGLVTATILTLVVLPVLYAWFEEKAALKMNKKGMVSIALILLSFTMSAQGKALTVDEALQLAIKNNAGLKASSLKIDESNALIGSAFSFDKTAVYYSYDENNLAINGEPLNVFGISQDFKFPTVYFAEKNVNKAQTKMQQSNYDIGLQTLKRDVFLAYYDLSYAKNKARSFQYLDSLYQNFAKAAERRFELGETNYLEMITAKSKQKQLHTLYKQAEQEIILIREQLKKVVQIDRVAVIEEPLKKLELEAISTEANVGLLYFEDSKNYYETLYRKERQNLLPDLSVEYFQGSNSDLNATIKGYLFGLKIPLFFSGNTSKIKASKIAQDIVEEQQQDYKVQLNAKYNTLLAKLQQYNEAISYYEIQGKALSEEIIKTAERSYKEGEIDFFQYIQSMETATDIELTYLENLNKYNQTVIAINYLTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLY8</accession>
    <name>A0A5C6ZLY8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF3857 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_01785</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024618">
        <property type="entry name" value="DUF3857"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002931">
        <property type="entry name" value="Transglutaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12969">
        <property type="entry name" value="DUF3857"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01841">
        <property type="entry name" value="Transglut_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022855183" evidence="1">
        <location>
            <begin position="21"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3857" evidence="3">
        <location>
            <begin position="58"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="TGc" evidence="2">
        <location>
            <begin position="279"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD90718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="639" mass="73084" checksum="DDE4F13D39B3114E" modified="2019-11-13" version="1">MLTKYSLLLCLVFASFYSMAQDKALLQSFSIPSELKQNANAVIRLNEVKVNLRASDEMIINVKRIITVLNKNGDRHVDAFVHYDDDLEINDLEVLIYDAFGKEINKIKTRDFNDVSAVDGGTLYGDSRVKYLEYTAITYPYTVELTYETETKNTAFIPWFYPLADYHLSVEKSTYSLSNPSQLAIRYKILNAEAHAFTEHHEDASYNFSVEHIEAIRPEDHSPLLADLVPKIMFATKTFNLKGVAGSVENWSDFGKWMYKDLLDGTHELPEKTILEVNALIENVTDPIEKAKKVYEYVQNKTRYISVQVGIGGWKPFSAAEVDRLSYGDCKALTNYTMALLNVVGVTSYYTVVFAGNSQKNIQDDFASLQGNHVILNIPNEDETIWLECTSQKLPFGFIGDFTDDRDVLVVTPSGGEIQHTKKYTAKENTQTTKSTCKIFQDGSIDVSLNSVSRGIQYDKKYLLASSTERELEKAYKARWSYINNMSIEAVEIGNDKQSVTFTEDLSFKATNYGNLSGERMLVVVNAVNRFDYVPDRYRNRMLPLKLKRGFKDVDEIELHLPKGYTIEALPKDENLSTKFGSYKRKIVKVNDSTLLYKREFTRNDGDFPKEDYKEFRNFYKEITNQDHAKMALIKTNQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLZ5</accession>
    <name>A0A5C6ZLZ5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Carboxypeptidase-like regulatory domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_05975</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="269" mass="30440" checksum="C5955B3CCA6219E0" modified="2019-11-13" version="1">MKVSKVIAISFFVLKVLLLGAQSVELRGRISANAELEGIYVLNITAQKFTVSNSDGSFKLPISLGDDILVSSVQYEPVTLKVDQQMMNSRFLELELKDRINALDEVIVGKILTGNLISDIENSDAERDINFYDVGIPGYTGKRKTQTERRLYEADNGDFVALYVTPIGPGLAINLHKILNRISGRTKEMKNRVRVEAQELCMTRVQSDFSDILFGEHDIEERLKFEFFFYVSEDPNFLALCDTNNGMAMFEFLTQKLLVFAKDDELVKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM11</accession>
    <name>A0A5C6ZM11_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_02990</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="801" mass="91397" checksum="C51D74F32F3E4395" modified="2019-11-13" version="1">MQSVYKRYLESFKQISFFIFLSSTPFLAVSQEQADAYLFNSFKNYTKLPREVAFSHLNKSTLITGETLGFTVYIFDKYFKKPSAVTTNLYCSIENQSGDIIKKSLLLVKNGVAHGSFEIDSLFKSGNFVFKSYTNWMKNFEEQNFYVQNIKVINPEDHDPKSDLKLRDKIDAQFLPEGGHFIANIENSMGVVVKNNLGYGIPNLAGMIYDNNGTEITNFKTNAFGLAKFNITPTDQTRYTVRFENSANEEVMLNPAEAKGLSLKLTDLNDRIAVSLKTNTSTLAEIKQKLFKLSIHNGNQLKVIDVKFEDRLEVLKLIRYEDLYKGINILTVFNEKNQPLLERLFFKYNGIDLIRPSAVKLKKERDSVSITIPFETAIDTSKFNNLSVSVLPAKTKSYNVHQNIISKTYLQPYVQGFVENAMYYFTKIDLQKKSELDLLLVTQGWSSYDWTTVFNKAPENRFAFESGIEFIANIQNSKAVKIVVHPMINSSTIMLDIEPDQENFEVKGLYPEDAEPIRIGAFNKRNKTISSNLYLQFSPSKIPTLDKDIKSFPTTNIVPFDNTRSEINLMASAQNPEILDEVLITAKVEEERLEKISRRHKGRADIFDDIQRYAYPDFASYINSKGFVVNQDANNFYITVPRAITLQDEIEPRTPLVYLDNLLLYDFDILLNFDMTAVDYIIIDKSGLGEGMRGAAGVIKIFTDPLLRIINTDADNVSQLIDIPLTFTSPKTFYSPKYTNYKSDFYQSYGVIDWKPNLKVDHNGNASFKIFDTGNENLKLFIEGTANDGSFISEELTIDMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM78</accession>
    <name>A0A5C6ZM78_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00835</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="111" mass="12587" checksum="206D1188DE7AB528" modified="2019-11-13" version="1">MEQQKLSPVLVYVLAILGLLCCCLGGIGFIFAGIALIIAMNKLKEAQADPELYDPASVKQMNTAKLVAMIILIINVVYLLYTAYRIYTIGWDEIMLQWEDMMEQIQQQQNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM94</accession>
    <name>A0A5C6ZM94_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">L-histidine N(Alpha)-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_02910</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019257">
        <property type="entry name" value="MeTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017804">
        <property type="entry name" value="MeTrfase_EgtD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10017">
        <property type="entry name" value="Methyltransf_33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018005">
        <property type="entry name" value="UCP018005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransf_33" evidence="3">
        <location>
            <begin position="5"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD90922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="312" mass="36176" checksum="69407F42FF83CA8E" modified="2019-11-13" version="1">MNNNFAKDIAEGLTSEEKHLPSKYFYDDNGSRIFQEIMKMPEYYPTDSEFEILSLQAKQIVEQLQFDQAFNIIELGAGDGFKTFKLLEYLVAAKIDFDYMPIDISQEANDLLHAKLKERLPNLSVIPKTGDYFKELKKIGKQERPNLLLFLGGNIGNYLDADAEALLLLFNKYMHAGDKLLIGIDLKKNPLTIFKAYFDDAGISKRFNINLLIRINRELNADFKIDDFDFYCHYDPMSGDVKSYLVSLKAQTVQLKALDMSIDFKQNELIWTELSKKYTIPQIEALAARTNFKAKHHFLDCKYYFTDSLWQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMH8</accession>
    <name>A0A5C6ZMH8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable transcriptional regulatory protein ESY86_03860</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_03860</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the TACO1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.980">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00693">
        <property type="entry name" value="Transcrip_reg_TACO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017856">
        <property type="entry name" value="Integrase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002876">
        <property type="entry name" value="Transcrip_reg_TACO1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026564">
        <property type="entry name" value="Transcrip_reg_TACO1-like_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029072">
        <property type="entry name" value="YebC-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12532">
        <property type="entry name" value="PTHR12532"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01709">
        <property type="entry name" value="Transcrip_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75625">
        <property type="entry name" value="SSF75625"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01033">
        <property type="entry name" value="TIGR01033"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 4" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="240" mass="26883" checksum="01D8EE6D2A04DB49" modified="2019-11-13" version="1">MGRAFEFRKARKMKRWSAMSKAFTRIGKDIVMAVKEGGPDPDANSRLRAVIQNAKSVNMPKDTIDRAIKRASDKSQGDYKEVVFEGYAPHGIAILVETATDNNTRTVANVRACFNKCDGSMGVSGSVVFMFDHSCNFRIHAEGLDPEELELEFIDFGAEEVFADDDGILIYAPFESFGAIQSELESREIEILSSGFEYIPQVTKSLSAEEIVDVEKLLERLEEDDDVQNVYHTMEESSEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMI3</accession>
    <name>A0A5C6ZMI3_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Type I restriction enzyme endonuclease subunit</fullName>
            <shortName evidence="10">R protein</shortName>
            <ecNumber evidence="10">3.1.21.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">ESY86_04410</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Subunit R is required for both nuclease and ATPase activities, but not for modification.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Endonucleolytic cleavage of DNA to give random double-stranded fragments with terminal 5'-phosphates, ATP is simultaneously hydrolyzed.</text>
            <dbReference type="EC" id="3.1.21.3"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">The type I restriction/modification system is composed of three polypeptides R, M and S.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the HsdR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.21.3" evidence="10"/>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009035">
        <property type="term" value="F:type I site-specific deoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007409">
        <property type="entry name" value="Restrct_endonuc_type1_HsdR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004473">
        <property type="entry name" value="Restrct_endonuc_typeI_HsdR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040980">
        <property type="entry name" value="SWI2_SNF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021810">
        <property type="entry name" value="T1RH-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11867">
        <property type="entry name" value="DUF3387"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04313">
        <property type="entry name" value="HSDR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18766">
        <property type="entry name" value="SWI2_SNF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00348">
        <property type="entry name" value="hsdR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 12" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0680">Restriction system</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="11">
        <location>
            <begin position="301"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TXD90617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1039" mass="119499" checksum="15F365F18651A00F" modified="2019-11-13" version="1">MVANYKEYNDSQKPALDLLQKMGWQFLSSEQVFEARGDMYTNVILDDILAQQLSKINAFDYKGASYKFSTGSIQGAINALKNVPNEGLVQTNERVYDLITLGKSFNETVQGDRKAYTVNYIDWKNPENNVFHVTEEFEVEGGKGKRRPDLVLFVNGIPFVVIENKRRDKNDSIDEAISQNLRNQREKEGIPKLFYYAQLLLAVHPNEVKYGATGTAAKFWSFWKEDVEKEVTKLLKKKINQTPSEDRLVTEQDKGLYSLCSPKRLLDLTYKYIVFDGPDKKICRYQQYFAVQDTIQRVKSRNKEGNRQGGVIWHTTGSGKSLTMVMLSKALALDTTIESPRIIIVTDRISLDKQIFKTFVNCGKHLKKAKSGNDLIELLQDKGNEIITTIIDKFEIATKRASLKDESKNIFVLVDESHRSQYGSAHANMKRIVPNASYIGFTGTPLMKSQKSTSKKFGGFIHKYTIDQAVKDGAVLPLLYEGRSAKLSINKKQIDKGFERLAAPLSEEAQKDLKKKFATIAKIYESDNVIEEIAFDISKHFSENWKGTGFKAQLAVPKIDTAIKYQKYFEAQSNESLKINTRVVFTPPDSRQNNDDVWSDSTSESRKYWEKILERFNDQEAYETYVIDRFKESSNEVEIIIVVSKLLTGFDAPRNTVLYLAKPLVAHNLLQAIARVNRLFSGKEYGHIIDYVGVLGKLDEALTEYSALEDFDEEDLKNTVVDIKDEIRKLPVRHAEVWDIFKEVYNKSDIEALERHISEKDLRDQFYDRVSAFARLLQTALASDDFYSEFNTEQIGFYKNELKKFQSLRLSVQFRYAEKISYKEYEPRVRKLLDTYIDADEVQVLARDVNIFDKNMVEEALETYGKTAASKADFIANQMKRVITENMEKDEAFYKKFSQLIEDTINDFYDGRITEKEYLEAMQKTREDLANGYQEGIPEGLQDNPRARAFYGALNEVLIKKLDKEISKKKVAKAGLEIEAIVNNLIITDWKKNVDIQNKMENEIEDYLIGKRTQFGIEISFDEIDSILIKCLRVAKNNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMK5</accession>
    <name>A0A5C6ZMK5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">TIGR02757 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_00215</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014127">
        <property type="entry name" value="CHP02757"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09674">
        <property type="entry name" value="DUF2400"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02757">
        <property type="entry name" value="TIGR02757"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="254" mass="29407" checksum="9D3C976F7278CC56" modified="2019-11-13" version="1">MNKKDLKEFLDTKAEFYNHPQFIESDPIQIPHQFTLKEDVEIAAFLTATISWGNRKSIINNAHKMMDLLHNSPYDFVMNHSEADLEPLSAFVHRTFNGHDFVQFIKSLQHIYKNHRGLEAVFAANVDRNSLQPAIHQFKNSFFEIDHLPRTKKHVSDPLKNSAAKRINMFLRWMVRNDNNGVDLGIWQSISPSALSCPLDVHSGNVARKLRLLKRKQNDAKALLELDMALRRLDQHDPVKYDFALFGLGVFENF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMN1</accession>
    <name>A0A5C6ZMN1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RidA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00385</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RutC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006056">
        <property type="entry name" value="RidA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11803">
        <property type="entry name" value="PTHR11803"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="SSF55298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00004">
        <property type="entry name" value="TIGR00004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="126" mass="13445" checksum="EBED103670155A49" modified="2019-11-13" version="1">MKTIINTANAPAPIGPYNQAVLSGNTLYTSGQIAIDASTGDLVMDSIEAETEQVMKNLKAVLEAAGMTFENVVKTSIFISDMHNFSKINAVYANYFSADTAPARETVEVANLPKFVNVEISAIAVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMV7</accession>
    <name>A0A5C6ZMV7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TlpA family protein disulfide reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_01470</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13905">
        <property type="entry name" value="Thioredoxin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="314"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="459" mass="51743" checksum="804B7733F9EB743F" modified="2019-11-13" version="1">MKKLLLALCALSIVACQKDTKVDYALLTGSIKNTKAQKASLNAGDYNAEIKLAADGTFADTLRIPESGFYTLTIGREFTPMYLSKGDSVNVVIDATKFDESITYTGNGANENNYLAKKSLNDQSVMENSVEFYSLEEEGFKNKLAEMKKGHEATLQGLKDVDTDFLETEKQNLVYDQYALLQSYKQSHAYYTKKQRFEVSDEFFPEALKNMSYNDPKAYRNSKSYQQMAFKATMDNMFETIGNDIASVSAEDLKVIKDIEIQALKNDVISYLGGFLITAGNENMKGIYEMFIENTTDEKIKTSLTETFDLNKILVKGNPSPQFVNYENHKGGETSLSDLKGKYVYVDVWATWCAPCKREIPFLKEVEKKFQGQNVEFVSTSIDQAKDHAAWNKMVTDMELGGMQLFADNNWNSKFIKDYGIKGIPRFILIDPQGNIVSADAPRPSDPKLTELLESELKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN86</accession>
    <name>A0A5C6ZN86_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">4Fe-4S dicluster domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_00365</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036197">
        <property type="entry name" value="NarG-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13183">
        <property type="entry name" value="Fer4_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103501">
        <property type="entry name" value="SSF103501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="65"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="154"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="207"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="295"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="359"/>
            <end position="389"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD91085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="436" mass="49368" checksum="44A734BED2CF120A" modified="2019-11-13" version="1">MMYLPQILFAIVLLASIGYFARNVSKLRRNITLGHDVDVSDNTSQRWKNMAMIALGQSKMVKRPIAGALHVIVYVGFVVINIEVLEIIIDGLAGTHRIFSPIGATYGVLIGIFEILAVLVFVAVVVFWLRRNTLKLKRFWANEMKGWPKDDANYILYFEMVLMGLFLTMNATDLEFQAMNSGNVISQFIAPWFSSFSESSIHIIERSAWWLHIVGILIFLNYLYFSKHLHILLAFPNTYYGRIKPQGQFENLEAVTSEVKMMMDPDADPYAAPEAGAEDEVPAKFGASDVQDLSWVNLLSAYTCTECGRCTSECPANQTGKKLSPRKIMMDTRDRLVEVGKNIDANNGEFKDDGKQLLDDYITKEELWACTSCNACVEACPVSIDPLNIIMQMRQYLVMEQSAAPMELNNMMTNIENNGAPWPYNQMDRLNWKNEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNB4</accession>
    <name>A0A5C6ZNB4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">S-adenosylmethionine synthase</fullName>
            <shortName evidence="11">AdoMet synthase</shortName>
            <ecNumber evidence="11">2.5.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">MAT</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Methionine adenosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">metK</name>
        <name evidence="17" type="ORF">ESY86_02315</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + H2O + L-methionine = diphosphate + phosphate + S-adenosyl-L-methionine</text>
            <dbReference type="Rhea" id="RHEA:21080"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="2.5.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="11">Binds 1 potassium ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="11">Binds 2 divalent ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Amino-acid biosynthesis; S-adenosyl-L-methionine biosynthesis; S-adenosyl-L-methionine from L-methionine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homotetramer; dimer of dimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11 12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11 13">Belongs to the AdoMet synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.6" evidence="11"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00315">
        <property type="reaction ID" value="UER00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004478">
        <property type="term" value="F:methionine adenosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006556">
        <property type="term" value="P:S-adenosylmethionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00086">
        <property type="entry name" value="S_AdoMet_synth1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022631">
        <property type="entry name" value="ADOMET_SYNTHASE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022630">
        <property type="entry name" value="S-AdoMet_synt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022629">
        <property type="entry name" value="S-AdoMet_synt_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022628">
        <property type="entry name" value="S-AdoMet_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002133">
        <property type="entry name" value="S-AdoMet_synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022636">
        <property type="entry name" value="S-AdoMet_synthetase_sfam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11964">
        <property type="entry name" value="PTHR11964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02773">
        <property type="entry name" value="S-AdoMet_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02772">
        <property type="entry name" value="S-AdoMet_synt_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00438">
        <property type="entry name" value="S-AdoMet_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000497">
        <property type="entry name" value="MAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55973">
        <property type="entry name" value="SSF55973"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01034">
        <property type="entry name" value="metK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00376">
        <property type="entry name" value="ADOMET_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00377">
        <property type="entry name" value="ADOMET_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 11 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 11 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 11" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="10 11 12" id="KW-0630">Potassium</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="S-AdoMet_synt_N" evidence="14">
        <location>
            <begin position="2"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="S-AdoMet_synt_M" evidence="15">
        <location>
            <begin position="113"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="S-AdoMet_synt_C" evidence="16">
        <location>
            <begin position="244"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Flexible loop" evidence="11">
        <location>
            <begin position="98"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="42"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="164"/>
            <end position="166"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="241"/>
            <end position="242"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="250"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="256"/>
            <end position="257"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="273"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <note>ligand shared between two neighboring subunits</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="277"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <note>ligand shared between two neighboring subunits</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="281"/>
        </location>
        <ligand>
            <name>L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="TXD90814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="417" mass="46093" checksum="C964CD88876E04D4" modified="2019-11-13" version="1">MSYLFTSESVSEGHPDKVADQISDALIDNFLAFDPESKVACETLVTTGQVFLAGEVKSKTYLDVQKIARDTINKIGYTKGAYMFDGSSCGVLSAIHEQSEDINRGVDKANKEEQGAGDQGMMFGYATRETENYMPLALDLSHRILKELAVLRREEKDITYLRPDSKSQVTIEYSDDNSPQRIDSIVVSTQHDDFADDETMLAKIRKDIIEILIPRVVAKLPEQLQELFNDDITYHINPTGKFVIGGPHGDTGLTGRKIIVDTYGGKGAHGGGAFSGKDPSKVDRSAAYATRHIAKNMVAAGVCDEILVQVSYAIGVVEPTSIFVETYGTCPFNITDGEIAQKVRSLFDMRPAAIEKRLRLRQPMYSETAAYGHMGRTSETVSKTFEQFNGESVTLDVELFTWEKLDYVDEIKAAFGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNC8</accession>
    <name>A0A5C6ZNC8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">SDR family oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_00605</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="293" mass="31936" checksum="2A80AA58E289AC1B" modified="2019-11-13" version="1">MNYTNKMLRDDALKGKTIVVTGGGSGLGKAMSKYFMELGAQVAITSRDLDKLKNTASALEKETGGSCLPVQCDVRHYDQVEAMHDAVIAKFGKVDVLLNNAAGNFISPTERLSANAFDVIIDIVLKGSKNCSLAFGKHWIDSKQENTSVLNIVTTYAWTGSGYVVPSAAAKAGVLAMTRSLAVEWAKYGMRFNAIAPGPFPTKGAWDRLMPGNLQEKFDMAKKVPLNRVGEHQELANLAAYLVSDFSAYINGEVITIDGGEWLQGAGQFNMLSEISEDQWDQLEAMIRKKKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNL8</accession>
    <name>A0A5C6ZNL8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glycoside hydrolase family 65 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_02865</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 65 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005194">
        <property type="entry name" value="Glyco_hydro_65_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005195">
        <property type="entry name" value="Glyco_hydro_65_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005196">
        <property type="entry name" value="Glyco_hydro_65_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037018">
        <property type="entry name" value="Glyco_hydro_65_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017045">
        <property type="entry name" value="Malt_Pase/Glycosyl_Hdrlase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03633">
        <property type="entry name" value="Glyco_hydro_65C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03632">
        <property type="entry name" value="Glyco_hydro_65m"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03636">
        <property type="entry name" value="Glyco_hydro_65N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036289">
        <property type="entry name" value="Glycosyl_hydrolase_malt_phosph"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_65N" evidence="6">
        <location>
            <begin position="15"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_65m" evidence="4">
        <location>
            <begin position="324"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_65C" evidence="5">
        <location>
            <begin position="710"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="359"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="602"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR036289-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR036289-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03633"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD90914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="768" mass="88442" checksum="ACCAF190AD270C1F" modified="2019-11-13" version="1">MNHNYIKPNPWSIIEEGFDAERVKSSESLMSLGNGAMGQRANFEETYTGKTFQGSYVAGVYYPDKTRVGWWKNGYPEYFAKVLNAPNWIGINVNINGEALDLAKCNKVEHFRRELNMKEGWLSRSFTATLQNFVEIKVEVKRFLSLEMDELGAIEYKITPINNAAQIDFMPYLDNGITNEDTNWDDKFWDVLSVDHEGEQAFITSRTMKTHFYVCTAMQTQVSMNGSKIASEKTVNATNDKIEFTYKNEVSKGDSITMTKFGGYTVDRNHDKNDLVSVAKNTLQKACDLGFEALLQQQKQAWAKIWDMSDISIEGDVAAQQGIRFNIFHLNQTYSGKDARLNIGPKGFTGEKYGGSTYWDTEAYCIPFYMATKDHEVARNLLTYRYNHLEKAIENAEKLGFSNGAALYPMVTMNGEESHNEWEITFEEIHRNGAIAFAIFNYFRYTGDFSYIPEKGLEVLIAIARFWQQRATCSSQKNQYMILGVTGPNEYENNVNNNFYTNYIAKWCINYTLEMITKVKEGFSEDFARIKGKTKITDNELDLWKKVADDMYFPFSEAHNIYLQQDGFLDKELITVADLPKSQRPINQKWSWDRILRSPYIKQADTLQGFYFFEDHFSTEELERHFDFYEPFTVHESSLSPCVHSIQAAKLNRMEQAYEFYLRTSRLDLDDYNKEVEEGLHITSMAGTWMSVVEGFGGMRVKNDVLSFEPKIPKGWDSYAFKINFRNQILKIDVAQNGTSFKLEGDSDLTIMVNGKLVEISPNELVTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZP69</accession>
    <name>A0A5C6ZP69_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Uridine kinase</fullName>
            <ecNumber evidence="4">2.7.1.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_00575</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>ATP + cytidine = ADP + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24674"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17562"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.48"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>ATP + uridine = ADP + H(+) + UMP</text>
            <dbReference type="Rhea" id="RHEA:16825"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16704"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.48"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Pyrimidine metabolism; CTP biosynthesis via salvage pathway; CTP from cytidine: step 1/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 4">Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uridine: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the uridine kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.48" evidence="4"/>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00574">
        <property type="reaction ID" value="UER00637"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00579">
        <property type="reaction ID" value="UER00640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004849">
        <property type="term" value="F:uridine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044211">
        <property type="term" value="P:CTP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044206">
        <property type="term" value="P:UMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd02023">
        <property type="entry name" value="UMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006083">
        <property type="entry name" value="PRK/URK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000764">
        <property type="entry name" value="Uridine_kinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00485">
        <property type="entry name" value="PRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00235">
        <property type="entry name" value="udk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PRK" evidence="5">
        <location>
            <begin position="3"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD91121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="204" mass="23644" checksum="F589F258E0121FF7" modified="2019-11-13" version="1">MLIIGIAGGTGCGKTTVVNQILNELPEGEVGILSQDSYYMDTTHLSYEERTKINFDHPRSIDFELLEAHLKALRRGEHVDQPVYSFVKHNRTGDTIKTKPRKVMIVEGILILTHPELRKLFDIKIYVHADSDERLIRRLKRDISERGRDLDEVLARYQNTLKPMHQQFIEPMKEYADIIIPNNRHNMVAIGIVRTIINEKLNYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPD7</accession>
    <name>A0A5C6ZPD7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carboxypeptidase-like regulatory domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_01515</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023027441" evidence="1">
        <location>
            <begin position="19"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="327" mass="37749" checksum="C0C8355D787EE7E0" modified="2019-11-13" version="1">MRIISPLLFLLLTSLTYAQTKVLDRETKYPVSYATISFGDGQGIFADDEGSFYFTKKLYPDVDSLYISALGFKELNIATKDLPKTLFLDAEIDNLDEVVVHAKIDRKFKEESFKPYLDDDYYHCWLPTIESEIAVYFPNPDEKLKKITEVIFPITLESRDWSKRNKSNADKRPFSTLFKVKFYRNNAGVPGEVLTYDNIVFRATEKNGDSYELNVDENDLYFPKDGFYVSLQVLGYTDEKGKLLPNKKYKEIKAKNGRGTVKIPTNFRPLLPFTDEMDAHRTYIKRVFISGNNWVQFKQGNGIESSLLKSNLNNYGVGINYNAYKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPI4</accession>
    <name>A0A5C6ZPI4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_01300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="157" mass="18386" checksum="62383833B50CA5BF" modified="2019-11-13" version="1">MKIIQLFPIVLLLMFSCQDNTKNTTEEDPDTQDKKVNTQLKGAWELVGYYNYVNNKVTDSFKLTEGYKQVKMYTATKVMWSKSVPLDSTEWFGYGSYEIAGNDLTEMLNYGSEMMTKIIQEKREFRYELNLSPNKFSQIELDGDGNRIYSENYVRIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6Z9P9</accession>
    <name>A0A5C6Z9P9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Sel1 repeat family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19995</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000054">
        <property type="protein sequence ID" value="TXD86515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="369" mass="44063" checksum="96115AA23CAE9F10" modified="2019-11-13" version="1">MRNYTLTILFIFSTLIVLAQDKNYEKGLKSFDSKNYLKSFELLKPFADKGDSMAEFVVGFCYFNPELKLKNNSLAEHYLLSSAEKFNTKAMGFLSIFYFQKGIENEEFKVQSLVWAEIAGSYDPVFNGTTTRYLIRNYLNENELKQVEEILLTKKSKFEKISIEAFHSINKQMKNDNENSEKAKIPENKLNLIKNPYSDWVYRWKSEHFECDTMYYTAEIESQIIDSTIINIKNNKSFEIDYLYNGNQSKPFKITADEQNYLISELEKLKNYRWEKDIFPFSKRLEQNEIQETFDNTEKLATEKEKNMCSIVYTFSKPIFFRNNTIALYLNQSRYRTNYTQLDFSFYKFENERWEEIVRVYAYYESAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAV1</accession>
    <name>A0A5C6ZAV1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MerC domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19640</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000044">
        <property type="protein sequence ID" value="TXD86656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015097">
        <property type="term" value="F:mercury ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004891">
        <property type="entry name" value="Mercury-R_MerC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03203">
        <property type="entry name" value="MerC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="127" mass="14415" checksum="977BDC47BA66747A" modified="2019-11-13" version="1">MKLKNQTIDLIALTSSIICAIHCAAIPILLSFSALSSIHFLHNPLIEWSFISLGVILVVVSLWPSYRKIHQRSMPLWLAAIGFVFIGISRLDFSLWWETGNTVFGACLVSYAHYRNWKLLSVKPHLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZB56</accession>
    <name>A0A5C6ZB56_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ATP-binding cassette domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_17530</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000027">
        <property type="protein sequence ID" value="TXD87236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025302">
        <property type="entry name" value="DUF4162"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13732">
        <property type="entry name" value="DUF4162"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="6"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD87236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="309" mass="34835" checksum="D330957FA9A28C9C" modified="2019-11-13" version="1">MTTDLLVADSVSKSYGDFKALNNVSISVPKGSIFGLLGPNGAGKTTLIRIINQITMPDQGRILLDGKPLTPNDIQNIGYLPEERGLYKSMKVGEQVLYLAQLKGMTKQEAKDRLKYWFDKLDIGDWWNKKIQELSKGQAQKIQFIVTVLHQPKLLIFDEPFSGFDPINANLIKDEILQLRDEGATVIFSTHRMESVEELCDHIALIHKSNKVLDGKLTDIKRQFKTNTFEVGLQTDQVQTVTEAIKTRFEVLPATFKNLNDDLKMNVKLNANNSSNDLLHFLTSNAEVHHFVEVIPSASDIFIHTVKNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBH6</accession>
    <name>A0A5C6ZBH6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Polyprenyl synthetase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_19235</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the FPP/GGPP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000038">
        <property type="protein sequence ID" value="TXD86789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00685">
        <property type="entry name" value="Trans_IPPS_HT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000092">
        <property type="entry name" value="Polyprenyl_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033749">
        <property type="entry name" value="Polyprenyl_synt_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00348">
        <property type="entry name" value="polyprenyl_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00723">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00444">
        <property type="entry name" value="POLYPRENYL_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="324" mass="36272" checksum="16046D63F9091D23" modified="2019-11-13" version="1">MQTIESYHDAFVTYLSDFVEPKEPKALYEPIQYILQLGGKRLRPILTLMTTEILGGDYKKAMDAALSVEVFHNFSLVHDDIMDAAPLRRGQETVHTKWDVNTAILSGDAMLIMAYQLFENYEPKTFRDLAKLFSKTALEVCEGQQYDVDFETRDDVTIAEYLKMIEYKTAVLVGAAMQMGAIVANASEACQKAIYDFGKNLGIAFQLQDDYLDAFGDPETFGKQVGGDIIENKKTILYLKALEFSNVSDRRQLEHLYGINPSDPSDKIEAVKQLFVSSAAAEATSQEISRYTEKAFAVLEGIEISEQGKAALKTFGKGLMKRDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBI5</accession>
    <name>A0A5C6ZBI5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RDD family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_19295</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000038">
        <property type="protein sequence ID" value="TXD86799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010432">
        <property type="entry name" value="RDD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06271">
        <property type="entry name" value="RDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="61"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="RDD" evidence="6">
        <location>
            <begin position="15"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD86799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="153" mass="16986" checksum="400528160524E1C9" modified="2019-11-13" version="1">MNESRQTLQIKTEPNIGNRFVAGLVDYIIIYGVTFFLIFTFGEPNDEGGYSLNGLPGLIPIIFWLIMTVGLEIGFGATIGNSLVGLKAIPKNGTNRKLTFGESFKRHLLDPIDMFFFGLIGIITIKNTDKNQRLGDIWGNTIVVKTSELNKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBP8</accession>
    <name>A0A5C6ZBP8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase family 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_16825</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000024">
        <property type="protein sequence ID" value="TXD87443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="236"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="510" mass="59169" checksum="22376E13E59B1832" modified="2019-11-13" version="1">MIVIYHHNNQVHSIVDHKLNAVLPIIEKPILKALMHLASKNDNKILVWCRLDCKALLNLEGITNAFRTKNIMVSYGDGFYLPDAIGYVENSPFINVNTSVKYPTWKMHSAVGAIYSSTLIKFKNCIFSEDFEYDLNSIAKLGMPKGVFCYSEPKLLIKPLAPSAKRVGIFTLFRFVKQHYRTPWVFLLALNFSWHERKWPFLPLLLSLFYKRRHFKDSIPLESIHDDPVSTLPSIDVIIPTIGRSSYLHDVLMDLAKQTHLPHQVIIVEQNPDPESLSALDFIYSEVWPFKIDHHFIHQTGACNARNLALKQVVSEYVYLADDDNKFDGNLIERVLHQMLTFNLDVVSMSYLQKNEVETRKQPIQWATFGAGCSIMKAQYLKEVSFNMSLEFGYGEDVDFGMQLRNLGADVIYLPDISILHLKAPIGGFRSTFKQLWMDDPIQPKPAPTVMLNTIKNKTKWEVLGYKTQLCINYYFVQKVKNPLRYFKMFNKQWERSIYWANQLKRDNRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBV8</accession>
    <name>A0A5C6ZBV8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Lrp/AsnC family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_16575</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000023">
        <property type="protein sequence ID" value="TXD87509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000485">
        <property type="entry name" value="AsnC-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019888">
        <property type="entry name" value="Tscrpt_reg_AsnC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019887">
        <property type="entry name" value="Tscrpt_reg_AsnC/Lrp_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019885">
        <property type="entry name" value="Tscrpt_reg_HTH_AsnC-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01037">
        <property type="entry name" value="AsnC_trans_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00033">
        <property type="entry name" value="HTHASNC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00344">
        <property type="entry name" value="HTH_ASNC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00519">
        <property type="entry name" value="HTH_ASNC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50956">
        <property type="entry name" value="HTH_ASNC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH asnC-type" evidence="4">
        <location>
            <begin position="3"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD87509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="147" mass="16857" checksum="DEA6021A4FD9B25C" modified="2019-11-13" version="1">MHIDNLNWKILKCLQLNARQSNTEIGRTVGISSPAVSERIKKMEEAGVIQNYNTLVSPFEVGYQLKALITLRAFMGMLKPFLEKVKTYDEVINCYRITGNENIVMEVVLKNQKHLEAFIDQLIVYGETKTQIVLSHVIKHNEVKPLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCG7</accession>
    <name>A0A5C6ZCG7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19195</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000037">
        <property type="protein sequence ID" value="TXD86819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011652">
        <property type="entry name" value="MORN_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07661">
        <property type="entry name" value="MORN_2"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="126"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="160"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1119" mass="128837" checksum="99BD6AB08AA07634" modified="2019-11-13" version="1">MFFAMILDFFMIILRTILYCPTNRTPTTMKFRCFVGLVFAITITYGQEQIPYIDYETVFPSVMESVEKEDYDAVIKQLNLINKNDSTYCSVLTSKSYYYILQEKFDDAIATTNEGLSLNCSSQSNLFFFMNKGASYASKKEYTNALDVYETGLELYPRNSKLWFNKGIALENLEQIEGAIDAYQKAIIYNPLYRNAHLRLGDICYKQQLMSQALMCYNMGLILELDTDRAFTLLKQLNEMVADKNSNEPKPGLVVSPDDSAFKNLDLILNNRVALNANYPIDNEIDISLVKQNHALLQQLKSIEANGGFWDAYYLPFFQWISASDHFDDFTYTLSYSIKNEEYQKLVEKKSDEVTAFIEAYVVKWFGLFSQNDKDAAGYLYEDGAFTAEGTWDKEYMVDDWTFYDTDGKLSAKGSYNQKGERIKTWTWFHENGKLKEISRYADGKLNGEHQFFHEDGSPYIRATYKDDAFEGEYTYYLEAGGLKQKKYFHKGELKGKYLAYFDVGESLVEYDADYNAGIIVGDLTEYYADGSVFSVINFKDNKRDGKEIQYYRSGKKSMEADYKAGDLHGSYITFFENGKIREQGQTEAGYYEGNWMSYFSDGTLSSEYAYKNGDFDDLFKSYDTDGVLASEFKYRKGEIIGYKFFDKAGNILSEATKKGGDFFFEGYHPNGNKSAEGNYDISGGKIGDWKFYNYNAVLTDVGHFEEGEPVGSYTTFNAFGEVSQKSEYDKANARQYYQGFYPNGQLQSQGWYKNGLQHGEWHSYFIDGALDAINFYHKDQLHGTQKDFGVDGKLVGHTKFNYGDLVEEVYYDVNEKPYQTFDFDTDKKSYSIVTNYQNGNKQTEITYVNGIKQGPYKHFSVDGKVIISGNYNNDNLNGEWQWYYDDGSLRVTEGYENGNRHGASKRYYQNGQLEDDYFYEHGNTQGSWKSYYGNGELFSVSAHANDLIQGRKEFYSPDGKLQVIRFYSDDVLIGYSYLNSDGTEKEMIPITNETGVLNAFFDNGKASRTTSFVNGKIEGDYMAYYYDGQLENKLHYEKGEQHGKDKKYYPNGQLNYSRSYNYGMLNGPFDTYYPNGKLKESINYLNDEKHGEANYYDETGTLIKTYYYANGDAYDSKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCP0</accession>
    <name>A0A5C6ZCP0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19180</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000037">
        <property type="protein sequence ID" value="TXD86817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="67" mass="7353" checksum="0E662B1CDF4B2ABE" modified="2019-11-13" version="1">MLTLLLLIPILAIGQIPKGHFLDADDSTESGYKSKPFIQDKEGIYHYAVLTALPFDNDCASGLSEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD62</accession>
    <name>A0A5C6ZD62_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytidylate kinase</fullName>
            <shortName evidence="8">CK</shortName>
            <ecNumber evidence="8">2.7.4.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Cytidine monophosphate kinase</fullName>
            <shortName evidence="8">CMP kinase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">cmk</name>
        <name evidence="10" type="ORF">ESY86_17170</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + CMP = ADP + CDP</text>
            <dbReference type="Rhea" id="RHEA:11600"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58069"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.25"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 8">
            <text>ATP + dCMP = ADP + dCDP</text>
            <dbReference type="Rhea" id="RHEA:25094"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57566"/>
            <dbReference type="ChEBI" id="CHEBI:58593"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.25"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the cytidylate kinase family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.25" evidence="8"/>
    <dbReference type="EMBL" id="VORO01000025">
        <property type="protein sequence ID" value="TXD87400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036430">
        <property type="term" value="F:CMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036431">
        <property type="term" value="F:dCMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006220">
        <property type="term" value="P:pyrimidine nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02020">
        <property type="entry name" value="CMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00238">
        <property type="entry name" value="Cytidyl_kinase_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003136">
        <property type="entry name" value="Cytidylate_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011994">
        <property type="entry name" value="Cytidylate_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02224">
        <property type="entry name" value="Cytidylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00017">
        <property type="entry name" value="cmk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cytidylate_kin" evidence="9">
        <location>
            <begin position="7"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="11"/>
            <end position="19"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD87400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="230" mass="25874" checksum="869F3C09D03E5B76" modified="2019-11-13" version="1">MKKIITIAIDGFSSTGKSTVAKRLAKALGYVYVDTGAMYRAVTFYAMQNDLISDDAFDKEGLIAHLDKVKVNFKFNENLGFAEVYLNGTNVEQEVRNMEVSQFVSQVATVSEVRQRLVKQQQAFGKDKGVVMDGRDIGTVVFPDAELKLFMTASAEKRAQRRYDELLERGDKVSYEAVLENVQSRDLVDSTRKDSPLVKAEDAIRVDNSNMTLDEQFEFILKLSEEKISA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDI0</accession>
    <name>A0A5C6ZDI0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_15825</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="146" mass="16662" checksum="989AAA8585E619D1" modified="2019-11-13" version="1">MKTIIAIKNSGNKGKTEIARKLANLLVEVHSDFKPIYPIPFNILKETDFSIVLKIDEKIVGIESQGDPGTNLKTRLETLILEYNCDLIICTCRSRGETVRSISAIANLHKFQTIWDSTYESKICHEEINKLKAEHLYDLMKKLKLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDU2</accession>
    <name>A0A5C6ZDU2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Energy transducer TonB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_15680</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="120"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="293" mass="31333" checksum="20D1D35F15EAAB5E" modified="2019-11-13" version="1">MRYLETKHEQNSAKITALIIVILVLLLFVVGTPYLDPPVEYGVAVNFGNSEVGTGNIQPTEPVKSEPREEVTKPQIKETKVEEAKVEPTKTEAPSEKVLTADNAEAIAIKKQKEAADAKAKADAKAKAEAERVEREKQEAAEKQRQAEEAKKKKLDALIGGVKKSDGTQTGGEGPGDGPGDKGQLDGSPYAPYKGNPGAGNGGMGYGLNGRGKPKFQIFEGCENEYGLIVVDIVVNQNGDVIEATPGVRGSNNATTCLKEVARKIAKSYKWPADSKAPVRQFGKVSINFTPTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDX3</accession>
    <name>A0A5C6ZDX3_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA1(Val) (adenine(37)-N6)-methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.223</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">tRNA m6A37 methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_14065</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>adenosine(37) in tRNA1(Val) + S-adenosyl-L-methionine = H(+) + N(6)-methyladenosine(37) in tRNA1(Val) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:43160"/>
            <dbReference type="Rhea" id="RHEA-COMP:10369"/>
            <dbReference type="Rhea" id="RHEA-COMP:10370"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74449"/>
            <dbReference type="EC" id="2.1.1.223"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the methyltransferase superfamily. tRNA (adenine-N(6)-)-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.223" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016430">
        <property type="term" value="F:tRNA (adenine-N6-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01872">
        <property type="entry name" value="tRNA_methyltr_YfiC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007848">
        <property type="entry name" value="Small_mtfrase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022882">
        <property type="entry name" value="tRNA_adenine-N6_MeTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05175">
        <property type="entry name" value="MTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="1 3 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="MTS" evidence="4">
        <location>
            <begin position="40"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD88220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="244" mass="27526" checksum="A444A0FC69050EEB" modified="2019-11-13" version="1">MKTAFKFKQFSVNQDQCAMKIGTDGVLLGAWATIAHHPFSILDIGAGTGVLGLMLAQRSDAEMIDAIEIDDAAYEQCVDNFESSPWSDRLFCYHAALEEFATETDDTYDLIICNPPFHLATLDCEVSASEKMSKSRETARFQDAMPFEHLLESVATLLSEEGRFCVVIPYSEEEKFKSLAKTFSLFPQKIGRLRGTPSAEIKRSLIDFSFAETLPEISELIIETTRHNYTADYIHLTKDFYLKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE26</accession>
    <name>A0A5C6ZE26_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphoribosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18665</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000033">
        <property type="protein sequence ID" value="TXD86951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="1">
        <location>
            <begin position="5"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="164" mass="18615" checksum="819EEF759A48109A" modified="2019-11-13" version="1">MKNVILNHQEIQNKIRRIAYQIYESNVDENTLILAGIQENGFILAKQIKKQLDVISEIETTLCKVLINKKNPLEAITTSLPPADYQNKSVVLVDDVLNSGSTLIYGVKHFLDVPLKQFKTAVLVDRNHKKFPIKADYKGLSLSTSLHEHVDVNLQTNNFEAFLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE41</accession>
    <name>A0A5C6ZE41_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">FtsX-like permease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_13375</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="296"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="352"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="386"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="435"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="686"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="736"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="770"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="20"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="328"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD88294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="807" mass="88451" checksum="7EBEF2F7DFE62FF7" modified="2019-11-13" version="1">MIRNYFKIAWRSLQKNKLQTFINLLGLTVGTVCCLSILIYVMAQFGYEKQFKNSNSIYRITTTVTSDGIGTQVSAGSSPPIAFALKEDYPEVKEVCRVVYFGEGNNGLLRATGSDKAYYEPRGYIADSTFFKLFNYPFLEGKPEGALNAPNAVVLSKSLAMKIFGNEKALGKTLVLGSGEGQQTLTIKGVFKDDFGKSHLNPNYILTMNSNGVGSFVRSVQNFATQNFALTYVKLITGANVGGLQKKLPVFLQRHGAADLAAVGFEKSLSLQKVSDIHLYSKGIRSQIDKISDINYLYLLLILALFIQLVACINFINLSTARANKRAKEIGVRKAIGADKGDLIRQFLGESVLLSLFASVLSLPLTALALPFVNELTQGAIGYSNIFSWPILVTLLGLGILTGLIAGLYPALILSSIKPVKVLKSSVNLNIGNGYLRKGLVVFQFVVSIGLISSVIIISQQVRHSQKMDMGFNKDNLIAIRLGTETDLRNFNSLATQFSSIKGVAEVSGSNNYPSELILGDLGMHLPGKNPTHLTLVHYTGVSPNYFNTVGTKLLVGRDLRSNDSIQVVVNKATLDAFNIPLDKAIGSILVQANEGSSTNHELVGVAEDYHFASLKEEIAPMLIFNETSPGWIILKANTNNYKNLLNDLERSWKNINANTPFVFNFVDKEVEKLYAEEKRLGKISVVFTSLAILISCLGLFGLVSFVAEQKKKEIGIRKVLGASVQNMVRLLTKDFVRLVGIAFIIAAPLAYVVMQKWLQDFPYRITIEWWVFLIAGGAALLITLLTVSFQAIKAAIANPVKSLRTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE68</accession>
    <name>A0A5C6ZE68_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Response regulator transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_14405</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="10"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="228" mass="26231" checksum="43168B6093749D75" modified="2019-11-13" version="1">MSQLLKTTYNVLIIDDHPAIVDGFKNALNFISAEDYSKQFEVFSASTSEMAYQALEKFPTKRLDLVILDISLPPCEKLKIDSGEDIGELIRLQLPETKIMVCTFHSDRFRLQKIIKRFHPEGFICKQDMDTKDFSTAITNVLLKGIYYSRSIVDVLKQTAFIDIELDKYDFLILKELSNGAKMKELVELLPFTKSAIDKRRCRLKRNLEVQGDSDRDLVLNAKKRGLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEB8</accession>
    <name>A0A5C6ZEB8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Isoprenyl transferase</fullName>
            <ecNumber evidence="2">2.5.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_14670</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="2">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.-" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004659">
        <property type="term" value="F:prenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00475">
        <property type="entry name" value="Cis_IPPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01139">
        <property type="entry name" value="ISPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001441">
        <property type="entry name" value="UPP_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018520">
        <property type="entry name" value="UPP_synth-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036424">
        <property type="entry name" value="UPP_synth-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10291">
        <property type="entry name" value="PTHR10291"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01255">
        <property type="entry name" value="Prenyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64005">
        <property type="entry name" value="SSF64005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00055">
        <property type="entry name" value="uppS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01066">
        <property type="entry name" value="UPP_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2 3" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="22"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="66"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="195"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="21"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="69"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="21"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="26"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="246" mass="28343" checksum="DD3124AD5A5CDB92" modified="2019-11-13" version="1">MDLKSQIQTDKLPKHLAIIMDGNGRWAKQQGFLRIIGHENGTKSVREVVEATAEIGIENLTLYAFSTENWNRPKIEVQTLMKLLVKSLKKEIATLQKNNIKLLAIGCLKDLPKKAHQELLEVIEKTKNNSHMTLTLALSYGSREEIISVVKTLADKVKNNIISIESIDESIINKHLYTQNLPDVDLLIRTSGEHRISNFLLWQIAYAELYFTHILWPDFTKKDLYEALIDYQNRERRFGKTTEQLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZED8</accession>
    <name>A0A5C6ZED8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ROK family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_13535</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01125">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="318" mass="34278" checksum="E81BF613A3D13632" modified="2019-11-13" version="1">MNLAVGIDIGGTKTKIGLVDASGNCLDYLFFRTRDYDDLDAFLDKIKGSIDELIIKQKKPLHLVGCGVGAPNASSRTGTIENAANLKWKGSVPILEKLKQRIDLPMRIMNDASAAALGEMLFGNAQGMTDFISITLGTGLGSGIVANGQLIEGFDGFAGELGHIDMTLGDGRMTGLNVKGGLEAYVSATGLKRTILYMMSKYLDESRFRGIAYNDLHGEDITKAAEEGDPIALKAFDYTAKILGLALANFTAFTQPQAFFLTGGLVNSGKWILEPLERYFEDCLLDVYKGKVQILMSGLPDKTTAICGAAALIWEKQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEF5</accession>
    <name>A0A5C6ZEF5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">50S ribosomal protein L14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 6" type="primary">rplN</name>
        <name evidence="6" type="ORF">ESY86_14880</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 5">Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the universal ribosomal protein uL14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.150.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01367">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036853">
        <property type="entry name" value="Ribosomal_L14_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000218">
        <property type="entry name" value="Ribosomal_L14P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005745">
        <property type="entry name" value="Ribosomal_L14P_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019972">
        <property type="entry name" value="Ribosomal_L14P_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11761">
        <property type="entry name" value="PTHR11761"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00238">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01374">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50193">
        <property type="entry name" value="SSF50193"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01067">
        <property type="entry name" value="rplN_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00049">
        <property type="entry name" value="RIBOSOMAL_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD87951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="122" mass="13413" checksum="163607B368202CE2" modified="2019-11-13" version="1">MVQQESRLKVADNTGAKEVLTIRVLGGTNRRYASIGDKIVVSVKDATPNGNIKKGAVSTAVVVRTRKEVRRPDGSYIRFDDNACVLLNPTGEMRGTRVFGPVARELRDKQFMKIVSLAPEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEM3</accession>
    <name>A0A5C6ZEM3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Metallophosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_13210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="1">
        <location>
            <begin position="99"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="364" mass="41948" checksum="D4DEDA86889C98E6" modified="2019-11-13" version="1">MINRFIMTKVFSLIFICFIGLALVASRTYDYKRVSDISFPKTESFDTIQITDGPYIFITSDSLIEKRIIKGKLETKTAALQTMRSQFDNESSTFTNASKIAALSDIHGQYDVAKTILKNNGIIDAEDNWAYGDGHFVIVGDIFDRGPNVTELLWLIFKLETQAEQAGGKVHYLLGNHEYMVMQNDLRYINKKYRQTERILRTHYDQLYSNETVLGKWLRSKATILKIDNYLFVHAGISLNFIESGIDLEATNQKMRQSLLEEQTETKWDSIYNKYYNSEGPIWYRGYFSEDFKKSQLKKILKTLQVDHIIVGHTSQKQIESLFGNKIFAVDTSIKNGVSGELLFIENGNFYRGTMDGQKIKIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZET0</accession>
    <name>A0A5C6ZET0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">EcsC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_13085</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024787">
        <property type="entry name" value="EcsC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41260">
        <property type="entry name" value="PTHR41260"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12787">
        <property type="entry name" value="EcsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="261" mass="28187" checksum="E31B4F8AD3F9DFD2" modified="2019-11-13" version="1">MHNLGWAIKGVNSLGNVVESKIKYIPEKALNKLQTATQNVLMKIIKANLLTIQKDKAFKKPSNATYRAVVTGSGALSGFFGSTTGIGTAIFVSELGVTTKFLMRTIMDIARSEGEDIYSLEGQLACLQVFALGGESKDDDGVETSYYSTRITLDAGLKTISASGIKMGLETVVKSVGVMGSSTLSNIVAKIASRLSLFMSEKFLAQAIPVLGAVSGGSLNFIFVNHFQKMASAHFTVRRLERKYGVPLVQEVFEKKIEIED</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEX5</accession>
    <name>A0A5C6ZEX5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Anhydro-N-acetylmuramic acid kinase</fullName>
            <ecNumber evidence="1">2.7.1.170</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_15655</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.170" evidence="1"/>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006040">
        <property type="term" value="P:amino sugar metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009254">
        <property type="term" value="P:peptidoglycan turnover"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005338">
        <property type="entry name" value="Anhydro_N_Ac-Mur_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30605">
        <property type="entry name" value="PTHR30605"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03702">
        <property type="entry name" value="AnmK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="353" mass="38836" checksum="76FA1299D812427E" modified="2019-11-13" version="1">MSKSEYKVVGVMSGTSLDGIDLAYVTLSFNERWSFKIHTAETIAYTETWSSILKNLVNLSAEELQTIDKKYTAHLAEAINEFIHKHNITRLDAVCSHGHTALHQPEKQTTYQIGNLPELANLTQQTIVCDFRVADVKRGGQGAPLVPIGDALLFMQYDACVNLGGFANKSSEVNGKRIAYDICPVNIVLNQYAKLLGLDYDAEGAIAKTGFVHKALLAQLNQLPYYKKSAPKSLGLEWVEAQIKPVIAAHPCAVIDVISTFTEHAAMTIAHTIEKGSKVLFTGGGTYNDFLLSRIKTHQDFELVKPANELVDYKEALIFGLLGVLKLRNEVNCLASVTGANQDHSSGQIWFPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF35</accession>
    <name>A0A5C6ZF35_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_13865</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="9"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="252" mass="28074" checksum="CA7412D9AA866EC6" modified="2019-11-13" version="1">MNFIEKHKAIFITALLAGTVVLGLFSFHLTKTTAFLSESFYKMEPQTAQELEKMERIKELEAREQANSGTNEAYNEDKAYEEVMNNFKSMSNDRENVSREVAMPSEASVEDLNDVQTSNSDYNASKSYAIKEQERHSFNKANDILAMHSSEKDKKTSLGNKNSSVSFSLVNRTKVKLPPPVYLCEVSGKIVVNITVDSEGNVTDTYINSSSSSDNKCLVDAALEYAGSALFSKDANNNKQIGSITYYFKGKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF36</accession>
    <name>A0A5C6ZF36_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NifU family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_14035</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001075">
        <property type="entry name" value="NIF_FeS_clus_asmbl_NifU_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01106">
        <property type="entry name" value="NifU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="SSF117916"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NifU" evidence="1">
        <location>
            <begin position="10"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="80" mass="8847" checksum="57730AEBD5EBAB64" modified="2019-11-13" version="1">MNIEELRNNIEKALDEIRPFLQSDGGDISLLSIEDGRIVKVQLQGACVGCSVNQMTLKSGVEMTIKKYAPQIEQVINIEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF76</accession>
    <name>A0A5C6ZF76_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glycoside hydrolase family 97 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_13185</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029483">
        <property type="entry name" value="GH97_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019563">
        <property type="entry name" value="GH97_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029486">
        <property type="entry name" value="GH97_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14509">
        <property type="entry name" value="GH97_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14508">
        <property type="entry name" value="GH97_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10566">
        <property type="entry name" value="Glyco_hydro_97"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023087992" evidence="2">
        <location>
            <begin position="26"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="domain" description="GH97_N" evidence="4">
        <location>
            <begin position="30"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_97" evidence="3">
        <location>
            <begin position="301"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="domain" description="GH97_C" evidence="5">
        <location>
            <begin position="607"/>
            <end position="707"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF14509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD88258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="710" mass="80595" checksum="34DEEFC8FB929964" modified="2019-11-13" version="1">MKKIVNPYYWIVLLIISVSCGTPKADLTANSPDSNIHMEFGLSKSGQPFYLVEHKDKMVIDTSFLGFDFKDVPSLKDNFKLVSSSKATKDETWQLPWGEQLDVRDNYNELVISLEEQSDLKRKMTLHFKVYNDGVGFRYEVPEQNNLKEVLITDENTAFNLTGDHRVWWIPGDWDIYEQLYNETKFSEIDAISKRDHPNLNSTYIPENAVNTPVTMKTDDGLYLSFHEADLTNYAGMTLKVDPQNLNMVSELVGSERLGGKAKLTVPFETPWRTIQIAEKAGDLLESNMLLNLNDPNAIGDVSYFTPMKYVGIWWEMHIGKSTWDMEGSQDMSTYTLGKPGTSTHGATTENAKKYIDFASDNGIKGLLVEGWNTGWDKWINTDDREGVFDFMTPYPDYDFEEVMRYADEKGIEVIMHHETSAAPRTYEKQMDVAYDFMKANGMNSVKTGYVGNIIPKGEYHHGQWMVNHYQHVLEEAAKKKIAVNAHEPIKDTGKRRTYPNAISREGARGQEFNAWATDGGNPPSHLPTVAFTRMLSGPFDFTPGIFNIKFDDYKKENQVNTTLAHQLALYVVIYSPIQMASDLPEHYMVDGKTHPAFQFISDVGVNWQHTKVLDGEVGDFVTIARQERETGNWFVGGITDENERTETLTFDFLETGKTYKATLYKDGPNAHWDDNPQDYAIEELELTKASSLDIKLAPGGGFAMSIVNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF79</accession>
    <name>A0A5C6ZF79_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Porin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12075</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027385">
        <property type="entry name" value="OMP_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13505">
        <property type="entry name" value="OMP_b-brl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="OMP_b-brl" evidence="1">
        <location>
            <begin position="30"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="212" mass="23735" checksum="766246476E25B7CB" modified="2019-11-13" version="1">MRKLCTVLFLVITASIYGQDNEEKFLIETGTWNLEGSFSINSAKSEFFENDNLKSEFFGFSISPKVGYAIQDNLVIGLGLGYSYSESEFGNQQALNSDRNSNSYSIFPYIKKFIPIGKKMAFHLQGETRYSLGSTNFENSGIEERESKSFFIGIRPGVSYFLSKSILLQANFGQLGYENNQIKVGDTDDSETDVFGFDISSSNIIFGLTVLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFB5</accession>
    <name>A0A5C6ZFB5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">BamA/TamA family outer membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_14665</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071709">
        <property type="term" value="P:membrane assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000184">
        <property type="entry name" value="Bac_surfAg_D15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010827">
        <property type="entry name" value="BamA/TamA_POTRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039910">
        <property type="entry name" value="D15-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023707">
        <property type="entry name" value="OM_assembly_BamA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034746">
        <property type="entry name" value="POTRA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12815">
        <property type="entry name" value="PTHR12815"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12815:SF23">
        <property type="entry name" value="PTHR12815:SF23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01103">
        <property type="entry name" value="Omp85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07244">
        <property type="entry name" value="POTRA"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006076">
        <property type="entry name" value="OM_assembly_OMP85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51779">
        <property type="entry name" value="POTRA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1134">Transmembrane beta strand</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022961179" evidence="5">
        <location>
            <begin position="36"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="domain" description="POTRA" evidence="6">
        <location>
            <begin position="206"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="POTRA" evidence="6">
        <location>
            <begin position="296"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD87910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="861" mass="97293" checksum="3BA80FA35F7BB59A" modified="2019-11-13" version="1">MEKQPNNLANILLLKTYFKSLLTVTALLIAFAATAQQSNFNKGKKYILEDVKVTGNTNFSETTIISFSRLKKGEEIVIPGEDISNAIKKLWDSNLFSSIDVYLTKVEGDKAFLEINLFDLPELRDLKIEGVKKGKKEAIIKDNSLSKGIKVTENLITTTRNYLTNKYKKDGFLNTKVRVDTREVTDDSIQKARVDMLVYIDKGEKVKIQNIAIDGNEKLSDKKLKKAMKNTKEKNFFNFLKRSKFIRADFKEDLVNLIDVYKENGYRDARILSDSIAYLDNETIDVHVKLEEGEQYEFGKITFVGNSVYTDQQLQSVLRIRGGSTYNGVELRKRIADDTKPDAADLTNLYQDSGYLFSSINPVEVSAEGNVIDLEIRIVEGKPAYFNAVSVSGNEKTNDHVIYRELRTKPGQLYRKSNVIRTIRELGQLGFFDAQLITPNMKNFNTQDGLVDIEYQVVEKGSSQIELQGGYGGGGFIGTLGLSFNNFALKDIFKKEAYKPIPTGDGQSLALRLQASRFFQTYSFSFSEPWLGGKRPTQLTTSISHTKQFLFNPITRDADKDRRFNITGVSIGIAKRLKEPDDYFQLSQAVSFQHYDLKNYNTGLFTFGNGYSNNLSYTVGLTRNNTATDPIYPTQGSNFSVSAKLSIPYSLFNSTDYGALKEERDELNPQNPDELARIGEIDQERYKWLEFYKVKFKGDWYTNPVDKLVLKSGMEFGFLGAYNQDRGIIPFERFFIGGDGLGNFALDGREIIQLRGYPNQALSSQDGGTIYNKFSLELRYPITLGASAKIYGLTFLEAGNSFDSFRDFDPFRLKRSAGFGLRIFMPAFGLLGIDFGHGFDPLPGGVQKNGWETHFIIGQQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFF2</accession>
    <name>A0A5C6ZFF2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Type IX secretion system sortase PorU</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">porU</name>
        <name evidence="4" type="ORF">ESY86_12615</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029030">
        <property type="entry name" value="Caspase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001769">
        <property type="entry name" value="Gingipain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029031">
        <property type="entry name" value="Gingipain_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01364">
        <property type="entry name" value="Peptidase_C25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52129">
        <property type="entry name" value="SSF52129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022994676" evidence="2">
        <location>
            <begin position="19"/>
            <end position="1284"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_C25" evidence="3">
        <location>
            <begin position="540"/>
            <end position="911"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1284" mass="143370" checksum="BD3B0DC95370A441" modified="2019-11-13" version="1">MKKSLPIFLILCSVLAYAQQKKFEINWQDNKVMETETTKMEVPAFDAAHFSFSEESGLKYFAQWKVPSTINSGSLKLSNLSYSVMSANELKDLPSQTIPGSPNATLRNAVARDNQFAFLEFSPIIKENGIYKKITGFVIDYSYGSNSNLYARNNENIENSVLSSGSWHKFYVDKSGVFKLSKSFLDRIGVNTNVDPRTIKIFGNGGAMLPLINQDFYPLDLTENAIKFVGEEDGTFDTNDYILFYAEGPREYNDESNTNINLFTDKSHYFVNVGAGTGKRIAPLNQPSAAANLTVDTFQDYQFYETDEYNIGKLGRRWFGDRFDVENQREYKFNFPNLVSSEPARVKVLTGAVNEGNINTTMSVVINGQLVNSMTFAPLSAQSNLLGSSRSYSSNIILNAAEVTFNLSYDNAGNPTSVGYLDYISIEATRQLRFEGAQFPFYNKEVSTTSGVVQYNLSNAANVQEIWDITDKYNVASAANLEQTADFSFKETAGSQKKYVIVSNLNYYEPLRDGNSSVANQNLKGTIFNNTQGEFEDVDYLIVTPTILLSQAQRLAQINRDRNNLNVKVVTLDKIYTEFSSGNQDIAAIRNFVRYIYQNASSPANRIKYVCLFGDSSYDYKDRLPNNTNLVPSWHSNNAFSLTNSFVSDDFFGMMDPQEGSMVTSDRLDIAMGRILAETPQRAKDMIDKVETYYAEDSFGSWRNNIVVISDDIDKPGEQNLQLTTDAIADEITTQKPFINDIKIHSDAFQQQATASGERYPAVNKAIKDAIEVGALVVNYFGHGGEDGLAAERIFTKVDAQEIRNICKYHLFVTVTCEYTKFDNPQRLTAGEFTYWNKEGGAIGLITTTRRIFLNTGVDYNVVLEKYLFAYGSNEYPSMAEALRQTKNDNALAGNPQKTLVFYIGDPAMKLAIPKPDIKLSAVNDVPLDQQTEVLEALGRVKMSGKVYDSQGNFLPNYNGVLTATVFDKEIQRQTLANDGTVNGGVVTKMDFRTLGETIFRGQATVTNGNFDFNFVVPRDIGVPVGNGRVSFYSKQDNILDDKSGFNNEIQVGGINENAAEDNIGPVINLYMNDENFVSGGITNEQPTLLAKLQDDNGINTASGIGHDITAIIDGDEINPFILNDYYQANVDDYQNGKVSYPFRDLEPGLHTLTLKAWDVYNNAATAEIDFVVRDKDEELVIENVLNYPNPFIDYTEFWFNHNSSDVLDVSVQIFTVSGKIVRTLNGQTSGGSKVSSSLSKDIVWDGRDDFGDKIGKGVYIYKLKVRSNQLNKQVEKIEKLVIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFH2</accession>
    <name>A0A5C6ZFH2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Anti-sigma factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_11130</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018764">
        <property type="entry name" value="Anti-sigma_K_RskA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10099">
        <property type="entry name" value="RskA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="91"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="114"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="267" mass="29647" checksum="593595D54439C315" modified="2019-11-13" version="1">MDLKTYIESGILELYVAGQLSDQENREVYDQMRKHPEVLQEVLEIEAAVIKLTAAVSPKPSAYIFEHIKKHLGLNEEETKVVSITRPKHNWLTYASVAAAVLLGVGLFWSINQNNALEKQISDAEVENSYLEVQMEDTRKELAATENILKAIRGKDVIAIPLGGQGDFASTYAKVYWNKKENLIYLDAQGLPEAPEGKVYQVWSLTLNPLTPTSLGTIDDFNSDDTKIFNIKNTNESQAFGITLEPAGGSEIPTLEQLYTLGIVSTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFR9</accession>
    <name>A0A5C6ZFR9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Riboflavin synthase</fullName>
            <ecNumber evidence="4">2.5.1.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_13060</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.9" evidence="4"/>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004746">
        <property type="term" value="F:riboflavin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00402">
        <property type="entry name" value="Riboflavin_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023366">
        <property type="entry name" value="ATP_synth_asu-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001783">
        <property type="entry name" value="Lumazine-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026017">
        <property type="entry name" value="Lumazine-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21098">
        <property type="entry name" value="PTHR21098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00677">
        <property type="entry name" value="Lum_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000498">
        <property type="entry name" value="Riboflavin_syn_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00187">
        <property type="entry name" value="ribE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51177">
        <property type="entry name" value="LUMAZINE_BIND"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="Lumazine-binding" evidence="2">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="Lumazine-binding" evidence="3">
        <location>
            <begin position="1"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="Lumazine-binding" evidence="3">
        <location>
            <begin position="96"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="repeat" description="Lumazine-binding" evidence="2">
        <location>
            <begin position="96"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="196" mass="21760" checksum="6DC0E15882F5041D" modified="2019-11-13" version="1">MFTGIIEDLGTIRKLQQQQGNLQITLESKITSHLKIDQSVAHNGVCLTVVDISDDLYTVTAINETLKKTNLSNLEVGDKVNLERAMKLGDRLDGHIVQGHVDQIGLCEAVSEENGSWLYTFTYDASIGNVTIEKGSATVNGVSLTVVNSEKDRFSVAIIPYTYEHTNFKHLKKGSKINLEFDVLGKYIQRLYKAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFU4</accession>
    <name>A0A5C6ZFU4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Redoxin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10880</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="1"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="168" mass="19388" checksum="262E238EA6AE77CA" modified="2019-11-13" version="1">MKPREKTPDITIDLVNDTKWNLGEQDPKQFIMIVFYRGKHCPVCKSYLEELQEKLSKFTDRGVNVIAISANSEKLSKETYKEWNIPDIPVGFEFPIEDARTWGLFVSKGIKDEEPETFFEPALFLIKPNQELYCASIQTMPFARPSFDDIVKAIDFVVDKDYPARGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFU7</accession>
    <name>A0A5C6ZFU7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_12370</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="273" mass="31523" checksum="DFCC78B970102CE2" modified="2019-11-13" version="1">MRTKNISTQSSNILTYFNTLDQDCFIYAEAENALPASSNSALKELLSDMVKRGLLMRLKKGLYYIIPYEKDAESFMPDWHLIAGHLTKGENHYIGYYSALQIHNLITQPSLKEQIVVSKQMRPSIIKIKNVDFQFIYHNENHFFGAKKIWIDSFNKVLCSDLEKTFIDCLFKPDYAGGIVEIARAIYTSKDNIKFDTLFEYAERFKSQAVIKRLGFLLEILEIETAIIPKLNKLKTTSYVLLDTELPKSGKMISRWSIQQNLETETIKSAIYT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG03</accession>
    <name>A0A5C6ZG03_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sensor histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_14000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="127"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="347" mass="40194" checksum="5FEEC87ED5AB0013" modified="2019-11-13" version="1">MNKKLKKTYKFAYKTSLYLTLFMTLILGVFLYLLQAFDIIYMLVFAIATYFVSFLTIQHRVERFIYRRVQKIYDDLTLLESTSLRRQPITTDMATLTRQIDKYAKERKIEIETLKVREEYRKEFLGNVSHELKTPLFTVQGYISTLLDGAKDDKALLDKYLMRANKGVERLIYIVKDLDMITKLEVGDLSLNIKAFDIVDLVQSVIELLEMKAAKKKISLIFDRDYSEPIMVMADRERIQQVLTNLVTNSIKYGKEKGTTEISIENLIKNKVIVRVTDNGEGIANNNIPRLFERFYRVDKSGSRKEGGSGLGLSIVKHIIEAHDERIYLESELAVGSEFSFTLEKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG24</accession>
    <name>A0A5C6ZG24_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">trxA</name>
        <name evidence="6" type="ORF">ESY86_14105</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the thioredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005746">
        <property type="entry name" value="Thioredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000077">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01068">
        <property type="entry name" value="thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2 4" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="5">
        <location>
            <begin position="1"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="4">
        <location>
            <begin position="30"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000077-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD88227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="105" mass="11422" checksum="8FEAC7F2ED9DCD93" modified="2019-11-13" version="1">MALEITDATFEETVLKSDKPVVVDFWAAWCGPCRMVGPIIDEISTEYEGKAIVGKMDVDANQEFAAKYGVRNIPTVLVFQNGEVVGRQVGVAPKNAYTDAIDALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG83</accession>
    <name>A0A5C6ZG83_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">PAS domain S-box protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_09985</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016772">
        <property type="term" value="F:transferase activity, transferring phosphorus-containing groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="2">
        <location>
            <begin position="19"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="3">
        <location>
            <begin position="93"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="1">
        <location>
            <begin position="163"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="376" mass="42723" checksum="B2CF840C6C05D93F" modified="2019-11-13" version="1">MKIICYLNSTMPEEISHVKEKLFENIFNYAKGGIAIVSPKGKWLKVNASIVDLLGYSKNEIYSMTFQDITHRDDLESDMEYFNQILSGEIDSYQIQKRFFHKNGAIVWGHINVSVFKDEVGEPRYFISQITDITAQKEAALHHNLLMDIIQDKNKTLNDFAHIATHDIRTHVGNLDSITGFIEEDCKPIVAHESFLMWKESVKNLQETLSHLDDIRTVQSSQKKDLKALPLHDYINHAIYNVAGIARKQDVVISNNVDTSLKVRAIAAYLDSIILNFLSNAIKYKSQDRLPKIEISSRYEDSYAIIDIKDNGIGIDLDKHGHQLFTLNATFSDHEDSRGIGLFITKNHIESIGGKIEVESELGKGTCFSVYLKNAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGI8</accession>
    <name>A0A5C6ZGI8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Fasciclin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_11155</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02469">
        <property type="entry name" value="Fasciclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00554">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="SSF82153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50213">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023123423" evidence="2">
        <location>
            <begin position="22"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="3">
        <location>
            <begin position="55"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="191" mass="20299" checksum="BB8C77AFFB24B29E" modified="2019-11-13" version="1">MKTIKKFCFVLAFAALLSACKEEDKGTTTATPVAETENTSSERTGQAFIKDDVGKPTVLSIAMNSKDHTTLVAAVQAAQLENVLVNAGPLMVFAPTNAAFEALPDGTVENLLKPENKEALANILKYHVTPGNYSKEFLMKFKKLGQANNGYVKVEVVDGEPMVGGAKILASVPAGNGIVHVIDKVLLPPTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGK9</accession>
    <name>A0A5C6ZGK9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Potassium transporter TrkA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_11500</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013099">
        <property type="entry name" value="K_chnl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07885">
        <property type="entry name" value="Ion_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02080">
        <property type="entry name" value="TrkA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02254">
        <property type="entry name" value="TrkA_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51201">
        <property type="entry name" value="RCK_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="58"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="83"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="RCK N-terminal" evidence="4">
        <location>
            <begin position="132"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="5">
        <location>
            <begin position="262"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="RCK N-terminal" evidence="4">
        <location>
            <begin position="354"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD88852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="568" mass="62921" checksum="707120376ECB6ADB" modified="2019-11-13" version="1">MKFVGSQLAYYLKDTDFKRNYKVLLKYLALLAAVIIIYSILFHFIMGLEGQDHSWVTGFYWTLTVMSTLGFGDITFASDLGRLFSIIVLLSGIFMLMIVLPFAFIRHFYVPLLESKNKNKVPREVPAGTKNHILICSYDVIARDLTERLEQENTPYFIIEDDLEKALKNHDENIPVLIGALDNKDTFLLANIKDAKLILVNRDDFFNTKIILTIREIAPTTPIVAIATNIESVDVQQLSGADHVLPVKKWLGEQLASRVNTQHAESHAIGQYEDLLIAELPIHNTPLVSKRIRDTGLRQKFGVSIVGIWERGKLQPIKGDEILTHYSVLVIIGNKEQLNNIDEIFNDYDVNPNPVLLIGAGKVGLAAAESLHKNGVLVNVVDMDPEVCKNVSPFCNQVFSGDASDYKLLKKAGILEAPSVLLSTHDDTTNIYLASYCRQLNKDLRIVSRISEARNVEIMQKAGANFVLSYSTLGSEAVLSISKGQDLTVLGEGFTLFIIPIPKSLEGKSLAESGIGAKTGLSVIAIKENSEVVTVLAANTILPHGAEIVMLGNTEMKHEFNKIYVNGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGL5</accession>
    <name>A0A5C6ZGL5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SPFH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_12640</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="domain" description="PHB" evidence="2">
        <location>
            <begin position="19"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="308" mass="34572" checksum="9902BD82FA683FC9" modified="2019-11-13" version="1">MEKFILIPILFFGFIILISAFFIVNQQTAAIVERFGKFHSVRQSGLQLKIPLIDKIAGKLSLKIQQLDVIIETKTLDDVFVRLKVSVQYRVIKTKVYDAFYELDYPHEQITSYVFDVVRAEVPKMKLDDVFVKKDDVALAVKAELNEAMSTYGFDIIKTLVTDIDPDAQVKQAMNRINASEREKIAAQFEGDAQRILIVEKAKAEAESKRLQGQGIADQRREIARGLEESVEVLNRVGINSQEASALIVVTQHYDTLQSLGEETNSNLILLPNSPQAGSSMLNDMVASFTASNQIGEAMKNARKKEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGP0</accession>
    <name>A0A5C6ZGP0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase</fullName>
            <ecNumber evidence="6">2.3.1.191</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_10405</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.191" evidence="6"/>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016410">
        <property type="term" value="F:N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103118">
        <property type="term" value="F:UDP-3-O-(R-3-hydroxymyristoyl)-glucosamine N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03352">
        <property type="entry name" value="LbH_LpxD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007691">
        <property type="entry name" value="LpxD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020573">
        <property type="entry name" value="UDP_GlcNAc_AcTrfase_non-rep"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43378">
        <property type="entry name" value="PTHR43378"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04613">
        <property type="entry name" value="LpxD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="1" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="LpxD" evidence="5">
        <location>
            <begin position="26"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD88901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="311" mass="33789" checksum="7934DB8F1753E78A" modified="2019-11-13" version="1">MKFPKPHTLKEIAELIHSEYVGAEDFPVLGMNEIHVVEPGDIVFVDHPKYYDKALLSAATIVLINKQVDCPEGKALLISDDPFRDFNKLTQHFKPFQASKSAKAESAKIGKNTIVQPNCFIGNNVKIGNDCVIHSNVSIYDDTIIGNHVTIHAGSVLGANGFYYKKRPEGFDQLKSGGRVVIHDHVDIGALCTIDKGVTGDTTIGEGSKLDNQIQVGHDTIIGKKCLIAAQVGIAGCVVIEDEVTIWGQVGIASGLRLAKGSVILAQSGLGHDTQEGKSYFGSPAKLARDEYREMAYIKQIPELIKKLNQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGW3</accession>
    <name>A0A5C6ZGW3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fe-S cluster assembly protein SufD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">sufD</name>
        <name evidence="3" type="ORF">ESY86_08305</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0051 (ycf24) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000825">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037284">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011542">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045595">
        <property type="entry name" value="SufBD_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43575">
        <property type="entry name" value="PTHR43575"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01458">
        <property type="entry name" value="SUFBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19295">
        <property type="entry name" value="SufBD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101960">
        <property type="entry name" value="SSF101960"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01981">
        <property type="entry name" value="sufD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SufBD_N" evidence="2">
        <location>
            <begin position="18"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="437" mass="49606" checksum="7B7DF6A36254F13A" modified="2019-11-13" version="1">MELKDKLVSSFMAFENLVDVESPIHDVRSEAIKTFEDEGFPSKRNEDWKYTSLNSILKHDYSVFPKQENHTEYRDIKKYLINDIDSYKIIFIDGKYSSHLSQTTHEGIDVCLMSSALAKPKYRPIIENYFNKAATKDSISSLNTAFSQEGAYIHIPKNKLVEKPIQIVHFSTGNESALMLQPRNLIVVDENSHVQIIERHQSLTENPVLTNCVTEIFAGKRSIVDYYKIQNDKQSASLIDNTFIKQKDESHASVHTFSFGGNLTRNNLSFYQEGERIDSTLKGVTIIGDKQHVDHNTLVHHIEPNCESHQDYKGIFGDRSTGVFNGKVLVNKEAQKTNAFQSNNNILLTDKASINTKPQLEIFADDVKCSHGCTIGQLDEDAMFYMQSRGIPEKEARALLMFAFSNNVMNSVKIPEIKQRITKIIANKLGVNLGFDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGX8</accession>
    <name>A0A5C6ZGX8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">ATP-dependent 6-phosphofructokinase</fullName>
            <shortName evidence="15">ATP-PFK</shortName>
            <shortName evidence="15">Phosphofructokinase</shortName>
            <ecNumber evidence="15">2.7.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Phosphohexokinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15 17" type="primary">pfkA</name>
        <name evidence="17" type="ORF">ESY86_10505</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 15">Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6-bisphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16109"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 15">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="15">Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5 15">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 15">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.11" evidence="15"/>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00182"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003872">
        <property type="term" value="F:6-phosphofructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00339">
        <property type="entry name" value="Phosphofructokinase_I_B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022953">
        <property type="entry name" value="ATP_PFK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012003">
        <property type="entry name" value="ATP_PFK_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012828">
        <property type="entry name" value="PFKA_ATP_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015912">
        <property type="entry name" value="Phosphofructokinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000023">
        <property type="entry name" value="Phosphofructokinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035966">
        <property type="entry name" value="PKF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00365">
        <property type="entry name" value="PFK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000532">
        <property type="entry name" value="ATP_PFK_prok"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00476">
        <property type="entry name" value="PHFRCTKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53784">
        <property type="entry name" value="SSF53784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02482">
        <property type="entry name" value="PFKA_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00433">
        <property type="entry name" value="PHOSPHOFRUCTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 15" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="12 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 15" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="14 15" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="11 15 17" id="KW-0418">Kinase</keyword>
    <keyword evidence="13 15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 15 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PFK" evidence="16">
        <location>
            <begin position="7"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="ADP binding; allosteric activator; shared with dimeric partner" evidence="15">
        <location>
            <begin position="25"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="15">
        <location>
            <begin position="130"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="15">
        <location>
            <begin position="174"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="ADP binding; allosteric activator" evidence="15">
        <location>
            <begin position="190"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="ADP binding; allosteric activator" evidence="15">
        <location>
            <begin position="218"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="15">
        <location>
            <begin position="258"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="15">
        <location>
            <position position="132"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="76"/>
            <end position="77"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="106"/>
            <end position="109"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="159"/>
        </location>
        <ligand>
            <name>ADP</name>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <note>allosteric activator</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="TXD88918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="328" mass="35502" checksum="13FE97E728DA072B" modified="2019-11-13" version="1">MPKTIKKIGVMTSGGDSPGMNAAIRSVVRTCAYHKIECVGIYRGFEGMIEGDFKSMDARSVKDIINKGGTVLKSARSQEFRTVEGRKTAHDKLIEANVDALVIIGGDGSFTGALIFNNEFDFPVMGIPGTIDNDIFGTTHTLGYDTALNTVVEVIDKIRDTASSHNRLFFVEVMGRDAGHIALNVGVGAGAEEILIPEEDLGLDRLLESLRRSKQSGKSSSIVVVAEGDKIGKSVFELKDYVEANMTEYEVRVSVLGHMQRGGPPSCFDRVLASRMGVKAVESLLDGQTNYMVGLLNDVMALTPLDHAVKGKTKINLELLRVSEIMST</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH13</accession>
    <name>A0A5C6ZH13_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Patatin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_13780</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043864">
        <property type="entry name" value="Omp85-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19143">
        <property type="entry name" value="Omp85_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="1 2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022871895" evidence="3">
        <location>
            <begin position="19"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="domain" description="PNPLA" evidence="4">
        <location>
            <begin position="31"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXGXXG" evidence="2">
        <location>
            <begin position="35"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="2">
        <location>
            <begin position="62"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="2">
        <location>
            <begin position="208"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="64"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD88165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="744" mass="83438" checksum="F62500828D764979" modified="2019-11-13" version="1">MKRTLLILTLLFSAALSAQDLEQPNPKKIGLVLSGGGAKGFAHIGVLKVIDSLGIKVDYIAGTSMGAIVGSLYASGYSGKQLDSIFNSVNFDNVINDIIPRSSRTLYERDNTEKYAIVLPFDRFKLKLPSSLSRGQNVFNLLSKLTLHVSEIHDFDKLPIPFFCVATNVETGNAVILDSGNLALSVTASGAFPTLFQPVEIDGALLIDGGVINNYPIEELRAKGIDIIIGVDVQDGLATRKDMTSAPDVLLQINNFRTIKDMIPKREKTDIYINPDIKGFTVIDFSQGRKIIESGAKAALDKLDELETLTKYGSGVISEKMDLRSKDSIRINSINIKGNDRYTKAYIMGKLKLKGNETVDYDLFDRGVNNLIATNNFNSFIYAFKRSKGEEGYDLEANLKESKISTFIKFGLHYDDVYKSAALLNLTKKRLLFKNDFASLDIILGDNVRYNFEYLIDKGFYWSIGIRSRYNQFQKSINAELFLDDSQIAGTGINKIDVKLRDQTNQFYIQTLFRKDFAISLGAEHKRLNVKSETITIADQTGDFVFENTDYFSVFGSLKLDTYDNPYYPSSGLYFSGYFHTYLLASGFNTNFTEFSIAKAEAGYAFSVSNRLSFNFKTSGGFKVGEDNTQSLNFALGGYGNKFINNFIPFLGYDYISLIGDSYVKGYVGMDYKLFQKHHLTLEANIANVDNNIFETGEWFTLPDYRGYALGYGIESFLGPIQVKYSYAPELKESTWYFNLGFWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH83</accession>
    <name>A0A5C6ZH83_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carbonic anhydrase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the beta-class carbonic anhydrase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001765">
        <property type="entry name" value="Carbonic_anhydrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036874">
        <property type="entry name" value="Carbonic_anhydrase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11002">
        <property type="entry name" value="PTHR11002"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00484">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00947">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53056">
        <property type="entry name" value="SSF53056"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="254" mass="27462" checksum="ED80AB72979A5FE2" modified="2019-11-13" version="1">MTTTIRKISIAMLCLGLMSCENNKKETDTNMASEPQQVQQTPIRSIMTAEEQGSMSPDEIIGRLKKGNENFVSNNLTRRDHSAQRRMATIGQYPKAIVLSCVDSRVPVEDVFDLGIGDIFVARVAGNIENKDIVGSMEFATAVAGSKVVIVMGHTACGAVHHAIDNTDAASMGMNALADLLNEIKPSVEATEKNGDVSSKNLAFTNDVITNNAKRTVKDIRASSPRMAELESNGKLKIVAAVYDMETGKVKFLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHN0</accession>
    <name>A0A5C6ZHN0_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Cell division protein FtsZ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 9" type="primary">ftsZ</name>
        <name evidence="9" type="ORF">ESY86_09410</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="4">Assembles at midcell at the inner surface of the cytoplasmic membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the FtsZ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051258">
        <property type="term" value="P:protein polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02201">
        <property type="entry name" value="FtsZ_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00909">
        <property type="entry name" value="FtsZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000158">
        <property type="entry name" value="Cell_div_FtsZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020805">
        <property type="entry name" value="Cell_div_FtsZ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045061">
        <property type="entry name" value="FtsZ/CetZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024757">
        <property type="entry name" value="FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30314">
        <property type="entry name" value="PTHR30314"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12327">
        <property type="entry name" value="FtsZ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00423">
        <property type="entry name" value="CELLDVISFTSZ"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="SSF52490"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="SSF55307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00065">
        <property type="entry name" value="ftsZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01134">
        <property type="entry name" value="FTSZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01135">
        <property type="entry name" value="FTSZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4 5 9" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 4 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0717">Septation</keyword>
    <feature type="domain" description="Tubulin" evidence="7">
        <location>
            <begin position="21"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin_C" evidence="8">
        <location>
            <begin position="216"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="547"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="596"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="610"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="29"/>
            <end position="33"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="117"/>
            <end position="119"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD89251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="648" mass="70881" checksum="559FC81E205B1266" modified="2019-11-13" version="1">MSNNNDIGNIAFDLPKNQSNVIKVIGVGGGGSNAINHMFLQGIKGVDFVICNTDSQALHSSGVPNKIQLGVNLTEGLGAGANPEVGEQAAIESLEDLKRMMDTNTKMVFITAGMGGGTGTGAAPVIAKLAKELDILTVGIVTMPFQFEGKTRNEQAQKGIETLRSHVDSLVVINNNKLREVYGNLGFKAGFSKADEVLATASRGIAEVITHHYTQNIDLRDAKTVLSNSGTAIMGSATASGKTRAQEAIMKALDSPLLNDNKITGAKNVLLLIVSGAQEITIDEIGEINDHIQNQAGHGANIIMGVGEDESLQESISVTIIATGFDIDQQNEISNTEAVKVVHALEDEKEETPFLRQKRNINPANTVSEEAPKKPDVVVHKLIDDVVPDSPKSNRSADPQFVKTTDIIKNISVVHDEVLDHKFKEEDFVITPAKIEPTKIVDTKEEEQVTLMFDMPLPDKRNKVEEPKASETEKPKVYGLEDDVNDIKVNEHVEIIPVTEANETGEKRYALDDFTTYESSINASKNASKTKEKPEVEEDVVFEKKTIQPEALATEQTPEVDPMTSPISDLLKERADERRRNMKEFNYKFSNAKIDEIEREPAYKRKGVNIENSRPSSETSASRTSIGTDDNDDVQLRSNNSFLHDNVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHQ5</accession>
    <name>A0A5C6ZHQ5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_09620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002686">
        <property type="entry name" value="Transposase_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036515">
        <property type="entry name" value="Transposase_17_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01797">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01321">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143422">
        <property type="entry name" value="SSF143422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Y1_Tnp" evidence="1">
        <location>
            <begin position="9"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="185" mass="22128" checksum="3B405671A4B83186" modified="2019-11-13" version="1">MSRNYKFHNKSGLYFVSFATVNWIDVFTRHPYFDVLGESVKYCREKKGMELYCYCFMPSHVHFIFRSTNEQPSGLLRDFKRHTSKRVLEAIENNPQESRKEWLLWMFERAGKKNAATSKYQFWQHHNKPIELWSDKVIKQKIDYIHNNPVEAGFVTNPIDWKYSSARNYQEDHTILEIDSTGFLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHT4</accession>
    <name>A0A5C6ZHT4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_08930</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD89493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="233" mass="25571" checksum="89083F11F4ED47E2" modified="2019-11-13" version="1">MIQTIELTKKYGDFTALDKLNLSIKEGEIFGLLGANGAGKSTAINMLLGFLNPDSGKVQINDIDATKNAKDARKIIGYIPENVNLYPYLSGVENLDYFCRLAGLKYSKTELQDFLASCGLQSEANDQKVSAYSKGMRQKVGIAIAYAKKAKVYLLDEPASGLDPLASKELSILLKKLASEGATILMASHDIFRVREVCNRIGILKSGILVKELYAKDVSANELETLYLKFMQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI17</accession>
    <name>A0A5C6ZI17_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_06370</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007492">
        <property type="entry name" value="LytTR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04397">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00850">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50930">
        <property type="entry name" value="HTH_LYTTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="9"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="HTH LytTR-type" evidence="3">
        <location>
            <begin position="140"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="239" mass="27486" checksum="D9C8A1CF9B8A2764" modified="2019-11-13" version="1">MSTQTKPIACLIVDDEPAARDIIAMHLSQIENIRVIAQCESAVEAFQHIQRQNIDLIFLDINMPEVSGIAFAKSINSSIQVIFTTAYRDYAVEGFELKAVDYLLKPISFERLKKAVQRYFEIQEQASPKIQESENASEFMFVRADRKMLKIDFEAIFYIESIGDYLKIHLASKTIVTRETMTVVEAKLPNAHFMRIHRSFIINIPKLQSFTSEHITILNSALPISRSYKKSVLNYLEKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI42</accession>
    <name>A0A5C6ZI42_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="109" mass="11460" checksum="BEAFAD520E495F88" modified="2019-11-13" version="1">MKLKRIDPVKYATIAAILTALIMLIVFVPMALLFSLIGAGAASESFGAGAAIFGGGIFMVVLIPIIYAVVAFIVTLISTALLNFILRKTGGLDIDFEKSGLDITQIGQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI78</accession>
    <name>A0A5C6ZI78_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ATP-binding cassette domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_08945</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD89496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="210" mass="23496" checksum="EE0CF43119501E19" modified="2019-11-13" version="1">MVQTDNLIFHYKKKENHIFKFPDITLNEQENLLILGKSGIGKTTLLHLLAGLLNPVSGEVMIEGVAINTLSHWGLDKFRGQHIGLIFQKNYAVQSLNIVENLQARLFFSGKSVNNKTIDFFLEQLGLKDCKKSKANELSEGQLQRLGIAMAVIHGPKVILADEPTSSLDDENCEMVINLLIKQAKQTKANLIVITHDHRIKPLFSNSISL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI86</accession>
    <name>A0A5C6ZI86_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SulP family inorganic anion transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_06870</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015116">
        <property type="term" value="F:sulfate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011547">
        <property type="entry name" value="SLC26A/SulP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01740">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00916">
        <property type="entry name" value="Sulfate_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="231"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="273"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="306"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="331"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="360"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="STAS" evidence="2">
        <location>
            <begin position="408"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="509" mass="54737" checksum="C2FA67A1CC7F298E" modified="2019-11-13" version="1">MKKYLNLFDFKQKVNYKTEVLSGLTVALALIPEAVAFALIAGLSPLTGLYAAFVMGLITSIFGGRPGMISGATGAVAVVIVALAISHGPEYIFATVILAGIIQILAGVLRLGKLMRLVPHPVIFGFVNGLAIIIFMSQLDQFKDASGSWLTGQSLYILLGLVLLTMLIIWGLPKLTKAIPSSLVAILAIFAIVVGFGIDTKTVGDIASIQGGFPPFHIPNVPFNFETLALIFPYAAIMAGVGLIESLLTLNIIDEITETRGRGNKEAVAQGVANMLSGVFSGMGGCAMLGQSLINVSNGARARLSGIVASVALLLFVMFGAGLIEQLPMAALTGLMIMVAVGTFEWASLKTFNKMPKSDIFVMVVVTLVTVVLHNLALAVIVGVIIAALVFAWDNAKRIRARKSIDDQGIKHYEIYGPLFFGSVTLFNEKFDVLNDPEEIIIDFKESRVVDMSAIEALNKLTERYSKLNKKVHLRHLSSDCKNLLRNADKIIDVNVLEDPSYKVVVDKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIJ6</accession>
    <name>A0A5C6ZIJ6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07725</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022910195" evidence="1">
        <location>
            <begin position="22"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="168" mass="18722" checksum="00260AA4B45D9666" modified="2019-11-13" version="1">MKLEFSTVACFFMTIILISLSACTSAQKLQENAPTNFGKVYFQKWNSGVQGGGSGLHIYIPVEEASVTLDSVYFRGQVSALKQNPNNELLFIGSFKTAINAPKDLIMSDDPNKERENKLPSAAMNSRFKLDDDQCVVSYKKESKTVYYKISNLEEAQQINYPSTAPNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIK1</accession>
    <name>A0A5C6ZIK1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_07205</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="65" mass="7198" checksum="21B398F7E72CCF77" modified="2019-11-13" version="1">MSYKEGIIEIGEQITVAGIAQWKSLSEPIPEYPYAQIASLEASEGQKIIITDLPEALVEPKLRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIN2</accession>
    <name>A0A5C6ZIN2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Aminopeptidase P family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_08245</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070006">
        <property type="term" value="F:metalloaminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007865">
        <property type="entry name" value="Aminopep_P_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_NTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05195">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01011">
        <property type="entry name" value="AMP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="SSF53092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0464">Manganese</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP_N" evidence="3">
        <location>
            <begin position="6"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="430" mass="49439" checksum="FFA8CC7820EF9058" modified="2019-11-13" version="1">MKYHKINKDLFIKNRKNFMSKMKDSSLAVFNSNDIYPISADSTMPFQQSRDIFYLSGVDQEESVLVLFPDCPKEKHREILFLKETNDHIAVWEGEKLTKEAAFETSGIKTVYWLKDMDKVLFELMTQCDTVYVNTNEHYRANIETETREARFIKTLLEKYPAHSVAKSNPILQRLRSVKDPIELKLMQEACTITEKGFKRVLDFVKPGVWEYNIEAEFMHEFLNNRSRGFSYTPIVASGNNANVLHYVENNQECKAGDLILIDAGAEYANYSSDMTRTIPVSGKFTKRQKEVYNAVNRVKKEATKLLVPGAFWESYHVEVGKMMTSELLGLGLLDKADVQNEDKDWPAYKKYFMHGTSHHIGLDTHDYGILTEPMQANNVFTVEPGIYIPAEGFGIRLEDDLVIQEKGEPFNLMGDIPIEAEEIEELMNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIV9</accession>
    <name>A0A5C6ZIV9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">M56 family metallopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_08815</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008756">
        <property type="entry name" value="Peptidase_M56"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05569">
        <property type="entry name" value="Peptidase_M56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="90"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="179"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="265"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M56" evidence="3">
        <location>
            <begin position="162"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="374"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="374"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="646" mass="73152" checksum="7592A1DCA38EF415" modified="2019-11-13" version="1">MIMLIYLLKSSACLAVFMLFYKLFLEGSSIHHFKRFYLLATLLLAFVIPKITFVELVEPMVYNFEGLTTTTQASFTEALPQAQSSNLLPILLWTLYAAGLLVFLVKFCLNLFRIYARVRHNPTYKSKGFIQVLIENLIIPHTFFNYIFLNKSKFETDQIPKEVLLHEQTHAKQKHSIDVVLLELFQIVFWFNPLIYILKNDIKLNHEFLADAAVLKHGIKTSTYQSILLAFSSKASHQQLANAINYSSIKKRFTVMKTQSTPRSIWLRSLLILPLLAFLLFGFAQREQLVKKNADSTTNAMDTVYESVTTQNTQLQKGATKAQLAAYNKLAKHYNARANDNRVIKLKDMKRLYDIYALMDAQQKANAEPYPNFPPPPPPPAVGETSVIKKLPPPPPIPPNASAKQKSVYKKALKNYEQQVQAYTYAHKNKDGENITVTVIPDGDDLTPPPIPNQKGVIEVPMNAQAPPERVTNKRYKKPIEIVEMPTEDPFDVSTKFINIEGLLIYAVSIDGKTKYYNAQGFEVNDIGQKISKTQVNASDVIPGQYITSIYKNSKVMVVFNDNMPGQIETIYETPTPPIPPKPLSPLELVKSMAEKNAEFYYESKSVSSEKAIELLKKKEDLNIQVKSINSQTPLVYITKAPIGSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJA0</accession>
    <name>A0A5C6ZJA0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ESY86_03150</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="89"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="171"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="195"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="276"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="19"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="371"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="403"/>
            <end position="410"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD90378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="608" mass="67814" checksum="CB9D74C99989CBF8" modified="2019-11-13" version="1">MDYIKKLSRFIFPYRRYAILNIICNIFYALFSTLAMVSLMPMINVLFGESEKVYEKPVYGGIRNITNFVENYLNYVVTTTTTNEGPQQALLYMIILIISMFLLKNIFNYLGLFFITFLRNGVLRDIRDEMYLKVITLPISYYSEKKKGDIIARISGDVAEVKNSMLSVLELIVKEPLTIIFAIITMFAISTKLTIFVFLFIPVAGFIISLIGKSLKRKSGKVQREQGVFLSTLEETLAGLKVINGFNSQKRFYGKFQDSTNRYYEFSNTLMNRENLASPTSEFLGIATIAALLWYGGNMVMVEQTLSGGAFIGYMALSYQILTPAKAISKASYRVKSGNAAADRILEILETQNNLEDKATAIKKADFQSQIALKNVSFKYEDDLVLKNFSITVPKGKSVALVGQSGSGKSTIANLVTRFYDVSDGAIEIDGIDIRDLTKHSLRGLMGLVTQDSILFNDSVKNNILIGKEDATDLEIIEALKIANAWEFVKDLPKGIETNIGDAGGKLSGGQKQRLSIARAVLKNPPIMILDEATSALDTESERLVQVALENMMKNRTSIIIAHRLSTIQNADEIIVMQKGQIAEQGTHNQLLAKDGVYKKLVAMQSFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJF2</accession>
    <name>A0A5C6ZJF2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GIY-YIG nuclease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05290</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035901">
        <property type="entry name" value="GIY-YIG_endonuc_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01541">
        <property type="entry name" value="GIY-YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82771">
        <property type="entry name" value="SSF82771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GIY-YIG" evidence="1">
        <location>
            <begin position="2"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="84" mass="9851" checksum="4B27FA6E58F707CF" modified="2019-11-13" version="1">MLDFVTYILASEKTANLYKGHTSNLIGRFKSHNGLSKKGWTVRYRPWRVVYVRFFATKSEAMGHEHWLKSGAGREWIKDHLKVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJG1</accession>
    <name>A0A5C6ZJG1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sulfur reduction protein DsrE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_04870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027396">
        <property type="entry name" value="DsrEFH-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75169">
        <property type="entry name" value="SSF75169"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023122516" evidence="1">
        <location>
            <begin position="24"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="140" mass="15734" checksum="198B9F760AB1B5C1" modified="2019-11-13" version="1">MKTYIFSSIFLMLSLFSNTHLEAQQLNSSKNNYVLLTKKVAQLQPIILTAEALKAEDGESFGDFQVIICGREIGDITDSEKMDPFIEKAEKAGVQLIACGFSLNKFKIDKTKVPKKMKIVENGILHNFQLQKKGYKSISL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJJ0</accession>
    <name>A0A5C6ZJJ0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">PA0069 family radical SAM protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_07450</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040086">
        <property type="entry name" value="MJ0683-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43432">
        <property type="entry name" value="PTHR43432"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01084">
        <property type="entry name" value="Uncharacterised_Radical_SAM_Su"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Elp3" evidence="6">
        <location>
            <begin position="73"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD89729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="362" mass="41067" checksum="3B7798EBC6795BCD" modified="2019-11-13" version="1">MSRFNSESYSKIKGRGAQKNVHNRFFELSHEQRDDFLNYCAIEGEQPDQNKTEYLKVFPKTIVNKVKSPDVGMAYSMNMYQGCEHGCVYCYARNSHEFWGYGAGLDFERKILVKADAPKLLEAFIKRKSWQAHPIVMSGNTDCYQPAEKKLEITRACLEIFLKYKHPASIITKNALILRDLDLLKALAKDHLISVNMSITSLSEDTRRIMEPRTASIKKRFEAVNLLSEHGIPVNVMMAPIIPSINSHEILALAKLASEAGASKFSHSIVRLNGAIGQIFADWLHKSLPDRAEKVLHQIEDCHGGTLSDSRLGTRMRGEGQIAKQINDLGKLARLKYFKHKSMPCLNVDLHESYKDGQLRLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJW5</accession>
    <name>A0A5C6ZJW5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_05055</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="101" mass="11400" checksum="23CE59834F2DED9E" modified="2019-11-13" version="1">MKLVIVTAVEEFQKDVLKLFKKANIESFSSSDIDGHKNGSSILMASSWFSGEKAGNESRLFFSFTEDQYIDDLFQLIEVFNSNLETSNPIKAVVVPIEKFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK00</accession>
    <name>A0A5C6ZK00_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amidohydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_03980</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022993413" evidence="1">
        <location>
            <begin position="22"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="Amidohydro-rel" evidence="2">
        <location>
            <begin position="316"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="436" mass="47805" checksum="E10F338702ED00D8" modified="2019-11-13" version="1">MKTFYKLTLLALIFNFQLGSAQQTPAAKQSQPIAITGATAHIGDGTIIENSILVFKDGKLTTVADSAMTKIDLSGMEVIDASGKHVYPGFIAPNSTLGLVEIDAVRATDDDSELGSWNPHIRSLIAYNAESKIVESMRPNGVLIGQITPRGGRISGTSSVVQFDAWNWEDAAIKVDDGIHMSWPNSFSRGRWWLGEDPAMKVNEDYDKQVTEIQSYFNASKAYENGDTKTINLPYAAVAGLFDGSKTLYIEVNDEKGITDAIHFANSENVKAMVIVGGYEAYKVADLLAKNNIPVLLNRVHSRPNAADDDYDLPFKLAKLLTDKGVMVALQADGQMERMNTRNLPFYAGTTVAYGLTKAQALQLITLNPAKILGIDKDYGSLEVGKSATLFISEGDALDMRTNILSRAFIDGRDLSLETHQTELWKRYSKKYSAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK23</accession>
    <name>A0A5C6ZK23_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Bifunctional metallophosphatase/5'-nucleotidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_04875</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 5'-nucleotidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009166">
        <property type="term" value="P:nucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008334">
        <property type="entry name" value="5'-Nucleotdase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036907">
        <property type="entry name" value="5'-Nucleotdase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006179">
        <property type="entry name" value="5_nucleotidase/apyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575">
        <property type="entry name" value="PTHR11575"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02872">
        <property type="entry name" value="5_nucleotid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01607">
        <property type="entry name" value="APYRASEFAMLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55816">
        <property type="entry name" value="SSF55816"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="2">
        <location>
            <begin position="27"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="5_nucleotid_C" evidence="3">
        <location>
            <begin position="332"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU362119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD90306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="534" mass="59547" checksum="36BE1D3FA49001CB" modified="2019-11-13" version="1">MLSVSCKTETPKSTASATSTKDTLSITILQTADIHGQLDTHPELFWENEKVVFKNRGGLANIKTLFEQERKKNPNRTIIVDGGDLIQGSGYTALSEGKVLPEIIKNMGYDVIIPGNWEVVYGKEIMMDIMAGYETDVIVQNMYHDKTKAPLFPSYSIKEIEGVRIGFIGLNDPDVPVRQNPVFSEGIGFSGLDGELKKIVDDIKVNEKIDVLFLVTHIGIFKQIELANNPIAENADYILGNDTHERVRVPIQGTYAKVTEPGAFGSFVGKLTLHFVDGTLVDDAYELIDVDPEVFPADETIQALVDKAKAPYKAHLETVVGYTNTPIYRYLTVENPMDNMITDAARWKTGADISISNGFRFGNPIVPKNGKPEPITRANLWNLLPVNEPVKTGKATGKQIKDWLEKEMHNAFAQNPTERFGGWLVRFSGMKVNFNSQNDKGNRISAIEVNGEPMVDEQYYTVSACVRPGDPLDNLCRIPNVKDVEVMDYTIHEAVEAYLKKNSPISPSLEGRAYCDYLGRYSFSTVPNTDYKFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK34</accession>
    <name>A0A5C6ZK34_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">YqaE/Pmp3 family membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_06855</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0057 (PMP3) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000612">
        <property type="entry name" value="PMP3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21659">
        <property type="entry name" value="PTHR21659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01679">
        <property type="entry name" value="Pmp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01309">
        <property type="entry name" value="UPF0057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="26"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD89912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="50" mass="5406" checksum="F214ADE8827BBBC8" modified="2019-11-13" version="1">MSILTIILSILLPPLAVFMKKGLGGAFFLNILLTLIGWIPGVIHAFIVND</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK79</accession>
    <name>A0A5C6ZK79_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NUDIX domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_03245</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="3">
        <location>
            <begin position="29"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD90396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="183" mass="20706" checksum="9DF43EB6D8AEEC01" modified="2019-11-13" version="1">MDEHIDILSKNGKPTGASVPKSEIHAKGHYHNTAHVWFYTHDGHILLQQRSAKKSICPLLWDVSVAGHVDTGETIKQAIVRETREEIGLLISETDLKKIGVFEGFQSYPSGIIDNEFRHTFIAETSAKLEDLTIQKEEVEALKFISITEFESILKNIGKDQHFVPSNKTYYEFVLEAILEELG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK98</accession>
    <name>A0A5C6ZK98_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Molecular chaperone DjiA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_07300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3680.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007791">
        <property type="entry name" value="DjlA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029024">
        <property type="entry name" value="TerB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05099">
        <property type="entry name" value="TerB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158682">
        <property type="entry name" value="SSF158682"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="SSF46565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="198"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="55"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="261" mass="29294" checksum="F7FF6A0F945C05B6" modified="2019-11-13" version="1">MGVTKWIGGALGWAFGGPIGAIIGLALGSLVDGASKSDFPFLGQGDRKQDASRQSTRGTFRSAQQRPQTQPGDFEVSLLILASVVIKADGHQDQRELDFVRQQFVSMYGKDRANQAFSLFKNINKQQIPTRQVCLQIKQMMDHASRLQLLHFLFGIARADGMVTDTEVSQIYMIAGYLGISSRDYDSIKAMFYNSSDNAYKILEITKAATNDEVKAAYRKMAKKYHPDKVMHLGKEHQEGAEEKFRQVQLAYEQLQKERGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKA9</accession>
    <name>A0A5C6ZKA9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Ferritin-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_02015</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="250" mass="26826" checksum="EE0A3EB778632EA8" modified="2019-11-13" version="1">MKNASKNESTTEGKTFKNRRQFLKLSGMAVLGSGLLIACSDDDDIINTPDPIFDLGAGNLGILNYAYALEQLEAAFYTKVLDGGYWAGAATNEKIIMEDLYNHEIIHREFFRTAITSVAPDQIVPDLEFDFSSVNFDSRESVLNISQILEDTGVKAYNGAGQLIDVSDDAGQAYLLLAGKIVSVEARHASAIRDLIDPGSMDFAGDDILINLGGTGLAYDKAATPTEVLTEVGATGFVVTPFTANNLPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKE8</accession>
    <name>A0A5C6ZKE8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 12">Fructose-bisphosphate aldolase</fullName>
            <shortName evidence="12">FBP aldolase</shortName>
            <ecNumber evidence="5 12">4.1.2.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="primary">fbaA</name>
        <name evidence="13" type="ORF">ESY86_09995</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 12">Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>beta-D-fructose 1,6-bisphosphate = D-glyceraldehyde 3-phosphate + dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:14729"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.1.2.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11 12">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11 12">Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 12">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 12">Belongs to the class II fructose-bisphosphate aldolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.13" evidence="5 12"/>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00183"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004332">
        <property type="term" value="F:fructose-bisphosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00946">
        <property type="entry name" value="FBP_aldolase_IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000771">
        <property type="entry name" value="FBA_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006411">
        <property type="entry name" value="Fruct_bisP_bact"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30559">
        <property type="entry name" value="PTHR30559"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01116">
        <property type="entry name" value="F_bP_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001359">
        <property type="entry name" value="F_bP_aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00167">
        <property type="entry name" value="cbbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01520">
        <property type="entry name" value="FruBisAldo_II_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00602">
        <property type="entry name" value="ALDOLASE_CLASS_II_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00806">
        <property type="entry name" value="ALDOLASE_CLASS_II_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="8 12 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 11 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11 12" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Dihydroxyacetone phosphate binding" evidence="10">
        <location>
            <begin position="262"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Dihydroxyacetone phosphate binding" evidence="10">
        <location>
            <begin position="283"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="9">
        <location>
            <position position="106"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="223"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>dihydroxyacetone phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU366023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TXD89094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="355" mass="39086" checksum="D3E173BF3E9DF648" modified="2019-11-13" version="1">MSHSIKAGVATGKEVQAIFEHAKKNNYALPAVNVIGSNTINAVLETAKSLNAPVIIQFSNGGAQFNAGKSLSNDQQKSAIAGAIAGAKHVHLMADAYGVPVILHTDHCAKKLLPWIDGLLDASEQHFKETGKPLYSSHMLDLSEEPIEENIAICKEYLSRMSKMGMTLEIELGITGGEEDGVDNTDVDDSKLYTQPEEVAYAYEELSKISDQFTIAAAFGNVHGVYKPGNVKLTPKILKNSQEFLSKKHNLPHNHIDFVFHGGSGSTVEEIKEAIGYGVIKMNIDTDMQYAFLSGVRDYIQDKKDFLQTQIGNPDGDDVPNKKYYDPRVWLRKGEDAFVERLKKAFEDLNNVNTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKM5</accession>
    <name>A0A5C6ZKM5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_08005</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="562" mass="63733" checksum="509C535788AA9C66" modified="2019-11-13" version="1">MNKKKYHERTRAQESSNAIERMYITMRHLFNRGFYKPMGISGETLRESLLILRPEIYGSIADEKAELEGLLYVIDRLPQGIEECTFINLTSDEGYGNSHFKTIIPPKRRRNCYRIDDEQMNIEVTRGRSEIYDILTHLTFMFVESHKISKKVLIDENGATTRDWVKLENAVLSTKKLTQKEREIALTHTANILGRTFDELTNAHHQFTTNTKPERLLHVVYWLGKLAIEEVINNNKRTVTFSPVLRERLGHHIHGEIWADHIKETLHKNKLINRPIHIISANMHSVMNSIFAPNALKGMANKKDIFSVYEALSKSDSETIRNKVTKEALQNGMIYIKDTSGTNIDVQIFDTEKIDFSKSDFKVGKSFEDGEKPVIIVMDYAFGEQAYETMDELLKPFKVDKEKVFLNVESVSLMGKAGILEGGKGDIMIPSAHIFEGTADNYPFHNELSKSHLDNQGVAICEGTMITVLGTSLQNKEILKFFFNSTWNVIGLEMEGAHYQKAIQAAAKVRGSIRPDVKVRYAYYASDNPLETGGTLASGGLGTSGVKPTYLITRTILGQIFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKP0</accession>
    <name>A0A5C6ZKP0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Metal ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_07310</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ABC-3 integral membrane protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001626">
        <property type="entry name" value="ABC_TroCD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30477">
        <property type="entry name" value="PTHR30477"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00950">
        <property type="entry name" value="ABC-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="72"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="101"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="147"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="190"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="258"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD89587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="375" mass="41008" checksum="55EC26107CBA15B3" modified="2019-11-13" version="1">MNLQEYFSLVFSDYTLRTITLGTAILGAVTGMLGSFAVLRKQSLLGDAISHAALPGIAIAFLITGAKDSNTLLLGALVSGLIGTFWIRGIVSKTHLKSDTALGLILSVFFGFGMLLLTYIQKQPNANQAGLDKYLFGQAATLVESDVWLMAIVTGVSLCVMLLFWKEFKILLFDKDYAETLGFNTKTIDVLITVFIVLAIVLGLQTVGVVLMSAMLLAPAAAARQWTNSLSTMVVLASVFGAFSGVFGTAISASQNNLSTGPVIVIVAAVFVLISFIFSPSRGLLFRQIRFVKNRRDLELQKTLSFMFHIAETHDDISHPHEIRILNNFQGFTKGSLKTLEEKNYIRLEGSTWSLTDQGFETASNLYNQQHQNNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKS2</accession>
    <name>A0A5C6ZKS2_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Abasic site processing protein</fullName>
            <ecNumber evidence="7">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_02440</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the SOS response-associated peptidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="7"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:cellular response to DNA damage stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018142">
        <property type="term" value="P:protein-DNA covalent cross-linking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1680.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003738">
        <property type="entry name" value="SRAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036590">
        <property type="entry name" value="SRAP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13604">
        <property type="entry name" value="PTHR13604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02586">
        <property type="entry name" value="SRAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143081">
        <property type="entry name" value="SSF143081"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0190">Covalent protein-DNA linkage</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD90837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="245" mass="28215" checksum="EDAE1499F8E4FE58" modified="2019-11-13" version="1">MCFHTSIALPLKKTERRFKVKLHDEQLRAQFSKAQYHLNGFAHPNVLLIPQEKSNVLAPGIWGIVPQDKLANEIKAYQKEAVKFGGGLNARSEKLFEHFVYRESAMTRRCIIPVSGFFEPHTHKRKKYPFYIHQKNKEPMALAGIYTVIENYVTFAILTKSASPLFEKIHNLKKRQPLILDEVQTHNWLSSDLTETDVKTIVGFNFPESQLEAYSVSKTLFSPKTDSNIESITDKVVYDELLSFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL64</accession>
    <name>A0A5C6ZL64_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4293 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_04230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025635">
        <property type="entry name" value="DUF4293"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14126">
        <property type="entry name" value="DUF4293"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="136" mass="15285" checksum="FEFA865CAA2B190B" modified="2019-11-13" version="1">MIQRIQTIYLLLAAIASGGLIFVFHLWTNSEDVAVYAKDNYLYLGLFLGSALLSLISIFSYKTRKFQFVLGRLNIILNFLLLGLLIYQLLMPPGESHISEKGVGIFIPIISTVLLVLANKAIKKDEDLVKSVDRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL68</accession>
    <name>A0A5C6ZL68_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">DUF421 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_06940</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UPF0702 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.240.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007353">
        <property type="entry name" value="DUF421"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023090">
        <property type="entry name" value="UPF0702_alpha/beta_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04239">
        <property type="entry name" value="DUF421"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="38"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD89928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="167" mass="18572" checksum="86531EB801DFCD52" modified="2019-11-13" version="1">MTFLDALYLILSVIGIFTIIIVITRVFGLRTFAKMSSFDFASTIAIGSILASIILNKDYSLFKGTLALATIIAFQTLFSFLVRKVPSFKKLFTNKPQIIMWQGKILHDKLKACNVGEDDLIAKLREANVHDFKDVKAVIFESTGDVSVIHNAENRSISPDLLKDVAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL78</accession>
    <name>A0A5C6ZL78_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_06995</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="172" mass="18311" checksum="F7CA8886D7F724C6" modified="2019-11-13" version="1">MKYLIIAIILILSINVSGQNEVVDANIFIRIYNLQGKKIEKGKIKSISNTSIELYSKGKTIEVPLSKIGIIKTKRSAGNNVAKGALIGGVSLAVLGYSDGDDNSGLALFSATDKAAFGLVGGGILGAAIGGVTSIFKKSKLYIIDGNEMKLKDFKEAMLLERMTKAKKNTEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLB4</accession>
    <name>A0A5C6ZLB4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Threonylcarbamoyl-AMP synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_04495</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006070">
        <property type="entry name" value="YrdC-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01300">
        <property type="entry name" value="Sua5_yciO_yrdC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="SSF55821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00057">
        <property type="entry name" value="TIGR00057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51163">
        <property type="entry name" value="YRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YrdC-like" evidence="1">
        <location>
            <begin position="7"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="191" mass="21050" checksum="FD0657F14A05D55C" modified="2019-11-13" version="1">MTTEQQKIEVQKALQALKKGGLILYPTDTVWGIGCDATNAEAVQKIYKLKQRDDSQALICMVNNYGMLEKHVDNVPKMAYTILDVAIKPTTIIYDHPAGVAENLIAADNTLAIRVVKHKFCEQLIKYLGKPLVSTSANISSQPTPKSYKEISEHILKGVDYVVNLQNEKSASQPSAIIKLGNDGKVVVVRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLE0</accession>
    <name>A0A5C6ZLE0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05610</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="121" mass="13175" checksum="086CFC62A76FE0B6" modified="2019-11-13" version="1">MMVLNEGGPAMYIILLLLLLSLFFIVKAFLSKTKDEAHSKKMIGLAIDSSLLSLVIGCLGSLLGIIDLFDMAQALGETRPDLFSVGLKVSLLTIAFGLLSFVIGRLGILIYKWSLKSELEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLK3</accession>
    <name>A0A5C6ZLK3_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Tyrosine recombinase XerC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">xerC</name>
        <name evidence="13" type="ORF">ESY86_00765</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the 'phage' integrase family. XerC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009037">
        <property type="term" value="F:tyrosine-based site-specific recombinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01808">
        <property type="entry name" value="Recomb_XerC_XerD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004107">
        <property type="entry name" value="Integrase_SAM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023009">
        <property type="entry name" value="Tyrosine_recombinase_XerC/XerD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02899">
        <property type="entry name" value="Phage_int_SAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3 9" id="KW-0132">Cell division</keyword>
    <keyword evidence="4 9" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="2 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0229">DNA integration</keyword>
    <keyword evidence="7 9" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6 9 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="12">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="11">
        <location>
            <begin position="108"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="153"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="248"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="251"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="274"/>
        </location>
    </feature>
    <feature type="active site" description="O-(3'-phospho-DNA)-tyrosine intermediate" evidence="9">
        <location>
            <position position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TXD91154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="302" mass="35109" checksum="502C0BFF4CE81426" modified="2019-11-13" version="1">MLWSQALNDYKYYLKIERGLSSNSIKNYEYDVLKLIKFLDENQISISPTEIDYQKIQQFIYEASKKLNARSQARLISGLRSFFSYLVFEDYRDTNPLDHIESPEIGRKLPDTLSIGDIDRLIAAIDLAKTYNNVAIGERNRTILETLYSCGLRVSELIALKISDLFFDEGFIKVTGKGDKERFVPINPNTQKYIAIWTQLRRHMNVDPRFNDTLFLNNRGKQLTRAMIFTIIKDLAKAINLNKTISPHTFRHSFATHLLENGADLRAIQMMLGHESITTTEIYVHVDRSHLKKTLMQFHPRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-02-10" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLS9</accession>
    <name>A0A5C6ZLS9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">YqgE/AlgH family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06720</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0301 (AlgH) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003774">
        <property type="entry name" value="UPF0301"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30327">
        <property type="entry name" value="PTHR30327"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02622">
        <property type="entry name" value="DUF179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="186" mass="20921" checksum="22210F4FF7AB60AA" modified="2019-11-13" version="1">MIITQPKKGTLLIAEPSITGDISFNRSVILLADYNKEGSVGFILNKPLSFELRDLIPQTNSDFKVHNGGPVEQDNLYFIHQVPHLIPESVEISNGVFWGGNFESVLELLAAGSLESSDIRFFLGYSGWGSDQLENELQSRAWIVLENIYKSDLIEKCQETFWKEKMIELGGDYSLWSNSPADPSYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLX6</accession>
    <name>A0A5C6ZLX6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RagB/SusD family nutrient uptake outer membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_01720</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SusD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033985">
        <property type="entry name" value="SusD-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012944">
        <property type="entry name" value="SusD_RagB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14322">
        <property type="entry name" value="SusD-like_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07980">
        <property type="entry name" value="SusD_RagB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="SusD-like_3" evidence="6">
        <location>
            <begin position="86"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="SusD_RagB" evidence="5">
        <location>
            <begin position="352"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD90708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="498" mass="55019" checksum="60D2711AC16B9710" modified="2019-11-13" version="1">MKKHVIYVLIFTAAIFSCSEDFLDPVRNTNVLTNDDIAGAVDNNPALVEGSLDGIANFMVEPRGTLGVGANRHYDIGQKGVDILSDIVTGDCALASSSFGWYNGTANLLATTDFTRQENQLLWDYYYRIIKSANTVILSSGGNDAVPENENTRRIIGQAKAYRAYAYFNLAQFFQPSYDPMQPILPFYDGDVSEFGKVEASRIYELIVSDLTQSITFLDGYVRTQKSQINKTVAQGLLAYTYAAMGNYIDAKIQSDAVINSGVPLLTRGQLAFPGTGSGFNDINTPSWIWGFDLTTDLGHQLIDWWGQMDYFTYSYAWAGDAKSIDNDLFADIPANDIRKTQFGQGFAALQPINKFFDPGRTPGGQFVISTDLLFMRVEEFYLLSAEAAARIGDESTALGRLTDLLEIRLGGSAEAATYLSGLSGQALLDEIYLQTKIELWGEGKSYFAMKRNQATVQRGTNHVFRAGESYAYDSDEASFQIPQIEINNNPSINDQNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLZ8</accession>
    <name>A0A5C6ZLZ8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF4136 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_01835</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025411">
        <property type="entry name" value="DUF4136"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13590">
        <property type="entry name" value="DUF4136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022745309" evidence="1">
        <location>
            <begin position="27"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4136" evidence="2">
        <location>
            <begin position="25"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="193" mass="21718" checksum="EE41B2FAF38D83EC" modified="2019-11-13" version="1">MKKLIKFLPVVMIAAVLTSCNSVKVAADYDKQVDFNTYKTFAFFKTGIDKAEISDLDKRRILRAIEAELFAKGLIKSENPDMLVSIFTKSQQRVDIYNNNWGWGGWGWGGFGWGGFGPGWGGFGPGFGWNNQPLVSTTNEGTLFIDFIDANKKELVWQGSGTGYLPSKMEKKDERIKEFVSKMMEKYPPGMNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM06</accession>
    <name>A0A5C6ZM06_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4255 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00540</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025351">
        <property type="entry name" value="Pvc16_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14065">
        <property type="entry name" value="Pvc16_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pvc16_N" evidence="1">
        <location>
            <begin position="13"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="206" mass="23359" checksum="9F31EC8A808BAC2A" modified="2019-11-13" version="1">MNTIVPVLEFIKDRIESFSGTSNSVSVGNVGLLSDDEFKSVNFSKIFITVLKIDEERLANNKNVYFIKDGNDDYSKRSNPQKSFSLNLLFAACSSNARYTDSLQRLEKVLECFQEQHIYEIPLPGRPENLQIVLEIQNMDLNQQNQLWSIIGGKYLPSVIYKVKLIPIQGIAEDGYGIIERVRIDLLDKSTADGFVIETTNDLTKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM13</accession>
    <name>A0A5C6ZM13_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_08000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="28"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="55"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="319"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="211"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="351" mass="39986" checksum="B6BDDA32531DD72F" modified="2019-11-13" version="1">MNENTPEQKSEEVDISQIFNLIGKAFKALFDFIVSIFEFILKTILLLALFIRNNIVKLGLAIVVGFVIGFISDRFEKDYYTSTMIVEPNFQANSQLITTIELYGQLVESNDSINLAKMLKISETDAAKISSISIEAKTNENTKIKGYNQFVKQTDTLVLKDVSFEAYKESLEEPDFDQYAITVNSTAYDIYGKIKDNIINIPTTAYVEALKKAEIENLDQMEREINQSLSDIDSLRAAYKTAMLNNSKNNNESGSSNNFYLGPDGQRKNTELELFEIETKYQYRLRDVFESKAQMESTINVVSGFTNIGIKAKNKNLKWYILISLGVMVLFIILANFNRYLSDFERKNKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM81</accession>
    <name>A0A5C6ZM81_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_02800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023017888" evidence="1">
        <location>
            <begin position="24"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="139" mass="15907" checksum="E12AE82E1A1FCA2B" modified="2019-11-13" version="1">MKQFFHKSLAVFMASVVFMTTMSFTMDMHYCGDTLVDFSFTQQVETCGMENTQNTSNCENPTLSEKSCCTDTQVIKKGQDDLKVSFDKLSLEQQIFVASFTYSYISLFEGTASEEIPFFDYAPPFVERDVQVLHQTFLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMK3</accession>
    <name>A0A5C6ZMK3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Kdo domain containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_04520</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="254" mass="30669" checksum="6A1C2FFA8337EE8A" modified="2019-11-13" version="1">MNFRVHNEYKTHTAALTNFILNFDTKGEDFGNQDRNSLKLFKIEAKTLNAKSFRIPNIINQVAYRFLRKSKAQRSFEYANRLQSLGIGTPQPVAYYEFKTWLLFKKSFYISEQLDCDLTYRELTTDSNYPNHEAILRAFTRFTYDLHEKQVKFLDHSPGNTLIEKVGEDYAFYLVDLNRMEFKSMDLEERIKNFAKLTTHKSMIEVMSDEYAKCSNLSYEEVFNLMWHNTQDFQRRYWRRRRIKNKLLFWRARK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZML3</accession>
    <name>A0A5C6ZML3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031165">
        <property type="entry name" value="GNAT_YJDJ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14542">
        <property type="entry name" value="Acetyltransf_CG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51729">
        <property type="entry name" value="GNAT_YJDJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="7"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="97" mass="11358" checksum="821C238F75745A00" modified="2019-11-13" version="1">MDAAELTDNDFLRQFEYKVDGAIAKIEYSLQDRKIFLTKLVVPDEIQNEDFAEEFLTLVFENISERNIGVVPTSPEIAKFIRRHRKYKKLLPVGIRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMY4</accession>
    <name>A0A5C6ZMY4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-succinylornithine carbamoyltransferase</fullName>
            <ecNumber evidence="2">2.1.3.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">N-succinyl-L-ornithine transcarbamylase</fullName>
            <shortName evidence="2">SOTCase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">argF'</name>
        <name evidence="6" type="ORF">ESY86_02235</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the transfer of the carbamoyl group from carbamoyl phosphate to the delta-amino group of N(2)-succinyl-L-ornithine to produce N(2)-succinyl-L-citrulline. Is essential for arginine biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>carbamoyl phosphate + N(2)-succinyl-L-ornithine = H(+) + N(2)-succinyl-L-citrulline + phosphate</text>
            <dbReference type="Rhea" id="RHEA:25884"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="ChEBI" id="CHEBI:58514"/>
            <dbReference type="ChEBI" id="CHEBI:58862"/>
            <dbReference type="EC" id="2.1.3.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-arginine biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the aspartate/ornithine carbamoyltransferase superfamily. SOTCase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.11" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00068"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016597">
        <property type="term" value="F:amino acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004585">
        <property type="term" value="F:ornithine carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1370">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02235">
        <property type="entry name" value="SOTCase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043696">
        <property type="entry name" value="ArgF'-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006132">
        <property type="entry name" value="Asp/Orn_carbamoyltranf_P-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006130">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036901">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006131">
        <property type="entry name" value="Asp_carbamoyltransf_Asp/Orn-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00185">
        <property type="entry name" value="OTCace"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02729">
        <property type="entry name" value="OTCace_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00100">
        <property type="entry name" value="AOTCASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53671">
        <property type="entry name" value="SSF53671"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="OTCace_N" evidence="5">
        <location>
            <begin position="7"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="OTCace" evidence="4">
        <location>
            <begin position="181"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Carbamoyl phosphate binding" evidence="2">
        <location>
            <begin position="47"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Carbamoyl phosphate binding" evidence="2">
        <location>
            <begin position="146"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Carbamoyl phosphate binding" evidence="2">
        <location>
            <begin position="268"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>carbamoyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <note>ligand shared between two neighboring subunits</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>carbamoyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>N(2)-succinyl-L-ornithine</name>
            <dbReference type="ChEBI" id="CHEBI:58514"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="175"/>
        </location>
        <ligand>
            <name>N(2)-succinyl-L-ornithine</name>
            <dbReference type="ChEBI" id="CHEBI:58514"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>N(2)-succinyl-L-ornithine</name>
            <dbReference type="ChEBI" id="CHEBI:58514"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="272"/>
        </location>
        <ligand>
            <name>N(2)-succinyl-L-ornithine</name>
            <dbReference type="ChEBI" id="CHEBI:58514"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="296"/>
        </location>
        <ligand>
            <name>carbamoyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD90800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="311" mass="35178" checksum="CD5731DEEE1FF7C0" modified="2019-11-13" version="1">MKKYTQINDIKNLQELIKEAILLKMNPYEYAHLGKHKTLVMLFFNASLRTRLSTEKAARNLGMNVSILNVNDAWNIEFEDGGIMNTNSTEHIKEAAKVISQYADVIAVRAFPSLTDKAKDQSEYVLRSFEKYATVPIINMESATAHPLQALTDAITISELADKPRPKVVLSWAPHPKALPQAVANSFVEMMQMMEVDFSITHPEGYELDEAITKNTPINHKQTEALKDADFVYVKNWSNFKDYGKILNQDPNWMMTEAKLGKAKFMHCLPVRRNVVVEDAVLDGDNSLVIKQANNRTFAAQVVLKHILEGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMZ5</accession>
    <name>A0A5C6ZMZ5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Asparagine synthase B</fullName>
            <ecNumber evidence="9">6.3.5.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_04655</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the asparagine synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.4" evidence="9"/>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004066">
        <property type="term" value="F:asparagine synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006529">
        <property type="term" value="P:asparagine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01991">
        <property type="entry name" value="Asn_Synthase_B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00712">
        <property type="entry name" value="AsnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006426">
        <property type="entry name" value="Asn_synth_AEB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001962">
        <property type="entry name" value="Asn_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033738">
        <property type="entry name" value="AsnB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00733">
        <property type="entry name" value="Asn_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13537">
        <property type="entry name" value="GATase_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001589">
        <property type="entry name" value="Asn_synthetase_glu-h"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01536">
        <property type="entry name" value="asn_synth_AEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0061">Asparagine biosynthesis</keyword>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="9" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="8">
        <location>
            <begin position="2"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="active site" description="For GATase activity" evidence="5">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="272"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="346"/>
            <end position="347"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for beta-aspartyl-AMP intermediate formation" evidence="7">
        <location>
            <position position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD90050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="553" mass="62783" checksum="3B0C402B23783238" modified="2019-11-13" version="1">MCGIVCAFDLKQKSEELRPQLLEMSKTLRHRGPDWSGIYSNDKAIMAHERLAIVDPASGKQPLVSADNKLVLAANGEIYNHRELRKQFPDYKFQTQSDCEVILALYEKKGADFIDEMNGIFGFAIYDAEKDEYFVARDHMGIIPLYIGWDQNGTFYVASELKALEGTCSKIELFPPGHYLSSKDGKFVQWYKRDWTEYDAVKDNETSIAKIKEALEAAVHRQLMSDVPYGVLLSGGLDSSVTSAIAKKYASKRIESDDTSEAWWPQLHSFSVGLEGSPDLAAARKVADHIGTVHHEIKFTIQEGLDAIRDVIYNLETYDITTIRASTPMYLMARVIKSMGIKMVLSGEGADELFGGYLYFHKAPNAKEFHEETVRKLSKLHQYDCLRANKSLAAWGIEGRVPFLDKEFMDVAMRINPQDKMINGERMEKWVVRKAFEDMLPASVAWRQKEQFSDGVGYSWIDTLKEMVNEAVSDEQIKNAHFRFPLQTPQNKEEFYYRSIFEEHFPSDAAALCVPQEPSVACSTKIALEWDEAFKNMNDPSGRAVSKVHADAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN03</accession>
    <name>A0A5C6ZN03_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MaoC family dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_01540</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd03450">
        <property type="entry name" value="NodN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002539">
        <property type="entry name" value="MaoC-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039375">
        <property type="entry name" value="NodN-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01575">
        <property type="entry name" value="MaoC_dehydratas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MaoC-like" evidence="1">
        <location>
            <begin position="21"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="154" mass="17284" checksum="D77B7AD44A03D194" modified="2019-11-13" version="1">MTKMVFDDLKAFRTFEGKTLPPGEWITVTQEMINDFAKATLDFQWIHVDVEKATQQSPYKKPVAHGFMSVSLLSKMLGDLLQIKSVKMGVNYGLNKVRFPNAVLVDSKLRLNGKITAIEPYNENGVKVTCDCTVEIEGAEKPACVAEFMSIMFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN13</accession>
    <name>A0A5C6ZN13_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Crp/Fnr family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_01590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="1">
        <location>
            <begin position="19"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="170" mass="20180" checksum="E598724F62CA2DF9" modified="2019-11-13" version="1">MKTIVQATDLENLKQKILSYTQVDDEVVREQMQYYQRMDLKKGDTLVTPGQLVHHFYYVATGCIYYYKLEEGEQKVLEFYTDDLFFTDLPAYVKGTPSNYYLKASEATVVYAIKKSDAEKSFEGSHQLERFGRLSMQEAFMKIFTRVERLNNRTNDERYLRLLEKRPDLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN21</accession>
    <name>A0A5C6ZN21_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4252 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025348">
        <property type="entry name" value="DUF4252"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14060">
        <property type="entry name" value="DUF4252"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023121522" evidence="1">
        <location>
            <begin position="23"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="193" mass="21464" checksum="99FE85A1CDA8CBA5" modified="2019-11-13" version="1">MKNLKKLSLMLVFALIGTSVFAQSIFDKFEDKDGVMSVVVNQKMFKMLATMGLDVDDPEAQGYIEMAKKITGLKVFTTGDEKISADMSATVNSYLKSSKLEELMRIKDGDQTVNFYVKEGKDENHVMELLMFVNGLKGLTNGNDISINGEKREFESVLLSLTGDIDLREISKLTSQMNMPGGEQLKKAGKNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN72</accession>
    <name>A0A5C6ZN72_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 11">Phosphate acetyltransferase</fullName>
            <ecNumber evidence="5 11">2.3.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">Phosphotransacetylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">ESY86_05120</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Involved in acetate metabolism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>acetyl-CoA + phosphate = acetyl phosphate + CoA</text>
            <dbReference type="Rhea" id="RHEA:19521"/>
            <dbReference type="ChEBI" id="CHEBI:22191"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.1.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="11">The N-terminal region seems to be important for proper quaternary structure. The C-terminal region contains the substrate-binding site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">In the C-terminal section; belongs to the phosphate acetyltransferase and butyryltransferase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">In the N-terminal section; belongs to the CobB/CobQ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.8" evidence="5 11"/>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00340">
        <property type="reaction ID" value="UER00459"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008959">
        <property type="term" value="F:phosphate acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006085">
        <property type="term" value="P:acetyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1390.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010766">
        <property type="entry name" value="DRTGG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016475">
        <property type="entry name" value="P-Actrans_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004614">
        <property type="entry name" value="P_AcTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042113">
        <property type="entry name" value="P_AcTrfase_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042112">
        <property type="entry name" value="P_AcTrfase_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002505">
        <property type="entry name" value="PTA_PTB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028979">
        <property type="entry name" value="Ser_kin/Pase_Hpr-like_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07085">
        <property type="entry name" value="DRTGG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01515">
        <property type="entry name" value="PTA_PTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006107">
        <property type="entry name" value="PhpActrans_proteobac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75138">
        <property type="entry name" value="SSF75138"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00651">
        <property type="entry name" value="pta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11 14" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DRTGG" evidence="13">
        <location>
            <begin position="215"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="PTA_PTB" evidence="12">
        <location>
            <begin position="372"/>
            <end position="691"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00021528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR006107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF07085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TXD90130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="697" mass="76070" checksum="6167C571E32B8B4F" modified="2019-11-13" version="1">MNKAIYIATTEPNSGKSIVSLGMMQSLLGKAAKVGYYRPIIDDFKPGKIDNHINTVSTYFNLDIKFEDAYAFTRSQVIKMKNEDKDDEIISKIIEKYKAIEDRFDFVLVEGTSFTGEGSIIEFDINVLIAKNLGVPAIILASGVGKTLEELVGNLQMAFDSFEEKGVEVLSVIANKVEDKNQALVVSELEKYLPSQVIVGAIPTNPILANPSIKEIVEVLQAKVLFGADYINNQAGNFSVGAMQLRNYLTHLKENGLVITPGDRADIILGALQANISENYPSISGIVLTGGLIPEESIIKLIEGLSDIVPIISTNEGTFAVANSIGTIKSRIYAENTQKIITSIQDFEKYVKVDALVNRLITFKTSGITSRMFQYNLLKKAKSNKKHIVLPEGLDERILTATKQLIDLDAVKITLLGDRKQIEEKIATLGIALDLNNINIINPIASVHFEAYAQTLYELRKHKNVNLAMAKDLMEDVSYFGSMMVYKGDADGMVSGAIHTTQHTILPALQFIKTKPEASIVSSVFFMCLEDRVSVYGDCAINPNPTSEELAEIAISSAATSLAFGIEPKIAMLSYSSGTSGVGEDVERVRKATEIVKSKRPDLKVEGPIQYDAAVDIKVGKIKLPDSEVAGQANVFIFPDLNTGNNTYKAVQRETKALAIGPVIQGLNKPVNDLSRGCTVDDIFNTVIVTAIQAQDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNW5</accession>
    <name>A0A5C6ZNW5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Diacylglycerol kinase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">ESY86_00730</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial diacylglycerol kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14265">
        <property type="entry name" value="UDPK_IM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.3610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000829">
        <property type="entry name" value="DAGK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036945">
        <property type="entry name" value="DAGK_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033717">
        <property type="entry name" value="UDPK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34299">
        <property type="entry name" value="PTHR34299"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01219">
        <property type="entry name" value="DAGK_prokar"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TXD91147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="125" mass="13835" checksum="1E92D34119B1FD5B" modified="2019-11-13" version="1">MAKKESLLINRLKSVRYAYNGALFLFKTEASIKVQVAFAILVTVAGFYFKISNTEWILQVICIGLVLSLEGINTAVEYMADFIHPDHHTSIGRIKDIAAGAVFMAATSAFIVALIIYLPRLIDLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPC6</accession>
    <name>A0A5C6ZPC6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF1573 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011467">
        <property type="entry name" value="DUF1573"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07610">
        <property type="entry name" value="DUF1573"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022737707" evidence="1">
        <location>
            <begin position="24"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="165" mass="17376" checksum="D6ACC153AE897D7A" modified="2019-11-13" version="1">MKKAILGLSALCLVAFTSCKEDATQKINSENVAAAAERDATAGDFPTINFDETEHDFGTIANGTPVQTVFKYTNSGNAPLVVSNIKSTCGCTVPSDWSRDPLAPGESAEFTVKFDGKGTNQVSKTITLTTNTEKGAETVKIKAFVEKDPNAPVSKAGSAAIKQVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPF5</accession>
    <name>A0A5C6ZPF5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_02765</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="182" mass="21454" checksum="3BA6BE235D26E710" modified="2019-11-13" version="1">MKNARTTTVKILMAIGLVGTMISCKSTFNANETLQVDENRNAIYQEIISNPVQLTNFISEAQKSEAAKKLMMQAHMAQMESGNMKMMMEKNPEMKEKMQSHMQMMMEENPEMMQKMYSKMLNKMMENEKDRKMLMDEIHSNKMMKKDMKAMMMQLMNENPEMKEEMKEKNPEMMKKMKNEGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPI7</accession>
    <name>A0A5C6ZPI7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Low molecular weight phosphotyrosine protein phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_01130</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the low molecular weight phosphotyrosine protein phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006470">
        <property type="term" value="P:protein dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023485">
        <property type="entry name" value="Ptyr_pPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036196">
        <property type="entry name" value="Ptyr_pPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017867">
        <property type="entry name" value="Tyr_phospatase_low_mol_wt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01451">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00719">
        <property type="entry name" value="LMWPTPASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00226">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52788">
        <property type="entry name" value="SSF52788"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LMWPc" evidence="3">
        <location>
            <begin position="2"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD91337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="147" mass="16536" checksum="75A9D359BA878CB9" modified="2019-11-13" version="1">MVCLGNICRSPLAHGLLESKLSQEDFYVDSAGTANYHVGDAPDARSIKVAKQHGIDISQQLGRQFQVSDFDSFDHIFVMDDSNYENLIKLARNEEDRVKVKSILSIDHSITANAVPDPYYGDFSDFEHAYDLLNKVTDILAEQLQKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPP9</accession>
    <name>A0A5C6ZPP9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">HD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_04485</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05398">
        <property type="entry name" value="NT_ClassII-CCAase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006675">
        <property type="entry name" value="HDIG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002646">
        <property type="entry name" value="PolA_pol_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032828">
        <property type="entry name" value="PolyA_RNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01743">
        <property type="entry name" value="PolyA_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12627">
        <property type="entry name" value="PolyA_pol_RNAbd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00277">
        <property type="entry name" value="HDIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PolyA_pol" evidence="4">
        <location>
            <begin position="27"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="PolyA_pol_RNAbd" evidence="6">
        <location>
            <begin position="182"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="HD" evidence="5">
        <location>
            <begin position="259"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD90630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="472" mass="53834" checksum="C2E3334DD9F9B622" modified="2019-11-13" version="1">MNYKEALKNPIFKIISQAAKDIGVDSYVIGGFVRDHILERGEHKDIDIVAIGSGIKLAKQVAKNLPNSPKVQVFKTYGTAMLVYEDMDIEFVGARKESYTQDSRNPIVENGSLQDDQNRRDFTINAMALSLSADSFGNLLDPFNGVEDLEHKIIRTPLDPDITYSDDPLRMMRAIRFATQLNFTIEAASLESIFRNKERIKIITKERIVVELNKILLSETPSVGFLLLEKTGLLEFILPELTALKGIDEVEGQTHKDNFYHTLEVVDNIAKNTEDVWLRWAALLHDIGKAPTKKFSKKVGWTFHAHEFVGSKMVYKLFKRLKMPLNEKMKFVQKMVFMSSRPIVLAQDMVTDSAVRRLIFDAGEYVEDLMILCEADITTKNPKRFKKYHKNFQVVRQKIDEVEARDHVRNFQPPVSGEEIMEAFDLKPSREIGQIKEAIKEAILEGDIPNEHEAAHQLMLKLGEKLGLKATL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZQD6</accession>
    <name>A0A5C6ZQD6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00645</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046125">
        <property type="entry name" value="DUF6122"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19617">
        <property type="entry name" value="DUF6122"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="104" mass="11746" checksum="73AB87157A5670F8" modified="2019-11-13" version="1">MIQSLIHYGIHFVAPMLVALLFYKPKWIRAYLIMCCGILIDLDHLLATPMFDPNRCSIGFHPLHSYYAIGFYLLLLLPKKTRLVGLGLVIHIMADLADCALMGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZQK2</accession>
    <name>A0A5C6ZQK2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cupin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_02805</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="114" mass="12695" checksum="26D1B426FEF922E2" modified="2019-11-13" version="1">MKTASLTNDIVYHKKRPTIQVLFETETGKEIRIAFKKDQVMKEHKTPFPIVVEIFEGSIDFGVNGKLHSLHKGDLVALEGGVPHDLTAIKDSIVRLSLNKADTAKRVEDVAKNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZQL8</accession>
    <name>A0A5C6ZQL8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphoesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_02915</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022742823" evidence="1">
        <location>
            <begin position="23"/>
            <end position="1236"/>
        </location>
    </feature>
    <feature type="domain" description="Metallophos" evidence="2">
        <location>
            <begin position="46"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1236" mass="140978" checksum="7BCD9D9D49525D61" modified="2019-11-13" version="1">MKIRTYRSPVILSLFLIFNACATYKAQYKDEADRTNQLPNKEVDKTFYLIGDAGKSPQGGMSQALTLFNKYTADKDTKDDYTIFLGDNIYPEGMPAEGEKGRAAAENGLDGQFMSLSNFKGKVIFIPGNHDWYSNGPKGLKAEENYVEAALGKGTYQPENGCPLEAFDIGDNIKLIVIDTQWYMEDWNKHPTINDECEIKTRERFFDELDGEFKKAQNRSVIVAMHHPMLTNGVHGGQFAISKHIFPTQKNIPAPILASLITQVRTQGGVSIQDRYNESYNKLMKRIETIAYDLKNVVFVSGHEHTLQYNEKENIKQIVSGSGAKESYAALSNTGLFVYGEQGFAELTVFKDGSSWVTFYGEENGAPKKLYVKEVLAPEDDFDSSTLPDSFPQEVETSVYTKEQTEKSDFFETVWGGHYRDVYSQKVKVKVATLDTLYGGLEIMRAGGGHQTRSLRLRTKDGRELNMRALKKSATQYLQAVLFKDTYIADEFEKTQVEGLILDFYTAAHPYAFAVIPDLSVAADIYHTNPKLYFIPKHKYLGNYNTNYGGELYMIEERPEENYTNERNFGYADDIESTHDILEKLRKDEKYKIDENTFIRARLFDMLIGDWDRHQDQWRWAQFDQENGDKVYKAIPRDRDQVFSNFDGSLLEVMRVIVGPSKQLQVYDEDLQNIKWMNAAGIKLDRVLIQNATREQWIKHAVFLQEHITDAVIDTAFTKVPKEVQDETLQEIKEKLKGRKSNLVDIANRYYDYLNELAILTGTDKDDYIEVTRIGDKQTHVKISRIKAGEKADVIVDRTFDAELTKEIWIYGLDDTDVFEVNGNGKNPIFIRLIGGQQNDTYKIKNGKHVKIYDHESKENTVVENKGATTRFTDIYKLNLFDYSKNIYKTNITTPSVAYNPDDGLALGVSFTTTKYGFQRNPFSQQHRFKGGYFFATDGISLDYEGEFANIKDDWNLQVGGTFTSENFTNNFFGYGNETVNAEDELDRDYNRVKTSIYKASAGIFKKGNFGSDYGFRAVFEGIQIGKTDGRFISDLVPETNEEFYERRWFGGLEAEYFYESYDNKLNPTRGMTFLLNLGGKADFDASERTFGYINSNLGFYNSISKNRKLVLKTDVRSQFRIGNDIIFYQAANLGGDNGLRGYRDERFTGNNSFVGTADLRYAFNSFKTNVLPLQIGVFGGFDVGRVWLKGDFSDKWHNDYGGGLWITAAESLSGTFNLFNGAEGLRFSFTFGLNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZRS8</accession>
    <name>A0A5C6ZRS8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transglutaminase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_01530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002931">
        <property type="entry name" value="Transglutaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01841">
        <property type="entry name" value="Transglut_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TGc" evidence="1">
        <location>
            <begin position="29"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="210" mass="24643" checksum="17C0E2AD5A999076" modified="2019-11-13" version="1">MDYLSSTYYFDFETEEIQQLVSEFKSDLISDKEKTKLLYLKVRDSWRYDPYHLSFSKENYKASTIAGKPKGHCVEKSIILIACLRALGIPARLHLGKVKNHIGVERLTEKFGTNELTPHGMVNVYLNHKWLKLSPAFNKTMCEIYNVSPSEFDGENNSYLQEFNNDGKIFMEYLEDYGHFEDVPLEFMITNVKEHYPHIFNKDNKSEFKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAI6</accession>
    <name>A0A5C6ZAI6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">YjgP/YjgQ family permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_18705</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000033">
        <property type="protein sequence ID" value="TXD86959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005495">
        <property type="entry name" value="LptG/LptF_permease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33529">
        <property type="entry name" value="PTHR33529"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03739">
        <property type="entry name" value="LptF_LptG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="277"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="301"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="331"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD86959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="358" mass="41404" checksum="2869638129045A3A" modified="2019-11-13" version="1">MKILDWYILKRYLFTFLMMLLLFIPIGITVNLAEKIGKILEREVPFAAVAQYYLDFTIYFANLLFPIFLFLSVIWFTSKLANNTEIVAFLSSGVSFWRFLRPYMIGATIVAAFALLLGLYLAPKASKGFNQFKYEYLKNNANVVQTSNIFRQVNDTDYIYVSNFNPATKVGSNFSLEHVVGNELKYKITANNIRYVEEDSVYRLSTYTKRKFQDNREVLETTRRKDTVFPFDVKDLTPEEYIAETLQYDELIDFIEKEKQRGSSNIGRYEVVKYKKWSLPVSVFILTIIAVAVSSKKRRGGMGVNLAFGISIAMIYVFFDKIFGVMAEQSSFNPIVAVWFPNIVFGILAIYLLYNAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAT4</accession>
    <name>A0A5C6ZAT4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NmrA family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000060">
        <property type="protein sequence ID" value="TXD86443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008030">
        <property type="entry name" value="NmrA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05368">
        <property type="entry name" value="NmrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NmrA" evidence="1">
        <location>
            <begin position="4"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="288" mass="33075" checksum="42DC563283C0BB29" modified="2019-11-13" version="1">MLKVLVTGATGNVGIEVLSSLKKLDHKLEIHAGVRDTEFGNEKLSNFNIKTIKFDFTNIETFLSALKDIDVLFLLRPPQISDVKKYFKPLIETAKESSIKHIVFLSVQSVENSKIIPHHKIEKLIVDSKIPYTFLRPAYFMQNFTSTLRNDLVNNHRIYLPSGQAKFTVIDVEDIGSVTAKVLIEPKNHINKSYELTNNETLTFAEMAEKISKGIGKTIKFISPNLLQFFLTKRKENMPTMLILVMIMLHYFPRFQKTPKTTDWVKIITGQEPKSFDDFVLTNLKQLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBJ3</accession>
    <name>A0A5C6ZBJ3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_17035</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000025">
        <property type="protein sequence ID" value="TXD87376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046230">
        <property type="entry name" value="DUF6263"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19777">
        <property type="entry name" value="DUF6263"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="298" mass="33170" checksum="73BCCD507B1A9292" modified="2019-11-13" version="1">MKSLAVKYLVVFIFGMLSGHAQMNLAYNLKQGDRFKIFQKADQNIVQDMEDTTHIVKNSIEGDFSFYVISVNDSVINVNFKFDRFKMNSTSNLAGNIMSVNTADLSNDEMQDKLFSGLTKTTLKMVLFSNGKIKSISGTEKLISRMVDAAGDMDEFTKELMKEAMKTEFGNESLSQSFEQLTYIYPTNSVKVGDSWQNAYTGDLSSENTWTLKGLTNGVYKISGKSKVHLITDDESVSMDLEGTMTSAVETYKSNGFIKSMETSSSASGLSTMKSMQGMKLPTTVNTKTTYKTETYVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBL6</accession>
    <name>A0A5C6ZBL6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Endonuclease V</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_20490</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000080">
        <property type="protein sequence ID" value="TXD86223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007581">
        <property type="entry name" value="Endonuclease-V"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04493">
        <property type="entry name" value="Endonuclease_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="167" mass="19418" checksum="26417CB24DD4D350" modified="2019-11-13" version="1">MILAFDTYYFNDKAKTVCLSFKDWFNEKPFEIYSETIPCIEEYVSGEFYRRELPNIISLMSKIDKAVIELIIVDGFVYLNDENKFGLGAYLHEKLNKQIPIIGVAKRTFATIEKNKVDVYRGKSKNPLFVTSIGIELKLAAKKIKEMEGEYRIPTLLKELDKLTREI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC48</accession>
    <name>A0A5C6ZC48_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">EamA family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_18710</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000033">
        <property type="protein sequence ID" value="TXD86960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="211"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="239"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="270"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="13"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="146"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="304" mass="34056" checksum="0D2833D3BA7D91E6" modified="2019-11-13" version="1">MPNAKTKNYLHLHLLVFIAGFTAILGELISIGSTALVWYRMCIAGVLMFLYIKMIRLKIKVSTKTKFKFFGAGIIIALHWITFFEAINQSNVSIALAMFSTGAFFASFIEPLFYRRRVIWYEIVFGLVVITGVFLITQSEIAYINGIVLGIVSALLSTLFSVINGRLIEQHSATVISFYEFISGLVFLSVFILVFQGGFSAQFFTLSAADAWYLFILASVCTAYAFIGAVDVMRYVSPYTVILTYNLEPVYGIVLAIFIFPETEIMSSQFYYGAFLVLSMVIADGILKNYKSHKKRIALASKPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC59</accession>
    <name>A0A5C6ZC59_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Chromate efflux transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">chrA</name>
        <name evidence="8" type="ORF">ESY86_19645</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000044">
        <property type="protein sequence ID" value="TXD86657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015109">
        <property type="term" value="F:chromate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014047">
        <property type="entry name" value="Chr_Tranpt_l_chain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003370">
        <property type="entry name" value="Chromate_transpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02417">
        <property type="entry name" value="Chromate_transp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004810">
        <property type="entry name" value="ChrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00937">
        <property type="entry name" value="2A51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="80"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="114"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="143"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="206"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="271"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="304"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="335"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="356"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD86657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="373" mass="40467" checksum="C3F78DFD12490887" modified="2019-11-13" version="1">MPNNKELIEIAKLFFKLGSIAFGGPAAHIAMMEDEVVKKRKWMTQEHFLDLVGATNLIPGPNSTEMTMHCGHERAGWKGLFVAGFCFIFPAVVITSVFAWLYQQYGQLPKVEPFIYGIKPAVIAIIIMAAFRLGKKAVKNMELAILGIITLVACLFGLNEIIALFGCGLLGLGIYFFKKNTGNLTSFFPLLLFQLVDPSKIGVLKIFLTFLKVGAILYGSGYVLFAFLDTELVANGWLTRQALIDAVAIGQITPGPVLSTATFIGWQMNGITGALAATIGIFLPSFLFVLILNPLIPKMRQSEILGAILDAVNVAAIALIIAVSVEMAKDTLTDWRTILIAVASLIVVFVFKKMNSAFIVLGGAVIGYLLTLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCI6</accession>
    <name>A0A5C6ZCI6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000041">
        <property type="protein sequence ID" value="TXD86732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="151" mass="16780" checksum="BBD203423A4748BC" modified="2019-11-13" version="1">MTQTGENTIGCLVNGEPFTDSGLMNNFYQFVNGDSVLAINWEQEKNGINRNGRIALRNIEVIPNQDYILNKNTLIDGAVEGGFGTYTFSIDNVQGGNEFRTNNNFSGVINFLKLDTENQIMSGTFEFEAEEINTGEIITVSDGRFDLTFVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCK2</accession>
    <name>A0A5C6ZCK2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">T9SS type A sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19510</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000041">
        <property type="protein sequence ID" value="TXD86728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Por_Secre_tail" evidence="1">
        <location>
            <begin position="374"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="453" mass="48842" checksum="D61A9788E98B20AC" modified="2019-11-13" version="1">MSYTKKLLWVVNITVNLTNRSYDNPVNLSYDKYAGGRYELFRGIDPIDYFDDDNVLIGDDPITQFQADLLNALVGSANINFNVEPTFGFIPTPSALDVGNGNTDLDDDDYFRVYNAANPPSGDLDIPFDNFITAYFDNNSLNEQHISFNFRNGTWLATELDAAVGNEDVFDCSFVCGGEGTISGRGIICLSSNFSIGNATTTTTWSIVPANAGNITINSNTQITVNRAFGYNGSATLIANISSPDCGATSITKAVFFGAPTGSASISGDDELNPGPADSAFFNVNTNNVNSGAGVSWLVYSGTDQNAPLYFSLTPSGSGNSVVVTANEDTPEGDYYMQARISNSCGYLPANKMFHVNEGGVPQYFPRTANSYSVYPNPSNTIVNVDLITAEVESTKSDTVISGELFDMLGKPKLKIELQNNTAVFSVAPLNPGVYVLQIYLVNHMETHQILVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCY1</accession>
    <name>A0A5C6ZCY1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000026">
        <property type="protein sequence ID" value="TXD87346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022972343" evidence="1">
        <location>
            <begin position="23"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="215" mass="25022" checksum="A767A10DFD2CF372" modified="2019-11-13" version="1">MKKSIYLLLALFISITMTNCSTEDENKIDDSASNIEKFDNNLTNFVNKAAKYSDLSQRLNYSDRNRNINEIILENKSIKDKNDLSDAKELNHNPNEFDKHFIQNILSSLTEDDILSFFNRMEFYEDFVNNNINDFQHKEYLINNIDGFKWVKYSLYELKESDVSKNNFDACFDGCMEDEINGQLGGGNPVKWAQFLLTAAETVAYWVGSCTWDCW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD32</accession>
    <name>A0A5C6ZD32_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000046">
        <property type="protein sequence ID" value="TXD86621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="73" mass="8645" checksum="872B7C82C198A024" modified="2019-11-13" version="1">MNIQAEKIHLAKLLLETENPKILESIKKIFKKDKTADFWDDLNLEQKEEIDNALLEIKNGQVTDYDSFMQNHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD43</accession>
    <name>A0A5C6ZD43_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-acetylmuramoyl-L-alanine amidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15815</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008745">
        <property type="term" value="F:N-acetylmuramoyl-L-alanine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02696">
        <property type="entry name" value="MurNAc-LAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002508">
        <property type="entry name" value="MurNAc-LAA_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01520">
        <property type="entry name" value="Amidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00646">
        <property type="entry name" value="Ami_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MurNAc-LAA" evidence="1">
        <location>
            <begin position="70"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="207" mass="24037" checksum="5C1DED370E86E2B6" modified="2019-11-13" version="1">MIVLLDNGHGALINGKYQTDGKRKDWGEKGIIYEGEFNRAIVNGIIEQLTYYQIPYVNIAPEYWDVRLETRVKRANKYTLKNSFYLSVHSNAGGGNGSEIFTSPGDTKSDKIATIFGGEFLREFPTRRLRTDYSDGDLDKESRFYVLTKTNMPAILTENFFMDNLEEFQEVLMSREGRQKIIDYHVRAILRTKVEIFRESTFTNFRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDB0</accession>
    <name>A0A5C6ZDB0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Alpha/beta hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_17805</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000028">
        <property type="protein sequence ID" value="TXD87169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022935040" evidence="1">
        <location>
            <begin position="20"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="Hydrolase_4" evidence="3">
        <location>
            <begin position="46"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="DLH" evidence="2">
        <location>
            <begin position="261"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD87169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="345" mass="39272" checksum="A76492AE09563792" modified="2019-11-13" version="1">MRKIGVLLILFSLTWNSQAQIQKILFDFEFEGAFLNGVLNMPDTIPKGVALIVHGSGKTNAVEQEWYYDVREQFVKSGYAVYMWDKMGCGASGGAFEYNQSVQNSALEVIAAIGALKKANISGSDKIGLWGISRAGWINPLVIDQYKDIQFWLSVSGVDAKENFKYLLKESLRINGYPKDAVTLLVDEWQKGVRITHSGGSFETYLEATPNLRDNEFLLRFTNGGITEEGYYTYQEGFMKEKLDEESGLQVYIKDFDNILSNTNCPVLALFGEKDMNVDWNKTKALYESTHRITSDLTIKSFPDCYHNMYKCKTGGFFEFQDNNLPRDRCEDFLKTMSDWLAKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDF3</accession>
    <name>A0A5C6ZDF3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Amino acid dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_15660</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Glu/Leu/Phe/Val dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006096">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006097">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00208">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02812">
        <property type="entry name" value="ELFV_dehydrog_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00839">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ELFV_dehydrog" evidence="2">
        <location>
            <begin position="181"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="408" mass="44848" checksum="90E4C56A20938051" modified="2019-11-13" version="1">MKELLQIYEDKEPEIIFNWKDPETEAEGWTVINSLRGGAAGGGTRMRKGLDMNEVLSLAKTMEVKFTVSGPAIGGAKSGINFDPNDPRKRGVLERWYKAVSPLLKSYYGTGGDLNVDETHEVIPITEASGVWHPQEGVFEGHFKPSIADKINRIGQLRHGVIKVIDDPKYSPNISKKYKIADMITGFGVAEAAKHFYDIKGESIVGKRAIVQGFGNVGAAAAFYLAQMGAKVVGIIDISGGVIKKEGFSFNEITDLYLNKKGNTLISKDLISFSEINEQIWALETEIFAPCAASRLITQSQIDQMIATGLEVVTCGANVPFADKEIFFGSIMEHTDQKVSLIPDFISNCGMARVFAYFMERKVLMTDEAIFSDTSETIREALQRVHDKNKTKTGISATAFEIALSQLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDM9</accession>
    <name>A0A5C6ZDM9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="12 13 14">UvrABC system protein B</fullName>
            <shortName evidence="13">Protein UvrB</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Excinuclease ABC subunit B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13 19" type="primary">uvrB</name>
        <name evidence="19" type="ORF">ESY86_17720</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 13">The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11 13 14">Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13 14">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="13">The beta-hairpin motif is involved in DNA binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13 14">Belongs to the UvrB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000027">
        <property type="protein sequence ID" value="TXD87273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009380">
        <property type="term" value="C:excinuclease repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009381">
        <property type="term" value="F:excinuclease ABC activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00204">
        <property type="entry name" value="UvrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001943">
        <property type="entry name" value="UVR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036876">
        <property type="entry name" value="UVR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004807">
        <property type="entry name" value="UvrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041471">
        <property type="entry name" value="UvrB_inter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024759">
        <property type="entry name" value="UvrB_YAD/RRR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24029">
        <property type="entry name" value="PTHR24029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12344">
        <property type="entry name" value="UvrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17757">
        <property type="entry name" value="UvrB_inter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46600">
        <property type="entry name" value="SSF46600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00631">
        <property type="entry name" value="uvrb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 13 14" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 13 14" id="KW-0228">DNA excision</keyword>
    <keyword evidence="9 13 14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8 13 14" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="4 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13 14" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="17">
        <location>
            <begin position="24"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="18">
        <location>
            <begin position="429"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="domain" description="UVR" evidence="16">
        <location>
            <begin position="626"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="622"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Beta-hairpin" evidence="13">
        <location>
            <begin position="90"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00026033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="TXD87273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="667" mass="76628" checksum="6DD2B37F4AB19085" modified="2019-11-13" version="1">MRFKVKSDFQPTGDQPQAIKKLTAGIEANEKYQTLLGVTGSGKTFTVANVIEEVQRPTLVLAHNKTLAAQLYSEFKQFFPENAVEYFVSYYDYYQPEAYIPVSGVYIEKDLSINEEIEKMRLSTTSSLLSGRRDVIVVASVSCLYGIGNPVEFQKNVISLEINQQISRTDLLHRLVQSLYSRTEAEFNHGNFRIKGDTVDVFPSYADDAFRIHFFGDEIEDIEQFNIQTNEVIEHYERLNIYPANMFVTSPDVLQGAIKEIQDDLVKQYDYFKDIGKHLEAKRLKERTEFDLEMIRELGYCSGIENYSRYLDGRLPGTRPFCLLDYFPEDFLMVVDESHVTISQVHAMYGGDRSRKVNLVDYGFRLPAAMDNRPLKFEEFEALQNQVIYVSATPADYELQKTGGVFVEQLIRPTGLLDPVIEVRPSLNQIDDLIEEMQQRIEKDERTLITTLTKRMAEELTKYLDRIQIRCRYIHSDVDTLERVEIMQDLRKGVFDVLVGVNLLREGLDLPEVSLVAILDADKEGFLRSNRSLTQTVGRAARHLNGKAIMYADKITNSMQKTIDDTEYRREKQIAYNTKHNITPTALKKSLDSALSRNSVSTYSYALEAAKAAEPESKYLTKEQLEKKIKEKRKLMEQAAKALDFIIAAQLRDELKGYQEKLQAVKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDN4</accession>
    <name>A0A5C6ZDN4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Potassium channel protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_16205</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013099">
        <property type="entry name" value="K_chnl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07885">
        <property type="entry name" value="Ion_trans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02080">
        <property type="entry name" value="TrkA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02254">
        <property type="entry name" value="TrkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51201">
        <property type="entry name" value="RCK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0407">Ion channel</keyword>
    <keyword evidence="6" id="KW-0406">Ion transport</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="66"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="RCK N-terminal" evidence="4">
        <location>
            <begin position="114"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="5">
        <location>
            <begin position="252"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD87579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="339" mass="37680" checksum="0CE001AF5E979E75" modified="2019-11-13" version="1">MNPLVRFFKVKLYTALFLLVLMLVIGVLGFRVISDYSWIDALYMTVITITTVGYGEVQPLDANAKLFTIFLILSSVVVLGYAITVITEYILSKNNFEEQKQRKMQKRIDGFSDHIIICGYGRNGKQAAKKLLAYGKTFVIIEKNKELMDKSQTDEIPFVLGNANEDEILIQAGIARANTLITALPNDADNLFVVLSARQMKANLTIISRASQETSYQKLKLAGADNVILPDRIGGDHMASLVVVPDLIEFIDNLAIVGKSNINIEEVPIEKLYNASSIKTIKDLDLRRKTGCTVIGYKDVNGEYIVNPEADQSLVPDSKIIVLGKPEQIQKLNSLYDIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDN8</accession>
    <name>A0A5C6ZDN8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Gfo/Idh/MocA family oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000026">
        <property type="protein sequence ID" value="TXD87314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="4"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="322" mass="35898" checksum="7666E0A5EAB548C8" modified="2019-11-13" version="1">MKTINWGIIGLGKIAHKFATDLKSVEAVKLQAVASRSAEKAAAFAKEFGAEKAYGSYEALVADTAVDAIYIATPHSFHKEHALLGLQNGKAVLCEKPLAMNLKDVETMIAVAKANNTLLMEALWTYFLPHYQYALKELSNETFGKIIKMEADFGFKPQIDMDSRVFKKSVGGGSLLDIGIYPIFAALSALGMPKDISAEATFFENGADSSTQMVFQYENDVEAHLRCSLLEETKTEAIFYCEKGIIKINSRFQEPTTVTLISEEKEETIDFGYTTNGYNFETHHFNTLLRQHKTESDVMSFDFSKKLMRLLDAVRSQIGLSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDP4</accession>
    <name>A0A5C6ZDP4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type II toxin-antitoxin system VapC family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01850">
        <property type="entry name" value="PIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PINc" evidence="1">
        <location>
            <begin position="6"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="154" mass="17704" checksum="28C315E869C70D5D" modified="2019-11-13" version="1">MKKQRIYLDTSIFGGLHDEEFKDYTEPLFERVKKSEFEIIYSNVTEQELENAPDRIRATVELLPKDSTVYVKSDIESANLAKKYIDEGVVGPTSYADCLHIAMATIHNANILISWNFKHIVNVVRIVGYNSVNIAEGYKPIDIRSPRELMTYED</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDQ9</accession>
    <name>A0A5C6ZDQ9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">TolC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_19225</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000038">
        <property type="protein sequence ID" value="TXD86787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023121521" evidence="3">
        <location>
            <begin position="20"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="340"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD86787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="448" mass="50025" checksum="E0F3E5C3FF3EF240" modified="2019-11-13" version="1">MIKKVILLAICIACQYSHAQEAPTRLSLQEAIDFALENNRTVVNAARDIDAAKAQKWETTASGLPQISATADYQNFLKQQVQVIPAEFFGGAPGEFAEVIFGTKQSASAFATLNQKIFDGSYIVALQSAKVFLQISKNAKTKTDLQVRQSVIDAYGNVLLAEESIAILNRNITVLEKNLYETNKIFENGLEEEESVEQLKITLSGVESSLNNTERLKKIAYQMLNINLGLDVYNPLLLTDTLELLTEQNRSLSLLETDENPENTVDYLIAENDTEAKALMLKLEKSKALPSLDVFINGGYTGFNNDFNFFNKEQQWFGSSLFGLNLSVPLFSSGMRNSATQRAQINLEKAKTDLEETEQRIKLQIASAKSDYQFALEDYENKKENLALAQRIEEKNQTKFFEGIGSSFELRQAQTQLYGAQQELLQAMLDVINSKTALETALNSVILN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDS9</accession>
    <name>A0A5C6ZDS9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_14640</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007492">
        <property type="entry name" value="LytTR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04397">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00850">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50930">
        <property type="entry name" value="HTH_LYTTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="4"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="HTH LytTR-type" evidence="3">
        <location>
            <begin position="142"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD87905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="244" mass="27542" checksum="C6FDC8B64EB0E256" modified="2019-11-13" version="1">MKLRAIIVEDEETSRDILKNYLGKYCPNVDILGEAANVKEALALIRNEALDLVFLDVEMPYGNAFDLLDQVGDVDFETIFVTAYNQYAMEALNAHASYYLMKPISIDDLIKAVDYVTEIKAKEEALQDTILVPKTNTVQGRITIPQQDGFEVIETAHILYCKADDNYTEIHLNNHKKKVVSKTLKYFEDILKESGFARVHKSYLVNVNEITKYVKGKGGSVILSSGQEILVSASKKSDLLSYFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDT4</accession>
    <name>A0A5C6ZDT4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Thioredoxin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_13860</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="204" mass="23132" checksum="B24C960ACEDC8FB9" modified="2019-11-13" version="1">MKHTATLDTIIAESLERAIGYPEYRRVVHDLAEAGRTSGHEKTEEMANYTKLNDSRMKRWDKTLRLSEAQVVKIKSLNSSQIWLVIAESWCGDAAHVIPVLNKITEASEYIDLKLVFRDENEALMNQFLTNGAKSIAKLIMIDKDSGEVLHSFGPRPSSATKLVNNYKTKHGSITPEFKEELQLWYNKDKGQAVISDIIELLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDU1</accession>
    <name>A0A5C6ZDU1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_17430</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000026">
        <property type="protein sequence ID" value="TXD87342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022680697" evidence="2">
        <location>
            <begin position="29"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="204"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="260" mass="29341" checksum="9E12FA491CC9DD11" modified="2019-11-13" version="1">MKILKFFKKPYFATFLATLVLFVSCSQYEDLNESENQSQIENNQVYAKKGSGNEQISGDLLFESIFFGSEDLNIDIDHINKVREFRGTLSQDELSSLDRFSGLVVAKIAKKDNSYFTSFKNDLYSKDHYRIKNALETAGSKIEESMMEIPEIRDAFLLTSEITKNIDVSQFVNSNGEFDEAGFIDAVELEYGDEVEAIIGPTFIGVWLVAALVQTVVVAVSYYVGVFVAKYTPWDKLATEGAQLSELQNDILVNDIYEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDY1</accession>
    <name>A0A5C6ZDY1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">T9SS type A sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000031">
        <property type="protein sequence ID" value="TXD87020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001842">
        <property type="entry name" value="Peptidase_M36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02128">
        <property type="entry name" value="Peptidase_M36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Por_Secre_tail" evidence="1">
        <location>
            <begin position="71"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="144" mass="15844" checksum="BC2A84F623F4F2FB" modified="2019-11-13" version="1">MADQMLTGGEDQCMIWEVFANRGLGFNASQGLDGNMEDQVEDFSLPPSGDTSLANCTSLSVQASKMDTYKIYPNPATNEINIRVTQNYGRAQVSLVDINGRSVYKQQMDLNGTVTVNFGQLQAGIYILNVNNNTININEKIIIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE74</accession>
    <name>A0A5C6ZE74_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glycine cleavage system H protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 6" type="primary">gcvH</name>
        <name evidence="6" type="ORF">ESY86_14465</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
        <text evidence="3">Binds 1 lipoyl cofactor covalently.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">The glycine cleavage system is composed of four proteins: P, T, L and H.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the GcvH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005960">
        <property type="term" value="C:glycine cleavage complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019464">
        <property type="term" value="P:glycine decarboxylation via glycine cleavage system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06848">
        <property type="entry name" value="GCS_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00272">
        <property type="entry name" value="GcvH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002930">
        <property type="entry name" value="GCV_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033753">
        <property type="entry name" value="GCV_H/Fam206"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017453">
        <property type="entry name" value="GCV_H_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11715">
        <property type="entry name" value="PTHR11715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01597">
        <property type="entry name" value="GCV_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00527">
        <property type="entry name" value="gcvH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="5">
        <location>
            <begin position="22"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-lipoyllysine" evidence="3 4">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR617453-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD88086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="126" mass="13972" checksum="A0A8BB0B1D6DF4C4" modified="2019-11-13" version="1">MNIPANLKYTKDHEWIKIDGDIATIGITDFAQGELGDIVYVEVETLDETLEVEEIFGTVEAVKTVSDLFLPLSGEIIEFNENLGDEPEKVNSDPYGAGWMIKLRFSDASQIDQLLSADAYKDLISA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZED1</accession>
    <name>A0A5C6ZED1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_13480</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="174" mass="20212" checksum="7D4D8B148DE716B2" modified="2019-11-13" version="1">MNNFAHIKPIAQYKKVGYYSMCINDNELSLFEEFIKQHTKTNEKKLDHILNWLKVIGNKYGAQTHHFRPEGETADASALPPKGVDRKPQYTAYGKKKANNLRLYCLRANEHIVFLFSGDIKTTNKAQHCPNVKNHFKLANQITKAIDNAFIDKDIVWNADFTQIECNEDFKIYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEH4</accession>
    <name>A0A5C6ZEH4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17835</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000028">
        <property type="protein sequence ID" value="TXD87175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase" evidence="1">
        <location>
            <begin position="44"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="376" mass="42957" checksum="65988DEC5457A2D0" modified="2019-11-13" version="1">MKYSLLIAIITISTIFCEKTFPQSDTTNETIVKTIQKNGLAFLKNKNINSTSIGIYKDGKMYTEHFGEIEKGKSNPPDDGTIYEIGSVTKTMTGYLVARAVLEKKIKLEDEITMYLKDDYSNLQYNGNPITIKHLLTHTSGLPMFLPMEMNGVFDKLTEDVPNEYFQLEKSYDKEKFLADLKNVTLKVAPGTTYSYSNAGAELIGYVLETVFEKNIDNLMEESYLTEYGMSNTAIELNHTQKQELVQGYWMDNETFSPNQLNTLWATGGGVKMIIMDMMHYIALQLNSKNPIVSESHKVLYEECKTFKISYFWRVWNDKYGTSYNHHGGTSGTQNWLFIFPRYDLGISIITNQSGPKTPKELSRTVNKMLKDIIEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEK2</accession>
    <name>A0A5C6ZEK2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">G-D-S-L family lipolytic protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_13710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022745667" evidence="1">
        <location>
            <begin position="21"/>
            <end position="542"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="542" mass="56517" checksum="87E5B4E888E3C6B3" modified="2019-11-13" version="1">MKLNNIWLLAILLIGFTACESDDDSLSDPLIPETQTAPSPVYTSGTADFTTFVAVGNSLTAGFSDGTLFMRGQEASFPNILAQQFALAGGGNFTQPLINDNVGGLLLAGTQIAGPRLIFNPASQTPGPVSGTPTTDITNVISGPFNNMGVPGAKSSDLLETGYGNIANLVSETANPYFIRMASTPNASVLQDALAQNPTFFSLWIGNNDVLGYAASGGESNIDSPDYDPITDQATFDGAMNAIVASLATNTPNGIIANIPNVTDAPYFTTVPFAPLSPADPDFGPQIPTLNGIFGQLNQVFAFLESQGIPNATDRQIVFSQTAASAVVIKDESLMDLSAQIEAVLNASPTFPAFVQSFGLPAAAAPIVANLFGAVYGQARQANANDLLVLPSSSIIGTVNEAQADFLQASGLPEALANQFAVEGVSLPLADKWVVIPTELTEIQNATAAFNQTINNLATQYDLAFFDVNTFFGGVASNGFQAGSAFLTADYVTGGTFSLDGVHPSPRGYAVIANQMIGLINTKYGSNLPTVNPIDYTGLYIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEN4</accession>
    <name>A0A5C6ZEN4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Thioredoxin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_16405</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022674463" evidence="1">
        <location>
            <begin position="24"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="27"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="202" mass="22305" checksum="1A2E5D798EE0B72D" modified="2019-11-13" version="1">MKKTSQLILTLAFILMCFGVSNAQKGYNIGDVATDFKLENVDGKMLSMADYPDAEGFIIIFTCNTCPYAVAYEDRIIALDKTFADKGYPVIAIMPNNPEIKPGDSMKAMKARAKAKGFTFPYLMDEGQKIYPQYGASKTPEVYVLEKTNKGGVVKYMGAIDDNYQDEQAVNKRYVEDAVNALLDGTEVPEQKTRAIGCSIKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEY1</accession>
    <name>A0A5C6ZEY1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF4270 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_13725</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025366">
        <property type="entry name" value="DUF4270"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14092">
        <property type="entry name" value="DUF4270"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="537" mass="59763" checksum="A293CA0BF7E85840" modified="2019-11-13" version="1">MKTTSIASKYLFVIGLVSTCFIACERDFADLESDIINNDNASHFGTDSNKYDVIAFTKAVNPVQTNNLPINILGVYNDPNYGTTTASFVTQMRPSTFNPTFGENVEVTSVVLTIPYFSTPTEINAEGETIYRLDSLYGSGAVNLKIFENNYFLRDFKPNSTTNESQNYYSNRDTGLDMINSGQLENQLLYEIENFVPDPSQITIEEDGEDASKLAPSLRIVLPEAFWVDKIIAKQGEPELENASNFNNYFRGLYFKVEQIGNTGSMVLLNLASTNANITINYTRPAQDADADPLEFEYAINFGPNRANFLSNDFSIPNGNATTGDENLYLKGGAGSVAEINLFNGEDLDDTAGENSFEAFKKDFVETDANGKFISQTKLVNEANLIFHVNQNLVNGQEPFRLYLYDMKNNRPLVDYFFDQANSTIPRFSRPGHLGVLERVGNEPNGEGIKYRMRITEHINNLLLRDSTNVKLGIAVSTNVNLESNAMQSDVLTTDDSDLKAPISSVLSPNGTVLYGNNTTNEAKKLYLEIFYTEPNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEZ3</accession>
    <name>A0A5C6ZEZ3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF389 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_12550</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005240">
        <property type="entry name" value="DUF389"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20992">
        <property type="entry name" value="PTHR20992"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04087">
        <property type="entry name" value="DUF389"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="71"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="94"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="169"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="192"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="220"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="264"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="363"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="492" mass="55172" checksum="DEC0D9AC24684B01" modified="2019-11-13" version="1">MSDEHKFNFSEEESQEQKEKAVEQSKDAIKKDALGLWESISLFMHNLLDFRDDTDRDATIMAIKGDIPFKGATAWILVCSIFVASIGLNADSTAVVIGAMLISPLMGPILGVGLSIAVNDIDTLKRSLINLATMIVLSLLTAFLFFALFPLNEETSELLGRTRPDIRDVLIAFFGGLALIIARTKKGTIASVIFGVAIATALMPPLCTAGYGLAVGNWSYFFGAMYLFSINTIFIALATFIVLKILRFPMQKYANSAKRKRISRVATLVAIVVMIPAIWTFLTVLQESKYERDYKDFVSNEIDANPNLWLQRKDMDVQARKLTFFFNGDVSDDMSSALQNRLKDYENINDFELIINANKTRSMDRLSESLDRAYEDLDEKDNIVAGLQKQIEALQSNITNLNKQVEANNNQVGGFSFTSLSRDAKVRFHDLEYFGYSKMLQSKDFINIDTVALANVKWSGSLNDSLRTVKEAQLSKWLKSELNLDTIIIKRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF00</accession>
    <name>A0A5C6ZF00_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Flavin oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17295</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000026">
        <property type="protein sequence ID" value="TXD87317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016646">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002563">
        <property type="entry name" value="Flavin_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01613">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavin_Reduct" evidence="1">
        <location>
            <begin position="42"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="204" mass="22592" checksum="7FA4CADF8E9F0B26" modified="2019-11-13" version="1">MIYIPNADFETFEHLYKINLVNCCSGYKSANLLGSKSVRGVENLAVFSSVTHIGSDPALLGFFCRPTSVARNTYDNIKDTGFYTINHIHAGILKDAHHTSAKYDAEISEFDKTDLLSEYKNEFHAPFVKSAPLQLAMQLEAEYPIKENGTILVIGQIKGIYVQEGLLKADGFINLSEGKVSAINGLDAYAVADSSVRFEYQRPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF57</accession>
    <name>A0A5C6ZF57_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF1835 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_11720</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="312" mass="36248" checksum="7B43EDFF8AF567A7" modified="2019-11-13" version="1">MNNQLHISKGQDLTNFLRELKIEGEILTWDEILCEGPTVAGIDSKEFIETRRQFLNDFYAIEFDEAAFTSELSKLNSKSGYTEIVLWFEYELFCHINMLAVLNLIHQREINLPIYLVCSGRVKGEKDLKGLNELSSKQLLAHYKDKIRLTEEDLELAITLWRTYCGKDHNLFKNYIVKKSSFKYMSNCLKAHLKRFPDSISGLSVIERNMLTIIDQKNVKSKHHLLGYSIYYQGYYGFSDFQLKRKIDNLALLYDETETGLKLNSKGHVALLGQHNFASEINNNMTFGGIERLDYQFNDEKNELIKINLNAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF69</accession>
    <name>A0A5C6ZF69_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Serine hydroxymethyltransferase</fullName>
            <shortName evidence="7">SHMT</shortName>
            <shortName evidence="7">Serine methylase</shortName>
            <ecNumber evidence="7">2.1.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">glyA</name>
        <name evidence="10" type="ORF">ESY86_17100</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + glycine + H2O = (6S)-5,6,7,8-tetrahydrofolate + L-serine</text>
            <dbReference type="Rhea" id="RHEA:15481"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="EC" id="2.1.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7 8">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Amino-acid biosynthesis; glycine biosynthesis; glycine from L-serine: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the SHMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.1" evidence="7"/>
    <dbReference type="EMBL" id="VORO01000025">
        <property type="protein sequence ID" value="TXD87388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="UniPathway" id="UPA00288">
        <property type="reaction ID" value="UER01023"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004372">
        <property type="term" value="F:glycine hydroxymethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019264">
        <property type="term" value="P:glycine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00378">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00051">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001085">
        <property type="entry name" value="Ser_HO-MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019798">
        <property type="entry name" value="Ser_HO-MeTrfase_PLP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039429">
        <property type="entry name" value="SHMT-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11680">
        <property type="entry name" value="PTHR11680"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00464">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000412">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00096">
        <property type="entry name" value="SHMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4 7" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="6 7 8" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SHMT" evidence="9">
        <location>
            <begin position="2"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="117"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="361"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="369"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="7 8">
        <location>
            <position position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000412-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD87388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="423" mass="46188" checksum="B39B9F85C750DCB3" modified="2019-11-13" version="1">MQRDHQIFELIEAEKERQLKGLELIASENFVSDQVMEAAGSVLTNKYAEGYPGKRYYGGCEIVDEVEQIAIDRAKTLFGAVYANVQPHSGSQANTAVFSACLNPGDKILGFDLSHGGHLTHGSPVNFSGKLYTPSFYGVTEETGVLDYDKIEEIAIKERPKMIIAGASAYSRDMDFKRFREIADKVDALLLADISHPSGLIAKGILNDPIPHCHVVTTTTHKTLRGPRGGLILMGADFDNPFGLKLKNGSLKKMSSLFDSAVFPGNQGGPLEHIIAAKAIAFGEALTDEFMRYMLQVKANASAMAKAFVDKNYDIISKGTDNHMMLIDLRNKDVTGKQAEEALGKADITVNKNMVPFDDKSPFVTSGIRIGTAAVTTRGLKESDMAAIVDFIDEVISNNQDEDKLKAISEKVNAMMRDKPLFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFA1</accession>
    <name>A0A5C6ZFA1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF4403 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_13340</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025515">
        <property type="entry name" value="DUF4403"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14356">
        <property type="entry name" value="DUF4403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="208" mass="24153" checksum="188FE60CC85764BB" modified="2019-11-13" version="1">MNYDQEATNQDILLSIPIKVSFISLKNYLNKEFKGKIISRDNSNGKRINYFKILEIDIAKSTIKKYNLELIVKLETLTTLYKSRELEISIQTFVNMDMESQKIFIETYKIDSTGKSWFANQMLKSVINTFMYRKFIKKLNIELLPIITENLMLLNAKLASKIEIKSGISVLGALNDLTVTHFEIKQKNIWIIITINGWGIIDVENLDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFD1</accession>
    <name>A0A5C6ZFD1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">tRNA (Guanine-N1)-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_11035</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023012625" evidence="3">
        <location>
            <begin position="23"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="70"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="201" mass="23660" checksum="D27BDAA096231485" modified="2019-11-13" version="1">MNFFKTLSLTILCSFCLLNSNAQDDDKDKLSLNEGTIDNQFEYLIQRSNDYQDYKVVKKTWLYTLKEHTMDSLNAVRNDLTDTKQVVERQTKEISDLKKNLNSTETDLDNTIAEKDNMALFGIPMSKGNYSMLMWIIIAVLIVLLLFFIYRFKNSNTVTKQAQLSLSETEDEFEEHRRIALEREQKVRRQLQDELNKHKNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFQ8</accession>
    <name>A0A5C6ZFQ8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD(P)H-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN_red" evidence="1">
        <location>
            <begin position="4"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="176" mass="19414" checksum="B892129E35781034" modified="2019-11-13" version="1">MKHIIAFAGSNSSDSINKQLATYAAFLVDNAEALILDLNDFTTPIYSKDLEASEGIPNNATRFLELLKTTDGIILSLAENNGAYSAVFKNLFDWLSRAEQKNWLGKPMLLMATSPGAKGGQSVLEMAMDRFPRHDANIVGKFSLPSFNENFSDGKITNEAMNTELLEEVKQFKNSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFU2</accession>
    <name>A0A5C6ZFU2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Beta-ketoacyl synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_13625</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000794">
        <property type="entry name" value="Beta-ketoacyl_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014031">
        <property type="entry name" value="Ketoacyl_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014030">
        <property type="entry name" value="Ketoacyl_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020841">
        <property type="entry name" value="PKS_Beta-ketoAc_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11712">
        <property type="entry name" value="PTHR11712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00109">
        <property type="entry name" value="ketoacyl-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02801">
        <property type="entry name" value="Ketoacyl-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00825">
        <property type="entry name" value="PKS_KS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PKS_KS" evidence="3">
        <location>
            <begin position="5"/>
            <end position="387"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="389" mass="41804" checksum="AE65A2DC8D0FE578" modified="2019-11-13" version="1">MQQPISITALSSISPLGSTPEAIWDSYLNDQHCFTEKAGVLVAQLPKALQQEIEALKHSDSKYKSLDDSVLFAIFASRQAVKNAKWNPSANFGINIGSSRGATALFEKYHEAFLKNKKAETLSSPTTTLGNISSWVAHDLQTQGPEISHSITCSTALHAILNGIAWLNAGMCGKFLVGGSEAPLTPFTIAQMQALKIYSRANPKLESSNFPNQALNPEKTENSMVLGEAAAVICLEKGEASNALAHIIGIGYATELLEHNVSLSTNADCFQRSMSMALGDLKPEDIDVIVTHTPGTIKGDQAELNAIKTLFYNSMPVLTTNKWKIGHSLGASGLLSIEMALLMLQHQKCIAVPYLASEKPEKINRIMINAVGFGGNAVSILLSRPQSAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG00</accession>
    <name>A0A5C6ZG00_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Outer membrane lipoprotein carrier protein LolA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16325">
        <property type="entry name" value="LolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029046">
        <property type="entry name" value="LolA/LolB/LppX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004564">
        <property type="entry name" value="OM_lipoprot_carrier_LolA-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35869">
        <property type="entry name" value="PTHR35869"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03548">
        <property type="entry name" value="LolA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89392">
        <property type="entry name" value="SSF89392"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022870434" evidence="1">
        <location>
            <begin position="24"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="213" mass="24221" checksum="9F0DF7B982B32EB3" modified="2019-11-13" version="1">MRKLSLVLAILVGSLSFAQSAKQAENLLNEVYNKANSYDNISIDFKYVLKNTSENINQETRGDVKMQGEKYRLNILGVTRLFDGKTLYTISPEDEEVTISSDNTEDEGTITPSKMLSFYKTGYTYKMDIVQDLKGRKIQYVKLVPIDSNSEIKQILLGIDANTKHIYNLIETGNNGTQTTLTVNSFKTNEPVSKSLFTFDKSKYQDYYINKLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG23</accession>
    <name>A0A5C6ZG23_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Esterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_13750</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000801">
        <property type="entry name" value="Esterase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00756">
        <property type="entry name" value="Esterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022882375" evidence="1">
        <location>
            <begin position="19"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="380" mass="44248" checksum="2E0538C14A500458" modified="2019-11-13" version="1">MTKVLFFFVCVLSFNLVASQVIYESLESSKLGESRDIKIQLPRGYDPESDVLYPLIIVMDGDYLFEPVVGNIDYHSYWGDMPKSIVVGINQRETRNEDLSYSAETYFPSDEGSRFFEFIGMELIPYINSKYLTSEFRIIIGHDLSANFLNFYLFKEEPLFRGYIAFSPELSPEMETRLSERLKTQTEDTFYYLATGTNDVNELKQKILQLDNSLKSVENPKLHYRFDNFEDADHYSLVGLGIPKAINEIFGLFKPINRKEYDEKMLTYEGSPYEYLMKKYEDIEFFYGFEKKVVENDIRAVAAAARKKGDLDAMKDLSKLASREYSKSMISAYYTGLYYEMDGNTKKALQNYQSGLLLTESQFITKDMLLDKIYELQDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG53</accession>
    <name>A0A5C6ZG53_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase family 4 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_09845</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="191"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="377" mass="42825" checksum="91B33D25628B58E2" modified="2019-11-13" version="1">MKKILYLSPGCFDKGGISRYNRYQIRAIREISGKNNVRVYSLLGPKAGDFEEQFKVTWHGWGATTPSKLAFTLKVLFALLFWKPDIIWLGHINLTEILVRFNLFTKVKSVLNIYGLEVWSGLRPNVERGFKKVTHVISDCHFTAKYAEDEGFRPRGTVEVIWDCVDLEKFTAEGAADNNFYEHYKLPNPIEHPWILSLGRLSFTAAHKGYERLIEVFAKVVKGDARSVLVFAGKGDMIDFLKKLAEKYNVLNRVYFSGMVHEEDLPKFYRASRVFSLVSDRGKGRGEGIPLTPLEAMACGSPIIVGNQDGSQEAIFESKNGYCISPHDLDGHAKAISAILNNQDEFEHKSKSAITIAHQYFSFQEFKSKHQTFLLKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG71</accession>
    <name>A0A5C6ZG71_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">EamA family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_11755</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88637.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="5"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="183"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="212"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="242"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="269"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="5"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="156"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88637.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="301" mass="34345" checksum="691A29CF6FAA50F5" modified="2019-11-13" version="1">MNTKYYLAVITAFSIWGFFSVVLKSLDDFSAFDILSYRTLGAATIMLVVSLLLRPKVLKNSLNLFKSLEKVDKRRIVIVNILSGLFLALNWYIFIYVMNNVSVSATSLAYLICPILTMVLAYLILKEKLFKLQWLAVTLSFTGCLLLSLGNLTNLFYSMIIALTYALYLVLQRKNQEMDRFLILTFQIGFAVLFLLPFIVTHESTTEKTNFFYVMLALIAVVFTIIPMFLNIYALRGLNSSVVGVFIYVNPLINFGLAIFYFGEKVTPVEGICYALILLSIFLFNFASLKNRIHRRRAAHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGP5</accession>
    <name>A0A5C6ZGP5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Polyribonucleotide nucleotidyltransferase</fullName>
            <ecNumber evidence="6">2.7.7.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Polynucleotide phosphorylase</fullName>
            <shortName evidence="6">PNPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">pnp</name>
        <name evidence="9" type="ORF">ESY86_09975</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n)</text>
            <dbReference type="Rhea" id="RHEA:22096"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the polyribonucleotide nucleotidyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.8" evidence="6"/>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004654">
        <property type="term" value="F:polyribonucleotide nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01595">
        <property type="entry name" value="PNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015847">
        <property type="entry name" value="ExoRNase_PH_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012162">
        <property type="entry name" value="PNPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015848">
        <property type="entry name" value="PNPase_PH_RNA-bd_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11252">
        <property type="entry name" value="PTHR11252"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03726">
        <property type="entry name" value="PNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03725">
        <property type="entry name" value="RNase_PH_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005499">
        <property type="entry name" value="PNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="SSF54791"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="SSF55666"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03591">
        <property type="entry name" value="polynuc_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6 9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 6 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="S1 motif" evidence="8">
        <location>
            <begin position="630"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="697"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="489"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="495"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD89090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="757" mass="83928" checksum="7085CF898F9DC104" modified="2019-11-13" version="1">MIPKTFREVIDLGDGREISIETGKLAKQAHGSVVVQSGKCMLLCTVVSNYEQKDLPFLPLTVDYREKFAAAGRYPGGFFKREARPSDGEVLTMRLVDRVLRPLFPKDYTAETQVMIQLMSHDDDVMPEAMAGLAASAAIQLSDFPFECAISEARVGRVNGEFVINPTRAQLLESDIEMMIGASADSVMMVEGEMDEISEEDMIEAIKFAHEAIKLQIEAQHRLADAFGRKEVREYDRAPANEDLAKQVHDMAYDKVYAVAKAGSSKKERTEAFANIKEEVKASFSEEELEAHGDLVSDYYRKAEKAAVRDLTLNEGLRLDGRKTDEIRPIWCEIDYLPSVHGSAIFTRGETQALATVTLGTSRDANQIDMPSQEGEERFYLHYNFPPFCTGEARPIRGTSRREVGHGNLAQRALKGMVPDECPYTVRVVSEVLESNGSSSMATVCAGTMALMDAGVQLKKPVSGIAMGLISDGDSGKYAVLSDILGDEDHLGDMDFKVTGTADGITACQMDIKVKGLSYEILVNALKQARDGRLHILEKLTDTIAQPNADVKAYAPKMVTRRIPNEFIGAMIGPGGKVIQELQKETGTTIVINEDPVTEEGIIEILGTDQEGIDKVLAKIDSVLFKPQVGSVYEVKVIKMLDFGAVVEYMDAPGNEVLLHVSELAWERTENVSDVVNMGDVFDVKYFGLDKRTRKEKVSRKAIMPKPEGFVERPPRDSRDSRDNNRSGGRDNRGSRDNRGRDDRRDDRKPREDKKDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGT7</accession>
    <name>A0A5C6ZGT7_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Holliday junction ATP-dependent DNA helicase RuvB</fullName>
            <ecNumber evidence="6">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">ruvB</name>
        <name evidence="8" type="ORF">ESY86_14390</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="6">Forms a complex with RuvA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the RuvB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="6"/>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00016">
        <property type="entry name" value="DNA_helic_RuvB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041445">
        <property type="entry name" value="AAA_lid_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004605">
        <property type="entry name" value="DNA_helicase_Holl-junc_RuvB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008824">
        <property type="entry name" value="RuvB-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008823">
        <property type="entry name" value="RuvB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42848">
        <property type="entry name" value="PTHR42848"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17864">
        <property type="entry name" value="AAA_lid_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05491">
        <property type="entry name" value="RuvB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05496">
        <property type="entry name" value="RuvB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00635">
        <property type="entry name" value="ruvB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5 6" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 6 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="AAA" evidence="7">
        <location>
            <begin position="54"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="62"/>
            <end position="69"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD88073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="340" mass="37513" checksum="C268F787AADCBD34" modified="2019-11-13" version="1">MNENLDPTDENFTPEELEVEKKLRPLSFDDFTGQAQILENLQIFVQAANGRNEALDHTLFHGPPGLGKTTLAHILASELNVGIKVTSGPVLDKPGDLAGLLTNLDERDVLFIDEIHRLSPIVEEYLYSAMEDYKIDIMIESGPNARTVQINLNPFTLVGATTRSGLLTAPMRARFGIQSRLQYYNTELLTTIVERSASILNVPISMEAAVEIAGRSRGTPRIANALLRRVRDFAQIKGDGTIDIKIARFALEALNVDAYGLDEMDNKILATIIDKFKGGPVGITTLATSVSESAETIEEVYEPFLIQQGFIMRTPRGREVTELAYKHLGKIKGNVQSGLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH19</accession>
    <name>A0A5C6ZH19_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Flavodoxin reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="223" mass="25139" checksum="EB1E484340A90184" modified="2019-11-13" version="1">MEQKIKLKKIEFVTHNVLRLLTEKPEGFTFKPGQATMMAIDKDGLRDEKRPFTFTNLPDDDELEFTIKVYPSHNGMTEHLPNLKVGDQLIVGDVWGAINYQGQGSFIAGGAGVTPFIAILKDLLQKDQLEGNKLFFANSEAKDIIYKNNLEAWLGEDLHCILSDEEHEAYAKGYISQKFLEKHNLDVNKNVYLCGPQPMMDAVKTDLFAMGLPKSHLVTEDGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH57</accession>
    <name>A0A5C6ZH57_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11625</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88615.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase" evidence="1">
        <location>
            <begin position="73"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88615.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="404" mass="45643" checksum="57095758FDA45EF9" modified="2019-11-13" version="1">MVIFDGTSSVGKHSINQNLHSIMKQLLVALITISILTGCKTRKQESNVVIDALPLKTYFQKSTLPAAVMGYSTKEGKMEWYAYGPSVWDGKDSITENNIFRIYSMTKAIASVAALQLVEQNLIGLDDPLAELMPEMTSIPILTKNGALIKSNTPITLRHLLTHTSGFGYEFMDERLQAFDKSEWEYEDMPRLFEAEELWLYGTSLDWVGKIIEKISGESLETYLRKNVTGPLEMNSTWFNVPENLKENIVSWGKRDSIGFQEYPRIPSTSVTDYSAGGGLFGSPKDYLTFLVCMMNDGKYDGGQILKPETVELMSSNHLPNDLSINSEGDTHGLAWAIEDSEDEILRSKGSGYWGGLANSYYSLDAEKNIALVYFTNFFPYGDKETYNFYKLFEQNVYLRNENR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHF1</accession>
    <name>A0A5C6ZHF1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Flavin mononucleotide-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_11235</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024747">
        <property type="entry name" value="Pyridox_Oxase-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12900">
        <property type="entry name" value="Pyridox_ox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="151" mass="17138" checksum="F274EA7EC6DABACD" modified="2019-11-13" version="1">MIKPLNKKQCELLLNQNYIGDLSYIYQNRPFVVPITYLYKDDRIICYSGEGHKITAMRLHEPVSIGVSEITSIKQWKSVVAHGNFEELEGPDAKALLHEFSLGVKDAILQAEHNDLNFISEFSARIKGDDIPIVFVINIDELTGRMSNDSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHJ5</accession>
    <name>A0A5C6ZHJ5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">4-carboxymuconolactone decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_09195</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004675">
        <property type="entry name" value="AhpD_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026445">
        <property type="entry name" value="AlkhydPrxdase/COmuclacdeCOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003779">
        <property type="entry name" value="CMD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02627">
        <property type="entry name" value="CMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="SSF69118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00778">
        <property type="entry name" value="ahpD_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04169">
        <property type="entry name" value="perox_w_seleSAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMD" evidence="1">
        <location>
            <begin position="23"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="111" mass="12542" checksum="49D66C800969A57A" modified="2019-11-13" version="1">MQKTYYDPADLRKFGKISDWNEELGSKFFEYYNAVFKEGKLSEREKSLIALAVAHTVQCPYCIDAYTGDGLKRGITKEEMMEALHVSAAIRGGASLVHGVQMMNKVNKLEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHK8</accession>
    <name>A0A5C6ZHK8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">3-oxoacyl-[acyl-carrier-protein] reductase</fullName>
            <ecNumber evidence="3">1.1.1.100</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">fabG</name>
        <name evidence="4" type="ORF">ESY86_10420</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a (3R)-hydroxyacyl-[ACP] + NADP(+) = a 3-oxoacyl-[ACP] + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:17397"/>
            <dbReference type="Rhea" id="RHEA-COMP:9916"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78776"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="EC" id="1.1.1.100"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.100" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004316">
        <property type="term" value="F:3-oxoacyl-[acyl-carrier-protein] reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011284">
        <property type="entry name" value="3oxo_ACP_reduc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01830">
        <property type="entry name" value="3oxo_ACP_reduc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="3" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="2 3" id="KW-0521">NADP</keyword>
    <keyword evidence="3 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="156"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="13"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="156"/>
            <end position="160"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR611284-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR611284-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="248" mass="26351" checksum="6A8729FB396CA092" modified="2019-11-13" version="1">MKLLEGKTAIITGASRGIGKGIAEVFAKHGANVAFTYSSSVEAANALEKELNTEGIKAKGYKSDASSFDESQKLAEDVLAEFGSIDILVNNAGITKDNLLMRMSEDDFDKVIEVNLKSVFNMTKAVQRSMLKQRKGSIINMSSVVGVKGNAGQTNYAASKAGIIGFSKSVALELGSRNIRSNVIAPGFIETEMTAKLDEETVKGWRNAIPLKRGGTPEDIANACVFLASDLSAYITGQTLNVDGGMLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHN8</accession>
    <name>A0A5C6ZHN8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF4412 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_08720</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025524">
        <property type="entry name" value="DUF4412"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14371">
        <property type="entry name" value="DUF4412"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022715479" evidence="1">
        <location>
            <begin position="23"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4412" evidence="2">
        <location>
            <begin position="89"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="270" mass="30642" checksum="D575CF70842F4A3C" modified="2019-11-13" version="1">MKTKHLLTAIIVFFLMFQSAEAQFLKKLKKRVEQKVENAVIEKTANKAAEKATKSMDKAFDINPFGGGAGKEKADPSLVANSYDFTWKYSLKMSTKDGEIVFDYFLNPGASYFGFTSATMDNMFTVMDNDHNIMVMFMASEGNSTGMVTQMPDVLDLEEADAESAKFTFETLPEKTINGYRCKGVKATSEDYEMLMYFTNETKVSFDDIFKNSKTKIPVELKDYFDPDDKVLMISMDMKDLKNEKQSAKMECVGLEKVSKTVNKSDYKFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHS0</accession>
    <name>A0A5C6ZHS0_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Energy-dependent translational throttle protein EttA</fullName>
            <ecNumber evidence="7">3.6.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Translational regulatory factor EttA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">ettA</name>
        <name evidence="10" type="ORF">ESY86_12035</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="7">Associates with ribosomes and polysomes.</text>
    </comment>
    <comment type="domain">
        <text evidence="7">The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.</text>
    </comment>
    <comment type="domain">
        <text evidence="7">The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="7"/>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045900">
        <property type="term" value="P:negative regulation of translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00847">
        <property type="entry name" value="EttA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022374">
        <property type="entry name" value="EttA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43858">
        <property type="entry name" value="PTHR43858"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03719">
        <property type="entry name" value="ABC_ABC_ChvD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="6 7" id="KW-0810">Translation regulation</keyword>
    <keyword evidence="2 7" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="9"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="333"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="region of interest" description="PtIM" evidence="7">
        <location>
            <begin position="251"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="43"/>
            <end position="50"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <begin position="365"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD88689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="563" mass="63698" checksum="9A26DA4CE19F1099" modified="2019-11-13" version="1">MSDDKKVIFSMSGLTKTYQSANTPVLKNIYLSFFYGAKIGILGLNGSGKSTLLKIIAGVDTNYQGDVVFSPGYTVGYLEQDPQLDDDKTVMEIVREGAAETVAILDEYNKINDQFGLEEVYSDPDKMEKLMNRQAVLQDQIDAADAWELDTKLEIAMDALRTPEGDKKIGVLSGGERRRVALCRLLLQEPDVLLLDEPTNHLDAESVHWLEHHLAQYKGTVIAVTHDRYFLDNVAGWILELDRGEGIPWKGNYSSWLDQKSKRMAQESKTASKRQKTLERELEWVRQGAKGRQTKQKARLNNYDKLLSQDQKQLDEKLEIYIPNGPRLGTNVIEANGVSKAYDDKLLYEDLNFKLPQAGIVGVIGPNGAGKTTIFRMIMGEENPDKGEFKVGETAKLAYVDQKHSNIDAEKSIWQNFSDEQELIMMGGRQVNSRAYLSRFNFSGSEQNKKVKLLSGGERNRLHLAMTLKEEGNVLLLDEPTNDLDVNTLRALEEGLENFAGCAVVISHDRWFLDRICTHILAFEGNSQVYFFEGSFSEYEENKKKRLGGDLMPKRIKYKKLVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI20</accession>
    <name>A0A5C6ZI20_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha-2-macroglobulin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_12415</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protease inhibitor I39 (alpha-2-macroglobulin) family. Bacterial alpha-2-macroglobulin subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004866">
        <property type="term" value="F:endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041246">
        <property type="entry name" value="Bact_MG10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001599">
        <property type="entry name" value="Macroglobln_a2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002890">
        <property type="entry name" value="MG2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00207">
        <property type="entry name" value="A2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17973">
        <property type="entry name" value="bMG10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01835">
        <property type="entry name" value="MG2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01360">
        <property type="entry name" value="A2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="SSF48239"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="A2M" evidence="2">
        <location>
            <begin position="1242"/>
            <end position="1332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="2023" mass="230478" checksum="739211B160E8FF54" modified="2019-11-13" version="1">MILCFANASQAQNPDYNKLWAQVLKQENEGLPKSALKIVEQIGIQAKQDDNAPQQIRVMLYKSKYALDLEEDAQLKIIQKFKAEMSTAEAPVKNVLENMLANLYWQYFQQNRYQFYNRSKTETKVDAEDFRTWDLQTLFDDIQLHFENSLKNPKILQQTPIEDFSAILTEQKGSKTYRPTLYDLLSQNALTFYTTTENSISKPAYKFEIDNPDYLKDASTFLQLKITSKDSSSLELNALKIYQDLMQFHQADASPYAFADVDIDRLNFVKSNAIFNEKDSILLNTLQKESDKWNAAKVDVAARYDFEIAKLYYQQGQEYNPTTKPEMRWKLKEAVELCNKVIKNYPNSTGAKMCQNLKAAILTQTIGFTSEKVLPSQSFSRFLVNYSNFNSVDFKAYKVDVTEISSFNQFYNSEDQLKFLKNKAVSTQWTASLKDENDYQSHSTEVEVPKLENGHYIILAKAAGTNGVFATQTLQVSDFAVIDMSSDSQMIFQIINRNNGEPQRNVSVALRFQNGYNGNFSTNKLSSDAEGFISINKSQERYMNLSLALSKNDQTGYFDGFYAYNYGRTSENKNQTSYKSFLFTDRSIYRPGQTVYFKGIAMKTERGKSSVLADEDVYVTLYNTNDEDIKELEFKTNAFGSISGEFILPNGGLNGNYYLEFDSNSGNADMFSEHYFSVEEYKRPKFETSFKPVTETFKVNDSVTLNGTALAYAGSNITDAKVVYRVTRKVQYPRWYYWYRPWFNSEPQEITHGETSTNAKGEFEISFKAQPDESVDKETLPIFNYEITADVTDLNGETRSATTIVNVGYHALVASITVAEQLDKAKKDHKLSIDTKNLNGEFVAAEGSIKIYKLQAPERVLRQRAWEAPDYQLMSAEVFINKFPHEAYEDEANPAHWKKGKLVFESTFDTAKSKDIELGKIKNWESGLYSIELESTDKFGQLVKAEARTTVFSDDDKTVADNQLFTIKTNRDSYSEDENVELTLGSAAKDLRVTVRVEKDQKLFKTFIVPLSNTKKTIAIPVTKADLGGFIITYSLAAFNSFEGAKLRINVPYPKTDLEIETITFRDKLQPGTDETWSFKIKGPKGDEVSAEVLASMYDASLDQFKPHDWSFSPIYKPQYNSGFELNARQSFGVDPFRVYNQSRNYPYYSHQSYDQLNWFGFYFGQGRNYMTRALGGRVAGVQMVADETEIEETSMLESNANLDEVVVVGYGTVEKKINAPDPKEESQNFDNIQIRKNLQETAFFFPQLQTDAEGNVSFSFSTPEALTKWKLQLLAHNKTLESTVSSMETVTQKELMVIPNAPRFLRQGDEISISTKIANLTENVLSGQAKLILTDAVSGRDITSKLLSQGNGSLLGETSTGQTEPFTVDAKGNTQVSWNLSIPNDVDAVQYKILAKAGDFSDGEQNAMPVLSNRMLVTETLPMWIRSNETRTFTLDKLKNNSSTTLKNHKLTLEMTSNPAWYAVQALPYLMEYPYDCNEQTFSRYYANALASHIANSNPRIREVFNQWASQDALISNLEKNQELKNMLIAETPWLRDAESETEQKKRIALLFDMNKMHNELTSAKRKLQNSQMNNGAWAWFNGGEPNRYITQHIITGFGHLDKLGVTSIAPDDQNAMIEKAIAYLDAEFVQEYKDIKKYDKDADLNKDHLSYTQLHYLYMRSFFPKQEKSKEVQTTIGYYQTQIRKYWLKRSLYAKGLMALAMQRMDDPNTAKKILASLKENSITSDELGMYWKSNTSSWHWYQAPIETQALMIEAFYAIEKDPKTIDNLKIWLLKNKQTNSWKSTKATTEAVYALLLQGSDWLSVTDMVDVVIGGQQIEPSKLEDVKVEAGTGYYKTSWSASEITPEMATVKLTKTGDGIAWGSLYWQYFEDLDKITSAETPLKLKKQLFKKTNTATGEEISAITAETDLNVGDLIRVRIELRSDRAMEFIHMKDMRAAGLEPVNVLSKYKYQDGLGYYESTKDASTNFFFDYLPKGVYVFEYDLRVNNAGNMSNGITTIQSMYAPEFSSHSEGVRIDVGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI66</accession>
    <name>A0A5C6ZI66_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022862740" evidence="1">
        <location>
            <begin position="21"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="161" mass="17570" checksum="3C2C327A1D2CDEF7" modified="2019-11-13" version="1">MKKVFLLAVTCIGFTLAATAQDISDNAIGLRLGDSGGFGAEVSYQRALGGNNRLEIDLGLRSGNDYDGFKLAGIYQWVWNIEGGFNWYAGAGGGLGSYSYDDRGPGNDDNETFVFVAGDIGIEYNFDFPLQLSLDARPELGFGDYRDDLDFDIALGVRYRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI93</accession>
    <name>A0A5C6ZI93_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Flavin reductase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016646">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002563">
        <property type="entry name" value="Flavin_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01613">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00903">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavin_Reduct" evidence="1">
        <location>
            <begin position="20"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="289" mass="32202" checksum="23F777603ECFF583" modified="2019-11-13" version="1">MPSFDPKVISTKTLHSHLLSSVAPRPIAFASTMDAEGRPNLSPFSYFNVFSSNPPILVFSPARRVRDNTTKHTLENSKLTKEVVINVVNYDMVHQMSLSSTDYAEGVNEFEKSGLTMLKSDMVKPYRVAESPVQFECKVNEIIELGTEGGAGNLIICEVVKFHIADEVLDDDGIIVQEKMDLVARAGGNYYSRAKKGFFEIPKPLSKLGIGVDAMPREVRESMVLTGNDLGMLGNVEALPTETEINEFINSVGERYPNIKEKTHREKHKIARNYLSYGDVESAWKLLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIJ8</accession>
    <name>A0A5C6ZIJ8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PD-(D/E)XK nuclease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038726">
        <property type="entry name" value="PDDEXK_AddAB-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12705">
        <property type="entry name" value="PDDEXK_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDDEXK_1" evidence="1">
        <location>
            <begin position="646"/>
            <end position="918"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="921" mass="106132" checksum="3C610D7E4C420194" modified="2019-11-13" version="1">MVSFIQEVIDDLQLKHSNFSKITFILPSKRAGLFLRNAIAQSINQTIFAPEIHAIEEFVEVVSDFSYTTNSELLFEFYDVYLKQTPKANIESFDKFSKWAQIIIQDFNEIDRYLIEPNHVFDYLAAIKAIENQHWSQDEQQTPYIKNYLLFWNRLKHYYKALNDALKAKQKGYQGLVYREAASNIKAYNAANQDKTYVFVGFNALNSAEELIFKELLENASADIYWDVDQSFLENPIHDAGLFTRNHKAKWPYFNNHDFNWIKSHYSEEKHIEVIGAAKQIGQIKYVGELLQQLQAEDTNLKNTALILGDESLLLPLLNSIPETIDKVNVTMGLPLHLTPMSSLFEELFRIHKKSPLLYYYKDVISLLAHPFIKPLFDTLEGNLSETLITAIKTKNIANVSLEQLQKLSTSSPEVLQLLFNSWSDQPDLAISACQKIILLLKTKFDSNKSANALPLEYLYKFHTIFNELSHLNNSFEHITSIQSLYALYRELIKKETLDFRGEPLEGLQIMGMLESRVLDYETIIITSVNEGILPAGKSHNSFIPFDVKLENKLPTYKEKDAVYTYHFYRLLQRAKHVYIIYNTEADVLSGGEKSRFITQLEIEGTHKLKQSIVAPNVPAIMQQLQKIKKTPLVIEAIDSLSKKGFSPSSLTNYIRNPIDFYYDKILGITQYKDVEESIALNTLGTVIHNTLEDFYKPYIGKLITEESILSMKSNINKTVLKHFKIEYKEGDISKGKNLIIFEIAKRYVLNFLKLELSDIKQGNTIKILAVEAENKVTIYLDSIQKSVTLRGKVDRVDQYNGMTRIIDYKTGRVDPGKVEITTWDDLLTDYTKYSKSFQVLMYAYMMAKSKQIELPVQAGIISFKNLNQGFMKFATKPSSNSRTKNQLIDEETLIAFETQLKQLITEIYNPSIDFTEKKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIV0</accession>
    <name>A0A5C6ZIV0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF3592 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08765</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021994">
        <property type="entry name" value="DUF3592"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12158">
        <property type="entry name" value="DUF3592"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="245" mass="27873" checksum="7C3EC9111794692A" modified="2019-11-13" version="1">MLSSLTQIQISGLIALLVSTPFLIKSVRNLYLTNASKQWMKVSGTIKAVSDFGKKSSLLYEYNVNRNTYKSRKLCYTNFNATQNQSASMFEKKYAQNQIVDVFYNPNNPKQAVLEPGRKDGLVPAIIILSVLFFYGCLAVFQQDVFLLFMGTYLQVVLEQNQDYASIGLNVSNLTLGLCFLNPSRGFYSRGLPRNTKNISQFIPWWLAQRLMGSTAEKWRMQIIKVIKKKSSYEDLHENTTSAVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIZ9</accession>
    <name>A0A5C6ZIZ9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DNA topoisomerase 1</fullName>
            <ecNumber evidence="8">5.6.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">DNA topoisomerase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">topA</name>
        <name evidence="11" type="ORF">ESY86_05685</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.</text>
            <dbReference type="EC" id="5.6.2.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the type IA topoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.1" evidence="8"/>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003917">
        <property type="term" value="F:DNA topoisomerase type I (single strand cut, ATP-independent) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00186">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03363">
        <property type="entry name" value="TOPRIM_TopoIA_TopoI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00952">
        <property type="entry name" value="Topoisom_1_prok"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000380">
        <property type="entry name" value="Topo_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003601">
        <property type="entry name" value="Topo_IA_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023406">
        <property type="entry name" value="Topo_IA_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013497">
        <property type="entry name" value="Topo_IA_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013824">
        <property type="entry name" value="Topo_IA_cen_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013825">
        <property type="entry name" value="Topo_IA_cen_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013826">
        <property type="entry name" value="Topo_IA_cen_sub3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023405">
        <property type="entry name" value="Topo_IA_core_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003602">
        <property type="entry name" value="Topo_IA_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005733">
        <property type="entry name" value="TopoI_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028612">
        <property type="entry name" value="Topoisom_1_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025589">
        <property type="entry name" value="Toprim_C_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034149">
        <property type="entry name" value="TOPRIM_TopoI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42785">
        <property type="entry name" value="PTHR42785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01131">
        <property type="entry name" value="Topoisom_bac"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13368">
        <property type="entry name" value="Toprim_C_rpt"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00417">
        <property type="entry name" value="PRTPISMRASEI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00437">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00436">
        <property type="entry name" value="TOP1Bc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56712">
        <property type="entry name" value="SSF56712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01051">
        <property type="entry name" value="topA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00396">
        <property type="entry name" value="TOPOISOMERASE_I_PROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 8 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0799">Topoisomerase</keyword>
    <feature type="domain" description="Toprim" evidence="10">
        <location>
            <begin position="3"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with DNA" evidence="8">
        <location>
            <begin position="163"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="812"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="816"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-tyrosine intermediate" evidence="8">
        <location>
            <position position="284"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="8">
        <location>
            <position position="33"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="8">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="8">
        <location>
            <position position="140"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="8">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="8">
        <location>
            <position position="148"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="8">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="8">
        <location>
            <position position="286"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="8">
        <location>
            <position position="473"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD90228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="852" mass="95839" checksum="54C90484AFDACC4E" modified="2019-11-13" version="1">MPKNLVIVESPAKAKTIEKFLGKDYKVESSFGHIADLPSKELGVDVEGDFAPKYQVSKDKKDIVKKLKELAKKADMVWLASDEDREGEAIAWHLAESLNLDKAKTKRIVFHEITKSAIQKAIENPRGIDYDLVDAQQARRVLDRIVGYELSPVLWRKVKGGLSAGRVQSVSVRLIVERERDIQNFTAEASYRIDAEFSNEDGQSFKAKLPKNFSTKEEAYKFLEDNAKAEFKVADLQKKPAKKSPAAPFTTSTLQQEAARKLGYSVGRTMSNAQRLYEAGLITYMRTDSVNLSEEARKGAQAEIESAYGSKFSKPRTYKGKSKGAQEAHEAIRPTDFNTHSVNIERDQARLYDLVWKRAIASQMSDAQLERTNVKIEASTHAETFTANGEVIKFEGFLKVYLEGTDDEDTEQDGMLPAMKVNETLLNSCITATQRFSRPPYRYTEASLVKQLEELGIGRPSTYAPTISTIQNRNYVDKGANEGVERDYTQLTLQEGNIKDKTLTEKTNSDKGKLIPTDIGMIVTDFLVTHFGGILDYNFTAKVEADFDQIAEGKEDWKKMMKNFYKEFHPRVEDVQENAERESGERILGKDPKTGKQVSVRLGKFGPMVQIGTVDDEEKPQFASLSPDQQLTSITYEEAMELFQLPKQLGTYEGENVEVNNGRYGPYVKHGEIFVSLPAGTNPVDVEKDVAIELIKEKQKADAPIYMFQDLPVQKGKGRFGPYIKWNNMFINVNKKYDWDDLSDDDIVELIETKIQKEKDKVIHNWEAEGVRVEKARWGRHNIIKGKTKVELPKTVDVSDMTLEAAMAELAKKAPKKKAAAKKKGAKTAKKSTAKKTSTTKKAGSKKSSSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ49</accession>
    <name>A0A5C6ZJ49_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_09840</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="211" mass="23331" checksum="F8D29B0E78108CD0" modified="2019-11-13" version="1">MIKLVKQLVESFIRNIGGVFGIKLRYLYYKHQFKTCGSKIIIEPGVFFENAEFMVFGSNIWIDKNVILVGGAFNSTGRNFSQKGKTLVKWGELNISDGVHIAPFTLIQAHGGVKIGKNVTVASGSKIYSLSHHYKNLENLKDTKRYSFSSMANLEDQYMIIGNVIVGDYAAIGLNSVILPGSYIPNGTWVSVMSTVNSSDQMLSNSVFKSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJC5</accession>
    <name>A0A5C6ZJC5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">ATP synthase subunit c</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">ATP synthase F(0) sector subunit c</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">F-type ATPase subunit c</fullName>
            <shortName evidence="13">F-ATPase subunit c</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Lipid-binding protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13 15" type="primary">atpE</name>
        <name evidence="15" type="ORF">ESY86_07760</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.</text>
    </comment>
    <comment type="function">
        <text evidence="13">Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cell membrane</location>
            <topology evidence="13">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the ATPase C chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045263">
        <property type="term" value="C:proton-transporting ATP synthase complex, coupling factor F(o)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01396">
        <property type="entry name" value="ATP_synth_c_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005953">
        <property type="entry name" value="ATP_synth_csu_bac/chlpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000454">
        <property type="entry name" value="ATP_synth_F0_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020537">
        <property type="entry name" value="ATP_synth_F0_csu_DDCD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038662">
        <property type="entry name" value="ATP_synth_F0_csu_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002379">
        <property type="entry name" value="ATPase_proteolipid_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035921">
        <property type="entry name" value="F/V-ATP_Csub_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00137">
        <property type="entry name" value="ATP-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00124">
        <property type="entry name" value="ATPASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81333">
        <property type="entry name" value="SSF81333"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01260">
        <property type="entry name" value="ATP_synt_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00605">
        <property type="entry name" value="ATPASE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 13" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="13" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 13" id="KW-0138">CF(0)</keyword>
    <keyword evidence="6 13" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8 13" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 13" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 13" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_C" evidence="14">
        <location>
            <begin position="5"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="site" description="Reversibly protonated during proton transport" evidence="13">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TXD89669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="63" mass="6164" checksum="136553704643ADBE" modified="2019-11-13" version="1">MYNLIGAGLIVIGAGIGLGQIGGKAMDGIARQPEASGKIQTAMIIVAALLEGLAFGALILGQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJC9</accession>
    <name>A0A5C6ZJC9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_10345</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024671">
        <property type="entry name" value="Atg22-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11700">
        <property type="entry name" value="ATG22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="62"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="97"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="6">
        <location>
            <position position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD89157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="171" mass="19354" checksum="30BEC00A0105FA22" modified="2019-11-13" version="1" fragment="single">MYQPKKGSKKLLNAWAFYDWANSVYTLTIASSIFPIFYSALFVDQVEKQVSAFGMVFKSTALITYVTAFTFLIVSFSSPILSGIADYVGNKKNFMKFFCYLGGIGCIGLYWFSLENIHISLLFYFMGLLGYWGSLVFYNSYLPDIAYPEQQDRISAKGFSMGYLGSVLLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJM3</accession>
    <name>A0A5C6ZJM3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_06190</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="418" mass="47416" checksum="7432C68ABD56110D" modified="2019-11-13" version="1">MVLILLFVALLYWSVSSTSKTFGRSKILSPKNSETVNFKLYDSVLIAASTNYNSNLVKNLMQGEQYRKAWSEPVAVQILFLDTLFGGGVKILEEGGGNQTHSLKLEGPNGIEYSLRSVNKDPTPLIPDIAYTLGLKNIVVDGIAAQHPFGALLASQLAEAANIPHTHPKMVFLPKQDFLKDYNEKYGNRLFLLEYESDSWVDWTKFDSITEIRDTEDLQKLKMEQGSHLSIDKRALIKARLFDFLIGDWDRHTKQWGWAIKKIDSNYLAIPIPGDRDNAFFNAEGIIPSILGHPMIIPTLRSFDDKIDFMEGLVYPFDRYFLIDTPESIFTAEAKALQKLMTNETIDASLNVWPKSIAKLNGSEITRKIKQRRDDLVKYAKEFKAEIDRQGIVTEALKGSEDNKLNPKLLKCFDCNRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJN2</accession>
    <name>A0A5C6ZJN2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Rhomboid family intramembrane serine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_11480</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="SSF144091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="74"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="192"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="Rhomboid" evidence="6">
        <location>
            <begin position="41"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD88850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="216" mass="23950" checksum="6D30C4C333AECA8C" modified="2019-11-13" version="1">MGNLSIVLIVIIAANALISYKGFNDYGFFEKYKFNVGRIRAGEQFRMFSSGFLHADTTHLLFNMLTLFFFADRVIFFVGSVNFLVIYVASLLLGSVLSFYFHKEESQYSAVGASGAVTGILYAAILLDPRMSLYMFFIPIPIPAYVFGIGYLLYSIYGMKNRVGNIGHDAHFGGAIGGFVITLIMVPSLFQTDLLMVGLLSVPIIILFVMHKTGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJP4</accession>
    <name>A0A5C6ZJP4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="12">M48 family metallopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">ESY86_03450</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7 8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7 8">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the peptidase M48 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07343">
        <property type="entry name" value="M48A_Zmpste24p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027057">
        <property type="entry name" value="CAXX_Prtase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001915">
        <property type="entry name" value="Peptidase_M48"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032456">
        <property type="entry name" value="Peptidase_M48_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01435">
        <property type="entry name" value="Peptidase_M48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16491">
        <property type="entry name" value="Peptidase_M48_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 8" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 7 8" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="100"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="286"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="328"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M48_N" evidence="11">
        <location>
            <begin position="33"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M48" evidence="10">
        <location>
            <begin position="206"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="277"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="358"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="276"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="280"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="354"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR627057-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR627057-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF16491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TXD90434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="410" mass="46425" checksum="3AFDD12F19220EEE" modified="2019-11-13" version="1">MNAQTLFYIIIGIIILNFIIDKVLDALNAKQYNDPIPKELEDVYDAEAYKKSQAYKKTNYKFGILSSLFSLLLTLGFLLLDGFEYVDNIARSFSANPILIALIFFGIIMIGSDIIATPFSVYKTFVIEEKFGFNKTTVNTFILDKIKGLLMTVIIGGGILALIVWFYQVTQDQFWLYTWGFVTVFTVFTNLFYSRLIVPLFNKQKPLEDGSLRDKISEYAKSVGFQLDKIFVIDGSKRSTKANAYFSGFGSEKRVTLYDTLVNDLDEEEIVAVLAHEVGHYKKKHIIFNLAASLLLTGLTLYILSIFISNPLLSNALGVEIPSFHVGLIAFGLLYAPISELTGLMMNHLSRKFEYQADDYAKNTYRAEPLLSSLKKLSKNSLSNLTPHPAYVFMHYSHPTLLQRALNLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJV7</accession>
    <name>A0A5C6ZJV7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Acetyl-CoA C-acyltransferase</fullName>
            <ecNumber evidence="7">2.3.1.16</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_03775</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.16" evidence="7"/>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003988">
        <property type="term" value="F:acetyl-CoA C-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00098">
        <property type="entry name" value="THIOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase_N" evidence="5">
        <location>
            <begin position="6"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase_C" evidence="6">
        <location>
            <begin position="272"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="3">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="350"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD90494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="397" mass="42917" checksum="E9FACE1C45DBD22F" modified="2019-11-13" version="1">MNKQAYIVKAYRTAVGKSKKGVFRFKRADELGAEVIQYMMKELPDLDVKRIDDVMVGNAMPEGSQGLNMARFISLIGLNSVDVPGVTVNRFCSSGIETIGMASAKIQAGMADCIIAGGSESMSSVPMTGFKPELNYNTVKAGHEDYYWGMGNTAEAVAKQFKVSREAQDEFAYHSHMKALKAQAEDRFQDQIVPIEVDETYVDDQGKKQTRSYTVTKDEGPRKGTSIEALSKLRPVFAANGTVTAGNSSQTSDGAAFVLVMSEDMVKELNLEPIARLVSYTAVGVEPRIMGIGPVKAVPKALKQAGLKQSDLELIELNEAFASQSVAVIRELDLNQDIVNVNGGAIALGHPLGCTGAKLSVQLFDEMRKRNLKDKFGAVTMCVGTGQGACGIFEFLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJZ1</accession>
    <name>A0A5C6ZJZ1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sorbosone dehydrogenase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10785</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012938">
        <property type="entry name" value="Glc/Sorbosone_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011041">
        <property type="entry name" value="Quinoprot_gluc/sorb_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07995">
        <property type="entry name" value="GSDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50952">
        <property type="entry name" value="SSF50952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GSDH" evidence="1">
        <location>
            <begin position="180"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="422" mass="46758" checksum="E0AE5CA7E7BE8EBC" modified="2019-11-13" version="1">MKYTAICMLSLFMLMACKEKVSEAKKDELAQAGTTTVETAIGSLELVAPFSSESVTNSSKVIAWPKDKTPTAPEGFAVNRFADSLEHPRWTYLAPNGDYFVSEANTRNSANQIRLLRDRDKDGVAEERHVFLKDLNQPFGMLILNGYFYVANTDGLYRYPYKEGQTEMTAEGEKIVELSASGYNNHWTRNIISNKAGDKIYISVGSASNVGEQGMEKEERRANILEVNPDGSGEIIYATGLRNPVGMDWNPVTGELWTAVNERDKLGNNLVPDYLTSVKKGGWYGWPYSYYGQIKDPRWADDPHDSLVQQAIMPDVPLGNHTASLGLTFYTNSAFPQQYKNGAFVGQHGSWNRDPLSGYKVVFVPFENGKPQPPQDFLTGFIANEIASEVYGRPVGVTVAADGALLVNDDDAGIIWRVSSEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJZ4</accession>
    <name>A0A5C6ZJZ4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">T9SS type A sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023130516" evidence="1">
        <location>
            <begin position="32"/>
            <end position="1124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1124" mass="121414" checksum="5F1EC1CB6D1F7915" modified="2019-11-13" version="1">MNVKITPRFLKLNPLYFSFFAVFLLASASLAAQTVTDIFPTRVTTKSVITITGSGFTTTTKDNIRLTGIDITKQTLVTPEVMTFEISEDNGADITESLTFNGGAVTFATGADNNINYIAPKPESLTNSKSYFVEEIYTNWDFDGDGTHFWRSDDYNSSIKNTWPNDKHELLGFKMHDGPIFSTGVDDEELTANLEDADKNGPDGYVLSRFKAYSTNGVEGKTNGGHYILTGDLIDGKVGSDEDDTDNDLATLTEIAGLTIFDVIIDGINGLELGTGISNFNRDNSVKFYSGNGKQGTFNDIEPDLLITQIAQAGGTDIYFYADEFGNVVGTPIKLSIAESNSTKIAEWRLDLFRFPGSQPIVSTKPNKRGFTSNDNEDRPIRMIAFKLEDFDINDDPSSTGYIEDIININLLAGGTADMAFLAYNAGTFDIKSPVANPLLSRFVCKIDGSSDVLFEVNAGVDNGSGGIATPATGADPNEILSYEWLKYNLPEPANTNASFLVEDVIDEDLATYKVKISNDGGTIILPVTLSQGGTPYTWNGSGWSSSYGTVAVEERGLVFASDYNDDLLALDANIDLEACDCQVASGVSVTIPPEKTLKLYGSLTVGAAIAEDVAAGISALPAGTFTLEDSASLIQTKTVTSNQNTDAIIVKRIADDLAANDYVYWSSPVVGGTLGSIPGNATYLWNPTLVNTNSTVGNWVSASGIMTQGKGYIKRVGSSSVPNDRAIFTGIPTNGPISIPIKLTSETGSSAMTEGDKHWNLIGNPYPSAISAEKFLLANVGIVQENTNPNNAAIEGGVYLWSHKSSAASANNNPFYENFGYNYNAADYEVTNGLTSTDDNFNGNIASGQGFFVKALDDDDVIFNNAMRHKGAEGSEEAYENTDFYRTTNEEVASVSADTEKQLLWLALTNEANVATVAVIGYAEGATYGKDILYDAPHMGNNDFCLYTKLADQRIVIQGRPLPFDTEDTVALGIAVPQNGIYKIAIDNLKGNVFVDQAQAIYLEDTYLNLVHDLRAAPYGFTAVTGAVNDRFVLRYTPSETLAVNENIASETFAFIKNSELQVRSSQAISGIQIYDLNGKQIATYEPNTNNRAFNANFQFARGVYLAVITLDNDLVVKTKLMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK21</accession>
    <name>A0A5C6ZK21_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PA2169 family four-helix-bundle protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06805</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011971">
        <property type="entry name" value="CHP02284"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019052">
        <property type="entry name" value="DUF2383"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016920">
        <property type="entry name" value="UCP029477"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09537">
        <property type="entry name" value="DUF2383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029477">
        <property type="entry name" value="UCP029477"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02284">
        <property type="entry name" value="TIGR02284"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2383" evidence="1">
        <location>
            <begin position="7"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="151" mass="17061" checksum="D1868BC7F5F9A396" modified="2019-11-13" version="1">MDNTKEISKKVNALIEKNNDADKGYQKAAKNAEHKDLVTFLSHQANERKTFALELTSGLKSYNPEFDVDTDGSATGAMHRTWMDVKAALSMDDDESLLEECIRGDKASKEEYEEFLEDYPALSADLRSTVQNQLTKINATLNRVKRLEDLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK41</accession>
    <name>A0A5C6ZK41_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_05315</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="220" mass="25351" checksum="6CBEFEC8DBCE3DBA" modified="2019-11-13" version="1">MDNPSKITEGGVEYSLGKFDGKSILYDFPKILIYLNAKGKLLFGEKFRIYDEDKDILMKLCSYFIKDKDNCKTFGIDTDKGILLSGPVGCGKTSLMKLLRHIVPMQRPYEMIPCRNVTFGFNHLGFKTVEEYGNTKFYCFDDLGVEPAGRFYGKDLNVMGEVLLSRYELYLDTKHKIKTHATTNLNAEELEERYGNRVRSRMRELFNLIAFEAKAGDKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK51</accession>
    <name>A0A5C6ZK51_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA pseudouridine synthase A</fullName>
            <ecNumber evidence="4">5.4.99.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridine(38-40) synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridylate synthase I</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA-uridine isomerase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 9" type="primary">truA</name>
        <name evidence="9" type="ORF">ESY86_04240</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 7">
            <text>uridine(38/39/40) in tRNA = pseudouridine(38/39/40) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:22376"/>
            <dbReference type="Rhea" id="RHEA-COMP:10085"/>
            <dbReference type="Rhea" id="RHEA-COMP:10087"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="EC" id="5.4.99.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 7">Belongs to the tRNA pseudouridine synthase TruA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.12" evidence="4"/>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106029">
        <property type="term" value="F:tRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02570">
        <property type="entry name" value="PseudoU_synth_EcTruA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.660">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00171">
        <property type="entry name" value="TruA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001406">
        <property type="entry name" value="PsdUridine_synth_TruA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020097">
        <property type="entry name" value="PsdUridine_synth_TruA_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020095">
        <property type="entry name" value="PsdUridine_synth_TruA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11142">
        <property type="entry name" value="PTHR11142"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01416">
        <property type="entry name" value="PseudoU_synth_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001430">
        <property type="entry name" value="tRNA_psdUrid_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00071">
        <property type="entry name" value="hisT_truA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="PseudoU_synth_1" evidence="8">
        <location>
            <begin position="8"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="PseudoU_synth_1" evidence="8">
        <location>
            <begin position="146"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4 5">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 6">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001430-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001430-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD90584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="246" mass="28182" checksum="FCF991F865AB508D" modified="2019-11-13" version="1">MRYFIELSYNGTAYHGWQNQPNAITVQQVLEETLSTLFQQDIAIVGAGRTDAGVHASQMFAHFETALEFPENLIFKLNSFLPDDIAVHDIFEVQANAHARFNALSRSYCYKISTKKNVFNTHLAYALHHELEVSKMIQACEILMQYKDFQCFSKSKTEVKTYNCDIMQASWEQSADELVFTIKADRFLRNMVRAIVGTLINIGAGKLEVEQLHEIIKSKDRSEAGFSVPAHGLYLFHIEYSEQIRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK53</accession>
    <name>A0A5C6ZK53_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PRC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030077">
        <property type="term" value="C:plasma membrane light-harvesting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045156">
        <property type="term" value="F:electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019684">
        <property type="term" value="P:photosynthesis, light reaction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014747">
        <property type="entry name" value="Bac_photo_RC_H_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027275">
        <property type="entry name" value="PRC-brl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011033">
        <property type="entry name" value="PRC_barrel-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05239">
        <property type="entry name" value="PRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50346">
        <property type="entry name" value="SSF50346"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PRC" evidence="1">
        <location>
            <begin position="24"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="247" mass="29349" checksum="1A0D190B2653DC83" modified="2019-11-13" version="1">MTKEEKHLYNMNELSDYKISDGFPDVRGWDVKDNDNRIIGKVDQLLVSKEAERVVYLDVEVDQSIIDAKHDPYMRSSKGSVREFLNKEGENHIIIPIGLVDLDSDSKFVHTSSIDHKTFAETKRHRQGENVDRNYETQVLESYVRKNDRIEDQQEGSSKNELLGDMTEDRLRKIVRDEIKKYHENLSKEDKVIPQRHFSDDVDDVVMMTDEEMRVNKSEHHSDWDDDGFYERREFDDDRFRKRNYNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK59</accession>
    <name>A0A5C6ZK59_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_05425</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043869">
        <property type="entry name" value="DUF5829"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19147">
        <property type="entry name" value="DUF5829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="309" mass="35923" checksum="DF4EFB1A02CCF531" modified="2019-11-13" version="1">MKTKYIQVTFLVIIFLAGCKEQKKMPEEPLIDKDKIQAMFNKNPNNVLFNHFYIVLDSSTYSQFRSNAFLKESYAGLDSGMPDFNEINDTVNAIYLRGETHYLEILRPNNSFKEPVDQIGIGFSLGGQKPFSINNSLELKEDNTKFLRASDTASFTIKDKKHTWYKAFYTVGMKTNLYTWYSYYNPEFLEAIDGEKRDNYNREDFLKKAYVPEKLFKNVVSITLNCNLADHYRFAKELELLGCSLEKKEGDDLIFKVGDIYIKLILSQYKGKSEIIQMETTLNQEDNRTIEIGAITIKTEGKKSLWTFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK92</accession>
    <name>A0A5C6ZK92_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Usp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08865</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="1">
        <location>
            <begin position="3"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="89" mass="10775" checksum="AF84313E05BF3DDE" modified="2019-11-13" version="1">MDKRILLLTDFSENAFNAVRYALKLYSDRKCNFDFLHAYQLEGYSMHNPPYNPEAFQESHEIEKRKSEKEFEKLMKMIRLHPDNPKTYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKE9</accession>
    <name>A0A5C6ZKE9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_04750</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="89" mass="10483" checksum="AE638F69E5BFD39F" modified="2019-11-13" version="1">MNAFWFNLPIHNIEKSKRFYTEIGFINNESYQDDGSASFFIGEHKFVMMLFQHEQFQPMLGNGITDTDKSNEVLFNLNANSNRRLMILQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKG4</accession>
    <name>A0A5C6ZKG4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Urocanate hydratase</fullName>
            <shortName evidence="9">Urocanase</shortName>
            <ecNumber evidence="4 9">4.2.1.49</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">Imidazolonepropionate hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">hutU</name>
        <name evidence="13" type="ORF">ESY86_01830</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>4-imidazolone-5-propanoate = H2O + trans-urocanate</text>
            <dbReference type="Rhea" id="RHEA:13101"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17771"/>
            <dbReference type="ChEBI" id="CHEBI:77893"/>
            <dbReference type="EC" id="4.2.1.49"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
        <text evidence="9">Binds 1 NAD(+) per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Amino-acid degradation; L-histidine degradation into L-glutamate; N-formimidoyl-L-glutamate from L-histidine: step 2/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the urocanase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.49" evidence="4 9"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00379">
        <property type="reaction ID" value="UER00550"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016153">
        <property type="term" value="F:urocanate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019556">
        <property type="term" value="P:histidine catabolic process to glutamate and formamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019557">
        <property type="term" value="P:histidine catabolic process to glutamate and formate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00577">
        <property type="entry name" value="HutU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023637">
        <property type="entry name" value="Urocanase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035401">
        <property type="entry name" value="Urocanase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038364">
        <property type="entry name" value="Urocanase_central_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023636">
        <property type="entry name" value="Urocanase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035400">
        <property type="entry name" value="Urocanase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035085">
        <property type="entry name" value="Urocanase_Rossmann-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036190">
        <property type="entry name" value="Urocanase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12216">
        <property type="entry name" value="PTHR12216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01175">
        <property type="entry name" value="Urocanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17392">
        <property type="entry name" value="Urocanase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17391">
        <property type="entry name" value="Urocanase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001423">
        <property type="entry name" value="Urocanate_hydrat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111326">
        <property type="entry name" value="SSF111326"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01233">
        <property type="entry name" value="UROCANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0369">Histidine metabolism</keyword>
    <keyword evidence="7 9 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 9" id="KW-0520">NAD</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Urocanase_N" evidence="11">
        <location>
            <begin position="89"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="Urocanase" evidence="10">
        <location>
            <begin position="218"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="Urocanase_C" evidence="12">
        <location>
            <begin position="454"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="130"/>
            <end position="131"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="208"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="273"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="400"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="604"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF17391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF17392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TXD90727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="682" mass="76366" checksum="426FB198F9CAAD6E" modified="2019-11-13" version="1">MHTSRLHFKDQVQEGIPTRLPDARPYDDSINHAPIRKAILTAEEKKLALRNALRYFEKQQHETLLPEFKAELDTYGRIYMYRFRPDYKMYARPIEAYPAKSRHAAAIMLMIQNNLDPEVAQHPHELITYGGNGAVFQNWGQYRLTMQYLSEMNDEQTLAMYSGHPMGLFPSHKDAPRVVVTNGMMIPNYSKPDDWEKFNALGVTQYGQMTAGSYMYIGPQGIVHGTTITVLNAFRKLNKSPKGHLFVTSGLGGMSGAQPKAGSIAGCITVCAEVNPKITQVRLDQGWIDEKITDLNALVTRVKKAKNHKETVSLAYLGNIVNVWEKFSEANLHIDIGSDQTSLHNPWAGGYYPAALSFEEANIMMAQDPEQFKIKVQESLRRQVAAINKHTAKGTYFFDYGNAFLLEASRAGARVYKDSNEKFVDKDTLVSLGESTEHWAYPSYVQDIMGPMCFDYGFGPFRWVCASGKPEDLAKTDAIACEVLETIKKNSPEEIQQQMTDNIQWIKGAQENKLVVGSQARILYADAEGRLKIAEAFNNAIKNSEIGMVILGRDHHDVSGTDSPYRETSNIYDGSQFTADMAIQNVIGDSFRGATWVSIHNGGGVGWGEVINGGFGMVLDGTDDADRRLKSMLFWDVNNGISRRSWARNEPAVFAIKRAMTREPLLKVTLPNSVDEKLLDAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKM8</accession>
    <name>A0A5C6ZKM8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_02680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004441">
        <property type="entry name" value="rRNA_MeTrfase_TrmH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46429">
        <property type="entry name" value="PTHR46429"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SpoU_methylase" evidence="1">
        <location>
            <begin position="25"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="177" mass="19882" checksum="3D6566CF89315CF2" modified="2019-11-13" version="1">MRKLKNEELDRLEVAEFKTAEKTPIIIVLDNIRSLNNIGSVFRTSDAFLIEKIYLCGITATPPHNDIRKTALGSTETVAWEYAEHTLEVIKNLKKDKVHICAIEQAEHATMLNDFKPQQQTRYALVFGNEVKGVAQDVVDASDTVLEIPQFGTKHSLNISVSCGVVVWDVFSKLQLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKY2</accession>
    <name>A0A5C6ZKY2_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">3-hydroxyanthranilate 3,4-dioxygenase</fullName>
            <ecNumber evidence="3">1.13.11.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">3-hydroxyanthranilate oxygenase</fullName>
            <shortName evidence="3">3-HAO</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">3-hydroxyanthranilic acid dioxygenase</fullName>
            <shortName evidence="3">HAD</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">nbaC</name>
        <name evidence="4" type="ORF">ESY86_05945</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 3">Catalyzes the oxidative ring opening of 3-hydroxyanthranilate to 2-amino-3-carboxymuconate semialdehyde, which spontaneously cyclizes to quinolinate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>3-hydroxyanthranilate + O2 = (2Z,4Z)-2-amino-3-carboxymuconate 6-semialdehyde</text>
            <dbReference type="Rhea" id="RHEA:17953"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:36559"/>
            <dbReference type="ChEBI" id="CHEBI:77612"/>
            <dbReference type="EC" id="1.13.11.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="3">Binds 2 Fe(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from L-kynurenine: step 3/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the 3-HAO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.6" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00330"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000334">
        <property type="term" value="F:3-hydroxyanthranilate 3,4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008198">
        <property type="term" value="F:ferrous iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034354">
        <property type="term" value="P:'de novo' NAD biosynthetic process from tryptophan"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043420">
        <property type="term" value="P:anthranilate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019805">
        <property type="term" value="P:quinolinate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006569">
        <property type="term" value="P:tryptophan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06123">
        <property type="entry name" value="cupin_HAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00825">
        <property type="entry name" value="3_HAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010329">
        <property type="entry name" value="3hydroanth_dOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15497">
        <property type="entry name" value="PTHR15497"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06052">
        <property type="entry name" value="3-HAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03037">
        <property type="entry name" value="anthran_nbaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 3" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="3">
        <location>
            <position position="47"/>
        </location>
        <ligand>
            <name>O2</name>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD90275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="177" mass="20500" checksum="55C1D9B52C501868" modified="2019-11-13" version="1">MSKLYSPINFKAWIEENRHLLKPPVGNKVVWKDGDFIVMVVGGPNNRKDYHYNETPEFFYQVEGDIVLKVIDEGEPKDIHIKEGEIFLLPPKVPHSPQRGANTVGLVIEYKRPDGMKDALLWYCENCTTKLYEEDFSVEDIETDMPKIFDKYYGDTDKRKCPNCGEVMQAPKKVQVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKZ3</accession>
    <name>A0A5C6ZKZ3_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Putative pterin-4-alpha-carbinolamine dehydratase</fullName>
            <shortName evidence="4">PHS</shortName>
            <ecNumber evidence="4">4.2.1.96</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">4-alpha-hydroxy-tetrahydropterin dehydratase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Pterin carbinolamine dehydratase</fullName>
            <shortName evidence="4">PCD</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_03865</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>(4aS,6R)-4a-hydroxy-L-erythro-5,6,7,8-tetrahydrobiopterin = (6R)-L-erythro-6,7-dihydrobiopterin + H2O</text>
            <dbReference type="Rhea" id="RHEA:11920"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15642"/>
            <dbReference type="ChEBI" id="CHEBI:43120"/>
            <dbReference type="EC" id="4.2.1.96"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the pterin-4-alpha-carbinolamine dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.96" evidence="4"/>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008124">
        <property type="term" value="F:4-alpha-hydroxytetrahydrobiopterin dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006729">
        <property type="term" value="P:tetrahydrobiopterin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00434">
        <property type="entry name" value="Pterin_4_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036428">
        <property type="entry name" value="PCD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001533">
        <property type="entry name" value="Pterin_deHydtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12599">
        <property type="entry name" value="PTHR12599"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01329">
        <property type="entry name" value="Pterin_4a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55248">
        <property type="entry name" value="SSF55248"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 5" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="96" mass="11205" checksum="83FBF74AC43999CC" modified="2019-11-13" version="1">MSKLSNEVIEKKLLQFPDWELKDDTLYAEFEFENFKDCFSAMSRIAFECEAQNHHPNWSNVYNLLKISLSTHDADGVTQKDFDLAEAIEEIVEVED</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLC9</accession>
    <name>A0A5C6ZLC9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MBL fold metallo-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06175</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="34"/>
            <end position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="253" mass="29311" checksum="0172E31585780DBD" modified="2019-11-13" version="1">MKIRFLGTGTSQGIPVIGSEHPVCLSNDTKDKRLRVSVLVEWDEFKYVIDCGPDFRQQMLRANCTKINGIVFTHEHADHTAGLDDIRPFYFRQGDIPFYAHKRVLGELTKRFDYIFTSKDKYPGVPSVIQHEIKNEPFTLGNIEVMPINGYHHKLQVFGFRFAEFAYLTDMKTVATEEREKLKGVKVLVINALRETEHISHFNLQEALEFIEDVNPERAYLTHISHFLGFHEDVQKKLPKNVFLAYDNLQIAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLE1</accession>
    <name>A0A5C6ZLE1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03665</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="80" mass="9300" checksum="DEED487D731B8E1F" modified="2019-11-13" version="1">MKLKRMRQSLNLFWTSDFKQHFSKRQHGSVLPFFNTALNTLIKFTIIMAFKTGVLWDANHKYLSGVAPIFILLGSSLIKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLF3</accession>
    <name>A0A5C6ZLF3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DegT/DnrJ/EryC1/StrS family aminotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03725</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DegT/DnrJ/EryC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00616">
        <property type="entry name" value="AHBA_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000653">
        <property type="entry name" value="DegT/StrS_aminotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30244">
        <property type="entry name" value="PTHR30244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01041">
        <property type="entry name" value="DegT_DnrJ_EryC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="1" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="398" mass="43787" checksum="92302F6574B3DC1B" modified="2019-11-13" version="1">MPGFERFGDLERKEVNDVLDSGVLMRYGFDGMRNGHWKAKELETELQNAFGVKHAQLVSSGTAAVSVALAAAGVGAGDEVIMPTFTFVASFEAILMLGAIPVLVDIDDSLTLDPKAVETAITAKTKAVMVVQMCGSMGDMTALKSICEAHDLLLVEDACQAIGGTYNGKSLGSIGDLGCFSFDFVKTITCGEGGAVITNNDAYYTNTDHFTDHGHDHDGTDRGAETHPFLGYNFRISELNAAVGLAQVRRLPEFLEVQKRNYTVLRNALSLIEGLTFRKVPSGGEESYAFLNFFLPDLETARQTTKEFKSNGIDVCFHYYDNNWHYVRKWQHLTEQKSLYPLSAEVKAGLAQLQHKTFEQSNHFIGRNISCLIKMSWTPEALENRATKMAQIVKSILG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLR7</accession>
    <name>A0A5C6ZLR7_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Nuclease SbcCD subunit D</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">sbcD</name>
        <name evidence="8" type="ORF">ESY86_00040</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'-&gt;5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 6">Heterodimer of SbcC and SbcD.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the SbcD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00840">
        <property type="entry name" value="MPP_Mre11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041796">
        <property type="entry name" value="Mre11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004593">
        <property type="entry name" value="SbcD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00619">
        <property type="entry name" value="sbcd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5 6 8" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="7">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD91026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="399" mass="44580" checksum="B8D48FB6AB2A26F2" modified="2019-11-13" version="1">MKILHTADWHIGKQLHKMDLSEDLELFFDWLLKVISTEQIDLLLVSGDVFDQANPSQSALKQYYGFLKRMIGTHCKIIITGGNHDSAAVLNAPKAILGFLNIDVVGGAPEAISELFFKHTKQETQVVIAAVPFLRDKDIRKAAAGESYSDKIEQIRDGIQRYFASVNTHYNAHFEGLCFIVMGHLYVQGAHVSESMRDIQIGNQASVKGHIFGEAPNYVALGHIHKPYAVSGTKQVHYSGSPIALSFSEKAEVKQVNVITITGKTVAVNILPIPQFRHLVAFEGTLESVKTQLHHYTLKTQLVSLAEIIVNEPNENVQIRQDFDELQSDHDSDALKIIKSKLNFTNKVRGASEAFEPGISVADVTPMEMFEKRLQLDGNLEHTEELKNAFRQILEELNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLR8</accession>
    <name>A0A5C6ZLR8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_01205</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="65" mass="7681" checksum="EB2112CAF313C9FE" modified="2019-11-13" version="1">MARAMFEYTKTVLDKVSFDATLFCKELKKALQRLLPYEVEELKIFIKSLILQNPELNQCLIYLKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLR9</accession>
    <name>A0A5C6ZLR9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">SRPBCC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_06670</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="155" mass="18164" checksum="428E7792F44584D8" modified="2019-11-13" version="1">MKIYTLHKSQKLPISLETAWDFLSDPKNLKTITPEYMGFNIISGADRPMYAGQLIQYIVTPILGIKTKWVTEITHSVKNEYFVDEQRYGPYALWHHKHFIKEIEGGVEMEDIIDYKVPFGFLGQLVHPFLVKPKLEEIFNYRTTKLEEMFGTYGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-02-10" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLY6</accession>
    <name>A0A5C6ZLY6_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA-(apurinic or apyrimidinic site) lyase</fullName>
            <ecNumber evidence="2">4.2.99.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">ESY86_02815</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FPG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.99.18" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140078">
        <property type="term" value="F:class I DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019104">
        <property type="term" value="F:DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015886">
        <property type="entry name" value="DNA_glyclase/AP_lyase_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012319">
        <property type="entry name" value="FPG_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035937">
        <property type="entry name" value="MutM-like_N-ter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_S13-like_H2TH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01149">
        <property type="entry name" value="Fapy_DNA_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06831">
        <property type="entry name" value="H2TH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00898">
        <property type="entry name" value="Fapy_DNA_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01232">
        <property type="entry name" value="H2TH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="SSF46946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81624">
        <property type="entry name" value="SSF81624"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51068">
        <property type="entry name" value="FPG_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FPG_CAT" evidence="10">
        <location>
            <begin position="2"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD90905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="260" mass="30156" checksum="53BD346A8810DB45" modified="2019-11-13" version="1">MPELPEVQGYKVYIDSTSLHKKIMGFECRDARLLKKPKADFEQHLLKQELTETLRIGKYLFLKTTGDKILVIHFGMTGRPNYYKDEEDRPKFGHIVLTFENGFHFAFENKRKFGWWNLIDSIEDYKSEHKLSDDARDLSLEDFKASLSSRKTHIKKVIMDQSVAAGVGNWMADDILYQAKIHPKKKVQDMTVKAIEQVFDAMKNVIEVAIAHDAHYSDFPKHFLIHFRKEGATCFHTGGKIEKIKLGGRSTYFSPELQQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLZ0</accession>
    <name>A0A5C6ZLZ0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">P-II family nitrogen regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_02305</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030234">
        <property type="term" value="F:enzyme regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006808">
        <property type="term" value="P:regulation of nitrogen utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002187">
        <property type="entry name" value="N-reg_PII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30115">
        <property type="entry name" value="PTHR30115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00543">
        <property type="entry name" value="P-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00340">
        <property type="entry name" value="PIIGLNB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00938">
        <property type="entry name" value="P-II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="SSF54913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51343">
        <property type="entry name" value="PII_GLNB_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="O-UMP-tyrosine" evidence="1">
        <location>
            <position position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR602187-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="112" mass="12328" checksum="4F4A0348AEFE0419" modified="2019-11-13" version="1">MKKVEAIIRKSKFSAVKKALHEVGVNFFSYWDVTGLGNEKEGHVYRGVSYSTSDIQRRYLSIVINDDFEAATIKAILDAAATGEVGDGKIVVSDIAEVYRIRTGEKGADTLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM09</accession>
    <name>A0A5C6ZM09_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">SAM-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_01140</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008189">
        <property type="entry name" value="rRNA_ssu_MeTfrase_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46111">
        <property type="entry name" value="PTHR46111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005917">
        <property type="entry name" value="MTase_YraL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TP_methylase" evidence="6">
        <location>
            <begin position="63"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD91338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="238" mass="26846" checksum="EFE70839BEEB05E0" modified="2019-11-13" version="1">MNETYGKLYLIPTRLGDNPPLEVLPLSIKKIIELVDDYIVENEKTARRFIKRISSHKQQSALKLKVLNKYTEPSELNQFLEACKAGKPMGLLSEAGCPGIADPGAEIVNLAHQHHIKVVPLVGPSSIVLALMASGMNGQSFAFNGYIPIDKNERKAALKRLERLSFEQNQTQLFIETPYRNDQIMEDICKNLHDATRVCVACDITLPTEYIVTQTVKEWKNTKVVLHKRPAIFVIHKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMN8</accession>
    <name>A0A5C6ZMN8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DNA ligase</fullName>
            <ecNumber evidence="10">6.5.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Polydeoxyribonucleotide synthase [NAD(+)]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10 12" type="primary">ligA</name>
        <name evidence="12" type="ORF">ESY86_01085</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="10">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the NAD-dependent DNA ligase family. LigA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.2" evidence="10"/>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003911">
        <property type="term" value="F:DNA ligase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00114">
        <property type="entry name" value="LIGANc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01588">
        <property type="entry name" value="DNA_ligase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041663">
        <property type="entry name" value="DisA/LigA_HHH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033136">
        <property type="entry name" value="DNA_ligase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001679">
        <property type="entry name" value="DNAligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013839">
        <property type="entry name" value="DNAligase_adenylation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013840">
        <property type="entry name" value="DNAligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003583">
        <property type="entry name" value="Hlx-hairpin-Hlx_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004150">
        <property type="entry name" value="NAD_DNA_ligase_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004149">
        <property type="entry name" value="Znf_DNAligase_C4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01653">
        <property type="entry name" value="DNA_ligase_aden"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03120">
        <property type="entry name" value="DNA_ligase_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03119">
        <property type="entry name" value="DNA_ligase_ZBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12826">
        <property type="entry name" value="HHH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001604">
        <property type="entry name" value="LigA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00278">
        <property type="entry name" value="HhH1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00532">
        <property type="entry name" value="LIGANc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="SSF52113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00575">
        <property type="entry name" value="dnlj"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01056">
        <property type="entry name" value="DNA_LIGASE_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9 10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 10" id="KW-0235">DNA replication</keyword>
    <keyword evidence="2 10 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="7 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0464">Manganese</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 10" id="KW-0520">NAD</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="BRCT" evidence="11">
        <location>
            <begin position="586"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="active site" description="N6-AMP-lysine intermediate" evidence="10">
        <location>
            <position position="112"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="31"/>
            <end position="35"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="80"/>
            <end position="81"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="284"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="308"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="402"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="405"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="420"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="426"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TXD91212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="665" mass="74234" checksum="EA440A7577685A12" modified="2019-11-13" version="1">MDVKEQLEALRTELRLHNYNYYVLDQPSIADFDFDMKLKQLQDLEAKHPEYDDPNSPSLRVGGEVTKNFETVVHEHRMYSLDNSYSKDDLLDWEKRIEKTIDGKVEFVCELKYDGASISITYENGMLSKAVTRGDGSQGDNVTANIRTIKSVPLQLKGNYPEKFDIRGEIVLPYEGFIKMNEARVEAGEEPYRNPRNTASGSLKLQDSAEVARRPLDCLLYNITGTNLGFDTQFESLKNARAMGFKVPEAATLATSVDEVLKFVDYWDVHRHDLPYETDGVVIKVNDLQQQEELGYTSKSPRWAMAYKFKAEQVSTRLHEISYQVGRTGAITPVANLEPVELAGTTVKRASLHNADQIEKLDIREGDEVYVEKGGEIIPKIIAVDLSKRPVDSKPTVYLEHCPECGTALERQEGDAKHYCPNYNGCRPQIIGRIQHFISRKAMDIEGLGGETVALLVEAGLISHYADLYTLTKAEILPLERMAEKSADNLIAGVEQSKTIPFERVLFAIGIRFVGETVAKKLAKHFKSIAVLANASVEELISVDEIGERIAQSVVDFFASEENRAIIEKLKVHGVSLEISAEKLANQTDKLQGETFVISGVFEQVSRTELKKLIEDNGGKVSGSISSKTNFLVAGNNMGPSKRTKAESLGVPIISEIDFLSKIKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMT1</accession>
    <name>A0A5C6ZMT1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fibronectin type III domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_01305</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="SSF49265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022823623" evidence="1">
        <location>
            <begin position="23"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="2">
        <location>
            <begin position="33"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD91252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="224" mass="24170" checksum="4470FEA8E981924E" modified="2019-11-13" version="1">MKTYFIKTVVLLGVFFISSCESDDSPELLAPTATSETTASNIEATYTTIEINGNVSSTGGSEITSRGVCWSTNQDPTINDSKTTETSNTFTSTIDGLVANTTYNFRVYATNSVGTSYGTVQAFSTSSLDDTMWDFLIVYDPNQSTNADVTFNSDGTTLYDEPSSPGTYASNGTWSLNGNVLTYDIDTDPNNNSSYLFTGTLSNNTMTGTLTHYTGVLNWSATKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMZ9</accession>
    <name>A0A5C6ZMZ9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_00085</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="288"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="333"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="374"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="23"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="317"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD91035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="411" mass="45334" checksum="87608C593DD33F31" modified="2019-11-13" version="1">MFSLFKENIRIAFDSIRSQLLRTILTILIIAIGITALVGILSAVSALENTISSDFSSMGANTFNVQRYDFNNQRANDKEKINPVISYREVKTFEEDYQFPFTQTSISFQGTSTAEVKYENEKTDPEVQVFGVNENYITNAGLEVELGRSFNYFDIQNSNTVCVIGSDLRKALLQDVNPLNKTISIRGSKFKVIGVLKAKGATFGNNQDLRVLMPLQKARTIYTNANINYNLSVKTDNKNMLEGAQDEAILLFRNIRGLNPIENNNFALQRSDDLINRISTITSGLSTVAWIVSIITIFGSTIALLNMMLVSVSERTREIGVRKALGAKRATIAFQFFIETIIIGQLGGLLGICLGILVGWGVSAAAGFEFTTPWLAMTSAVIITFVVAVISGLMPAIKAAKLDPVESLRYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN71</accession>
    <name>A0A5C6ZN71_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Bifunctional (P)ppGpp synthetase/guanosine-3',5'-bis(Diphosphate) 3'-pyrophosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_03445</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the relA/spoT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015969">
        <property type="term" value="P:guanosine tetraphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05399">
        <property type="entry name" value="NT_Rel-Spo_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01668">
        <property type="entry name" value="TGS_RSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004811">
        <property type="entry name" value="RelA/Spo_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007685">
        <property type="entry name" value="RelA_SpoT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033655">
        <property type="entry name" value="TGS_RelA/SpoT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13291">
        <property type="entry name" value="ACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04607">
        <property type="entry name" value="RelA_SpoT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02824">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00954">
        <property type="entry name" value="RelA_SpoT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="SSF81271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00691">
        <property type="entry name" value="spoT_relA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TGS" evidence="2">
        <location>
            <begin position="402"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="734" mass="83681" checksum="7E9BC5F9A6F8FF68" modified="2019-11-13" version="1">MTEVDIDKENAKIAKAYKQLLKVSYQTLTADDKKLIRHAFEVALDAHKDQRRKSGEAYIFHPIAVARIVAGEIGLDATCIAAALLHDVVEDNPNFTIDDIERLFGETVARIVDGLTKISSLSKDTDVSTQAENFRKMLLTLNDDVRVIIIKIADRLHNMQTMDSMRRDKQEKIASETLYIYAPLAHRIGLYNIKTELEDLGLKYTEPEVYEDILEKIQESKEEQDLYIKAFSKVIEDSLEQEGLNYEIKGRPKSIFSIRRKIVKQGVDFDEVYDKFAVRIIYKSDVANEKFLAWKIYSIVTDNFTPNPTRLRDWISSPKSTGYEALHITVMGPKGRWVEVQIRSERMNEIAEKGYAAHYKYKEGDAEDALDTWIDKLQEALESNETNAVDFVEQFKLNLYSKEIYVFSPKGELKSLPKGATSLDFAFSIHTEIGMKTRGAKVNGKLAPLSHVLQSGDQVEILTSEHIKPNRNWLDYATTARARSKIKSSLKDEKKDLAEDGKEILRRKLKQLKVPLDEKSVNEMVNFFKLKTSLDLFYRVGIGSIDNKMLKEYVASRSNVFMSYIKNKIRKPTVPPDIDKDEITANYDQLVFGPDEQKLDYKLSECCNPIPGDPVFGFLTINEGIKIHKKNCPNALSLQSNYAYRIMQAKWIDSSQQEFATKIELSGIDKLGLVNTITKVISSNMHVNMKSISFETDGGIFRGKINVVVNNNSMLQKLMDNLKKINGIDKVTRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNJ6</accession>
    <name>A0A5C6ZNJ6_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">GMP synthase [glutamine-hydrolyzing]</fullName>
            <ecNumber evidence="9">6.3.5.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">GMP synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Glutamine amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 12" type="primary">guaA</name>
        <name evidence="12" type="ORF">ESY86_04185</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Catalyzes the synthesis of GMP from XMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + H2O + L-glutamine + XMP = AMP + diphosphate + GMP + 2 H(+) + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:11680"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.5.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Purine metabolism; GMP biosynthesis; GMP from XMP (L-Gln route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.2" evidence="9"/>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00189">
        <property type="reaction ID" value="UER00296"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003922">
        <property type="term" value="F:GMP synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016462">
        <property type="term" value="F:pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01742">
        <property type="entry name" value="GATase1_GMP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01997">
        <property type="entry name" value="GMP_synthase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00344">
        <property type="entry name" value="GMP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001674">
        <property type="entry name" value="GMP_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004739">
        <property type="entry name" value="GMP_synth_GATase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022955">
        <property type="entry name" value="GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025777">
        <property type="entry name" value="GMPS_ATP_PPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022310">
        <property type="entry name" value="NAD/GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00958">
        <property type="entry name" value="GMP_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02540">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00884">
        <property type="entry name" value="guaA_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00888">
        <property type="entry name" value="guaA_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51553">
        <property type="entry name" value="GMPS_ATP_PPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="5 9 10" id="KW-0332">GMP biosynthesis</keyword>
    <keyword evidence="3 9 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 9 10" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GMPS ATP-PPase" evidence="11">
        <location>
            <begin position="195"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="168"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="170"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="222"/>
            <end position="228"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TXD90573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="511" mass="56625" checksum="F17B04FF19640966" modified="2019-11-13" version="1">MQHNKVLILDFGSQYTQLIARRVRELNIYCEIHPFNKIPVDSESYKAVILSGSPNSVRGESVLHPDLSQIRGKKPLLAVCYGAQYLAHFSGGLVEESNSREYGRAHLSYIKQDEDFFTGITKGSQVWMSHSDTIKQLPTNAVLIASTHDVENAAFKIAGETTYGIQYHPEVYHSTDGGQLLQNFLVHIAKVEQDWTPQSFVEESVDTLKETLGNDKVVLGLSGGVDSSVAAMLLHKAIGKNLYCIFVNNGLLRKDEYTSVLQQYEGMGLNVKGVDASARFLDALASISDPELKRKAIGRTFIEVFDDEAHAIKDVKWLAQGTIYPDVIESVSATGGPSATIKSHHNVGGLPDFMKLKVVEPLKALFKDEVRRVGKSMGMDPNILGRHPFPGPGLAIRILGDITPEKVRILQDVDAIFIENLKSWNLYDKVWQAGAILLPVHSVGVMGDERTYEKCVALRAVESTDGMTADWVNLPYEFLQKTSNQIINKVKGVNRVVYDISSKPPATIEWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNJ9</accession>
    <name>A0A5C6ZNJ9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="63" mass="7256" checksum="E76246C3054E07DE" modified="2019-11-13" version="1">MKPTTKIILKAALINGLFWSALLMLITYLKNGILYSDYLPLWFLFFAGTGAARKYYFLTKSDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNQ7</accession>
    <name>A0A5C6ZNQ7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">N-acetylmuramoyl-L-alanine amidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_00375</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008745">
        <property type="term" value="F:N-acetylmuramoyl-L-alanine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02696">
        <property type="entry name" value="MurNAc-LAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002508">
        <property type="entry name" value="MurNAc-LAA_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01520">
        <property type="entry name" value="Amidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00646">
        <property type="entry name" value="Ami_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022854712" evidence="1">
        <location>
            <begin position="24"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="MurNAc-LAA" evidence="2">
        <location>
            <begin position="94"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD91087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="373" mass="41563" checksum="2D415741A1BD57DF" modified="2019-11-13" version="1">MTTKSIYLLVLILSLFFSFPTAANAFQKNKDTFVVVLDAGHGGHDSGNLGGGYMEKEIALNIVLAVGKSLEAIKDIKVIYTRKTDEFVTLRGRAKIANDADADLFVSVHCNAHNSDAHGTETFVLGLHANQRNFEIAKKENEVIFLEADYEQHYEGFDPNSPESLIGLTLIQEEYLDQSIALARAVEDNFQNQRKLKSRGVKQAGFWVLHNTYMPSVLIETGFLTYKKEGAFLNSSKGQIQMASSITDAVLNYKKHLDLNVGDGIYKQETEGITEVLDAESEIYNGIVFKVQIAASSKELEPKPFNFKGLETISREKVGKLYKYFYGETSDYAEIRRLELVAKSKGYNSAFVKAFKDNKSVNLSTVLKTASSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZP17</accession>
    <name>A0A5C6ZP17_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD family phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_03535</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="223" mass="24859" checksum="5B14FE123DF23764" modified="2019-11-13" version="1">MFKAVLFDMDGVIVDTEPLHRKAYYQMFDAVNIEVSEALYASYTGQSTFNICESVIAHFKLHLGPRTLVDMKRDNFKTLFENDSSLQLLEGALELIKDYHRHGMTLVLASSASMNNINRIFERFDLNPYFVGKVSGADLKASKPDPEIFVKAAELSGHSKNECMVIEDSTNGINAAKAAEIFCIGYDALHSKDQDYSNADLVISNFDEISVKNLANLSLSRAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZP41</accession>
    <name>A0A5C6ZP41_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_00340</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="87" mass="10056" checksum="5E839A1E26FD7D82" modified="2019-11-13" version="1">MKKKNIIKDTLVNGKIKNGMFLLDNKKSKIYGIPYLLGGYDIKKQRIGVTNKNNLITNISVAKQSLLLFVIGRNYNLNLSYEYERME</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZP48</accession>
    <name>A0A5C6ZP48_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA small subunit methyltransferase E</fullName>
            <ecNumber evidence="6">2.1.1.193</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_00395</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>S-adenosyl-L-methionine + uridine(1498) in 16S rRNA = H(+) + N(3)-methyluridine(1498) in 16S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42920"/>
            <dbReference type="Rhea" id="RHEA-COMP:10283"/>
            <dbReference type="Rhea" id="RHEA-COMP:10284"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74502"/>
            <dbReference type="EC" id="2.1.1.193"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the RNA methyltransferase RsmE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.193" evidence="6"/>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006700">
        <property type="entry name" value="rRNA_ssu_MeTrfase-E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30027">
        <property type="entry name" value="PTHR30027"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04452">
        <property type="entry name" value="Methyltrans_RNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015601">
        <property type="entry name" value="MTase_slr0722"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00046">
        <property type="entry name" value="TIGR00046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR015601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD91091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="235" mass="26907" checksum="BF4C8B9CFD84B860" modified="2019-11-13" version="1">MQLFYNPNVSEKDHTIQFSKEESRHMVKVLRKNLGDQLHITNGIGWLFTAEITQADSKNCMAKITHSEFQESHDYKLHLAVAPTKMNDRFEWFLEKATEIGIDSITPIFCENSERRVVKAERFEKILQSAMKQSLSCYLPKLNVAISFHEFINQDFEGELFIAHCEDTQKRSLKNTVQPKTRITMLIGPEGDFSTSEIDLAKAKHFKPVTLGNTRLRTETAAIVACHSVAFVNEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPA1</accession>
    <name>A0A5C6ZPA1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_00810</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1080.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028974">
        <property type="entry name" value="TSP_type-3_rpt"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="308" mass="33979" checksum="EB2F37D97839E401" modified="2019-11-13" version="1">MPKVYVLFLLCLVLASCDDGDIIEAELDFDQELKRCGDDESETYVLYDTKLDPNESLTLKFPVAGNRVIFNPTSYGAIKEIEINGVNTSFSYRIYDGDPNNLICQVVPEPGTTIINDYKAAAGAKASFISTFVDDDMDGIPSELEGRGAQAADGSYPDAIDTDGDGLPDYQDADDDNDNVLTINEGVQITEDGQFGEVLDTDGDGTPNYLDNNDDGDLVLTKDEDENGNLTLSDDFDPESEMINVPRFLDDSATESFPQDNLRFTQYRRSVTVRVVILTPNIEILQLSTLIMGDYELNPPLMLPLEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZRG9</accession>
    <name>A0A5C6ZRG9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Preprotein translocase subunit YajC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">yajC</name>
        <name evidence="9" type="ORF">ESY86_00965</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the YajC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003849">
        <property type="entry name" value="Preprotein_translocase_YajC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33909">
        <property type="entry name" value="PTHR33909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02699">
        <property type="entry name" value="YajC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01853">
        <property type="entry name" value="YAJCTRNLCASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01323">
        <property type="entry name" value="YajC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00739">
        <property type="entry name" value="yajC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD91190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="95" mass="10438" checksum="9B4D760220DB4FBF" modified="2019-11-13" version="1">MGIGDILPFVGMFAVVYFFMIAPQMKRAKNEKKFAAALKRGDKVITKSGVHGKVVDLNEKDSSCVIETLAGKIKFERSAISMEMSQKLNTPATVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZA17</accession>
    <name>A0A5C6ZA17_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Tyrosinase_Cu-bd domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19585</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000043">
        <property type="protein sequence ID" value="TXD86693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003115">
        <property type="entry name" value="ParB/Sulfiredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036086">
        <property type="entry name" value="ParB/Sulfiredoxin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002227">
        <property type="entry name" value="Tyrosinase_Cu-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02195">
        <property type="entry name" value="ParBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110849">
        <property type="entry name" value="SSF110849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00498">
        <property type="entry name" value="TYROSINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosinase_Cu-bd" evidence="1">
        <location>
            <begin position="59"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS00498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="451" mass="51883" checksum="5CD43F0ADE16121E" modified="2019-11-13" version="1">MGYTRKLIDLSLLNINIENPRFEMVGNQREAIKTMIDDQGDKLTKLATDIVEEGLNPGDPIFVVKHEKKDDQFNILEGNRRVTALKLLENPDLIPETKKALLTKFRKLSEDYNKSPIDKINCVLFDSEEDAEHWIELKHTGQNDGIGTVSWDAQQKARFDERVKGTSSYALQVIDFLHKESTVEKDIKSKLKDVKSSSLQRLVTDPDFRRVAGIEIKDGKVRTKYEPSEVAKPLTKAVRDLLRKDFTVKDIYYKDDRLNYLETFKKTDLPDKTQELAGNWELISTTRPKKIDPKKAKKANKKSITLISKRKTIIPKSTIIPISQPRVNKIYHELKDLDLTDFENSGAITFRVFIELTLDTYLETFPLASVNESSKLSHKLSSVAKDLETKKILSKDKLKGAYTASTMKDSIFSINTFNAYVHNKDFHPEPESLKKNWDNLEIFFVKVWELI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZA63</accession>
    <name>A0A5C6ZA63_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PorT family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_20225</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000061">
        <property type="protein sequence ID" value="TXD86424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025665">
        <property type="entry name" value="OMP_b-brl_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13568">
        <property type="entry name" value="OMP_b-brl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023026893" evidence="1">
        <location>
            <begin position="20"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="OMP_b-brl_2" evidence="2">
        <location>
            <begin position="22"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="201" mass="22975" checksum="A0E18A5188C1BE4F" modified="2019-11-13" version="1">MKRLLFYTISFLCFYTSNAQKNFGVFAGINHINLTDANNFPTQGSSNGIGLNFGLSYDIEISEKVIFSPRIVYSQQGTTKSRAEDVNDVDDFVTAVYFQYKLNYLNFPMQFKIFRQPYILAGPYAGFVLYEERYNLDFGDIESKIDYGINLGIGYNFKNLFTELNVQQGFASLVVVENTPNSDEFKLNNTIIQLSVGYKFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAD9</accession>
    <name>A0A5C6ZAD9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mercuric transport protein MerT</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Mercury ion transport protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="primary">merTP</name>
        <name evidence="17" type="ORF">ESY86_19885</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the MerT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000051">
        <property type="protein sequence ID" value="TXD86569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015097">
        <property type="term" value="F:mercury ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017969">
        <property type="entry name" value="Heavy-metal-associated_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003457">
        <property type="entry name" value="Transprt_MerT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02411">
        <property type="entry name" value="MerT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="SSF55008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01047">
        <property type="entry name" value="HMA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="13 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0475">Mercuric resistance</keyword>
    <keyword evidence="11" id="KW-0476">Mercury</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="49"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="91"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="16">
        <location>
            <begin position="131"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00030934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="TXD86569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="201" mass="22190" checksum="0A2350BACBECFE66" modified="2019-11-13" version="1">MSTEETSKKAAYTGLFAAVAASSCCIPPVIALIAGVGGSTSALSWMEPFRPYLIVLAIVAIGYAWYDYLKQKKVEDCCEIDAKPKWFQTKGFLIGITLFAVISISFPYYSHIFYPDNKKEIVIVNQSNIQTVNFDVQGMTCASCEQHVTHAVKKLEGIVNVAASFEKANTKVEFDDSKTSKEDIEKAINSTGYKVIDKEEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAN9</accession>
    <name>A0A5C6ZAN9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19425</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000040">
        <property type="protein sequence ID" value="TXD86744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1137" mass="129738" checksum="2B9578673F9DFB40" modified="2019-11-13" version="1">MASKVYRLFQDRDLQDWEDRGEPYGPTVIEDINNPDGDYSITDPTSIPSPFARVDLVRSAFKYVADSNNFDGNTIYHKLVSDCFDVAEMFFNFDTLGDRVQIKTWDKSTDLNNLLTSTNPKHKLLGETLDLFLKQDASSNNFDALNKLYFIFYDNKIVGGTSPTTLFFTSANDLSFANIENGNDTFFDSDLKPLYKRDIEFQKYIYKLVNGYPELKIKMRDLADYLEKSLSRLDSYNIGLYGQLSEIQEENANDLVGKLNSSYSSLDIGENNNIEILGVPLKKKKIENRGTTIADLSEFVIKSSKTDTKPLILQNNFTEPLIYTDRNVKWDNNWTIPYFDEKPINERTLPNQLDKYPYLTVSDFLQAQIIRVPYVLNSDKYFDGNIKNESGDNNKSFLLPLSKKFFEYFDTEDLQKPMPNGKPMFEAKVFSGSIEVKLRIPIKGNRNVDYITFERYYGSAKSDNKDITNNKGLIIDNKISLAVYPFLKIENDSFYKIMALDQGVDSINSHSSFLLNFYSNKTKDSLEVDKTSRTLKKDGIIQTDFYSLEHQFDYIEAGYNDNLGIIIPKLKTNTGSKKMKFAVDFGTTNTHIEYKVEGDKSSLPFRISKDEIQYETLHNSNTTDTDIVEIESFIRHEFLPKIVSDNSEFNFPIRTVSGESRSLNFSSTPEAFADINIPFDYEKYASNIDTEITTNLKWSDFEDSNSPNKIRVEKFIEKILLLIRSKVLFNNGDINKTELIWFYPSSMDLDKIDQLEGIWNKYFTKYFKEGKTSKLSESIAPYYYYQNHGNVIAGTDTVVSIDIGGGTSDVVIFQKEKPIALTSARFAANSIFGDGYGGSPNNNGFIVKYQKKISDLLADNKLKHLERTFNQIFSKKKSEDLVAFFFSLEKNKTVISEKAPLQFNSWLSTDNDLKIVFIVFYSSIIYHIANLMKAKGLDAPTNILFSGTGSKSILITNGSNNLDKLDKLTGIIFDKVFEGNKTHKVKINIEPNPKEITCKGGLEIDVDSIGDIEDIKSVLLGDTEKSTINENPIKYNNIDDDVINSVVSEVDNFIDILFSIDDTMNFKKYFGVNSAHFDNYKTILKEETLNLLDTGLRRKIESLNGNTNIPLEESLFFYPLVGALNKLSYKIVTELNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAP0</accession>
    <name>A0A5C6ZAP0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Outer membrane beta-barrel protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20335</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000066">
        <property type="protein sequence ID" value="TXD86380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022662885" evidence="1">
        <location>
            <begin position="19"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="177" mass="19452" checksum="6C0677C35ACA2612" modified="2019-11-13" version="1">MKTLFFFLVLATSLSLNAQITKGNWLVGGDASFNSSTVNDSDGNEVGKSSGIRIFPNIGHFFFDKFAVGLTPSFFYSKTKNGPSSVGYGIGPFARYYFLKPENRINLFADANFIYFSSKTKGFSSTSNSSYRIKAGPVLYFNSSVALEFTIGYNSANFSTTTNTVELGFGFQIHLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAU6</accession>
    <name>A0A5C6ZAU6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19685</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000045">
        <property type="protein sequence ID" value="TXD86645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="322" mass="37377" checksum="99ABC01826A23B13" modified="2019-11-13" version="1">MKYLTIFILTILFYSCESKAQSFVLADKIETTELDKKINIKGTRILIDKPENYTYIDELKRFQKNSDNYFQFVEIPNQDYNQTAPNVINKIAQLESQGGEIRVKKEFKLGDYNAFFALAPQGNVSEQVILAFGDNSFSVLVMGIFPNDEKERKEITDLILSSYFDKDLKPNLDDNLFHKVNLDNSDFKLSTVNGTLGTYTLNGQQIKDENLFINSFLIATLPYTNDFDLKKYSDNLIKKYENNTFEEKRIEIDIISEKEYKEEKNKIIKVDMIGTIQGKKSKMFQYIKQTPNGIIQFVGFDFTEDSSYLNEYKTIAEKITLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAZ5</accession>
    <name>A0A5C6ZAZ5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SAM-dependent DNA methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_17750</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000028">
        <property type="protein sequence ID" value="TXD87160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022749">
        <property type="entry name" value="D12N6_MeTrfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003356">
        <property type="entry name" value="DNA_methylase_A-5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12161">
        <property type="entry name" value="HsdM_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02384">
        <property type="entry name" value="N6_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HsdM_N" evidence="2">
        <location>
            <begin position="9"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="N6_Mtase" evidence="1">
        <location>
            <begin position="154"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="649" mass="74774" checksum="E48B3221724D79D1" modified="2019-11-13" version="1">MIDFKEKANLIWEVADLLRGDYKQSDYGKVILPLTVLRRLDCVLQPTKDEVLAHLPKVEDKPDKTKDLILNKIAGHNFHNRSQYDFKKLVAEPDKVAANLRNYINGFSSSSREIIEYFNFDDQIERMDDPKADILFQIVKKFSEIDLSVMDSMDMGYTFEELIRRFAEQSNETAGEHFTPREVIKLMVNLLFISDNETLTKEGIVKTLYDPACGTGGMLSIGEQHLKSFNKKAKLEVFGQEINPESYAICKSDMLIKGQNPSNIKFGNTFTVDGLEDEKFDYMLSNPPFGVDWKKAQKTIKLEHENKGYSGRFGAGLPRINDGSFLFLQHMISKMKPDGTRIAVVFNGSPLFSGSAGSGESNIRQWIIENDWLEAIIAMPDQLFYNTGISTYVWIVNNKKEKQRKGKIQLINATGTKDDELIAEGKIDFNRFYEKMTKSLGNKRKKIIENGEEKGIGFITELYGDFEENGFSKIYPNDFFGYWRATIEQPDWSDLMIKVAHDKQALVEFLNNASSEDIERKVNDFETLSKMHIDEGKWILKENELTIEKGKKIKVKPNSSSRDYENIPFLKLDANKKLVSQTIKDYFKREVKPHLPEAWVDESKTKIGYEINFTKYFYEFKPLRSLEDIKAEIFALETTALELEKKVLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZB01</accession>
    <name>A0A5C6ZB01_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4386 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20325</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000065">
        <property type="protein sequence ID" value="TXD86387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025495">
        <property type="entry name" value="DUF4386"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14329">
        <property type="entry name" value="DUF4386"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="201"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="227" mass="25180" checksum="BF4A9D351CF12588" modified="2019-11-13" version="1">MTINEKHRELVATARTAGVLYLAMAVSGILGFLIFHPQVFDSEDSQKTLTKLIDLESLARTRLLFEFAIVVSQAITAVWFYKLFRHINEWAAWTVGIWGMINSIAIMISAISMGSAIEIASSSQNVEDKLILIELLSSLITNSWGVGGLFFGLWLIPLGYIITSSKKMPVWLGRTLIIGGIGYLLSTVANYVGIKSPVIDYLTIPATIGEFWMIGYLLIYGIRQVNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZB41</accession>
    <name>A0A5C6ZB41_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transketolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18685</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000033">
        <property type="protein sequence ID" value="TXD86955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transket_pyr" evidence="1">
        <location>
            <begin position="10"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="317" mass="34092" checksum="CE654CB375D82581" modified="2019-11-13" version="1">MKTYTNTGNKDTRSGFGAGLTELGKTHENVVALCADLIGSLKMDDFKANHPERFFQVGIAEANMIGLAAGMTIGGKIPFTGTFANFSTGRVYDQIRQSVAYSNKNVKICASHAGLTLGEDGATHQILEDIGLMKMLPGMTVINTCDYNQTKAATIAIADYEGPVYLRFGRPKVANFTAEDQKFEIGKAVQLTEGSDVTIIATGHLVWEALEAAKTLNEKGISAEVINIHTIKPLDDKAILKSVAKTKCVVTAEEHNYLGGLGESVARVLSTNQPAPQEFVATQDTFGESGTPELLMEKYGLNAEAIVKASEKVLKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBE0</accession>
    <name>A0A5C6ZBE0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000040">
        <property type="protein sequence ID" value="TXD86742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="140" mass="16425" checksum="CCF23920DCFB290D" modified="2019-11-13" version="1">MDLNEFYSIIFEWGGLTYRGVFSDDLFTEGLYASIGLITTIISLFLVIAFYFIINRPSFSRWQHWLIMLLINFVIAFLIGLIVPQNIFYGLGIDYDIMEYITFGLITAITTTAFFILWTYCFKWWKSHAKGTPKLFFGKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBQ4</accession>
    <name>A0A5C6ZBQ4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_20400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000070">
        <property type="protein sequence ID" value="TXD86314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="255" mass="30310" checksum="73657A2E0D0B7426" modified="2019-11-13" version="1">MNRLLILLFSISLIGCCNEPKLLNNGLTQKTTQITEYTIEVKNDSLNNKIQDTLVITEKKYNENDQIISRHQRNLFADETMDIEFIYNNDKNVKREIVTLSNDSSNFIVDYLYKDTLLIETKSESKNDIFQFKQIGGYKYNSDNELKESSIKQIYIDVETNDTITNTLEISKYNNKEFVTESKLSDFTKPERNRNTEYKYDCGILMEMKEFNSKDSLTSKTEYKYVFDKFENWIKRESIENDNLNYIRTRKIEYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBU6</accession>
    <name>A0A5C6ZBU6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Gamma-glutamylcyclotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_17615</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000027">
        <property type="protein sequence ID" value="TXD87252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06661">
        <property type="entry name" value="GGCT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013024">
        <property type="entry name" value="GGCT-like"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="220" mass="25145" checksum="08AE9EFF71A286B4" modified="2019-11-13" version="1">MKTTLAISIIVLTALLFGCSENQTTRTITIEDGKIGMIEYGSLMSKNSMEKRLKRSYEDSVYRVHLQGYKRDWNWHTSMNSPSGAWFYLRGTDTVPVNYIRALNITASENDKINALLFLITPEELAEIDRREFGYTKVDVTDKIAGLEIEGGPVYAYQAKQEYTYDGKKETNSVLSQCYIDRVAIACDSIGKEFRDEFEASTKPYNKETVASHLIWKDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC18</accession>
    <name>A0A5C6ZC18_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Porin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_16235</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027385">
        <property type="entry name" value="OMP_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13505">
        <property type="entry name" value="OMP_b-brl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023071815" evidence="1">
        <location>
            <begin position="27"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="OMP_b-brl" evidence="2">
        <location>
            <begin position="18"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="213" mass="24112" checksum="6B1F501509D5F7B0" modified="2019-11-13" version="1">MINKHMITLRNIIFFSIILFLQSLSAQDNKNVEEGDWMLSSRIGFGTLEVEDVAKTNATVAEVFLGREFLLSNQFSLYTGLEFSNVNSNFANGSNQNLFLSNDYLSLPINLRISYDDAEKLSLYADFGIYGSYLLKSTVEIEADDLDDSENGLGFNFGYQVAFGAKYKFQDSRYSINFGLRTKNDLINSYKSSEQEFQINDVYLIEIGLGFAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC43</accession>
    <name>A0A5C6ZC43_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000055">
        <property type="protein sequence ID" value="TXD86506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="219" mass="25953" checksum="00BC4B6F2D4152C1" modified="2019-11-13" version="1">MNIKYKPRNLNSNELRILRYLKTKTEKNERGKIKFYHFLIAGLLGVCLIYITSIIPDSFWTLILGTLAVFSFAFIVFTPYEIYKAKKQHKEFLNLLNSLIEKGTVETCQIESTKIAIAPEYEDENDMYIIKLNENEVLYIWDTEYKLNRNFPSLKFEIYGIDFFKITGKQINPLSEKILPLKIDRKAKWNFMKQYGIYGHLEIEKSNFEKLILKYKNCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC61</accession>
    <name>A0A5C6ZC61_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Universal stress protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_20120</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal stress protein A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000057">
        <property type="protein sequence ID" value="TXD86485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="2">
        <location>
            <begin position="2"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="265" mass="29659" checksum="16305F07E4739DF9" modified="2019-11-13" version="1">MKSILVPVGSSKNAVSHLQYAVDFAKSFGAKLYVVQIYNVYTKAGTMIKIDHILERESLEFLTKHVAKVDTKGVEISIRTFKGKLVDTLELACNALEVDLILLEPRTNSLKEEVYLGKTSGKIVKQTNIPALIVPEGFKFKSIDTILMAIKSAIIKNEAALNPLKDIKAQFKSTVNLLLVKTPFHNEGDFNVTEDLKSLISNTAYSENPTTIQAVMEHYKENKPDLLCVVRRKRGFFSKMWESNTILKKDFHSSTLPVLVLSGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC86</accession>
    <name>A0A5C6ZC86_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18325</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000031">
        <property type="protein sequence ID" value="TXD87016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="78" mass="9092" checksum="278BAF7E2E07F544" modified="2019-11-13" version="1">MKYLILFCFIASATSIICGLALEVSFAEKLVGFGTVGLFIITFPLFAYYRWKDRSLKDYMLNKENLDKMRDSQKESKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCJ5</accession>
    <name>A0A5C6ZCJ5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_19430</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000040">
        <property type="protein sequence ID" value="TXD86745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022885546" evidence="3">
        <location>
            <begin position="21"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="191"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="216"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD86745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="405" mass="46728" checksum="AB12F957DB7045D4" modified="2019-11-13" version="1">MYKLFSLFLVLLFTSLTLNAQNSKEEYEKAVDYCACKIAYAYTEDFASKNPRLDEKKSFDEVISIQLNDCDKKNVSSSELEKLLKENKFNGFSKTLIPDVKKAKNSYSDNFNKEEAINSILNSFELSFDKIEIKSELSNGLNNKLQSFEKQEDIVEEIKSETTTNPNLLNEINHSDRVINEGSVETSENSFFPNWLLFAIILLASILLFLNNHLKIKKLKESAKRHRDEIEVLKNEKSIFNQSNNKSQNNSRFERDIYQKIEDVNDAIRKLQSKNTSKNLHPITSQKNQVKNIPQTNQKEIQKFVYAKTPISDKVFNALDVTENKDGKFYKFLIKDNNVAEFQFFNTENSAIRAVNAPDSFLYPACEETEPLNQNAKKIITNKPGVAIKQGEKWIVKEKAQITYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCR1</accession>
    <name>A0A5C6ZCR1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF4097 family beta strand repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_17195</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000025">
        <property type="protein sequence ID" value="TXD87404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="364" mass="41523" checksum="6A53FFE5AEDBB760" modified="2019-11-13" version="1">MKTIISYQFILVLFLAPMFLFANHERDWNGKHSEEKIIKKEFSVLANATLKVDNSYGNINVTTYEGTLIAIEVHIKTNGNDEDKVRQKLRDIDVEFTASSAYVSAKTLFSKSKSNSWWNWGRDNNVNMEINYIIKLPISNNVDLNNDYGSISLDRLEGRANLNCDYGKITTKELMADNNNISFDYSNSCYFEYIKSGKINADYSSYTVAKTKNLAITADYTKSEVEIAENVDYNCDYGSVNINNANNVNGNGDYLTVRLGNIYKNVSLRADYGSIKIDNMTANAGNIDIESDYNGITIGYDEAYDFSFDIDLEYASLRNAEEFQFTKKRVESTDKYYQGYYRNANSSNRIRIKSDYGSVTFKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD10</accession>
    <name>A0A5C6ZD10_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF2892 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_17040</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000025">
        <property type="protein sequence ID" value="TXD87377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="33"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="164"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="185" mass="21273" checksum="27FAA48D39BB4B6B" modified="2019-11-13" version="1">MFNKNIKLVIAGLIIAYAIYEFTESNIGNGIMYILLSTIFIFLYFKNELILLAFLKLRKQDFEGAKRWLDKIKSPSGALVKKQEGYFYFLHGVMVSQTNMNDAEKHFKKALDLGLSMDHDKAMAKLNLAGIAFSKRRAIEAKKLLKDAEKLDKRGMLTEQIKMMKDGMKKSQGPKQHYGNRNARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD28</accession>
    <name>A0A5C6ZD28_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19750</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000047">
        <property type="protein sequence ID" value="TXD86605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="309" mass="35198" checksum="4316CB96DA63E412" modified="2019-11-13" version="1">MKILKKSLIVIASLILVSSVAGYLYFDKKFTPKSNNLNVSGESSTIPIYWKESSSTKISALLLKIKIKGIEDGFYMQFDTGSPNTIFYKSSLDSIQKLYGIADFNEDSTKTKLSFSLGKMDIKSDDFLVYNVQKNWSHKDSIKIVGTLGTDVMEFRTTKFDFKNSKISFDNTKLKESNSDFKFQKRRILIPVTVSNKKVNVIYDSGTSGFEYITSKDIWEKMKTENKDINLTESNSMGRVLKTYTIGSNSAINFQNEFVNLKEVTYIEGYSSFQYLMMKFTGMGGMLGNKLLIDKIVTFDCKNEKYSIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD35</accession>
    <name>A0A5C6ZD35_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">T9SS type A sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_18470</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000031">
        <property type="protein sequence ID" value="TXD87042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045474">
        <property type="entry name" value="GEVED"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20009">
        <property type="entry name" value="GEVED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022966523" evidence="1">
        <location>
            <begin position="23"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="domain" description="GEVED" evidence="3">
        <location>
            <begin position="838"/>
            <end position="914"/>
        </location>
    </feature>
    <feature type="domain" description="Por_Secre_tail" evidence="2">
        <location>
            <begin position="931"/>
            <end position="1006"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF20009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD87042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1007" mass="109049" checksum="3AB248D7AFBD5838" modified="2019-11-13" version="1">MRAKLQLIHLLLILLVTPSLLAQDNTWEATRFINGTQGVTLEHLDEANFSVLQLNVAKLKQQLQNAPLRSTSNGQSNVVIELPSVDGQLQQYRVVETAIFSSEAGANNHPEIKTYLGSRTDRSEARVRFSVTPMGLKAMISEPGRDLFFIQPVTKFSNGQYLVYNREARVGHIESFECSTEAVDVDLNMLQNTNNRDANDQLLRTYRIAISTTSEFTGFWDDGNASNGGPQEDALAQVVATLNRVNEVFETDMAINYVLVDTEDDPALDLIYSGTDPYGFNLSSQLQTNLTATVGEADYDIGHLFDYDDNNGFSGCIGCVCQAGKGSGFSAHLFTDNNGGPFFPDFFDVDYVPHEMGHQMGANHTFSFRSEGAGVNAEPGSGTTIMGYAGITGPNNVQNHSDAYFHYFSIVQILDNVTTAPNDCAITTAITNNAPVANAGSNYSIPQGTAFILKANATDADGTDILTYCWEQIDNGITTQNNFGPTKTTGALWRSRPPSTSPNRYMPVLERVLAGELTQINPSITANNTSWETVSTVARELDFALTVRDRSEAGGVGQFPQNSFDEMSVNVEEVPAFTVNTPPNWAAGSTQTASWVVGQTSLAPINCQNVNILFSSDGGATFIPLAQNTPNDGSQSITVPNVAEIDNARLWVEAADNIFYAVSPEFEISSAPDFNINITSFDTHECSVDDLIFNLDFATSNGFSENATFSVTGNPSGTNVTFSAPSLSSDGSFTMAISGLASVASNTYNLLVSATAGSISKSVALPIIIDNDPCASVANNSFDTSVTRVLFNTIDNVSAKPSGYSDYTAQVTDVNRESAYELTVQVNTDGDFETGTLAWIDWNQNCSFDDNESYNLGVAEDVEDGLPSNAPLSITVPADAVLGMTILRVSTRYASYPGPCSNGFDGEVEDYSLNVLTTLAVEDNVFENFSLFPNPNQGEFTIKLNSTSNQDIQVDVFDLRGRKVFNERFGNNSNFNQTLSLGNVQTGMYLVTISDGNRKTTKKIIIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDE6</accession>
    <name>A0A5C6ZDE6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">N-acetylmuramoyl-L-alanine amidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_17895</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000028">
        <property type="protein sequence ID" value="TXD87187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008745">
        <property type="term" value="F:N-acetylmuramoyl-L-alanine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02696">
        <property type="entry name" value="MurNAc-LAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002508">
        <property type="entry name" value="MurNAc-LAA_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01520">
        <property type="entry name" value="Amidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00646">
        <property type="entry name" value="Ami_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022844347" evidence="1">
        <location>
            <begin position="23"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="MurNAc-LAA" evidence="2">
        <location>
            <begin position="92"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="213" mass="23828" checksum="FFF4335714848FEB" modified="2019-11-13" version="1">MKKVLKNVSFVFLLLKMCIVFGQESATQKRIVIDVGHGGKDSGAIGINGIQEKDVVLDIALEILKLNENSEMPLDIYLTRYSDTLISLTDRSKLSKALEADIFISLHCNHSDNPSARGIEVYVANATSKYSEIAVWFAFQLQDAFREQLGFESRGVKFANFQVLRETVDYCPSVLLEFGFLSSYDEAIYLTKGEKQSGIALVVLKSIIKILQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDI8</accession>
    <name>A0A5C6ZDI8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L7/L12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rplL</name>
        <name evidence="7" type="ORF">ESY86_16315</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00387">
        <property type="entry name" value="Ribosomal_L7_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00368">
        <property type="entry name" value="Ribosomal_L7_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000206">
        <property type="entry name" value="Ribosomal_L7/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014719">
        <property type="entry name" value="Ribosomal_L7/12_C/ClpS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013823">
        <property type="entry name" value="Ribosomal_L7/L12_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008932">
        <property type="entry name" value="Ribosomal_L7/L12_oligo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036235">
        <property type="entry name" value="Ribosomal_L7/L12_oligo_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45987">
        <property type="entry name" value="PTHR45987"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00542">
        <property type="entry name" value="Ribosomal_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16320">
        <property type="entry name" value="Ribosomal_L12_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48300">
        <property type="entry name" value="SSF48300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54736">
        <property type="entry name" value="SSF54736"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00855">
        <property type="entry name" value="L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_L12_N" evidence="6">
        <location>
            <begin position="5"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L12" evidence="5">
        <location>
            <begin position="57"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD87596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="123" mass="12803" checksum="741EEE40063669E8" modified="2019-11-13" version="1">MADLKDFAEQLVNLTVKEVNELATILKDEYGIEPAAAAAVMQAGPAAGEAVEEQTEFDVILNAAGGSKLAVVKLVKELTGLGLKEAKGLVDDAPSPIKEGVTKDEAEALKAQLEEAGAEVELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDK9</accession>
    <name>A0A5C6ZDK9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_17620</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000027">
        <property type="protein sequence ID" value="TXD87253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="62" mass="6599" checksum="0DF28905D9AC484B" modified="2019-11-13" version="1">MRVAIAEPGIINTQLASAFSVDQKSFHPHSKRLGVLYSASLQTSTAATLVADQILEIAESNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDM3</accession>
    <name>A0A5C6ZDM3_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UPF0102 protein ESY86_15300</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_15300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the UPF0102 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00048">
        <property type="entry name" value="UPF0102"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003509">
        <property type="entry name" value="UPF0102"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34039">
        <property type="entry name" value="PTHR34039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02021">
        <property type="entry name" value="UPF0102"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="119" mass="13877" checksum="F5ED91402ED434FB" modified="2019-11-13" version="1">MAQHNELGKKGELIAYDFLISHGYKIVARNFIYERAEVDIMALKDDILAVVEVKTRTSANFGDPQQFLKPKQMQRIIKAVDYYVNEHEMDVEVRFDIIAIVLNKKGMSLEHLENAFYHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDU0</accession>
    <name>A0A5C6ZDU0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cytochrome P450</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_14395</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="SSF48264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="444" mass="52042" checksum="A53C0CC79574E271" modified="2019-11-13" version="1">MTESQKIPEVSIFRFIRDSINILKNPLPFHLKNFQEKGDTFKLKIGLKNYVIFSRDAAFAEYVLQKNHRNYTKSKIQTVDLVKYVGRGLLTSEGELWKKQRQLIQPAFHKKQLANLLDTVLEAIQTEYKRIPTGKKMDVFPIFNDLAFQTVVKSLFSAAANPDDIKHLQHITESGQQMLVKELRQSYLVWWFKASGILKKHLDLVQEARQILKNIVYARRASGEPQDDLLDMLLEARYEDGNYMDEEQLIDEILILFTAGHETTSNALTFIFQLLALHPEWQEKIFEEIKSNENERHDLMAFVMKSKVCQQVIEEGMRLYPPAYFIDRVNVEEDTFEGKIFEKGSNLLFSVYEIHRHPELWDRPLEFRPERFEEGSRKFSSHYFPFGAGPRKCIGNNFAMFEMIIAVTELIQNYKVFPEFETIEITPLITLKPKNALLKFEKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDV2</accession>
    <name>A0A5C6ZDV2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_15740</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="412"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="187"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="581"/>
            <end position="667"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD87762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="667" mass="76854" checksum="193E5FE4D0167372" modified="2019-11-13" version="1">MLVRKNKLIILLVGFILCVLSSCRRKTPNHNEIKSFNDSVNYYLKQNRALSKAKTLNDLIENDSLKKENALKIAFQAFKNSDTLLFENSNKQALRLSIELKDSSGVAETHWNSGSFFARQEILDSAYYHYYQAHKYYSLIGQENYSAKMLYNMAFIQSRLKDYTSSEAKLFQAISTYKNIGKDLALYKCYNALGNNYSELGDFENSIEYHTKSIKVLENIDDKNKPYYERTLNDIGLTYQIKKDYNTSIQTFRKALDNKNIKNQDIRLYARLKDNLAYSKLLYGDTVNVEDYFLEALKIRDSLNNISGITINKIHLAEYYAKTNDTIKALEYAEDANKLAIKSSNNNDILSSLLLLSKIDKINSSKYLQSHVKLTKELQGYERKLKNKFARISFETDEYIHKNERLSLQKTLILSIAIGVISILTLLYYLRIQKTRNKQLVLEKQQQKANEEIYKLMIKQQSKLEEGRLKERCRISEELHDGVLGKIYGARMGIGFLNLNGESEDLKKHQKFLEDLQSIEGEIRDISHELKNEILSSNTDYLAMIESLVLENSLIGKFKYDIIAEETLFWNDSNEGIKINMYRIIQEALQNIVKHSKATHVALKFEYNNFLYNVVITDNGVGFNTSKRKNGIGLSNIKSRVKGLNGSLTLNSDSKSGTIIEIKIPSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDY6</accession>
    <name>A0A5C6ZDY6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2975 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_13675</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021354">
        <property type="entry name" value="DUF2975"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11188">
        <property type="entry name" value="DUF2975"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="103" mass="11708" checksum="57CB8D43BBAA4A6A" modified="2019-11-13" version="1">MAIWLLKTSIFYLVIKVFSILSLDRPFDLKVTRLVSKIGYFAFSMGIVALIAEGYSKDILKRGAVFQFNWGASEYVFMAGLIYIVAVLFKRGIDIQTENELTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE54</accession>
    <name>A0A5C6ZE54_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Fumarylacetoacetase</fullName>
            <ecNumber evidence="4">3.7.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">fahA</name>
        <name evidence="10" type="ORF">ESY86_17105</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid degradation; L-phenylalanine degradation; acetoacetate and fumarate from L-phenylalanine: step 6/6.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.7.1.2" evidence="4"/>
    <dbReference type="EMBL" id="VORO01000025">
        <property type="protein sequence ID" value="TXD87389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00139">
        <property type="reaction ID" value="UER00341"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004334">
        <property type="term" value="F:fumarylacetoacetase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006559">
        <property type="term" value="P:L-phenylalanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006572">
        <property type="term" value="P:tyrosine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005959">
        <property type="entry name" value="Fumarylacetoacetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015377">
        <property type="entry name" value="Fumarylacetoacetase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036462">
        <property type="entry name" value="Fumarylacetoacetase_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43069">
        <property type="entry name" value="PTHR43069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09298">
        <property type="entry name" value="FAA_hydrolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="SSF56529"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63433">
        <property type="entry name" value="SSF63433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01266">
        <property type="entry name" value="fum_ac_acetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0585">Phenylalanine catabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0828">Tyrosine catabolism</keyword>
    <feature type="domain" description="FAA_hydrolase_N" evidence="9">
        <location>
            <begin position="25"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="FAA_hydrolase" evidence="8">
        <location>
            <begin position="133"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF09298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD87389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="430" mass="48421" checksum="8E8B2CB9615BDFE2" modified="2019-11-13" version="1">MPLSANNPDRSSWLHVSKNSDFPIQNIPFGVFLTRDDIITIGTRIGDTAIDLGALHQLGYFEGIPLTDDIFLQDTLNDFIADGRKTWRLVRNRIAEIFDSNNTKLKNNLKHKEIVCFRLDEIEMQLPVQIGDYTDFYSSIEHAKNVGTMFRDPENALMPNWLHIPVGYHGRSSSIIPSGIPVHRPQGQTMPADSDTPVFGPSKLVDFELEMAFITTDANDLGESIPVNEAEEYIFGLVLFNDWSARDIQKWEYVPLGPFLAKSFASSISPWIVTLDALEPFKIDGPKPIKPQLPYLQFKGKKSYDINLEVSLKPKGAKESILSKTNFKYMYWNMSQQLAHHTINGCPVNSGDMMGSGTISGATPDTYGSMLELTWRGEKPIKMSDGTERKFINDNDTVIMRGYCEKDGTRIGFGEVSTQLLPIFNPKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEE4</accession>
    <name>A0A5C6ZEE4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_13850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022932606" evidence="1">
        <location>
            <begin position="21"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="194" mass="23372" checksum="C770FE1B13624D15" modified="2019-11-13" version="1">MMKFRLIVLLLGCFMLKVSAQKKNEKESRIELSNFPKEAQVLLQQLPEGTKRIRFYKETDGDKTSYESKFKYKGHWYSLEFNPNGKLEDIEKKIKPSKIQKQQMLAIEDYLKNNFEKYDFIKIQEHYRYNGNMVVKVFMDRVISEKHQFQPSYEIIAYLKTDKKWLLKELTFDPTGTFIKARQLTVKSYEYILY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEF8</accession>
    <name>A0A5C6ZEF8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PKD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_13445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000033">
        <property type="entry name" value="LDLR_classB_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022409">
        <property type="entry name" value="PKD/Chitinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000601">
        <property type="entry name" value="PKD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035986">
        <property type="entry name" value="PKD_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00135">
        <property type="entry name" value="LY"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00089">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49299">
        <property type="entry name" value="SSF49299"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50093">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKD" evidence="1">
        <location>
            <begin position="56"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="365" mass="39500" checksum="74E64008268C552E" modified="2019-11-13" version="1">MGLGSCFVSCTDDDFPVPAASTVPKFTYTIDNDEFAPATVTFTNTSIVPQAVGEPTYYWNFGNGDSSTEVSPSYTYLEAGAYEVKLVVTTSASLEVREEIITLVVKDPNAVGTPIYFTNGNQLFQGLINDQAPIFTPLADVAPQAAYEIVYNASDEKLYISDLDAGKIYRCNTDGSDFEDFRSGLSDPIGMAIDYDADKLYWTTGSGIQSTDLGSTDVNDREDFVTGQTNDPEGVAIHAPSGKLFWGNYSGGIWSKNLDGSNETLVIPDIETGSMSVIGDRIYYDEYVGSGDIRIKSAALDGTNITTIATGIGRVVYGIGFDASENKMYWGDRDTDALMRANLDGSETELYYQASSDTRGIVIIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEN9</accession>
    <name>A0A5C6ZEN9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_14210</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="73" mass="8504" checksum="B865867964BC3099" modified="2019-11-13" version="1">MKFTFQNENKTTHTWKSISEKQVETLPLLVFMNDKFKKSFDCLHPEKKSGASMAFTPTLYISYKVWCMSCDVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZET7</accession>
    <name>A0A5C6ZET7_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase_M43 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_15615</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008754">
        <property type="entry name" value="Peptidase_M43"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05572">
        <property type="entry name" value="Peptidase_M43"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023116974" description="Peptidase_M43 domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M43" evidence="2">
        <location>
            <begin position="400"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="821" mass="93334" checksum="4C476D8CE7FF712A" modified="2019-11-13" version="1">MKPKFILILWLTLMLVMPVEAQNFTDNFKKESVNDAPSQWRNEKGIGLIGELDGKKVIKLDRDTFVKPRVNGQDTNYLGDAFTIEFDAFFDENKIPTRQSYIINLWEGTGVHGENGKHTDPYFIYRHGIYVAGSFKNTKKIKELAVVTKTWRHIKVDYAQNTLKIFIDDQLVHHQPDLFYKPTMVSIGATNVDGPSGITNFSLIGETEKNLDGGCSAVPTEQQLAVLADSTSLFNKRLKFLEKFSIDELRGLSTLEFRNNEFIMPTRFRFSTSPTDTYSTIPIVAHIVRNSSRQDGMTIDNLNLVITNANRLYDKYGVKLYLDKVIFINDDDLFKTVYKNEDSNDDGINDEVLILDVPDRNIKKKLNIYFVPSTQGTNAGSTPSWSNFPAKSNRDQHIIMNNSHTANGQAEVLIHEIGHWFNLLHTHETSKGREMPNGVNCFYAGDFCCDTPADTNLSGKVDDNCNYTANERDSFGFFYNPDPTNFMSYSKPECMDRFSDKQIKRMYNAYFGMEQDRGYTFQVDGQLGEEIISYNWTSGWNHIEYFEIDDKPFMYFFKTSTGELAIHKVNDDGTKGAKTGIGSYGNDWSTAKIIITSRGNYLFYMKHHNGEYQIRQIKPNGSAGQVTSGRLDPGKWTPLYASISKNYLILIDKENSKIQTYFLNSDGTIGNRLYEKQLTKGFDKNSIKGSKIIRYSSSNGKYMILDLAVDGSLKEHTTIQTISSGFSTMDFSSIYDDFYVTTDSFHNMVFLNESSGQIQLHQWKADNTIGENWYDSNNVMSNLPGYDVLTPYNISNNNGKSSYLMISNSTSGNAIVYKLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF13</accession>
    <name>A0A5C6ZF13_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Heavy metal-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17405</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0145 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000026">
        <property type="protein sequence ID" value="TXD87337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002765">
        <property type="entry name" value="UPF0145"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035439">
        <property type="entry name" value="UPF0145_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01906">
        <property type="entry name" value="YbjQ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117782">
        <property type="entry name" value="SSF117782"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="104" mass="11637" checksum="739AB7F49B06565F" modified="2019-11-13" version="1">MARSVNVFYNGSYSNRHERDARASRENMCFAQIRIQTLNLGGNAVIATDIDFSEVGAAKGMLMVCMAGTAIKLNNTDILEKEKTEILDKLSYANQRLKELSKFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF42</accession>
    <name>A0A5C6ZF42_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Phage tail sheath family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_17060</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the myoviridae tail sheath protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000025">
        <property type="protein sequence ID" value="TXD87381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035089">
        <property type="entry name" value="Phage_sheath_subtilisin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020287">
        <property type="entry name" value="Tail_sheath_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04984">
        <property type="entry name" value="Phage_sheath_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17482">
        <property type="entry name" value="Phage_sheath_1C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phage_sheath_1" evidence="2">
        <location>
            <begin position="211"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="Phage_sheath_1C" evidence="3">
        <location>
            <begin position="304"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD87381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="411" mass="45621" checksum="164BA2E5D8224C15" modified="2019-11-13" version="1">MVAMTAILFPWGLMGELKISVGTYGGVKVIPDFSIAQFLKGLGVVETISEITLIAIPDAVFLESSDCFQLQEAMVAQCEKLQNRFAILDVYSGNESIASSANPIKNFRTQLNARALNYAAAYYPWLHTGLKSHTDVDFTNLNERSKVLLRQICEQFISKNFNASEAKAIKPYLDCIAKPMQSIPTISVQQLLTSEEAHKKLNQIIPDYKQIMLALLKQENLMPPSAAMAGVYTVMDKTRGVWKAPANVGVVGVVAASVRIDSQQNQALNVDVSGKSINAIREFPNRGIRVWGARTLDTNLLETRYINTSRTLISIKQSVKCALKPFAFEPNDQNTWQRINGMVENYLNTFWREGALAGLKVEQAYFVTIGLNRTMSQQDINAGLLKLELGVSFTRPAEFSVIRIVQKMGAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFH3</accession>
    <name>A0A5C6ZFH3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">M20/M25/M40 family metallo-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_14995</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="PTHR12147"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022681775" evidence="1">
        <location>
            <begin position="20"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M28" evidence="2">
        <location>
            <begin position="91"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="386" mass="43155" checksum="2A7212552D9EB8F3" modified="2019-11-13" version="1">MKNLLITGLLLLFVSLSKAQTFNTFYAEVVANISESNLLSDLTTFEKFGVKTVGSPALTHTENWISHRYESMGYTDVVLQPFTYRKGSSNNIIVTKTGTIYPYTFLIIDAHYDTINGPGTNDNGTGTVLLLEMARLLKDVETEYSIKFIHFSGEEDGLIGSKFYVKNTVVPENMDIKLVFNIDEVGGVSGLTNDTVVCEQDLGAPTFNNAASSAATESLAILMGLYSTLNTQISKTYGSDYMPFENNGEIITGLYEKNISPVNHSANDNLENMDVGYFYEVVRGAIGAAMEFAVAYETSSLVEQKYYERILKIYPDPSNSYLNIEFDEPLEDEVEFKLMDRLGKEIYTKTISEQNFRFATDFIASDTYEAVFKMGNKRFVKTVVVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFJ5</accession>
    <name>A0A5C6ZFJ5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Alkane 1-monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ESY86_12630</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(3+)</name>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell inner membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the fatty acid desaturase type 1 family. AlkB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03512">
        <property type="entry name" value="Alkane-hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033885">
        <property type="entry name" value="AlkB/XylM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005804">
        <property type="entry name" value="FA_desaturase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38674">
        <property type="entry name" value="PTHR38674"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00487">
        <property type="entry name" value="FA_desaturase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7 10" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="7 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="130"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="208"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="231"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="317"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="FA_desaturase" evidence="9">
        <location>
            <begin position="101"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD88360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="347" mass="40265" checksum="DA072D1CD25540C8" modified="2019-11-13" version="1">MKDLKYLAAFSIPLVAFISLYFKGAFVFLTPVYAFILIPIFELIFTVDPKNLSSEEHNARLKRKVFDWLLYLNLPIVYVLIGFGIYQITQQPLATYEIVGIVISVGIVLGVNGINVAHELGHRHTTNERFLGKALLLPALYMHFFIEHNYGHHLHAATAEDPATARYNQTVYGFWFTSVFRQYVNAWSIQKTLLKNSGRPFLSLKNDMFWYSILQLVYLAMCFLFFGKMALIFVISAAIVGILLLETVNYIEHYGLLRLKTKSGRYERVQEMHSWNSNHVIGRIVLYELTRHSDHHFKSTKKYQILDCHDESPQMPFGYPTSMVLAMVPPIWFKIMNKRVPRQMLLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFL2</accession>
    <name>A0A5C6ZFL2_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7 8">Elongation factor Tu</fullName>
            <shortName evidence="7">EF-Tu</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">tuf</name>
        <name evidence="10" type="ORF">ESY86_16280</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01884">
        <property type="entry name" value="EF_Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03697">
        <property type="entry name" value="EFTU_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00118_B">
        <property type="entry name" value="EF_Tu_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041709">
        <property type="entry name" value="EF-Tu_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033720">
        <property type="entry name" value="EFTU_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004541">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_bac/org"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004160">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03143">
        <property type="entry name" value="GTP_EFTU_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="SSF50465"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00485">
        <property type="entry name" value="EF-Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 7 10" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="5 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="9">
        <location>
            <begin position="10"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="19"/>
            <end position="26"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="81"/>
            <end position="85"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="136"/>
            <end position="139"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD87590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="395" mass="43130" checksum="3F2E4CA2321284AF" modified="2019-11-13" version="1">MAKATFDRSKPHLNIGTIGHVDHGKTTLTAAITKVLADAGFSEARSFDQIDNAPEEKERGITINTSHVEYATANRHYAHVDCPGHADYVKNMVTGAAQMDGAILVVAATDGPMPQTREHILLGRQVGIPRMVVFMNKVDMVDDEELLELVEMEIRDLLSFYEYDGDNGPVIAGSALGALNGEQKWVDTVLQLMESVDSWIEEPLREIDKPFLMPIEDVFSITGRGTVATGRIETGIAKTGDPVEIIGMGAEKLTSTITGIEMFRQILDRGEAGDNAGILLRGIEKTQISRGMVIVKPGSVTPHAKFKAEVYVLKKEEGGRHTPFHNNYRPQFYVRTTDVTGNIMLPDGVEMVMPGDNLTITVELIQSIAMTVGLRFAIREGGRTVGAGQVTEILD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFN9</accession>
    <name>A0A5C6ZFN9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TVP38/TMEM64 family membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_16460</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TVP38/TMEM64 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="SNARE_assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015414">
        <property type="entry name" value="TMEM64"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12677">
        <property type="entry name" value="PTHR12677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="SNARE_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="69"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="104"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="178"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="210"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU366058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="234" mass="26152" checksum="EB4CD67DCB2E613A" modified="2019-11-13" version="1">MEKEKDKQQPSKSKWPLYISLLVVGALVASYYLIEEVQQFINNAWTVLTSDDDQRITAWVDGFGWFGPIVLVLAMIVQMFLLVIPSVLLIVVSILAYGPIWGSAIVFVAVFAASTVGYVMGSYIGKTFVLKILGQSTKNKIEDFIEHYGFWAVIVTRLNPFLSNDAISFVGGMLKMGYWRFIGATLLGIAPLTILIAIMGKSNDTLKTGLLWVSLISLALFIMYYLYNRTKNKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFP2</accession>
    <name>A0A5C6ZFP2_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Maltokinase</fullName>
            <ecNumber evidence="3">2.7.1.175</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Maltose-1-phosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_11450</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + D-maltose = ADP + alpha-maltose 1-phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:31915"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17306"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:63576"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.175"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the aminoglycoside phosphotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.175" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040999">
        <property type="entry name" value="Mak_N_cap"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18085">
        <property type="entry name" value="Mak_N_cap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mak_N_cap" evidence="6">
        <location>
            <begin position="42"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF18085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD88844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="543" mass="64024" checksum="33E5FDA523953A6D" modified="2019-11-13" version="1">MAKQEIKSANLSSTFSFSDKWETLLENKEFIKVFLSDVLENYIVKQRWYGGKASRMKYIELAEYFRIQQHDEVYYGLILEVNFTEAFYQHYFLPIAFVSDDSFAQDDRILPISIQDQEGFIIDAINLEAFRKLVFQRLLTAVAKDKTRVRYHKSELFKDCQYENSRFMGLEQSNTSIVYNEKYVLKFFRRIYSDRNPDYEMSKFLSEKKDFKNTPAYLGSIQIKDIEGTNITIGLMQEMVENQGDAWQYMLSELHKVFCNLEYKNIDIKSLPKTVDFGQLQIQDVPAQIIDWVGLNIFTKIQTLAMRTAEMHIALGSEFEETAFAPTHFNEDYTVWLKNRLLYQFQNRLNTIENSLHKLDGLALELANEFLEKKNIIRRRFVNFDWTKLKGERIRVHGDYHLGQVLIKGDDFYILDFEGEPESTIRDRKVKQPPLKDVAGLFRSFHYAIYATIFNNMETYTHSQEDLFEAAEVLYQYLKGVFLGVYTIKVQEANLNIGYEQERIFLLKYAMLEKAVYELGYELNSRPRWAIIPLKGISNIINN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFX3</accession>
    <name>A0A5C6ZFX3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">T9SS type B sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_16695</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000023">
        <property type="protein sequence ID" value="TXD87531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026341">
        <property type="entry name" value="Bac_Flav_CTERM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035986">
        <property type="entry name" value="PKD_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49299">
        <property type="entry name" value="SSF49299"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04131">
        <property type="entry name" value="Bac_Flav_CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="776" mass="84951" checksum="FDA7F1A6C3ABDA19" modified="2019-11-13" version="1">MKAFPQILCGLLTACSFGQNIQVDSQTYTPQQLVENILIDSDCIDNVEVTYVLGGDFGTTDRSYGYFEAAGSSFPFESGIVLSTGKLANVRGPNSSLSDDNATNWAGDADLEAVLNENNTTNATIIAFDFTSAASQISFRYIFASEEYQEGNPNTCQYSDLFGFLIRPANEQTYQNIALVPDTQIPVKVTTVHPTIPGACEAQNEAYFESFNGQDAPINFNGQTKILTATATLVPNQTYHVKLVIADEQNYRYDSAVFLEAGSFKLSTDLGPNRLIDSANSLCEGESIALDASASNANSYKWFKNNTLLPMETSQTLNVAEAGIYTVEITLDNSCISFGKVIVEVSPKPTPTNSVLIACDQNQDGLTYYNLFDAEESIVNQSPNSVVSNFYLTQNDAFEAENYIANATSFENTSPSQIVFARVQNSAGCIEVAELELQISNTSLNIATLEACDGEMVDGIADFNLNEITASFESQIPTNASVSYYLTEEDAFSENNPLDTNFQNDVVDFQTLFVKVESNNQCFAISEVNLKVLGTPIVEADETVYYCSSDFPETVTLEGGVLNDLPSNYYYEWQFNGNASSVNTSFFEANQAGVYTVTLTDPNGCATSRTITVEASTLPIIEDILITEGSQNNSITVITSTPRNYGYALDDPNGSFQGSETFTNVAPGFHKVYVRDSHGCGIAEKLISVLGFPRFFTPNGDTFNERWQLYGVNSDFNQGIEIQIFNRYGKRITQLNNTSAGWDGTLNGQALPSDDYWFLATLIDGRTFTGHFALKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFX8</accession>
    <name>A0A5C6ZFX8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hemerythrin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012312">
        <property type="entry name" value="Hemerythrin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01814">
        <property type="entry name" value="Hemerythrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hemerythrin" evidence="1">
        <location>
            <begin position="39"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="153" mass="18539" checksum="7496A5A3EDB5132D" modified="2019-11-13" version="1">MKDKPQKRHKALQPLSRQHHHGLLLSWKIRSGFNKDVAPARIRVYADWFYENHLIPHFEVEEKYIFPIIGNDHEKVKSALADHRRIKRLFAEKNEDTKTLSKIEEELEQHIRFEERVLFPEIQKVATEEQLRYIETIHQPEDFVDKSDDEFWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG22</accession>
    <name>A0A5C6ZG22_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_11650</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="49"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="130"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="163"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="245"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="279"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="303"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="338"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="368"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="1"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD88620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="404" mass="43709" checksum="AE5AA9B9F1A942EB" modified="2019-11-13" version="1">MKHAKFILPAIVISQFCCTSLWFAGNAVINDLVLNYELSPSALGHLTSAVQFGFIIGTLLFAILTIADRFSPSKVFLISALLGSLFNLGIIWEDNSLMSLLSLRFLTGFFLAGIYPVGMKIAADYYEKGLGKSLGFLVAALVVGTAFPHLLKGITDTFPWKSVLLATSSLAVLGGLLMFILVPDGPYRKPSQRINPTAFLSVFKNREFRSVAFGYFGHMWELYAFWAFVPIMLKKYSVEHSQALFNIPVLSFIVIGVGGLACIGAAYMAQSVGTKRTAFTALFLSCACCLMSPLLFASASEGLFIGFLIFWGMVVIADSPLLSTLVAQNAPAEIKGTALTIVNCIGFSITIISIQFISSMIALTASNSIYIILAIGPILGLFALRKKHKVTVPNGEHSSKKSNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG29</accession>
    <name>A0A5C6ZG29_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Isopenicillin N synthase family oxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_11710</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the iron/ascorbate-dependent oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026992">
        <property type="entry name" value="DIOX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044861">
        <property type="entry name" value="IPNS-like_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027443">
        <property type="entry name" value="IPNS-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03171">
        <property type="entry name" value="2OG-FeII_Oxy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14226">
        <property type="entry name" value="DIOX_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="2">
        <location>
            <begin position="168"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="315" mass="36352" checksum="9D84B4AF5E727327" modified="2019-11-13" version="1">MTKIPSVDLRDFLSDDPDRKQKFINEIGKAYEDIGFVALKGHFLNDALVDQLYEEIKQFFNLNLETKRKYEIEGINGQRGYVSFGKESAKGRKVGDLKEFWHFGQYVEDDAERAKEYPENVKVDELPEFNKVGKETYQMLEKTAKYVLRSLALFLELEETYFDNVIHNGNSILRPIHYPPILTEPETAERAAAHGDINLITLLMGAQGKGLQVQNHKGEWIDAMAEPDEIMINVGDMLSRHSNNKLKSTIHRVVNPPRELWGTSRYSIPFFMHPISEMKLDVLESCIDEDHPKQYEDITAGEFLDERLKELGLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG38</accession>
    <name>A0A5C6ZG38_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">FAD-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_11775</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-linked_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="SSF55103"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="5">
        <location>
            <begin position="37"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="618"/>
            <end position="650"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD88640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="975" mass="108194" checksum="71A9C113E919B969" modified="2019-11-13" version="1">MTKLPKQALDDLRLQLSGELHSDHLMKALYATDASVYRMLPLAVAFPKNKADLKLLIDFAKTHQTSLIPRTAGTSLAGQCVGKGIVVDVSKHFNKIIDINEREKTATVQPGVVRDELNQALAPFGLFFGPNTSTSNRCMIGGMVGNNSSGTTSIQYGVTRDKVLELKTFLSDGSEVVFSEMASEGFENKTKLNTLEGHIYRTLYAELSPEAVQNEIIAEFPKPEIHRRNTGYAIDELIKTEIFSQEGLPFNMCKLLTGSEGTLAFTTQITLKLDQLPPKEPLLVAAHFRSIADCLNAVSLVMEHDLYTCEMMDKTILDLTKHNKKQEENRQFVEGDPEAILMCEIRASSKTEAAKKAGALLASLQQSQLSYANPVLSGDDIDKAIELRKAGLGLLGNLIGDQKTAACIEDTAVALPDLANYVADFSKLMESYKQKPVYYAHAGAGELHLRPILNLKKKSDVVFFRKITTEVAHLVKSYKGSMSGEHGDGIVRAEFIPLMIGQANYQLLKQIKSAFDPHNIFNPGKITDALPMDENLRYVPDRIEPEVETLMDFSSSLGILREAEKCNGSGDCRKLPQFGGTMCPSFRATRDEKDSTRARANALREILTQSDKKNKFDHEELKDVFDLCLSCKACATECPSSVDVASLKAEFQYQYQKANGISLRTKLFAYNNSLNGFGSYVPRLTNFLFSNVLTSAILKKSFGIASERSLPLLSTQSLYKWFHCIENQNYRENYKKTIYFFVDEFTNHLDANIGKDAIELLTALDYEVKVIDNEESGRAFISKGLLEKAKDLANKNIALFKDKVSAETPLIGIEPSAILGFKDDYLRLANDKTSAENIAKHCYLIEDFIAMEIDLGHIGPDQFSDEIKTIKFHGHCHQKALTNQLSSFKVLNLPKNYKVSIIPSGCCGMAGSFGYEKEHYELSMQIGEQTLFPAVRKASASVVISANGTSCRHQIKDGTSREALHPITVLRRALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG40</accession>
    <name>A0A5C6ZG40_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNA-binding transcriptional accessory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_15340</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05685">
        <property type="entry name" value="S1_Tex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.650">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3500.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041692">
        <property type="entry name" value="HHH_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003583">
        <property type="entry name" value="Hlx-hairpin-Hlx_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044146">
        <property type="entry name" value="S1_Tex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023323">
        <property type="entry name" value="Tex-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023319">
        <property type="entry name" value="Tex-like_HTH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018974">
        <property type="entry name" value="Tex-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032639">
        <property type="entry name" value="Tex_YqgF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006641">
        <property type="entry name" value="YqgF/RNaseH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037027">
        <property type="entry name" value="YqgF/RNaseH-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17674">
        <property type="entry name" value="HHH_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09371">
        <property type="entry name" value="Tex_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16921">
        <property type="entry name" value="Tex_YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00278">
        <property type="entry name" value="HhH1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00732">
        <property type="entry name" value="YqgFc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1 motif" evidence="2">
        <location>
            <begin position="641"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="158"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="711" mass="79184" checksum="26DA74C2493A3F51" modified="2019-11-13" version="1">MQLIPYIISQTKLPEASVKNTVNLLNQDCTIPFISRYRKEATGNLDEVQIGDIVKFKDAFETLEKRKLAILKALEDQEVLTADLKAKVNACQDSTTLEDLYLPYKKSRRTKAETARKNGLEPLAKILMSQSRHVDDKGLATIAQEFITSEITSFEDALEGARHIIAEWVNERSDLRNQLRNQLQRHAMIATKVIKAKKDEEKAQKFRDYFEWEEALSRIPSHRLLAILRAEAEGFIRVKIEIDAEHAINRIASRIIKTQDACAQQIELAISDAYKRLLFPSLSNEALQNAKQKADEAAIAIFAKNLKQLLLGSPLGEKRVLAIDPGFKSGCKLVCLDEKGDLKHNETIYPHPPKNDQTGAMKKISFLTEAHNIEAIAIGNGTASRETEALIKRMRFKNEIQVFVVSEAGASIYSASKIARDEFPNYDVTVRGSVSIGRRLQDPLAELVKIDAKSIGVGQYQHDVDQAKLQHELDVVVQSCVNSVGVNINTASHSLLSAVSGIGPKLAENIVAYRSEYGAFSNRKEIKNVTRLGEKAFEQAAGFLRIKASANPLDDSAVHPESYAIVEQMAKDEGVSLSELIGSKSKLQNISLQKYCTETVGLLTLKDIVKELEKPGLDIREQAKVFSFDQNISTISDLRVGQLLPGIVNNITAFGCFVDVGIKESGLIHISNLSDGFVKDVNEHVHLQQQIMVKILEVDEKRKRIQLKLQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG44</accession>
    <name>A0A5C6ZG44_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_10425</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="210" mass="23872" checksum="AA323667FFF409ED" modified="2019-11-13" version="1">MIKKEKMKPLCFIALALICLTCQENHRSTNQTSQTPPKELRDMAMEGITIEFIFDRNKPTHGDLFLMTGAEDPDFPPEHKQYEQLKSLGLSQIDDAYFGIPNEPGNINNELGFLLIPKQINYDGNAPFDSVLMDYVPLRSEAKRADLVKRICSEFKENLDVSILFEGEELNDLEIINDKIDAIIAYCRAELKVEPGSVEAIALLERDYTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG45</accession>
    <name>A0A5C6ZG45_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DNA-3-methyladenine glycosylase I</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_13855</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008725">
        <property type="term" value="F:DNA-3-methyladenine glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005019">
        <property type="entry name" value="Adenine_glyco"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03352">
        <property type="entry name" value="Adenine_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="SSF48150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="187" mass="21563" checksum="DC079E8B00D9F458" modified="2019-11-13" version="1">MEKPRCGWCQGDALYKAYHDQEWGVPVKDDATFFEFLVLETFQAGLSWITILRKRAHFRAAFDGFDYIKIAKYDQEKVDALLKNEGIVRHKLKVQSAITNAQAFMDIQEEFGSFTKYIWDFVDGSPLKNKLENHKNAPTNTPLSDGISKDLKKRGFKFVGSTVMYAFLQATGLINDHEINCFRYDEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG79</accession>
    <name>A0A5C6ZG79_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Iron-sulfur cluster carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_14030</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the Mrp/NBP35 ATP-binding proteins family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the MIP18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140663">
        <property type="term" value="F:ATP-dependent FeS chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02040">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002744">
        <property type="entry name" value="MIP18-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019591">
        <property type="entry name" value="Mrp/NBP35_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000808">
        <property type="entry name" value="Mrp_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044304">
        <property type="entry name" value="NUBPL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033756">
        <property type="entry name" value="YlxH/NBP35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42961">
        <property type="entry name" value="PTHR42961"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01883">
        <property type="entry name" value="FeS_assembly_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10609">
        <property type="entry name" value="ParA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="SSF117916"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01215">
        <property type="entry name" value="MRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FeS_assembly_P" evidence="6">
        <location>
            <begin position="5"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="109"/>
            <end position="116"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD88213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="379" mass="40813" checksum="23E8F65D442ED674" modified="2019-11-13" version="1">MKLNKQDILKALEHITVPGEGQNMVDSGAVKNVVTFADEVIVDITINNPSLQAKKKTEVEIMKIIHDKVYEKAKITVNVKVDAPEKSATNTIKGKEIPGIQNIIAVASGKGGVGKSTVTANLAVTLSKMGFKVGVLDADIYGPSMPIMFDVELERPVAVNIDGKSKMKPVENYGVKMLSIGFFTKQDQAVVWRGPMAAKALNQMIFDAAWGELDFLLIDLPPGTGDIHLSIMQSLPITGAVVVSTPQNVALADAKKGVAMFQQESINVPVLGIIENMAYFTPEELPDHKYYIFGKEGAKNLASDLKVPFLGGLPLVQSIRESGDAGRPAAMQTGTTLEKAFETITQNVVQEVVRRNDKLPPTEAIKITTMAGCAAVNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGI5</accession>
    <name>A0A5C6ZGI5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Radical SAM/Cys-rich domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_09190</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024521">
        <property type="entry name" value="DUF3641"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026351">
        <property type="entry name" value="rSAM_SeCys"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43728">
        <property type="entry name" value="PTHR43728"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12345">
        <property type="entry name" value="DUF3641"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04167">
        <property type="entry name" value="rSAM_SeCys"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="5">
        <location>
            <begin position="58"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3641" evidence="6">
        <location>
            <begin position="215"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF12345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD89217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="350" mass="39571" checksum="CDA7740C423AB3C6" modified="2019-11-13" version="1">MIKSLHKRESELANSNRQVEILSNGIFQNGELPKFKDKIAETGQFPLKAKKLEILQINVGYMCNQVCEHCHVDAGPDRKEIMTRDTMRQCLEVIKNTGAHTLDLTGGAPEMNPDFRWFVDEASKAGIKDFIVRSNLTIIRANKKYYDLPEFFKQHNVHVISSMPHWTKGKTDKQRGDGVFDKSIKALQELNAIGYGMPDNDLRLDLVYNPSGAYLPGNQASMEKDFKKGLSEEFNIQFHNLFAITNLPIARFLDYLIASENYEDYMYSLVEAYNPAAVKSVMCTNTLSISWDGYLYDCDFNQMLNLPVNSKVKHIADYNEELLDGRTIMISQHCYGCTAGAGSSCQGSVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGK7</accession>
    <name>A0A5C6ZGK7_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 7">Citrate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_14985</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>acetyl-CoA + H2O + oxaloacetate = citrate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16845"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.3.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate from oxaloacetate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 5 8">Belongs to the citrate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00717"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004108">
        <property type="term" value="F:citrate (Si)-synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd06114">
        <property type="entry name" value="EcCS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016142">
        <property type="entry name" value="Citrate_synth-like_lrg_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016143">
        <property type="entry name" value="Citrate_synth-like_sm_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002020">
        <property type="entry name" value="Citrate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019810">
        <property type="entry name" value="Citrate_synthase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024176">
        <property type="entry name" value="Citrate_synthase_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036969">
        <property type="entry name" value="Citrate_synthase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010953">
        <property type="entry name" value="Citrate_synthase_typ-I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00285">
        <property type="entry name" value="Citrate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001369">
        <property type="entry name" value="Citrate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00143">
        <property type="entry name" value="CITRTSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48256">
        <property type="entry name" value="SSF48256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01798">
        <property type="entry name" value="cit_synth_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00480">
        <property type="entry name" value="CITRATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="active site" evidence="6">
        <location>
            <position position="307"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR001369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001369-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD87972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="428" mass="47813" checksum="12DD7740E8C25E69" modified="2019-11-13" version="1">MSDKATLEINGKKYEFPLITGTENETAIDIKTLRSVTGGVTTIDPGYKNTGSCESAITFLNGEKGILRYRGYSIEELAEKADFLEVAYLLIFGELPTREKLDKFYTDIKKQAVVDEDIKKILDAFPKTAHPMGVLSSLTSALTAFNPSSVNVESEEDMYNAIVKIMGKFPVLVAWTLRKKQGLPLDYGDKSLGYVENVLKMMFKEPNEEYTQNPILVNALDKLLILHADHEQNCSTSTVRIVGSSHAGLFASLSAGISALWGPLHGGANQAVLEMLEGIKADGGDTKKYMAKAKDKDDPFRLMGFGHRVYKNFDPRAKIIKKSADDVLDQLGVEDPILAIAKGLEKEALEDSYFVDRKLYPNVDFYSGIIYRGMGIPTDMFTVMFALGRLPGWIAQWREMRLQKEPIGRPRQVYVGENHRPFKDISER</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGL8</accession>
    <name>A0A5C6ZGL8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptide-methionine (R)-S-oxide reductase</fullName>
            <ecNumber evidence="2">1.8.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">msrB</name>
        <name evidence="6" type="ORF">ESY86_11430</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[thioredoxin]-disulfide + H2O + L-methionyl-[protein] = [thioredoxin]-dithiol + L-methionyl-(R)-S-oxide-[protein]</text>
            <dbReference type="Rhea" id="RHEA:24164"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12314"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:45764"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.4.12"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.12" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033743">
        <property type="term" value="F:peptide-methionine (R)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030091">
        <property type="term" value="P:protein repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028427">
        <property type="entry name" value="Met_Sox_Rdtase_MsrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002579">
        <property type="entry name" value="Met_Sox_Rdtase_MsrB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10173">
        <property type="entry name" value="PTHR10173"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01641">
        <property type="entry name" value="SelR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="SSF51316"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00357">
        <property type="entry name" value="TIGR00357"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51790">
        <property type="entry name" value="MSRB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022956246" description="Peptide-methionine (R)-S-oxide reductase" evidence="4">
        <location>
            <begin position="21"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="MsrB" evidence="5">
        <location>
            <begin position="37"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD88862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="160" mass="17740" checksum="E5703437A1FD64DB" modified="2019-11-13" version="1">MKRLMAICIFALVLSCNSNAQKTATATKTDFKVSKTEAEWKKELTADQYYVLREAGTERPFSSDLNDNHREGTYVCAACETPLYKSENKFESGTGWPSFDRVIEGNVAFSTDSKLGYSRNEEHCATCGGHLGHVFNDGPKETTGKRHCINGDALKFVPAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGQ9</accession>
    <name>A0A5C6ZGQ9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">UDP-3-O-acylglucosamine N-acyltransferase</fullName>
            <ecNumber evidence="5">2.3.1.191</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">lpxD</name>
        <name evidence="7" type="ORF">ESY86_10385</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a (3R)-hydroxyacyl-[ACP] + a UDP-3-O-[(3R)-3-hydroxyacyl]-alpha-D-glucosamine = a UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + H(+) + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:53836"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9945"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78827"/>
            <dbReference type="ChEBI" id="CHEBI:137740"/>
            <dbReference type="ChEBI" id="CHEBI:137748"/>
            <dbReference type="EC" id="2.3.1.191"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Bacterial outer membrane biogenesis; LPS lipid A biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the transferase hexapeptide repeat family. LpxD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.191" evidence="5"/>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00973"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016410">
        <property type="term" value="F:N-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03352">
        <property type="entry name" value="LbH_LpxD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00523">
        <property type="entry name" value="LpxD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007691">
        <property type="entry name" value="LpxD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020573">
        <property type="entry name" value="UDP_GlcNAc_AcTrfase_non-rep"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43378">
        <property type="entry name" value="PTHR43378"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04613">
        <property type="entry name" value="LpxD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01853">
        <property type="entry name" value="lipid_A_lpxD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2 5" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="1 5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="4 5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="LpxD" evidence="6">
        <location>
            <begin position="21"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD88898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="342" mass="36875" checksum="626006BAA93C3215" modified="2019-11-13" version="1">MNFTAQQIAGILEGDIVGNPDVEVSRLSKIEEGTEGSLTFMANPRYKSYMYSTKASIIIVNRTFEPESEISTTLIKVDDAYKAFSKLLEFYNQIKLNKEGIEQPVVIADSAILGKEHYVGAFSYIGEHVRIGKNVKIFPNTYIGDNVKIGDNTIIFAGVKIYAACVIGNNCVINSGAIIGADGFGFAPNGDGEYIKVPQTGNVILEDFVDIGAATTIDRATLGSTIIRRGAKLDNQIQIAHNVDIGRNTVIAAQTGVAGSTKIGENCQIGGQVGIVGHITIGNNVKIQAQSGIGRNIQDNEIIQGSPALGYGDFNKSYVHFKNLPKIMKRINDLEKKLNGDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGR0</accession>
    <name>A0A5C6ZGR0_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytosine-specific methyltransferase</fullName>
            <ecNumber evidence="8">2.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">dcm</name>
        <name evidence="10" type="ORF">ESY86_14230</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = a 5-methyl-2'-deoxycytidine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:13681"/>
            <dbReference type="Rhea" id="RHEA-COMP:11369"/>
            <dbReference type="Rhea" id="RHEA-COMP:11370"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:85452"/>
            <dbReference type="ChEBI" id="CHEBI:85454"/>
            <dbReference type="EC" id="2.1.1.37"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.37" evidence="8"/>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003886">
        <property type="term" value="F:DNA (cytosine-5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018117">
        <property type="entry name" value="C5_DNA_meth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041657">
        <property type="entry name" value="HTH_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12728">
        <property type="entry name" value="HTH_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00105">
        <property type="entry name" value="C5METTRFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00675">
        <property type="entry name" value="dcm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00094">
        <property type="entry name" value="C5_MTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51679">
        <property type="entry name" value="SAM_MT_C5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0680">Restriction system</keyword>
    <keyword evidence="4 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HTH_17" evidence="9">
        <location>
            <begin position="7"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD88043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="414" mass="47051" checksum="7F722A475DE8EB54" modified="2019-11-13" version="1">MVIKEHYSLSEAAEILGKSKETLRRWDRDGKLTALREPISEYRLYKKEEIDSLIKPLFDNIEDETDNSENPIKEFKVLELFAGAGGLAIGLEKAGITCAALNEIDKWACQTLRENRPHWNVLEGDIKNYNFEKFNGKVDIVTGGFPCQAFSYAGKKLGLEDARGTLFYEFARAVQEVNPPICIGENVKGLLSHEKGDTLRGMISILDEIGYNVVPVKVLKAVNYKVPQKRERLIVVGVRKDIDLKYEYPQAYQSIYNLSDALKKGKLYDSDVPKSEGSTYPEHKKAVLDLIPPKGYWRDLPLDLQKEYMGKSFYLGGGKTGMARRIGWDEPSLTLTCSPAQKQTERCHPEETRPFTVREYARIQTFPDEWKFMGSVSQQYKQIGNAVPCNLGKEIGYSIIKFLNAYYLSESKPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGS3</accession>
    <name>A0A5C6ZGS3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PASTA domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_12275</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005543">
        <property type="entry name" value="PASTA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03793">
        <property type="entry name" value="PASTA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00740">
        <property type="entry name" value="PASTA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51178">
        <property type="entry name" value="PASTA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="PASTA" evidence="2">
        <location>
            <begin position="41"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="PASTA" evidence="2">
        <location>
            <begin position="110"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="183" mass="20699" checksum="B5C17DAC04BF64BD" modified="2019-11-13" version="1">MSFLRFVKSKAFFTQILIAIVALVVIVFLTLQWLDYTTNHGEFIKVPDLTGQSLSTVETELDRADLTMEIQDSANFNPDYPRFSVIEQYPLAGTQVKENRKIYLTLNPSGYRKMEIPNVVRRTFRQAKPTLETLGFQIGSITYVDDIGKDEVIAIKHKGKTLEQGDLLALNSKIDVVLGNGNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGY5</accession>
    <name>A0A5C6ZGY5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">OmpH family outer membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_14660</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Skp family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.910.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005632">
        <property type="entry name" value="Chaperone_Skp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024930">
        <property type="entry name" value="Skp_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35089">
        <property type="entry name" value="PTHR35089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03938">
        <property type="entry name" value="OmpH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00935">
        <property type="entry name" value="OmpH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111384">
        <property type="entry name" value="SSF111384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022747012" evidence="5">
        <location>
            <begin position="22"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="174"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="57"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="179"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="264"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="292"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD87909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="346" mass="40109" checksum="D41BE3B35A6FFC4D" modified="2019-11-13" version="1">MKRNVLFLLTLISLSCFVSNAQRGVRIGYIDTEYILENVPEYTEANTQLDQKVQQWKTDIEQRLNTIESKKKQLNGERVLLTQQLYEERLEDIGFEEAEILDYQQKRFGPNGDLMIQKQQLIQPIQDQIFAAVQEIAENKKYDFIFDKSADVVMLYSAERYDISEMIIRSITRSAKRTQATSRSERREAEREEVVPEINEAMDEREKVLEERQTAREAAMDERNAERLKRRDSLKDAAAARRQSILDERAAAKAARDSVSGESASPDVERNTVVEDSTKATGATEATTSKTPEQLAEEKRQEKLTDREERKKALEERKKKILEARKKAKEEREAARNEEEPDEQVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH11</accession>
    <name>A0A5C6ZH11_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_13020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydrolase_4" evidence="1">
        <location>
            <begin position="83"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="323" mass="36067" checksum="068F845EF29B197E" modified="2019-11-13" version="1">MCTATYVLKRKRLYLLLLFMFCFIHFGMSQSEIISEEILISNDSIQLPGTLTFHTGETKQPLVIFVHGSGNVDRNGNQAGAPSSANYIKQLSDSLVSKNIAFYRYDKRSATASNVPFMMKDMRFYAFTEDVNLAIAHFMDDTRFSSITLIGHSQGSLVAMLANHEHVDKYISIAGPSTSIDKALIEQVRARNGDSLANLVVSHFKELQDTGSIAKVDPNLMVLFNKPTQPFMASWMAYDPSEELKKLEMPILILNGDKDLQVAVVDAETLHKAQPNSKLVIIKDMNHVLKTIVDDYDNFISYTKPDFPLSSALVDAIAAFIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH94</accession>
    <name>A0A5C6ZH94_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">SLC45 family MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_13190</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="82"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="143"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="192"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="262"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="339"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="364"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="388"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="421"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="456"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="271"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD88259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="485" mass="54198" checksum="D3A29FA8060EFD91" modified="2019-11-13" version="1">MKFTKPKLSFWQIWNMNVGFFGIQFSFGLQQTAINPIFSFLGAHNEELPLLNLAGPVTGLIIQPLIGAISDKTWSPRWGRRKPFFLIGAIVASLCLFMFPFSSELWFAVGLLWVLDAGNNTAMEPYRAFVGDKLPDVQLTYGFQMQSLFVGAGITLANFSLFLFQDWFSVPIVEGASLCTAGNEVVSAIPTWVYYSFFLGAIMSIGTILWSVLKTPEIPPSDEELKFIRDRNKDSSFAHRVFEPFIEIYSALGKMPVLMKKLAGVYLFQWYALFVYWQFITPMLRVSMFGISNSDTQRFDGIMAACNSGAEITAADTSFAQNFQFLSEQALAQTGLMNGTYNMVTMLVALVLVPIAAKYSNKAVYVGSLFLTGIAMLSMPYIEDPYLLLLPMILFGIGWAAMMGIPYAMVSKVIPKERRGVYMGIVNMMIVIPMGIQTLTFGFIVKHFLGNSAVNAILFGGVFFIIASLLALRIKRQKEDYLTFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-02-10" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHJ8</accession>
    <name>A0A5C6ZHJ8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Alanine dehydrogenase</fullName>
            <ecNumber evidence="2">1.4.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_10360</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AlaDH/PNT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.1.1" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000286">
        <property type="term" value="F:alanine dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042853">
        <property type="term" value="P:L-alanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05305">
        <property type="entry name" value="L-AlaDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008141">
        <property type="entry name" value="Ala_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008143">
        <property type="entry name" value="Ala_DH/PNT_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007886">
        <property type="entry name" value="AlaDH/PNT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007698">
        <property type="entry name" value="AlaDH/PNT_NAD(H)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42795">
        <property type="entry name" value="PTHR42795"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01262">
        <property type="entry name" value="AlaDh_PNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05222">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01002">
        <property type="entry name" value="AlaDh_PNT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01003">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00837">
        <property type="entry name" value="ALADH_PNT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AlaDh_PNT_N" evidence="6">
        <location>
            <begin position="32"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="AlaDh_PNT_C" evidence="5">
        <location>
            <begin position="177"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD88894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="399" mass="43355" checksum="788D821247E64C97" modified="2019-11-13" version="1">MSEALSPFTKAQLMPQEEMLEVYKKKGDLFIGIPKETYFQEKRVCLTPDAVSALVANGHRVMLEAGAGKGANFKDKTYSDAGAEVTRDTAKVYSCPIILKVEPPSLEEIKMINPQTLLISALQLKTQKKSYFEALASKRITAIAFEYIKDEEGAYPAVRSLSEIAGTASVLIASELLSNVNGGNGLLFGNIPGVPPLEVVIIGAGTVGTFAARSAMGLGANVKVFDNSISRLRRIQSELKQTIYTSTLQPKNLLKALKRCDVVIGAVKGKNRAPIVVSESMVSSMKAGAVVIDVSIDTGGCFETSEMTSHDKPTFEYNNVVHYCVPNIPARYSRSASVSISNIFTPYLLKIAEDGGIENAIRFDRGLKNGLYFYHGVLTNKTVANWFDLDCSDVNLLIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHN5</accession>
    <name>A0A5C6ZHN5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Zinc-dependent metalloprotease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_10590</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04276">
        <property type="entry name" value="ZnMc_MMP_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033413">
        <property type="entry name" value="DUF5117"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033428">
        <property type="entry name" value="DUF5118"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032534">
        <property type="entry name" value="EcxA_zinc-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034032">
        <property type="entry name" value="Zn_MMP-like_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16313">
        <property type="entry name" value="DUF4953"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17148">
        <property type="entry name" value="DUF5117"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17162">
        <property type="entry name" value="DUF5118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5118" evidence="3">
        <location>
            <begin position="48"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5117" evidence="2">
        <location>
            <begin position="108"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4953" evidence="1">
        <location>
            <begin position="431"/>
            <end position="734"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="823" mass="93471" checksum="06BA8B5BB8381061" modified="2019-11-13" version="1">MKNTILVIGLTLSFLAPNLSISQSKRQKKKNKANTEISTPKKDESKIKAYNEVITKAAITDEGLFKVHKVKENYFFEIPDSLLNKDMLLVSRIAKLPANLGGGYINAGSKTGERIIVWQRFEDKILIKERSYNAVADEALPISISVQSNNYEPTLFAFDIEAFSPDSTAVVVDVTKFYNTDVKVISGLSSRLRESYKVKNLDNSRSFINSMKSFPKNIEVVQDMTYTASEPPSAETAETISLQMNQSMVLLPASPMQKRFADERVGWFTFSQVDYGSEQLKADTKTYIRRWRLEPKDPEAYARGELVEPVKPIVYYLDPATPKALRKYIKEGIELWQGPFETAGFKNAIIAKDPPTKEEDPEFSPEDVRYSVIRYVASETRNAVGPSVSDPRSGEIIESDIIWYHNHLRSYRNRYLLETGAANPSARTLNTPAEEIGEMMKMVIAHEVGHALGLPHNMSASKAYDVESYRDGAFTQEFGIAATIMDYARYNYIAQPGDENIRFIRQIGPYDHYAINWGYRRIPNAYTAEAEKPLLNAWILEKEGDPKYVFGKQSSRFDPTSQTEDIGNDAVLASTYALKNLKYVAAHLPQWTSDQTNDYDDLEELYGELLSCYNRYVNHVATNIGGVEEHLLKPNQNGSFYVATPKPVQEQSMQWLQENAFKTPTWLVDKTMLTNIDYAGYTEGLSRLQNRFLNSLLDFETLGRLLDHETINAENYAALEMLEELRKGIWSETTGSSNVDVFRRNLQRAYVERMGYLMTGDLNPKRSNQYFNVAQSDVRALVRGELNQLKSQVASAAARSVNTVTKYHYKDVLKRVELILDPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHP1</accession>
    <name>A0A5C6ZHP1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11245</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="5"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="239"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="265"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="307"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="337"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="370"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="405"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="441" mass="50899" checksum="AB43C713C5464F9C" modified="2019-11-13" version="1">MPKRLVIICLINFLVAALMGLALRYSFIAPIGLNYRFLTHAHSHVAMLGWVYLMLYLLIVHYFIPNELPRCKHTRYQIPKKTNPKFQKKKEKRFKHLGIKPCEINKPVFTRLFWVTQLSVVGMMLSFPVQGYAAISITFSTLHIFCSYYFVYLVWTQQQTKSKATQYLLKAALLFMVISTIGVWCLGPAAAILGQASAFFQIAIQFFLHFQFNGWFLIAVLAVFFHLLEIEYSTAFKRFFVLLISATVLTFALPLQWFAPFEGLLLLNAIGVILQMATLIAFLKLIRPKLYAFFQFKPPVITNLYRFALICVILKIVLPVITLLPSFANVLFSHRNFIIGFIHLVMLGIISSFLLAFISQMYFRKMGKTLNFGIYSFLLGIFLTEILLAIQGYQFYFGKGILLNYYAFLFSFSILLPLGLFLFIYKFISSKTHERQTSKTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHX5</accession>
    <name>A0A5C6ZHX5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Nucleotidyl transferase AbiEii/AbiGii toxin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_12375</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014942">
        <property type="entry name" value="AbiEii"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08843">
        <property type="entry name" value="AbiEii"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="267" mass="31616" checksum="0C1D022525852B24" modified="2019-11-13" version="1">MIKPAEIQNKARAVGVRDQQIEKDYMLSWILQGIAQHSTLSKTIVFKGGTVLKKVYFKDYRFSEDLDFSLLDDTISNEQIFEWFTEVFEYIKEEANIPLEIIDNDEHQDGGINFYISYVDPLGGLGANKKVKVDISRSEKLVFEPVLNDAFIDYTDQEEHQLLCYSLEEVLVEKLRSVMQRMQARDFYDIWYLLEIHNMDIDFHIAEFRQKCESKDIDPTDFHTKLEQRLPQYKGRWEKSLADQIQDLPDFETVLREVMRHLKKLEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHZ9</accession>
    <name>A0A5C6ZHZ9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_09850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="335"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="391"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="429" mass="49723" checksum="A91896D19A9BFEF9" modified="2019-11-13" version="1">MTEALLIILFFFFLYRLIKNIGKSFPLFDLVIVLYLLQYGIAPLLEYNIDPLNSMSISKEEYISFATFSCLAFIIGLFSVKNKFKKLEITVSSELASNLGRAFLLIALFGNLAVFFLPYSLRAILTFFVILKSPGVFCLIYSDKKLDKIIIALIFLQTAISSILNAMLIEFIVFTVFFAMFYSLRYEVSTKLKYTIIAIGILFLSVYQGVKQEYRENTWEEEIGWQGKVAILTDLISIDSFTAAFDSDLDNNESIVQTVHRLNQGWQTSMVVNHVPKYVDFENGSALKDDILSSIMPRFLMPNKRVVNDYERYNHYTGYILNDQTSMSVGVIGDFYLNFGFNGTLVSMFVFGFFMAKVCLWFYKKYIVKNPIDLVWLPFIFSYFIRPGNEFYMVLNHLIKAFIIFFLVRKFLYPYIYKRLALKSSRLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ79</accession>
    <name>A0A5C6ZJ79_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Helix-turn-helix transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_07485</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="2">
        <location>
            <begin position="197"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="297" mass="34041" checksum="340E2CC5AE5F816A" modified="2019-11-13" version="1">MALSSLENTARGSFKETKVEDGFFVLTFQNEEDHLQTLERDIDNNFIQFHYCIKGSSEFVFNNGAYRLQIAEENSLLLYNPQRDLPIHLDVNPKSWLVSILVSIKKFHGLFSQEADYITFLSEDNKDKKYYKDGKISPSMAIALNQLINYNLNASIKTLYFKGKALELLSLYFNRSEEADIEQCPFLEDETNVIKIRKAKDIIIARMAEPPTLQELSEEIGLSLKKLKEGFKQIYGDTVYSFLFDYKMEVARKLLEAGNHNVNEVGLKVGYSASSHFIAAFKKKYGTTPKKYLMALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ85</accession>
    <name>A0A5C6ZJ85_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Insulinase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_08200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="SSF63411"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023099377" evidence="1">
        <location>
            <begin position="21"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16" evidence="2">
        <location>
            <begin position="36"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_C" evidence="3">
        <location>
            <begin position="191"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="440" mass="50193" checksum="8A753D98C0E41804" modified="2019-11-13" version="1">MKKCLFILAVMGLVGFSSNAQQVEFEQFDLDNGMHVILHQDNTAPVVTVSVMYHVGAKDENPERTGFAHFFEHLLFEGTKNIGRGEWFTIVSSNGGTNNANTTDDRTYYYEVFPSNNVELGLWMESERLMHPIINQIGVDTQNEVVKEEKRLRVDNSPYGKFLENIKLNMFEKHPYKGTTIGKMEHLDAATLEEFQAFYEKYYVPNNAVLVVAGDINKSEVKKMVKDYFGPIPRGADIVRSFPKEDPITEPMTATAYDSNIQIPAIMAAYRTPSFKDRDAYVLAMISSYLSGGKSSKLYKKIVDEKKMALQVGALDFSQEDYGTYILYGLPLGDTKLEDLVTEIDEEIVKLQTELISERDYEKLQNVFENQFVNSNSSVTGIANSLARYYMLYGDVNLINNEIDIYRSITRAEIQEVANKYLNPNQRLLLEYLPEDKQEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJF9</accession>
    <name>A0A5C6ZJF9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Non-homologous end joining protein Ku</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">ku</name>
        <name evidence="4" type="ORF">ESY86_06930</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer. Interacts with LigD.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the prokaryotic Ku family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006303">
        <property type="term" value="P:double-strand break repair via nonhomologous end joining"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01875">
        <property type="entry name" value="Prokaryotic_Ku"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006164">
        <property type="entry name" value="Ku70/Ku80_beta-barrel_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009187">
        <property type="entry name" value="Prok_Ku"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016194">
        <property type="entry name" value="SPOC-like_C_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41251">
        <property type="entry name" value="PTHR41251"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02735">
        <property type="entry name" value="Ku"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006493">
        <property type="entry name" value="Prok_Ku"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00559">
        <property type="entry name" value="Ku78"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100939">
        <property type="entry name" value="SSF100939"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02772">
        <property type="entry name" value="Ku_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0227">DNA damage</keyword>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="2" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ku" evidence="3">
        <location>
            <begin position="52"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="257" mass="29833" checksum="A4AA3A5644200822" modified="2019-11-13" version="1">MKSVWNGSISFGLISIPIKMYSATESRRLDLDMLDKHDHARIRYKRVNEDTGKEVEWKDIVKGFKKDESYVILEKEDFENANNKKSKTIDIEEFVEETEVADMLFKKPYYLEAQKEGTKAYNLLRDALKKTGKLGVATFVMRQKENLALIGVYKNVIVLHVIRFAEEIRDAKEIKLSKTKTSDKEIKMAESLIENYTEKFDFKKYKDIYNKQLMKIIESKSTGKTVKVKQEKAEPTAAKDLMAKLKASLEQHKKKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJG2</accession>
    <name>A0A5C6ZJG2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">SDR family oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_05940</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="260" mass="27849" checksum="D0DE11773750C608" modified="2019-11-13" version="1">MDLQLNNKYALVCGSTSGIGKATAMALAAEGVQVTLVARNEDKLKATLNELPKQRNHDYIVADFSNPQHLKTEVEAYINKHHGFHILVNNTGGPAGGPIFSAEVEEFEAAFTQHLKCNHILAQAIVPFMKRECFGRIINVISTSVKQPLDGLGVSNTIRGAVANWSKTLANELGQFGITVNNVLPGATGTGRLSQIIKNKSDKTGKTEEEAANAMKNAVPAKRFAKPEELADAITFLASARAGYINGINLPVDGGRTKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJR4</accession>
    <name>A0A5C6ZJR4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_07230</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="180" mass="20842" checksum="9FC059CA00FDC6ED" modified="2019-11-13" version="1">MRLKTLFYISLTVFLFNCQEAKVSQEKKETQAEIEARTIGPKDIEALEYTEFSLSQDAKKTVTDWQKYKDLNVQVLLLKSADFSFFNDDRTNVLTFIKDLKAEMPKAIRTKPIEARFSALDTKLQKLNSTLLLYNSTKAEKLESVKEFLISVSNFNLQINKKLEFEKNNIGRPDMNPSQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJS3</accession>
    <name>A0A5C6ZJS3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Acyl-ACP desaturase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_07280</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="7">Binds 2 iron ions per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the fatty acid desaturase type 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045300">
        <property type="term" value="F:acyl-[acyl-carrier-protein] desaturase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01050">
        <property type="entry name" value="Acyl_ACP_Desat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.620.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005067">
        <property type="entry name" value="Fatty_acid_desaturase-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012348">
        <property type="entry name" value="RNR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31155">
        <property type="entry name" value="PTHR31155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03405">
        <property type="entry name" value="FA_desaturase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000346">
        <property type="entry name" value="Dlt9_acylACP_des"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="7">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="197"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="200"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000346-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD89581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="329" mass="38880" checksum="276611A0A91D24E8" modified="2019-11-13" version="1">MSLKNIRLEVMQHLEKDVESLIQKYLIPTEKIWQPSDFLPNSESENFYEEVREIRELSKDLPYDFWVVLVGDMITEEALPTYESWLMDVEGVGQVEHNSWSKWVRHWTSEENRHGDVLNKYLYLSGRVNMREIEMTTQHLIADGFDIGTDRDPYKNFVYTSFQELATYVSHNRVAKMAKEKGNKQLAKMCKIISGDEMRHHHAYSEFVERIFVEDPSQMMMAFHYMMKQKITMPAHFLRESGDKIGTAFEEFSNTAQRIGVYTSADYVEILQKLIDRWDIGNIKGLSDEAEKAREYLMKLPSRMIRLSERMKIPENSYEFKWVQPAVSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJT4</accession>
    <name>A0A5C6ZJT4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FUSC-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_04825</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032692">
        <property type="entry name" value="YccS_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12805">
        <property type="entry name" value="FUSC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="452"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="490"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="520"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="domain" description="FUSC-like" evidence="2">
        <location>
            <begin position="72"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="738" mass="84247" checksum="FC7E6E049E222259" modified="2019-11-13" version="1">MLKNAFKELVNFFKSTNFSKAILIGIAISVPIVLGLSFDRFEIGLAVCFGAFWCSPSDVHGSLKHKTIGILYSAALVMLVSFIAGYLHLLSYFLIVVLGLLTFGIAYISVYGFRASLISFSGLLALVLSFAHQVQELEIYEYSLLIGLGGLWYLLLSVIWYHLNPRAQTEEVLAEIFERTANFLVIRGKLIGPQENRKDLLTELLTLQNELIEKHATMRDILMATRINSGKSNYEGKQLLIFVQLVELLETAIANPVNYVKMDALLTKHPEYIKKFQSLIFELAIQLTEISRHKKNPKKLPEHTNIVSLFLEAETQIKHYKKELNPSDYDGYLMMRNLLAYQEQQFERIKRIKWLLSDPDLSTTEFITRDSLRRFIVSQDYDPKLLLRNFSFKSTIFKHCLRLAATMMIGYGIGKYFDFQNPYWILLTIIVIMRPSYGLTKTRSKDRILGTLIGGAIATGLVFVVQNPYVYGVLGISSLVIAFSMLQKNYKASATFITLSVIFIYAIIRPDVLNVIQYRIIDTLIGATLSFLAMLWLWPAWGFMDIGDNIKNSLKANREFFKNISEFYKQKGQIPTAFKVSRKEAFVQTSNLSAAFQRMAQEPESKQKSLNQYYELVVLNHNFLSSLASLSTYLQHHKTTEASAEFSEVAEVILNNLDTILKNLDLNKEPRELSSEVPATPTFDSSIEIASERIKKEAFANLPHLQQHQEAHLIWEQMNWLLTMSDKLLRLSAGLDLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJX9</accession>
    <name>A0A5C6ZJX9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">UDP-N-acetylenolpyruvoylglucosamine reductase</fullName>
            <ecNumber evidence="16">1.3.1.98</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">UDP-N-acetylmuramate dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16 18" type="primary">murB</name>
        <name evidence="18" type="ORF">ESY86_05890</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 16">Cell wall formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 16">
            <text>NADP(+) + UDP-N-acetyl-alpha-D-muramate = H(+) + NADPH + UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine</text>
            <dbReference type="Rhea" id="RHEA:12248"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:68483"/>
            <dbReference type="ChEBI" id="CHEBI:70757"/>
            <dbReference type="EC" id="1.3.1.98"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 16">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5 16">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 16">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="16">Belongs to the MurB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.98" evidence="16"/>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008762">
        <property type="term" value="F:UDP-N-acetylmuramate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.78.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00037">
        <property type="entry name" value="MurB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003170">
        <property type="entry name" value="MurB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011601">
        <property type="entry name" value="MurB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036635">
        <property type="entry name" value="MurB_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21071">
        <property type="entry name" value="PTHR21071"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02873">
        <property type="entry name" value="MurB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56194">
        <property type="entry name" value="SSF56194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00179">
        <property type="entry name" value="murB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14 16" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7 16" id="KW-0132">Cell division</keyword>
    <keyword evidence="11 16" id="KW-0133">Cell shape</keyword>
    <keyword evidence="15 16" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6 16" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 16" id="KW-0274">FAD</keyword>
    <keyword evidence="8 16" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10 16" id="KW-0521">NADP</keyword>
    <keyword evidence="13 16 18" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12 16" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="17">
        <location>
            <begin position="17"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="active site" evidence="16">
        <location>
            <position position="162"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="16">
        <location>
            <position position="237"/>
        </location>
    </feature>
    <feature type="active site" evidence="16">
        <location>
            <position position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="TXD90266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="337" mass="37168" checksum="3E56AF15BEFAC666" modified="2019-11-13" version="1">MHIETNISLKTLNTFGIDVKAKHFVSIHSVSDLQTLLRKKEYPKKLILGGGSNMLLTKDVDALVILIDIKGIEVIKETPKGVWVKVCAGENWHDFVLYTIDHDFGGLENLSLIPGNVGTAPIQNIGAYGVELKDTFRSCDAVHVETGKVKTFYKEDCDFGYRDSVFKSQLKGQYIITSVVFELSKEAHVLKTTYGAISSQLEQRQISNPSLKDVSEAVIAIRQSKLPDPKKIGNSGSFFKNPIISIAQLEKLRKSFEGMPSYPISDTEVKVPAGWLIEHAGFKGKTFGNYGVHKNQALVLVNYGGATGLEILGLARLIQNTISRLYGIDIEAEVNVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJZ2</accession>
    <name>A0A5C6ZJZ2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Fe-S cluster assembly ATPase SufC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">sufC</name>
        <name evidence="6" type="ORF">ESY86_08300</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily. Ycf16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03217">
        <property type="entry name" value="ABC_FeS_Assembly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010230">
        <property type="entry name" value="FeS-cluster_ATPase_SufC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43204">
        <property type="entry name" value="PTHR43204"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01978">
        <property type="entry name" value="sufC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="2"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD89380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="251" mass="27926" checksum="C53B8B157A54BE5A" modified="2019-11-13" version="1">MLKIIDLHASVEGKEILRGINLEVKAGEVHAIMGPNGSGKSTLANVIAGKEEYEVEKGQILLEGEDIDELSADERAHKGVFLSFQYPIEIPGVSVTNFIKTAINANRKANGLDDMPAKDMLKMIREKSEMLAIDRKFLSRSLNEGFSGGEKKRNEIFQMAMLEPKLAILDETDSGLDIDALRIVADGVNALKTKDNAVIVITHYQRLLDHIIPDFVHVLHEGRIVKSGSKELAHKLEEKGYDWIKEEVELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK09</accession>
    <name>A0A5C6ZK09_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF998 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009339">
        <property type="entry name" value="DUF998"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06197">
        <property type="entry name" value="DUF998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="206" mass="22675" checksum="B9D8EBB7CD76C528" modified="2019-11-13" version="1">MIHKHEIIKYGGIALIAGSILALVADVVGILVVEDHNPIRQTVSQLAHGKYAYIQDIGLALFGVGILIAGATLYLWKSDAFKCEWGATLLSIMGICIVVLAEFNEFAGTPGTTVHIVLAVFIGVLFMLCTFLIGLAFKKINKNWYYASIGMGILFLVSCSGFLVISQAYQGAYERGVIQIVLIWFCAMGYQMIKYPEKTMDFETFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK22</accession>
    <name>A0A5C6ZK22_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">YtxH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024623">
        <property type="entry name" value="YtxH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12732">
        <property type="entry name" value="YtxH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="105" mass="11453" checksum="167639CA3DDA3699" modified="2019-11-13" version="1">MENNNGNLLISFLTGAVIGAAVGILYAPYKGSKTRGKIKHGVTDTAHDISERLKHAKNDLSKSAHDQKKAFDKKLEATISKMNYKAEDLISALEGKLEDLKNKNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK42</accession>
    <name>A0A5C6ZK42_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Nicotinamide mononucleotide transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_08530</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nicotinamide ribonucleoside (NR) uptake permease (TC 4.B.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034257">
        <property type="term" value="F:nicotinamide riboside transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006419">
        <property type="entry name" value="NMN_transpt_PnuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36122">
        <property type="entry name" value="PTHR36122"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04973">
        <property type="entry name" value="NMN_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01528">
        <property type="entry name" value="NMN_trans_PnuC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="65"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="156"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="178"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD89508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="208" mass="24283" checksum="FA04735EEB6061A3" modified="2019-11-13" version="1">MFEFFLEPYRSASTLDIVLEILAFVFGIASVVYAKQENILVYPTGLVATVITVYLLYKAGYLGDMMMNFYYSVMSIYGWWNWSRKKKGGFVLPISRTTTRQKWIGIVLFVLTMMVTYLVYRVYDYELQIPNYIDIFTSGLFFTAMWYMATKKLENWTLWIIGDLITIPLYAYRGLGILSLQYLIFTILAIQGYIAWRNSLDKTTSQIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK67</accession>
    <name>A0A5C6ZK67_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_07075</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="65" mass="7218" checksum="10E9695F45EEA4DA" modified="2019-11-13" version="1">MGIVDFKHKSISEKIDNKMVFESVELENHLLACSLSKATNGPRLYGGIGTEIKTILKGIEQELDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK85</accession>
    <name>A0A5C6ZK85_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cell shape-determining protein MreC</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Cell shape protein MreC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">mreC</name>
        <name evidence="5" type="ORF">ESY86_05795</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MreC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042177">
        <property type="entry name" value="Cell/Rod_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042175">
        <property type="entry name" value="Cell/Rod_MreC_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007221">
        <property type="entry name" value="MreC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34138">
        <property type="entry name" value="PTHR34138"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04085">
        <property type="entry name" value="MreC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0133">Cell shape</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00032089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="275" mass="30797" checksum="15C2BD52422F7EDA" modified="2019-11-13" version="1">MQQIINFVIRNKNFLLFLLLFGISLGLTIQSHSYHRSKFINSANFFTGGIYERANEVTTYFTLKEQNQQLFEENRRLRSQIFNPSDSLQKEPITLDTSSTGALYRFNKAKVINNNYSLSKNYLTLNIGKNDSITEDMGVITSKGIVGIIDNTSANYSRVLSILNSRSRINAQLKQSNHIGSLRWDAKSSEIVQLVDVSKFAPVKVGDTITTGGQSAIFPKGIPIGSIVSFDIDPGGDTYTISVKLFNDMTSLYHVYIIKNKDASEIKALENQLSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKL4</accession>
    <name>A0A5C6ZKL4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AAA family ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03365</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027785">
        <property type="entry name" value="UvrD-like_helicase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13538">
        <property type="entry name" value="UvrD_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD_C_2" evidence="1">
        <location>
            <begin position="415"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="474" mass="54694" checksum="E79118486F3D918A" modified="2019-11-13" version="1">MTASDFYRLLKRKFPFEPTSKQNIVLDQLSKFVFDDAKDELYLLKGYAGTGKTSIVGTLVSHLWEAKKSAVLMAPTGRAAKVISNYSKKEAFTIHKKIYFPKKNKTGGVKFVIQPNKHRNTIFIVDEASMISDSTSDGQDHESTSLLDDLMQYVYSGHNCKLLLIGDKAQLPPVKSDLSPALDAQILELHYNKRLITVELDEVVRQELDSGILENATRLREVLQNEFFESFQFNIKSFPDVIRLIDGYEIMDAINDSYSENGHEETAVIVRSNKRANLYNQNIRTRILFNENELSVGDFLMVVRNNYFWIKPTTDAGFIANGDIVQVLEMFSVKELYGFRFAEVKIQMVDYPNMAPFETVLLLDTLEAETPSLTYEDSNRLYQEVQKDYQDETSNYKKFLKTKNNHFFNALQVKFAYAITCHKSQGGQWNTIFVEQPYLPNGIDRDYVRWLYTAITRAKDKLYLIGFKDDFFEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKM9</accession>
    <name>A0A5C6ZKM9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05255</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="147" mass="16773" checksum="6FCBD320C40706FA" modified="2019-11-13" version="1">MQKHNHIKALFFLGIFGLMLLHQVVPHLHHQHDVEHSHKAVSNSNSDSHSHHHDVPEKESSNKGLLDLFLEVHIHSVVANEIVVTHNSSVKQLKLKKDVKTSIFLNRYSISINYDDEAEKLTVYHPPNIYCHQYLSSLDTRGPPSLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKP2</accession>
    <name>A0A5C6ZKP2_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Acetolactate synthase small subunit</fullName>
            <shortName evidence="8">AHAS</shortName>
            <shortName evidence="8">ALS</shortName>
            <ecNumber evidence="8">2.2.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Acetohydroxy-acid synthase small subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ilvN</name>
        <name evidence="10" type="ORF">ESY86_02280</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>H(+) + 2 pyruvate = (2S)-2-acetolactate + CO2</text>
            <dbReference type="Rhea" id="RHEA:25249"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58476"/>
            <dbReference type="EC" id="2.2.1.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 8">Dimer of large and small chains.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the acetolactate synthase small subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.6" evidence="8"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00055"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00059"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003984">
        <property type="term" value="F:acetolactate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990610">
        <property type="term" value="F:acetolactate synthase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04878">
        <property type="entry name" value="ACT_AHAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004789">
        <property type="entry name" value="Acetalactate_synth_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027271">
        <property type="entry name" value="Acetolactate_synth/TF_NikR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019455">
        <property type="entry name" value="Acetolactate_synth_ssu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039557">
        <property type="entry name" value="AHAS_ACT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30239">
        <property type="entry name" value="PTHR30239"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01842">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10369">
        <property type="entry name" value="ALS_ss_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00119">
        <property type="entry name" value="acolac_sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACT" evidence="9">
        <location>
            <begin position="8"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU368092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD90807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="177" mass="20865" checksum="3759DC34B128E36B" modified="2019-11-13" version="1">MNDNIQYTVFIYTENNIGLLNRISAIFQRRHINIESINSSASEIENVSKWTIVVELSEERIKKIIGQLEKQVEVIKAFYHTEDDIIYQESSIFKMRSALLFEERQIQNIIKESNARIVTVNREFFVIEKSGRKEEIDMLSRELSVFGIMQYTRSGRIAVTKDEMRISTMLREAFLHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKQ3</accession>
    <name>A0A5C6ZKQ3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">YegS/Rv2252/BmrU family lipid kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003951">
        <property type="term" value="F:NAD+ kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005218">
        <property type="entry name" value="Diacylglycerol/lipid_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001206">
        <property type="entry name" value="Diacylglycerol_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045540">
        <property type="entry name" value="YegS/DAGK_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00781">
        <property type="entry name" value="DAGK_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19279">
        <property type="entry name" value="YegS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00046">
        <property type="entry name" value="DAGKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="SSF111331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00147">
        <property type="entry name" value="TIGR00147"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50146">
        <property type="entry name" value="DAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAGKc" evidence="1">
        <location>
            <begin position="2"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="294" mass="31682" checksum="A1B8A64FACDF997E" modified="2019-11-13" version="1">MSAKSNILLVVNPKAGSMDVDLVRSKMSEITSKQKLSFETFETTGNNDKEQLSKKVEHSQFSRVIAAGGDGTINLVASVIVNTEVSLGILACGSANGLARNLDIPNDLEQQIHKAIAINTTKMDVLMVNGVLCMHIAGLGLNAELIRNYSNSKIRGKLGYALGSIPTLLKSDYPYNFEIVINGKSENHQGVLLAIANAADYGTGATINANAILNDGKFEVVLFKAFNLYQIFKTFSSNPKIESEHAETYSVTTVQINCSKAMALQVDGEFIGETTTVKAHILHRALKLASMDTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKS4</accession>
    <name>A0A5C6ZKS4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FtsQ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_09400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005548">
        <property type="entry name" value="Cell_div_FtsQ/DivIB_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03799">
        <property type="entry name" value="FtsQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FtsQ" evidence="1">
        <location>
            <begin position="112"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="239" mass="27113" checksum="9CB52D4FFB46D013" modified="2019-11-13" version="1">MRINYNYIKVGALLLLVVFLCAFSYERNSARKVSDPEIKFIGDDNLFVTHTTVSKLLIVNNASVANTPKEIIDLNLLEVALNSNEMIKNAQVFMNVDGLITAEIEQKKPIARISTNASYYIDDEGNYMPLSSNYTARVPLVTGFIEKNKLSAVYEVAMKVQSDAFLTRNVVEIHQNQNGTIDLKFRGHDFTIHLGRTNLMDKKINNLKAFYKKAMKDSMLDAYSLINLKFDKQVICTKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKX6</accession>
    <name>A0A5C6ZKX6_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cysteine--tRNA ligase</fullName>
            <ecNumber evidence="11">6.1.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Cysteinyl-tRNA synthetase</fullName>
            <shortName evidence="11">CysRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">cysS</name>
        <name evidence="13" type="ORF">ESY86_04585</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + L-cysteine + tRNA(Cys) = AMP + diphosphate + L-cysteinyl-tRNA(Cys)</text>
            <dbReference type="Rhea" id="RHEA:17773"/>
            <dbReference type="Rhea" id="RHEA-COMP:9661"/>
            <dbReference type="Rhea" id="RHEA-COMP:9679"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78517"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 11">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.16" evidence="11"/>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004817">
        <property type="term" value="F:cysteine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006423">
        <property type="term" value="P:cysteinyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00672">
        <property type="entry name" value="CysRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00041">
        <property type="entry name" value="Cys_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015803">
        <property type="entry name" value="Cys-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015273">
        <property type="entry name" value="Cys-tRNA-synt_Ia_DALR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024909">
        <property type="entry name" value="Cys-tRNA/MSH_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032678">
        <property type="entry name" value="tRNA-synt_1_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10890">
        <property type="entry name" value="PTHR10890"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09190">
        <property type="entry name" value="DALR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01406">
        <property type="entry name" value="tRNA-synt_1e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00983">
        <property type="entry name" value="TRNASYNTHCYS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00840">
        <property type="entry name" value="DALR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00435">
        <property type="entry name" value="cysS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 11 13" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="DALR_2" evidence="12">
        <location>
            <begin position="374"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="11">
        <location>
            <begin position="37"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="230"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="255"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="290"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TXD90037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="493" mass="55752" checksum="C3E6494CD8C7E35B" modified="2019-11-13" version="1">MSLHKEQQIKIYNTLSGKKETFTPIEPGHIGMYVCGPTVYSNVHLGNVRTFMSFDMVFRYFKHLGYKVRYVRNITDAGHLENDADAGEDKITKKARLESIEPMEVVQRYTVDFHNTLNTFNFLPPSIEPTATGHIIEQIELVKKIIANGFGYEVNGSVYFDVHKFNESYTYGILSKRKLEDLIHNTRALDGQSDKKNPQDFALWKKAEPQHIMRWPSPWSDGFPGWHLECTTMSTKYLGEHFDIHGGGMDLKFPHHECEIAQNEAAVGRSPVNFWMHANMLELNGQRMSKTTGNIINPAELLSGKNDIMSKAYSPSVIRFFIAQSSYRSILDLTNDGLLSSEKGFLRLMDAINALDELKAGTASTFDIAEWQQRCYDAMNDDFNSPILIANLFEAVKYINQLKEGTATLTAEDLELLKSSMHSFCFDILGLENVGITDSSSEKLAGAVELLIELRQQARANKDFALSDKIRDQLAEKGIQLNDSKEGTTFDVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKY3</accession>
    <name>A0A5C6ZKY3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">T9SS type A sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_03815</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00063">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007346">
        <property type="entry name" value="Endonuclease-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003961">
        <property type="entry name" value="FN3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036116">
        <property type="entry name" value="FN3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044925">
        <property type="entry name" value="His-Me_finger_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33607">
        <property type="entry name" value="PTHR33607"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04231">
        <property type="entry name" value="Endonuclease_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00041">
        <property type="entry name" value="fn3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00060">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49265">
        <property type="entry name" value="SSF49265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54060">
        <property type="entry name" value="SSF54060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50853">
        <property type="entry name" value="FN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022704017" evidence="1">
        <location>
            <begin position="19"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="domain" description="Fibronectin type-III" evidence="2">
        <location>
            <begin position="296"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="607" mass="66575" checksum="504FAF15899D006D" modified="2019-11-13" version="1">MKQFYLFTFLVLTLNASAQIPAGYYDSASGTSYELKTQLYNIIDDHNVQSYGAMYTFIATYDRDNYYETNGANTILDVYSENPATSPNNNDPYNFTPTVNQCGNYSDEGDCYNREHVVPQSVFNSEFPMYSDAHELLPTDGRVNGLRSSYPFGVVDDSQLVSQNNTANPTLNGSKLGNNFNGGYSSGYTGIVFEPIDEFKGDIARIHFYFITRYQNLVGNWSSYEMFDGSTDQVLDDPFLSIMLNWHQNDPVSQKEIDRNNNIFYNHQQNRNPFVDHPEFVAEIWTVEPDTEAPTTPTSLMASNPTDNSISLSWTASTDDTAVTAYEIFRNGASAYTTTETTYVANNLTANTNYCFTVRALDAATNASDLSNEACDTTTNNGTTSTDCLAETFANITTGQNGYAERTWTGDDGGIWSATDARTDQILNNEAITIRDGVLSMPATSGGIGALTVTTQRIFSGSNGTFNINVGGTLVATIPYGASVETVTIQNINIPGNVTVTIDGNSATSNRVVFDDLSYTCYADLSLADFDASAVAVYPNPVENTLMIALKNPAETTVEIFDILGKKVLSKAIEQTKALNVSHLNSGIYILRITQNNTSITKKLIKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL91</accession>
    <name>A0A5C6ZL91_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dihydropteroate synthase</fullName>
            <shortName evidence="1">DHPS</shortName>
            <ecNumber evidence="1">2.5.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Dihydropteroate pyrophosphorylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">folP</name>
        <name evidence="3" type="ORF">ESY86_04265</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 7,8-dihydrofolate from 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate and 4-aminobenzoate: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DHPS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.15" evidence="1"/>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00156"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004156">
        <property type="term" value="F:dihydropteroate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00739">
        <property type="entry name" value="DHPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045031">
        <property type="entry name" value="DHP_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006390">
        <property type="entry name" value="DHP_synth_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011005">
        <property type="entry name" value="Dihydropteroate_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000489">
        <property type="entry name" value="Pterin-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20941">
        <property type="entry name" value="PTHR20941"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00809">
        <property type="entry name" value="Pterin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51717">
        <property type="entry name" value="SSF51717"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01496">
        <property type="entry name" value="DHPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00792">
        <property type="entry name" value="DHPS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50972">
        <property type="entry name" value="PTERIN_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pterin-binding" evidence="2">
        <location>
            <begin position="15"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU361205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="274" mass="30484" checksum="07018BB282C77736" modified="2019-11-13" version="1">MTINCKGQLIDLTTPKVMGILNVTPDSFYDGGRFKSEKAILDQVTLMLKEGATFIDIGAQSSKPDAETVSEAEELQRLLPVLELLQQQFPEILMSVDTFRSEVAKQAVHAGACMINDISAGHLDAQMLETIAKLKVPYIMMHMRGTPKTMKNLTDYEDLIKEIVFYFSERIAKARHLGISDLILDPGFGFAKTLEQNFELLNKLELLKMAELPVLVGVSRKSMIYKSLNTTAEKALNGTSILNTIALQKGAKILRVHDVKEAMECVHLVKLLNC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLF0</accession>
    <name>A0A5C6ZLF0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Formimidoylglutamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the arginase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016813">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006035">
        <property type="entry name" value="Ureohydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023696">
        <property type="entry name" value="Ureohydrolase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11358">
        <property type="entry name" value="PTHR11358"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00491">
        <property type="entry name" value="Arginase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52768">
        <property type="entry name" value="SSF52768"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51409">
        <property type="entry name" value="ARGINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="388" mass="44170" checksum="C5485A419F443AF3" modified="2019-11-13" version="1">MNFNFLSPVSEEVLSHNATLSAQALGKKIRIHSKTEGIPELDGVQLAIIGVLEHRNDVNYTGQSFGLETIRTSLYSLFPGNWNTTMADLGDILPGDSVEDTYYALKTTISLLIEKKIIPIILGGSQDLTYANYRAYDTMAPMVNIVNVDSNFDLGDVSIEMKNNSFLGKIILEQPYNLFNYSAIGYQTYFNSQEEIDLMEKLYFEAYRLGEVSNKLNLVEPVMRDAHIVSIDLKSVRASELGDNQKYSPNGFDGKEICAIARYAGISNKVSSFGIYEFKPTKALDTTPMLISQMIWYFIEGVNCRVNDDDFAKEDQHQKFNVLIDDDELIFYKSIKSGRWWIEIPFLPNVNNKLKKHALLPCTHEDYMEASHGKIPERWYKAYKKNSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLH7</accession>
    <name>A0A5C6ZLH7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_02660</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="62" mass="7457" checksum="644DFB927D3ACC38" modified="2019-11-13" version="1">MKIVQKEEDNFSNSIRSFDWYQSYTGGVNFETEIYCIEPNHYITKPKWKTCEICSATIRERQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLJ6</accession>
    <name>A0A5C6ZLJ6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SusF/SusE family outer membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_02835</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001070">
        <property type="term" value="F:starch binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025970">
        <property type="entry name" value="SusE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032187">
        <property type="entry name" value="SusF/SusE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14292">
        <property type="entry name" value="SusE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16411">
        <property type="entry name" value="SusF_SusE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SusE" evidence="2">
        <location>
            <begin position="25"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="377" mass="40620" checksum="30BF75471BBCD988" modified="2019-11-13" version="1">MKIRTYIKFLPFVISMIFLTTSCEDDASEFVASESTPIVLEELPISEIAIDGSNPSNPAVTFNWSNADYSQAVVENYALEFSSDQSFTNPVQVASSVGVSSASLTMSDLNGRVSAAGLPPLLMNPVYARVISSIGVQAELQSVSNIISFNATPYFNYDFSDFYLVGNGTLADWNNNNNNPPLFRDPNDSDFYTYTGFFTKGGGGFDDGRFKILETRGMWQPQWGNAASEGSDNVSGTGEVAGNPGTQSSDPGRFGVPSDGYFTFTIDFDELTYTIDSYDATGAVDFTDVTVQGSALSDDTAMQQTAFDPHLWYINNVALQSGDLQIVTNTGAAWGGSSAFSGVATEGGSSIPVLVQANYEIWFNDLTGDYIMIPLNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLY4</accession>
    <name>A0A5C6ZLY4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Kynureninase</fullName>
            <ecNumber evidence="4 5">3.7.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">L-kynurenine hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4 7" type="primary">kynU</name>
        <name evidence="7" type="ORF">ESY86_05920</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3-hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3-hydroxyanthranilic acid (3-OHAA), respectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>3-hydroxy-L-kynurenine + H2O = 3-hydroxyanthranilate + H(+) + L-alanine</text>
            <dbReference type="Rhea" id="RHEA:25143"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:36559"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:58125"/>
            <dbReference type="EC" id="3.7.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 5">
            <text>H2O + L-kynurenine = anthranilate + H(+) + L-alanine</text>
            <dbReference type="Rhea" id="RHEA:16813"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16567"/>
            <dbReference type="ChEBI" id="CHEBI:57959"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="EC" id="3.7.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4 5">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 5">Amino-acid degradation; L-kynurenine degradation; L-alanine and anthranilate from L-kynurenine: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 5">Cofactor biosynthesis; NAD(+) biosynthesis; quinolinate from L-kynurenine: step 2/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the kynureninase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.7.1.3" evidence="4 5"/>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00329"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00334">
        <property type="reaction ID" value="UER00455"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061981">
        <property type="term" value="F:3-hydroxykynureninase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030429">
        <property type="term" value="F:kynureninase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034354">
        <property type="term" value="P:'de novo' NAD biosynthetic process from tryptophan"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043420">
        <property type="term" value="P:anthranilate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097053">
        <property type="term" value="P:L-kynurenine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019805">
        <property type="term" value="P:quinolinate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006569">
        <property type="term" value="P:tryptophan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01970">
        <property type="entry name" value="Kynureninase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010111">
        <property type="entry name" value="Kynureninase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14084">
        <property type="entry name" value="PTHR14084"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038800">
        <property type="entry name" value="KYNU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01814">
        <property type="entry name" value="kynureninase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 4 5" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="3 4 5" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotran_5" evidence="6">
        <location>
            <begin position="53"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="4">
        <location>
            <begin position="135"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="223"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="276"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="4">
        <location>
            <position position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR038800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD90271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="421" mass="47833" checksum="4762243BAC11FE42" modified="2019-11-13" version="1">MSNYKLGLDFAKAQDRNDPLGHFRDQFHIPKDKNGKALIYMTGNSLGLQPKITKDYIHQELEDWANLGVEGHTDGKHPWLNYHELLTETMAHIVGAKPIETIVMNSLTVNLHLMMVSFYQPTKKRYKILIEADAFPSDKYAVQSQLRHHGFDDQEGLIQWKAPEGEELANYEDLETLLKTHGDEIALVMIGGVNYYTGQFFDLKRIAKLAHAYGCMVGFDCAHGAGNVKLNLHDSGADFAVWCSYKYLNSGPGSLAGAFIHERHAHKKELNRFTGWWSHNKEKRFKMRDDFDQLTGAEGWQLSNPTILSMAAIRASLDVFKDAGFDRLCEKSNELTGYFEFLINELNNSELKIITPSDPNARGCQLSIQVKNANKNLHKKLTEAGVISDWREPDVIRCAPTPLYNSFEDVFNLVERLKNII</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLZ2</accession>
    <name>A0A5C6ZLZ2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type IX secretion system membrane protein PorP/SprF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019861">
        <property type="entry name" value="PorP/SprF_Bacteroidetes"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11751">
        <property type="entry name" value="PorP_SprF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03519">
        <property type="entry name" value="T9SS_PorP_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023128050" evidence="1">
        <location>
            <begin position="22"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="305" mass="34597" checksum="912A01507E2EBE9A" modified="2019-11-13" version="1">MKFLKYSIIAFMLLSGLMSVAQQLPQFTQYMYNTIAINPAYAGSRETLSVVGLHRSQWVGLQGGPTTQTLSVHAPLRNEKVGLGVSFINDQLGYQNFQYLYADFSYTLNLGEKVKLAFGLKAGCTGYSLDTDFQQAEAADPVIFGYEDRWKANIGTGLYLHTNRWYVGLSAPRLLNTDYSGDQDFQSLERISYYFTGGYVFDLSEEVKFKPATLLKMTNGAPLSLDLTANFLFFDKFWLGPAYRIDERAGSFGGLIDFQVSKQFRVGYSYEHPTSDLRPYTSGTHEILLMFELFKSKRIKSPRYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM32</accession>
    <name>A0A5C6ZM32_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">Pyruvate dehydrogenase E1 component subunit beta</fullName>
            <ecNumber evidence="3 6">1.2.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_02515</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>(R)-N(6)-lipoyl-L-lysyl-[dihydrolipoyllysine-residue acetyltransferase] + H(+) + pyruvate = (R)-N(6)-(S(8)-acetyldihydrolipoyl)-L-lysyl-[dihydrolipoyllysine-residue acetyltransferase] + CO2</text>
            <dbReference type="Rhea" id="RHEA:19189"/>
            <dbReference type="Rhea" id="RHEA-COMP:10480"/>
            <dbReference type="Rhea" id="RHEA-COMP:10481"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83111"/>
            <dbReference type="EC" id="1.2.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="2">Heterodimer of an alpha and a beta chain.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.4.1" evidence="3 6"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004739">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006086">
        <property type="term" value="P:acetyl-CoA biosynthetic process from pyruvate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027110">
        <property type="entry name" value="PDHB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11624">
        <property type="entry name" value="PTHR11624"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 6 8" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="Transket_pyr" evidence="7">
        <location>
            <begin position="4"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD90852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="325" mass="35949" checksum="3924CD460105C60F" modified="2019-11-13" version="1">MKTIQFREAICEAMSEEMRRDESIYLMGEEVAEYNGAYKASKGMLDEFGPKRVIDTPISELGFTGVAIGSTMTGNRPIVEYMTFNFSLVGIDQIINNAAKIRQMSGGQFNCPIVFRGPTGSAGQLGATHSQAFESWFANTPGLKVVIPSNPYDAKGLLKSAIRDDDPVIFMESEQMYGDKGEVPEGEYTIPLGVAEVKREGTDVTIVSFGKIIKEAYKAAEELAEEGISCEIIDLRTVRPLDREAILKSVKKTNRLVVLEEAWPFGNVSTDIAYLVQSEAFDYLDAPIVKINTADTPAPYSPVLFEQWLPNKDEVIKAVKKVLYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMQ8</accession>
    <name>A0A5C6ZMQ8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Ribonuclease HII</fullName>
            <shortName evidence="11">RNase HII</shortName>
            <ecNumber evidence="11">3.1.26.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">rnhB</name>
        <name evidence="14" type="ORF">ESY86_01730</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 11 12">Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11 12">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="11">Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 11 12">Belongs to the RNase HII family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.4" evidence="11"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07182">
        <property type="entry name" value="RNase_HII_bacteria_HII_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00052_B">
        <property type="entry name" value="RNase_HII_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022898">
        <property type="entry name" value="RNase_HII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001352">
        <property type="entry name" value="RNase_HII/HIII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024567">
        <property type="entry name" value="RNase_HII/HIII_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10954">
        <property type="entry name" value="PTHR10954"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10954:SF18">
        <property type="entry name" value="PTHR10954:SF18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01351">
        <property type="entry name" value="RNase_HII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 11 12" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="9 11 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 11" id="KW-0464">Manganese</keyword>
    <keyword evidence="7 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 11 12" id="KW-0540">Nuclease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase_HII" evidence="13">
        <location>
            <begin position="15"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="18"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="19"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TXD90710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="201" mass="22525" checksum="35BDF042BED4474D" modified="2019-11-13" version="1">MLKLSPNFSGNALECGTDEAGRGCLAGPVTAAAVILPNTFTNELLNDSKLLSVKNRDLLKPIIEAQALCFAYFHIYPDTIDAINILNASILAMHKSLALLQPQAQFIIVDGNRFKSFGEIPHQTIIKGDSKYLSIAAASILAKTNRDAYMAAIHEEFPMYNWKQNKGYPTKEHRAAIRKFGITKYHRKSFRLLPEEFKLER</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMQ9</accession>
    <name>A0A5C6ZMQ9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Crp/Fnr family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_04325</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012318">
        <property type="entry name" value="HTH_CRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13545">
        <property type="entry name" value="HTH_Crp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00419">
        <property type="entry name" value="HTH_CRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51063">
        <property type="entry name" value="HTH_CRP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="2">
        <location>
            <begin position="10"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="HTH crp-type" evidence="3">
        <location>
            <begin position="146"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD90601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="211" mass="24442" checksum="7F2431034F5C5200" modified="2019-11-13" version="1">MIPLNVLNPFQYQFDDDLLKNIASEGQVREFKKDEIIIDIGQTLTHVPLLLDGNINVLQEDDNGNELLLYVLESGDTCSMSLTCCVAKSKSRIRAIADKDTKVIMIPNDKMSQWFNTNETWRNFILQSYQTRFDEMLETIDTLAFMKMDERLLKYLTNQVKLNANTIISKTHQNIAEDLNTSRVVVSRLLKKLENDHILKLSRNKIEVLEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMW3</accession>
    <name>A0A5C6ZMW3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">RidA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_05930</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11803">
        <property type="entry name" value="PTHR11803"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="SSF55298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="149" mass="16289" checksum="CC9F1868F4072BEE" modified="2019-11-13" version="1">MNEKDTTSEGSVVTPRGAYPHVKQVGDFIFVSGTSSRRADNTIAGVDLIDDMGTKHLNAEVQTREVLKNIDRNLQKVGASLKDVVDVTSFLVNMNDFAGYNKAYAEFFNKETGPARTTVAVHQLPHPDLVVEIKVMAYKPIPANLPTDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN52</accession>
    <name>A0A5C6ZN52_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_05010</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="180"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="229"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="262"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="292"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="347"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD90110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="373" mass="42409" checksum="E6B20A99F34651B8" modified="2019-11-13" version="1">MKIIGYIIQKEFKQIFRNKGMLPIIFVLPLLQLIILSNAATFEVKNIKFAYIDHDHTSTSRALVEKFSASTYFDVLTHFPSEGLASSAMLRGEVDVVLEIPRYFERDLQNEKHHTLGVTINAIDGAAAGVENVYVNQIIQGFNQHLKVDLLQPSDQVIQPLSIDTIPLFWYNETLNYKTFMVPGILVLLVTMITLFLSGMNIVREKEIGTLEQINVTPIKKSQFIIGKLFPFWVIGMALLTIGLIIAKLIFNVPMIGSLPLMYFYTSIYILVVLGIGLFISNFTDTQQQAMFIAWFFTVIFILMSGLFTPIESMPQWAQIVTEFNPIKYFVEVMRMVMLKGSGFMDILPQVLKTLLYALVMNGLAVWSYKKTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNA3</accession>
    <name>A0A5C6ZNA3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Patatin-like phospholipase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_03655</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="1 2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="3">
        <location>
            <begin position="5"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXGXXG" evidence="2">
        <location>
            <begin position="9"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="2">
        <location>
            <begin position="36"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="2">
        <location>
            <begin position="150"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="38"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD90473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="255" mass="28142" checksum="3DEDDD9B6E61EB43" modified="2019-11-13" version="1">MKIGLVLSGGGARGVAHIGVLKALEEQQIEITHIAGTSAGAIVGALYAAGHSWEAILAFFKKVPIFHYKRYALNKPGFIDTSKFHKDLAPFFEEDDFKSLKKELHILATNLVDGTERTFHEGALIKPVLASAAFPGLFTPVIIDEIPYVDGGVLNNFPIEPIKKLCDTTIGVYVNPLEAVSANQLKRSYQVVDRAYHISFVSLCKPKFKEVDVFIAPKKLEKYKMFNLTNMDAIFDIGYAAAVESLKDFKHNNGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNT3</accession>
    <name>A0A5C6ZNT3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_00545</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="108" mass="12869" checksum="0DF417BD991D1ECC" modified="2019-11-13" version="1">MNHIIRGIDNNYWIFTKREKTNETVKIPILPNALAIIEKYKDEAEKTNSLNLATDLLHLFRYTEISDKAVVLICLIHDNMEKFTEYVYYKRELDSRIIPLIVILSRYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZQK9</accession>
    <name>A0A5C6ZQK9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Beta-phosphoglucomutase</fullName>
            <ecNumber evidence="5">5.4.2.6</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">pgmB</name>
        <name evidence="5" type="ORF">ESY86_02860</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="3">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.6" evidence="5"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008801">
        <property type="term" value="F:beta-phosphoglucomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02598">
        <property type="entry name" value="HAD_BPGM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010976">
        <property type="entry name" value="B-phosphoglucomutase_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010972">
        <property type="entry name" value="Beta-phosphoglucomutase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01990">
        <property type="entry name" value="bPGM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02009">
        <property type="entry name" value="PGMB-YQAB-SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="9"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="44"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="114"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="9"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="11"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="9"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="11"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="25"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="170"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity and assists the phosphoryl transfer reaction to Asp8 by balancing charge and orienting the reacting groups" evidence="4">
        <location>
            <position position="114"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity and assists the phosphoryl transfer reaction to Asp8 by balancing charge and orienting the reacting groups" evidence="4">
        <location>
            <position position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR610972-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR610972-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR610972-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR610972-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="229" mass="25470" checksum="6B241324B5B388E6" modified="2019-11-13" version="1">MTKKGFIFDLDGVIVDTAKYHFLAWKKLAKRIGMDFSETQNEQLKGVSRKRSLEKILAWGNKTLSEAEFNQLMSAKNDDYLSYIEKMDDSEVLPDIAKTLDFLIGKGQAVALGSASKNAVPILKKVHLLDKFEAIVDGNDVSKAKPDPEVFLNASELLKVKPEDCIVFEDSVAGVQAANIAKMLSIGIGDKKNLHEADYVFKDFTEISEDFLNDIMSNKINKSSNTTVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZA58</accession>
    <name>A0A5C6ZA58_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lysophospholipase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_19330</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000039">
        <property type="protein sequence ID" value="TXD86762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023083760" evidence="1">
        <location>
            <begin position="19"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="Hydrolase_4" evidence="2">
        <location>
            <begin position="73"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="309" mass="34092" checksum="702768F9C98A0A2D" modified="2019-11-13" version="1">MKLLFAFVLCVTLNFCFAQDPAFTAKDVSINTFIDGTLLTPNGNNTTQLAIIIAGSGPTDRNGNQNFLKNNALKKLAEGLTNNGIATFRYDKRIVKQILKNDVDPNIRFDDFVTDATSVIAYFKEEAEFKKIYVIGHSQGSLVGMLASKQNVAGFVSLAGAGQTIDEVIVNQVAAMDSTLVPPAIKAFERLKQGETTTDYPAVLGSIFRADVQPFMMNWMQYHPQDIIKNLDIPVLIVNGSKDLQVSVDEAKLLEQASDNADLKIIDRMNHVLFIITGGNLENSKSYNESFRPISTELVDVVSEFIKRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAT3</accession>
    <name>A0A5C6ZAT3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_18250</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000030">
        <property type="protein sequence ID" value="TXD87075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="246" mass="28489" checksum="BD411B5AE2751EC0" modified="2019-11-13" version="1">MKKKLEADLISIAHRILRLEGKEEVIKMHAEVAALYETLSVLKFANENFEGHLPTIGNDSSFFGMLDEAFNNKVSDNIEVEDRIYVNMDEKEDDGIYEPVMAKIKDMFAHMPQETEEADELLSQEKVQEKETHHTLEDITSGFEETPIFEPVADAKTNENFRKSLNDKLKNGGLNIGLNDKLAFIKHLFNGKIQDYERVLSQLNTTNSYQEAQRLIKDMVKPDYNHWAGKEEFEERFLGIIERKFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZB54</accession>
    <name>A0A5C6ZB54_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type II toxin-antitoxin system RelE/ParE family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19695</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000046">
        <property type="protein sequence ID" value="TXD86620.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007712">
        <property type="entry name" value="RelE/ParE_toxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05016">
        <property type="entry name" value="ParE_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143011">
        <property type="entry name" value="SSF143011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86620.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="100" mass="12009" checksum="BD4E0B13DE7DE9B6" modified="2019-11-13" version="1">MNREVVMSKTAKRKLEKLFDHLIEQWSLKVKNEFVIKLDDCIEIIKQQPGIFPESLKRKGLRRCVVTKQTTLYYRFNSKRINLVTIFDTRQNPKKLNKEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBK6</accession>
    <name>A0A5C6ZBK6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF4886 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_20525</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000083">
        <property type="protein sequence ID" value="TXD86205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="106" mass="12262" checksum="0E671BF571229A4E" modified="2019-11-13" version="1" fragment="single">SIEKDKCCSPVLENLEQEFNVINESYNLVAKENDLIESNNGTKYFEVRTKYPEIELYEDESHPNENGAFLNACIFYQMMTDKKASDLIYNGEIEPKTAKKLKKIAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBT9</accession>
    <name>A0A5C6ZBT9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000030">
        <property type="protein sequence ID" value="TXD87083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028350">
        <property type="entry name" value="DNAC/ATP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002611">
        <property type="entry name" value="IstB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01695">
        <property type="entry name" value="IstB_IS21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003073">
        <property type="entry name" value="DNAC_TnpB_IstB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IstB_IS21" evidence="1">
        <location>
            <begin position="9"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="245" mass="27933" checksum="B50BCBFE7C958715" modified="2019-11-13" version="1">MNNNQTVEKLKQMRLGAMAELHLQQLKDNRIGSSTADEYLALLTDHQWEDRQNKRIQRLLKQAEFKQQANLADIDYVQNRNLDKNMFERLATLDFITRKENIIITGASGVGKSYLGQALGHQSCMMQYKTIYSNTARLLKKLKLSKVDGTYLKELGKLLKADLLILDDFGLQSFDNHAREALMDIIDDRHNKTSTIISSQIPVSAWYDIIGEGTIADAILDRIVNSSHRIDLKGESLRKGILKNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC23</accession>
    <name>A0A5C6ZC23_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17375</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000026">
        <property type="protein sequence ID" value="TXD87331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="212" mass="24891" checksum="2030ADEC9BCDACE4" modified="2019-11-13" version="1">MDELDLLKKDWQQKARPEEKQLTSKELHPMLFKKSSSIVKTLFYISIAELLLWVLINTIPYFSSKEYRAELAMMYGNEDVLLAITIFSYSIILVFVYLLFRAHQSISVTDTVKNLMKSILKTRKVIKYYVIYNLVMAFLAMCFGLYESIYENPKVSAQFAHFSDKQKFVSTLIMLVVTALFVGVIWLFYRLIYGILLKRLNKNYAELKKLEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC31</accession>
    <name>A0A5C6ZC31_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent epimerase/dehydratase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000060">
        <property type="protein sequence ID" value="TXD86442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="9"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="118" mass="13033" checksum="24E5F6BA0914C593" modified="2019-11-13" version="1">MKKKIALFGASGQTGQHFLELALERGSEVKALARNPKSISQVNPNFEVYMGDVLNIDDVRQVIEDADIVVSLFGHVKGSPEWLQTDGTKNIVQAMKEKNIKRIISPVFVAGTPKLEIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC70</accession>
    <name>A0A5C6ZC70_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_17065</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000025">
        <property type="protein sequence ID" value="TXD87382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="144" mass="16210" checksum="2637FB6FEDE9D48B" modified="2019-11-13" version="1">MSKSRKLKTPGVYVEEISSLSHQVVQLPTAITGFVGYSLTNSYQGKSFQNKAVKIHSLSDYERHFGGTANIQYRLKPVSVPQNQSDAYDVFIQGKAYVIEPEENRFCLYESVKWFFQNGGDDCYIISVGTYGGVKDFRGDLWGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCC9</accession>
    <name>A0A5C6ZCC9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17575</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000027">
        <property type="protein sequence ID" value="TXD87244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022807909" evidence="1">
        <location>
            <begin position="16"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="97" mass="11213" checksum="D76651DF7C45604E" modified="2019-11-13" version="1">MKTIALIVLALVLFAACENLESSIKQEDDSFRTTKTSLKNYNTKSYNTNVYVDTSENYLLRNDITKRQMKMVRITKHVLPTSKVEGLIVTLKNLKWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCR2</accession>
    <name>A0A5C6ZCR2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RagB/SusD family nutrient uptake outer membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_15370</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SusD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033985">
        <property type="entry name" value="SusD-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012944">
        <property type="entry name" value="SusD_RagB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14322">
        <property type="entry name" value="SusD-like_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07980">
        <property type="entry name" value="SusD_RagB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="SusD-like_3" evidence="6">
        <location>
            <begin position="25"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="SusD_RagB" evidence="5">
        <location>
            <begin position="339"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF14322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD87849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="486" mass="54843" checksum="D190F84609C546A5" modified="2019-11-13" version="1">MHRFNMKTSIFYIVFFSLSLLACSDFLEIEPDVQVSIEEQLSTKAGVLEAYSGIYKDIETLTSSNYALYGEVLGGNIAFTPASSTGQVSVFSQIETTYNFEATQFTVDFESYYLACYEIINQSNLLLERSDGFTFFDSEGLNQLKAELLTIRAFAHYQVSLLFAQNYNFTPNASHLGVVYNTETLTAGEDFPARKTMAETYSLIKTDLNDALNLHGNTQLLSGPSFSYFNVLTTKALYARVALQMNDWDTARSFADDIIDNSGIALMSSETYVQEWEQEVAPVSEVILEFTAPRNSDGSVSSSVSEFFSSNQNSNIAKNSASGDLIDLYTDDDIRRSMFIQQDINTNVNGVITPKTYYFTKKFQNDAGTTVIRLSELYLIRAEANARLGSLEQALNDLNTVRTRANLEAITNTSNLLQEIFIERRLELAFENMLFFDILRYKKDVFRDQDCISNLCDVAYPSPFFIQPIPFFSISLNQNIQQNEGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCT7</accession>
    <name>A0A5C6ZCT7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carbohydrate kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18910</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000035">
        <property type="protein sequence ID" value="TXD86883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
        <property type="entry name" value="Carb_kinase_FGGY_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00370">
        <property type="entry name" value="FGGY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FGGY_N" evidence="1">
        <location>
            <begin position="8"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="457" mass="53093" checksum="FF6B7CC3749495F0" modified="2019-11-13" version="1">MKQKVTAVFDIGKTNKKFFLFDEAYQQVHKEYIKFDEISDEDGYPTEDLASLQKWLKQVFNRILATEAYEIKAINFSTYGASFVHLDENGNPLTPLYNYTKQIDQHIIDGFLEKYGPREEFLNTTGCADLSLLNSGLQLYWIKHGKPEIYKNIKYSLHLPQYLSYVFIGIPLSEYTSIGCHTGLWNYEIKDYYDWVYEEGIHKILPPIVSTETSVNMNYNGKRIKIGVGIHDSSAALLSYVRSVKKKFVLVSTGTWSIAFNPFDDDAISKDLEDKEAINYMRINGKPVKATRLFLGNEYKIQVQKLDKHFDVSEDYHRSIKFDYDTYFEIIKDFQHYFKWESITDPDMPSETKIPFDEFEHAYHQLMTELVLLQIKSIKKVIGDDEIKRLYVDGGFSDNEVYIKLLSHYFRDKKLRTTDSSLGSALGAAIAISDSKLNSKFLKNNYSLKKHVPFIVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCV0</accession>
    <name>A0A5C6ZCV0_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">1,4-dihydroxy-2-naphthoyl-CoA synthase</fullName>
            <shortName evidence="3">DHNA-CoA synthase</shortName>
            <ecNumber evidence="3">4.1.3.36</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">menB</name>
        <name evidence="4" type="ORF">ESY86_17235</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4-dihydroxy-2-naphthoyl-CoA (DHNA-CoA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2-succinylbenzoyl-CoA + H(+) = 1,4-dihydroxy-2-naphthoyl-CoA + H2O</text>
            <dbReference type="Rhea" id="RHEA:26562"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57364"/>
            <dbReference type="ChEBI" id="CHEBI:58897"/>
            <dbReference type="EC" id="4.1.3.36"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Quinol/quinone metabolism; 1,4-dihydroxy-2-naphthoate biosynthesis; 1,4-dihydroxy-2-naphthoate from chorismate: step 6/7.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Quinol/quinone metabolism; menaquinone biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the enoyl-CoA hydratase/isomerase family. MenB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.3.36" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000026">
        <property type="protein sequence ID" value="TXD87306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00079"/>
    <dbReference type="UniPathway" id="UPA01057">
        <property type="reaction ID" value="UER00167"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008935">
        <property type="term" value="F:1,4-dihydroxy-2-naphthoyl-CoA synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009234">
        <property type="term" value="P:menaquinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01934">
        <property type="entry name" value="MenB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010198">
        <property type="entry name" value="DHNA-CoA_synthase_MenB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43113">
        <property type="entry name" value="PTHR43113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01929">
        <property type="entry name" value="menB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 3" id="KW-0474">Menaquinone biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="79"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="123"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="253"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between two neighboring subunits</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="268"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between two neighboring subunits</note>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="3">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="3">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="3">
        <location>
            <position position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD87306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="279" mass="31206" checksum="77A1DFC3CE5E047B" modified="2019-11-13" version="1">MKKAEWVTAKTYEDITYKKCDGVARIAFNRPDIRNAFRPKTTSELYDAFYDANEDVNIGVVLFSAEGPSSKDGIWSFCSGGDQKARGHQGYVGEDGYHRLNILEVQRLIRFMPKVVIAVVPGWAVGGGHSLHVICDLTLASKEHAIFKQTDADVTSFDGGYGSAYLAKMVGQKRAREIFFLGRNYSAQEAFDMGMVNAAVPHEDLEATAYEWAQEILEKSPTSIRMLKFAMNLTDDGMVGQQVFAGEATRLAYMTDEAKEGRDAFLEKRKPNFDKKWIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCV5</accession>
    <name>A0A5C6ZCV5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NAD(P)/FAD-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_17365</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NADH dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000026">
        <property type="protein sequence ID" value="TXD87329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003954">
        <property type="term" value="F:NADH dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006116">
        <property type="term" value="P:NADH oxidation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045024">
        <property type="entry name" value="NDH-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43706">
        <property type="entry name" value="PTHR43706"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="373"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_2" evidence="3">
        <location>
            <begin position="10"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD87329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="423" mass="47487" checksum="0EB3B2253356FAC5" modified="2019-11-13" version="1">MNIPATTFPRTVIIGAGFGGIRLASALANKDMQVVLIDKHNYHTFQPLLYQVSSSGLEPDSIAYPVRKILKNHKNSYFRMAVVSHIDAENNSITTNIGDLNFDYLVIATGTRTNFFGNDDIKNNSMPMKTVPQALDIRSLILQNFEKAAITDDVEAKKAFLNFVVIGAGPTGVELSGAIAELKNNILPREYRDLNPDLMAIHLLEGAPRVLPPMSQYASEKAEEYLKELGVTVHCNTLVKHYDGRTVTTNDEKKFESETVIWAAGVTGTPIDGLNPAALHDQTRRFKVNPFNQIEGYAHIFAIGDMALMTTEAWPKGHPQVAQPAIQQGKNLGKNLLNMTKQKPLKPFQYHDKGTMATVGRNKAVVDLKHFKLAGFFSWFIWMFVHLMALVGFRNRVIVFFNWTYNYINFDKAARLIIRPYKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCW7</accession>
    <name>A0A5C6ZCW7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phage holin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_14700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007165">
        <property type="entry name" value="Phage_holin_4_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37309">
        <property type="entry name" value="PTHR37309"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04020">
        <property type="entry name" value="Phage_holin_4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="5"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="115" mass="12098" checksum="0A5AD4CF35ACE089" modified="2019-11-13" version="1">MNFIIRLLITAVIVILLAYLLPGVGVTGFGAAIVVAIVLALLNAILKPILVVLTIPITIVTLGLFLLVINACIILLADAFVDGFSVSGFWIALLFSILLSFCQSIANSMIGKDGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCX7</accession>
    <name>A0A5C6ZCX7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Methyltransferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_15970</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000021">
        <property type="protein sequence ID" value="TXD87656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044995">
        <property type="entry name" value="TMT/HOL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008854">
        <property type="entry name" value="TPMT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32183">
        <property type="entry name" value="PTHR32183"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05724">
        <property type="entry name" value="TPMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51585">
        <property type="entry name" value="SAM_MT_TPMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD87656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="195" mass="22689" checksum="5FF09912368849D5" modified="2019-11-13" version="1">MEDLSENYWDQRYKNQNMGWDLGTVSPPLKAFIDQLEDTSLRILIPGAGNAYEAEYLWAKGFNQVFVVDLSETALERFKKRVPAFPSNQLLQQNFFDLEDQFDLILEQTFFCALHPNLRNDYAKKMLQLLAPKGKLVGLLFDAELYVDHPPFGGHKNDYLELFSPLFHIDLMSACYNSEENRKGQELFIALRKRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCX8</accession>
    <name>A0A5C6ZCX8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="11 12">Na(+)-translocating NADH-quinone reductase subunit C</fullName>
            <shortName evidence="11 12">Na(+)-NQR subunit C</shortName>
            <shortName evidence="11 12">Na(+)-translocating NQR subunit C</shortName>
            <ecNumber evidence="11 12">7.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11 12">NQR complex subunit C</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11 12">NQR-1 subunit C</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">nqrC</name>
        <name evidence="14" type="ORF">ESY86_16515</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na(+) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11 12">
            <text>a ubiquinone + H(+) + n Na(+)(in) + NADH = a ubiquinol + n Na(+)(out) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:47748"/>
            <dbReference type="Rhea" id="RHEA-COMP:9565"/>
            <dbReference type="Rhea" id="RHEA-COMP:9566"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16389"/>
            <dbReference type="ChEBI" id="CHEBI:17976"/>
            <dbReference type="ChEBI" id="CHEBI:29101"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="7.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11 12">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="11 12">Composed of six subunits; NqrA, NqrB, NqrC, NqrD, NqrE and NqrF.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cell membrane</location>
            <topology evidence="11">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11 12">Belongs to the NqrC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.1.1" evidence="11 12"/>
    <dbReference type="EMBL" id="VORO01000023">
        <property type="protein sequence ID" value="TXD87497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016655">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00427">
        <property type="entry name" value="NqrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007329">
        <property type="entry name" value="FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010204">
        <property type="entry name" value="NqrC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37838">
        <property type="entry name" value="PTHR37838"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04205">
        <property type="entry name" value="FMN_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF009437">
        <property type="entry name" value="NQR-1_subunit_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00900">
        <property type="entry name" value="FMN_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01938">
        <property type="entry name" value="nqrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1 11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="11 12" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="11 12" id="KW-0288">FMN</keyword>
    <keyword evidence="8 11 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 11 12" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11 12" id="KW-0915">Sodium</keyword>
    <keyword evidence="10 11 12" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="4 11" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="11 12" id="KW-0813">Transport</keyword>
    <keyword evidence="11 12" id="KW-0830">Ubiquinone</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="FMN_bind" evidence="13">
        <location>
            <begin position="151"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="modified residue" description="FMN phosphoryl threonine" evidence="11">
        <location>
            <position position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRNR" id="PIRNR009437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TXD87497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="262" mass="29137" checksum="F40E4518B9CBC100" modified="2019-11-13" version="1">MEKRTDKNVYTILFAIAMVFVVGSLLAYTASSLKPAITENERIEKQQNILYAMGFNENEENTIAFVSTDTVAGLFASIVKEQLVLEVQDGKLIKEQTREEYMAANNGQEPYLIDVKKQQAQAKQGNPRKLPLFVSEHDGETLYVAPIYGKGLWDAIWGFIAVDKDMIVRGTFFDHAGETPGLGANIKQRYFMDDFYGEHLLTSQGVFKGIAVAKGNNDPKNERKEDYKVDALAGATITGDGVSAMIKADLGLYVPFFQNLNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD24</accession>
    <name>A0A5C6ZD24_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18355</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000031">
        <property type="protein sequence ID" value="TXD87022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023127090" evidence="1">
        <location>
            <begin position="26"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="93" mass="10390" checksum="277F26B53B76F743" modified="2019-11-13" version="1">MKNVYFKILTTLTLLLSVAFGFSQSQLSKSSYEALVSDHLKSVAKDYGFTANDVKDLYINSEVFSKDSQTTSLYINQQFQGIKIHNAVSTVVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD45</accession>
    <name>A0A5C6ZD45_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19625</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000044">
        <property type="protein sequence ID" value="TXD86653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="108" mass="12100" checksum="E5BC4EC05EB57F72" modified="2019-11-13" version="1">MYKGSLAEGEDFKKPFEAVLVAGVAKTLDLKLKDTFFSAHGLVENTLEEHNEHQLIVVGILVETHSVLNNLIETPLETVWELHEEHNHKVSEEGISLKGEEHEMDGAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD83</accession>
    <name>A0A5C6ZD83_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19465</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000041">
        <property type="protein sequence ID" value="TXD86720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022828135" evidence="1">
        <location>
            <begin position="26"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="61" mass="6952" checksum="21297D83CA82A611" modified="2019-11-13" version="1">MKIKISKCLKVLLFVLFFNSIVLNAQQANTDFANQINTVFQNFDKNRLAHGFLSDFGLDVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDN2</accession>
    <name>A0A5C6ZDN2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">T9SS type A sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_15360</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030916">
        <property type="entry name" value="ELWxxDGT_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04534">
        <property type="entry name" value="ELWxxDGT_rpt"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022841277" evidence="1">
        <location>
            <begin position="20"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="Por_Secre_tail" evidence="2">
        <location>
            <begin position="400"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="469" mass="50317" checksum="9BF4E131629C1C16" modified="2019-11-13" version="1">MKKFYILLLPILCAQIGWAQIEQVFDINEGEGNSSPNNLFVFGSAIYFGADDSGGTNSPGDEDLGRELWKSDGTAAGTSFVSNLRTGDAGSSPGNFFEYNGSLYFSANSGSGSVLFSSDGTTAGTAATGDGFVFNPTPLDGLIYFVDTTTGNSLNQFNGTSSALVAGSGSESLIGATMIAYQDKIFCYMDEATDEPTIGRELYAYDPAIDSFNLIKDITESNEDSGISNFTILGTNLYFEALGKLWKTDGTTAGTLAVAAAEAEGIDAINNFYAWNGKLFFEGDNGSDDQLWIYDPTLDTVTNVSNVTGNHDPSDFAPLGDFLYYSGKVEGDTESYLFRTDGAITVRLDSDIFGIDDIVALDGVLYFEAENTVIGRELFKLDPTTLTVSNAIVLAKSVSIYPNPATSVLNLKSASNFDFKYSIIDINGRELQSGNVVNKQISIDLATGLYILQLKAEKQPLVLKKIIIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE31</accession>
    <name>A0A5C6ZE31_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cyclic pyranopterin monophosphate synthase</fullName>
            <ecNumber evidence="3">4.6.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_13320</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate = cyclic pyranopterin phosphate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:49580"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:59648"/>
            <dbReference type="ChEBI" id="CHEBI:131766"/>
            <dbReference type="EC" id="4.6.1.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.17" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061799">
        <property type="term" value="F:cyclic pyranopterin monophosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00886">
        <property type="entry name" value="MogA_MoaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023045">
        <property type="entry name" value="Mo_CF_biosynth-C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012247">
        <property type="entry name" value="MoaC_MogA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036522">
        <property type="entry name" value="MoaC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008284">
        <property type="entry name" value="MoCF_biosynth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002820">
        <property type="entry name" value="Mopterin_CF_biosynth-C_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01967">
        <property type="entry name" value="MoaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036594">
        <property type="entry name" value="MoaC_MogA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00852">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="SSF53218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55040">
        <property type="entry name" value="SSF55040"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00581">
        <property type="entry name" value="moaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00177">
        <property type="entry name" value="molyb_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01078">
        <property type="entry name" value="MOCF_BIOSYNTHESIS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MoCF_biosynth" evidence="5">
        <location>
            <begin position="149"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD88284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="298" mass="32359" checksum="51504560D11C4A36" modified="2019-11-13" version="1">MVDITHKINTLREATAIAIVRTSNEDTIKALQENRVPKGNVFEMARAAGLLGVKKTPELLPDCHPLPIEYTGIEYEINGLEIQISVKVKTIYKTGVEVEAMHGASIVALTMYDMLKPIDKNVEIGTIKLQNKKGGKSAYKIDAEGLTAKVIVCSDTISKGKGEDKAGKAIVSKLEALGIKSERIIIPDEPEDIRSALNTADADIVIFTGGTGVSPRDVTPETIEPMLDLKLKGVEEQMRNYGQQRMPYAMLSRSVAGIKDGKVVLALPGSTKGAAECMDAIFPHVLHVFKVIEGKRHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE45</accession>
    <name>A0A5C6ZE45_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Asparagine synthetase B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_18740</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000033">
        <property type="protein sequence ID" value="TXD86971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="394" mass="44760" checksum="5A2FD70ECC48079C" modified="2019-11-13" version="1">MDAEGQKNHLKAYGVTYWSLNKQMKVKWLLNYRGGSFLLPDTEEIQRECQIRGVSFEVISNAKTEEILNMISSPAENMEAVVLEKAPKIAVYSPKGLKPWDDAVTMVLTYAEIPYETIYDEEVLDDALLLYDWLHLHHEDFTGQYGKFYRAYRAASWYIEDKKRAEALAADLGYDKVSEEKLAVAKKIRDYVVGGGFMFAMCSATDSFDIALSADGVDICEPMFDGDGSDPGYQNKIDYGNTFAFKDFILERNPNVYEFSSIDMTRKRDIPMTTDYFTLMDYSAKWDPIPSMLTQNHTALVKGFMGQTTAFTRDEIKSNVLVMGENKTNGEAKYIHGIKGKGFFTFYGGHDPEDYTHKVGDPQTELDLHPTSPGYRLILNNVLFPAAKKKKQKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEC4</accession>
    <name>A0A5C6ZEC4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptide chain release factor 1</fullName>
            <shortName evidence="5">RF-1</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 8" type="primary">prfA</name>
        <name evidence="8" type="ORF">ESY86_16625</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="5">Methylated by PrmC. Methylation increases the termination efficiency of RF1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the prokaryotic/mitochondrial release factor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000023">
        <property type="protein sequence ID" value="TXD87518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016149">
        <property type="term" value="F:translation release factor activity, codon specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00093">
        <property type="entry name" value="Rel_fac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005139">
        <property type="entry name" value="PCRF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045853">
        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004373">
        <property type="entry name" value="RF-1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03462">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00937">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75620">
        <property type="entry name" value="SSF75620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00019">
        <property type="entry name" value="prfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0488">Methylation</keyword>
    <keyword evidence="4 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCRF" evidence="7">
        <location>
            <begin position="62"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="41"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="modified residue" description="N5-methylglutamine" evidence="5">
        <location>
            <position position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD87518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="358" mass="40671" checksum="04FD72BCB39DD435" modified="2019-11-13" version="1">MLDKLQIIKQRFDEVSDLIIQPDIMTNQKRYVSLNKEYKDLRKLMDKREAYIELTDNLKEAEAIISDGSDPEMVEMARMQYDEAKEGIPKLEEEIRFMLIPKDPEDSKNAVVELRAGTGGDEASIFAGDLYRMYSKYCESKGWKVDTVDYSEGTNGGFKEIQFEVSGDDVYGTLKFEAGVHRVQRVPQTETQGRVHTSAATCMVFPEAEEFDIEIDPKDVRIDFFCSSGPGGQSVNTTYSAVRLTHEPTGLVAQCQDQKSQHKNKEKAFKVLRSRLYDMELAKKQAEDSARRGSMVSSGDRSAKIRTYNYPQSRVTDHRIGLTLYDLSNIINGDIQKIIDELQLAENTELLKASDDHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEE5</accession>
    <name>A0A5C6ZEE5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_16730</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000023">
        <property type="protein sequence ID" value="TXD87538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="150" mass="17194" checksum="59B8488F7480F2DD" modified="2019-11-13" version="1">MLKLHNPTRPYHRLEIDLLFNKVKAQMHQRALAKGGDGIALYTDCYTGETLRGGDRYDYEHIRSSEAVFMKYRDRLTNHEIAEVVNCPENVSVTLRTINQSKGKMRLEDWLENANKVSNHGINGVLARKALANAEMGIQRKVDEILSRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZER3</accession>
    <name>A0A5C6ZER3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_17485</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000027">
        <property type="protein sequence ID" value="TXD87228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11530">
        <property type="entry name" value="NTP-PPase_DR2231_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033653">
        <property type="entry name" value="NTP-PPase_DR2231-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023292">
        <property type="entry name" value="NTP_PyroPHydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021130">
        <property type="entry name" value="PRib-ATP_PPHydrolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01503">
        <property type="entry name" value="PRA-PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="128" mass="14645" checksum="50E5CB2EA31C0373" modified="2019-11-13" version="1">MKQKIEAVKAFHSAFKIGHRETPKAHLGLEKNMLRYKLMREENEEYLEAANADDLVEVADALGDMLYILCGTIIEHGLQHKIEEVFDEIQRSNMSKLGANGEPIYREDGKVLKGPNYFKPNISEILEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEU7</accession>
    <name>A0A5C6ZEU7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_13465</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="169" mass="19192" checksum="63B8E5195C545EC7" modified="2019-11-13" version="1">MKSNNTLKPQDILILLKICTLEKQKWFQHTLAEDLNISQSEISECLSRSKYSGLIDASRKRVNLLNLLEFLQYGIKYVFPQQPGALVRGIATAHSAPPLNNKIQSDQNYVWPYARGNMRGQAIQPLYKSVPKAVLNDQNLHEILALVDAIRVGKVREQNLAISLLKERL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF20</accession>
    <name>A0A5C6ZF20_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF393 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11750</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007263">
        <property type="entry name" value="DCC1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04134">
        <property type="entry name" value="DCC1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="139" mass="15984" checksum="FF377D2A2AC34DE1" modified="2019-11-13" version="1">MIKDLPKDKKLILFDGVCNLCNASILYVIKHDKKDLFRYAPLQSEIGKQILEKFSIDPSKTDSIILFSNENGLSIKSSAALKVAKHLGFPRNLLAAFLIVPAFIRNWVYDYIAKNRYQWYGKKEECMIPTPELKAKFLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF75</accession>
    <name>A0A5C6ZF75_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosome maturation factor RimM</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2 4" type="primary">rimM</name>
        <name evidence="4" type="ORF">ESY86_14070</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Binds ribosomal protein S19.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="2">The PRC barrel domain binds ribosomal protein S19.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RimM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00014">
        <property type="entry name" value="Ribosome_mat_RimM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011961">
        <property type="entry name" value="16S_RimM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011033">
        <property type="entry name" value="PRC_barrel-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002676">
        <property type="entry name" value="RimM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036976">
        <property type="entry name" value="RimM_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01782">
        <property type="entry name" value="RimM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50346">
        <property type="entry name" value="SSF50346"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02273">
        <property type="entry name" value="16S_RimM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1 2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="RimM" evidence="3">
        <location>
            <begin position="9"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="177" mass="20260" checksum="D2360926D67AB783" modified="2019-11-13" version="1">MNKKDCFFLGKIVKKYSFKGELMIKLDTDEPELYEDLDSVFVDLRNNLVPFFIASSQLHKSELLRVKFEDVDTEADADSLLKCGLYLPLEFLPKLDDDKFYFHEIIGFTVEDKHFGTVGIITAVNDSTAQSLFEIDRDGTEILIPMNDAFIEKVDKKNKTIFVDTPEGLIDLYISPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF84</accession>
    <name>A0A5C6ZF84_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_14130</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="404"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="573"/>
            <end position="660"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="660" mass="75844" checksum="D1CE7EE68FD9C2DE" modified="2019-11-13" version="1">MSAQQSKPILDSILELRELANNKTLSPEERLKNALNASELSSKTNQDSTVLNSNRILAYSYLINSEFDRFAMVSQDNLDLAIQLNDSLAIAITSKNLGWYNYAIEGDNLKAYDFYLRAHKYFDALNDLQQKAIALSSIATIQYDEKDYLGCEENAIEVLNILNTLQNQTGEALYEDEYICLNLLGVVTLKLENYEQSIKYHQQAAGLTKYLSEKDMLSLQTENNLAITYRADGNFKKALAIYEDMLERTEILREDPSFYALVIINFNTTKFMTGDYDFRELETEFLKTYKMSDSIDDRYTKLSAAIDVAKFYLANDKKQLAIPFAKESYTISKDIPINELYLESMLLLARLNNGEDSQSYLEEHIQLSDSLLKIERSVRNKFARIRYETDKIEDENQRMSQQRIWLSIVSITLLLALFLLYIVVNQRAKNKQLKFEKDQQKANEEIYNLMLSQQDKVDEARANEKKRISQDMHDGILGRLFGTRLSLDSLNFSEGKDAIRSRANYIVELKGIEEDIRKISHDLNSDFVSGSNFMTIVSELIEKQSKAYKLEYLFDFSDAVDWESISNKTKINIYRIIQESLQNIYKHAEATRVEVRFTLESKSVGLQISDNGKGFDVKKSKKGIGLKNIKSRVSELKGSLRFDADIGKGTNVIINIPYKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFL7</accession>
    <name>A0A5C6ZFL7_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribonuclease P protein component</fullName>
            <shortName evidence="5">RNase P protein</shortName>
            <shortName evidence="5">RNaseP protein</shortName>
            <ecNumber evidence="5">3.1.26.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Protein C5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 6" type="primary">rnpA</name>
        <name evidence="6" type="ORF">ESY86_12740</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.</text>
            <dbReference type="EC" id="3.1.26.5"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the RnpA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.5" evidence="5"/>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004526">
        <property type="term" value="F:ribonuclease P activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001682">
        <property type="term" value="P:tRNA 5'-leader removal"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00227">
        <property type="entry name" value="RNase_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000100">
        <property type="entry name" value="RNase_P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33992">
        <property type="entry name" value="PTHR33992"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00825">
        <property type="entry name" value="Ribonuclease_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00188">
        <property type="entry name" value="rnpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 5" id="KW-0819">tRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD88380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="129" mass="15013" checksum="BC55E1C51C32A011" modified="2019-11-13" version="1">MALTYSKKDKLKSRKLIEKLFSEGRSIAAYPLRMVYLKTSFDDGVAFKAGVSVSKRNFKKAVQRNHIKRLMREAYRCHKSTYFNNSSNEFALMILYIGKETVDFALIEKKMQQLLNKFSEKELTDKTAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFM8</accession>
    <name>A0A5C6ZFM8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Arc family DNA binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_13015</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013321">
        <property type="entry name" value="Arc_rbn_hlx_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010985">
        <property type="entry name" value="Ribbon_hlx_hlx"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47598">
        <property type="entry name" value="SSF47598"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="59" mass="6980" checksum="00F0E4A385F801D2" modified="2019-11-13" version="1">MAKKKAFALRVNEDMLKAIEKWASDEFRSTNGQIEWMLMQYLKENNRLPKSKKTDQSDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFS8</accession>
    <name>A0A5C6ZFS8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_14565</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="286"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="340"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="381"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="21"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="316"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD88105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="418" mass="45985" checksum="089C85021940E672" modified="2019-11-13" version="1">MFSRDRWDEILEALNANKFRTLLTAFGVFWGITILVLLLAMTNGLSNGVTAGFGDFATNSMFMWTQSTSKPYKGLPKGRRFNYDINDVAAIKSEIPNLKYVSPRNSLGGYQGANNVTRGTKTGAFQIYGDYPEYIYQQPMDLLQGRFLSYSDIEAKRKICVIGTGVVKSLYEKNEDALGTYIKVNGVNFMVVGTFKMSNSQGDKEEDANTIYIPFTTFGQAFNQGEDVGWMAITAVDGTSITDMKQQIFDLMKSRHKIDPTDRAIGHYDLSEQFGRINGLFSILSFVGYFVGALVLMSGIIGISNIMLIVVKERTKEIGVRRALGASPWSIKSQVLQESLILTILSGMTGISFAAIVIYVMNTILDRVGPVENFANPSVSMNVVFTALIILVVSGVLAGLIPANSATKMKPVDALRIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFY0</accession>
    <name>A0A5C6ZFY0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_14545</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="8"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="242" mass="27843" checksum="9167A37D0370C8F1" modified="2019-11-13" version="1">MTSEKRTIVFIHYFGGDSGSWKWLDKHLDHNYDSVYLDLPGFNGTEALEELSIRKFAEWIKAQIEGRDLKRYVLCGHSMGAKLALFTAFLMKTNPPEKIILIAPSPPTVENMPAHEKKRMLHHPDEDEAIITVENATCKSMKPKKFDYAVQSQLRIEYKTWGWWIKEGMGTDVSWATKNLDIPTFVICSTSDPVIGMDDIHEEVLPHIQNARLSTFGKSGHLIPMESSRKLAKRINRIMRKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFY4</accession>
    <name>A0A5C6ZFY4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">M20/M25/M40 family metallo-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_12590</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="PTHR12147"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023136114" evidence="1">
        <location>
            <begin position="21"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M28" evidence="2">
        <location>
            <begin position="104"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="328" mass="36786" checksum="5B3A98A23005C5EA" modified="2019-11-13" version="1">MKSITSFFILLLLLSCKSSDKPTTTSNNIPSSELKQTVEYLSSDELLGREAGSDGIEKAAVYLEKQMKANGVQPYFKTYRDTFEFQDTRAAQAGETPKTINAFNVVGVVEGSDPKLKKEYILLGAHYDHIGLGKVVEGDSIANGANDNAAGTSAVLALANHFANAKSNKRSLIFALFSSEEKGLLGSKHLAEKLKEENVNLYAMVNFEMIGVPMKDREYEAYLTGFEASNMAEKMNEYAGSNLLGFLPKAKEYQLFMRSDNYPFYEQFKLPAQTISTFDFTNYDYYHHVDDEAELMDYEHMANLITKMIPVIEKMSNTPTQDIKLYEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG64</accession>
    <name>A0A5C6ZG64_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Polyprenol monophosphomannose synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_13955</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004582">
        <property type="term" value="F:dolichyl-phosphate beta-D-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06442">
        <property type="entry name" value="DPM1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039528">
        <property type="entry name" value="DPM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43398">
        <property type="entry name" value="PTHR43398"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="6"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="240" mass="27224" checksum="35F43F2C5A4D14D2" modified="2019-11-13" version="1">MKDAVVIIPTYNEIENIEAIVRAVFSQKKAFDILVVDDSSPDQTAARVRFLQNEFKGQLHLLSRSGKTGLGTAYIAGFQWSLEKDYQYIFEMDADFSHDPNDLSKLYHACAVGGADLSIGSRYVNGVNVVNWPMSRVLMSYGASKYVRFITRMNICDTTAGFVCYKRKVLETINLKEIKFVGYAFQIEMKFKAYLKNFKIVEVPVIFTDRVRGKSKMSGGIISEAIFGVIKMKFNSFFRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGB8</accession>
    <name>A0A5C6ZGB8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">23S rRNA (Guanosine(2251)-2'-O)-methyltransferase RlmB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rlmB</name>
        <name evidence="2" type="ORF">ESY86_14785</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="L30e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004441">
        <property type="entry name" value="rRNA_MeTrfase_TrmH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013123">
        <property type="entry name" value="SpoU_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46429">
        <property type="entry name" value="PTHR46429"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08032">
        <property type="entry name" value="SpoU_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00967">
        <property type="entry name" value="SpoU_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="SSF55315"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00186">
        <property type="entry name" value="rRNA_methyl_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SpoU_sub_bind" evidence="1">
        <location>
            <begin position="6"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="244" mass="26722" checksum="F85F68E0AF4EE9DB" modified="2019-11-13" version="1">MEKDTTIFGIRAVIEAIKSNENIDKIFIQKGLRGELSLELEQLLKKERINFSYVPIEKLNRLTKKNHQGVVAQIAPITFYDLDNLVMNVIESGKTPLFLLLDQLSDVRNFGAIIRTAECTGVSGIIIQKKGGAPINGDTVKTSAGAIFNIPICKVDHIKDAVFHMQASGIKVIAATEKTDKTLYDVSFKEPCAIVMGSEGKGINPSVLKVVDELAKLPVLGEIESLNVSVACGALLYEALRQRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGD0</accession>
    <name>A0A5C6ZGD0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_10980</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD89005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="260" mass="30572" checksum="675A61543531E5A7" modified="2019-11-13" version="1">MNWNIFCLKYDKREEWAFEQMSYLLFCAELGNRIGLFRYKNQTGIETEPLEKDGEYYGFQAKYYRVPLSGKKSEIISSIKKAKRENPKLNKILFYLNEEFSESTKKGQKKSKFHIDIESEAKKLKLEIVWRVPSHFELQLTLPENKYIYEDFFSLEPNEGKLIDEIKNHNKNILQAIQTEIPFGDKKIKIDRSKIIEEIIKVSNKKENIIISGEGGCGKTALFKEFYSLQNKEIPICIFKATELNVNHINEFVYPQTALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGF6</accession>
    <name>A0A5C6ZGF6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Bifunctional folylpolyglutamate synthase/dihydrofolate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_15685</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004326">
        <property type="term" value="F:tetrahydrofolylpolyglutamate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001645">
        <property type="entry name" value="Folylpolyglutamate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018109">
        <property type="entry name" value="Folylpolyglutamate_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11136">
        <property type="entry name" value="PTHR11136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001563">
        <property type="entry name" value="Folylpolyglu_synth"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01499">
        <property type="entry name" value="folC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01011">
        <property type="entry name" value="FOLYLPOLYGLU_SYNT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01012">
        <property type="entry name" value="FOLYLPOLYGLU_SYNT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase_M" evidence="3">
        <location>
            <begin position="51"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD87753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="405" mass="45075" checksum="864875A11D2479D6" modified="2019-11-13" version="1">MNYQDTVSWMFQQLPMYQNQGKAAFKKDLTNTLVFAEHLNHPERNFKSVHVAGTNGKGSTSHGLASVLQEAGYKVGLYTSPHLKDYRERIKINGKEVSEAFVIEFIKQNTAFLEQHKLSFFEMSVGMAFAYFAEEQVDIAIIEVGLGGRLDSTNIITPEVSVITNIGLDHVQFLGNTLELIAKEKAGIIKPNIPVVVGETQPETETVFRSTAIQNNAAIYFADQLIKSDYVSDLKGAYQKHNMKTVLQTLAILNQNAVPVSEETIKNGLLNIVKNTGLLGRWQVLAEHPKTVCDTAHNKEGLIYTFKQIQTETFEHLHVVFGVVNDKDISAILPILPKDAQYYFCKPNVPRGLDAELLKSRFLENGFKGEAFESVTQALAAARRNASRTDFIYIGGSTFVVAEVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGI6</accession>
    <name>A0A5C6ZGI6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_12870</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="103" mass="11930" checksum="2A19E6E7F9BD2422" modified="2019-11-13" version="1">MEVIKLSYPENDDYLKYVIQKQEKGVAVDCGSVVLKKGQVLPFKTLDAHEITYLVSGKLKVITKDRNEKVMNQGDLIYLNKDEIRKTETLEDSKILFFLFKET</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGJ2</accession>
    <name>A0A5C6ZGJ2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">RecQ family ATP-dependent DNA helicase</fullName>
            <ecNumber evidence="9">3.6.4.12</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_13470</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="9"/>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004589">
        <property type="entry name" value="DNA_helicase_ATP-dep_RecQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014016">
        <property type="entry name" value="UvrD-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027785">
        <property type="entry name" value="UvrD-like_helicase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13538">
        <property type="entry name" value="UvrD_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00614">
        <property type="entry name" value="recQ_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51198">
        <property type="entry name" value="UVRD_HELICASE_ATP_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="6">
        <location>
            <begin position="274"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="7">
        <location>
            <begin position="484"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="domain" description="UvrD-like helicase ATP-binding" evidence="8">
        <location>
            <begin position="1037"/>
            <end position="1351"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="1058"/>
            <end position="1065"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD88343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1603" mass="185371" checksum="B735C2AC50C47395" modified="2019-11-13" version="1">MNKVLYIDIETTKQGKIKDIGALFNGQELHESQFTKLKSWIHQAEYICGHNIVAHDIPLLERVLGNDIFKHKKIVDTLLWSTLLFCDNPYHKLVKGYKIVNDSDYNNPLSDCKLTRQLLIDELNRFKELEENVQQIYVRLLTGSDAYSGFLELIDFQMSNLDAATEIVNLFKSKICDSSNIFQLVKEYPIELAYAFSLINTKEDKSVLAYWVSNTLPKTQEILDNVRFKFCGKETCTYCNSYLNPKKALQSYFGYEDFRSFDPNEDISLQEKTVRAGLSARSFVAVFPTGGGKSLTFQLPALMKGSLSRQLTVVISPLVSLMKDQVENLENRFDITKAAAINGLLSPLERQDAIERVEKGGVQLLYLSPESLRSPTILRILKQRSIARFVIDEAHCFSSWGQDFRVDYLFIADFILSLEEERPFGKIPVSCFTATAKPQVIEDIKKYFKIKLNIELDEYVTRATRTNLKYEVIEIKDSDHKMNTLLSVLENCEKPVIIYASRTKRVEEIHGLIQKAGLSSTYFHGRLDKEVKKDNMDSFMHNEKDIIVATSAFGMGVDKDDVKSVIHYNISDSLENYVQEAGRAGRDEKIQAKCYILFNEQDLSKHFSLLQQTKINQKEIQQIWQALKNLSKYRKEKKISNSALEIAQKAGWDTEIQELETRVKTSIAALEDQGFLKRRLNSPMVFADSLLVPNLSKALKIINQSKNITEIQVQNCSRILQRIVKDDECRIDYLADRTGLRLKEIRDVIELLRELKILGDAKDLTAFINLTQSAKSSRKTLDRYRKIETAMHQILTGDIKISMRQLNQNINDLDVKSEIHELRNILNYWELRNFIQKKRVDRENDLYQIKIKHYDSLNEDIKWRHELTLDVYELLEKFYLKQKENRDSQDKKDLPVSFSMLELKNSNQLFGQIKEEDIKRYEKTLLFLNQIKSIKLEGGFMVSYNRLNIEDIDRSLPRFTLENFNKMSQHYLHKTEQIHIVGEYAKRRLKNYESALAYVNDYFSQPYEEFLAKYFPRRKMEISRPVTPERFKKIAGELDIDQRSIVDDNKSDNILVLAGPGSGKTKVLVHKIASLLLLEDIKPEQFLMLTFSKAASLEFRARARELVPEYTGLIKITTFHGFCFQLLGQLGDLKKSENVIQDCITAINNKEVDISSIINKSVLLLDEFQDVNAVEWKLVQTIINKAKNIRVIAVGDDDQNIYGFRGSSNKNMLEFREKYNATSYALIKNYRSSSHIVHFNNALLKKIPNRLKTQALEPIDKTLKSNIKLIRYNTSYLEKSLAEKVIQDNYVGTRAILVRTNKQALMLNTFLKEFGQKTKLITGLEGFSLDHLFELRTFTDHLKLNTNDAGLIFNTEWADAKNHFVSKHDSSSHLDICLKLIQKFELNYNKQKQLIDWYDYIREIKMEDAIDPDSKAIIIATLHKSKGKEFDHVYLLLEDYDFAKTESKRVLYVGCSRAKLSLQLHCNSSFFDEFDTNSLSVTKFEGTTEQPKHFEVILGHKDIYLGSQKYSKTVNRINTLKSGDQLINDSVQFTDNIAIGCAKQDGGNVLLFSRDFMAKKHDTFIKDGYQLANGSVAYLVYWFDAKEGKEYKVVLPKLMFEKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGQ8</accession>
    <name>A0A5C6ZGQ8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_10520</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="74" mass="8709" checksum="9FBFD11D968291A3" modified="2019-11-13" version="1">MGRPPTRPIKFRDGFYIEIRNKGKNTGIKLHRDTKEQMLRTIKEYELTKDVLILGESKNGKWVDKNPVMHVVEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGV7</accession>
    <name>A0A5C6ZGV7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Deoxyhypusine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08995</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the deoxyhypusine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008612">
        <property type="term" value="P:peptidyl-lysine modification to peptidyl-hypusine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.910.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002773">
        <property type="entry name" value="Deoxyhypusine_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036982">
        <property type="entry name" value="Deoxyhypusine_synthase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11703">
        <property type="entry name" value="PTHR11703"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01916">
        <property type="entry name" value="DS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="323" mass="36613" checksum="0AC2CBA55223A76E" modified="2019-11-13" version="1">MSKGHISQFIEKYYLHFNAAALVDAAKGYEAQLESGAKMLVSLAGAMSTAELGKIFAEMIRQDKVQIISCTGANLEEDIMNLVAHSHYKRVPNYRDLTPQDEWDLLEKGLNRVTDTCIPEEEAFRRIQKHIVKIWQDAEAKGERYLPHEYMYKLLLSGVLEEHYEIDLKDSWMYAAAEKNLPIICPGWEDSTMGNIFASYVLKGELKVSTMKSGIEYMTFLAEWYTENSKNGIGFFQIGGGIAGDFPICVVPMLYQDMERPETPFWSYFCQISDSTTSYGSYSGAVPNEKITWGKLDIDTPKFIIESDATIVAPLIFAYLLDM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHH2</accession>
    <name>A0A5C6ZHH2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Tyrosine-type recombinase/integrase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_08975</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004107">
        <property type="entry name" value="Integrase_SAM-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13495">
        <property type="entry name" value="Phage_int_SAM_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="5">
        <location>
            <begin position="94"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="4">
        <location>
            <begin position="194"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD89181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="393" mass="45695" checksum="023E94B67681BB52" modified="2019-11-13" version="1">MAIITLNTMVHNKKDCIAIRFEYDNALIALMKKMSFVKWSRTKRSWYAEHTQRNRDALLLHLKNSEQQDLKIVSKLQSIIAKPPEIKAARSLSAPQKELLNNFYSYLKGKRYSTSTIKTYSVYVADFIEFQKEKPLAALSNRDVELFIESVFIKRNYSISTQRQFISAMKLFTVFEPSTQIENLELTRPNKSRSLPSVISQQELIRLLQRTTNLKHRAILALLYSCGLRISELLNLKLTDIDIERRQLFVKNSKGRKDRYVGLAESFLPLLSNYLMSYRPKYYFAEGQRGKGYSAESIRSFLRRNCKLAGIYKHVTPHTLRHSYATHLLENGVDIRYIQTLLGHSRPETTMIYTHVRRQDLMKISNPLDVAVQQLRDADKNEANIGLSRGNYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHK4</accession>
    <name>A0A5C6ZHK4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_12810</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023996">
        <property type="entry name" value="TonB-dep_OMP_SusC/RagA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023997">
        <property type="entry name" value="TonB-dep_OMP_SusC/RagA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04056">
        <property type="entry name" value="OMP_RagA_SusC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04057">
        <property type="entry name" value="SusC_RagA_signa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0675">Receptor</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="domain" description="Plug" evidence="6">
        <location>
            <begin position="143"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="5">
        <location>
            <begin position="413"/>
            <end position="1025"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD88394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1028" mass="112969" checksum="55E9ACAA9D3319D0" modified="2019-11-13" version="1">MHNYLLSVLFKLNEFIMNNKKSNSNKSVNGRYKFSFCVLILLLCFSQKNSAQNSVSGKVLDEYKVPLIGATILEVGTNNGVVTNFDGEFEIVLKNENASLKISYVGYITKQIKATASDLEVIMEADVSALNEIVIIGYGESKQKDITGSVSSVEMEDIQSQPSSNIGDAIQGRAAGVTVITSGQPGNNPTFRIRGSGTIGNNDPLIVVDGMPLNGGLNQVNMKDVASFQVLKDASSTAIYGSRGSNGVIIITTKRGKKGKGRLDVDVFTSIQQATSLLEVLNAEQFGTLSNEILANGGQQPNPDFANPSALGNGTDWLDAFFTTGKQTNATLSYSQGSEKSNLYTSLNVFDQDGIIINSEYTRYILQFNSDTEINDHLKFGNSLKLNYDIKKNGDNNIQNALLSLPTQPIFRDNGNYSGPIGQPIYSGDVENPIGKSNSVENSTKGYNLQGVVYAELSFAKHLKFKTLLGVEANFFDTRTWAPSFSWDSDVSENAFLSESSNKSTTLLWDNTLTFNKDYDSGSSLTAVIGTSAQENQFKFISGSIQGFPSESTQTLNNGLLQPTINGSGSEWSIFSFFARGQYDYKDKYYLTATVRRDGSSRFGEGNKYGTFPSAALAWRVSEESFLENSNVINDLKLRLGYGVTGNQEIGNYSFASAYNTNLYNFNGSFVTAAVPTVLPNSNVQWESQKQLNVGIDASLFNHFIDVTIDGYIKNTEDMLVPQTVPITSGYSDIFVPFINAGKLRNKGIELLLTTYNMNRDKFRWSTDFVFAYNDNEVIDINSDTPLTTGGIGLNYTLARIQPGYPINVFYGFVQEGIFQTQNEVDTHAVQVPGTNPATSTSPGDIRFKDLNSDGVINDEDRTFIGNPNPDITYSLNNTFTFGNFDLSVFFQGVYGNDIFNANRLYTENMSVTTNQSTAVLNRWRGPGTSNSIPRAVFGDPNNNNRQSTRYIEDGSYLRLKNVNLSYNVPTDFYDNKTFSSIKVYVSGQNLFTITDYSGFDPEVGPNGIDNNIYPVTRTFTLGATLGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHQ1</accession>
    <name>A0A5C6ZHQ1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CcoQ/FixQ family Cbb3-type cytochrome c oxidase assembly chaperone</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="61" mass="7246" checksum="2BE4A32D7A52BBF5" modified="2019-11-13" version="1">MLKFVKNHMESITGIEIYPMISLIIFFTFFVLLFWWVVTAKKEYITNVSNLPLEDENTTDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI10</accession>
    <name>A0A5C6ZI10_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DASS family sodium-coupled anion symporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_06315</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031312">
        <property type="entry name" value="Na/sul_symport_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001898">
        <property type="entry name" value="SLC13A/DASS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00939">
        <property type="entry name" value="Na_sulph_symp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00785">
        <property type="entry name" value="dass"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01271">
        <property type="entry name" value="NA_SULFATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="40"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="84"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="122"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="213"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="270"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="295"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="334"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="363"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="390"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="413"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="453"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD89815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="489" mass="53436" checksum="0C077C277478265C" modified="2019-11-13" version="1">MTLTKRIGLLLGPLLFVLIILFFKPEGLSAEANAVLASTAWIAVWWITEAIPIAITALLPIVLFPLTGGLELSTTTSAFGHKYVFLYLGGFIIAITIEKWNLHRRIALNIIKIIGSDVRKIILGFMVATAFLSMWISNTATSVMMLPIGIAIIKQLKDNPDTAEDENEIFGKALMLAIAYSASIGGIATLIGTPPNLVLAGVVHDIYNYEITFLQWFIFGFPISMLLLFICWKYLTSVAFTFKQKTFPGGTQEINRLLKALGNISYEEKLVSIIFALTAFCWITRSFLLQGFLPALDDTIIAVFFAIVLFLIPSKDKKERLINWDEAVKLPWGIILLFGGGMALAQGFESSGLAAWIGSQMTLFAGVTTILLIFLLIAAVNFLTEITSNLATTAMLLPVLAPMAITVDIHPFILMVGAAVAASCAFMLPVATPPNAVVFGSGYLRIPDMVSKGIVMNVISIIVLTLFVYFVLPELWGIVVEGFPAELRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI27</accession>
    <name>A0A5C6ZI27_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_06180</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0675">Receptor</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="483" mass="55825" checksum="C40EE451DCB7F1E9" modified="2019-11-13" version="1">MEITLKGDKEFDEIPSLKTKCLRINLNENIYGTFAEIGAGQETVRQFFRAGGGSGTIAKAMSAYDKAFSDAIYGIEDDKRYVTEARLRKMLNHEINLMEQRLSREEHPNKMFFSYANTVATIDFAKKYKGHGWVGIKYQVDAEEAYNEIVLHLRFKENDARLQQETLGVLGTNLIYGAYYKYNEPKKLLRYLYDHLDKDQVEIDTINFAGPVFENVDNRLMSLQLVKNGMTDAVMFAPDGNNVLPAKVLYKKNILALRGSFRPVTKVNMDMYKKSYDMFINENKVDLDKTQVIFEITLSNLRAEGEIDEQDFMDRAKLLCSLGQTVLISNFQEYYKLVEYFSQYTKSRMGLAMGVNNLVDIFDEKYYRHLSGGILEAFGKLFFKDLRVYLYPMKNDDGTITDSENLKVHPRMKELYKFFKYNGKVVDITDYDESILTIFSRNVLKAIADGKDDWDHMLPPGVSKLIKEKSLFGCETEQVYLDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI48</accession>
    <name>A0A5C6ZI48_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GNAT family N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11655</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="10"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="150" mass="17260" checksum="387A71BF5343BB05" modified="2019-11-13" version="1">MIKKLQNHKLEISKQMHSLFQLSYAVEAKLLDAVDFPPLKRPIESYQESKTTFYGYLEHGVLAGIIEISHSQNHTRINSLVVSPMYFRRGIGGTLLEFVFDAFDSAVFVVETGANNKPATQLYKSLGFKEIEQWETDFGIRKVRFEKRVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI69</accession>
    <name>A0A5C6ZI69_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Probable transaldolase</fullName>
            <ecNumber evidence="9">2.2.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">fsa</name>
        <name evidence="9" type="synonym">tal</name>
        <name evidence="10" type="ORF">ESY86_06465</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D-fructose 6-phosphate + D-erythrose 4-phosphate</text>
            <dbReference type="Rhea" id="RHEA:17053"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 9">Belongs to the transaldolase family. Type 3B subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.2" evidence="9"/>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00414"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016832">
        <property type="term" value="F:aldehyde-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004801">
        <property type="term" value="F:transaldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00956">
        <property type="entry name" value="Transaldolase_FSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00494">
        <property type="entry name" value="Transaldolase_3b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001585">
        <property type="entry name" value="TAL/FSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022999">
        <property type="entry name" value="Transaldolase_3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004731">
        <property type="entry name" value="Transaldolase_3B/F6P_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018225">
        <property type="entry name" value="Transaldolase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033919">
        <property type="entry name" value="TSA/FSA_arc/bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10683">
        <property type="entry name" value="PTHR10683"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00923">
        <property type="entry name" value="TAL_FSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00875">
        <property type="entry name" value="fsa_talC_mipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01054">
        <property type="entry name" value="TRANSALDOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 9" id="KW-0570">Pentose shunt</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0704">Schiff base</keyword>
    <keyword evidence="6 9" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="9">
        <location>
            <position position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD89841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="217" mass="23499" checksum="D1D00505823F60E1" modified="2019-11-13" version="1">MKFFIDTANIEQIKEAQDMGILDGVTTNPSLMAKEGITGHDNIMKHYISICNIVDGDVSAEVIATDYEGMVREGEALADLHGQIVVKLPMIKDGIKACKYFSDKGIKTNMTLVFSPGQALLAAKAGATYVSPFIGRLDDISTDGLNLIAEIRLIYDNYGFETEILAASVRHTMHVIDCAKLGADVMTGPLSSITGLLKHPLTDNGLAKFLEDYNKGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI91</accession>
    <name>A0A5C6ZI91_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_09040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022686192" evidence="1">
        <location>
            <begin position="22"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="293" mass="31091" checksum="E2A2EB785363DA1A" modified="2019-11-13" version="1">MKTNITILASLCLLIPGLILAQSPVSGFMKKAGEGALVLSYSNESYDEVYLVPEEIDGVPVFNDVSISSISLYGEIGISDNFNLVLNLPYIKSEGNASDAVLTNNGFENERKGVQDLKIYAKYRFLQSNLGNNTLDLIAAAGFETPLGDYRADEGLQSIIAIGNEATSFNMLGIATFKNNSGVFATGQAGYSFKGNNAPHALISELKIGYAASKFYVDAFVANQLSDKSGVDILGEGFTGFFPATRVNYTRVGVNGYAPLYGGIGLTAGANAYVAGRNLGKSTGFYGGLVYSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIH2</accession>
    <name>A0A5C6ZIH2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_09650</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="126" mass="14682" checksum="AF4DF4D72FC659B8" modified="2019-11-13" version="1">MKTQANIILEGLKQFYGSDTYYEIPLIKTRYTCGIKYLAENANCYWLVSDASLMAKTLMTKTEFVTIDFKRLSRKKQDYTGHEAQLIYTDGNENVLECHGYSVSDFPLDELRLFFVNNMLMLPSEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIH3</accession>
    <name>A0A5C6ZIH3_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PSP1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_07605</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007557">
        <property type="entry name" value="PSP1_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04468">
        <property type="entry name" value="PSP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51411">
        <property type="entry name" value="PSP1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PSP1 C-terminal" evidence="2">
        <location>
            <begin position="116"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="358"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="365"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51411"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="391" mass="44655" checksum="734F4FDC14152AC4" modified="2019-11-13" version="1">MSCTSCSTSKDGQPKGCKNNGTCGTDSCNKLTVFDWLANMSLPQGEAPFMGVEVRFKNGRKEFYKNTENLTLSIGDVVATQAKAGHDVGMVTLTGELVRIQMKRKKVRLDDEENVLKIYRKASQRDIDIWSDARDKEEPMKVKARRFAIDLKLKMKISDIEYQGDASKATFYYTAEERVDFRELIKLFAREFRTRIEMKQVGFRQEAARLGGIGSCGRELCCSTWLTDFRSVSTSAARYQQLSLNPLKLAGQCGKLKCCLNYELDSYLDALKAFPKSDTKLFTEKGKAVCQKTDIFKGVLWYAYEGEWMNWHVLTTDQANEIIDKNIKREKVTSLEEYAVDLVQDTKTSFENVVGQDSLTRFDSPKRNKKRKKKSGNQQNRNKKPRPDAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIP1</accession>
    <name>A0A5C6ZIP1_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">Cysteine desulfurase</fullName>
            <ecNumber evidence="4 6">2.8.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_08310</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[sulfur carrier]-H + L-cysteine = [sulfur carrier]-SH + L-alanine</text>
            <dbReference type="Rhea" id="RHEA:43892"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="EC" id="2.8.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 5">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.7" evidence="4 6"/>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031071">
        <property type="term" value="F:cysteine desulfurase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006534">
        <property type="term" value="P:cysteine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06453">
        <property type="entry name" value="SufS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010970">
        <property type="entry name" value="Cys_dSase_SufS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01979">
        <property type="entry name" value="sufS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="7">
        <location>
            <begin position="24"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD89382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="406" mass="44727" checksum="6DB5D9D8A003EC4A" modified="2019-11-13" version="1">MLDVQKIRTDFPILNRKINGKPLVYLDNAATSQTPQQVIDVIVDYYSNYNANIHRGVHTLSQEATDLYEGARLKIQEHFNIKHSHEVIMTAGTTHGINLVASGFSNLIEKGDEILVSALEHHSNIVPWQMLCERTGATLRVIPMDDNGQLIMADFGAMLSERTKLVFVNHISNALGTINPIETIIKKAHEVNAAVLIDGAQSCPHIKPDLQALDVDFYVTSAHKICGPTGVGMLYGKQDWLNKLPPYQGGGEMIAEVTFEKTTYADLPHKFEAGTPNISGGIAFGAALDYMNAIGFEAIAEYEHELLEYATDKLSQIEGLKIYGPKDLNEKTSVISFNIQGIHPYDIGTILDKMGIAVRTGHHCAQPVMDFFKIPGTVRASFAFYNTKAEVDALVEGVKKAKMMLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIR1</accession>
    <name>A0A5C6ZIR1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="176" mass="19995" checksum="A433C5A455DEDC11" modified="2019-11-13" version="1">MKIQHILMPFLVALLVACGSSQRVITADGSVYQVKGNKIMNAGTDVSETLSEDQKASIKTLVAEQKEAKATAEKLQEELEEKQDRLNDAIKETQKKQEALIEKQEALDEKLEAKEEATADFLKAKKRLADKTKKYQRLKDKGKLSPRDDEKWQEKLKDYQQDIDDAQAKMDALNKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ11</accession>
    <name>A0A5C6ZJ11_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_09605</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022679694" evidence="1">
        <location>
            <begin position="23"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="138" mass="14874" checksum="E84DAB70D291EEE4" modified="2019-11-13" version="1">MRHLPKLTIILVLMIYSGRLQAQASQVYFTLESTNVSFSGQSLNIASAIVLQGSGLRWTQENDGTVNITDFQVTGTSGEWDQASFMGALTHTIAMDGDHLGTFVLEGTTNGVTAILSVDVDGAVAHYTFSINSINFQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ50</accession>
    <name>A0A5C6ZJ50_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ankyrin repeat domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_06010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="SSF48403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023115938" evidence="2">
        <location>
            <begin position="21"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="69"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="127" mass="13639" checksum="3DE1A2FF87276574" modified="2019-11-13" version="1">MKKTAVIIAIALGCSINALNATNEIATISTKEVVVNQTISPFCLSILKGDYETAKKLIDLGADINAKSLGLTPAMYAAKFNRTDILKLLVEKGAKLKVKSDKGMTAEKYAELSNATDALSYLRQLES</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ71</accession>
    <name>A0A5C6ZJ71_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Crp/Fnr family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05595</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="1">
        <location>
            <begin position="30"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="186" mass="21698" checksum="4FB169F40F29D95A" modified="2019-11-13" version="1">MDKSILELLKKAGNFSEKESILLKQELQHRKLNKEDFLLEKGTTCSSLCFVISGSFYQYNVDLDCNKNVIDLNIPNDWVINHKSFTTRKPSEYAIQAYEDSFIYELSINAIHRLIAKSQSFLQMGKILEESTSRIDFFDNNNTPDEKYCFILKNKPDLLQKFPQTILASYLKITPETLSRVRKRIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJD5</accession>
    <name>A0A5C6ZJD5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="245" mass="27506" checksum="76CC11CB88038CB4" modified="2019-11-13" version="1">MLNVILVVVGLILLTILIVWLIDRFVPKGIKPIIHIVLWAAIIYLGYLTFDSVYGEIKFNELKTERYKVVIKKLKDIRDAELAHRTVTGEFNGDFDNLIRFVDTAHYTIVERRDSTVVDAELTKRFGGVETTRDIVILDTLGTVPVKDSLFGADTRYKTMMNLPENIGPEGAKFELNAGRLSGSGIPVFEAFVKKSVVLYDQNKNLIAKEEEVMSVDGVRGPTIKVGAMDEVYTKGNWPKNLAQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJE7</accession>
    <name>A0A5C6ZJE7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13174">
        <property type="entry name" value="TPR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="135"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="203"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="469" mass="54427" checksum="FF3C71E98212BD5F" modified="2019-11-13" version="1">MEFSQPNDDNLSLARFESMLKTNNVLFFDSEEFENIIFHYLESGKIPLAKKAIKMGLEQHPSSTNLCLFQTEMFIIDNKFDAAEQLLNQLYEIEPNNEEIYIQKANLLSKSDQHEKAVGTLLTALDMVKEEEGVAELYVLIAMEYLFLEQFENAKHYFQKCLDINYEDYSALYNIIYCYDYLGEGEEAISFLNSYLDGNPYCEIAWHQLGIQYYAIKDYDKALAAFDFAIISDDTFVGAYLEKGKVLEKKKQFKDAIENYKITLALEEPTSFALLRIGYCQEKLGNDDLAVQSFYKTVHEDPLLDKGWIAITKFYNRKKNYQKALFYINKAINIDGENVVYWKLYAQINHRLNFIEEAEQGYKRTIELGNYELSTWLARADLLIALGEYEASVLNLIQTAEFYPEIAEIEFRLAGLHFVLHESSKGHYHLKNALLLNPDFKYILEELFPKVLQKPSVQQVISKSKNSAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJE8</accession>
    <name>A0A5C6ZJE8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10995</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046077">
        <property type="entry name" value="DUF6095"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19589">
        <property type="entry name" value="DUF6095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="79" mass="8786" checksum="10F45B780FD79707" modified="2019-11-13" version="1">MEETNRTDKDILVKGVKTMALSAALMFLGPTLLYIALSNKEKPLYIPILIVALIACGSAIYFGFKGLKTIMDSMFKKRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJF5</accession>
    <name>A0A5C6ZJF5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase family 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_09030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="7"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="231" mass="25823" checksum="10F4ADE3435FAB84" modified="2019-11-13" version="1">MSPRIKVIIPAYNEANSIALVIKDIPQFVDEIIVVSNNSNDATEVNAKNAGATVLSQPLRGYGNACLKGMDYISKASDKPDIVVFLDGDYSDYPEQMTKIIAPILEDNIDFVIGARDKALRETGSMTFPQIFGNWLATSLMSLFFNAKFSDLGPFRAIKYHKLLQLQMEDKTYGWTVEMQLKAIRQKLSYTEVPVNYRNRIGVSKVSGTIKGAIFAGAKILGWIFKYSFKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJI6</accession>
    <name>A0A5C6ZJI6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">M28 family peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_08825</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="PTHR12147"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022679356" evidence="1">
        <location>
            <begin position="21"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M28" evidence="2">
        <location>
            <begin position="95"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="Por_Secre_tail" evidence="3">
        <location>
            <begin position="386"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="458" mass="50181" checksum="DF1A6BCC21112631" modified="2019-11-13" version="1">MKILLHLVLLLFLGSLTVSAQSIQDLIDQVNIEKLETILNEFSGEQSSSVNGNTVTILNRQQANNELAADYLVERLSAMEKLSITDQAFNTNGRNIIATQVGTVNPESVYIVCAHYDSTANYCADDNATGVAAVLEIARILSTQCLENTIVYALWDEEEIGLLGSAYYAAQAAANADAILGVLNIDMMGYDGDAVGTPGDNQFDIDYRDIAGSTAMKNDIISVLNTYTFDLKVVEVNPGTYSSDHSSFWDQGYSALLVGESWETNDQTPFYHSSADRVATLDLPYFHEMVKLVLGYMVTKAELVAFENGVTSMNGLLTATQNASNYQWINVETNTPILGETNQSFTPLANGIYAVEISLGSCTEQSEPIVVDNLGVNTLSTEDIRVYPNPVNDEIRLSYSENFESLKLKLYDVSGKLVKEETLSNSKSRLSIKSLPKGIYFLKVVASEKSGIFKIIKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJI8</accession>
    <name>A0A5C6ZJI8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TolC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_05040</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023018504" evidence="2">
        <location>
            <begin position="22"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="435" mass="49212" checksum="74984C8661B2CD89" modified="2019-11-13" version="1">MKNNVLAITLCFLGLTASLQAQEIIPLTKTEVLNRVNQDNTSLKISEQEFIEARADYRQTNAVFLPNITASHTGIATTNPLMAFGSKLNQGILTQNDFNPVLLNNPSQIENYATKFEIQQPLINVDGIFQRKAAKSKMDAMALKTERTADYLVFEVEKAYMQLQLAYKGVDVLDQALKAANSNKKLADNSFKQGYLQRADVLNVEVRVTEVQNQLQMAKSNVQNASNYLSFLMSDDTYVAYMPTDSLTVSSFEMEKTSISENRSDIKAMQLATNAYEAMNKADKMAFLPRLNAFGSYELYDDQIFQGGSNGYLFGAQLTWDLFQGSKRFGKAQKSKAEFEKSKLQYKQYVSQSNLDLNKAKRALIDAENKLSLTSLALEQSEESLRIRTNRFKEGLEKTSDLLVSETQFAQKQLEYYQTIFEYNYAKAYVQFLAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJQ2</accession>
    <name>A0A5C6ZJQ2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Acyloxyacyl hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_04650</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018550">
        <property type="entry name" value="Lipid-A_deacylase-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09411">
        <property type="entry name" value="PagL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="366" mass="41612" checksum="18A4ED790BAE0D04" modified="2019-11-13" version="1">MTRPSHSVILYLFVSISLYSQTDSLRIEESRPTFIGVNLDYGFLIRHTESLRDMDNSHPSALSVDLSKLLLTQEAWDFCNCFPKLGVNLSYWNWDNPDVLGNGVLAMGYVEPYFRTQKKTNIFLTMGIGGAYLTNPFDEGSNPNNESYSTHLSFALMAGLGINYRLTEKLNIRLAAKYNHTSNGGVSTPNKGLNFPTLSLGVHTSLEDVQYPSLSKIGKREAPEDKTRFSLIHFSGWSNANVGDKDKFYVFGLTANYSRWVGNRSAIMVGTEWIFDYSRKEQIKIDGGNSSFLQGSALVGHEFWLGRVNFSQQLGVYYFNEYRTTDDVYQRYGLTYSFNKHIFAGFNLKAHRHVADFFDLRIGYTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJR8</accession>
    <name>A0A5C6ZJR8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF433 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_03555</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007367">
        <property type="entry name" value="DUF433"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04255">
        <property type="entry name" value="DUF433"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="74" mass="8423" checksum="2E5431B2A0C0760B" modified="2019-11-13" version="1">MIDFTKYITIDPNKRFGKPILKGTRISVYDVLNWLANGMTNDEIIADFPELDENSIKACLSFAASRENKIRIVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJT5</accession>
    <name>A0A5C6ZJT5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA starvation/stationary phase protection protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_04100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the Dps family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01043">
        <property type="entry name" value="DPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002177">
        <property type="entry name" value="DPS_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008331">
        <property type="entry name" value="Ferritin_DPS_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42932">
        <property type="entry name" value="PTHR42932"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00210">
        <property type="entry name" value="Ferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005900">
        <property type="entry name" value="Dps"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01346">
        <property type="entry name" value="HELNAPAPROT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ferritin" evidence="3">
        <location>
            <begin position="18"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD90558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="159" mass="18645" checksum="E50BAA36E51449CD" modified="2019-11-13" version="1">MKTNIGISKEHREKTVGILSKLLADEFLIYTRTLRAHWNLEGHDFHTKHLFFEEHYNAIKLFTDSVAERIRKLGHYAPATMAEFLELTHLSEKYEGDNTSLEYIEVLLKDHDSVIKYIRENISKVEDEYKDVGTGDFLTGLMQEHEEMAWMLRSTIAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK26</accession>
    <name>A0A5C6ZK26_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amidohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08475</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="1">
        <location>
            <begin position="5"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="258" mass="29506" checksum="E60A4486C5488482" modified="2019-11-13" version="1">MKDKLKVAILQSDLVWENADQNRINFSNQMTSILEPVDLIILPEMFTTGFSMNPESIYETMNGNTVSWLQELAIQKEAAITGSIVIKENENYYNRLLFVTPNGHIEHYDKKHTFTLAGENKVYSAGSKLLSIDYLGWKIRPLVCYDLRFPVWSRNTNEYDILIYVANWPKVRIAAWDALLKARAIENMSYCIGVNRVGLDGNNHEYSGHSAVYDVMGERIDSISEEKEIAIVTLDKDHIATQRAKLGFLKDRDSFTLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKH4</accession>
    <name>A0A5C6ZKH4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Acyl-CoA thioesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_06485</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016790">
        <property type="term" value="F:thiolester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002864">
        <property type="entry name" value="Acyl-ACP_thioesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01643">
        <property type="entry name" value="Acyl-ACP_TE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="129" mass="15446" checksum="346A08E915FA8076" modified="2019-11-13" version="1">MQTYEKHIVVAQEDIDIRSHVNNVRYVEWVQDIAQEHWDSKITEKLKKTYYWIMLSHFIEYKAEAILGDVLRLETFVTKADGVRSTRQVRIYDKNTNKLLTSSETMWCFMSHKTNRPTRITEEIQSLFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKL9</accession>
    <name>A0A5C6ZKL9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Methylenetetrahydrofolate reductase</fullName>
            <ecNumber evidence="10">1.5.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">metF</name>
        <name evidence="11" type="ORF">ESY86_02165</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2 10">
            <text>(6S)-5-methyl-5,6,7,8-tetrahydrofolate + NAD(+) = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:19821"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:18608"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.5.1.20"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>(6S)-5-methyl-5,6,7,8-tetrahydrofolate + NADP(+) = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:19817"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:18608"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.5.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 10">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 10">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 10">Belongs to the methylenetetrahydrofolate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.20" evidence="10"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106312">
        <property type="term" value="F:methylenetetrahydrofolate reductase NADH activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106313">
        <property type="term" value="F:methylenetetrahydrofolate reductase NADPH activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00537">
        <property type="entry name" value="MTHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029041">
        <property type="entry name" value="FAD-linked_oxidoreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003171">
        <property type="entry name" value="Mehydrof_redctse-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004620">
        <property type="entry name" value="MTHF_reductase_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02219">
        <property type="entry name" value="MTHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51730">
        <property type="entry name" value="SSF51730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00676">
        <property type="entry name" value="fadh2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0274">FAD</keyword>
    <keyword evidence="6 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-0520">NAD</keyword>
    <keyword evidence="8 10 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD90787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="318" mass="36214" checksum="9458DF6BADD839F3" modified="2019-11-13" version="1">MKVTEHIKKANSTTQFSFEILPPLKGHDIQSIFNNIDPLMEFHPPFIDVTYHREEYIYKELENGLLKKLVVKKRPGTVGICAALQNKYNIDAIPHILCGGFTREDTENFLIDLDFLGIDNVVALRGDAVKSETYFKPEKEGHCYATDLVAQIRDMNKGNYLHAELENASKTNFCIGVAGYPEKHMEAPNMYSDLHFLKKKIKNGAEYIVTQMFFDNKKFFDFVDKCQKEGITIPIIPGLKPISTKKQLNMLPHRFHVDLPEALISEVLKCKDNAQVRQVGVEWCIEQSKELQKAGIPVLHYYSMGKSDNIKAVASAVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKN4</accession>
    <name>A0A5C6ZKN4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_06865</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="120" mass="13927" checksum="AE0D2D87D0A20137" modified="2019-11-13" version="1">MKTINDLEEKVLFFQDALNDRNFKAAKRSLHPNFLYQSLLGIEKGGSNYIDILKTSYRTYHLLKIFSNRDSVCSIYELKIPEQKNTIVCALYGFRENKIATLQLFQNLLTSVKIKSEDEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKQ1</accession>
    <name>A0A5C6ZKQ1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GLPGLI family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_02330</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005901">
        <property type="entry name" value="GLPGLI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09697">
        <property type="entry name" value="Porph_ging"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01200">
        <property type="entry name" value="GLPGLI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022670229" evidence="2">
        <location>
            <begin position="23"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="297" mass="34068" checksum="CC4C48CE196B0221" modified="2019-11-13" version="1">MKQFTAKLSIVFIFMIGLNAAAQDFQGQAIYQAKTSVDMDSWGNGQMSEQQKKMIAERMKNMLEKTYVLNFNRSEATYKEEEKLDAPGSGGGMWSGMMSSFTGGPQYKNIKENVLLQEQEFFGKAFLVQDSLPNLEWKLENETKQIGQYTCFKATTTKKADEMDFMSMRRKNKEDDDKKEAEKKNGKKVQDSTKTEADDPFDELEVPKYIIVTAWYTPQIPVSTGPAEYHGLPGLILEVNADRTIMLCTKIVMNPKDKQNIDRPKKGDVVTRDEYNKIMKDKIQEMREMYGGRGRRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKS0</accession>
    <name>A0A5C6ZKS0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07085</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="62" mass="7455" checksum="4E882C299624DC5A" modified="2019-11-13" version="1">MIKFFRKIRQKLLTENKFSKYLLYAIGEIVLVVIGILIALQIDNNHNYNEQRRVEQEYLLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKS6</accession>
    <name>A0A5C6ZKS6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Group III truncated hemoglobin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_03490</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019825">
        <property type="term" value="F:oxygen binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009050">
        <property type="entry name" value="Globin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012292">
        <property type="entry name" value="Globin/Proto"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46458">
        <property type="entry name" value="SSF46458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="131" mass="15583" checksum="E0170D9FC9CB7262" modified="2019-11-13" version="1">MKAIETREDIFKLVSTFYIKVRAHEVLGPIFNESISDWDRHLDHLTTFWESSLFIGRKLEKPYVGNPLEAHIKVDEAFDNSITELHFGYWLNLWVETIDQLYEGEIAENAKRRARKMGSFMYLNIFQARQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL50</accession>
    <name>A0A5C6ZL50_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_02005</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="260" mass="28915" checksum="F6C5D7FEE913D1CE" modified="2019-11-13" version="1">MAPIKFEEDIKKRMEQRKIQPSEDAWEKLSHALDAEQKNKSKPLIWFMGIAASVMGVLLVSSLFFKASEGLPVRQNTVATEANESTSSISNSENESKSVKKVEQKSILQPQANVSEVTETPKATSKLNTTPTKLYTQKPVRQPSDEKLAVTKSIHQDKGAPSSTNTIQEEEYVMAVAAEIKNLETKAGMASDEEIERLLKQAEKDITKQRLQKGNTMTVSAQSLLQDVEADLDHSFRSKVFDALISSYKTVRTAVAERND</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLC0</accession>
    <name>A0A5C6ZLC0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">M28 family peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_03565</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003137">
        <property type="entry name" value="PA_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="PTHR12147"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02225">
        <property type="entry name" value="PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022674064" evidence="3">
        <location>
            <begin position="23"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="domain" description="PA" evidence="4">
        <location>
            <begin position="140"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M28" evidence="5">
        <location>
            <begin position="295"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="176"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="178"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD90455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="526" mass="58674" checksum="8A2695D19FCB083B" modified="2019-11-13" version="1">MKLSLISLASALVLAACGSSNSSTSKENDNKVPADPSVYAQTITSDELKEMLYIYASDEFEGRDTGEPGQKMAVNYLKDQYVAMGVPSAYGGDNYFQNVPLERQKYPEVALSVNNQSFENFEDYIILGNVQTQELDINTIVYAGYGIDAKNYSDYTDLDVKGKVVLVKAGEPKDENGNYVTSGDTKNTKWMNGRQEPASKRDAAMERGAKALIFVNQDLLEQYGPYFKQMQLSNNSGSLSLKEEKEDAAMVFMMVGKKMADAIAPNIMDADEPKTIDTQITVSLTSQSEQVASENVLAFIEGSEKPDEILVISAHLDHEGIKNGKVYNGADDDGSGTVAIVEIAEAFKAAQKDGHGPKRSVLFLHVTGEEKGLLGSKYYTDNDPVFPLKNTIANLNIDMIGRIDPEREGDRNYVYLIGSDKLSTELHNISEEVNNKYTNITLDYKFNDDNDPNRFYYRSDHYNFAKNNIPVIFYFNGTHADYHQPSDTADKIEYDLLENRARLVFYTAWELANRADRIIADKAETE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLC3</accession>
    <name>A0A5C6ZLC3_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Putative pre-16S rRNA nuclease</fullName>
            <ecNumber evidence="2">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ruvX</name>
        <name evidence="4" type="ORF">ESY86_04550</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the YqgF HJR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000967">
        <property type="term" value="P:rRNA 5'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16964">
        <property type="entry name" value="YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00651">
        <property type="entry name" value="Nuclease_YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005227">
        <property type="entry name" value="YqgF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006641">
        <property type="entry name" value="YqgF/RNaseH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037027">
        <property type="entry name" value="YqgF/RNaseH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33317">
        <property type="entry name" value="PTHR33317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03652">
        <property type="entry name" value="RuvX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00732">
        <property type="entry name" value="YqgFc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00250">
        <property type="entry name" value="RNAse_H_YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="YqgFc" evidence="3">
        <location>
            <begin position="2"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD90642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="136" mass="15316" checksum="C91B0559D3A6D635" modified="2019-11-13" version="1">MARLLAIDYGTKRIGIAVTDELQIIASGLTTVATKDIYKFLKTYTSTEQVELFLVGEPKQMNNEASESEVSIAKFLVTLEKTFPKIPIKRVDERFTSKMAFQTMIDSGLNKGQRKNKALVDEISATIILQSYLYNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLE9</accession>
    <name>A0A5C6ZLE9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Divalent metal cation transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_06285</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046873">
        <property type="term" value="F:metal ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001046">
        <property type="entry name" value="NRAMP_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11706">
        <property type="entry name" value="PTHR11706"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01566">
        <property type="entry name" value="Nramp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00447">
        <property type="entry name" value="NATRESASSCMP"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="120"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="154"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="193"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="235"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="280"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="322"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="345"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="379"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD89810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="408" mass="43107" checksum="D404A9D414B4B9C7" modified="2019-11-13" version="1">MIRNWFKNIGPGPLVAAAFIGPGTVTVCTLAGVNFGFALLWAMLLSILATVVLQEMSARLGIVSQKGLSEVIRTEISNPILRTLAILLILAAIVVGNAAYEAGNISGSVLGLETLIGNPTLQIGALKLNALSLSIGVIAFVILYLGNYKILERALISLVIVMSVAFLVTAILTKPDLGLVLEGLFVPKVSSESILTIIALVGTTVVPYNLFLHASLVKEKWTQTSDLKFARKDTIIAVVLGGVVSMCIIISAAAIKDAQVDNAADLAKGLEPFFGNYASYFLSVGLFAAGITSAITAPLAAAYVATGCLGWDSQMTSKGFKAVWMFILVLGVLFSSIGFKSIEIIQFAQVANGLLLPIIAGFLLWIMNKSAVLGKYKNTAIQNVFGILILAIALFLGAKSILKVFELI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLI0</accession>
    <name>A0A5C6ZLI0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">YbbR-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_01010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012505">
        <property type="entry name" value="YbbR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07949">
        <property type="entry name" value="YbbR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="322" mass="36657" checksum="38D369AA20A34E2B" modified="2019-11-13" version="1">MFTSLKKKLSKSIKNRRLHVFGLFLLLSFSIWVFTKFSHTYTETATIKLNYTNLPDHKIIAMDSVPEIKVRVSAFGFRLLSYYFSNQSMNVDLEKDTYIANASYVWLANKAQKQIEERMGASIEVLSVNPDTVRFNFDTLTVKKVPVRLRSSISYALGYNSMDSLRVKPDSIKIIGTVKGVSAIDSIVTQDLKLSNVNSNIQQTVELKLPNADGQLKFSAENVKVSLKVEKFTEGTLEVPVDISNLPEDKQINYFPKTIKVFYYVSLSNYKAITASDFKIDCDFEKATSKNQTFFSPTLTVNNKFIKTAKMKQDKVEYIITE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLI1</accession>
    <name>A0A5C6ZLI1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">FtsX-like permease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_08950</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="282"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="332"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="374"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="18"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="310"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD89497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="409" mass="46366" checksum="875C205462FB1B0A" modified="2019-11-13" version="1">MNIWKISQQNMKAKPLYTFLSVFILALSIALLFGIQQLETSLKYQMENNLGAIDLVIGAKGSPLQLVLSSVLHIDNPTGNILYEDAKKISKNPLIKTAVPIAYGDNYKGYRIVGTTDEFAALYHGKLKKGREPKKAMEVILGHTVAEQENLKIGDTLLSSHGLVENDIDLHSEHLTVVGIYQPTKKVIDRLIVTNLKSVWEVHHHHNNNEEDKKEEDHLQHHENLDEGEEISSLLVSFRSPLALLTLPKRINEHTNMQAALPKYELEKLYQYTGIGFKTISWIAYMILVISCLSIFISLYKMVKERAFDLALLRTYGASNFQLIRMVAYEGLTIGFLAFMLGLLLSKAGLYFLFKMVETQYKQNMLQELPYQQFLQTGALVSIMILISISLAIYPIIKMNISTILSHEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLL3</accession>
    <name>A0A5C6ZLL3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TolC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_03010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the outer membrane factor (OMF) (TC 1.B.17) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015562">
        <property type="term" value="F:efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003423">
        <property type="entry name" value="OMP_efflux"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02321">
        <property type="entry name" value="OEP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022667728" evidence="2">
        <location>
            <begin position="26"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="457" mass="51775" checksum="F9F7BDC98E5B6B12" modified="2019-11-13" version="1">MKNNQSRLSIFFLASLCLVSSSSIAQQLDPVLMDLINKGLNKSHSVQIQNYNAEQAQIDQKLAKSVFLPKLTLNGSYTRLDDDITFDDDTQNLLIGTQRLLVKEAAGIPFNSAFPAGIPLEPVPNLQNKDILRSSMDMDWVLFSGFEASNALKASRHKEASINYLAMAEKDEIALKIIENYDKLALVYASKRVLTTSENYLNEQAYYMKKAIENGLATPIGRKKIELAKQQLAGKLLDFNHNKTLLIEVLHQLTNETKENLVLLNPQLQPFTTDSLSTAEKRNELKALEEAERATLYKSRMEKSKVIPKLAVQGHYEFIEDDLSLLDPKWYVGVGIKWNLFDGNQSRLESKKSLIEGQKYREQIEDANEMIALSIIKAELGYEASLQNTEIILKEIELASDTYNMIDKQYKNNLASLNDVLDALNDLEKSNFKLQQSYFDQRRAITALLHAKGILNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLM2</accession>
    <name>A0A5C6ZLM2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">OsmC family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_04195</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003718">
        <property type="entry name" value="OsmC/Ohr_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036102">
        <property type="entry name" value="OsmC/Ohrsf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02566">
        <property type="entry name" value="OsmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82784">
        <property type="entry name" value="SSF82784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="133" mass="14778" checksum="2874146A12D7E626" modified="2019-11-13" version="1">MTSKVTYLGNLRTESEHLKSGSTFFTDAPSDNNGKGEAFSPTDTVATGLASCMLTIMGIKCKAMHLDMEGTIAEVTKTMATNPRRISKIDVIFTLPFEADEKTRKILEHSAITCPVYYSLHPDIEKNIVFKWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLP5</accession>
    <name>A0A5C6ZLP5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_04350</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="216" mass="25342" checksum="CF82E1D71F76F1FB" modified="2019-11-13" version="1">MEFVGHIVLNTPFPCHGSCLNKKIEIIIGQHVGHLYMPILRNDIEKESLPFLSEPFPQSTVKFNQEVNWGRLVDSGNNISSVETLKFVFNIKDVNFLNNQDKFIIETDRWLKKFEENLFPLYWILNLGTIRVAGEMNNNFTYYYKNNEAKSQNLYQKHSGTKIIITTQEKDGLNLKLLKKIVRLSNQNKEISIDYRLLRDAHKCFLAGDYRSQYYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM20</accession>
    <name>A0A5C6ZM20_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Beta-lactamase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase" evidence="1">
        <location>
            <begin position="42"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="372" mass="42646" checksum="A558B49D2BB7D739" modified="2019-11-13" version="1">MVATHLETVAATAIKPQSKEKSPILIERYPENTTKGVRHKLDSLLQRINERHDFHGAILVAKNNKVLYNNQIGYADFNKKTPLHEESAFQLASVSKQFTAAAIMLLNERNQIKLTDTVNAYFPDFPYADVTIENLLNHTGGLPKYFWVAEHKWQQEKAPINSEMMALLESSNVQRFFKPGRTFDYSNTGYIVLASIVEKVSGTSFSSFLKSNIFEPLEMKHSYVYSFENDSIKENQLDGYRLYRGWRHLKIRGTVNDAIVGDKNVYTTTEDLFKWTLGLNTGKLLTKASLDLMYSEGETVHGRKIPYGFGFRIDTKEKNRIYHHGRWNGFGTGLTKYLEDDLVVIVLEHTSYKAIRSLNEKIKDIVTEHFGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM76</accession>
    <name>A0A5C6ZM76_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MarR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03790</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01047">
        <property type="entry name" value="MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="151" mass="17288" checksum="175A5897266526F9" modified="2019-11-13" version="1">MKDKTIDYVLRTTWLAVNKMYNEEAAEFDTTMATGFALLSIDPEKGTPSTSLGPKMGMEATSLSRTLKTMQEKGLIERKPNPEDGRGVLIYLTEFGREKREYSKEKVLTFNETIKDHVSAEELAHFFKVSEVINNMISNKQIYNKKEQILK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMB8</accession>
    <name>A0A5C6ZMB8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_04045</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="62" mass="7299" checksum="083BA0A50AB0D4D3" modified="2019-11-13" version="1">MTKISGTVGFEVLRQELFQDDFVIAVIDGRSKRSEEKSNPFKYRMNLIFSAKNFSLWMCCVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMI0</accession>
    <name>A0A5C6ZMI0_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">CRISPR-associated endonuclease Cas9</fullName>
            <ecNumber evidence="8">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8 12" type="primary">cas9</name>
        <name evidence="12" type="ORF">ESY86_02655</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9/crRNA/tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer; Cas9 is inactive in the absence of the 2 guide RNAs (gRNA). Cas9 recognizes the protospacer adjacent motif (PAM) in the CRISPR repeat sequences to help distinguish self versus nonself, as targets within the bacterial CRISPR locus do not have PAMs. PAM recognition is also required for catalytic activity.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="8">Monomer. Binds crRNA and tracrRNA.</text>
    </comment>
    <comment type="domain">
        <text evidence="8">Has 2 endonuclease domains. The discontinuous RuvC-like domain cleaves the target DNA noncomplementary to crRNA while the HNH nuclease domain cleaves the target DNA complementary to crRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the CRISPR-associated Cas9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="8"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043571">
        <property type="term" value="P:maintenance of CRISPR repeat elements"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01480">
        <property type="entry name" value="Cas9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028629">
        <property type="entry name" value="Cas9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033114">
        <property type="entry name" value="HNH_CAS9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041383">
        <property type="entry name" value="RuvC_III"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13395">
        <property type="entry name" value="HNH_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18541">
        <property type="entry name" value="RuvC_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01865">
        <property type="entry name" value="cas_Csn1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51749">
        <property type="entry name" value="HNH_CAS9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 8 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8 9 12" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3 8 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 9" id="KW-0540">Nuclease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="HNH Cas9-type" evidence="11">
        <location>
            <begin position="579"/>
            <end position="734"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="576"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="active site" description="For RuvC-like nuclease domain" evidence="8">
        <location>
            <position position="8"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor for HNH nuclease domain" evidence="8">
        <location>
            <position position="650"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TXD90878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1134" mass="131980" checksum="ADD49536BC307FFF" modified="2019-11-13" version="1">MARILGLDLGTNSIGWALIDDEKKEILGIGSRIFPEGVVNLGEGEGRETSKNASRTEDRGVRRQFFRRRLRKRYLLRELAKHDMCPIDYNMVKVWNQKEIFSNKNLQEWLRLNPYQLRAKAINEEVSLDELGRIFYHMIQRRGFQSNSRSAGAETNEKSVIFKGDAKAGKIGIAETANSIEDHQTLGSYLNQIYPKENAPFTDELERIRNRYTTRQMYIDEFEAIWEHQKQYHSELTDELKTIYGGRKKDGFPEDGVLFHQRPLRSQKHLVGNCSLEPKKTKCQISAIPNEQRRIYEWLNTLKCDLAGEKVKINSEEREKILDLLFSKEKVKFKEIRKAIGKLDGHYQFNYKDDDAIYGSHTISNLSNKKFFGKAWFDFSDKEQEDIWHVLYSFDDRDKLKAYALERWEFNEEKAEKISKFNLKDGYANLSRKAISNMLPFLKLGFTYDIAVALGGVKNALGIKWEPQEDFMLNNVPEIVRSNLEGGYIAHLKEMLKKESQLSDKELAKLYHHSSNIEITKLLDRLPVNPEADKEIQSIKNPVVITALFEIRKLVNEIIDDYGKPDEIKVELARDLKISKSKRNDIRKEQQRLERENDRVKAELDYIGQRPTHVNILKYKLWEECNRTCPYTGRNIEVNQLFSGEVQIEHIYPWSRSLNDSFMNKTLCFVDENGAKGDLTPFEFYGKLGEQKWEAIKLQALSCFKNKAHYPSAYFKFKQFVKQKHDSDFISRQLNDTRYISKEANNYLSKICSKVMVAPGQMTSNLRHHWGLNSVLNLEDDTKTRDDHRHHAIDALVMACSTRGHLQELSKWNRYDRSYDLNNFPKPWESFREDAEKAVDGILVSHKKSKSILTVRKHITEKNGERYTNKGVAARGQLHKETVFAKRQAPNSDEAFHVRKPIDSLTTEKQLEKVVDITIKQLIFKRINVLGGFVKGKIPLETFFTVDENGNKQPQIFLPNKNGNPVPVLKVRMRENIGGAEQLKDDLNQWVNPRNNHHVLIYKDDEGNLKEDVVTFWTVVERKSKGFPVYQLPPDGIEIITAMQINDMFLLGLNEDEIDWENLDYVFLNDYLFKVQTLSSNFYEFRLNRDATQIKDTNSNVFRRIQSFGKGKTGWLTFNPIKVKVSVSGKIVKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMS7</accession>
    <name>A0A5C6ZMS7_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6 7">DNA replication and repair protein RecF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">recF</name>
        <name evidence="9" type="ORF">ESY86_00690</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the RecF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00365">
        <property type="entry name" value="RecF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001238">
        <property type="entry name" value="DNA-binding_RecF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018078">
        <property type="entry name" value="DNA-binding_RecF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042174">
        <property type="entry name" value="RecF_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32182:SF0">
        <property type="entry name" value="PTHR32182:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00611">
        <property type="entry name" value="recf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00617">
        <property type="entry name" value="RECF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00618">
        <property type="entry name" value="RECF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 7" id="KW-0235">DNA replication</keyword>
    <keyword evidence="6 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="SMC_N" evidence="8">
        <location>
            <begin position="3"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="30"/>
            <end position="37"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD91139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="359" mass="41310" checksum="59BA1D34E42BDF0C" modified="2019-11-13" version="1">MILKALSLVNYKNFESQDFEFDDKINCFVGANGVGKTNALDAIYHLSFGKSYFNPIASQNINHDAEFFVVDGIFEKHEKTEKIIVSLKRGQKKMIKRNAKAYEKFSDHIGFVPLVIISPADRDLIIEGSETRRKFIDSVISQSDKAYLNNLISYNKVVAQRNALLKYFALNNTFNAQTLEIYNEQLDSYGAEIFNTRREFLETFIPIFKARYKAISNDNEAVNLVYKSDLHEQRLKDLLVQNLNKDKALHYTSVGTHKDDLVFEIETYPIKKFGSQGQQKSFLIALKLAQFDFIKAQSGVTPLLLLDDIFDKLDENRVAQIIGLVDDDNFGQLFISDTHPERTEQVIKQIHQSYKMFKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN04</accession>
    <name>A0A5C6ZN04_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Bifunctional protein FolD</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="8">Methylenetetrahydrofolate dehydrogenase</fullName>
                <ecNumber evidence="8">1.5.1.5</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="8">Methenyltetrahydrofolate cyclohydrolase</fullName>
                <ecNumber evidence="8">3.5.4.9</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="8" type="primary">folD</name>
        <name evidence="11" type="ORF">ESY86_04720</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NADP(+) = 5,10-methenyltetrahydrofolate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:22812"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57455"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.5.1.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>5,10-methenyltetrahydrofolate + H2O = (6S)-10-formyltetrahydrofolate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:57455"/>
            <dbReference type="EC" id="3.5.4.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.5" evidence="8"/>
    <dbReference type="EC" id="3.5.4.9" evidence="8"/>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004477">
        <property type="term" value="F:methenyltetrahydrofolate cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004488">
        <property type="term" value="F:methylenetetrahydrofolate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006164">
        <property type="term" value="P:purine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01080">
        <property type="entry name" value="NAD_bind_m-THF_DH_Cyclohyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01576">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000672">
        <property type="entry name" value="THF_DH/CycHdrlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020630">
        <property type="entry name" value="THF_DH/CycHdrlase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020867">
        <property type="entry name" value="THF_DH/CycHdrlase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020631">
        <property type="entry name" value="THF_DH/CycHdrlase_NAD-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00763">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02882">
        <property type="entry name" value="THF_DHG_CYH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00085">
        <property type="entry name" value="THFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00766">
        <property type="entry name" value="THF_DHG_CYH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00767">
        <property type="entry name" value="THF_DHG_CYH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="3 8 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 8" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="4 8" id="KW-0521">NADP</keyword>
    <keyword evidence="1 8" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="5 8 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 8" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="THF_DHG_CYH" evidence="9">
        <location>
            <begin position="4"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="THF_DHG_CYH_C" evidence="10">
        <location>
            <begin position="122"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="164"/>
            <end position="166"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD90060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="291" mass="31701" checksum="3B73DF2C30EF6748" modified="2019-11-13" version="1">MTILDGKKVSNDIKDEIKAQVDKMIAKGEKVPHLAAVIVGNDGASLTYVGSKVRACERVGFESTMVRLSNTTSEIELLDKIEELNKNDDIDGFIIQLPLPEQINTQKVLMAVDPSKDVDGFHPENFGKMALDMTTFIPATPFGILELLDRYGVETKGKHTVVIGRSHIVGRPMSILMGRKGFPGNSTVTLTHSHTKNITQITSQADIIISALGVPNFLKAEMVKDDVVIIDVGITRVPDDSTSKGYRITGDVDFENVSKKASYITPVPGGVGPMTIAMLLKNTLLAREQRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN06</accession>
    <name>A0A5C6ZN06_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Gliding motility-associated ABC transporter substrate-binding protein GldG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">gldG</name>
        <name evidence="3" type="ORF">ESY86_01180</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019196">
        <property type="entry name" value="ABC_transp_unknown"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019863">
        <property type="entry name" value="Motility-assoc_ABC-rel_GldG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09822">
        <property type="entry name" value="ABC_transp_aux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03521">
        <property type="entry name" value="GldG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="531"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="domain" description="ABC_transp_aux" evidence="2">
        <location>
            <begin position="32"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD91229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="558" mass="63062" checksum="3ACB9C335A92A01D" modified="2019-11-13" version="1">MTTRTKNTLLTIGITLIAIIAVNLISNTVYKRFDLTTDKRYTLSQAALTTVDEVNSPLIIDVFLEGDFPSEFRRLRDETRQIIEEFALYNSNVKFSFINPLKEESSRDQNLQQLSQRGLQPFQVNIKESGKTSQELIIPWALASYNEQTVVVPLIKNKIGATDQDLVNASIQNLEFVFADAFKKLTTPKKKKIAVLRGNGQLKDIYVADFLKTLGEHYFLAPFTLDSIAASPQNTLKALEDFDLLISAKPNDPFSEAEKYALDQYTMNGGKSLWLTESVVMDKDSLLNNGGRSVAIMKDLNLNDFFFKYGVRVNPVIVNDLYSAPITLAVGEGNNTQFQPVQWPYSPLAASNPNHPITTNLDPVKFDFASQIDTLKNEVTKTILLRSSQLTKLDGVPTEINLDMVKQEPDPSRYTKPNQSLAVLLEGRFTSVYKNRVKPFEISEDKTESEPTKMIVIADGDVIKNDVVRNKPQELGFDFLTKRKFGNKEFLMNAVNYLLNDDGLINIRTKEVKLAFLDANKVADEKTKWQLINIVLPLVILAAFGLIFNFLRKRRYSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN63</accession>
    <name>A0A5C6ZN63_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nuclear transport factor 2 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03395</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12680">
        <property type="entry name" value="SnoaL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="7"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="155" mass="18260" checksum="6353F4A96B9D4C61" modified="2019-11-13" version="1">MKQLLINFYEAFQRLDAEAMVACYHPDVVFEDPAFGVLHGNRANNMWRMLCKSQESKDFKLTYSSVEANQNTGSVLWESFYTFSKTNKKVHNVIQAQFKFKDGKIIEHIDEFDLYDWSKQAFGARGRILGKTLFFKNKLKHRANFLLTNFENKQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN93</accession>
    <name>A0A5C6ZN93_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Biotin/lipoyl-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_03015</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039562">
        <property type="entry name" value="MFP_biotin_lipoyl_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13533">
        <property type="entry name" value="Biotin_lipoyl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022705667" evidence="2">
        <location>
            <begin position="22"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="Biotin_lipoyl_2" evidence="3">
        <location>
            <begin position="35"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="140"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD90940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="319" mass="34945" checksum="4A29C837F7EE393C" modified="2019-11-13" version="1">MKSIKNIIILSILMLAVSSCGNDTITEYRGKVKFETISVSGKLAGRISEIYVGEGQSVKKGDTLAYVDIPEVNAKMMQAEGAITSAKGQLNMAYKGATADQINQIDGQIDASNAQLNFAQGSYNRLQAMYKDSLVTLQQFDEVKMKLNMAKAQVASLEAKRKEVSNSARIEQIEQAKGQLDQAVGAKKEVLSAENEQYLIAPAAMSIETISLQEGELLTPGYALFNGYEKGSVYFRFTVPESKVYDFEVGKTITLVNPYTDQVTEGKITTIKQLANYADITSTAPLYNLSESIYELKIVPTSTEANQSFFLNATILIKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNB0</accession>
    <name>A0A5C6ZNB0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Septum formation initiator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_00580</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007060">
        <property type="entry name" value="FtsL/DivIC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04977">
        <property type="entry name" value="DivIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="101" mass="12153" checksum="AED81592CA62184D" modified="2019-11-13" version="1">MFKYLKNIFVLIFICFAIWMLFFDANSLIIHSELNSEISDLEDQKVYYGNEIIKDKKAIKQLSTDEGIEKMAREKYYMKKENEDIYIIEYEDSLKLETQDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNF6</accession>
    <name>A0A5C6ZNF6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03975</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="268" mass="30889" checksum="356E0098EDC2E074" modified="2019-11-13" version="1">MKLKIILIVLSLVFAACKDANSERKPVGNEQPSEVKSTRPSLNYPENLSKVFEAHGGIGTWNAMNTLKFTMDKEGGDEITTTDLKNRKSLIQMPKHHIGFDGENVWLQKADTTSYKGNPKFYYNLMFYFYAMPFVLGDDGIIYENIAPLQFEGKSYPGIKISYKAGVGESPEDNYVMYYDSETYQMAWLGYTVTFFTNEKEEAYHFIKYRDWQTLNGLTLPKTLTWYNYENNLPTTKQRDLEFSDVLISEEKMDDSMFNLPEGAEVVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZP47</accession>
    <name>A0A5C6ZP47_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">3-isopropylmalate dehydrogenase</fullName>
            <ecNumber evidence="13">1.1.1.85</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">3-IPM-DH</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Beta-IPM dehydrogenase</fullName>
            <shortName evidence="13">IMDH</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13 16" type="primary">leuB</name>
        <name evidence="16" type="ORF">ESY86_02215</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 14">Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13 14">
            <text>(2R,3S)-3-isopropylmalate + NAD(+) = 4-methyl-2-oxopentanoate + CO2 + NADH</text>
            <dbReference type="Rhea" id="RHEA:32271"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17865"/>
            <dbReference type="ChEBI" id="CHEBI:35121"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.85"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13 14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="13 14">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="13 14">Binds 1 Mg(2+) or Mn(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 13 14">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 13 14">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.85" evidence="13"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00072"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003862">
        <property type="term" value="F:3-isopropylmalate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01033">
        <property type="entry name" value="LeuB_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004429">
        <property type="entry name" value="Isopropylmalate_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42979">
        <property type="entry name" value="PTHR42979"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00169">
        <property type="entry name" value="leuB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="12 13 14" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 13 14" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="9 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13" id="KW-0464">Manganese</keyword>
    <keyword evidence="8 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 13 14" id="KW-0520">NAD</keyword>
    <keyword evidence="10 13 16" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Iso_dh" evidence="15">
        <location>
            <begin position="4"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="221"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="249"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="13">
        <location>
            <position position="142"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="13">
        <location>
            <position position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="TXD90796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="372" mass="41219" checksum="5975A18500E2138F" modified="2019-11-13" version="1">MKLKIAVLPGDGIGPEVTKEAIKVLKAIAQEFDHSFQFKYASVGAVAIEKFNDPLPKKTLDLCKSTDAILFGAIGDPRFDNDPSAKIRPEQGLLRLRKALGLFANVRPVKAYDTLLAKSPLKRDIIKGTDICIYRELTGGIYFGEKTLSDDGNHATDLCDYTREEIERVTHLAFKAAQSRKQKVTLVDKANVLETSRLWRKVVTEIAAEYKDVKLEFLFVDNAAMQIILNPKQFDVILTENMFGDIISDEASVIGGSIGLLASASVGEKYAMFEPIHGSYPQAKNLGIANPIASILSAAMLLDHFKLFEEAELIREGVERSLKLNITTPDLNTKYEHISTSKVGDFIEDFINNPKDNNMNFANIHLGQSTII</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPF0</accession>
    <name>A0A5C6ZPF0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_01565</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="132" mass="15032" checksum="97E39536331EE86F" modified="2019-11-13" version="1">MDEQYYLNMNPDQVSDFVNSASGKPVVMLNIVKYKVLVSETGMTGKESYKEYMRQATPFFLKANAEIVFYGSPKHMLIGPEAHTLWDDVLIVKYNSVSDFMSMIMAEGYPSHLREQALADSRLIHCTPNKNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZQT6</accession>
    <name>A0A5C6ZQT6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Endonuclease/exonuclease/phosphatase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_01310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endo/exonuclease/phosphatase" evidence="1">
        <location>
            <begin position="28"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="280" mass="31852" checksum="3BA5624E82A5D40C" modified="2019-11-13" version="1">MDMKLPILLIIALTCAITSCKSQDMKIMSYNIRLDIASDGENAWPNRKDFLSSQVLFLEPDILGLQEVRPSQIEDLNNALTNYSYIGTGRDGGNEGEHTSIYYNTDKVKVENENTFWLSETPEKKSMGWDAAYPRICTYGLFTYRESKQKIWVFNTHLDHVGAEAQLEGIKLVLQKIESVNTKNYPVILMGDFNTEPGSDVYTETSKLLTDSKPLAELRFGPDGTFNGFKYDQPVTRRIDFIFISKNSDVAVVKYAVFSDAIDFKYPSDHFPVFVTLEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZR20</accession>
    <name>A0A5C6ZR20_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Response regulator transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_00110</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007492">
        <property type="entry name" value="LytTR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04397">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00850">
        <property type="entry name" value="LytTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50930">
        <property type="entry name" value="HTH_LYTTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="4"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="HTH LytTR-type" evidence="3">
        <location>
            <begin position="145"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD91040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="231" mass="26589" checksum="543AB256BC349F2C" modified="2019-11-13" version="1">MTLNCVVVDDSAIQRLSIVKLIENHSSLNLIAEYSSALETKNGLNTHKVDLIFLDIEMPVLNGFELLDVLNNKPQIIFVTGKTEYAFKAFNYDATDYLQKPITRERFNQAVEKALEQHKLKLDFNETDGEHIFVKSNLKKRKVYIKDIKWIEALGDYVKLVTEENSLVVLSTMKAFEHELPEGKFLRIHKSYIVNLDKVDRFNSKNVEVGAYEIPLSRNKKTQLVDALNNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-02-10" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZRN8</accession>
    <name>A0A5C6ZRN8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NAD-dependent succinate-semialdehyde dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_01295</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004030">
        <property type="term" value="F:aldehyde dehydrogenase [NAD(P)+] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07100">
        <property type="entry name" value="ALDH_SSADH1_GabD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044148">
        <property type="entry name" value="ALDH_GabD1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="4">
        <location>
            <begin position="4"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD91250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="454" mass="50711" checksum="8A4D815B082933A7" modified="2019-11-13" version="1">MSNKTSTHNPFTGESIKTYNLHTDVQVESMLQLANDVSKTWRQKPIKERSKLLNKVAKILSDNLETYSELMTAEMGKPIAQSRSEIEKCIFLCDFYRKNADSFLADQIIETDAKESFISYDPLGTILAVMPWNYPFWQVMRFAIPTLTAGNTALLKHASNVTGCALIIEELFEKAGYPKGCFQTLLVNHDQVEQILSDDRVKAVSLTGSEKAGRKIAEIAGRNLKKAVLELGGNNACVVLGDANLEAYLDIMVNARMQNTGQSCIAAKRFIVEASIYDEFLEKFTKKVKSLKHGDPTDDQTDFSVLARADLADILEDQVERSLKKGAKVHFGNERKKAYYQPTIITNVTPNMPIFDEETFGPVAAIIKVKDKAEAYEMVANTRFGLGTMIFTEDFEDATAHVSEIEDGAFFINELVKSDPRLPFGGTKASGYGRELSEEGIMEFVNKKTVYINH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZRQ7</accession>
    <name>A0A5C6ZRQ7_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein-glutamate O-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.80</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">ESY86_01395</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-glutamyl-[protein] + S-adenosyl-L-methionine = [protein]-L-glutamate 5-O-methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:24452"/>
            <dbReference type="Rhea" id="RHEA-COMP:10208"/>
            <dbReference type="Rhea" id="RHEA-COMP:10311"/>
            <dbReference type="ChEBI" id="CHEBI:29973"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:82795"/>
            <dbReference type="EC" id="2.1.1.80"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.80" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000156">
        <property type="term" value="F:phosphorelay response regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008984">
        <property type="term" value="F:protein-glutamate methylesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.155.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035909">
        <property type="entry name" value="CheB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022642">
        <property type="entry name" value="CheR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000780">
        <property type="entry name" value="CheR_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022641">
        <property type="entry name" value="CheR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036804">
        <property type="entry name" value="CheR_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000673">
        <property type="entry name" value="Sig_transdc_resp-reg_Me-estase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01339">
        <property type="entry name" value="CheB_methylest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01739">
        <property type="entry name" value="CheR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03705">
        <property type="entry name" value="CheR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00996">
        <property type="entry name" value="CHERMTFRASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00138">
        <property type="entry name" value="MeTrc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52738">
        <property type="entry name" value="SSF52738"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50122">
        <property type="entry name" value="CHEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50123">
        <property type="entry name" value="CHER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CheB-type methylesterase" evidence="10">
        <location>
            <begin position="12"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="CheR-type methyltransferase" evidence="11">
        <location>
            <begin position="219"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="9">
        <location>
            <begin position="1226"/>
            <end position="1279"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="1308"/>
            <end position="1536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="650"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="695"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="695"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="26"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TXD91270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1537" mass="174257" checksum="CFE3E4D0EDBC8044" modified="2019-11-13" version="1">MATAKNNKVQPPATKQNFPIVGIGASAGGLDAFKKLLSAIPESSGMAYVLVQHLDPSHESMLPEILQRVTKIPVHEITEDMHLAPEHIYIIPSNKILTSTDGVLQLAPRDKKILNLSIDIFFTSLAEVHKEFAIGVILSGTGKDGTEGLKAIKEHGGISIAQDMESAAYDGMPESAINAGVVDFILAPEKIPEQLLQINSAYKTSRVFTKEKPPTKDEEAVFEQIISQLRQSSGVDFTHYKDPTLRRRIARRLAIAKEKNMADYLKFLRSDKDEQDALFQDMLIPVTSFFRDPKTFQALTETVFPSILKHKNPDAPIRMWIAGCSTGEEVYSIAICLQEFLGANSDSYRDRTKIQIFASDISEKAIKKARAGIYTTADVEGLSASQLETYFTKNNGGYEVSKSIRDMCVIAPHNFLKDPPFAKIDLICCRNVLIYMDSFLQQKAFATFHYALKENGFLLLGKSESVGASSDLFAQVVKKEKIYSRKRVAGRFRRGATELKEEVSTRKIKNQTKQEATQTDFKKSAEAIMIAKAPASVVVNEQLDIVHIHGDISPFLETPQGQPTHHLLSMARDGLSFELRNAIHKASKDKIAVTTEHIPLKINAPVTNSNSDREGQGKQTLVVMEIIPMNDTVERHYLIRFEKTIVANVKDEKSASSGKTKAAEALKRNKQLEKELEHNREDMRAITQDMEAANEELQSANEELQSSNEEMQSLNEELETSKEELQSTNEELIIINRELFENQEQLSAARLYSDSIVSTMRHPLIVLDKNLLIKTANAAFYEKFKVDEKEIEKKWFYEIQHRQFDDVKLRSLLVKVLSQRNRIDDFEIVLKLPKLGARTLSLNARQVNNENTDEQLILLAIEDVTEQVAAQKIIDDNKKRTEKERKLLHDFFTQAPAVLAILKGPEHVFEFANEAYMEFVGNRNLKDRSVLDALPETAGQGFIELLDTVYKTGETYNGKELSLKLDKGTGEFQQFYMNFIYQALRNDKDEIEGILVYAHDVTEQVMARKLIEASEKRFSNILEQSIMAIGILKGTDMVISFANAPLLETWGKGDDVFGKPFFEVMPEIKDQGFPELLDQVYTTGVPYYGHETEVTHIRNGKEETRYYNFVYQPYTEVDNSITGITILATDVTEQVLAKKQIEESENEQLMLARLLKLATDSAAVGIWSLDVDSSKLKWSNIHKKLWGYDEHREDLTYQDWHSVIVPKDKKMAFQKIEASKENHDIYEVDYRITRANDGAVVWMRSTGQYHYDEFGKAHTLSGISIDITEHKSFTEALEVKVKQRTAALKKSNEELKKTNTQLDQFAHVASHDLQEPLRKILTFSMRLQDDHKAELSKEVKFYLDKIEGASARMSTLIRELLNYSRLLGHEKSVVQTNLNATLKNVLKDFELLVEEKKALINFDELPSIEAIPLQMNQLFYNLISNALKFSREEVPPVINITSRTLSDKQVKKHPTLNPSVTYVEIRFKDNGIGFDQKYSEKIFTIFQRLHNRDTFIGTGIGLALIKKITENHQGLTFAAAKEHKGATFHVILPVKQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZRU9</accession>
    <name>A0A5C6ZRU9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytosine-specific methyltransferase</fullName>
            <ecNumber evidence="8">2.1.1.37</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">dcm</name>
        <name evidence="9" type="ORF">ESY86_01630</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = a 5-methyl-2'-deoxycytidine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:13681"/>
            <dbReference type="Rhea" id="RHEA-COMP:11369"/>
            <dbReference type="Rhea" id="RHEA-COMP:11370"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:85452"/>
            <dbReference type="ChEBI" id="CHEBI:85454"/>
            <dbReference type="EC" id="2.1.1.37"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.37" evidence="8"/>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003886">
        <property type="term" value="F:DNA (cytosine-5-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018117">
        <property type="entry name" value="C5_DNA_meth_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001525">
        <property type="entry name" value="C5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031303">
        <property type="entry name" value="C5_meth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00145">
        <property type="entry name" value="DNA_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00105">
        <property type="entry name" value="C5METTRFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00675">
        <property type="entry name" value="dcm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00094">
        <property type="entry name" value="C5_MTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00095">
        <property type="entry name" value="C5_MTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51679">
        <property type="entry name" value="SAM_MT_C5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0680">Restriction system</keyword>
    <keyword evidence="4 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6 8" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="6">
        <location>
            <position position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD91310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="332" mass="37578" checksum="8E2C0AE0D895F91C" modified="2019-11-13" version="1">MTQKPKYIDLFSGAGGFSLGFDSQGFEQVFSVDIEPNFCKTYTHNFPEHLLIEKDICELSDAEIDALKEFDNIDVIIGGPPCQGFSIAGNIGRKFVDDPRNRLFTEFVRVVKVVKPKFFVMENVARLYTHNQGETRQEIIRDFEKLGYHVACEILNSADYGVPQVRKRAIFIGRLHEQSIEFPAKEVANYVSVKQALSHYPKLESGETSSVPNHIAMSHSDQMLNKMSYVTDGGDRNEIPVKIRPKSGDVRKYIKYASDKPSVCVTGDMRKIFHYDQNRALTVRELAKLQSFPDDFVFKGTRISQQQQVGNSVPPKMAEAIAKVILKMRGNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6Z9Y5</accession>
    <name>A0A5C6Z9Y5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_20430</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000072">
        <property type="protein sequence ID" value="TXD86293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="176" mass="20811" checksum="4D089D2D4ED2181C" modified="2019-11-13" version="1">METWNELIQFVRKLPYGRNANRTDFELVIKEKKGSCSSKHALLKKVADLNNIKNVKLILGIYKMNRQNTPNIGNVLIENSIEFIPEAHCYLKIDDRRADITTDNSDFEKIERDILNELEIEPEQVAEFKVEYHKEILTKWISENRIDRDFNEIWKIREKCITNLTEKPTHNTVYSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZA33</accession>
    <name>A0A5C6ZA33_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_20790</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000128">
        <property type="protein sequence ID" value="TXD85798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008490">
        <property type="entry name" value="Transposase_InsH_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05598">
        <property type="entry name" value="DUF772"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF772" evidence="2">
        <location>
            <begin position="44"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="161"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD85798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="256" mass="29758" checksum="CC0C1B8B2D81F2BD" modified="2019-11-13" version="1" fragment="single">QTCLFPVSLEDSIDQFNSVRAIDQFVEQLDLEKLGFRRDFIENGPPAYRPSVLLKLYIYGYMNRVRSSRQLEKECRRNIEVMWLLESLAPDHNTISNFRKDNAKAIKKVFFATVQIARNFGLIGATLIAGDSTKFRAQNSKKNNFNQKKIQRHLDYIDNKLAQYNKALDQGENDQENEQIKKDVEKHKRRRKQYEQLEKQLQESGDTQISTSDPESRHIIIRGNITEVAYCVQSTVDADHNIPIDYLVTNKNDSKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAF0</accession>
    <name>A0A5C6ZAF0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF1963 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_20765</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000122">
        <property type="protein sequence ID" value="TXD85840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015315">
        <property type="entry name" value="DUF1963"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035948">
        <property type="entry name" value="YwqG-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09234">
        <property type="entry name" value="DUF1963"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103032">
        <property type="entry name" value="SSF103032"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD85840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="275" mass="32177" checksum="2F7B80D4B78664F0" modified="2019-11-13" version="1">MRTKQEYLEFLNKIKWEKGKEIESYLIPAIDIKVEESQSESNIGSSKFGGNPDLPAKTDWPICDNEPMTFLAQINLQQISEFDLENILPKSGILYFFIANPSEFSLEHKVIYSVDNEISRRDFPKGLNKDCRFSQLKMLFENIYTFPSGETLEIESLSENDKESTFELLELDEDFFTYENNQILGHTYPVQGDVNLEWACRILGVEVSFKSFEQNQEKIDNLRNDFINILQFSAENSIPEFWDNFYIDSMGYFGIRKQDLKNREFDNTVLTFQNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAW2</accession>
    <name>A0A5C6ZAW2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000134">
        <property type="protein sequence ID" value="TXD85745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023099376" evidence="1">
        <location>
            <begin position="23"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD85745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="155" mass="18297" checksum="8D0E115B30996092" modified="2019-11-13" version="1" fragment="single">MKRNFKYILIILTFGLFQNLLAQENKVGKVKVVKYRDTSDRFTESTTDSTLAYLNKREHDILITNKKDTTRLKTNSLGIFEIPKKYFNYCSINVNPKTKDLREEFLFMEGLGKKDSLEFEVYDYHFSNKIDSTKAPEFYNKFNTQRAEQDFLAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZB28</accession>
    <name>A0A5C6ZB28_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_20555</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000087">
        <property type="protein sequence ID" value="TXD86170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022829034" evidence="2">
        <location>
            <begin position="20"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="214"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="331" mass="38873" checksum="11E9808BA18D40BF" modified="2019-11-13" version="1">MKKISFVILTLVFNSMLSAQNDDFGKFPSENNVEKPMLTSDLLKSLNWKKLKEFSNSNQGHYAYERKDSLLTEYEYVQQGRVANFELTSFNGKVLEYHSQISNTSKETNTNYFDKEVWLEYAHKYLPNLPDSLKLTVAESKDVLKAYYELIGVGTRDEYGWICEYSTVGMATQRRQATMQLIRYQRRDLLEQVVNYPNVQVQLYITDALIYDDLQKKEYIEENLKAELTQMTEELDSLKSKKITDWRIESLNYRISDSNEYIEQLESELLSDNDWKRIYALRDSNQQVKTCKSGTGSYKTYENTTDELLSESAILEIPKRYSELESLGYFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBJ1</accession>
    <name>A0A5C6ZBJ1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Biotin/lipoyl-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_19165</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000037">
        <property type="protein sequence ID" value="TXD86814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039562">
        <property type="entry name" value="MFP_biotin_lipoyl_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13533">
        <property type="entry name" value="Biotin_lipoyl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="domain" description="Biotin_lipoyl_2" evidence="2">
        <location>
            <begin position="72"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="450" mass="50832" checksum="4FE9BDDD664AC836" modified="2019-11-13" version="1">MLNISHNQLNKKVSLEMYSAYAKAHHSEYYKYFNRFLFTFALIGIIVLFLPWTQNVSGTGYVTTLSPEQRPQTIQSPIPGRIEQWFINEGDYVAKGDTILFISEIKNEYQDPRLVERTVAQRDAKSNAVVAYKGKVQALGNQIYALQNERVFKKEQAENKLKQARYKVQSDSIDLVAAETNREIAKRQYERTATLQAEGLKSKADVEDKSLKLQETDAKLIGQENKLLASLNEQINARIDIDRIATEYEEKISKAQSEKFTASSSQFDTEAQVSKLENTSANYEMRDKMVYILAPQNGYINRAIISGIGETFKEGQELVGIMPSDYDLAVETFVAPIDLPLIHVGEDIRVEFDGWPAIVFSGWPNASLGTYGGIVVAVETFISPNGKFRVLIAPNQEEQWPKNVRVGSGARTIALLQDVPIWYELWRQLNGFPPDYYAAGGADNSKRKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBQ2</accession>
    <name>A0A5C6ZBQ2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_20240</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000061">
        <property type="protein sequence ID" value="TXD86427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="236" mass="27118" checksum="70E71B2DD7AC06BD" modified="2019-11-13" version="1">MRKTLLIGIGIALLTFACGTPLSTVRTVKFSPKNDEITTTPSLKEYLSTNPKPKIVLRTSARLNSDNVTEKEQNNYLYNTIESELLKSGFIVRDRQLFEKIVTNSDNNTNYENLKQKSDTDLIIELTNLDRSIIYQTNTYSDENGKEKTSSMLATKIFYGATIEFKVIMIETNEFAGIYKFNYVPCVDGCETRPAKRLTKRELDERTIESYEAVEEDKLIEFTRNATRQLISEMRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBS7</accession>
    <name>A0A5C6ZBS7_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alanine racemase</fullName>
            <ecNumber evidence="3">5.1.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">alr</name>
        <name evidence="7" type="ORF">ESY86_18240</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>L-alanine = D-alanine</text>
            <dbReference type="Rhea" id="RHEA:20249"/>
            <dbReference type="ChEBI" id="CHEBI:57416"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="EC" id="5.1.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 3 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the alanine racemase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.1.1" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000030">
        <property type="protein sequence ID" value="TXD87073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00042">
        <property type="reaction ID" value="UER00497"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008784">
        <property type="term" value="F:alanine racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030632">
        <property type="term" value="P:D-alanine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01201">
        <property type="entry name" value="Ala_racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000821">
        <property type="entry name" value="Ala_racemase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011079">
        <property type="entry name" value="Ala_racemase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00842">
        <property type="entry name" value="Ala_racemase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00992">
        <property type="entry name" value="ALARACEMASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01005">
        <property type="entry name" value="Ala_racemase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50621">
        <property type="entry name" value="SSF50621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00492">
        <property type="entry name" value="alr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3 4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ala_racemase_C" evidence="6">
        <location>
            <begin position="243"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; specific for D-alanine" evidence="3">
        <location>
            <position position="38"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; specific for L-alanine" evidence="3">
        <location>
            <position position="264"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="313"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="3 4">
        <location>
            <position position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR600821-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR600821-52"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD87073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="368" mass="40777" checksum="F57BF9CBA98B19AA" modified="2019-11-13" version="1">MPKAQETLLEIDLNALKHNYNYITSKLKKDTKLLAVVKAFAYGSDANEVAIMLEELKVDYFAVAYIQEGVALRDAGIRTPILVLHPQPVNFKLMIDRCLEPNLYSFRVLEQFIAIASEAKQTNYPVHLKFNTGLNRLGFTMDDVDSLTSKLKQTSVIKTKSLFSHLAASEDMDERPFTLKQISLFKTIAEAFADKIGYMPLLHISNTSGVLNYPEAQFDMVRTGIGLYGFGNAEAVDKELKPVASLKSVISQIHQVNTGESVGYNRGFIAKSPQKSATIPIGHADGIGRFYGHGKGFVSINGKQAPIIGNVCMDMIMVNVTDIDCDEGDEVIIFGKDLDANRLAKQANTITYELLTAISQRVKRVFLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC16</accession>
    <name>A0A5C6ZC16_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF418 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_20135</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000058">
        <property type="protein sequence ID" value="TXD86458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007349">
        <property type="entry name" value="DUF418"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04235">
        <property type="entry name" value="DUF418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="236"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="270"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="307"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="348"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="378"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="domain" description="DUF418" evidence="2">
        <location>
            <begin position="255"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="418" mass="49609" checksum="DC14B7820D5B5262" modified="2019-11-13" version="1">MSTKLEPTKLTERIPSLDFLRGIAILGILFINIESFVYPNPWSSYQYGFQTSLDNSTRFWVYFLTQGKFYNMFALLFGVGFAIFLERLELKNIGLKGIDIYSRRLLWLFIFGVIHAYFIWNGDVLYHYAICGLILLPFRSINSKYIILIILFLASFSIIKSVTTTSERIEKYKEYQEAIRTNMSERTDEQNLKINSWEKRYSKKITSNDKVENPKPTYFEGLKKSYQHATVHKGEFYYQSLLFVTLIIMLLGIVLYRAGIFSDYTVWKHYWLISLAVLTVGLLINYFRFYHWTFEDHKPVLNIWQSVMFTFPKEILGFGYILIFNGLYQKYLKNAKIKFISKIGRTALSNYIFQSIILGFIFYGYGLGRFNQFSRFELLPIVITIWIIQIILTLIWLKYQKQGPLEKLWRKLTYKSFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCD4</accession>
    <name>A0A5C6ZCD4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF559 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000030">
        <property type="protein sequence ID" value="TXD87066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007569">
        <property type="entry name" value="DUF559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04480">
        <property type="entry name" value="DUF559"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF559" evidence="1">
        <location>
            <begin position="10"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="119" mass="14237" checksum="5E6E67FAA3017C4B" modified="2019-11-13" version="1">MTNIHNRKYLEERRKSLRNNSTSAEVTLWKSLQRQQLKGRKFRRQHSITNYIVDFYCPAERLILELDGGYHLDFAQANYDNERTKALEALGFKVIRFENKLVFEDLKGVLEEICKHFKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCF9</accession>
    <name>A0A5C6ZCF9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_17545</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000027">
        <property type="protein sequence ID" value="TXD87274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="280" mass="32838" checksum="B867453D44F6E79D" modified="2019-11-13" version="1">MLGFSQQLMAQTSDLFRAEYLNVPNNNTGNSVSRFRTLFQLPLEFKKDNFIIIGGEYRYTKLDLQDDLPFSIDDLNAVQRIEGSLGYLHKTQGDWYYAAKAAVRLQSNFETKLRSDDYIYAANVFFIRDRTKRKDGIPDRLIMGLEYTTTPGRNFPLPILNYYREFHPDWTYTLGVPKTNLRYKFDKTNHVQAFLTLDNFFANIQGNKEVNGKIAENISMTTVLAGLGYEHYFTDHIMYYGYAAYTISNDFRLRNNKRDDIYTIEEKNTLYFRTGIKFKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCL8</accession>
    <name>A0A5C6ZCL8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Conjugal transfer protein TraK</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17865</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000028">
        <property type="protein sequence ID" value="TXD87181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="202" mass="23244" checksum="34A2190353F89BB6" modified="2019-11-13" version="1">MKTPYRNIYSVLKVNRIIVISVVVCALLLSLFSVWIVFQTNEKALNSAFAINTDGSIIPLKIVSQKENFKVEALAHLDLFHNYFYNIDASNYEKNLKKALWLGNSSVDNLYRQKRAEGVYNRLLQFSLVQKVLSIETQIENSKASYKFQTTTRFEINRGAVIDTYELITTGKLIIVDRNFPNNPHGLLITDFFEKSLKKLNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCR5</accession>
    <name>A0A5C6ZCR5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_17640</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000027">
        <property type="protein sequence ID" value="TXD87257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045534">
        <property type="entry name" value="DUF6428"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20001">
        <property type="entry name" value="DUF6428"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="155" mass="17367" checksum="ADEC68FC07A4C171" modified="2019-11-13" version="1">MKLSEIKTALNNLEHISFQLPNGSLVPNHFHVTEIGKVSKTFIDCGGTKRHEDRVNFQLWNANDYDHRLHPEKLVDIITLSEQLLDLEDLEIEVEYQAETIGKFGLDFDGTTFLLTSKQTDCLAKDNCGIPEEKPKTRLSTLQSASSCEPGSGCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD36</accession>
    <name>A0A5C6ZD36_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_16175</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="65" mass="7666" checksum="031BC27948E5AFCB" modified="2019-11-13" version="1">MDFRLRDLPSGGQAAVASFIGRHKTQWYGCLKRYDEQPDAWATFGWARVRPEKKVLSTLRFEYKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDA4</accession>
    <name>A0A5C6ZDA4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000031">
        <property type="protein sequence ID" value="TXD87038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022738323" evidence="1">
        <location>
            <begin position="19"/>
            <end position="591"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="591" mass="68850" checksum="35B7A54488E6CE68" modified="2019-11-13" version="1">MKRIVLLFLLLAAGSLHAQDEILANGYFERGEFEKALLTYQKLYEQSKNNTYFEKIVESLQQLERYDESEKLLMQRLTKQNYPPVMVELGYNYQLKGDQNSADDYYNKAIARVDENPSYSFGIARRFEDYSLLEYALEVYKKGMALNPDYNFSLQMARIYGEQGNIEQLFSSYLDYLELNPSFLGNAKRAFSDFVSENKENENNRILRVLLLKELQAQPDVYWYDLLSWLFIQQKEYNKAFTQEKALYKRNPESLRRIIDLALTSLTANDDETAIAIFNYILENSQDIQTVLLAHQYLLDLEVENADIKTLESVDAKYQALIEQYGINEQTLGLQIGYGNFLAFYNDQPEAASQFLKESLSLPLSVYEEAEIKMKLADILVYQERFNEALIYYSQIQANVKNSSISQEARFKVAKTSYYKGDFDWAESQLKILKASTSQLIANDALELKLLISDNKDEDSLQTALKLYAKADLMSFQNKNERGITLLNKILTEHKGESIEDQALYMQAKLFEKTNQLEKAVANYEYIIANYRDEILADDAYFYLAELYETQLAQPEKAKDLYEKIIFNHQDSIYFVEARKRFRMLRGDAIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDR5</accession>
    <name>A0A5C6ZDR5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Eco47II family restriction endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_14235</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009036">
        <property type="term" value="F:type II site-specific deoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019057">
        <property type="entry name" value="Restrct_endonuc_II_Eco47II"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09553">
        <property type="entry name" value="RE_Eco47II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0540">Nuclease</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="254" mass="29262" checksum="0174F3574124D05A" modified="2019-11-13" version="1">MANKYLSYISDEHFLSCIENLHKSYLKAKANVSKKKFYSNKIDTIKLTFDAKFNELDEETLIKTEINRQIDKSINNSIGTFHEQILGGIEGFEIGKMSGFDIKATDDTLFADMKNKHNTMNSSSAESLFQKLATFADTYKMANCYWVQILAKNSFNEKWYGDINGKEYSHSRVYKISGDEFYKLLTGKSDAFLELYTALPIAIDDYLRHYKPTDTLKNSALEEIKASSGLPKRRILDEITFENYSYYLGFDSLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDR9</accession>
    <name>A0A5C6ZDR9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Gfo/Idh/MocA family oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_16455</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87619.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="5"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA_C" evidence="2">
        <location>
            <begin position="138"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87619.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="325" mass="36643" checksum="DF9A1D8A97E51A5E" modified="2019-11-13" version="1">MEKMIRWGIVGCGNVTEVKSGPAYQNTEGFELKAVMRRDVAKAEDYAKRHQVPKFYGDAEALINDPDIDAIYIATPPNSHEDYALKVAEAGKICCIEKPMAPNYEACVRINAAFEKKNLPLFVAYYRRSLPRFDQIKTWIDAGEIGDIRHINWNLTKPPSNVDLAEGYNWRTDKSIARGGYYDDLASHGLDLFVYLLGPVSEANGIGVNQQKLYSAMDAVTGYWLHEAKITGSGSWNFGAEEHQDKVEIFGTKGTISFAVFEEENIILRTGDQEESLWIPNPKHVQKYHVQNMAAHLNKEKTHPSTGKTAVHTAWIMESMLNRMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDZ5</accession>
    <name>A0A5C6ZDZ5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">HTTM domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_18460</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000031">
        <property type="protein sequence ID" value="TXD87040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008488">
        <property type="term" value="F:gamma-glutamyl carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017187">
        <property type="term" value="P:peptidyl-glutamic acid carboxylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011020">
        <property type="entry name" value="HTTM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007782">
        <property type="entry name" value="VKG_COase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12639">
        <property type="entry name" value="PTHR12639"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05090">
        <property type="entry name" value="VKG_Carbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00752">
        <property type="entry name" value="HTTM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="64"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="148"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="200"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="234"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="290"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="HTTM" evidence="6">
        <location>
            <begin position="6"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD87040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="440" mass="51900" checksum="FA19CAD22457A6B6" modified="2019-11-13" version="1">MRDFLFKRIDNSALVIFRVIFGFLIFLEAVGSIFTGWIKRTLIDPDFTFNFIGFEFLQPLPGNWMYAYYAIMGLLGIFVMVGYKYRWSMLGFTLMWASVYLMQKSSYNNHYYLLMLLNAMMVIVPAHHYFSVDANRNPSLRSISMPNWCRWMFIIQMIIVYTYAAKAKMYPDWLDLSVPELLMRSKKDYFLVGDLLQNRWVHYGLAYGGILFDGLVIPLLLWKPTRKFAFFASIFFHLFNSFIFQVGIFPYLSLGFALFFFEPKLIQKLFLKRKPFYSEAEVIAPKHAKLFMLLFVSYFVIQVALPLRQYLYPDNVLWSEEGHRLSWRMMLRSRSGNTNYRVVDKATNEVITISLKDYLTPKQIRSVSAKPDVIWQFAQRLKSVFAEKGMDVEVYVSSFVSINGKKSQRFIDPKVDLSAVKWHHFKHNDWILPSKLDENP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDZ7</accession>
    <name>A0A5C6ZDZ7_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pantothenate synthetase</fullName>
            <shortName evidence="5">PS</shortName>
            <ecNumber evidence="5">6.3.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Pantoate--beta-alanine ligase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Pantoate-activating enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">panC</name>
        <name evidence="6" type="ORF">ESY86_13735</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>(R)-pantoate + ATP + beta-alanine = (R)-pantothenate + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10912"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15980"/>
            <dbReference type="ChEBI" id="CHEBI:29032"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57966"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.2.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantothenate from (R)-pantoate and beta-alanine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="5">The reaction proceeds by a bi uni uni bi ping pong mechanism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the pantothenate synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.1" evidence="5"/>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00028">
        <property type="reaction ID" value="UER00005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004592">
        <property type="term" value="F:pantoate-beta-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00158">
        <property type="entry name" value="PanC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003721">
        <property type="entry name" value="Pantoate_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042176">
        <property type="entry name" value="Pantoate_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21299:SF1">
        <property type="entry name" value="PTHR21299:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02569">
        <property type="entry name" value="Pantoate_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00018">
        <property type="entry name" value="panC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 5" id="KW-0566">Pantothenate biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="37"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="30"/>
            <end position="37"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="150"/>
            <end position="153"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>(R)-pantoate</name>
            <dbReference type="ChEBI" id="CHEBI:15980"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="187"/>
            <end position="190"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD88156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="283" mass="31790" checksum="66B5A4508CE63008" modified="2019-11-13" version="1">MKIFENKEDLTVFLDAKKNKGLAVGLVPTMGALHEGHVSLISKGLADNDLVVVSIFVNPTQFDKEEDLIKYPRTLASDIALLKTVSEETILVFAPSVADIYGTTVASQHFDYDGLEHEMEGRFRNGHFDGVGTIVKRLFEIVKPQKAYFGEKDFQQLMIIKKLVAIEKLPVDVVGCDIYRANDGLAMSSRNMRLAPEYREAAPFIYKMLQAAKTKFATDSAQHIIDWVNLQFENNELLELEYFIIANAETLKSIENKTTESSFRAFIAVYADGVRLIDNIALN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE09</accession>
    <name>A0A5C6ZE09_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000026">
        <property type="protein sequence ID" value="TXD87338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022746320" evidence="1">
        <location>
            <begin position="19"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="122" mass="14018" checksum="490EF0709FF9698D" modified="2019-11-13" version="1">MKNASLLFVLMLVVLLFACQSNENTQVDVKKDLITKFISSSKVNSTTHLGKIVILETEYCNSIDCQNYFKAYENEIIFYSKTELFMRAINNYVVIEKLDKDNGHLVLTKRSENGVETIEIKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE29</accession>
    <name>A0A5C6ZE29_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_15860</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="145" mass="16996" checksum="B9464C7E0C7DF1F2" modified="2019-11-13" version="1">MTFKQLILTNNWQKIAPLFLEIYPEAEKNMEGYQAVFEKLKVIDPEESDISIVISKEIDDDEEYIEACGLHKNPKNEDENYLQGIELTPWCKWLGMDISKESLNDFSELEIIVHCLYEMTFVGFSEEAIQEKINKIENNRTARNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEG9</accession>
    <name>A0A5C6ZEG9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pyridoxal-phosphate dependent enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_16180</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001216">
        <property type="entry name" value="P-phosphate_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00901">
        <property type="entry name" value="CYS_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PALP" evidence="3">
        <location>
            <begin position="9"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD87574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="326" mass="35860" checksum="FEB3B0CAC78DCBBA" modified="2019-11-13" version="1">MTYAENILETIGNTPLVKLNKLTAELPCLVLSKYETFNPGNSVKDRMAVKMIEDAEADGRLKPGGTIIEGTSGNTGMGLALAAIVKGYKCIFVISDKQSKEKMDVLRAVGAEVVVCPNDVPPTDPRSYYSVSKRLGEETPNSWYVNQYDNPSNCTAHFKSTGPEIWEQTDGKVTHFVVGVGTGGTISGVGSYLKMKNPKIKIWGVDTYGSVFKKYHETGIFDENEIYPYITEGIGEDILPLNVNFGVIDGFTKVTDKDAAVYTQRLAREEGMFLGNSAGAAIKGVLQLKEHFTKDDVVVVLFHDHGSRYVGKIYNNDWMRAQGFIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZES2</accession>
    <name>A0A5C6ZES2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_13490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035958">
        <property type="entry name" value="SecB-like_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="152" mass="17375" checksum="7A9BF5CB7F51F4DE" modified="2019-11-13" version="1">MSEIKINPEKLHLFHINVIESSIKDLPNKGKIPFSINVAHKTMHNLKDERIKIGLLIDLQTNSSETNNANAHFSIDFHFQIEELKKYFELSEKNEPVFSGLLIATLLGVSFSTARGIIYERLSNTNMQGMILPVVSPQKMLLQQTEEDKNRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEY0</accession>
    <name>A0A5C6ZEY0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12775</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="175" mass="20396" checksum="C816ED3B68A0B9A0" modified="2019-11-13" version="1">MDTSLLNNYVLKAMDAYPYDLEETAENLNYALAYDANDPHALYLMGRLQAEQFGDYEKAKSYYAAALANNLYLFKVYEHYILVLLWNEDYEEAEKLIAFAFKVKGLDKGLVYALQGRLLEHQHQLKKALKAHKKAKLHGFDDDFLNSINTEISRIKKKKKSEKAKKSKHQKKRKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEY5</accession>
    <name>A0A5C6ZEY5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_13775</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="130" mass="14845" checksum="8650E8E63A92AD3F" modified="2019-11-13" version="1">MHRNSRDVDYNYVSVMHKSRPSLLEVIEIGSISIFIEETLVYKSAGMGGNPNMPGFPATGSTIRQEIDIFLLRTKDKKASNLEAVLNFKKAALEFFEDCPVLLKRIKNRAYGRGDSLEMAYYYNDFCAEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF92</accession>
    <name>A0A5C6ZF92_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta fold hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_14695</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="12"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="257" mass="29219" checksum="A38FAFFB027E6870" modified="2019-11-13" version="1">MALHSQILGEGKPFIILHGFLGMGDNWKTLGTKFSEVGYEVHLVDQRNHGRSFHDADFSYEVMAEDLKTYIDAHKLKEALLLGHSMGGKTAMLFATLYPELVSKLMVADISPRYYPVHHDAILDGLSQLDFDSIKSRGEADKKLKRYVPDVGTRLFLLKNLYWIKKGTLALRMNLEVLKEHVSEVGEALPMHANFDKPTLFLRGDKSEYVMPSDETIIKQHFPQAKIETIGNAGHWLHAENPDDFYDAVQDFLNFDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFI9</accession>
    <name>A0A5C6ZFI9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Rho termination factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_15075</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011112">
        <property type="entry name" value="Rho_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036269">
        <property type="entry name" value="Rho_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07498">
        <property type="entry name" value="Rho_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68912">
        <property type="entry name" value="SSF68912"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rho_N" evidence="2">
        <location>
            <begin position="50"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="84" mass="9245" checksum="883680D135DD2E05" modified="2019-11-13" version="1">MGKQTDHGPSIKDDETYEALRDEGYSKEKAAKIANTKNPGKKGGGAKPYEERTMKELYEQAKTVGISGRSTMKKKALIKALRAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFM3</accession>
    <name>A0A5C6ZFM3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HD domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045509">
        <property type="entry name" value="HD_assoc_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19276">
        <property type="entry name" value="HD_assoc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="1">
        <location>
            <begin position="57"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="407" mass="47088" checksum="606F50B5CB8FD383" modified="2019-11-13" version="1">MKLSNKLKIFNDPIYGFITIPNSLIFDLIEHKYFQRLRRISQMGLSYLVYPGAHHTRFHHAIGCMHLMQKAVNVLRFKGVDISEDEENALYIAILLHDIGHGPFSHAMENSIVSGVSHEYISTLFMENLNREFNGRLTLAIQIFKGNFHRPFLCQLISSQFDMDRADYLKRDSFYTGVAEGNINSERLITMLNVKNDRIVVEEKGIYSVEKFLVARRFMYWQVYLHKTSVVAEQLLTRVLKRAKELTENGVALSASAPLQFFLSTKISSENFDDSILDTFSQLDDTDILAAMKAWQYHDDFVLRHLCSMIINRDLLKIKLKNNPIKPTVLHQKIKTLMLRYPISEAEADYFVFTGEVYNQAYQSDIEQIQILQKNGKVVDISKASDQFNIVALSKPVTKFYICYPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFM7</accession>
    <name>A0A5C6ZFM7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Dihydrofolate reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_14240</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2-Hacid_dh" evidence="2">
        <location>
            <begin position="18"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="2-Hacid_dh_C" evidence="3">
        <location>
            <begin position="132"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="303" mass="33766" checksum="8AB79B96D1AB00CC" modified="2019-11-13" version="1">MFKKLVGIDPLDLISTANKKLESFTEALTLHEDQPLNAEEIVKRIGDADGVLVSHRSQLGRDILEQCPNLKYIGMCCSLYSPESANVDIHYANSQGISVKGVHDYDNEGVVEYVVSELIRCLHGFGHREDGSDRQTWSEVPREITGIRAGIIGLGETGGMIADALHLFGAEISYFARSEKQDAKTKGYTYLPLKELLSKNEVIITCLNKNTILLHEEEFRAMGNRTILFNTGLSPAWDPKPFEHWLHGDNLVFCDSLGALGGERFLKYTNIHCLQVSTGRTKQALERLSEKVLANLTAFAEEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFP4</accession>
    <name>A0A5C6ZFP4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type II toxin-antitoxin system RelE/ParE family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_14250</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009241">
        <property type="entry name" value="HigB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05973">
        <property type="entry name" value="Gp49"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="109" mass="13338" checksum="99C1B8CCEE9A3DD3" modified="2019-11-13" version="1">MNKKRELYFFKDYFEDFYENQTDKVKKKIIWTLKVIEEIDRIPEIYLKHLKNTTGLYEIRVQVGNNIFRIFCFFNFDNIVVAGHGFQKKTQKTPKQQIERAEQIKKRIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFW6</accession>
    <name>A0A5C6ZFW6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_13790</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022714240" evidence="1">
        <location>
            <begin position="20"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="93" mass="10164" checksum="C1B2E33DC16F6949" modified="2019-11-13" version="1">MKNLFFALAFMLVGTFAFANDFCEETSINSKDKLEESSENNEKKNLVDAKAAEGPCFIIVQTKHKDGTRTLHGSVYTAEPGCSGTAVLTINEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFW7</accession>
    <name>A0A5C6ZFW7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_15710</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002559">
        <property type="entry name" value="Transposase_11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01609">
        <property type="entry name" value="DDE_Tnp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_1" evidence="2">
        <location>
            <begin position="80"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="145"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="150"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="435" mass="50727" checksum="13901410917C60D0" modified="2019-11-13" version="1">MKQSGVPFWELIKLILALPFMDVESIGSVFDGKSTVDVKAQKDTYYRALTNQKMDWRNLLLLFVKRYLSLDRDFTTPEDDHKCLIFDDTDIGKRGKKIEGLSKTFDHVNHRFIFGFKLLVAGYWNGSVFIPVDFSFHRENKDNKKNKYGLTGKQRKQQKKTKRGKGLPVVKRFRELNSKKTGMLVDMFKRINQRKIEVDYILTDSWFTSISLINKLLKVNKKVHVIGMYKYNSKLSIDGKEHSIKQLRKRKGKMSRQRSLKLYYFQYVGEIDGVKVKVFLSKRGVNGAWHTIITTNTKLSFKKTMEIYSIRWTIEVFFKEAKQLLGLGKCQSTNFDVQVAQTTLTMVRYLLISLRHRMEAYQTIGGIFKDIKQDYLEHKLNERLLLAIVDILEVLDLLVKDIDINSIARRLVLYNESLSFLTYPPDPANNSKLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFW8</accession>
    <name>A0A5C6ZFW8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_12300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="74" mass="8412" checksum="F96F869E4F30BF5C" modified="2019-11-13" version="1">MPSNDLKMGLVTLGNEKENVSAAHIQFDFSYEASEKGQLKFTSVEGMNIYRIIQQSIHNAIKYDEAEHIEVICH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG06</accession>
    <name>A0A5C6ZG06_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2007 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_13660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018551">
        <property type="entry name" value="DUF2007"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09413">
        <property type="entry name" value="DUF2007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2007" evidence="1">
        <location>
            <begin position="6"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="144" mass="15934" checksum="BF65788DF759F34D" modified="2019-11-13" version="1">MSDAFKTIATFQYSSEAQIIKGRLEADDIEVFLQDRFTIDTDPLVSNAIGGVKLRVKAKDAMKAQYILSSIKQYALDDDGNALHCPNCHSEKIEIYSTIDSLKSLLAFVIGLVSGTLPFHTLYKYECDACGKEFSVEDVKPKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG49</accession>
    <name>A0A5C6ZG49_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15395</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022671722" evidence="1">
        <location>
            <begin position="32"/>
            <end position="796"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="796" mass="90433" checksum="64576EB6FB15B4AB" modified="2019-11-13" version="1">MHKPLTFRLNRNFSIAVFLFCFSLFSFLVEAQTANNSLLDNFQAYTKLPREVTYGHLNKSTLIKGETLGFAIYVYDKNLKAPSNSTTNIYCSLENESGEVLKKSLILAENGVANGVFEIDSLFDSGNYIFKAYSNWMKNFNEQNFYIENLKIINPEDYKKEVTTNSQDIDVQFLPEGGHLIANVNNSIGVTIKNNLGYGIPNLSAGVYDNTGTEITNFKTNALGLGKFSIKPVDQERYTVKIKEVETPQINLSPAESIGLNLKLTDLGNRVALSIRTNPETLSQIESKPYKLSIHNGNLITIVDFNFGSELEVTKVLNYENLFEGINIFTVFNEDGQPILERLFFKYDGIGIVKSETIVTKREPDSVVVTVPFEAAFSEKFSSLSVSILPEHTKSNNNHQNIISQVYLQPYVRGFIENAKYYFQDIDRQKKYELDMLLLTQGWSSYDWTNVFSHTPEVGFEFENGISFKANTRNSKEDQFVVYPLKNSPTVMTNIKEGQKSFEVKGLLPEDDEKINIGGISNRENVNKPSIYLQFYPSKVPSLEKYAKFLPVKENRPFEGNENDPILVRAFEEIQALDEVVITAQKEVDRIEKITRRHNGRVDVFDDIQRNSFIDFASYISSRGFVVNQTATDLNISTARTISLNASRTPLIYMDNFLLNDFSILLNYDMANVDYIVIDKSGLGEGMRGAAGVIKIFTDPRVMLNSPLNRDVTQIVDIPLTFTSPKKFYTPKYTYYRSNFFQNYGVIGWEPKLKIDSNGNLNFKIPDTGNERLKLFIEGVANDDEFVTEEKTIVIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG54</accession>
    <name>A0A5C6ZG54_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_13205</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045857">
        <property type="entry name" value="O16G_dom_2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="589" mass="66638" checksum="D3F71CA970F24358" modified="2019-11-13" version="1">MDDITQNTANNSENTEVFKGVMLNAYPDSIGNTLSDAVAMLKMPAFKDVFSMFYVLPTFFNSDLDRGFSIVDYDLNETLVSPEDLAALDELNIMLKLDIVLNHISVASPQFKDVLQHGEASQYKDFFINWNEFWEGNGTLSADGVVIPDAEFLNKLFMRKPGLPVLNVLFPDGSEKPFWNTFYQSIHYHEITIQDLKGLKIFSTEEMLVICEKVNSALAKNQDFKSIDFGINKHFKSDIIQIVKKKRTYLGQMDVNAKSDLVWNFYEETLSKLNHFGCKILRLDAFAYLHKQVGQTNFFNKPGTWDYLERIKKMAERNKLMVLPEIHAEYGLGLHDEVAKKGFPIYDFFLPGLMIHTLENGSSKALISWVTEIIAEDYKTVNMLGCHDGIPVLDLKGKEVDGTYNKGLLEDADIEAIMETIIARGGRVKNLYDPAGRKISYYQVNATFFSALGEDERKLLLARAIQMFMPGIPQVWYLDLFAGKNNYEAADQGGSAGHKEINRSSLTMDAIEKGLKTPIVLNQLKIMRLRNTSKAFLGMVSIKDSPDHELDISWTFGQDSVQLKANLKSCDFTIDQAASGMAHRLVFQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG60</accession>
    <name>A0A5C6ZG60_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_16495</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87627.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="9"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="76"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="133"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="162"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="213"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="245"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="275"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="298"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="336"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="363"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="9"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD87627.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="387" mass="41901" checksum="E4000A778D1E57D0" modified="2019-11-13" version="1">MKQQLSNPVLYLMSISAGLVVANLYYNQPLLHQMAERFGVSESAISNVALSTQLGYAFGLLFIIPLGDKISNKKILKYDFLLMILSLIAAALSESVWLLIASSFFIGFSSAIPQLFVPMAAQLASEKDRGRAIGIVMSGLLIGILGSRVISGFVGAAFGWRVMYWAAAGLMLLLFILLHYKLPKLTPQYHGSYGSLLKSIGHYFKTEPSVRLAALRGGLSFAGLSAFWTTLVFLMEDSFGYGSDVTGAFGLFGIVGAVAATVVGKFSDRFSKNKIILYAAVLMIISWVVLYFSASSIFGLIVGVVLVDLAMQALHITNQNIIFSKNQEARNRINTIYMVGFFVGGAIGTTAGAFAWSRYGWNGVSTLGIIFSAAIVVAHVIFRKKTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG93</accession>
    <name>A0A5C6ZG93_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="60" mass="6400" checksum="236416CCBC21EBF8" modified="2019-11-13" version="1">MAMNKNTVLAWATTIMIIVGLGLMAMGAFRYDDVAGWGFGAVGVGFFAIAWVFNALKGRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGE8</accession>
    <name>A0A5C6ZGE8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GNAT family N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="9"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="174" mass="20411" checksum="4D77132B9860FB97" modified="2019-11-13" version="1">MVTLKGAKIFLRALEPEDLGFLHEIENDESVWDISHTNTPYSKFILQQYLENAHRDIYDVKQLRLVICNYENETLGLIDIFDFDVKHKRAGIGVLIKDAQHRARGFGKEALQLLINYCASHLDMHQLYCNISEENTQSIRLFQNQGFEIVGLKKDWNFIKGNYKNEYLLQRIFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGF9</accession>
    <name>A0A5C6ZGF9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_09005</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="109" mass="12637" checksum="540ABE65905BA163" modified="2019-11-13" version="1">MKPKNANLKRVIVDFKKLTPEILALLVEKYPDGYDDEQIISFKNANNELVEAVEVTTKDTKYLVKVSTKLEVTMENYDEDDYEAFDTDDPEAVQEPEMDPEDEIEEDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGG2</accession>
    <name>A0A5C6ZGG2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008719">
        <property type="entry name" value="N2O_reductase_NosL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41247">
        <property type="entry name" value="PTHR41247"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05573">
        <property type="entry name" value="NosL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023016500" evidence="1">
        <location>
            <begin position="22"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="145" mass="16030" checksum="CCE1441AB68A758F" modified="2019-11-13" version="1">MKTLKHISILALLTLILGCNAAPQPIDYGNDGCAYCSMTIVDKTHAAEIVTKKNKVYKFDATECMINFMDEFDTSEIELYLSNDYSEPGTLIDAKKATFLISKNISSPMGAFLSAFEKKAAAEDMQADKGGDLYSWEELLAHLKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGJ4</accession>
    <name>A0A5C6ZGJ4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039426">
        <property type="entry name" value="BtuB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30069">
        <property type="entry name" value="PTHR30069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0675">Receptor</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023122980" evidence="1">
        <location>
            <begin position="20"/>
            <end position="666"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="666" mass="74764" checksum="01D454464DFCA7AE" modified="2019-11-13" version="1">MKKGILCCFIVFFCGLVYAQQENNDVKKDTTILNEIIVVGQRKLSNYRQEKTLSSIDDYLEKSNKVTMIKRGGYAWEPALNNMNSERLNITIDGMQIFGACTDKMDPITSYVDVSNLDKVSIGSGQSGTENGHNVGGGIDLQLAASKFHGAGLITNVDLGYETNGNYRIRGMDLEYSGQAFFLNFDGIYRKSDNYKAGGDKEVLYSQFEKFNLSLQTGYKLSEHQTLEAHAIYDKATNVGYPALPMDVSLAEALITSITHSFKADSAFIKSLESKLYFNTITHIMDDSQRPEVPIRMDMPGWSDTYGFYSKASIQENKHNISLNLNGFYNRSLAEMTMYPNDPNQSAMFMYTWPDIRTLYSGVYAKDDFQMSNNETLSVSSRLGYHRNKIAEEVGLGSLQIFYPQLKASKSRVLSSFAANYLIKKPQHDVSFGLAYGERAPSVSEGYGFFLFNSFDNYDYIGNPTLANEKAIEANLKANYHKNRFHIGFEASYFHLMDYIIGDIAETLSPMTIGATGVRIYKALSNASIFDVYLNSSYKLSEALAVNATLGYNRGRGSNDENLPLIKPLSFMAEFNYNTPKFNAALQLEANGNQSNYSGFYGEDETPAYGVLNLNFGNLFYMKTNKVVFKYGVENVLDTNYSTFADWNNIPRQGRNVYANLSVVLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGJ5</accession>
    <name>A0A5C6ZGJ5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DUF255 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_09300</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13098">
        <property type="entry name" value="Thioredoxin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023028541" evidence="3">
        <location>
            <begin position="21"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="7"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD89233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="182" mass="21262" checksum="1D433FC03B0FC47F" modified="2019-11-13" version="1">MNKRILFIAVALMTSITAVAQEINWMSFEEALEAQKKKPKKIMMDVYTNWCGPCKMLDKNTFQNKDVAKYVNENFYAVKFNAEGNDVVTYKGQTFDNANYKEELKNRRNSVHKLARHFKVSAYPTIVYMDEKGEVIAPIKGYQKPQQIELYLKMFSSDAHKNLTTQEDFNTYYKAFTPEFTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGJ6</accession>
    <name>A0A5C6ZGJ6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4345 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12925</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025597">
        <property type="entry name" value="DUF4345"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14248">
        <property type="entry name" value="DUF4345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="131" mass="14675" checksum="74B509339638E1C8" modified="2019-11-13" version="1">MKTKTDFINKIHLIISACIVVPIAFVYGFNPGLSFDMSLETIDEHNFYKAIMGLYLGFSALWILGVFKNQYLKTAVITNLIFMLGLGFGRIISILMDGIPTSGYVFGTVAELFLGFYGLWVLKRLAEDKCV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGK0</accession>
    <name>A0A5C6ZGK0_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">5'-nucleotidase SurE</fullName>
            <ecNumber evidence="5">3.1.3.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Nucleoside 5'-monophosphate phosphohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">surE</name>
        <name evidence="7" type="ORF">ESY86_09320</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>a ribonucleoside 5'-phosphate + H2O = a ribonucleoside + phosphate</text>
            <dbReference type="Rhea" id="RHEA:12484"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:18254"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58043"/>
            <dbReference type="EC" id="3.1.3.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="5">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the SurE nucleotidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.5" evidence="5"/>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106411">
        <property type="term" value="F:XMP 5'-nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1210.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00060">
        <property type="entry name" value="SurE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030048">
        <property type="entry name" value="SurE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002828">
        <property type="entry name" value="SurE-like_Pase/nucleotidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036523">
        <property type="entry name" value="SurE-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30457">
        <property type="entry name" value="PTHR30457"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01975">
        <property type="entry name" value="SurE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64167">
        <property type="entry name" value="SSF64167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00087">
        <property type="entry name" value="surE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SurE" evidence="6">
        <location>
            <begin position="7"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="12"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD89237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="259" mass="28240" checksum="8375621DC7B75ADA" modified="2019-11-13" version="1">MSKKPLILVINDDGITAPGIRTLIKVMNSIGDVVVVAPDGPQSGMGHAITVNSTLFIEKITVDDGPQQEYSCSGTPADCVKLAIREILDRKPDICVSGINHGSNASINVIYSGTMSAALEAGIEGIPAIGFSLCNYNWNANFEACKAAVKTITEQVLKNGLNEGVVLNVNIPNLEEKDLKGIKVCRQARANWEEEFDKRQTPFGKDYYWLTGKFVNLDKGEDTDQWALDHGYVSVVPVQFDLTAHSSIQQLNSWELNGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGR9</accession>
    <name>A0A5C6ZGR9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L32</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">rpmF</name>
        <name evidence="6" type="ORF">ESY86_13045</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00340">
        <property type="entry name" value="Ribosomal_L32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002677">
        <property type="entry name" value="Ribosomal_L32p"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044957">
        <property type="entry name" value="Ribosomal_L32p_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35534">
        <property type="entry name" value="PTHR35534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01783">
        <property type="entry name" value="Ribosomal_L32p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="SSF57829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01031">
        <property type="entry name" value="rpmF_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD88438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="67" mass="7812" checksum="9EFB69F271E93F14" modified="2019-11-13" version="1">MAHPKRKISKTRRDKRRTHYKATAPTIATCPTTGEAHLFHRAHWHEGKLYYRGQVLIDNSEKEENAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGS7</accession>
    <name>A0A5C6ZGS7_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Phenylalanine--tRNA ligase alpha subunit</fullName>
            <ecNumber evidence="13">6.1.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Phenylalanyl-tRNA synthetase alpha subunit</fullName>
            <shortName evidence="13">PheRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13 15" type="primary">pheS</name>
        <name evidence="15" type="ORF">ESY86_13115</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) + L-phenylalanyl-tRNA(Phe)</text>
            <dbReference type="Rhea" id="RHEA:19413"/>
            <dbReference type="Rhea" id="RHEA-COMP:9668"/>
            <dbReference type="Rhea" id="RHEA-COMP:9699"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58095"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78531"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="13">Binds 2 magnesium ions per tetramer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 13">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 13">Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.20" evidence="13"/>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006432">
        <property type="term" value="P:phenylalanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00281">
        <property type="entry name" value="Phe_tRNA_synth_alpha1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004529">
        <property type="entry name" value="Phe-tRNA-synth_IIc_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004530">
        <property type="entry name" value="Phe-tRNA-synth_IIc_mito"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004188">
        <property type="entry name" value="Phe-tRNA_ligase_II_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022911">
        <property type="entry name" value="Phe_tRNA_ligase_alpha1_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002319">
        <property type="entry name" value="Phenylalanyl-tRNA_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11538:SF41">
        <property type="entry name" value="PTHR11538:SF41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02912">
        <property type="entry name" value="Phe_tRNA-synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01409">
        <property type="entry name" value="tRNA-synt_2d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="SSF46589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00468">
        <property type="entry name" value="pheS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12 13" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="9 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 13 15" id="KW-0436">Ligase</keyword>
    <keyword evidence="10 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11 13" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="14">
        <location>
            <begin position="108"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="250"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TXD88448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="339" mass="38715" checksum="2DC6E1E27AC5C5B5" modified="2019-11-13" version="1">MIDKIKALIAEAEAFQAQSTAEVEAFRIKYLGKKGLLNDYFAEFKNVPNDQKKAFGQIINKLKSTAEEKVNALKEELETKEETKGVYGDLSRPGEPIEIGARHPISIVKNQIIDIFSRIGFNVSEGPEIEDDWHNFTALNLPEYHPARDMQDTFFIQTNPDVLLRTHTSSVQVRYMESHKPPIRTISPGRVFRNEAISARSHCFFHQVEGLYIDKDVSFADLKQTLQYFTTEMFGKSKIRLRPSYFPFTEPSAEVDVYWGLETETDYKMTKGTGWLEIMGCGMVDPNVLENCGIDSKEYSGFAFGMGIDRIALLLHQISDIRLLSENDVRFLEQFRSAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGU5</accession>
    <name>A0A5C6ZGU5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HlyD family efflux transporter periplasmic adaptor subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_14440</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="454" mass="52161" checksum="EFA8EC39B1D1DDA9" modified="2019-11-13" version="1">MNNNKEIKNENTLGSESAQNSVTPSGARELGIELRSEEVQEILTKVPHWMIRWGNVLFLALILLLLFVSWFVKYPDVIAAEALITTSIPPQKEYAKTSGKLEAILVVDNERVESGKALAIIENTANYEDVYRLKTLIDTIRINRTNFEFPIDSLPILFLGDIDAQYALFENSYIQYSLNKQLQPFSNESLANRFSISELNRRLQSLKSQKEINATELEFERRNLDRNQSLFDKGVISAQEFENKQLTFAQAERNYKNFESSISQIREGISNARKTGKGTEIERVKEEMLLLKNVIQTFNQLKRAIRDWEQLYVLQSNIVGKVSFLNYYNVNQTVNQGDLVFTIIPSENSSYIAKLKTPAQNSGKIKVGQTVNISIDNYPDTEFGTLKGTVQHISALPNKDGFYLIDVLLPETLMTSYNKKIEFKQEMIGSAEIITEDLRLIERFFYQFREILKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGU6</accession>
    <name>A0A5C6ZGU6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="65" mass="7385" checksum="DDB5856B026460F1" modified="2019-11-13" version="1">MARVGTFNFAPLPTGRQVRGSTSRQASLREHKHSNVTLLKINAVEDDDEDEDEDEDENKDEEELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHD5</accession>
    <name>A0A5C6ZHD5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nucleotidyltransferase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_14265</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041633">
        <property type="entry name" value="Polbeta"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18765">
        <property type="entry name" value="Polbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Polbeta" evidence="2">
        <location>
            <begin position="17"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="96" mass="11148" checksum="DAD7DD3B04E9F64B" modified="2019-11-13" version="1">MKSLKDIKTTLEAHKSKLFSKYPIESMAIFGSFARNEETDHSDLDVIVEFNDDIGIRFIDLANELEKLMDMKMDLVSKNGIQKRYLQSIEDDLIYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHI8</accession>
    <name>A0A5C6ZHI8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Rhodanese-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_09120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="45"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="163" mass="18734" checksum="F58A1D7347902FC1" modified="2019-11-13" version="1">MKFLILMGVFSLPFFSFGQKTLEELLKVHNNNAVPYISVQELAMPKTEAVILDAREPEEYKVSRLKNAVFVGFNTFDLETTTSQLYNKQQHIVVYCSLGIRSETIAEKLKKAGYTNVYNLYGGIFEWKNEDFPVYNAAEQETDSVHAFSKVWGKWLLKGVKVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHK9</accession>
    <name>A0A5C6ZHK9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_13715</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039426">
        <property type="entry name" value="BtuB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30069">
        <property type="entry name" value="PTHR30069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023151338" evidence="5">
        <location>
            <begin position="19"/>
            <end position="923"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="7">
        <location>
            <begin position="115"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="6">
        <location>
            <begin position="459"/>
            <end position="901"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD88152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="923" mass="101117" checksum="DE1F9D5CDB490B99" modified="2019-11-13" version="1">MKTILKTMMLLCCALTFAQTTVKGKVTDNTGQPLPGANIIVVGTSSGTISDFDGNYTLTINQQPPFSIQVSSVGFETITKEVTQNGQTIDFSMAEGTSLDEVIISASRTPERIFESPVTVERFGLKDIKSASSPSFFDSIENLKGVDMNTSSLTFKSVNTRGFASFANTRFMQLVDGMDNSSPALNFALGNFLGMSELDINSVELLPGASSALYGANAFNGIMFMTSKNPFDHQGVSFYAKTGITSSDNAGDNNFVDAGIRVAKAFSDKFAAKASVSFLNGTEWFATDYRDFNDPGQTRLDPSFDGLNIYGDEVSTPLDFDEIAAGALPIPVLTNYGAATVSRTGYEERDLMDYNAESLKADFSLHFKPWANDFEIILNSKIGRGSTIYQGANRYSIKDFFMQQHKLEVRNKNFFARIYTTAEKSGNSYDSRFTGININRAWKADRQWFTEYAGAFIGNLAGQGIFANPTEGQIDAAHLAARAAADTGRLLPGTAEFEETFDRITSDGDLTTGSKFTDNSKIYHGDVNYNLGHVIDFADIQVGGSWRQYSLNSGGTIYTDFDGPIEYIEYGAYTQIQKKLVDDRLKLTGSIRYDKSEFFDGFLSPRLSFNYTADQNDNHNIRGSFQTGFRNPTTQDLFIGLNAGRAILVGSALDNLDRYTATSSQLSASGQNIVGANTVQLNGGDAYSNAFSRASIAAGNPQAANVNLVKPEKVTAYEVGYRGKVNRFVIDMSVYYNAYEDFISNRTVITPLYGEVGDNTLSLLALQNGDFQAYQTYTNSDAEINSYGGSIGVETSVLNGFDFGVSYTYAKLDFDQSQDPDFETSFNTPEHKVKASFGKTDLLKNFGFNVNWRWNDNYLWQSTFADGILPARNIIDAQVNFAVPSIKSMFKVGGANILSHDYVSAPGAGQVGAQYFVSWTINQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHP9</accession>
    <name>A0A5C6ZHP9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_13920</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="215" mass="25803" checksum="E34329F94F250256" modified="2019-11-13" version="1">MPEWQQCLDAGLKVDSTVAYFWQLKAMPYFKARKYEVGMVYIDKAVKYDRKRYLSYRAFIKCIFAKTYKDAITDFEACIEMEGNTYVMDHTYQFHIALSYLQLNEFEKAEAIFKKDISEQEEEWGEAHYLDLFYYGISKYEQGKWEEALYEFNKSLAIAPMFSDVEYYKALCLYRLSRFDECQALLKTAKEHAEEGFSFNEDNAIYETYPYQVRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHR4</accession>
    <name>A0A5C6ZHR4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Glucose-1-phosphate thymidylyltransferase</fullName>
            <ecNumber evidence="4 5">2.7.7.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rfbA</name>
        <name evidence="7" type="ORF">ESY86_07990</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>alpha-D-glucose 1-phosphate + dTTP + H(+) = diphosphate + dTDP-alpha-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:15225"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37568"/>
            <dbReference type="ChEBI" id="CHEBI:57477"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="2.7.7.24"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the glucose-1-phosphate thymidylyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.24" evidence="4 5"/>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008879">
        <property type="term" value="F:glucose-1-phosphate thymidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045226">
        <property type="term" value="P:extracellular polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02538">
        <property type="entry name" value="G1P_TT_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005907">
        <property type="entry name" value="G1P_thy_trans_s"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43532">
        <property type="entry name" value="PTHR43532"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01207">
        <property type="entry name" value="rmlA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="6">
        <location>
            <begin position="2"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD89712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="289" mass="31757" checksum="C4EA9980CE5B187F" modified="2019-11-13" version="1">MKGIILAGGSGTRLHPLTLTISKQLMPVYDKPMIYYPLSTLMQAGIKDILIISTPKDLPLFKDLLGDGKKYGCTFEYEIQDAPNGLAEAFIIGEKFIGTDKVALILGDNIFYGSGLSKLLQANSNPDGGIIYAYHVHDPERYGVAEFNAEGKVISLEEKPENPKSNYAVPGIYFYDNTVVEIAKNIKPSHRGELEITDVNKAYLDQGRLSVSILDRGTAWLDTGTFQSLMQASQFVEVIEERQGLMIGSIEAAAYEMGFISEAEFKALAEPLIKSGYGKNLLGMLKRNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHR8</accession>
    <name>A0A5C6ZHR8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FAD-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_10755</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003885">
        <property type="term" value="F:D-arabinono-1,4-lactone oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007173">
        <property type="entry name" value="ALO_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010031">
        <property type="entry name" value="FAD_lactone_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43762">
        <property type="entry name" value="PTHR43762"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04030">
        <property type="entry name" value="ALO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000136">
        <property type="entry name" value="LGO_GLO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="2">
        <location>
            <begin position="14"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="443" mass="50519" checksum="A8400811A179F36F" modified="2019-11-13" version="1">MNNEKIWKSWNENIQHSYKKLHTITSEKELQQIIIASENIKIFGNKQSSADISAGADTLIDMRAYDKMLSIDKKNMRITVESGMRLSTLLEKLEDLGWCIPCLPDINTITVGGALATGTHGTSGSILAQYMCACHVVLADGTIEEVTEKDPLMDALRVAIGMLGVISEVTFQCQPSYQLHLKEGPEKDEQWLSEIKTNLKKHDFLRILWLPHTGSGYVIKGDKIDAATPVQTKLGPKYLKHRRTVSKFLYQYSHRFAWTTALANKILYRLFFSSKKEHKGSLYQATVTKSRGSTLELAEWTVALDRFPQVFAEIKSELNAWSNKSFVHIPMDVRFIKKDQSWLSYAYGQDTVTMGCVSRNAATADTYEAFETVERIFLKHGGRPHWGKRFQAKDAQLSKLYPKWEDFKILRKQMDPSNKFLNAYTTALLNENPEDYKTQRVAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHS1</accession>
    <name>A0A5C6ZHS1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="12">DNA translocase FtsK</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">ESY86_11405</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FtsK/SpoIIIE/SftA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025199">
        <property type="entry name" value="FtsK_4TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041027">
        <property type="entry name" value="FtsK_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002543">
        <property type="entry name" value="FtsK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018541">
        <property type="entry name" value="Ftsk_gamma"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13491">
        <property type="entry name" value="FtsK_4TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17854">
        <property type="entry name" value="FtsK_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09397">
        <property type="entry name" value="FtsK_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01580">
        <property type="entry name" value="FtsK_SpoIIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00843">
        <property type="entry name" value="Ftsk_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50901">
        <property type="entry name" value="FTSK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="36"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="97"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="167"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="FtsK" evidence="11">
        <location>
            <begin position="451"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="245"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="468"/>
            <end position="475"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TXD88837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="804" mass="89173" checksum="7F71D2B92105A013" modified="2019-11-13" version="1">MAKKKTKTTKSKPTVGKATKKPSKTFSFKLSSQQKLIFGSLLIILGVLMFIAFLSFFFTGKADQSTLNQLASRDVKTENWLNKLGAWVSDLFIKKGFGISSFIFSGLLFLSGIYITLDINKSRLRRYWIWGTLIAIWLSVFFGFFAHKYDLLGGTIGFEVNSFLQDYIGKIGTILLLLFVLIVYLAIRFKVTGHSIVNLFKRAKSDIKSDFKSTDDPKEVALDNDLSAEAEDIKSAFDLKVTENKKMSEPKPAAKTETMHNVSVAKPSEEKSDDETELDIEIETVEEEVSEEDNLSNKLVEDFGQFDPTLELSKFQFPPLDLLKRYDTEGIKINQTELEENKNRIVETLNNYKIGIASIKATIGPTVTLYEIVPDAGVRISKIKNLEDDIALSLSALGIRIIAPIPGKGTIGIEVPNKNATIVSMRSVIASKKFQNCDMELPIAFGKTISNETFVVDLAKMPHMLMAGATGQGKSVGLNAVLTSLLYKKHPAEVKFILVDPKKVELTLFNKIERHYLAKLPDSEEAIITDNTKVINTLNSLCIEMDNRYEMLKNALCRNIKEYNAKFKARKLNPNDGHAYLPYIVLVVDEFADLIMTAGKEVETPIARLAQLARAIGIHLIIATQRPSVNVITGIIKANFPARIAFRVTSKIDSRTILDGSGADQLIGRGDMLFTQGNEITRIQCAFVDTPEVEKVTEFIGGQKAYPDAYLLPEYVGEDGGTTIDNNIDDRDKLFKEAAEIIVISQQGSASLLQRKLKLGYNRAGRIIDQLEAAGIVGGFEGSKARQVLITDLAALAILLSDEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHV8</accession>
    <name>A0A5C6ZHV8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Radical SAM protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10975</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD89004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Radical SAM core" evidence="1">
        <location>
            <begin position="341"/>
            <end position="557"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="623" mass="70844" checksum="A7BABB783AD176FF" modified="2019-11-13" version="1">MQSKILFITPPFTQLNTAYPATAYLKGFMGDHDIAVHSCDLSIELFTTIFTGDFLRSMFQEAQDLKHYDYPEVRKMKGKYMQCVDVVIPFLQKQDLETAHKILEADFLPLGHRLSKVNTTIKWEAGEIGIIDKAKHYGTLFIEEIGDFIQANVDEFFAFTKYAEQIATSASSFDEIDEFLSFQPTIIEAEMLDILMETIKKEKPLLVCFTIPFPGNLFAALRCAQFTKQFFPDIPVAFGGGYCNTELRSLTDPRIFEFVDFISLDDGEGPLLKMVQYLEGKVTIDDLERTYVLENNAVVYKNKIPNTIYHHRNLPAPDYSGLPFDKYVSFLDVVNPMHRMWTDARWNKMTISHGCYWKQCSFCDVSLDYIGNYQNTTAEDLVDKIEKIVKDTGITGFHFVDEAAPPKMLRALANALLERNVKITWWTNIRFEKTFSFELCELMAKSGCIAVTGGLEVASDRLLAKMKKGVDIAQVTRVTHNFSSTNIMVHAYLMYGFPTQTEQETIDSLDVVKQLFERNCIQSAYWHQFTTTVHSPIGKNPQDFGITITGPVFEGFAQNDLYHEDPLGADHPKYTKGLNLALHNYLNGTGFDEEMQHWFDFTVPATSQPAGMIEGFLGEVVGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI24</accession>
    <name>A0A5C6ZI24_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_06435</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="85" mass="9616" checksum="6DF156CAD40E9281" modified="2019-11-13" version="1">MKLPVIKHLTDFIEANDEDFINETIETLEALTEVPSLKDEELDVIGELISNMYGALEVHKMIKDGTPRKEALNAFMKRVLGSIDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI35</accession>
    <name>A0A5C6ZI35_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_13565</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="85" mass="10206" checksum="950DF298758CC3A7" modified="2019-11-13" version="1">MKQVKLAYYMKKDWNRFLESIDDRDSMFDSWKEWHKAYQKTKKGLTEKGFIVTDFVMDVDELINYCKIRGIKNDGKARSGFVIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI56</accession>
    <name>A0A5C6ZI56_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Dihydroorotate dehydrogenase (quinone)</fullName>
            <ecNumber evidence="11">1.3.5.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">DHOdehase</fullName>
            <shortName evidence="11">DHOD</shortName>
            <shortName evidence="11">DHODase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Dihydroorotate oxidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">pyrD</name>
        <name evidence="13" type="ORF">ESY86_06645</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 11">Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>(S)-dihydroorotate + a quinone = a quinol + orotate</text>
            <dbReference type="Rhea" id="RHEA:30187"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
            <dbReference type="ChEBI" id="CHEBI:30864"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.3.5.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="11">Binds 1 FMN per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 11">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; orotate from (S)-dihydroorotate (quinone route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 11">Cell membrane</location>
            <topology evidence="3 11">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 11">Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.5.2" evidence="11"/>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00946"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004152">
        <property type="term" value="F:dihydroorotate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04738">
        <property type="entry name" value="DHOD_2_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00225">
        <property type="entry name" value="DHO_dh_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005720">
        <property type="entry name" value="Dihydroorotate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012135">
        <property type="entry name" value="Dihydroorotate_DH_1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005719">
        <property type="entry name" value="Dihydroorotate_DH_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001295">
        <property type="entry name" value="Dihydroorotate_DH_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01180">
        <property type="entry name" value="DHO_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000164">
        <property type="entry name" value="DHO_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01036">
        <property type="entry name" value="pyrD_sub2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00912">
        <property type="entry name" value="DHODEHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7 11" id="KW-0288">FMN</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9 11 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8 11" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHO_dh" evidence="12">
        <location>
            <begin position="50"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="11">
        <location>
            <begin position="116"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="11">
        <location>
            <begin position="246"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="11">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="67"/>
            <end position="71"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="176"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="217"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="267"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="296"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="317"/>
            <end position="318"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TXD89875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="344" mass="38294" checksum="64C7A0375892DDD7" modified="2019-11-13" version="1">MYKSVIRPLLFRFDPEKVHYFTFSMLQKVFKIPGAQSFFRSNYLIEHKSLERELFGLKFKNPVGLAAGFDKDAKLYNELSSLGFGFIEIGTLTPKAQAGNPKQRLFRLKEDQAIINRMGFNNAGVAEAVERLKKNKNVLIGGNIGKNKVTANEDAVEDYRICFNALFKYVDYFVVNVSSPNTPNLRALQDKAPLTALLNELQVENAKQERQKPILLKIAPDLTDSQLMDIIDIVADTKIDGVIATNTTIARQNLQSEHKAEMGGLSGKPLTNRATEVIRFLAEKSNKAFPIIGVGGIHSAADAMEKLEAGADLLQLYTGFIYEGPQLIKDINKAIIKKANQDKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIA9</accession>
    <name>A0A5C6ZIA9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2183 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06975</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008195">
        <property type="term" value="F:phosphatidate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019236">
        <property type="entry name" value="APP1_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09949">
        <property type="entry name" value="DUF2183"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2183" evidence="1">
        <location>
            <begin position="180"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="322" mass="36974" checksum="9C38D982BD94FAD8" modified="2019-11-13" version="1">MKIDISVYRGYVNEKELVLSGHVFKSWAPSQYSIQKRAFKHAFAIFKMFSIKPLKNIPVSLEFQGIKTTTKSLDDGYFSFRIPFTQKLESGWHNCSVICKANTYNIVTTGEILKPFDGMYGIISDIDDTFLISHSSNFFKKLYVMLMQNIDKRQVFEDVSEHYQALSLAGQDGHQLSNSFFYVSSSEWNLYPFIIAIANKYQLPKAVIKLKKIKTGIGDFLFTGRGNHDHKFNKIKDIISFYPLSQYILLGDDSQKDPYLYEQICKLFPENIKAVYIRQTGKHQKEAVTGILQNISSLKPETLYFTESKSAIAHSKRIGIID</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIB3</accession>
    <name>A0A5C6ZIB3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HigA family addiction module antidote protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_07115</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010359">
        <property type="entry name" value="IrrE_HExxH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013430">
        <property type="entry name" value="Toxin_antidote_HigA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36924">
        <property type="entry name" value="PTHR36924"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06114">
        <property type="entry name" value="Peptidase_M78"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02607">
        <property type="entry name" value="antidote_HigA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="2">
        <location>
            <begin position="34"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="364" mass="42646" checksum="62276EDE7875C857" modified="2019-11-13" version="1">MATQKVLTPAQATHPGVLIKDELDAIPDLNQRILAKELDVHPSFLNEIIKGKRPVTADIAILLEKIFGISADYWMKFQSQYEIDKARVKQKNIKKVRNIELWSIIKEYVPVRYFKKHHYLNDDLERDIKTIMNIYEVETIDGLVSSFSNDRFAYYRKSNKLKIDDKNMFAWSSLAQYEAKNQKTNTFNFDNLNQLCKNLNNIFYENSGTPKRVKSVLNQFGIKMLLIDKLEKTPIDGFSFWSDKNPAIALTLRYNRIDNFAFTIIHEIGHIDLHLRNDKDIKFMDLTSKQKLDKCETEADNYAHQKLIPNDIWQDILDNHLPLNDDKIKDLGDKHRIHPAILLGRVCYEGDYYAMKTTIDKKMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZID3</accession>
    <name>A0A5C6ZID3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PhnA protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013991">
        <property type="entry name" value="PhnaA_N_proteobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004624">
        <property type="entry name" value="YjdM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013988">
        <property type="entry name" value="YjdM_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30305:SF3">
        <property type="entry name" value="PTHR30305:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03831">
        <property type="entry name" value="YjdM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00782">
        <property type="entry name" value="PhnA_Zn_Ribbon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PhnA_Zn_Ribbon" evidence="1">
        <location>
            <begin position="6"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="192" mass="21906" checksum="E415F8AA3386BD7A" modified="2019-11-13" version="1">MSVLQTLQDRSNNACELCASKENLSQYTIPPSLNENVANDLLVCKTCRDQIEVNTAMDPNHWRCLNDSMWSEHVAVQIMAWRMLQRLRNEGWPKDLLDMMYLDDEALALARETGEHEEEANKIIHRDANGVILEHGDSVVLVKDLKVKGSSMVAKQGTAVRNIRLDRDNAEYIEGKVDNQQIVLITQYVKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZID9</accession>
    <name>A0A5C6ZID9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_09435</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="241"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="400" mass="45679" checksum="188E89441BB34605" modified="2019-11-13" version="1">MLQNIWTYLKYGNRFCGMEHTSTNGKDQINCIVLKRTKKELVVADLCQTDSFEEVSKKLSRNQHAVLTVNNDQVLFKSINSNESEASKLVYKAFPNIQMEAFYYEVISEGSQHFVSICRKTFLDSLIDIYARNHVYVIDISIGNAMISNIKSFLKVDTVRTSNAIIAIENNVIKSIEKSDTENELYNVNGLEVSNKEILSLAGALKPILNSDTSISNFNDKRKAILADFGQVRFFNQFFKFSGLFLLSILLINFFIFNHYFNKVNELKQISQINQSTKEQILGLNETVTKKQKTVDDLLNGNASQTSFYTNVVMQSLPNSILLSEFNYQPLKKRIKADKDIELEYHIVQLSGTSTNSDVFSKWIGEMEQLDWITSIEILEYGLKNSTSSNFKIKAFIAHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIK6</accession>
    <name>A0A5C6ZIK6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_10260</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="2">
        <location>
            <begin position="117"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="399" mass="45463" checksum="AC38AC373ECF6E6E" modified="2019-11-13" version="1">MSKQALNFLCITTYFKGEDFLKSCKADGNKVFLLTKKKLEHKAWPWEAIDDVFYIDDWVQSDITKGIAYKLRTLKFDRFVALDDFDVEKVALLREHFRMPGMGRTTAHYFRDKLAMRMKAQEEGVNVPEFTSLFYNEDINAYAERVEAPWLLKPRMEASATGIKKIYSKDELWPIIDALGDERDNYLIEKFAPGDVYHVDGLNLEGKVIFSRVSKYLDTPFEVAHGGGIFRSASCEVGTKTEKGLQKMNAQVMKAFGMQFGASHTEFIKSKATGELFFLETSSRVGGANLAEMVEAASGINLWGEWAKIESANLRKTTYKLPKLKHKYAGIVVSLSRYEHPDTSSFNDDEIVWRMHKEWHIGLIVASDSSERVLELLKQYSQKIASEFHASLPAPDKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIS8</accession>
    <name>A0A5C6ZIS8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">M1 family metallopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_04855</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022736213" evidence="1">
        <location>
            <begin position="24"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M1" evidence="2">
        <location>
            <begin position="353"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="644" mass="72999" checksum="D31F4994CF458F3C" modified="2019-11-13" version="1">MTYFKNSILLGLLAVACSFSISAQEAKPDNQHLFDDFSYRKGNVYRTASGKPGPEYWQNAADYDLEVTLDDKTHSVTGRVTIKYTNNSPETLDFIWLYLEQNRFTQNSRGTLTTPIRGNRYNGDVEGGFELANVSAQTKTGTSSKYLITDTRMQIFLDQPLEAKGGEVTLKMDFDFKVPVEGMDRMGRLDTKEGTIYAIAQWYPRVAVFDDVVGWNTEPYLGAGEFYCEYGNFDVKITASANQTVVCSGVLQNPKEVLTNTQQKRFAEAEKSDATIYIIKPDEVGTPISQAKTRGTQTWHFKMENTRDVAWAASSAFIWDAARMDLGNGKTGLAQSVYPIESDGNSAWSRSTEYTKESVEFYSETFFPYPYHNAINVAANVGGMEYPGVSFCSFESTNADLWGVTDHEFGHNWFPMIVGSNERRYPWMDEGFTTFINHYSSKAFNNGEYPSATGSPRNLVRYLTYDQREGIDTSPDVANARNLGYTAYYKPAAGLYMLREYILGAERFDNAFKSYINYWAYKHPQPNDFFNHMENVAGENLSYFWKGWFYGNGNIDLGIASVEAYQDNYLLTIENSGQIPMPVELLVIYTDATTENVSLPVEIWQRGNSWSHLFKTDKTIQRVVLDPNKLLADINILNDSWNKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIT2</accession>
    <name>A0A5C6ZIT2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Sigma-70 family RNA polymerase sigma factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_05160</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="259" mass="30486" checksum="188031A7B4425AB2" modified="2019-11-13" version="1">MKNTETYSQKSNFRIVVEHTYLKLVKSKKQDDKVTFNQQLLKILPEVKKYINGRLNTAIKKGHFSKGKYKADDFSDQLFIEIYDHIETIKDEKDFYLWVFKKTNELLEDTIIEEEFDDLFFQNIDDYSKPEWDAMQEKFSTDGDGDLLMIEELDDSSYNHNDYTLNHVFIENDEKEMTEKLDKDLSEEAVNLHIQMVLHNLPVSMRTVFELSTQQRLGINEIAQVIDSTVKEVEQLLKDARNALQISLFNRCSTKATND</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ08</accession>
    <name>A0A5C6ZJ08_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Photosystem reaction center subunit H</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_06745</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030077">
        <property type="term" value="C:plasma membrane light-harvesting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045156">
        <property type="term" value="F:electron transporter, transferring electrons within the cyclic electron transport pathway of photosynthesis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019684">
        <property type="term" value="P:photosynthesis, light reaction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.50.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014747">
        <property type="entry name" value="Bac_photo_RC_H_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011033">
        <property type="entry name" value="PRC_barrel-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50346">
        <property type="entry name" value="SSF50346"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="168" mass="19241" checksum="AA511F508563F8F7" modified="2019-11-13" version="1">MGTDKERNLYYLEELSDYKVADSDMDVRGWEVKDKDERVIGTVDNLLVNKSTERVVYLDIEVDASIIEANHKPYNIREKDGVHGFLNKDGENHLILPVGLAQLHLESELVSTENINHKTFAETKRIKKGTAIDRDYEVVVLDSYVRSDEAKAYPKDDKFYQSEAFGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ15</accession>
    <name>A0A5C6ZJ15_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">T9SS type A sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_06810</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022711997" evidence="1">
        <location>
            <begin position="20"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="domain" description="Por_Secre_tail" evidence="2">
        <location>
            <begin position="463"/>
            <end position="521"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="523" mass="56101" checksum="FDD3B64380E1F4E9" modified="2019-11-13" version="1">MKNYYLILCSVAICLSANAQELSTTMTVKPGSTVYVSSGTTLAPSNLNLKSRSNSYAILLLKGDLGASTIVNYDRHVNKVGQSGVNGGNDLISMPVKVAGDATFVEFLDYSNGSDINSDVLANSTTLYAFGPYNNSNQSYTNYDAVANAAALLERGVGYRAAATNSGQTLRFTGTVSTVTETVEISTSNNYWNGVGNPYPTFIDSQKFLTENSIALDPNATAVYGYNSGTNPEVGSGTFGNFTVINNLTNTDVNIAPGQGFLVANAPDNATHQINFTTAMQTSAGTDDFILGRTDNEVQKLRLRAQHATGDFATEIYFNGNSTLGLDPGYDAALFNGVGGDFFLYSQLVENNQGRNMAIQSLGSNDLNDITIPLGLKTAQGKQVTFSIETSTLPETIDVYLEDNQTNTFTLLNASEYTFTANSNISGTGRFFLRIGNSTLSNIVPENGSLQIFASKQTLFVNGPLLSETKVSIYDIQGRLVMTSFLDEASDLNKIDASALNTGIYVVKLNNEAQQQTKKVIFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ39</accession>
    <name>A0A5C6ZJ39_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_09075</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="80" mass="9363" checksum="F7436756E4B4CD21" modified="2019-11-13" version="1">MHKYNRQNFFKLPFCEYIIKANSGMKGMSRPCCYRPNCFSHKFSVFSLPSSVFRLPSSVFRLPSSVFRPLKSTPFTFKPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ51</accession>
    <name>A0A5C6ZJ51_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Probable beta-carotene 15,15'-dioxygenase</fullName>
            <ecNumber evidence="1">1.13.11.63</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the cleavage of beta-carotene at its central double bond (15,15') to yield two molecules of all-trans-retinal.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>all-trans-beta-carotene + O2 = 2 all-trans-retinal</text>
            <dbReference type="Rhea" id="RHEA:32887"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:17579"/>
            <dbReference type="ChEBI" id="CHEBI:17898"/>
            <dbReference type="EC" id="1.13.11.63"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Brp/Blh beta-carotene diooxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.13.11.63" evidence="1"/>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003834">
        <property type="term" value="F:beta-carotene 15,15'-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010436">
        <property type="term" value="F:carotenoid dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016121">
        <property type="term" value="P:carotene catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02093">
        <property type="entry name" value="Beta_carotene_diox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022270">
        <property type="entry name" value="Blh_monoox"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15461">
        <property type="entry name" value="BCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03753">
        <property type="entry name" value="blh_monoox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="1" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="156"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="189"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="246"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="269"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="300" mass="34615" checksum="1E9BCBF775A0AAA3" modified="2019-11-13" version="1">MTVKTRNISIVSSFVCLWLASLLASDLETVCGFILIFSFGILHGANDLLLFDKMALRKGKSTHFIILAIYIGLVILVFSLFLVIPLWALSVFIVFSAYHFGEQHWERSTLNSPVWIKKLFFGIYGLFVLALLFVLNATEVLQIVYSISSYQFSPKILEYGFIIISLMFLAITGYLAFKQKNFRKNGIEELLYLLVFSIIFKISSLIWGFAIYFIFWHSLPSLYDQITFVYKDFNTKNALAYTKAAFPYWLISVVAMVAFYFVFKSMDIFYALFFSFLAAVTFPHTFAIHTMFKRIRKGNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ56</accession>
    <name>A0A5C6ZJ56_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_05490</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="106" mass="11973" checksum="B806FF1A139C5EA6" modified="2019-11-13" version="1">MNSYLKNTISLFFLTTFLLLKVVNLHEVSHITSDKDTQHCEQCAFIAQAGQTTPLNVPTPQENISFVNPFDFVEHSAAYTLYVAPHQKVLHSDYFHNKPPPNSLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJA1</accession>
    <name>A0A5C6ZJA1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_06545</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002656">
        <property type="entry name" value="Acyl_transf_3_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01757">
        <property type="entry name" value="Acyl_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="210"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="242"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="267"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="307"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="334"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl_transf_3" evidence="2">
        <location>
            <begin position="10"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="378" mass="44528" checksum="DD53378004A23D43" modified="2019-11-13" version="1">MPIDYSKRIYGLDVVRAVAILLVMLSHSTFLIFPNGGHPIISIFQFFGAIGVDLFFVLSGFLIGGLLLRQIEQQKVRFKDVFYFWIRRWFRTLPNYFLILLLNILMIYLLFGIIIDQIGDFLLFIQNFSAPHPNFFTEAWSLSIEEYAYLIGPLLLFLLVLIFSKVNKFRLFLVTTLLIIVGVSMARYRFGLSHDYVDYSDWSQHIRKVVIFRIDSIYYGFIGAYVAYTFKSFWETHRIKLFFTGALLFITVHACILLFQIQPQHANLFYTVFYLPLVSVSILLLFPLCSSWRDRTIFEKQITKISILSYGLYLVNLSLILLPLQLWLKSMTTSIGFNFVILAVYWVLSFVFAQLLYRYYEKPMTDLRDSRRIKSYFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJB1</accession>
    <name>A0A5C6ZJB1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Anti-sigma factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05880</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018764">
        <property type="entry name" value="Anti-sigma_K_RskA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10099">
        <property type="entry name" value="RskA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="266" mass="30358" checksum="6982115A7DEA756B" modified="2019-11-13" version="1">MENKLHTFLQSDMLERYVLGNTSALENLKVESYIEMYPEVELAFEEMQINLEILAKSNAVVAPKHVLENVKKVIEVDNTPVITLTNDRRRTPWYSIAASITALLFAGASFLMHQKNLDLQHENQVVVDEVFDLRSDIDANNKKLDEVMRQFKDLNNPETEKYVMRGNSRAKNLKTVAYINPVDKTSMIDVVTLPQINDNEDYHLWAEMEDHFVSLGILNPAEKKMQSMPYMENALGLSITIEPKGTKNSNSDNAVAEIELNNNKNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJC4</accession>
    <name>A0A5C6ZJC4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">S9 family peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_09285</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110165">
        <property type="term" value="C:cellular anatomical entity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002471">
        <property type="entry name" value="Pept_S9_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002469">
        <property type="entry name" value="Peptidase_S9B_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00930">
        <property type="entry name" value="DPPIV_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00708">
        <property type="entry name" value="PRO_ENDOPEP_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022843752" evidence="2">
        <location>
            <begin position="21"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="domain" description="DPPIV_N" evidence="4">
        <location>
            <begin position="96"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9" evidence="3">
        <location>
            <begin position="528"/>
            <end position="724"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD89230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="733" mass="83427" checksum="9DA1B0AA6F460954" modified="2019-11-13" version="1">MKLLKSCTVLFLLVSTLASAQKKEITLEDIWTGSFRTERMGGLHSMNDGQQYSVLDFSNGTSQIDIYDYKTLTKQKTLVNSANIDSIGYFSSYTFSEDESMVLLATDVESIYRRSTLGKYYIFNSKTNQTTLVSEEKIQEPTFSPDGTKLAYGLNNDIYVKDLTTGQTNQITKDGKKNEIINGVTDWVYEEEFSFVRAFEWNAASNKIAFIRFDETDVPEFSMDVYGQELYQTQQVFKYPKAGEANSLVSLHIYDLESASTKEVSLDKTYSDFYIPRIKWTNEPNVLSAQYTNRHQNELDVWFIDAETLKGDLVLAETDKAYIDVTFNLTFLKDNSFIWTSEKDGYNHIYHYDKTGTLINQVTSGNWEVTDYYGYDEKSKRIFYQSTEDGSINRAVYAIGLNGKNKQKLSEKTGTNSADFSADFSYFINSYSSATVAPEYTLNNAKTGKVIKPIKNNEALQQKLKGFNISSKEFSTISINGNDLNMWMIKPSDFDETKTYPLFMYQYSGPGSQEVSNSWNSANDYWYELLAQKGYIVACIDGRGTGFKGADFKKVTQNELGKYELEDQIAAAKKLGQLEFIDADHMGIWGWSFGGYLSSAALFKGNDTFSMAIAVAPVTSWRFYDTIYTERYMTTPQENASGYDDNSPINFVDGLEGDFLLVHGTGDDNVHVQNTMRLVEALIQANKDFEWMLYPDRNHGIYGGNTRLHLYKKMTNFIDKTLGEARPEAYKEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJG4</accession>
    <name>A0A5C6ZJG4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transglutaminase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_11110</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002931">
        <property type="entry name" value="Transglutaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01841">
        <property type="entry name" value="Transglut_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022970358" evidence="1">
        <location>
            <begin position="19"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="domain" description="TGc" evidence="2">
        <location>
            <begin position="281"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="638" mass="73496" checksum="87AD883FECD8A6CA" modified="2019-11-13" version="1">MNYPKLLLVLLISTSAFSQGKVEPTPEDLEIANVLKTEFPDDEVALISSVDLITFDFDKKNMQVTVKQITDEEMINLDSRADIQKYCFYDGESEITEFEISYINGKKAGFQINDEAYKSDDLFHNDSRVQYADMDFPLNAYRYLTHVKKEYKDVKYFTSLYFNDDYPIQKKTISVTIPDWLNLELKEMNFEGHDIEKTLTTEAENHTKTHTYTLNNVPAMYQESNAPGPSYIYPHLLILAKSYTRDDTSVTLFDATKDLYGWYISLVNSLQNDNSALQAKVNELTESAKTDDEKIKNIYYWVQDNIRYIAFLDGIAGFKPDEAANVFNKRYGDCKGMANLTKQMLLEAGFDARLTWIGTKHIAYDYSTPNLAIDNHMICTLFKDGNTLFLDATEKFNALGEYADRIQGKQVLIENGEDFILQYVPQAKASFNKETLSYNLTLEEDHIIGSVDRHYNGESRSQLLQNFHTLKTENKAEFLEFYLNQGNSNIAVSNIDTTNLLNRDQNIDIAYDVAIKNAVSSFDGQIYIDLDFDKELATHKMEKRKTDFIFSSKKDLESVTRLQIPSGYKVSHVPANISISSDNYDMQVMFKKEDRALVYKKQFRIKNAKVATSDFEQWNQFIDQLNALYNDQIILSKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJU4</accession>
    <name>A0A5C6ZJU4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_06415</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808">
        <property type="entry name" value="PTHR11808"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="399" mass="43348" checksum="1052F77CC6C25234" modified="2019-11-13" version="1">MAFKPANNIQDLQYFGEFGGVNPSISDSSTYTFLSAKTMFDTFEGNADGCYLYSRHSSPSNLYLGEALAAMEGTETANVSASGMGAISPVLMQLCGAGEHIVSSRTIYGGTYAFLKNFIPRFKVSTSFVDITNLEAVEAAINKNTKVLYCESVSNPLLEVADIKGLAEIAKRHHLQLVVDNTFSPLSISPAQLGADIVIHSLTKFINGSSDTVGGVVCGTQEFINELRSVNDGASMLLGSTMDSLRAASVLKNLRTLHIRMQQHSHNANYLAEKFEHDGLKTVYPGLASHPSHQLFKSMMNEKYGYGGMLTIDVGSLDKANALMEMMQNENLGYLAVSLGFYKTLFSAPSSSTSSEISEEEQAEMGLSDGLIRFSIGLDADIERTYQVMRSCMEKLDIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK36</accession>
    <name>A0A5C6ZK36_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07885</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="263"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="291"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="346" mass="40235" checksum="80F830C9E918A04B" modified="2019-11-13" version="1">MAYSENLVFGLKRINVFLPVSFLPAVILSEKLNNKMIQSVLNILKYWVIAVFSYYIILHVFIDERVLSTFVPYVMNDRLGISQFYILFIVLIPFLKSINDIFQRKRLILNIACCCFFTFCILLLANKTALVILLAFTIFKTFNALKQYNKITVSLSAVAIITILVGVIYMTPNLKKRIDVMIKTVDFDIETIITKNSVTFTKNTLEHRLLINYIAISEIKKSFPFGVGIGDTQDVLFSNYKKINFKQGIRNNFNNHNQYIDEFLKSGIFGGFYFLFLMFSLIKLGSVRDQFYSFITIFFAFSCLFESYLFRQHGIIIFSFMIPLFLKYDEQLRVSKEPISNELDIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK40</accession>
    <name>A0A5C6ZK40_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">LysM peptidoglycan-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_04190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="SSF54106"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LysM" evidence="1">
        <location>
            <begin position="22"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="1">
        <location>
            <begin position="85"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="1">
        <location>
            <begin position="147"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="635" mass="72366" checksum="D90A5059D9B067B6" modified="2019-11-13" version="1">MKKLIIIITLFFSVVAIGQNYKTHMVTNGETIESIAKKYKVSTNELYALNPDAKTNFNQDMILIIPDGNADAGEVKETRAFVDYKKHRVKRKETLYGIAKEYGISVDDIKKHNTRLYAENLQKGDKIQIPRFKTVTTQEVKVNNTIRKYKVQPKEGVWRVAYKFNISVAQLESLNPDMGLILQPGQELNVPNIDNKDEKRFEEDYNYYTVLKSEGYMALNRKLGVTQEELEAINPELKEDGLKLGMIIKVPKTSKTTLVVEDIVNTNLSSKLTNFKEKKIAVMLPFRTAKLNLDAIDETKKKIRTDALLSASLDFHAGVLMALDSAKQLGISTHLKVFDTQNLSTEVAKILRDNDFSDYDAIIGPMLSENLNQVASELRKDNIPVLSPLTMPINLFDNVYQTIPSSELLVQTMINFVKSDTQPKHVVIISDSKNKVISDKLKGEFPSAKQVFSRNDKEGKEAYYINQNDLVNVFRTGRNIVFLETMNEGFASNVISMVNGMSTSSTQIILMTTDRNKAFDGREISNYHLSNLKFHYPSPNKTTDISSTINPFVRDYRRIYNVSPNKYAVRGFDLTFDLLLRLASADDLYQASSEDIETEYFENKFRYAKKMYGGYYNEAVYIVKYEDLTIVEAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK64</accession>
    <name>A0A5C6ZK64_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Porin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_04290</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023614">
        <property type="entry name" value="Porin_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010870">
        <property type="entry name" value="Porin_O/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07396">
        <property type="entry name" value="Porin_O_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022702802" evidence="1">
        <location>
            <begin position="20"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="400" mass="46129" checksum="BBAA6A5E7C4335AB" modified="2019-11-13" version="1">MKNLFFCLMVLLVFSSVKAQDNNDIKLSALPYYNYGKGLGITSADSIFQLNIRFRMQNRVTYLRNDDEDPAYEALIRRLRLRFDGYVGDPKIIYVIQLSFSPGDVGAIENGENINIIRDAVVFYRPNKHWNIGFGQTKLPGNRQRINSSGALQLTDRSINNARFNIDRDFGLQIYYLNELETKFSYNVKTAISTGEGRNWTREPDNGLAFTGKLELFPLGSFQSNGTFFEGDLKREDRPKIMISGVYHYNEKARRNQGTLGNELFERRDLKSLFVDTVVKYDGWAFQAAYMKRMADDPITINPNDSNNLEYAYVGDGFDTQLSYLFENNYEVIGRFSHQTPNAKIASLTPQANQYTLGVTKYIWEHALKLQAEVTRTDLNYFDTTHAENWYLRFQVEIGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKA0</accession>
    <name>A0A5C6ZKA0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Rhodanese-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_01965</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="19"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="103" mass="11576" checksum="94FB8F8A103BBF3A" modified="2019-11-13" version="1">MGVLELLFGSKKKRIKAFLDKDAVIIDVRTQQEWDKGHIKTAKHVPLHLLKDKVSELKALNKPLILCCQSGVRSVKAAKYLQMHNLEATDGGGWRSLEKIVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKA3</accession>
    <name>A0A5C6ZKA3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sigma-54-dependent Fis family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_05705</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025662">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025943">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01590">
        <property type="entry name" value="HTHFIS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00675">
        <property type="entry name" value="SIGMA54_INTERACT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00676">
        <property type="entry name" value="SIGMA54_INTERACT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="5">
        <location>
            <begin position="13"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD90232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="422" mass="48297" checksum="70ED33329408A746" modified="2019-11-13" version="1">MDSIQAIKQRFGIIGNDPKLNRAIEKAIQVAPTDISVLVTGESGVGKESIPKIIHQLSHRKHGKYIAVNCGAIPEGTIDSELFGHEKGAFTGATNTRSGYFEVADGGTIFLDEVGELPLTTQVRLLRVLENGEFIKVGSSKVQKTDVRIVAASNVNIFEAIKKERFREDLYYRLSTVDINIPPLRERKEDIHLLFRKFASDFALKYKMPTIKLTDDAVNALVKHRWNGNIRQLRNIAEQISVLEQKRSIDAKSLNDYLPNASNNLPAVVNNSKSESDFSNEREILYKVLFDMKSDLHDLKKLTMELIKSGKDDNVEKDHEGLINKIYGERKKEDYEEDFEDLEVLSIPEKFEQDIEDLEEKQKDKYYFAEEIEEEETLSLHDKELELIKKSLERHEGKRKLAAAELGISERTLYRKIKQFDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKH7</accession>
    <name>A0A5C6ZKH7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_07735</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="67" mass="7486" checksum="88317F0D8CCAF70F" modified="2019-11-13" version="1">MKKNQIALPIDKINSSSMFSYGNKKIPDNFASGIYLVFLRISFQILIRAAVAAIEKFALSQLSHLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKN1</accession>
    <name>A0A5C6ZKN1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyl-CoA carboxylase subunit beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_03225</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034733">
        <property type="entry name" value="AcCoA_carboxyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011763">
        <property type="entry name" value="COA_CT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011762">
        <property type="entry name" value="COA_CT_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01039">
        <property type="entry name" value="Carboxyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50989">
        <property type="entry name" value="COA_CT_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50980">
        <property type="entry name" value="COA_CT_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CoA carboxyltransferase N-terminal" evidence="1">
        <location>
            <begin position="1"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="CoA carboxyltransferase C-terminal" evidence="2">
        <location>
            <begin position="260"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="513" mass="56253" checksum="3C963A25409D609C" modified="2019-11-13" version="1">MKSKIEDLNKKLKEAHLGGGQARIDKQHDKKKLTARERVMYLLDEGSFEEIGALVTHRTKSFGMDKQLFYGDGVVTGYGTVNGRLIYIFAQDFTVFGGSLSETHAEKICKVMDLAVKVGAPIIGLNDSGGARIQEGVRSLGGYADIFFRNVQASGVIPQLSAIMGPCAGGAVYSPAMTDFTLMVENSSYMFVTGPNVVKTVTNENVTSEELGGASTHSTKSGVAHKTSINDIECLEDLKSLLSYLPQNNKETATHLPYELGDEFREQLSDIIPDNANKPYDMHQVINGIIDADSFYEIHKNHAENILVGFARLGGRSIGIVANQPMFLAGVLDVNSAKKAARFVRFCDAFNIPLLVLEDVPGFLPGTDQEWNGIIVHGAKLLYAFSEATVPRVTVITRKAYGGAYDVMNSKHIGSDMNFAWPSAEIAVMGAKGAAEIIFKKEINKADDKEAKWKEKEAEYAELFANPYSAAERGFVDEVILPKDTRRKLIKAFSMLENKVVTRPDRKHGNIPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKU9</accession>
    <name>A0A5C6ZKU9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase family 4 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_04515</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="182"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="359" mass="41597" checksum="9A5774E8DAC6E451" modified="2019-11-13" version="1">MKNILLEAHNISNLHFGFGQFNFHLLQALSKQEALLNDEAIRLTVLGKNPSDLKAKFSTDFIYKKYHSLQRKPFFRIRKKYELWHSLNQNTKVEPYHKIPYLLTVHDVNFMEEDQGEKLKKRQQLFKEKLERSDAITYISNYAKSMTHCYFEVPNVPEYVIYNGSPNKAVAIAEDYQPKILPGQPYLFSIGEFLEKKNFHTLLEMLIHLPDLSLVLAGKDTTAYADRIREKVKTLGLQNRVLITGKISEQDKNYFYQNCSAFVFPSLREGFGIPPIEAMTYGTPVFLSNKSSLPEIGGALAYYWEHFDPKYMAEQLNQGLAHFESNKSELPAKLIAHAKSYSWDKAASRYIEVYKTLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKZ8</accession>
    <name>A0A5C6ZKZ8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Long-chain fatty acid--CoA ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020459">
        <property type="entry name" value="AMP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00154">
        <property type="entry name" value="AMPBINDING"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-binding" evidence="1">
        <location>
            <begin position="14"/>
            <end position="458"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="589" mass="67323" checksum="E13988C8F69F65BD" modified="2019-11-13" version="1">MTDIKRLFDFPYYQLEHKPSDTALVTKYNGVWTPMSTQEYVDKSNAMSRALLRLGIKKDDKIAIISTSNRTEWNIMDIGILQLGAQNIPIYPTISAEDYEYVLNHSECIYCFVSDKDVLEKVRAVQSRTKLKEVYSFDVIEGCKNYSELFELGKDESNQPEVEAHKDAVKPDDLATIIYTSGTTGRPKGVMLSHWNITSNALDSNKRLPLIEGETRILSFLPICHIFERLLIYLYQYAGVSIYYAEGIDKIGDNAKEIQPNLMSVVPRLLEKVYDKIYAKGSELTGIKHKLFHWAIALGEEWKPYGENGWWYEFKLSIAQKLIFSKWQEALGGKLHTMVSGSAPMQPRLTRLFSAAQMQVMEGYGLTETSPVVAVGMYADGNFRVGSVGKPIDNVHVKIAEDGEILIKGPNVMLGYYKDPEKTEEVMTDGYFHSGDKGEIDIDGFLKITGRKKEMFKTSGGKYVIPTLLENELKQSRFIEQVMVVGEGEKMPAAIVQPNFEFIREWIKKKHNNVGTSNKDIVNAKEVIDRIQKEVDKCNTHFGHWEQIKRFELTEDVWSIEGGQLTPTMKMKRDIIKDHYIDLYNRIYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLN0</accession>
    <name>A0A5C6ZLN0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_07295</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="136" mass="14836" checksum="EA959FDF58552F3A" modified="2019-11-13" version="1">MNYRLLILLTLITTAFIGCNDDDPNRIDAVPSISGTWNLSNVSGGFVGTDVDFEDGLITWSFNTETSQVKVINSNADPVAFDGLPSGTYDYVLENNAGVETLKVDYLDMTVNAMSNTQMLLDDGIAYDGFLLSFSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLS7</accession>
    <name>A0A5C6ZLS7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_00090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045470">
        <property type="entry name" value="DUF6495"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20105">
        <property type="entry name" value="DUF6495"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="157" mass="18253" checksum="183A3F2A26B2812A" modified="2019-11-13" version="1">MKYARLTKEQFEELNQEFINFLATQSITAAEWAEIKTNTPEVAEEELDVFSDLIWEGVLSKVQYLEHISPQQMHLFHCAKKELRLIALKIKNPKVDITTTEGFDWFRANLLSDDVEFFTANKAYSENKGRDKFKIIEEGASITKGELYTYFESLVSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLV3</accession>
    <name>A0A5C6ZLV3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_02585</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="63" mass="7456" checksum="E1A294CAA90AEDFF" modified="2019-11-13" version="1">MKLIGIKRFTKTEGRFTKKMGAFTTNVTYIKKHFLSIPFATLHKYRETYYGKVKDCEECKLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLX4</accession>
    <name>A0A5C6ZLX4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Lipoyl synthase</fullName>
            <ecNumber evidence="6">2.8.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Lip-syn</fullName>
            <shortName evidence="6">LS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Lipoate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Lipoic acid synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Sulfur insertion protein LipA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">lipA</name>
        <name evidence="8" type="ORF">ESY86_05860</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>[[Fe-S] cluster scaffold protein carrying a second [4Fe-4S](2+) cluster] + 4 H(+) + N(6)-octanoyl-L-lysyl-[protein] + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = (R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + 2 5'-deoxyadenosine + [[Fe-S] cluster scaffold protein] + 4 Fe(3+) + 2 hydrogen sulfide + 2 L-methionine + 2 reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:16585"/>
            <dbReference type="Rhea" id="RHEA-COMP:9928"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:14568"/>
            <dbReference type="Rhea" id="RHEA-COMP:14569"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:33722"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:78809"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="EC" id="2.8.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="6">Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Protein modification; protein lipoylation via endogenous pathway; protein N(6)-(lipoyl)lysine from octanoyl-[acyl-carrier-protein]: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the radical SAM superfamily. Lipoyl synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.8" evidence="6"/>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00538">
        <property type="reaction ID" value="UER00593"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016992">
        <property type="term" value="F:lipoate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102552">
        <property type="term" value="F:lipoyl synthase activity (acting on glycine-cleavage complex H protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102553">
        <property type="term" value="F:lipoyl synthase activity (acting on pyruvate dehydrogenase E2 protein)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00206">
        <property type="entry name" value="Lipoyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003698">
        <property type="entry name" value="Lipoyl_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10949">
        <property type="entry name" value="PTHR10949"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005963">
        <property type="entry name" value="Lipoyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00271">
        <property type="entry name" value="lipoyl_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00510">
        <property type="entry name" value="lipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="5 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Radical SAM core" evidence="7">
        <location>
            <begin position="58"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="284"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD90261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="292" mass="33256" checksum="9E7F330B4A59D7EA" modified="2019-11-13" version="1">MNTETLSKPIVERQPKPKWLRVKLPTGQKYKELRSLVDKYELNTICTSGSCPNMGECWGEGTATFMILGNVCTRSCGFCGVKTGRPETVDWDEPEKVARSIKIMGIKHAVLTSVDRDDLKDMGSILWSETVKAVRRMNPETTLETLIPDFQGIEKHIDRIIDVAPEVVSHNIETVRRLTREVRIQAKYDRSLGVLKYLKEQGQRRTKSGIMLGLGETREEVIETLHDLRANDVDVVTIGQYLQPSKKHLPVKYFVQPDQFDEYRAIGLDLGFRHVESSALVRSSYKAQKHIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM01</accession>
    <name>A0A5C6ZM01_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_02925</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009722">
        <property type="entry name" value="SdiA-regulated"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06977">
        <property type="entry name" value="SdiA-regulated"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="281" mass="31609" checksum="1D07709072203C89" modified="2019-11-13" version="1">MTKFSYIILAFPILFSACHTGQLNNLLDLPVSLKENSALEYTNQDRLLWTIEDAGNPNALYALDAKGQLTKTIEIENAENIDWEDLASDQEENIYIGDFGNNEKTREHFTIYKVSKPGKAMKRSSAEKIAFTLPSTMESQDFEAFFLYENKFYIFSKGTKETIMISVENSIGDHVAQLVTTSKLDGKDNQITAADISADGKTIVLLNHEKLWKLSKFKADKFFEGTVEIIPFGHTSQKEGIVFITKDEVLISDELKNNNGGNLYHLELKGKKSAEGTNQNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM60</accession>
    <name>A0A5C6ZM60_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">5-methyltetrahydrofolate--homocysteine methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_02175</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003726">
        <property type="entry name" value="HCY_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036589">
        <property type="entry name" value="HCY_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02574">
        <property type="entry name" value="S-methyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82282">
        <property type="entry name" value="SSF82282"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50970">
        <property type="entry name" value="HCY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 3 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 5" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Hcy-binding" evidence="4">
        <location>
            <begin position="1"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="243"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="306"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="307"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="340" mass="37435" checksum="79AA2652D62FA9FC" modified="2019-11-13" version="1">MTNIKEELKKRILVLDGAMGTMLQRYNFSEDHFRGERFKAYPSSLKGNNDLLSLTQPQAIADIHRKYFEAGADIVETNTFSGTTIAMADYNMEGLVYELNYESAKIAKKVASEFTNANPQKPRFVAGSIGPTNKTASMSPDVNRPEYRAVTFNELRVAYKQQVEALIDGGVDLLLVETIFDTLNAKAALFAIEEVKEERQIDIPIMVSGTITDASGRTLSGQTVEAFLTSVSHIPLLSVGFNCALGAEQLQPYLERLSRETDFYTSAHPNAGLPNAFGEYDESPEEMKAFIESYLKENLVNIIGGCCGTNPEHIKAIAEVAANYPPRVPALVSSHLEGTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZME1</accession>
    <name>A0A5C6ZME1_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phage_base_V domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00515</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006531">
        <property type="entry name" value="Gp5/Vgr_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037026">
        <property type="entry name" value="Vgr_OB-fold_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04717">
        <property type="entry name" value="Phage_base_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phage_base_V" evidence="1">
        <location>
            <begin position="359"/>
            <end position="434"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="547" mass="60989" checksum="C52748581ABA680D" modified="2019-11-13" version="1">MPIIPLYETIDLELFINGQNDNLHTSIESLTVEYEVNRIPYAKINLVAGNHFQNNAKAKALAFAISDEIEIKIREDGEMKTLFKGLIEEIKKKMSASGFRVQLECKDIVSRLLTVQEIIPNETFQDRFDRLLSHHSISNTLEIASLGDEQISLVDNLSPWDFIISYLDTLGYLTTIKKGVFSAILSTDLGEVTTELQFGVNIFDLEYRRSSTVASVMIEYWDISDQENKREEVDTEVEGSEGIEVNDLGQTYLTPETINKIARGRAAKNRLSTFSGRVKTFGNLQANYGEYMSFIESGNDFEEQSLLITSEHHSIDENGWKTEYAFGLENSQSYVEFNAFVQSKNESRLGQMNSISGLQIGKVTNLEDDPVSQYRVQVQITSINDSGEGYWARLSSIQAGQNRGGWFVPDIGDEVVLGFFSDNPDSPVILGKLYSDNNIAPFDLNNDNFIQGIVTKEGSHLIFDDEKKSIEAKTAGGNIIVISDDESGIILEDQNGNKIQMDSSGITIESAKDLNLKANMSVTIEGVQNSFKASGIMEIQGSLIQLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMJ0</accession>
    <name>A0A5C6ZMJ0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_02715</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="333" mass="38122" checksum="3E96C0941676AF40" modified="2019-11-13" version="1">MNDNASSSETEESGLTPSYNVASYNFTAQQYWDIYSYLVVEGGCSEEAKDFIEEILNSDPDDNDIVDYELEIFVEITETVAFQEQTCLKAIKDDIVATEKISKLIKKFEPTSPVLHLEWGMFSNTNWGNTGNTGLNANQDTAFINLNSQSLTHVSNIVMVQTIAHEIIHAELYRKLKELVDDYHIISLEEYTELQDNFLGIADFTLRYGNREYTQNIMGDIISWGLYPDLTLAHHNQMAAFYRDTLIDVMKAYDLSKGTTRPNAEEFYEALSWSGLRITSDENGEISQFTDAWKNFKNQVDIDEADIPEALRTYNRYINIIINEYDNNGINCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMJ3</accession>
    <name>A0A5C6ZMJ3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05245</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="112" mass="12657" checksum="6A2908EF7DDEC3C8" modified="2019-11-13" version="1">MKSKIHEYQNKHLAMSKISKLIVTVAIASTFLLSSCRDTKTEATDDHGHEHEADGSHMDEEAVEQEEFQVGKDAMETTKEEHGHEHDADGNHSDHNDSETHKHDDGAEHHEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMU9</accession>
    <name>A0A5C6ZMU9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase</fullName>
            <ecNumber evidence="6">2.3.1.117</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_04545</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.117" evidence="6"/>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90641.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008666">
        <property type="term" value="F:2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.166.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023180">
        <property type="entry name" value="THP_succinylTrfase_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037133">
        <property type="entry name" value="THP_succinylTrfase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14602">
        <property type="entry name" value="Hexapep_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14805">
        <property type="entry name" value="THDPS_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="THDPS_N_2" evidence="5">
        <location>
            <begin position="3"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF14805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD90641.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="271" mass="29513" checksum="551F782DFDFF1923" modified="2019-11-13" version="1">MKQLQQNIEDAWEDRSLLSNEVTIESIRSVIDLLDEGTLRVAEPTEDGWKVNEWVKKAVVLYFPIQKMETLEAGIFEYHDKIPLKRDYANRGIRVVPNAVARHGAFIASGTILMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSGGVGIGGVLEPLQAAPVIIEDGAFIGSRCIVVEGVRVEKEAVLGANVVLTMSTKIIDVTGDEPKEMKGVVPARSVVIPGSYTKKFPAGEYQVPCALIIGKRKESTNKKTSLNDALREYNVAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNP9</accession>
    <name>A0A5C6ZNP9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF1573 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_01765</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011467">
        <property type="entry name" value="DUF1573"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07610">
        <property type="entry name" value="DUF1573"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="125" mass="13443" checksum="FD0AD7EF6C2BBADC" modified="2019-11-13" version="1">MSSMMMAQTETIEKAATNDVLGVLSFENETIDYGTIQQNADGVRIFKFTNTGEAPIVISKVKSSCGCTVPTYPKTAILPGETSEISVKYATNRIGAFKKTITITSNASEANKILRIKGNVLKSDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZP38</accession>
    <name>A0A5C6ZP38_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Acyloxyacyl hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_02160</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018550">
        <property type="entry name" value="Lipid-A_deacylase-rel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09411">
        <property type="entry name" value="PagL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="365" mass="42235" checksum="7E52AD56DBC9F859" modified="2019-11-13" version="1">MKRFLSVLLFFCGLLSFSQDKDPNIFNVDASYFYGTILEHNPDISHLITAHPTGLMLSFNKKTYGFKAWESRYNYPDWGFSFIHQDLKNHYLGENYSVYAHFNFYLLKRNLNFRVGQGLAYATKPYDKETNFVNNAYGSDFLSTTYIMLNYKKENIFEGFGLHGGVSIIHYSNANVKAPNNSTNTFVFNVGANYLFNHEKEPDYIASTEEKKFTEPVKYNFVFRAGINESDVIGTGQFPFYNLSMYADKRLNRKSAIQVGTDLFFATFLKELIYFYSVGFPELDVSGREDWRRWGIFVGHELFINKTSLITQVGYYAYYDYDFEGRVYNRIGLKRYFSDTVFGAITVKSHGAKAEGVEFGIGVRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPE4</accession>
    <name>A0A5C6ZPE4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">30S ribosomal protein S21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpsU</name>
        <name evidence="6" type="ORF">ESY86_02705</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the bacterial ribosomal protein bS21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_026754628.1">
        <property type="nucleotide sequence ID" value="NZ_VORO01000002.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00358">
        <property type="entry name" value="Ribosomal_S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001911">
        <property type="entry name" value="Ribosomal_S21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038380">
        <property type="entry name" value="S21_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01165">
        <property type="entry name" value="Ribosomal_S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00976">
        <property type="entry name" value="RIBOSOMALS21"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00030">
        <property type="entry name" value="S21p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD90886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="64" mass="7844" checksum="8EDC889D6671021B" modified="2019-11-13" version="1">MIKILVKDGESIERALKRYKRKHRNVKTMQNIRENQFFTKPSVKRRREIQKAGYIQNLRDQEDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZQ89</accession>
    <name>A0A5C6ZQ89_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_02415</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="226" mass="26003" checksum="0F1B81FDF96CCAC8" modified="2019-11-13" version="1">MKVFETNISILLLVFIQFTGYAQSEHNMINSSIIIPLKTGKNPSSLFEKLVIEPANLFIQSKPINKDSPHIQLELNVFENNTKYTTFLWCYDASSDSEKANYPKAYQNYSFDLKIDKEEVALVVEKLDFGKTMFIDLGQTAVIGKLEILFEDCVGERSEDINGNQTDAFNSYTISLSEEDKQKTVSFMSLNKHEEKALTIEWKHYKIWILEDSEKALKLIVFKKDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6Z979</accession>
    <name>A0A5C6Z979_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">T9SS type B sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_20515</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000082">
        <property type="protein sequence ID" value="TXD86209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026341">
        <property type="entry name" value="Bac_Flav_CTERM"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04131">
        <property type="entry name" value="Bac_Flav_CTERM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="669" mass="70300" checksum="11C2CA0D351994A2" modified="2019-11-13" version="1" fragment="single">TGSFEIRVDLPPVAVLPAPLQLCDDGVADGVTVFDLSVRDSEITGGQGSWAVTYHETLADAQAGQGAVDAQAYTNTAVGGNQANPQTLYAVVTDTDTGCRDITTLTIRVLPNPTPTTELPGLVLCDDTAPGDMAESFDLTENEVLLLNGEDGVTATYHETLQEAESGTAAIADPGGYENSATPQTIYVRVTNDITGCHSTVDFTVRVDPLPKAVALEDFILCELDSDGIGQFDLGSKDGEVLDGQDPAAFTVSYHASQADADALSGSLLSPYTNIANPQRIYVAITNSATGCSVSTPSFEIEVQEGARANPDLGDILYEVCDDGIETDGDPSNDSAQFDLASQDGGILDGQDPMNYSVSYYVSEAAAELGEDPLPLLYENLGNPQVVWARVDNDTPRADGGDSSICHAVAALTLRVNPLPVVALEEYYTLCVGTNGSEVLDAPVLDTGLSAPQYTFVWTLDGAEIAGAGQGSHTATQSGSYGVTVTDVSSSAVTACGSTASAEVVESGPPAITASVTSGAFADLHTVSAETEGIGDYEYSLDGGPWQASGIFDGVSPGAHEVRARDRNGCGLATAAVMVVDYPSFFTPNGDGYNDTWNIVGIDGLQNAKIYIFDRYGKLLKQISPSGRGWDGTYNGGQVPTSDYWFVVEYQEQQAQTTREFKAHFTLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6Z9S3</accession>
    <name>A0A5C6Z9S3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19930</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000052">
        <property type="protein sequence ID" value="TXD86550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="106" mass="12101" checksum="0C69960F90FCD8E2" modified="2019-11-13" version="1">MKKIILILVFAILSCKSNNIKNTEKTENANILDLDTISKIDLDANHLNNNEVQLIYNSIDTISTTLIINKEIISKKEMKAVLDTIRMQNYIVKIDKKGRKIILTSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAA2</accession>
    <name>A0A5C6ZAA2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carboxypeptidase-like regulatory domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20045</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000055">
        <property type="protein sequence ID" value="TXD86505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022957607" evidence="1">
        <location>
            <begin position="19"/>
            <end position="878"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="878" mass="102573" checksum="647A0DDC1ADAFBE3" modified="2019-11-13" version="1">MRYFFLKILLLLCSYSFSQSKIVGNLKSEKKQSISGASITITNLEDADNILNYDISDNEGNFSIILNNKSEKLKLNVKSMGYKSVVRIIDNKSQILDFILEEAVTELKEVVLKSNPIIRRGDTLNYSVNSFVQEQDRTIADVLKRMPGIEVLSDGKILYQGKPINKYYIEGLDLLEGKYNLANENLPHRAVSKVQILENHQPIRILDSLVYSDKAALNIKLKNEYTLTGQAELGSGLTPLLWDANITPLLFTKKQQMLVSYQTNNTGNDAASQLKTLTFEDLLEQFENNTGKQDWLGIQKLSTPNFSEKRWLDNNIHLLTGNYLHKLKRDYEVRLNVSYLNDYQQQNGFTNTSFYTPTDTISLMENKYNQLYLNSLETNLTIQKNTKENYLKNSLQFQGFWDGQIGNIQINGTPLSQNLSNRYFKFSNKFKTIFFLGKQLASLNSYIRLNQTPQTLKVNPGQFEDLLNNGNPYGEVFQEVDLRSFYTNNSLGFTKGWKQFSFSPNVGFQFENQNLESQISTSVNKMLLNAFHNDLDWRRTKLYFDLKTQYKKEKWRVELTTPVNFHRYQIEDEPLQESEELSRLTFEPRLSIIYDANAFWKFNTSASVSNQFGTINQLHYAYILRNYRNIQRINTALPQTFNQTLTAGISYRNPLKSFFWNILYTRTQSENNLLYQTQIMENGVTELQAIEQDNDRTSQNLSTRLSKYFSKLNTNVALNANFGLQDFQQILNEETSDIETQNFGIGGKIETDITDWFNTEYQAKWAFSNNRIQEQSNTTITRQNHLLNLNFYPNENQYFTIKTEYIKNNLFSENTENFFADLVYRYTWKEKNIDFELQASNLFNTKNYRTININEFSYVETNFRLRPRQFLFKVRFSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAE3</accession>
    <name>A0A5C6ZAE3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcription activator effector-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000035">
        <property type="protein sequence ID" value="TXD86900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011256">
        <property type="entry name" value="Reg_factor_effector_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55136">
        <property type="entry name" value="SSF55136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="313" mass="35439" checksum="96A0FD5C2777518C" modified="2019-11-13" version="1">MKAFKYLFFLLLIFVIGFAIYIAVQPNEYNFSRSKIIKAPLPVVFEKVSDYEDWTTWEGKHLRIAAIETIASEENQSITQQFQLSSPLENKATMRYSFEPVPEGTQITWQVEGKYDFANKLNIAMSGKLEDAIAPDLEEGLDRLDRIVRAEMKKYSISIDGITQHSGGFYLYTTGSVKMDDFTNKRETMIAKIKDYAIANAVSMAGPAFVMYLKKDELNDAVIFSACVPTTSQVMSSESDILTGQLEPFKAVKTTLKGDYQYLEEARLKTFNYIEKNELVPLPDGPQLDVFINDSKSVPNPAAWLTEIYIAIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAH9</accession>
    <name>A0A5C6ZAH9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_20455</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000077">
        <property type="protein sequence ID" value="TXD86252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05483">
        <property type="entry name" value="retropepsin_like_bacteria"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021109">
        <property type="entry name" value="Peptidase_aspartic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034122">
        <property type="entry name" value="Retropepsin-like_bacterial"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50630">
        <property type="entry name" value="SSF50630"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="400" mass="45707" checksum="1C9FD4CCEB3818EB" modified="2019-11-13" version="1">MNSKLLIIVSLLIFIKTYSQQTINANQGFVENKEYFSKMKYENKNGKIIIKVSINQNEYDFLLDTGATTAISENLYDLIKTNKLGSVKIKDQSGITDSLKVVSIPEIIINEIKFKEIPAFVSKRGINPIFECFKIDGIIGSNLLRNSTIQFNSQKNEIILTDNSKNLGLKKRDAIEMKVNQIQSSPFIPIKLIKEKHEGNGYVLFDSGDNDFYVISNTAYHQLQSQVDIFETIAKNVGTFSVGLFGTANENEHLALKVKKLKIGNMDFNNVITKTTYGETSRIGSELLKYGKVTLDYKKELFWLENFNEKKSIELAEKMWPIEPILNNLNEIVVGIIWDNSLKNKINLGDKILKFGYIDYENMDYCEIINLTSKINESKAKLIFQDKNTKEIKELELNKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAL1</accession>
    <name>A0A5C6ZAL1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19565</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000043">
        <property type="protein sequence ID" value="TXD86689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023036553" evidence="1">
        <location>
            <begin position="21"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="137" mass="15856" checksum="AC9A425178709D75" modified="2019-11-13" version="1">MKTILLFFSFFLIVSCNSNDDDNGTPQEQHEIMATWNLTRFERGFAQPYQYVDEITWEINPDNTINVNIVDGTEVSNEMPLNISGSYNFTMSDIENELLIDDIIYKFQLSNTGEYLLIEDEIGFDADGMLLLFEKIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAS7</accession>
    <name>A0A5C6ZAS7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SIR2 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19765</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000047">
        <property type="protein sequence ID" value="TXD86608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039444">
        <property type="entry name" value="SIR2-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13289">
        <property type="entry name" value="SIR2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SIR2_2" evidence="1">
        <location>
            <begin position="131"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="341" mass="38864" checksum="3FD0093298D78CDB" modified="2019-11-13" version="1">MEKEDIYKQLQTWTNNIPLIILGSGASVPFRLPSMWALGEHIKTTIKFADSNDQIQFEEFIVEFDKTGDLESTLTNLQLRPNVLAEIVNKTWQLVSTADLEAYEHFIKKDVDFPLANLLKYFLNTAGKKVSIITTNYDRLAEYASSLAKAIICNGYSQNLIGHFSNSIQSNNLASLKGYTGQVNIWKVHGSLDWFKSKDDVNIQLPNRQNIPEDYSPLIVTPGLSKYSETHNEPYRTIFTQADSEIEQANGFLCIGYGFNDIHVQPKLITQIKNKKPIIVITKELTSKTKQSIIDNKCHNYMLIEEANSKDTRIFSSKFGEVIIEDTCYWELGEYLKLIIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZB22</accession>
    <name>A0A5C6ZB22_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19875</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000051">
        <property type="protein sequence ID" value="TXD86567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="220" mass="25390" checksum="B0906D03EA1F9194" modified="2019-11-13" version="1">MDNPSKITEGGVEYSLGKFDGKSILYDFPKILIYLNAKGKLLFGEKFRIYDEDKDILLKLCSYFIKDKENCKNYGIDIDKGILLSGPVGCGKTSLMKLLRHIVPMQRPYEMIPCRNVTFGFNHLGFKTVEEYGNTKFYCFDDLGVEPAGRFYGKDLNVMGEVLLSRYELYLDTKHKVKTHATTNLNAEELEERYGNRVRSRMRELFNLIAFDTKAGDKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZB62</accession>
    <name>A0A5C6ZB62_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">MATE family efflux transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_20110</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000057">
        <property type="protein sequence ID" value="TXD86483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13136">
        <property type="entry name" value="MATE_DinF_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044644">
        <property type="entry name" value="DinF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006603">
        <property type="entry name" value="DinF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="160"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="196"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="236"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="269"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="316"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="351"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="384"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="410"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD86483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="444" mass="49300" checksum="39F1C3D1B5EC7816" modified="2019-11-13" version="1">MSADISFKNINRLAIPALIAGVAEPLISLTDTAIVGNVDLNATESLAAVGIVATFLSMLIWVFGQSRSAISSLVSQYLGANNLEAIKSLPAQAILVMTLLSILIIGATYPIAEHIFKLYNADNLILDYSVEYYKIRVFGFPFTLFTFAIFGTFRGLQNTFYPMIIALTGAGLNIVLDIILVYGIQDYIPAMHIKGAAYASVFAQFIMAILSVIFLLKKTDISLKVRLPLNPEISRFALMVLNLFVRTLALNVTLYFATRFATSYGKEYIAAYTIGINLWFLGAFIIDGYASAGNILSGKLLGSKSYTNLIKLSNRLIGYGLICGVVLALLGAVFYYPIGRIFTEEPKVLKQFYSVFWIILAMQPLCALAFIFDGMFKGMGKMRYLRNLLLIATGVVFLPLLFILDHYNLKLYAVFIAFTFWMVARGIPLIIKFRQLFLPHAENH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZB89</accession>
    <name>A0A5C6ZB89_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">S9 family peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000032">
        <property type="protein sequence ID" value="TXD87001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S9" evidence="1">
        <location>
            <begin position="702"/>
            <end position="873"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="886" mass="104151" checksum="43438807E6D4F34E" modified="2019-11-13" version="1">MMATKKHFLVKNFYLFLVFFLTMVCPMNGQTIKNKVVEESDYHLWGYLKQDQLSNYGKWASFHMSYESNKDTLFIKSIDTHKLFAIPNGYNSKFSLDENWVAFQSYDGYVGLLNLRNGKREHFEDATIYDWSNSGHYLSLYFQVEKKLIIRDIRSGFSKTFSGITDHHFNHKGNILAYIQEMDGMNKVVKINLENNFSEHPIYRSPDKIQNLKLHETKESLIFLEEYSHPDYIEKSHVIHFYNNKLNSYDPRLEKDFPKDKYVSRNLIISVSDFFISKQEHRIFFPIQKWTRVSDTFASRNEDQVEIWHYKDTEVFPRQENFNFSVIGAKLAAWDLKDNKIDEITNSSQGLYVLNESHTHALIYSDSEYLPLFKHQGLYSDVYIFDLEKHQKSLFLDKLNLENPILSSPKGRYFNYFRDNNWWIYDLDSQKHFAITKAIKEKITKDFSLTSRETIPLSFPVWSRDENEIFISGVNNIWRMNLINSTTAQLTNGFKHGYSYEIYNGPRASQNARAIHHNKVSIIENPKEIIVKKTSLQSKFSGFEILNENSQNETLVYGDILTDELFSSKNNKTMVFRQQRYDQSPQLKLYKDGELSDLYQSNTHEHKFYWGSSKLIQYKDSKNKPLQGILYYPSDYDSEKQYPLIVIPYDQQTRYYNQFILPSMAADGELLTSVLNLKGYFVLLPDINYEEGNAGISASNCIVSATKKAMELENINPNGIGIMGHSFGAYETYFTITQTNLFSAAIAGSGFSDLFTFSLSIHPGFRNHPETNYFEFGQIRMNKPFYEMKDLYLKNSPIFQSDKINTPLLSWSGKNDSRVFWNQSLYMYLALRRMEKENIMLIYPNEYHVLTKKENQLDLTSKVLDWFDYHLKGHEPKDWITNTNQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBG6</accession>
    <name>A0A5C6ZBG6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_20640</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000097">
        <property type="protein sequence ID" value="TXD86054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="209" mass="25125" checksum="0463E482C786D494" modified="2019-11-13" version="1">MRNILTSILILCFIGVKAQHWSDINEDLGITDTLNYPTEIRIYAGGGITNYTSLFRMYKSEPDNWTSEFYEHWSNVNGVMEMKTQKKLLSSKSEMEYVYLNLFRSYIFELPNRSEIDWKLAERGVIKKEEKRYSSKHKKTRTEWDILTNKSTDLDGTSYFFKAKNRYMSNEFEFGNPFYYRDKYPEIDEPKYVCELIEIIRSEFEIWEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC39</accession>
    <name>A0A5C6ZC39_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Shikimate kinase</fullName>
            <shortName evidence="2">SK</shortName>
            <ecNumber evidence="2">2.7.1.71</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">aroK</name>
        <name evidence="3" type="ORF">ESY86_18660</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + shikimate = 3-phosphoshikimate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13121"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.71"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="2">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 5/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the shikimate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.71" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000033">
        <property type="protein sequence ID" value="TXD86950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00088"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004765">
        <property type="term" value="F:shikimate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00464">
        <property type="entry name" value="SK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00109">
        <property type="entry name" value="Shikimate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031322">
        <property type="entry name" value="Shikimate/glucono_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000623">
        <property type="entry name" value="Shikimate_kinase/TSH1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01202">
        <property type="entry name" value="SKI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="1 2" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="10"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="172" mass="19403" checksum="9BE8C52F55DC689B" modified="2019-11-13" version="1">MTIALIGYMGSGKSQIGLELSKTLNYKFLDFDAYLEEKEQMPVKEIFKSKGELYFRKLETKYLAQVLQLENSIISLGGGTPCYGNNMDQIVNAIGVKSVYLKTSIPTLCARLFDERAKRPLIAHLNAEADLQEFIGKHLFERSIFYMKASHSIQTDGKTVEQLAQELAVKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC89</accession>
    <name>A0A5C6ZC89_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Lon protease</fullName>
            <ecNumber evidence="5 6">3.4.21.53</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">ATP-dependent protease La</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 13" type="primary">lon</name>
        <name evidence="13" type="ORF">ESY86_17180</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6 9">
            <text>Hydrolysis of proteins in presence of ATP.</text>
            <dbReference type="EC" id="3.4.21.53"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5 6">Homohexamer. Organized in a ring with a central cavity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="induction">
        <text evidence="5">By heat shock.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 6 9 10">Belongs to the peptidase S16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.53" evidence="5 6"/>
    <dbReference type="EMBL" id="VORO01000025">
        <property type="protein sequence ID" value="TXD87402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034605">
        <property type="term" value="P:cellular response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006515">
        <property type="term" value="P:protein quality control for misfolded or incompletely synthesized proteins"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01973">
        <property type="entry name" value="lon_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027543">
        <property type="entry name" value="Lon_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004815">
        <property type="entry name" value="Lon_bac/euk-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008269">
        <property type="entry name" value="Lon_proteolytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027065">
        <property type="entry name" value="Lon_Prtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003111">
        <property type="entry name" value="Lon_prtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046336">
        <property type="entry name" value="Lon_prtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008268">
        <property type="entry name" value="Peptidase_S16_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10046">
        <property type="entry name" value="PTHR10046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05362">
        <property type="entry name" value="Lon_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02190">
        <property type="entry name" value="LON_substr_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001174">
        <property type="entry name" value="Lon_proteas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00464">
        <property type="entry name" value="LON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00763">
        <property type="entry name" value="lon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51787">
        <property type="entry name" value="LON_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51786">
        <property type="entry name" value="LON_PROTEOLYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01046">
        <property type="entry name" value="LON_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword evidence="5 6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 5 6" id="KW-0645">Protease</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0720">Serine protease</keyword>
    <keyword evidence="4 5" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="Lon N-terminal" evidence="12">
        <location>
            <begin position="44"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="Lon proteolytic" evidence="11">
        <location>
            <begin position="627"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 7 9">
        <location>
            <position position="714"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 7 9">
        <location>
            <position position="757"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <begin position="391"/>
            <end position="398"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR001174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001174-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001174-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TXD87402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="817" mass="91958" checksum="426323F124E9100D" modified="2019-11-13" version="1">MAKSNFLSLDNLSFQEFDENSELIPLMTPEDEEEINKELLPDSLPILPLRNTVLFPGVVIPITAGRDKSIKLINDANNGIKTIGVVSQKDETIEDPEAKDIFKTGTVARILKVLKMPDGNTTVIIQGKKRFEIEEVISETPYITAKVKDVPEAKPALENEEFSAIIESIKDLALQIIKDSPNIPSEASFAIKNIESNSFLVNFVSSNMNLSVDEKQKLLEINDLKERALATLKFMNTEFKKLELKNDIQSKVQSDMNQQQREYFLHQQMKTIQEELGGGVSSGEEIEDMRVRAKKKKWDEKVSKHFDKELSKMQRMNPQVAEYSIQRNYLDLFLDLPWDEFSKDKFDLKRAMRILDRDHYGLDDVKKRIIEYLAVLKLRNDMKSPILCLYGPPGVGKTSLGKSVAEALGREYVRMSLGGLRDEAEIRGHRKTYIGAMPGRIIQNLKKAGTSNPVFVLDEIDKLSNSNQGDPSSALLEVLDPEQNSEFHDNFLEMGFDLSKVMFIATANTLNNIQPALMDRMEIINVTGYTIEEKVEIAKRHLLPKQLKEHGLTEKHLKIAKPQLEKIAEGYTRESGVRGLEKQIAKMVRHAAKNIAMEETYNLKVTNQDVLDVLGSPKLMRDKYENNAVAGVVTGLAWTQVGGDILFIESILSKGKGEMSITGNLGKVMKESATIAMEYIKSNAEEFGIDPDVFSKYNVHIHVPEGATPKDGPSAGVTMLTSLVSLFTQRKVKQHLAMTGEITLRGKVLPVGGIKEKILAAKRARIKIILLCEANRRDIEEIKPEYLKGLEFHYVTEMSEVLELALTKEKVDKAKNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCE7</accession>
    <name>A0A5C6ZCE7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Type II toxin-antitoxin system HigB family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_20390</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000070">
        <property type="protein sequence ID" value="TXD86312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_003436237.1">
        <property type="nucleotide sequence ID" value="NZ_VORO01000070.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110001">
        <property type="term" value="C:toxin-antitoxin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018669">
        <property type="entry name" value="Toxin_HigB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09907">
        <property type="entry name" value="HigB_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="98" mass="11732" checksum="1C230A6B5C5B7B00" modified="2019-11-13" version="1">MKRIIAKSTLREYWEIHADSEQYLKTWYDTAKSAKWFSPNDVKQTYINASILKDSRVVFNIKGNSYRLIVKFNYEKQWAFIRFIGTHAEYDKINADTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCK5</accession>
    <name>A0A5C6ZCK5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_15785</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="352" mass="39447" checksum="8F32EA260446799A" modified="2019-11-13" version="1">MPAPQFFPALSNLIGTENLPEPIKSAFDKVSDKLFYKTYYVEKSIYGDTAYHNLVLVLKGNAGINIFGGDDGLQLLFNPGTSANTIEIPIALYYRLPILKYLRRITLNELSTIEDYFNLILEMFGISKPELVFEAFDIFLDGYDDTVLAFVNQFNANSNYSEYQPLPLPQTGNQFSDITELISFFESFGLDINLYILETYIDGSDLSKGFENMSLLFDRFLGEFSIDTLIDLFIPRISVALQSLNLALAFPRNMLQPVDGQGNVIDDGSKSLLTYNVGSLLYDTKTGFDFINPDTFQLTRSQIGNSGFILEVTNLKLDLKDNTNIPEADAYGYGPEFKGIYAQSASITLPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCS9</accession>
    <name>A0A5C6ZCS9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amino_oxidase" evidence="1">
        <location>
            <begin position="9"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="Amino_oxidase" evidence="1">
        <location>
            <begin position="105"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="349" mass="39087" checksum="FC73C70A0DAC2691" modified="2019-11-13" version="1">MIIIIGAGLSGLLTAYRLKKEGIPFKILEARTRVGGRINTIYGTGHAPVEMGATWFGNHHKQLIALLDELEINYFEQYMEGRSFFQPYSNAAANAIQIPSQPPNYRIAGGTSKLINTLCQQFDEDELILNQSVKEIRCHKNAVQVIAKAVFEANTVILAIPPKLWANNILFEPQLPSDLMTVARQTHTWMEDSIKVALTYKQPFWQQENRSGAFFSNAGPVTELYDHCNHKRSKYALCGFINDSFKTLTYEKRRASVINQLKTVFGAQAEAFMDYEECIWSKEENTFEASITALYPHQNNGNPIFNEALYSGRLLISSSESASEFPGYMDGAVSSANMTAKKIITSNSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCT2</accession>
    <name>A0A5C6ZCT2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type II toxin-antitoxin system RelE/ParE family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18865</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000034">
        <property type="protein sequence ID" value="TXD86935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007712">
        <property type="entry name" value="RelE/ParE_toxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05016">
        <property type="entry name" value="ParE_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="80" mass="9326" checksum="076EFA77ACD7B576" modified="2019-11-13" version="1">MAHIAKKSPQNALHVLKTLTALADSLANMPYKYPMEPIYGSEQIRFVSKWAFKIIYRVETERIFILRVFSTNQDPSSFFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCV4</accession>
    <name>A0A5C6ZCV4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">SIMPL domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_20055</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000056">
        <property type="protein sequence ID" value="TXD86494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007497">
        <property type="entry name" value="DUF541"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04402">
        <property type="entry name" value="SIMPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="234" mass="27076" checksum="60D244DCA53B0ED4" modified="2019-11-13" version="1">MNRILLILGLILTCQISNGQTKNFIDQPYLETIAKVDTLIKPDIIYLDILIREKDERNRIPVEEMESKMIQKLKSLGINTEKQLTLSDLASNFKKYFLKQKDIMKDKAYELKVFDSQTAGKVLVALEEIGISNVNLDRTEYSKMEELKLELKAKAVEKARTQADFLVRPLNQKVTRAIHITDKYYETYNNFSGELQEVVVMGYSNKGKQEYEPPTIEFRPIKVESEVSIKFAIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD46</accession>
    <name>A0A5C6ZD46_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aldehyde dehydrogenase (NAD(+))</fullName>
            <ecNumber evidence="3">1.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_18185</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="1">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.3" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000030">
        <property type="protein sequence ID" value="TXD87062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004029">
        <property type="term" value="F:aldehyde dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043878">
        <property type="term" value="F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044638">
        <property type="entry name" value="ALDH7A1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43521">
        <property type="entry name" value="PTHR43521"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="6">
        <location>
            <begin position="36"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD87062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="517" mass="56019" checksum="AC9556E363F963BF" modified="2019-11-13" version="1">MEAVATDFGIKEALKQLGVKDINNGTSTGSNHFANGEVIESRSPVDAQLIAKVKTTSKEDYEKVMASATDAFKTWRTMPAPQRGEIVRQFGDKLREKKEPLGKLVSYEMGKSYQEGLGEVQEMIDICDFAVGLSRQLHGLTMHSERPGHRMYEQYHPMGVVGIISAFNFPVAVWAWNTALAWVCGDVCVWKPSEKTPLCGIACQNIAAEVFAKNDLPEGISCLINGDYQVGEFMTKDKRVALISATGSIKMGKTVAQEVAARLGKSLLELGGNNAIIVTPDADIKMTVIGAVFGAVGTAGQRCTSTRRIIIHESMYDKVKNAIVDAYKQLRIGNPLDENNHVGPLIDKDAVENYKHALKRVVEEGGKIIVEGGVLEGKGYESGCYVKPAIAEAQPDYEIVQHETFAPVLYLLKYSGDVHNALEIQNGVVQGLSSAIMTNNLREAEAFLSVQGSDCGIANVNIGTSGAEIGGAFGGEKETGGGRESGSDAWKVYMRRQTNTINYTTELPLAQGIKFDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD92</accession>
    <name>A0A5C6ZD92_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="195"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="233"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="259"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="298"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="317" mass="36331" checksum="36BFB67D3A3ABCC4" modified="2019-11-13" version="1">MELFLGYLGFIICAYAVIANDVIQTLGTFMASNHTLKWWWLWLFAVSILAATLVYGWYVHNGDVTYGRLTQIPLPETLEWWYLLAPITLLIITRYGIPVSTTFMILSVFSAGHIIEKMILKSVYGYALAFVFSILIYILISKKLESKFALEKLDKAARKHYWLIAQWISTGFLWSQWLIQDFANIFVFLPRKLDVLSLILSLAIIFVIMAYIFKKRGGKIQEIVNQKSNTKNIRSATIIDLIYGIFLFIFGNLDAVPMSTTWVFIGILAGRELAMSYLLNKEKMEPTYIIIAKDLAKVNLGLIISVVIAFSIQFFKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDD9</accession>
    <name>A0A5C6ZDD9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19240</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000038">
        <property type="protein sequence ID" value="TXD86790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="117" mass="13749" checksum="E45434AAE24AC980" modified="2019-11-13" version="1">MMVPAHFNELIEQAEELALYHKLIVQINKDFLLANIDLDFELDILPSSLKFMLHETVYKLIASKFADYLNLLYIIDVSEEKIRSLDGSDPVKLSEQVSFLILQREWQKVWLRNKHSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDI4</accession>
    <name>A0A5C6ZDI4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18085</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000029">
        <property type="protein sequence ID" value="TXD87136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022761767" evidence="1">
        <location>
            <begin position="21"/>
            <end position="436"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="436" mass="47816" checksum="1AD316D2CB84C166" modified="2019-11-13" version="1">MKKITQLSFLLLFAFVSVSAQQEKGIIGSSNWLRNWTEFSPNKTQYGEPTQILTGNISTDTKLNKKDVYLLLGNVFVTDSTQLTIEPGTVILGDYKTNGTLTISKGCKIIADGTETDPIIFTSNRNVKKEGDWGGLFILGDAPINKYGNGAAITYGMRPANPESITYGGQNVKANSGILNYVRIEFAGKRTKDFGFFDALTLAGVGSETQIENVMVSYCAGNSFNVIGGVTNLSKMVSFRSSSNDYKFNYGAQSNISNSLAIRSPYVSGVETARCMYVSSYDNKQDVDFSKKGTSVTARNLTLVNVSDNLASDIKVGLVKAALYISKDAAMDISKSVISGFNPAVVFDNAIVVNSENLDRLKFTEMYFNNCKGNIFIENNSNNEDLENWYGNRAFSNVYSKGDDAETFIDLQSTTSPDYRLRINKIIASNDLELDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDJ2</accession>
    <name>A0A5C6ZDJ2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19085</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000036">
        <property type="protein sequence ID" value="TXD86861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="548" mass="62568" checksum="58FD03F9E2830D71" modified="2019-11-13" version="1">MELIQNNPYRIAGILSNATERELQKQKTKIKAYSKVGKEINSDYDFQALNGITRTEDSIDKAFSTIEQNQDKVNYALFWFLNANPFDNTAIDYLKNGDKEKAIEIWEKVTQNKDVNSKNFSAFNNLGTYKLLSKTQDEIKEGIEAKIKLIESEYFENFVHSVADETYTIDNEKQIEKLVDELLTQFKNQYSSSETLQLFSNCNGSTQNYLSKKFTEEPLHNIESQISSSKNKRKDNKIDAYQFGLNLASNCKDDLVTLQSLLGITDLKYKTIADQLANEIMQCGIDYFNESLENDSSDNYLEQAQKLTKIADRIAVGKLTKDRAKDSLASLADMKDREINQAIAVLSSIKLAYDKAISEIDAQVSSMRMNMPYNQSINYSKVDKMKTSCLNWSKVVERVSSEISLSDIATIRNCSNQSKVSEYQNLVDFLFSKLGPIQINQVKHICYWKDVRAAQAKSTAKKVGSTISSATDKGCYIATMAYGDYDHPQVMKLRNFRDGCLSRTIVGRRFIKFYYKYSPSLVEKLKNKQNINLIIRKGLDQFIKAIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDJ7</accession>
    <name>A0A5C6ZDJ7_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L36</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpmJ</name>
        <name evidence="6" type="ORF">ESY86_14940</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the bacterial ribosomal protein bL36 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00251">
        <property type="entry name" value="Ribosomal_L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000473">
        <property type="entry name" value="Ribosomal_L36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035977">
        <property type="entry name" value="Ribosomal_L36_sp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00444">
        <property type="entry name" value="Ribosomal_L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57840">
        <property type="entry name" value="SSF57840"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01022">
        <property type="entry name" value="rpmJ_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00828">
        <property type="entry name" value="RIBOSOMAL_L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD87963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="38" mass="4573" checksum="49408FBAE436DD41" modified="2019-11-13" version="1">MKVRASVKKRSVDCKLVRRKGRLYVINKKNPRFKQRQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDV3</accession>
    <name>A0A5C6ZDV3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_14510</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="237" mass="27390" checksum="B5F41A3F1A17CD09" modified="2019-11-13" version="1">MGKMPKKTVAVLIILFFLPVVFLLFLYPAKHNYDPLQIVDNEVAELQFFNTGTQDQVKLEDQITILGFFGNNPLNYATAASNLKELVYDKFKGFKGFQIVILLPNGTEAQAKALHDEINNYEDMRFWYYTYGTPNDIQAVFNSLDNKLDLDSDLSSPEVFIIDKDLAQRGRLDDRTEREMEKNAPIVPLYSYDCIEVAEIKNKMNDDIRILFTEYRQKRKGDFDSSTRRGNNIKAKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDY2</accession>
    <name>A0A5C6ZDY2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">S9 family peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_14125</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023302">
        <property type="entry name" value="Pept_S9A_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002470">
        <property type="entry name" value="Peptidase_S9A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02897">
        <property type="entry name" value="Peptidase_S9_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00862">
        <property type="entry name" value="PROLIGOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S9_N" evidence="2">
        <location>
            <begin position="30"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S9" evidence="1">
        <location>
            <begin position="505"/>
            <end position="710"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="715" mass="81584" checksum="229A827E48499803" modified="2019-11-13" version="1">MPKFTLTILCFVIIGKAFAQKTYDYPVVLKDSTSDSYFGTVINDPYQWMENVNDERLTAWFDAQSKLVRKVKRKLPVMDLRTQITTMYNGVREDDIEGSPGDDKIEKSKYEFKYKYQNLNRSPNLLYRLRDQGNYKRLVDIKDFTTDKDENIEIVSRNVNEDEDLVAIKIARNGSDWCELYFFNLQNGEQFEHHLKYIRKGGDLVWDDKNMYYDRYEAAIEGRELLDMATGQKLFYHELGKPQSNDHLLYVNPDNTGTNGFTFGKFNDKLLFYKPYLHEQVVYRSVSIATVDDMAIDFKNAFIYPNERSLDLAVEALFGDKILIKTNWNAPNGRVLLADLNTPNQPVELVPEYDVMLKYLRRLGKDKFVCVYKNGNSELALIFDLEGKLLRKIEFPEGKKVNYLYENSKTATSTQFSVSSFYHPELWYQLSLEDLTFEPTIALSVPYDPEALETRFVNYTSKDGTEIPMYITCLKDVELNGENPTLLYGYGGYGITVEPSYNASKALWLLKGGILAVPNVRGGGAEGLDWGLQGRRLNKQNTIDDFIAAAEYLIEENYTNSSKLGANGGSHGALLVSAAAVQRPALFKAVVAEAGPYDMLRFGNYTVGAVNTNINEFGTVTNQEDYENLKSYSPLHHIMEDVKYPNMLLITGDGDDRVPPFHTYKFLATLQEKASAESLFLLYQIPGAGHGGALNANDWFDKLVYKYAFLYGQLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE56</accession>
    <name>A0A5C6ZE56_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011110">
        <property type="entry name" value="Reg_prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07494">
        <property type="entry name" value="Reg_prop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023090294" evidence="1">
        <location>
            <begin position="20"/>
            <end position="790"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="790" mass="86715" checksum="DC0CDCE65DF123C7" modified="2019-11-13" version="1">MIKKIAVTFLVLISIQVKAQDFSSLWEGYFSYSEIRAIASGDDKIYAAAENAIFSYDVLSNEIQTITTIEGLSGETISTLYYSEAFDLLLIGYETGLMEVYSQNDASILSVVDILEKQTISPSRKIINHFNEVDGLVYISTDYGISVYDLNLLQFGDTYFIGTGGAQININQTTVANGFIYAACGQNNGVRKAALSNPNLIDFQQWTSIASGSFGAIVTVQNQIYTQRLDNTILKIVSDNLSPLTTYLSSPLDVKSVEEYLLVTLNNQVFVYDSNFNLLANAVPNAQFDAKFTVASLNDDELFIGTKAFGVLKTSLAAPFDYVSIKPEGPSSNKGFKIEAGDNELWLSYGEYTISYNPGPFNSRGLSHLRDGVWRNIPFDSLLGARNLSDIAINPFKPSQVFVSSFQDGLLEINSEVPTILYNRTNSGLESLVLPNSPNFVSIRVSDLKFDRSGLLWTLTSLVDRPLKSYDPATGQWRGFDFTELIPSSVNNELGFGDLDVGNNGTVWVASYRNGVIGYDTNTSEINKVSSEEQNMPSPTVRAVALDNRGQLWIGTDFGLRVLFNTSGFVNDPNPRVSEIVILEDGIPTELLSEQFISDIKVDGSNNKWVGTLDSGVFYFSPDGQETIYQFTTDNSPLPSNAISDISIDGQSGRVYIATSRGLVSFSSGGTKPQETLEDAYVYPNPVRPEYDILGYDDLNNINNGIKISGLTESVNIKITDIEGNLVAEAQSQINKRSSRASYNFAIDGGTGIWNGKNLRGNIVATGVYLILISDLESFETKVLKVLIVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEC8</accession>
    <name>A0A5C6ZEC8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methyltransferase domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12785</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltranfer_dom" evidence="1">
        <location>
            <begin position="62"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="238" mass="27346" checksum="6659C12C4FC38468" modified="2019-11-13" version="1">MSVLVNTKQRSQEPEIMDDLDYNGPILHDALDKLAKINQWLGGNKVTVNALKKALKDHPKSEPITIIDLGCGGGDILREVSRFGKKQGFQFQLIGIDANAHTVAYASELSQDYDNLEFLAMDVFSEAFENLQYDLVLTTLFLHHFTEEELVHFLKPVLEKSKLGIVVNDLHRHKLAYYLFKLMCTAFNIKNRTIVEDGLTSVLRGFKRPELESISEKINANYEISWKWAFRFLWLLRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEG7</accession>
    <name>A0A5C6ZEG7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_16665</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000023">
        <property type="protein sequence ID" value="TXD87526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="286" mass="32376" checksum="C04E63AAD5B867A0" modified="2019-11-13" version="1">MHNSKIKLTAFFALAILAVSMMGFNKENTQIVKLSKFSLLAPVIVGQSHKITKETTDLELERIKSQFKAEGVDLKFPNTKRNALNEIFSISIEFKKTERTFFEKWNFNTKSNTPIKPFYLKLENDLLIHASETRIWNTYNLNAPPADAQSKPSFVVFNDQKKTDSKNTKTAMSSEETQSAKRSRSIAPFNPIDSSEVKTIALVITKDASDAFLEKQKIDLKTYGIEAKFSKIERNDAGEITSLKITLNDNQGRKSSSIWNEKEQAIPDIVMGKSKDDTLFISPVEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEH8</accession>
    <name>A0A5C6ZEH8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">50S ribosomal protein L17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rplQ</name>
        <name evidence="7" type="ORF">ESY86_14965</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit. Contacts protein L32.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the bacterial ribosomal protein bL17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1030.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01368">
        <property type="entry name" value="Ribosomal_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000456">
        <property type="entry name" value="Ribosomal_L17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036373">
        <property type="entry name" value="Ribosomal_L17_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14413">
        <property type="entry name" value="PTHR14413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01196">
        <property type="entry name" value="Ribosomal_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64263">
        <property type="entry name" value="SSF64263"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00059">
        <property type="entry name" value="L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01167">
        <property type="entry name" value="RIBOSOMAL_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="128"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="155"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD87968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="172" mass="19528" checksum="9EBF34D28605825F" modified="2019-11-13" version="1">MRHGKKFNHLGRQTAHRKSMLANMACSLIEHKRINTTVAKAKALKQFVEPMITKSKTDTTHSRRIVMSRLRQKDAVIELFRDVAVKVADRPGGYTRIIKLGNRLGDNADMAMIELVDYNEIYNVNKPDKKSTRRSRRGGTKTAETTTPVDTEASKETTASKEETKKTPKEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEM4</accession>
    <name>A0A5C6ZEM4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transporter substrate-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_14225</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell outer membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the transglycosylase Slt family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008933">
        <property type="term" value="F:lytic transglycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000270">
        <property type="term" value="P:peptidoglycan metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000189">
        <property type="entry name" value="Transglyc_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008258">
        <property type="entry name" value="Transglycosylase_SLT_dom_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01464">
        <property type="entry name" value="SLT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00922">
        <property type="entry name" value="TRANSGLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="domain" description="PBPb" evidence="7">
        <location>
            <begin position="54"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD88042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="481" mass="55783" checksum="96BD328E5C6E7D99" modified="2019-11-13" version="1">MKSFYLLFKTYYVLFFLGLFLMSCQQTQEEPTTTETPKIKRDLAAIKKDGTLKALTVYSGTSYFLYKGQAMGYEFEMLERFAEHLDLELEIIVVKDLDELMSKLNNGEGDILAHGLTITSNRKASVAFTNYLYLTKQVLVQKKPDNWRRMHWKKLENALVHDAIELLQDTVSIRKGSSYSERIANLSDELGGSIAVEYLSGELATDEIIKQVAEGNIKYTIADNNIAKIMASYYPILDVEVPVSFSQRIAWATRKNSPELLKATNQWLDSFKGKLDYNVIYNKYFNNTRDFRRRTKSEFYSLNNDEISPYDDLIQKHAERINWDWRLVASLIYQESRFDPNNSSWANAQGLMQLMPKTAEELGVVDRNDPKQSVRGGTTYLKKIWNDFENITDSIQRTKFTMASYNCGLYHVRDAQKLAIERGLDATVWDDNVEEMIVALSLPKNYNNPLIKYGYVRGMEPYNYVNQIFERYAHYTQFIAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZES8</accession>
    <name>A0A5C6ZES8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">MoxR family ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_15950</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000021">
        <property type="protein sequence ID" value="TXD87653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011703">
        <property type="entry name" value="ATPase_AAA-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041628">
        <property type="entry name" value="ChlI/MoxR_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07726">
        <property type="entry name" value="AAA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17863">
        <property type="entry name" value="AAA_lid_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_3" evidence="2">
        <location>
            <begin position="87"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="AAA_lid_2" evidence="3">
        <location>
            <begin position="284"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD87653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="363" mass="40704" checksum="E14B0BF0FF47B99E" modified="2019-11-13" version="1">MEHTNDPEHEDLRPNAAEEQLEETTSQTPEAPKPDTSEASDLSFENRIDLNELSKGVALIRNEISKVIVGQKSMIDMLIASILANGHSLIEGVPGVAKTVSAKLLAKSLDIGFSRIQFTPDLMPSDILGTSVFNMKTTEFEFKEGPIFSNMILIDEINRAPAKTQAALFEVMEERQITIDGSRYMLDLPFIVLATQNPIEQEGTYRLPEAQLDRFLFKIDVDYPNVDEEVEILNREQHLRGSSKTAQITAHLSKEQINHFQDLVTQIKVESHLIKYIADMIVNTRNNPFLYLGASPRASIAILKASKAFAAMDGRDFVTPEDIKRSAVPVLQHRVIVTPEREMEGVTTKQIIKQIIEAVEIPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF77</accession>
    <name>A0A5C6ZF77_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3 4">Single-stranded DNA-binding protein</fullName>
            <shortName evidence="2">SSB</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ssb</name>
        <name evidence="5" type="ORF">ESY86_15405</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04496">
        <property type="entry name" value="SSB_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00984">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000424">
        <property type="entry name" value="Primosome_PriB/ssb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011344">
        <property type="entry name" value="ssDNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10302">
        <property type="entry name" value="PTHR10302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00436">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002070">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00621">
        <property type="entry name" value="ssb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50935">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR002070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD87856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="111" mass="12392" checksum="4D0B95398BD9C051" modified="2019-11-13" version="1">MSTLRNKVQLIGNLGNDPEIVKLESGKTLAKFSIATNESYKNAKGELVKDTQWHNVVAWGKTAEVIEKYLTKGKEIAIEGKLTSRSYDDKEGVKRYITEVVCNEMLMLGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFE5</accession>
    <name>A0A5C6ZFE5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">FtsX-like permease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_13365</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="297"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="343"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="390"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="438"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="687"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="739"/>
            <end position="761"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="773"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="20"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="328"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="439"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="716"/>
            <end position="798"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD88338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="810" mass="90247" checksum="B3706D06FAE8E2C3" modified="2019-11-13" version="1">MFRNHIKIAFRSLKNQPFFTLINTFGLAIGMAGSLLIGLYIYDELSYDKMFADAGRIYRIDMDIKFGGAEIKSAETAPPMAAALQRDFAEVENTVRFRILGSNLFRSSDKSANIKELSTTYVDATFFDMFGLELIDGNKETALKEANTLVMTRTAAENHFGSINVVGKSLLLNNEDTYVVTGVMEDLPKNSFLKDYSIFMAMAGNVASRENIWGSNNYFTFVKVLPATRMDHFQLQLDGLLEKYILPWAQKTFPGMTAASFAASGNYIRYHTIPLTNIHLHSDNQIEMGEKGTIQNVYILSFIGFFLIFLACVNFMNLSTAHSLKRAKEVGIRKTLGSNRIQLIVQFLTESSLISFASMILAVIVAFIALPFFNDLAGRTISIPFTEPLFYVAILLFTMVLGLFSGSYPAFVISRFIPVETLKGNGFKNGSKWNIRSMLVVFQFGIAVFLIVGTLVIFQQLQFIQNKDLGYSKEQVLVISDSYAAGQQVNAFKHEVLSLSAVKSATLSSFMPIASARSNSSFFREDAMDQKFAIQMQTWDVDHDYMKTFGMELIAGRGFNNQSVADSTATIINESTLTTLGLSAQEALGKRITEDVELGKPVFYRIIGVIKDFHYESLREDIGALGLFLNKSTGSMAVKLQTDDFASAISSIENIWNEQAPGQPFNYRFMDDAFDTSYNEERRLGNIFIVFTSLSIFIACLGLFGLAAFNAQKRTKEIGVRKVLGASVSQITFGLTTDFLKLVAIATAIALPLGWFVMNIWLQDFSYRIQISWEILAFAAFLVILIAILTVSYQSIKAAIANPVKSLKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFI5</accession>
    <name>A0A5C6ZFI5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Threonylcarbamoyl-AMP synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15045</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006070">
        <property type="entry name" value="YrdC-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01300">
        <property type="entry name" value="Sua5_yciO_yrdC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="SSF55821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00057">
        <property type="entry name" value="TIGR00057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51163">
        <property type="entry name" value="YRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YrdC-like" evidence="1">
        <location>
            <begin position="14"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="206" mass="23097" checksum="AA0F7B4B38F31D20" modified="2019-11-13" version="1">MAELIRIYEENPNPKEIRKVVEVLRNGGLIIYPTDTVYGLGCDINNMKALEKVARIKGVKLEKSNFSFICHDLSNLSDYVKQIDTATFKILKRALPGPYTFILPGSKSLPNPFKKKKTVGIRVPNNKIALEIVKQLGNPIISTSIRDEDYVLEYTTDPELILEKWDKLVDLVIDGGYGDNEASTVIDLSEAEPKVVREGKGSLEIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFK3</accession>
    <name>A0A5C6ZFK3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_11535</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.220.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044946">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0680">Restriction system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="137" mass="14947" checksum="E64F12DAD7E5FA87" modified="2019-11-13" version="1">MHSQTNEQALESTIEKKLTGTTLETLKAEELSVDRVNESAVLYPAGNGYFIGQNSLIDYTVFISGVAQPKLPRGNLSAVKALAASQNDLNEISRYIETTSQKFSPAIGLKQEIEKLKEYKGSLINGVVTGKVRVCQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-02-10" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFN8</accession>
    <name>A0A5C6ZFN8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Isoaspartyl peptidase/L-asparaginase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_14275</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000246">
        <property type="entry name" value="Peptidase_T2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10188">
        <property type="entry name" value="PTHR10188"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01112">
        <property type="entry name" value="Asparaginase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="205"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="228"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <feature type="site" description="Cleavage; by autolysis" evidence="3">
        <location>
            <begin position="176"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR600246-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR600246-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600246-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="310" mass="33096" checksum="D72869F44209FCCF" modified="2019-11-13" version="1">MNTNFAIAIHGGAGTLIKGLMTPELENEYKLALEHARNEGYKVLEQGGTALDAVETAVKLLEDTPLFNAGKGAVFAAEGTHEMDAAIMDGKTRKAGAVSLVTGIKNPVALARDVMDNSYHVFLAGDGAMQFAKSNGYDILSPDYFYDEVRYQQWQGIKDTEGFQLDHSVKKDGKFGTVGAVACDQNGNIAAATSTGGMTNKKWGRIGDSPMIGVGNYANNKTCAISCTGSGEFFIRGVVAYDVACLMEHKNLSIQEASEEVIHKRILELGGDGGLIAIDAQGNIAMPFNTEGMYRASKTSKGVEMVAIYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFR5</accession>
    <name>A0A5C6ZFR5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="9"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="59" mass="7011" checksum="0EBFD11B86085CD4" modified="2019-11-13" version="1">MGREVEVEIEIEIELELEGEDEDEVEDEDEDEDEDEDEDDPDSYREKTIPIAIGRRRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG13</accession>
    <name>A0A5C6ZG13_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Glutamine--fructose-6-phosphate aminotransferase [isomerizing]</fullName>
            <ecNumber evidence="2 8">2.6.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">D-fructose-6-phosphate amidotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">GFAT</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Glucosamine-6-phosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Hexosephosphate aminotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">L-glutamine--D-fructose-6-phosphate amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 11" type="primary">glmS</name>
        <name evidence="11" type="ORF">ESY86_13720</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:13237"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58725"/>
            <dbReference type="ChEBI" id="CHEBI:61527"/>
            <dbReference type="EC" id="2.6.1.16"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.16" evidence="2 8"/>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004360">
        <property type="term" value="F:glutamine-fructose-6-phosphate transaminase (isomerizing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901137">
        <property type="term" value="P:carbohydrate derivative biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05008">
        <property type="entry name" value="SIS_GlmS_GlmD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05009">
        <property type="entry name" value="SIS_GlmS_GlmD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00164">
        <property type="entry name" value="GlmS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035466">
        <property type="entry name" value="GlmS/AgaS_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035490">
        <property type="entry name" value="GlmS/FrlB_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005855">
        <property type="entry name" value="GlmS_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10937:SF0">
        <property type="entry name" value="PTHR10937:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01135">
        <property type="entry name" value="glmS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8 11" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 8 11" id="KW-0808">Transferase</keyword>
    <feature type="initiator methionine" description="Removed" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="9">
        <location>
            <begin position="2"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="10">
        <location>
            <begin position="292"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="10">
        <location>
            <begin position="464"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; for GATase activity" evidence="8">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="active site" description="For Fru-6P isomerization activity" evidence="8">
        <location>
            <position position="610"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD88153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="615" mass="67883" checksum="791F011A25A98D82" modified="2019-11-13" version="1">MCGIVGYIGHREAYPIILKGLKRLEYRGYDSAGIALYDGDDIVLCKTKGKVADLEHKIESEISTKGNLGIGHTRWATHGVPNDVNSHPHYSNSGNLVIIHNGIIENYDSLRKELIKRGYTFKSETDTEVLVNLIEDVQKNDNLKLGKAVQIALNQVVGAYAIAVFDKNKPNEIVVAKLGSPLAIGVGDDEYFIASDASPFIEYTKSAIYLEDEEMAVIRRHKGVKIRKIKDDTLVDPYIQELQLNLEQIEKGGYDHFMLKEIHEQPSAIFDTFRGRLLSDKGIIKMSGVEDNMKRFLNADRIIIVACGTSWHAGLVAEYIFEDLARIPVEVEYASEFRYRNPVIYEKDVVIAISQSGETADTLAAIKLAKSKGAFVFGVCNVVGSTIARETDAGAYTHAGPEIGVASTKAFTTQITVLTLIALRLARAKGTISSSDYRLQLLELELIPDKVKKALESDDLVKSIAAIYKDAPNMLYLGRGFNFPVALEGALKLKEISYIHAEGYPAAEMKHGPIALIDENMPIIVIATKKGHYEKVVSNIQEIKSRKGKIIGIVTEGDEQVRALADHVIEVPESLESLSPLLTTIPLQLLSYHIALMLGRNVDQPRNLAKAVTVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG63</accession>
    <name>A0A5C6ZG63_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Polysaccharide export protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_09900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015159">
        <property type="term" value="F:polysaccharide transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003715">
        <property type="entry name" value="Poly_export"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019554">
        <property type="entry name" value="Soluble_ligand-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02563">
        <property type="entry name" value="Poly_export"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10531">
        <property type="entry name" value="SLBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="232"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="SLBB" evidence="3">
        <location>
            <begin position="141"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="255" mass="27694" checksum="0A7A2ACD72D46798" modified="2019-11-13" version="1">MKFNVLVIMLLVGTLLSSCASKKEILYLQDASKFDNSELSYGTTKIQPNDILRITVGALIEETAIPFNRSAGGQGGGGGIELIQLEGYLVTNENSISFPQLGSISTKDKTVLELEEYIKQMLESKGLLKAPTVNVRLLNAKVTILGEINSPGVYTFTEQNITLLQAIGYAGDLTINGKREDIKIIRELDGNRQIGTVDLTSGDFLNSDFYHVKPNDVIVVNPNDPRVKSAGFIGNVGTLLSVVSILFTTIVLITR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG99</accession>
    <name>A0A5C6ZG99_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptide chain release factor 2</fullName>
            <shortName evidence="4">RF-2</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">prfB</name>
        <name evidence="6" type="ORF">ESY86_11920</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="4">Methylated by PrmC. Methylation increases the termination efficiency of RF2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the prokaryotic/mitochondrial release factor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016149">
        <property type="term" value="F:translation release factor activity, codon specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00094">
        <property type="entry name" value="Rel_fac_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005139">
        <property type="entry name" value="PCRF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045853">
        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004374">
        <property type="entry name" value="PrfB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03462">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00937">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75620">
        <property type="entry name" value="SSF75620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00020">
        <property type="entry name" value="prfB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00745">
        <property type="entry name" value="RF_PROK_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0488">Methylation</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RF_PROK_I" evidence="5">
        <location>
            <begin position="239"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="modified residue" description="N5-methylglutamine" evidence="4">
        <location>
            <position position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD88667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="369" mass="42166" checksum="9794F971F5B2AB94" modified="2019-11-13" version="1">MITSDQIKDLQTRLDKLRHYLDIDAKLIEISNEEEQTFDPNFWNDSKKAEVIMKSIREKKNWVKDYNLAQTFVEDLEVIYEFYKEDEASAEDVQNRFEKALNSIEKLEFKNMLSEEGDSLSAVLQITAGAGGTESCDWASILMRMYLMYAEKSGFKVKELNFQTGDVAGIKTVTLEIEGDFAFGWLKGENGVHRLVRISPFDSNAKRHTSFASVYVYPLVDDTIEIEINPADIEITTARSSGAGGQNVNKVETKVQLTHKPTGIQISCSETRSQHDNRSRAMQMLKSQLYEIELQKQLAQREDIEAGKMKIEWGSQIRNYVLHPYKLIKDVRSSHETGNVDAVLDGDIEPFLKAYLMMMGQKEEDSNQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGH9</accession>
    <name>A0A5C6ZGH9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_09145</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="5"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD89213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="243" mass="27659" checksum="E8526D7411F43C18" modified="2019-11-13" version="1">MTHILNIKDLYKNFGKETILKNINLSLEKNTVLSLLGSSGSGKTTLLKIIAGLESEDKGELLLNGKNLANKKPQQRNIVYLYQEALLFPHLNAFENIAFGLRLKKVDSKVIMEKVNHMLEHLDMARHAEKMPNQLSGGQRQRISFGRAMVIEPELLLLDEPFGALDAITRGKMQELFKDLAHKMHISALFVTHDLKEAIVMGDQIGKIQKGQLLQYATKKEFYKDEFSGVQKEIDFWKQINNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGT8</accession>
    <name>A0A5C6ZGT8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_10740</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13174">
        <property type="entry name" value="TPR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="281" mass="32738" checksum="41A4A8A7FDFA03A4" modified="2019-11-13" version="1">MSLKQTLIFVAFLSVLLSCNNKKTPVDFTQLEDEEKADLAERYHQMSNYFLQPSELYRAYKDSALLVQPENVDYRQRLSYSYKKVGEHIKAMEVLNTAVSIDTANGKADALEYRAWTLLYYYRDYEGVVRDVDLIEKITGNAYNACWGEPCGFHKGQALYKLGDFDAAIANFERVNTEEEKLGFDSRDNYMIFFYIGRCYAEMQAYDTAIIYYNKALASVEQFPEAYYQLGLIYKSRNEPTIAKTNFELAKKHIGYGMNEAYVERLDEVFLHQIERELLEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH08</accession>
    <name>A0A5C6ZH08_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">General secretion pathway protein GspD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_09440</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial secretin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001775">
        <property type="entry name" value="GspD/PilQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004846">
        <property type="entry name" value="T2SS/T3SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00263">
        <property type="entry name" value="Secretin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00811">
        <property type="entry name" value="BCTERIALGSPD"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022818264" evidence="3">
        <location>
            <begin position="19"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="378"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="411"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="380"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="732" mass="81271" checksum="3AFBA3362969D6C1" modified="2019-11-13" version="1">MKNILYLLFLLSFSLLFGQTGQFPNEQQRIETIKNQLTILSTETLGLTENVKTEISVNNISLANFLLALSDIHKVNINVAPELSQVTIANNFSNVTVADLLIFLCKEYDLTIDFTGNILSIKKYEPTPPKIEQRIIPIAYDPSNNTISLDAKEDKLYDVFKKIMDESAKNIVFSPGLENRLITVYINDTPFETAMDNLAFANNLYMEKSKDGFFVFEDNTPTAISSTNNPNTELTSQRPTRRRNSNFFFKIKVPEQQLLEVDFVNTPIADIINDIGNELNIDIFTATPLDEAGTATFTAKSITFDELLSHLFEVQSQTISNTNTQSNENLNNLNQANFSKRFTFKKENNIYFFGTENQLSVRKVAIIHLQHRSVELLSDPAGGGSSSRSAGRNFNSNNNFNNFNGISNTPIGSYSQNRNREPVNTNSNQNFNNFSNKVEALINILPNEIKQDLDITVDYELNSFYVTGPSTNVERFKDFINRIDKPVPVILIEVMLIEVNNTTLVEAGVSWGIGAGPTTTQGGIFPETNLTLGAKTINKVIGGFDGFGSFNLGKVVPNFFATIKAMESNGNLKIRSTPKLSTLNGHRATFSNGQTSYYAVTQQAIIGSDNPVTQTAVNYVPIDAELGLTIKPLVSGDGQVTLDIFVVQSTFGARISQDAPPDISSREFSSIIRVKDQDIVVLGGLEEQMKNNSGSGVPFLARIPIIKWLFSKRKREAKKAKLTVLIKPTIIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH24</accession>
    <name>A0A5C6ZH24_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_10960</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD89001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="67" mass="7786" checksum="FF6CCD3FB61FEE5B" modified="2019-11-13" version="1">MDSQNKLINNIRLTTLEIHKEYPELVNDMTEVSKTFLSDTKNGTNNKELKAYLDSLNGIIKTYKEEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH44</accession>
    <name>A0A5C6ZH44_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DUF423 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_13935</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0382 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006696">
        <property type="entry name" value="DUF423"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43461">
        <property type="entry name" value="PTHR43461"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04241">
        <property type="entry name" value="DUF423"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="101"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD88195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="131" mass="14073" checksum="E365C76B2F8500E4" modified="2019-11-13" version="1">MNKICLLIAAFLGIVAIALGAFGAHGLKELIPVASQLTFETGVRYQMYHAIFLLFIGSFGALSSKSQRSICILVTLGVLLFSGSIYALATNNLSSFDFKAIGFITPIGGLLLIVAWVILFVNILKMKTDKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHD9</accession>
    <name>A0A5C6ZHD9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sigma-70 family RNA polymerase sigma factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_11135</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="6">
        <location>
            <begin position="21"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4" evidence="7">
        <location>
            <begin position="127"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD88785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="176" mass="20678" checksum="638FFF997789F0E5" modified="2019-11-13" version="1">MQLDTLVLNFQNKDEKAFEELYNMYSESMHGVIYNIVRDNDIAEEVMQDIFVKAWQKSNSYDASKGRFFTWILNIARNAAIDKVRSKDFKNAKKNLNSDFFVDILETSESLNDQTDAIGIKKYVDILQEKCKKIIEFLYFKGYTQKETSEELDIPLGTIKTRNRNCINELRKMLVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHF3</accession>
    <name>A0A5C6ZHF3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Universal stress protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_13530</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal stress protein A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="2">
        <location>
            <begin position="5"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="258" mass="29329" checksum="9990AFAA9D3E8849" modified="2019-11-13" version="1">MKKISTILIPFDFSKISEDALEYAVKYVGNDENLKIMLGHISNDRHMDELKARFETVEKRHHDVLKNKIEWVSMRGELTEALIQIQKSEQIDLIIMGTSGGTSLEPTNTSKLVLEADCPVLVVPSNLGEFRLKKIALVLGKEEIDDTEVLRTLLNVSQKFNAKVHVITIENRPETFGYSETDENNENKIQYFLENFYSEHVFIENPDVVDGILSYATQRDIDVITILPRNHTKKGQPSEGQLTELLTLHSPIPILAID</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHM3</accession>
    <name>A0A5C6ZHM3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="10">HlyC/CorC family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ESY86_07530</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04590">
        <property type="entry name" value="CBS_pair_CorC_HlyC_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002550">
        <property type="entry name" value="CNNM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044751">
        <property type="entry name" value="Ion_transp-like_CBS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01595">
        <property type="entry name" value="DUF21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0129">CBS domain</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="100"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="136"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="9">
        <location>
            <begin position="282"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="364"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="370"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD89628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="384" mass="42960" checksum="5B301CE84737E784" modified="2019-11-13" version="1">MSLLLLYAIISIFVSFLCSILEAVLLSITPTFIKLKKQEGKQYAEQLQVLKNDVDRPLIAILTLNTIAHTVGAILVGVQAKVAYAELYGSEQSSLFGINFTVDIMVGVVSTIMTILILVASEIIPKTIGATYWKNLANFTTTALRVMIFPLKYTGILWLLQLTTKLIGGKGHGSILSREGFLVMTDMAHEEGVFQANESKIIKNLLNFKEVFARDVMTPRTVMKAEDENTTVQDFFNKNINLRFSRIPIYAGDADNIRGLVLKDEVFKEMALDNGDKKLSEIKRHIIVIDREMPIPLLFDQLVETRNHMALVVDEYGSVSGLVTMEDVIETLLGMEIMDESDNVSDLQSMARKSWEVRAKKLGIVGNTPSEEHTEKDAEDHKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHP3</accession>
    <name>A0A5C6ZHP3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_07890</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="303" mass="34475" checksum="BA58AA59943CE48F" modified="2019-11-13" version="1">MEFKVGDSRRYGIFPDSLNNRLNPKTNKPLLTSLLDCAEKNQFEIEFIEGFYDLNLILDSRKNLSFKFNNSEFKLAHITNEKGARSEHINFKGKLILSDSFGSYYSDHITVDSLIIKTSTRKSLEGRKSRGCHIYKGTNNLHINYLKIQNLASGSEVYENNHAALAIDGLRENPTYITIDEAIIESSDRHGVYITGSQNSIKKLKINSYGQGTTVYMSGMQDSDRGEERVLSGLWINRCNDCQFDEVEIHTKNSKGFPLKLDEGDASRPTFIKLLKMDVPYKDELILDDILTNVLVKKIELVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHW8</accession>
    <name>A0A5C6ZHW8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DEAD/DEAH box helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_10895</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD89014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="1">
        <location>
            <begin position="32"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="2">
        <location>
            <begin position="233"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="517" mass="59257" checksum="DA5035E03B413802" modified="2019-11-13" version="1">MTDKDLGLQDKKTDKELYSYQKGAIDQIFDKFETAADDYHLLYQLPTGGGKTVIFSEIVRQYLKTHKKKVLVMTHRIELCKQTSKMLTSFGVSNKTIDSKANLDDQEDYSCYVAMVETLNNRLNEEKLDISDVGLVIIDEAHYNSFTKLFKFFENAFLLGVTATPLSSNKDLPMKGNYNELIAGESIGALIENEFLARADVYQYDMGLTSLEVGSNGDYTVKSSEDLYSSPAMLDKLLEAYRKHSDGKKTLIFNNGINTSIMVYHTFKEAGLPVMHLDNTATKKQRKQILNWFKETPNAILSSVSILTTGFDEPTIDTIILNRATKSLTLYYQMIGRGSRILNNKSKFTVIDLGNNNYRFGPWGADLDWNTIFSSPDYYMDKLMDDEAIEGQFRHELPEEIRKEFSKSEEVYFDIEQVYKDATFGGESSKVVLERSIEQHAKICIENSEDVYDALALAKLLEDDIDNRIDVYAKCISKSTYNFLKWLRDDYKQKLKSYLRSNFDEVFEQIHGHPPEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHX0</accession>
    <name>A0A5C6ZHX0_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Diaminopimelate epimerase</fullName>
            <shortName evidence="8">DAP epimerase</shortName>
            <ecNumber evidence="4 8">5.1.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">PLP-independent amino acid racemase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">dapF</name>
        <name evidence="10" type="ORF">ESY86_11050</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>(2S,6S)-2,6-diaminoheptanedioate = meso-2,6-diaminoheptanedioate</text>
            <dbReference type="Rhea" id="RHEA:15393"/>
            <dbReference type="ChEBI" id="CHEBI:57609"/>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
            <dbReference type="EC" id="5.1.1.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; DL-2,6-diaminopimelate from LL-2,6-diaminopimelate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the diaminopimelate epimerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.1.7" evidence="4 8"/>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008837">
        <property type="term" value="F:diaminopimelate epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00197">
        <property type="entry name" value="DAP_epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018510">
        <property type="entry name" value="DAP_epimerase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001653">
        <property type="entry name" value="DAP_epimerase_DapF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31689">
        <property type="entry name" value="PTHR31689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01678">
        <property type="entry name" value="DAP_epimerase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00652">
        <property type="entry name" value="DapF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01326">
        <property type="entry name" value="DAP_EPIMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 8" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="75"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="188"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="199"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="198"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="170"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Could be important to modulate the pK values of the two catalytic cysteine residues" evidence="8">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <feature type="site" description="Could be important to modulate the pK values of the two catalytic cysteine residues" evidence="8">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD88771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="259" mass="28513" checksum="E254F249BB819328" modified="2019-11-13" version="1">MILEFYKYQGTGNDFVMIDNRQKIIANYESQKISHLCDRRFGIGADGLILLESHDTMDFKMVYFNADGNQSSMCGNGGRCIVAFARFLGLIETQATFEAIDGAHSANIEGDKVSLQMQDVKGIETHKTHTFLDTGSPHHVELVSDLNRLDVKSRGASIRYGAPYNEAGTNVDFVTKNAADSFSVRTYERGVEDETYSCGTGVTAVALAMNYTGETDKNRIKLLTPGGALEVSFEKTETGYQDIWLIGAATQVFKGAIVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI34</accession>
    <name>A0A5C6ZI34_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF1684 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012467">
        <property type="entry name" value="DUF1684"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41913">
        <property type="entry name" value="PTHR41913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07920">
        <property type="entry name" value="DUF1684"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022772229" evidence="1">
        <location>
            <begin position="18"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="199" mass="22963" checksum="B4D0992074FA91FA" modified="2019-11-13" version="1">MKYLVLVLIAFANLSCAQDKKPLAGDTQFQRELNAEFKDASKSPLKKRDLKNFEGLDFFKFDAAYVVEARVELKPNSEWFKMQTTTSRLSNKRIFAEFHFKLKGKNYMLNVYQDQDLMQEEGFEDYLLLPFIDDTNGLTSYGGGRYIDLTIPEGNTVSLDFNTAYNPYCAYNEKYSCPIVPRNNYLDLELKAGVKAFVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIF4</accession>
    <name>A0A5C6ZIF4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">PAS domain S-box protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_07010</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="4">
        <location>
            <begin position="4"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="4">
        <location>
            <begin position="135"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="5">
        <location>
            <begin position="203"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="5">
        <location>
            <begin position="327"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="408"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="374"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD89941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="625" mass="71003" checksum="6798228383789D3E" modified="2019-11-13" version="1">MIQTKEDFLQVLSSAISEGVVVVDELQIVVSTNTAADAMFGYATGELVGKPLSTLIPTRYHEKHDAYFESFYKNSETRSMGHGRELYGLHKNNTQFPVEVGLNPFEIYGKAYVMALVIDITERRHIERDLILKSEAIQATGNGIVISDALQKDQPIIFCNPAFKALTGYSSEEILGRNCRFLQANDRAQDGIDKLRDAIHAGKSYQTVLRNYKKDGTLFWNDLYVNPIKNSEGVVTHYIGIQNDITKRKNAEEERSYLTKIFDNSLNEIYVFDFYTLKFLNVNYGAQKNLGYTLEELKALSAVDLKPDYSENDFIKLTAPLVNKSESKIEFEAFHERKDGTRYPVFVNLELSKLGDRKVYVAIILDMTEQKNYTQKLERTVAKRTEELNSALEKEKELNELKTKFLSLVSHEFKTPLSGILTSSVLLGKYKLEDQQDKRDKHIRTITDKVHYLNSIVNDFLSIEKLETGQVNYKFTTFRLSKVVNEIVYNANMLLKEGQQIIYPEHIDDIFLTQDEKTIELALSNLVHNAIKYSSENTDVTISITQDDAVTTFKISDSGIGIPAKDLKNIFNRYFRAENVLTTQGTGIGLHIAKSHIEYVGGTIHCKSKENVGSTFIMTIPNKAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZII5</accession>
    <name>A0A5C6ZII5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Tryptophan-rich sensory protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="206"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="267" mass="29588" checksum="9907E05C679F89DC" modified="2019-11-13" version="1">MKKVLQIANGIALVSTIFINYLSNTGAINGTTIGQVSNDMKSLFTPAGYAFAIWGFIYLLLIGFIVYQGRSLFVKVRDDDFVLRIGWTFVISCVANSAWVFCFLYGYTGLSCVFIFLLLLSLLKIVIDNSMELWDAPMSVIAFLWWPFVFYSGWVTVASIANVSAYLVKTGWDGFGISAVTWTLIMIGVALIVNLAITWKRNMREFALVGAWALVAIAYANYEKHDVIVYSAALAAAILVISSGIHGAKNKDTNPFNKCKEYLQNKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIN9</accession>
    <name>A0A5C6ZIN9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Magnesium chelatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11335</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="1">
        <location>
            <begin position="165"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="486" mass="55413" checksum="A929EC325189DD17" modified="2019-11-13" version="1">MTEITTLGELKKSKYQSKSIKDELRDNLIQKIRNKETTFEGVHGYENTVIPELERAILSRHNINLLGLRGQAKTRLARLMLNLLDEHIPLVEGSEINDDPFNPISRYAKELIAEKGDDTPITWLHRSERFAEKLATPDVTVADLIGDVDPIKAANLKLSYADDRVIHYGMIPRANRCIFVINELPDLQARIQVALFNILQEGDIQIRGFKLRLPLDVQFIFTANPEDYTNRGSIVTPLKDRIGSQILTHYPTDIETARLITEQEAKLVESQKENVMVPDLARDLLEQIVFEARESEFIDSKSGVSARLSITALENLLSTAERRALRSGDEKTTLRMSDFVGIIPSITGKVELVYEGEQEGAAMVAYNLIGEAVKSLFPEFFPAIEKLKKQQEETPYDPIVSWFFNQKDGFELLDDVRDKEYKNLLDAISPLNDLLAEHQSKLKKEDSYFVKEFVLWALVEFKQLSKFRFTEGIQFQDPYGSYISGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJB8</accession>
    <name>A0A5C6ZJB8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidase T</fullName>
            <ecNumber evidence="5">3.4.11.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Aminotripeptidase</fullName>
            <shortName evidence="5">Tripeptidase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Tripeptide aminopeptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">pepT</name>
        <name evidence="9" type="ORF">ESY86_06650</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Cleaves the N-terminal amino acid of tripeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>Release of the N-terminal residue from a tripeptide.</text>
            <dbReference type="EC" id="3.4.11.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5 7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5 7">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase M20B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.4" evidence="5"/>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045148">
        <property type="term" value="F:tripeptide aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043171">
        <property type="term" value="P:peptide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00550">
        <property type="entry name" value="Aminopeptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010161">
        <property type="entry name" value="Peptidase_M20B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42994:SF1">
        <property type="entry name" value="PTHR42994:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037215">
        <property type="entry name" value="Peptidase_M20B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01882">
        <property type="entry name" value="peptidase-T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00758">
        <property type="entry name" value="ARGE_DAPE_CPG2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00759">
        <property type="entry name" value="ARGE_DAPE_CPG2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 5" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="M20_dimer" evidence="8">
        <location>
            <begin position="210"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="83"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5 6">
        <location>
            <position position="178"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="144"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="201"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="383"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR037215-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR037215-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD89876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="413" mass="46401" checksum="EDA5A91DF5E124C4" modified="2019-11-13" version="1">MISKEHIIKRFISYVTVDTESDPESTSTPSTANQWDLANALAKELISIGMKDVTIDTNAYIMATLPSNVEHEVPTIGFVSHFDTSPDFTGANVKPRVIENYDGKDITLNAEQNVILSPDYFEDLLLYKGQTLIVTDGTTLLGADDKAGITEIVSAMEYLIQNPDIKHGKIRVGFTPDEEIGRGAHKFDVDKFGAAYAYTMDGSQIGELEYENFNAAGAKVTIKGKIVHPGYAKGKMVNSMYIATDFINALPRMETPEHTEDYQGFFHLQDMDGSVDETVLKYIIRDHDKDHFEARKEVMQKLTEDFNAKYEREVVGIEIKDQYFNMREKIEPVMHIVDIAEEAMKQLHIKPLIKPIRGGTDGSQLSYMGLPCPNIFAGGHNFHGRYEYVPVESMIRATEVICKIAELTAEKHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJB9</accession>
    <name>A0A5C6ZJB9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA (guanosine(18)-2'-O)-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.34</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">tRNA [Gm18] methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">trmH</name>
        <name evidence="4" type="ORF">ESY86_10295</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>guanosine(18) in tRNA + S-adenosyl-L-methionine = 2'-O-methylguanosine(18) in tRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:20077"/>
            <dbReference type="Rhea" id="RHEA-COMP:10190"/>
            <dbReference type="Rhea" id="RHEA-COMP:10192"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74445"/>
            <dbReference type="EC" id="2.1.1.34"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.34" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009020">
        <property type="term" value="F:tRNA (guanosine-2'-O-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052665">
        <property type="term" value="F:tRNA (uracil-2'-O-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002938">
        <property type="term" value="P:tRNA guanine ribose methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd18092">
        <property type="entry name" value="SpoU-like_TrmH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02060">
        <property type="entry name" value="tRNA_methyltr_TrmH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033671">
        <property type="entry name" value="TrmH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43453">
        <property type="entry name" value="PTHR43453"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="1 2" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="SpoU_methylase" evidence="3">
        <location>
            <begin position="34"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="217" mass="24967" checksum="A3EFFCCA62BF98B8" modified="2019-11-13" version="1">MIDIALLEHLEGFLTTSRIERFKRIIAQRTRHFCVATEDVFQLHNTSAVMRSCDVFGVQDVHIVEEQNAKQIDSEIAMGSQKWVDVYRYQSVKDSLNHLKGEGYQIVATTPHENDSNLQDFDVSKKSCFFFGRETEGLSKEVIAEADAFLKIPMYGFTESLNISVSAAVILQHLTARLRESDVKWQLTEAQQLEKRLDWCRKTIKSNEAIEARFYKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJE9</accession>
    <name>A0A5C6ZJE9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_09465</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022849418" evidence="1">
        <location>
            <begin position="24"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="206" mass="24009" checksum="30DE6348FF38EDA9" modified="2019-11-13" version="1">MVNKAFFLIMVIAILAMHCGCQSSIYDNEESLLNYLKVESNGYVQHKTVNGVDFTLMYRPTDLLVKQEMGGMESTESIESLRKRYDKFLYFNLSMSRNNSELLNTEPKNKNQFTAMVNQLVFGMEEKVYLYTQKKDTIALADYIYPRMYGMTNATTIMFIYPKSEELLKQEYLTFVIQDLGLYTGEVKFKTELDLIINQPKLSFKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJH9</accession>
    <name>A0A5C6ZJH9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_04990</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="3"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="35"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="300" mass="33793" checksum="711187572B931B44" modified="2019-11-13" version="1">MSISISHISKSYKKVSALKDISFEVEAGELFGLIGPDGAGKTTLFRILTTLLIANEGAATVAGFDVVADYKNIRKSVGYMPGKFSLYQDLTVAENLNFFATIFGTTVEENYDLIKDIYVQIEPFKDRRAGKLSGGMKQKLALCCALIHKPKVLFLDEPTTGVDPVSRKEFWEMLKRLQLKGITILVSTPYMDEAALCDRIALIQDGKILEIDTPEAIVRHYPKAIYNVKANNMYQLIKSLNDYEHNHSVYPFGEYVHYTDSRTDFNPKELFQYLESNNLSAIEIEPTVATIEDTFMELAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJJ5</accession>
    <name>A0A5C6ZJJ5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="80" mass="9145" checksum="769814013185E35B" modified="2019-11-13" version="1">MITKRKSKPQMSFSKSKILPIVGLGILLFFIGISYFNNHVFLDKLIICSLILSMVYFARTLGKSNENEPNSDRKNYTDPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJL5</accession>
    <name>A0A5C6ZJL5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cation transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="SSF55008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMA" evidence="1">
        <location>
            <begin position="2"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="74" mass="8570" checksum="8CC2C14BF0D8361E" modified="2019-11-13" version="1">MRSTVHIQNLICDTCTKSIVKRLIELRHISDVAVDLKKETVSFDFFTKHDFEHAKHVLEMMGYTILGHDNILDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJL8</accession>
    <name>A0A5C6ZJL8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">GatB/YqeY domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_09415</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016884">
        <property type="term" value="F:carbon-nitrogen ligase activity, with glutamine as amido-N-donor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1510.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003789">
        <property type="entry name" value="Asn/Gln_tRNA_amidoTrase-B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023168">
        <property type="entry name" value="GatB_Yqey_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019004">
        <property type="entry name" value="YqeY/Aim41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042184">
        <property type="entry name" value="YqeY/Aim41_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28055">
        <property type="entry name" value="PTHR28055"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09424">
        <property type="entry name" value="YqeY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89095">
        <property type="entry name" value="SSF89095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="149" mass="15965" checksum="C59F3C5E2E504E21" modified="2019-11-13" version="1">MGLQEDVMTAIKAAMKAKDQTALAALRAVKSELLLAQTETGTKEEITEEQEIKILSKLVKQRKDSATIYSDQNRNDLAAPELAQAEIISQFLPAQLSEAEIENVVEATIAKVGASGMKDMGKVMGMVSQELAGKADGKTISTIVKSKLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJN9</accession>
    <name>A0A5C6ZJN9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type II toxin-antitoxin system HipA family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_05395</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012893">
        <property type="entry name" value="HipA-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07804">
        <property type="entry name" value="HipA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HipA_C" evidence="2">
        <location>
            <begin position="181"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="416" mass="47445" checksum="0A4489C41CFB7739" modified="2019-11-13" version="1">MATGKFDIYVFADWATLEKPTFVGVLSAHFAKGKKAFGFEYDKDWLKTDAQRILDPDIAFFSGPQYPTNKENFGIFLDSMPDTWGKTLMKRRAAQDARAKDEKQKTLYEIDYLLGVFDESRMGALRFKTDLEGPFLDNDAHTPTPPWSSLGDLQEAARQLESDEQNDEIRKWIAVLIAPGSSLGGARPKANIFDAQKNLWIAKFPSKTDTIDKASWEFLAYRLAVDSGIEMAESKIEKISGQYHTFLTKRFDRYNSRRIHFASAMTMTGNTEDSIKDTAPSYLEIVEFIENYGVDVEANLHQLWRRIVFNIAISNTDDHLRNHGFILTDKGWILSPAYDLNPSIEKDGLSLNIDMDDNALDFELAKSVGKYFRLSEKEMQTILDDVLSVVKNWKIMAKEIGIKNSEMQLMAGAFRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJV4</accession>
    <name>A0A5C6ZJV4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Geranylgeranylglyceryl phosphate synthase</fullName>
            <shortName evidence="9">GGGP synthase</shortName>
            <shortName evidence="9">GGGPS</shortName>
            <ecNumber evidence="9">2.5.1.41</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">(S)-3-O-geranylgeranylglyceryl phosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Phosphoglycerol geranylgeranyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ESY86_08520</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>(2E,6E,10E)-geranylgeranyl diphosphate + sn-glycerol 1-phosphate = diphosphate + sn-3-O-(geranylgeranyl)glycerol 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:23404"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57677"/>
            <dbReference type="ChEBI" id="CHEBI:57685"/>
            <dbReference type="ChEBI" id="CHEBI:58756"/>
            <dbReference type="EC" id="2.5.1.41"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the GGGP/HepGP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.41" evidence="9"/>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047294">
        <property type="term" value="F:phosphoglycerol geranylgeranyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046474">
        <property type="term" value="P:glycerophospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00112">
        <property type="entry name" value="GGGP_HepGP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038597">
        <property type="entry name" value="GGGP/HepGP_synthase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008205">
        <property type="entry name" value="GGGP_HepGP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010946">
        <property type="entry name" value="GGGP_synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01884">
        <property type="entry name" value="PcrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01769">
        <property type="entry name" value="GGGP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01768">
        <property type="entry name" value="GGGP-family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6 9" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 9" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="8 9" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <position position="21"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD89418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="242" mass="25859" checksum="6D56F8DC30EB77A7" modified="2019-11-13" version="1">MYKHLIERVAKGKKGLAVLIDPDKMAVGAVEAFVEKVESTIATHIFVGGSTVAPDATAPLILALKAFSKLPIVLFPGDVGQISNAADALLFLSLISGNNPEYLIGQQVKAVPKLRNSKLEIIPTGYILVENGKPTSVEKVTRTKPLPRKEIQTIADTAKAGELLGMHLIYLETGSGATHPVPPEIISFVKQDLNIPLIVGGGIKTKKQLDEAFEAGADLVVIGTAFEEDESFFLKLKKEPGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJW9</accession>
    <name>A0A5C6ZJW9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08635</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039426">
        <property type="entry name" value="BtuB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30069">
        <property type="entry name" value="PTHR30069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0675">Receptor</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023129552" evidence="1">
        <location>
            <begin position="23"/>
            <end position="1069"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1069" mass="116988" checksum="445608474FEF8C4F" modified="2019-11-13" version="1">MKKMNQILCLAVVLLISAASFGQGVTTASINGQITDANNEPLPGANVVAVHTPSGSTYGVAADFDGYYRMSNMRVGGPYKLTITYVGYQEFLKQDIYLQLGDSQQISVKLTEDASALDEVVITAQTNSLFDSGKTGAETTISNQQVTSLPTLSRGIADFVRLTPQAKVTGDDVISIAGQNNRYNAIYIDGAVNNDVFGLAPNGTNGGQTGVSPISLDAIESFQINVAPFDVRQSGFAGGSINAITKSGTNTFEGSAYSFYRDQSLAGKTPFDLAGEDGEREKLDDFTALTYGVRLGGPIIEDKLFFFINYERQDNETPQPFDIENYRGDVTAADLNNLSDFLQSNYGYNAGGYANNTSSLESDKLIAKIDWNINQNHKLSLKHSYVKAIQLDAPSSNSGRINFLNRAVNFESTTNSTALELSSTFGNKFANNLVIGYTSVDDNRDPNGSPFPSVEIRDAAGTSIFFGSEPFSTANLLEQRVLTFTNNFEIYSGKHTITIGTNNEFSSAKNVFFRQNFGDYRFNNLQDFLGGAKPNRYRYGYSLLGGTGDNSQGAAEFDLFQLGLYVQDEVSFSDSFKLTAGVRVDIPYWEDGLVNDDFNNRTIPLLEANGKDLQEARVGQGINANVHISPRVGFNWDVNNRNMTQVRGGVGIFTSRLPLVWPGGAYNNNGLTAGFIQLTGGNTPDFNPNPNTQFADPEPGSGAIGGQVDLFAKDFKLPQVFKTNIAVDQKLGAGFVLSAEFIWNDNINAVVYENINLQGPQFNTTGAGSRPNYGFRLIDDTYSDIYLGSNTGAGSSYNANMTLSNNYITDRLDIRSAVTYTYGDADVLLDATSSQNSSQWRNLETVNGSNRPVLSTSDFSPGHRVLANSSFEFKWSETIKTRIGLFYDGAEGSPFSYVYNGNNLLSDTGSDSALIYVPRDESEAQLVDTDDLTASQQYALLNAFIEGDDYLSSRRGQFAERNADRSDWIHIVDLKFAQEFGVKFGEKIHSLELTADIFNFTNLLNKEWGVRTFAGFNQVQLLDFERFAADGTTPLFSYDPRAADTVNIVDDSGLSSSRWQMQVGLRYSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK65</accession>
    <name>A0A5C6ZK65_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cyclase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_08705</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004061">
        <property type="term" value="F:arylformamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007325">
        <property type="entry name" value="KFase/CYL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037175">
        <property type="entry name" value="KFase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04199">
        <property type="entry name" value="Cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102198">
        <property type="entry name" value="SSF102198"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="249" mass="28418" checksum="A0BCBC88FA7B8E69" modified="2019-11-13" version="1">MIASINYQSRTRKIDLTKPLDISIPMRASKDNVNAWYIDAPKIEPVVIDEWKAAVVDGASINFNSINFNPHAHGTHTECVGHITEKVHSVNQNLKQFFFLAEVVTVAPERYMNDTMISKAQIKFALGNKKRDAIVIRTIPNMIEKKSKQYSHTNWPYLQEDAVAYLVQKGIKHLLIDQPSVDREEDGGELKSHKAFWNFEGKLRKDCTITELIYVPNSIEDGTYFLNLQIAPFENDATPSKPILYKIID</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK89</accession>
    <name>A0A5C6ZK89_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Sigma-70 family RNA polymerase sigma factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_07250</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="28"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="190" mass="22183" checksum="3959F09A5C198CAC" modified="2019-11-13" version="1">MSQVYKIQHQLQLINAIKDNDSLALKEFYMANYPKIEQLILKNSGSKAHAKDIYQEAFIAVWNNLRTGRFAPENDSALQGYLYQISKNKWLDVLRSKRFKSTQSLTEERSLFLSQDEETHEDPEETKRLNLAMEAFKNLGEPCKSLLKTFYFEQKSLRDIASEMAIEESSVRNKKYRCMEKLRSIVLASN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKC2</accession>
    <name>A0A5C6ZKC2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_04575</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023090686" evidence="1">
        <location>
            <begin position="25"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="159" mass="18486" checksum="7BE7D3256D90B398" modified="2019-11-13" version="1">MLLKLLPSMVFLLFVFGTSTHSYSQTDNQVKPLQQIFFDANVASPLTQKELGFIREVYGDNSESDILNRPQRLKDVKNILRNRVEFMHAPNKDLSSFAKLSSVPLFDFYNKSLTRDVILDKTNFNPLKYQFAFDSRQKTKMYLFDNSSYLVVIKSQNPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKK3</accession>
    <name>A0A5C6ZKK3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carboxypeptidase-like regulatory domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_02510</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043741">
        <property type="entry name" value="DUF5686"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18939">
        <property type="entry name" value="DUF5686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022666214" evidence="1">
        <location>
            <begin position="20"/>
            <end position="836"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="836" mass="95348" checksum="0D7FC4A74ED80973" modified="2019-11-13" version="1">MKLKLPILFFFFGMFSVFSQTKVSGYVFDEFDQPVAYANILFKGSTEGTISNEEGKFYLESDSTWKTLAVSFLGYETQEILLEKRVTYELKFILKEEAAALNEVLIVTGNQSKKASENPAIAILKKIWERKRKNGLRQFDQYQYDKYEKVEFDLNTIDSALIKSRIFKGMEFVFDKVDTSKVTGKTYLPIFINEAISKVYGDNLLNEEKEDLKGNKNSGFSNNQIIIEFVDDLYADFDIYDNYLKFFDKSFTSPLSKTGVNTYNYVLSDSAFIDNKWCYNIIYYPRRKNELTFKGDFWVNDSTYAIKDINLQASKSANINWVKEIYIEQEFEVVNDSVFLLKRDYMLSDFALNKKEKSRGVYGKRTTLYNNYVFDEPKDSDFYSQKVYSYNEDAYNRDDEFWDKNRMESLSQDERGVYKMLDTLKTVKKFKNLYSLGSILASGYIEVSSINTDIGPIFSVFGFNEVEGVRVRGGGRTYFGPNDLWRVEGYVAYGFRDDKFKYGISGKALLDIKNRLIISGGNRRDVEQIGANLTSSTDVLGRSLASSAVIGTSINDKLTSINLTTLGFELEPSKNFVVRTSGTYRTLESASPTFSLDYNDPEAVGGVSSDIQQYETALSFSYYPNRKMTGYGVERRVANDGFATLFAQVTRGDEGVFGSDFDYTKVQFSYIQPWLLGAYGRLTTTVEAGKTFGAVPLGLLSVVPGNQSYFSIYNTFPQLDFYEFVTDTYTSMHLEHNFNGRIFSRVPFLKKYNLRAIVGVRGVWGELSDENIALSTTGNPVEIPLIAPTDEVYYEYSVGVGNIFKILRIDFNFRGNYLDAPEARPFGVTGSFGFSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKK8</accession>
    <name>A0A5C6ZKK8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF3810 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024294">
        <property type="entry name" value="DUF3810"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12725">
        <property type="entry name" value="DUF3810"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="356" mass="41324" checksum="FA03A75719845C93" modified="2019-11-13" version="1">MPKKRKIILALSIIPQVLLIKVLALYPDFVEAFYSHGVYRYISKTLRYLLGWLPFSFGDLLYTFVIIYAIRWLILNGKRILRDFTNWILEVLSAVSIAYFAFHLLWAFNYYRLPLHQSLNIESDYTTAQLMDFTKQLIAKTNAIHFKITKDDSLKVTMPYSKSELLKKVPEGYEHLAKEFPYLAYSPSSIKRSIYSLPLTYMGFSGYLNPFTNEAQIDGLIPTYKYPTTGSHEVAHQLGYAAENEANFIGSMATMKHPDVYFKYSGHAFALRHCLGELYKRQPETYYEVLATINPGILKNYQEVQGFWDRYKNPTEPLFKSTYNNFLKANNQTAGMKSYSYVVALLVNYYEAHPLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKM1</accession>
    <name>A0A5C6ZKM1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aspartate aminotransferase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_03425</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="1 2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="396" mass="43084" checksum="43B1404F405F123A" modified="2019-11-13" version="1">MKDDFFKYQAQTTPHPLAMTVSHAEGSYIYDENQKAYLDFVAGVSACSLGHKHPKVIAAIKAQLDKYLHVMVYGEYVQETAVALSKLLASLLPDPLESTYLTNSGTEAIEGAIKLARRVTGRSEIISAHHAYHGNTMGAMSIMGYEARKAAFRPLIPDVNFIHFNDVSDLNKISSKTAAVVLETIQGGAGFIEPLNGYLQKVREQCDAVGALLILDEIQPGFGRTGKLFGFEHFNCVPDILVTGKGLGGGMPIGAFTASKAHMQLLQDHPKLGHITTFGGHPVIAAAALATVKEITESNLMAEALEKEQLIRTHLKHPLITEIRGRGLMLAAFTPSAEITNTVVLKAQDEGLILFWLLFEPKAIRITPPLTISKEEIIKGCHIILQILDGILAEEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKN3</accession>
    <name>A0A5C6ZKN3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">CHAT domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_07260</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026000">
        <property type="entry name" value="Apc5_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024983">
        <property type="entry name" value="CHAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12862">
        <property type="entry name" value="ANAPC5"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12770">
        <property type="entry name" value="CHAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022896755" evidence="3">
        <location>
            <begin position="20"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1046"/>
            <end position="1065"/>
        </location>
    </feature>
    <feature type="domain" description="ANAPC5" evidence="5">
        <location>
            <begin position="74"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="146"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="ANAPC5" evidence="5">
        <location>
            <begin position="422"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="CHAT" evidence="4">
        <location>
            <begin position="734"/>
            <end position="1034"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD89577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1073" mass="122353" checksum="3B57BD5B9A468CE9" modified="2019-11-13" version="1">MKGYSFCIFILMLSSLLQAQETPILNTSILDSLMLKGEILNAEARLNEQLAYIQSHNLNDSLYKYTYYVGKIELQKSDAKTASKKVDAFLDYINTKSKNKRSYYQALLKLADFYDEIGNNQKSLDITTTALKIIKEVRDATPEEIGKTEYNIGATYLSLGNVDQAKTNFQKALKRFESYKFTSKAQLSDGYNAVGATMWMSSKLDSASYYYSKAIEAIAMAKGDPIMNLYLATVIKSNISLLEYGQGNLDKAIAIQNGVISNYEKTIHALSDENVVSKAKRFQLRAISNMAVFYNEQGNLQKAHDLMLFAYQKKKTLREADDSDLGATLIQIGQSSLSLQNYDDAISYLNEGLKQFEVNAIENPYWKAAGFHALAEAHAVKKNTSEAKKYYEQSEQYFKEALGNDYDIEFLSFLRNKSLFLAENQAHEAALNTAQTGYDYVLKNGGDDNFTLVKQLLNLAMVNYKLQQYEQSLIWVDKANQYLNKAASAADSKQKDFHKPQLILLKALAQYELQPNKDTSFLKQQLIALDKAISLLEDRKTRVYKNEDLSILMTDYQSISNFSKKVALDLYQKTKEAIYLDKIIELNESAVYNRIRSRLNLKNSISFKDVSKPVLERELQLKNEMSFTLDHSENIQSFLDVEKEWQLFLDTLKTRFPKYYKMRYATISQPVKNLKRAIADHTTVVRYLNIDEATYAILINKSEKHLVRLNPKDLQKNVQALTNELWDLETSSELLHQLYVELWQPFEDRINTNHVIIIPNGQLFNLSFESLTPEKIASFKELETKSLLAKYIISYNYSLLLTNRTASQTLFSDNFIGFAPEFNSKMKTDYTLKIKDSITMDRTYLTLLPQPFSKNLAQNSSKFFTGESFINEKASKQLFTQHAKEHKIIHIGTHAESNNVSPELSRLIFAKNVKDSMASEDNSLYTYEIYNQNLSSNLAILTACETGKPTYQAGEGMISLAHAFNYAGSESILTSLWKIDEQSSAAIIENFYGYIKDGLPKDEALQKAKLDYIATAKGRTLSPQYWAGLVLIGDTLPIHLTSTSYFWYWMLGGLLVIFFLLVLLIKIKRSASH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKP5</accession>
    <name>A0A5C6ZKP5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">Glucose-inhibited division protein A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11 14" type="primary">mnmG</name>
        <name evidence="11" type="synonym">gidA</name>
        <name evidence="14" type="ORF">ESY86_08055</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 11">NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 11">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="9 11">Homodimer. Heterotetramer of two MnmE and two MnmG subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the MnmG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00129">
        <property type="entry name" value="MnmG_GidA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004416">
        <property type="entry name" value="MnmG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002218">
        <property type="entry name" value="MnmG-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020595">
        <property type="entry name" value="MnmG-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026904">
        <property type="entry name" value="MnmG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044920">
        <property type="entry name" value="MnmG_C_subdom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040131">
        <property type="entry name" value="MnmG_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11806">
        <property type="entry name" value="PTHR11806"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11806:SF0">
        <property type="entry name" value="PTHR11806:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01134">
        <property type="entry name" value="GIDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13932">
        <property type="entry name" value="GIDA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00136">
        <property type="entry name" value="gidA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01280">
        <property type="entry name" value="GIDA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01281">
        <property type="entry name" value="GIDA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11" id="KW-0274">FAD</keyword>
    <keyword evidence="5 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8 11" id="KW-0520">NAD</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="GIDA" evidence="12">
        <location>
            <begin position="7"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="GIDA_C" evidence="13">
        <location>
            <begin position="400"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="12"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="272"/>
            <end position="286"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF13932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TXD89735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="623" mass="69944" checksum="312661A7F34F400B" modified="2019-11-13" version="1">MFNETYDVIVVGAGHAGSEAASSAANMGAKTLLITMNLQNIAQMSCNPAMGGIAKGQILREIDALGGYSGIVSDSSAIQFKMLNKSKGPAMWSPRVQSDRMRFAEDWRLMLERTENLDFYQEMVAGLLVENHRVVGVKTSLGIEVKAKTVILTNGTFLNGLIHIGNKNFGGGRAGERAATGITEDLLNLGFESGRMKTGTPPRVDGRSLDYSKMTEQPGDEMPEKFSYLESIKPLTEQRSCHMTHTSKEVHDLLREGFDRSPMFNGQIQSTGPRYCPSIEDKINRFADKDHHQLFVEPEGWKTVEVYVNGFSTSLPEDIQFKALRSVVGFEKVKFFRPGYAIEYDYFPPTQLKHTLETKLVDGLFFAGQINGTTGYEEAASQGLMAGINAALKVQEKDEFILKRNEAYIGVLVDDLITKGTEEPYRMFTSRAEYRTLLRQDNADFRLTPKGYELGLASEARLKRMEKKQTESENFVDFFKDTSFSPEEANPILVAKDSAEVKQADKMFKLFSRPKISIEDMRQFNSVESYIQEHDLDREVIEQAEIQVKYAGYIKKEKNNADKLNRLEDVRIPDHFDYTKLKSMSTEGIQKLGKIRPVTISQASRISGVSPSDVSVLLVYLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKS5</accession>
    <name>A0A5C6ZKS5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ferrochelatase</fullName>
            <ecNumber evidence="6">4.99.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Heme synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Protoheme ferro-lyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">hemH</name>
        <name evidence="8" type="ORF">ESY86_07475</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the ferrous insertion into protoporphyrin IX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2 H(+) + heme b = Fe(2+) + protoporphyrin IX</text>
            <dbReference type="Rhea" id="RHEA:22584"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:57306"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="EC" id="4.99.1.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>Fe-coproporphyrin III + 2 H(+) = coproporphyrin III + Fe(2+)</text>
            <dbReference type="Rhea" id="RHEA:49572"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:68438"/>
            <dbReference type="ChEBI" id="CHEBI:131725"/>
            <dbReference type="EC" id="4.99.1.9"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="5">
            <dbReference type="Rhea" id="RHEA:49574"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Porphyrin-containing compound metabolism; protoheme biosynthesis; protoheme from protoporphyrin-IX: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the ferrochelatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.99.1.1" evidence="6"/>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00252">
        <property type="reaction ID" value="UER00325"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004325">
        <property type="term" value="F:ferrochelatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006783">
        <property type="term" value="P:heme biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00419">
        <property type="entry name" value="Ferrochelatase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03411">
        <property type="entry name" value="Ferrochelatase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00323">
        <property type="entry name" value="Ferrochelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001015">
        <property type="entry name" value="Ferrochelatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033644">
        <property type="entry name" value="Ferrochelatase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033659">
        <property type="entry name" value="Ferrochelatase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11108">
        <property type="entry name" value="PTHR11108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00762">
        <property type="entry name" value="Ferrochelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00109">
        <property type="entry name" value="hemH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="1 6" id="KW-0408">Iron</keyword>
    <keyword evidence="3 6 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6" id="KW-0627">Porphyrin biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="293"/>
        </location>
        <ligand>
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD89617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="345" mass="39456" checksum="E920F89ED6DD43C5" modified="2019-11-13" version="1">MNKKGVLLVNLGSPESPEPKDVKTYLGEFLMDERVIDVPYWARALLVKGIVLNTRPKASAKAYKKIWWDEGSPLIVLSERLQEKLQQEVEFPVALAMRYGSMTIKKGLQELADQGVDEVFLIPLYPQFAMATTETIVVLAEEVRKAHFPQMNIQELPAFYNEPEYIEVLANSIAKHLEGKDYEQLLFSYHGVPERHIRKSDITKSHCQIDGLCCKTPSPAHEFCYRHQCFEVTRLVGEKLKLKEGSFSTSFQSRLGFDPWLRPYTDRTIERMGKEGVKKMAIVTPAFVSDCLETLEEIAMEGEEIFHEMGGKDFTTIPCLNDDRAWVKLLAKWINEWSSTETITA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKS9</accession>
    <name>A0A5C6ZKS9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DUF1328 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_06765</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01361">
        <property type="entry name" value="UPF0391"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009760">
        <property type="entry name" value="DUF1328"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07043">
        <property type="entry name" value="DUF1328"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036466">
        <property type="entry name" value="UCP036466"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="5"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD89964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="53" mass="5727" checksum="67C76167C405FC31" modified="2019-11-13" version="1">MLKWLVICIVISIIAGIFGFAGIADAAAGIAKIIFVIFIIISIIVFLAFKKIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKX7</accession>
    <name>A0A5C6ZKX7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">APC family permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_02770</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="125"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="155"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="227"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="279"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="325"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="349"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="381"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="406"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD90897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="437" mass="46360" checksum="88A54315887355AC" modified="2019-11-13" version="1">MDNTYKKDSLSLIGAIALGTGVMIGAGIFALLGQVAELSGNLFPFAFIAGAIISGFSAYGYIKLSNAFPSSGGIAMYLVKAYGKGTIAASGALLMAFSMIINESLVARTFGSYTLQLFNVGDNSVWVPVLGVLLIVGAFLINISGNNIIGKSSLIMAIIKVGGIAIFAIGALWAVGFSFQDAISLNNSTDYPITDYLGALALSILAYKGFTTITNSGGEIVNPKKNVGRAIIISLLVCTVIYLLVAFAVSSNLTISEIVAAKDYSLAEASKPAFGKYGLWFTVGIAIVATISGIIASIFAVSRMTAMLTDMKLIPHKHFGMPGNVQKHMLVYVAVIAIALTIFFDLSRIASLGAIFYLVMDIGIQWGILRNLRKEVKANSAIIITAILLDVIVLSAFLWIKASSDITVIIVALVAMTLIISGERWFLKTNEQKQDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL38</accession>
    <name>A0A5C6ZL38_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">gldI</name>
        <name evidence="7" type="ORF">ESY86_04005</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 3 4">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the FKBP-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019869">
        <property type="entry name" value="Motility-assoc_PPIase_GldI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03516">
        <property type="entry name" value="ppisom_GldI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="6">
        <location>
            <begin position="88"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="33"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD90539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="177" mass="20229" checksum="3EA02394B16EC1EC" modified="2019-11-13" version="1">MKPTLYLILLVLFASCKSPDARRPESVKSGSFIKESAERNKKLNDKEQQLIEEIIAENSENNYIASNTGFWYHYNTKVEKDTITADFGDLVNFDYNLKDLKGRTIYASEELGNQDYVMDKEELFTGLREGLKLMKPGETVTFMFPSQKAFGYYGDKKRIGTNIPLISQVTVNAIKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL80</accession>
    <name>A0A5C6ZL80_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GIY-YIG nuclease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_00030</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035901">
        <property type="entry name" value="GIY-YIG_endonuc_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01541">
        <property type="entry name" value="GIY-YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00465">
        <property type="entry name" value="GIYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82771">
        <property type="entry name" value="SSF82771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="165"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="GIY-YIG" evidence="3">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD91024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="190" mass="20762" checksum="D1EFAFBC71BFB16D" modified="2019-11-13" version="1">MKGWMYILECSDNSYYTGSTNDLALRLKQHENGVGANHSKKRLPVKLLYTEEFPAIKAAHYREKQVQGWSRKKITALIKGDVGELTALAKNHTPLGNHSASAATNVAASEGSANENPVASAGSATEKSSSASEALAASKAQIKKDSTFSERWKTSRFWLIRGSYYVVHSVWLAVIAIGAFIAWVIAMLFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLE8</accession>
    <name>A0A5C6ZLE8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">23S rRNA (Uracil(1939)-C(5))-methyltransferase RlmD</fullName>
            <ecNumber evidence="7">2.1.1.190</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rlmD</name>
        <name evidence="7" type="ORF">ESY86_00845</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.190" evidence="7"/>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034470">
        <property type="term" value="P:ncRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030390">
        <property type="entry name" value="MeTrfase_TrmA_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030391">
        <property type="entry name" value="MeTrfase_TrmA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010280">
        <property type="entry name" value="U5_MeTrfase_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11061">
        <property type="entry name" value="PTHR11061"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05958">
        <property type="entry name" value="tRNA_U5-meth_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51687">
        <property type="entry name" value="SAM_MT_RNA_M5U"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01230">
        <property type="entry name" value="TRMA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01231">
        <property type="entry name" value="TRMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TRAM" evidence="6">
        <location>
            <begin position="3"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="428"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="428"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="302"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="331"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="352"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="401"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD91168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="470" mass="53622" checksum="C5B9DB38D37AECF0" modified="2019-11-13" version="1">MARKKTAKQIFENVSVVDAGAKGKTIGKAPDGRVIFMGNTVPGDVVDVQTFKKRKSYFEGKAIKFHTLSNKRTEPKCEHFGVCGGCKWQDMDYKYQLEYKQKEVTNNLMRIGHLELPEVTPILGSAEQYFYRNKMEFSFSDSRWLTQEEIQSNRDLGDRNALGFHIPGMWDKILDINKCWLQEDPSNDIRNAVKDFAVSNELEFFNTRQQTGLLRTLMIRTSSTGDLMVVVQFFKEDQEKRESLLDFMSDSFPQITSLQYIVNEKANDTIYDQDVICYKGKDHIFEEMEGLKFKINAKSFYQTNSAQAYELYKITRDFANLKGDELVYDLYTGTGTIAQFVAKQAKKVVGVEAVPDAITAAKENAQLNGIENVDFYVGDMKNVFNDAFIAAHGKPDVIITDPPRDGMHKDVVQQILNIAPNKLVYVSCNSATQARDLEMMKAHYKITKTQAVDMFPQTHHVENVVLLEKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLL7</accession>
    <name>A0A5C6ZLL7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Isoprenylcysteine carboxylmethyltransferase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_04885</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007318">
        <property type="entry name" value="Phopholipid_MeTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04191">
        <property type="entry name" value="PEMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="28"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="94"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD90307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="139" mass="16055" checksum="0AAD448C0B82E6A8" modified="2019-11-13" version="1">MVQLLIFVVYFLPIQLITIELPEWLSHLGLFILWIGLLFGIVALLQLNNKLSPFPSPVAAGKLITNGAFRISRHPIYTALIFSGFGYAVYQSSVYKILIAVLLLILFYFKSRYEEGLLSKKFSEYQNYKKRTRRFIGFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLL8</accession>
    <name>A0A5C6ZLL8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Deoxyribose-phosphate aldolase</fullName>
            <shortName evidence="3">DERA</shortName>
            <ecNumber evidence="3">4.1.2.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">2-deoxy-D-ribose 5-phosphate aldolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Phosphodeoxyriboaldolase</fullName>
            <shortName evidence="3">Deoxyriboaldolase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 4" type="primary">deoC</name>
        <name evidence="4" type="ORF">ESY86_00880</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>2-deoxy-D-ribose 5-phosphate = acetaldehyde + D-glyceraldehyde 3-phosphate</text>
            <dbReference type="Rhea" id="RHEA:12821"/>
            <dbReference type="ChEBI" id="CHEBI:15343"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="ChEBI" id="CHEBI:62877"/>
            <dbReference type="EC" id="4.1.2.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.4" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00002">
        <property type="reaction ID" value="UER00468"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004139">
        <property type="term" value="F:deoxyribose-phosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009264">
        <property type="term" value="P:deoxyribonucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046386">
        <property type="term" value="P:deoxyribose phosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00959">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00114">
        <property type="entry name" value="DeoC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011343">
        <property type="entry name" value="DeoC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002915">
        <property type="entry name" value="DeoC/FbaB/LacD_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028581">
        <property type="entry name" value="DeoC_typeI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10889">
        <property type="entry name" value="PTHR10889"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10889:SF1">
        <property type="entry name" value="PTHR10889:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01791">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001357">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01133">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00126">
        <property type="entry name" value="deoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0704">Schiff base</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with acetaldehyde" evidence="3">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD91174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="220" mass="24157" checksum="88CF618932D3895F" modified="2019-11-13" version="1">MNINSYIDHTMLKASTTERDIIDLCNEAKKHRFYSVCINGCYVSLAKQLLRNSNVKICTVVGFPLGASTTETKIFEAKQAIEQGADEIDMVMNIGFFKSQNYVEVYKDMTEIKTAIGIIPLKVIIEIDELSKNGVVKASEICMDANVDFIKTSTGFTKNGATLTAAKIIRKTVKNHCKIKASGGIADYETAKKYIDIGVERIGTSKGVDIAESELSGVNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLM4</accession>
    <name>A0A5C6ZLM4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_00935</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="137" mass="15654" checksum="E2F5E23E39326D8B" modified="2019-11-13" version="1">MKLSLYVLLIVLVTSCKAEKIDDSTSTAMNYRTYSIETLKQVSYTTRLIEGEFNQTFNELRFRQHHPDVLGEMSYLKDGRWDTLIPYRKKEPGILIWKNVAIGTIAGNLNIATTSYEDAYSAIMIFDENGKDMLAEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLS2</accession>
    <name>A0A5C6ZLS2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_02425</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022781165" evidence="1">
        <location>
            <begin position="24"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="197" mass="23419" checksum="4F91469775213DE0" modified="2019-11-13" version="1">MKSIYRLFTIGFLSLLFISTTKAQSEPTEYLSVGNKIEFNGENFELKWSSHPSNEYYKQEYLRKDDKLPRHEKMIMVEAVKGNIPAKNVVAGKINELENRKKRNPVVNYEKFENKENNEIILDFVLSDGKSVYEWNIYRYQNQNNESGNYLVLYSYSYRNYISNDKEKIKFLSEIKKLKEELIKKVEEIKLPDVKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLU2</accession>
    <name>A0A5C6ZLU2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidoglycan DD-metalloendopeptidase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_07610</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023125971" evidence="1">
        <location>
            <begin position="21"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M23" evidence="2">
        <location>
            <begin position="148"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="Por_Secre_tail" evidence="3">
        <location>
            <begin position="395"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="467" mass="52149" checksum="FD5463075B06DC82" modified="2019-11-13" version="1">MKSQITILLLALLGVNIAKAQSPETPVNGSAYVFNAEKSPCLTNEARKSIIQELENNVAMLQNEQRLNYNGTHRDGHVLFSWPVQKADGIDFNDVWSISGYLDHNAAYPNQLTDYDCGTTTYDTSAGYNHQGVDIYTWPFPWKLMDDDSAEIIAAADGQIIAKGDGQYDRSCNFNSNPWNAVYVQHSDGSVAWYGHMKNGSLTTKSVGDMVAEGEYLGIVGSSGNSTGPHLHFEVYEDNSYTQLIDPFAGDCNSLNGNDSWWVEQKPYLKPNINAVMTHSQVPDLFPTCPTTETTFESSAFDISDTIYFTAFLRDQVVDDVIYLKAIRPNGTYLYDWNITVVTSASSWYYYWSFPVDAVGEWTWEVTFKGQTETTNFTVSDALNLDESSFSQTSVYPNPFYDVLQIRSKVPVTKAIVVDVLGKMIKRSSNISEGIQHINLETLSAGLYFLTLEGNDGQQKTIKLLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM37</accession>
    <name>A0A5C6ZM37_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase family 9 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03789">
        <property type="entry name" value="GT9_LPS_heptosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002201">
        <property type="entry name" value="Glyco_trans_9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01075">
        <property type="entry name" value="Glyco_transf_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="330" mass="36928" checksum="18A84EED5E8FA18D" modified="2019-11-13" version="1">MGDVAMTVPVLRALVAQYPEVRLSVLTRAFFKPFFRDLPNVSVFEADLKGRHKGLFGLWKLSQELRALGFDAVADLHNVLRTKILKCFFFGRKVVQIDKGRAEKKALVTGQKFEQLKTTHERYADVFEKLGFPLDLSNPSFPERARLSPELLEILGTDTKKWIGIAPFAAFSGKMYPIDLIEKVIEILSKTYKVILFGAGKDEILLIKKLLKGKANSINLAGQLAFSEELDVISNLDVMLAMDSGNAHIAAMLGVEVVTIWGVTHPFAGFYPFNQSKNNAILADRKQFPQIPTSIYGKDYPKGYDKAMRNISPEQVVSKINSILENSAFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZME9</accession>
    <name>A0A5C6ZME9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF2652 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_01265</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020503">
        <property type="entry name" value="Uncharacterised_Rv2561"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10851">
        <property type="entry name" value="DUF2652"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="196" mass="22551" checksum="8E40ED0499E77454" modified="2019-11-13" version="1">MINRPTLICIPDISGFTKFMSETNSDLSHKVVSSLLNKIIYTNTIDLKVSEIEGDAIFFYLPGELPSFEILLKQCRHFHDEFYKQLKNLTNQNSGNEDSENINHMLGLKIILHYGEHVEAVQIGSRIKLMGEDVIIAHRLMKNAIKEDEYILFSNGLLDQYEKAQLADNMDLKQLKSGKNNYKHLGEVNYKYIVLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMH4</accession>
    <name>A0A5C6ZMH4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tyrosine-type recombinase/integrase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_04360</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="2">
        <location>
            <begin position="24"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="100" mass="11637" checksum="9FD0360A7A3F622C" modified="2019-11-13" version="1">MVFDIVTQTEGSETQYKKIKNFNRYINDHIKRIAKANELPEDCSFYWARHSFATNSIRKGASMEFISEALNHSDLNVTKNYFAGFEDKAKKEFANSLLDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMI2</accession>
    <name>A0A5C6ZMI2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AAA family ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_06550</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011703">
        <property type="entry name" value="ATPase_AAA-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041628">
        <property type="entry name" value="ChlI/MoxR_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07726">
        <property type="entry name" value="AAA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17863">
        <property type="entry name" value="AAA_lid_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_3" evidence="1">
        <location>
            <begin position="44"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="AAA_lid_2" evidence="2">
        <location>
            <begin position="248"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="317" mass="35064" checksum="BA4707DBBA7F9D0A" modified="2019-11-13" version="1">MSDVAAIENFVKKYNALKSEVAKVIVGQDEVVNQILISIFSGGHSLLIGVPGLAKTLMVNTIAQALGLDFKRIQFTPDLMPSDILGSEILDENRHFKFLKGPIFANIVLADEINRTPPKTQAALLEAMQERAVTVSGHQYQLSLPYFVLATQNPIEQEGTYPLPEAQLDRFMFAINLEYPSFQEEVQVVKTTTTDVTQTVNALFTAQEIIDFQNVIRRIPVADNVIEYAVTMVSKTRPNTSYASDLVTEFVDWGAGPRASQNLILAAKTHAAINGKFSPDIENVQAVAQGILRHRIIKNYKAEAEGVSDQQIIESLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMJ6</accession>
    <name>A0A5C6ZMJ6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fumarylacetoacetate hydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03965</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="SSF56529"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAA_hydrolase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="203" mass="23104" checksum="C00A2B10AD72E166" modified="2019-11-13" version="1">MKLICIGRNYAEHIEELKNERPSDPVVFLKPDTAILLKKQPFFIPDFSDDVHHEVEVLVKINKVGKHIDKRFAHKYYDEIGLGIDFTARDLQSQLKEKGLPWEKAKGFDGAAVIGDWLPKSGITDVNHINFSLKKNDILVQKGNTSHMLWKIDEIIEYISKYFTLKIGDIIFTGTPSGVGRVNTDDKLTGFLEDKAMFSITVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMU5</accession>
    <name>A0A5C6ZMU5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">TetR/AcrR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_01960</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041490">
        <property type="entry name" value="KstR2_TetR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17932">
        <property type="entry name" value="TetR_C_24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="5">
        <location>
            <begin position="4"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="4">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD90750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="190" mass="21593" checksum="06DD50A86247E46D" modified="2019-11-13" version="1">MKSETRKNDIIKTAAKLFKSKGYSAVTMRDLATAMDMKAASLYNHISSKQELLKTIVVFIAEEFTNGMRQIQASEKSNIAKLKAIVALHVEITAKHTNGMAALNNDWMHLEDQLEHYLQLRTEYETSFLDIIEHGIASEEIKPSNPEIIMFSMLTTLRSLYLWMPKKGRLNSQELSQNLSDIMIDGIIKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN00</accession>
    <name>A0A5C6ZN00_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TlpA family protein disulfide reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_02345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013740">
        <property type="entry name" value="Redoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08534">
        <property type="entry name" value="Redoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="93"/>
            <end position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="241" mass="28382" checksum="85E447041C126C4E" modified="2019-11-13" version="1">MKKLTLILALFSLLRLSAQDKEIIYRQADGKLMTESQYLKMKNNFKDKMKKQGKTGEVKEEIKDSIAHQTTYKNFKLFFVEITETTKKERIDTYIDKKFPSNELLTLESEKFSFSGLEGKPTFISFWFIQCAPCIKELPALIELKKKYGDRVNFVAITFNDAKEVESFLEKREFDYKHIVNADDFINDIGLNTYPRNIFMDKNGTIRAIKNEIPYEEKTKNKKVELEFDLSEFEKQLENLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN17</accession>
    <name>A0A5C6ZN17_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">3-phosphoshikimate 1-carboxyvinyltransferase</fullName>
            <ecNumber evidence="4">2.5.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">5-enolpyruvylshikimate-3-phosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ESY86_02455</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>3-phosphoshikimate + phosphoenolpyruvate = 5-O-(1-carboxyvinyl)-3-phosphoshikimate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21256"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57701"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
            <dbReference type="EC" id="2.5.1.19"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the EPSP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.19" evidence="4"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00089"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003866">
        <property type="term" value="F:3-phosphoshikimate 1-carboxyvinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.65.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001986">
        <property type="entry name" value="Enolpyruvate_Tfrase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036968">
        <property type="entry name" value="Enolpyruvate_Tfrase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006264">
        <property type="entry name" value="EPSP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023193">
        <property type="entry name" value="EPSP_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013792">
        <property type="entry name" value="RNA3'P_cycl/enolpyr_Trfase_a/b"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00275">
        <property type="entry name" value="EPSP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000505">
        <property type="entry name" value="EPSPS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55205">
        <property type="entry name" value="SSF55205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00885">
        <property type="entry name" value="EPSP_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="EPSP_synthase" evidence="9">
        <location>
            <begin position="57"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD90840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="408" mass="44582" checksum="B73C3CE9A0166002" modified="2019-11-13" version="1">MTISLQKSSIHKTNSLTITGSKSESNRLLLLQALFPELTIENVSNSDDSHVMQQALETTSEIIDIHHAGTAMRFLTAYFASKSGSEVVLTGSPRMKERPVEILVEALTHLGADIAYLETEGCPPLRIKGKHLTQSKVSLNANVSSQYISALMLIAAKLENGLELTLKGKITSVPYIEMTLALLKQVGIEASFNGNLIKIVPQVSTLNPQTLVVESDWSSASYFYSIVALSAVGTNIRLSSYKKDSLQGDSVLASLYESFGVSTVFENEQIQIKKVSEAIKEPINFQLNHAPDIAQTIAVTCLGLGISCHLSGLHTLKIKETDRLLALKTEIEKLGGSVHITENSLALEVTKHINFDVSIATYNDHRMAMAFAPMALKTKLNIEDANVVSKSHPSFWDDLKNLGFKITQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNC9</accession>
    <name>A0A5C6ZNC9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_02365</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009091">
        <property type="entry name" value="RCC1/BLIP-II"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50985">
        <property type="entry name" value="SSF50985"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023147024" evidence="1">
        <location>
            <begin position="23"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="260" mass="30308" checksum="0ADCD57B4AE3723B" modified="2019-11-13" version="1">MNLSKLFLLLFCASCFSQTSIKATFIDATALTADHLIAIDNFGTLYYTKNNIFNQVKANKPALNYSNVQLGIITSVNAFNPLKINIFYQDFNTVVILDNRLAEIYKIDFNTIQPYKNVTHISTGYDNTIWIFNQDLQQLELFDYKTERIRVTTIPVQSNVLDLKSDYNHCWMLTEKFLYQYSYFGSLISKIKNEGFKAIAVENENCLIQTSDSYLYKAKDREDLIPLAMPKLLINQFLLANQTLYIYELDRLHRYQLKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNG9</accession>
    <name>A0A5C6ZNG9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2752 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00830</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021215">
        <property type="entry name" value="DUF2752"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10825">
        <property type="entry name" value="DUF2752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="92" mass="10362" checksum="3C10E42BC5AA676E" modified="2019-11-13" version="1">MSPEDYMLPCLNKQILGFECTGCGMQRALALIYNGEFIAALQMYPAIYTLIFFFAFIIVNAFAHFKYANKIIVILALTNVVVIIGSYLIKII</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-02-10" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNH9</accession>
    <name>A0A5C6ZNH9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Histidine phosphatase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00885</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002918">
        <property type="entry name" value="Lipase_EstA/Esterase_EstB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01674">
        <property type="entry name" value="Lipase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023142114" evidence="1">
        <location>
            <begin position="20"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="168" mass="19008" checksum="8DBC77E8CFB213AA" modified="2019-11-13" version="1">MKLFFILTFTFLFGMNSQAQNEATHVTTYYLIRHAEKDRSDGGNKNPNLNNDGQKRAQLWRYYFKNIKLDAVYATNYNRTKQTAKPIAESKELEIQIYDANDLFSEAFKEATKGKSVLVVGHSNTTPAFANAILGKQSHDDLNDGDNSKLFVITISGGEVFQELLTIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNU7</accession>
    <name>A0A5C6ZNU7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ParA family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00615</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_31" evidence="1">
        <location>
            <begin position="2"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="254" mass="27893" checksum="E9C4ECECCDD7C603" modified="2019-11-13" version="1">MGKIIAIANQKGGVGKTTTSVNLAASLGVLEKKVLLIDADPQANATSGLGIDVETIEVGSYQLLEHTAKAEDCIISTDSPNVDIIPAHIDLVAIEIELVDKDQREYMMKQAISHLREQYDYILIDCAPSLGLLTLNALTASDSVIIPIQCEYFALEGLGKLLNTIKSVQKIHNKDLDIEGMLLTMYDQRLRLSNQVVEEVQKHFSDMVFETIIQRNVRLGEAPSYGESIIKYDVSSKGASNYLSLAKEIINKNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPJ5</accession>
    <name>A0A5C6ZPJ5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_01350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022816361" evidence="1">
        <location>
            <begin position="21"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="304" mass="32444" checksum="A4BE8ED6756C1AC0" modified="2019-11-13" version="1">MKSILALFSVILLSTTAAFAQVGIGIETPDASTILHLESTNSGLLLPRLTTAERDDIFTIGPGPANGLTIYNTTTSAVEINIGTSAAPNWSLLTTSTTTGPVLAPSYTTTQMIALPSTPGSLIYNTTESCLFQYKGAPFNTWQSLCEAESSKIVTLYSASPGIIDGDSDFHNFPLGTGDVQEIDEDYYEVDPLVKGRIKVLKAGNYLINASWGIANLKSGTRKYILAVFEGSTRRGYMNRGFAVIPGASTVTDEFGVSGAFQYEFAANAIINVQYYIDNTNQTGQSGGTTDLTGDEMHIGIIKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPY2</accession>
    <name>A0A5C6ZPY2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Four helix bundle protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_01865</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16377">
        <property type="entry name" value="23S_rRNA_IVP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012657">
        <property type="entry name" value="23S_rRNA-intervening_sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036583">
        <property type="entry name" value="23S_rRNA_IVS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38471">
        <property type="entry name" value="PTHR38471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05635">
        <property type="entry name" value="23S_rRNA_IVP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158446">
        <property type="entry name" value="SSF158446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02436">
        <property type="entry name" value="TIGR02436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="123" mass="14366" checksum="2B6C972EA38BFA62" modified="2019-11-13" version="1">MQFESKYHFSFENLIVYQKAIVFGEQIDKLVKTFPKDEMFRLSSQFSRAADAIPANISEGSASTDPNFNRYLKMAWDSSHECVTWNTKAYLRKYITMEEFEANRELLTEIGKMISSLRKKLTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZQX3</accession>
    <name>A0A5C6ZQX3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glucose 1-dehydrogenase</fullName>
            <ecNumber evidence="1">1.1.1.47</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_01545</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.47" evidence="1"/>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047936">
        <property type="term" value="F:glucose 1-dehydrogenase [NAD(P)] activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="245" mass="26228" checksum="9A58BB8806CBAA8D" modified="2019-11-13" version="1">MRLKDKIAIITGGSQGIGKAISELFAKEGATVIIMDVLPKGEEVANEISESGGKAEFHKVSVTDKISVEKLFEQVNSKYGKIDILINNAGITRDRTLEKMSEAEFDAVIEVNLKGVFICTQAVAPYMKANNYGRIVSAASNVGLRGNFGQTNYAATKAGVIAMSKTWTMELGKYGITANAIAPGFTMTDMVDKIPEAQLEAIKGSIPLKTVAQPIDIAYGYLYLASDEARFVSGICLTIDGGTSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAM5</accession>
    <name>A0A5C6ZAM5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4375 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000086">
        <property type="protein sequence ID" value="TXD86178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025402">
        <property type="entry name" value="DUF4375"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011652">
        <property type="entry name" value="MORN_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14300">
        <property type="entry name" value="DUF4375"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07661">
        <property type="entry name" value="MORN_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4375" evidence="1">
        <location>
            <begin position="38"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="388" mass="45930" checksum="6C273772CE4D0587" modified="2019-11-13" version="1">MDKGEFFKLTGFDFGWYVLEPISEYIKDRKGELKKGKTLSYGQKALYYWWYVDAQVNNGGFTQFYYNDYGKYVPTIIKGLKHIGDDKMAELVNRSYELYLKENKKIKDARKGGLQAFSNLYKEIEDFDELDDEYYELNEQTMKIIEKYIRNNSNEICRDEDGNEFDLNYSGELKTYHPNKSIKEIIPLENGTISGTFRSYFENGQLKDEIHYLNGEQTGKRTEYYENGSNKFSITKSQNPKGNLHSHYYENGNLKSTEIYVPQNDRDGKWIQYYPNGQMKSETEFINKEFFVQNCWKEDGSQIMKDGTGLYINEYSIFDGVTDRNEQEYKNHKRHGKQYSYSNDRLTLYQEMSEGKEHGVTKTYDDEGNLKEEIIYENGIEKSKKKYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAN1</accession>
    <name>A0A5C6ZAN1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19525</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000041">
        <property type="protein sequence ID" value="TXD86731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="158" mass="18082" checksum="9B3E90A9CB59DB50" modified="2019-11-13" version="1">MKRLIGFMVMVCLMSCDYFDKKKVNTEQLLQEELKTFNWKDVDEYPSFDSCDSAVEKADKKACFESTLRAILNKNLANQTIIVSEDINDTVFLKITIDRHGVFAINSILSTKRLETEIPQLDSLLRSSLDSLPKIYPAIKRSQQVATQFTLPVLVQIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAQ4</accession>
    <name>A0A5C6ZAQ4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribose-phosphate diphosphokinase</fullName>
            <ecNumber evidence="1">2.7.6.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Phosphoribosyl pyrophosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_18485</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.1" evidence="1"/>
    <dbReference type="EMBL" id="VORO01000031">
        <property type="protein sequence ID" value="TXD87045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004749">
        <property type="term" value="F:ribose phosphate diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009165">
        <property type="term" value="P:nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009156">
        <property type="term" value="P:ribonucleoside monophosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000842">
        <property type="entry name" value="PRib_PP_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029099">
        <property type="entry name" value="Pribosyltran_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005946">
        <property type="entry name" value="Rib-P_diPkinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210">
        <property type="entry name" value="PTHR10210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14572">
        <property type="entry name" value="Pribosyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13793">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01251">
        <property type="entry name" value="ribP_PPkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00114">
        <property type="entry name" value="PRPP_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran_N" evidence="8">
        <location>
            <begin position="9"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013247"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00029942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD87045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="313" mass="34261" checksum="59736B849658AEED" modified="2019-11-13" version="1">MPTGATEAKIFACTQSKELAEKIAAKYGAPLGNVITSTYSDGEFQPSYEESIRGIRVFIIGSTHPGPKNLMEMLLMIDAAKRASARHITAVLPYFGWARQDRKDKPRVPIAAKLVAKMLEAAGATRIITMDLHADQIQGFFEKPVDHLFASTIFLPYLKSLNLDNLTIASPDMGGSKRAYAYSKALESDVVICFKQRAKANVISHMELIGDVTGKNVVLVDDMVDTAGTLTKAADLMMEKGALSVRAICTHPILSGDAYEKLENSKLEELIVTDSIPLKQKSDKIRVLSCADLFAGVMQNVHYNKSISSQFLM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAS0</accession>
    <name>A0A5C6ZAS0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000075">
        <property type="protein sequence ID" value="TXD86282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023016498" evidence="1">
        <location>
            <begin position="31"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="211" mass="24702" checksum="0CA07835EA30BDCB" modified="2019-11-13" version="1">MNKSQKLNSAATLYILITLTMFSLQTSVFAQGNEKLDYIVLYVGDTLHGKVQYIDEGIPREFYKKIRLTTSDGKGKKYKRKNVASFRVTNITYESFWLSQTSQRFSLVNPKYNIDHNNGEQYFLKVVSKGNLNHYELEWIEQGDTALRSMALLKKEEDPFFIRADQGVIRLKRKVLLDYFSNCPRIIEAINQKQIKDVWQVVDFYNKNCID</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBD6</accession>
    <name>A0A5C6ZBD6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000035">
        <property type="protein sequence ID" value="TXD86898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="210" mass="23580" checksum="D5788664BF618541" modified="2019-11-13" version="1">MESKNYLQDISDIKSMMHKSSRFLSLSGLSGIMAGIYALIGAFLGYHIIYANNIISADGYRTIILTQKHMIEIIVVAFAVVLLSLITGIVLSYAKAKKQNESLWDATSKRLLINFLIPLATGGFFIMFLLEKNIFAFVAPMTLVFYGLACVNASKYTLGYIRYLGITMIVIGLLSVYFLGYGLFFWALGFGVCHIVYGTIMHFKYDRIRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBK8</accession>
    <name>A0A5C6ZBK8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Site-specific DNA-methyltransferase (adenine-specific)</fullName>
            <ecNumber evidence="3">2.1.1.72</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_19590</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:15197"/>
            <dbReference type="Rhea" id="RHEA-COMP:12418"/>
            <dbReference type="Rhea" id="RHEA-COMP:12419"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90615"/>
            <dbReference type="ChEBI" id="CHEBI:90616"/>
            <dbReference type="EC" id="2.1.1.72"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the N(4)/N(6)-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.72" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000043">
        <property type="protein sequence ID" value="TXD86694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1020.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023095">
        <property type="entry name" value="Ade_MeTrfase_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012263">
        <property type="entry name" value="M_m6A_EcoRV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012327">
        <property type="entry name" value="MeTrfase_D12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30481">
        <property type="entry name" value="PTHR30481"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02086">
        <property type="entry name" value="MethyltransfD12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000398">
        <property type="entry name" value="M_m6A_EcoRV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00505">
        <property type="entry name" value="D12N6MTFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD86694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="320" mass="37673" checksum="21DDBBEB589D35E3" modified="2019-11-13" version="1">MGVNLSTKHYSPLRYPGGKAKLSYYVQLLIDYNLINDGHYVEPYAGGASVALSLLFNEFVSEVHINDFDVRIYSFWNSILENTDEFIEKIETTELNIQNWKKQKIIQQNFQDYTEMEVGFSTFFLNRTNRSGILKAGVIGGKNQDGKWKMDARFNKKNLIERIKKISRYKNRINLYNEDAVDLTQKLNKTLPQQTLFYFDPPYYNKGKDLYINFYEHADHKQIAEIISKLKNRYWLVSYDNDKNISDLYSKFLQRTYQLNYHANNATKGTEIMIYSDNLIVPEMNSPVDKTELKEFNEDGLNADWINQRNNTVPNNVYKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBU5</accession>
    <name>A0A5C6ZBU5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF3857 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19185</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000037">
        <property type="protein sequence ID" value="TXD86821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024618">
        <property type="entry name" value="DUF3857"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12969">
        <property type="entry name" value="DUF3857"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3857" evidence="1">
        <location>
            <begin position="26"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="610" mass="70436" checksum="4F9B9A95B7A59E25" modified="2019-11-13" version="1">MVSLKEKTVTEFYFEEDGSLTEYFLEHNVYYLNADDAIERYNKVYLPYASDSNLERNKARVITPSGKVIHLDDSKIMTATNEETNRAYKYFAFEGIEKGSIIEYLYVVKRFPVYKGKRIDFQADFTKNNVEFDLLAPSNLLFRFKSYNGLAQVERDTLSKNKLHWSLKVPQIPLLEEEELAAYEADKKFLIYALDENTASRTKDISSYANVAQYIYENYNTELSRREQSKLEDFLKQIDFNEADALDAKLRAIEFYVKTNLYIASGGDEKLSALEDVLKDKVANESGIVKLYTSIFNALNIEFEFIYTCERSYMRFDTDFEANNFLTDVLFYFPKTKKYMSPTEMESRYGFPPAFLTDTYGLFIKEVVIGDFKSAVAAIEFIKPVAAENNTDTMRIEVAFDAEDLTKTHVKLDKSLSGYYAMYIHPYMDLIKPENKDELIEGFAKNIDDDAEIIEKAVNNGQSKLFGTKPLQFVLDFDSEAFVEKAGGKYLFKVGDLIGRQMEMYQDKKRSLPVENEFQRSYYRTISIAIPEGYEVANLEDINIENVYETNGEELLSFKSHYELNGSNLIITANEHYRVNHIAAAIYEAYRTVINSAADFNKITLVLEPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBW8</accession>
    <name>A0A5C6ZBW8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HRDC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000029">
        <property type="protein sequence ID" value="TXD87121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010997">
        <property type="entry name" value="HRDC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002121">
        <property type="entry name" value="HRDC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044876">
        <property type="entry name" value="HRDC_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00570">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47819">
        <property type="entry name" value="SSF47819"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50967">
        <property type="entry name" value="HRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HRDC" evidence="1">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="42" mass="4768" checksum="A48809D8878F6B54" modified="2019-11-13" version="1">MERGLKTFHVFGNTTLHEMVNSKPKTKAELIDVKGIGERKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC00</accession>
    <name>A0A5C6ZC00_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_17260</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000026">
        <property type="protein sequence ID" value="TXD87311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="272" mass="31246" checksum="9D64FE5E7C81B9B5" modified="2019-11-13" version="1">MEPKFKIFFVLSLFFAYSEQIYSQGIIDGFYKQQKEASLVLGYGFANNSDYLIGREASNLNRKLSYTSLFTSYGITDQLNIQVSLPYIESETNMDFQDLSLFSKYKVYSKQNENNRIELSLALGFSTPLSNYAIGGLYDIGQQASIIDTRAMLHYQLKSNWFTTIQSGFSYKLQEVPNSIPAVIKLGRATKSWYYDLYYEMQHSLGGIDYRGTPRPQNFRELRVNFQKVDATLYKPIYEELGAFGSFAYVLDGRNTFQGPSYGFGLVYAFKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC68</accession>
    <name>A0A5C6ZC68_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_20030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000055">
        <property type="protein sequence ID" value="TXD86502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="152" mass="18307" checksum="DA7340DCAB69677F" modified="2019-11-13" version="1">MPLTKDWKLDSTILKSPFRGLYVPYVPLDRNDTTYGFLENRGYCHYWNNKKVNKSKPYLRNKEIHFTKSYWLWKNELSFEINYYVNPTTEIGDYLQLETVSLLKHNELLSARITQFKNGEEFFIFENSVLNDKMFGKEEKTVDSILKKWKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC85</accession>
    <name>A0A5C6ZC85_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Winged helix-turn-helix transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000051">
        <property type="protein sequence ID" value="TXD86570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01022">
        <property type="entry name" value="HTH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="26"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="123" mass="14046" checksum="2ED8043CCA7B304F" modified="2019-11-13" version="1">MKLEITCTRAEANLKQLQNCMETLDKMEGSFQKITKLLSLAGNDVRLKILFLLNKENELCPCDLADILKMSVPAVSQHIRKMKDAAIITARRDGQTLYYSLNEDETDILNNIFKSIKLERKIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCD2</accession>
    <name>A0A5C6ZCD2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19385</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000039">
        <property type="protein sequence ID" value="TXD86771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="94" mass="10734" checksum="4F8BE19F7542448F" modified="2019-11-13" version="1">MENTNIGSSTTNETSTQVYGFKASRFENKQARFNRNRRFSEAIVGVFHQQSQPSKTKADLNLDSGFSKAIVGVFHQQSQQSKTRVNLNRNYLFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCJ7</accession>
    <name>A0A5C6ZCJ7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">TIGR03643 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_17330</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000026">
        <property type="protein sequence ID" value="TXD87323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019882">
        <property type="entry name" value="CHP03643"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10985">
        <property type="entry name" value="DUF2805"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03643">
        <property type="entry name" value="TIGR03643"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="91" mass="11171" checksum="41D9B8489206E23F" modified="2019-11-13" version="1">MKDLSLRETDRIIEMAWEDRTTFEAIEFQFDLNEQDVIALMRKEMKPSSFRMWRQRVQGRKTKHEKLRTFEKGRFKCSRQKQITNNSISKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCQ3</accession>
    <name>A0A5C6ZCQ3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17535</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000027">
        <property type="protein sequence ID" value="TXD87237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="242"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="300"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="338"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="390"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="437" mass="48568" checksum="988C7EB612D65903" modified="2019-11-13" version="1">MNHLPLIIKREYLTKVRNKSFIVMTFVSPLVGVALIAVVAYLSQLNNDKLRSIAILDDTGLVSGLFENTEYTSYKVLDGITLESAKELVETDGDFGLLYISKSKDSLNVVDRVRFFSDESPSLSIISGLERKIEKKLSETKLQLDGMDLDKIKASITSVNIAQETFSGQKTSKLDSYLKLGFGGAAGYLLFMFIIIYGNMIMRSVIEEKTSRIIEIIISSVKPIQLMMGKIIGTSLAGITQFAIWLVLGGILVFALTAILGISIADLQTPQQQMMQDAMANPTVSNEVQLAIQSFFNLPLANLMIAFLLFFIGGYLLYSSLYAAVGAAVDNETDTQQFMLPIIMPLILSVYVGLFTVIEDPHGTVSTVFSFIPFTSPVVMLMRIPFGVPIWQQVLSLAILLSTFAFTVWFAAKIYRVGILMYGKKPSYKELFKWLRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCT3</accession>
    <name>A0A5C6ZCT3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF2132 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_16340</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018668">
        <property type="entry name" value="DNA-binding_VF530-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09905">
        <property type="entry name" value="VF530"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="74" mass="8796" checksum="CFF6883147FAF6FE" modified="2019-11-13" version="1">MESQPNNPLHGVTLEQILTELQAHYGWEYMGTIVKINCFKSNPTVKSSLKFLRRTPWARTKVEQMYLKMLERQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCZ4</accession>
    <name>A0A5C6ZCZ4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">RNA-binding S4 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_18670</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HSP15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000033">
        <property type="protein sequence ID" value="TXD86952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003727">
        <property type="term" value="F:single-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034605">
        <property type="term" value="P:cellular response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025708">
        <property type="entry name" value="HSP15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016821">
        <property type="entry name" value="HSP15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S4" evidence="4">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="100"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD86952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="126" mass="14938" checksum="FF93EFDF4A9AA4D7" modified="2019-11-13" version="1">MRVDKFLWCIRYYKTRSIATTACKKGQVKVNEQVVKPSRDVFPLDKIELRKDQIKYQLTINDLPPNRVGAKLVDIYRTDTTPKEAFEAQKLLKYSKDYYRKKGTGRPTKKDRRDIDDFYDAPKVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD71</accession>
    <name>A0A5C6ZD71_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">FecR family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_18585</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000032">
        <property type="protein sequence ID" value="TXD86998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006860">
        <property type="entry name" value="FecR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032508">
        <property type="entry name" value="FecR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012373">
        <property type="entry name" value="Ferrdict_sens_TM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30273">
        <property type="entry name" value="PTHR30273"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16344">
        <property type="entry name" value="DUF4974"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04773">
        <property type="entry name" value="FecR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="FecR" evidence="2">
        <location>
            <begin position="180"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4974" evidence="3">
        <location>
            <begin position="318"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD86998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="389" mass="44115" checksum="155A71DE54C9759C" modified="2019-11-13" version="1">MTLLDKIYQLTKKLSKALLDNKGFGDLDESDLFSDDAKKHIKQHLSEEEIKENLELLNKIDKELGWEHVENRISHYGKVKSNKRLSKSSFYKIAAVAVLFISIGYIAYNGLTNETLLEVEQVNFPAGKNKAILTLEDGVDVALEKERPFKKGAVHSNGERLKYSKTSTNSKIAFNYLTIPRGGQYQIELSDGTIVWLNADSKLKYPVAFKSGTTRTVELLYGEAYFDVSPSTSHNGDTFKVLTKDQEVEVLGTKFNIKAYNDERYIYTTLVEGQVNILVNGLLTRLSPSEQTALNIDTQQLTKSIVNVDYHIAWINGYFNFKDTSLKEIMQVISRWYDVDITFESQALEDVRFSGLLSKTQNIEDILNGIQSTKFINAYGIENKTIIIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD84</accession>
    <name>A0A5C6ZD84_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF808 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_16740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000024">
        <property type="protein sequence ID" value="TXD87427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008526">
        <property type="entry name" value="YedI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30503">
        <property type="entry name" value="PTHR30503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05661">
        <property type="entry name" value="DUF808"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016660">
        <property type="entry name" value="YedI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="227"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="268"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="294" mass="31812" checksum="668AC60C884BB446" modified="2019-11-13" version="1">MASGFFALFDDIGALMDDVAAMSKITTKKTAGILGDDLAVNAEKASGFVSSREIPVLWAITKGSFLNKLIILPIAFLLSAFLPTGVTVILILGGVYLAYEGAEKIYEYFVPHHPKGEETSRLEQAELPKEEILAIEEDKIKSAILTDFILSVEIVIIALGTVVGRELLFQIIVVSIVAIIATVGVYGIVALIVRMDDLGYKLMKLNQDKKGFFYSIGNFLVMALPKIVKSLSVIGTIALLLVSGGIFVHNLEFMHHFLESIPSFIRDFIVGLAVGAVALVLMMGAKKVYGMVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD98</accession>
    <name>A0A5C6ZD98_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lipocalin family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_18045</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000029">
        <property type="protein sequence ID" value="TXD87130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024311">
        <property type="entry name" value="Lipocalin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13648">
        <property type="entry name" value="Lipocalin_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022767307" evidence="1">
        <location>
            <begin position="22"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="domain" description="Lipocalin-like" evidence="2">
        <location>
            <begin position="45"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="690" mass="77876" checksum="EAD967500098F6FC" modified="2019-11-13" version="1">MKAKVYLLLLALCCFSLSCDNDDDAPNSESNFYSGALTSASAADLTGVWAIFNVGFQGNIAEVPVVYEACGRDFLVFSENGIYTEYLYQHSGCEYHLNSLNWALNNGIINLSNQFGQSDELVITRLNANELVFKSLFDVDEDGDLDIVSLYLKPYTPNEIDMVSPTFTDHPDAAFDQLLSFTWQSYQGFNDFERYEIYRSAGDNCSISNAELIASISDVNATEFTDLSPPTEDYLCYHLKVYTNLGLLGQSYAYTINTENLNPQPVTLNTPEVLNYSIQFNWQASADPYFSHYELAFSNYDGGTASGQQVYSVAIINDRELTTFLDENPPYLEHPYYVLYVHNIFGNRSSFYNSQVTTYHEVAFKRPEIINFQKVESYAIDTENTIAYFYGRESGAGNTMNIHRFNYSTNQTEAISNLAPQYATSVPIKYIDSGYGPEIVVEQASDLAVYNATTLQYKYTLETSVPGVDDFLYSELGYWIFVNNDNIYTLTRDNANLDLVDTKPHFPNHQGSYNYQGFALNNNKLLVGYNNEDTSYLYAVATNGLMSQEQIVPIPILDNWEHESQYNAAGNYLINFSENRLYSTNTFALLQSFESPYFPSGTSQDGTLIFGSNNDPDWQITPESIHAKEAVIYNRMTQQASTISTIGYPHIIFENAFGELVSISSGLKKDDIRQNINNKADIFLEIIQLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDA9</accession>
    <name>A0A5C6ZDA9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_15455</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="97" mass="11103" checksum="001C1851C923ED71" modified="2019-11-13" version="1">MRLKDLKITNGRKIAVIEYDLQEYVSGDFGNGMLSMFTKDSNDKKTVMKMSHKATAEFDLEKGYWILYDGIMTVETNFSLMGMGGSKRTEFKLTPEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDG9</accession>
    <name>A0A5C6ZDG9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Chaperone protein DnaJ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">dnaJ</name>
        <name evidence="9" type="ORF">ESY86_17525</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 2 Zn(2+) ions per monomer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="6">The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the DnaJ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000027">
        <property type="protein sequence ID" value="TXD87235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031072">
        <property type="term" value="F:heat shock protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10719">
        <property type="entry name" value="DnaJ_zf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01152">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012724">
        <property type="entry name" value="DnaJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001305">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036410">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00684">
        <property type="entry name" value="DnaJ_CXXCXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="SSF46565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="SSF49493"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57938">
        <property type="entry name" value="SSF57938"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0346">Stress response</keyword>
    <keyword evidence="5 6" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="J" evidence="8">
        <location>
            <begin position="5"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="356"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD87235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="378" mass="40546" checksum="91A9E9BF8EFF55DC" modified="2019-11-13" version="1">MAKRDYYEVLGLQKNATAAEIKKAYRKMAIKFHPDKNPDDHEAETKFKEAAEAYEVLSNADKKARYDQFGHQAFDGAGGFNGGGMNMDDIFSQFGDIFGGGFGGGGGGGGFSGFGGGFGGGQRRVKGSNLRIRVTLTLEEIANGVEKNIKVKRKVQAPGTTYKTCQTCNGAGQVTRVTNTILGRMQTASACPTCGGAGQSIDSKSSDADAQGLIVNEETVSVKIPAGVVDTMQLKVTGKGNEAPGNGIPGDLLVVIEEQEHVSLKREGDNLHYDMYISLPDAVLGTSKEIDTVTGKVRIKVEPGVQSGKILRLRGKGIPSINGYGSGDLLVHVNVWTPKTLNKDQKAFFEAMKDDEHFEPKPESSDKSFFEKVKDMFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDY7</accession>
    <name>A0A5C6ZDY7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_15590</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="184" mass="20444" checksum="2BA55D489767DBCE" modified="2019-11-13" version="1">MMKNTINLVSFIIAASLITISCSNDDKPEDIAQQQSTYINYSVAGNQVNDTFNITVEGISNPNITAVANVFPESDSPTLKKALIVFLNSGMLGVTMSIPARTGLVEILDDHPHFDMSFVFFDEQVELQANSISVEVQEIERNDIFITHIKGNFEGIAVYKHIVNGDEVEEPHIVDGEFEYYVPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE08</accession>
    <name>A0A5C6ZE08_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_13220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="188"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="232" mass="26856" checksum="51C7D72CF7BE130C" modified="2019-11-13" version="1">MVTVISIVVTFLAYYFNISFNVDLTLLSIAIIFPLVFTIRGSFKRREKALEHLSAFRSNLKTVQAFLMSKNGLTEQEKIESVDILIEINESVLQHLGKSEYSLKDLDTITDKVFQFTLDKDATMAKGSRDKVFRFMRDVHRSIENLHSIHSHRTPISLKAYCKIFVYVFPFMYAPTIIYAIGSESLSWVAYTIVILTEFILISLYNIQNHLEYPFDNIGTDDINLDNFRITR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE28</accession>
    <name>A0A5C6ZE28_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_15425</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="137" mass="16026" checksum="C90CFFBA3B95272A" modified="2019-11-13" version="1">MPNFDQITMLKRVLETSFIKESIYSFLPTEKPYSDLLTINNDNEFVSLSNANAFIIPILEADENTIGKIKEKLNHIFNREKFVVSFQKSEYESEFENMVYIEINDLIKHAEKNGACKRNLFSLSLKELIFKDKTYAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE82</accession>
    <name>A0A5C6ZE82_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF2795 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_16980</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000024">
        <property type="protein sequence ID" value="TXD87472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_010177336.1">
        <property type="nucleotide sequence ID" value="NZ_VORO01000024.1"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021527">
        <property type="entry name" value="DUF2795"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11387">
        <property type="entry name" value="DUF2795"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="73" mass="8573" checksum="A28BE332F169EF9C" modified="2019-11-13" version="1">MYWTLELASYLSDAPWPATKDELIDYAIRTGAPLEVVENLQAIEDEGDSYDSIEEIWSDYPTDEDYLWNEDEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEB4</accession>
    <name>A0A5C6ZEB4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_18160</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000030">
        <property type="protein sequence ID" value="TXD87057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045973">
        <property type="entry name" value="DUF5929"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007421">
        <property type="entry name" value="Schlafen_AlbA_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038461">
        <property type="entry name" value="Schlafen_AlbA_2_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04326">
        <property type="entry name" value="AlbA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19351">
        <property type="entry name" value="DUF5929"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AlbA_2" evidence="1">
        <location>
            <begin position="17"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5929" evidence="2">
        <location>
            <begin position="158"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="377" mass="44045" checksum="832B8076901B1D12" modified="2019-11-13" version="1">MINKRLLIKNLLAHNDENSFYDKKRQIDIGLKEGKAKFLKHICALSNSNPKNNSYIVIGVEDSDNIILGVDFFDDSKIQNLINAYFSNPPIVMYENIPFPHLPDDKVVGLVTIRPMDELTSLRKNIWKYYGGSVFFRDGSMSMPKVFDVLIKDVNSGTVQAIEAHSQNNVEYTLDGVFDFMKKRKDYNPQYKVFKEYFVVCWSGEKKIVNAEVLFSRVDIELINEQVRLFYSTLDEVDISYDDNSFKIVEYVNLGLQKAYTYYELEETIIHFEDNMHYSIETKLLFQPPQFDKKVLHHIYNANNAILKKLQNGSSLNPNELEDLKNLPASYLICYLNLFHEALEKLHEAKPFLKLNYPEIYESYQDALRILRKVKYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEI3</accession>
    <name>A0A5C6ZEI3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Acyl-CoA dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_14055</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006089">
        <property type="entry name" value="Acyl-CoA_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00073">
        <property type="entry name" value="ACYL_COA_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="8">
        <location>
            <begin position="19"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="135"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="238"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD88218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="392" mass="43496" checksum="96A9EF8DE33D269B" modified="2019-11-13" version="1">MKPDLFEAPDYYNLDDLFTEEHKLVRNAARDWVKRDVSPIIEEYAQKAEFPKQIIKGLAEIGAFGPYIPEEYGGAGLDQISYGLIMQEIERGDSGVRSTASVQSSLVMYPIWKYGDEAQRKKYLPKLASGEWMGSFGLTEPDHGSDPGGMTTNFKDMGDHYLLNGAKMWISNSPFCDVAVVWAKNEEGRIHGIIVERGMEGFSTPETHNKWSLRASATGELIFQDVKVPKENLLPNKSGLGAPLGCLDSARFGIAWGAIGAAMDCYDTALRYSKERKQFGKPIGQFQLQQKKLAEMITEITKAQLLAYRLGQLKNEGKATSAQISMAKRNNVDMALTVARDARQMLGGMGITGEYSIMRHMMNLESVVTYEGTHDIHLLITGLDITGLSAFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEQ4</accession>
    <name>A0A5C6ZEQ4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_13360</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD88292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="233" mass="26017" checksum="03BBB49595A78772" modified="2019-11-13" version="1">MITIIDLEKYYATEEVRTIALNKLSFKVREGEFVAIMGPSGCGKSTLLNILGLLDDPDGGSFIFNDIEVAGFNERKRAELRKHNIGFVFQSFNLIDELTVFENVELPLIYTGVKAAERKERVDAVLEKMGIMHRRKHFPQQLSGGQQQRVAVARAVVNNPKLILADEPTGNLDSSNGNEVMDLLTELNEAGTTIIMVTHSEHDAKYSHRIIRMLDGQKVTENILADYKSSVAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZER7</accession>
    <name>A0A5C6ZER7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sulfatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_16090</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="PTM">
        <text evidence="4">The conversion to 3-oxoalanine (also known as C-formylglycine, FGly), of a serine or cysteine residue in prokaryotes and of a cysteine residue in eukaryotes, is critical for catalytic activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000021">
        <property type="protein sequence ID" value="TXD87689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008484">
        <property type="term" value="F:sulfuric ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.720.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032506">
        <property type="entry name" value="DUF4976"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024607">
        <property type="entry name" value="Sulfatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000917">
        <property type="entry name" value="Sulfatase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16347">
        <property type="entry name" value="DUF4976"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00884">
        <property type="entry name" value="Sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00523">
        <property type="entry name" value="SULFATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00149">
        <property type="entry name" value="SULFATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Sulfatase" evidence="5">
        <location>
            <begin position="33"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4976" evidence="6">
        <location>
            <begin position="419"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="modified residue" description="3-oxoalanine (Cys)" evidence="4">
        <location>
            <position position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR600917-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD87689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="555" mass="63991" checksum="0D7E7216EE771178" modified="2019-11-13" version="1">MKNLLSILWIAIVCYSCNEAKTPDVAEAPKKRPNIIFIMADDHATQAISAYGHPISDLAPTPNIDRIANEGAIFKNNFNTNSICGPSRAVILTGKHSHINGFRMNGERFDGSQQTFPKLLQNAGYSTAVIGKWHLHGYPEGFDYWNILLDQGNYYNPDFISLKDGQAVADTTRVPGYATDLITEDAINFLDKAKDANKPFMLMLQHKAPHRNWMPALRHLHTYDAVEFPVPDTYFTDHEGSTASKEQSMTIYTDMYEGHDLKMTKKKGSPELAHNPWKTNFDRMTQAQRAEWDKAYQPKNDAFHEMNLKGKDLALWKLQRYLQDYMATIASVDEGVGTILDYLEANGLAENTIVVYTTDQGFYLGEKGWFDKRFMYEESLAMPMLMKYPNLITPGTEITALTQNLDFAETFLDMAGVPIPEDMQGKSMLPLFTKDMEDADFRDAIYYHYYDFPAFHMVKKMYGVRTKRYKLIHVYDDIDEWELYDLEKDPSEVHNLINDDDYNDIAEKLHKRLDALQKQYKVTDKEFEKVSPEAIKRNYMNFEKLRGKALKSYKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEW6</accession>
    <name>A0A5C6ZEW6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4412 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15605</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025524">
        <property type="entry name" value="DUF4412"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14371">
        <property type="entry name" value="DUF4412"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4412" evidence="1">
        <location>
            <begin position="90"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="283" mass="32016" checksum="93A07D2067E4AE11" modified="2019-11-13" version="1">MKNGLKTYNVEQLKSKKMKTKHIITVIICLLIGGTADAQIFKEIMKVVGKKEKKTTEKTDEEKAEMNKKAMSIFGGSLEGLPETYQFSYVVDMQITSKKDETTMQYFVEPDATYFGNALPEDKTNSIIVYDMENQAMVTFMDNDGNKMAMKMRIPISDKKMQALLKKESDATKTKIENGTITPLPDKKILGYTCKGYQIIQKDGVSKIWFTNEAPVSFVGMFASADKMPKNLSGDMIPFGPKSMMLEMEYTANKRKRDNMRMVCTGIEEKSFAIALKDYKTGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF95</accession>
    <name>A0A5C6ZF95_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="63" mass="7582" checksum="666FB334F2DD50A9" modified="2019-11-13" version="1">MFEFDQYLGFLAFLAILTLGFWLMIFLITFVVPYWIGGSLLERFQEYKAEKKAKREKEEQLSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFA0</accession>
    <name>A0A5C6ZFA0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010438">
        <property type="entry name" value="Lambda_Bor"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06291">
        <property type="entry name" value="Lambda_Bor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022906095" evidence="1">
        <location>
            <begin position="22"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="93" mass="10080" checksum="EAC8BA68EBA0A09F" modified="2019-11-13" version="1">MKMMTIVFASSMLLTSCYSYTSVVGEGAQGNNQVTEWNHYVIYGLAPVGVSDSKQMADGAENYTVYTRQSFVNGLVTAITFGIYSPSVTTVTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFF5</accession>
    <name>A0A5C6ZFF5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022733091" evidence="1">
        <location>
            <begin position="19"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="282" mass="31112" checksum="0C33BCE5B2922D69" modified="2019-11-13" version="1">MKLSNLLPVLMLALFTMACSSSDDQAPLVINEVEGLIKIQEISNSTHTIELFNKSGLFETGFNDISLRLKDKVTDAYIEEASISWMPMMQMPSMQHSCPKSAISKVAGKATLYQGNIIYQMTNTDGSGWSLDLNYTLDGVDYMASDTISVFQSESQNVSSFTGSDDMRYVLALIAPEKPIIGINPMEVGLYKMESMMAFPAVPDYTIKLDPRMPGMGNHSSPNNTDLIFQLADASYQGNLSLTMTGYWVLNLKLINAAGELLKGKDVTVENTQSSLYLELEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFG6</accession>
    <name>A0A5C6ZFG6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_13560</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="160" mass="18461" checksum="62C1B9BA380EAEA8" modified="2019-11-13" version="1">MKFIAISISRYVEKHLINNPSENETDLRKRLDSAIDAYQNGVKCSCGNDIWVVGSASLGNNCFTCITGESQPNEDYEIDLAVKKRENTQGRKNIAEMDKTQIKGYFDDEGYEIRPELIKRPSLCLICVNNNNPKEQILCNMTRYDQKDENEFKCFEFIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFI6</accession>
    <name>A0A5C6ZFI6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Nucleotide-diphospho-sugar transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_16890</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000024">
        <property type="protein sequence ID" value="TXD87455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="316" mass="37645" checksum="DA7C0CD816E8D6BE" modified="2019-11-13" version="1">MFKTPVLYIVFNRPDHVRKSFMRIKEVAPKKLYVAADGPRSDHEHDIQNCLKVRQYIQDNINWECEVVYLFREPNLGCGKAVSGAIDWFFENEHEGIIIEDDCIADISFFRFCEELLDRFRDDAEIFQITGSNWQKGKKRGRADYYFSHMSSVWGWATWKDRWDSYEYTIDVESDDYLKMKDNLKEIACNKSEENYHLNCFERTAIGKIDTWDYQWRYLMLLNKGINVVPNYNLVSNAGFGKEGTHTFDSRHWRANLESQTVNFPLKHPKRIEVNKKADAFLAKNIWLLNSKIKKRNLTKVLKRLKVIKYRFYGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFJ4</accession>
    <name>A0A5C6ZFJ4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Phosphoglucosamine mutase</fullName>
            <ecNumber evidence="11">5.4.2.10</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">glmM</name>
        <name evidence="11" type="ORF">ESY86_11470</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.10" evidence="11"/>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008966">
        <property type="term" value="F:phosphoglucosamine mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016066">
        <property type="entry name" value="A-D-PHexomutase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005841">
        <property type="entry name" value="Alpha-D-phosphohexomutase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024086">
        <property type="entry name" value="GlmM_arc-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00509">
        <property type="entry name" value="PGMPMM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="SSF53738"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="SSF55957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03990">
        <property type="entry name" value="Arch_GlmM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00710">
        <property type="entry name" value="PGM_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM_PMM_I" evidence="8">
        <location>
            <begin position="8"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_II" evidence="9">
        <location>
            <begin position="172"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_III" evidence="10">
        <location>
            <begin position="270"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_IV" evidence="7">
        <location>
            <begin position="395"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD88848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="462" mass="50014" checksum="92309F1C961B9785" modified="2019-11-13" version="1">MTLIKSISGIRGTIGGKVGDNLTPIDAVKFAAAYGTWIKQQRSKENYRVVVGRDARISGAMMQNLVMNTLVGLGIDVIDLGLSTTPTVEIAVPMEQSDGGIILTASHNPKQWNALKLLDAKGEFLNAEEGAKILNIAESDAMTFAEVDNLGEIHVNDAYIDIHIDEVLDLELVNVEAIKKADFKVVVDGVNSTGGIAIPLLLERLGVEAVKLYCEPNGHFPHNPEPLKEHLTDLSKEVVKAHADFGIAVDPDVDRLAFIDETGEMFGEEYTLVACADYVLSKTPGNTVSNMSSTRALSDITKKHGGTYKASAVGEVNVVNMMKQNNAVIGGEGNGGIIYPELHYGRDALVGVALFLSLLAEKKMSVSALRASYPDYYMSKKKIELTADLDVDALLTAMEAKYAEEKLTTIDGVKIDFENSWVHLRKSNTEPIIRIYTEAASQAEAHALADRVISEIKEIAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFJ8</accession>
    <name>A0A5C6ZFJ8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fasciclin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_15135</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD88000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02469">
        <property type="entry name" value="Fasciclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00554">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="SSF82153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50213">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022680443" evidence="1">
        <location>
            <begin position="23"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="2">
        <location>
            <begin position="23"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="170" mass="17992" checksum="AAED7B69AC1F1203" modified="2019-11-13" version="1">MKKLILILTISMSVALSNTVTAQETIVDVAVGNEDFSTLVTALKAADLVGALQGDGPFTVFAPTNDAFAKIDSKTLNSLLEEKNQKALANILTYHVVAGKLTAKDVTAALKNGNGTVELEALNGEEITVMQKDGKIWLKDSKGNYSEITATDVMGSNGVIHVIDTVVMPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFY1</accession>
    <name>A0A5C6ZFY1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD family phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_10750</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="224" mass="25077" checksum="939772C88F67F51E" modified="2019-11-13" version="1">MKTQRITRPNALLFDFDGVVVNSFQIHGWSWRAAFESLFQKELPVLNRDAYAGKAPRLIAALFAETQGAPDRANELLMKKQAFLEEAVEPPLLLPGVNAIQQFAKQQGIPYGIASNANRNYVGKSIAQLEIDFEVYFGFEDYTYPKPHPEAYITLAKHLGIKPSEFQNSWVFEDSLVGISAAREAGMFPVGILTQYTAKQLQEAGALISFPTLMEAYQKLKTEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFZ0</accession>
    <name>A0A5C6ZFZ0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_14600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="233" mass="27128" checksum="415C653E065F715C" modified="2019-11-13" version="1">MKNQVFQAILFILFSFVGYSQNDDTDSFQQIMDGSPYSVMTKSINSKEVKGSPYLYDIFFPAKIAGLQEKIFNVRYNAYFDEFEIKDAEDQINLVNKDLQQLTITFSNDQTVFISSSYLDQNNQITRGYFVVASPENQKNQLLIKKSKRYSESKPARSSYEKSKPAEFEENKDTYYLRLSDGVAKEIPRNKKDLANMYPKHSKAILDFIKKNRINTTEREDLVKLVKYLNSLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG08</accession>
    <name>A0A5C6ZG08_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="104" mass="11570" checksum="6D45EFB572676ABF" modified="2019-11-13" version="1">MNPLRISVKPQRISVEQPSISAKPLRISVKPQRISVKQPSISMNTLRISVKQPSISVNPQRISVEQPSISVNPLRISVKPQRISAKQPSISVKQPSTTIKQHFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG25</accession>
    <name>A0A5C6ZG25_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Nucleotidyltransferase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_09690</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039498">
        <property type="entry name" value="NTP_transf_5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14907">
        <property type="entry name" value="NTP_transf_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="357" mass="41765" checksum="7A425F278D68049A" modified="2019-11-13" version="1">MFVLQNHNLTTNATSNKDTLQLIVDILRFDAHESQLKLRLTQAKDTDWDQLVSIASGHLVLTAVYCRLEQKQLLEALPKDLITYLRELTNINRARNQGLISEAQLVANILERNGIEYAFIKGMGLLLSNCYQDLGERMIGDFDILVPEKDIDFAFQLLIDNGYDQLIGFNYENTGFRHLDRQVNPERLAAIELHRDVLISGHRELLDLSAIIQDKRFENGTFVASKKHLGQINILTTQLNDDSFYFNRLNFKNVYDSLVLWKNKDFSDVKEFKSNPYISRYLSLLQVWNLKTGFHENAWLDRFHTQFYQFKINRKPLEVAEYRVKVIILDVSRRLKLFITNTSYRKHILKNKIFSKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG85</accession>
    <name>A0A5C6ZG85_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">AI-2E family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_14060</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002549">
        <property type="entry name" value="AI-2E-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21716">
        <property type="entry name" value="PTHR21716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01594">
        <property type="entry name" value="AI-2E_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="34"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="137"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="204"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="232"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="263"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="297"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD88219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="343" mass="38201" checksum="34A42844A36EA4FB" modified="2019-11-13" version="1">MNTEKIDISAVNLIKMLFIIGGLLALFYYGKTLIMPLLVAAIIAILLDIPVKKLKSLGLPNWLSITLSVLFMIVIFSLLFWLLSSQINNMAQDWSTIRDKATEKLNSLSQWANKSLNWDYQDYIENNKKLVKNAEDFAGAFLSSLMTLLSQSLIIFVYIILFLMQKQQFVNFFKKLFSDQKAISSLLKTAAKITKSYFVGKGKIMLFLFGIYYLGFMLGSVPYALFLALFAALFSIVPFVGNIIGGGVAVILSYLYAGSTPALIVIGVVSAAQLVENYVLTPWIIGDEINLNPFMTIFGIILFSALWGVVGAIIALPLIGVLKVIFDHTKNMEAYAYLLKKTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGI4</accession>
    <name>A0A5C6ZGI4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycoside hydrolase family 19 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_13605</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004568">
        <property type="term" value="F:chitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016998">
        <property type="term" value="P:cell wall macromolecule catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006032">
        <property type="term" value="P:chitin catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000726">
        <property type="entry name" value="Glyco_hydro_19_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00182">
        <property type="entry name" value="Glyco_hydro_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_19_cat" evidence="1">
        <location>
            <begin position="86"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="212" mass="24179" checksum="7B3DB50AB479B412" modified="2019-11-13" version="1">MVSTTQMKTIIPKLNWEKAEPYIPYMTSVLPNFGIDTPLRKAHFLAQLAHESGGLKYATENLNYSAQALRSVFGKYFKTIEIAEAYARKPEKIANRVYADRMNNGNEASGDGWKYRGRGLIQLTGKDNYQNFAKDHGVDCVNNPDLILDPEIALNAACWYWTKRNINRYADADDIHMVTKKVNGGNNGILDRQHWLASFKNLYKVLETNTNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGQ4</accession>
    <name>A0A5C6ZGQ4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Trk system potassium uptake protein TrkA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">trkA</name>
        <name evidence="9" type="ORF">ESY86_10035</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015079">
        <property type="term" value="F:potassium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006036">
        <property type="entry name" value="K_uptake_TrkA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02080">
        <property type="entry name" value="TrkA_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02254">
        <property type="entry name" value="TrkA_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00335">
        <property type="entry name" value="KUPTAKETRKA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51201">
        <property type="entry name" value="RCK_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0630">Potassium</keyword>
    <keyword evidence="4" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="RCK N-terminal" evidence="7">
        <location>
            <begin position="2"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="8">
        <location>
            <begin position="141"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="RCK N-terminal" evidence="7">
        <location>
            <begin position="234"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="8">
        <location>
            <begin position="369"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD89100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="449" mass="49812" checksum="6BCAC53093326109" modified="2019-11-13" version="1">MKIIIAGAGEVGFHLAKLLSYESQEITLIDIDREQLSYARDHLDIKVIKGDVTSIKILKEAKINTSELFIAVTSSETTNITACVLAKQLGAKRTIARISNEEFINDKEEVGFSKFGIDELISPESLAAAEIELLLNQYGFNDTYEFEKGVLSMLSLRLSRTASFVGKTVMEAAAVFPELHFVPIAIQRFGTQYTIIPRGDTEFKEGDKVVFVTSEGGDEELFELSGRVKTEVKNVMILGASKIGFQTAKDLCQSKFKVKLIENNKEIAFESADELPNALVIHGDGRNVELLEEENISDMDAFISVTGNSETNIMSCLVAKSKGVKKTIALVENMDYYQLSQSIGIDTLINKKLLAANNIFRYIRKGEVVAMTKLNNMNAELLEFQVNSKSKITKKVIRDLDFPRSAIIGGVIRNDVGIIPLGDFQIEVGDKVVVCCLPRSISKIEKYFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGU1</accession>
    <name>A0A5C6ZGU1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Cytochrome-c peroxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ESY86_15380</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
        <text evidence="6">Binds 2 heme groups.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Periplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="6">Binds 2 heme groups per subunit.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009056">
        <property type="entry name" value="Cyt_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004852">
        <property type="entry name" value="Di-haem_cyt_c_peroxidsae"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026259">
        <property type="entry name" value="MauG/Cytc_peroxidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03150">
        <property type="entry name" value="CCP_MauG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000294">
        <property type="entry name" value="Cytochrome-c_peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46626">
        <property type="entry name" value="SSF46626"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51007">
        <property type="entry name" value="CYTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 6 8" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7 8" id="KW-0408">Iron</keyword>
    <keyword evidence="3 7 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0574">Periplasm</keyword>
    <keyword evidence="10" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cytochrome c" evidence="9">
        <location>
            <begin position="236"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent" evidence="6">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="6">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>1</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <feature type="binding site" description="covalent" evidence="6">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="covalent" evidence="6">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="7">
        <location>
            <position position="255"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
            <label>2</label>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000294-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000294-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD87851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="387" mass="43972" checksum="B056E380FACB9FE2" modified="2019-11-13" version="1">MNVFTLLKYGLFVFSCCFLLNCKVDAKSEYVSISISNLRAQYAQADTKKWPEPELDSLVDRSKFEDLGVLPEVEYPNDNPFSEEKKQLGKLLFFDARLSESKQIACANCHNPELAWTDNITRSLGHERQENTRNAMSIMNVAFAKRLFWDGRAESLEHQASFPISDPVEMNTHSTVTLENIANIDGYKPLFTEAFGDAQVTLDRVLKAIATFERSLVSRNSKFDKFVSGKAEAFTDQEVLGLHLFRTKARCINCHNTPYFSDNLFHNDGQALFGTNDEDFGLYNHTNKLEDLGKFRTPSLREVAMTGPWMHHGHFPSLLDVVEYYNLGNPAPIQKKYLGTTRDSLIPTTSPMLEKLELNKTEVEAIIAFLETLSTKTQRVNLVNMPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGZ2</accession>
    <name>A0A5C6ZGZ2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NlpC/P60 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_09310</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C40 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000064">
        <property type="entry name" value="NLP_P60_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00877">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51935">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022716033" evidence="2">
        <location>
            <begin position="22"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="NlpC/P60" evidence="3">
        <location>
            <begin position="46"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="173" mass="19538" checksum="FC7D4AC0F21182A0" modified="2019-11-13" version="1">MRLFAFILLLCFCLSSCKSKSNVVTKKHRSTKTVANNRTSPSADTPKNIANIIDYAKTFEGTRYKYGGTTKRGMDCSGLIYTTFQKENIYMPRTTDGLSKEGDWVDVNDVKEGDLLFFATSKNSRSVNHVGIVTATRPGFVEFIHSSSSRGVMRSTLSERYWYLAYVQARRVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH09</accession>
    <name>A0A5C6ZH09_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Homogentisate 1,2-dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_08590</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the homogentisate dioxygenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004411">
        <property type="term" value="F:homogentisate 1,2-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006559">
        <property type="term" value="P:L-phenylalanine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006570">
        <property type="term" value="P:tyrosine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005708">
        <property type="entry name" value="Homogentis_dOase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11056">
        <property type="entry name" value="PTHR11056"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04209">
        <property type="entry name" value="HgmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="388" mass="44955" checksum="079D5884814A5C96" modified="2019-11-13" version="1">MPFYHKLGKIPPKRHTQFRKEDGSLYSEQLFGTIGFDGMSTNSYHEQRPTQVKAIRKQYSVAPKIAKANHIQSYRLRGFQVKPEADYLQSRKTILTNSDCSIILAAPQQSTKDYFYKNSDADELLFIHKGTGKLRTHLGNLDFKYGDYLVIPRGVIYKIDFDTEDNRLFIVESRRPIYTPKRYRNWFGQLLEHSPYCERDLRRPYELETNNESGDFLMKVKKQGDIFEMIYASHPFDVVGYDGYNYPYAFSIHDFEPITGRIHQPPPVHQTFETDAFVVCSFVPRLYDYHPDSIPAPYNHSNIDSDEVLYYVDGDFMSRNDIEVGHISLHPAGIPHGPHPGAAERSIGKTKTEELAVMVDTFKPLQLTEEAMKIADEDYFKSWLPHEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH35</accession>
    <name>A0A5C6ZH35_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Adenylosuccinate synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD89011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="59" mass="6836" checksum="D7AA91613946EEC7" modified="2019-11-13" version="1">MGYSLLLQIPTDVPKPGDSGTVDLSEPFDLIVFIILPIVFVILYFVWKRNKKRDRDKNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH91</accession>
    <name>A0A5C6ZH91_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">Orotate phosphoribosyltransferase</fullName>
            <shortName evidence="4">OPRT</shortName>
            <shortName evidence="4">OPRTase</shortName>
            <ecNumber evidence="2 4">2.4.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">pyrE</name>
        <name evidence="6" type="ORF">ESY86_15120</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>diphosphate + orotidine 5'-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + orotate</text>
            <dbReference type="Rhea" id="RHEA:10380"/>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57538"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="EC" id="2.4.2.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="1 4">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.10" evidence="2 4"/>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00119"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004588">
        <property type="term" value="F:orotate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01208">
        <property type="entry name" value="PyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023031">
        <property type="entry name" value="OPRT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004467">
        <property type="entry name" value="Or_phspho_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00336">
        <property type="entry name" value="pyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 4" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="5">
        <location>
            <begin position="58"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="5-phosphoribose 1-diphosphate binding" evidence="4">
        <location>
            <begin position="126"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>orotate</name>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD87999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="214" mass="24034" checksum="1787F4BB150ACD5E" modified="2019-11-13" version="1">MIFDKETAKKTAELLLQVNAIKLQPNDPFTWASGWKSPIYCDNRIVLSYPPIRNYIRTTMARQIEAHYGKVDVIAGVATGAIGIGILVAEYLGLPFVYVRPEPKSHGRQNQIEGFLESGQHVVVVEDLISTGKSSLNAVRALKEANVHVKGMLAIFSYGFEVAEKNFEEAHVELRSLSNYDNLLEQAQETLYINKKEQQILSLWNANPSEWTAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHC0</accession>
    <name>A0A5C6ZHC0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HAMP domain-containing histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_13345</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="230"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="447" mass="50731" checksum="3E965BC35EF76175" modified="2019-11-13" version="1">MTYKSYVFSLTIRVLGLLLALILLAFGIAWVKTYVIIGGGILSVIAVYHLYRFMVKRFVEVDDFFESIKYRDFSRWFVETKGPQDIRELHKGFNLVNKTIKAIDSERQAQFVYLQKILEMVNIGLIAYNVETGEVLWTNDSFLKTLDFPAFKNISFIEKRAAKIYDELFETYHSNTTSVTLELRQESLKVLISDTVFEMESHSFKLIVLQNIEDTLNRNESEAWKKLLSVMTHEIMNSIAPITSLAETLQKNIQQSIEHPKTTSLELEDVNAGLNSIKKRSAGLMKFAKTYRSLNKITHVNKTKIKVSELFDNISELMKPSLEDREVQLIFKLDDPNLLFEIDAYLIEQVLINLILNAFDATESVVKPQITVSAAIGYKGAAQIKVSDNGKGIPAEIMDSIFVPFFSTKKTGSGIGLSLCKQIMLLHGGKIQLQSIEHEGTVVSLLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHU1</accession>
    <name>A0A5C6ZHU1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_08265</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="92" mass="10911" checksum="DE5AEF4F716440D0" modified="2019-11-13" version="1">MLLIIIKKIKDLKNLFCKLFQHEIVVKTDVTKIVKEYECIHCKKQFTTSDKGKLIPLTTKRKETNKVLKSLYQRRKKIKKLIPNGRLKRSSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI32</accession>
    <name>A0A5C6ZI32_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glucose-6-phosphate isomerase</fullName>
            <shortName evidence="7">GPI</shortName>
            <ecNumber evidence="7">5.3.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Phosphoglucose isomerase</fullName>
            <shortName evidence="7">PGI</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Phosphohexose isomerase</fullName>
            <shortName evidence="7">PHI</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pgi</name>
        <name evidence="9" type="ORF">ESY86_08620</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7 8">
            <text>alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:11816"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="EC" id="5.3.1.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 7 8">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 8">Belongs to the GPI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.9" evidence="7"/>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00181"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004347">
        <property type="term" value="F:glucose-6-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05015">
        <property type="entry name" value="SIS_PGI_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05016">
        <property type="entry name" value="SIS_PGI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00473">
        <property type="entry name" value="G6P_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001672">
        <property type="entry name" value="G6P_Isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023096">
        <property type="entry name" value="G6P_Isomerase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018189">
        <property type="entry name" value="Phosphoglucose_isomerase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035476">
        <property type="entry name" value="SIS_PGI_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035482">
        <property type="entry name" value="SIS_PGI_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11469">
        <property type="entry name" value="PTHR11469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00342">
        <property type="entry name" value="PGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00662">
        <property type="entry name" value="G6PISOMERASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00765">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00174">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51463">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 7 8" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="4 7 8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="5 7 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="355"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="386"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD89436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="548" mass="61999" checksum="F70D57A324318446" modified="2019-11-13" version="1">MALAAINPTTTKAWKKLQAHFDTIKNQPAKQFFAEAPHRADDMRIVWEDFYVDYSKHRLTSETMALLLELAEEVKLKDAMSQYFGGEVINQTEGREVLHTALRNPKSAEVMVDGENVMPEIYEVKNKIKGFTEAVVGGKLKGYTSKTFTDVVNIGIGGSDLGPAMVVESLGYYKNHLKTHFVSNVDGDHVNEVIKTLNPETTLFVIVSKTFTTQETLSNANTIRAWFLKSAPQHAVSKHFVAVSTNIEKVKAFGIDEKNIFPMWNWVGGRFSLWSAVGLTISLATGFDNFDKLLTGAHKMDQHFRTEDFDKNIPVITALLSVWYNNFFKAESEAVIPYSQYLNQFATYLQQGIMESNGKSVDRNGDKINYQTGTIIWGEPGTNAQHAFFQLMHQGSKLIPAEFIGFTKSLYGNQDHHDKLMSNFFAQTEALWNGKSKDTVIEELKAQGLSEEKIKELSPYKVFEGNKPTTTFLIDKLTPESLGKLIAMYEHKIFVQGIIWNIFSYDQFGVELGKELANTILKEIEDKNVINNHDISTQNLINRYKTHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI49</accession>
    <name>A0A5C6ZI49_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_06590</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="83" mass="9747" checksum="4F582ABD7A15FF34" modified="2019-11-13" version="1">MYNAKDTIFISLYIFRKWNPAGLFRFDERWNGINGSVKLFKFFLAIGNSMRFQIGKIRNFTSILNKAINYFSGLSIKNEINLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIA1</accession>
    <name>A0A5C6ZIA1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Serine hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_07540</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001466">
        <property type="entry name" value="Beta-lactam-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00144">
        <property type="entry name" value="Beta-lactamase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-lactamase" evidence="2">
        <location>
            <begin position="90"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="383" mass="43301" checksum="03FF13842AC41B5A" modified="2019-11-13" version="1">MKFLKNLLKFLVVLIALIIAILYITDTDYLIKAVRTIYLKGHSTAYLEDYKEFDNQAIANGSPQPWPNHIDYNSVNATERLKKANKDWGTIAYVIIKNDSIWFEEYYDGFGEDSKSNSFSMAKSYVSGMLGKAIMEGHIKSLDQPVCDFLPAFCEGKAAKMTVGDLSSMSSGTDWVEAYYSPLSITTRAYFDDDLSKVINGLKVVNEPGTAYKYASGDTQMLAMVIEKATGKNLYTYLEESFWKPLGSENATLWQVDSETHDLVKAYCCIASNAKDFARFGKLYKDHGKWNGKQVLDSAFIAKSIKPRFPSSPEYGYGWWLKKHLGKDFYMMRGHLGQYVMVQPEDNVMIVRLGHSKGPGDALETFTPDIGLYIEEAYEMLNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIC1</accession>
    <name>A0A5C6ZIC1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Succinate dehydrogenase/fumarate reductase iron-sulfur subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_07190</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[3Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:21137"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004489">
        <property type="entry name" value="Succ_DH/fum_Rdtase_Fe-S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025192">
        <property type="entry name" value="Succ_DH/fum_Rdtase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13085">
        <property type="entry name" value="Fer2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13183">
        <property type="entry name" value="Fer4_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00384">
        <property type="entry name" value="dhsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="3">
        <location>
            <begin position="150"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="247" mass="26899" checksum="1442FE71C51863B2" modified="2019-11-13" version="1">MKIIFKIWRQDSPAEEGMLKTYEVDDLTEDMSILEALDHLNELLVLRDEKVIAFEYDCREGICGQCGIFINGRAHGPHDQITTCQLHLRSFNDGDTVVIEPWRAASFPVLKDLIVDRSAFDRIIESGAYISSKTGSAPEANAILIAKEVSDTAMDAAACIGCGACVATCKNSSAALFTSAKINHLNSLPQGESEAHKRVIEMTSQMEAEGFGSCTFTGACEVECPESISIVNIAEMNARIIKAKIFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIL2</accession>
    <name>A0A5C6ZIL2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07255</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="244" mass="27801" checksum="2C4D7769A7C024E7" modified="2019-11-13" version="1">MKNSNNISQELLETVERHLNKTMSKQEALDFELRLAEDPQFRTHVADIKTLLLGIGNQSLKERLDEFHEALPESQMESSNSKTKSTMLWGKFAAAILIFAAIGGFWWFSTTQNERLYAEYFTPDPGLPTTMSSSTNFEFYDAMVDYKQGNYKIAIEKWEALSIENDTLDYFLGVAYLADKNQKRAIPFLEKSTQNTAFPLLNDAYYYLGLAYLKEGNIALAKKNLSLSATEDSQLLLSELEKNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIM0</accession>
    <name>A0A5C6ZIM0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type II toxin-antitoxin system RelE/ParE family toxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_09725</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2310.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007712">
        <property type="entry name" value="RelE/ParE_toxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035093">
        <property type="entry name" value="RelE/ParE_toxin_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05016">
        <property type="entry name" value="ParE_toxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="98" mass="11411" checksum="7432095B09AD2B63" modified="2019-11-13" version="1">MANYKLSVAAREDLIRIHHYGTDKFGITQADQYFDSFFEYFEVIANSPFSFQSVDFVKAGYRRCVCGVDSIYYKINDDNIVEIMAIIGRQDLNNILKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIP8</accession>
    <name>A0A5C6ZIP8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MBL fold metallo-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_04890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050313">
        <property type="term" value="F:sulfur dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07724">
        <property type="entry name" value="POD-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044528">
        <property type="entry name" value="POD-like_MBL-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="260"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="360"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="443" mass="48821" checksum="2FC5D8A5578C8E9D" modified="2019-11-13" version="1">MKIKQFEYTPLAHYSYAIVSEGKMAVIDPERNPAQYYAYAEANNAKIVAVIETHPHADFVSSHLEIHKTTGATIYNSKKLGADYPHQSFDEGDGISLGQISLKAINTPGHSPDSITIVAEQGDETALFTGDTLFIGDVGRPDLREKAGNMKAKREDLAEMMYDSISTKFNDLPDNALVFPAHGAGSLCGKNLSDAASSTLGDERANNWAFKKQSKKEFMDTLLDGQPFIPHYFGFDVDMNKTGADNLEPAIAKVPFEAHTAAEGLIVDVRNEVAFKKGHLKGSINIQAASVTAKFETWLGAIIKPKDSFTLVLDAKENKDPILHRVAKIGYEKLLKKIITLKDENLVKTEKLDLADFKKNPDNYTIVDIRNQSEIDEGLFFENAHAHPLNELRDTAKDIPTNKPIVVHCAGGYRSAAGSSILEYKLNGVTVYDLSDDVEQFKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIR8</accession>
    <name>A0A5C6ZIR8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">T9SS type A sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_04800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022805440" evidence="1">
        <location>
            <begin position="20"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="domain" description="Por_Secre_tail" evidence="2">
        <location>
            <begin position="919"/>
            <end position="991"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="992" mass="108044" checksum="CE4F1DF9271875DA" modified="2019-11-13" version="1">MKKIYIPILAALLSVLCHAQDYKRMIAAGSFSVQEIQIAAQAHFDQVGRERGKGYKPYKRWEYQALRRMDENGMLKSPEFYVKELEDYNSYLNNANIQARTTVGTWEQLGPLSINQTSGWNPGVGRITSFAAASDNPNHIIVGANTGGVWKSLDGGGTWAVLTDNLSNLSVYALAIDPTNTNTYFWGSTGGVIFKSEDAGATWNILAQTGIGNVNKILIDPSNTNKMYCSVEFGGIYKSVDAGNTWTSINSAATNGYDVELKPGDPNVVYASGNAFFISTNGGDTFEVPNGLDVWSQNYLSGNTNWTTSAFNQNNSVVPRTGNSMAIFSIDNFSMPITQLVTPALDVSGITNPQLKFSFTNVSWAGDIDALKILYKTTASGDWIELANYTTESASWNDINLNLPNPSATYYIAFEGTSNYGRGLTIDDIMVGNDLGSIVFVDGFESATNSFGGGPKMIAVTPANPELVYVVEAVDNVFGGLHKSTNSGSSFTRLGHSGKNYFGYSSDPEDLADATFGQAPRDMDIAVHPSNSDDVHLAGINTWRSTDGGTTFNISSQWTPQGAAFENIGYCHADVDMLEFVGDQLYVLSDGGIYVAQDPTSVSSSYYTDLTTGLGIRQFYKIGVSQTNPVIVTAGSQDNGSSVLGANGIWSDWLGADGMESFVDKTLSNTLYGTVQYGALYKSIDGGNNIFSLDAPENKSGNWVTPFEQDPIQPNTIYTGYDQVYKSVNGGDTWTSVSQSFGGNLNHLKIAPTNGNFQYAARGNKLYKNTNVGTTGNWTQLNGFSGNINAIAIHPTDPNKVAIATTSNQNVFVSINGGSSWTSYKINLPNFSAQALVWQDNGKDGLYLGMNYGVFYIDQTMSEWQPFSNGLPNVMISELEINYATDKIYVGTYGRGLWASNLYDTTLNVSDFKLKNLNVYPNPSSNDINLKWDQNEEVTIRIYDTQGKIMFYDKNDNIKNGLQIDVSNFASGLYFLKVNTNKGEVTKKIMVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIU7</accession>
    <name>A0A5C6ZIU7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07805</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="191"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="230" mass="27180" checksum="0A8BD4213A627C3D" modified="2019-11-13" version="1">MRTVNPQEIAQLYQFTRAHFVEYYDLQTELVDHLANDMEVIWQKQPKLSFEQARDASFKKFGVFGFMDVVGERQKAMTKRYMTYLWQEFRQWLTLPKLAITLCLFLVFYTAFSSPFVPLFLVLVFGYHAVWSIYKSVILRKRFKSRRENTSKKWMLEEMIFKQAGGAALLLMSQLPTWYNLSGAYLSNPTLVIGISLFTTVFSIYMYVSFELLPNKAEELLNQTYPEYSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIX2</accession>
    <name>A0A5C6ZIX2_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Lipid-A-disaccharide synthase</fullName>
            <ecNumber evidence="2">2.4.1.182</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">lpxB</name>
        <name evidence="10" type="ORF">ESY86_09315</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Condensation of UDP-2,3-diacylglucosamine and 2,3-diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>a lipid X + a UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-alpha-D-glucosamine = a lipid A disaccharide + H(+) + UDP</text>
            <dbReference type="Rhea" id="RHEA:67828"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:137748"/>
            <dbReference type="ChEBI" id="CHEBI:176338"/>
            <dbReference type="ChEBI" id="CHEBI:176343"/>
            <dbReference type="EC" id="2.4.1.182"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.182" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008915">
        <property type="term" value="F:lipid-A-disaccharide synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003835">
        <property type="entry name" value="Glyco_trans_19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30372">
        <property type="entry name" value="PTHR30372"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02684">
        <property type="entry name" value="LpxB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00215">
        <property type="entry name" value="lpxB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 10" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0441">Lipid A biosynthesis</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00029342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD89236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="372" mass="42540" checksum="D610C8D585112E87" modified="2019-11-13" version="1">MKYYLIAGEASGDLHGSNLMKALQQEDVNAEFRFWGGDLMASVGGTLVTHYKERSFMGFAEVLFNLRAILGFIKFCKQDIQNYHPDVIVFIDNSGFNLRIAKWAKQRHYRTHYYISPQVWASRASRVTAIKRDIDAMHVILPFEKAFYEKYDYEVNFVGHPLIDAIANRTQIGEHAFRKKYGLNDKPIIALLPGSRKQEITKMLGVMLSVVNDFRDYQFVIAGAPSQDYEFYKPFIKENKVSYIPNKTYDLLSVSFAALVTSGTATLETALFKVPQVVCYKANAISYQIAKRIITLKYISLVNLIMDREVVTELIQSDLNSEGLKKELRKILDDEERDRLFLEYYELEKKLGGKGASAKAAKFIFDDAKSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIZ5</accession>
    <name>A0A5C6ZIZ5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Biopolymer transporter ExbD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_11695</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ExbD/TolR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003400">
        <property type="entry name" value="ExbD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30558">
        <property type="entry name" value="PTHR30558"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02472">
        <property type="entry name" value="ExbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD88628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="186" mass="20877" checksum="AB1FB31F8DD11902" modified="2019-11-13" version="1">MKNSRRYSVEVNAGSMTDIAFLLLIFFLVTAVIPKDKGISRTLPSDCPPGVHCNADIAQRNLLQIYINSEDQLMVDNQLVFIAELKALAVDFLDNNGDSSCDYCSGLGTKTSSDNPSKAVISLRNDKLTSYNFYIAVQDELSKAYYELRTDYAKSHFNKNPDELNENELKTLREVYPFLLSEAALK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ17</accession>
    <name>A0A5C6ZJ17_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">PAS domain S-box protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_05190</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="4">
        <location>
            <begin position="11"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="4">
        <location>
            <begin position="146"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="5">
        <location>
            <begin position="223"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="4">
        <location>
            <begin position="399"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="5">
        <location>
            <begin position="466"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="880"/>
            <end position="1096"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="681"/>
            <end position="715"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD90144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1098" mass="125088" checksum="2D8E5D93308D4ED9" modified="2019-11-13" version="1">MPISMMTDVPNEDLFQNIFQSSVEGILVVDENGGIVMANRACEQLFGYNPEILAGKNIEILIPQQFKQHHKRHFETYTKNPKARAVSKDMDLWGIKKNGIQFSLDISLSPTVIDGKHLTIAFLRDASKRKEDFNKIKNVNNELSGSNRRYNTLLNNLQGIVYRCKNDRDWTMEYISEGCKEITGYSPEYFLEGKVHFSHLIFDEDQDKVWNDTEHGIDKRQPYSLNYRITDKNGHVKYMQELGRGIYDSNGKLEALEGFITDITAKKETELELRRSEFKTKALLEAIPDMMFIQDEFGKYLEFYVNSPENLFLPPKDFIGINMKNVLPPDVYKIIKQSHDKAMASGTMQIAEYSVQGKKGIEHFEARVVLINDHELLTIIRDVTEEKVREDLLSIRNNALASANNSIIIAEAQHQNTRIIYCNDTFEKMTGYTEAETLGRNCNFLQNHDRDQKEIGIMKNAIANGEACNVVLRNYKKDGTLFWNDLTITPVHNENHELTHFIGVQNDVTTKVKEEDLKDKTQKILELIAQDKPILDIGKKIIETVEGHLNEGIATILLLDKETKTLHKLVAPNLPKAFCNYIEGTAIGPKVGSSGTASFLKKEVIVAHIATNVLWEDYKDMALKSGLKACWAFPILSSTNQVLGTFAIYSKLERKPSAKEKEMLLNMTYLASVAIEKHQNITALKESKKELVDYAQKLEEKVEARTKEVMETVQKLVETNLNLEDQIMITKQAESDAIASKSIASEIAKNFPNGFIAVIDKDFKVAFAEGEALAQLGLKEFSKEGILVDDVTVFSEERKTKIKEYTTKTLTGQHLAFEISYKNRYFVVNTAPLYDEHNKISYALHVYNDISEQKAFEFKIQNAFKKEKELSELKSRFVSMASHEFRTPLSAILTSAVLIGKQNEPGKELKREKYVEQIERNVKNMVVILNDFLSLSKLEEGKVQPLLERFDLISFSKLLIKEINPILKKGQTIDFGKANNELWVHLDAKLLRHILSNLLANASKYALPETVIDFIISQNQEKLLIQITDHGMGIPKEEQHYLFDRFFRAKNAANFEGTGLGLNIVKSYTELMGGSIGFESQLNIGTTFWIAFPLNNRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ40</accession>
    <name>A0A5C6ZJ40_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF4138 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022298">
        <property type="entry name" value="Conjug_transposon_TraN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13595">
        <property type="entry name" value="DUF4138"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022793829" evidence="1">
        <location>
            <begin position="28"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="285" mass="32970" checksum="7148EFAD3ED6E1B8" modified="2019-11-13" version="1">MKKHILISALIIVCAFAPRLCSAQATAQTPQILDTIYANDTKNVALFFPEPIRQGVTGADNFVFTYNREKEQYFGLLQAKPGKESNLLVINRNGSIFSYIVKYKKHLSKLNYFVSKASSIGNERPFVNDSTVVKKIEDSVDNKTFYYTKFSSYLLDKRQRIATIQKRNEGIVLSIKNIVFDKEELYFVIEIENKSTLDYDLNFLNLSVETRQKGKKKSLQKLFEEPIFKYKLPQKITEGEVVRLVYVLPKFSISNDRRLVVELNEKNGERDLKLKVSHKYINNPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ60</accession>
    <name>A0A5C6ZJ60_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06265</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="25"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="70" mass="7888" checksum="F5D6E38DC8522E09" modified="2019-11-13" version="1">MTNDVGLKFTCSRLKTHHSQLKAQDSKLKAQNSKLKTQGSKLKAQDSKLKTQTEAQPQYSFAPVGRWLAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ62</accession>
    <name>A0A5C6ZJ62_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Aminopeptidase N</fullName>
            <ecNumber evidence="4">3.4.11.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">ESY86_07370</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal amino acid, Xaa-|-Yaa- from a peptide, amide or arylamide. Xaa is preferably Ala, but may be most amino acids including Pro (slow action). When a terminal hydrophobic residue is followed by a prolyl residue, the two may be released as an intact Xaa-Pro dipeptide.</text>
            <dbReference type="EC" id="3.4.11.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.2" evidence="4"/>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="SSF63737"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022892031" description="Aminopeptidase N" evidence="11">
        <location>
            <begin position="19"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M1_N" evidence="13">
        <location>
            <begin position="55"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M1" evidence="12">
        <location>
            <begin position="322"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="domain" description="Por_Secre_tail" evidence="14">
        <location>
            <begin position="576"/>
            <end position="640"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF17900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF18962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TXD89599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="645" mass="71566" checksum="24105D982F47176D" modified="2019-11-13" version="1">MKTRLLSLCSLIGFTVFAQDYNETINNIREAEAKSALGKMMQRANLNTGNYDLKYNRLELEVNPSVAFIDGEVTTYFEAKSDMDAITFDLASNMVVSAVLQRGNSLSFTQNANDELVISLPTNQAAGQLDSLTVAYSGNPISSGFGSFEQTTHDNEPIIWTLSEPYGAKAWWPCKQDLIDKIDSIDVFLTTPIKTPSNQDYVAVSNGLEQSQTISGSNKTTHFKHRYPIPAYLVAIAATNYEVYSHTVDNNGSPFDIVNYVYPEDLAYAQARTPVTVDIMNLYSDLFEEYPFANEKYGHAQFGWGGGMEHTTVSFMGSLGRNLIAHELGHQWFGNKVTCGSWKDIWLNEGFATYMSGLVIENFDGNDEFTTWKQQVNGSITLQPDGAVYISDADTLNVGRIFSGRLSYNKAAMVIHMLRKKLGDAPFFGALQAYLDAPDLTYGYAKTADFISVVETETETELSEFFEDWLFNEGYPSYTINWNQPEATALHLTISQTQSHPSVSFFESPVTLRLLGNNGQSQDLVLNNSSNNQSYTETVNFDVQTLIFDPESDIISRNNTVVLGTDAFAFDTGITVYPNPSSDLIHIKKAEALQVSELKIYNILGQTLYDSEFSATIDISSMASGLLILQLKTTDGVITKSVLKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJB6</accession>
    <name>A0A5C6ZJB6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_09225</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008886">
        <property type="entry name" value="UPF0227/Esterase_YqiA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05728">
        <property type="entry name" value="UPF0227"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="282" mass="31758" checksum="8EF33F54ADA2C1C3" modified="2019-11-13" version="1">MNILYLHGLNSSLSPEKRKALERYGNVEAPTIDYENNPDSISSLFDQFEDANIDLVIGSSMGGFAGYYLSKLFQLPALLFNPALANRSVFQNIPNAPETNANSIHLVLGSKDSVVITEDTLDFLANLLMQPQNYSIQIRPELEHRIPVEIFEEEVSSLFERLPPGHLKPKRLFLDDIRTVNMVYDTTFEPEFDIVRTYDAFVDYIKKNGLPDFISFDNDLGLGTDGKVAPDGLAAAKWLVYESGLDLRNLHYKVHSANPVAAQQIRGLLGNYIRFLNQRNTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJD2</accession>
    <name>A0A5C6ZJD2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_06610</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022992685" evidence="5">
        <location>
            <begin position="22"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="7">
        <location>
            <begin position="140"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="6">
        <location>
            <begin position="323"/>
            <end position="807"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD89869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="808" mass="91488" checksum="614096328A0154AD" modified="2019-11-13" version="1">MRLKDFKLLIATVLTAFPMLAQNKLSGYVTNQNDNSVVANVEVYDKISGLLTSTDSKGYYEFSSEKNELTLVFYKSEFEIWEQEFSLDGSQTLNIILQPLQRELSEIVINARKAKVFELNRLKDVEGTAIYAGKKTEVVLVEQSLANLATNNARQVFSQVAGLNIYQNDDAGLQLNIGGRGLDPNRTANFNTRQNGYDISADVLGYPESYYTPATEGLKEIQVIRGAASLQYGTQFGGLINFKTKDPNPNKPIELITRNTLGSFGLYTNFTSLSGTKGKFSYYTYFNYKTGDGFRPNSEFESKNVFAHLGYKFDEKTSVSAEFTHLYYLAQQGGGLTDRQFNEDAFQSNRERNWFKVNWLLYNFKLKHKFSEDTNFTFNAFGLNASRDALGFRSNRVDLIDPNEERDLIKGEFRNYGAEARLLSKYDIFGKKATFLIGSKFYKADNKEQQGPGSDGFGPDFDFYDNEYPNYPDQSRFEFPNLNVAVFGENIFYVNDKFSVTPGFRFEYIKTESEGFYKRINTDAAGNVIFEETLDDNRDFERNFVLLGLGLSYKPSTALEIYGNISQNYRSVTYSDINITNPAFAVDPNITDEDGFTADLGIRGNYKNAISYDLDVFGLYYNGRIGFVQKVRDDGRTISERGNVGDARMFGVESLVDFNLKQILGMTNDFSFNYFVNASFINSEYTDSKESGVVGKKVEFVPDANIKSGLRFGYLNLMANVQYTYLSKQFTDATNSEVANLSGVIGAIPQYDILDFSLSYTYKRFKLETGVNNFLDNSYFTRRATGYPGPGIIPSAPRNWYATLQIKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJS6</accession>
    <name>A0A5C6ZJS6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF3078 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_08340</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021428">
        <property type="entry name" value="DUF3078"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11276">
        <property type="entry name" value="DUF3078"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023029578" evidence="2">
        <location>
            <begin position="23"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="23"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="313" mass="34979" checksum="07267937C0E99835" modified="2019-11-13" version="1">MTKKLFLTAAFMFCLALSFAQSKEELQTQKKEKQAEADAAQKEADALQAQIDALPGWKLGAFGTIGGSLSNFNNWFAQGTPSNSSGNIGFTVNAYANFIEDKFFWRNSLNTNLSWVKLNDKEDPTDNDSFEPTTDVFNISSLYGRNLSKKLAASALVEYRTTILDNFNDPGYLDVGIGGTWTPTKNLIVVFHPLNYNFVFANNSAVYESSLGAKIVADYTRQIGKINFKTNFATFQSYNSSDLSNFTWINSFSYTLWKKIGVGFDFALRSNHQEALSYALGLLPADYMGDPLTFDNVDNDLQTYYTVGLSYKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJU7</accession>
    <name>A0A5C6ZJU7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03720</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022959647" evidence="1">
        <location>
            <begin position="19"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="139" mass="15340" checksum="0D0BBA4686B69BCB" modified="2019-11-13" version="1">MKKLLVLLVCALSLQVTAQSSGQNWLTNYKTALTTAASLNQPILTFVTDGSNSKALQLLEQELFDTETFRSLKGKVVFLKMDVTSSNVDARRHATHFTKSESVPALGLVDQYKEMIGEPLNEITSENINAFIALLNTTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJW2</accession>
    <name>A0A5C6ZJW2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">FtsX-like permease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_05780</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="291"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="335"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="375"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="26"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="322"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD90246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="417" mass="46124" checksum="C9EEBA06E8AC82CB" modified="2019-11-13" version="1">MLVYLRLFAESFSFAINALRNNKLRTFLSLLGITIGIFSIIAVLAAVDSLDKTIKDQLSGLDKNTMYLARFSFGPTDVPTWKRLQFPEVSYTEYKYLKSTLSDAENMAFQLFVKRENISFESKSVNRVNTVVASHEFEDIQALKFSKGRFYSESESNSGRPVVVIGDDIANQLFGSLDPIGKRVRIYGQKFTVIGVVKKEGSGLFGDSNDVSMFLPANYVRNRFGDNNKNMNHIIIIKPTEDVDIDALKAEVTQLMRSQRGLKPDEIDPFFISVISGLQDAIDDIISTLNIIGWVISGFSLLVGGFGIANIMFVSVKERTSLIGIQKSLGAKNRFILFQFLFEAVILSILGGIVGIIMVWLVALAANAFVEDFTFVLSFFNIFLGFALSTVIGLISGVIPAISASKLDPVEAIRTGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK03</accession>
    <name>A0A5C6ZK03_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HupE/UreJ family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_04470</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032809">
        <property type="entry name" value="Put_HupE_UreJ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13795">
        <property type="entry name" value="HupE_UreJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="190" mass="21601" checksum="7163B4813A7120F0" modified="2019-11-13" version="1">MMDFTFYLKEGVNHILDFDALDHLYFIVSFCLIYTFQDWRKLLGLVTAFTVGHCLTLFLSGMQLVSIDADLVETLIPITILLSCLNNYWMLAKVNPQQQSVVVTYFILLAFGLIHGLGFSNYIKMMIFDDESVVLPLLGFNVGIEVAQLIIVALFLGVMALVHIKTNKLKWVRLAINTVIVVLVLQMIFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK68</accession>
    <name>A0A5C6ZK68_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_05690</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013211">
        <property type="entry name" value="LVIVD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08309">
        <property type="entry name" value="LVIVD"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="407" mass="45462" checksum="9974582B76B4EA3F" modified="2019-11-13" version="1">MKNFALFLVVCFLWSCNKDDQVETYTYTLGIPETMTKVEWRSQVAVQAPKPIASVGKIYAYQNYIFINEKHKGVHVIDNSDPTAPQVVSYINIPGNEDISIKNDFLYADNAIDLVVFDISNINLIHEVERLEDVFNYYSDYQMPAEVQAADYSNFDADSQVIVGWRVEERTEIVNYNESFFSDNSLATNTVGTGGSLARFQIVNDFLYTVGSFELKTFDISNLSQPNLVNTNTAGWNIETMFHADGFLYLGGSNGMFINSIANPAAPEYVSMFTHWDGCDPVVVDGDYAYLTLRGGNACGQELSTLEVIDISDKSNPTLVAQHALDSPYGLGFKGNDLFVCDGASGLKIYDKTNPLDLQLLHVFSDVQATDVIPLEDRLLMISDAALYQYNYDDQNNIVLLSTFNLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKE2</accession>
    <name>A0A5C6ZKE2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06255</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="209"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="235" mass="27683" checksum="EE08C22803456B89" modified="2019-11-13" version="1">MQDFLINNDEFFTKFFELAAAVSGSIYLNKTKHKTIRIFVYYLWLTVVVETLGVYTQILQNNYDYEWYIALKNSVFCPNTWLYNIYSFLAIGLIGIFYSGLLSSKKFKIIIRGSIVAYSLFTIVFFLQTNAFFVMSLPYNMLLGTMIICVFVVLYFLELIRSEVLLKFYKLPSFYISVALLFWYLCVAPLFIFGSYYRAVNTDFIQFRVLLLLIINILTYSCFSFGFIYSLYKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKF5</accession>
    <name>A0A5C6ZKF5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022677863" evidence="1">
        <location>
            <begin position="22"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="255" mass="28544" checksum="8B3B813EA115D746" modified="2019-11-13" version="1">MKKNSLIMLCLAFLGTLGAKAQRKTIDGQIFASGEVVGVNIINKTAGRYDISDDEGRFEIAAQVGDTLIISALQYMIKEIGIDAGIVRSKQVLVNLEDNVTALDEVRVGKVLTGNLLLDIGNSEAKREPNFYDLGIPGYTGRRKTQSERRLNEATTGGGIVPLNPIINWITGRTKQLKNRVKIEDQDLRMNRTRSELAEVLFEIDNLAELKRNEFFFFAAEDPKFLELSKQDNDLAMVEYLTAKLKEFKSRNEGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKM3</accession>
    <name>A0A5C6ZKM3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_02620</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019238">
        <property type="entry name" value="AbiEi_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09952">
        <property type="entry name" value="AbiEi_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="333" mass="38442" checksum="59A738B51180EDA6" modified="2019-11-13" version="1">MYRNNDFIYEATSKLEELINIPIQIDSNKDNYHALLTIGNAQFLVETKSAIRTSNQGFILSQLEEIKNNNSRPIILIAEYISKKATEELKKRGFNYIDVAGNAFIKYKYLAIFVEGQKNNKKDKTNQSRAFQETGLKIIFHLLNKPEHLQDSYRRIAEQSNVSVGSVSNVMAELEELNYLLKTNNKRILKNKTELLERWVVDFNATLRPRILRKRMRFIDPDHQKKWRDINLHSENGSILWGGEPGGALLTDNLRPEQFTVFTDLELSQVASKLHLAPSEDGNLEILQKFWKNNLNNNQVVPSLLIYADLINSGFGRNIETAKKILENELQHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKR2</accession>
    <name>A0A5C6ZKR2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type 1 periplasmic binding fold superfamily protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05495</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023109013" evidence="1">
        <location>
            <begin position="24"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="183" mass="19226" checksum="C65C2AA3BDD9A078" modified="2019-11-13" version="1">MRNLKFLATAIFATVLFVSCSNDDDTPEEVNEEEVITTLTVTLTPDGGGTPVTLQTRDLDGDGPDAPVITTGNLAAGVTYNGSIVLLNETETPAENITLEVEEEDDEHQFFYTIGGGLDVTTAYANFDGDGNPLGTQFTLTAGAVSSGTLTFTLRHEPMKPNTGLGDAGGETDIAASFNVMVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL11</accession>
    <name>A0A5C6ZL11_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="4">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_04815</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="4"/>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="SSF47005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3 4" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="6">
        <location>
            <begin position="3"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="7">
        <location>
            <begin position="135"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="78"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="179"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD90077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="456" mass="49721" checksum="BCA05C6ADA94A7E9" modified="2019-11-13" version="1">MAKFELKLPKMGESVAEATVTSWLKNVGDKIEADEAVFEIATDKVDSEVPSEVDGVLIEKRFEVDDVVQVGEVIAIIETEGEDNETETETETEVESESTSNETKEEATSHVAEVSNTVTAAKAQTEAVSSTEARFYSPLVKNIAKKEGIPQSELDTISGTGKDDRVTKNDILDYVAHRGSKSAQNASESAQAPPAKAADPKAAEQKSAAEPKKPAPIVASGEDEIIEMSRMGKLIAHHMVESAQTAAHVQSFIEADVTKIWNWRKKVKDSFAKREGENLTFTPIFMEAIAKALRDFPMMNISLQDNKIIKKKHINLGMAAALPDGNLIVPVIKDADQLNLVGMTKKVNDLARRARENKLKPDDIQGGTYTVTNVGTFGSIMGTPIINQPQVGILALGAIRKVPAVVETPEGDFIGIRYRMFLSHSYDHRVVNGALGGQFVKAVKDHLEAWDSNREI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL55</accession>
    <name>A0A5C6ZL55_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_00325</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="81" mass="9421" checksum="36B14F750527BB18" modified="2019-11-13" version="1">MGSLTVSNKILDKYFGYLKNLDSKSKRSLIDKLTRSIETKSRNDIELNKMFGAWKDNRDSDEIISEIKDSRINKTITESFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL77</accession>
    <name>A0A5C6ZL77_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Endonuclease/exonuclease/phosphatase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_08390</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19580">
        <property type="entry name" value="Exo_endo_phos_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022880839" evidence="1">
        <location>
            <begin position="24"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="Endo/exonuclease/phosphatase" evidence="2">
        <location>
            <begin position="36"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="361" mass="41008" checksum="9795BC91B1E977A3" modified="2019-11-13" version="1">MNLKSIHFSIALLCLLISFNGLAQDLNKERRFKIHTVAFYNLENLFDTINDPIKFDEASPIMEMKTNRAEVYAKKVHNMARVVADIGAEVSGNSPAVIGVCEVENRSVLVDLVNDPLLLGKDYGIIHYESPDARGIDVALLYQKKLFKPSNHSSHQVDLFKDGNSRERKYTRDQLLVSGMLDGELIHLIVNHWPSRSGGEAKSRPNRVAAAKVSKRLIDSLQAKDPYAKVFMMGDLNDDPTNASLKEVLKTKSDKEDLDLKGLYNPYEDMFVKDGFGTTAYRDAWSLFDQIVMTKPLTDTEDYESFRLYKAGIYNKLYLTNKRGRYKGYPLRSFSDGGFTDGFSDHFPVYVYLIKEVKDDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLD7</accession>
    <name>A0A5C6ZLD7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="114" mass="12524" checksum="6A0791142DC0BEF2" modified="2019-11-13" version="1">MDSIKNNTVTTNEGKNTAIIAYITIIGLIIAFVMNSDKKSDFASYHIKQSLGLALTGLALGIIGMIPILGWIINLIGIFVLLFIWIMGLVNAINGQEKPVPILGTMYLEWFKNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLH4</accession>
    <name>A0A5C6ZLH4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">IS200/IS605 family transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">tnpA</name>
        <name evidence="2" type="ORF">ESY86_00600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002686">
        <property type="entry name" value="Transposase_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036515">
        <property type="entry name" value="Transposase_17_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01797">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01321">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143422">
        <property type="entry name" value="SSF143422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Y1_Tnp" evidence="1">
        <location>
            <begin position="6"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="150" mass="17760" checksum="D373216265078514" modified="2019-11-13" version="1">MGQSLVKNYLHIVFSTKYRQKLIHAPYEKELHAYIGGVCNELECTVLIVGGYTDHIHILCMLSKKIALMNLVQKVKANSSKWYKTKDKRLEDFFWQDGYGAFSVNPKGVDVVYRYIQNQHAHHEKTEFQTEYRAILKKHKVEYDEKYVWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLM5</accession>
    <name>A0A5C6ZLM5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_05390</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="273" mass="32981" checksum="BEECA35A34F07D77" modified="2019-11-13" version="1">MLNCFTDYEFTENLKKGRKEIRLQISRYQSELYTDGWGRPLENPLNETKYLVKKSKNKLTRFNPRITVLFEDKEQSYYVNIVDGVNKNTDEKGFLLLNEFRNKDTNDKSEILKDRLYKTPLEAFHYAHNRMESIVNNDFEEYLKNKKKEIRKRQRIPRKRVRDFINSCNENDLDGILKNLDKNFIFKKNVKWKTESEFNGIEEFKKYIESKDQNLCCIGFKIRSSWNINLPFSITIGVKYFPDSTNKDNITLKYRQYIFEFKDDKIIRITEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLN1</accession>
    <name>A0A5C6ZLN1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF3276 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_00990</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032422">
        <property type="term" value="F:purine-rich negative regulatory element binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021694">
        <property type="entry name" value="DUF3276"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006628">
        <property type="entry name" value="PUR-bd_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11680">
        <property type="entry name" value="DUF3276"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00712">
        <property type="entry name" value="PUR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="92"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="92"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD91194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="133" mass="15829" checksum="05369F51518EEC6A" modified="2019-11-13" version="1">MSDYERMDKEEIFSKVLRAGRRTYFFDVRSTKAGDYYLTITESKKFTNDDGSFHYKKHKIYLYKEDFTEFNEILKEMTDYIIDEKGGEVISERHQKDFKKEEYNDTNTPDEADDASENKASADKFTNISFDDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLT6</accession>
    <name>A0A5C6ZLT6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">3-phosphoglycerate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_00145</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2-Hacid_dh" evidence="2">
        <location>
            <begin position="5"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="2-Hacid_dh_C" evidence="3">
        <location>
            <begin position="128"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD91046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="320" mass="34542" checksum="F2027A58C1A6C72C" modified="2019-11-13" version="1">MKVLANDGVSQSGIDALEQAGFEVLTTTVAQEQLISYINEHQIDVLLVRSATTVRKDMIDACENLKIIGRGGVGMDNIDVEYARSKGKHVINTPAASSQSVAELVFAHLFGGVRFLYDSNRLMPLDGDTKFKTLKKNYANGVELRGKTLGIIGFGRIGREVAKIGLGVGMKVIASDKFVGKANIKVEFYNGQYINVEIETQTMEEILLQSDFITVHVPAQEDYIIGKAQFDAMKDGVGIVNAARGGVINEVDLVKALENGKVAFAGLDTFESEPSPAVQVLMNGRISLTPHIGAATNEAQDRIGTELAEQIISLLKTEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLY9</accession>
    <name>A0A5C6ZLY9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_01670</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="25"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="276" mass="31095" checksum="5E08EA582A4D9123" modified="2019-11-13" version="1">MPFITNKTKDKAVDIFYEDYGSGQPVILIHGWPLSRKSWEQQVWKIVEAGYRCISYDRRGFGISSAPWDGYDYSSLTGDLNELIKQLDLKDAVLVGFSMGGGEVVRYFTDYGSDRIAKAALISSIIPLVKKKDDNPDGVPEEAFEDIKDALEQDRLGFLKNFGKGFYNYEKNRDRVSQGILDYDFSIASHASPRATIETAKAWMDTDFRTELKNVDKPTLIVHGDADETVPMQTSAKQAAKGIKNNQFEIIKGAPHGLNITHKDELNKILIDFLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM18</accession>
    <name>A0A5C6ZM18_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Probable dual-specificity RNA methyltransferase RlmN</fullName>
            <ecNumber evidence="11">2.1.1.192</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">23S rRNA (adenine(2503)-C(2))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">23S rRNA m2A2503 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Ribosomal RNA large subunit methyltransferase N</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">tRNA (adenine(37)-C(2))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">tRNA m2A37 methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11 13" type="primary">rlmN</name>
        <name evidence="13" type="ORF">ESY86_02465</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>adenosine(2503) in 23S rRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2-methyladenosine(2503) in 23S rRNA + 5'-deoxyadenosine + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42916"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10152"/>
            <dbReference type="Rhea" id="RHEA-COMP:10282"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74497"/>
            <dbReference type="EC" id="2.1.1.192"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>adenosine(37) in tRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2-methyladenosine(37) in tRNA + 5'-deoxyadenosine + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:43332"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10485"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74497"/>
            <dbReference type="EC" id="2.1.1.192"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="11">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="11">Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the radical SAM superfamily. RlmN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.192" evidence="11"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070040">
        <property type="term" value="F:rRNA (adenine-C2-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002935">
        <property type="term" value="F:tRNA (adenine-C2-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01849">
        <property type="entry name" value="RNA_methyltr_RlmN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040072">
        <property type="entry name" value="Methyltransferase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027492">
        <property type="entry name" value="RNA_MTrfase_RlmN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004383">
        <property type="entry name" value="rRNA_lsu_MTrfase_RlmN/Cfr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30544">
        <property type="entry name" value="PTHR30544"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006004">
        <property type="entry name" value="CHP00048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00275">
        <property type="entry name" value="adenosine_C2_methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00048">
        <property type="entry name" value="rRNA_mod_RlmN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 11" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9 11" id="KW-0408">Iron</keyword>
    <keyword evidence="10 11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 11 13" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="7 11" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 11 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="11" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Radical SAM core" evidence="12">
        <location>
            <begin position="100"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="11">
        <location>
            <begin position="165"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="11">
        <location>
            <begin position="220"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="94"/>
        </location>
    </feature>
    <feature type="active site" description="S-methylcysteine intermediate" evidence="11">
        <location>
            <position position="339"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="296"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TXD90842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="346" mass="39411" checksum="578FFB49C877AA40" modified="2019-11-13" version="1">MEIKKKDIRALTKEQLRTFFETQGDKAFRGNQVYEWLWGKAAHSFEDMTNVSKETRQMLEAHFVINHIKVDQMQRSSDGTVKNAVRLHDGLVVESVLIPTKSRTTACVSSQVGCSLDCRFCATSRLKRMRNLNPDEIYDQVVAIDNESRLYFDRPLSNIVFMGMGEPLMNYNNMIKAIDKITSPEGLGMSPKRITVSTSGVPKMIKKMADDEVKFKLAVSLHSAIDEIRTSIMPFNATFPLDDLRESLEYWYAKTKNRITYEYIVWDGINDKKSDVEALIKFCKFAPSKVNLIEYNPIDDGEFQQANTEALDMYVSMLEANHITVTVRRSRGKDIDAACGQLANKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM71</accession>
    <name>A0A5C6ZM71_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Acetolactate synthase</fullName>
            <ecNumber evidence="4 8">2.2.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">ilvB</name>
        <name evidence="12" type="ORF">ESY86_02285</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>H(+) + 2 pyruvate = (2S)-2-acetolactate + CO2</text>
            <dbReference type="Rhea" id="RHEA:25249"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58476"/>
            <dbReference type="EC" id="2.2.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
        <text evidence="8">Binds 1 thiamine pyrophosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 1/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the TPP enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.6" evidence="4 8"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00055"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00059"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003984">
        <property type="term" value="F:acetolactate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd02015">
        <property type="entry name" value="TPP_AHAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012846">
        <property type="entry name" value="Acetolactate_synth_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039368">
        <property type="entry name" value="AHAS_TPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012000">
        <property type="entry name" value="Thiamin_PyroP_enz_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000399">
        <property type="entry name" value="TPP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045229">
        <property type="entry name" value="TPP_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18968">
        <property type="entry name" value="PTHR18968"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00205">
        <property type="entry name" value="TPP_enzyme_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00118">
        <property type="entry name" value="acolac_lg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00187">
        <property type="entry name" value="TPP_ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="6 8 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TPP_enzyme_N" evidence="11">
        <location>
            <begin position="21"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_M" evidence="9">
        <location>
            <begin position="212"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_C" evidence="10">
        <location>
            <begin position="407"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TXD90808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="578" mass="63049" checksum="F5B5FAED1372C367" modified="2019-11-13" version="1">MKATQTIQKETNNSQVTERISGSEAVIKCLLAEGVDILYGYPGGAIMPVYDELYKYQDRIHHVMTRHEQGATHAAQGYARISGKVGVAIATSGPGATNLITGIADAQIDSTPMVCITGQVGSHLLGSDAFQETDIVGISTPVTKWNHQITKASQIPEVMAKAFYIARSGRPGPVLIDITKDAQFEEFDFKYEKCTGIRSYKPVPKTDEATLKAAAEAINAAKKPFIVWGQGVILGKAEDAFKAVIEKAGIPSAWTILGASAVPTSHPLNVGMVGMHGNYAPNVLTNDCDVLIAIGMRFDDRVTGNLASYAKQAKIIHFEIDPAEVDKNVKTDIAVLGDAKASLEALLPLLEEKTHQEWHQRFKDLYDVEYEKVIKHDLYPTKEGLTMGEVLKEINIQTKGDAAIVSDVGQHQMVACRYANFNKTKSNITSGGLGTMGFALPAAIGAKMAAPDREVVAIIGDGGYQMTIQELGTIFQQKTPVKIVVLNNEFLGMVRQWQQLFFEKRYASTEMVNPDFVAIAKGYSIAANKVTKREDLKEAVKTMMETEGPYFLEVRVEKEGNVFPMIPTGASVSEIRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM98</accession>
    <name>A0A5C6ZM98_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">HAMP domain-containing histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_01000</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="247"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="293"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD91196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="512" mass="58625" checksum="2BDFCCBDD02B0504" modified="2019-11-13" version="1">MSLSLIGIIFVQAYFINNTLENEEKQFTLNVKRSLSLVSKAIENQELLSYDKLYQQIIDDGINPDSTEIKQRLVFNTYDESTDQYTVFKNAISEESFKVPSLFFDIGADSINVSRFSNISETQVFQKTDIDGTIDIKPIKKYSGYNTLDDIGKAVYKSVYRERYKNIPIYKRITTDAVSKLLSNQLTNSGINTPFQFAIYDRDLSTKIQSEDFNLKPESTIGVPVFLDNNNQSDYNLYVDFPERKGYLLSSILGMIVLSIIFTSIIILAYSSAIYQLIRQRQISQIKTDFINNMTHEFKTPIATINLALDSIKNPKIIGDQEKVMRYLKMIKDENKRMHAQVENVLRISKLEKNELNINKDREDLHSLIEDAIMHVELIVEDRQGFVHSHLEAERSTVLANETHFTNVIVNVLDNAIKYSEEPPKIDVYTENVGNSILLKIIDQGNGMSKQVQKRVFEKFYREHTGNVHNVKGHGLGLAYVKRIIDDHQGHISVESEKGKGSTFTIKLPLIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMG2</accession>
    <name>A0A5C6ZMG2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fasciclin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_06445</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02469">
        <property type="entry name" value="Fasciclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00554">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="SSF82153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50213">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022735282" evidence="1">
        <location>
            <begin position="26"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="2">
        <location>
            <begin position="70"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="218" mass="23079" checksum="E3C48F1EFEE5AE9E" modified="2019-11-13" version="1">MKTSKKLVGIALLSATMFVGFNGTAQEKKETKKEMANKVEKKMDKKMSVEKTMMPDAEVKTVGGAKMFPTRNIVENAINSKDHTTLVAAVKAADLVETLTSEGPFTVFAPTNEAFEALPEGTVATLLKPENKDQLQSILKYHVVAGNYSAASIGKLIADNNGEAKLATVAGGNLIATAKNGKVYITDENGNSAEVTIADVNQSNGVIHVVDAVVLPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMK0</accession>
    <name>A0A5C6ZMK0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Copper oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_02775</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13848">
        <property type="entry name" value="CuRO_1_CopA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd13896">
        <property type="entry name" value="CuRO_3_CopA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001117">
        <property type="entry name" value="Cu-oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011707">
        <property type="entry name" value="Cu-oxidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033138">
        <property type="entry name" value="Cu_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002355">
        <property type="entry name" value="Cu_oxidase_Cu_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034284">
        <property type="entry name" value="CuRO_1_CopA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034279">
        <property type="entry name" value="CuRO_3_CopA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11709">
        <property type="entry name" value="PTHR11709"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00394">
        <property type="entry name" value="Cu-oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07732">
        <property type="entry name" value="Cu-oxidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00079">
        <property type="entry name" value="MULTICOPPER_OXIDASE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00080">
        <property type="entry name" value="MULTICOPPER_OXIDASE2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022681776" evidence="3">
        <location>
            <begin position="20"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="6">
        <location>
            <begin position="42"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="4">
        <location>
            <begin position="163"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="Plastocyanin-like" evidence="5">
        <location>
            <begin position="472"/>
            <end position="586"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07731"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD90898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="783" mass="89510" checksum="A5AA85610F2871A2" modified="2019-11-13" version="1">MKMRLLVVLLLCISFGASAQLTANKTEENVDNWPERVYDLTIDYKTVNFTGKDIKAMTVNGGIPGPNLEFNEGEFAIINVTNAMDEETSVHWHGLILPNFYDGVPYLTTPPIKPGETLQYKFALKQSGTYWYHSHTGLQEQRGVYGSIQINPKETNLEYDKDLVLVLSDWMDENPKSQLKNLKRGNEWYLIKKGQIQSWDKIIKKDAVGAKLKMMWQRMPDMAILDNYYDRFFINGQPTQDYNDFEPGEKVRVRFVNASAATYFWLTFGGNDPMLVASDGLKVVPIQKNKTLIGVAETYDFIVTIPENAKLEIRATSQDGSGQASAYLGDGDLLKAPVVPEPDLIESIKHMMAMDMKMGAPAAKFNPSKNDSIKYMKKYAMKMDGMAMNDDMKAGDVSKKTDSMSMNQDKMDMKMNDKSMKNGDMKDMKMGYIIPKDKVIGDNMKTGANPEFNYNYLRSPEPTAFESDKPVKEILFNLTGNMNRYVWSINGVPLSETDKIKIEQGEVVRITLNNLTMMHHPMHLHGHFFRVLNENGEYSPLKHTVNVAPMQKVVIEFDASEQGDWFFHCHILYHINSGMARVFSYDTPRDERLKAFPLKNLTNEADHIYTWGEVTAASHMTEFFYTATNIRNQFILRGEYGWNENLEAEFTYERWLNSYFRVFGGVNVENEMEDSMDEIGATGVVGVRYLLPLLIDSDLRIDNKLRPIISLSTATMIFRRVAIFGEYEYQMDFGWVNDFEAGTDFKEETVWKLGLEYVLSRDFSLMGSYDNRFGAGGGLSLRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZML5</accession>
    <name>A0A5C6ZML5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">RecQ family ATP-dependent DNA helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_06705</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004589">
        <property type="entry name" value="DNA_helicase_ATP-dep_RecQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032284">
        <property type="entry name" value="RecQ_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16124">
        <property type="entry name" value="RecQ_Zn_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00614">
        <property type="entry name" value="recQ_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="5">
        <location>
            <begin position="25"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="6">
        <location>
            <begin position="217"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD89887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="636" mass="72450" checksum="2FEBA1CAB1819244" modified="2019-11-13" version="1">MSHPINILERYWQHTSFRPLQEEIITAVLNNEDTFVLLPTGGGKSVCFQVPALVKDGICIVISPLIALMKDQVNALKLKGIKAMALTSGISYQDLDTLLDNCIYGNYKFLYLSPERLQQDIVQQRIAQMNVNLIAVDEAHCISQWGNDFRPAYLNIALLRELLPSVNVIALTATAKPNVIEETMSALDFIAPKVFRASFERPNIAYKVFYSEDKLYDLEQVLKKYPGASIIYVRSRKASVEIHDQLTKLGFDATFFHGGIPNKEKQERLDHWMNNRKRIMVATTAFGMGIDKPDVKTVVHMNLPESLESYYQEAGRAGRNNEKAHAILLYNASDEILLKNQFIRSLPSIDAIKLVYRKLCNYFQIPFGEGETSMHQFDFNDFCKTYDFNPLQTYAILQLLDRNSIIKLSQQFNYKTRLQFILSNAAVFHYLERHQSFQTIVKSILRTYGGIFEHELAINLHLIATKASTSEKEIIAVLNTLKRDGVAEFMFSNTDSEIVFIQPREDDMTINRIAKTVEQQMALKTMQVNSVLEYIKNDDVCRSVQLLSYFGEETGKPCGICSVCTAKGAKKTALVHSEKQLEQTLVQILSTRACNSRQLTEQCKAPKEQVLKAIKNLLELQKIECTEANTYRLKNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNX8</accession>
    <name>A0A5C6ZNX8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SDR family oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_01500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000534">
        <property type="entry name" value="Semialdehyde_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00859">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Semialdhyde_dh" evidence="1">
        <location>
            <begin position="3"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="213" mass="23212" checksum="9564D429AE3A7472" modified="2019-11-13" version="1">MENVLIAGAHGTTGKQIVNLLKQSQYFKPVAMVRTEDQVKQFENEGVATVLADLEKDLAHAVIDIDKVVFAAGSGGKKVIEVDQEGAKRLVDASKQANVKKFVMLSSMGADAPEKAEELQDYLKAKHNADEYLKQSGLNYAIVRPGSLTNNKATDHIQLKEKLNKRGEISRADVAQTLVRSLNDDTANKATFEILEGDTLIGKAMDTLSEVKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZP90</accession>
    <name>A0A5C6ZP90_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PorT family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_00750</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025665">
        <property type="entry name" value="OMP_b-brl_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13568">
        <property type="entry name" value="OMP_b-brl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023046030" evidence="1">
        <location>
            <begin position="23"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="OMP_b-brl_2" evidence="2">
        <location>
            <begin position="20"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD91151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="205" mass="21917" checksum="7CFB59CBA0C34C79" modified="2019-11-13" version="1">MKKLMLCAAVAVLGFTTVNAQAIRFGAKAGVNFANLSGDDVENADGRTGLNAGLVAEIGITETFKVQPEVLYSQQGLQEDFQGGESKLKLDYINVPVMAKYYVAEGFALEAGPQFGFNISSKYEIQIEGQDGEELASTQSDVEDGVEAFDFGIGGGVSYTLPSGLFVQARYVHGLTSVYQGSNEGVFQDDLNNSNLSVSIGYFFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPE9</accession>
    <name>A0A5C6ZPE9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hpt domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_03960</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="SSF47226"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50894">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HPt" evidence="2">
        <location>
            <begin position="17"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="1">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="113" mass="13136" checksum="6250672EF7A809CD" modified="2019-11-13" version="1">MEQTYKLYRVRELADDDEDFVKSLVEAFLEELPEDAQRLNTAVGNKDYKETYQAAHKMKPTIDLFELGVLEELIVVQDWGKLEKSKEDCTNELQMVLNAIQNASMEMKADFKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPG8</accession>
    <name>A0A5C6ZPG8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Cardiolipin synthase</fullName>
            <shortName evidence="12">CL synthase</shortName>
            <ecNumber evidence="12">2.7.8.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">cls</name>
        <name evidence="14" type="ORF">ESY86_04060</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>2 1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) = a cardiolipin + glycerol</text>
            <dbReference type="Rhea" id="RHEA:31451"/>
            <dbReference type="ChEBI" id="CHEBI:17754"/>
            <dbReference type="ChEBI" id="CHEBI:62237"/>
            <dbReference type="ChEBI" id="CHEBI:64716"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cell membrane</location>
            <topology evidence="12">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the phospholipase D family. Cardiolipin synthase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.-" evidence="12"/>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008808">
        <property type="term" value="F:cardiolipin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032049">
        <property type="term" value="P:cardiolipin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01916">
        <property type="entry name" value="Cardiolipin_synth_Cls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030874">
        <property type="entry name" value="Cardiolipin_synth_Firmi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022924">
        <property type="entry name" value="Cardiolipin_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027379">
        <property type="entry name" value="CLS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13396">
        <property type="entry name" value="PLDc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00155">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04265">
        <property type="entry name" value="bac_cardiolipin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 12" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 12" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8 12" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="10 12" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="11 12" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="13">
        <location>
            <begin position="215"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="13">
        <location>
            <begin position="397"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="220"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="222"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="227"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="402"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="404"/>
        </location>
    </feature>
    <feature type="active site" evidence="12">
        <location>
            <position position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TXD90550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="484" mass="55256" checksum="998D858AB62B4FFC" modified="2019-11-13" version="1">MNWVLLLQIAYIILVILVILRVLYDTRSGTKTLAYILFVVFVPFVGMIFYFSFGINYRKRKLYSKKMLMDEPLRKSLTHKMDIYSETISKSGLIAERRATLVEFIRRSGNSPLTANNELKLLVNGEEKFPVLLEALEKATCHIHLEYYIYEDDLTGNQVAELLIRKAKAGVEVRFMYDDFGSHDLKKSFLKKLNDAGVQTAPFYKVKWYALANRLNYRNHRKIVIIDGSVGFVGGINMSDTYRNDLDEAKHLYWRDTHLMIHGQATAYLQYLFMADWNFCSTTPLEYAEGYFPDSTRQYAIGDEVLQFAASGPDSTQPVILYALLQAIASAKKRIHITSPYFIPGESMMDALIIAIKSGLDVKLIIPGVSDSKMVNTAASAYYTELLQYGAKIYKYNKGFVHAKTMVIDDDLAIIGSANMDYRSFDLNFEVNAMVYSKNMTAQLSEVFENDLKASVQIDAAAWGNRPKRVHLWEKVVRLLSPFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPM1</accession>
    <name>A0A5C6ZPM1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">YeeE/YedE family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_04320</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0394 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007272">
        <property type="entry name" value="Sulf_transp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04143">
        <property type="entry name" value="Sulf_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="64"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="119"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="160"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="Sulf_transp" evidence="8">
        <location>
            <begin position="122"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD90600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="186" mass="20112" checksum="06FBA8106A9B7DD2" modified="2019-11-13" version="1">MEYLIQPWPWYISGPLIAIVMFTLIYFGKTFGMSSNLRTFCAIGGAGKKTEFFDFDWKAQRWNLIVVLGAVIGGFIAHFLLSAPVAIDLNPKTVSDLSQLGFKNAGDALLPPELYSWDALLSFKGLAILIVGGFLVGFGTRYAGGCTSGHAITGLSNLQLPSLIAVVGFFLGGLVMIHLLFPLIFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZQA0</accession>
    <name>A0A5C6ZQA0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Amino acid carrier protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ESY86_02470</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the alanine or glycine:cation symporter (AGCS) (TC 2.A.25) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015655">
        <property type="term" value="F:alanine:sodium symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001463">
        <property type="entry name" value="Na/Ala_symport"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30330">
        <property type="entry name" value="PTHR30330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01235">
        <property type="entry name" value="Na_Ala_symp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00175">
        <property type="entry name" value="NAALASMPORT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00835">
        <property type="entry name" value="agcS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="8" id="KW-0769">Symport</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023106438" evidence="9">
        <location>
            <begin position="23"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="248"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="303"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="329"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="384"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="424"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="459"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="496"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="543"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="582"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="629"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="653"/>
            <end position="674"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD90843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="699" mass="75394" checksum="4F2A053A20AD765D" modified="2019-11-13" version="1">MTKSRLFALLALLLINFTNSIAQVQSSGKMEVHLELLNPSSEINNGTAKVSIEGGLAPYQYKWSNVNTPLIASESVGLIEGMEHSVLVSDASGNKVSKTFTIPAKSITEIFNSKVQPAVDVLGAVLFWDAFATLGIYDPVVYTSYKNIPLPRIEVSTDEEYLVKKWLAPEGSQVKKGVEIALLEGNNNTAFSVYAPAEGTLEHDTKEGSLISRLPETGSFNAPLLGIIQFQDPQPLLHPNGDVKTNNIPFIVVWLILGSIFFTLRLKFINIRGFRHSLDLARGKYDDPDAPGTITHFQAMATAVSATVGLGNIAGVAVAISLGGAGATFWMFLAGFFGMSLKFAECTLGVKYRFIDHDGRIFGGPMNYLRYGLEKRNLKNLGKFLAVLFAVLGVGASFGGGNMLQSNQAFKIVSEQIPFLQGQGFWFGIGFALLVGVVIIGGIKSIAQVTAKVVPGMAILYVLGCLIVIGYHFEYIGGAFLAIYDGAFSAEALKGGFIGVLIIGLQRAAFSSEAGVGSAAIAHSAAKTNHPIADGFTSLVEPFIDTMLVCTMTALVLIFTGMHETSSGLGGVELTADAFGSVVSWFPSVLAVAVFLFAFSTMVSWSYYGMRSWTFLFGRSKKVELIYKVMYLGFVVLGASVSLGAVLSFADMMILAMSFPNIIGLYIMAPEINADMKIYWQKLKDGKLYINPRFLKSED</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZQI3</accession>
    <name>A0A5C6ZQI3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ESY86_00985</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="141"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="166"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="246"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="287"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="19"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="342"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="376"/>
            <end position="383"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD91193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="585" mass="65777" checksum="4394E87DDA662FC5" modified="2019-11-13" version="1">MKELKHINKYFYKYRFQLLLGILITIVAKVFALFTPRLIGNAVTTISHAIKGTITTETFRHDLGQSILYLIGAAVVAGILTFFMRQTIINVSRYIEFDLKNEVYQQYQNLSLNFYKSNKTGDLINRISEDVGKVRNYTGPAIMYTINMITLFGVAFIYMFNTAPSLTLYTILPLPVLSFIVYKLSAVINKRSRIVQEYLSTLSAYTQESFSGISVIKSYGIETQNYAEFNTLSTESKEKQIDLAKVQALFFPSMILLIGVSNILVAYVGGVQYMNGQIAELGTIAEFLIYVNMLTWPVATVGWVTNLVQQAEASQKRINEFLKEVPEIKNHTNTQTPIKGRIAFENVTFIYSDTNIQALTDVNFTLEKGETLAILGKTGSGKSTILDLIGRLYDVQKGSIKIDDRIIDQINLKNLRDNIGYVPQDAFLFSDTIKNNIMFGKEDATEDEVIEAAKNASVHKNIMKFNKAYNTKLGERGITLSGGQKQRISIARALIKAPEIMLFDDCLSAVDTETEEKILNNLRTVSDGKTTIIVSHRVSSAKNADKIIVLSEGKIIQTGTHESLIDKDGYYRDLYLKQLSTKEME</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZA65</accession>
    <name>A0A5C6ZA65_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19390</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000039">
        <property type="protein sequence ID" value="TXD86772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="99" mass="11790" checksum="ADF2DA83700EF221" modified="2019-11-13" version="1">MTGFTEPREFKQFFANHFTPCMIHNPSEREDVGGKHQHRQLNHEKNSTQIYVFKTYCLENKQAFFNRDSRFSTAIVGVFHQQSQQSKTKDDLNQNYLFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZB10</accession>
    <name>A0A5C6ZB10_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19950</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000052">
        <property type="protein sequence ID" value="TXD86554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="158" mass="17913" checksum="9C467F52644F8B84" modified="2019-11-13" version="1">MKMNNILNPIRLFAFLLIFTFITSCNFGNEKDNSKNSVGVSTSSEQETVSDSIIQFLIASAVKDFHSHNPPTAIDFRKIEIGYLLSSKNDTTFILCGEFLSEEEKEWNKFATMKTDGYEQHLGLQSLPYCQEANFVLTNNNLLAVELKNKLTAMKEQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBP1</accession>
    <name>A0A5C6ZBP1_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">UPF0056 membrane protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_18420</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the UPF0056 (MarC) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000031">
        <property type="protein sequence ID" value="TXD87033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002771">
        <property type="entry name" value="Multi_antbiot-R_MarC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33508">
        <property type="entry name" value="PTHR33508"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01914">
        <property type="entry name" value="MarC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00427">
        <property type="entry name" value="TIGR00427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="45"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="108"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="134"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD87033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="197" mass="21454" checksum="C88C85E6CAA18747" modified="2019-11-13" version="1">MDLQLNIKEIFTAFMILFAVIDIVGNIPIVIDLRKKAGHIESGKASIIAGVIMVIFLFLGQTILSLIGLGVNSFAVAGSFILFFIALEMILGITLYKEDENAAMTASVFPLAFPLIAGPGSLTTLLSLRAEYRIENIIVAVVLNVIIIFVVLKTSSRIERMIGQNGINIIRKVFGVILLAIAVKLFAYNIKALFELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBR4</accession>
    <name>A0A5C6ZBR4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Efflux RND transporter periplasmic adaptor subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_19220</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000038">
        <property type="protein sequence ID" value="TXD86786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HlyD_D23" evidence="3">
        <location>
            <begin position="88"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="170"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD86786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="396" mass="43725" checksum="7A00746BED6E8698" modified="2019-11-13" version="1">MKHIYQLFILAFILVSCSGGGKNSVENVMENGNIETVREKRAELVNQQQAINDKILLLDERIATLDTVKHIPLITTFTATPEVFNHVVELQGNVTTKALLTITPEYNGILTNVYVKEGQKVSKGQILGKIDDGGLSQQLAQLKIQSELAKTTYQRQKRLWDQNIGSEIQFLQAKSTYESQQEAVNQLNQQISKTTVKAPFNGTIDDVITEQGSVVAAGQTPLMRIVNLDDMYIETEVPERYVGNVVEGKDVTVDLPVLGKTLETKVRQASSFINPANRTFKVEVAVPNKDQSIKPNLTARLKINDYTNEAALLIPQSVISENADGEQYVYIVTGKNSEGIGTVKRMIVETGKVQGDVIEILKGLDAGAEIIKEGARSVRAGQLVEVINFKNQQDEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBT5</accession>
    <name>A0A5C6ZBT5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Aconitate hydratase</fullName>
            <shortName evidence="8">Aconitase</shortName>
            <ecNumber evidence="8">4.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">acnA</name>
        <name evidence="12" type="ORF">ESY86_19150</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>citrate = D-threo-isocitrate</text>
            <dbReference type="Rhea" id="RHEA:10336"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="EC" id="4.2.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <text evidence="8">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate from oxaloacetate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the aconitase/IPM isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.3" evidence="8"/>
    <dbReference type="EMBL" id="VORO01000037">
        <property type="protein sequence ID" value="TXD86811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00718"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003994">
        <property type="term" value="F:aconitate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047780">
        <property type="term" value="F:citrate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01580">
        <property type="entry name" value="AcnA_IRP_Swivel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044137">
        <property type="entry name" value="AcnA_IRP_Swivel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006249">
        <property type="entry name" value="Aconitase/IRP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018136">
        <property type="entry name" value="Aconitase_4Fe-4S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11670">
        <property type="entry name" value="PTHR11670"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00415">
        <property type="entry name" value="ACONITASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="SSF53732"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01341">
        <property type="entry name" value="aconitase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00450">
        <property type="entry name" value="ACONITASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5 8" id="KW-0408">Iron</keyword>
    <keyword evidence="6 8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aconitase" evidence="10">
        <location>
            <begin position="73"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="domain" description="Aconitase_C" evidence="11">
        <location>
            <begin position="732"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="415"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TXD86811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="936" mass="104713" checksum="13A9A0440EDC774B" modified="2019-11-13" version="1">MSKDPYNVKKSLEIQDKDFDYFSLTALKNQGHPIEKLPYSIRILLENVLRNFDDFAVTKAHIETLLHWKPDTTGEDIPFKPARVLMQDFTGVPAVVDIAALRAEVDRKGGDAQKINPMIPVDLIVDHSVQVDYFGTNYAYERNMEEEYKRNVERYTFLKWAKKAFKNFSVVPPGMGICHQVNLEYLAQGVTTRDGQIFPDTLVGTDSHTPMVNGIGVVGWGVGGIEAEAALLGQPIYFIMPQVVGLKLTGKLPLGSTATDLVLQIAHALRKHGVVGKFVEVFGPGLDHLSVPDRATIGNMSPEFGCTVTYFPIDDKTLDYMRKTNRAEDHVKLVETYCKTNMLWRENSEAITYSSVVELDVSKIEPTVAGPKRPQDKILLKDFKPKFIDLLQESFGRSYITMDDREEKESLARWKAEGGNQPVQPSKDDDKANNDREEVTIEKDDKNLRTVWINHGHDKFELSDGSVVIAAITSCTNTSNPFVMIGAGLVARKARERGIDVKPWVKTSFAPGSKVVTDYMKKADLMTDLEALDFHLVGYGCTSCIGNSGPLPPKIREAIDDYDLVVASVLSGNRNFEARVHPKVKMNFLMSPMLVVAYALAGRVDVDLINDPISYDRNREPVYLKDIWPSNDEINEIMAKVLTPGDYDKNYGEIFEGNEIWRNLEVPDDKLYQWDAKSSYIKEIPFFKDISEQPKNFQNIEAAKALLVLGDSITTDHISPAGAFSQDSAAGKYLVQQGVDANDFNSYGSRRGNDEVMVRGTFANVRIKNQLVDKEGGFTQHIPSGEEMTVYDAAQKYRENNTPLIVLAGKEYGSGSSRDWAAKGTFLLGIKSVLAESYERIHRSNLVGLGVLPLQYKEGDSAKSLGLTGKENFSITGIAEGLTPQKELHVVAENDKGDKTEFKVMARLDSEIEIDYYQNDGILQYVLRQFLDEEKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBX8</accession>
    <name>A0A5C6ZBX8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PLD phosphodiesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20290</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000063">
        <property type="protein sequence ID" value="TXD86407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PLD phosphodiesterase" evidence="1">
        <location>
            <begin position="212"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="267" mass="31277" checksum="3133CD3E81600D0F" modified="2019-11-13" version="1">MRLSDLTIESIKEFISGDNQLTPSLSGPNILKLFNKVGFKDVYKWDDGGMPNSLSRNGYVIEKLYEINGTKNLIKLLEIIFDPRHFANDQEKNIKIAVEKINPLLQQDGYRLEEFEARYKIIGSDLPDEIAIEIHFEEIQSQIIEQIRSAKFSIWLAVAWLTDKVLIRELYNKKREGLSVRIVVLDDDINQKYGIDYEKFFEAKRFKPTGIYKNIMHHKFCVIDLKTIIHGSYNWTNKARWNKETVSIDHSRELAEKFSTEFIELVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBY9</accession>
    <name>A0A5C6ZBY9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19925</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000052">
        <property type="protein sequence ID" value="TXD86549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="160" mass="17807" checksum="B2D46049ABE23CCC" modified="2019-11-13" version="1">MKKTFLFLAILMISFSCEKGSLEEQTSSYDLNFNFESQNSKTDSKSKSQVEQFNATIITDGDDIDIISDSLEISRAVNSETGKESYVIHLKNNSEQNTTAKTGGPVRELFDNVESGYFYDGNDCWIYGTWYHGDNGESLFVPAGAATQYLNNVCGWSNVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC38</accession>
    <name>A0A5C6ZC38_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_17950</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000028">
        <property type="protein sequence ID" value="TXD87198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="124" mass="14099" checksum="3B6D626757FB1910" modified="2019-11-13" version="1">MSTTTKNAYASYELIDGILHITYAKDVILDLPAALYVVKDRLKMHEGRYFPVLCDIRCIKEINKAARSYLSVEGSTLIKAVAFIVESPVSEMLSEFYLRTSKPPIPNESFNTIESALKFLNQYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC65</accession>
    <name>A0A5C6ZC65_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_18500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000032">
        <property type="protein sequence ID" value="TXD86986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="342" mass="40949" checksum="36BC426632CD5AE2" modified="2019-11-13" version="1">MTEREERIEKYRKFLIEEQEKELAENSELIKNFLQYCKKKKIIISEKNIEYIPTIGIVANYPNLVNLLNNKIQVDKEELVSFDVLEKEFKKQRFASGYLISDMFMAMANSYFRRGHYEKNAFAPRFIELYWNYSSSKNDKYISLDFDRVRINVDNRMLIELDTWYGAKFEENISDIEDGIVKLTPPLDLEKFDIKLFFNDVHSLNIKWYTKENIKVFQAEEFKQETEKIIKNGIEYYPAKYIHAEFDKLTGTFRHFDGAIHFYTENEYLQRRETDFNHNDKTGSQIKTLSQKLFKVNGEIEIKDWVELTSHFLTGNPLILEYFEGKLPDRIIEIISRLKNEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC92</accession>
    <name>A0A5C6ZC92_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19845</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000050">
        <property type="protein sequence ID" value="TXD86584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="159" mass="17647" checksum="F3E9540B2079778E" modified="2019-11-13" version="1">MVDLRKPINRNKTNGIKFGLVNCLISIGIGIFIIKTGFSPNGNVILITSTLAIFLCGLIFWNLLKVKTGSKAILAGVLTGLMSHPLTWFLLIIINNSCHFFHLNCSAEYIYSDGTITASNIIGEIFGGTVMSLLFFGYITIFTSSILSYLFFKYTEWQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCF1</accession>
    <name>A0A5C6ZCF1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_16140</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000021">
        <property type="protein sequence ID" value="TXD87680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023996">
        <property type="entry name" value="TonB-dep_OMP_SusC/RagA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04056">
        <property type="entry name" value="OMP_RagA_SusC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022756145" evidence="5">
        <location>
            <begin position="21"/>
            <end position="1008"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="7">
        <location>
            <begin position="114"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="6">
        <location>
            <begin position="411"/>
            <end position="1007"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD87680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1008" mass="111609" checksum="407F650448958D57" modified="2019-11-13" version="1">MKTKIVLFLMLLFGGFVMFAQDMAITGTVTTAQDDMPLPGVNVLVKGTSRGAYTDFDGKYTITASPGDVLQFSAIGLKSQSVTVANTTVINVALEEDAQALDEVVVIGYGTQKKIDLVGAITTVESEDIEKTPNSNVMQSLQGKVAGLQIVSNGAPGASPTVRLRGVNSFAGGDNPLYVVDGQWYDNIDFLDSSQIETISVLKDVSSIAIFGQRGVNGVIIVETKSGKLEQKASITYSGYTGVQNAQNVVKMANAEQFVTMAYESESAADIEFVENSIARFGRSRVNPNLPDVNTDWYKEILRPASITNHSIGVNGGSASTTYGVNASFFSQEGVLDMKNEYERFNIQSNIDVNVTNRLKVGTNSIFSNATQYNPENAAFFSAYFAVPTLPVFDFVNPEATSTPYSDAQFLDYRGSQNPFPVMDYNENQLKIRKILTSIYAEYQIVPDKLTFKTSYYHDYSTISERNVRLPYYISGNSNREQVETSIRRAESIYSFQQWDNTLTFTDSYGDHDLTVLAGSTFQDSQRNFFNATGSDVQGIALESSWYLNFADPTSFNDNVKEIGDRFYTLAYFGRLEYKFKDRYLLNATIRTEGDAKFPSEIWKTTAQFGLGWVISEEGFMEDNGIFDFLKLRGSWGQLANGALGGSAGSRTIDQVTLSIRDLLTNGIISSNNFTDLKREVLEETNIGISSRLFNNRLSLEADYYIRDTKDLVIPVQQPIVGNALLKNVGEMRNEGLEVALNWSESISDNWSYSIGGNIATLENSVTKINTVQGYLDTGSPEFLQRLIVGEPVNAFFGYEVAGVYQNDAQVANDPIAVDNNLVPGDLIYVDINNDGVIDDADRKVIGSYLPSFTYGGNFSVSYKNFDLSVAIAGQTGYQILNRKRGEVLFTNDTNIDAEYAINRWHGEGTSNTYPSSAGRRRAWNQKMSTFFVEDGDYFRIQNIQLAYTIPASSLIGKNMPETRFTFTAERPFTSFDYNGFTPEVPNGIDRQTYPIPAVYTVGVNIRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCR3</accession>
    <name>A0A5C6ZCR3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Endoribonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19025</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000036">
        <property type="protein sequence ID" value="TXD86849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="164" mass="19004" checksum="39803F31E0A7F68B" modified="2019-11-13" version="1">MIVKGYIQSTLDDMESLYNCHYSLKKDIYYSKLALIELCGWIEESFDSIIKLSIRNKLKSSSYKKYMKDTIKGTYGFQYNAHFRKMLIVAIGICEAEKLERKIDKSGKIQLLTSTLATLKEIRNENAHSFIKGTTTTIQTPSITKAQFLRIYPIIKELEREIRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDM8</accession>
    <name>A0A5C6ZDM8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphatidate cytidylyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="181"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="205"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="252"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="273" mass="31032" checksum="F0932C7F28F4F85C" modified="2019-11-13" version="1">MKELRTRALSGIIYISLLIVSLYWQHALIVLFFLFGMVCMGEFKKLIQLKSIWPYIVFAVLYAGFAYWESILTTSSGYAEASQILLVITIFVQLLLIKDLFSEKIIPLFETKRFIITTFYLSSAFVFLISIANFERNFTPLLLLGVFILVWVNDTFAFLVGKNFGKQKLFSSISPKKTVEGFLGGLFFACIASYFIARFTETLNFTHWLMLGIIVSVFGTLGDLIESKFKRQAKVKDSGVIMPGHGGLLDRLDSIIFAAAFVFLYLRLITYVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDP7</accession>
    <name>A0A5C6ZDP7_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ATP-dependent dethiobiotin synthetase BioD</fullName>
            <ecNumber evidence="5">6.3.3.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">DTB synthetase</fullName>
            <shortName evidence="5">DTBS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Dethiobiotin synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 6" type="primary">bioD</name>
        <name evidence="6" type="ORF">ESY86_13645</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes a mechanistically unusual reaction, the ATP-dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA, also called 7,8-diammoniononanoate) to form a ureido ring.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>(7R,8S)-7,8-diammoniononanoate + ATP + CO2 = (4R,5S)-dethiobiotin + ADP + 3 H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15805"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:149469"/>
            <dbReference type="ChEBI" id="CHEBI:149473"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.3.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; biotin biosynthesis; biotin from 7,8-diaminononanoate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the dethiobiotin synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.3.3" evidence="5"/>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00078">
        <property type="reaction ID" value="UER00161"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004141">
        <property type="term" value="F:dethiobiotin synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00336">
        <property type="entry name" value="BioD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004472">
        <property type="entry name" value="DTB_synth_BioD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43210">
        <property type="entry name" value="PTHR43210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006755">
        <property type="entry name" value="DTB_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00347">
        <property type="entry name" value="bioD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0093">Biotin biosynthesis</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="5">
        <location>
            <position position="32"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="12"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="43"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="99"/>
            <end position="102"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="158"/>
            <end position="159"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD88140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="204" mass="22405" checksum="C218239117EA71B9" modified="2019-11-13" version="1">MNTYFITGIGTDVGKTIVSAIITEALQADYWKPIQAGDLDNGDTQKVQRLISNKKSKFHPNAYALNTPMSPHAAADIDGVTIDLEQIKAPKTKNHLVIEGAGGLLVPINKTQTILDLIQPDYKVIVVSRHYLGSINHSLLTLDLLKQKGLDASIIFCGNENTSTEDIITSMSKVPVIGRIEEEPYFDQNVILEYAEKLKASITK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDT2</accession>
    <name>A0A5C6ZDT2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Aminotransferase class IV</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_18730</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000033">
        <property type="protein sequence ID" value="TXD86964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="SSF56752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="309" mass="34367" checksum="A992731EAF8ACDDC" modified="2019-11-13" version="1">MVHGTHNALEDDRNKDIKIYINGEYFSRNDAKISVFDSGYLVGDGIWEALRLHKGVLVFLEAHLERLWSSAASVGMTFPFTKAELTTIIHKVLDKNGMSDQVHVRIMITRGIKKTPSQDPRLTISGPNVVIIPEYKKASEESKQKGITLFTSTIRRGSPDYLDPRLNCHSKLHEVQALIQAIEAGADEALMLDVNGFVSTCNATNFFIVKNNEVLTSTGQYCMNGITRAKVIEVCKKHNIVCHEKNFSLFDVYGADEAFVTGSFGGITPVTKIDGRQIGSKPFGDMTQKLSGLYHDLIAETVANEKEYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE57</accession>
    <name>A0A5C6ZE57_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_16820</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000024">
        <property type="protein sequence ID" value="TXD87442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027791">
        <property type="entry name" value="Galactosyl_T_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02709">
        <property type="entry name" value="Glyco_transf_7C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="5"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_transf_7C" evidence="3">
        <location>
            <begin position="180"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD87442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="331" mass="38432" checksum="C986283A544F893D" modified="2019-11-13" version="1">MKFTLIICTYMRPKALLNLLNSVINQTLYPNQILVIDGSTDSETQQVLEKHRVQNLSYNKVDAQHRGLTKQRNFGISKVDQHSEVVCFLDDDTILAVDYFKHLLETYTQYPKALGVGGYITNEVQWHKTDGSKDFKRFYYDNWMRSEPLRFRIRKWFGLAPDTPPCYLPTFSHGRSVSFLPPSGKVYPVEQFMGGVASYRSSVFKTMQFSTYFEGYGLYEDTDFCLRLSKKGELYVNTSAQLAHYHDAEGRPNKYKYGKMVVRNGWYIWRVKYAKPNLAARLKWHLTAGLLMSLTLFGCFTARDKRAAIVESFGRFDGWLSLWIDKPEIEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEC3</accession>
    <name>A0A5C6ZEC3_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidoglycan glycosyltransferase</fullName>
            <ecNumber evidence="1">2.4.1.129</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">pbpC</name>
        <name evidence="11" type="ORF">ESY86_18210</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>[GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n)-di-trans,octa-cis-undecaprenyl diphosphate + beta-D-GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-di-trans,octa-cis-undecaprenyl diphosphate = [GlcNAc-(1-&gt;4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)](n+1)-di-trans-octa-cis-undecaprenyl diphosphate + di-trans,octa-cis-undecaprenyl diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23708"/>
            <dbReference type="Rhea" id="RHEA-COMP:9602"/>
            <dbReference type="Rhea" id="RHEA-COMP:9603"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:58405"/>
            <dbReference type="ChEBI" id="CHEBI:60033"/>
            <dbReference type="ChEBI" id="CHEBI:78435"/>
            <dbReference type="EC" id="2.4.1.129"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.129" evidence="1"/>
    <dbReference type="EMBL" id="VORO01000030">
        <property type="protein sequence ID" value="TXD87067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008955">
        <property type="term" value="F:peptidoglycan glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3810.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001264">
        <property type="entry name" value="Glyco_trans_51"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011815">
        <property type="entry name" value="PBP_1c"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009647">
        <property type="entry name" value="PBP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036950">
        <property type="entry name" value="PBP_transglycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06832">
        <property type="entry name" value="BiPBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00912">
        <property type="entry name" value="Transgly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02073">
        <property type="entry name" value="PBP_1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Transgly" evidence="9">
        <location>
            <begin position="63"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="8">
        <location>
            <begin position="300"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="domain" description="BiPBP_C" evidence="10">
        <location>
            <begin position="695"/>
            <end position="778"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF06832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD87067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="782" mass="88213" checksum="12D771B545AF072D" modified="2019-11-13" version="1">MKLINHIKKHKIKLAVLAVLLIAYGFCLPKQLFKDPTATVITSKNNQLLGAQIASDGQWRFPHNDSIPQKFSTCIVQFEDAYFYKHPGFNPISIFKALKGNLSSGEVKRGGSTLTQQVIRLSRKGKSRTYFEKIKEIILATRLELRDSKEAILTYYASNAPFGGNVVGLDAAAWRYFNRDASQLSWAESATLAVLPNAPSLIYPGKNQERLLNKRNRLLEKLLDNDIIDSLTYDLSLAEELPQKPYPLPQIAPHLLQKVALNQRGERVQTTIDKRLQEQANRVVENHYNLLKQNEIHNAAVMVMDVRTRKVLAYIGNTPTDNAHQKDVDVIDKPRSTGSILKPFLYAAMLDQGELLPNMLVADVPSQFGSYSPENYNKEFDGAVPASHALSRSLNVPAVRMLQQFGLDRFYHYLKALKLKDLNYNANHYGLSLILGGAESNLWDLCKSYGALSSTLNHYSENSSEYYSNEFVEPSFLASEKIDFGKKSADKTLFDAASIYLTFESLKEVNRPNGNESWEFFDDSKQIAWKTGTSFGFRDAWAIGTTKDYVVGVWVGNADGEGRPGLVGVQAAAPILFDVFDLLPNSDWFSKPYDEMQEVAICTKSGYRASPICDEIVTKHVQLSGLKTQACPYHILVHVDKTLSFQVNSSCENLGDIKHEAWFVLPPLMAYYYKTKNPFYKALPKLRMDCMGETSVVMDFIYPKNSNTIFLPKDFDGRTNELVLKIAHSKPETTVYWYVDDEYMGSTTAIHEFAILPKPGKHLITVVDDLGNERKRYVTISE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZED2</accession>
    <name>A0A5C6ZED2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_18035</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000029">
        <property type="protein sequence ID" value="TXD87128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="474"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="domain" description="AAA_16" evidence="2">
        <location>
            <begin position="20"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="656" mass="75155" checksum="65274F219AC1CA55" modified="2019-11-13" version="1">MKKYPFKFLDSYKREDRGIFFGRDEEISALYEMVFQSSVILIYGASGTGKTSLINCGLAGKFQPHDWLALMIRRGNNINKSLEKALEDAGGNSLDPVVGVNWSNEWSDDAEKSNKELSAVGKSINAVYQKSFRPIYLIFDQFEELFILGTRAEQDLFIKTVQDILQSQQPVKLIFSIREEYLGHLSHFEREVPQLLRKKLRIEPMNLEKVKQVIIGATAYNDSNISIKSGESDLVAEGIFDKIKGEEKSLTIQLPFLQVFLDKFYLKITGDESRSTEAEFNVATLNDMGEIGDVLIDFLEGQVAGISNKLKERYPVLVPDMIWRILSPFSTLEGTKDPISKQDLYERLPNLDRTLVDAVVGDFINSRILRYNDTNEMFEIAHDALAKPIAEKRSVEETAQLEIKRLIKSQVAVKEEGREFFTEKQLVFIEPYLEKFPISDEEREWISKSRSHVTKEKLKDIDRQYAEILKKRRITILSVAIVALLLLITTTVFFAIEARKEGIVAEQEKVKSQNAENNTKELLKLVMQGRGEQYVNQNDSLLMEQLRIEQTYPIDSLIVPRASVSPSNKGSENRNYMLWVDVPSFRKYEIKQVNYKLCSGFVDRLRVSNEPSSSFSIGYLGYGYCPIIDIDVILQTGDTIKKVFSFEDFFRENPLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEF4</accession>
    <name>A0A5C6ZEF4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Mrr_cat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_17725</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000028">
        <property type="protein sequence ID" value="TXD87155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007560">
        <property type="entry name" value="Restrct_endonuc_IV_Mrr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04471">
        <property type="entry name" value="Mrr_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mrr_cat" evidence="1">
        <location>
            <begin position="310"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="437" mass="49850" checksum="31919BEDF8B0B504" modified="2019-11-13" version="1">MGTKWAKECENQIATYFQYLVDSLRTGDKKTVTKLLNALHEVNEIALGYSAGIPSGRGIGPQQAKEIQSAFESSQAAQSGDIKDIADCALMIPGISRDKISDITANILKSQLVEYTQKQCDKYELPTKRVAVNNAFDHNTLQFTSYFAQLPVIGDHAKILLPISSVRQDPELSKSKYYRNFVLEFLRAEHQHAGDALSSVLKNGQVVVRIMDLKEKYPMNVDFLYDFSKNHPKILENYKAELRRTAIKKGKAQLVTNRKILNSIDRKVIMNSIQTGRKDAHQFHKISFDNLIHIFGKRTSNPTSEQVINESRKRIDIVFTNSDKNGFFHNLNTVHKLKCPKIIVECKNYGNELGNPEVDQINGRFNSKRGRFGILVCRTIKDRKALLSRCKDLINDNENYVIVLEDNDIHQLLELRDKNDESGIDNFLEKKMDELIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEH5</accession>
    <name>A0A5C6ZEH5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Mannose-6-phosphate isomerase</fullName>
            <ecNumber evidence="3">5.3.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_12995</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-mannose 6-phosphate = D-fructose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:12356"/>
            <dbReference type="ChEBI" id="CHEBI:58735"/>
            <dbReference type="ChEBI" id="CHEBI:61527"/>
            <dbReference type="EC" id="5.3.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="4">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the mannose-6-phosphate isomerase type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.8" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004476">
        <property type="term" value="F:mannose-6-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001250">
        <property type="entry name" value="Man6P_Isoase-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014628">
        <property type="entry name" value="Man6P_isomerase_Firm_short"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01238">
        <property type="entry name" value="PMI_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036894">
        <property type="entry name" value="PMI_Firm_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="active site" evidence="5">
        <location>
            <position position="200"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="105"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000757"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR036894-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR036894-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD88429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="323" mass="36570" checksum="3238F20A154CE1EA" modified="2019-11-13" version="1">MTPALYPIKFEPILKEKIWGGKKLKRILHKKSDRPNVGESWEISDVDGDVSVVANGMLKGQSLKQLLQDHGKEILGEHNFKTFGTKFPLLIKFIDAKADLSIQLHPNDELAAKRHNSFGKTEMWYVMQADQDAKLIVGFNQEMNQALYLKHLKNNTLIDILNVDPVKTGDSYFIDVGRVHAIGSGVLLAEIQQTSDITYRVYDWDRVDDQGNARELHNDLAIDAFDFDMPDDFRLSYASEANKSNDMVSCAYFKTSFVHVTQTLPKQNDKDSFFIYICVEGEAQIVSNQGTETIKSGETLFLPAAIKQYQLVSKNAKLLEVYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEP3</accession>
    <name>A0A5C6ZEP3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Anthranilate synthase component I family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_16385</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005801">
        <property type="entry name" value="ADC_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019999">
        <property type="entry name" value="Anth_synth_I-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006805">
        <property type="entry name" value="Anth_synth_I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015890">
        <property type="entry name" value="Chorismate_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236">
        <property type="entry name" value="PTHR11236"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04715">
        <property type="entry name" value="Anth_synt_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00425">
        <property type="entry name" value="Chorismate_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00095">
        <property type="entry name" value="ANTSNTHASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56322">
        <property type="entry name" value="SSF56322"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Anth_synt_I_N" evidence="2">
        <location>
            <begin position="16"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="Chorismate_bind" evidence="1">
        <location>
            <begin position="201"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="466" mass="53017" checksum="A75AA9AFF3293AE5" modified="2019-11-13" version="1">MKTFSLYTHYKKILADTITPVSIYLKIRDKYPNSILLESSDYHASDNSFSYICFNPIASIKVQNEVIEQRYPDGSTKTNNAQNISVTEEIHKFTKRFKVDSDNQFKFINNGIFGYTAYDAVKYFEDVEISKKPNSLEIPDIYYAVYQNIIAINHFKNEAYIFAHCFEAENNIDDILQLIKSKNFASYNFASDGDIESNLSDEAYKENVELAKQHCARGDVFQLVLSKKFSQQFKGDEFNVYRALRSINPSPYLFYFDYGNFKIFGSSPEAQLVVKDGLAEIHPIAGTFRRTGNDEQDAELAKKLAADDKENAEHVMLVDLARNDLSRHGSQVKVETYREAQFFSHVIHLVSKVTGKIHENTPTLQVVADTFPAGTLSGAPKHRAMQLIEAYEKTNRTYYGGAIGFMDFNGNYNHAIMIRTFLSKDHQLHWQAGAGIVSKSKPEDELQEVYNKLGALTKAIELAETI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZET1</accession>
    <name>A0A5C6ZET1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Redoxin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_14420</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13905">
        <property type="entry name" value="Thioredoxin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="236"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="379" mass="43698" checksum="7815540BB59F2631" modified="2019-11-13" version="1">MIRYIIFVVTILPIFSFAQFEIKGKILNLRDIENLNISLNVGMTINRNFNATIAKDSTFFITGKLDEPINGMLSFENGRESKSFKILLENESTYQVEVDLGSGDSLVDNSWYQIQTGSSYHNTWSEFYQVQHDLILKIKQVESDFENNTISKEILDKKLSNLSFEINQKFRDLAVQKPGNYAVAYILNGAPDLSLAYLPYYEQLEENVKNSYWGKKLNDTFKKFYSQGYQYEQKSSILGAQFKSIQGRGILENKIESFESNNLNSKLTLIDFWASWCAPCRLENFKLAVLNDYFDEGDFRIISFSLDNDLNKWKEATIEDDISWVNISDLKGVKSTAMADFQIKQLPRNILVNSKGEIIAVDKFGDSLMEYIEDFLKKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEY3</accession>
    <name>A0A5C6ZEY3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_12500</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="87" mass="10496" checksum="E6328FF5BD27B963" modified="2019-11-13" version="1">MKKRFLFISCEQAYLICDKAQYGEANLWERFELMLRLSWCKFARAYTKDNCALTAAIHSSKDKLLTEIEREEFRKNLERLIHKQPQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF62</accession>
    <name>A0A5C6ZF62_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Type IX secretion system protein PorQ</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">porQ</name>
        <name evidence="2" type="ORF">ESY86_17175</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000025">
        <property type="protein sequence ID" value="TXD87401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022812862" evidence="1">
        <location>
            <begin position="20"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="340" mass="38059" checksum="94A3D13A8329362D" modified="2019-11-13" version="1">MLKKITTICCLAFTGICAAQLGGESTYQFLNLIASPRQAALGGKVITNFDYDVTGGLFNPATINPEMDNQLALNYSSYLGGISYGSAAYAYTWDRHLQTFHFGMTYINYGSFDGYDLNGVSTGTFTGNEAALSVGYAYQIPFTDFYLGANLKMITSKLEQYNSIGIAADFGAIYINERLDFHAAITVRNLGTQILTYADLNEKLPLEVNLGLSQTLENMPLRWHLTFENLQQWPIGFSNPSRATTDLDGNQTQEKVGFFNEVLRHTIIGAELFPERGFNIRMAYNFRRAEELRILEQRNFSGLSFGLGIKLNKMRFSYTHARYSGASNANFFGIQIDLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF90</accession>
    <name>A0A5C6ZF90_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cysteine desulfurase</fullName>
            <ecNumber evidence="4">2.8.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">ESY86_13290</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[sulfur carrier]-H + L-cysteine = [sulfur carrier]-SH + L-alanine</text>
            <dbReference type="Rhea" id="RHEA:43892"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="EC" id="2.8.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 8">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.7" evidence="4"/>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031071">
        <property type="term" value="F:cysteine desulfurase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044571">
        <property type="term" value="P:[2Fe-2S] cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010240">
        <property type="entry name" value="Cys_deSase_IscS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016454">
        <property type="entry name" value="Cysteine_dSase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11601:SF34">
        <property type="entry name" value="PTHR11601:SF34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005572">
        <property type="entry name" value="NifS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotran_5" evidence="10">
        <location>
            <begin position="7"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="262"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD88278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="384" mass="42157" checksum="92A0C3FC0A694EAA" modified="2019-11-13" version="1">MKTKNKIYLDYNATTPVDKRVVDAMLPYFTEMFGNASSDHVFGWDAEEAVEFAREQVSNLVNCKPTEITFTSGATEAANLALFGFCKRNSSKGKHIITCKTEHKAILDTMQALENEGFQIRYLDVDTEGTIDLEELENAINAETILVCLMLANNETGLIHPMKQIEKIVHSKGVKLMSDITQAVGKIPVDLKELNLDLAIFSSHKLYGPKGVGALYINKKNKVEIDQTVFGGGQEKGMRPGTLNVPGIVGFGKATEIASEEMQEESIRISKLRNRLEALLEEIEDVLINSKNSDRLPNTTNVSFGNSDGNQLIRKLNSLAVSRGSACTSNLINPSHVLKAMGLSDEVALSSLRISLGRNTTLADINFAAEEIKNTVHQLKKAVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFG8</accession>
    <name>A0A5C6ZFG8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Enolase</fullName>
            <ecNumber evidence="8">4.2.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">2-phospho-D-glycerate hydro-lyase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">2-phosphoglycerate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">eno</name>
        <name evidence="13" type="ORF">ESY86_14975</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:10164"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="4.2.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="8">The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Cell surface</location>
        </subcellularLocation>
        <text evidence="8">Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the enolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.11" evidence="8"/>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00187"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000015">
        <property type="term" value="C:phosphopyruvate hydratase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004634">
        <property type="term" value="F:phosphopyruvate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03313">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00318">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000941">
        <property type="entry name" value="Enolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020810">
        <property type="entry name" value="Enolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020809">
        <property type="entry name" value="Enolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020811">
        <property type="entry name" value="Enolase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11902">
        <property type="entry name" value="PTHR11902"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00113">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03952">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001400">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00148">
        <property type="entry name" value="ENOLASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00002">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01192">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01193">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="SSF51604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="SSF54826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01060">
        <property type="entry name" value="eno"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00164">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="7 8 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Enolase_N" evidence="12">
        <location>
            <begin position="4"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="Enolase_C" evidence="11">
        <location>
            <begin position="138"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8 10">
        <location>
            <begin position="368"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8 9">
        <location>
            <position position="204"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8 9">
        <location>
            <position position="341"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="289"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="316"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent; in inhibited form" evidence="8">
        <location>
            <position position="341"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="392"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TXD87970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="431" mass="46308" checksum="15C00D5459726781" modified="2019-11-13" version="1">MSIIINIHARQIFDSRGNPTVEVDVVTENGIMGRAAVPSGASTGEHEAVELRDGGKAYMGKGVSKAVDNVNSIIAQELLGESIFEQNRIDQIMIDLDGTSNKSKLGANAILGVSLAVAKAAAGELGMPLYRYVGGVSANTLPVPMMNIINGGSHSDAPIAFQEFMIMPVKAKDFSHAMQMGTEIFHNLKKVLHDRGLSTAVGDEGGFAPTLEGGTEDALDTIKKAVENAGYKLGDDIMIALDCAAAEFYVDGAYDYTKFEGSNGKVRTSHEQADYLAELAAKYPIISIEDGMDENDWEGWKYLTDKIGDKVQLVGDDLFVTNVERLSRGIENGIANSILIKVNQIGTLSETIAAVTMAHNAGYTSVMSHRSGETEDNTIADLAVALNTGQIKTGSASRSDRMAKYNQLLRIEEELAEVAYFPQNNAFKIKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFI0</accession>
    <name>A0A5C6ZFI0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD-binding oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12755</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="1">
        <location>
            <begin position="16"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="370" mass="41393" checksum="10C34381EDAD3124" modified="2019-11-13" version="1">MNLSYWEIKSWLTNVDFTIIGSGIVGLNCAISLSRKYPKAKILILEKGMMPQGASTKNAGFACFGSLSELIDDLGTHSEAEVIELVEKRWEGLQLLREMLGDKTIGFKAFGGYELFAETENDLFETCLSQKEHINSLLHPIFKAEVFETRPNSFHFENIKDTYSFNAFEGQIDTGKLMEALLLKTASAGVKILNDCRVKSFAEDNAGVHVHTEHFDFKTKKLLIATNGFAQHFNISEVKPARAQVLITKPIENLSIKGTFHLEKGYYYFRNIDNRILLGGGRHLDFKTEETTAFGETEIIQNKLETLLKTVILPKQNFEIDHRWSGIMGVGNQKKAIVKQMSNNVFCGVRLGGMGIAIGSLIGKELAELT</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFP7</accession>
    <name>A0A5C6ZFP7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Universal stress protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_13145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Usp" evidence="1">
        <location>
            <begin position="7"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="277" mass="30902" checksum="FC144ADC4FACC6A9" modified="2019-11-13" version="1">MKNKAYKILVLSDLKDAAGITLKSTVCLAKMIGADIELLHVKKPTDVVKSENQLSAMRAINENYMATEKHIQKMIAPIVKEYGVDINFKFSFGNVPAEIEKHIQESQPDIIVLGKRKPRMIKFIGDGITQFVLNNYNGIIMLADDTNALAPDTELSLGVLNNEAQNLNIDFAEDLVSHCLKPFKCFQIIQNSNALDEKTAVSDQDLVTYVFQQGDNAIDSLSKYLSLNKVNLLFVDRTVNATRSNSNLIDPDIQSIMDSLNVSLLLSRETSRHENTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFR1</accession>
    <name>A0A5C6ZFR1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TlpA family protein disulfide reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_14430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13905">
        <property type="entry name" value="Thioredoxin_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="318"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="490" mass="58531" checksum="8788D04FCF162ADB" modified="2019-11-13" version="1">MKKSLLILLILVVCCKNETEDRKTLERKNPVANDYQTTSIYFIEKPTDTFHFENRISRLTSVINILNENGFQKEIILNDDENEFEYATIKDTFILTHNYRNYDLYFELKKGDSIRYYERDGFPFYTGTEEMLNQSNLYDYKRIKYLNKMPPYDFFSYYLSHKNLMKNNDTLRKNYVRELVTSNEKEDFFLDSLYSLNQITASKYRLQKDKLKYNFYNDLPFNDYKNFLIKDSLIDDLNRKDLIKYPFYKKFLDNYSAYTFDIKNLRQSNRLVRDHKSNFDSIEKSSLFSKQIKSFLLYSNLVEIGSNFSQTDFNNYFVKFRKQVNDSILLSSIKNKFLTNMSESKEEVKVVYFITKHNNKKTLAEIVNHNQGKLIYIDFWASWCAPCLAAMPASRELREKYIDKDIVFIYASIDKDFEEWEKAAMTENLSFNENNLLTVNYPNANFYKELNMKTIPRYLLYDKSGNLVSENAPGPNTKENIKLIEKFLLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFU5</accession>
    <name>A0A5C6ZFU5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 13 15">tRNA (guanine-N(1)-)-methyltransferase</fullName>
            <ecNumber evidence="6 13 15">2.1.1.228</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">M1G-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">tRNA [GM37] methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13 17" type="primary">trmD</name>
        <name evidence="17" type="ORF">ESY86_11025</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 13 15">Specifically methylates guanosine-37 in various tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13 15">
            <text>guanosine(37) in tRNA + S-adenosyl-L-methionine = H(+) + N(1)-methylguanosine(37) in tRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:36899"/>
            <dbReference type="Rhea" id="RHEA-COMP:10145"/>
            <dbReference type="Rhea" id="RHEA-COMP:10147"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73542"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="EC" id="2.1.1.228"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5 13 15">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 13 15">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13 15">Belongs to the RNA methyltransferase TrmD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.228" evidence="6 13 15"/>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052906">
        <property type="term" value="F:tRNA (guanine(37)-N(1))-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18080">
        <property type="entry name" value="TrmD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1270.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00605">
        <property type="entry name" value="TrmD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002649">
        <property type="entry name" value="tRNA_m1G_MeTrfase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023148">
        <property type="entry name" value="tRNA_m1G_MeTrfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016009">
        <property type="entry name" value="tRNA_MeTrfase_TRMD/TRM10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46417">
        <property type="entry name" value="PTHR46417"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01746">
        <property type="entry name" value="tRNA_m1G_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000386">
        <property type="entry name" value="tRNA_mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00088">
        <property type="entry name" value="trmD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13 15" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 13 15" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 13 14" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="10 13 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="12 13 15" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA_m1G_MT" evidence="16">
        <location>
            <begin position="23"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="13 14">
        <location>
            <begin position="132"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00014679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000386-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU003464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="TXD88766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="224" mass="25111" checksum="BC8BDD572F8F3FE8" modified="2019-11-13" version="1">MRIDIITVLPELLKSPFEASILKRAIEADLVSVHFHNLRDYATGGYKAIDDTQFGGGAGMVMMIEPIDKCITQLQSEREYDEIIYMTPDGERLNQSIANQVSLKENIIILCGHYKGVDQRVRDKFITREISIGDYVLSGGELGAAVLCDAIIRLIPGVLGNETSALTDSFQDGLLAPPIYTKPREYDGMKVPEVLFSGNFPKIETWREEQAYLRTKARRPDLLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFV3</accession>
    <name>A0A5C6ZFV3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF2914 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_11075</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022606">
        <property type="entry name" value="DUF2914"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11141">
        <property type="entry name" value="DUF2914"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2914" evidence="2">
        <location>
            <begin position="288"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="371" mass="43390" checksum="DC4CCAF46272FDEE" modified="2019-11-13" version="1">MKRTLVKFRNSDFRQFITRHQKYAPILFFIGGFIFDTLTLGRIDRIYDISVLCLHMTSLTITLYLFNIMEDGKLRNTIFERFEPYFPLAIQFFFGGLSSAYVVYFSRSVSLSKTITFFIILVLLLFANELLKKRISNKYLQFTVYFFISFTFFTFMLPVLFKEMNTAMFIISGLVSLGSTLTLIIFIYSRSQSTRLEINLAKLLGMVFIIYGTINVFYFFNMIPPVPLAMETGLVAHSIEIKNNKYEVSYERDEWYVFWRQHNSVFTHHPGENVYVFSSIFAPTDLKKAISHRWGWLNPDTNTWEIFDDIGFEMTGGRDNGFRGYTFKNNVKDGTWKVEVITEEGLVLGVIDFEIKTSASDPPIRMITRKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFV6</accession>
    <name>A0A5C6ZFV6_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Aspartate 1-decarboxylase</fullName>
            <ecNumber evidence="9">4.1.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Aspartate alpha-decarboxylase</fullName>
        </alternativeName>
        <component>
            <recommendedName>
                <fullName evidence="9">Aspartate 1-decarboxylase beta chain</fullName>
            </recommendedName>
        </component>
        <component>
            <recommendedName>
                <fullName evidence="9">Aspartate 1-decarboxylase alpha chain</fullName>
            </recommendedName>
        </component>
    </protein>
    <gene>
        <name evidence="9" type="primary">panD</name>
        <name evidence="14" type="ORF">ESY86_13740</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>H(+) + L-aspartate = beta-alanine + CO2</text>
            <dbReference type="Rhea" id="RHEA:19497"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:57966"/>
            <dbReference type="EC" id="4.1.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9 10">
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </cofactor>
        <text evidence="9 10">Binds 1 pyruvoyl group covalently per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="9">Cofactor biosynthesis; (R)-pantothenate biosynthesis; beta-alanine from L-aspartate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Heterooctamer of four alpha and four beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="9 12">Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the PanD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.11" evidence="9"/>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00028">
        <property type="reaction ID" value="UER00002"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004068">
        <property type="term" value="F:aspartate 1-decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006523">
        <property type="term" value="P:alanine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06919">
        <property type="entry name" value="Asp_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00446">
        <property type="entry name" value="PanD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003190">
        <property type="entry name" value="Asp_decarbox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21012">
        <property type="entry name" value="PTHR21012"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02261">
        <property type="entry name" value="Asp_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006246">
        <property type="entry name" value="Asp_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00223">
        <property type="entry name" value="panD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="1 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 9" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="6 9 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 9" id="KW-0566">Pantothenate biosynthesis</keyword>
    <keyword evidence="8 9 10" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9 10" id="KW-0704">Schiff base</keyword>
    <keyword evidence="5 9" id="KW-0865">Zymogen</keyword>
    <feature type="chain" id="PRO_5023561591" description="Aspartate 1-decarboxylase beta chain" evidence="9 13">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023561590" description="Aspartate 1-decarboxylase alpha chain" evidence="9 13">
        <location>
            <begin position="25"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9 11">
        <location>
            <begin position="73"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate; via pyruvic acid" evidence="9 10">
        <location>
            <position position="25"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="9 10">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9 11">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="modified residue" description="Pyruvic acid (Ser)" evidence="9 12">
        <location>
            <position position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR006246-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR006246-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR006246-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR006246-5"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TXD88157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="116" mass="12695" checksum="7A7660F0861541B0" modified="2019-11-13" version="1">MQIQVVKSKIHRVKCTGAELNYIGSITIDEDLMDAANIIQGEKVQIVNNDNGERLETYCIPGPRKSGEITLNGAAARKVAVGDTLILITYAFMDLEVAKTFKPSLVFPDEATNLLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG58</accession>
    <name>A0A5C6ZG58_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_15450</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="149" mass="16852" checksum="CB2FFCC2607832FD" modified="2019-11-13" version="1">MTYKTVMRDVVLEKSKEQTENDSISGTMSGMFKALQNQLSGLKYETKLFPDNTGNVDIEMLLKNDKADTTEKLFSGMAKMNGNVVLRGKVSPEGEVLSFYYKRAQNNLISMLFELPAKPAKVGDEWNLKVDMITMDQNFKADTYSKKTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-04-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG80</accession>
    <name>A0A5C6ZG80_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_10645</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039426">
        <property type="entry name" value="BtuB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30069">
        <property type="entry name" value="PTHR30069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0675">Receptor</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <keyword evidence="1 4" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023063230" evidence="5">
        <location>
            <begin position="18"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="7">
        <location>
            <begin position="125"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="6">
        <location>
            <begin position="352"/>
            <end position="770"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD88945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="787" mass="88256" checksum="9BDDAEEE2AF628AC" modified="2019-11-13" version="1">MAIQIRSCLFFIATVLAFGSLSGQVNTTIYGQVSDELGKPIIGASVFLEGTQLGVQSNLDGNYEISGVPPGSYNLIVSYLGYEPQTKFNIIVRSKGTPNYDFVLKESAQALNEVVISNANIITRPRETPLSTQTLSAVEIATYPGGNNDVVKVAQTLPGVSPSIGGFRNDLIIRGGAPNESVYYLDGMEIPNINHFATQGSAGGPQGLINVSFIDNVTLSTSAFNARYDNPLSGVLQFKQRNGNARELSGNFRLSASEAALTFEGPLFKKDAEESKTTFLASVRRSYLQFLFEVIGLPIRPNYWDYQFKINHEINAYNTITFLGLGSIDDFSIRPLEEFDIDQQASLDQTPFIEQRTNTMGLSWKNRFKSGKGFMQTTLSSNTLKNEFTRYEDPVNEQGVIFNNDARESETKLRHELTQFLGDWKLSSGFNLQYSDYTNLTTDVRNALTFDTAIDFAKYGLFANATRSFFNDRLDLSLGFRMDDDSFTQSETLLTTFSPRFSASYEFAEDWRLSGSVGRYFKLPPYTILGFRDANNELINQNVDYTQSDHLVLGLQHYFSPSSSISFEGFYKRYEDYPVSVRDGVSLANKGGGFEVLGSEPIETVGKGRSYGAELNFQQKLTDNFYGIFSYTFFYSEFTGFDTNTYLPSVWDSRHLISFVGGYKLKRDWELSSRYRFAGRTPFVPTDLDATLDNYPEVILDYSRLGDETLAVFSQLDVRIDKKYNFEKFALNFFIEVQNILFQDIPSPPEYVLNRDASGTIVQPERLISVGDDFGSPIPGIGIVVDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG94</accession>
    <name>A0A5C6ZG94_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_13410</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="3"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="39"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD88301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="222" mass="25003" checksum="177C68B39D491D3B" modified="2019-11-13" version="1">MLLELNNIFKWVNQGGNRVFLLKDLNLEVEEGEFISIMGPSGSGKSTLLNVIGMLDGFQEGEYKFLDESVHAMKEKNRSKLYKEYIGFVFQAYHLIDELTVYENIETPLLYKNIKSAERKALVADMLDRFNIVGKKDLFPAQLSGGQQQLVGIARALVAKPKLILADEPTGNLNSNQGEEIMQLFKELNQEGVTIIQATHSETNAAYGSRTLHLLDGRRDHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGC7</accession>
    <name>A0A5C6ZGC7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_13215</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022732201" evidence="1">
        <location>
            <begin position="23"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="353" mass="41423" checksum="E9887971D49D841A" modified="2019-11-13" version="1">MNKQIFSALVLFYFFFSTSSFAQTAADTTQTTKISKLFRSQRVVPIKMSYSRKEMKKETNDSSYITTNFEYQTSEGNWKSIGLQLRKRGNFRLKNCTFPPLKLKIKKDSAKGTIFKGNKRLKMVMPCSAQSGNNNKVVKEYMAYKFYEQLSPYHFKTRLLEIDYTDMKNKKPKNYKFMGFLIEDDKVVAKRYNGKVLNRNVHPLHQEVVCSVRHAFFQFMIGNTDYSAAYGHNVKLFFIDKNTVPVPYDFDMSGLVNARYAVVSQINNETLPMENVRQRLYRGFKQPNDVFQQVRQEYLGQKDAIYAIIEDCKPMFDDDSEYEKAKEYIQDFYQILINDAKFSKEIVKVARTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGD2</accession>
    <name>A0A5C6ZGD2_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cyanophycinase</fullName>
            <ecNumber evidence="4">3.4.15.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_13450</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Exopeptidase that catalyzes the hydrolytic cleavage of multi-L-arginyl-poly-L-aspartic acid (cyanophycin; a water-insoluble reserve polymer) into aspartate-arginine dipeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[L-4-(L-arginin-2-N-yl)aspartate](n) + H2O = [L-4-(L-arginin-2-N-yl)aspartate](n-1) + L-4-(L-arginin-2-N-yl)aspartate</text>
            <dbReference type="Rhea" id="RHEA:12845"/>
            <dbReference type="Rhea" id="RHEA-COMP:13728"/>
            <dbReference type="Rhea" id="RHEA-COMP:13734"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:137986"/>
            <dbReference type="ChEBI" id="CHEBI:137991"/>
            <dbReference type="EC" id="3.4.15.6"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase S51 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.15.6" evidence="4"/>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004180">
        <property type="term" value="F:carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044260">
        <property type="term" value="P:cellular macromolecule metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005320">
        <property type="entry name" value="Peptidase_S51"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011811">
        <property type="entry name" value="Peptidase_S51_cyanophycinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03575">
        <property type="entry name" value="Peptidase_S51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02069">
        <property type="entry name" value="cyanophycinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0720">Serine protease</keyword>
    <keyword evidence="8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023134583" description="Cyanophycinase" evidence="8">
        <location>
            <begin position="24"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD88341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="283" mass="30527" checksum="C0404005240C20A0" modified="2019-11-13" version="1">MILKNILCLVVMLIAGFQFSACAQESDAQGKLVIIGGGSRPAAMIDRIIKESGIDKEGYGIILPMSSVEPDSAVYYAKMQFTKVGINNVHGLQFAKGERLGSAKLDSIKKAKLIYISGGDQNRFMDIVAGTTAEKAIHEAYENGSLLAGTSAGAAVMSKMMITGNELKHPEYASTFRNIESENIELKTGLGMLNNVLIDQHFVKRSRYNRLISAVIEHPELMGIGIDESTAILVIGKSAEVIGESQVIVFENPDRSKTEKNGKLGAQGLALNIYLPGDSFTLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGD5</accession>
    <name>A0A5C6ZGD5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">T9SS type A sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Por_Secre_tail" evidence="1">
        <location>
            <begin position="201"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="269" mass="29461" checksum="D1188E769EA82A66" modified="2019-11-13" version="1">MADYWIVKLNGQGIVEWDTRLGGSLVDVPWDVELTTDGGYIVAGYSASTDGDVTGNHGGYDYWVVKIDAAGDLVWEKSLGGTDNDRAISISQTTDGGFILTGYSNSSDGDISENQGSYDGWTVKLDNDGNLQWEMSLGGSKSDNFRSIAQTSDGGYVMTGWINSNDSGVVVLYGDSDFWVVKFGAETLGLATNENNDDISVHPNPVSETLYISTKQQVEEVKLYDMLGKQIFNSNYRSQIDVSRFQSGVYVLKLITDQGQFTKRILINQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGF7</accession>
    <name>A0A5C6ZGF7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CsbD family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_11120</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0337 (CsbD) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008462">
        <property type="entry name" value="CsbD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026042">
        <property type="entry name" value="YjbJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036629">
        <property type="entry name" value="YjbJ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05532">
        <property type="entry name" value="CsbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039008">
        <property type="entry name" value="YjbJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69047">
        <property type="entry name" value="SSF69047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CsbD" evidence="2">
        <location>
            <begin position="4"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="61" mass="7266" checksum="A4AFD6F1AA790B0B" modified="2019-11-13" version="1">MNNDQFEGKWKQIKGDFKKKYGKITDDEYKEAEGDMDKLAGKMQEKYGKSKEDVKKEIDNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGL3</accession>
    <name>A0A5C6ZGL3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Site-specific integrase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_09425</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035386">
        <property type="entry name" value="Arm-DNA-bind_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025269">
        <property type="entry name" value="SAM-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17293">
        <property type="entry name" value="Arm-DNA-bind_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13102">
        <property type="entry name" value="Phage_int_SAM_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="3">
        <location>
            <begin position="222"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="414" mass="48703" checksum="777F45AE0F5F5182" modified="2019-11-13" version="1">MRTTKTFSIRFWADAQNANNNIALVYARLTVNQKRLSLSLKRRLPLDLWDAKSQRLRGNSSEAKEINQYFQEVRTRLFQIYQDLKFKNELITAQKIKSAYCGDNESSKTLIELINYHGNKIENTHAAGSIRNFVVTEGYIKKFMLADRKTSDVFLKQMDYKFICDFERFLHAYYPKGHKREMTHNTVMKHIQRLRKMVTLAYHLEWLDKDPFIRWKMTFEKKERDFLTTNELSNLETYDFPIERLERVRDLFLFSCYTGISYVDVKNLKPKHILEGMDGNNWIITHRQKTKTKVKVPLLDKAKLLLEKYENHPMALISETLFPILSNEKTNLYLKEIASAVGIRKNLTFHMARHTFATTVTLSNGVPIETVSKLLGHTKVATTQIYARVLEEKLSKDMIDLQKTLNAKDELKRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGM1</accession>
    <name>A0A5C6ZGM1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyltransferase family 4 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_09805</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="446" mass="51519" checksum="9FA051B079FC6B7E" modified="2019-11-13" version="1">MTNILYIAYQFPPLNVGGSARPARFVKHLSKFDINTTVVTLDPESYSNVYPHAKSDSNLLDDYKIDFSILKVPSKNLVERRANKVSNFIDIFFNKYKGNEHTYWQEDYHSIVDKWLETNSVEAIVVTAPPFSILPLAVATSKKHNIPLVVDLRDHWTLWVMAPYGTYYKYLASKVAENKVFRHAKKIIVTSKVTQQDLIDFHPNIAAHKFKYIPNGFETPIVYKDITFKPSEEIVIGYVGSFYYSPESRDLIMTPWWKKKAHRKLQYVPRKEDWLYRSPYFLFKNLDALFLTYPELKHIIKVKFAGTRPDWFDEMVSEFGLENNVEHLGWISQTESLAFQDSCDFLLATSAKVIGGRDYSIAGKTFEYFRMQKPILALVAEGAQKDMLEQSGMAHLIAIDNTTLAKEQLHTVFTSEHTLHPNKTFIDSFQIEKLTEALANEIKALE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGS1</accession>
    <name>A0A5C6ZGS1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_10150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="379" mass="43398" checksum="86CFE8ED374BC853" modified="2019-11-13" version="1">MKVLLVGEYNRSHKFIKEGLVALGHEALVVGLSDGFKKVDVDLEIKHKYSGWFLKKTRTALFKIFKIDLYSNSVKNQILKLKPKLSGYDIVQFISESSFICQPETEKAIFDLLNSWNGKSFLLSCGTDYPSVQYAMEKKFKYSILTPFFENRLAESNFSLGLKYITPAFKALHDHIYNQIDGVISSDLDYYIPLKDHPKHLGMIPHAINTDQIPFSELKIKDKIVIFHGINRNNYYKKGNDVFEAALELIKAKHSEKIEIIRVESVPYATYIKAFDAAHILLDQVFSYDQGYNALEAMAKGKVVFSGAEHEWLEYYGVPEDSIVINALPDAEAIAKKLEWLILNPEELLNISKNAREFVRKEHGHVTCAQQYLDKWQGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGV8</accession>
    <name>A0A5C6ZGV8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_15505</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="74" mass="8132" checksum="38637300C656943B" modified="2019-11-13" version="1">MKLNLLSCDAQRPDRRAIAKCIAEISSSMDEPLSNELTDILLEGDAVAIAVEDRNSASALRALRKLSIDYEIVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGW6</accession>
    <name>A0A5C6ZGW6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15555</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="91" mass="10653" checksum="0594D1CDCAB9638B" modified="2019-11-13" version="1" fragment="single">CRKSKTPCYQGNNLHHHNQLRAATKFSEIIRFLTWVSQRRKQEMIVYGGLTLLFQPFFKIALGREMWNIVDVIVGIGLIASLFMNRTKSQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGZ1</accession>
    <name>A0A5C6ZGZ1_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glycine--tRNA ligase</fullName>
            <ecNumber evidence="7">6.1.1.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Glycyl-tRNA synthetase</fullName>
            <shortName evidence="7">GlyRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">glyQS</name>
        <name evidence="9" type="ORF">ESY86_08440</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the attachment of glycine to tRNA(Gly).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly)</text>
            <dbReference type="Rhea" id="RHEA:16013"/>
            <dbReference type="Rhea" id="RHEA-COMP:9664"/>
            <dbReference type="Rhea" id="RHEA-COMP:9683"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78522"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.14"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.14" evidence="7"/>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004820">
        <property type="term" value="F:glycine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006426">
        <property type="term" value="P:glycyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00774">
        <property type="entry name" value="GlyRS-like_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00253_B">
        <property type="entry name" value="Gly_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027031">
        <property type="entry name" value="Gly-tRNA_synthase/POLG2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022961">
        <property type="entry name" value="Gly_tRNA_ligase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033731">
        <property type="entry name" value="GlyRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002315">
        <property type="entry name" value="tRNA-synt_gly"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10745">
        <property type="entry name" value="PTHR10745"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01043">
        <property type="entry name" value="TRNASYNTHGLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00389">
        <property type="entry name" value="glyS_dimeric"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="8">
        <location>
            <begin position="176"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="264"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="371"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="217"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="249"/>
            <end position="251"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="259"/>
            <end position="264"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="331"/>
            <end position="332"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="375"/>
            <end position="378"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD89405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="513" mass="59606" checksum="C0F344534E2018FA" modified="2019-11-13" version="1">MANDDQFKKVISHAKEYGYVFQSSEIYDGLSAVYDYAQNGAELKKNIRDYWWKAMVQMHDNIVGIDASIFMHPTTWKASGHVDAFNDPLIDNKDSKKRYRADVLVEDYCAKIEAKIDKEVAKAEKRFGDAFNKEEFVSTNPRVLRYTEDIETTLKRLGKSLSNEDLTDVKALIEELEIADPMTGSRNWTDVKQFNLMFGTKLGASAEHAMDLYLRPETAQGIFVNFSNVQKSGRMKIPFGIAQTGKAFRNEIVARQFIFRMREFEQMEMQFFIKPGTQMEWFEYWKEHRMKWHLSLGLGKENYRFHAHEKLAHYADAATDIEFKFPFGFKELEGIHSRTDFDLKQHEKHSGKKLQYFDHEENASYTPYVLETSIGLDRMFLAIFSNALEDETLEDGSTRTVLKLPAVLAPVKAAILPLVKKDGLPEIAKQIFEDLKWDFNVDYDEKDAVGRRYRRQDANGTPFCITVDHDTLEDNTVTIRHRDSMEQQRVKIEDLTGIIKKEVDVKHWLKKMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH18</accession>
    <name>A0A5C6ZH18_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Elongation factor G</fullName>
            <shortName evidence="6">EF-G</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">fusA</name>
        <name evidence="8" type="ORF">ESY86_14820</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16262">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01434">
        <property type="entry name" value="EFG_mtEFG1_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03713">
        <property type="entry name" value="EFG_mtEFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00054_B">
        <property type="entry name" value="EF_G_EF_2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009022">
        <property type="entry name" value="EFG_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035649">
        <property type="entry name" value="EFG_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004540">
        <property type="entry name" value="Transl_elong_EFG/EF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00484">
        <property type="entry name" value="EF-G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6 8" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="5 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="7">
        <location>
            <begin position="6"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="15"/>
            <end position="22"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="92"/>
            <end position="96"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="146"/>
            <end position="149"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD87939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="708" mass="78380" checksum="ACA92824814A1D33" modified="2019-11-13" version="1">MARDLKLTRNIGIAAHIDAGKTTTTERILFYTGVSHKIGEVHDGASTMDWMEQEAERGITITSAATTCDWTFPKENGEPTAEAKDYHFNIIDTPGHVDFTVEVNRSLRVLDGLVFLFSAVDGVEPQSETNWRLADNYKVPRIGFVNKMDRQGSNFLDVCQQVKDMLKSNAVPIVLNIGEEEDFRGIVDLVKNRAVVWHDENFGATFDVVDIPESMKEEVRKYRALLIEEVASYDENLLEKFMEDENSITEDEVHAALRAAVMDMAIIPMVCGSSFKNKGVQFLLDAVCRYLPSPMDRESVIGVNPDTDKEERRKPSVHEPFAALAFKIATDPFVGRLAFFRVYSGRLDAGSYILNNRSGKKERISRIYQMHSNKQIALDFIEAGDIGAAVGFKDIKTGDTMSDEKHPIVLESMDFPDPVIGIAVEPKTKADVDKLGMALSKLAEEDPTFTARTDESSGQTIISGMGELHLDIIVDRLRREFKVEVNQGQPQVEYKEAITRAADHREVYKKQSGGRGKFADIVFTIEPADEGVTGLQFVSAIKGGNVPKEFIPSIEKGFKMAMVNGPLAGYEVDSMKVTLKDGSYHDVDSDQLSFELAAKLGFKNSAKAAKAVIMEPIMKIEVITPEENMGDIVGDLNRRRGQMTSMGDRAGAKTVKATVPLSEMFGYVTTLRTLSSGRATSTMEFSHYAETPSNISEEVIKAAKGIEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH53</accession>
    <name>A0A5C6ZH53_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fumarate hydratase class II</fullName>
            <shortName evidence="2">Fumarase C</shortName>
            <ecNumber evidence="2">4.2.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Aerobic fumarase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Iron-independent fumarase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2 5" type="primary">fumC</name>
        <name evidence="5" type="ORF">ESY86_11955</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>(S)-malate = fumarate + H2O</text>
            <dbReference type="Rhea" id="RHEA:12460"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15589"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="EC" id="4.2.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism; tricarboxylic acid cycle; (S)-malate from fumarate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="2">There are 2 substrate-binding sites: the catalytic A site, and the non-catalytic B site that may play a role in the transfer of substrate or product between the active site and the solvent. Alternatively, the B site may bind allosteric effectors.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.2" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER01007"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045239">
        <property type="term" value="C:tricarboxylic acid cycle enzyme complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004333">
        <property type="term" value="F:fumarate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006106">
        <property type="term" value="P:fumarate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01362">
        <property type="entry name" value="Fumarase_classII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00743">
        <property type="entry name" value="FumaraseC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005677">
        <property type="entry name" value="Fum_hydII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018951">
        <property type="entry name" value="Fumarase_C_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11444">
        <property type="entry name" value="PTHR11444"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10415">
        <property type="entry name" value="FumaraseC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00979">
        <property type="entry name" value="fumC_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Lyase_1" evidence="3">
        <location>
            <begin position="11"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="FumaraseC_C" evidence="4">
        <location>
            <begin position="409"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="98"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="140"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="325"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="2">
        <location>
            <position position="189"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="319"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="320"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="2">
        <location>
            <position position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10415"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD88673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="465" mass="50347" checksum="83C3C65A961CCAB2" modified="2019-11-13" version="1">MDYRIEKDTMGEVQVPADKLWGAQTERSRNNFKIGPSASMPLEIIYGFAYLKKAAAYTNNELEVLSEEKRDMIAEVCDEILEGKHDDQFPLVIWQTGSGTQSNMNVNEVIANRAHQIAGKTIGEGEKTIQPNDDVNKSQSSNDTFPTGMHIAIYKKIVENTIHGVITLRNTLHNKSQEFKEIVKIGRTHLMDATPITLGQEFSGYVSQLDHGIKALENTLPHLAELALGGTAVGTGLNTPKGYSELVASYIAKFTGLPFVTAENKFEALAAHDALVETHGALKQLAVALNKIANDIRMLASGPRSGIGEITIPANEPGSSIMPGKVNPTQCEALTMVCAQVIGNDVAVTVGGTQGHYELNVFKPVMAANVLQSAQLIGDACLSFEAHCANGIAPNKEVIKQLLNNSLMLVTALNTKIGYYKAAEIANTAHKNGTTLKEEAINLGYVSAEDYDKWVNPKDMVGEIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH82</accession>
    <name>A0A5C6ZH82_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8 10">Uracil-DNA glycosylase</fullName>
            <shortName evidence="8">UDG</shortName>
            <ecNumber evidence="4 8 10">3.2.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ung</name>
        <name evidence="12" type="ORF">ESY86_11740</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 8 10">Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8 10">
            <text>Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil.</text>
            <dbReference type="EC" id="3.2.2.27"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8 10">Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.27" evidence="4 8 10"/>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88635.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004844">
        <property type="term" value="F:uracil DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd10027">
        <property type="entry name" value="UDG-F1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00148">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002043">
        <property type="entry name" value="UDG_fam1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018085">
        <property type="entry name" value="Ura-DNA_Glyclase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005122">
        <property type="entry name" value="Uracil-DNA_glycosylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11264">
        <property type="entry name" value="PTHR11264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03167">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00986">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="SSF52141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00628">
        <property type="entry name" value="ung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00130">
        <property type="entry name" value="U_DNA_GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8 10" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 8 10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="12" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6 8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDG" evidence="11">
        <location>
            <begin position="50"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8 9">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TXD88635.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="221" mass="24910" checksum="63C9B6FC8455845F" modified="2019-11-13" version="1">MIPKIAPSWQAELKTEFEKPYFEQLSEFVKSEYDAHPCFPPENEIYNAFNHCAFEAIKVVIIGQDPYHGLGQANGLCFSVHDGMKHPPSLINIFKEIEADLKVPYPKSGNLERWANQGVLLLNATLTVKAHQAGSHQNRGWERFTDTVIKTISDKKEQVVFLLWGGFAKKKTKLIDTTKHPVLSSGHPSPLSANRGYWFGNGHFGKTNAFLNDFGLSPINW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHE3</accession>
    <name>A0A5C6ZHE3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">1-acyl-sn-glycerol-3-phosphate acyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_07285</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="domain" description="PlsC" evidence="2">
        <location>
            <begin position="76"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="245" mass="28173" checksum="A1FB4B1118CACE8E" modified="2019-11-13" version="1">MRKLLAYPLTVIYLICFGITILVFHPIQLFCFKVFGYQAHKKSVDALQFFLIRCLTILGTRITWKNDFELPIDKPLLIVSNHQSMYDISPIMWNLRRHHVKFVAKKELGKGIPSISQNLRDGGSVLIDRNNPRQSLPAMLQFGEYIEKTKRAAVIFPEGTRSKDGYPKPFRMRGLELLIKKVPSAVIVPITINNSWKMLRYGKFPMGIGNHITFTIHKPIEIAIFTDKKALLERVKSTIVNAIEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHF2</accession>
    <name>A0A5C6ZHF2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">SCO family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_07365</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SCO1/2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02968">
        <property type="entry name" value="SCO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003782">
        <property type="entry name" value="SCO1/SenC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12151">
        <property type="entry name" value="PTHR12151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02630">
        <property type="entry name" value="SCO1-SenC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0186">Copper</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="56"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD89598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="222" mass="25511" checksum="AFDF19DD1633A5D4" modified="2019-11-13" version="1">MLSYIKKFKLFFISLAILSIIIMAIIYNILNVEQPLPVYQPVRIDASLVDSTIQNKRKYHSIANFKLINQNGDTITEADYKDKIYVADFFFTTCQTICPIMTDQMYRVQEAILEDDEVKLLSHSVTPEIDSVAQLKRYAIEKGVNDAKWNLVTGDRKQIYDLARKSYLVVKDDGLQDYGMIHTENFALIDKDKQIRGMYDGTSKASVDSLLVAIKKLKKSYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHG5</accession>
    <name>A0A5C6ZHG5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GIY-YIG nuclease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07390</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035901">
        <property type="entry name" value="GIY-YIG_endonuc_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01541">
        <property type="entry name" value="GIY-YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82771">
        <property type="entry name" value="SSF82771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GIY-YIG" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="74" mass="9028" checksum="752C13608EF5B752" modified="2019-11-13" version="1">MNHRVYILYSEKLDRFYVGYTSNLDLRLIFHQNPEQRKYTHNAKDWALYHKIDCSSKRQGLSIETHIKRMKSKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHH9</accession>
    <name>A0A5C6ZHH9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">SDR family oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_14540</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="272" mass="29402" checksum="AE71BFF260A15C45" modified="2019-11-13" version="1">MQKPNQRLINQTCIVTGGSSGIGSAVAKAIASEGANVVINYNSSKASAEELAHEISKDKRAGDVITCQADVSQEQDVQRLFKTSKDQFKHIDICVSNAGIQKDSPLHAMRLADWNKVIGVNLTGQFLCARAALNEFMNTGIRKDVSRSAGKIIHMSSVHEVIPWAGHANYAASKGGIAMLMQSICQGYAQYKIRCNSIAPGAIKTPINKEVWQDEAKMKKLLKLIPYDEIGEPSEIGSVASWLASDESEYINGTTIYVDGGMTCYPGFTTNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHP4</accession>
    <name>A0A5C6ZHP4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SPFH domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_13025</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="domain" description="PHB" evidence="2">
        <location>
            <begin position="50"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="286" mass="31763" checksum="2C96F7B433BECB31" modified="2019-11-13" version="1">MKAEKIIVPANGYLMLTVNLLLFFGSIAAMIMLESPFFVIATISALVIAPGFIMVQPNGSRVLLLFGEYVGSVKQNGFYWVNPFYTKKKISLRASNFDSERLKVNDKLGNPIMISTILVWRVKNTYKAAFDVDNYNDFVHVQTDAAVRKLASMYPYDNFADEGLDEDITLRSSVNEVSEALEKEIDERLTIAGIEVLEARIGYLAYANEIANAMLKRQQATAIVAARHKIVEGAVSMVEMALDELSKKQIVHLDDERKAAMVSNLMVILCGDKEASPVLNTGTLSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHR7</accession>
    <name>A0A5C6ZHR7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_14025</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="16"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="63" mass="6438" checksum="5998A8120C9A7B48" modified="2019-11-13" version="1">MESFGRTAKFIKFQISSSTSTSTSSSSSSSSSSSTSTSTSSSSSSSSSSSSISISSSFRFNLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHT7</accession>
    <name>A0A5C6ZHT7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015168">
        <property type="entry name" value="SsuA/THI5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09084">
        <property type="entry name" value="NMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NMT1" evidence="1">
        <location>
            <begin position="17"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="284" mass="32181" checksum="07AA3944E4390676" modified="2019-11-13" version="1">MRTIKIGGVPEHFNLAWYLTLKNGAYKEKGINLRWKDYFGGTGEMSKALRDGEIDMAVILTEGIIKDIIEGNPSKIVQTFVQSPLIWGIHVAHDSKYKSIEELKGSKAAISRYGSGSHLMAYINAENQGWDLEKDLDFEIIDDLNGAVDGLTKGKADYFMWEKFTTKPLVDNGSFRRVGNCPTPWPCFVIAVSDAFIKSDPEDIASILEIINTCTSGFKDIEQIDEIIAQRYDQKLEDVQEWLSLTEWSQQVIDDNAIDKIQDKLLMLDIISKKLPYDQLIHKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI37</accession>
    <name>A0A5C6ZI37_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF1572 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_11425</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011466">
        <property type="entry name" value="DUF1572"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07609">
        <property type="entry name" value="DUF1572"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="184" mass="21178" checksum="F5876EC8A7F6F773" modified="2019-11-13" version="1">MSNSYLNSVTKQFEYYKMLGDKTLEVLTIDELKLEMVADCNSAAIIVKHLCGNMLSRWTHFLTEDGEKSWRERDAEFIASAETKVQIINQWNRGWTCLFGALHTLQPKDLEQLIYIRNEGHTVTEAINSQLAHYAYHVGQMVFLGKLIKAEAWQSLSIPKGKSATYNQNKFSQDKARKHFTDDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI54</accession>
    <name>A0A5C6ZI54_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Anthranilate synthase component I family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_06345</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005801">
        <property type="entry name" value="ADC_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019999">
        <property type="entry name" value="Anth_synth_I-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015890">
        <property type="entry name" value="Chorismate_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236">
        <property type="entry name" value="PTHR11236"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00425">
        <property type="entry name" value="Chorismate_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00095">
        <property type="entry name" value="ANTSNTHASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56322">
        <property type="entry name" value="SSF56322"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chorismate_bind" evidence="2">
        <location>
            <begin position="169"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="253"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="435" mass="49945" checksum="037E33D0DA212D08" modified="2019-11-13" version="1">MRKTHFEHIANPEQFKNKLLQWSQQFDELLWLDSNDYKHSYPSYDAVLAAEAFTVLQTDSHNAFEQLKDYQTLTKDWIFGYLSYDLKNDVERLSSQNHDGLTFPELFFFQPKKLFLLKGNALEIQYLNLVSDEITQDLEQILAMESQSFDKTEMPSEVLPITIKPRISKDAYLEKATQMLTHIHRGNIYEANFCQEFYAEGSKIQAFEIFKKLNAISKPPFACYLKNHDQFLLSASPERYLKKEGDRIISQPIKGTAKRASNPSEDELLKQKLSEDQKERSENIMIVDLVRNDLSKTAKKGSVNVVELCKIHSFEQVHQMISTVTSTVKASVHPVDILKTTFPMGSMTGAPKISAMQLIEEFEASKRGLYSGAVGYFSPENDFDFNVVIRSILYNETKQYVSYSVGSAITSKSEPLKEYEECMLKAKAMREVLES</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI72</accession>
    <name>A0A5C6ZI72_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06755</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="22"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="306" mass="36187" checksum="C8E2C0B3B09B1A97" modified="2019-11-13" version="1">MQQDTENYYLIFESWSMDPNQWSMLIDSVAMLLAIFGVMIAFFLYKKQRSDNAKDAFEFFQSSLPELKQSIEKAAVDLKEFNQSLDLDNFVNPILSAALNDKFLSKISLVHLNRFYRNNRKNKLSNFKQLLIDSNFFGNYHSYITKEINYFRSNYLKKKSTYSQWQLLRSNQFFSTIANESDSRAYKEYYLNWVANFNLDLSDFEFIDQADPARVERRQVFVYDQIKELAQDSLPFIEFSKSANEVNILANEIVSAYKEMTEMKAKIKRVLDKDISRFETVLSNMNNLLEHEYDAKFIRNKDIQSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIW4</accession>
    <name>A0A5C6ZIW4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="12">HlyC/CorC family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">ESY86_09260</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04590">
        <property type="entry name" value="CBS_pair_CorC_HlyC_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002550">
        <property type="entry name" value="CNNM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044751">
        <property type="entry name" value="Ion_transp-like_CBS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005170">
        <property type="entry name" value="Transptr-assoc_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03471">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01595">
        <property type="entry name" value="DUF21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01091">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51846">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0129">CBS domain</keyword>
    <keyword evidence="6 8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="57"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="104"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="134"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="CNNM transmembrane" evidence="11">
        <location>
            <begin position="1"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="10">
        <location>
            <begin position="282"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TXD89226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="429" mass="48798" checksum="473BB078F32CC5A8" modified="2019-11-13" version="1">MDLSILIIILMLLLSAFFSGMEIAYISSNKIHIEIEKKQGDFLASILTKLTAKPSKFIATMLIGNNIALVIYGFLMGDVLVAWFQSMLPSQYPMVHYLLYDFSLLSQTIISTIVILITAEFLPKVFFQIYANSFLKIFAFPAYLFYLLFWFMSSFIMWISNSILRRFFKTEGDNVQLAMTKIELGNYISEQMESVEEHDEVDSEIQIFQNALEFSEVKAREVMVPRTEIVAVEVSESLKTISNLFIESGLSKILVYKENIDDILGYVHSFELFKKPKSLKAITMPVVFVPATMLVKDVLSILTKKRKSMAVVIDEYGGTAGIMTIEDIVEELFGEIEDEHDSVALIEEKLGVHHFKFSARLEVDYINETYKLNLPESENYETLGGLIVHATEGIPQVNDTVIMATYKFKILEVSSTKIDLLELQVIGED</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ57</accession>
    <name>A0A5C6ZJ57_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_06165</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023071816" evidence="2">
        <location>
            <begin position="21"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="383" mass="43520" checksum="7004BC05223FAB89" modified="2019-11-13" version="1">MKNLALLITAMFLMGTSVNATTTNSSNSNTSNTFVRAYGKSFIFVEGGVEFSIFADGQFDFYMPNYGPNVNAGFRNQNVSISFNSGYDYNPYVQYDDYGAIIQIENVPIYYDHYGRIVRAGDVNINYNRYGNISRLGGLYVHYNSYRHFSHYTGYINVYNRSYVYRPWHHYYTVPAASYCIVNRRPYRRHYVPTRYTFYRPYNNNYRQPVPVNSRRGAVATAGRRTSSISNRYNQEATPRRANANATRSRRAAVQNRAVESQNNSRRSNSNLSTSRSSNDRAQRASTRKSAVNTEVRNTSRTDNRSTNTTARASRSIVKKSRLNNQSNDVRTSQRLRKPSSANSRIATESRNIRSSNAVANPSASSRSASARTQSTSGSRSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ63</accession>
    <name>A0A5C6ZJ63_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2-amino-3-ketobutyrate coenzyme A ligase</fullName>
            <shortName evidence="1">AKB ligase</shortName>
            <ecNumber evidence="1">2.3.1.29</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Glycine acetyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1 3" type="primary">kbl</name>
        <name evidence="3" type="ORF">ESY86_08100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetyl-CoA + glycine = (2S)-2-amino-3-oxobutanoate + CoA</text>
            <dbReference type="Rhea" id="RHEA:20736"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:78948"/>
            <dbReference type="EC" id="2.3.1.29"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
        <text evidence="1">Binds 1 pyridoxal phosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid degradation; L-threonine degradation via oxydo-reductase pathway; glycine from L-threonine: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.29" evidence="1"/>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00046">
        <property type="reaction ID" value="UER00506"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008890">
        <property type="term" value="F:glycine C-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019518">
        <property type="term" value="P:L-threonine catabolic process to glycine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00985">
        <property type="entry name" value="2am3keto_CoA_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011282">
        <property type="entry name" value="2am3keto_CoA_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01822">
        <property type="entry name" value="2am3keto_CoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="1" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="2">
        <location>
            <begin position="43"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="1">
        <location>
            <begin position="111"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="1">
        <location>
            <begin position="241"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding; shared with dimeric partner" evidence="1">
        <location>
            <begin position="274"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="368"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="1">
        <location>
            <position position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="397" mass="43384" checksum="A7040D97621FCD39" modified="2019-11-13" version="1">MYGSIKQHLQNEIESIKEDGLFKEERIITSPQGAEITLSTGQTVLNFCANNYLGLSSHPDVVQAAKDAMDTHGFGMSSVRFICGTQDIHKELEQKISDFYSMEDTILYAACFDANAGIFEPLLGKEDAIISDALNHASIIDGVRLCKAARYRYKNSDMADLEQQLIAANENGARHKLIVTDGVFSMDGLVAPLDKICDLADKYDAMVMIDECHATGFIGATGRGTLEEKGVMGRVDIITGTLGKAMGGAMGGYTTAKKEIIELLRQRSRPYLFSNSLAPAIVGASIKVFDMLSNDTKLRDTLQENTAYFKKGLKAAGFDIIDGDSAIVPVMLYDAKLSQSMAKLLLQEGIYVIGFFFPVVPREKARIRVQLSAAHTKTHLDKAITAFIKVGKTLDII</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ87</accession>
    <name>A0A5C6ZJ87_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Adenine deaminase</fullName>
            <shortName evidence="5">Adenase</shortName>
            <shortName evidence="5">Adenine aminase</shortName>
            <ecNumber evidence="3 5">3.5.4.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 8" type="primary">ade</name>
        <name evidence="8" type="ORF">ESY86_06335</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>adenine + H(+) + H2O = hypoxanthine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:23688"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:17368"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.2" evidence="3 5"/>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000034">
        <property type="term" value="F:adenine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006146">
        <property type="term" value="P:adenine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01295">
        <property type="entry name" value="AdeC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01518">
        <property type="entry name" value="Adenine_deamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006679">
        <property type="entry name" value="Adenine_deam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026912">
        <property type="entry name" value="Adenine_deam_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11113:SF2">
        <property type="entry name" value="PTHR11113:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13382">
        <property type="entry name" value="Adenine_deam_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01178">
        <property type="entry name" value="ade"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="6">
        <location>
            <begin position="40"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="Adenine_deam_C" evidence="7">
        <location>
            <begin position="367"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD89819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="547" mass="59768" checksum="125821AD1F2B7331" modified="2019-11-13" version="1">MKIKGNIVDIKNRRIYKGEVSIIEGKITAIQAQDHDVENYIMPGFIDAHIHIESSMLVPSEFARIAVTHGTVATVSDPHEIANVLGIEGVNFMIENGKQSPFKFNFGAPSCVPATTFESAGAVIDSEGIKELMANPDIKYLAELMNYPGVLFDDPEVLKKIAWAKHYQKPVDGHAPGVLGDDITKYINAGISTDHECFTYEEGLEKLNKGMKILIREGSAAKNFEALIDLLPEHFENIMFCSDDKHPDDLMIGHINTLCARAVAKGMDVFQVLQAACVNPVKHYNLELGQLEIGDAADFIVVENLTDFKVLETYIDGHLVSEHGVSKLKSLPFENLNNFNTSEKEVSAFRLPSEAKHIRVIEAMEGQLVTNQLIEKTTIKNGNLISNTATDVLKMAVVNRYNDDAPALGFIKNFGLKEGAIASSVGHDSHNIVAVGVSDEMLCKAVNLIIKNKGGICAVNSSEDLSAEKMEKIVPLPVAGIMSDKDGATIGRQYADLDRMAKQLGSSLNAPYMTLSFMALLVIPSLKLSDKGLFDGKAFEFVSLEVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJD9</accession>
    <name>A0A5C6ZJD9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_06825</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. UvrD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013986">
        <property type="entry name" value="DExx_box_DNA_helicase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014017">
        <property type="entry name" value="DNA_helicase_UvrD-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000212">
        <property type="entry name" value="DNA_helicase_UvrD/REP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014016">
        <property type="entry name" value="UvrD-like_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070">
        <property type="entry name" value="PTHR11070"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00580">
        <property type="entry name" value="UvrD-helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13361">
        <property type="entry name" value="UvrD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51198">
        <property type="entry name" value="UVRD_HELICASE_ATP_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51217">
        <property type="entry name" value="UVRD_HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD-like helicase ATP-binding" evidence="7">
        <location>
            <begin position="4"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="UvrD-like helicase C-terminal" evidence="8">
        <location>
            <begin position="297"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="25"/>
            <end position="32"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD89906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="678" mass="77067" checksum="71612E67C9D1398F" modified="2019-11-13" version="1">MENHKLNEKQKKAVGYEGKHLLVLAGAGTGKTRCIVGRAAYLIEQGIAPEKIQILTFTKRSASEIVERVKASLTNNQAQSLNGSTFHSWCNQLIVRYPNLFGAAGYTVIDPDDQLSVMKMVCGDQIIEYKGIRIKPQQLIDIYSYGRNTRQNLSNAIREKVYKGKTDAETTDEIDIIRSRVEVLLKAYQTKKGEGRYIDYDDLLLVVANRLRNDAEARDILSHQLKHLLIDEFQDTNPLQWYLLEPFLEIAKFYCVGDDAQSIYSFRGADYKNVHLFKQRVPESEILILDKNYRSTQEILDVSNWLIAQSPLDYDKELQASRGSGMTPKLVNVASQWEEANFIAENILENFTENNKQFADHLILSKSTYYTKPLQAVFIQKKIPYVTYGGRKFMEAAHIKDVISALRVVNNHFDEIGWMRFLTFWDGIGEIKAGKYISQLVAFEDPLGCAQNLADVIGGQEGETIADIYNTIYRNAGNVKQALQETYSKMEQALAFKYRKDWEEKRKSDFPVLEMLGDNYASIGQMISEGILENAKQLNGNPVLEGSQISDSEIKDHVVISTVHSAKGLEADVCYVLNVSPKVYPSAWNLDSEEKVEEDRRVLYVALTRAKNELYITRDTNSINTVNKTKNAGFSSKYFLEELPNQLTEQLINPYSLIKPRDISKPNSIDLSFGMDFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJH8</accession>
    <name>A0A5C6ZJH8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptide-methionine (R)-S-oxide reductase</fullName>
            <ecNumber evidence="2">1.8.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">msrB</name>
        <name evidence="5" type="ORF">ESY86_03580</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[thioredoxin]-disulfide + H2O + L-methionyl-[protein] = [thioredoxin]-dithiol + L-methionyl-(R)-S-oxide-[protein]</text>
            <dbReference type="Rhea" id="RHEA:24164"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12314"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:45764"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.4.12"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.12" evidence="2"/>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033743">
        <property type="term" value="F:peptide-methionine (R)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030091">
        <property type="term" value="P:protein repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028427">
        <property type="entry name" value="Met_Sox_Rdtase_MsrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002579">
        <property type="entry name" value="Met_Sox_Rdtase_MsrB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011057">
        <property type="entry name" value="Mss4-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10173">
        <property type="entry name" value="PTHR10173"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01641">
        <property type="entry name" value="SelR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51316">
        <property type="entry name" value="SSF51316"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00357">
        <property type="entry name" value="TIGR00357"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51790">
        <property type="entry name" value="MSRB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MsrB" evidence="4">
        <location>
            <begin position="26"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="153" mass="17225" checksum="570D37DFDE4CC72F" modified="2019-11-13" version="1">MLTWKDVINYSVKGNPEPDRRVEKSDSEWREELTPEQFKIARQKGTEAPGTGALCSIHDEGQYNCVCCNTSLFDSTIKFESSSGWPSFTQPITKNAIKYEKDTKFGMVRVEVMCNVCDAHLGHVFPDGPEPNGLRYCINSESMVMDKSVKPAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJP0</accession>
    <name>A0A5C6ZJP0_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Type I site-specific deoxyribonuclease</fullName>
            <ecNumber evidence="3">3.1.21.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">ESY86_11545</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Endonucleolytic cleavage of DNA to give random double-stranded fragments with terminal 5'-phosphates, ATP is simultaneously hydrolyzed.</text>
            <dbReference type="EC" id="3.1.21.3"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HsdR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.21.3" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009035">
        <property type="term" value="F:type I site-specific deoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007409">
        <property type="entry name" value="Restrct_endonuc_type1_HsdR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040980">
        <property type="entry name" value="SWI2_SNF2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04313">
        <property type="entry name" value="HSDR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18766">
        <property type="entry name" value="SWI2_SNF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 13" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0680">Restriction system</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="12">
        <location>
            <begin position="311"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="888"/>
            <end position="910"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012654"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TXD88860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1015" mass="116099" checksum="E79E1DEC9807F2A9" modified="2019-11-13" version="1">MQSKTNEQALEATIEKQLTGTTLEAIKAEGLTIDGVNESGEMYPAGNGYFIGQAQNFNTQFAIDEAFFWQFLETTQKVELEKIKRQSDWKLKILNRFDRMVKKYGILHLLKKGLGVDDAHFTLFYVLPLASSSKAVKERFEQNSFSVTRQLRYSADNPREEIDMVLFVNGLPLVTMELKNHWTGQNAKVHGQQQYKTQRDTNQPLLQFARSIVHFAVDTDEAYMTTKLNGRDTFFLPFNKGNNHGKGNPPNPFGHKTAYLWEEVFTRKSLANIIQHFVRMDGSKKEALNSRTLFFPRYHQMNVVRDILGHASKNGVGQTYLIQHSAGSGKSNSITWAAYQLIETYPEQENTPGSKGIDQPLFDSVIVVTDRRLLDKQLRENIKEFSEVKNIVSPAYSSKELRESLEQGKKIIITTIQKFPFIIDGMADLSDKRFAVIIDEAHSSQSGTAHDKMNQAMGQQADPDEVDVQDKIILAMQARKMRGNASYMAFTATPKAITLEKFGMAEEDGSFKPFHLYSMKQAIEEGFILDVLANYTTLKSYYEIEKSIEDNPLFDTAKAQKKLRAFVEQHQQTIHTKAEIVLDHFIPHIVNQKRLKGKAKAMVVTQSIESAIKYYKALTTILEAKGHPFKIIIAFSGTKTLNGIDYSEAEMNGFGDKDTSDKFDEDEYRMLIVANKYLTGFDQPKLCAMYVDKKLQGVMAVQALSRLNRSANKLGKKTEDLFILDFFNSTEDIKTSFDPFYTATSLSQATDVNVLHELKDVLDEVGVYEWEEVENFNELFFQKVDAQLLSPIIDTAAERFKTELELEDEEKADFKIKAKQFVKIYGQMASILPFEVVQWEKLFWFLKFLVPKLPISDTNVDGMDELLESVDLSTYGLERVKLNHSIGLEDSDSELDPQNPSPRGAYGGEEERDPLELIIQSFNERWFQGWEATPDDQRLKFISLSKSIQAHPDFQTKVAENHDEQNKDLAFRKILDDVMSKQRKQELDLYRLYAKDESFYQAFFDTMKRMASVGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJR0</accession>
    <name>A0A5C6ZJR0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">BamA/TamA family outer membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_09205</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019867">
        <property type="term" value="C:outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000184">
        <property type="entry name" value="Bac_surfAg_D15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039910">
        <property type="entry name" value="D15-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12815">
        <property type="entry name" value="PTHR12815"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01103">
        <property type="entry name" value="Omp85"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Omp85" evidence="2">
        <location>
            <begin position="447"/>
            <end position="746"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="746" mass="84811" checksum="9D1BE5BDB8F7982D" modified="2019-11-13" version="1">MGLYSCSVKKFIPEGQRLYTGATIEIEADSSITEVDELKERLQTVLRPEPNSKFLGMQPGLYFYYKAQRKKPGFINRFLNKKIGEEPVYQIDVAPLEVEDVLLNRLENSGFFYSASSSSFTEDSLEASLTYRLKVPKPYKMANFKLDSMPSPIYKDVQELTANTPLRETNRFSLNNMKLERERIEQGLKSRGYYNFNPDFFIFEADTNQYNNKQFDLFMKLKAEVPKKSLVPYQIKQINVYPNYDLNDSTQIEVNRFKSKNFYQDTLFFKPKYLNKYITLEEGQYFNPKTSKNTARRLSTIGAYKFVNVQYKEIDSSMTDSLGALEANIYLSPLTKRALRAELQAVTKSNGFTGPNLALTYSNRNLFQGGETMNISTTVGYETQIASGDNRGLSSLELGLKGELIFPRVISPFNIGDDFFEYSIPKTKTSLGLKYLNRSQLYTLLSGSALFGYLWDANKYVTYELNPISINYTSLSNTTPEFQTILDENPFLQRSFDQQFISGLTLSFTYNGMVDANDPNQFYVNSTLDVAGNSISLLGKENSETGVKEFLGLEYAQYAKADVDLRFHLNFGKDRQQTLATRLFAGYGLPYGNSDVVPFVKQYFSGGPYSVRAFRNRSLGPGVYNEDNDTGNNGGFFDRTGNIRLEANIEYRFPIVSFFKGAVFADAGNVWNSEPNPAFNGLDEFSSNFINELGMGVGFGLRVDVQGFVIRFDLAAPFHDPSLPKGERYDFQYDQPVFNFAIGYPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJS4</accession>
    <name>A0A5C6ZJS4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Molecular chaperone HtpG</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">htpG</name>
        <name evidence="5" type="ORF">ESY86_04775</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the heat shock protein 90 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019805">
        <property type="entry name" value="Heat_shock_protein_90_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037196">
        <property type="entry name" value="HSP90_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001404">
        <property type="entry name" value="Hsp90_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020575">
        <property type="entry name" value="Hsp90_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11528">
        <property type="entry name" value="PTHR11528"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00183">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002583">
        <property type="entry name" value="Hsp90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00775">
        <property type="entry name" value="HEATSHOCK90"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00298">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="637" mass="72893" checksum="014B340FB62289B6" modified="2019-11-13" version="1">MTKGNINVSVENIFPLIKKFLYSDHEIFLRELISNATDATLKLKHLTSIGEISVEYGSPKIEIKIDKEGNKLHITDQGVGMTAEEVEKYINQIAFSGAEEFLEKYKEAGKDTGIIGHFGLGFYSAFMVASKVEIITKSYKDEPAVHWMCDGSPEFSLEETEKAERGTEIILHMAEDSTEFLEESRIRELLTKYNKFMPIPIKFGTKEINDPEFTPKEIKDKEGKETTEPHKKISVDNIINNPDPAWTKQPADLETKDYQEFYRELYPMQFEEPLFHIHLNVDYPFNLTGILYFPKMTNDLNIQRDKIQLYQNQVFVTDNVEGIVPEFLTMLKGVIDSPDIPLNVSRSYLQADGAVKKISSYITRKVADKLKSLFNENREDFEAKWNDIKIVIEYGMLSEDKFFDKADAFALYPTVDGKYYTYQELFDKTKEKQTDKDGKLVVLYASNEDTQHSYIEAAKAKGYEVLLLDSPIVPHLIQKLESSKENISFARVDGDHIDNLIKTEETAISKLSDDEKKQLEDILKDAIPAEKFSVQLEAMDSDASPFIITQPEFMRRMKEMQQTGGGGGMFGMGNMPEMYNLVVNTNSELVGEILNTKTKKKQERLITQSLDLARLSQGLLKGKELTDFVKRSYEMIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJT6</accession>
    <name>A0A5C6ZJT6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_08395</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="131" mass="15323" checksum="00A3C6DE8BCDE538" modified="2019-11-13" version="1">MKKDIIIPKVDNVFVAIVQEEHHEYKTMDWNAYIINNKDVDLDTVLIASKGFSKDKITPVMRHSLKLLPARSYAKIEFMQERLLALNNEFKVSFFEGNQLFDKTYTFKKNTINENALQKIPLMQLKGVLMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-12-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK05</accession>
    <name>A0A5C6ZK05_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Tyrosine-type recombinase/integrase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_05295</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035386">
        <property type="entry name" value="Arm-DNA-bind_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025269">
        <property type="entry name" value="SAM-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17293">
        <property type="entry name" value="Arm-DNA-bind_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13102">
        <property type="entry name" value="Phage_int_SAM_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="3">
        <location>
            <begin position="250"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD90159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="444" mass="51627" checksum="6988DC569A647938" modified="2019-11-13" version="1">MANIKIVLRKNMIKKDGTIPLAIRISANYKTNYKWLGQYVLAKDWDKVAGQAKRSHPNYKMLNNFLLKKLTEANDVYLNNQDENITPKQVKQKLKGPGGSKSFFAVAAQRIKTKYDRKVFSVAKSELSILYNIEEFLNLKTSLTKKDVIEGIAKRRKDRVGKARKSEYSFIDGIEHFQKKKDLKFQDINQAFLERYKTFCSAYLNQKTRTISNQLIFIRTLFNVAIKDGVVSAKYYPFAGDKEKIRLGTSNKIGLTIEEVEKIESLKLEPYSSIWHTHNVWLISFYFAGIRISDVVKLKWSDFKDDRLYYVMNKNEKPLSLKVPEKAKAILDFYKMNRKNNGGYIFPFLNEVRPNDDEDFFTKTRNATKLFNKYLIRIAAQCDIDKSLSNHIARHTFGNIAGDKIHPLMLQKLYRHSDLKTTLNYQANFIHRDADDALDSVISF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK15</accession>
    <name>A0A5C6ZK15_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nicotinic acid mononucleotide adenyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_08405</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022663342" evidence="2">
        <location>
            <begin position="22"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="292"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="304"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="320" mass="36843" checksum="645EDFE4940A2C5B" modified="2019-11-13" version="1">MKTTKLLLGFALLAVFLTSCYKEEIIVDDLGETPPTSVNQMLNTYELWYVDVNQTLGAGETPFLQIAFTLSFRNGVLYANNNLVGFGSQGNGFGIDVGTYDAFDGILDVNHDVDGYQTFDIFQIDYNTIELYNPFNDTSYFLNGYQRNTFDYDFVFYDNIHYFLQEYEAWEKTYTSQFGALNDFDNETYLQFLSGGNDSEFRSSRDVNLNNPNSIFWDYMGVYGVGNLSNNSALKTLTLDYDYFNNEYFELSVINDQRIELFHQTSGTIYEFSGRGYIQYLRAAETAEKGDATNKNTEVFLKKRKQKTPKKANPRHSTRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK29</accession>
    <name>A0A5C6ZK29_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GTP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_05465</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SIMIBI class G3E GTPase family. CobW subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011629">
        <property type="entry name" value="Cbl_biosynth_CobW-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036627">
        <property type="entry name" value="CobW-likC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07683">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00833">
        <property type="entry name" value="CobW_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CobW C-terminal" evidence="2">
        <location>
            <begin position="257"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="406" mass="46060" checksum="BD52DBF31A98EA06" modified="2019-11-13" version="1">MTKKLPVTVLSGFLGAGKTTLLNHILHNKEGLKVAVIVNDMSEVNIDAQLVKNENTLSRTEERLVEMSNGCICCTLREDLMIEVEKLAKENRFDYLLIESTGISEPIPVAQTFSFESEDGSIDLSRFSYVDTMVTVVDGFNFLKDFSSPDYLTSRNLTDIENDTRTIVNLLTDQVEFANVIILNKIDLITEEKLKQLYGILQKLNPNARIIPAKNSAVPLSEIIGTKLFDFEEAENSAGWIQELENEHTPETEEYGIGSMVFRSKTPFHTERFWEFATSGFPANILRSKGLFWLSSRPEQALIWSSAGGSLKTDPAGVWWASMPFSERIGYAAFVDNQSFIESDWHQTYGDRKVELVFIAQNLDRDKLTNLLEKCLLTSDEQKLWKNGELQVTDHWPIETLEYTKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKA2</accession>
    <name>A0A5C6ZKA2_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Valine--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Valyl-tRNA synthetase</fullName>
            <shortName evidence="8">ValRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">valS</name>
        <name evidence="13" type="ORF">ESY86_05910</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-valine + tRNA(Val) = AMP + diphosphate + L-valyl-tRNA(Val)</text>
            <dbReference type="Rhea" id="RHEA:10704"/>
            <dbReference type="Rhea" id="RHEA-COMP:9672"/>
            <dbReference type="Rhea" id="RHEA-COMP:9708"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78537"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.9"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">The C-terminal coiled-coil domain is crucial for aminoacylation activity.</text>
    </comment>
    <comment type="domain">
        <text evidence="8">ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.9" evidence="8"/>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004832">
        <property type="term" value="F:valine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006438">
        <property type="term" value="P:valyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07962">
        <property type="entry name" value="Anticodon_Ia_Val"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.740.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02004">
        <property type="entry name" value="Val_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033705">
        <property type="entry name" value="Anticodon_Ia_Val"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037118">
        <property type="entry name" value="Val-tRNA_synth_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019499">
        <property type="entry name" value="Val-tRNA_synth_tRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002303">
        <property type="entry name" value="Valyl-tRNA_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11946">
        <property type="entry name" value="PTHR11946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10458">
        <property type="entry name" value="Val_tRNA-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00986">
        <property type="entry name" value="TRNASYNTHVAL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="SSF46589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="SSF50677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00422">
        <property type="entry name" value="valS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1" evidence="10">
        <location>
            <begin position="15"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_1" evidence="11">
        <location>
            <begin position="616"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="domain" description="Val_tRNA-synt_C" evidence="12">
        <location>
            <begin position="811"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="8">
        <location>
            <begin position="43"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="8">
        <location>
            <begin position="535"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="538"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF10458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="TXD90269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="876" mass="100729" checksum="3F42890EB7B6C2E0" modified="2019-11-13" version="1">MEIPSKYSAEAVENKWYNYWMQHGYFNSKPDDREPYTIVIPPPNVTGVLHMGHMLNNTIQDVLIRRARLQGKNACWVPGTDHASIATEAKVVAKLRAQGIDKNNLTRDEFLKHAWDWTNEYGGVILEQLKKLGCSCDWERTKFTMDDDMNESVIKVFVDLYNKGLIYRGYRMVNWDPEAKTTLSDEEVIHLERTDKLYYVNYKIQDDDGYVTLATTRPETILGDTAVCVNPNDERYAHLKGKHVIVPICNRVVPIIFDDYVDMEFGTGCLKITPAHDVNDKAIGQRHHLEIIDILNDDATLNSYGMHHQGKDRVAARMAVAQELDEMSILVKTEDITHKVGTSERTRAVIEPRLSDQWFLKMEDLAKPAIKAVLEDETVKLFPKRFNNTYRHWMENIRDWNISRQLLWGQQIPAYYYGDGKEDFVVAESIEEALKLAQERSNNPKLNISDLRQETDALDTWFSSWLWPISVFDGIRNPENEDINYYYPTNDLVTGPDILFFWVARMIVAGFEYRNERPFENVYLTGLVRDKQRRKMSKSLGNSPDALKLIKDYGADGVRVGLLLSAAAGNDLMFDEDLCGQGKGFSNKIWNAFRLVQGWEVANIEQPEASKLAIEWFEHKFQSALVEIEDHYSKYRLSDVLMTAYKLVWDDFCSWLLEMIKPAYQQPIDAKTFKEVTAIFENNLKILHPFMPFITEEIWQYTKERSPEEALIVAKYPEMTAFDSKLISDFETVKDVVSGIRTIRTDKNIPFKDTIELMALNNENLDERYNSVITKLGNISTLKSVTEPVEGALTFRVLSNEYFIPISGAIDVEAEIAKLSEELKYTEGFLKSVQGKLKNERFVNNAPDAVVASERKKEADALATVETLKASLKNLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKI4</accession>
    <name>A0A5C6ZKI4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GIY-YIG nuclease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035901">
        <property type="entry name" value="GIY-YIG_endonuc_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01541">
        <property type="entry name" value="GIY-YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82771">
        <property type="entry name" value="SSF82771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GIY-YIG" evidence="1">
        <location>
            <begin position="2"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="84" mass="9838" checksum="4B38EA7FA8F707CF" modified="2019-11-13" version="1">MLDFVTYILASEKTANLYKGHTSNLIGRFKSHNGLSKKGWTVRYRPWRVVYVRFFATKSEAMGHEHWLKSGAGREWIKDHQKAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKI5</accession>
    <name>A0A5C6ZKI5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="242" mass="27476" checksum="65828EA843412E92" modified="2019-11-13" version="1">MAKPKKVLKIIGGVILFFTLPTLLLFAFMYFKYNEDLPIGKEGVAADALAEKMLGSLNAEAYMATDYIEFTFKKRQHFKWNKAENTCEVYWKNFKVNLDLDNHNNSKAFEGESQTEGEARQELIEKAVNLFNNDSFWLVAPYKVFDAGTERRLVKSEGKNDALLVTYTNGGSTPGDSYLWHLDASGKPQSFQMWVDILPIDGLEASWGNWTTTSTGAQLPTFHKFLVFGIEIDDIKTTRNIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKX9</accession>
    <name>A0A5C6ZKX9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Dihydrolipoyl dehydrogenase</fullName>
            <ecNumber evidence="3 13">1.8.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="primary">lpdA</name>
        <name evidence="16" type="ORF">ESY86_06395</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>(R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + NAD(+) = (R)-N(6)-lipoyl-L-lysyl-[protein] + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:15045"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="EC" id="1.8.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11 13">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="11 13">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="13">The active site is a redox-active disulfide bond.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.4" evidence="3 13"/>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004148">
        <property type="term" value="F:dihydrolipoyl dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006258">
        <property type="entry name" value="Lipoamide_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012999">
        <property type="entry name" value="Pyr_OxRdtase_I_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01350">
        <property type="entry name" value="lipoamide_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00076">
        <property type="entry name" value="PYRIDINE_REDOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 11 13" id="KW-0274">FAD</keyword>
    <keyword evidence="4 13" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7 11 13" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 13 16" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9 13" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="15">
        <location>
            <begin position="4"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_dim" evidence="14">
        <location>
            <begin position="346"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="444"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="143"/>
            <end position="145"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="180"/>
            <end position="187"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="271"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="312"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="318"/>
            <end position="321"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="12">
        <location>
            <begin position="42"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="TXD89828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="466" mass="50721" checksum="17E8CAEACF6EAE98" modified="2019-11-13" version="1">MKSYDVAIIGSGPGGYVAAIRCAQLGMKTAIIEKYSTLGGTCLNVGCIPSKALLDSSHHYDDAIKHFEEHGIDIPGEIKVNLKQMISRKQAVVDQTTSGIDFLMKKNKIDVYEGMGSFKDATHIKIEGKESLEIEAKNIIIATGSKPANLPFIKLDKERIITSTEALKLKEIPKHMIIIGGGVIGLELGQVYKRLGAEVTVVEYMDRIIPSMDAGLSKELNKVFKKAKFNINVSHKVKSVERKGDEVIVKADNKKGEEVEFKGDYCLVSVGRRPYTDGLNAEAAGVNINDRGQVEVNGHLQTNVKNIYAIGDVIKGAMLAHKAEEEGVFVAEVLAGQKPHIDYNLIPGVVYTWPEVASVGKTEEELKEAGTEYKTGQFPMRALGRSRASMDTDGFVKILADKKTDEILGVHMIGARCADLIAEAVVAMEYKASAEDIARMSHAHPTYAEAVKEAALAATEDRALHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL87</accession>
    <name>A0A5C6ZL87_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 7">Threonylcarbamoyl-AMP synthase</fullName>
            <shortName evidence="7">TC-AMP synthase</shortName>
            <ecNumber evidence="4 7">2.7.7.87</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 7">L-threonylcarbamoyladenylate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ESY86_07050</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + hydrogencarbonate + L-threonine = diphosphate + H2O + L-threonylcarbamoyladenylate</text>
            <dbReference type="Rhea" id="RHEA:36407"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="ChEBI" id="CHEBI:73682"/>
            <dbReference type="EC" id="2.7.7.87"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the SUA5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.87" evidence="4 7"/>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061710">
        <property type="term" value="F:L-threonylcarbamoyladenylate synthase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038385">
        <property type="entry name" value="Sua5/YwlC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005145">
        <property type="entry name" value="Sua5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010923">
        <property type="entry name" value="T(6)A37_SUA5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006070">
        <property type="entry name" value="YrdC-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03481">
        <property type="entry name" value="SUA5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01300">
        <property type="entry name" value="Sua5_yciO_yrdC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004930">
        <property type="entry name" value="Tln_factor_SUA5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="SSF55821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00057">
        <property type="entry name" value="TIGR00057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51163">
        <property type="entry name" value="YRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="YrdC-like" evidence="9">
        <location>
            <begin position="5"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>L-threonine</name>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>L-threonine</name>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="109"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="113"/>
        </location>
        <ligand>
            <name>L-threonine</name>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>L-threonine</name>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>L-threonine</name>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="223"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR004930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR004930-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD89948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="320" mass="35210" checksum="EEDE85C8A6CC0B25" modified="2019-11-13" version="1">MTIISTDISKAIELLNNEDVVAIPTETVYGLAGNIYSEKAIRKIFQVKQRPFFNPLIVHIDSIEKIDGIVSEFPEQAKMLAAAFWPGALTLVLKKKPNIPDLITAGKNTVAVRVPNHPTTLSLLQKLSFPLAAPSANPFGSISPTSSVHVNNYFKNTIPMVLEGGACKNGIESTIIGFENNEAVLYRLGSISIEEIENVIGKLKVKNKKEIAPNAPGMLARHYAPKTGTYLVKDAEKFIKDYTDKKIGVLRFSNEMNSLNCMHLEVLSRKGDLKEAASNLYAALHRLDNLNLDMIVAELFPNIGLGKSINDRLVRATKNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL98</accession>
    <name>A0A5C6ZL98_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Acyl-CoA reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_00135</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003995">
        <property type="term" value="F:acyl-CoA dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008218">
        <property type="term" value="P:bioluminescence"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008670">
        <property type="entry name" value="CoA_reduct_LuxC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05893">
        <property type="entry name" value="LuxC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="353" mass="40818" checksum="A758AEDE30E5DD82" modified="2019-11-13" version="1">MDLQQRINAFAKLGNFLSQFTSEGIRRKDEIPHNDLFFEGFQHQIKLAQEHNGWFTKENVFFALEGWSKQLTESNLNTWVEKYQFNISSPKTIAIVMAGNIPLVGFHDFLSVLISGQNVLVKQSSNDKHLLPFLAKYLEHVEPAFRGKISFTEGRLEQFDAVIATGSDNTARYFEYYFKDKPSIIRKNRNSIAVLRGNESDGELKALSEDVFRYYGLGCRNVSKIFVPKDYEFDAFFNGMYHWHPIINQSKYANNYDYNKAVYLMSEFQMLENGFLMIKEDANFSSPIATVFYEYYDSEADLKTMLDDRKDQIQCVVAHGFRDDEIQFGQTQLPNLGDYADDVDTISFALTIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLC4</accession>
    <name>A0A5C6ZLC4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_05505</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="109" mass="12254" checksum="78EBFB6A1DBF3D53" modified="2019-11-13" version="1">MDNTKQIGKNIAAFLLLVALMFPTAIQLLHSCEGHEHIAYEGSSSQIHQEVSDCHICDFHLASFNYDISEYPNFHLPIIPVKIETDLSSLQLHSFITTNTQLRAPPTFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLC8</accession>
    <name>A0A5C6ZLC8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transporter substrate-binding domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_00735</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015276">
        <property type="term" value="F:ligand-gated ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001320">
        <property type="entry name" value="Iontro_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00060">
        <property type="entry name" value="Lig_chan"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00079">
        <property type="entry name" value="PBPe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="146"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="179"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="212"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="PBPb" evidence="6">
        <location>
            <begin position="37"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="PBPe" evidence="7">
        <location>
            <begin position="37"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD91148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="367" mass="40889" checksum="EF4C707C27B1C229" modified="2019-11-13" version="1">MIYKFKSLILIVLVFLLNHLQPNLYAQNTNRISSKDTLQVGIAGSEPFVFSDAANAEGIAIEIWENIAKQKKWNFKYRPFDTVEDALHSLENGKLDLVVGPISITANRVEYLRFSQPFYNSSLAILSRADALNIWQKIKPLFSAKLIVAVFIFLFILAIVGTLLWLAERKQSPDQFSQSPVKGVGTGMWLAIVTMSTTGYGDKAPITLAGRIIAGSWMIISIIFATSMIAGIASTLTLTSMGSSTVSTIEELSGRKTATVIGSPTESYLKAYKTKITGVSTLDDAISKLREKEVDAVVYDRPQLLYYLKNHRNDDLFIAKAEYYKQGYGFAFPLSSTLVYDVNRALLRLAEAQKTTKIIDFYLDKDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLG0</accession>
    <name>A0A5C6ZLG0_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Chaperonin GroEL</fullName>
            <ecNumber evidence="6">5.6.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">60 kDa chaperonin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Chaperonin-60</fullName>
            <shortName evidence="6">Cpn60</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">groL</name>
        <name evidence="6" type="synonym">groEL</name>
        <name evidence="9" type="ORF">ESY86_05730</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 8">Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6 8">Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the chaperonin (HSP60) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.1.7" evidence="6"/>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03344">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00600">
        <property type="entry name" value="CH60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018370">
        <property type="entry name" value="Chaperonin_Cpn60_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001844">
        <property type="entry name" value="Cpn60/GroEL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00298">
        <property type="entry name" value="CHAPERONIN60"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="SSF48592"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="SSF52029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="SSF54849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02348">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00296">
        <property type="entry name" value="CHAPERONINS_CPN60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="29"/>
            <end position="32"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="50"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="86"/>
            <end position="90"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="415"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="495"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD90237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="544" mass="57107" checksum="CF7DD60A4A863D74" modified="2019-11-13" version="1">MAKNIIFDIQSRDGLKRGVDALANAVKVTLGPKGRNVIIGKSFGAPQVTKDGVTVAKEIELEDALENMGAQMVKEVASKTNDLAGDGTTTATVLAQAIVTEGLKNVAAGANPMDLKRGIDKAVAEIVRELQKQSKKVGNSSEMIKQVASISANNDETIGDLIAKAFGKVGKEGVITVEEAKGTDTYVDVVEGMQFDRGYLSPYFVTDSDKMIADLENPYILLFDKKISNLQEILPILEPVAQSGRPLLIIAEDVDGQALATLVVNKLRGGLKIAAVKAPGFGDRRKAMLEDIAILTGGVVISEERGFSLENADLTMLGSAETVTVDKDTTTIVNGAGKAADIKARVNQIKAQIETTTSDYDKEKLQERLAKLAGGVAVLYVGAASEVEMKEKKDRVDDALHATRAAVEEGIVAGGGVALVRTIAVIKKLSADNADEATGIQIVARAIESPLRTIVSNAGGEGSVVLAKVLEGKKDYGFDAKSETYVDMLKAGIIDPTKVTRIALENAASIAGMILTTECALVDIKEDSAGGMSGGMGGGMPGMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLR3</accession>
    <name>A0A5C6ZLR3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Deoxynucleoside kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_02370</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019136">
        <property type="term" value="F:deoxynucleoside kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01673">
        <property type="entry name" value="dNK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002624">
        <property type="entry name" value="DCK/DGK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031314">
        <property type="entry name" value="DNK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01712">
        <property type="entry name" value="dNK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000705">
        <property type="entry name" value="DNK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="dNK" evidence="4">
        <location>
            <begin position="4"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="7"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="180"/>
            <end position="182"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000705-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000705-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000705-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="204" mass="23840" checksum="B1552D481072FE78" modified="2019-11-13" version="1">MHVAVAGNIGAGKTTLTNLLAKHYRWEPQLEDVVDNPYLDDFYNQMERWSFNLQVYFLNSRFRQIKLIHESGKDIIQDRTIYEDAHIFAPNLHAMGLMTNRDFENYKSLFDLMQTFVEGPDLLIYLRSSIQNLVAQIHKRGRDYENSISIDYLSRLNERYEAWVHGYDKGNLLIIDVDQLDFVSSPEDLGFVINKIDAQINGLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLR5</accession>
    <name>A0A5C6ZLR5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_05475</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024453">
        <property type="entry name" value="Peptidase_C92"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05708">
        <property type="entry name" value="Peptidase_C92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="221" mass="25196" checksum="92B09A2FF1BA7721" modified="2019-11-13" version="1">MKIRLLNKLLFFYCCTLSISCNHSYQKVGFQEGDLLFQNLNCGELCNAIEAVTEGIDGKDFSHIALVVNVNDTLKVIEAIGNNVQINSLETFFSRSGDTAKIENVTVGRLKKQYKNLIPKAIAEAKKIIGQPYDNIFLLNNGKMYCSEMIYEIFKESNKTKDFFVLEPMTFKDPKTKVFFPAWVNYYKHLNKEIPEGLLGINPGLISRSNKISILKIENYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLT0</accession>
    <name>A0A5C6ZLT0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CoA transferase subunit B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_07560</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 3-oxoacid CoA-transferase subunit B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008410">
        <property type="term" value="F:CoA-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012791">
        <property type="entry name" value="3-oxoacid_CoA-transf_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004165">
        <property type="entry name" value="CoA_trans_fam_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004164">
        <property type="entry name" value="CoA_transf_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13707">
        <property type="entry name" value="PTHR13707"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01144">
        <property type="entry name" value="CoA_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00882">
        <property type="entry name" value="CoA_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02428">
        <property type="entry name" value="pcaJ_scoB_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01274">
        <property type="entry name" value="COA_TRANSF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="217" mass="23175" checksum="75BADC9A94FDE66B" modified="2019-11-13" version="1">MLDKNGIAKRIAKEVKDGYYVNLGIGIPTLVANYVRDDIEVEFQSENGVLGMGPFPFEGEEDADIINAGKQTITTLPGASFFDSALSFAMIRGQHVDLTILGAMEVAENGDIANWKIPGKMVKGMGGAMDLVASAENIVVAMMHTNRAGESKLLKRCSLPLTGVGCVKKIVTNLAVIEVTENGFKLLERAPGVSVDEIIAATEGHLLVEGDIPEMQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLV0</accession>
    <name>A0A5C6ZLV0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF3891 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_06845</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024992">
        <property type="entry name" value="DUF3891"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13030">
        <property type="entry name" value="DUF3891"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="248" mass="28926" checksum="0BA574ECCA4A7272" modified="2019-11-13" version="1">MIVNKSVVGIHIISHEAHGLLAGKIANEIKPEFRPRHWFETLIAICEHDDRQLNFKEKDYLSDMGVPMDFNEERSSVHEVMTRMQRVLKAAGDKSSWVKLLISYHLEFIYAHMKADSKRISRFFTEEEKARGHILEQFKVSDKTGRTYYEVLRFCDRLSLILCKDQAPEAERLLEINTSINGETYFIKKTENGVLTITPWIFSATEFELSVEERILKETKFTSNQHFETVLMGSKPQPKKWLLKKSEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM69</accession>
    <name>A0A5C6ZM69_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024445">
        <property type="entry name" value="Tnp_ISXO2-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12762">
        <property type="entry name" value="DDE_Tnp_IS1595"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DDE_Tnp_IS1595" evidence="1">
        <location>
            <begin position="19"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="83" mass="10427" checksum="FCCC93883A79650D" modified="2019-11-13" version="1">MERIYTSEKKFLKLKQMTSEDGKNFKELHIHIMNIKGWLRGIHHHYSKEHMQNYLDEYHFRYNRRSNRDTIFDVLIRTMVHYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMA5</accession>
    <name>A0A5C6ZMA5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Pyruvate carboxylase</fullName>
            <ecNumber evidence="3 8">6.4.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">ESY86_04740</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>ATP + hydrogencarbonate + pyruvate = ADP + H(+) + oxaloacetate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20844"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.4.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>biotin</name>
            <dbReference type="ChEBI" id="CHEBI:57586"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.4.1.1" evidence="3 8"/>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004736">
        <property type="term" value="F:pyruvate carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006090">
        <property type="term" value="P:pyruvate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005481">
        <property type="entry name" value="BC-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001882">
        <property type="entry name" value="Biotin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011764">
        <property type="entry name" value="Biotin_carboxylation_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005482">
        <property type="entry name" value="Biotin_COase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003379">
        <property type="entry name" value="Carboxylase_cons_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005479">
        <property type="entry name" value="CbamoylP_synth_lsu-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005930">
        <property type="entry name" value="Pyruv_COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02785">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00289">
        <property type="entry name" value="Biotin_carb_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02786">
        <property type="entry name" value="CPSase_L_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02436">
        <property type="entry name" value="PYC_OADA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001594">
        <property type="entry name" value="Pyruv_carbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00878">
        <property type="entry name" value="Biotin_carb_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01235">
        <property type="entry name" value="pyruv_carbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50979">
        <property type="entry name" value="BC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00188">
        <property type="entry name" value="BIOTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00866">
        <property type="entry name" value="CPSASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00867">
        <property type="entry name" value="CPSASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 8" id="KW-0092">Biotin</keyword>
    <keyword evidence="4 8 16" id="KW-0436">Ligase</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin carboxylation" evidence="14">
        <location>
            <begin position="2"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="13">
        <location>
            <begin position="122"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="15">
        <location>
            <begin position="533"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="domain" description="Lipoyl-binding" evidence="12">
        <location>
            <begin position="1072"/>
            <end position="1150"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="294"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="237"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="542"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="614"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" description="via carbamate group" evidence="11">
        <location>
            <position position="712"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="741"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="743"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="876"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR001594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001594-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001594-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR001594-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="TXD90063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1150" mass="129576" checksum="8FBD810FDC9F2C4A" modified="2019-11-13" version="1">MKIKKVLIANRGEIAIRVLRACTELNLKTVAVYTYEDRYSQHRNKADESYQIGENDQPLRPYLNIDLLIRLAKSKGVDAIHPGYGFLSENSEFARQCAANGIIFIGPEPEVMDALGDKITAKKVAVKCHVPIIESNKKKLSSLKIAIAEAKSIGYPLMLKAASGGGGRGMRIIKKEEDLENNFDSARNEAANAFGDDTMFLEKYVENPKHIEVQIVADNYGNIRHLHERDCSVQRRHQKVVEIAPSHNVSDKVKQDLYKYAVDIAKQVNYNNIGTVEFLVDKEDQIYFIEVNPRIQVEHTVTEMVTGIDLVKTQIFVAGGYKLDSKQIKIYGQDSISTYGFALQCRLTTEDPANNFTPDYGSVTTYRSASGMGIRLDAGSIYQGYNISPFFDSLLVKVSSHGRTLDGATRKMVRALKEFRIRGVKTNIHFLQNVIQHPTFKDGKATVNFIQNTPSLFKIDLPQDRTSKVVNFLAEVIVNGNSDVKNIEENKVFRNPKIPKFDSEATHPKGSKDMLTEMGPEKFCQWLMAEKKIHFTDTTMRDAHQSLLATRMRTFDMMKVAESYAKNHPQIFSMEVWGGATFDVCMRFLYESPWTRLRQLRQAMPNVLFQMLLRGSNAVGYKAYPDNLIEKFVEKSWENGVDVFRIFDSLNWVKAMEPSINYVRNKTGGIAEAALSYTGDILDVKETKYTLAYYTQLAKDLENAGAHMIAIKDMAGLLKPYAATELVAALKDTVKLPIHLHTHDTSSLQSATYLKAIEAGVDVVDVALGGLSGLTSQPNFNAIVEMMKNQPRAHDFDMVKLNEFSNFWEDTRELYYPFESGLKAGTAEVFQHEIPGGQYSNLRPQAIALGIGDRFDEVKRMYAAVNTLFGNLIKVTPSSKVVGDMAIFMVTNNLTTDDVMQRGEEISFPESVISFFMGDLGQPTGGFPKKLQKIILKNRKPFTNRPNAHLEPIDFDGEFEAFKKKFQKGFTRTMEMEDFLSYTLYPKVYEKAHENYKKYGNLTLVPTENFFYGMKLREEILIDLEPGKTVIIKLLSVGIPNDTGVRTVFFKVNGENRFVEVLDTSLNIKVEQNTKTDPENTNHVGAPLQGSLYKILVKKGQAIKENDPLFVIEAMKMETTVTAFKSGKVKAVALKEGAMVKQDDLVITME</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMD4</accession>
    <name>A0A5C6ZMD4_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">D-aminoacyl-tRNA deacylase</fullName>
            <shortName evidence="1">DTD</shortName>
            <ecNumber evidence="1">3.1.1.96</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Gly-tRNA(Ala) deacylase</fullName>
            <ecNumber evidence="1">3.1.1.-</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">dtd</name>
        <name evidence="2" type="ORF">ESY86_02445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a D-aminoacyl-tRNA + H2O = a D-alpha-amino acid + a tRNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13953"/>
            <dbReference type="Rhea" id="RHEA-COMP:10123"/>
            <dbReference type="Rhea" id="RHEA-COMP:10124"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59871"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:79333"/>
            <dbReference type="EC" id="3.1.1.96"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>glycyl-tRNA(Ala) + H2O = glycine + H(+) + tRNA(Ala)</text>
            <dbReference type="Rhea" id="RHEA:53744"/>
            <dbReference type="Rhea" id="RHEA-COMP:9657"/>
            <dbReference type="Rhea" id="RHEA-COMP:13640"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78522"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="1">A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DTD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.96" evidence="1"/>
    <dbReference type="EC" id="3.1.1.-" evidence="1"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051499">
        <property type="term" value="F:D-aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106026">
        <property type="term" value="F:Gly-tRNA(Ala) hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043908">
        <property type="term" value="F:Ser(Gly)-tRNA(Ala) hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019478">
        <property type="term" value="P:D-amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00518">
        <property type="entry name" value="Deacylase_Dtd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003732">
        <property type="entry name" value="Daa-tRNA_deacyls_DTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023509">
        <property type="entry name" value="DTD-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10472">
        <property type="entry name" value="PTHR10472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02580">
        <property type="entry name" value="Tyr_Deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69500">
        <property type="entry name" value="SSF69500"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00256">
        <property type="entry name" value="TIGR00256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1" id="KW-0820">tRNA-binding</keyword>
    <feature type="short sequence motif" description="Gly-cisPro motif, important for rejection of L-amino acids" evidence="1">
        <location>
            <begin position="138"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="149" mass="16382" checksum="4DD1C6C40A4E836D" modified="2019-11-13" version="1">MKAVLQRVSEARVSIHNEEVASIKQGLLILIGIVANDTPDDIKWLSNKIVNCRIFPDDAQVMNNSILQNQGDIIVVSQFTLHANTKKGHRPSYIAAAKPEIAIPIYEAFIKQLESDLGKPVQTGAFGADMQVQLINDGPVTLIIDTEHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMD5</accession>
    <name>A0A5C6ZMD5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Amidinotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_04145</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014541">
        <property type="entry name" value="Amdntrnsf_FN0238"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43224">
        <property type="entry name" value="PTHR43224"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028188">
        <property type="entry name" value="Amdntrnsf_FN0238"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="310" mass="34972" checksum="96B53EA443CBFBFE" modified="2019-11-13" version="1">MSQITNTILMIRPISFRMNEETAVNNYFQQDLSIKNAEINAKAQHEFDAFVEKLKAVGVNVIVVQDDKTPDTPDSIFPNNWVSFHENGDIGLYPMFAENRRKERREDVFLTLEEAGFKINNIVDYTTAEDEALYLEGTGSILLDRVHRKAYCALSPRADEDLFIEFCEDFEYTPVVFNAYQDVDGKRLAIYHTNVMMCLATDFAVICLDSIDDKKERKTVVNSLKQDGKTIIAISEAQMHEFAGNMLQVEGKNGQAYLVMSHAAHESLTTQQVGTIEKFCPILSSSLETIETCGGGSARCMMAEVFLPRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN05</accession>
    <name>A0A5C6ZN05_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphoserine aminotransferase</fullName>
            <ecNumber evidence="6">2.6.1.52</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Phosphohydroxythreonine aminotransferase</fullName>
            <shortName evidence="6">PSAT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">serC</name>
        <name evidence="8" type="ORF">ESY86_00140</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>2-oxoglutarate + 4-(phosphooxy)-L-threonine = (R)-3-hydroxy-2-oxo-4-phosphooxybutanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:16573"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58452"/>
            <dbReference type="ChEBI" id="CHEBI:58538"/>
            <dbReference type="EC" id="2.6.1.52"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 6">
            <text>2-oxoglutarate + O-phospho-L-serine = 3-phosphooxypyruvate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:14329"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:18110"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57524"/>
            <dbReference type="EC" id="2.6.1.52"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
        <text evidence="6">Binds 1 pyridoxal phosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 6">Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 2/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Cofactor biosynthesis; pyridoxine 5'-phosphate biosynthesis; pyridoxine 5'-phosphate from D-erythrose 4-phosphate: step 3/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 6">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.52" evidence="6"/>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00135">
        <property type="reaction ID" value="UER00197"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00244">
        <property type="reaction ID" value="UER00311"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004648">
        <property type="term" value="F:O-phospho-L-serine:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006564">
        <property type="term" value="P:L-serine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008615">
        <property type="term" value="P:pyridoxine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00160">
        <property type="entry name" value="SerC_aminotrans_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022278">
        <property type="entry name" value="Pser_aminoTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43247">
        <property type="entry name" value="PTHR43247"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000525">
        <property type="entry name" value="SerC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-0664">Pyridoxine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0718">Serine biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="7">
        <location>
            <begin position="3"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="6">
        <location>
            <begin position="76"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="6">
        <location>
            <begin position="232"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="6">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD91045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="354" mass="39262" checksum="57D61E2B5AEE8FAF" modified="2019-11-13" version="1">MKIHNFSAGPCILPQEVFEKSSQAVLNFNNDGLSILEISHRSKAFVDVMENARALALELLGLEGKGYKALFLQGGASTQFLMAAMNLMEKKAAYLNTGTWSDNAIKEAKIYGEVAEVASSKEANYNYIPKGYKVPKDCDYFHCTSNNTIFGTQIKDFPKLDMPMVCDMSSDIFSRSLDFSKFDLIYAGAQKNMGPAGTTLVVVKEEILGKVTRQIPSMMDYQTHISKGSMFNTPPVFAVYVTMLTLQWLKDLGGIAAIEKENEKKAQLIYSEIDLNPLFKGFAEKADRSIMNATFTLENDNLKDTFETMVKEANINGINGHRSVGGYRASMYNAMPLNSVGILVDVMSELERKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN89</accession>
    <name>A0A5C6ZN89_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Bacillithiol biosynthesis deacetylase BshB1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">bshB1</name>
        <name evidence="1" type="ORF">ESY86_03550</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019213">
        <property type="term" value="F:deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071793">
        <property type="term" value="P:bacillithiol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023842">
        <property type="entry name" value="Bacillithiol_biosynth_BshB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003737">
        <property type="entry name" value="GlcNAc_PI_deacetylase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024078">
        <property type="entry name" value="LmbE-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12993">
        <property type="entry name" value="PTHR12993"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02585">
        <property type="entry name" value="PIG-L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102588">
        <property type="entry name" value="SSF102588"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04001">
        <property type="entry name" value="thiol_BshB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="238" mass="26755" checksum="E2C007E6B45B58FF" modified="2019-11-13" version="1">MKLDILAFGAHPDDIELSCAGTLAKEVANGKKVGIVDLTRGELGTRGTEKTRDEEAKDAAAILGVSIRENLGFADGFFINDKTHQLEVIRMIRKYQPEIVICNAIHDRHIDHGKASQLVSDACFLSGLTKIETQAEGELQEKWRPKQVYHYIQWKNITPEIIVDITGFEDTKMKSVLAYKTQFFNPESKEPQTPISSKNFSDSILYRARDLGRLIGVEYAEGFTADRHIAVDSLFDLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN99</accession>
    <name>A0A5C6ZN99_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_01675</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="158" mass="18826" checksum="FA7E41D3B00E0CA7" modified="2019-11-13" version="1">MKAVSVVSIRKELKHKSDAELAELCLRLSRFKKENKELLTYLLFEADDEQAYIETVKNEIDEQFEAINTNSFFYIKKSVRKILRNTKKYIRYSLNKETEVELLLYFCKKLKAMSPSIKRNTTLLNLFDRNMEAITKKILKLHEDLQHDYGLLVEELER</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNK2</accession>
    <name>A0A5C6ZNK2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Type I glyceraldehyde-3-phosphate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">gap</name>
        <name evidence="9" type="ORF">ESY86_05855</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020831">
        <property type="entry name" value="GlycerAld/Erythrose_P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020829">
        <property type="entry name" value="GlycerAld_3-P_DH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020828">
        <property type="entry name" value="GlycerAld_3-P_DH_NAD(P)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006424">
        <property type="entry name" value="Glyceraldehyde-3-P_DH_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43148">
        <property type="entry name" value="PTHR43148"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02800">
        <property type="entry name" value="Gp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00044">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000149">
        <property type="entry name" value="GAP_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00078">
        <property type="entry name" value="G3PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00846">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01534">
        <property type="entry name" value="GAPDH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gp_dh_N" evidence="8">
        <location>
            <begin position="2"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glyceraldehyde 3-phosphate binding" evidence="4">
        <location>
            <begin position="150"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glyceraldehyde 3-phosphate binding" evidence="4">
        <location>
            <begin position="209"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="11"/>
            <end position="12"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="313"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Activates thiol group during catalysis" evidence="6">
        <location>
            <position position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD90260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="338" mass="37097" checksum="37B044A6414592FE" modified="2019-11-13" version="1">MIKVAINGFGRIGRRVFRLIEARNDMEVVAINDLADAKTLSHLLKYDSIHGVSKQEISSKDGTIIINGREIPLSHDAHPKTIDWRMHQPDFVIEATGKFKQESDLNYHIENGAKRVILTVPPIEDSIKTVVLGVNEDILQGDETIISNASCTTNNAAPMIKVIKELCGVKQAYITTVHSYTTDQSLHDQPHKDLRRARAAGQSIVPTTTGAAKALTKIFPDLSEVIGGCGIRVPVANGSLTDITFNVEKTVSIEEINNAFKLAAKTHLKGILEYTEDPIVSIDIVGNTHSCVFDALMTSVIGNMIKIVGWYDNETGYSSRICDLICNLSMKSSRLSNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNM7</accession>
    <name>A0A5C6ZNM7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_06020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016769">
        <property type="entry name" value="Phage_SP01_Orf1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF020079">
        <property type="entry name" value="UCP020079"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="137" mass="15851" checksum="6914AD8567AD3C37" modified="2019-11-13" version="1">MNFLEKLVIAVDFDGTIVDDAYPRIGKPRIFAFETLKRLQKDGHRLILWTYRSGDRLEEAVQFCKDNGINFYAVNHSFPEEVYDGNISRKINADLFIDDRNIGGVLGWGEIYQLITKEEPDLSSVKPKKGLFSFFRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPQ8</accession>
    <name>A0A5C6ZPQ8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyltransferase family 9 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_04540</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03789">
        <property type="entry name" value="GT9_LPS_heptosyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002201">
        <property type="entry name" value="Glyco_trans_9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01075">
        <property type="entry name" value="Glyco_transf_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="351" mass="40258" checksum="80B716A12A5E8EBE" modified="2019-11-13" version="1">MKILIIQQKMIGDVLTTSILFEALREKFPKAELHYVINSHTFPVVEHNPFIDKFLFITPEIEQNRLKFLSFSRTIQKEKYDTVIDVYGKPSSILMSAFSKAKKKIAYHKKHTSFIYSHAIKRKSTPEYAASLAVENRMLLLKPLGIDFKNIQPKIYLKEDEITSAKNYLETNDILLNQPLFMIGVLGSNPSKTYPFEYMAKLIETVAQTKNAQILFNYIPTQEEEAKAVYELCKASTQEQIHFDVFGKSLREFLAILSQCDAIIGNEGGANNMAKALNIPTFTIFSPYLNKHNWFGENEEVQNVAVHLSDYIDLQASDVKQAKKQSALYYEKFKPSFVKSKLEAFLSTFSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPR1</accession>
    <name>A0A5C6ZPR1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Rhomboid family intramembrane serine protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_00660</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="SSF144091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="176"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="217"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="243"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="Rhomboid" evidence="6">
        <location>
            <begin position="44"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="Rhomboid" evidence="6">
        <location>
            <begin position="170"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD91331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="273" mass="30963" checksum="199B738D838B26B6" modified="2019-11-13" version="1">MRGITDSVKHLIIINAILFIGTMAVGNNLFYDWFALHFPKNDMFQPWQIITHMFMHGNFMHILFNMFALWMFGTAVEQVLGSKKFLFVYFSAGLGAVLFQLGFYYVKYYFAFDGIQGLGMTSQMIHEIVNINAIDGQYIKPTLFEKGLYPILNNFNFNADLINQNAFISLFEMNNIVAASMVGASGCIMGILAAFGMMNPNAKLMLIFLPIPIKAKYFIPGIIALDVISAISGQSFFSPSNTAYMAHIGGALTGFIIMWYWKRTQFNQNRWDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPZ1</accession>
    <name>A0A5C6ZPZ1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">2-(1,2-epoxy-1,2-dihydrophenyl)acetyl-CoA isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_01925</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the enoyl-CoA hydratase/isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.12.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018376">
        <property type="entry name" value="Enoyl-CoA_hyd/isom_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014748">
        <property type="entry name" value="Enoyl-CoA_hydra_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00166">
        <property type="entry name" value="ENOYL_COA_HYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="260" mass="28348" checksum="5F6255D6A6D71D99" modified="2019-11-13" version="1">MSNSIEVKIENKVATIRLNRPEVFNSFNREMAFLLQDTLDECEKNAAVRAIVLTGNGKAFCAGQDLKEVTNPDLNPGFKKILEEHYNPIITRIRAIKKPIIAAVNGVAAGAGANIALACDIVVAHDKVSFIQAFSLIGLVPDSAGTFFLPRLIGFQKALALALLGDKISAEEAEKMGMIYKCVPTEEFETTINALALKLANMPTKALGLIKELYNQSMTNDLEAQLALESKLQIEAASTEDYAEGVAAFMEKRKPEFKGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZQ32</accession>
    <name>A0A5C6ZQ32_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Gliding motility-associated ABC transporter ATP-binding subunit GldA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">gldA</name>
        <name evidence="5" type="ORF">ESY86_02135</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019864">
        <property type="entry name" value="Motility-assoc_ABC_GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03522">
        <property type="entry name" value="GldA_ABC_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="3"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="35"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="297" mass="33370" checksum="046C71B289034287" modified="2019-11-13" version="1">MSIEVENISKVYGEQRALDHISFKINKGEIVGFLGPNGAGKSTLMKILTTYSSASEGFAIVTGKDVVTNKQAVQQSVGYLPEHNPLYLDMYVKEYLNFNAGIYKVSKARIAEVITLTGLTPEVHKKIGQLSKGYRQRVGLANALLHNPDVLILDEPTTGLDPNQLVEIRHLIKNVGADKTVFLSTHIMQEVEAICDRVIIINKGQIVADKKLKDLRDDTEQTVIVEFDYRVEDAFLLRLPKAKSVKNTHDFTYEITFATSDDMRSKVFDFAHDNELKILQLNQKNASLESLFRELTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZQ94</accession>
    <name>A0A5C6ZQ94_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TrmH family RNA methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00405</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004441">
        <property type="entry name" value="rRNA_MeTrfase_TrmH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46429">
        <property type="entry name" value="PTHR46429"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SpoU_methylase" evidence="1">
        <location>
            <begin position="17"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="166" mass="18646" checksum="3DBFE1CC8226DFB8" modified="2019-11-13" version="1">MQLDHHSTNFTSKKFPITLICEQVGTAANIGSLFRTADAFGVEKLIFCGKEIPMGRKMTKTSRATEKYVDYEVSENIQEKLSDLKQKNYFLVALEITEASHDLKSFEFPKQKRIALVIGEENFGISEAVLQQMDAVVHIPMFGQNSSMNLVQASSVALYEITNQMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZQG0</accession>
    <name>A0A5C6ZQG0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="64" mass="7151" checksum="6B74AEF899F4817E" modified="2019-11-13" version="1">MNISKTLSYVMILIGAMVAIYAKAQVNQNEYILIGGIVLLMVGVYRISRNISSKSERENDNESQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6Z8W8</accession>
    <name>A0A5C6Z8W8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20685</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000103">
        <property type="protein sequence ID" value="TXD85980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD85980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="104" mass="12084" checksum="432E6B5605AD6312" modified="2019-11-13" version="1">MIHNPRQREDVGGKHQHRQLDHEQNSTQVYGFKASRFENKQARFNRDTGSSEAIVGVFHQQSQPSETKDNLNRNHEFSEAIVGVFHQQSQPSKTKAHINYQMQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAQ9</accession>
    <name>A0A5C6ZAQ9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000050">
        <property type="protein sequence ID" value="TXD86585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="174" mass="20651" checksum="0815AC80D08CBF2A" modified="2019-11-13" version="1">MAGLGFIFIVLPISVTLFLLWILTKKKFFGIALIGMWVGMISLWILSAILQPFYAKKVLDKSDFYGEYVIDREYFAGNQADWQYNNFRFEIKENDSIYFYVTNGKIINETYKGTISTLAPYQSARLVIEMEKPTHHILTTNPTIYREIWDFFMVFNSPKFHNMYFRKGEWKEIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAR7</accession>
    <name>A0A5C6ZAR7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_19800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000048">
        <property type="protein sequence ID" value="TXD86596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022922112" evidence="2">
        <location>
            <begin position="26"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="257"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="388"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="388"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="557" mass="61949" checksum="47761ED89C64AA48" modified="2019-11-13" version="1">MKNKRIKNYLKFGILLFGISVIVIACQKDDNVSTEQNSERKIPQIETISYDDANTTFSNLKAQYNLDRYKATKFAGNIQAKSTTDTLGLIIETDIIKQATLGDYTSYTMKIVHQNDSTVFYNLTIEYKNGESAMFITKYTPTEYWLNNKGEVYQGEVQSKSATLTQYTDPEDAFEEGYTGNPELGSGPGGGGGAIYDANYPSGCLGTVIATTAYEAYPCDCGHMPWDNTCQGCTTNPKWPGFEEVIMYTCEESWDINDPYDPGDTGNPGGGSLPDPTEDDPSITVTIRPEECTERVTGDLDGDCALDAYELCLLNGNDQEVCDCVADGNELLDCIEPKTDCESLSLLVANDSLGSNILPIVNQLRTKLGTNDNEWSISYENVWSEDGRKNVPDTEDGIREGTSRTRSKSKSGNLWVGQIHTHPLNTYKVFSWLDLRALKLIYEDVNNHFKQDVFLMAVAPNNETYAMKVNDIAALISKIDADWTNASGTTNQEKESDIEKVMVDKYSISSNQEQAFLELYGDYGISFYKATDANLSNWKLLELDENNNQTVNETPCN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAY4</accession>
    <name>A0A5C6ZAY4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">GLPGLI family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19575</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000043">
        <property type="protein sequence ID" value="TXD86691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005901">
        <property type="entry name" value="GLPGLI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09697">
        <property type="entry name" value="Porph_ging"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01200">
        <property type="entry name" value="GLPGLI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="276" mass="32067" checksum="C3C9A24A9F7E240A" modified="2019-11-13" version="1">MKLRTAFFLNTNKMKFITLIVIITFNTILHSQSQTGLVQYGHKQSMGMGAPIGIDYNANLIFDNENSLYTFAKDSLEGGHIRESVYIEKDKDNFFVNSKITNKLGFQYYVDKENKKLLSRDIGFNYVKEEIPTINWEISDEKKDIGSFECLKASTEFRGRTYTAWFTTSIPLPYGPWKLQGLPGLILEAYDTNKEIYFYFKSIKYPMDSKIKIQKPNSESENKEWITFSEYKKTLINKHKKAIENGRMLIEGFDSADTAEDKYTMGNSYIEIFDNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZB26</accession>
    <name>A0A5C6ZB26_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_19435</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000040">
        <property type="protein sequence ID" value="TXD86746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="208"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="241"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="556"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="605" mass="69153" checksum="FAB0CCCFC9B07D2E" modified="2019-11-13" version="1">MNNITIIEFLLVGLIILIQIIQTLKTFKKINVLKSIIPNKEFFKIKLFNIPVEDLQVFQPQDVLDNLSKYELETSDSNSKPIADDFEYIYENLERLTITEIKDRIKVNFSENIKATLKEEIIDEAIAIHNYYENYDNSNQQNSVINEISLINPNETSNSIFEGLLHSINVYLLRNKGATTDFNLIKDITERNIDTEDEDISQRITTPLYLGLMGTMLGIIFGLINLFLVSGKGDEFEIQGFLIGVSIAMSASFIGLLCTVLNSTYYKTARKNVEVSKNDFYTFIQTELLPILNQSVSSSVFMLHTNLVKFNDNFTVNINRLTGLLNKNYDAVIAQDKILQSLEKIDITEFAKANIKVLRELKAGTEDLHKFNQYLSSLNSTVDGTTRLSNSFQILLNKVNNFEGLAEKLDSRIEESNKLVQFLNDHYEVLNERGDLLTDSVKKVDDVLNKSLVELREHTREKIDAIKEITIKEEDLMTKSSSKRIKTLEELSELEKNLILKGFQEKIDSIKDLTKTEKELMEKAFSENSRSLSKLNILENLNESINVIKTNSNRQIDSVKLEINTLKESMDKANKILSEINNKNLTQKNNTIATSIKNIFSSKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZB76</accession>
    <name>A0A5C6ZB76_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF3857 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_19190</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000037">
        <property type="protein sequence ID" value="TXD86818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024618">
        <property type="entry name" value="DUF3857"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002931">
        <property type="entry name" value="Transglutaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12969">
        <property type="entry name" value="DUF3857"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01841">
        <property type="entry name" value="Transglut_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3857" evidence="3">
        <location>
            <begin position="92"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="TGc" evidence="2">
        <location>
            <begin position="291"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD86818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="653" mass="76104" checksum="B1711619943DAAC0" modified="2019-11-13" version="1">MPTETPTIQKVECSYWVWVLMAFLYLPFQSFAQYSPEFELNKSMYPESSKVRLLDEVSISVKLKNDALEIEQSYIEEDLFLDESATYGSKKALSFSSFFELRSVEATSYEYKNGRYDAHKVEDFVEKDEMNDAFHDDTKSLNFIYPNLSVGGKTKLSYSEIVKNPRFLSPIYFGDFFPIQHKKVTLVADKEIQFEFKEFNTEAYDLVFSHEEKRGNIIYTWELKNIKKFKYEDNIPSYNRLLPHIVPIISSYSKDGKTVNLLNGVADLYQWYYSMVKDINLQAPDANLVTLVSELTKDKPSDIEKVRAIYYWTQKNIKYIAFEYALGGFIPREANDVYNKKYGDCKDNSSLLFEMLKIAGLDGKLTWIGTRTIPYRYSEVPTPLVDNHMILSIEIEGQTCFLDATGRYLPLEMPSSFIQGKEALISRSATEYDIKTVPVMSPKTNSLIERMTLKLEGQMLLGTSQAEISGYYKIDFFNQLEAENTSEKINAYYTAKLQKGNNKFLINELSETNKFDYDKHLLVDYSFNIADYAKIYNDEIFINLNLSQNISVYKTEDDRQNDTEVKYKSYYDYENILEIPDTYVIDYVPDSFSMHNAYFDCEITYEVSSTNIVYRNKLEMKFLNLNPKQQKEVNTAIKMVEKNFKEIVVLKKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBA0</accession>
    <name>A0A5C6ZBA0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19555</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000043">
        <property type="protein sequence ID" value="TXD86687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="158" mass="18347" checksum="20784266B5337602" modified="2019-11-13" version="1">MKKPIYISLICIILTSCSVNKTISEIKNYVKEIDNRTDLNESITEFNTENLRGEIIGGTSTYELTDKKNKLYRIITETAQPNDSTAYFEFYYKEKKLVFAKVLQFSNTETELDTITNTELYFHKEKLIKQIDFKLNKINSEKIKLLAESYTVEGLGTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBK5</accession>
    <name>A0A5C6ZBK5_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Proline--tRNA ligase</fullName>
            <ecNumber evidence="7">6.1.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Prolyl-tRNA synthetase</fullName>
            <shortName evidence="7">ProRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">proS</name>
        <name evidence="9" type="ORF">ESY86_17085</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro)</text>
            <dbReference type="Rhea" id="RHEA:14305"/>
            <dbReference type="Rhea" id="RHEA-COMP:9700"/>
            <dbReference type="Rhea" id="RHEA-COMP:9702"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78532"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.15"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">Consists of three domains: the N-terminal catalytic domain, the anticodon-binding domain and the C-terminal extension.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.15" evidence="7"/>
    <dbReference type="EMBL" id="VORO01000025">
        <property type="protein sequence ID" value="TXD87386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004827">
        <property type="term" value="F:proline-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006433">
        <property type="term" value="P:prolyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00778">
        <property type="entry name" value="ProRS_core_arch_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01571">
        <property type="entry name" value="Pro_tRNA_synth_type3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004499">
        <property type="entry name" value="Pro-tRNA-ligase_IIa_arc-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016061">
        <property type="entry name" value="Pro-tRNA_ligase_II_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017449">
        <property type="entry name" value="Pro-tRNA_synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033721">
        <property type="entry name" value="ProRS_core_arch_euk"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43382">
        <property type="entry name" value="PTHR43382"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09180">
        <property type="entry name" value="ProRS-C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00946">
        <property type="entry name" value="ProRS-C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64586">
        <property type="entry name" value="SSF64586"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00408">
        <property type="entry name" value="proS_fam_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="8">
        <location>
            <begin position="27"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD87386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="492" mass="55901" checksum="E8E863D9D176A148" modified="2019-11-13" version="1">MSKNLTSRADDYSKWYNELVVKADMAENSAVRGCMVIKPYGYAIWEKMQAELDRMFKETGHQNAYFPLFVPKSLFEAEEKNAEGFAKECAIVTHYRLQNDPDNPGKLRVDPEAKLEEELIVRPTSEAIIWSTYKGWIQSYRDLPILVNQWANVVRWEMRTRLFLRTTEFLWQEGHTAHATKQEAIAEAELMNDIYAEFAENFMAIPVIKGIKTESERFAGAIETYCIEALMQDGKALQAGTSHFLGQNFAKAFDVKFTNKEGQLEYVWATSWGVSTRLMGALIMTHSDDKGLVLPPNLAPSQVVIVPIYKNEEQLELITEKANGIIKGLKLKGISCKFDGRTTHRPGAKFAQHELQGVPLRVAIGPKDLENNTAELARRDNLTKQIIGFDDLERTVETLLTTIQEELFTKALNFRDSHMTKVDDFEEFKKVLDKKTGFISAHWDGTAETEQKIKDATKATIRCIPMDAKEELGTCVFSGKPSKQRVLFAKAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBW0</accession>
    <name>A0A5C6ZBW0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">AI-2E family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_18725</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000033">
        <property type="protein sequence ID" value="TXD86963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002549">
        <property type="entry name" value="AI-2E-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21716">
        <property type="entry name" value="PTHR21716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01594">
        <property type="entry name" value="AI-2E_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="59"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="139"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="198"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="225"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="258"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="289"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD86963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="345" mass="39124" checksum="ADD38318E79FE92C" modified="2019-11-13" version="1">MLEQRRTTNLLLLIIVIPLVFYLLKTLSFIFIPLISSMFIALLFLPLMRWLGKRKVPRLFSIVIVLALIVLAVFIGVELVQLSSKQIMASDSGFFAKAEVKINDLMGYLQKEFGIAYNQEGSILGQFFEKDNIGSTVDFLRKFLTTILMIIFFTVLWLAESINMQRVLNDTILRRKHTSVKAFMKIENDLITFIKVKFAVSLLTGIFTGLACVFFDVSFPIFWGLFAFLINFVQMVGSFISVICLTIFAFVELETSSVLFFFFLSITGVQVLFGAILEPVFMGKSFSINVIAVLIMLMLWGYIWGIPGLIMAIPITVFIKIILEQFPETKVVASLLSGSERTLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZC10</accession>
    <name>A0A5C6ZC10_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aspartokinase</fullName>
            <ecNumber evidence="3">2.7.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_18785</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>ATP + L-aspartate = 4-phospho-L-aspartate + ADP</text>
            <dbReference type="Rhea" id="RHEA:23776"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57535"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 4">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 1/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 1/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the aspartokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.4" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000034">
        <property type="protein sequence ID" value="TXD86917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00015"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00461"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00462"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004072">
        <property type="term" value="F:aspartate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001341">
        <property type="entry name" value="Asp_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042199">
        <property type="entry name" value="AsparK_Bifunc_asparK/hSer_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00657">
        <property type="entry name" value="asp_kinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AA_kinase" evidence="5">
        <location>
            <begin position="3"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD86917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="416" mass="47079" checksum="7033458DDD1507FF" modified="2019-11-13" version="1">MRIFKFGGASVKNAEGVKNLASVLQQVGHEHTLVVLSAMGKTTNALEVVIHNYFNTKPELQSALQEVKSYHNGIVLDLFEHTEHPVFKKVAALFQDLDYFLNRNKSPDYNFVYDQVIGYGELLSTTIVSAYLNAIGLTNTWLDVREFIKTDDYYRTANVEWDITQAQIRAKFNPEVLNVTQGFLASDANNFSTTLGREGSDYTAAIFAFCLNAESVTIWKDVPGVLNADPRYFENAQLLNVISYREAIELAFYGASVIHPKTLQPLQQKEIPLYVKSFLNPKNPGTMVGKASGIDPQTPCFIVKKNQVLVSLSSLDFSYIVEENISEIFRLLHLYKMKVDVIQNSAISFAVCFENTYNNLDKLIQHLKAKFKVNVYENVNLYTVRHYNEQAIASVEKGKELLLKQLTQETLQIVTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCK3</accession>
    <name>A0A5C6ZCK3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF1016 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_17755</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000028">
        <property type="protein sequence ID" value="TXD87161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009362">
        <property type="entry name" value="YhcG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041527">
        <property type="entry name" value="YhcG_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17761">
        <property type="entry name" value="DUF1016_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06250">
        <property type="entry name" value="YhcG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1016_N" evidence="2">
        <location>
            <begin position="10"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="YhcG_C" evidence="1">
        <location>
            <begin position="166"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06250"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="331" mass="38979" checksum="866648E3628905A3" modified="2019-11-13" version="1">MELQPQFEHIAQLIEQAKRRAFKQVNTEIIDLYWNIGAYLHHQVNTENWGKSVIKQLATHLKNRQPSTKGFSAQNLWRMKQFYETYKDAEKLSTLLREIPWSHNMTIISSAKSAEEQEFYIKLVIKERLSFRELERQINSSYYERVMLGNTKLSTLSREFPEDVSNIFKDTYVLEMLQLPVSHSEKELKLKIAQNISQFLLEFGRDFAFMGEEYPLQVGQQDFAIDLMFYHRTLQCMVAIELKIEKFRPEFLGQLNFYLEALDKDIKTETEKPSIGILLCKGKDDTVVEYALNRSLSPTLVADYKTQLPNKKVLKQKWQEILNQLDTTKND</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCK8</accession>
    <name>A0A5C6ZCK8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_19410</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000040">
        <property type="protein sequence ID" value="TXD86741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="511" mass="59022" checksum="1BA618A3A191E9BC" modified="2019-11-13" version="1">MKKNITKPKQKRLSIFSVLFLFGILLFFNSCDDEPIDELNKKINIALRSGNEITENERNEFIEYINENSLDLPQIIDSNNEINQEELTNLILSVANKRRNNTEPKIFSPNNNSENEDKNTIVSVFIENSGSMDGYVQGTTEFEAALSDLLVQLQYKYNKEKNNNQNLNINFINTKIYPSKVDEVNNFVETLEPSKAPYKVGNRSVSKLNEILEIILDSTKQNEISILTSDCIYSLDKGKDTEGALEFQKSLTKGAFLEKSKEFDFSTIVLKMNSKFDGYYYDKDNNKTRLSKKERPYYFWIIGKHNLIETFQKEINLKQLKGFENSYYLSNSQENNQPFFTVLKETNKIGNYKPTDRKAKDLKSINEIEYENGNLQFSIAIDLNNIPVDKTYLTNSESYIVPDGFIIKSIEEVDRNKIEDRDFVTVEKTTATHIITIATSNKFTLQDLKLELSNKIPAWVEESNSIDDRDVENELDKTFGLLYLVQGVSEAYTTQNPNNKSYFNINIEIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCU3</accession>
    <name>A0A5C6ZCU3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">TlpA family protein disulfide reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_16400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016209">
        <property type="term" value="F:antioxidant activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="14"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="173" mass="20088" checksum="B1BB64F082FE95EB" modified="2019-11-13" version="1">MRYLFLLILVTCVCCKNTQKPEVALTAPIENPVGDALEVYDFEEFESLLHKKDNYTYVINFWATWCAPCIKELPHFEQLNAQYADKNVKVILVSLDFPNQYDFRLKPYISSNGIKSKVVALNDPDSNSWIPKVDKNWTGAIPATLIYNDQKRTFYEQSFDYDQLQTAVKPFLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCW6</accession>
    <name>A0A5C6ZCW6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GLPGLI family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_20040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000055">
        <property type="protein sequence ID" value="TXD86504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005901">
        <property type="entry name" value="GLPGLI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09697">
        <property type="entry name" value="Porph_ging"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01200">
        <property type="entry name" value="GLPGLI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022699624" evidence="1">
        <location>
            <begin position="20"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="268" mass="31437" checksum="43B46C6019F0A6D0" modified="2019-11-13" version="1">MVQKFIFTLIFLASIIANAQKKYSIQHKFTYKLTYQPDSTDVHTKQSEDMFLLTNEDLSIFQSKNGYIKDSLLLAIENKPAQEINMLDISRFPKTQFHFKILKEKSEDSITVYDKIYTDNFQYKESNNNIKWEITSETLSINGLKCQKATAYYAGRNYEAWFSNEIPISDGPYKFSGLPGLIIKISDLKNHYVFELIAKSDKNLSYSSLKPRRNLFITTKSIYFDRLKDYKKNIVERIAQSGFTINDEYKEEVKQKLKKRNNPIELKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCY6</accession>
    <name>A0A5C6ZCY6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycoside hydrolase family 16 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_16035</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000021">
        <property type="protein sequence ID" value="TXD87666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="GH16"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH16" evidence="2">
        <location>
            <begin position="29"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="274" mass="30948" checksum="7BA3C9C2C4F65E52" modified="2019-11-13" version="1">MKSIFTGCIAIISIGLLSNCSSDDTQTVTTFDTLIIEDNFDIDGAPDPNLWGFDIGDGSDQGLDRWGNNELQYYTDRTENVKVENGFLLITARQEDFQGSNYTSARLVTKGKFDQKYGRFEARMRLPYGRGMWPAFWMLGDDNDGVDVWPQIGEIDIMENRGQEPTIITGSVHGPGYSAGNAVSKSFILDGARFDTDFHVFGIEWGPNYINYYVDNKLYNQITPADVDGEWVFNDRPFYMLLNLAIGGSYVGNPNDETNFPQTMLVDYVRVYQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDG1</accession>
    <name>A0A5C6ZDG1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AAA family ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15725</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="676"/>
            <end position="703"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1494" mass="174966" checksum="2C3B35E7C8F05624" modified="2019-11-13" version="1">MKQDLYANRALDFNKLDHREFEEVVYHYFKDQIDKDLYYGIYDNVELSSSVGERGADAMLFLDGKITGIVQCKKYKSNLTIDLVLSEIIKFLLYHILETQLSNKNTSSLINDIKDFSYYFVVSKDFTQATKLLLASFNQKWSTKNIPSIISKVTSVKSFEKLNIEKAQEQLKELLNSINVVPITAVDLDPIVRINPYLKNRYFSPQSLVGKEQKDIFIKQNNTNEDDSISKEFAVKKTELISNDITRVKSFFGKNELLKIKRAETEEIFEWIQQKPKENELNIAVVAGNAGMGKSVILSQLYSKLKSENIPVISLKADRLIFNSIKDLESEYNLDVSFEKLFDRLIESDKTGVLLIDQIDALSQALSSDLKPLKFYDNLIQRFTSHPKVKIVISTRIYDLNYDPIISNYKGKKSFIIRALKRDVLIDVLKRSGIEKVGQFTEAFLELIAVPLHLDVFLKVYSESLKVKEIKSLQDLYSQLWKQKILEAKRFNITAVNPENLSDFIFKVALKMYDLQEINLDARLFEDQYFKEIKFLKSEGILVDAKNIEFFHQSFFDYAYARNFINGEKDLLTDILNRHQGLFVRSKIKQILNYKSSVLHHEYVSDVNKILQHKEVRFHIKLLILQEIAFQESPTIAEQNTVEHIVFADDELKSAFNTSLMDQGWLSFFINRDIFREDIENNNDELKTQITSSLRRVALAENNENLLKYYKTLKDSSIKDELIIDYLWQIGEVKSELAIELIENVFSRKKEYSKQYWFYSILENTSTNFPTWTAKNLREHIDIVKGTDINDDKNYFYTQHLGGRIYEKLWAKHPDVAYTLVKDVITEIISKRKFERNGIIELDSAFLLYDRKNLDLYKHNKQLDILQTYLEGKFITDPNFVRDEVNKYLDSNRIVYIIIGFSIIFKYPKEFKNEAYPFFSDTTKLEELYSLNRYLNYMMLEVFGQMYHVLNDEEKNKIEDILLSNFRKRVELRVIINDDGSKRKNKYYGIGKYELLNSINDKGKMPKHLKKDYLELFRKFGAIKNEEPEGTVVFVNRDPLGNPEYDKFSLEDWRNSFKTYTHTNKNYNSWNQPAEYEHGRKFVTVVSEEPNKFIDFVYNIIDDSEISNTYIVKALEGLKEGGIDVDKLKDVFLYAINQRKYEKENTLYLIWVTRYFTDKKKVYPEILDYLKLQIVSGDEGRENLNDALSTGINSIRGAAASSLVDYSFSNKTFNFVCETLQLLVDNSRPSTRASAIYKLQYLLKYGKEEILNLFLGLAKDYDAGVLKISINPLQYLVHYNFERLIPFFESALQVKESNKEIGKLITIGYCNNYVEADDLLESFLKHNEPNSIIKTAFEFIENGHKVEMALTLVMRFLDLESKEVGEIYNRAFFHLKPKQFKKLRTFLFEYVESSVGKWREYPFYDFLLECSGEHYDDCINLAREYKNHYEPNVTQRGLQNAPLKVIISSYNAVREYDKSNPILDKAMDIFDDMLKNEDYINASAHQILKDVDSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDW5</accession>
    <name>A0A5C6ZDW5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000036">
        <property type="protein sequence ID" value="TXD86868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="81" mass="9305" checksum="1AA28697E74A0B2C" modified="2019-11-13" version="1">MKNSETIIKIVLAIVLFLCLLDMPYGFYQLVRFMALIGFGILAYKANEQNKNTEMIVYGGLTLLLFSTILKVNIHKLFIFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDX7</accession>
    <name>A0A5C6ZDX7_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">HTTM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_17440</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000026">
        <property type="protein sequence ID" value="TXD87344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011020">
        <property type="entry name" value="HTTM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023894">
        <property type="entry name" value="Sporulation_SdpB"/>
    </dbReference>
    <dbReference type="SMART" id="SM00752">
        <property type="entry name" value="HTTM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04033">
        <property type="entry name" value="export_SdpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="134"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="198"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="228"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="HTTM" evidence="6">
        <location>
            <begin position="1"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD87344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="289" mass="33780" checksum="BF023F833B734A04" modified="2019-11-13" version="1">MTLTSYNIARTFLAFGLLITLIFNSNYTLFGYDILHLNNPVFDYNFYYILREHLVLAKILSIIILLIVISGYFPRYSGILHWYITYSFFMSSDVADGGDHIASNITLLLIPLTLLDNRKNHWSHQIVSQGNLKLYLMNSIYFLIAIQICAIYLHAFIGKLFVEEWKNGTAIYYWMTHNHFGINPIFKDFATQLLSNKFIVIIISWSTLALEFLLASCIILSQSNKKRYIFLFSGILFHFGIMLIHGLVSFFFIMSAALFIYLMPKHSQFSLNQLKNKKIWKQFINQFLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE48</accession>
    <name>A0A5C6ZE48_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_14245</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="43"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="102" mass="11653" checksum="7D2B0D2DD9CEE0B3" modified="2019-11-13" version="1">MKAKNKNLKSLDQFVDEKIGKKGTVKREEFETEYDAFKLGVLIQQAREDKGLTQEQLAELAGTNKSYISKLERNLKDIRFSTLQRIINDGLGGHLDISIRLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE97</accession>
    <name>A0A5C6ZE97_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase family 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_16865</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000024">
        <property type="protein sequence ID" value="TXD87450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="295"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="9"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="325" mass="38828" checksum="10DB94D4346F69E2" modified="2019-11-13" version="1">MSVRSLLVSIIIPTYNRAHLIGETLDSVLAQTYTNWECIVVDDGSTDGTEVLMKTYCDKDSRFQYHHRPAGRLPGGNAARNYGFEFSKGEYVKWFDSDDIMHPNFISKQYLILSEKPSLDFCACQWEYFDDVGQIKKVYINLKPQNESIYSYFLEGHVFLTHAPLWRKSFLINCELFDEKLKRGQETDFHFRILTKNPKYLIHEDFLFQVRRNHKSIESTSNNIVPQESVLIYFKKVFFILKEIDFDKKEVVRSYIWYRCVNQIGILMSKQKSILGRWKYFRGLNQFYSKRTDFYIIYLFLFVALITNRGYYFYSLKKYDLRKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEB1</accession>
    <name>A0A5C6ZEB1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sigma-54-dependent Fis family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_13350</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025943">
        <property type="entry name" value="Sigma_54_int_dom_ATP-bd_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01590">
        <property type="entry name" value="HTHFIS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00676">
        <property type="entry name" value="SIGMA54_INTERACT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Response regulatory" evidence="7">
        <location>
            <begin position="7"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="6">
        <location>
            <begin position="145"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="5">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD88290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="447" mass="50425" checksum="0A042979E4B50180" modified="2019-11-13" version="1">MLLQNSKILVIDDDEDVLIALRLLLKSKVKEVVTNNNPNNILNLMQQHAFDVVVLDMNFNGLVNTGNEGIFWLNKIKKQSPEVDVILITAYGDIDLAIRSLKEGAADFLVKPWQNEKILDAIRERIEKQKKQGPKKLHLNADTKIIGDSEAMQDVFVKLKKVAPTDANILILGENGTGKDLIAKAIHDNSLRKHKPFVKVDVGALTETLFESELFGYKKGAFTDAREDRKGRFEAANGGTLFLDEIGNISLRQQARLLTVLQNRQVTPLGANQSISIDIRLICATNVSIRDLADEGRFRKDLIYRINTVDMTIPPLRERGTDMTILAHYFIDFYAEKYGKGNFSLSASFIQKLKKHHFSGNVRELQYALERAIIMADQDLLEAEDLTFSAIEQPQVRATENETNLDALEKNTILNVIEKNNGNISKSAKELGITRAALYRRLHKYDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEB6</accession>
    <name>A0A5C6ZEB6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2975 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_13685</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021354">
        <property type="entry name" value="DUF2975"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11188">
        <property type="entry name" value="DUF2975"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="169" mass="19309" checksum="F59F3075E059D5A6" modified="2019-11-13" version="1">MRKLTILKSLVDFIWIITCIPLIPILLFFAVYIFINDEAISLFINSGDGAMDFSSVWTKVFLILLFVLIYVVIYCVYLFRKTLRTFQQRKPFSTAVIDNFNTIGKLLVISGISFSLLVFSYKLVFKAKFEISLGVTPYLGIVCLGLFFLVLSEVFKIAKTAKEENELTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEC1</accession>
    <name>A0A5C6ZEC1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_13405</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="76" mass="8975" checksum="D2745E5C2BEDDCFB" modified="2019-11-13" version="1">MDRIVIEVSEETAKKWRLSSPEKRERISQRMNIRLNQELLKDSPDDFKKFLDEIGKTIEESGLTEKILQEILAEND</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEM0</accession>
    <name>A0A5C6ZEM0_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Transcription termination/antitermination protein NusG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">nusG</name>
        <name evidence="9" type="ORF">ESY86_16295</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Participates in transcription elongation, termination and antitermination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the NusG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000022">
        <property type="protein sequence ID" value="TXD87592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006354">
        <property type="term" value="P:DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032784">
        <property type="term" value="P:regulation of DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00948">
        <property type="entry name" value="NusG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006645">
        <property type="entry name" value="NGN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036735">
        <property type="entry name" value="NGN_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043425">
        <property type="entry name" value="NusG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001062">
        <property type="entry name" value="Transcrpt_antiterm_NusG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30265">
        <property type="entry name" value="PTHR30265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30265:SF2">
        <property type="entry name" value="PTHR30265:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02357">
        <property type="entry name" value="NusG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00338">
        <property type="entry name" value="NUSGTNSCPFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00738">
        <property type="entry name" value="NGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82679">
        <property type="entry name" value="SSF82679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00922">
        <property type="entry name" value="nusG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 5 6" id="KW-0889">Transcription antitermination</keyword>
    <keyword evidence="3 5 6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1 5 6" id="KW-0806">Transcription termination</keyword>
    <feature type="domain" description="NGN" evidence="7">
        <location>
            <begin position="7"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="KOW" evidence="8">
        <location>
            <begin position="131"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD87592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="185" mass="20785" checksum="4A3AFF728C0FBD94" modified="2019-11-13" version="1">MSETSVNKKWYVVRAVSGQENKIKSYIENEVTRLGLEDFVDQVLVPTEKVVQIRKGKKINKERVYFPGYIMIQANLSGEIPHIIKSITNVIGFLGETKGGEPVPLRQSEVNRMLGKVDELAVDADSNAAIPYIIGETVKVIDGPFNGFDGTVEKINEDKRKLEVMVKIFGRKTPLELSYMQVDKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEN7</accession>
    <name>A0A5C6ZEN7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">(4Fe-4S)-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_12975</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010693">
        <property type="entry name" value="Divergent_4Fe-4S_mono-cluster"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06902">
        <property type="entry name" value="Fer4_19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fer4_19" evidence="2">
        <location>
            <begin position="9"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="94" mass="10661" checksum="78F665ED4D4BA59E" modified="2019-11-13" version="1">MKTIPNVFSNADITVTYNPSQCVNAERCAKELSAVFRNSVIPWIDLDAASTDLIVKQINRCPSAALKFQWRRERIQKTQPSKHPSSRKETIPFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZEZ0</accession>
    <name>A0A5C6ZEZ0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hydantoinase B/oxoprolinase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_12875</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003692">
        <property type="entry name" value="Hydantoinase_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045079">
        <property type="entry name" value="Oxoprolinase_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11365">
        <property type="entry name" value="PTHR11365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02538">
        <property type="entry name" value="Hydantoinase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydantoinase_B" evidence="1">
        <location>
            <begin position="5"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="559" mass="61179" checksum="A47D223C2AA0784F" modified="2019-11-13" version="1">MGLNKFTSDIIQDSLISIGEAMFETIQRTSMSPIIYEALDYAVGITDGEGRLLAQGNGVITFLAAMSLVVEETLERFGEDNPLKEGDVIMANTPYVGGGTHLSDIALITPIFYKGERVAFTVNKAHWTDIGGTNPGSVSTVSTEIYQEGMHFPFIKIKEEGKINEAIVKMIEANVRLPKSTLGDLFSGVAANEVGAERIIKLIDKYGLEAYKQAAEEFMEYGERISLKELKKIPNGVYENTGWIENDGFGNGPFPIKLKITISDENMTCDFTGSHEQLKGPLNLSRTGLETAVRAAFKSITTPTLPANNGSFKHVKLICPEKTIVSAEAPAPISVYYEVFLAAIDLLLKTLGPVVPDKLPAGHFRSVCVTYISGIHPVTNEFYVQAEPLSGGWGACATHDGNRGQFSYAHGESYNIPAETRERKYGVVVEEYAFHNEGGGYGEFQGGNGQYLTFKILSEEAFLTGAFLGYSIPTWGLFNGKEGSYNYFTVIRTDGTEETYNVVTNVKLHKGDRVKLVTATGGGYGNPKNRPIEKIQRDLKNGFITKDQALEHYPKMAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF12</accession>
    <name>A0A5C6ZF12_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mobilization protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15855</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000020">
        <property type="protein sequence ID" value="TXD87784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043766">
        <property type="entry name" value="DUF5712"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18976">
        <property type="entry name" value="DUF5712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="217"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="343" mass="39361" checksum="7D9AEE894A21F403" modified="2019-11-13" version="1">MYITITPQKLGANYSQSSANFVGYLEKENEGLEQRDMEHFFNQYGDEIPAEEVVKEIDGNTAKLKKKEPKFYSITVSPSKYELNRLQNSREDLKIYTRELMRDYVTSFNREINGRPISIGDIKYYAKIEHQRTFKGTDFQIKENQTFATKILQLKTEIRNIQEGRAEGNIKKMKIEIAKLERQAPHQQNGKRIVQGMAKDGNQSHIHIVVSRKDASNSVSLSPGSKHKASEVEMHGKKVKRGFDRDKFFDKAEKTFDNTFGYKRNFAETYKARKDFIKNPKIYFASLLKLPTNEKALAFKIMGKSGIPMVPSIPVTQAKLAMKIFNRLRRGAEVAIKSSSIGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF21</accession>
    <name>A0A5C6ZF21_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Sodium:proton antiporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_15245</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015299">
        <property type="term" value="F:solute:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018422">
        <property type="entry name" value="Cation/H_exchanger_CPA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10110">
        <property type="entry name" value="PTHR10110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0915">Sodium</keyword>
    <keyword evidence="5" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="1 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="70"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="171"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="232"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="293"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="318"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="356"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="383"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="domain" description="Na_H_Exchanger" evidence="7">
        <location>
            <begin position="9"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD87828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="415" mass="45664" checksum="8FB16DC5787C1DBC" modified="2019-11-13" version="1">MEYYTIASILIVMSALFGYINERFLKLPITIGLMLITIVFTLIVIAIANFDDTLLLQEKELISNIDFETVLLDIMLSFLLFAGALHTNFNQLKIQRWPILAFATLGVSVSTFLVGISTYYLLMLFGFDINFIYCFLFGALISPTDPIAVLGILKKAKAPKKLEAKIVGESLFNDGVGVVVFLTIFAIAKLPGASIDVGSIARLFGQEVLGGVALGLVLGYVTYKLLKSIDSYEVEVIITIATVMGGSLLAHQWHLSAPLAMVTAGLIVGNDTVRKSSMSDTTETYVDKFWELIDVLLNTVLFVMIGMELLVLSLETNYILAGLIAVPLVLLSRYLSLWLPVKFFSKRLKFVPHTNLIMTWGGLRGGISIALALSLSTEMHRELFLVMTYVIVVFSIIGQGLTVEPIIKRLARGAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF37</accession>
    <name>A0A5C6ZF37_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thioredoxin domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11610</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02955">
        <property type="entry name" value="SSP411"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004879">
        <property type="entry name" value="DUF255"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024705">
        <property type="entry name" value="Ssp411"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42899">
        <property type="entry name" value="PTHR42899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03190">
        <property type="entry name" value="Thioredox_DsbH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006402">
        <property type="entry name" value="UCP006402_thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredox_DsbH" evidence="1">
        <location>
            <begin position="36"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="717" mass="82222" checksum="9EB22F6D0C69DAB0" modified="2019-11-13" version="1">MKSKSLITFCILVLGIGLSGCAQKKEKKEEKEAVYQNRLSNASSPYLQGHADNPVDWYEWGEVALEKAKKENKPIIISIGYASCHWCHVMEEETFMDSSVAKIMNQNFVSIKIDREERPDIDQIYMNAATLNGGHGGWPLNAFALPNGKPFFAATYFPTKAWKDLLNQIAKTYEKNPERLVEAANLLTEGVKQQDIIDSPLKKEVLFTEEDYVGLWKNWKSVIDRKKGGFRRAPKFPLPVGWEFLLQYSALTGNEDALEAVKTTLTNMARGGIYDQLGGGFSRYSVDEDWFAPHFEKMLYDNAQLVSLYSNAYKITNDEEYEAVIRETLEFIERELSAENGGFYSSLNADSEGEEGLFYVWEEHELEKHLTPKEAEVFAEFYGVQSKGNWEDNKNILFREHKASVFAQKNDYTASEFQIHLKSAEKKLMAVRNKRIRPSTDDKILTSWNSLMVIGYLDAYTALGKEAYKTKASEALSFIENNLMQNDGGLYRNYKDGKPSINAFLDDYAFLASAYIKMYEVTLNKKWLVKSKKLVDYTLKHFLNKDSGMFYYTSETDKKLIARKMEISDNVIPASNSEMAMVLYKLGNYFQENTFISHSQKMLAQVKERSLDGAAYYANWAKLMGMMVYTPFEIAVMGKDAVDLNLELQKNYVPISIFMGGKKEDMPLLHLKLVEDETYIYVCRDRTCKLPVKQVDQAMQQISDFLKEDKVSKHLRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF89</accession>
    <name>A0A5C6ZF89_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">SDR family NAD(P)-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_12125</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="129" mass="14249" checksum="0AA57F7EC9A0CEB1" modified="2019-11-13" version="1">MDFKNKIIWITGASSGIGKGLAKELSKNDCKLILSSRRQESLEAVKSECQQPESIAILPFDLGDYENLKPIAEKAIQLFGKIDILINNGGISQRSLVIDTNISVDKRLMEVNYLGTVGLSKALSCFRQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFD8</accession>
    <name>A0A5C6ZFD8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GTP 3',8-cyclase</fullName>
            <ecNumber evidence="4">4.1.99.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="primary">moaA</name>
        <name evidence="14" type="ORF">ESY86_13325</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>AH2 + GTP + S-adenosyl-L-methionine = (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate + 5'-deoxyadenosine + A + H(+) + L-methionine</text>
            <dbReference type="Rhea" id="RHEA:49576"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:131766"/>
            <dbReference type="EC" id="4.1.99.22"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.22" evidence="4"/>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_066434197.1">
        <property type="nucleotide sequence ID" value="NZ_VORO01000015.1"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019008">
        <property type="term" value="C:molybdopterin synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061798">
        <property type="term" value="F:GTP 3',8'-cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013483">
        <property type="entry name" value="MoaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000385">
        <property type="entry name" value="MoaA_NifB_PqqE_Fe-S-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010505">
        <property type="entry name" value="Mob_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06463">
        <property type="entry name" value="Mob_synth_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02666">
        <property type="entry name" value="moaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01305">
        <property type="entry name" value="MOAA_NIFB_PQQE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="12" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="13">
        <location>
            <begin position="11"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TXD88285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="330" mass="37670" checksum="88B5470600199EA7" modified="2019-11-13" version="1">MIEEKKKIVDNFGRAHTYLRISLTDRCNLRCFYCMPEEGIELMEKSNIMTIEEIIELATTFRDLGVDTIRLTGGEPLVRKNFGYLVEELAKLGVTLKITTNGIMLDKYLDLFQKIGLKKINLSLDTLDKAKSVFITKRDYFERIIKNIETALEMDMEVKLNIVLIKGVNDNEINDFIELTKNKNLTVKFIEFMPFKGNKWDWSKGVGKQEILDIVSERFGNIEVLQNPKHSTSSNFQVKGHTGSFAIVSTITNPFCADCNRIRLTADGKMMNCLFANSETDLLTPMRNGGEMNELIINAIKTKKFSRDGMDVKMDADHYEQNRSMISIGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFF9</accession>
    <name>A0A5C6ZFF9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Lacal_2735 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_16605</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000023">
        <property type="protein sequence ID" value="TXD87514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="66" mass="8042" checksum="413488A8257F48FA" modified="2019-11-13" version="1">MDPFEHIQKHQQKLMFRYKQLMEQAYNFRQTDSALSDISEFKAIKLLSKLQKLNYLNREPKKISPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFR0</accession>
    <name>A0A5C6ZFR0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_13000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="89" mass="10139" checksum="00E3093FE04DAD07" modified="2019-11-13" version="1">MANVRDLKKDINFVLGDIIEAVYVWEYNNTDKGTKESEAIISEAIATFDELIAKVNAKNVEDNKAHFKSIRQELETKGRELIEKINKLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFS3</accession>
    <name>A0A5C6ZFS3_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">tRNA-specific 2-thiouridylase MnmA</fullName>
            <ecNumber evidence="7">2.8.1.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 8" type="primary">mnmA</name>
        <name evidence="8" type="ORF">ESY86_12205</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>AH2 + ATP + S-sulfanyl-L-cysteinyl-[protein] + uridine(34) in tRNA = 2-thiouridine(34) in tRNA + A + AMP + diphosphate + H(+) + L-cysteinyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:47032"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11726"/>
            <dbReference type="Rhea" id="RHEA-COMP:11727"/>
            <dbReference type="Rhea" id="RHEA-COMP:11728"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61963"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:87170"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.8.1.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the MnmA/TRMU family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.13" evidence="7"/>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016783">
        <property type="term" value="F:sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01998">
        <property type="entry name" value="tRNA_Me_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00144">
        <property type="entry name" value="tRNA_thiouridyl_MnmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023382">
        <property type="entry name" value="Adenine_a_hdrlase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004506">
        <property type="entry name" value="tRNA-specific_2-thiouridylase"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00420">
        <property type="entry name" value="trmU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="2 7" id="KW-0820">tRNA-binding</keyword>
    <feature type="region of interest" description="Interaction with target base in tRNA" evidence="7">
        <location>
            <begin position="95"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with tRNA" evidence="7">
        <location>
            <begin position="150"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with tRNA" evidence="7">
        <location>
            <begin position="346"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="100"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine persulfide intermediate" evidence="7">
        <location>
            <position position="200"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="7"/>
            <end position="14"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Interaction with tRNA" evidence="7">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with tRNA" evidence="7">
        <location>
            <position position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD88501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="395" mass="44513" checksum="AF2499779862D855" modified="2019-11-13" version="1">MKRVIVGLSGGVDSSVAAYLLKQQGYEVIGLFMKNWHDDSVTISDDCPWLDDSNDAMLVADKLGIPFQTVDLSEQYKERIVDYMFEEYKNGRTPNPDVLCNREIKFDVFMKIALDLGADYVATGHYCRKGSLEKDGETVYQLLSGVDNNKDQSYFLCQLSQAQLTKALFPIGELTKPEVREIAKAQDLVTADKKDSQGLCFIGKVRLPEFLQQKLKPKEGLIVEIPKSLESFSVEMPEFESKIDELQFLAQKPHYQVSEGKVVGKHQGAHYFTKGQRKGLAVGGTVEPLFVIDTDVDENVIYTGQGHSHPGLLKRVLFVNNDELHWVRADLALKTNDSMEVMARIRYRQKLGKATLYKTRDGLFVEFENQQSAITEGQFVAWYLDDELVGSGVIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFZ8</accession>
    <name>A0A5C6ZFZ8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protoheme IX farnesyltransferase</fullName>
            <ecNumber evidence="8">2.5.1.141</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Heme B farnesyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Heme O synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">cyoE</name>
        <name evidence="8" type="synonym">ctaB</name>
        <name evidence="9" type="ORF">ESY86_14490</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>(2E,6E)-farnesyl diphosphate + H2O + heme b = diphosphate + Fe(II)-heme o</text>
            <dbReference type="Rhea" id="RHEA:28070"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
            <dbReference type="ChEBI" id="CHEBI:60530"/>
            <dbReference type="ChEBI" id="CHEBI:175763"/>
            <dbReference type="EC" id="2.5.1.141"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Porphyrin-containing compound metabolism; heme O biosynthesis; heme O from protoheme: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="8">Carbon 2 of the heme B porphyrin ring is defined according to the Fischer nomenclature.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the UbiA prenyltransferase family. Protoheme IX farnesyltransferase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.141" evidence="8"/>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00834">
        <property type="reaction ID" value="UER00712"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008495">
        <property type="term" value="F:protoheme IX farnesyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048034">
        <property type="term" value="P:heme O biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd13957">
        <property type="entry name" value="PT_UbiA_Cox10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00154">
        <property type="entry name" value="CyoE_CtaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006369">
        <property type="entry name" value="Protohaem_IX_farnesylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030470">
        <property type="entry name" value="UbiA_prenylTrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43448">
        <property type="entry name" value="PTHR43448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01473">
        <property type="entry name" value="cyoE_ctaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00943">
        <property type="entry name" value="UBIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0350">Heme biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8 9" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="37"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="110"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="165"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="205"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="232"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="264"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000689"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD88117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="288" mass="31895" checksum="F9BA51EAF0DC27EB" modified="2019-11-13" version="1">MSSLISDFKEITKIRLSVSVVFSAIAGYMLGAVEVDALSLVLLAFGGYFMVGASNAFNQIIEKDLDVLMDRTKNRPIPAGRMSVSTAFIIATFFTILGIATLYVINERTAMYGAISIFLYTCVYTPLKTKTPLAVFVGAIPGAIPFMLGWVAARGQFGIESGTLFALQFFWQFPHFWAIGWFLFEDYKKGGFYMLPTGKRDKGTAVQIIIYTIWTILVSIVPVFGVTGDLKLSIVSAIIVFALGVFMLYYALQLFKERSAKAAKQLMLASVGYITLVQIVYVIDKFIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG12</accession>
    <name>A0A5C6ZG12_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SGNH/GDSL hydrolase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_14050</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023124957" evidence="1">
        <location>
            <begin position="21"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="SGNH_hydro" evidence="2">
        <location>
            <begin position="39"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="235" mass="25512" checksum="A98BAB4168D494A1" modified="2019-11-13" version="1">MKKNLLIIFTVGLISSCSSSGVVVKAPIAPTDISIDLLALGDSYTVGESVCDSCSFPEQLKDSLLANITSDRPVNLRVIAKSGYTTTKLKNAIASAEIANSYDIATLMIGVNNQYQDKSLSIYKKEFSDLVQTAIRATKGDKDKVIVLSIPDYGFTPYGQNSGNAKTIFKELNVYNTIAENYCEAQGVTFLNITDITRQGIQNPDLVASDGLHPSKLAYARFVARMIPIVLQKLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZG51</accession>
    <name>A0A5C6ZG51_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_11635</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="72" mass="8380" checksum="AA0E30C0F2614544" modified="2019-11-13" version="1">MGNGFEAVPPFENLIQMEFNGFSYSKIKVVIPNDYFTLYEGSNIDKVYYDMEHGIVGLDYTQNNLEFRLITE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGA0</accession>
    <name>A0A5C6ZGA0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">BlaI/MecI/CopY family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_14140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BlaI transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005650">
        <property type="entry name" value="BlaI_family"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34134">
        <property type="entry name" value="PTHR34134"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03965">
        <property type="entry name" value="Penicillinase_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019455">
        <property type="entry name" value="CopR_AtkY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="120" mass="14029" checksum="A0F0EF3E17C91238" modified="2019-11-13" version="1">MKQLTKAEEEIMQVLWQLEKATVKEMMELLPKPKPAYNTVSTIVRILENKGFVDYEKQGKGHLYFPLMPKQEYSNQSLNTLVDNYFQGSFKSMVSFFVKKNDVDLKDVEAMLKEITKNKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGC1</accession>
    <name>A0A5C6ZGC1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GyrI-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_13180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010499">
        <property type="entry name" value="AraC_E-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029442">
        <property type="entry name" value="GyrI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011256">
        <property type="entry name" value="Reg_factor_effector_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06445">
        <property type="entry name" value="GyrI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00871">
        <property type="entry name" value="AraC_E_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55136">
        <property type="entry name" value="SSF55136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AraC_E_bind" evidence="1">
        <location>
            <begin position="82"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="243" mass="27725" checksum="76EB1139712B846C" modified="2019-11-13" version="1">MHQVETGELVQNLNFDGIDYDFHWALSRIDDSTTQVNIGIKDRENSLKNKVNILVNDTDFEKKVKPTISDFIMVLNTHLENFEVKIEGESTSPSTYCAYIPVTTKQFLKAKGMMENYGILSTFLIANGVVLNGKPIVEVRSWDTETDSISYNFCYPIVKKEGLPSHPTLRYKEIKGGKAIKAIYNGNYITSDRAWYALIDYAKKKNIQLKHTPIEVFNNNPNMGGNELTWKAEIYMPIKNKTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGD7</accession>
    <name>A0A5C6ZGD7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Xanthine dehydrogenase family protein subunit M</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_13265</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000015">
        <property type="protein sequence ID" value="TXD88273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005107">
        <property type="entry name" value="CO_DH_flav_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036683">
        <property type="entry name" value="CO_DH_flav_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002346">
        <property type="entry name" value="Mopterin_DH_FAD-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03450">
        <property type="entry name" value="CO_deh_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00941">
        <property type="entry name" value="FAD_binding_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01092">
        <property type="entry name" value="CO_deh_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55447">
        <property type="entry name" value="SSF55447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="328" mass="35606" checksum="88298D7AA029D6BB" modified="2019-11-13" version="1">MRPFKYTGAQNKDQALQAFTATSHYLGGGTNLVDLMKEDVERPDQLIDINNLDYKKITSNENGGLTLGGMLSNSETANHPEVRTNYPLLSMAMLSAATAQIRNMASNGGNLLQRTRCPYFFEVSMPCNKREPGSGCGALNGMNALHAIFGYSDSCIATNPSDMCVALAAIGATVEVQQTDGSSRMIAFTDLHRLPGDRPEKDTTLMQGELITAIHLSEPEFADHYYYLKIRERSSYAFALVSVAAGLQVKSGVITKVGLAMGGVAHIPWKLTKAEAFLAGKKPTSENFEAAAALEMKDAKPFEANTYKVEMGKNAIVRALTQAYERTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGL0</accession>
    <name>A0A5C6ZGL0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">GTP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_12670</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018652">
        <property type="entry name" value="DUF2082_NA-bd_Znr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09855">
        <property type="entry name" value="zinc_ribbon_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="69" mass="7899" checksum="E283DD6EAF496548" modified="2019-11-13" version="1">MQHRNYKCPKCNNTTFKTGQMRATGGTLSKIFDVQNKKFSSVTCTQCTYTEFYKTKTSGLSNVFDFFTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGS8</accession>
    <name>A0A5C6ZGS8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 8">Translation initiation factor IF-2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 11" type="primary">infB</name>
        <name evidence="11" type="ORF">ESY86_14340</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03702">
        <property type="entry name" value="IF2_mtIF2_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00100_B">
        <property type="entry name" value="IF_2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044145">
        <property type="entry name" value="IF2_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006847">
        <property type="entry name" value="IF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000178">
        <property type="entry name" value="TF_IF2_bacterial-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015760">
        <property type="entry name" value="TIF_IF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023115">
        <property type="entry name" value="TIF_IF2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036925">
        <property type="entry name" value="TIF_IF2_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43381">
        <property type="entry name" value="PTHR43381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11987">
        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04760">
        <property type="entry name" value="IF2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52156">
        <property type="entry name" value="SSF52156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00487">
        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01176">
        <property type="entry name" value="IF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 7 8" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="10">
        <location>
            <begin position="449"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="56"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="56"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="116"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="254"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="309"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="345"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="458"/>
            <end position="465"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="505"/>
            <end position="509"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="559"/>
            <end position="562"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD88063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="951" mass="104452" checksum="74A088FFB89BAD0F" modified="2019-11-13" version="1">MAQTRLNKVLRELNISIDRAVDFLESKGVEIEKKPNTKISEEVYAVLSNEFQTDANKRAESQEVSEAKLKEKEELRVQREREIEEKAEREAKQKEVVRAKAELSGPKQVGKINLDGDTLKVKKEEIAPPKETEKEPAKEPAKEPAKKVAEETAEAPVKEAEIAPEKPKEKPKEEKQVSEAPVAEDKKESAKEEVSDTEKAPEKAIAEKPDTEKVTPKFEVKKEPEAGSTESASDDTLITNYKKLSGPKIAGEKIDLSQFKKPKKKKDDKKVGDADKKKRRRISKGPAGTDSRPAKAAPRGGYKGRNPIKRSTGVKEDPSEADVQKQVRETLEKLQGKSSKGKGAKYRREKRDQHREQTEKDIADAAESKILKVTEFVTASEVATMMDVSVTEIISACMSLGMMVTMNQRLDAETLSVVADEFGYEVDFVTSDLEDSVKVILDNPEDLKPRAPIVTVMGHVDHGKTSLLDYIRKENVIAGESGGITQHIGAYGVTLDNGQKMAFLDTPGHEAFTAMRARGAQVTDLAIIVIAADDSIMPQTKEAIAHAQAASVPIIFAINKIDKPGANPEKVKEGLAQMNLLVEDWGGKIQSHDISAKNGTGIKELLEKVVLEAEILELKANPDKMASGTVVEAYLDKGRGYVSTILVQAGTLKVGDYVLAGKNSGKVRAMQDERGKEVKTAGPSTPVSILGLDGAPQAGDKFNVFADEREAKQIAAKRMQLQREQTVRTQRHITLDEIGRRIALGDFQELNIILKGDVDGSVEALTDSFQKLSTEEIQVNIIHKGVGAITESDVLLATASDAIIIGFNVRPMGNARQIADKEAIDIRMYSIIYDAINDLKDAMEGMLSPEVKEEITGTAEIRETFKISKVGTIAGCMVLSGKIYRNSGIRLIRDGVVIHTGLLTSLKRFKDDAKEVAKGYDCGIQLKNYNDIEIDDTIEAFQEVEVKKKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGV4</accession>
    <name>A0A5C6ZGV4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_14505</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005171">
        <property type="entry name" value="Cyt_c_oxidase_su4_prok"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03626">
        <property type="entry name" value="COX4_pro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="90"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD88093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="126" mass="14669" checksum="6355CB2FD211A337" modified="2019-11-13" version="1">MAHAHKLAIFQGRLKFKSNTQKIWGVLILLTIITAIEVVLGIYKPDVLEGSFIGMKVLNWIFIVLTLVKAYYITWDFMHMRDETSALRRMVVWTALFLVCYLVFILLQEGGYVESVFKRGYLKTDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH66</accession>
    <name>A0A5C6ZH66_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd12105">
        <property type="entry name" value="HmuY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025921">
        <property type="entry name" value="HmuY"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14064">
        <property type="entry name" value="HmuY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022926944" evidence="1">
        <location>
            <begin position="27"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="211" mass="22714" checksum="1F70C0C3070544EF" modified="2019-11-13" version="1">MTTMKTLQTLTLAVLFIGFTSCTSDDDNTPTPDPVQAELVSNLFAPQTGGQGTGQDEGGPFTKFDFKTGAETTSDTEWDIAFRGTTIAVNGGTTTGTNDEPTRNGDAGASIVTGTFDSINTADGLTFAQDTASGFAIPTGSDNGWYNYDFMNNIIMPIPGKMLVFRTRDGNYAKVEILSYYKDQDNSTPANGRHYTFNYVYNPNAGETSFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH93</accession>
    <name>A0A5C6ZH93_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="4">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_09870</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="4"/>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3 4" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="6">
        <location>
            <begin position="20"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="2-oxoacid_dh" evidence="5">
        <location>
            <begin position="210"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD89073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="438" mass="49200" checksum="17BD09AB828F2D9F" modified="2019-11-13" version="1">MNKLIETIKTQVDSVNDDSVIVTQILVTDGQQVFEDDVLAEIETSKAQLEIISSSEGYIKILCLVDQEVMIGETLFEIFAEEIPEDELNIMKVSVKNAESDSVESNSERQVEILEFETQFSKKAKARIERENINVADFKSMQFVTINDIENFLNPNTKRQNNNRQFEIVQVSKQKSDNRSKTVVLGKQKLNEMNYLSSVNSSGLVSRLSIPIEASLKAIVKSQNFISSTPLPVIVYEVSRLLTKYPNLNSYFESNSKIEHQSINVGVALDNGTNGLKVGSILKCDDKNLHDIEENITDLSLKYNNNNLSLEEISAATFTITDLFATGVSNFHPLVNYNNAAILGICGLVNNAFNIELAFDHRISNGLEVSKFLNDLKMRLETRFNQGQYDKNLTALEDIECYKCLRTAADDLNGKIYFIKVANSKEEGQICSNCFNGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHF9</accession>
    <name>A0A5C6ZHF9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyl-CoA carboxylase subunit beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_12065</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034733">
        <property type="entry name" value="AcCoA_carboxyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011763">
        <property type="entry name" value="COA_CT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011762">
        <property type="entry name" value="COA_CT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045190">
        <property type="entry name" value="MCCB/AccD1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22855">
        <property type="entry name" value="PTHR22855"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01039">
        <property type="entry name" value="Carboxyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50989">
        <property type="entry name" value="COA_CT_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50980">
        <property type="entry name" value="COA_CT_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CoA carboxyltransferase N-terminal" evidence="1">
        <location>
            <begin position="12"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="domain" description="CoA carboxyltransferase C-terminal" evidence="2">
        <location>
            <begin position="270"/>
            <end position="533"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="542" mass="59611" checksum="D6102A4793565ADC" modified="2019-11-13" version="1">MDLNFNKNEDHNKLLLSDLRKRLAQVKLGGGQKRIDKHHEKGKMTARERVDFLLDSKKPSIEIAAFAGEDMYEEHGGCPSGGVVVKMGYVKGKQCIVVANDATVKAGAWFPITGKKNLRAQEIAIENRLPIIYLVDSAGVYLPLQDEIFPDKEHFGRIFRNNAVMSSMGITQIAAVMGSCVAGGAYLPIMSDEALIVEKTGSIFLAGSYLVKAAIGESIDNETLGGATTHCEISGVTDYKAKDDKDALETIQRLMDKIGDYDKAGFNRVDAKKPKENVDDIFGIVPRSRADQYDMKEIIKRLVDKSEFDEYKEGYGKTIITAYARIDGWSVGIVANQRKLVKTKGGEMQFGGVIYNDSADKATRFIANCNQKKIPLVFLQDVTGFMVGSKSEHGGIIKDGAKMVNAVSNSVVPKFTIIIGNSYGAGNYAMCGKAYDPRLIVAWPSAELAVMSGNSAAKVLLQIETASLKKKGEKITEEKEKELFDKIKNRYDKQVSPYYAAARIWTDAVIDPLDTRTWISMGIEAANHAPIEKKFNMGVLQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHI1</accession>
    <name>A0A5C6ZHI1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD(P)/FAD-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_09065</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="1">
        <location>
            <begin position="3"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="434" mass="49591" checksum="DABF5933F4ABA7F5" modified="2019-11-13" version="1">MEHIVIIGNGISGVTTARHIRKLSDHKITIISAETEHFFSRTALMYIYMGHMTYTHTKPYEDWFWKKNRIELKKAYVEHIDTDAKSLKFADGDTMTYDKLVVATGSKVNKFGWPGQDLKGVQGLYSKQDVDQLEADAPNNKVCKRAVIVGGGLIGIELAEMLNSRNIPVTFLVRESSFWNGVLAEGESEMLNRHIKNHHIDLRLSTNLKAIKADENGRVKSVIIEETGEELACDLVGLTAGVSPNIEMIKNTGIKTDKGVIVNKYLETNIKDVYALGDCAEQQDPAHNRPPIEAVWYTGRMMGEVLAQTLCGNKMAYNPGHWFNSAKFLDIEYQTYGWVFGKKRRPDYEQHFHWKHDDDTKCITIAYHKESRQFLGINTFGIRMKQVVFDQWLTEKQDVDHVVSHLKKANFDPEFYAHYEKDIQSAFEAVLQRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHN7</accession>
    <name>A0A5C6ZHN7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF4834 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_11880</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032272">
        <property type="entry name" value="DUF4834"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16118">
        <property type="entry name" value="DUF4834"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="14"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="49"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="94" mass="11059" checksum="62C5DD220E4EEFAA" modified="2019-11-13" version="1">MLQAASLIGFLRTILVIVLIYYGIKILIRFFAPYFVRYMSKKMQERFGGQFQQQQRQQQAQNERAGETVIDKVPNSDKNSDKEVGEYIDYEEID</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHP7</accession>
    <name>A0A5C6ZHP7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022927537" evidence="1">
        <location>
            <begin position="24"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="186" mass="21345" checksum="551EE9A508FFFA37" modified="2019-11-13" version="1">MKKYMYLSLFVSLLFSCNSNGQATDSLSKNNRSIPASNFVFSGDYNDLLTLQMASQITGFDASNAIKTHAMKGMMTETLRYYWENDRKVEIEGSTLPRVDRVQINWIDDEADMDSFLYFIDPEKHPELIKVNGVGESAYWNSNKKYLEVYYNGISFRLEVDISNDDTLDKEKTIALAKQIIDAKLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI52</accession>
    <name>A0A5C6ZI52_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Crp/Fnr family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_11325</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012318">
        <property type="entry name" value="HTH_CRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13545">
        <property type="entry name" value="HTH_Crp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00419">
        <property type="entry name" value="HTH_CRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51063">
        <property type="entry name" value="HTH_CRP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="2">
        <location>
            <begin position="1"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="HTH crp-type" evidence="3">
        <location>
            <begin position="131"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD88861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="208" mass="23372" checksum="D36FC4D2AAF9B2FA" modified="2019-11-13" version="1">MTKEELKLVSDCKTTRFFKKGDVIFEEGEALNGVFCVRDGVAKLTKLNANGKDQTVKLLGRGDMIGQRSVISNERTNLSAVALNDIELCYVPRDQIVNPLQKNQEFSFDVLQNFAKDLKNSEDDLVNMAQKSVKQRIAETLLYVHRTFGVDANGYLSVVLSREDYASIVGTATESTIRILSQFKKDGFISTEGKLIKIENLEKLRQVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI99</accession>
    <name>A0A5C6ZI99_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glycoside hydrolase family 97 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_12845</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029483">
        <property type="entry name" value="GH97_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019563">
        <property type="entry name" value="GH97_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029486">
        <property type="entry name" value="GH97_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14509">
        <property type="entry name" value="GH97_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14508">
        <property type="entry name" value="GH97_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10566">
        <property type="entry name" value="Glyco_hydro_97"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022994143" evidence="2">
        <location>
            <begin position="22"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="domain" description="GH97_N" evidence="4">
        <location>
            <begin position="25"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_97" evidence="3">
        <location>
            <begin position="296"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="domain" description="GH97_C" evidence="5">
        <location>
            <begin position="601"/>
            <end position="701"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF10566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF14509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD88401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="705" mass="80441" checksum="687CF89CA8894220" modified="2019-11-13" version="1">MTKQILSILTLSLFISIQAIAQQIVSPDKSIQLNFSLNAEGVPTYQMSFKDKEVIKTSRLGFQIKEDEQDLKNGFTVVNSENSTFDETWKPVWGEESEIRNHYNELLVSLKQEPSQRIMNIRFRVFNDGVGFRYEFPEQANLGHFVIEKELTQFAMTNDHTAFWIPGDYDTQEYDYIESRLSEIRDLMTNSITSNLSQTSFSPTGIQTSLLLKTDDGLYINLHEAALIDYSTMHLELDDKDFVFNAWLTPDVQGSGPYMMAPATTPWRTIIVSDDATDILASRMTYNLNEPSKIEDTSWIKPMKYVGVWWEMITGKSSWAYTDDLKAVKLGVTDYTKTKPNGKHGANTKHVKELIDFASEHGFDGVLVEGWNEGWEDWFGHSKDYVFDYVTPYPDFDLEGIETYAKNKGVEMIMHHETSSSVRNYERHLDQAYQFMKDHGYNAVKSGYVGDILPRGENHYSQWMVNHYQYAVEKAAEYKIMVNAHEAVRPTGIARTYPNLIANESARGTEYQAFSGSKPNHVTVLPFTRLIGGPMDYTPGIFEMDLSKLNPDNKSHVNSTIANQLALYVTMYSPLQMAADLPENYNRFLDAFQFIKDVGLDWEKSVYLEAEPGSYITIARKEKGTNDWFIGNVNGKKDRVSEISLDFLDKGKKYLATIYSDGEDANYRTNPQSYTIKKMNVTSKSKLSLKSVEGGGYAISIIEVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIF3</accession>
    <name>A0A5C6ZIF3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_09540</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="11"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="109" mass="12338" checksum="C0050F35FD9A933B" modified="2019-11-13" version="1">MTFGERLGLVRKRQKLSQANIGKLIGINGDAYGRYERNEVKPTIEMATKIANALKVSLDYLVGSTDLVLDTELLKRIEQVSKLTPKEKEHIYITIDALIRDFNAKKVYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIG9</accession>
    <name>A0A5C6ZIG9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_07555</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89633.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="9"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="311"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="43"/>
            <end position="50"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="348"/>
            <end position="355"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD89633.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="563" mass="62620" checksum="9476DF268FB3F7B4" modified="2019-11-13" version="1">MPESKLLTVKDLSISFYSEGKAIEIIHNIAFDLQPNEILGIVGESGSGKSVSSLAILGLLPKRISKITNGSILFEGKDLTRLETKAFQKIRGNDIAMIFQEPMSSLNPSMTCGKQVLEILRQHTKLSKTEAKTEVLSLFEKVKLPMPERVYKAYPHEISGGQKQRVMIAMAIACKPKILIADEPTTALDVTVQKEIILLLKQLQAEEGMSIIFISHDLSLVSEIADRILVMYQGEIVEQGDVRTVFKSPQHLYTKALVNSKPSMETRLLQLPTITDFINDSANKTIISSEERQIQHQKLYAQSPLLEVVNLEKEYISKSGWFSKPEHFKAVDGVSFKLYKGETLGLVGESGCGKSTLANAILQLDKATAGQILYKGVDITKLSNTEVRALRKDIQIIFQDPYASLNPRLSVGQAILEPMQVHNIGSSDKERKQKVLDLLEKVGLEASVYNRYPHEFSGGQRQRIGIARAIALEPELIVCDESVSALDISVQAQVLNLLNDLKANFGFTYIFISHDLAVVKYMSDQLIVMNQGHIEEMDDADVIYAAPKKEYTKKLIHAIPKGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZII0</accession>
    <name>A0A5C6ZII0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_10845</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="90" mass="10509" checksum="0AA311AF1478CDF4" modified="2019-11-13" version="1">MDANLSLFNQINSLCYWLLTESNYKSSVILDADKDSYFVRVKKGNQSLYAYQIPQFSKKNPRFLNFELTAVVNSLLLIKDTVMQRRYESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIL3</accession>
    <name>A0A5C6ZIL3_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Phosphoribosylglycinamide formyltransferase</fullName>
            <ecNumber evidence="3">2.1.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">5'-phosphoribosylglycinamide transformylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">GAR transformylase</fullName>
            <shortName evidence="3">GART</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">purN</name>
        <name evidence="5" type="ORF">ESY86_08140</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the transfer of a formyl group from 10-formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>(6S)-10-formyltetrahydrofolate + N(1)-(5-phospho-beta-D-ribosyl)glycinamide = (6S)-5,6,7,8-tetrahydrofolate + H(+) + N(2)-formyl-N(1)-(5-phospho-beta-D-ribosyl)glycinamide</text>
            <dbReference type="Rhea" id="RHEA:15053"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:143788"/>
            <dbReference type="ChEBI" id="CHEBI:147286"/>
            <dbReference type="EC" id="2.1.2.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 3">Purine metabolism; IMP biosynthesis via de novo pathway; N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide from N(1)-(5-phospho-D-ribosyl)glycinamide (10-formyl THF route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the GART family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.2" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00126"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004644">
        <property type="term" value="F:phosphoribosylglycinamide formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd08645">
        <property type="entry name" value="FMT_core_GART"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01930">
        <property type="entry name" value="PurN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002376">
        <property type="entry name" value="Formyl_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036477">
        <property type="entry name" value="Formyl_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004607">
        <property type="entry name" value="GART"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001555">
        <property type="entry name" value="GART_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00551">
        <property type="entry name" value="Formyl_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53328">
        <property type="entry name" value="SSF53328"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00373">
        <property type="entry name" value="GART"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Formyl_trans_N" evidence="4">
        <location>
            <begin position="2"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="5'-phosphoribosylglycinamide binding" evidence="3">
        <location>
            <begin position="12"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>(6S)-10-formyltetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>(6S)-10-formyltetrahydrofolate</name>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
        </ligand>
    </feature>
    <feature type="site" description="Raises pKa of active site His" evidence="3">
        <location>
            <position position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD89352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="204" mass="22722" checksum="E8C922D1CF212011" modified="2019-11-13" version="1">MKRIIILASGSGSNAENLIHFFRDHKTISVVQVLSNNSQAKVLERTKKLGVSAFSFNRIAFAKTDDVLKLLKASQPDLIVLAGFLWKLPEHIIEAFPDKIINIHPALLPKYGGKGMYGSFVHEAIVANKETETGISIHYVNANYDEGAIIFQTKCPVNATDTAEDIAAKIHDLEMEHFPKVVQEILNSKKNKIPKPKTYNQKLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIP4</accession>
    <name>A0A5C6ZIP4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_04625</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="200" mass="23534" checksum="BDAC6F70020BEA76" modified="2019-11-13" version="1">MFQITDKNSEIRVNQFHPRHQRSIFGTPMTQILQMPTDKNSGIRANQFNPRHQRSIFGTQITQILQMFTDKNSGIRANQYNPRHQRSMFGTQMTQILQMSTDKNSEIRANQYNPRHQRSIFGTQITQILQMFTDKNSGIRANQFHPRHQRSIFGTQMTQIWQMITDKNSGIRANQYNPRHQRSIVGTQMTQILQMPTDKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIS4</accession>
    <name>A0A5C6ZIS4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">GxxExxY protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_07945</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026350">
        <property type="entry name" value="GxxExxY"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13366">
        <property type="entry name" value="PDDEXK_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04256">
        <property type="entry name" value="GxxExxY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="130" mass="15226" checksum="864E8927449CE2E2" modified="2019-11-13" version="1">MEKSNILYKEESYKIIGACMKVHRELGSGFLEAVYEEALNKEFIKQDIPFKSQVKLRVFYDGEQLDKYYKADFICYDKIILEIKSVRQVPIAFYAQTKNYLAATKKELGMLVNFGQPSLFYKRIVNSEKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIV1</accession>
    <name>A0A5C6ZIV1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="10">TonB-dependent receptor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ESY86_09175</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell outer membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TonB-dependent receptor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009279">
        <property type="term" value="C:cell outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071702">
        <property type="term" value="P:organic substance transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039426">
        <property type="entry name" value="BtuB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012910">
        <property type="entry name" value="Plug_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037066">
        <property type="entry name" value="Plug_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000531">
        <property type="entry name" value="TonB-dep_rcpt_b-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036942">
        <property type="entry name" value="TonB_rcpt_b-brl_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010917">
        <property type="entry name" value="TonB_rcpt_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30069">
        <property type="entry name" value="PTHR30069"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07715">
        <property type="entry name" value="Plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00593">
        <property type="entry name" value="TonB_dep_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01156">
        <property type="entry name" value="TONB_DEPENDENT_REC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0998">Cell outer membrane</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0675">Receptor</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0732">Signal</keyword>
    <keyword evidence="2 5" id="KW-0798">TonB box</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022859254" evidence="7">
        <location>
            <begin position="19"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="domain" description="Plug" evidence="9">
        <location>
            <begin position="138"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="domain" description="TonB_dep_Rec" evidence="8">
        <location>
            <begin position="344"/>
            <end position="995"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="895"/>
            <end position="916"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023237"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF07715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD89216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="997" mass="110232" checksum="21CDC7E33E44D018" modified="2019-11-13" version="1">MKYLYTLTMLCMVSMSFAQQDFTISVIDAETNAPVPNIDIKLTNQARGISLTQQTNAQGKTIFRSIPTLNGYQVFFEGNSDFGPNFSEKIDVRSNQNPNVQLQLNKSIGNSQDLEEVLITNVSSAKINRRDAEVAFELTAEEIQEIPVEGRDITRVLYRLPNVTQATGFFPEAANVSVNGGNSLFTSYLIDGMDNNENFLGGQRFAIPSGFVKDITVFSSNYSAEQGLTSNGIIDVTTKSGTNETTGEVFFVTRPGPSIDGTSQFAQRDLSGNQVKDGFARYQAGVGIGGALVQDKTFYYFNFEHTTDVKDNLLNVPQLGVSETVQGTNYFEYFSAKIDQIWSSNFRSSLRANVGFVGIERQGGGLDGGVQFQTAGNNQERNSINIALKNSYNLGVLSAETNLQYSRFRWNYAAANNPDNPQVVVLSPADETLAILGHPGYIFDALENTVQFQQKFKYYVKNHTIKAGLNFISSDHTLFGGGNPNGNYTVRLNQNQLDNLRTSGLSANFGINDIPNDVEVTNYNVELRPKSFGKTHNNTSIYVEDLWSATERLNLTLGLRYDYDNLSKGGSDDGDTNNIAPRFNFNYELNNKSVIRGGYGLAYEKINYAIYSDALQQNTTSADYKAQIQAFIDQGILPADTNIDAVTFAGNISANLGSVPYLQGPSAESLQDQREGAFSNERRILNPNGYDNPYSHQFSIGYQLQVEDDKLFFVDMYHNRGENLQRLRNLNAAAQFPIGDDFSPDDVRTPAEADATRPIPIVNGAGIINGQAVSGVARNVVVSETEGKSRYFAASFNYQKTRGTDDYAYRLNYTLSSLKNDTEDINFRPQDGNNYGSEYGPSINDRRHNINGIFNYYPFQGTTVTIASLLQSGQPINRIPDVAIFGTTDLNGDGSAFGDAYQGNSDRSPGEDRNSDRLPWSFNFDLGIQHQFTLTEGTRLEIRADVFNVFNVENLSGYSNNATQSNQIQPGPASSGVFIQRNAGPPRQFQFGARYLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIZ1</accession>
    <name>A0A5C6ZIZ1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_08065</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="27"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="153"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="661"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="950"/>
            <end position="1005"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1089"/>
            <end position="1109"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1009"/>
            <end position="1036"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="661"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="950"/>
            <end position="993"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1147" mass="132966" checksum="FE7B34242D7DE211" modified="2019-11-13" version="1">MAQNFLNIQQKLEQFVKRFYINELLKGVILFFAIGLLYFMATLLIEYVLWLNPTARTILFWLFIAVELTLFIKFIVLPLAKLFKLQKGINFEKASHIIGSHFPEVSDKLLNVLQLRQNKAQSELLLASIEQKSAELNPIPFNFAINFNKNAKYLKYAAIPVLILLFAYFTGKINWFSDSYQRVVNYKTAYEPPAPFQFFVINENLKAIENKDFKLLVSTAGDIIPENAQIHYNNQTYFLQQTAPGKFEYVFTQPKETISFNLSANEVGSKTYDLELINTPTLVNFEMVLEYPSYTKMTNNTLKSTGNATVPEGTNVTWRVSTKSTDEVNLYAKDTLIFTATSKGNFEAAKTIYSNTDYNISTSNANLINYENLAFSLSVIKDKYPEMTVKMEKDSLDNQSLYFYGQVSDDYALSKLQMVYYPSNSPEQKLYKGMKLSKSNFDEFVSAFPNQLELTEGVDYELYFQVFDNDAIHNFKSSKSPVFSYRKLTKDEEEQKQLKQQDETIKDISKTFEQLQKQDKELKELSKTQKEKKELNFNDKKKFENFIQRQKEQEELMKNFNKKLKDNLQEFQKENEEKDPFKEELQKRLDENEAQLKQDEKLLEELKKLQEKMNKEELTEKLEQLAKQNKNKERSLKQLLELTKRYYVQKKAEKLMEELEQLAEEQEQLSEAEKEKNTKEAQEELNKKFEDFQKELDALQKENKELKKPMELPQDKPTEESIKQDQEDAKEALEEQQKQDEQEQQKPEEQAPSDSGPQQKAKKKQKQAAQKMKEMSKKMASMMAMGGGDQLQEDATVLRQILDNLVLFSFDQEALMVQFKTMNINHNEYGKYLRKQNDLREHFEHIDDSLFSLSLRQPKISEEVNKQITEVFYNIDKSLGQLSENQIYQGVSAQQYTITATNELASFLSDILDNMNAQMNPSMGKGKGQGEQLPDIIMSQEALNKMMEDGMKKGGEKGKKPSEGKSGKGEGDGEKEGENGKPKDGKGGKDGNSESGQDAKGNGQSEQMNGELYEIYQKQQQLRQQLEEQLKNINSQNGSKNLGKKLLKDMEQIELDLINKGFTNQTLQKMMNLQHQLLKLENASFMQGEDEKRKADTNRQEFDNTTTNQIPTAKEYFNTTEILNRQALPLQQIYKKKVQAYFKKSDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ10</accession>
    <name>A0A5C6ZJ10_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">FtsX-like permease family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_10695</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD89012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038766">
        <property type="entry name" value="Membrane_comp_ABC_pdt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30287">
        <property type="entry name" value="PTHR30287"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="247"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="292"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="341"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="386"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="412"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="462"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="703"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="758"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="789"/>
            <end position="812"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="14"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="277"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD89012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="831" mass="90773" checksum="796E8E2B7914378F" modified="2019-11-13" version="1">MAWRDAKASRVRLLLFMASIILGIAAVVSIQLFSSNLKDNIKLQSKALMGADYIIDSRQLPTARAQAIIDSLQPDASEVNFVSMVAFPKNGGTKLVKVRALKGDFPFYGSIDTEPASAAANYQDSGGALVDATLLLQFNIKPGDSIKVGELTLSIAGALKAIPGSTAISTSVAPPVIIPNRFVDGTELLQFGSRKEYQYFYKASDSLNLSKFEQNIGPQLEAENSDLDTHTSTSAQLGSRYDNVGKFLNLAAFIALLLGCIGIASSVHIYIKEKLRAVAVLKCMGASRKQSFLIFLIQIAGIGLAGGLIGSLIGVALQTVFPYILEEFLPFAVEITISAQPILMGVFLGLFMSVLFALLPLLRTWYVSPLDVLRVDEQASQGPKKARIIVFAAILIFLFLFSFWLLKNAVYALGFVVATLITFAILAGISIGFMTLIKTYFPKRWGFTTRQSLLNLFRPNNQTVVLVVAIGLGTFLISTLYFTKDILLAKTEVEQSAENANMIILDVQTDQRAAVEQGLNARNLPVLDNIPLVTMRMHKIKAQLVNNIRQDSTSEIRGWILNHEFRTTYRDTLIDSEAIIAGEWVSELKTGKPVVISISDNLAEDAKVGVGDAIVFNVQGVLMETTIGSIRKVDWGQLQLNFSIVFPKGVLEQAPQFNVITTSVPDEAASAEIQRDLVAQFPNVSVLDLRQVYTILEDILDKIAWIINFMAFFSILTGIIVLIGSVRTSKYQRIKESVLLRTLGAKNTQILKISALEYVFLGLLGSLVGILLALLSSLGLALLVFKEPFVPSLIPFLVFLPGITLLVLAIGLSNIQTVLRSSPLEVLRREG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJA2</accession>
    <name>A0A5C6ZJA2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">DoxX family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_10185</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032808">
        <property type="entry name" value="DoxX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07681">
        <property type="entry name" value="DoxX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="41"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="72"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD89127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="123" mass="12943" checksum="988EE2FDC56E25C8" modified="2019-11-13" version="1">MNKNFNDLALLILRVGFGGLMLTHGIPKVSMLTDASGFPDPLGIGGTGSLILALIGEVLAPILIIIGLKTKWAAIPSIITMAVAAFMVHAADPLAKKEMALLYLIAFIVIFLAGPGKFSVDRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJB3</accession>
    <name>A0A5C6ZJB3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MerR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06510</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1240.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036724">
        <property type="entry name" value="Cobalamin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036594">
        <property type="entry name" value="Meth_synthase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52242">
        <property type="entry name" value="SSF52242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="1">
        <location>
            <begin position="7"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="299" mass="35063" checksum="1739CACCC77EA803" modified="2019-11-13" version="1">MNNIKSSFSIKDLENLTGIKAHTIRIWEKRYKLIEPDRTDTNIRLYSLENLQLLLNISYLKANGYKISKIAELEINAIPELVKEIAKKDSTHNHAMSTFKLAMLNFDQKLFYETYASLEKEKGFLQLFHEDLVPFMGEIGLLWQTDTITPAHEHFLMNLIRQKLLVSTEELQSRNQIDHKQIFVLFLPDNEVHELGLMLVNYEVISKGYQAIYLGQSVPIDSLKDLLNYYDEITFISYFTVKPEKAHINDYIKEFEQKLLMSKKINLWLLGRMVKEIDLSKLNKQIVSFKSIEELVKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJF1</accession>
    <name>A0A5C6ZJF1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06875</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="146" mass="16997" checksum="9C19D56A7CCFB44B" modified="2019-11-13" version="1">MTLITFLVAWFIATVGMTLFSAVWSRMSKNQFREPALLSLIIASNSNNDSIAVNAYKIGWLSHILLGAVFLGVYEILWLFTGLERNFLWAFLFGSGLGVLGIVGWMFMFKTIRDEFEFNYLHYYVHLYFAHLVFSFLALLSYFWFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJI0</accession>
    <name>A0A5C6ZJI0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF4837 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_08025</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032286">
        <property type="entry name" value="DUF4837"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16125">
        <property type="entry name" value="DUF4837"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="323" mass="36552" checksum="083B2E6C18B5F6B8" modified="2019-11-13" version="1">MKSTFLILISLIFCFSCQDEDAKRIVSSSSGNINSIVVVADNLLWENNVGETIRRVLAAPVEGLSVEEPLFAMKQMPPEVFEGFARKNRTVLKIEKGKEANTQIAQDSYARPQIVVVISGKTNEEIIEQIEMNAAKIIDAFNKQEITEKQRRISKSLFNDKDLEKDLGVSMNFPTAYRMAKAEDNFFWLRRDIKTGTIDMMVYEVPLSAIRSGDSTVVDIVRVRDSVGKKYIEGPLEGSYLATEDAFTPFISKTILDNKPAYETKGLWDVKNAFMSGPFINYAIEDKINNRYVIIEGYVFAPSVEKRDYMFELESILKSASIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJK0</accession>
    <name>A0A5C6ZJK0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Helix-turn-helix domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_03680</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain fatty acyl-CoA assimilation regulator (ScfR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010359">
        <property type="entry name" value="IrrE_HExxH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06114">
        <property type="entry name" value="Peptidase_M78"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="2">
        <location>
            <begin position="14"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="491" mass="57049" checksum="4852719E17D44C99" modified="2019-11-13" version="1">MEEDYIKLIFGLKLKQIRTDRNLSLFGLSKLSGLSKSYLNEIENGKKYPKPDKIAILSEKLDVPYDQMVSLKLDKNLAPIGDLLQSKVLKEIPLELFGIKERNLIDIVANAPAKVNAFISTIIEIAQNYNFSRESFYLASVRSFQEANNNYFEDLEQSVLKFAKAYQIDLNQIIASKDLEEILIEEYGYVIEKEELVKYKALGSLRSVFVPKSKTLLLTNEVDEAQRTFIYAKELAYNFLEIKERLFTFPWIKFDTFDQVLNNFYASYFAGALIIPTVQIKEQLNDIFKKETFDRSLFLKAIETFNASPESFYQRLTNILPQAFNIQNLFFLRFTHKANSDKFHLKKELHLSHQHSPHANETNEHYCRRWVSLKVLKDISKSKNEHEFDLQISDYEHDGMKYLIMSSATKDPFKENQYRSISVGLLINRQLQRKLNFLEDKTIVTQKVGVTCQRCAIKNCDVRQAPAVVLDEAAKNKKIERVVEELNSKFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJU9</accession>
    <name>A0A5C6ZJU9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_07435</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="21"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="87" mass="9573" checksum="F09F5DCEF5BA1ED0" modified="2019-11-13" version="1">MLEVITIKDVKVKIGEVCKGLRKSNDLSREDLAELLDVSSTTIQNIENGKNATLDNVLKVANHFGLLQSITKAIDTINTNQSDISLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJV2</accession>
    <name>A0A5C6ZJV2_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Co-chaperonin GroES</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">10 kDa chaperonin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Chaperonin-10</fullName>
            <shortName evidence="3">Cpn10</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">groES</name>
        <name evidence="3" type="synonym">groS</name>
        <name evidence="5" type="ORF">ESY86_05725</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 4">Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the GroES chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00320">
        <property type="entry name" value="cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.33.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00580">
        <property type="entry name" value="CH10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020818">
        <property type="entry name" value="Chaperonin_GroES"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037124">
        <property type="entry name" value="Chaperonin_GroES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018369">
        <property type="entry name" value="Chaprnonin_Cpn10_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10772">
        <property type="entry name" value="PTHR10772"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00166">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00297">
        <property type="entry name" value="CHAPERONIN10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00883">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00681">
        <property type="entry name" value="CHAPERONINS_CPN10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="91" mass="9861" checksum="616D5F96BD63049E" modified="2019-11-13" version="1">MSVNIKPLADRVLIEPVEAETKTASGIIIPDNAKEKPQKGKVIAVGKGTKDEKMTVKSGDTVLYGKYAGTELKLEGKDYLIMRESDILAIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK01</accession>
    <name>A0A5C6ZK01_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GNAT family N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_06000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004343">
        <property type="term" value="F:glucosamine 6-phosphate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006048">
        <property type="term" value="P:UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039143">
        <property type="entry name" value="GNPNAT1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13355">
        <property type="entry name" value="PTHR13355"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="10"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="153" mass="17108" checksum="F1EE0EA6E54EBE2E" modified="2019-11-13" version="1">MDSKIINETFFVKDISAKDTYAVRHPVLRAGKPMESCVFSNDDLETTFHYGLLKGSKLIGVASYFKNGNASFSEVKQYQLRGMAILENFQGQKLGDLLLKETEQMMALKSVARIWCNARVSAAGFYTKNGYSIIGTAFEIPEVGMHYVMTKVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZK93</accession>
    <name>A0A5C6ZK93_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_05655</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="1">
        <location>
            <begin position="5"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="347" mass="39071" checksum="6064A0EB7F09C2E9" modified="2019-11-13" version="1">MKKVDYIVVGCGLAGIAFCEQLRAANRSFMVFDNASQQASKVAAGLYNPVTLKRFTKVWNAKSQLDLAIPKYKALEQLLQQKLNHELPVRRKFASVEEQNSWYVASDQPVLSDFMLPKILKNANADLIAAHGFGEVLHSGRIDTSQLVPSYQSYLEERNQLERAGFEHAAVGFESGHIQYKDFESKYIVFAEGFGLAKNPFFSKLPLRGLKGEMLTIKAPNLQMDFVLKSSIFLVPLGDDLFWVGATYEHHDNTHTVSEEGKEQLLSKLKSVITCEFEIVDQVAGIRPTTKDRRPMVGRHDTHEQMFVLNGMGSRGVMISPYAAKQLFEHIELGTALDPEIDIKRFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKJ2</accession>
    <name>A0A5C6ZKJ2_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="12 13">DNA primase</fullName>
            <ecNumber evidence="12">2.7.7.101</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">dnaG</name>
        <name evidence="15" type="ORF">ESY86_01995</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="13">Binds 1 zinc ion per monomer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Monomer. Interacts with DnaB.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12 13">Belongs to the DnaG primase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.101" evidence="12"/>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990077">
        <property type="term" value="C:primosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003896">
        <property type="term" value="F:DNA primase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03364">
        <property type="entry name" value="TOPRIM_DnaG_primases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00974">
        <property type="entry name" value="DNA_primase_DnaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013264">
        <property type="entry name" value="DNA_primase_core_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037068">
        <property type="entry name" value="DNA_primase_core_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019475">
        <property type="entry name" value="DNA_primase_DnaB-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006295">
        <property type="entry name" value="DNA_primase_DnaG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036977">
        <property type="entry name" value="DNA_primase_Znf_CHC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030846">
        <property type="entry name" value="DnaG_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034151">
        <property type="entry name" value="TOPRIM_DnaG_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002694">
        <property type="entry name" value="Znf_CHC2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10410">
        <property type="entry name" value="DnaB_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08275">
        <property type="entry name" value="Toprim_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01807">
        <property type="entry name" value="zf-CHC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002811">
        <property type="entry name" value="DnaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00400">
        <property type="entry name" value="ZnF_CHCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01391">
        <property type="entry name" value="dnaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12 13" id="KW-0235">DNA replication</keyword>
    <keyword evidence="10 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1 12 13" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 12 13" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2 12 13" id="KW-0639">Primosome</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 12 13" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 12 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="8 13" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Toprim" evidence="14">
        <location>
            <begin position="259"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR002811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="TXD90757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="655" mass="75002" checksum="C5BFC2D0FC8F0F94" modified="2019-11-13" version="1">MIAKATIDHVFETARVEEVIGDFVQLKKSGSNFKGLSPFSDERSPSFMVSPVKQIWKDFSSGKGGNAITFLMEHEHFTYPEAIKYLAKKYNIEIEETEQSDEQKQEANERESMYLVNEFAQTYFQKIMLKTDQGQAVGLSYFKERGFTNETIKEFNLGYCLDDWQAFTDEALKKGYQLEFLDKTGLTIVKVDKKFDRFKGRVMFPIHSMSGRVLGFGGRILKADKKAAKYLNSPESEVYHKGKVLYGIYHAKQAIAKEDNCYLVEGYTDVIQFYQTGIENVVASSGTALTPEQIRLINRLTNNITVLFDGDAAGIRASVRGIDLILEQGMNVRVCGFPEGEDPDSFAKQNTLEELTEYLEANAKDFIQFKASLLVKEAKNDPIRKAETIREIVNSISKIPDQIKREIYIQECSKIMAISEEVLFNTLAQLNKKETQEANKSYPSKQKSFDVIKSDAPSNKVDLQFELEKKIIEILLLYGTETEDFEDLVLKETEDGALKLEPVVHHAKVFEKIYMDLQEDEMQFTNANFKTLYYNIIDTLNQTPEFSTKNFVNQLEQGLASDVTSILMDDERYRLHDWERNQIIPKGKKQSIPQLVTQTILTLRCFLIDRKVAEYQNDTLRENANTRSILEDVKDYLSLKMLLSRKLGKVVGGKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKJ3</accession>
    <name>A0A5C6ZKJ3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_05870</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="283"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="311"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="339"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="45"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="370" mass="42471" checksum="671238E43EC03D85" modified="2019-11-13" version="1">MVVFNVIFYAFIAVVCVQIYYYTVVFGRFSALKTKKAAFKTPPVSVIVCAKNEADNLKRNIPFLLSQEYPEFELILINDNSSDHTLKVMTGFQKLHENIKIVNVKPVEAFWGNKKYALTLGIKAATHETLLFTDADCSPNSSHWIAEMCVQFDQERLLVLGYGAYEKIKRSFLNRLIRFETFFTAVQYFSYATTGNAYMGVGRNLAYKRSLFFEANGFIGHIQVKSGDDDLFVNQVATKLNTAICVSEHAFTSSKPKTDFKSWILQKRRHVSTASHYKTKHKLMLGLFYVSQILFWILGTTVLILMLHWEIAVALIALRFAIQYMVLFAAAKKLNEKDLIFLLPVLEVFLFSAQMVIFIQNLISKPKYWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKL3</accession>
    <name>A0A5C6ZKL3_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 2">Adenylyl-sulfate kinase</fullName>
            <ecNumber evidence="1 2">2.7.1.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">APS kinase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">ATP adenosine-5'-phosphosulfate 3'-phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="1">Adenosine-5'-phosphosulfate kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1 3" type="primary">cysC</name>
        <name evidence="3" type="ORF">ESY86_07955</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 2">Catalyzes the synthesis of activated sulfate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 2">
            <text>adenosine 5'-phosphosulfate + ATP = 3'-phosphoadenylyl sulfate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24152"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58243"/>
            <dbReference type="ChEBI" id="CHEBI:58339"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.25"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 2">Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the APS kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.25" evidence="1 2"/>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00140">
        <property type="reaction ID" value="UER00205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004020">
        <property type="term" value="F:adenylylsulfate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070814">
        <property type="term" value="P:hydrogen sulfide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000103">
        <property type="term" value="P:sulfate assimilation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02027">
        <property type="entry name" value="APSK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00065">
        <property type="entry name" value="Adenylyl_sulf_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002891">
        <property type="entry name" value="APS_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00455">
        <property type="entry name" value="apsK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 2 3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2 3" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Phosphoserine intermediate" evidence="1">
        <location>
            <position position="106"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="32"/>
            <end position="39"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="200" mass="22666" checksum="68C511BF4B0F6977" modified="2019-11-13" version="1">MEKNIKDHDYQITKLDRNIGNKHKSFLVWFTGLSGSGKSTIANLIEQQLHNKGIKTYTLDGDNIRKGINSDLSFAPKDRTENIRRIAEVANLMVDAGVVVLAAFVSPYRKDRENIKTTVKDVNFVEVFVNTSVEECERRDVKGLYKKARAGEIENMTGISAPYEAPERPDIEIETEKETLEDSITRIMAIITPKLHLDNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKP7</accession>
    <name>A0A5C6ZKP7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Nucleoside deaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_09200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016192">
        <property type="entry name" value="APOBEC/CMP_deaminase_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00903">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="156" mass="17466" checksum="8CBBCE6527A56D53" modified="2019-11-13" version="1">MSKDKFMQEAVKAALEGMTKNAGGPFGCVIVKDGQIVGRGYNKVTSTNDPTAHGEVMAIRDACKNLDSFQLDGCELYTSCEPCPMCLGAIYWARVEKVYYGSTQVDAANIGFDDQFIYDEIPLPYAERRIPFIQVAHEIAMEPFNTWRAKEDKIDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKQ9</accession>
    <name>A0A5C6ZKQ9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_07415</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-I restriction system S methylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.220.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000055">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044946">
        <property type="entry name" value="Restrct_endonuc_typeI_TRD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01420">
        <property type="entry name" value="Methylase_S"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0680">Restriction system</keyword>
    <feature type="domain" description="Methylase_S" evidence="4">
        <location>
            <begin position="14"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="domain" description="Methylase_S" evidence="4">
        <location>
            <begin position="264"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD89607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="432" mass="49138" checksum="FDD00C6F44355201" modified="2019-11-13" version="1">MKEYISHPKLGKIPSNWKSSKLSEIVNLEHGFQFRKEDFTESGIPVIKINNIIGNDLNLDNLSFIDSSRLEEFTRFLIKKDDILMSLTGNIGRVLEVGSIQRDFVQNYRVGKFVPVNSNELYNRYIKYLLSSPLVLSQFFKFSNQSAQANFGKQDMDKVWVTIPTSPSEQEKIANILSTVDAKIEVISQQITETQELKKGLMQRLLTKGIGHTEFKDSSLGEIPKCWDVIPIYELRNKQDRYGFTGGPFGSDLKSEHYTENGVKIIQLQNIGEGEFIDKGTTYTSKEKADELFSCNIFPNEIILAKMAPVARCCKVPSTDERYVMCSDGIRLSVDTNKFDNEFVYQALNSKYFRDEAESKSTGTTRARIGLKDLKLIPILVPKYIDEQKKLANILSTVDGKLDLLSEKKTTYQELKQGLMQQLLTGKVRVNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKX3</accession>
    <name>A0A5C6ZKX3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">RNA polymerase sigma factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_05885</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="6">
        <location>
            <begin position="24"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4" evidence="7">
        <location>
            <begin position="125"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD90265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="178" mass="20644" checksum="64070B4E83C8DDC8" modified="2019-11-13" version="1">MSTPIEKNIVSLLEQGDERALDLLYEYYGDSLYGVILQVTSNEELAQDALQETFIKVWKNGKKYDSSKAKLFTWLYRIAKNTAIDKLRSFKNRFEKEVQIDKSDVYILPTASLNQDVMDLKEHVARLEDKYQIVLKALFFEGMTQQEASEELDIPLGTIKSRLKIGLRELKKVYVPKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL14</accession>
    <name>A0A5C6ZL14_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">VIT family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_03000</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005384">
        <property type="term" value="F:manganese ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030026">
        <property type="term" value="P:cellular manganese ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008217">
        <property type="entry name" value="Ccc1_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31851">
        <property type="entry name" value="PTHR31851"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01988">
        <property type="entry name" value="VIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="151"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="180"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="209"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD90937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="235" mass="25122" checksum="BB834E1CBE04909E" modified="2019-11-13" version="1">MSEFEDDYLDNHYIHRSNWLRAAVLGANDGILSTASLAIGVAAASDFRAPVILATVAGLVAGTLSMAAGEYVSVSSQTDVEKADIERERLELEEMPEIELLRLAEIYENRGLKKETALIVAKELTEKDALAAHVRDELGINEMSQAKPIQAAFASGAAFTVGGVLPLLVVLFLPLKNMEYYLYGSAILFLIVLGSLAAKTGGSNVLKAIIRVTFWGTVAMGLTALVGYLFGVSLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL24</accession>
    <name>A0A5C6ZL24_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="49"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="295" mass="33403" checksum="B7BD1E61EA7716C2" modified="2019-11-13" version="1">MTTSIRIATLILMTISTTSSFGLIRETHLLETSNPKPFIVETIGQGKPILYLPGFATPGSVWKETVESLNLERKSHLFSYAGFNGNAPIAMPWYSSIKKAIIEYIIVNDMSNLIIVGHSMGGNLAVDIASEIPSRVSKIIIVEALPCMREVMMPNVPAESLYYDSPYNKQMLEMDAQQFKNMATMMASNMTLIENKKDIITNWILEADRETWVYGYTDLLKLDLRTSLSKVTCETLILGASFPDVKIAKAHYENQYSNLSNKKILMATNSKHFLMFDQAEWFYKTVNDFLVHEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL29</accession>
    <name>A0A5C6ZL29_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">3'(2'),5'-bisphosphate nucleotidase CysQ</fullName>
            <ecNumber evidence="3">3.1.3.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">3'(2'),5-bisphosphonucleoside 3'(2')-phosphohydrolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">3'-phosphoadenosine 5'-phosphate phosphatase</fullName>
            <shortName evidence="3">PAP phosphatase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 4" type="primary">cysQ</name>
        <name evidence="4" type="ORF">ESY86_07965</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Converts adenosine-3',5'-bisphosphate (PAP) to AMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>adenosine 3',5'-bisphosphate + H2O = AMP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10040"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="3.1.3.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Peripheral membrane protein</topology>
            <orientation evidence="3">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the inositol monophosphatase superfamily. CysQ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.7" evidence="3"/>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008441">
        <property type="term" value="F:3'(2'),5'-bisphosphate nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046855">
        <property type="term" value="P:inositol phosphate dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006790">
        <property type="term" value="P:sulfur compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02095">
        <property type="entry name" value="CysQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006240">
        <property type="entry name" value="CysQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020583">
        <property type="entry name" value="Inositol_monoP_metal-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00377">
        <property type="entry name" value="IMPHPHTASES"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01331">
        <property type="entry name" value="bisphos_cysQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00629">
        <property type="entry name" value="IMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="90"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="68"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="270" mass="29797" checksum="F241AA8CDD8F673D" modified="2019-11-13" version="1">MTGIKINNNLKTAIEASLKAGEVIMQVYDTAFDVELKADKSPLTEADKQANDIINTFLLPTKIPIISEENKQTDFSIRKSWNQCWVVDPVDGTKEFIKRNGEFTVNIALVKDGKPELGVIYVPATKILYFADVTRHEAYKAILETHDSAIDEILASCTLLKPKGEHSATVEVVGSRSHMSQETVDYIDELKEKGKAVEIVSKGSSLKFCLVAEGSADVYPRFAPTMEWDTAAGQAICNAVGLAVISKDTNQSLLYNKENLLNPWFLVAKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZL54</accession>
    <name>A0A5C6ZL54_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MBL fold metallo-hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_04180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="87"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="522" mass="59669" checksum="3833A6CC891746EA" modified="2019-11-13" version="1">MKTFIAEDFVSVYRKNANGDFNKSDMLIFGDPFEVLEYSTAHKKTKIRVLNRFFSPYIGYVKGKPKTMNKGALKMSMVDVQQGDGMVLQTPDDKIIIIDGGHNVLFARHFAARFQHKKSSSSNPLPVEAIIITHGDADHFKGLNEFVKAENYRGARRFKKVAIQPKRILHNGLIKRPSSLPEEQRLGKTAIHNNELYITDLVKDPRSIPLDEQNAVFKSWSKSLDHWEQRAAIDFKTVHHGMDEKDVFDFLEEEGIAVDLHGPFSRKVTQNGQVVDALQFLHKQAPDPELKTHEFDISTHQHSASHTINGHSLAFRLSYGNVRINFTGDLNEESLQILDKTLDDRLLKAEILKAPHHGSHEFDFKTLQKMAPIVSLVSSGDDSEFWEYMHPRANLLCALGKICREDQGIIFSTELAAFFKHKDLSFKNSDLKDFFKNSDKDSYTKAELMTLFSESITDSALKKMVFTGFERTNFGLIELRTDGERVLVFTHSGKPWVKEAYTFTVKMINRKRIVSFESLKIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLB6</accession>
    <name>A0A5C6ZLB6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tetratricopeptide repeat protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_00685</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13174">
        <property type="entry name" value="TPR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="167"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD91138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="255" mass="27897" checksum="BE9765432044032B" modified="2019-11-13" version="1">MATYKKRGYKPKTEKEKTEVIEDNSTTAEVFNTLDEGANKAELWVGKNQKGIFIIIGVAAVILLGYLAYNKFIAGPKAEEAMNEMFTAQKYFNQAVTGESADSLYTLALKGGEGKFGMVDIASEYSGTPAGNLANYYAGMAYLNTKDYTNAVKYLSDFTTDDAVLGPVAKGGIGDSFVQLNQLEDALDYYEKAISASTNDYTTPMYLFKAGNVAQSLGQKDKALQYFERIQQEFSDSDQAKNIEVFIGRAEASAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLF1</accession>
    <name>A0A5C6ZLF1_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="9 10">Multifunctional fusion protein</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="9">Protein translocase subunit SecD</fullName>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="10">Protein-export membrane protein SecF</fullName>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="9" type="primary">secD</name>
        <name evidence="10" type="synonym">secF</name>
        <name evidence="11" type="ORF">ESY86_04610</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the SecD/SecF family. SecD subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the SecD/SecF family. SecF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015450">
        <property type="term" value="F:protein-transporting ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043952">
        <property type="term" value="P:protein transport by the Sec complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01463_B">
        <property type="entry name" value="SecD_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01464_B">
        <property type="entry name" value="SecF_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005791">
        <property type="entry name" value="SecD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022813">
        <property type="entry name" value="SecD/SecF_arch_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022645">
        <property type="entry name" value="SecD/SecF_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022646">
        <property type="entry name" value="SecD/SecF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005665">
        <property type="entry name" value="SecF_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30081">
        <property type="entry name" value="PTHR30081"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07549">
        <property type="entry name" value="Sec_GG"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02355">
        <property type="entry name" value="SecD_SecF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01755">
        <property type="entry name" value="SECFTRNLCASE"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00916">
        <property type="entry name" value="2A0604s01"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00966">
        <property type="entry name" value="3a0501s07"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01129">
        <property type="entry name" value="secD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="505"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="529"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="555"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="594"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="630"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="683"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="817"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="841"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="876"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="927"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="951"/>
            <end position="975"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD90041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="992" mass="108271" checksum="07B4AA87FF80FDEB" modified="2019-11-13" version="1">MQNKGLVKLFALLFGLVSIYQLAFTFKSNQLDEDAKTYAVNKYDDPEQINDAEVHYMDSIANREVYDIGIATFTGNEVKEKAMNLGLDLKGGLNVILQISVRDILQGLSNNSKDPAFNKALTDAVEIQKDAQEPYLESFFTAWERVKGDKKLASPDIFANRNMDDVIDISMSDDDVKSKLEEKVDESIISAFEVLRKRIDQFGVTSPNIQRLGNSGRVLVELPGVKDIKRATELITTTAQLQFWDVETPQVLSDFFGATNETLKTQLGTETTETVTEQDSTATNQDSKIDDLLGETSTDSISTTGANPFFEIVGPPRSGGMLALKLEDKETMKSYLAMDAVRANLPAELRYTKFAFGLPSLDPETNVEYVDLYALKGNRDNEPDLSGGVVTDARQSYSQTNRPTVSMQMNAKGSKIWEEMTGRASAQGSQIAIVLDDIVYSAPTASNGAISGGNTEISGNFTVLEATDLANVLRAGKLPARAEIIQADQVGPSLGKEAIESGTKSFLLALSLVLIWMILYYGKAGLAADIALIFNIILIFGVLSGLGAVLTLPGLAGIVLTIGMSVDANVLIFERIREELNKGKAQKQAIKDGFSNALSSILDANITTGLTALILFIFGTGPIKGFATTLLIGIVTSLFTAIFITRLLVDWYANKNKTLDFSTSITKNLFKNNSINFIGKRKIAYVVSGIMIVVSLISLFTNKLDQGIDFVGGRTYQVRFPEAVNAGDVDKDLTVLFKSVEVKTIGGDHQLKISTKYKVDENSVDIDEEIQRMLYGGLESHLQGMSYPDFAAGKDGLGKVLSSKVSPTIADDIKTESFWAVLGSLLVVFLYILLRFKRWQFSLGAVAAVFHDVIILLGVFSLLYKFMPFSMEIDQAFIAAVLTVIGYSLNDTVVVFDRIREELAEKEGFKGGFNINTAINSTLSRTLNTSLTTLVVLFAMFLFGAQSLKDLLFALIVGVIIGTYSSVFIATPLMYDTLKDKGKAPEGEADNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLG7</accession>
    <name>A0A5C6ZLG7_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Signal recognition particle protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Fifty-four homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ffh</name>
        <name evidence="9" type="ORF">ESY86_04730</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="7">The SRP-RNC complex is targeted to the cytoplasmic membrane.</text>
    </comment>
    <comment type="domain">
        <text evidence="7">Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the GTP-binding SRP family. SRP54 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048500">
        <property type="term" value="C:signal recognition particle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00306">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036891">
        <property type="entry name" value="Signal_recog_part_SRP54_M_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013822">
        <property type="entry name" value="Signal_recog_particl_SRP54_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004125">
        <property type="entry name" value="Signal_recog_particle_SRP54_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004780">
        <property type="entry name" value="SRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022941">
        <property type="entry name" value="SRP54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042101">
        <property type="entry name" value="SRP54_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11564">
        <property type="entry name" value="PTHR11564"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11564:SF7">
        <property type="entry name" value="PTHR11564:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02881">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02978">
        <property type="entry name" value="SRP_SPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00963">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47446">
        <property type="entry name" value="SSF47446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00959">
        <property type="entry name" value="ffh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00300">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0733">Signal recognition particle</keyword>
    <feature type="domain" description="SRP54" evidence="8">
        <location>
            <begin position="268"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="106"/>
            <end position="113"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="189"/>
            <end position="193"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="247"/>
            <end position="250"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD90061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="443" mass="48096" checksum="B7B1803F9A8A9A0B" modified="2019-11-13" version="1">MFNSLSEKLDKALHVLKGHGSISEVNVAETLKEVRRALLDADVNFKIAKEFTNTVKEKAMGQNVLTSLQPGQLMVKLVKDELTQLMGGDAEGINLSGDPTVILMSGLQGSGKTTFSGKLANYLKTKKTKRPLLVACDVYRPAAVDQLHVVGGQIGVEVYSDKGNTDPVAIAKAGIAHAKAKGLNVVIIDTAGRLAVDEAMMAEISNIHKAIQPQETLFVVDAMTGQDAVNTAKSFNDILNFDGVILTKLDGDTRGGAAISIKSVVNKPIKFIGTGEKMEAIDVFYPSRMADRILGMGDVVSLVERAQEQYDEVEARKIQKKIAKNQFGFDDFLKQIQQIKKMGNMKDLIGMIPGAGKMMKDVDIDDDAFMGIEAIIHSMTPEERSNPTVINASRKKRIGKGSGTSVQEVNQLLKQFNQMSKMMKMMQGGKGKAMMQAMKGGMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLJ9</accession>
    <name>A0A5C6ZLJ9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TetR/AcrR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_04965</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="7"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="204" mass="23442" checksum="9BDF24FC1CF83FDF" modified="2019-11-13" version="1">MAKTKDENTEEQILVAAKTVFQTKGMDGARMQHIADEAGINKAMLHYYFRSKQLLFEAVFNQAFSLLAPQLNIILNDESSIEDKVKNFTVNYTTFMMKHPYLPNFIIQELNRNEDFIVKLKENTGFPNLDKFKAQVDAEINDGLLNPIDADQLFVNIIALNIFPFLGKPLIKAFTNKDEQDYETFVESRKTEVANFIINSIKPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLL1</accession>
    <name>A0A5C6ZLL1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">T9SS type A sorting domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00825</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026444">
        <property type="entry name" value="Secre_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18962">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04183">
        <property type="entry name" value="Por_Secre_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Por_Secre_tail" evidence="1">
        <location>
            <begin position="524"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="592" mass="65548" checksum="879E841DD3CB9AD2" modified="2019-11-13" version="1">MKQQYLIIVLILSSLLGFSQLNLRNEAFMFVSNEVVFVNNAVNLSEENSKIYLRNEGQLLQGNGTTGNSGIGALSVYQNGNTNQFAYNYWASPVGNPSAANGNEPARVDLIDDATGLTSSADALFSSNHNGISSPLTISRRWLYTFIASDEYAEWNSINESSPIPTGLGFTMKGIGTDPTGSQLYDFRGKPNNGTITAEIAANQYTLIGNPYPSALDALKLIHDPQNVNINAPTTTGVLYYWDQRPTTHFTSDYVGGYATYTISDAGLESFVHATFSAYDSSGNASPLPEAGLKIAQRYIPIGQGFMVEGSAATSSEALVYLKNEHRVFEKESAGYSTFFRATEANSNDFTEENTAYNAWGLNIVPEDYKRFRLNVIFNSEFTRQLLQNFHHSATEAFDYGLEAKLGSTADTEVSWLLNEVPYVIQAHAFDTQLKIPLAIKVASNQPVDFSLFDVQRFDDAQPIYLHDKLTNIYADLTQQNYSINLEAGNYPSRFEITFQQASLAIETVAASQFEVFQNRNSQELVILNPQQKGIQQLSLYDVNGKLILHQANLDTKKRYTLSTENLSAAVYVFSIGLESKQNISKKVIIKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLL9</accession>
    <name>A0A5C6ZLL9_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Acetate kinase</fullName>
            <ecNumber evidence="6">2.7.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Acetokinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ackA</name>
        <name evidence="8" type="ORF">ESY86_05125</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>acetate + ATP = acetyl phosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:11352"/>
            <dbReference type="ChEBI" id="CHEBI:22191"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="6">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="6">Mg(2+). Can also accept Mn(2+).</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the acetokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.1" evidence="6"/>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00340">
        <property type="reaction ID" value="UER00458"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008776">
        <property type="term" value="F:acetate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006085">
        <property type="term" value="P:acetyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00020">
        <property type="entry name" value="Acetate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004372">
        <property type="entry name" value="Ac/propionate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000890">
        <property type="entry name" value="Aliphatic_acid_kin_short-chain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023865">
        <property type="entry name" value="Aliphatic_acid_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21060">
        <property type="entry name" value="PTHR21060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00871">
        <property type="entry name" value="Acetate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000722">
        <property type="entry name" value="Acetate_prop_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00471">
        <property type="entry name" value="ACETATEKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00016">
        <property type="entry name" value="ackA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01075">
        <property type="entry name" value="ACETATE_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01076">
        <property type="entry name" value="ACETATE_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="6">
        <location>
            <position position="147"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="7"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="205"/>
            <end position="209"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="279"/>
            <end position="281"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="327"/>
            <end position="331"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="381"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="6">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="6">
        <location>
            <position position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD90131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="394" mass="43255" checksum="8A4876FFB6D762D2" modified="2019-11-13" version="1">MNILVINSGSSSIKFQLIQMPSEALICSGLVERIGHKDAILNYTRSNTSIQQIGRIETHQEALHKILDLLLDAETGVIQKSNEIEVVGHRVVHGGNSFSETALITAEVKQEIQQYAALAPLHNPSNLVGILVAEAFFPLARQVAVFDTAFHQSIPEKAKKYAIPNNFYEDHGIQLYGFHGTSHQYVSEQAIAYLQLQRSKIISIHLGNGCSITAIMDGKSIDHSMGFSPSPGLIMGTRSGDIDHSIVFHLVNNLGYSLNEVDKLLNKKSGMLGLTGYSDLRDIQAEAEKGNAHCVLALAMNAYRIKKYIGAYIAAMNGLDAIVFTAGIGENSSTLRQLICADMDCFNIALDDSKNEFRTQNIREIHTDASKVKILVVPTNEELEIAKQAFQLVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLT3</accession>
    <name>A0A5C6ZLT3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycerophosphodiester phosphodiesterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_01315</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030395">
        <property type="entry name" value="GP_PDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03009">
        <property type="entry name" value="GDPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="SSF51695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51704">
        <property type="entry name" value="GP_PDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GP-PDE" evidence="1">
        <location>
            <begin position="6"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="244" mass="27910" checksum="C95D207E1ACCFE1E" modified="2019-11-13" version="1">MVFANTKVVAHRGAWKAHKLPENSIASLKQAIKMNCAGSEFDVRMTSDEVLIVAHDPKYHEMLIEETTYADLSKIKLSNGEMLPKLKDIIIAGMEGNDSTGLVCEIKPSKIASRNKDITNKTLQLVKALNAEAYVSYYISFDYDIIKHIKKLQPESKVLYLDGSKAPKDLSKDQIDGLDYAFFKMKKNPQWIKEAKDYKLILNAWTVNKIEDIDWLLDHGFDYITTNEPELVFKRINERANHED</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLT7</accession>
    <name>A0A5C6ZLT7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GHKL domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_01385</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="142"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="66"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD91268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="370" mass="41781" checksum="10D040EEAFDE83A9" modified="2019-11-13" version="1">MEKGGKSLKLINANKELAFQNEEKEKRAAELVIANKELAFQNEEKEKRAAELVIANKELVFQSEEKEKRAAELVNANKELAFQNEEKGKRAAELGIANKALVFQNKEKKKRAVELSDSNKEVDELEKRVKERTEDLESFSYSVSHDLRAPLRAINGYAKMLDEDYSNVLDAEGKRFLVEVRNNANKMGVLIDDLLTFSRLGRKGITNAKVDMNKLFETVLSEISQNTAHHAEIKYSNLLPAVADRNLLQQVISNLLSNAIKYSSKKEKPEIDITSKYKNGMQVYAISDNGVGFDMHYVNKLFGVFQRLHSDEEFPGTGVGLAIVQRIIHKHNGNVWAEAKEGQGATFYFSLPAIDEKPVVSQSFNLTKSW</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLX7</accession>
    <name>A0A5C6ZLX7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">MCE family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_00370</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003399">
        <property type="entry name" value="Mce/MlaD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02470">
        <property type="entry name" value="MlaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="domain" description="MlaD" evidence="2">
        <location>
            <begin position="37"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD91086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="322" mass="35339" checksum="0CAE82413BB27466" modified="2019-11-13" version="1">MKITREVKTAILVISGIVLFIFLFSYLKGENLLDSSRTYYAVYDNVEGLTPSTAITINGFQVGKVKSITFKGDGSAKLLVTLMIDNDFQFSKNSTAQIHDLGLIGGKGVEIIPIFDGAPVAASGDYLKTNVKAGITELVNKRLTPLQEKIEAVMVNVDSLLTNVNVLFDEDTKNNITGSIEDLSATISNFKEASSSVNSLIASNDDKLGRTIANFENTSANFSKLSDSLAKIDLSRTIEDFQNTITRVDNLLANVENGNGSIGKLLRDESLYNNLEGASQQLKQLLEDIKLNPKRYVHFSVFGKKDKRYDAEGNEIEETDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZM74</accession>
    <name>A0A5C6ZM74_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphatase PAP2 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_00070</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036938">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxi_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000326">
        <property type="entry name" value="P_Acid_Pase_2/haloperoxidase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01569">
        <property type="entry name" value="PAP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00014">
        <property type="entry name" value="acidPPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48317">
        <property type="entry name" value="SSF48317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="216"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="acidPPc" evidence="2">
        <location>
            <begin position="118"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD91032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="245" mass="28063" checksum="7059D9D06F90C3B8" modified="2019-11-13" version="1">MLKQLKALITNFKAFLSHKFRKYDIKLPYFIVILIAFLIVIACVKLFVELTESLKTDVLAQFDVEVTNYVMSFKSSHLTNYFIAVTNIGDVYGYLVIFGACSLLFYLIFKSWSHVLQLSLVLFLALSSNLALKEMVDRQRPTLEHLVTVETLSYPSGHAMTAMAFYGFLIYMFSTFRIGLFFKIFIAIALSLFILSIGISRIYLGVHFPSDVAGGFIAGFFWVIFCVLTFNLIKLFRRDPESKKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMC2</accession>
    <name>A0A5C6ZMC2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Potassium transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_04850</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015079">
        <property type="term" value="F:potassium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015299">
        <property type="term" value="F:solute:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004771">
        <property type="entry name" value="K/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006036">
        <property type="entry name" value="K_uptake_TrkA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02254">
        <property type="entry name" value="TrkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00335">
        <property type="entry name" value="KUPTAKETRKA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00932">
        <property type="entry name" value="2a37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51201">
        <property type="entry name" value="RCK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0630">Potassium</keyword>
    <keyword evidence="2" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="115"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="144"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="197"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="229"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="284"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="309"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="339"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="373"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="RCK N-terminal" evidence="8">
        <location>
            <begin position="418"/>
            <end position="539"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD90083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="616" mass="68026" checksum="37DFE136C4281F12" modified="2019-11-13" version="1">MSGSFLLQAIVFLAGAVICVPLAKKLGLSSVIGYLFGGMLIGPYILGFVGHEGEDIMEFAEFGVVMMLFLIGLEIEPRSFWKMRKTILGLGMSQVFGTILLTYLVCYAFGLDWNIALTIAMAVALSSTAITLQTNKEKGLMNTIYGASSFSILLFQDIIVIVMLGVLPLLSNVSATLPEEGTGTTHVNLLNNLPLPLQAVGIFTSIVLIVLAGRYVIVPVLRLVARSGVRELLVASALLIVVAISYLMELVGLSPALGAFLGGVVLATSEFKHELESTLDPIKGLLLGLFFMAVGASINFIVIGEQPLLITSLVLGVIALKAFVLFVVGWIFKLKIDQRLLLTVGLAQIGEFAFVVLSFAFQLNIFTREQLDILLVVTALTMTLTPIIWILNERLVLPRVGTKESEKRPMDQIEKQHKVLLLGFGHFGSTVGRFLRAHGVQTTVIDSNSNRVDYLRKMGFEVYYGDVSRIDLLESAGIADADFLISAIDDPDVNLSLMRKLKEKYPKLKLMVRAKNRYDAYEFFNMGIENIYRESFETSVRLASDVLYFMGFDQTATEEQAQKFIRLDNESFSRLAASANNRKDYIFKARQEIALQERLLDEDLNLGSSDLAKHKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMC3</accession>
    <name>A0A5C6ZMC3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DUF4870 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_02385</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019109">
        <property type="entry name" value="DUF4870"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09685">
        <property type="entry name" value="DUF4870"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="domain" description="HTH cro/C1-type" evidence="2">
        <location>
            <begin position="10"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="526" mass="59938" checksum="23D0E0567112F4E9" modified="2019-11-13" version="1">MEKQTIGKKLAYQRKLKGYTQDILSEKSNVAIRTIQRIEKDEVNPQLQTIKLLADALKIEVDDLIILENPKEEALQNKWLLFLHGSPLLGFIFPFSVLFPLFIWLHKRDDNPIYNQHGIKIINFQLSVTILYILAFISLVTVEGWGFLFFIAVVPFNILVISYNLFKAITAQKCYYPLSFPFLKTNTKKHLKKPFQLLSITAILTIMILCVSFTNKNKYYKGIISNNLSDSILTSKQTLEVNKIAFYLQDGVEVLDFSGPMEVFAYAGYEIFIVSKTTHPITTQGIMKIIPQYSIKNAPSADILAFFGGNSSEAYKDIEVINWVKSQNSTKYYFSVCTGAFILAESDILKGKTATTFHNALDEFEYKYPETTVLKNIRFVDNGNVITTAGISAGIDGALHLVAKLKGFNAARKVAYYMEYDKWIPGEGLILSDDNPYKNFIGNGKFDDYVGIYEFQNNTDIILKVNSNEQSLYAKVNGRNYPIFFIKDNIFLNVDEEKIIFERNSNDEILGFKAAEKNSKFYAKLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMX7</accession>
    <name>A0A5C6ZMX7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">GxxExxY protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_06035</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026350">
        <property type="entry name" value="GxxExxY"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13366">
        <property type="entry name" value="PDDEXK_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04256">
        <property type="entry name" value="GxxExxY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="124" mass="14323" checksum="A210A1347A973D8D" modified="2019-11-13" version="1">MPNLIYKEDVYKIIGICMEVHNQLGRGFNEAVYADALEIEFVQNEMIYAREIKYTINYKGNILPHYYKADFIINDSVVLEIKAISSLTDSHIKQTLNYLAASKLKLGLLINFGEDSLKYKRIIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN31</accession>
    <name>A0A5C6ZN31_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Rhodanese-like domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_04900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="31"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="117" mass="13374" checksum="E87A7B3AF2D00690" modified="2019-11-13" version="1">MTLFSMIFGSKSAQTDTIKVLSASAFKEAISNKKVELVDVRTAQEFKKGAIEKAKNIDFFQQNKFNTAFEKLDKDKPVYLYCQSGNRSGQASRKLDAMGFKEIYDFKGGYSRWPYKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN58</accession>
    <name>A0A5C6ZN58_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Biopolymer transporter ExbD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_02090</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the ExbD/TolR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003400">
        <property type="entry name" value="ExbD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30558">
        <property type="entry name" value="PTHR30558"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02472">
        <property type="entry name" value="ExbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD90774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="201" mass="22527" checksum="236592E31A71AB60" modified="2019-11-13" version="1">MAKRAAPEVNAGSMADIAFLLLIFFLVTTTIPKDSGIPRKLPPIDDTEQDVIIKEKNVFTVLINNKDQLLVEDQVMELKDVRPAAIAFLDNGGDGSCSYCKGKRDPKSSDNPDKAIISLKNERETSYAAYISVQNELVAAYNTLRNIRAKEIGPKRGFAEMDFVEMETNLKDPKFNGNKEKLKDLVDQIRTEYPEKLSEVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNP1</accession>
    <name>A0A5C6ZNP1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADP-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03035</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002364">
        <property type="entry name" value="Quin_OxRdtase/zeta-crystal_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01162">
        <property type="entry name" value="QOR_ZETA_CRYSTAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="10"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="327" mass="35501" checksum="979AE7BA8CEA8EC7" modified="2019-11-13" version="1">MKALQITKYGAIKDSLSIKKIEKPTITSNDILIEVKAASLNPIDYKLVEGHLKDMVPLNFPITIGYDLSGVVVEKGGDVGNFEIGDEVYSRVPQEQMGTVAEFVAVTSDLVAKKPENISFEEAAGLPLTGLTAIQALESVGIKENDRILIHAGSGGVGSLAIQYAKAKGAIVYTTTSSKNVDWVKALGADRVIDYKTEDYKEVANNLDIVFDTLGDDYTFDAFEIIKEGGSVTTIVGPPDEETAKQMGMSDYKLPEKLSKLIEKKSATYKLTWMQPNATQLDTITAMVENGDIKPIVDLIYPFEDGIDAYEYLATGRAQGKVIISLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZP99</accession>
    <name>A0A5C6ZP99_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_01270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="1">
        <location>
            <begin position="235"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="346" mass="40223" checksum="C1FC4603DA54C7E1" modified="2019-11-13" version="1">MINIRIKEKTLKNSILAIQKQLGGELSEKWGEYVLEVDNDIAKGCMRFFNFNWGVSLVEINIIFFEEVTIATDISLVKPIHFLYCLNGSTKHRFKNEESFKELEQYHTAILAGCDASIEHVSLFPKGLHIELCSIQIKRLRFLKKRNNNVDYLSDKLNALFVNNNKEDNFSYYGSIDLKMADHVERLQNIDSEGIIRTLQMEGEVQQILSLFIEQHNNSENNIKNLVNLSKKELQTIRRQVEKIVEEPSKNYSLSSISRISGLSQAKLQEGFKFLYGKTVTEYIRHVRLEEARELISTSDLNISEIVYSIGFTSRSYFSKIFKEKYDVTPNDFRKEVHTLNIEKNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZPD9</accession>
    <name>A0A5C6ZPD9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="10">DEAD/DEAH box helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ESY86_03905</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 10" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Q_MOTIF" evidence="9">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="32"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="219"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="374"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="5">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="388"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD90520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="411" mass="46219" checksum="CD90E46D43B1A5EC" modified="2019-11-13" version="1">MSFKDLKIIKPLLRAVAEAGYDNPTLIQEQTIPLVLEKKDVIASAQTGTGKTAAFALPILQLLYDRQDAPKKGKTVKALVISPTRELAQQIGKNFKTYGSHTNLKSTVIFGGTGIEPQIDMLTKGVDIVVATPGRLLDLHKQDQINLDHVEILVLDEADLMLDMGFIDDVRKIERLCPEDKQTLLFSATMPFKVEDLAKTILNSPERIEVTPTSSAAKNVSQVLYYVPKKNKIELCLHLMRNTIKGSTLIFRRTKFGVDKLEQTLTTNGYKVERLHGDRSQNERQSALNKFKHGEVNILIATDVAARGIDIDELDAVLNFDLPSKPETYVHRIGRTGRAEHFGKSYSMCSADEKAYVQNIQHLINVQIPVEENHPYPLNPKEQPIVHKKKGSKYKKGRKGDGSKKKKKRWY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZQ11</accession>
    <name>A0A5C6ZQ11_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">50S ribosomal protein L13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 6 7" type="primary">rplM</name>
        <name evidence="7" type="ORF">ESY86_02025</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 6">This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the universal ribosomal protein uL13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00392">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01366">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005822">
        <property type="entry name" value="Ribosomal_L13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005823">
        <property type="entry name" value="Ribosomal_L13_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023563">
        <property type="entry name" value="Ribosomal_L13_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036899">
        <property type="entry name" value="Ribosomal_L13_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545">
        <property type="entry name" value="PTHR11545"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00572">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002181">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52161">
        <property type="entry name" value="SSF52161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01066">
        <property type="entry name" value="rplM_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00783">
        <property type="entry name" value="RIBOSOMAL_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD90763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="151" mass="16746" checksum="B0FC9FD14F6280E8" modified="2019-11-13" version="1">MDTLSYKTISANKATVNKEWVLVDAADQTLGRLASRVAILLRGKHKPNFTPHVDCGDNVIVINAEKINLTGNKWNDKTYIRHTGYPGGQKSLTATELFGKDPTRVVEKSVKGMLPKNKLGAELFRNLNVVTGPTHKHSAQKPRTMKLNEIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-05-25" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZQ77</accession>
    <name>A0A5C6ZQ77_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Response regulator transcription factor</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_02360</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="6"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="129"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="129"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="226" mass="26117" checksum="3FD0D7ECCCFF269F" modified="2019-11-13" version="1">MDKPITILLAEDEPALGQIIKESLETRHFKVLLCANGETALETYRNQEPELLVLDVMMPKKDGFTLAKEIRAIDEQIPIIFLTAKSQTQDVVEGFSIGGNDYLKKPFSMEELIVRIDNLLHRKTLQITSELLEIGKYHFNFPKQLLFFENASVQLTHREAHLLFHLVKNKNKVLDRSLILNKLWGNDDFFSARSMDVFISKLRKKLQQDAEVQIINVRGFGYKLVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZQG7</accession>
    <name>A0A5C6ZQG7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_00875</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="144" mass="16746" checksum="713E8D0CADD22C7A" modified="2019-11-13" version="1">MGIINYFDLEDSELFVFDEFISNQIKEGVVIEPKHNELLNEYIQKLFSGKNMVYVSNRAKSYSVNPMIYTEAQKIPNLVAIAMIPDTALMRKNAEFEKEFYDKPYAIFENLNDAIRWVHQIVSKENAKDDVAREKNLKQGSESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZA37</accession>
    <name>A0A5C6ZA37_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000041">
        <property type="protein sequence ID" value="TXD86725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023033177" evidence="1">
        <location>
            <begin position="22"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="179" mass="20165" checksum="AC30E020ED9BD0BF" modified="2019-11-13" version="1">MKKLILLLFVLSLLSTISCNNDDDNSTQNLIDQLPPETQTGENTFGCLLDGEPFIPGGGTNPLDCVYQFVNGEYYFGLQGNKRNENNNLITIALSTNELEIEQGLSYNLLNNISGNAQGYFSISTNFNFTSENHTELLMITKLDQINQIVSGTFWFDIEDQNGTVHEIREGRFDMQYTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAW8</accession>
    <name>A0A5C6ZAW8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HipA domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_18010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000029">
        <property type="protein sequence ID" value="TXD87123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012893">
        <property type="entry name" value="HipA-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07804">
        <property type="entry name" value="HipA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HipA_C" evidence="2">
        <location>
            <begin position="52"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="313" mass="36075" checksum="5DCF0495BBF22B33" modified="2019-11-13" version="1">MNRCPITYELCGTDRYSAKGLRMIAPKLTYLNDLPYTAAELRQEAANRAKKLSIQGVQPKLSAAISIVDQEFKIVDQFGTYIIKPQNDLFPELPENEDVTMRMAKVFGLEVPFHGMLYGKDDSLSYFIKRFDRYGKGKKLATEDFAQLTGNTRDTKYRFTMEKLIPVLDDYCSFPAIEKADFFKRVLFCYVTGNEDMHLKNFSLITKNGTITLTPVYDYLNSTIAIKNPEEEIALTLKGKKSNLKASDFINYYAKERLQLNEKTIATILEQLNKATPKWKELLEISFLSNEMKEKYLILLETRIEMIGSFDKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZAX0</accession>
    <name>A0A5C6ZAX0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_19090</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000036">
        <property type="protein sequence ID" value="TXD86862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022659851" evidence="2">
        <location>
            <begin position="19"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="313" mass="35330" checksum="ABC5B7D70B5C0D59" modified="2019-11-13" version="1">MKKMLLIALIFGASNLFAQQQQDSILVKEIPTIKNNVFQQRQEINSLTKKLNNQQYILNQQKKGLETLNLKSEKQEIIIDSLNQLIKYNSQNIVTNSTELGTKIKQTGENANSKISELDSNLDKNRLYWIIATLATLLLGGLVYWLLGKRIQSSKTDVETQIKNTKTALEEESVKLDNKLVEVLETQLKLKKEETKVQATTSNEKADHSLALKVADEVIRIQKNLSRMDESTKGLKQLGSSVKRIQDNFASNGYELVEMLGKEYNEGMKVTANFTPSEDLETGKQIISRIIKPQVNFKGEMIQAAQIEVSVGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZB70</accession>
    <name>A0A5C6ZB70_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Azurin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_19135</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000037">
        <property type="protein sequence ID" value="TXD86808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000923">
        <property type="entry name" value="BlueCu_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028871">
        <property type="entry name" value="BlueCu_1_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033138">
        <property type="entry name" value="Cu_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00127">
        <property type="entry name" value="Copper-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00196">
        <property type="entry name" value="COPPER_BLUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00079">
        <property type="entry name" value="MULTICOPPER_OXIDASE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022658936" evidence="1">
        <location>
            <begin position="31"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="Copper-bind" evidence="2">
        <location>
            <begin position="37"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD86808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="158" mass="17235" checksum="92C654FA44BBE23C" modified="2019-11-13" version="1">MVMKNLKIMSKNSLKMLSMLLLFTSAVAFSQTAKVIEMKGTDQMRFSVETIQASPGQKITVKLSNDSKFPAVAMAHNFVLLKQSADSKAVNLASSKQRDNDYIAPEMKDQIIAHTGLAAGGQTVEVTFNAPKKPGKYTYICTFPGHFQSGMIGTLIVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZBH7</accession>
    <name>A0A5C6ZBH7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_19605</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000044">
        <property type="protein sequence ID" value="TXD86649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="114"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="167" mass="19344" checksum="268403A616710466" modified="2019-11-13" version="1">MKKVCILLFATALMLVGCDNKKKDLTAQSETLMKESDSIEASHQKFEEIHKEMMTEHEKFTERLKGMEVQDSTLLGDLAKHEVILKSHDAIIESHADLIAGHKQLKADFDQLSEVEMEAQLKQIEEDHDRLMKEHATMEEEHEMMMKEHQDIKEIMTEGMETDSDME</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZCF0</accession>
    <name>A0A5C6ZCF0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">AI-2E family transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_17675</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000027">
        <property type="protein sequence ID" value="TXD87264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002549">
        <property type="entry name" value="AI-2E-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21716">
        <property type="entry name" value="PTHR21716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01594">
        <property type="entry name" value="AI-2E_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="63"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="141"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="199"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="226"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="266"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="297"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD87264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="346" mass="38715" checksum="CE3EF2FAA045B5C6" modified="2019-11-13" version="1">MNRQIPPKIIRQIFVLLLILFMGILIIRETIPYLSGVLGAITFYILLRRWMVALVKRYNWKPALAALTLMLASFVVILIPLTGLALMLGNKITKAVNNSEKVVKAFKEQFSRIEDATGIDINSQIDTKSITTWFSQSLQDMAGGTFNVFIAIGLMYFMLYFMLTHRRELRESLREYIPMGIDNLNTIGKEMQVMVKSNAIGIPLVALAQGIIALIGFLIFGIDDPFFWFVIVTIGSVIPFVGTFVGIIPVFLLTLSSGTSFQAWGVLIYGIVVVGSTDNIIRLYVLKKLDDVHPLVTLIGVIVGVPLFGFIGLIFGPLLISLFMVVVKIYKEEYGKSKEQIDKEHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD12</accession>
    <name>A0A5C6ZD12_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_17115</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000025">
        <property type="protein sequence ID" value="TXD87390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD87390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="85" mass="9986" checksum="CBD0E6F4C3EA63F1" modified="2019-11-13" version="1">MRPYITVLKEGEHLREDLVKEIEFLDKEYPKIKIDFVKLDGEFSPEFIEELSKKWNIPVNFMFIGAPGVDCPYRIEELGGVRLII</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD47</accession>
    <name>A0A5C6ZD47_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">IS21 family transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18305</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000030">
        <property type="protein sequence ID" value="TXD87084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Integrase catalytic" evidence="1">
        <location>
            <begin position="135"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="517" mass="60100" checksum="DC364B4BB1C1C7A1" modified="2019-11-13" version="1">MANTLDPMDLKQIITLHLDGYSNRKIGTSLSISRNTVNTYIRLFKGSDYTFKELLSLDTAGLETLFSSHTTITNERYDALMRYFEGMNKARDHPGFTFLYHYDEYARSAKQAYGYTQFMEHYRRKYAKIKGSMKLEHDPGKELFIDYAGKKLHIVDKQTGEVVPVEVFVAILPNSQYTYVEACKSQKREDLIGSCENALRFYGGVPKAIVSDNLKAAVTRSSKYEAQINRSFKDFARHHNCVINPARGYSPQDKALVENAVHLAYQRIYYPLREMTFFSLEDLNLEMKRLLKHYNNLLFKRKEASRLELFQSVEREYLKPLPTTRYELKEYRRAKVQKIGYVYFSPDKNYYSVPYRYIGKETGIHYTKSSVEVYYNHQRIALHPRNPSKGAYTTNKEHLSSTHKFYSDWSPEFFKNKAIPHGSHVAACVGQIIAGVDYPEIGYKRAMGVIQLHRSYGSQRLDNACKRALQADAVSYKRIQNILKNNLDQSSLFFQDLEEDEPHIPEHQNIRGASNYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZD59</accession>
    <name>A0A5C6ZD59_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Aminopeptidase N</fullName>
            <ecNumber evidence="4">3.4.11.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">ESY86_15010</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of an N-terminal amino acid, Xaa-|-Yaa- from a peptide, amide or arylamide. Xaa is preferably Ala, but may be most amino acids including Pro (slow action). When a terminal hydrophobic residue is followed by a prolyl residue, the two may be released as an intact Xaa-Pro dipeptide.</text>
            <dbReference type="EC" id="3.4.11.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.2" evidence="4"/>
    <dbReference type="EMBL" id="VORO01000018">
        <property type="protein sequence ID" value="TXD87977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045357">
        <property type="entry name" value="Aminopeptidase_N-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042097">
        <property type="entry name" value="Aminopeptidase_N-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001930">
        <property type="entry name" value="Peptidase_M1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014782">
        <property type="entry name" value="Peptidase_M1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01433">
        <property type="entry name" value="Peptidase_M1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17900">
        <property type="entry name" value="Peptidase_M1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00756">
        <property type="entry name" value="ALADIPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63737">
        <property type="entry name" value="SSF63737"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="11">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022918419" description="Aminopeptidase N" evidence="11">
        <location>
            <begin position="20"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M1_N" evidence="13">
        <location>
            <begin position="33"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M1" evidence="12">
        <location>
            <begin position="234"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF17900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TXD87977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="671" mass="77308" checksum="577F8B798DFC73FF" modified="2019-11-13" version="1">MKLFFNLTLLIFFFGICSAQQTATVDFKSIKADLSFSKADEAIHGKIAVRFEILEHTDSIFLDAKHLKLKSEVTSENNSIQHKNITTYIGEDKLYLINAFEAGTTYNVVFDYQMQPKKALYFVDDQIWTQGQGKYTSNWLPSIDDVNDKIEFDLSITYENGFEVLANGSLTNKTVEANTTTWHYDMQQPMSSYLLALAIGKYSKKSETSKSGTPLEFYYYPEDASKVEPTYRYSKRMFDFLETEIGLAFPWQNYKQVPVKDFLYSGMENTSLTIFSDSFVVDSIGYTDKNYITVNAHELAHQWFGNYVTATSSEHHWLQEGFATYYALLAEREIFGDEHYYWQLFENAQELIAQEEAGESTSLLDPKSSSATFYKKGAWALHSLREQVGDSVFKLAVKTYLNKHAFANVETEDFITEVEQASGFDLSGFENEWLNTKVLPEDAMVRSLKKSDFMRDYFDINCETYSESCKDYLISTVSDKAKIKIISQMPTHIEAEAFRNSLEVRQAISGYVQDIPKEIKAEYESLLNDKSYVTIENALYNLWVNFPEDRVKYLQKTKDVLGFNDKNVRLLWLALNLNTIEYQPETKQAVLDELIGYSLPKAHFELRMNAFRYLKLLGAFEKQSVTSLMEATKHPVWQFSKFAKTLLAELETNPELKATISDIKNQKTNKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDH3</accession>
    <name>A0A5C6ZDH3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Carbohydrate kinase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_16600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000023">
        <property type="protein sequence ID" value="TXD87513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="1">
        <location>
            <begin position="147"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="324" mass="36449" checksum="6A7A22EED135ACB0" modified="2019-11-13" version="1">MNKGYKIAVVGPIPQDTIITHKNEVITKYGCVSHPTIALAKLLEGKGEVIPISNIHKKDHDAINVLFEPYPAINKSGINSEKDQGTIIELNFIDQNNRLEKQLANMHPITAESVAPFLDADCFVFVPITDFEIELDALKHIKNNSAAKIIFDAHGTTTYVDNEQKRLRKYWKDREDWLPYIDVLKMNLEESLCCWFEKDYSDVHFHDEDRREHLDDFAANVLNQGVTVLYVTLDSKGCAIYSKKEGTIQKDFVASVPVKDVIDTTGCGDSFAGGLAFGLTVYNDPIKAAHYANTLGSRRTQGKGFDVFKSLEETEAIIKAHYHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDI9</accession>
    <name>A0A5C6ZDI9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">YceI family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_17515</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000027">
        <property type="protein sequence ID" value="TXD87233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.128.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007372">
        <property type="entry name" value="Lipid/polyisoprenoid-bd_YceI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036761">
        <property type="entry name" value="TTHA0802/YceI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04264">
        <property type="entry name" value="YceI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00867">
        <property type="entry name" value="YceI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101874">
        <property type="entry name" value="SSF101874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023065516" evidence="1">
        <location>
            <begin position="21"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="YceI" evidence="2">
        <location>
            <begin position="47"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="226" mass="24660" checksum="7741E365B1C89534" modified="2019-11-13" version="1">MKNRPYIRLMLFAVIFTALSCQDKAKKSNTSDAQAAAMSASNHSQFELIIEESKVDWKGFKPTGTHTGTIALEKGDLATDGGKLQSGTIVIDMSSINVTDLEGDDKADLEAHLKGTVAGKKGDFFNTTEFPKAIFEITSTESLAAGKTTLSGNLEMLGQKHNITFPVNITNSEDMMTIESKAFTIDRTQWGINYGSKSVFDNLGDKFINDEIELKFTVKAKKVSAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDL4</accession>
    <name>A0A5C6ZDL4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DUF3298 and DUF4163 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_15240</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021729">
        <property type="entry name" value="DUF3298"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025303">
        <property type="entry name" value="PdaC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037126">
        <property type="entry name" value="PdaC/RsiV-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11738">
        <property type="entry name" value="DUF3298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13739">
        <property type="entry name" value="PdaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022798398" evidence="1">
        <location>
            <begin position="30"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="PdaC" evidence="3">
        <location>
            <begin position="42"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3298" evidence="2">
        <location>
            <begin position="174"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD87827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="251" mass="28461" checksum="578B6E0BC0405762" modified="2019-11-13" version="1">MFNVLQSIPKTVKKLALLVLLPAMILSCAEEVKVNFEEAQIKTTEAANINFNYPKATGTKTVAERINQSIENYVANQTNMANDTLRNVTIDEAVKQFNFEYKRFKSDFPEAAQQWEAFVDGEVTYKSPELICIYINSYLDTGGAHGNTVVRFLNFDAQTGELLEKEALINDRAAFLKIVQQHFQSETKPQDQGETTEDFFFGKDFQLPESIGFNDEGVVILYNTYEIASYAQGITEFLIPYAEVNSLLKQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDM1</accession>
    <name>A0A5C6ZDM1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_18975</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000035">
        <property type="protein sequence ID" value="TXD86895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD86895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="124" mass="13958" checksum="21B2B814252CA319" modified="2019-11-13" version="1">MNLSSNLGKSTLLASAVFWGILGSKVLQITFMPFVLLSFIPIFICVASSVIVSICPIFWLTERESFNKKRIFKAYFPYYAIVVFGICVLAIIDNSFSILAIAFFSSAFISTCQSWVWFAKEEQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-10-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZDW4</accession>
    <name>A0A5C6ZDW4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lysine transporter LysE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_14015</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000016">
        <property type="protein sequence ID" value="TXD88210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01810">
        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="113"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="150"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="189"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD88210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="209" mass="23433" checksum="0D1A7440FF63B416" modified="2019-11-13" version="1">MSITVIFFLGLLIALIGVIPPGLLNMTAAKISLKDGHPSAIVFSLGVCLVVFLQTYIAAMFARYMTNHQDVVEILQRVAFVIFVLITIYFLCVAKGDAQPDVEPHARSKHSRFFQGIFLSAINVFPIPYQAYMTITIASFGWFVFDTTSIVTYCSGATTGTFVMLYMYMFFFDKIKARKLTSQRNMNRMIGAITCIIAIVTFINILMEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE36</accession>
    <name>A0A5C6ZE36_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha</fullName>
            <shortName evidence="10">ACCase subunit alpha</shortName>
            <shortName evidence="10">Acetyl-CoA carboxylase carboxyltransferase subunit alpha</shortName>
            <ecNumber evidence="10">2.1.3.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">accA</name>
        <name evidence="12" type="ORF">ESY86_18715</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>acetyl-CoA + N(6)-carboxybiotinyl-L-lysyl-[protein] = malonyl-CoA + N(6)-biotinyl-L-lysyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:54728"/>
            <dbReference type="Rhea" id="RHEA-COMP:10505"/>
            <dbReference type="Rhea" id="RHEA-COMP:10506"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57384"/>
            <dbReference type="ChEBI" id="CHEBI:83144"/>
            <dbReference type="ChEBI" id="CHEBI:83145"/>
            <dbReference type="EC" id="2.1.3.15"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Lipid metabolism; malonyl-CoA biosynthesis; malonyl-CoA from acetyl-CoA: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Acetyl-CoA carboxylase is a heterohexamer composed of biotin carboxyl carrier protein (AccB), biotin carboxylase (AccC) and two subunits each of ACCase subunit alpha (AccA) and ACCase subunit beta (AccD).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the AccA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.15" evidence="10"/>
    <dbReference type="EMBL" id="VORO01000033">
        <property type="protein sequence ID" value="TXD86961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00655">
        <property type="reaction ID" value="UER00711"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009317">
        <property type="term" value="C:acetyl-CoA carboxylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016743">
        <property type="term" value="F:carboxyl- or carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001295">
        <property type="term" value="P:malonyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00823">
        <property type="entry name" value="AcetylCoA_CT_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001095">
        <property type="entry name" value="Acetyl_CoA_COase_a_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011763">
        <property type="entry name" value="COA_CT_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42853">
        <property type="entry name" value="PTHR42853"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03255">
        <property type="entry name" value="ACCA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01069">
        <property type="entry name" value="ACCCTRFRASEA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00513">
        <property type="entry name" value="accA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50989">
        <property type="entry name" value="COA_CT_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 10" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="6 10" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="12" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CoA carboxyltransferase C-terminal" evidence="11">
        <location>
            <begin position="37"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="TXD86961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="317" mass="35683" checksum="762C37A446014617" modified="2019-11-13" version="1">MEYLDFELPIKELEQQLDKCLIIGEESEVDVTQTCKKIEKKLKETKKEIYKNLSAWQRVQMSRHPNRPYTLDHIKAICGDTFLELHGDRNVKDDKAMIGGLGKIGDQSYMFIGQQKGYNTKARQFRNFGMSNPEGYRKALRLMKSAEKFGIPVVTLIDTPGAYPGLEAEERGQGEAIARNILEMTRLKVPIITIIIGEGASGGALGIGVGDRVLMLENTWYSVISPESCSSILWRSWEYKEQAAEALKLTAPDMKKLKLVDAIIKEPLGGAHTDREATFKAVEKAIVESYEELKNLSQKDLVSQRMDKYLAMGVFKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE55</accession>
    <name>A0A5C6ZE55_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Cyclase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_18505</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000032">
        <property type="protein sequence ID" value="TXD86987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004061">
        <property type="term" value="F:arylformamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007325">
        <property type="entry name" value="KFase/CYL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037175">
        <property type="entry name" value="KFase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31118">
        <property type="entry name" value="PTHR31118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04199">
        <property type="entry name" value="Cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102198">
        <property type="entry name" value="SSF102198"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD86987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="231" mass="26045" checksum="F32009D5687A264F" modified="2019-11-13" version="1">MTEIIDLSQEIYEGMPVYKDLPQVKMTVHNSHEEWNGIKNPETKTPAVHKLELGEHTGTHVDAINHMAIQYKGKSIDKMPLSMFYTEGICLDFSHKKLKELIEPNEIEDACEKTGLKIEKGDTVLIYTDHYRKCFNGKDWSNGPGISTKTARWLGEKEISAFGVETMSPGVPGISNKEVHHICGELNFTHYENMINLNLLIGRGRFRFIGFPLKIKGGTGSPVRAVAIFEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZE87</accession>
    <name>A0A5C6ZE87_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GNAT family N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_16810</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FemABX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000024">
        <property type="protein sequence ID" value="TXD87440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016755">
        <property type="term" value="F:aminoacyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044038">
        <property type="term" value="P:cell wall macromolecule biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038740">
        <property type="entry name" value="BioF2-like_GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003447">
        <property type="entry name" value="FEMABX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13480">
        <property type="entry name" value="Acetyltransf_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51191">
        <property type="entry name" value="FEMABX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Acetyltransf_6" evidence="2">
        <location>
            <begin position="173"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD87440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="356" mass="41017" checksum="A28E9901455DE14E" modified="2019-11-13" version="1">MDFFFTKDKEWLDKWDAYVAVNPRASHLILSDWLKSYLSYGFDYEVGIALEDDIIIGGFGVVIPKVLFFKFYIIPHGPIVTRGYEANLETILGQIRARAKWLNCCYVQVSLPISNNFKIKNHVYSSAEVQNTYHKFKRGKLFDYVYCSYGLNWVDFSNYLKPDDYLESLSPKVRRNIRLPYRKNTQVTYANHIAEIKNGYALIEDNAKEAGYDIRSFDDLKDVILNLIKGHQAFFINIYVDGVIKASAFFIIAAGHLTNIMGGVTKEKPDIKLGYMLQWEAVKRSFELGFIGYNISMGGSQGVKDFKARFGTEAITYENPHFYSVIRPAVFGIFITIEKYIKPYKRKISSLLSKLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZER1</accession>
    <name>A0A5C6ZER1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DUF2723 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_14315</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021280">
        <property type="entry name" value="DUF2723"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11028">
        <property type="entry name" value="DUF2723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="221"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="260"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="291"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="549"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="572"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="603"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="636"/>
            <end position="657"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1109" mass="128407" checksum="B3329B93B71C8E28" modified="2019-11-13" version="1">MTHSNFKKWNTITGWFAFAVALLTFALTIEPTVSFWDAGEYILTSAKLQVGHPPGAPLFQMLGAFFSLFTFGNNSYIGMMLNMMSAVASAFTILFMFWSISILLRKMTKHVGEALTTSTSIAIIGSALVGSLAFTFTDSFWFNAVETEVYAMATLIMAILFYLGLRWEQDMFKPRGHRWLILIAFVIGLSFGVHFMGLLTIPALGLLYFFKNYEKVTAKNFIIANVVAAAILLFIFKLLLPNALLLFSASEIFFVNSVGLPFNSGSIIAGLAIITAFYFGLKYTRDKGYKYANTLTLCLIFIFIGFSSWIMLPIRANADTVINENNPSSARELLAYYNLEQYPETHLFYGPLFTDQYAGLDKNNPYKDAKPKYEKDEEQGKYVIVNDYKNAEQNYNSEHAQILPRMWSGEHAENYMMFTGLLDFKIKPEYQMDNRVRQLVNDFKRDVAQGKLDYADYHSFLKQFGRDFLVIEKPSLGDNLYYMLDYQLGYMYWRYFMWNFTGRQDDIQGKYDDLHGNWISGIDFIDNWHLGMSQDNLPSDVKNNKARNTYYFLPLILGVIGFLFLMSRDPKLFWVMLVFFLFTGLAIQFYTNVRPFEPRERDYSVVGSFYVFAMWIGFGVFAIFNFLRKYANSKFLAPAITIICLALVPGILAANNWDDHDRSDRYTAQAMARMYLESCAPNAILFSIGDNDTFPLWYLQEIEGVRTDVRVVNTSLFQTDWYIDQMKRKAYESDPIPSQLTHAQYQYGTRDYIISQEITKDTFLIKDFIDFISNDDPKYKLKYALEARGEDTSVYPDHLLKSNYMPTTSVRIPVDKQNVLDNNIVKEADADKIVPYIDIKITGSALYKNRLLMLDIIANNDWKRPIYFTGGAFGEDDYIWMKDYLQLDGLVYKLVPIRTPVNRANPFDMGRVDTDLMYKQVMAWDWGNSGSDNIYHDVETRKNGITYRGNLARLMEALINEDRLEKAEDIADLAMENLPVDKFGFYTLLEPYISGYYEVGNKEKARKLYREVSKKYQESLTYWSGLSIKNQTRYLDEIVTDIERYRSLVDLLVLYQDESFAMEETEKFNNYLKLFKHFTEGDKEDVEPVIDERDLQKDSTNADTLFKIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF38</accession>
    <name>A0A5C6ZF38_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ESY86_13110</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000014">
        <property type="protein sequence ID" value="TXD88447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055072">
        <property type="term" value="P:iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030287">
        <property type="entry name" value="FbpC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24220:SF675">
        <property type="entry name" value="PTHR24220:SF675"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 8 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0410">Iron transport</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="2"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="TXD88447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="303" mass="34562" checksum="206B81407D686D46" modified="2019-11-13" version="1">MLKVHQLSFSYNTTSVLEQLNFEVRQGEHVSVIGESGSGKSTLLKLLHGEYDLDQGEIFWKDEQILGPKYNLVVGYEFMKYVAQEFDLMPFTSVAENVGKFLSNFYPEEKKERIAELLEVVELTDFANTKVKTLSGGQKQRVALARAIAKQPEIILLDEPFSHIDNFQKQSLRRKVFKYLKDKNITCIVATHDRDDVLGFSDRMLVLNNTKIAANAAPKALYKNPETALVAAFFREFNSIDQNIVYAHQLQVVENSDLKAKVIHSYFKGAYYLIEAETEQQQLFFEHPEPIPTGTDVSLVIKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-02-10" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZF81</accession>
    <name>A0A5C6ZF81_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PIN domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_15440</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000019">
        <property type="protein sequence ID" value="TXD87862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09873">
        <property type="entry name" value="PIN_Pae0151-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044153">
        <property type="entry name" value="PIN_Pae0151-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10130">
        <property type="entry name" value="PIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00670">
        <property type="entry name" value="PINc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PINc" evidence="1">
        <location>
            <begin position="1"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD87862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="146" mass="16645" checksum="8CE9EA994A0B91DC" modified="2019-11-13" version="1">MKIVIDTNIIFSGLLSPNGTISDLLLNSSNTFDFYSPTYLLDELENHKKKLLKISGLSEKELGFLQRHLSKKIDLIDLESIRESTWETAIELTNHVDEFDAPFIALALELDSPLWTGDKKLIKGLNKKGIDWILTTEIITEIRNEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZFW9</accession>
    <name>A0A5C6ZFW9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">VanZ family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_14470</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006976">
        <property type="entry name" value="VanZ-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04892">
        <property type="entry name" value="VanZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="VanZ" evidence="2">
        <location>
            <begin position="45"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="130" mass="14531" checksum="149B11202488E154" modified="2019-11-13" version="1">MLTKILLALKKWALPLLVLYAFALTAGSLVNTGGMPDLGSSFDDKIYHAVAYSIFTILIYNVLKLKNFESRIFIAVVAVLVYGIIIEVLQYLLTTYRTLDGYDILANSIGAILGMLLLWMRKEVKLKKNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGE2</accession>
    <name>A0A5C6ZGE2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_10320</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="300" mass="34084" checksum="C1CB9CAF82A94DDA" modified="2019-11-13" version="1">MAANELIVPADFADGRRKRIALYLSGKTKTFTGICKGAITTAKRGKDGSLQLYLSHYANLISSKSELFFESYSVEILTNYSNNPKGQISSISKTNSKGQTEQKDVRYAHEQYSYVRDKNMLLDTYETKIKIDNEIIGIERNIWVNSGGKIYVNKKLAGPSTNQLLVNGETTYVDNFGNSLELNNGKNVFSSSLRAYANLYEVASVVNAKYIDVVNELDITYAQLQNLNTSVLKLELMKLYNRLPNAMLSLTFYDDSGRVINRVNERQEESYIYYDNHGRVDYITDGYGKVLEKKEYNFNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGW2</accession>
    <name>A0A5C6ZGW2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_14555</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000017">
        <property type="protein sequence ID" value="TXD88103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD88103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="233" mass="25883" checksum="CA1FA86CFB512CB0" modified="2019-11-13" version="1">MISIKDLHKSYHMGKNSVHVLKGINFDVKEGEMVSIMGSSGSGKSTLLNILGMLDEADEGSYTLDNVPIKNLNEKIAAKYRNEFLGFIFQSFNLINYKSALDNVALPLYYKGMNRKERTERSMHYLEKVGLAQWSHHLPSELSGGQKQRVAIARALVSDPKVLLADEPTGALDTQTSYEVMELIQGINDAGKTILVVTHEHDIAQMTKRIVNLKDGVIIDDSVVEQVRASAHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZGW8</accession>
    <name>A0A5C6ZGW8_9FLAO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">ATP phosphoribosyltransferase</fullName>
            <shortName evidence="11">ATP-PRT</shortName>
            <shortName evidence="11">ATP-PRTase</shortName>
            <ecNumber evidence="4 11">2.4.2.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">hisG</name>
        <name evidence="14" type="ORF">ESY86_10440</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">2-80-2</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 11">Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + ATP</text>
            <dbReference type="Rhea" id="RHEA:18473"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:73183"/>
            <dbReference type="EC" id="2.4.2.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="11">Feedback inhibited by histidine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the ATP phosphoribosyltransferase family. Long subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.17" evidence="4 11"/>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00006"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003879">
        <property type="term" value="F:ATP phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00079">
        <property type="entry name" value="HisG_Long"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013820">
        <property type="entry name" value="ATP_PRibTrfase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018198">
        <property type="entry name" value="ATP_PRibTrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001348">
        <property type="entry name" value="ATP_PRibTrfase_HisG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020621">
        <property type="entry name" value="ATP_PRibTrfase_HisG_long"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013115">
        <property type="entry name" value="HisG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21403">
        <property type="entry name" value="PTHR21403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01634">
        <property type="entry name" value="HisG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08029">
        <property type="entry name" value="HisG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="SSF54913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00070">
        <property type="entry name" value="hisG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03455">
        <property type="entry name" value="HisG_C-term"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01316">
        <property type="entry name" value="ATP_P_PHORIBOSYLTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11 14" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 11" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HisG" evidence="12">
        <location>
            <begin position="51"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="HisG_C" evidence="13">
        <location>
            <begin position="211"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="TXD88908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="285" mass="31001" checksum="0053AB125E874153" modified="2019-11-13" version="1">MTKLRIAVQKSGRLHDDSMKILNEIGISIDNGKDQLKASAKNFPLEVFYLRNGDIPQYLIDGVVDAAIIGENVLIEKGGAISIVEKLGFSSCKVSIAVPKSAKYSGVQDLEGKRIATSYPNTVKQFLEKHNINAHLHIINGSVEIAPNIGLADAIVDIVSSGSTLFKNGLKEVEVLLKSEAVLAVSPMISAKNKATLDKLQFRLQSVLLGRQSKYVLLNAPNEKLEEIMAILPGMNSPTILPLAREGWSSLHSVINKNDFWEVIDGLKKHGAEGILVCPIENMVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH21</accession>
    <name>A0A5C6ZH21_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Peptidoglycan DD-metalloendopeptidase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_08615</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045834">
        <property type="entry name" value="Csd3_N2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19425">
        <property type="entry name" value="Csd3_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Csd3_N2" evidence="6">
        <location>
            <begin position="150"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M23" evidence="5">
        <location>
            <begin position="287"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF19425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD89435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="436" mass="50014" checksum="4AF59C609C910DA2" modified="2019-11-13" version="1">MKYNTMKFNKALIALLICLGFLSCKEDTKKLDLEPIAEVIEPEPITEFGFVLDEYIVKRDTIKAGDSFGKILQRNNISYPKIYQIAEKAKDSFDIRKLQTGKPYTLLCAKDSLQTPRCFIYQPSLSEYVVVNFQDSIHAYTSRKPITYIEKTATGVIESSISETLQEKGLSPRLAFKLADEIYAWTIDFRRLQKGDRFKVIYTDKYINDTTYVGLHNIKAAYFEHNGEPFYAFEFETDSIKGIRDYFNEDAKNLRRAFLKAPVQFSRISSRYNLNRRIAYYGYKLRPHKGTDFAAPLGTPIMATANGTVTESTRRGGNGKYVKIRHNATYSTQYLHMKAQNVKKGQYVKQGDVIGWIGMTGNSGGPHVCYRFWKNDKQVDPLREKLPEAEPISASLKLKYLDYIAPIKTRLDVIPMDEELKDQIAQSSNDINLQTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-08-12" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZH65</accession>
    <name>A0A5C6ZH65_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NUDIX domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_12005</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000012">
        <property type="protein sequence ID" value="TXD88683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004385">
        <property type="entry name" value="NDP_pyrophosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00052">
        <property type="entry name" value="TIGR00052"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="2">
        <location>
            <begin position="42"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD88683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="194" mass="22103" checksum="5843F4704EF235E1" modified="2019-11-13" version="1">MNKIKNITHTTLSKQWGTLNRIDYDYQFENGAWKRLSRESYNRGDGAAILLYNVENSTVILTKQFRMPIYENHREEGMSIEVCAGAIDHKDSPLETIIRETEEEVGYKIKNAKQVLTAYTSPGALTEKMFLFVAEYKQELKVDEGGGLASENEDIEVLELSFSKVLEMVENGDIVDAKTIMLLQYAQINTLLHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHD1</accession>
    <name>A0A5C6ZHD1_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidoglycan-binding protein LysM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_11070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000011">
        <property type="protein sequence ID" value="TXD88775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="223" mass="24911" checksum="AB825ADB78972DE4" modified="2019-11-13" version="1">MINKVSHYFAIPLAIFSLLFMALKPGPKLDMSLYSTEGMEFDYTTSHELAMNTESNELAAPFHEHHAYFPYLGKSYNGFKEALAFKESRGNYFSVNTLGYLGKYQFGSETLKLIGIYNPNQFLYNPKLQEKAFLANAARNKWILRKDIKRSVGKTIGGVKITESGILAAAHLAGAGTVKKYLRSSGSYNFSDAYGTTVGHYMKKFAGYDTSFIVANKKAKARI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHE8</accession>
    <name>A0A5C6ZHE8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Alpha/beta hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_10230</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000801">
        <property type="entry name" value="Esterase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00756">
        <property type="entry name" value="Esterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="255" mass="29334" checksum="6BCFB00BB988DAC9" modified="2019-11-13" version="1">MTVMEFDPIIEVLEEAYEIPQLNATRKISALLPYDYHYTDKRYPVLYLQDGQNLFNPQAPYGDWAIDKSMAKLAEEGLSDMIIIAIDHGEEERVNEYLPYYHPRFGQGKGNFYIEFMVERLIPYVNKNFRTLPNFENTGIGGSSMGGLISLHAGLSNPGVFGKMMIFSPSLWISKTIFNNTKSFTPLQKSKIYLYAGAKESLEHLPNAQKLSGIIKEKMVKGHHIDFHFSINDLGNHAEVHWREEFPKAVKWLYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHS4</accession>
    <name>A0A5C6ZHS4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DNA polymerase III subunit delta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_08040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000006">
        <property type="protein sequence ID" value="TXD89722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="384" mass="44071" checksum="3F92E98B9C609A89" modified="2019-11-13" version="1">MLFSEILGQEHIKKHLTTSADFGRVPHAQLFVGPEGSGTLPMAIAYAQYLLCKNTNSENSQGKEACNMKFKNLSHPDLHFAFPVATTEAVKKHPVSKLFMQEWRQLIEKQPYGNLFDWYRTLGIENKQGQIGVDEAQEIVKSLSLKAYEGGFKLMIVWMAEKMNTAASNKLLKLIEEPPDKTIFILIAEDEEQIINTIKSRCQLLRFPRLAEQVIKEALVKNFQLKEADALKIALQSNGNYNKACDLVYSDSEDTQFEEWFVYWIRAAFKAKGNKSAIHDLMSWSETLARTGRETQKQFLNFCLDYFRQALLLNYKADDLVFMQPQTEFKLEKFAPFVHGNNIMEISSELQDAIYHIERNGNSKIILTDLSIKLTRLLHQKADS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHT0</accession>
    <name>A0A5C6ZHT0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alkene reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10815</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045247">
        <property type="entry name" value="Oye-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22893">
        <property type="entry name" value="PTHR22893"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidored_FMN" evidence="1">
        <location>
            <begin position="12"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="367" mass="41218" checksum="8CD702D177DE64E6" modified="2019-11-13" version="1">MSKQPLLTPYHKNIDLKNRVVMAPMTRSRADNDGHVATDELQGLYYEQRASAGLIITEGSQVSKDAVGYINVPGIITPEQVEGWKKVTKRVHDKGGKIFIQLWHVGRISHPDFHDGDLPLAPSAINPNAKSFTPEGNKDTVTPKAMTKEDIKQTVKDFQNAAKNAVEAGFDGVEIHSSNGYLFHQFFSGTSNIRTDEYGGSHENKARIFFEVLDAIKEVIPQEKIGARFNPSLNGIFGMTMDEDSIPTFDYIIKRLNDYNLAYIHLSEPFNDVSDIDFAVQHIAKHFRPLYNGTLMINANFDQESGNKIIESGDADLVAYGKLYISNPDLVERFEHHLEMADWDEDTFYVPGKKGYTDYPKASKENA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZHU9</accession>
    <name>A0A5C6ZHU9_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10925</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="98" mass="11044" checksum="6B585FD91D803D26" modified="2019-11-13" version="1">MSNEKKDKKQETYNPEITKEDKKALGDKAGNLHTDLSDDELLKEREEAVDFAGSDLDVPGRDLPKNTNHKSLKDEENQMYSQGGPGNEDLENTTEHVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI16</accession>
    <name>A0A5C6ZI16_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycosyltransferase family 2 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ESY86_09970</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="384"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="412"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="445"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="3">
        <location>
            <begin position="125"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="TXD89089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="481" mass="54998" checksum="080937BEADC7B7C7" modified="2019-11-13" version="1">MNNDISPSNESSHTNHSSQTSKPKSLKSFFQKNKASNKITTPWGITVLLCTFLLMVGSLFLVFSLQSDFEQFNLERLNSVWGYSFMAVATGLFAYKALFFMYMFYKYFKYKAVDSVSDEKLPTCTIIVPAYNESRQVYDTLVSLAKSDYPKDKIQILSIDDGSLDDTWTWMLEAKKRLGDRLQIMQQAKNQGKRHALYRGFNMGTGEIFVTVDSDSIVKPDTLRNLVSPFVDNEDCGAVAGNIRVLNNKKALLPRMLDVSFVLSFEFVRSAESALKSVLCTPGALAAYRSTAVYKCLPEWINQTFMGQASDIGEDRAMTNMILKQGKHVLFQRNAVAYTNVPEQYRGLYKMFIRWGRSNVRENLEMSKYVFTNFREGSKLGTRLLFIGQFSKIVMSYPFMVFMLFFVLMHPILFITSTLVSILILSTFSVVFYSKHYEISEAFWAYSYSILYTFGLFWITPYAIATASRSGWLTRGLAEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZI33</accession>
    <name>A0A5C6ZI33_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">FAD-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_10875</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000010">
        <property type="protein sequence ID" value="TXD88986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amino_oxidase" evidence="1">
        <location>
            <begin position="15"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD88986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="425" mass="47459" checksum="F02F7A53B4DE559C" modified="2019-11-13" version="1">MDRKDYKIHIIGAGISGLLAAKTLENQGYRPTIIEATDRIGGRVKTDIVDGYQLDHGFQVLLDAYPMAKKHLDYDALELQKLIPGAVIFKDGSSNTIGDPLRDLSLLWSTMTASVGSFSDKLKILKLNVKLKGRSLETIFAAEERSTREYLQAEGFSERIISNFFKPFFAGIFLEPDLKTSSRMFEFVYKLFGEGMAVLPKAGISAITEQLKSQLNDTQFKFNTKVSAVNDEHILLDNNQKLQTHFTIIATEASSLLSNLNTKTQWKSCDNLYFTVKSKTIQKPIIGLVADADALINNLFYCNSVATKSKGAQELLSVTVVKKHELNEKDLIMKVQEDLKQFCDIEHSTFLKRYQILQALPDLEHLHYDCSPTETRIKPTIFLAGDQMLNGSLNAAMIAGERAAQGVILALEDGLRADGITSEYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIB6</accession>
    <name>A0A5C6ZIB6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cell envelope biogenesis protein OmpA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_08690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000007">
        <property type="protein sequence ID" value="TXD89449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011250">
        <property type="entry name" value="OMP/PagP_b-brl"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56925">
        <property type="entry name" value="SSF56925"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022935528" evidence="1">
        <location>
            <begin position="24"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD89449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="209" mass="22811" checksum="F6241E2BC2EA8EAA" modified="2019-11-13" version="1">MTPNYRPLIFAVVCALITTLSFAQRPTNEWKAQLALGVNNASSSGFVAGFESKSLNFPTVNLGIQHMFKKQLGAKLDFGFNRFSSGEASLEFKTNYTRINAQLVYDPTEALVFLPQRIGIVAHAGPGYSIIKPLGNYSNNDLSFLNAMAGVEFHYGLSQTLSVYTDVSYIMGFANDFDPVAEGFGAFNGDLLTVTFGLTFSLSGCRYCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIG5</accession>
    <name>A0A5C6ZIG5_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_09595</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="136" mass="15961" checksum="DFE205393A254D2C" modified="2019-11-13" version="1">MKTLLNLIWLFPFFIINNNFVCKNIKLDPLHYQSNQDQQKKLSATIAHEYDRYVSPVKITYQVYPYGGSKKYEYRWRLKGQKYGNYSNNTTYTLIFDCSINERPVSTIFCQVKDIVSGEIISVMTTHPVEICTVKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIG6</accession>
    <name>A0A5C6ZIG6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF2911 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_12140</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000013">
        <property type="protein sequence ID" value="TXD88489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021314">
        <property type="entry name" value="DUF2911"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11138">
        <property type="entry name" value="DUF2911"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD88489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="193" mass="22315" checksum="82BD845321B89806" modified="2019-11-13" version="1">MNTFLKRLLIFLFVVALGLFLYSTFVEDLFGNRLSPEDTVEFKLNDLKLAVFYNRPSKKGRDIFGGLVPYNKVWRTGANEATTFETNKNLMVDGILVPAGKYTLWTVPKDSVWNVIFNTKQYPWGVDAEMQPMWDPNYDIMEIDVPVEKLNNAVEQFTIAFDNSTDNLELTMAWDHTKIAVPLEVMKEEEEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-06-02" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIL7</accession>
    <name>A0A5C6ZIL7_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">O-antigen translocase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ESY86_10140</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009246">
        <property type="term" value="P:enterobacterial common antigen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13125">
        <property type="entry name" value="MATE_like_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002797">
        <property type="entry name" value="Polysacc_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044550">
        <property type="entry name" value="WzxE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01943">
        <property type="entry name" value="Polysacc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="74"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="112"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="171"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="259"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="296"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="354"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="388"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="TXD89161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="417" mass="47490" checksum="C1E6498A8B12DE6C" modified="2019-11-13" version="1">MTSFNAVVIVIRLVISFFIMRFLAVTLGEAGIAKIGSLRNVVQILTSTSSLGTFNGIVKYVSENEQDQNRISKLFSAVFIFGVIGSVLSGAILFFSATYLSVNLFGDDSYVTLIRCLAFLPPIIGLNRIFYGVINGLSDYKKYAKIELVSYLFSAALLLIFLYSFSLKGVLFSIILTPILSFAVILMFFYKRLRSYIHLNELSFDLSFAKPLLAFTLMSFISSVLINYIELDIRTTITNRINISEAGYWTAINYLSKNYMVFSSSIFTLYVIPKFAKIHTGVAFKKEVFHIYKTILPLFGLGMLLVYLFRNVIIQLVFPGFDGLEPLFKWQLLGDFVRLATLVISYQFLAKKMVWSFVVTELISLGLFYGLSKYLVDIYGAEGVVMAHFYRYAIYFFIVIFAVWNYFKNQDKKQKDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIM8</accession>
    <name>A0A5C6ZIM8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GNAT family N-acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_09000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="9"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="CN hydrolase" evidence="1">
        <location>
            <begin position="225"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="510" mass="58656" checksum="F70C63AC66B576DA" modified="2019-11-13" version="1">MEEQKIENIELEYLNVDDFKELKAATLQSYDGMLNSFWEKHHVERLTTIFPKGQVVIKIDGNIAGCALSLIVDSAMLEDDHTYADIADDDKFKAHTSRGDTLYGIDVFIRPEFRGLRLGRRLYDYRKELCEELNLKSIVFGGRMPNYHKFKNELTPKQYIEKVKRKEIHDPVLNFQISNDFHPVRIIKGYLEGDTQSNEYAVLMEWDNIYYTKKNKKATTVKTVVRLGLIQWQMRSYSGLEDLMEQVEYFVDSVSAYRSDFALLPEFFNAPLMAKYNHLHEPEAIRELAKYTAVIIEKLQQLSISYNINIISGSMPELVGDKLLNVGYLCRRDGSLERYEKIHVTPDEEKVWGMQNGSKLQTFDTDCGRIGILICYDSEFPELSRLLADEGMDILFVPFLTDTQNGYSRVRICAQARAIENECYVAIAGSVGNLPNVNNMDIQYAQSAVFTPCDFSFPNNGIKAEATTNTEMILVADVDLSLLRELHNFGAVKNLKDRRKDFYNVIRVSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZIY0</accession>
    <name>A0A5C6ZIY0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cell division protein FtsW</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ESY86_09385</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">2-80-2</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000008">
        <property type="protein sequence ID" value="TXD89246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001182">
        <property type="entry name" value="FtsW/RodA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30474">
        <property type="entry name" value="PTHR30474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01098">
        <property type="entry name" value="FTSW_RODA_SPOVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0133">Cell shape</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="45"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="73"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="107"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="143"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="170"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="194"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="276"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="314"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="351"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="TXD89246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="399" mass="43795" checksum="90F0B39E80F723C5" modified="2019-11-13" version="1">MGQIFRNIKGDRLIWAIAALLAIFSFLPVYSAASNLAYVGGSDNTFTFFVKHFMHLFLGFAIIYGVHKVPYRYFRGLSMIMVPIVLVLLVVTMLQGTTIDGANASRWIQIPFVGMSFQTSTLAAVVLMVYVARYLSKIQDREVTFTETLLPLWAPVFFTLILILPANFSTTAIMFLMVMILAFIGGYPLRYLAVIIGIGILSLALFVLVAKAFPGAIDNRIDTWMSRIENFSNGVDTEADYQIEKAKIAIASGDIFGRGPGKSQQKNFLPQSSSDFIFAIIIEEYGLVGGLILLAMYCWLLFRIVIVSQKSDTVFGKLLVLGVGLPIVFQALINMAVAVELFPVTGQTLPLISSGGTSIWMTCLAIGIVLSVSAKREADKDKEAESFDDNPLAVLSEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZJ86</accession>
    <name>A0A5C6ZJ86_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_10075</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000009">
        <property type="protein sequence ID" value="TXD89107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD89107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="170" mass="20007" checksum="3E25984E92C7BF28" modified="2019-11-13" version="1">MRPFEKWENLPIFKKAMQLSDLVDHITEAVDKTDIDFERAIEAEMIKSNLSYMRQNAMTIPAKIAGAASEDMLYDIRMENAAIIRKAARELITDARGIEMHGFKDIEYLDLLRQEVEEFRILFAEWVKTFDQWHYIIDRWGLFNPPGINYDDHDPDDDIPFNPDDFFDGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKI0</accession>
    <name>A0A5C6ZKI0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Phospho-sugar mutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">ESY86_03155</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016868">
        <property type="term" value="F:intramolecular transferase activity, phosphotransferases"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016066">
        <property type="entry name" value="A-D-PHexomutase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005841">
        <property type="entry name" value="Alpha-D-phosphohexomutase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00509">
        <property type="entry name" value="PGMPMM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="SSF53738"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="SSF55957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00710">
        <property type="entry name" value="PGM_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM_PMM_I" evidence="8">
        <location>
            <begin position="48"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_II" evidence="9">
        <location>
            <begin position="209"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_III" evidence="10">
        <location>
            <begin position="323"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_IV" evidence="7">
        <location>
            <begin position="481"/>
            <end position="543"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="TXD90379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="576" mass="64186" checksum="C7B866178DC87F0D" modified="2019-11-13" version="1">MTNTAQHLLDRINPWLTSTFDEDTKNRIKYLRANNPKELEESFYKNLDFGTGGMRGIMGVGTNRINKYTLGKNTQGLSNYLHEQFPAEELKVAIAYDCRHNSKTLAQVVADVFSANGIKVYLFEDLRATPELSFTVKYLNCQCGIVLTASHNPPEYNGYKVYWQDGGQLVPPHDSKIVDEINSLDYSEIKFEANKDLIEYIGKNVDDVFIDKCVENGSFNTSNNAKQDLNVVFTSLHGTSITVVPETLKRAGYTNVHLVEQQKVPNGDFPTVISPNPEEPEALKMAMELAAQVNGDIVIGTDPDCDRLGVVVRNLTNELVILNGNQTMLLMTDFLLKQWQKQGKINGKQFVGTTIVSTPMMPVLAEAYNVECKIGLTGFKWIAKMINDFHELDFIGGGEESFGFMVGDFVRDKDAVTSTLLACEIAAQAKAEGKTMYQKLIELYVTHGFYKERLVAITKKGQEGAQEIKQMMIDARENPLQSVNGSKVVKIEDYELSVEKNLISGKEIKLDIPKSNVLIYTTADGSKIALRPSGTEPKIKFYISVNAALDSAENYNNVDAELGSRIDGILKDMKLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKM0</accession>
    <name>A0A5C6ZKM0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Mechanosensitive ion channel family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ESY86_05195</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="13"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="60"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="TXD90145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="353" mass="39977" checksum="A073738630F3CDD8" modified="2019-11-13" version="1">MDTIFSKLSITDLWLKIVITFAVCILVGLVLQLVVFYLLKTYNKKKPTVLKTQLLKHLETPVKLLLPILFIYSSFGLFSISKVWHTVIEVIIIVNFTWVLLAIIRAVEEIVKQKFTTNSSHKAKERKAITQMRFIKSASIVVIVTLATATILWNIPAVRTIGTTILTSAGVIGIIAGVAAQKSIANLITGMQIAFTQPIKIDDEVVIEGEFGTVEDITLTYVVIKTWDWRRLVLPLNYFNDHHFINRSFNSPELIGTVYLYVDYTFPVAELRKKCLDIIGENILWDKKVAQLLVTNADAVSVEVRVTFSAKNAASVWDLSCQIREQLITFIQEQFPESLPKIRREPPISQKET</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2021-09-29" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKX0</accession>
    <name>A0A5C6ZKX0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">CocE/NonD family hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_06330</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000005">
        <property type="protein sequence ID" value="TXD89818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008239">
        <property type="term" value="F:dipeptidyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005674">
        <property type="entry name" value="CocE/Ser_esterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000383">
        <property type="entry name" value="Xaa-Pro-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013736">
        <property type="entry name" value="Xaa-Pro_dipept_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02129">
        <property type="entry name" value="Peptidase_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08530">
        <property type="entry name" value="PepX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00939">
        <property type="entry name" value="PepX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00976">
        <property type="entry name" value="NonD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5023114913" evidence="1">
        <location>
            <begin position="21"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="domain" description="PepX_C" evidence="2">
        <location>
            <begin position="359"/>
            <end position="614"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD89818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="619" mass="71316" checksum="6CCCFCDA46B6967E" modified="2019-11-13" version="1">MKFIQCLVVAFLVTTSSVFSQETLSKSTQTYQVEDHYNKQEVMIEMRDGIHLHTSIYTPKDKAQSYPMLMMRTPYSSQPYGETTFRKKIGPNEYLMKEGNIMVYQDVRGRWNSEGVYDNMRAYIPNKTGNEVDEASDTYDTIEWLINNVENNNGNVGTWGISYPGFYATYSLLSGHPALKAASPQACIADFFFDDFIHNGAFLLSYWRATSVFGYMKDQPTKEAWYKFPEIGTEDQYQFFLDAGPLSNLDQYYGDENVFWNQIQAHPNYDEFWQSRGIIQHLKNIKPATLIVGGLFDAEDLYGPFTTYKTIEENSTNENTVVFGPWSHGDWARGSDRQVIGNIDFGDGLSDYFQKEIETKFFNKYLKGVETSALPEARMFNTGTKEWESFDSWPPKNVKKQTYFMQPYEQLTQQANRMFATSDFVSDPKKPVPYSEAIKVVFTPRKFMTDDQRFAARRPDVLVFETEVLEKDITLAGAILTTLNVSTTGTAADWVVKVIDVFPADTKNTSDVQDHLKLSNYHMMLRSEVIRGRFRNSMSQPEPFVPNQKTAVPLKLQDVFHTFKKGHKIQVQVQSTMFPYIDVNPQTYVDNIFEATEADFKKQTHKVYNDSAIEFMVLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZKX8</accession>
    <name>A0A5C6ZKX8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_03690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="91" mass="10847" checksum="E3F4B629C590AEE7" modified="2019-11-13" version="1">MSGKYKFHKPVVAYFTSFIYRFFILFDIKKRKSSQHNNANIYLRITSVGQRAEFNLRRKEYKFMEFKFLPFLAGLAKWKSEALVSAPRPLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLC2</accession>
    <name>A0A5C6ZLC2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_02390</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="191" mass="21770" checksum="79EEF50D76F19717" modified="2019-11-13" version="1">MLLQFNGFHGTSVSAAKQIVSSNYETSIGDDEWLGNGVYFFVSGISSKPEEQAKKWAIAEAWDKDKQVYKYKNYCVINSVIEVEEDNFIDLTKEEGVEILTYLAECFEKKLNKISKRFKAVDGLLINLAREEGILPIDVVKGNFYIKFAKERIKRITLRTSNCTICTVYEPTKNITNSNIIEIGDIKDETK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLD0</accession>
    <name>A0A5C6ZLD0_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_05555</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000004">
        <property type="protein sequence ID" value="TXD90207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="66" mass="7773" checksum="F1609A0878157FC7" modified="2019-11-13" version="1">MGYGGQVIILIPDKELIIVTTHNHDTPIGIEQQIKFLKEKLPKTLRRICEFIKYNNIQNPMIFLMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLG2</accession>
    <name>A0A5C6ZLG2_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Four helix bundle protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_03780</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000003">
        <property type="protein sequence ID" value="TXD90495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd16377">
        <property type="entry name" value="23S_rRNA_IVP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012657">
        <property type="entry name" value="23S_rRNA-intervening_sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036583">
        <property type="entry name" value="23S_rRNA_IVS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38471">
        <property type="entry name" value="PTHR38471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05635">
        <property type="entry name" value="23S_rRNA_IVP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158446">
        <property type="entry name" value="SSF158446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02436">
        <property type="entry name" value="TIGR02436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="121" mass="13859" checksum="F2B06CEBDAAEA871" modified="2019-11-13" version="1">MAARHNFRKLSIWKDGIGIVKETYAITKTFPRSEDYALSSQMQRCSVSIPSNIAEGTSKGTDKHFIQYLETALGSAFEWETQLIISFEIGYISEETFKHLENKIQIIQGMITRFMENLSKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLQ4</accession>
    <name>A0A5C6ZLQ4_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GLPGLI family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_02320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005901">
        <property type="entry name" value="GLPGLI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09697">
        <property type="entry name" value="Porph_ging"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01200">
        <property type="entry name" value="GLPGLI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5022775959" evidence="1">
        <location>
            <begin position="26"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD90815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="285" mass="31905" checksum="09B7264FAD259D28" modified="2019-11-13" version="1">MKPVNFTFKCLLSLALMTLSPIAGNAQGAKDFQGQATYISKSSLDLGDWGARLSEEQKKQVKAQLKNRLEKTYTLTFNKTESFFKENDKLDAISGATDSWGKNFAAGDQYKNVKTNAQIQEQEFYGKRFLVKDSLQPISWKLGSETKQIGDYTCFKATASIPTNELTWYSFSWDKLRQNSSATAEGTQETASEETLQLTEVEAWYSPQIPVGHGPSEYWGLPGLILEVSAGDTTMLCSKLVLNPAERLEIKAPEKGKDITKTQYQATIVEKMKEFRSNRTGRSRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZLX8</accession>
    <name>A0A5C6ZLX8_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">SHOCT domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ESY86_02760</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018649">
        <property type="entry name" value="SHOCT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09851">
        <property type="entry name" value="SHOCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="domain" description="SHOCT" evidence="2">
        <location>
            <begin position="34"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="TXD90895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="63" mass="7752" checksum="F3E7561DEE353CE5" modified="2019-11-13" version="1">MMMWWWILIPVLLVLGAVLYIRRNKENIRYRENPMAILDKRFAKGEINKEEFEEQKRTLNTKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMH3</accession>
    <name>A0A5C6ZMH3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">PAS domain S-box protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ESY86_01375</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">2-80-2</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="5">
        <location>
            <begin position="26"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="6">
        <location>
            <begin position="156"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="7">
        <location>
            <begin position="229"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="6">
        <location>
            <begin position="282"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="7">
        <location>
            <begin position="353"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="6">
        <location>
            <begin position="401"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="7">
        <location>
            <begin position="473"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="7">
        <location>
            <begin position="603"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="6">
        <location>
            <begin position="787"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="7">
        <location>
            <begin position="859"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="6">
        <location>
            <begin position="1032"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="7">
        <location>
            <begin position="1104"/>
            <end position="1156"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="6">
        <location>
            <begin position="1198"/>
            <end position="1243"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="7">
        <location>
            <begin position="1246"/>
            <end position="1298"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="7">
        <location>
            <begin position="1373"/>
            <end position="1425"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="1443"/>
            <end position="1655"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="3">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="TXD91266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="1655" mass="188286" checksum="2839D49C8B059906" modified="2019-11-13" version="1">MVFIGCSRIKLRFKQLKPPKLKTKLKILHLEDTPTDAELVERELKKGNIQFETLVVANKTAFEQALKAFAPDIIISDHTLPSFDSLEAIKMIKRQGLKIPIILVTATVSDEHAVEIMKAGADDYILKDRLHRLPQAVLNAMEKFSMEQERERMIYDQAHLAAIVNASNDGIISKTLDGIITSWNTGAEELLGYSAAETIGKNIAIIIPPDCLPVEAEFMESLKRGESVQHFETVRLTKNGVRVDVSLTISPIKDHNGKVIGAAKIVYDITDRKKAEQIIYDSEEKYHSLFENSLDAILLTVTDGKILAANPAACTMFGMSEKEICEAGRFGLVDTKDPRLAAALEERQRTGAVKAEVTTIRKNGETFPGEFTSVVYKNANGEERTSMIVRDLSERKRAEEEITKLSLVARKTSNAVVITDAKGEIQWVNDAFTRMTEFELNEIIGEKPGSFLQGPETDPVVVDYMHNKILNRQAFNCEIINYTKTGNKYWTRIQCQPEFESTGKLDGFFSIQTDITKEKEAEQAIAKLNERMALATTSVKMGIWEWDVVNNHFIWDKIMYQIFGVAEDEFCSANEAWEAMIHPDDIVEENEKVQIALSGDAKFDSEFRIVWPDKSIRYIKGDAIVEKDDNGKPLRMIGTNFDVTERKSLEKAVETERDQFFEMFSKAPSAIGMLKGPNHVFEMANPLYLHLTGKKDIVGKTVAEVLPEVIEQGFVSMLDHVYQTGESYTGNEMLVKVDTEGNGVMTDFYIDFVYQAYKNGKGDIEGVFFFINDITEQILSRKETEKSEKQYRQIVETAQEGIWLIDEHSRTTFVNKKMCEILEYTEEELIGKEHSFYMDADGKEKAVLALERRKRGISENLEFNFISKHGKHVLTKVSANPIFDDLGNFKGSLGMVSDITEKKHLEDLLEKSNRLAAVGSWEIDVVTETVYWSDITKEIREVDKDYVPLLGEGISYFKEGIHRVTIEQKVKDCIKHGTPWDEELQIITFKGNEKWVRTIGQADFLDGKCIKIHGSFQDITERKNAGIKVRDSEFRYRQIVETAQEGIWMLDENSETTFVNQKMCEIIGYPRDEMLGKTNFFFKDEADLQTANVALKRRKRGISETYKASFLTKDGRLIWTQISSNPIFDDANIYKGSLWMVSDITEKLMADKMLMESEQKHRKLASELEIERIRLVTAQSVAKVGSWETNLQTFQVNWSNETHRIFGSNPEKFEASHSAFLNFIHPEDREKVDAAFADSLHKSGSSTIEHRIITVQGIEKWVEEIWSVSRDEKGSPKIATGTCQDITASKKAADKVIRSEAKLNVAQYIAHVGSYEVDMVTDEQSWSDEFYRILGINSGVPPSREAFLSFVHPDDRPKVVSSMDEAYSLYEDSLIQFRFIRKNGAKGYASSEWKFEFDDQGNPLYLYGILRDLTKEKKAERERVKMISDIVQRNSDLEQFSYMVSHNLRAPTANIIGFADILQDDSISSQEQKELLQGLSASVKGLDTIIKDINIILQVEREVHEKKEVIIFSKLVNDIMLSIGNLIYKHRVIINRDFSAVDEIYSLKVYIYSIFYNLISNSIKYSKPNEQPRIEIKSKKENGKIILTFKDNGLGIDLKTKADKIFGLYNRFHSHVEGKGMGLFMVKKQVESLGGKITVASEPNQGTEFTIEFEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-06-17" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZMM3</accession>
    <name>A0A5C6ZMM3_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Helix-turn-helix transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ESY86_00330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="38"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="TXD91079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="95" mass="10841" checksum="65F98ED917136913" modified="2019-11-13" version="1">MKSYTLDQAEDLLIGKKGTEERDEYEFELKLELIGDMIKIARKKRKLTQEQLGALVGVKKAQISRLENSTGNVTFETVMRIFNALGAKLHLNLQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN16</accession>
    <name>A0A5C6ZN16_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Enoyl-CoA hydratase/isomerase family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_01870</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001753">
        <property type="entry name" value="Enoyl-CoA_hydra/iso"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00378">
        <property type="entry name" value="ECH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="250" mass="27413" checksum="58DFE52B279C440D" modified="2019-11-13" version="1">MTKPYVKQNIESEVAYIEFFHPAHNSLPGDILAKLAKTITEAGENDDIKVIVLKSGGDRTFCAGASFKELININDAETGKEFFSGFANVINAMRKCPKFIIGRIQGKTVGGGVGLAASTDYCMATKFSAIKLSELNLGIGPFVVGPVIERKIGLSAMSQIAIDANSFYEPEWAKQKGLFTQVYDSTEALDEAVKATAEHLCTYNPEAMIEMKKVFWTGTDNWDDLLAERAETSGRLVLSAFTKEKLKTYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZN75</accession>
    <name>A0A5C6ZN75_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Acyl-CoA dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ESY86_01575</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">2-80-2</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the acyl-CoA dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006091">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046373">
        <property type="entry name" value="Acyl-CoA_Oxase/DH_mid-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036250">
        <property type="entry name" value="AcylCo_DH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009075">
        <property type="entry name" value="AcylCo_DH/oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013786">
        <property type="entry name" value="AcylCoA_DH/ox_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037069">
        <property type="entry name" value="AcylCoA_DH/ox_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009100">
        <property type="entry name" value="AcylCoA_DH/oxidase_NM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00441">
        <property type="entry name" value="Acyl-CoA_dh_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02770">
        <property type="entry name" value="Acyl-CoA_dh_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02771">
        <property type="entry name" value="Acyl-CoA_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47203">
        <property type="entry name" value="SSF47203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56645">
        <property type="entry name" value="SSF56645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0274">FAD</keyword>
    <keyword evidence="3 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acyl-CoA_dh_N" evidence="8">
        <location>
            <begin position="7"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_M" evidence="7">
        <location>
            <begin position="135"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="Acyl-CoA_dh_1" evidence="6">
        <location>
            <begin position="248"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="TXD91299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="408" mass="45301" checksum="73D17CB31EF0858C" modified="2019-11-13" version="1">MNFDYSEKSIALQQKLKDFMETNVLPIEKEVELFHKNPDNAWKRWPGLEALKQKAKDAGLWNVFLPASYGDLSPGFSNLEYAPLAEIMGRIIWCSEIFNCSAPDTGNMEVLAKYGTPEQQEKWLKPLMNGDIRSAFLMTEPEVASSDATNIETSIIADGNDYVINGRKWWSSGAMDPNCKIAIVMGKTDFDAPRHVQQSMILVPMDTPGLKIERALSVFGYTDSPEGHAEITLENVRVPKTNLLLGEGRGFEIAQGRLGPGRIHHCMRLIGMAQRSLEIMSERTVQRKPFGRTLDTYSSVRQDIALSACEIEQTRLLVLSAADKMDKLGNKEAKDLIAMIKIVTPQMALRVIDRAIQILGGKGVGSDTPLAHFFAAARSLRLADGPDEVHMSQLGKSTINKYVKSSDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZNI6</accession>
    <name>A0A5C6ZNI6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF488 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_02635</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000002">
        <property type="protein sequence ID" value="TXD90874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007438">
        <property type="entry name" value="DUF488"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04343">
        <property type="entry name" value="DUF488"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD90874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="294" mass="35013" checksum="820DF3ABFADCED1B" modified="2019-11-13" version="1">MFYRRKLVFALLENFENGLEKTRLQKLVFLLTKKQKNPNYDFVPYRFGCYSYSLKADLQAMIKRDWITISERGYELKTENKYYNELRSDDKKIVDDTISLYGKMNTEQITKHTYLNFPYHAINSTIASDILPEKYYLLVQEAKPKTEETILFTLGYEGISLEEYLNRLIRNDVKLLVDVRRNPLSQKYGFSKKLLSSFCNNLGIEYLHIPEVGIDSSKRRELNTQKDYDILFDDYNKTVLEETIESQDYILRLLKKHKRIALTCFEADTCQCHRTHLAEKIKRLPTFKYKLQHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2019-11-13" modified="2020-02-26" version="3" xmlns="http://uniprot.org/uniprot">
    <accession>A0A5C6ZQU6</accession>
    <name>A0A5C6ZQU6_9FLAO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DUF3124 domain-containing protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ESY86_01360</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Subsaximicrobium wynnwilliamsii</name>
        <dbReference type="NCBI Taxonomy" id="291179"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Bacteroidetes</taxon>
            <taxon>Flavobacteriia</taxon>
            <taxon>Flavobacteriales</taxon>
            <taxon>Flavobacteriaceae</taxon>
            <taxon>Subsaximicrobium</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2019-08" db="EMBL/GenBank/DDBJ databases">
            <title>Genomes of Subsaximicrobium wynnwilliamsii strains.</title>
            <authorList>
                <person name="Bowman J.P."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">2-80-2</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="VORO01000001">
        <property type="protein sequence ID" value="TXD91263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000321578">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021471">
        <property type="entry name" value="DUF3124"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11322">
        <property type="entry name" value="DUF3124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="TXD91263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000321578"/>
        </source>
    </evidence>
    <sequence length="171" mass="19640" checksum="D776A08D0DAFB80F" modified="2019-11-13" version="1">MKHPILYLGLFFLLFLACEKTNPDEKRAVISDEHHLPQRTVETDSAFITKKVYVPVYSNIYQRTRNDRTSLTSTLSIHNTSETDTLYISRIDYFNTEGKLVRKYIEETIFLSTFETLEYVVDEGDETGGSGANFVIEWYGDKKLNPLFQAVMIGGLGNKSFSFTTEGVYFE</sequence>
</entry>
<copyright>
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms Distributed under the Creative Commons Attribution (CC BY 4.0) License
</copyright>
</uniprot>